# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SNAP PF14938.6 CCH57813.1 - 5.6 6.3 34.5 2.1 7.7 0.2 8.7 10 0 0 10 10 10 0 Soluble NSF attachment protein, SNAP Rad51 PF08423.11 CCH57814.1 - 9.4e-43 146.3 0.0 2.8e-42 144.8 0.0 1.7 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CCH57814.1 - 2.9e-06 27.0 0.0 5.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCH57814.1 - 8e-06 25.4 2.0 1.4e-05 24.6 0.5 2.2 2 1 0 2 2 2 1 KaiC RecA PF00154.21 CCH57814.1 - 8.7e-06 25.4 0.1 1.9e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein T2SSE PF00437.20 CCH57814.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 CCH57814.1 - 0.01 15.6 0.1 0.03 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain CRR7 PF12095.8 CCH57814.1 - 0.071 13.6 0.5 0.28 11.7 0.2 2.1 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 YabA PF06156.13 CCH57814.1 - 0.16 12.6 2.9 0.4 11.3 0.3 2.6 2 0 0 2 2 2 0 Initiation control protein YabA RCR PF12273.8 CCH57815.1 - 1.8e-25 89.9 0.1 3.5e-25 89.0 0.1 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF3328 PF11807.8 CCH57815.1 - 0.12 12.2 0.4 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Mannosyl_trans2 PF04188.13 CCH57816.1 - 3.5e-68 230.9 40.1 6.3e-53 180.7 34.3 2.6 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) Ran_BP1 PF00638.18 CCH57817.1 - 7.5e-53 178.0 2.2 1.5e-52 177.0 2.2 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CCH57817.1 - 0.00043 20.2 1.2 0.0034 17.3 1.2 2.1 1 1 0 1 1 1 1 WH1 domain Orthopox_F7 PF05813.12 CCH57817.1 - 2.1 8.5 7.3 0.21 11.7 2.7 1.7 2 0 0 2 2 2 0 Orthopoxvirus F7 protein HMG_box PF00505.19 CCH57818.1 - 2.6e-16 59.8 2.4 5.8e-16 58.7 2.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCH57818.1 - 5.3e-15 55.8 1.5 1.1e-14 54.8 1.5 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 CCH57818.1 - 0.01 15.8 0.5 0.022 14.7 0.5 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 UPF0254 PF06787.11 CCH57818.1 - 0.06 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) DUF155 PF02582.14 CCH57819.1 - 1.4e-54 184.8 0.9 2.8e-54 183.9 0.9 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CCH57819.1 - 0.032 14.7 1.1 0.092 13.2 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Thiamine_BP PF01910.17 CCH57820.1 - 6.4e-26 90.1 0.0 7.3e-26 89.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Tcp11 PF05794.13 CCH57821.1 - 1.6e-55 189.0 1.6 2.3e-54 185.2 1.6 2.0 1 1 0 1 1 1 1 T-complex protein 11 PAE PF03283.13 CCH57821.1 - 0.082 12.0 1.7 0.13 11.3 1.7 1.2 1 0 0 1 1 1 0 Pectinacetylesterase PRAI PF00697.22 CCH57822.1 - 1.2e-42 145.9 0.1 2.2e-42 145.0 0.1 1.4 1 1 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase NICE-1 PF15845.5 CCH57822.1 - 0.095 13.5 0.3 0.15 12.9 0.3 1.3 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family RT_RNaseH_2 PF17919.1 CCH57823.1 - 6e-15 55.1 0.0 1.7e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CCH57823.1 - 1.2e-10 41.3 0.2 3.6e-10 39.7 0.2 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH PF17917.1 CCH57823.1 - 1.2e-06 28.7 0.1 6.3e-06 26.4 0.0 2.1 3 0 0 3 3 3 1 RNase H-like domain found in reverse transcriptase Tfb5 PF06331.12 CCH57823.1 - 0.029 14.4 0.4 0.069 13.1 0.1 1.8 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 RVT_2 PF07727.14 CCH57825.1 - 6.7e-18 65.2 0.0 9.3e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EcoRII-N PF09217.10 CCH57825.1 - 0.0088 15.8 0.1 0.017 14.9 0.1 1.4 1 0 0 1 1 1 1 Restriction endonuclease EcoRII, N-terminal LMBR1 PF04791.16 CCH57825.1 - 0.3 10.0 2.5 0.37 9.6 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tubulin-binding PF00418.19 CCH57826.1 - 0.092 12.8 1.4 0.15 12.1 0.0 2.1 3 0 0 3 3 3 0 Tau and MAP protein, tubulin-binding repeat zf-ANAPC11 PF12861.7 CCH57827.1 - 5.1e-39 132.2 6.7 8.2e-39 131.6 6.7 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCH57827.1 - 1.1e-19 70.4 11.0 1.5e-19 70.0 11.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCH57827.1 - 1.5e-05 25.3 18.2 0.0003 21.1 18.2 2.6 1 1 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 CCH57827.1 - 0.00074 19.1 5.7 0.0015 18.1 5.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CCH57827.1 - 0.0012 18.7 4.7 0.0012 18.7 4.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH57827.1 - 0.011 15.7 13.4 0.31 11.0 14.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 CCH57827.1 - 0.027 14.6 11.6 0.12 12.6 11.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HIT PF04438.16 CCH57827.1 - 0.039 13.8 5.0 0.039 13.8 5.0 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-RING_4 PF14570.6 CCH57827.1 - 0.11 12.3 15.3 0.066 13.0 2.9 3.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CCH57827.1 - 0.13 12.3 10.3 1.1 9.4 7.4 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCH57827.1 - 0.19 11.6 13.3 0.12 12.2 8.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH57827.1 - 0.33 10.9 16.5 4.9 7.1 16.6 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 CCH57827.1 - 1.8 8.8 8.7 0.68 10.1 5.5 1.7 1 1 1 2 2 2 0 PHD-zinc-finger like domain RINGv PF12906.7 CCH57827.1 - 3.3 7.9 9.7 10 6.3 9.8 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CCH57827.1 - 3.8 7.9 11.4 20 5.6 11.4 2.1 1 1 0 1 1 1 0 RING-like domain Mannosyl_trans3 PF11051.8 CCH57828.1 - 1e-45 156.3 0.3 2.3e-45 155.1 0.3 1.7 1 0 0 1 1 1 1 Mannosyltransferase putative Zn_clus PF00172.18 CCH57829.1 - 8.4e-06 25.8 12.0 1.5e-05 25.0 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 CCH57829.1 - 1.5 8.6 14.6 0.29 10.9 9.6 2.1 2 0 0 2 2 2 0 Replication factor-A C terminal domain Zn_clus PF00172.18 CCH57830.1 - 5.2e-05 23.3 10.5 9.2e-05 22.5 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 CCH57830.1 - 1.9 8.2 5.4 2.2 8.0 2.4 2.2 2 0 0 2 2 2 0 Replication factor-A C terminal domain DEAD_2 PF06733.15 CCH57831.1 - 1.2e-48 165.1 6.6 2.7e-48 163.9 6.6 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CCH57831.1 - 1e-45 156.0 0.0 2.7e-45 154.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 CCH57831.1 - 0.00062 19.8 8.8 0.19 11.7 0.4 3.1 1 1 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCH57831.1 - 0.0021 18.3 0.8 2.2 8.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain DEAD PF00270.29 CCH57831.1 - 0.0027 17.5 1.5 0.28 10.9 0.6 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 CCH57831.1 - 0.016 14.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein IL5 PF02025.15 CCH57831.1 - 0.045 14.0 0.1 0.33 11.3 0.1 2.5 1 0 0 1 1 1 0 Interleukin 5 DUF743 PF05332.11 CCH57833.1 - 0.012 15.7 0.8 0.012 15.7 0.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF743) C5-epim_C PF06662.13 CCH57833.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus NAC PF01849.18 CCH57834.1 - 8.3e-15 54.5 0.6 8.3e-15 54.5 0.6 1.6 2 0 0 2 2 2 1 NAC domain RPAP1_N PF08621.10 CCH57834.1 - 0.055 13.2 0.8 7.3 6.5 0.1 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal DUF755 PF05501.11 CCH57834.1 - 0.35 11.1 5.4 1.3 9.3 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) zf-C2H2 PF00096.26 CCH57835.1 - 3.6e-10 39.7 7.6 0.00034 20.9 2.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH57835.1 - 7.1e-08 32.6 5.5 0.0049 17.6 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCH57835.1 - 0.003 17.5 4.4 0.049 13.7 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH57835.1 - 0.0035 17.6 4.3 0.22 11.9 0.0 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 CCH57835.1 - 0.038 14.7 1.0 0.47 11.1 0.2 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CCH57835.1 - 0.15 11.8 2.3 0.67 9.8 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CCH57835.1 - 1.5 9.4 8.6 0.23 12.0 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 CCH57835.1 - 2 8.6 4.3 4 7.6 3.1 2.1 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 CCH57835.1 - 4.6 7.2 8.2 0.32 10.9 3.2 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-H2C2_5 PF13909.6 CCH57835.1 - 6.5 6.6 6.8 17 5.3 3.0 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF1400 PF07176.11 CCH57836.1 - 0.035 14.4 0.4 0.52 10.6 0.4 2.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) FLILHELTA PF10306.9 CCH57837.1 - 2.5e-21 75.9 0.1 4.8e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Vps16_C PF04840.12 CCH57838.1 - 2.3e-70 237.2 20.8 2.3e-70 237.2 20.8 2.4 2 0 0 2 2 2 1 Vps16, C-terminal region Vps16_N PF04841.13 CCH57838.1 - 1.9e-44 152.1 3.5 3.2e-44 151.3 3.5 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Skp1_POZ PF03931.15 CCH57839.1 - 3.8e-07 30.2 1.4 3.8e-07 30.2 1.4 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CCH57839.1 - 0.0042 17.3 0.1 0.005 17.1 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain Sgf11 PF08209.11 CCH57840.1 - 9.7e-15 53.8 3.5 1.3e-14 53.4 3.5 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Sgf11_N PF18519.1 CCH57840.1 - 2.3e-05 23.8 2.4 3.7e-05 23.2 2.4 1.3 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain zf-CpG_bind_C PF12269.8 CCH57840.1 - 0.027 14.3 0.1 0.027 14.3 0.1 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Suc_Fer-like PF06999.12 CCH57840.1 - 0.12 12.3 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Catalase PF00199.19 CCH57841.1 - 3.5e-185 615.6 1.8 4.3e-185 615.3 1.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCH57841.1 - 5.8e-12 45.7 0.1 2.3e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Peptidase_C48 PF02902.19 CCH57842.1 - 0.0099 15.7 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GST_N PF02798.20 CCH57843.1 - 4.9e-14 52.4 0.1 1.2e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCH57843.1 - 1.7e-12 47.4 0.0 2.7e-12 46.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH57843.1 - 1.7e-10 40.8 0.1 3.1e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCH57843.1 - 1.7e-08 34.6 0.0 9.1e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCH57843.1 - 1.6e-06 28.4 0.0 3.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CCH57843.1 - 0.00045 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TFIIA PF03153.13 CCH57844.1 - 0.0022 18.1 32.6 0.0022 18.1 32.6 2.6 1 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Herpes_LMP2 PF07415.11 CCH57844.1 - 6.3 5.5 7.4 11 4.6 7.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Arf PF00025.21 CCH57845.1 - 9.6e-46 155.4 0.5 1.2e-45 155.1 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCH57845.1 - 4.5e-15 55.9 0.1 6.7e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCH57845.1 - 1.5e-14 53.9 0.1 1.9e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCH57845.1 - 3.6e-13 49.3 0.2 4.6e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCH57845.1 - 3.2e-11 43.0 1.4 8.4e-08 31.8 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCH57845.1 - 9.1e-09 35.0 0.1 1.1e-08 34.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH57845.1 - 6.6e-08 32.6 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH57845.1 - 1.8e-07 30.9 0.1 3.1e-07 30.1 0.1 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCH57845.1 - 0.02 14.8 0.3 0.93 9.4 0.0 2.4 1 1 2 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 CCH57845.1 - 0.02 15.2 0.1 0.12 12.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 CCH57845.1 - 0.021 14.5 0.1 0.052 13.2 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.6 CCH57845.1 - 0.04 14.3 0.0 0.071 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CCH57845.1 - 0.048 13.6 0.1 0.09 12.7 0.1 1.6 1 1 1 2 2 2 0 NACHT domain AAA_24 PF13479.6 CCH57845.1 - 0.051 13.3 0.2 0.086 12.6 0.2 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 CCH57845.1 - 0.064 13.3 1.1 0.12 12.4 0.6 1.6 1 1 1 2 2 2 0 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 CCH57845.1 - 0.073 13.6 0.0 0.095 13.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CCH57845.1 - 0.075 12.4 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 CCH57845.1 - 0.08 13.5 0.2 0.25 11.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 CCH57845.1 - 0.13 12.7 0.1 0.34 11.3 0.0 1.7 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) Glyco_transf_15 PF01793.16 CCH57847.1 - 5.1e-121 403.9 18.5 5.1e-121 403.9 18.5 1.8 1 1 1 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase DUF512 PF04459.12 CCH57847.1 - 0.037 13.3 1.5 0.066 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Glyco_transf_15 PF01793.16 CCH57848.1 - 1.1e-122 409.4 8.7 1.6e-122 408.9 8.7 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DNA_pol_B_N PF18094.1 CCH57848.1 - 0.056 14.0 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 DNA polymerase beta N-terminal domain Gly_transf_sug PF04488.15 CCH57849.1 - 1.6e-24 86.4 0.4 3.9e-24 85.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3270 PF11674.8 CCH57849.1 - 6.5 7.0 6.7 3.9 7.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) DUF2401 PF10287.9 CCH57850.1 - 2.8e-90 301.9 2.2 5e-90 301.1 2.2 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCH57850.1 - 3e-26 91.6 0.1 8.5e-26 90.2 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) RAMP4 PF06624.12 CCH57851.1 - 3e-11 43.2 0.4 3.4e-11 43.0 0.4 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3394 PF11874.8 CCH57851.1 - 0.067 12.9 0.0 0.081 12.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Peptidase_A2B PF12384.8 CCH57852.1 - 3.5e-12 46.2 0.0 6.2e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 CCH57852.1 - 4.5e-07 30.3 0.0 7.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCH57852.1 - 1.9e-05 25.2 0.0 3.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 CCH57852.1 - 0.00034 20.4 0.1 0.00082 19.2 0.1 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease RT_RNaseH_2 PF17919.1 CCH57853.1 - 2.3e-27 94.9 0.0 4.4e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH57853.1 - 1.9e-25 89.1 0.0 4e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CCH57854.1 - 3.2e-09 37.0 0.0 5.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain NIF PF03031.18 CCH57855.1 - 8.9e-43 145.8 0.3 1.6e-42 145.0 0.3 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CTI PF06934.11 CCH57855.1 - 0.01 14.4 0.4 0.016 13.8 0.4 1.2 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) NDUF_B5 PF09781.9 CCH57855.1 - 0.66 9.5 4.0 0.34 10.5 1.0 2.2 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Pro_isomerase PF00160.21 CCH57856.1 - 1.7e-09 38.2 0.0 7.2e-08 32.9 0.0 2.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cmc1 PF08583.10 CCH57856.1 - 0.069 13.2 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like VPS28 PF03997.12 CCH57857.1 - 6.6e-75 250.9 3.0 7.7e-75 250.7 3.0 1.0 1 0 0 1 1 1 1 VPS28 protein Spectrin_like PF18373.1 CCH57857.1 - 0.046 13.8 0.8 5.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Spectrin like domain N6_N4_Mtase PF01555.18 CCH57857.1 - 0.063 13.0 1.9 0.13 12.0 1.9 1.6 1 1 0 1 1 1 0 DNA methylase MCM PF00493.23 CCH57859.1 - 1.5e-103 344.8 0.0 2.3e-103 344.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCH57859.1 - 9.9e-33 112.7 0.6 1.8e-32 111.8 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCH57859.1 - 3.7e-22 78.5 2.9 6.8e-22 77.7 1.4 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CCH57859.1 - 1.5e-16 60.8 2.5 1.9e-16 60.5 0.7 2.2 2 1 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCH57859.1 - 1.1e-07 31.5 0.1 3.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCH57859.1 - 1.7e-06 28.1 0.0 2.4e-05 24.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CCH57859.1 - 8.9e-05 22.3 0.1 0.00035 20.4 0.1 2.0 2 0 0 2 2 2 1 AAA lid domain Mg_chelatase_C PF13335.6 CCH57859.1 - 0.00031 21.3 0.5 0.0012 19.4 0.3 2.1 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 CCH57859.1 - 0.013 15.4 0.0 0.069 13.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Phage_int_SAM_5 PF13102.6 CCH57859.1 - 0.054 13.8 1.8 0.14 12.5 0.0 2.5 2 0 0 2 2 2 0 Phage integrase SAM-like domain AAA_16 PF13191.6 CCH57859.1 - 0.19 12.1 2.8 3.6 7.9 0.0 3.5 3 1 1 4 4 4 0 AAA ATPase domain DER1 PF04511.15 CCH57860.1 - 4.7e-38 131.0 10.3 5.8e-38 130.8 10.3 1.1 1 0 0 1 1 1 1 Der1-like family Kei1 PF08552.11 CCH57860.1 - 0.00015 21.7 1.2 0.00036 20.5 1.2 1.8 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 CCH57860.1 - 5 5.8 14.8 9.9 4.8 14.8 1.6 1 0 0 1 1 1 0 Presenilin polyprenyl_synt PF00348.17 CCH57861.1 - 8.8e-50 169.1 0.0 1.1e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase PET122 PF05476.11 CCH57861.1 - 0.0053 16.1 0.2 0.014 14.7 0.2 1.7 1 0 0 1 1 1 1 PET122 TEBP_beta PF07404.11 CCH57861.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) SH3_1 PF00018.28 CCH57862.1 - 1.7e-14 53.1 0.1 7.3e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.24 CCH57862.1 - 1.2e-13 51.0 0.1 2.9e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 CCH57862.1 - 1.8e-12 46.9 0.8 6.6e-05 22.7 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CCH57862.1 - 4.9e-07 29.3 0.1 0.0034 17.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 CCH57862.1 - 0.00026 20.9 0.0 0.00056 19.8 0.0 1.5 1 0 0 1 1 1 1 PB1 domain Hydantoinase_B PF02538.14 CCH57863.1 - 1.8e-200 666.7 0.0 2.3e-200 666.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CCH57863.1 - 3.9e-100 334.9 0.0 1e-99 333.5 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CCH57863.1 - 1.2e-55 187.9 0.3 9.7e-54 181.8 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Aldo_ket_red PF00248.21 CCH57864.1 - 1.3e-38 132.9 0.0 1.7e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Mannosyl_trans3 PF11051.8 CCH57865.1 - 4.9e-70 236.0 0.8 7.2e-70 235.5 0.8 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative GSHPx PF00255.19 CCH57868.1 - 5.7e-31 106.3 0.3 7.4e-31 105.9 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 CCH57868.1 - 0.0033 17.1 0.0 0.0068 16.1 0.0 1.5 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CCH57868.1 - 0.01 15.8 0.1 0.03 14.3 0.1 1.7 1 1 0 1 1 1 0 AhpC/TSA family DUF4174 PF13778.6 CCH57868.1 - 0.051 14.1 0.0 0.099 13.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Pan3_PK PF18101.1 CCH57869.1 - 1e-50 171.3 1.3 1e-50 171.3 1.3 1.9 2 0 0 2 2 2 1 Pan3 Pseudokinase domain LuxT_C PF18285.1 CCH57869.1 - 0.096 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain Ank_2 PF12796.7 CCH57870.1 - 5e-11 43.0 2.8 6.2e-11 42.7 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCH57870.1 - 3.4e-10 40.3 0.2 2e-09 37.8 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CCH57870.1 - 1.3e-09 38.1 0.1 0.00014 22.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CCH57870.1 - 4.4e-09 35.8 0.2 7.6e-05 22.8 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CCH57870.1 - 5.6e-07 29.7 0.0 5.6e-07 29.7 0.0 5.5 5 1 0 5 5 5 1 Ankyrin repeats (many copies) PPTA PF01239.22 CCH57871.1 - 9.6e-32 107.8 23.2 1.3e-06 27.9 0.2 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Bacteriocin_IIi PF11758.8 CCH57871.1 - 0.017 14.9 1.0 0.13 12.1 0.1 2.7 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin DUF3373 PF11853.8 CCH57871.1 - 0.034 13.3 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) BTP PF05232.12 CCH57871.1 - 0.12 12.4 0.2 0.21 11.7 0.2 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter DSPc PF00782.20 CCH57872.1 - 2.2e-25 89.0 3.9 6.9e-25 87.4 0.7 2.7 2 2 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCH57872.1 - 0.00093 18.8 0.1 0.0027 17.3 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Elf1 PF05129.13 CCH57872.1 - 0.0062 16.6 3.6 2.7 8.1 0.2 3.2 2 1 0 2 2 2 2 Transcription elongation factor Elf1 like PTPlike_phytase PF14566.6 CCH57872.1 - 0.03 14.4 0.0 0.077 13.1 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Ribonuc_red_2_N PF08471.10 CCH57872.1 - 0.068 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase Yippee-Mis18 PF03226.14 CCH57872.1 - 0.094 12.9 1.5 0.5 10.6 1.5 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF35_N PF12172.8 CCH57872.1 - 0.12 12.3 5.9 0.52 10.2 0.0 3.3 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_ribbon_SprT PF17283.2 CCH57872.1 - 0.44 10.5 0.1 0.44 10.5 0.1 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain zinc_ribbon_4 PF13717.6 CCH57872.1 - 2.6 8.0 5.7 17 5.5 0.7 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Apc15p PF05841.11 CCH57873.1 - 2.4e-31 109.1 2.0 2.4e-31 109.1 2.0 3.9 2 2 2 4 4 4 1 Apc15p protein Fungal_trans PF04082.18 CCH57874.1 - 7.1e-15 54.7 0.1 3e-14 52.7 0.1 2.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH57874.1 - 4.5e-07 29.9 11.4 9.3e-07 28.9 11.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtIP_N PF10482.9 CCH57874.1 - 0.0022 18.1 0.8 0.0022 18.1 0.8 1.8 2 0 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain YabA PF06156.13 CCH57874.1 - 0.024 15.3 1.4 0.091 13.4 1.4 2.0 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 CCH57874.1 - 0.038 14.2 3.1 0.091 13.0 3.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper HMMR_C PF15908.5 CCH57874.1 - 0.07 13.4 0.9 0.14 12.4 0.9 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal bZIP_1 PF00170.21 CCH57874.1 - 0.32 11.1 3.4 0.91 9.7 3.4 1.8 1 0 0 1 1 1 0 bZIP transcription factor Fungal_TACC PF12709.7 CCH57874.1 - 3 8.4 8.2 0.18 12.3 1.5 2.5 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins HAP1_N PF04849.13 CCH57874.1 - 3.1 6.9 6.1 0.14 11.3 0.5 1.5 2 0 0 2 2 2 0 HAP1 N-terminal conserved region Npa1 PF11707.8 CCH57875.1 - 2.6e-79 267.0 7.4 2.6e-79 267.0 7.4 3.2 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CCH57875.1 - 1.7e-43 148.6 0.5 1.7e-43 148.6 0.5 3.0 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 DUF5321 PF17254.2 CCH57876.1 - 0.0045 16.4 8.7 0.11 12.0 0.8 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5321) zf-C4H2 PF10146.9 CCH57876.1 - 0.062 13.6 10.9 0.12 12.7 10.9 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein ARPC4 PF05856.12 CCH57877.1 - 2.4e-74 248.5 4.3 2.7e-74 248.3 4.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Resolvase PF00239.21 CCH57877.1 - 0.072 13.2 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain ParBc PF02195.18 CCH57878.1 - 5.1e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 1 0 1 1 1 1 ParB-like nuclease domain Ank_2 PF12796.7 CCH57879.1 - 4.3e-26 91.3 1.6 9.9e-10 38.9 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCH57879.1 - 1.7e-21 76.3 2.0 1.2e-08 35.3 0.2 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CCH57879.1 - 1.7e-13 50.4 8.2 0.00066 20.0 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CCH57879.1 - 4.1e-12 45.2 4.1 0.095 13.3 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CCH57879.1 - 4.7e-06 26.8 0.6 0.0017 18.6 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) SPACA9 PF15120.6 CCH57880.1 - 0.053 13.3 3.9 0.07 12.9 2.1 2.2 2 1 0 2 2 2 0 Sperm acrosome-associated protein 9 ERM PF00769.19 CCH57880.1 - 0.21 11.4 7.2 0.53 10.1 7.2 1.7 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PPR_3 PF13812.6 CCH57880.1 - 0.25 11.4 4.2 10 6.3 0.1 3.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain DUF948 PF06103.11 CCH57880.1 - 0.63 10.3 2.2 32 4.9 0.1 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) PPR_2 PF13041.6 CCH57880.1 - 1.1 9.6 7.0 1.7 8.9 0.0 3.8 4 0 0 4 4 4 0 PPR repeat family SURF6 PF04935.12 CCH57881.1 - 5.9e-45 153.5 57.0 5.9e-45 153.5 57.0 2.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CCH57881.1 - 3.5e-11 43.5 4.1 3.5e-11 43.5 4.1 8.1 4 2 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Androgen_recep PF02166.16 CCH57881.1 - 1.1 8.1 7.6 1.9 7.2 7.6 1.3 1 0 0 1 1 1 0 Androgen receptor CX PF01705.19 CCH57881.1 - 2.4 8.7 4.1 0.9 10.1 0.2 2.3 2 0 0 2 2 2 0 CX module V-ATPase_C PF03223.15 CCH57882.1 - 1.6e-120 402.9 3.5 1.8e-120 402.8 3.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2666 PF10869.8 CCH57882.1 - 0.059 13.6 1.1 2.8 8.1 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Kinesin PF00225.23 CCH57883.1 - 1.2e-45 155.9 12.0 4.3e-45 154.1 12.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCH57883.1 - 9.6e-14 51.6 1.0 1.1e-11 44.8 0.5 3.6 4 0 0 4 4 4 2 Microtubule binding Mto2_bdg PF12808.7 CCH57883.1 - 0.059 13.7 1.6 0.31 11.4 1.7 2.3 1 1 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NDK PF00334.19 CCH57884.1 - 5.3e-56 188.4 0.0 5.9e-56 188.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_M22 PF00814.25 CCH57885.1 - 9.5e-82 274.7 0.0 1.2e-81 274.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family PIR PF00399.19 CCH57887.1 - 2.6e-34 116.0 50.5 3.9e-09 35.8 3.5 5.0 4 0 0 4 4 4 4 Yeast PIR protein repeat BAP PF06639.11 CCH57887.1 - 5 7.5 6.0 0.77 10.1 0.8 2.3 1 1 0 2 2 2 0 Basal layer antifungal peptide (BAP) NESP55 PF06390.12 CCH57889.1 - 1.8 8.1 7.2 2.4 7.7 7.2 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) DNA_primase_S PF01896.19 CCH57890.1 - 6.9e-63 211.9 1.9 1e-62 211.3 1.9 1.3 1 0 0 1 1 1 1 DNA primase small subunit Cellulase PF00150.18 CCH57891.1 - 2.8e-14 53.2 0.8 3.5e-08 33.2 0.3 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 CCH57891.1 - 3.4e-06 27.5 0.0 1.2e-05 25.7 0.0 2.0 1 1 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain WSC PF01822.19 CCH57892.1 - 6.7e-11 42.2 16.8 6.7e-11 42.2 16.8 3.2 2 1 0 2 2 2 1 WSC domain DUF2408 PF10303.9 CCH57893.1 - 4.2e-57 192.5 24.3 5.3e-39 133.9 2.7 5.1 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) MLD PF11647.8 CCH57893.1 - 0.035 14.4 4.2 0.96 9.8 0.3 3.6 4 0 0 4 4 4 0 Membrane Localization Domain AhpC-TSA PF00578.21 CCH57894.1 - 3e-31 107.9 0.0 7.5e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCH57894.1 - 8.4e-20 71.0 0.1 2e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CCH57894.1 - 0.012 15.7 0.3 0.034 14.3 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA antioxidant enzyme CAC1F_C PF16885.5 CCH57894.1 - 1.5 8.4 10.9 1.8 8.1 10.9 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term CCDC71L PF15374.6 CCH57894.1 - 4.8 6.3 26.1 1.5 8.0 23.3 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L Dsh_C PF12316.8 CCH57894.1 - 5 7.5 7.0 8 6.8 7.0 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal V_ATPase_I PF01496.19 CCH57894.1 - 7.1 4.4 8.2 8.4 4.2 8.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SLC12 PF03522.15 CCH57894.1 - 8.3 5.3 18.3 12 4.8 18.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Adap_comp_sub PF00928.21 CCH57895.1 - 7.2e-90 300.9 2.0 1e-89 300.4 2.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCH57895.1 - 3.3e-08 33.6 1.0 6.5e-08 32.6 1.0 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CCH57895.1 - 0.00048 19.7 0.1 0.0026 17.3 0.0 2.0 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain HBB PF06777.11 CCH57895.1 - 0.062 13.0 0.2 0.095 12.4 0.2 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF4442 PF14539.6 CCH57895.1 - 0.095 12.8 0.1 2.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) TPP1 PF10341.9 CCH57896.1 - 2.9e-22 78.8 2.2 5e-22 78.0 2.2 1.5 1 1 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD DUF2222 PF09984.9 CCH57896.1 - 0.0035 17.3 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised signal transduction histidine kinase domain (DUF2222) Nas2_N PF18265.1 CCH57897.1 - 2.5e-22 78.6 0.8 4.2e-22 77.8 0.8 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 CCH57897.1 - 0.00017 21.9 0.0 0.00039 20.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 CCH57897.1 - 0.00098 19.5 0.0 0.0024 18.2 0.0 1.6 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 CCH57897.1 - 0.012 15.9 0.1 0.025 14.9 0.1 1.6 1 0 0 1 1 1 0 PDZ domain DUF3710 PF12502.8 CCH57897.1 - 0.054 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) bZIP_2 PF07716.15 CCH57898.1 - 3.9e-12 46.1 8.7 8.9e-12 44.9 8.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CCH57898.1 - 6.8e-09 35.7 7.1 6.8e-09 35.7 7.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor ZapB PF06005.12 CCH57898.1 - 0.0088 16.5 7.8 0.017 15.5 1.9 2.4 2 0 0 2 2 2 1 Cell division protein ZapB bZIP_Maf PF03131.17 CCH57898.1 - 0.033 14.7 5.7 0.033 14.7 5.7 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF848 PF05852.11 CCH57898.1 - 0.46 10.6 4.6 0.82 9.8 0.9 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FAM76 PF16046.5 CCH57898.1 - 1.3 8.3 7.6 0.24 10.7 0.5 2.3 2 0 0 2 2 2 0 FAM76 protein Gti1_Pac2 PF09729.9 CCH57899.1 - 1.9e-53 181.3 1.3 1.9e-53 181.3 1.3 3.3 2 1 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.27 CCH57900.1 - 7.1e-69 227.8 2.5 7.5e-24 83.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF515 PF04415.12 CCH57900.1 - 0.08 11.3 3.7 0.32 9.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Thioredoxin PF00085.20 CCH57901.1 - 9.6e-26 89.8 6.3 1.1e-21 76.7 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CCH57901.1 - 0.0014 18.6 15.9 0.0019 18.2 0.2 4.7 3 3 1 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CCH57901.1 - 0.005 16.2 3.4 0.024 14.0 0.3 3.3 4 0 0 4 4 4 1 OST3 / OST6 family, transporter family Use1 PF09753.9 CCH57902.1 - 6.6e-05 22.7 0.0 8.1e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 TraG_N PF07916.11 CCH57902.1 - 0.048 12.5 0.0 0.049 12.5 0.0 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2207 PF09972.9 CCH57902.1 - 0.059 12.1 0.1 0.06 12.1 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SH3BP5 PF05276.14 CCH57902.1 - 0.069 12.9 0.2 0.13 12.1 0.1 1.3 1 1 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF1054 PF06335.12 CCH57902.1 - 0.12 12.3 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Spore_III_AB PF09548.10 CCH57902.1 - 0.14 12.3 0.1 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Lectin_N PF03954.14 CCH57902.1 - 0.22 11.3 1.4 1.4 8.7 0.1 2.1 1 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Synaptobrevin PF00957.21 CCH57902.1 - 2.8 7.8 4.9 6.1 6.7 4.9 1.8 1 1 0 1 1 1 0 Synaptobrevin ParA PF10609.9 CCH57903.1 - 8.7e-97 323.4 0.0 9.8e-97 323.2 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCH57903.1 - 9e-10 38.7 0.0 5.5e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCH57903.1 - 6e-07 29.6 0.7 3.1e-06 27.2 0.2 2.2 2 1 0 2 2 2 1 AAA domain MipZ PF09140.11 CCH57903.1 - 1.7e-06 27.6 0.0 1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CCH57903.1 - 0.00011 21.5 0.3 0.00011 21.5 0.3 1.9 3 0 0 3 3 3 1 Anion-transporting ATPase MeaB PF03308.16 CCH57903.1 - 0.0096 14.9 0.3 0.014 14.4 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 CCH57903.1 - 0.0099 15.4 0.1 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CCH57903.1 - 0.032 13.7 0.0 0.064 12.7 0.0 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 CCH57903.1 - 0.048 13.6 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 CCH57903.1 - 0.14 11.7 0.3 0.23 11.0 0.3 1.2 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 CCH57904.1 - 7e-16 57.8 0.4 1.6e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CCH57904.1 - 0.056 13.4 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nop16 PF09420.10 CCH57905.1 - 5.1e-68 229.2 15.0 6.3e-68 228.9 15.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Trypan_glycop PF00913.19 CCH57905.1 - 0.12 11.6 0.8 0.18 11.0 0.8 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF4142 PF13628.6 CCH57905.1 - 0.14 12.4 1.5 0.23 11.7 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) GDA1_CD39 PF01150.17 CCH57906.1 - 1.9e-145 484.7 0.7 2.6e-145 484.3 0.7 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CCH57906.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Vezatin PF12632.7 CCH57906.1 - 0.026 13.9 0.7 0.046 13.1 0.7 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Pre-PUA PF17832.1 CCH57907.1 - 2.4e-25 89.0 2.3 4.8e-25 88.0 2.3 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CCH57907.1 - 1.1e-20 73.4 0.0 1.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CCH57907.1 - 0.00045 20.5 0.9 0.00045 20.5 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) Membrane_bind PF14564.6 CCH57907.1 - 0.056 13.9 0.1 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Membrane binding Sec3_C PF09763.9 CCH57908.1 - 8.8e-136 454.1 36.9 8.8e-136 454.1 36.9 2.7 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CCH57908.1 - 1.1e-23 83.2 4.2 4.2e-22 78.1 2.9 3.0 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH mCpol PF18182.1 CCH57908.1 - 0.062 13.6 0.8 0.36 11.2 0.1 2.7 2 0 0 2 2 2 0 minimal CRISPR polymerase domain NTF2 PF02136.20 CCH57909.1 - 4e-37 127.5 0.4 4.4e-37 127.3 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 CCH57909.1 - 4.9e-05 22.6 0.4 0.00015 21.1 0.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.6 CCH57909.1 - 0.021 15.2 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DnaJ-X PF14308.6 CCH57910.1 - 1.3e-67 227.4 0.9 1.3e-67 227.4 0.9 2.6 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCH57910.1 - 4e-26 90.9 2.3 1.5e-25 89.1 2.3 2.1 1 0 0 1 1 1 1 DnaJ domain SOBP PF15279.6 CCH57910.1 - 0.087 13.4 3.9 0.2 12.2 3.9 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 CCH57910.1 - 7.7 5.6 5.4 12 5.0 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CCH57910.1 - 9 4.9 14.2 17 4.0 14.2 1.3 1 0 0 1 1 1 0 Presenilin SRP1_TIP1 PF00660.17 CCH57911.1 - 3.4e-25 88.0 1.9 3.4e-25 88.0 1.9 1.8 2 0 0 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.19 CCH57911.1 - 5.5e-06 25.8 7.0 5.5e-06 25.8 7.0 2.8 2 0 0 2 2 1 1 Yeast PIR protein repeat XRN_M PF17846.1 CCH57911.1 - 0.041 12.8 4.2 0.06 12.3 4.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain NADH_u_ox_C PF12853.7 CCH57911.1 - 0.066 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit MotY_N PF18393.1 CCH57911.1 - 0.15 12.2 6.9 0.49 10.5 0.9 2.3 1 1 1 2 2 2 0 MotY N-terminal domain GREB1 PF15782.5 CCH57911.1 - 0.22 8.6 9.6 0.22 8.6 9.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIN_8 PF18476.1 CCH57911.1 - 0.57 10.0 4.7 0.76 9.6 4.7 1.3 1 0 0 1 1 1 0 PIN like domain DUF966 PF06136.13 CCH57911.1 - 0.67 9.6 13.8 0.81 9.3 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Nucleo_P87 PF07267.11 CCH57911.1 - 0.77 8.5 9.1 0.78 8.5 9.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 CCH57911.1 - 0.83 8.4 14.4 1.1 7.9 14.4 1.2 1 0 0 1 1 1 0 Presenilin PARM PF17061.5 CCH57911.1 - 0.94 9.6 33.4 1.7 8.7 33.4 1.4 1 0 0 1 1 1 0 PARM RR_TM4-6 PF06459.12 CCH57911.1 - 1.3 8.8 17.2 1.7 8.4 17.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CCH57911.1 - 1.5 8.7 9.0 2.1 8.3 9.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SAPS PF04499.15 CCH57911.1 - 2.3 6.9 11.0 2.6 6.7 11.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 CCH57911.1 - 2.7 8.0 8.5 3.4 7.7 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOG2 PF10428.9 CCH57911.1 - 3.1 6.9 21.5 3.7 6.6 21.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 CCH57911.1 - 3.2 6.2 10.6 3.7 6.0 10.6 1.1 1 0 0 1 1 1 0 Macoilin family Mitofilin PF09731.9 CCH57911.1 - 3.3 6.4 21.8 4.6 6.0 21.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Endostatin PF06482.11 CCH57911.1 - 3.8 6.9 9.4 4.5 6.6 9.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 CCH57911.1 - 4 6.3 10.7 6.3 5.7 10.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 CCH57911.1 - 4.1 5.4 15.3 4.7 5.2 15.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CCH57911.1 - 5.4 5.9 12.7 6.7 5.6 12.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 CCH57911.1 - 5.7 6.0 9.6 7.7 5.6 9.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 CCH57911.1 - 9.7 6.3 11.6 14 5.8 11.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SRP1_TIP1 PF00660.17 CCH57912.1 - 2.8e-35 120.3 0.2 4.8e-35 119.6 0.2 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family DUF533 PF04391.12 CCH57912.1 - 0.16 11.5 4.3 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) RraA-like PF03737.15 CCH57913.1 - 2.4e-30 105.7 0.0 3e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA ILEI PF15711.5 CCH57913.1 - 0.0034 17.8 0.1 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 Interleukin-like EMT inducer SRP1_TIP1 PF00660.17 CCH57914.1 - 2.9e-25 88.2 1.2 2.9e-25 88.2 1.2 2.0 1 1 1 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.19 CCH57914.1 - 2e-06 27.2 6.0 2e-06 27.2 6.0 2.4 2 0 0 2 2 2 1 Yeast PIR protein repeat COG2 PF06148.11 CCH57914.1 - 0.025 14.7 2.2 1.4 9.0 0.4 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIVA PF05103.13 CCH57914.1 - 0.053 13.6 2.6 0.1 12.7 2.6 1.5 1 0 0 1 1 1 0 DivIVA protein Apolipoprotein PF01442.18 CCH57914.1 - 0.063 13.1 0.7 0.13 12.1 0.7 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain LPP PF04728.13 CCH57914.1 - 0.22 11.9 0.3 0.22 11.9 0.3 3.1 3 1 1 4 4 4 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 CCH57914.1 - 0.27 11.6 1.8 1.7 9.1 0.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC2_membrane PF01061.24 CCH57915.1 - 4.3e-60 202.7 66.0 3e-31 108.5 29.6 2.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CCH57915.1 - 9e-34 116.9 0.0 1.4e-17 64.5 0.1 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCH57915.1 - 7.1e-25 86.7 5.6 3e-22 78.3 0.4 3.8 4 0 0 4 4 3 2 CDR ABC transporter RsgA_GTPase PF03193.16 CCH57915.1 - 3.9e-05 23.6 0.2 8.9e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CCH57915.1 - 5.4e-05 23.1 3.9 0.013 15.3 0.6 2.9 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH57915.1 - 5.9e-05 22.6 0.0 0.002 17.6 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CCH57915.1 - 0.00021 20.5 16.8 0.00021 20.5 16.8 3.8 4 0 0 4 4 4 2 ABC-2 family transporter protein AAA_16 PF13191.6 CCH57915.1 - 0.0064 16.9 0.2 0.031 14.7 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CCH57915.1 - 0.0088 16.6 1.9 0.013 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain UBA_e1_thiolCys PF10585.9 CCH57915.1 - 0.011 15.7 0.2 0.027 14.4 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site AAA_22 PF13401.6 CCH57915.1 - 0.028 14.7 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH57915.1 - 0.072 13.6 0.0 0.35 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCH57915.1 - 0.077 12.8 0.9 0.28 10.9 0.6 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 CCH57915.1 - 0.3 10.7 1.4 0.5 9.9 0.7 1.7 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mannosyl_trans3 PF11051.8 CCH57916.1 - 1.7e-69 234.3 2.1 2.7e-69 233.6 2.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative HMG_box PF00505.19 CCH57917.1 - 6.5e-11 42.5 2.4 1.6e-10 41.3 2.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCH57917.1 - 7.5e-06 26.4 1.9 7.5e-06 26.4 1.9 1.9 1 1 0 1 1 1 1 HMG-box domain PIR PF00399.19 CCH57919.1 - 5.4e-18 64.0 17.2 3.1e-09 36.1 3.5 3.0 2 0 0 2 2 2 2 Yeast PIR protein repeat DUF4942 PF13708.6 CCH57919.1 - 0.084 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Mpv17_PMP22 PF04117.12 CCH57920.1 - 4.8e-20 71.5 1.2 9.6e-20 70.6 0.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Zn_clus PF00172.18 CCH57921.1 - 7.1e-08 32.4 10.4 1.5e-07 31.4 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.19 CCH57922.1 - 1.5e-22 80.0 15.9 1.5e-22 80.0 15.9 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CCH57922.1 - 2.8e-16 60.0 0.0 5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CCH57922.1 - 5.9e-09 36.0 0.1 1.9e-08 34.3 0.1 1.9 1 0 0 1 1 1 1 FAD-binding domain Lipoprotein_15 PF03640.15 CCH57922.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Secreted repeat of unknown function Sugar_tr PF00083.24 CCH57923.1 - 1.1e-160 535.5 28.3 1.2e-160 535.2 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH57923.1 - 1.4e-31 109.8 30.9 2e-29 102.6 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH57923.1 - 1.9e-06 26.6 2.2 1.9e-06 26.6 2.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 CCH57923.1 - 0.61 10.4 6.8 0.82 10.0 0.6 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF2530 PF10745.9 CCH57923.1 - 2.7 8.3 8.9 0.36 11.1 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Sugar_tr PF00083.24 CCH57924.1 - 1.6e-155 518.4 28.3 1.8e-155 518.3 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH57924.1 - 5.1e-33 114.5 26.7 1.1e-30 106.8 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH57924.1 - 1.2e-06 27.3 1.5 1.2e-06 27.3 1.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 CCH57924.1 - 0.24 11.7 6.4 0.47 10.8 0.2 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) MFS_3 PF05977.13 CCH57924.1 - 0.25 9.7 5.7 0.086 11.2 1.9 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Flavi_NS4A PF01350.17 CCH57924.1 - 1.8 8.5 4.5 12 5.8 2.7 2.6 2 1 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2530 PF10745.9 CCH57924.1 - 4.7 7.5 9.9 0.32 11.3 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Clat_adaptor_s PF01217.20 CCH57925.1 - 6.2e-55 185.0 3.4 7.3e-55 184.8 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.16 CCH57926.1 - 5.7e-23 81.4 49.7 4e-20 72.1 30.2 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH57926.1 - 4.2e-05 22.6 32.0 0.00027 19.9 11.0 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFA1_2 PF17317.2 CCH57927.1 - 3.3e-24 84.3 0.4 3.5e-24 84.2 0.4 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 UQ_con PF00179.26 CCH57928.1 - 4.6e-39 133.3 0.1 5.9e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Vfa1 PF08432.10 CCH57928.1 - 0.12 12.7 7.2 0.16 12.3 7.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 CCH57928.1 - 0.13 11.6 13.6 0.16 11.3 13.6 1.2 1 0 0 1 1 1 0 BUD22 DUF3245 PF11595.8 CCH57928.1 - 0.15 12.5 7.6 0.26 11.7 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) RXT2_N PF08595.11 CCH57928.1 - 0.3 11.1 9.4 0.45 10.5 9.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 CCH57928.1 - 1.7 8.3 8.7 2.5 7.8 8.7 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CCH57928.1 - 3.7 6.8 19.8 5.4 6.2 19.8 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 CCH57928.1 - 7.6 6.3 13.4 10 5.8 13.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GCIP PF13324.6 CCH57928.1 - 8.7 5.9 10.5 13 5.3 10.5 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4976 PF16347.5 CCH57929.1 - 0.048 13.9 3.6 0.076 13.3 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) LSM PF01423.22 CCH57930.1 - 8.5e-11 41.4 0.1 1.1e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain TENA_THI-4 PF03070.16 CCH57931.1 - 5.9e-08 32.8 3.0 8.9e-08 32.2 3.0 1.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Arm PF00514.23 CCH57932.1 - 1.4e-69 228.2 30.7 2.2e-11 43.4 0.0 11.2 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CCH57932.1 - 1.3e-19 70.2 13.7 0.00021 21.7 0.2 7.7 5 2 2 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 CCH57932.1 - 1.5e-14 54.1 9.8 0.0037 17.6 0.1 7.4 4 2 4 8 8 8 4 HEAT repeats KAP PF05804.12 CCH57932.1 - 1.8e-11 42.9 0.2 4.4e-11 41.7 0.2 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT PF02985.22 CCH57932.1 - 1.7e-10 40.2 25.9 0.065 13.5 0.2 9.9 11 0 0 11 11 10 3 HEAT repeat Arm_2 PF04826.13 CCH57932.1 - 1.1e-09 38.1 6.9 6e-07 29.2 2.6 2.9 2 1 0 3 3 3 2 Armadillo-like Adaptin_N PF01602.20 CCH57932.1 - 1.3e-09 37.1 11.9 5.2e-07 28.6 2.1 3.2 1 1 1 2 2 2 2 Adaptin N terminal region DUF3361 PF11841.8 CCH57932.1 - 2.5e-06 27.5 2.9 0.0073 16.3 0.1 4.0 1 1 1 3 3 3 1 Domain of unknown function (DUF3361) Cnd1 PF12717.7 CCH57932.1 - 4e-06 27.0 8.6 0.13 12.3 0.2 5.3 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 CCH57932.1 - 1.3e-05 24.6 2.6 0.0024 17.2 0.6 3.4 1 1 1 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CCH57932.1 - 5.2e-05 23.3 4.7 0.098 12.8 0.1 5.1 3 2 5 8 8 8 1 V-ATPase subunit H Tti2 PF10521.9 CCH57932.1 - 9.6e-05 22.0 0.1 0.041 13.4 0.0 3.2 3 0 0 3 3 3 1 Tti2 family Vac14_Fab1_bd PF12755.7 CCH57932.1 - 0.00029 21.4 0.1 0.42 11.3 0.0 3.5 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.9 CCH57932.1 - 0.0029 16.2 2.7 0.42 9.1 0.1 3.6 3 2 1 4 4 4 2 Proteasome non-ATPase 26S subunit YqfD PF06898.11 CCH57932.1 - 0.043 12.7 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD YjeF_N PF03853.15 CCH57933.1 - 3.3e-27 95.5 0.0 6.4e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CCH57933.1 - 2.3e-09 38.1 15.4 2.3e-09 38.1 15.4 3.4 2 1 0 2 2 2 1 FDF domain TrkH PF02386.16 CCH57933.1 - 0.09 11.2 0.2 0.17 10.3 0.0 1.5 2 0 0 2 2 2 0 Cation transport protein Ras PF00071.22 CCH57934.1 - 1e-22 80.5 0.5 1.9e-12 47.1 0.4 3.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CCH57934.1 - 3.2e-05 24.1 0.1 0.0026 17.9 0.0 3.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCH57934.1 - 0.0038 17.3 0.9 0.033 14.3 0.4 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Phosphodiest PF01663.22 CCH57935.1 - 2e-41 142.8 0.7 3.8e-41 141.9 0.7 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PMP1_2 PF08114.11 CCH57936.1 - 6e-15 54.7 1.2 6.3e-15 54.6 1.2 1.0 1 0 0 1 1 1 1 ATPase proteolipid family Smim3 PF17307.2 CCH57936.1 - 0.11 12.0 1.4 0.13 11.8 1.4 1.1 1 0 0 1 1 1 0 Small integral membrane protein 3 FeoB_associated PF12669.7 CCH57936.1 - 0.76 10.2 4.8 1.4 9.4 4.8 1.5 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DNA_primase_S PF01896.19 CCH57937.1 - 0.01 15.9 0.9 0.015 15.4 0.9 1.4 1 0 0 1 1 1 0 DNA primase small subunit DUF2461 PF09365.10 CCH57937.1 - 0.029 14.3 0.9 0.063 13.2 0.9 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) zf-Nse PF11789.8 CCH57938.1 - 5.4e-19 67.8 1.6 1.1e-18 66.8 0.2 2.2 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCH57938.1 - 7.4e-05 22.7 0.6 0.0002 21.3 0.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DUF1741 PF08427.10 CCH57938.1 - 0.02 14.6 0.9 0.052 13.2 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1741) baeRF_family5 PF18846.1 CCH57938.1 - 0.093 12.9 0.7 0.15 12.3 0.3 1.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 zf-C3HC4_2 PF13923.6 CCH57938.1 - 0.1 12.5 2.7 0.092 12.6 1.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 CCH57938.1 - 0.1 12.3 1.9 0.14 11.9 0.6 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger tRNA-synt_2 PF00152.20 CCH57939.1 - 6.4e-82 275.1 0.0 9e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCH57939.1 - 6.7e-07 29.2 0.0 3.4e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCH57939.1 - 0.00062 19.3 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pox_MCEL PF03291.16 CCH57939.1 - 0.039 13.1 1.2 4.9 6.2 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme tRNA-synt_2b PF00587.25 CCH57939.1 - 0.04 13.9 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF3772 PF12607.8 CCH57939.1 - 0.093 12.5 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) Siah-Interact_N PF09032.11 CCH57939.1 - 0.31 11.4 1.4 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal MFS_1 PF07690.16 CCH57940.1 - 2.4e-28 99.1 9.9 9.1e-28 97.2 9.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CCH57940.1 - 0.0015 17.1 0.4 0.0015 17.1 0.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5521 PF17659.1 CCH57940.1 - 0.094 10.5 0.0 0.15 9.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) MFS_1 PF07690.16 CCH57941.1 - 3.2e-28 98.7 15.4 1.2e-27 96.8 15.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH57941.1 - 1.5e-07 30.7 6.8 1.5e-07 30.7 6.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter Hol_Tox PF16935.5 CCH57941.1 - 0.043 13.9 0.1 0.4 10.8 0.3 2.5 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) zf-Tim10_DDP PF02953.15 CCH57942.1 - 1.8e-20 72.3 5.7 1.8e-20 72.3 5.7 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 CCH57942.1 - 0.012 15.8 0.1 0.15 12.3 0.1 2.0 1 1 1 2 2 2 0 Phasin protein Hormone_recep PF00104.30 CCH57942.1 - 0.028 14.0 2.0 0.033 13.8 2.0 1.1 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Tam41_Mmp37 PF09139.11 CCH57942.1 - 0.04 13.4 0.6 0.043 13.2 0.6 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Aminotran_1_2 PF00155.21 CCH57943.1 - 8.6e-65 219.3 0.0 1.1e-64 219.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CCH57943.1 - 2.7e-07 29.5 0.0 4.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CCH57943.1 - 0.00023 20.6 0.0 0.00075 18.9 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CCH57943.1 - 0.0051 15.8 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCH57943.1 - 0.045 13.1 0.4 0.55 9.5 0.4 2.2 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Reticulon PF02453.17 CCH57944.1 - 1.7e-34 119.1 4.6 2.2e-34 118.7 4.6 1.2 1 0 0 1 1 1 1 Reticulon DUF2547 PF10818.8 CCH57944.1 - 0.11 13.4 0.0 0.21 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) TMEM138 PF14935.6 CCH57944.1 - 0.56 10.9 7.6 4.5 7.9 2.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 138 Aconitase PF00330.20 CCH57945.1 - 2.1e-110 369.9 0.0 6e-109 365.1 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCH57945.1 - 9.7e-25 87.4 0.0 1.9e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Porphobil_deam PF01379.20 CCH57946.1 - 9.5e-72 240.8 0.0 1.3e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CCH57946.1 - 1.1e-17 64.1 1.0 2.1e-17 63.3 1.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CSN7a_helixI PF18392.1 CCH57946.1 - 0.057 13.3 0.2 0.057 13.3 0.2 2.2 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain ANAPC4_WD40 PF12894.7 CCH57947.1 - 4.4e-10 39.7 0.9 0.48 10.8 0.0 5.0 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH57947.1 - 6.7e-10 39.4 12.6 0.0023 18.7 0.8 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.11 CCH57947.1 - 0.035 14.0 0.4 0.16 11.8 0.1 2.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DASH_Dad3 PF08656.10 CCH57948.1 - 6.2e-18 64.7 8.9 1.3e-17 63.6 8.9 1.5 1 1 0 1 1 1 1 DASH complex subunit Dad3 TALPID3 PF15324.6 CCH57948.1 - 0.0046 14.7 0.9 0.0051 14.6 0.9 1.0 1 0 0 1 1 1 1 Hedgehog signalling target TAF6_C PF07571.13 CCH57949.1 - 8.4e-32 109.4 0.0 2.4e-31 107.9 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CCH57949.1 - 5.1e-25 87.4 0.1 9.6e-25 86.6 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 CCH57949.1 - 0.0021 18.1 0.1 0.0063 16.6 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CCH57949.1 - 0.0042 17.5 5.9 0.24 11.8 0.1 3.1 3 0 0 3 3 3 2 Core histone H2A/H2B/H3/H4 BAT2_N PF07001.11 CCH57949.1 - 2.6 8.5 10.1 2 8.9 5.1 2.4 3 0 0 3 3 3 0 BAT2 N-terminus SLD3 PF08639.10 CCH57950.1 - 2.5e-35 122.3 29.5 3.3e-28 98.8 22.9 2.2 1 1 1 2 2 2 2 DNA replication regulator SLD3 Sld3_N PF18523.1 CCH57950.1 - 3.1e-05 24.0 1.5 0.00017 21.6 1.5 2.4 1 0 0 1 1 1 1 Sld3 N-terminal domain BCNT PF07572.12 CCH57951.1 - 1.8e-24 85.6 0.3 1.8e-24 85.6 0.3 2.9 2 1 1 3 3 3 1 Bucentaur or craniofacial development CBS PF00571.28 CCH57952.1 - 3e-27 94.8 1.7 1.8e-10 41.1 0.0 4.3 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.11 CCH57952.1 - 0.12 12.5 0.7 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ANAPC4_WD40 PF12894.7 CCH57953.1 - 1.3e-13 51.1 3.2 0.00012 22.4 0.3 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH57953.1 - 4.6e-13 49.4 13.8 0.00024 21.8 0.7 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCH57953.1 - 4.9e-08 32.3 0.2 2e-05 23.7 0.1 3.2 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FcoT PF10862.8 CCH57953.1 - 0.036 13.7 0.1 0.32 10.6 0.0 2.6 3 0 0 3 3 3 0 FcoT-like thioesterase domain CLTH PF10607.9 CCH57954.1 - 1.4e-08 34.7 7.6 1.4e-08 34.7 7.6 2.1 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CCH57954.1 - 1.1e-06 28.5 3.2 3.1e-06 27.1 3.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCH57954.1 - 9.6e-05 22.5 1.2 0.00026 21.1 1.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CCH57954.1 - 0.00025 20.9 3.1 0.00056 19.8 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CCH57954.1 - 0.00071 19.9 3.7 0.0016 18.8 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CCH57954.1 - 0.0038 17.1 2.1 0.0088 15.9 2.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CCH57954.1 - 0.0095 15.8 4.6 0.023 14.5 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acyltransf_C PF16076.5 CCH57954.1 - 0.026 14.6 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 Acyltransferase C-terminus zf-C3HC4_3 PF13920.6 CCH57954.1 - 0.046 13.6 2.0 0.093 12.6 2.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 CCH57954.1 - 0.15 11.8 2.0 0.31 10.8 2.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.6 CCH57954.1 - 0.16 11.8 4.5 0.38 10.6 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-N PF05238.13 CCH57955.1 - 1.3e-93 314.5 0.1 2.2e-93 313.8 0.1 1.3 1 1 0 1 1 1 1 Kinetochore protein CHL4 like RRM_1 PF00076.22 CCH57956.1 - 2.9e-54 180.8 0.6 2.8e-17 62.3 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH57956.1 - 2.4e-07 30.8 0.4 0.015 15.4 0.0 4.2 4 1 1 5 5 5 2 RNA recognition motif Pkinase PF00069.25 CCH57957.1 - 6.3e-57 192.9 0.0 6.3e-57 192.9 0.0 3.4 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH57957.1 - 2e-26 92.8 0.1 4e-25 88.6 0.1 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CCH57957.1 - 0.82 9.5 0.0 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Epimerase PF01370.21 CCH57958.1 - 1.2e-19 70.7 0.1 5.6e-19 68.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCH57958.1 - 2e-11 43.9 1.6 6.8e-11 42.1 1.6 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CCH57958.1 - 2.3e-11 43.3 0.1 3.1e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCH57958.1 - 2.5e-09 36.7 0.2 1.2e-07 31.2 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CCH57958.1 - 2.1e-07 30.4 0.9 9.8e-07 28.2 0.1 2.2 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CCH57958.1 - 2.7e-06 27.4 0.0 9.1e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CCH57958.1 - 1e-05 25.1 0.2 2.7e-05 23.7 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CCH57958.1 - 4.2e-05 23.5 0.0 7.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 CCH57958.1 - 0.0012 18.5 0.0 0.0039 16.8 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 CCH57958.1 - 0.0028 16.8 0.0 0.0081 15.3 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Shikimate_DH PF01488.20 CCH57958.1 - 0.018 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 CCH57958.1 - 0.047 13.8 0.0 0.38 10.9 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.6 CCH57958.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase tRNA-synt_1 PF00133.22 CCH57959.1 - 2.4e-151 505.0 1.1 3.2e-151 504.6 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCH57959.1 - 3e-20 72.7 2.2 1.1e-19 70.9 2.2 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCH57959.1 - 1.4e-19 70.1 0.2 2e-10 40.0 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCH57959.1 - 0.036 13.6 0.0 0.12 11.9 0.0 1.9 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 zf-UDP PF14569.6 CCH57959.1 - 0.078 13.1 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-FPG_IleRS PF06827.14 CCH57959.1 - 8.1 6.4 6.9 37 4.3 7.2 1.9 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS zf-C2H2 PF00096.26 CCH57960.1 - 1.2e-10 41.3 9.4 9.1e-06 25.8 1.0 2.8 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH57960.1 - 9e-09 35.4 5.0 0.0011 19.6 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCH57960.1 - 9.4e-05 22.3 3.9 0.21 11.7 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CCH57960.1 - 0.0001 22.0 4.5 0.042 13.6 0.1 3.0 2 1 1 3 3 3 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CCH57960.1 - 0.00014 22.2 5.0 0.00035 20.9 0.4 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zinc_ribbon_15 PF17032.5 CCH57960.1 - 0.0066 17.2 1.5 0.0066 17.2 1.5 1.7 1 1 0 1 1 1 1 zinc-ribbon family zf_C2H2_13 PF18508.1 CCH57960.1 - 0.0076 15.8 1.2 0.95 9.1 0.1 3.0 3 0 0 3 3 3 1 Zinc finger domain zf-C2H2_3 PF13878.6 CCH57960.1 - 0.046 13.5 1.7 0.046 13.5 1.7 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_jaz PF12171.8 CCH57960.1 - 0.072 13.4 8.1 0.69 10.3 0.9 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CCH57960.1 - 0.23 11.5 5.0 0.94 9.6 0.3 2.5 2 0 0 2 2 2 0 BED zinc finger C1_4 PF07975.12 CCH57960.1 - 0.35 11.1 3.9 0.45 10.8 0.5 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_ribbon_SprT PF17283.2 CCH57960.1 - 0.38 10.7 3.3 0.94 9.4 0.6 2.2 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-met PF12874.7 CCH57960.1 - 0.39 11.2 4.4 1.5 9.3 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CCH57960.1 - 0.4 10.6 2.2 3.3 7.7 0.4 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 CCH57960.1 - 0.41 11.1 6.3 2.6 8.6 0.9 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 CCH57960.1 - 0.43 10.2 1.9 12 5.6 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 CCH57960.1 - 0.59 10.1 4.1 1 9.3 0.4 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 CCH57960.1 - 1.1 9.4 5.3 2.9 8.1 3.1 2.3 1 1 1 2 2 2 0 Zinc ribbon domain RIG-I_C-RD PF11648.8 CCH57960.1 - 1.4 9.2 7.1 0.61 10.3 4.4 1.8 2 0 0 2 2 2 0 C-terminal domain of RIG-I LIM PF00412.22 CCH57960.1 - 3.2 8.0 6.5 42 4.5 6.9 2.3 1 1 0 1 1 1 0 LIM domain Pkinase PF00069.25 CCH57963.1 - 2.5e-74 250.0 0.0 2.6e-73 246.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH57963.1 - 6.6e-36 123.9 0.0 9.5e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH57963.1 - 0.00038 19.9 0.1 0.001 18.5 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CCH57963.1 - 0.0016 17.5 0.1 0.006 15.6 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCH57963.1 - 0.0091 15.9 0.0 0.069 13.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Thiolase_N PF00108.23 CCH57964.1 - 3.6e-98 328.1 2.1 4.4e-98 327.8 2.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCH57964.1 - 6.7e-43 145.2 0.7 1.4e-42 144.2 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCH57964.1 - 0.0084 15.7 0.4 0.022 14.3 0.4 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CCH57964.1 - 0.03 14.2 0.7 1.2 9.0 0.5 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AAA_18 PF13238.6 CCH57965.1 - 3.2e-07 31.0 0.1 5.5e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CCH57965.1 - 1.3e-05 25.2 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 CCH57965.1 - 2.6e-05 24.7 0.1 3.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CCH57965.1 - 7.7e-05 22.5 0.0 0.00038 20.2 0.0 1.9 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CCH57965.1 - 8.4e-05 22.8 0.0 0.0005 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CCH57965.1 - 0.00043 20.4 0.1 0.0013 18.8 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 CCH57965.1 - 0.00097 19.1 0.9 0.0022 18.0 0.3 1.7 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Cytidylate_kin PF02224.18 CCH57965.1 - 0.0048 16.7 0.0 0.0071 16.1 0.0 1.5 1 1 0 1 1 1 1 Cytidylate kinase DnaB_C PF03796.15 CCH57965.1 - 0.0052 16.2 0.2 0.78 9.0 0.0 2.2 1 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CCH57965.1 - 0.0059 16.9 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH57965.1 - 0.0098 16.3 0.0 0.017 15.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CCH57965.1 - 0.012 14.7 0.0 0.032 13.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 CCH57965.1 - 0.023 14.7 0.0 0.065 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mt_ATP-synt_D PF05873.12 CCH57965.1 - 0.025 14.4 0.3 0.61 9.9 0.1 2.2 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) KTI12 PF08433.10 CCH57965.1 - 0.028 13.9 0.0 0.041 13.3 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 CCH57965.1 - 0.031 14.5 0.0 0.092 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCH57965.1 - 0.035 13.6 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CCH57965.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CCH57965.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCH57965.1 - 0.079 13.4 0.1 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Pkinase PF00069.25 CCH57966.1 - 2.7e-46 158.1 0.8 4.2e-40 137.8 0.2 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH57966.1 - 1e-19 70.9 0.0 1.6e-17 63.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCH57966.1 - 6.2e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like ARID PF01388.21 CCH57967.1 - 3.4e-15 56.5 0.3 3.4e-15 56.5 0.3 4.2 6 0 0 6 6 6 1 ARID/BRIGHT DNA binding domain Glyco_transf_34 PF05637.12 CCH57968.1 - 5.6e-75 252.1 0.9 7.1e-75 251.8 0.9 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CCH57968.1 - 0.0033 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_tranf_2_4 PF13704.6 CCH57968.1 - 0.051 14.1 0.2 0.47 11.0 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 2 TPR_1 PF00515.28 CCH57969.1 - 9e-18 63.3 2.3 2.5e-05 23.9 0.0 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH57969.1 - 1.4e-15 56.6 0.3 5.7e-05 22.7 0.0 5.5 4 1 2 6 6 6 3 TPR repeat TPR_2 PF07719.17 CCH57969.1 - 1.6e-15 55.9 0.4 0.00059 19.8 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCH57969.1 - 5.2e-13 48.6 0.1 0.0061 17.3 0.2 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH57969.1 - 5.1e-12 45.0 1.8 0.021 15.0 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCH57969.1 - 9e-11 42.1 0.9 0.031 14.8 0.0 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCH57969.1 - 1.1e-10 42.0 0.2 0.00016 22.3 0.3 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCH57969.1 - 4.8e-10 39.1 7.9 0.056 13.8 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 CCH57969.1 - 3.7e-08 33.4 0.0 0.00031 20.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CCH57969.1 - 1.7e-07 31.4 1.6 0.26 11.6 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH57969.1 - 0.00043 20.5 2.1 0.098 13.0 0.5 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCH57969.1 - 0.0018 18.8 0.1 33 5.4 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH57969.1 - 0.0031 17.4 0.0 4.2 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCH57969.1 - 0.0091 15.2 0.1 0.097 11.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH57969.1 - 0.036 14.3 2.1 0.62 10.3 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CCH57969.1 - 0.059 13.8 0.1 0.34 11.3 0.0 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 CCH57969.1 - 0.7 9.8 7.0 2.8 7.9 0.5 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 CCH57970.1 - 1.1e-25 89.2 0.2 2e-25 88.3 0.1 1.5 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adaptin_N PF01602.20 CCH57971.1 - 2.3e-107 359.7 13.3 3.9e-107 359.0 13.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CCH57971.1 - 2.8e-54 182.8 0.3 2.8e-54 182.8 0.3 2.2 3 0 0 3 3 3 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CCH57971.1 - 2.9e-53 179.2 0.1 1.3e-52 177.1 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 CCH57971.1 - 1.7e-07 31.4 0.4 1.7e-07 31.4 0.4 3.6 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCH57971.1 - 6.5e-07 29.7 0.8 0.0035 17.7 0.0 4.5 2 1 0 3 3 3 1 HEAT repeats Alpha_adaptinC2 PF02883.20 CCH57971.1 - 0.0021 18.4 0.1 0.005 17.1 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF5578 PF17741.1 CCH57971.1 - 0.035 13.5 5.6 0.67 9.3 0.1 3.3 3 1 1 4 4 4 0 Family of unknown function (DUF5578) FANCI_S2 PF14676.6 CCH57971.1 - 0.16 12.3 4.9 0.091 13.1 0.4 2.7 3 0 0 3 3 3 0 FANCI solenoid 2 HEAT PF02985.22 CCH57971.1 - 0.16 12.3 0.4 9.6 6.8 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat AP4E_app_platf PF14807.6 CCH57971.1 - 0.17 12.3 0.6 1.4 9.3 0.0 2.8 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform GLE1 PF07817.13 CCH57972.1 - 8.8e-88 293.7 0.5 1.4e-87 293.1 0.5 1.3 1 0 0 1 1 1 1 GLE1-like protein YvrJ PF12841.7 CCH57972.1 - 0.039 13.5 0.4 3.6 7.2 0.0 2.6 2 0 0 2 2 2 0 YvrJ protein family Na_Ca_ex PF01699.24 CCH57973.1 - 8.5e-49 165.4 30.5 1e-27 97.0 8.2 3.8 4 1 0 4 4 4 2 Sodium/calcium exchanger protein Myb_DNA-bind_7 PF15963.5 CCH57973.1 - 0.096 12.6 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Myb DNA-binding like MFA1_2 PF17317.2 CCH57975.1 - 7.5e-21 73.6 0.7 8e-21 73.5 0.7 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 OPT PF03169.15 CCH57976.1 - 4e-124 415.5 32.8 4.9e-124 415.2 32.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AA_permease PF00324.21 CCH57977.1 - 3.4e-51 174.3 42.2 4.4e-51 174.0 42.2 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CCH57977.1 - 4.6e-14 52.3 6.3 2.2e-07 30.3 0.2 3.2 3 0 0 3 3 3 3 Solute carrier family 12 AA_permease_2 PF13520.6 CCH57977.1 - 2.1e-12 46.6 44.5 4.1e-12 45.7 44.5 1.4 1 0 0 1 1 1 1 Amino acid permease EF-hand_7 PF13499.6 CCH57979.1 - 9.3e-11 42.0 3.4 2.8e-08 34.1 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCH57979.1 - 1.8e-08 33.4 4.1 0.00079 18.8 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CCH57979.1 - 4e-08 32.5 7.0 0.0003 20.5 0.1 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 CCH57979.1 - 8.6e-08 32.4 0.1 0.0035 17.6 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 CCH57979.1 - 3.5e-07 30.0 2.0 3.7e-05 23.5 0.1 3.1 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_11 PF08976.11 CCH57979.1 - 0.002 19.0 0.0 0.0033 18.3 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain EF-hand_14 PF17959.1 CCH57979.1 - 0.0063 16.8 0.3 1.7 9.1 0.0 2.6 1 1 2 3 3 3 2 EF-hand domain ExbD PF02472.16 CCH57979.1 - 0.074 13.2 0.5 0.3 11.3 0.5 1.8 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR HD_3 PF13023.6 CCH57980.1 - 3.4e-38 131.2 1.6 4.3e-38 130.8 1.6 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CCH57980.1 - 9.5e-10 38.5 1.4 1.5e-09 37.9 1.4 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CCH57980.1 - 9.7e-06 25.8 0.1 4.2e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 HD domain WD40 PF00400.32 CCH57981.1 - 0.003 18.4 5.6 18 6.4 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 CCH57981.1 - 0.19 12.3 0.3 1.7e+02 2.9 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain RCC1 PF00415.18 CCH57982.1 - 6.3e-59 196.4 0.1 4.5e-08 33.6 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCH57982.1 - 4.2e-37 125.2 20.8 1.3e-07 31.2 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DAHP_synth_1 PF00793.20 CCH57983.1 - 1.9e-108 361.5 0.0 2.2e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RRM_1 PF00076.22 CCH57984.1 - 1.4e-14 53.6 0.1 2.2e-14 53.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 CCH57985.1 - 2.8e-11 43.1 6.8 5.5e-11 42.2 6.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 CCH57985.1 - 0.14 12.0 1.3 0.33 10.8 1.3 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PHD_2 PF13831.6 CCH57985.1 - 0.61 9.7 5.2 1.1 8.9 5.2 1.4 1 0 0 1 1 1 0 PHD-finger Sec1 PF00995.23 CCH57986.1 - 3.3e-116 389.8 25.0 3.7e-116 389.6 25.0 1.0 1 0 0 1 1 1 1 Sec1 family TCO89 PF10452.9 CCH57987.1 - 1.2e-89 302.0 88.5 3.3e-61 208.0 49.4 2.2 1 1 1 2 2 2 2 TORC1 subunit TCO89 WD40 PF00400.32 CCH57988.1 - 2.3e-19 69.4 12.3 4.4e-07 30.5 0.1 7.7 7 0 0 7 7 7 4 WD domain, G-beta repeat YmzC PF14157.6 CCH57988.1 - 0.1 12.7 1.8 0.59 10.3 0.1 3.3 3 0 0 3 3 3 0 YmzC-like protein Kelch_6 PF13964.6 CCH57988.1 - 0.9 9.9 4.9 1.3e+02 3.1 0.0 5.2 5 0 0 5 5 5 0 Kelch motif Pallilysin PF18663.1 CCH57988.1 - 1.7 8.6 6.2 5.7 7.0 0.2 3.5 4 0 0 4 4 4 0 Pallilysin beta barrel domain Nucleoporin2 PF04096.14 CCH57989.1 - 8.5e-46 155.8 0.0 2.3e-45 154.3 0.0 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 CCH57989.1 - 1.1e-33 116.6 0.4 1.7e-31 109.5 0.4 2.5 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 CCH57989.1 - 9e-16 58.5 94.9 8.8e-10 39.3 29.6 5.0 3 1 2 5 5 5 3 Nucleoporin FG repeat region Galanin PF01296.18 CCH57989.1 - 0.18 11.8 0.7 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Galanin ParA PF10609.9 CCH57990.1 - 3.2e-94 315.0 0.0 3.8e-94 314.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCH57990.1 - 4.1e-09 36.6 0.0 3.1e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCH57990.1 - 4.6e-07 29.9 0.5 6.1e-06 26.3 0.5 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CCH57990.1 - 1.1e-05 24.8 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CCH57990.1 - 4.2e-05 22.9 0.3 0.0029 16.9 0.0 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 CCH57990.1 - 0.0079 16.1 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase CBP_BcsQ PF06564.12 CCH57990.1 - 0.044 13.3 0.1 0.074 12.5 0.1 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_15 PF13175.6 CCH57990.1 - 0.065 12.9 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.6 CCH57990.1 - 0.066 13.0 0.0 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CCH57990.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 CCH57990.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CCH57990.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain UQ_con PF00179.26 CCH57991.1 - 8.8e-17 61.1 0.0 1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCH57991.1 - 0.0099 16.2 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain COA2 PF17051.5 CCH57992.1 - 1e-14 54.4 0.2 1.2e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 PDE4_UCR PF18100.1 CCH57993.1 - 1.4 9.6 5.0 1.9 9.2 1.5 2.5 1 1 1 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) MPC PF03650.13 CCH57994.1 - 4.9e-40 136.1 0.0 6.1e-40 135.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Rad9 PF04139.13 CCH57995.1 - 4.1e-12 46.1 5.2 1.1e-10 41.4 5.2 2.2 1 1 0 1 1 1 1 Rad9 TLD PF07534.16 CCH57996.1 - 2e-29 102.6 0.3 1e-27 97.0 0.3 2.2 1 1 0 1 1 1 1 TLD AA_permease_2 PF13520.6 CCH57997.1 - 9.1e-52 176.3 45.9 1.1e-51 176.1 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCH57997.1 - 2.1e-21 76.1 35.1 2.7e-21 75.7 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2678 PF10856.8 CCH57997.1 - 1.6 8.6 8.9 0.081 12.9 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) Ribosomal_L30_N PF08079.12 CCH57998.1 - 2.7e-22 78.8 17.4 4.3e-22 78.1 17.4 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CCH57998.1 - 3.4e-18 65.2 2.0 7.5e-18 64.2 2.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Lipoprotein_7 PF01540.16 CCH57998.1 - 0.043 13.1 2.9 0.075 12.3 2.9 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein CSRNP_N PF16019.5 CCH57998.1 - 0.25 11.2 0.9 0.32 10.9 0.9 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pinin_SDK_memA PF04696.13 CCH57998.1 - 0.48 10.5 7.8 0.74 9.9 7.8 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF1771 PF08590.10 CCH57999.1 - 1e-16 61.1 9.3 1e-16 61.1 9.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 CCH57999.1 - 1.1e-11 44.9 0.8 2.1e-11 44.0 0.2 1.8 2 0 0 2 2 2 1 Smr domain DUF4915 PF16261.5 CCH57999.1 - 0.022 14.0 0.3 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4915) Pex14_N PF04695.13 CCH57999.1 - 0.64 10.7 13.1 0.15 12.7 6.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 CCH57999.1 - 3.5 7.9 6.9 0.94 9.7 0.5 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CYSTM PF12734.7 CCH57999.1 - 4.5 7.7 27.7 1.6e+04 -3.7 27.7 2.6 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance MPS2 PF17060.5 CCH58000.1 - 4e-20 72.4 10.9 2e-11 43.8 0.2 2.2 1 1 1 2 2 2 2 Monopolar spindle protein 2 RST PF12174.8 CCH58000.1 - 0.079 12.9 0.5 1 9.4 0.2 2.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain HSF_DNA-bind PF00447.17 CCH58001.1 - 1.7e-31 108.7 3.3 3.9e-31 107.5 3.3 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Uds1 PF15456.6 CCH58001.1 - 0.13 12.4 4.3 0.2 11.8 2.2 2.3 2 0 0 2 2 2 0 Up-regulated During Septation IF-2B PF01008.17 CCH58001.1 - 0.22 10.7 1.8 0.55 9.4 1.8 1.6 1 0 0 1 1 1 0 Initiation factor 2 subunit family POX PF07526.11 CCH58001.1 - 0.23 12.0 8.3 0.083 13.5 3.5 2.4 2 0 0 2 2 2 0 Associated with HOX DUF1664 PF07889.12 CCH58001.1 - 0.81 9.7 3.3 25 4.9 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vfa1 PF08432.10 CCH58001.1 - 1.5 9.1 8.2 3.1 8.1 8.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLZ PF16526.5 CCH58001.1 - 1.9 8.9 9.6 1.8 9.0 0.4 3.3 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 CCH58001.1 - 1.9 8.3 9.2 3.5 7.5 0.1 2.7 2 1 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 CCH58001.1 - 9.3 6.8 10.4 2 8.9 5.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region AFT PF08731.11 CCH58003.1 - 9.4e-44 148.4 4.5 9.4e-44 148.4 4.5 3.6 4 0 0 4 4 4 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 CCH58003.1 - 0.26 11.3 3.0 17 5.5 0.3 2.6 2 0 0 2 2 2 0 MuDR family transposase Pkinase PF00069.25 CCH58004.1 - 6.7e-75 251.8 0.0 1.1e-74 251.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58004.1 - 4.1e-41 141.0 0.0 6.3e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58004.1 - 6.5e-06 25.7 0.0 1.6e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like A_deaminase_N PF08451.11 CCH58004.1 - 0.21 11.9 1.7 5 7.5 0.0 2.4 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal Pkinase PF00069.25 CCH58005.1 - 2.5e-24 86.1 0.3 5.6e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58005.1 - 2.7e-15 56.4 1.4 2.7e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH58005.1 - 1.7e-09 37.0 1.0 2.4e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCH58005.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ERp29_N PF07912.13 CCH58005.1 - 0.069 13.3 1.1 0.22 11.7 0.1 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain EF-hand_6 PF13405.6 CCH58005.1 - 0.073 13.0 0.5 0.64 10.1 0.3 2.5 2 0 0 2 2 2 0 EF-hand domain DUF4735 PF15882.5 CCH58005.1 - 3.8 6.9 10.1 0.39 10.1 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4735) Pkinase PF00069.25 CCH58006.1 - 1.1e-70 238.0 0.0 1.5e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58006.1 - 1.6e-43 148.9 0.0 2.2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58006.1 - 0.00011 21.6 0.0 0.001 18.5 0.1 2.3 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 CCH58006.1 - 0.0065 16.0 0.3 0.013 15.0 0.3 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 CCH58006.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCH58006.1 - 0.11 12.2 0.8 0.34 10.5 0.1 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DAP3 PF10236.9 CCH58007.1 - 2e-79 267.0 1.3 2.5e-79 266.7 1.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CCH58007.1 - 4.4e-06 27.2 0.0 1e-05 26.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH58007.1 - 4.8e-05 23.7 0.0 0.00024 21.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCH58007.1 - 0.036 14.1 0.2 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CCH58007.1 - 0.042 13.8 0.1 0.48 10.3 0.1 2.9 3 1 0 3 3 3 0 NACHT domain DUF2075 PF09848.9 CCH58007.1 - 0.054 12.7 0.1 0.097 11.9 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CCH58007.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CCH58007.1 - 0.073 13.0 0.0 0.32 10.9 0.0 2.1 2 1 0 2 2 2 0 NTPase AAA_29 PF13555.6 CCH58007.1 - 0.077 12.7 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCH58007.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MCM PF00493.23 CCH58007.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain DUF2791 PF10923.8 CCH58007.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) mRNA_cap_enzyme PF01331.19 CCH58008.1 - 3.5e-60 203.2 0.1 6.4e-60 202.3 0.0 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CCH58008.1 - 8.8e-34 116.4 0.7 1.6e-33 115.6 0.7 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CCH58008.1 - 9.7e-06 25.4 0.0 0.0046 16.6 0.0 2.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Ubiq_cyt_C_chap PF03981.12 CCH58009.1 - 2.4e-41 141.1 0.3 3.9e-41 140.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WAC_Acf1_DNA_bd PF10537.9 CCH58010.1 - 8.8e-36 122.5 2.1 8.8e-36 122.5 2.1 4.1 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CCH58010.1 - 4.2e-11 43.2 0.1 4.2e-11 43.2 0.1 7.0 5 3 0 5 5 5 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CCH58010.1 - 1e-10 41.8 3.3 1.6e-10 41.1 0.8 2.4 2 0 0 2 2 2 1 DDT domain Cyclin PF08613.11 CCH58011.1 - 1.6e-16 61.1 1.6 1.6e-16 61.1 1.6 2.1 2 1 0 2 2 2 1 Cyclin Ribosomal_L1 PF00687.21 CCH58012.1 - 2.3e-42 145.0 0.5 2.8e-42 144.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TRP PF06011.12 CCH58013.1 - 1e-151 505.5 35.7 1.7e-151 504.8 35.7 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCH58013.1 - 7.5e-39 133.3 0.1 1.4e-38 132.4 0.1 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CCH58013.1 - 0.002 18.6 0.1 0.0035 17.8 0.1 1.4 1 0 0 1 1 1 1 ML domain DUF4473 PF14747.6 CCH58013.1 - 0.16 12.5 1.1 0.31 11.6 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) TRP PF06011.12 CCH58014.1 - 4.2e-151 503.5 35.4 5.2e-151 503.2 35.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCH58014.1 - 2e-38 131.9 0.2 3.5e-38 131.1 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CCH58014.1 - 0.0037 17.7 0.1 0.0065 16.9 0.1 1.4 1 0 0 1 1 1 1 ML domain JmjC PF02373.22 CCH58016.1 - 8e-13 48.8 7.5 1.1e-06 29.1 0.2 3.6 2 1 0 3 3 3 2 JmjC domain, hydroxylase ARID PF01388.21 CCH58016.1 - 1.9e-07 31.7 0.4 1.2e-06 29.0 0.4 2.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 CCH58016.1 - 3.7e-07 29.9 10.1 6.9e-07 29.1 10.1 1.5 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 CCH58016.1 - 0.02 15.0 3.5 0.044 13.9 3.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 CCH58016.1 - 0.063 13.5 3.8 0.18 12.1 3.8 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 CCH58016.1 - 0.066 13.1 0.7 0.16 11.8 0.7 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 CCH58016.1 - 0.43 10.8 2.5 0.93 9.7 2.5 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Cation_efflux PF01545.21 CCH58017.1 - 4.7e-40 137.5 12.6 6.6e-40 137.0 12.6 1.2 1 0 0 1 1 1 1 Cation efflux family E1_FCCH PF16190.5 CCH58018.1 - 0.023 14.9 0.2 0.12 12.6 0.2 2.3 1 1 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain DUF2944 PF11161.8 CCH58018.1 - 0.035 14.0 0.8 0.099 12.5 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Glycos_transf_2 PF00535.26 CCH58019.1 - 5e-25 88.3 0.0 7.4e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCH58019.1 - 2.8e-08 33.9 0.0 4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CCH58019.1 - 0.00045 19.8 0.0 0.00063 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CCH58019.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 mRNA_triPase PF02940.15 CCH58020.1 - 1.3e-64 217.9 5.0 1.3e-64 217.9 5.0 2.6 3 0 0 3 3 3 1 mRNA capping enzyme, beta chain DUF1758 PF05585.12 CCH58020.1 - 0.14 12.0 3.5 5.2 6.8 0.3 2.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Mis14 PF08641.12 CCH58021.1 - 1.4e-25 90.1 1.4 2.2e-25 89.5 1.4 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like DUF5638 PF18688.1 CCH58021.1 - 0.098 13.0 1.9 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5638) GTP_EFTU_D3 PF03143.17 CCH58021.1 - 0.14 12.4 0.0 6.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain ATP-synt_C PF00137.21 CCH58022.1 - 1.1e-32 112.1 32.9 6.8e-19 68.0 9.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TIP49 PF06068.13 CCH58023.1 - 9.2e-158 525.0 1.9 1.2e-157 524.7 1.9 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCH58023.1 - 1e-24 86.4 0.9 3.4e-24 84.8 0.7 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CCH58023.1 - 7.8e-09 36.0 0.6 1.6e-05 25.3 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCH58023.1 - 2.6e-07 30.5 0.6 0.0014 18.3 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CCH58023.1 - 2.4e-05 23.8 0.2 4.7e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CCH58023.1 - 3.6e-05 24.2 0.2 0.00014 22.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH58023.1 - 0.0015 18.8 0.1 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCH58023.1 - 0.0021 18.4 0.4 0.015 15.6 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CCH58023.1 - 0.013 15.5 0.2 2.2 8.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CCH58023.1 - 0.027 14.0 0.3 0.069 12.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCH58023.1 - 0.03 13.7 0.6 0.6 9.5 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCH58023.1 - 0.064 13.0 0.0 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 CCH58023.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCH58023.1 - 0.24 10.9 1.0 0.72 9.3 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region Pkinase PF00069.25 CCH58024.1 - 1.3e-32 113.2 0.0 2e-23 83.1 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58024.1 - 7.7e-16 58.1 0.0 6.8e-12 45.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase eIF-5_eIF-2B PF01873.17 CCH58026.1 - 1.5e-38 131.2 2.8 7.3e-38 129.1 0.2 2.5 3 0 0 3 3 3 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 CCH58026.1 - 0.028 13.9 0.2 0.072 12.6 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 CCH58026.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) RR_TM4-6 PF06459.12 CCH58026.1 - 1.7 8.4 11.6 2.5 7.9 11.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arc_trans_TRASH PF08394.10 CCH58026.1 - 3.4 8.1 6.2 32 5.0 2.4 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain RasGAP_C PF03836.15 CCH58027.1 - 6.2e-25 87.9 2.3 6.2e-25 87.9 2.3 3.2 5 0 0 5 5 5 1 RasGAP C-terminus RasGAP PF00616.19 CCH58027.1 - 5.7e-18 65.4 4.7 5.7e-18 65.4 4.7 3.5 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 CCH58027.1 - 1e-11 45.0 0.1 4.1e-11 43.0 0.1 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 CCH58027.1 - 2.9e-06 26.6 29.4 0.0035 17.0 0.3 9.1 10 0 0 10 10 10 2 IQ calmodulin-binding motif DUF2833 PF11090.8 CCH58027.1 - 0.11 12.8 0.3 0.76 10.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) BUD22 PF09073.10 CCH58027.1 - 8.4 5.6 35.5 0.0099 15.3 23.3 2.1 2 0 0 2 2 2 0 BUD22 RINGv PF12906.7 CCH58028.1 - 0.00091 19.3 8.1 0.0018 18.4 8.1 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 CCH58028.1 - 0.2 11.8 8.8 6.8 7.0 0.1 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CCH58028.1 - 9.7 6.6 17.7 0.21 12.0 8.5 2.6 2 1 1 3 3 3 0 Ring finger domain SRP68 PF16969.5 CCH58029.1 - 1.4e-62 212.5 17.3 1.7e-62 212.2 17.3 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF2075 PF09848.9 CCH58030.1 - 1.4e-107 360.1 0.0 2.1e-107 359.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CCH58030.1 - 1.3e-07 32.0 0.0 3.8e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH58030.1 - 0.0001 22.7 0.0 0.00026 21.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CCH58030.1 - 0.00017 22.0 0.0 0.00037 20.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCH58030.1 - 0.00056 19.7 0.0 0.0031 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 CCH58030.1 - 0.006 16.8 1.0 27 5.0 0.1 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 CCH58030.1 - 0.0098 15.9 0.3 0.15 12.0 0.2 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3466 PF11949.8 CCH58030.1 - 0.015 14.0 0.1 0.024 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) AAA_14 PF13173.6 CCH58030.1 - 0.016 15.2 0.2 0.13 12.3 0.2 2.4 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCH58030.1 - 0.036 13.1 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CCH58030.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CCH58030.1 - 0.063 13.7 1.4 0.64 10.4 0.0 3.4 3 1 1 4 4 4 0 RNA helicase AAA_7 PF12775.7 CCH58030.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CCH58030.1 - 0.12 12.2 0.0 0.12 12.2 0.0 2.9 2 1 1 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 CCH58030.1 - 0.22 11.4 1.3 0.27 11.1 0.1 1.8 2 0 0 2 2 1 0 RsgA GTPase WD40 PF00400.32 CCH58031.1 - 2.2e-11 44.1 7.1 0.00076 20.2 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat RQC PF09382.10 CCH58032.1 - 1.2e-25 89.5 0.1 2.3e-25 88.6 0.1 1.5 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 CCH58032.1 - 8.8e-23 80.8 0.2 4.1e-18 65.7 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 CCH58032.1 - 2.2e-21 76.4 0.0 5.8e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_Sgs1 PF11408.8 CCH58032.1 - 5.3e-21 74.5 0.0 2.5e-20 72.3 0.0 2.3 1 0 0 1 1 1 1 Sgs1 RecQ helicase RecQ_Zn_bind PF16124.5 CCH58032.1 - 3.8e-15 56.4 7.9 3.8e-15 56.4 7.9 2.4 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 CCH58032.1 - 8.4e-07 29.2 0.0 8.4e-07 29.2 0.0 3.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Rhodanese PF00581.20 CCH58032.1 - 0.023 15.2 0.5 0.37 11.3 0.0 3.0 3 0 0 3 3 3 0 Rhodanese-like domain Ribosomal_L28 PF00830.19 CCH58034.1 - 1.3e-16 60.5 0.1 2.4e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L28 family DNA_pol_D_N PF18018.1 CCH58034.1 - 0.00096 19.3 0.1 0.027 14.6 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain Ribosomal_L36e PF01158.18 CCH58035.1 - 2.3e-35 120.7 4.0 2.5e-35 120.6 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 CCH58035.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP-alpha_N PF04086.13 CCH58036.1 - 0.047 13.6 5.9 0.056 13.4 5.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cyclin_N PF00134.23 CCH58037.1 - 4.7e-37 126.6 0.0 9.3e-37 125.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RXT2_N PF08595.11 CCH58037.1 - 0.071 13.1 4.0 0.14 12.2 4.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF3138 PF11336.8 CCH58037.1 - 0.12 11.0 2.8 0.17 10.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DNA_pol_phi PF04931.13 CCH58037.1 - 0.4 8.7 6.1 0.69 8.0 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi ASFV_J13L PF05568.11 CCH58037.1 - 0.6 9.8 7.7 1.1 9.0 7.7 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_60s PF00428.19 CCH58037.1 - 1.3 9.7 8.3 2.9 8.5 8.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFA1_2 PF17317.2 CCH58038.1 - 8.7e-22 76.6 0.2 9.2e-22 76.5 0.2 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 Rot1 PF10681.9 CCH58039.1 - 1.4e-93 312.2 0.6 1.8e-93 311.8 0.6 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VHS PF00790.19 CCH58040.1 - 6.7e-35 120.0 0.2 1.7e-34 118.7 0.2 1.7 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 CCH58040.1 - 5.1e-19 68.2 6.5 1.8e-18 66.4 6.5 1.9 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CCH58040.1 - 1.5e-05 24.6 10.6 0.0015 18.3 3.3 3.5 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 CCH58040.1 - 0.002 18.4 0.2 0.0095 16.2 0.2 2.2 1 0 0 1 1 1 1 GAT domain SART-1 PF03343.13 CCH58040.1 - 0.014 14.0 14.0 0.028 13.0 14.0 1.4 1 0 0 1 1 1 0 SART-1 family zf-AN1 PF01428.16 CCH58040.1 - 0.027 14.6 7.2 0.061 13.5 7.2 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger DnaB_2 PF07261.11 CCH58040.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Replication initiation and membrane attachment Homeobox_KN PF05920.11 CCH58040.1 - 1.5 8.8 5.0 22 5.1 0.4 2.9 2 0 0 2 2 2 0 Homeobox KN domain Autophagy_N PF03986.13 CCH58041.1 - 8e-39 132.7 0.7 8e-39 132.7 0.7 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CCH58041.1 - 8.4e-16 58.3 0.1 4.2e-15 56.1 0.1 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CCH58041.1 - 2.3e-14 52.6 2.3 4.9e-14 51.5 2.3 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal ChapFlgA PF13144.6 CCH58041.1 - 0.16 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Chaperone for flagella basal body P-ring formation LCAT PF02450.15 CCH58042.1 - 1.4e-127 426.1 0.1 1.8e-127 425.8 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CCH58042.1 - 0.00026 21.7 0.0 0.00045 20.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 CCH58042.1 - 0.0034 16.9 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Hydrolase_4 PF12146.8 CCH58042.1 - 0.025 13.9 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 CCH58042.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 CCH58042.1 - 0.12 12.0 0.0 0.52 9.9 0.0 2.0 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF676 PF05057.14 CCH58042.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 CCH58042.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ABC2_membrane PF01061.24 CCH58043.1 - 1.2e-82 276.4 53.3 8.8e-42 142.9 25.2 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCH58043.1 - 2.6e-39 134.9 0.4 7.8e-18 65.3 0.0 3.6 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CCH58043.1 - 1.1e-35 121.4 6.4 8.7e-32 108.9 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CCH58043.1 - 1.9e-13 50.8 0.0 6.1e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CCH58043.1 - 1.7e-06 27.7 0.1 6.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCH58043.1 - 5.2e-06 26.7 0.1 0.051 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CCH58043.1 - 9.4e-06 26.2 0.5 0.00067 20.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 CCH58043.1 - 3.4e-05 24.3 0.0 0.0051 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCH58043.1 - 7.4e-05 22.7 0.5 0.0048 16.8 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CCH58043.1 - 0.00023 21.1 0.1 0.29 10.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CCH58043.1 - 0.00046 19.4 8.8 0.00046 19.4 8.8 4.2 4 1 0 4 4 2 2 ABC-2 family transporter protein AAA_28 PF13521.6 CCH58043.1 - 0.00065 20.0 0.1 0.14 12.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 CCH58043.1 - 0.00073 19.0 0.1 0.19 11.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 CCH58043.1 - 0.00082 19.0 0.7 0.58 9.7 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CCH58043.1 - 0.0011 18.7 1.5 0.01 15.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH58043.1 - 0.0012 19.1 0.8 0.38 11.0 0.2 2.9 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCH58043.1 - 0.0093 16.0 0.3 4.9 7.3 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 CCH58043.1 - 0.037 13.9 1.3 5 7.0 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 CCH58043.1 - 0.049 13.3 1.9 5.1 6.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CCH58043.1 - 0.06 13.8 0.2 0.06 13.8 0.2 4.2 3 2 1 4 4 4 0 AAA domain PduV-EutP PF10662.9 CCH58043.1 - 0.11 12.2 1.4 15 5.4 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CCH58043.1 - 0.75 10.0 3.0 38 4.5 0.1 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L23 PF00276.20 CCH58044.1 - 2.5e-10 40.6 0.0 5.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpb2_6 PF00562.28 CCH58045.1 - 3.7e-126 421.3 0.2 6.4e-126 420.6 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCH58045.1 - 2.1e-73 246.2 0.0 3.5e-73 245.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCH58045.1 - 1.1e-51 175.1 0.0 2.3e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCH58045.1 - 7.3e-34 116.0 0.1 1.8e-33 114.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCH58045.1 - 1.6e-25 89.2 0.3 3.8e-25 87.9 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCH58045.1 - 2.6e-24 85.1 0.1 6.5e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCH58045.1 - 2.6e-18 66.3 1.9 2.6e-18 66.3 1.9 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 NAD_binding_5 PF07994.12 CCH58045.1 - 0.027 13.9 0.2 0.082 12.3 0.1 1.7 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase DIT1_PvcA PF05141.12 CCH58046.1 - 2e-99 332.5 0.0 2.7e-99 332.1 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 CCH58047.1 - 5.4e-57 193.6 0.0 6.9e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pribosyltran PF00156.27 CCH58048.1 - 5e-09 35.9 0.0 7.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.19 CCH58048.1 - 0.034 13.0 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Utp12 PF04003.12 CCH58049.1 - 3.2e-21 75.7 2.7 5.6e-21 74.9 2.7 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family SesA PF17107.5 CCH58049.1 - 0.075 13.2 0.5 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases IBN_N PF03810.19 CCH58050.1 - 1.4e-14 53.7 1.7 7.6e-14 51.4 0.7 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CCH58050.1 - 0.1 13.2 0.3 1.2 9.7 0.1 3.0 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region MDM31_MDM32 PF08118.11 CCH58051.1 - 1.7e-90 304.2 20.1 4.6e-82 276.4 13.9 3.4 2 1 1 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins DUF748 PF05359.11 CCH58051.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) Actin PF00022.19 CCH58052.1 - 2.6e-25 88.9 0.0 2.1e-16 59.6 0.0 3.7 3 1 0 3 3 3 3 Actin Actin_micro PF17003.5 CCH58052.1 - 2.8e-10 39.9 8.8 5.1e-05 22.6 0.2 3.0 2 2 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CCH58052.1 - 0.00012 21.1 0.3 0.037 12.8 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCH58052.1 - 0.081 13.4 0.8 0.31 11.5 0.9 2.1 1 1 0 1 1 1 0 Cell division protein FtsA UBA_4 PF14555.6 CCH58053.1 - 0.0085 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Metallophos PF00149.28 CCH58054.1 - 2.5e-09 37.9 0.1 5.8e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RhoGAP PF00620.27 CCH58055.1 - 3.5e-30 104.9 0.2 1.8e-20 73.3 0.0 2.7 2 0 0 2 2 2 2 RhoGAP domain Med12 PF09497.10 CCH58055.1 - 0.096 13.0 1.0 18 5.7 0.0 3.1 3 0 0 3 3 3 0 Transcription mediator complex subunit Med12 BAR PF03114.18 CCH58056.1 - 6.1e-65 219.2 7.8 7.9e-65 218.8 7.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CCH58056.1 - 7.9e-14 51.0 0.1 1.6e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH58056.1 - 9.9e-12 44.5 0.3 3.1e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CCH58056.1 - 1.8e-06 27.5 0.0 4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain ERCC4 PF02732.15 CCH58057.1 - 1.1e-20 74.4 0.4 1.1e-20 74.4 0.4 2.3 3 1 0 3 3 3 1 ERCC4 domain HTH_45 PF14947.6 CCH58057.1 - 0.028 14.4 0.0 0.073 13.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix HHH_3 PF12836.7 CCH58057.1 - 0.071 13.4 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif GTP_EFTU PF00009.27 CCH58058.1 - 1.3e-66 223.8 0.4 1.9e-66 223.3 0.4 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCH58058.1 - 6.5e-32 109.8 0.0 4e-31 107.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCH58058.1 - 9.9e-22 76.8 0.0 3.3e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CCH58058.1 - 3.5e-13 49.4 0.0 1.4e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CCH58058.1 - 2.4e-12 47.0 0.0 8.9e-12 45.2 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH58058.1 - 0.00031 20.8 0.2 0.00065 19.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PX PF00787.24 CCH58059.1 - 1.5e-08 34.6 0.9 4.2e-08 33.2 0.9 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CCH58059.1 - 0.0048 16.5 13.3 0.023 14.2 13.3 2.0 1 1 0 1 1 1 1 Vps5 C terminal like PHM7_cyt PF14703.6 CCH58059.1 - 1.7 8.8 8.9 1 9.5 5.9 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter IZUMO PF15005.6 CCH58059.1 - 5.8 7.4 6.8 0.8 10.2 1.0 2.6 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Gpr1_Fun34_YaaH PF01184.19 CCH58060.1 - 1.1e-72 244.0 17.8 1.4e-72 243.6 17.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_60s PF00428.19 CCH58061.1 - 1.2e-23 83.5 14.8 1.4e-23 83.3 14.8 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Treacle PF03546.14 CCH58061.1 - 0.0025 16.7 4.6 0.0026 16.7 4.6 1.2 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle EF-hand_14 PF17959.1 CCH58061.1 - 0.065 13.6 0.0 0.096 13.0 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Mito_carr PF00153.27 CCH58062.1 - 6e-58 192.8 3.0 1.6e-19 69.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CCH58064.1 - 2.3e-13 49.7 0.0 4.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CCH58064.1 - 0.0033 17.9 13.7 0.0033 17.9 13.7 3.2 2 2 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 BRAP2 PF07576.12 CCH58064.1 - 0.022 15.0 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 CCH58064.1 - 0.027 14.5 0.0 0.075 13.0 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Afi1 PF07792.12 CCH58065.1 - 2.1e-11 44.4 0.1 2.1e-11 44.4 0.1 4.3 2 2 1 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 CCH58065.1 - 6.2e-08 32.6 3.2 6.2e-08 32.6 3.2 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis TPP_enzyme_N PF02776.18 CCH58066.1 - 4.9e-21 75.1 0.0 1.1e-20 74.0 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH58066.1 - 9.6e-17 61.0 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH58066.1 - 1.8e-12 47.3 0.0 3.8e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Band_7 PF01145.25 CCH58066.1 - 0.17 11.9 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 SPFH domain / Band 7 family AIRC PF00731.20 CCH58067.1 - 5.7e-65 217.4 2.1 7.2e-65 217.1 1.3 1.6 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 CCH58067.1 - 5.9e-55 185.5 0.0 1.1e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CCH58067.1 - 1.1e-17 63.5 1.1 1.4e-17 63.1 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CCH58067.1 - 6.3e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 CCH58067.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 CCH58067.1 - 0.0086 15.6 0.0 0.04 13.5 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.18 CCH58067.1 - 0.019 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCH58067.1 - 0.024 14.0 0.0 0.061 12.6 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CoA_binding_2 PF13380.6 CCH58067.1 - 0.11 13.0 0.1 22 5.6 0.0 2.5 1 1 1 2 2 2 0 CoA binding domain RhoGAP PF00620.27 CCH58068.1 - 4.1e-42 143.6 2.2 4.1e-42 143.6 2.2 2.6 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 CCH58068.1 - 2.5e-13 50.0 27.6 1.5e-06 28.3 6.9 2.8 2 0 0 2 2 2 2 LIM domain APG6_N PF17675.1 CCH58068.1 - 0.0041 17.7 5.1 0.014 15.9 5.1 1.9 1 0 0 1 1 1 1 Apg6 coiled-coil region KASH_CCD PF14662.6 CCH58068.1 - 0.006 16.4 3.4 0.014 15.2 3.4 1.7 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH CLZ PF16526.5 CCH58068.1 - 0.061 13.7 3.5 0.29 11.5 3.5 2.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3086 PF11285.8 CCH58068.1 - 0.2 10.7 2.4 0.45 9.6 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) ZapB PF06005.12 CCH58068.1 - 0.3 11.6 3.8 0.47 10.9 2.4 2.1 1 1 0 1 1 1 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 CCH58068.1 - 0.65 10.1 7.0 1.7 8.7 4.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CCH58068.1 - 1.7 8.4 4.2 5.7 6.8 4.2 1.9 1 0 0 1 1 1 0 Septum formation initiator Osmo_CC PF08946.10 CCH58068.1 - 2 8.7 5.0 3.1 8.1 2.8 2.3 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Pyr_redox_2 PF07992.14 CCH58069.1 - 9.3e-10 38.2 0.0 6.4e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCH58069.1 - 2.5e-05 24.4 0.0 4.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CCH58069.1 - 0.0034 17.4 0.0 0.01 15.8 0.0 1.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CCH58069.1 - 0.013 15.9 0.0 3.6 8.1 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 CCH58069.1 - 0.22 11.1 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lipase_GDSL_2 PF13472.6 CCH58070.1 - 6e-19 69.1 0.0 8.4e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CCH58070.1 - 2.2e-11 44.1 0.0 7.1e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BCS1_N PF08740.11 CCH58071.1 - 4.4e-46 157.2 0.1 6.2e-46 156.7 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CCH58071.1 - 8.8e-23 81.2 0.0 1.6e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH58071.1 - 0.00095 19.6 0.0 0.0044 17.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CCH58071.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CCH58071.1 - 0.0027 16.9 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CCH58071.1 - 0.0031 17.5 0.0 0.011 15.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CCH58071.1 - 0.0031 17.2 0.0 0.022 14.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CCH58071.1 - 0.0035 17.5 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCH58071.1 - 0.0043 16.6 0.0 0.017 14.7 0.0 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CCH58071.1 - 0.0045 17.5 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCH58071.1 - 0.0079 16.1 0.0 0.2 11.6 0.0 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_29 PF13555.6 CCH58071.1 - 0.017 14.9 0.0 0.061 13.1 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain NACHT PF05729.12 CCH58071.1 - 0.02 14.8 0.0 0.31 10.9 0.0 2.7 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.27 CCH58071.1 - 0.021 15.3 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 CCH58071.1 - 0.022 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CCH58071.1 - 0.028 14.8 0.0 0.092 13.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_22 PF13401.6 CCH58071.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CCH58071.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 CCH58071.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CCH58071.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CCH58071.1 - 0.18 12.2 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.12 CCH58072.1 - 2.9e-24 85.1 3.0 5.5e-24 84.1 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH58072.1 - 2e-17 63.4 0.0 3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCH58072.1 - 4.2e-06 26.2 0.1 6.9e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCH58072.1 - 0.0042 16.4 0.3 0.0076 15.6 0.1 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain YTH PF04146.15 CCH58073.1 - 8.3e-33 113.7 1.7 8.3e-33 113.7 1.7 2.6 2 1 0 2 2 2 1 YT521-B-like domain COQ7 PF03232.13 CCH58074.1 - 8.9e-74 246.9 0.0 1.1e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 EF-hand_1 PF00036.32 CCH58075.1 - 1.3e-26 90.1 6.3 7.6e-08 31.4 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CCH58075.1 - 4.7e-24 84.6 5.5 1e-17 64.3 0.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCH58075.1 - 1.2e-23 81.0 4.8 5.1e-06 26.0 0.2 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 CCH58075.1 - 2.6e-19 67.8 4.1 2.3e-05 23.7 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CCH58075.1 - 4.1e-19 68.2 6.9 5.2e-08 32.6 0.1 3.8 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CCH58075.1 - 3.7e-06 26.8 5.8 0.26 11.2 0.0 3.5 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CCH58075.1 - 4.9e-05 23.6 0.1 0.004 17.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CCH58075.1 - 0.00049 20.4 0.9 0.1 12.9 0.2 3.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.15 CCH58075.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain PHB_acc_N PF07879.11 CCH58075.1 - 0.095 12.8 0.3 6.5 6.9 0.1 2.7 3 0 0 3 3 3 0 PHB/PHA accumulation regulator DNA-binding domain GPP34 PF05719.11 CCH58076.1 - 5.8e-50 170.2 0.0 7e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.28 CCH58077.1 - 2.5e-77 260.7 3.6 3.3e-77 260.3 3.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BolA PF01722.18 CCH58077.1 - 0.17 12.2 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 BolA-like protein RAI1 PF08652.11 CCH58078.1 - 0.043 14.0 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease FHA PF00498.26 CCH58080.1 - 3.4e-05 24.1 0.1 0.00017 21.9 0.1 2.3 1 0 0 1 1 1 1 FHA domain PTP_tm PF18861.1 CCH58080.1 - 0.019 14.9 0.5 0.092 12.7 0.5 2.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Aldo_ket_red PF00248.21 CCH58081.1 - 6.4e-44 150.3 0.0 4.3e-42 144.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CCH58082.1 - 2.4e-42 145.1 0.1 3.6e-40 138.0 0.1 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family zf-HIT PF04438.16 CCH58083.1 - 2.9e-09 36.6 10.9 4.9e-09 35.9 10.9 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 CCH58083.1 - 2.1 6.1 7.0 2.7 5.8 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 V-ATPase_G PF03179.15 CCH58084.1 - 1.1e-31 109.5 12.4 1.2e-31 109.3 12.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 CCH58084.1 - 0.0042 17.5 10.0 0.0057 17.1 10.0 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CCH58084.1 - 0.0073 16.4 8.0 0.0073 16.4 8.0 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DUF3552 PF12072.8 CCH58084.1 - 0.11 11.9 17.7 0.027 13.9 9.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) Atrophin-1 PF03154.15 CCH58084.1 - 4.1 5.6 5.1 4.7 5.4 5.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family RRF PF01765.19 CCH58085.1 - 1.1e-33 116.5 8.9 1.7e-33 115.8 8.9 1.3 1 0 0 1 1 1 1 Ribosome recycling factor NifW PF03206.14 CCH58085.1 - 0.023 15.2 1.7 0.059 13.9 0.3 2.0 2 0 0 2 2 2 0 Nitrogen fixation protein NifW CmlA_N PF18456.1 CCH58085.1 - 0.11 11.7 2.4 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain Swm2 PF17083.5 CCH58085.1 - 0.45 10.5 0.1 0.45 10.5 0.1 3.5 3 2 1 4 4 4 0 Nucleolar protein Swm2 FIVAR PF07554.13 CCH58085.1 - 3.9 8.3 7.7 11 6.9 0.1 3.0 3 0 0 3 3 3 0 FIVAR domain DUF4771 PF15995.5 CCH58085.1 - 8.1 6.7 8.7 2.4 8.4 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) FCH PF00611.23 CCH58085.1 - 8.7 6.7 7.7 0.97 9.8 0.3 2.7 2 2 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain RNB PF00773.19 CCH58086.1 - 2.2e-59 201.4 2.0 2.2e-59 201.4 2.0 3.0 3 0 0 3 3 3 1 RNB domain Dis3l2_C_term PF17877.1 CCH58086.1 - 3.8e-23 81.6 0.0 2.2e-22 79.2 0.0 2.5 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 CCH58086.1 - 1.1e-22 79.8 0.0 3.4e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CCH58086.1 - 4.6e-06 26.7 0.0 0.0011 19.1 0.0 3.1 3 0 0 3 3 3 1 Cold shock domain OB_RNB PF08206.11 CCH58086.1 - 0.0022 17.6 0.1 0.65 9.7 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Rrp44_CSD1 PF17216.3 CCH58086.1 - 0.024 14.4 0.0 0.024 14.4 0.0 3.0 4 0 0 4 4 4 0 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CCH58086.1 - 0.05 13.6 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 S1 domain SPAM PF02090.15 CCH58086.1 - 0.67 9.8 5.3 14 5.5 0.1 2.7 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein HAUS6_N PF14661.6 CCH58086.1 - 8.3 5.9 12.1 46 3.5 11.2 2.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus LptF_LptG PF03739.14 CCH58086.1 - 9.9 4.9 8.7 20 3.9 8.7 1.5 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Cadherin_C_2 PF16492.5 CCH58087.1 - 0.067 13.9 1.0 4.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Claudin_3 PF06653.11 CCH58087.1 - 4.1 7.3 13.3 0.78 9.7 1.9 2.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like DUF2149 PF09919.9 CCH58087.1 - 9.1 6.6 6.1 8 6.8 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) Pyridoxal_deC PF00282.19 CCH58088.1 - 3.8e-21 75.3 0.0 5.3e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CCH58088.1 - 2.5e-05 23.8 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCH58088.1 - 0.00013 21.1 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Rrn6 PF10214.9 CCH58089.1 - 0.11 11.0 3.6 0.12 10.9 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4614 PF15391.6 CCH58089.1 - 0.14 12.1 5.7 0.22 11.5 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF2525 PF10733.9 CCH58089.1 - 0.15 12.3 0.2 0.37 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2525) Presenilin PF01080.17 CCH58089.1 - 0.8 8.4 3.2 0.91 8.2 3.2 1.1 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 CCH58089.1 - 2.2 7.0 3.9 2.7 6.7 3.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FA_hydroxylase PF04116.13 CCH58090.1 - 1.5e-22 80.4 11.8 1.5e-22 80.4 11.8 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily EF-hand_like PF09279.11 CCH58090.1 - 0.064 13.8 0.3 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like AATF-Che1 PF13339.6 CCH58091.1 - 7.1e-24 85.1 4.2 7.1e-24 85.1 4.2 2.7 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CCH58091.1 - 2.2e-23 82.5 0.1 2.2e-23 82.5 0.1 3.1 3 1 1 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal AA_kinase PF00696.28 CCH58092.1 - 8.8e-34 117.2 0.3 2.4e-33 115.7 0.1 1.7 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 CCH58092.1 - 5.4e-19 67.9 0.1 1.9e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 PUA domain Nucleotid_trans PF03407.16 CCH58092.1 - 0.14 12.1 0.2 0.86 9.5 0.1 2.0 1 1 1 2 2 2 0 Nucleotide-diphospho-sugar transferase CPSF_A PF03178.15 CCH58093.1 - 1e-82 278.0 0.0 3.2e-82 276.4 0.0 1.9 1 0 0 1 1 1 1 CPSF A subunit region SDA1 PF05285.12 CCH58093.1 - 1.2 8.5 15.3 2.9 7.3 8.2 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CCH58093.1 - 1.7 6.7 18.5 0.072 11.3 7.0 2.1 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 CCH58093.1 - 9.4 4.4 16.4 4.6 5.4 0.1 2.1 2 0 0 2 2 2 0 CDC45-like protein PIG-F PF06699.11 CCH58094.1 - 1.2e-26 94.0 21.6 2.9e-25 89.5 21.6 2.3 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Claudin_3 PF06653.11 CCH58094.1 - 0.012 15.6 9.2 0.012 15.6 9.2 1.5 1 1 0 1 1 1 0 Tight junction protein, Claudin-like Flp_Fap PF04964.14 CCH58094.1 - 0.046 13.6 0.7 0.097 12.5 0.7 1.5 1 0 0 1 1 1 0 Flp/Fap pilin component FUSC-like PF12805.7 CCH58094.1 - 1.7 7.6 5.9 2.3 7.2 5.4 1.5 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF2070 PF09843.9 CCH58094.1 - 6.8 4.9 9.1 7.3 4.7 9.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zn_clus PF00172.18 CCH58095.1 - 2.7e-07 30.6 8.6 5.7e-07 29.6 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med6 PF04934.14 CCH58096.1 - 1.1e-47 161.1 0.0 1.5e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.10 CCH58097.1 - 2.4e-18 65.9 0.8 3.8e-18 65.3 0.8 1.3 1 0 0 1 1 1 1 IGR protein motif F-box-like PF12937.7 CCH58098.1 - 0.00036 20.4 0.4 0.00091 19.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like TbpB_C PF17483.2 CCH58098.1 - 0.28 11.6 2.2 34 4.9 0.1 3.3 2 1 1 3 3 3 0 C-lobe handle domain of Tf-binding protein B FNIP PF05725.12 CCH58098.1 - 0.28 11.4 4.0 1.6 9.0 0.2 3.6 3 1 0 3 3 3 0 FNIP Repeat MIR PF02815.19 CCH58099.1 - 3.6e-08 33.5 0.1 1.6e-07 31.4 0.2 1.8 1 1 0 2 2 2 1 MIR domain PMT PF02366.18 CCH58099.1 - 0.00024 20.8 15.5 0.00088 18.9 15.5 2.0 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PsbI PF02532.14 CCH58099.1 - 0.28 11.1 2.6 2.4 8.1 2.6 2.7 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) MerT PF02411.15 CCH58099.1 - 4.7 7.3 8.7 3.7 7.6 0.0 3.5 3 1 0 3 3 3 0 MerT mercuric transport protein Noggin PF05806.12 CCH58100.1 - 0.031 14.2 1.8 0.043 13.7 1.8 1.2 1 0 0 1 1 1 0 Noggin SLC12 PF03522.15 CCH58100.1 - 0.28 10.2 10.8 0.33 9.9 10.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CCH58100.1 - 6.2 5.5 9.2 7.3 5.2 9.2 1.1 1 0 0 1 1 1 0 Presenilin RNase_P_p30 PF01876.16 CCH58101.1 - 2.6e-66 223.2 0.1 3.2e-66 222.9 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit p30 BSD PF03909.17 CCH58103.1 - 8.9e-23 80.1 2.2 8.8e-12 44.9 0.3 3.1 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CCH58103.1 - 4.7e-16 58.9 7.2 1.4e-12 47.7 0.1 3.6 4 0 0 4 4 4 2 TFIIH p62 subunit, N-terminal domain DUF3349 PF11829.8 CCH58103.1 - 0.18 12.6 2.3 1.1 10.1 2.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) Brix PF04427.18 CCH58104.1 - 1e-48 166.0 4.0 2e-48 165.1 4.0 1.4 1 0 0 1 1 1 1 Brix domain DUF2514 PF10721.9 CCH58104.1 - 2.3 8.3 12.4 0.031 14.3 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Menin PF05053.13 CCH58104.1 - 3.3 5.9 16.2 5.3 5.3 16.2 1.2 1 0 0 1 1 1 0 Menin FYVE PF01363.21 CCH58105.1 - 4.5e-21 74.7 5.4 4.5e-21 74.7 5.4 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CCH58105.1 - 1.8e-06 28.2 3.4 1.8e-06 28.2 3.4 4.1 4 1 0 4 4 3 1 Ring finger domain zf-RING_11 PF17123.5 CCH58105.1 - 0.0018 18.0 4.8 0.0018 18.0 4.8 2.6 3 0 0 3 3 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CCH58105.1 - 0.0023 17.9 4.5 0.0023 17.9 4.5 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCH58105.1 - 0.022 14.6 1.8 0.022 14.6 1.8 4.8 6 1 0 6 6 5 0 Zinc finger, C3HC4 type (RING finger) PilI PF10623.9 CCH58105.1 - 0.46 10.7 3.6 1.9 8.7 0.0 2.6 3 0 0 3 3 2 0 Plasmid conjugative transfer protein PilI zinc_ribbon_12 PF11331.8 CCH58105.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.4 3 1 1 4 4 4 0 Probable zinc-ribbon domain RNF220 PF15926.5 CCH58105.1 - 1.7 8.2 5.6 0.75 9.4 0.5 2.4 1 1 2 3 3 3 0 E3 ubiquitin-protein ligase RNF220 zf-C2HC5 PF06221.13 CCH58105.1 - 2.4 8.2 10.8 5.5 7.1 1.9 3.7 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type zinc-ribbons_6 PF07191.12 CCH58105.1 - 3.5 7.7 17.2 0.84 9.7 4.1 3.6 4 0 0 4 4 4 0 zinc-ribbons FYVE_2 PF02318.16 CCH58105.1 - 8 6.7 12.3 0.84 9.9 6.7 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger Ins_P5_2-kin PF06090.12 CCH58106.1 - 6.3e-22 78.4 1.0 1.1e-21 77.7 1.0 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase P4Ha_N PF08336.11 CCH58106.1 - 0.028 14.4 0.2 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Methyltransf_23 PF13489.6 CCH58107.1 - 1.3e-22 80.4 0.0 2.2e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH58107.1 - 4.9e-14 52.9 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH58107.1 - 1.1e-11 45.3 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH58107.1 - 1.2e-09 38.2 0.0 2.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH58107.1 - 1.5e-09 38.4 0.0 3.8e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH58107.1 - 4e-09 36.1 0.0 7.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF4435 PF14491.6 CCH58107.1 - 0.026 14.4 7.7 0.032 14.1 3.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) TMEMspv1-c74-12 PF11044.8 CCH58107.1 - 0.046 13.7 1.6 0.16 12.0 1.6 1.9 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein ECR1_N PF14382.6 CCH58108.1 - 1.5e-14 53.5 0.1 2.8e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CCH58108.1 - 3.4e-10 40.1 0.2 7e-10 39.1 0.2 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 CCH58108.1 - 0.099 13.3 1.1 10 6.8 0.0 3.2 3 1 1 4 4 4 0 Exosome component EXOSC1/CSL4 Cyclin_N PF00134.23 CCH58109.1 - 1.3e-07 31.4 0.5 1.9e-07 30.9 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCH58109.1 - 7.5e-05 23.1 0.5 7.5e-05 23.1 0.5 1.7 2 0 0 2 2 2 1 Cyclin HIM1 PF08732.10 CCH58110.1 - 7.5e-43 146.0 2.1 1.6e-42 144.9 2.1 1.6 1 0 0 1 1 1 1 HIM1 Scs3p PF10261.9 CCH58111.1 - 1.8e-17 63.7 13.7 1.3e-10 41.2 1.1 2.4 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 CCH58111.1 - 2.8e-05 23.9 1.9 2.8e-05 23.9 1.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily Orai-1 PF07856.12 CCH58111.1 - 0.0016 18.1 6.0 0.031 14.0 3.4 2.3 2 0 0 2 2 2 2 Mediator of CRAC channel activity SQHop_cyclase_C PF13243.6 CCH58112.1 - 1.1e-41 142.9 0.1 4e-41 141.2 0.0 1.7 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CCH58112.1 - 8.1e-36 123.6 0.0 8.9e-29 100.5 0.0 3.1 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CCH58112.1 - 9.3e-27 92.5 0.8 5.7e-08 32.4 0.1 4.8 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 CCH58112.1 - 0.031 13.6 1.1 1.6 8.0 0.0 3.2 2 1 1 3 3 3 0 Pectic acid lyase HCV_NS4a PF01006.20 CCH58112.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DASH_Dad4 PF08650.10 CCH58113.1 - 2.3e-28 97.9 0.5 2.6e-28 97.8 0.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 VPS13_C PF16909.5 CCH58113.1 - 0.072 12.9 0.2 0.084 12.7 0.2 1.0 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Oxysterol_BP PF01237.18 CCH58114.1 - 8.1e-97 324.4 4.1 8.3e-96 321.1 4.1 2.5 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CCH58114.1 - 9.9e-31 105.9 0.5 3e-30 104.3 0.5 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CCH58114.1 - 0.00024 21.5 3.0 0.00042 20.8 0.7 2.8 2 0 0 2 2 2 1 PH domain Asparaginase PF00710.20 CCH58115.1 - 5.4e-55 185.9 0.1 1.1e-54 184.8 0.0 1.6 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CCH58115.1 - 1e-18 67.6 0.0 3e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ribosomal_L19 PF01245.20 CCH58115.1 - 0.0035 17.2 0.0 2.2 8.3 0.0 3.2 3 0 0 3 3 3 1 Ribosomal protein L19 DUF3982 PF13138.6 CCH58115.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) Abhydrolase_6 PF12697.7 CCH58116.1 - 1.4e-13 52.0 0.0 2.4e-13 51.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCH58116.1 - 2.7e-12 46.9 0.0 4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH58116.1 - 0.00095 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 VirJ PF06057.11 CCH58116.1 - 0.0017 18.3 0.0 0.08 12.8 0.0 2.3 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) PAF-AH_p_II PF03403.13 CCH58116.1 - 0.005 15.4 0.1 0.41 9.1 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 CCH58116.1 - 0.043 13.5 0.3 0.087 12.5 0.3 1.6 1 1 0 1 1 1 0 PGAP1-like protein PBP PF01161.20 CCH58117.1 - 4.6e-06 27.0 0.1 8.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATP-synt_E PF05680.12 CCH58118.1 - 1.3e-16 60.7 0.0 1.4e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain SpoIIE PF07228.12 CCH58119.1 - 6.9e-29 101.1 0.0 9.4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CCH58119.1 - 1.1e-05 25.2 0.2 0.0036 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C MIF4G PF02854.19 CCH58120.1 - 2.2e-39 135.3 35.3 1.3e-22 80.5 5.8 4.2 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 CCH58120.1 - 8.1e-28 97.8 12.4 8.1e-28 97.8 12.4 2.4 2 1 1 3 3 3 1 Up-frameshift suppressor 2 Nop14 PF04147.12 CCH58120.1 - 3.4 5.8 35.7 4.1 5.5 31.7 2.4 2 0 0 2 2 2 0 Nop14-like family ANAPC4_WD40 PF12894.7 CCH58121.1 - 3.2e-08 33.8 4.9 0.25 11.7 0.1 6.3 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH58121.1 - 1.1e-05 26.1 22.0 4.8 8.2 0.5 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat WD40_like PF17005.5 CCH58121.1 - 0.018 14.4 3.8 0.056 12.8 0.5 3.3 2 2 1 3 3 3 0 WD40-like domain Pkinase PF00069.25 CCH58122.1 - 3.5e-46 157.7 0.5 1.7e-32 112.8 0.0 3.1 2 1 1 3 3 3 2 Protein kinase domain Ribonuc_2-5A PF06479.12 CCH58122.1 - 7.1e-37 126.4 2.4 7.1e-37 126.4 2.4 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CCH58122.1 - 6.6e-27 94.4 0.0 2.3e-24 86.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 CCH58122.1 - 3.2e-05 23.6 0.1 0.2 11.7 0.0 2.8 3 0 0 3 3 3 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 CCH58122.1 - 0.00071 18.5 0.4 0.00071 18.5 0.4 2.1 2 1 0 2 2 2 1 Fungal protein kinase PQQ_2 PF13360.6 CCH58122.1 - 0.021 14.4 0.0 0.27 10.8 0.0 2.1 1 1 0 1 1 1 0 PQQ-like domain Kdo PF06293.14 CCH58122.1 - 0.028 13.8 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Swi5 PF07061.11 CCH58123.1 - 4.4e-23 81.2 3.8 4.8e-23 81.0 3.8 1.0 1 0 0 1 1 1 1 Swi5 Bap31_Bap29_C PF18035.1 CCH58123.1 - 0.0012 18.7 0.6 0.0012 18.7 0.6 1.9 1 1 1 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain HTH_DeoR PF08220.12 CCH58123.1 - 0.0075 16.0 0.6 0.018 14.8 0.2 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain Spc7 PF08317.11 CCH58123.1 - 0.05 12.5 3.5 0.048 12.5 3.5 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein SPC22 PF04573.12 CCH58123.1 - 0.069 12.6 0.1 0.081 12.4 0.1 1.1 1 0 0 1 1 1 0 Signal peptidase subunit HALZ PF02183.18 CCH58123.1 - 0.086 13.1 2.5 0.086 13.1 2.5 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper FapA PF03961.13 CCH58123.1 - 0.23 10.1 5.0 0.23 10.0 5.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A VASt PF16016.5 CCH58124.1 - 3.5e-75 251.6 1.2 2.2e-37 128.9 0.2 2.6 2 0 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCH58124.1 - 1.1e-28 99.3 0.1 2.8e-28 98.1 0.1 1.8 1 0 0 1 1 1 1 GRAM domain NBP1 PF08537.10 CCH58124.1 - 0.032 13.7 9.9 0.28 10.5 1.6 3.9 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 GST_N_4 PF17172.4 CCH58124.1 - 0.051 14.3 0.7 0.32 11.8 0.1 2.5 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Spore_III_AF PF09581.10 CCH58124.1 - 0.11 12.5 0.5 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF1230 PF06799.11 CCH58124.1 - 0.13 12.4 0.1 20 5.2 0.0 2.5 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 PKcGMP_CC PF16808.5 CCH58124.1 - 3.1 7.7 5.4 0.33 10.8 0.3 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SAM35 PF10806.8 CCH58126.1 - 5.4e-35 120.4 0.9 5.4e-35 120.4 0.9 2.2 3 0 0 3 3 3 1 SAM35, subunit of SAM coomplex STE PF02200.16 CCH58127.1 - 7.2e-60 200.2 2.9 2.2e-59 198.7 2.9 1.9 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.14 CCH58128.1 - 8.6e-77 258.6 3.2 1.4e-76 257.8 3.2 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Hamartin PF04388.12 CCH58128.1 - 0.07 11.8 8.8 0.097 11.3 8.8 1.1 1 0 0 1 1 1 0 Hamartin protein Ipi1_N PF12333.8 CCH58129.1 - 1.9e-24 86.2 0.8 7.2e-24 84.3 0.3 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 CCH58129.1 - 0.027 14.7 0.0 0.28 11.6 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat Dimerisation2 PF16864.5 CCH58129.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain RRM_1 PF00076.22 CCH58130.1 - 3.5e-25 87.6 0.0 1e-15 57.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCH58130.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.6 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.6 CCH58130.1 - 0.00015 21.3 0.0 0.0053 16.3 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCH58130.1 - 0.0031 17.3 0.0 0.034 14.0 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CCH58130.1 - 0.0068 16.5 0.0 0.036 14.2 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CCH58130.1 - 0.024 14.6 0.0 0.044 13.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF4203 PF13886.6 CCH58130.1 - 0.067 12.8 0.7 0.11 12.2 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) BRAP2 PF07576.12 CCH58130.1 - 0.14 12.4 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 SNF2_N PF00176.23 CCH58131.1 - 1.8e-65 221.0 0.1 4.8e-65 219.6 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH58131.1 - 1.2e-19 70.7 1.0 1.4e-18 67.3 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 CCH58131.1 - 5.7e-15 55.4 2.0 5.7e-15 55.4 2.0 2.6 2 1 1 3 3 3 1 HSA ResIII PF04851.15 CCH58131.1 - 7.6e-12 45.6 0.0 7.6e-12 45.6 0.0 5.6 6 2 0 6 6 6 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCH58131.1 - 3.7e-07 30.1 0.3 7.6e-06 25.8 0.0 3.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase DCB PF16213.5 CCH58132.1 - 0.00085 19.0 0.2 0.0029 17.3 0.2 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 BDV_M PF16520.5 CCH58132.1 - 0.1 13.0 2.1 0.21 12.0 0.2 2.5 2 0 0 2 2 2 0 ssRNA-binding matrix protein of Bornaviridae IBN_N PF03810.19 CCH58132.1 - 0.84 9.6 6.9 0.28 11.1 0.6 3.6 4 0 0 4 4 4 0 Importin-beta N-terminal domain MMR_HSR1 PF01926.23 CCH58133.1 - 3e-17 62.7 0.2 5.7e-17 61.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH58133.1 - 1e-07 32.1 2.2 3.8e-06 26.9 0.5 2.6 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CCH58133.1 - 1.8e-07 31.4 2.0 0.0014 18.7 0.0 2.8 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 CCH58133.1 - 1.3e-05 24.6 0.1 2.1e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CCH58133.1 - 4.2e-05 23.2 0.1 0.00021 20.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 CCH58133.1 - 4.5e-05 22.9 1.4 7.8e-05 22.1 0.1 1.9 2 0 0 2 2 2 1 Septin Roc PF08477.13 CCH58133.1 - 0.0001 22.5 3.6 0.00012 22.3 0.1 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCH58133.1 - 0.00012 21.6 0.3 0.00032 20.2 0.2 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CCH58133.1 - 0.00039 20.0 0.1 0.0007 19.2 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CCH58133.1 - 0.0011 18.4 0.4 0.0017 17.8 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CCH58133.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.4 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.6 CCH58133.1 - 0.0027 17.4 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CCH58133.1 - 0.0034 16.8 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family RdDM_RDM1 PF09187.10 CCH58133.1 - 0.014 15.4 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA-directed DNA methylation 1 ATPase_2 PF01637.18 CCH58133.1 - 0.019 14.9 1.3 0.046 13.6 0.0 2.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea MobB PF03205.14 CCH58133.1 - 0.047 13.6 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 CCH58133.1 - 0.056 14.0 0.2 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 CCH58133.1 - 0.083 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Gar1 PF04410.14 CCH58134.1 - 1.3e-40 138.7 0.0 1.6e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Ribosomal_S15 PF00312.22 CCH58135.1 - 2.8e-27 94.7 0.1 2.8e-27 94.7 0.1 2.4 3 0 0 3 3 3 1 Ribosomal protein S15 ING PF12998.7 CCH58136.1 - 1.2e-11 45.0 5.2 1.2e-11 45.0 5.2 2.2 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCH58136.1 - 2.2e-06 27.4 10.1 5e-06 26.3 10.1 1.6 1 0 0 1 1 1 1 PHD-finger EOS1 PF12326.8 CCH58136.1 - 0.42 10.5 2.6 0.46 10.4 0.4 2.0 2 0 0 2 2 2 0 N-glycosylation protein PHD_2 PF13831.6 CCH58136.1 - 0.43 10.2 4.3 0.95 9.1 4.3 1.6 1 0 0 1 1 1 0 PHD-finger DUF4808 PF16066.5 CCH58136.1 - 3.9 8.1 6.9 7.7 7.1 4.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4808) zf-HC5HC2H PF13771.6 CCH58136.1 - 4.1 7.7 12.5 0.11 12.8 5.4 2.2 3 1 0 3 3 3 0 PHD-like zinc-binding domain CCDC53 PF10152.9 CCH58136.1 - 4.7 7.6 12.5 2.6 8.4 8.1 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF4112 PF13430.6 CCH58137.1 - 1.6e-24 86.2 0.3 2.4e-24 85.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) EcsC PF12787.7 CCH58137.1 - 2.9e-05 23.9 0.9 0.0061 16.3 0.1 2.9 1 1 2 3 3 3 2 EcsC protein family tRNA-synt_1d PF00750.19 CCH58138.1 - 6.5e-102 341.0 4.5 8.5e-102 340.6 4.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CCH58138.1 - 4e-26 91.5 0.3 1.1e-25 90.1 0.3 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CCH58138.1 - 0.0061 17.1 0.0 0.017 15.7 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Sugar_tr PF00083.24 CCH58139.1 - 6.6e-159 529.6 30.1 7.7e-159 529.4 30.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58139.1 - 8e-31 107.2 32.3 1.6e-29 103.0 17.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58139.1 - 5.6e-07 28.4 4.6 8.2e-07 27.8 1.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCH58139.1 - 0.4 9.0 6.0 0.15 10.5 2.4 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector DUF1772 PF08592.11 CCH58139.1 - 0.78 10.1 6.8 0.61 10.4 0.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 CCH58140.1 - 2.7e-164 547.3 34.0 3.1e-164 547.1 34.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58140.1 - 8.9e-30 103.8 29.3 1.8e-29 102.8 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58140.1 - 0.00093 17.7 2.0 0.00093 17.7 2.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Deltameth_res PF16020.5 CCH58140.1 - 0.34 10.8 3.2 9.6 6.2 0.1 3.3 3 0 0 3 3 3 0 Deltamethrin resistance Sugar_tr PF00083.24 CCH58141.1 - 1.4e-151 505.4 21.5 1.6e-151 505.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58141.1 - 4.9e-31 107.9 24.5 7.5e-28 97.5 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58142.1 - 3.3e-155 517.4 27.3 3.7e-155 517.2 27.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58142.1 - 3.5e-29 101.8 29.1 1e-25 90.5 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCH58142.1 - 2.1 8.7 9.3 0.67 10.3 0.7 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) MtrG PF04210.13 CCH58142.1 - 3.1 7.7 5.3 14 5.7 0.2 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Sugar_tr PF00083.24 CCH58143.1 - 2.4e-164 547.5 31.5 2.8e-164 547.3 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58143.1 - 1.4e-33 116.3 25.4 2.8e-33 115.3 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58143.1 - 0.00062 18.3 2.8 0.001 17.6 2.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 CCH58143.1 - 2.2 8.6 6.9 1.1 9.6 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 CCH58144.1 - 2.5e-153 511.2 28.6 2.8e-153 511.0 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58144.1 - 1.8e-29 102.8 27.2 6e-27 94.5 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58144.1 - 2.8e-05 22.7 1.4 2.8e-05 22.7 1.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 CCH58144.1 - 0.041 14.2 3.1 0.41 11.0 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) ATP1G1_PLM_MAT8 PF02038.16 CCH58144.1 - 3.6 7.1 7.9 3 7.4 0.9 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Sugar_tr PF00083.24 CCH58145.1 - 1.8e-162 541.3 31.0 2.1e-162 541.1 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58145.1 - 7e-32 110.7 27.9 7.8e-32 110.6 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58146.1 - 8.9e-156 519.3 32.3 1e-155 519.0 32.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58146.1 - 7.9e-33 113.8 31.0 5.2e-29 101.3 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58146.1 - 0.00022 19.8 1.9 0.0004 18.9 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CCH58147.1 - 6.3e-157 523.1 31.1 7.2e-157 522.8 31.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58147.1 - 3.9e-32 111.5 32.6 7.1e-29 100.8 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58147.1 - 0.00033 19.2 1.6 0.00053 18.5 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CCH58148.1 - 9.3e-165 548.9 31.6 1.1e-164 548.7 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58148.1 - 5.5e-34 117.6 28.5 2.2e-31 109.1 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58148.1 - 0.0023 16.4 1.5 0.0023 16.4 1.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.16 CCH58148.1 - 0.047 13.1 2.7 0.71 9.4 0.6 3.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1772 PF08592.11 CCH58148.1 - 4.8 7.5 7.1 0.51 10.7 0.2 2.9 4 1 0 4 4 4 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 CCH58149.1 - 3.5e-153 510.7 31.5 4.1e-153 510.5 31.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58149.1 - 2.6e-28 99.0 31.0 6.5e-25 87.8 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58149.1 - 6.3e-05 21.6 1.7 0.00011 20.8 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.16 CCH58149.1 - 1.6 8.2 10.7 0.34 10.4 0.7 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Sugar_tr PF00083.24 CCH58150.1 - 1e-167 558.6 34.0 1.2e-167 558.4 34.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58150.1 - 1.5e-31 109.6 40.1 1.3e-26 93.4 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1_C PF17187.4 CCH58151.1 - 1.8e-71 239.3 5.1 5.6e-71 237.7 5.1 1.9 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CCH58151.1 - 4.3e-70 235.0 4.2 1.3e-69 233.4 4.2 2.0 1 1 0 1 1 1 1 Svf1-like N-terminal lipocalin domain CENP-B_dimeris PF09026.10 CCH58151.1 - 8.4 6.9 15.7 3 8.3 11.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sec23_trunk PF04811.15 CCH58152.1 - 7.9e-48 163.1 0.1 1.3e-47 162.5 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CCH58152.1 - 1.6e-11 44.1 4.3 3.7e-11 42.9 4.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CCH58152.1 - 4e-10 40.3 0.0 1.3e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCH58152.1 - 8.4e-06 25.5 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CCH58152.1 - 0.00026 20.8 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat FAT PF02259.23 CCH58153.1 - 4.4e-69 233.3 7.6 4.4e-69 233.3 7.6 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CCH58153.1 - 1.7e-46 159.1 0.4 5.8e-46 157.3 0.4 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CCH58153.1 - 0.0017 18.1 0.0 0.0052 16.6 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF1160 PF06648.11 CCH58153.1 - 0.71 9.9 7.8 0.48 10.4 0.4 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1160) PGP_phosphatase PF09419.10 CCH58154.1 - 6.8e-64 214.5 0.0 7.7e-64 214.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CCH58154.1 - 4e-06 26.8 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Rep-A_N PF04057.12 CCH58155.1 - 0.024 14.7 0.4 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Pkinase PF00069.25 CCH58156.1 - 4.4e-69 232.8 0.0 8.2e-69 231.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58156.1 - 2.7e-50 171.1 0.0 4.6e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH58156.1 - 5.9e-05 22.0 0.1 5.9e-05 22.0 0.1 2.7 4 0 0 4 4 4 1 Fungal protein kinase Kinase-like PF14531.6 CCH58156.1 - 7.4e-05 22.2 0.0 0.00073 18.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CCH58156.1 - 0.12 12.0 0.1 0.39 10.3 0.1 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SBE2 PF17076.5 CCH58157.1 - 4.1e-188 627.4 73.9 4.1e-188 627.4 73.9 3.2 1 1 1 2 2 2 1 SBE2, cell-wall formation PQ-loop PF04193.14 CCH58158.1 - 1.9e-30 104.4 20.9 2.7e-17 62.3 2.9 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 CCH58158.1 - 0.00025 21.9 6.9 0.018 15.8 0.2 2.9 1 1 1 2 2 2 2 ER lumen protein retaining receptor DUF3397 PF11877.8 CCH58158.1 - 0.22 11.7 11.5 0.18 12.1 7.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) Herpes_LMP1 PF05297.11 CCH58158.1 - 0.46 9.6 2.4 0.36 10.0 1.1 1.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) MtN3_slv PF03083.16 CCH58158.1 - 1.8 8.7 14.4 1.3 9.1 0.6 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange PX PF00787.24 CCH58159.1 - 3.9e-14 52.6 1.3 5.6e-14 52.1 1.3 1.4 1 1 0 1 1 1 1 PX domain Spc110_C PF18520.1 CCH58160.1 - 0.00046 19.7 2.1 0.00046 19.7 2.1 3.4 3 0 0 3 3 3 1 Spindle pole body component 110 C-terminal domain 23S_rRNA_IVP PF05635.11 CCH58161.1 - 0.01 16.1 0.3 0.012 15.8 0.3 1.1 1 0 0 1 1 1 0 23S rRNA-intervening sequence protein VHS PF00790.19 CCH58162.1 - 1.3e-46 158.0 0.0 5e-46 156.1 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CCH58162.1 - 9.5e-20 71.0 1.4 3.2e-19 69.3 1.4 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 CCH58162.1 - 1.6e-19 69.9 3.0 1.6e-19 69.9 3.0 3.2 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 CCH58162.1 - 2e-05 24.1 0.1 2e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 GGA N-GAT domain Stm1_N PF09598.10 CCH58162.1 - 0.79 10.6 4.9 1.1e+02 3.7 4.5 3.4 2 1 0 2 2 2 0 Stm1 TraG-D_C PF12696.7 CCH58162.1 - 6.2 6.8 7.7 2 8.4 1.8 2.7 1 1 1 2 2 2 0 TraM recognition site of TraD and TraG Myb_DNA-bind_6 PF13921.6 CCH58163.1 - 5.8e-09 36.1 0.5 5.8e-09 36.1 0.5 4.4 3 1 1 4 4 4 1 Myb-like DNA-binding domain EMP24_GP25L PF01105.24 CCH58164.1 - 3.6e-43 147.6 1.9 4.3e-43 147.4 1.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 CCH58164.1 - 0.083 13.3 1.1 1.7 9.1 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CBP_BcsF PF11120.8 CCH58164.1 - 2.9 8.1 4.7 0.71 10.0 0.5 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF ThiF PF00899.21 CCH58165.1 - 1.1e-59 201.8 0.0 1.6e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CCH58165.1 - 4.1e-14 53.0 0.0 1.6e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Atg14 PF10186.9 CCH58165.1 - 0.0032 16.6 2.7 0.016 14.3 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Shikimate_DH PF01488.20 CCH58165.1 - 0.0034 17.5 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Mto2_bdg PF12808.7 CCH58165.1 - 0.12 12.6 4.4 0.095 13.0 2.3 1.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc24 PF08286.11 CCH58165.1 - 0.27 11.5 1.7 1.6 9.0 0.8 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cys_Met_Meta_PP PF01053.20 CCH58166.1 - 1.3e-64 218.2 0.0 4.3e-64 216.4 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCH58166.1 - 5.2e-07 28.9 0.0 2.9e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCH58166.1 - 0.00079 18.7 0.1 0.0028 16.9 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Alpha-amylase PF00128.24 CCH58166.1 - 0.023 14.3 0.1 0.056 13.0 0.0 1.6 2 0 0 2 2 2 0 Alpha amylase, catalytic domain gag_pre-integrs PF13976.6 CCH58166.1 - 0.025 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Peptidase_M18 PF02127.15 CCH58167.1 - 2.1e-178 593.6 0.1 2.4e-178 593.4 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CCH58167.1 - 5e-08 32.3 0.0 3.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Sugar_tr PF00083.24 CCH58168.1 - 1e-153 512.5 30.7 1.2e-153 512.3 30.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58168.1 - 1.3e-29 103.2 29.6 3.6e-26 91.9 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58168.1 - 7.3e-05 21.4 3.1 0.00012 20.6 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rad60-SLD PF11976.8 CCH58169.1 - 5.9e-28 96.5 5.6 8.1e-26 89.7 3.5 2.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCH58169.1 - 3.6e-05 23.4 1.3 0.00011 21.9 1.3 1.9 1 0 0 1 1 1 1 Ubiquitin family PrpR_N PF06506.11 CCH58169.1 - 0.15 11.6 1.0 0.49 10.0 1.0 1.8 1 1 0 1 1 1 0 Propionate catabolism activator RNA_pol_Rpb1_5 PF04998.17 CCH58170.1 - 9.2e-83 277.7 0.1 1.3e-82 277.3 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CCH58170.1 - 1.4e-81 274.3 0.0 3.8e-81 272.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CCH58170.1 - 1.2e-75 253.3 0.3 3.5e-75 251.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCH58170.1 - 7e-39 133.3 0.0 2e-38 131.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCH58170.1 - 9.4e-32 109.2 0.1 2.6e-31 107.7 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.13 CCH58171.1 - 4.5e-21 74.7 14.2 6.6e-21 74.1 14.2 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 CCH58172.1 - 1.2e-40 139.0 0.0 2.7e-40 137.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCH58172.1 - 3.2e-19 68.6 0.3 6.6e-19 67.6 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CCH58172.1 - 6.5e-09 35.5 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CCH58172.1 - 1.4e-05 25.5 0.1 0.014 15.8 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CCH58172.1 - 4.7e-05 23.6 0.2 0.00022 21.4 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCH58172.1 - 7.9e-05 22.7 1.2 0.00053 20.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCH58172.1 - 0.00083 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCH58172.1 - 0.00087 19.6 0.2 0.07 13.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CCH58172.1 - 0.004 17.3 0.1 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CCH58172.1 - 0.01 15.3 0.2 0.064 12.7 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CCH58172.1 - 0.012 15.0 0.1 0.036 13.4 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CCH58172.1 - 0.017 14.8 0.3 0.06 13.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 CCH58172.1 - 0.023 13.9 0.0 0.043 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CCH58172.1 - 0.053 13.3 0.6 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCH58172.1 - 0.075 13.4 0.4 0.21 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CCH58172.1 - 0.083 12.2 0.8 0.43 9.9 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 CCH58172.1 - 0.086 12.3 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CCH58172.1 - 0.1 12.3 1.6 0.33 10.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain JIP_LZII PF16471.5 CCH58172.1 - 0.11 12.7 4.6 0.32 11.2 4.6 1.8 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II DUF1192 PF06698.11 CCH58172.1 - 0.13 12.3 1.0 0.34 11.0 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ThylakoidFormat PF11264.8 CCH58172.1 - 0.14 11.8 1.7 0.25 11.0 1.7 1.5 1 0 0 1 1 1 0 Thylakoid formation protein WD40 PF00400.32 CCH58173.1 - 4.4e-30 103.3 7.2 1.2e-05 26.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58173.1 - 8e-12 45.3 0.0 0.0017 18.6 0.0 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CCH58173.1 - 0.05 12.6 0.2 0.43 9.6 0.0 2.4 2 1 0 3 3 3 0 Coatomer WD associated region BBS2_Mid PF14783.6 CCH58173.1 - 0.12 12.4 0.1 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 CCH58173.1 - 0.45 10.5 2.6 0.61 10.1 0.0 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RIO1 PF01163.22 CCH58174.1 - 1.6e-71 239.8 2.2 1.6e-71 239.8 2.2 2.6 3 0 0 3 3 3 1 RIO1 family Cwf_Cwc_15 PF04889.12 CCH58174.1 - 0.0089 15.8 26.1 0.015 15.0 26.1 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein APH PF01636.23 CCH58174.1 - 0.045 13.7 0.0 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YL1 PF05764.13 CCH58174.1 - 0.21 11.7 30.4 0.34 11.0 30.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CCH58174.1 - 1.6 6.9 28.9 2.3 6.3 28.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CCH58174.1 - 6.4 4.9 27.0 9.9 4.3 27.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Peptidase_M20 PF01546.28 CCH58175.1 - 7.7e-26 91.1 0.0 1.3e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCH58175.1 - 2.6e-10 40.2 0.0 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RXT2_N PF08595.11 CCH58176.1 - 0.078 13.0 4.1 0.1 12.6 4.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 CCH58176.1 - 0.32 10.1 11.8 0.39 9.8 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 CCH58176.1 - 0.42 10.3 2.3 0.58 9.8 2.3 1.2 1 0 0 1 1 1 0 FAM176 family Pes-10 PF07149.11 CCH58176.1 - 0.51 9.4 5.6 0.6 9.1 5.6 1.1 1 0 0 1 1 1 0 Pes-10 RRN3 PF05327.11 CCH58176.1 - 0.96 7.9 5.7 1.1 7.7 5.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_membrane PF00664.23 CCH58178.1 - 3e-93 312.4 38.7 1.2e-52 179.3 16.7 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCH58178.1 - 1.4e-46 158.5 1.9 5e-28 98.3 1.8 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCH58178.1 - 4.5e-09 36.1 10.7 0.00023 20.7 4.1 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCH58178.1 - 5.5e-06 26.4 0.2 0.086 12.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CCH58178.1 - 1e-05 25.2 0.3 0.097 12.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCH58178.1 - 0.00042 20.3 0.0 0.31 10.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCH58178.1 - 0.00046 20.6 0.3 1.7 9.0 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CCH58178.1 - 0.0015 19.1 8.2 0.035 14.6 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 CCH58178.1 - 0.0017 18.3 1.8 0.38 10.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCH58178.1 - 0.0029 17.4 10.9 0.25 11.0 0.3 3.7 4 0 0 4 4 4 2 AAA ATPase domain NTPase_1 PF03266.15 CCH58178.1 - 0.0076 16.2 0.6 4.3 7.2 0.0 2.5 2 0 0 2 2 2 2 NTPase Roc PF08477.13 CCH58178.1 - 0.013 15.7 0.2 4.8 7.4 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CCH58178.1 - 0.014 15.6 0.5 3.4 7.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain TMEM132D_C PF15706.5 CCH58178.1 - 0.021 14.6 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF87 PF01935.17 CCH58178.1 - 0.049 13.7 5.4 1 9.4 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Zeta_toxin PF06414.12 CCH58178.1 - 0.056 12.7 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 CCH58178.1 - 0.059 12.9 0.0 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CCH58178.1 - 0.14 11.8 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCH58178.1 - 0.15 11.8 0.2 5.8 6.6 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 CCH58178.1 - 0.15 11.6 0.1 5.6 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CCH58178.1 - 0.23 11.5 3.4 1.7 8.7 0.1 2.7 3 0 0 3 3 2 0 Dynamin family NACHT PF05729.12 CCH58178.1 - 0.78 9.6 3.0 0.95 9.4 0.1 2.5 3 0 0 3 3 2 0 NACHT domain AIG1 PF04548.16 CCH58178.1 - 0.87 8.9 6.8 0.38 10.0 0.1 2.8 3 0 0 3 3 3 0 AIG1 family Tmemb_18A PF09771.9 CCH58178.1 - 1.2 9.6 4.6 1.4 9.3 1.8 2.7 2 0 0 2 2 1 0 Transmembrane protein 188 Avl9 PF09794.9 CCH58179.1 - 2.9e-141 470.6 2.2 4.5e-141 469.9 2.2 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CCH58179.1 - 1.9e-06 27.8 2.1 0.0023 17.9 0.1 3.1 2 1 0 2 2 2 1 Stabilization of polarity axis DUF2347 PF09804.9 CCH58179.1 - 9.1e-05 22.2 0.2 9.1e-05 22.2 0.2 3.8 2 2 1 3 3 3 1 Uncharacterized conserved protein (DUF2347) DUF1388 PF07142.12 CCH58179.1 - 0.0073 16.2 0.4 0.015 15.2 0.4 1.5 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) DENN PF02141.21 CCH58179.1 - 0.0078 16.2 1.2 0.084 12.8 1.2 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain efThoc1 PF11957.8 CCH58180.1 - 6.9e-114 381.2 42.6 6.9e-114 381.2 42.6 2.1 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Lactamase_B_6 PF16661.5 CCH58181.1 - 1.2e-72 243.5 0.2 2.1e-72 242.6 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CCH58181.1 - 7.2e-22 78.4 0.4 7.2e-22 78.4 0.4 3.8 2 2 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CCH58181.1 - 0.028 14.7 0.0 0.095 13.0 0.0 1.9 1 0 0 1 1 1 0 Beta-Casp domain SF1-HH PF16275.5 CCH58182.1 - 7.2e-38 129.4 0.1 7.2e-38 129.4 0.1 2.3 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CCH58182.1 - 5.1e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 CCH58182.1 - 9.5e-07 28.6 12.6 0.00017 21.5 2.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CCH58182.1 - 0.0073 16.3 5.4 0.3 11.1 1.3 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 CCH58182.1 - 0.069 12.9 4.4 3.7 7.3 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle Lar_restr_allev PF14354.6 CCH58182.1 - 0.14 12.6 5.1 0.3 11.5 5.1 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-CCHC_6 PF15288.6 CCH58182.1 - 0.27 11.1 7.8 0.28 11.1 0.6 2.8 2 0 0 2 2 2 0 Zinc knuckle zf-HIT PF04438.16 CCH58182.1 - 0.36 10.8 4.7 8.3 6.4 1.1 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-CCHC_2 PF13696.6 CCH58182.1 - 0.62 9.9 14.7 0.13 12.1 2.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 CCH58182.1 - 1.2 8.9 6.7 0.6 9.9 1.0 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger TPR_14 PF13428.6 CCH58183.1 - 2.4e-18 65.2 0.0 0.012 16.4 0.0 7.5 6 2 2 8 8 8 5 Tetratricopeptide repeat HAT PF02184.16 CCH58183.1 - 4.7e-14 52.0 42.6 3.4e-06 26.9 0.1 9.8 11 0 0 11 11 11 6 HAT (Half-A-TPR) repeat Suf PF05843.14 CCH58183.1 - 8.2e-09 35.9 27.9 0.00025 21.2 4.3 5.5 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CCH58183.1 - 7.3e-08 32.8 0.0 0.003 18.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH58183.1 - 3.8e-05 23.8 2.7 0.063 13.7 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCH58183.1 - 0.00011 21.5 1.7 0.84 8.8 0.4 4.5 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCH58183.1 - 0.00031 21.2 4.4 11 7.0 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CCH58183.1 - 0.001 19.1 20.9 0.005 16.8 4.0 5.7 5 1 1 6 6 6 2 Mad3/BUB1 homology region 1 U3_assoc_6 PF08640.11 CCH58183.1 - 0.0058 16.7 16.8 0.0078 16.3 2.7 4.7 3 2 2 5 5 5 2 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.6 CCH58183.1 - 0.02 15.1 9.3 10 6.6 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH58183.1 - 0.25 11.4 1.9 19 5.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCH58183.1 - 3.6 8.3 4.5 66 4.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MTS PF05175.14 CCH58184.1 - 2.9e-08 33.4 0.0 5.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CCH58184.1 - 0.00017 21.1 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CCH58184.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CCH58184.1 - 0.034 14.0 0.0 0.097 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CCH58184.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Dopey_N PF04118.14 CCH58185.1 - 8.6e-111 369.9 4.5 8.6e-111 369.9 4.5 3.2 2 1 1 3 3 3 1 Dopey, N-terminal SCAPER_N PF16501.5 CCH58185.1 - 0.062 13.3 0.1 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum Abhydrolase_2 PF02230.16 CCH58186.1 - 4.6e-59 199.8 0.0 5.2e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CCH58186.1 - 5.3e-09 36.0 0.1 1.9e-08 34.2 0.1 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CCH58186.1 - 1.2e-07 31.5 0.0 8.5e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CCH58186.1 - 4.3e-05 22.9 0.0 0.002 17.4 0.0 2.7 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCH58186.1 - 0.00017 22.3 0.0 0.0072 16.9 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CCH58186.1 - 0.00059 19.4 0.0 0.0058 16.1 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIP PF03583.14 CCH58186.1 - 0.033 13.5 0.0 0.14 11.4 0.0 1.8 1 1 0 2 2 2 0 Secretory lipase Abhydrolase_3 PF07859.13 CCH58186.1 - 0.064 13.1 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold WD40 PF00400.32 CCH58187.1 - 4.9e-14 52.5 12.1 4.5e-05 24.1 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat zf-RING_2 PF13639.6 CCH58188.1 - 3.5e-08 33.6 11.0 6.6e-07 29.6 6.5 2.3 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 CCH58188.1 - 4.6e-08 32.8 3.9 1.1e-07 31.5 3.9 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CCH58188.1 - 6.8e-07 29.1 7.0 9.3e-06 25.5 3.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CCH58188.1 - 1.1e-06 28.8 5.8 2.3e-06 27.8 3.0 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CCH58188.1 - 4.2e-06 26.5 7.5 6.6e-06 25.9 4.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH58188.1 - 2.5e-05 24.3 6.0 2.5e-05 24.3 6.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CCH58188.1 - 5.9e-05 22.8 10.3 6.6e-05 22.7 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH58188.1 - 0.0001 22.1 10.9 0.00027 20.7 6.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH58188.1 - 0.0002 21.3 10.3 0.0019 18.2 4.7 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_10 PF16685.5 CCH58188.1 - 0.00034 20.7 2.6 0.00087 19.4 2.6 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CCH58188.1 - 0.0012 18.8 0.3 0.0069 16.4 0.3 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CCH58188.1 - 0.82 9.5 7.5 0.28 11.0 3.9 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Asp PF00026.23 CCH58189.1 - 4.5e-70 236.6 3.2 9.3e-70 235.5 3.2 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH58189.1 - 2.1e-11 44.4 1.7 1.8e-10 41.3 1.7 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CCH58189.1 - 0.015 15.9 0.3 15 6.3 0.1 3.2 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 CCH58189.1 - 0.021 15.4 0.3 25 5.5 0.0 3.5 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease DUF3127 PF11325.8 CCH58190.1 - 0.093 13.0 0.9 22 5.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3127) FeoC PF09012.10 CCH58190.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator pPIWI_RE_REase PF18154.1 CCH58190.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 REase associating with pPIWI_RE Cullin_binding PF03556.15 CCH58191.1 - 1.3e-25 90.2 8.9 1.3e-25 90.2 8.9 1.5 2 0 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 CCH58191.1 - 1.8e-10 40.4 0.2 6.4e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 UBA-like domain WIYLD PF10440.9 CCH58191.1 - 0.2 11.5 3.0 12 5.8 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain TFIID_20kDa PF03847.13 CCH58192.1 - 1.6e-26 92.6 0.1 4e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A WD40 PF00400.32 CCH58193.1 - 5.2e-49 163.2 32.9 1e-05 26.2 0.1 11.3 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp12 PF04003.12 CCH58193.1 - 5e-17 62.2 0.2 8.6e-17 61.4 0.2 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CCH58193.1 - 5e-16 58.8 13.5 0.0036 17.6 0.0 8.7 4 2 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CCH58193.1 - 5e-08 32.1 11.0 0.0047 15.7 0.1 5.1 2 2 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 CCH58193.1 - 8.6e-08 31.3 9.3 0.0014 17.4 0.1 5.8 5 3 0 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CCH58193.1 - 2.1e-06 27.3 8.6 0.015 14.7 0.0 4.2 4 0 0 4 4 4 3 WD40-like domain PALB2_WD40 PF16756.5 CCH58193.1 - 0.00036 19.6 7.9 0.12 11.3 0.1 4.6 5 0 0 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 CCH58193.1 - 0.0017 18.1 1.4 3.2 7.4 0.0 3.6 4 0 0 4 4 4 2 TUP1-like enhancer of split eIF2A PF08662.11 CCH58193.1 - 0.0017 18.2 1.5 0.4 10.5 0.0 4.2 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCH58193.1 - 0.012 14.6 7.5 3.3 6.6 0.1 6.1 2 2 7 9 9 9 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-C2H2 PF00096.26 CCH58194.1 - 4.4e-09 36.3 16.3 0.003 17.9 1.3 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH58194.1 - 0.00021 21.9 11.8 0.17 12.8 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCH58194.1 - 0.033 14.6 9.7 0.55 10.8 0.0 3.9 3 0 0 3 3 3 0 Zinc-finger double domain LIM PF00412.22 CCH58194.1 - 0.12 12.6 1.7 0.37 11.1 1.7 1.8 1 0 0 1 1 1 0 LIM domain zf_ZIC PF18366.1 CCH58194.1 - 1.5 9.0 3.4 9.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Zic proteins zinc finger domain PhoQ_Sensor PF08918.10 CCH58194.1 - 5.6 6.8 7.0 1.3 8.8 0.8 2.5 2 0 0 2 2 2 0 PhoQ Sensor HVSL PF09749.9 CCH58195.1 - 4e-22 78.9 0.8 4.6e-22 78.7 0.5 1.3 1 1 0 1 1 1 1 Uncharacterised conserved protein Spore_III_AF PF09581.10 CCH58195.1 - 0.05 13.6 1.0 0.087 12.8 1.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Coatomer_b_Cpla PF14806.6 CCH58195.1 - 0.074 13.0 0.1 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform DDHD PF02862.17 CCH58195.1 - 7.9 6.6 7.2 8.2 6.5 0.0 3.0 2 1 0 3 3 3 0 DDHD domain Choline_kinase PF01633.20 CCH58196.1 - 1e-66 224.6 0.1 1.4e-66 224.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 CCH58196.1 - 1.8e-11 43.5 0.1 4.2e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 CCH58196.1 - 5.6e-08 33.0 0.0 0.0037 17.2 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF3445 PF11927.8 CCH58196.1 - 0.1 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) HTH_37 PF13744.6 CCH58196.1 - 0.12 12.3 0.1 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Slx4 PF09494.10 CCH58197.1 - 9.3e-15 54.3 0.0 2.5e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Slx4 endonuclease TFR_dimer PF04253.15 CCH58198.1 - 1e-21 77.2 0.0 2.6e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCH58198.1 - 9.5e-21 74.4 0.0 1.8e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCH58198.1 - 8.9e-10 38.5 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 CCH58198.1 - 0.02 14.4 0.0 0.043 13.3 0.0 1.5 1 0 0 1 1 1 0 Nicastrin Crp PF00325.20 CCH58198.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family RWD PF05773.22 CCH58199.1 - 2.4e-25 89.1 8.3 2.4e-25 89.1 8.3 2.3 2 1 0 2 2 2 1 RWD domain UEV PF05743.13 CCH58199.1 - 0.0061 16.4 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 UEV domain UPF0061 PF02696.14 CCH58199.1 - 0.49 9.1 3.7 0.61 8.8 3.7 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family ENTH PF01417.20 CCH58200.1 - 3.2e-30 104.7 0.1 5.8e-30 103.9 0.1 1.4 1 0 0 1 1 1 1 ENTH domain Pro_isomerase PF00160.21 CCH58201.1 - 1.8e-48 164.8 0.0 2e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_polI_A14 PF08203.11 CCH58202.1 - 2.9e-28 98.4 0.4 2.9e-28 98.4 0.4 1.5 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 SSP160 PF06933.11 CCH58202.1 - 4.3 5.4 10.3 0.1 10.8 1.7 1.9 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 SAC3_GANP PF03399.16 CCH58203.1 - 1.7e-98 329.6 1.8 3.1e-97 325.5 0.5 2.3 2 0 0 2 2 2 2 SAC3/GANP family SAC3 PF12209.8 CCH58203.1 - 8e-13 48.4 1.2 2.8e-12 46.7 1.2 2.0 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain Na_H_Exchanger PF00999.21 CCH58204.1 - 2.2e-78 263.7 23.5 2.8e-78 263.4 23.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YwcE PF17368.2 CCH58204.1 - 1.7 9.4 5.8 0.2 12.3 0.4 2.3 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE DUF3382 PF11862.8 CCH58204.1 - 4.5 7.6 7.3 2.2 8.6 0.2 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) SLS PF14611.6 CCH58205.1 - 6.1e-38 130.9 1.1 6.1e-38 130.9 1.1 1.7 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator L_lactis_RepB_C PF06430.12 CCH58205.1 - 0.026 14.5 0.1 2.4 8.2 0.1 2.7 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus PAM2 PF07145.15 CCH58206.1 - 0.15 11.8 0.4 12 5.8 0.1 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Diphthami_syn_2 PF01902.17 CCH58207.1 - 3.1e-33 115.1 0.0 2.4e-32 112.2 0.0 2.4 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CCH58207.1 - 1e-19 70.7 0.0 9.3e-11 41.8 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Glyco_hydro81C PF17652.1 CCH58209.1 - 3.1e-62 210.9 3.2 5e-62 210.2 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CCH58209.1 - 9.8e-54 182.7 1.7 1.4e-53 182.1 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Spermine_synth PF01564.17 CCH58210.1 - 6.1e-66 221.4 0.1 9e-66 220.9 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCH58210.1 - 2e-25 88.4 0.0 3.4e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CCH58210.1 - 0.0056 17.4 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH58210.1 - 0.011 16.5 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CCH58210.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.6 CCH58210.1 - 0.034 14.0 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 CCH58210.1 - 0.088 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain WD40 PF00400.32 CCH58211.1 - 0.0065 17.3 0.1 2.3 9.2 0.2 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat LSM PF01423.22 CCH58212.1 - 1e-15 57.2 0.3 1.2e-15 56.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 CCH58212.1 - 0.0081 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CCH58212.1 - 0.04 14.1 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Pep3_Vps18 PF05131.14 CCH58213.1 - 1.3e-40 138.7 0.7 1.3e-40 138.7 0.7 2.8 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CCH58213.1 - 3.8e-09 36.6 16.4 9e-06 25.6 5.5 3.8 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 CCH58213.1 - 0.00031 21.2 9.3 0.00049 20.5 2.1 3.3 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CCH58213.1 - 0.0028 17.2 1.0 0.0073 15.9 1.0 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CCH58213.1 - 0.003 17.6 0.7 0.007 16.4 0.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger YhdB PF14148.6 CCH58213.1 - 0.0046 17.0 0.8 2.7 8.2 0.2 3.0 2 0 0 2 2 2 1 YhdB-like protein zf-RING_5 PF14634.6 CCH58213.1 - 0.0083 16.1 2.2 0.02 14.8 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCH58213.1 - 0.0094 15.8 2.5 0.022 14.6 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phage_Coat_A PF05357.13 CCH58213.1 - 0.011 15.5 0.1 0.031 14.0 0.1 1.8 1 0 0 1 1 1 0 Phage Coat Protein A zf-RING_2 PF13639.6 CCH58213.1 - 0.019 15.3 2.8 0.019 15.3 2.8 1.9 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4 PF00097.25 CCH58213.1 - 0.027 14.3 2.8 0.08 12.8 2.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCH58213.1 - 0.098 13.0 1.5 0.31 11.4 1.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CCH58213.1 - 0.11 12.2 7.8 0.65 9.8 7.9 2.2 1 1 1 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 CCH58213.1 - 0.3 11.2 4.5 0.64 10.1 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger DUF2415 PF10313.9 CCH58214.1 - 1.1e-21 76.4 0.4 2.3e-21 75.4 0.4 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Stb3 PF10330.9 CCH58215.1 - 3e-26 91.3 0.0 6e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein UPF0564 PF10595.9 CCH58215.1 - 1.7 7.6 8.8 5.6 5.9 3.3 2.3 1 1 0 2 2 2 0 Uncharacterised protein family UPF0564 Stm1_N PF09598.10 CCH58216.1 - 1.7e-09 38.4 5.1 1.7e-09 38.4 5.1 4.3 3 2 1 4 4 4 1 Stm1 NUDIX PF00293.28 CCH58217.1 - 1.1e-10 41.7 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Sec7 PF01369.20 CCH58218.1 - 6.4e-72 241.1 2.3 1.7e-71 239.7 0.0 2.8 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CCH58218.1 - 1.1e-40 139.1 3.7 1.1e-40 139.1 3.7 4.0 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CCH58218.1 - 8e-26 89.7 0.2 8e-26 89.7 0.2 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 CCH58218.1 - 6.3e-12 45.5 6.7 4.7e-11 42.7 2.5 3.6 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 HSP20 PF00011.21 CCH58219.1 - 8.1e-12 45.2 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CCH58219.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA RR_TM4-6 PF06459.12 CCH58219.1 - 4.5 7.0 8.6 7 6.4 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTP_EFTU PF00009.27 CCH58220.1 - 2e-45 154.7 0.0 5.6e-45 153.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCH58220.1 - 7.9e-34 116.3 0.6 7.9e-34 116.3 0.6 2.7 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCH58220.1 - 5.2e-09 36.4 0.4 1.8e-08 34.6 0.4 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH58220.1 - 0.00079 19.5 0.5 0.0052 16.9 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Peptidase_U32_C PF16325.5 CCH58220.1 - 0.026 14.8 1.1 0.064 13.5 0.3 2.1 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain TFIIA PF03153.13 CCH58220.1 - 0.23 11.4 37.8 0.32 10.9 37.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 CCH58221.1 - 3.8e-32 111.6 34.0 3.8e-32 111.6 34.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58221.1 - 7.6e-05 21.3 1.1 0.00014 20.5 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIR PF00399.19 CCH58222.1 - 5e-59 194.7 98.9 5.2e-09 35.4 3.5 8.5 7 1 1 8 8 8 7 Yeast PIR protein repeat DUF421 PF04239.12 CCH58222.1 - 0.98 9.2 4.5 26 4.6 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF421) LeuA_dimer PF08502.10 CCH58222.1 - 2.1 8.2 17.0 25 4.8 0.5 4.2 1 1 2 3 3 3 0 LeuA allosteric (dimerisation) domain Zn_clus PF00172.18 CCH58223.1 - 9.3e-10 38.5 8.7 1.6e-09 37.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 CCH58224.1 - 3.8e-33 113.6 3.7 6.1e-33 113.0 3.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH58224.1 - 4.7e-20 71.9 0.0 7.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CCH58224.1 - 5.7e-07 29.2 0.0 8.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CCH58224.1 - 0.044 14.8 0.0 0.081 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GATA PF00320.27 CCH58224.1 - 0.072 12.7 1.3 0.25 11.0 1.3 1.9 1 0 0 1 1 1 0 GATA zinc finger NAD_binding_7 PF13241.6 CCH58224.1 - 0.11 13.0 0.0 0.49 10.8 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 CCH58224.1 - 0.11 13.1 0.1 0.28 11.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCH58224.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Alb1 PF09135.11 CCH58225.1 - 4.6e-23 82.1 12.3 1.3e-22 80.6 12.3 1.8 1 1 0 1 1 1 1 Alb1 Calreticulin PF00262.18 CCH58226.1 - 5.8e-131 436.7 12.0 7.7e-131 436.3 12.0 1.2 1 0 0 1 1 1 1 Calreticulin family Kelch_4 PF13418.6 CCH58227.1 - 2.4e-08 33.9 6.1 0.00013 21.9 0.1 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCH58227.1 - 6.2e-07 29.3 6.0 3.1 7.9 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CCH58227.1 - 7.1e-07 29.3 9.9 0.032 14.5 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 CCH58227.1 - 7.6e-05 22.9 0.8 0.0045 17.2 0.0 4.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CCH58227.1 - 0.00041 19.9 6.9 0.34 10.5 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CCH58227.1 - 0.055 13.5 9.0 4.5 7.4 0.2 5.2 6 0 0 6 6 6 0 Kelch motif GDI PF00996.18 CCH58228.1 - 4.2e-46 157.4 0.0 6.8e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 GDP dissociation inhibitor ssDBP_DBD PF18361.1 CCH58228.1 - 0.011 15.9 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain Ribosomal_L7Ae PF01248.26 CCH58229.1 - 2.4e-20 72.0 0.6 3.2e-20 71.7 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.12 CCH58229.1 - 0.032 14.5 0.6 0.078 13.3 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1269) Rad1 PF02144.16 CCH58230.1 - 7.2e-59 199.1 3.4 1.1e-58 198.6 3.4 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peroxin-22 PF12827.7 CCH58231.1 - 4.7e-17 61.9 3.6 6e-17 61.6 3.6 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family CH PF00307.31 CCH58232.1 - 9.9e-16 57.9 0.1 2.2e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.11 CCH58232.1 - 0.033 14.4 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 CDC24 Calponin TRP PF06011.12 CCH58233.1 - 4.8e-154 513.2 36.8 6e-154 512.9 36.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCH58233.1 - 1.2e-42 145.5 2.9 2.1e-42 144.8 2.9 1.4 1 0 0 1 1 1 1 ML-like domain Phage_holin_2_3 PF16080.5 CCH58233.1 - 0.061 13.1 2.1 0.1 12.4 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DLH PF01738.18 CCH58234.1 - 2.1e-33 115.7 0.3 2.4e-33 115.5 0.3 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 CCH58234.1 - 0.081 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ras PF00071.22 CCH58235.1 - 4.7e-27 94.6 0.0 1.1e-13 51.1 0.0 2.7 2 1 0 2 2 2 2 Ras family EF_assoc_1 PF08355.12 CCH58235.1 - 1.4e-25 88.7 0.2 3.2e-25 87.5 0.2 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 CCH58235.1 - 9.5e-24 83.2 0.0 2.4e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 CCH58235.1 - 1.8e-16 60.4 0.0 2e-06 28.0 0.0 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCH58235.1 - 1.5e-07 31.5 0.0 0.036 14.1 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase Arf PF00025.21 CCH58235.1 - 3.9e-05 23.2 0.0 0.00019 20.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_1 PF00036.32 CCH58235.1 - 0.0001 21.6 11.4 0.0056 16.1 1.1 3.6 3 0 0 3 3 3 2 EF hand TniB PF05621.11 CCH58235.1 - 0.00011 21.6 0.0 0.00057 19.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 CCH58235.1 - 0.00013 22.4 0.0 0.14 12.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 CCH58235.1 - 0.00018 21.1 0.1 15 5.1 0.0 4.1 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.6 CCH58235.1 - 0.00021 21.6 2.2 0.25 11.8 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.23 CCH58235.1 - 0.00038 20.5 0.0 0.26 11.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CCH58235.1 - 0.0014 18.6 1.3 0.28 11.1 0.1 4.0 3 1 2 5 5 5 1 RsgA GTPase RNA_helicase PF00910.22 CCH58235.1 - 0.003 17.9 0.1 5.5 7.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_22 PF13401.6 CCH58235.1 - 0.011 16.0 0.0 10 6.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CCH58235.1 - 0.019 14.5 0.2 17 4.9 0.0 4.0 5 0 0 5 5 5 0 Ferrous iron transport protein B AAA_15 PF13175.6 CCH58235.1 - 0.02 14.7 2.5 1.5 8.5 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 CCH58235.1 - 0.022 14.0 0.0 0.48 9.6 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_18 PF13238.6 CCH58235.1 - 0.025 15.1 0.0 0.67 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCH58235.1 - 0.042 13.6 0.0 6.5 6.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CCH58235.1 - 0.042 14.4 0.0 6.4 7.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter MCM PF00493.23 CCH58235.1 - 0.065 12.3 0.3 5.6 6.0 0.1 2.5 3 0 0 3 3 2 0 MCM P-loop domain AAA_7 PF12775.7 CCH58235.1 - 0.066 12.7 0.0 4.7 6.7 0.1 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CCH58235.1 - 0.067 13.4 0.0 24 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCH58235.1 - 0.08 12.7 0.0 6.5 6.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 CCH58235.1 - 0.14 11.3 0.0 5.9 6.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) EF-hand_8 PF13833.6 CCH58235.1 - 0.28 11.1 7.8 1.3 9.0 0.8 3.0 3 0 0 3 3 2 0 EF-hand domain pair EF-hand_6 PF13405.6 CCH58235.1 - 0.42 10.7 12.2 0.4 10.7 2.0 3.0 3 0 0 3 3 2 0 EF-hand domain EF-hand_5 PF13202.6 CCH58235.1 - 3.1 7.5 12.8 0.085 12.4 2.6 3.1 3 0 0 3 3 3 0 EF hand PKcGMP_CC PF16808.5 CCH58236.1 - 0.03 14.2 0.8 0.03 14.2 0.8 6.1 4 2 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BolA PF01722.18 CCH58237.1 - 6.1e-12 45.6 0.0 1.2e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein PDEase_I PF00233.19 CCH58238.1 - 8.3e-49 166.5 9.2 1.6e-48 165.5 9.2 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SAM_2 PF07647.17 CCH58239.1 - 1.4e-07 31.5 0.0 3.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCH58239.1 - 0.00014 22.2 0.1 0.00032 21.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) COPIIcoated_ERV PF07970.12 CCH58240.1 - 2.1e-76 256.7 0.2 2.5e-76 256.4 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCH58240.1 - 2.6e-24 85.4 0.0 4.7e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.11 CCH58241.1 - 3.3e-36 123.4 0.8 8.8e-36 122.0 0.3 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 CCH58241.1 - 8.5e-32 110.9 5.4 8.5e-32 110.9 5.4 2.3 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 CCH58241.1 - 9.8e-30 103.3 1.4 2.7e-29 101.9 1.4 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 CCH58241.1 - 2e-07 30.8 0.2 1.1e-06 28.4 0.2 2.3 1 0 0 1 1 1 1 PB1 domain Il2rg PF15874.5 CCH58241.1 - 0.0036 17.5 0.4 0.28 11.5 0.1 2.8 2 0 0 2 2 2 1 Putative Interleukin 2 receptor, gamma chain GCS PF03074.16 CCH58241.1 - 0.0065 15.9 0.2 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase PH PF00169.29 CCH58241.1 - 0.082 13.4 1.0 0.33 11.5 1.0 2.2 1 1 0 1 1 1 0 PH domain tRNA-synt_2c PF01411.19 CCH58242.1 - 0.11 11.0 1.6 0.2 10.1 1.6 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (A) Cyclin_N PF00134.23 CCH58243.1 - 4.5e-25 87.8 2.4 1.6e-24 86.0 1.5 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain PUL PF08324.11 CCH58243.1 - 0.002 17.4 0.1 0.0047 16.2 0.1 1.6 1 1 0 1 1 1 1 PUL domain DUF4808 PF16066.5 CCH58243.1 - 0.43 11.1 3.8 2.1 8.9 3.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) HEAT PF02985.22 CCH58244.1 - 0.0081 16.3 1.1 3.3 8.2 0.1 4.6 4 0 0 4 4 4 1 HEAT repeat Skp1_POZ PF03931.15 CCH58244.1 - 0.024 14.8 1.2 0.57 10.4 0.1 3.7 4 0 0 4 4 4 0 Skp1 family, tetramerisation domain PK PF00224.21 CCH58245.1 - 1.5e-166 553.5 2.7 2.1e-166 553.1 2.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CCH58245.1 - 1e-34 119.3 0.0 3.7e-34 117.5 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CCH58245.1 - 1.6e-05 24.2 0.6 3.7e-05 23.0 0.2 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Mtd_N PF18454.1 CCH58245.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Major tropism determinant N-terminal domain IMS PF00817.20 CCH58246.1 - 4.1e-29 101.5 0.1 1.2e-28 100.0 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family BRCT_2 PF16589.5 CCH58246.1 - 6.2e-11 42.6 0.0 2.1e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 CCH58246.1 - 1.3e-10 42.0 0.0 3.7e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.7 CCH58246.1 - 1.3e-07 31.4 0.0 3.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CCH58246.1 - 8.4e-07 29.3 0.1 5e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mCpol PF18182.1 CCH58246.1 - 0.045 14.1 0.3 0.14 12.5 0.0 2.0 2 0 0 2 2 2 0 minimal CRISPR polymerase domain tRNA-synt_2d PF01409.20 CCH58247.1 - 1.1e-90 303.4 0.0 1.4e-90 303.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CCH58247.1 - 9e-16 57.9 3.8 2.4e-15 56.6 0.9 2.8 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CCH58247.1 - 6.1e-09 35.6 0.0 7.3e-06 25.6 0.0 2.5 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 CCH58247.1 - 1.5e-08 34.4 2.4 1.5e-08 34.4 2.4 2.1 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 CCH58247.1 - 3e-05 23.3 0.0 0.00086 18.5 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CCH58247.1 - 0.00046 20.2 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RQC PF09382.10 CCH58247.1 - 0.038 13.8 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 RQC domain YjhX_toxin PF09857.9 CCH58247.1 - 0.11 12.5 0.0 0.45 10.5 0.0 2.0 1 0 0 1 1 1 0 Putative toxin of bacterial toxin-antitoxin pair DUF465 PF04325.13 CCH58247.1 - 0.5 10.4 2.4 1.3 9.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DNApol3-delta_C PF09115.10 CCH58248.1 - 0.075 13.6 0.1 1.2 9.6 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal RPA43_OB PF17875.1 CCH58249.1 - 2.6e-28 99.1 0.2 2.6e-28 99.1 0.2 1.7 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CCH58249.1 - 9.1e-11 42.0 0.0 1.7e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF4859 PF16151.5 CCH58249.1 - 0.012 15.4 0.3 0.028 14.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) SWIRM PF04433.17 CCH58250.1 - 9.2e-10 38.7 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Glyco_transf_24 PF18404.1 CCH58251.1 - 1.5e-34 119.6 3.4 3.8e-34 118.3 3.4 1.7 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CCH58251.1 - 5.8e-16 59.2 0.7 4e-15 56.5 0.0 2.8 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CCH58251.1 - 0.00037 20.4 1.3 0.0013 18.6 1.3 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Stealth_CR2 PF11380.8 CCH58251.1 - 0.0054 16.9 1.6 0.022 14.9 0.2 2.5 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 VWA PF00092.28 CCH58251.1 - 0.23 11.7 2.1 0.96 9.7 0.1 3.0 3 0 0 3 3 3 0 von Willebrand factor type A domain tRNA-synt_2c PF01411.19 CCH58252.1 - 3.1e-222 739.0 0.1 1.9e-221 736.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CCH58252.1 - 1.4e-18 66.7 0.2 3.6e-18 65.4 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CCH58252.1 - 2.7e-14 53.8 2.4 5.7e-14 52.7 2.4 1.6 1 0 0 1 1 1 1 DHHA1 domain AF0941-like PF14591.6 CCH58252.1 - 0.31 11.6 3.2 2.7 8.6 0.1 2.6 2 0 0 2 2 2 0 AF0941-like Synaptobrevin PF00957.21 CCH58254.1 - 4e-32 109.9 1.0 4.5e-32 109.7 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin MCU PF04678.13 CCH58254.1 - 0.1 12.7 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Orf78 PF06024.12 CCH58254.1 - 0.14 12.5 0.8 0.19 12.1 0.8 1.3 1 1 0 1 1 1 0 Orf78 (ac78) Hph PF13694.6 CCH58255.1 - 3.9e-58 196.8 18.5 3.9e-58 196.8 18.5 3.1 3 0 0 3 3 3 1 Sec63/Sec62 complex-interacting family Prefoldin_2 PF01920.20 CCH58255.1 - 5.7 6.9 12.9 0.23 11.4 6.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF5344 PF17279.2 CCH58255.1 - 6.1 7.5 11.5 0.88 10.2 0.2 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5344) PhoLip_ATPase_C PF16212.5 CCH58256.1 - 1.1e-84 284.2 28.6 1.1e-84 284.2 28.6 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCH58256.1 - 1.1e-23 82.7 5.8 3.3e-23 81.1 5.8 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CCH58256.1 - 1.1e-10 42.2 0.2 3.3e-05 24.3 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH58256.1 - 7.1e-09 35.6 0.0 2.4e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CCH58256.1 - 4.2e-07 29.7 0.0 9.6e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCH58256.1 - 0.004 16.9 2.0 0.018 14.8 0.0 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Phg_2220_C PF09524.10 CCH58256.1 - 0.011 15.8 0.5 0.49 10.5 0.0 2.8 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) DUF3069 PF11269.8 CCH58256.1 - 0.13 12.5 0.6 4.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3069) Mt_ATP-synt_B PF05405.14 CCH58256.1 - 0.5 10.0 2.4 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) LDB19 PF13002.7 CCH58257.1 - 1.7e-73 246.5 1.6 3.9e-73 245.3 1.6 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like Tnp_zf-ribbon_2 PF13842.6 CCH58257.1 - 0.17 12.7 2.4 1.1 10.1 0.1 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon PMT PF02366.18 CCH58258.1 - 9.6e-93 310.3 21.1 9.6e-93 310.3 21.1 2.0 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCH58258.1 - 1.2e-57 194.8 13.5 1.2e-57 194.8 13.5 2.7 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCH58258.1 - 6.2e-29 101.2 0.5 1.1e-28 100.3 0.5 1.3 1 0 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.18 CCH58259.1 - 4.5e-53 180.6 24.4 5e-39 134.5 10.6 3.0 1 1 2 3 3 3 2 Nucleoside transporter Exo_endo_phos PF03372.23 CCH58260.1 - 9.4e-25 87.5 0.0 2.3e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CCH58260.1 - 3e-14 52.5 8.4 1.8e-08 34.0 2.4 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CCH58260.1 - 1.1e-10 41.6 14.2 8.3e-07 29.2 2.6 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) RskA PF10099.9 CCH58260.1 - 0.034 14.5 0.0 0.034 14.5 0.0 3.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA RsmF_methylt_CI PF17126.5 CCH58260.1 - 0.11 12.6 0.1 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 CCH58260.1 - 0.3 11.2 2.4 2.2 8.5 0.2 2.8 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 CCH58260.1 - 5.2 8.0 14.7 1.5 9.7 0.1 4.8 5 1 0 5 5 5 0 Leucine Rich Repeat RCC1 PF00415.18 CCH58261.1 - 3.3e-23 82.1 6.4 2e-06 28.3 0.0 6.9 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCH58261.1 - 2.8e-13 49.3 17.7 1.7e-06 27.6 0.2 6.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.23 CCH58262.1 - 7.1e-60 202.6 0.1 1.1e-59 201.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH58262.1 - 3.1e-20 72.6 2.6 1.2e-17 64.3 0.4 3.4 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCH58262.1 - 1.3e-12 48.0 0.2 1.5e-11 44.6 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCH58262.1 - 5.9e-06 26.2 0.0 1.6e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCH58262.1 - 2.4e-05 23.7 0.3 5.6e-05 22.5 0.3 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 CCH58262.1 - 0.0031 17.7 0.7 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif GSH_synth_ATP PF03917.17 CCH58263.1 - 2.4e-131 438.0 0.0 2.8e-131 437.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CCH58263.1 - 1.2e-31 109.2 1.7 1.2e-31 109.2 0.3 1.8 2 0 0 2 2 2 1 Eukaryotic glutathione synthase EI24 PF07264.11 CCH58264.1 - 0.00015 22.1 15.8 0.00031 21.0 15.3 1.8 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Pkinase PF00069.25 CCH58265.1 - 8.2e-62 208.9 0.1 1.8e-61 207.8 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58265.1 - 5.8e-22 78.2 0.0 9.6e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58265.1 - 2.6e-08 33.5 0.0 4.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.7 CCH58265.1 - 0.00037 20.7 0.2 0.0034 17.6 0.0 2.8 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 CCH58265.1 - 0.007 16.4 0.0 3.9 7.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold APH PF01636.23 CCH58265.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCH58265.1 - 0.021 13.6 0.0 0.021 13.6 0.0 2.3 3 0 0 3 3 3 0 Fungal protein kinase FTA2 PF13095.6 CCH58265.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCH58265.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCH58265.1 - 0.067 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Oxidored_FMN PF00724.20 CCH58266.1 - 1.7e-64 218.3 0.0 2e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HhH-GPD PF00730.25 CCH58267.1 - 4.5e-24 85.0 0.0 8.7e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CCH58267.1 - 2.2e-05 24.1 0.0 5.6e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CCH58267.1 - 0.089 13.4 0.0 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain RRM_1 PF00076.22 CCH58268.1 - 1.3e-17 63.3 3.5 2.9e-13 49.4 0.1 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH58268.1 - 0.0002 21.4 1.0 0.31 11.2 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif Spo7_2_N PF15407.6 CCH58268.1 - 0.0087 15.7 0.0 0.18 11.5 0.0 3.0 2 0 0 2 2 2 1 Sporulation protein family 7 RRM_occluded PF16842.5 CCH58268.1 - 0.026 14.4 0.1 5.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Ribosomal_S19 PF00203.21 CCH58269.1 - 5.3e-33 112.8 0.1 8.2e-33 112.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 CCH58270.1 - 1.6e-25 89.5 15.6 1.9e-25 89.3 15.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 CCH58270.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain TMEM247 PF15444.6 CCH58270.1 - 0.29 11.2 2.6 0.34 10.9 2.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 SIL1 PF16782.5 CCH58271.1 - 3e-92 308.9 12.8 3e-92 308.9 12.8 1.7 2 0 0 2 2 2 1 Nucleotide exchange factor SIL1 Acetyltransf_10 PF13673.7 CCH58272.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain B56 PF01603.20 CCH58273.1 - 1.9e-171 570.6 12.1 3.7e-171 569.7 12.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CH_2 PF06294.11 CCH58273.1 - 0.066 13.3 0.8 0.2 11.8 0.8 1.8 1 0 0 1 1 1 0 CH-like domain in sperm protein EMP24_GP25L PF01105.24 CCH58274.1 - 4.4e-30 105.0 0.0 5.5e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TP6A_N PF04406.14 CCH58275.1 - 4.5e-12 45.8 0.7 9.7e-12 44.7 0.7 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase PQ-loop PF04193.14 CCH58276.1 - 8.2e-12 44.7 15.5 5.4e-11 42.1 1.9 3.7 3 1 1 4 4 4 2 PQ loop repeat KleE PF17394.2 CCH58276.1 - 2.6 8.3 8.8 0.45 10.7 4.3 2.0 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein ARD PF03079.14 CCH58277.1 - 9.6e-45 152.6 1.3 1.2e-44 152.3 1.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CCH58277.1 - 1.1e-10 41.0 0.0 1.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CCH58277.1 - 2.7e-05 24.1 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CCH58277.1 - 3.7e-05 23.4 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 CCH58277.1 - 0.019 14.7 0.0 0.024 14.3 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain JmjC PF02373.22 CCH58277.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.8 1 1 1 2 2 2 0 JmjC domain, hydroxylase SdrG_C_C PF10425.9 CCH58277.1 - 0.13 12.3 1.8 0.28 11.3 0.3 1.8 1 1 1 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin Nuc_rec_co-act PF08815.10 CCH58277.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear receptor coactivator Glyco_hydro_72 PF03198.14 CCH58278.1 - 5.2e-145 482.6 7.7 6.7e-145 482.2 7.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CCH58278.1 - 0.00099 18.6 0.2 0.0076 15.7 0.1 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Nop14 PF04147.12 CCH58278.1 - 0.046 11.9 9.6 0.064 11.5 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family Lys PF00062.20 CCH58278.1 - 0.17 12.2 0.4 19 5.5 0.1 2.5 2 0 0 2 2 2 0 C-type lysozyme/alpha-lactalbumin family PNISR PF15996.5 CCH58278.1 - 1.4 9.2 9.5 2.2 8.5 9.5 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF572 PF04502.13 CCH58278.1 - 5.7 6.5 11.2 8.7 5.9 11.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SDA1 PF05285.12 CCH58278.1 - 7 6.0 14.5 8.8 5.6 14.5 1.1 1 0 0 1 1 1 0 SDA1 Utp14 PF04615.13 CCH58278.1 - 7 5.1 14.0 9.3 4.7 14.0 1.1 1 0 0 1 1 1 0 Utp14 protein bZIP_1 PF00170.21 CCH58279.1 - 0.00012 22.2 11.2 0.00012 22.2 11.2 2.7 2 1 0 2 2 2 1 bZIP transcription factor Adaptin_binding PF10199.9 CCH58279.1 - 1.6 9.3 12.8 2.1 9.0 8.9 2.2 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 bZIP_2 PF07716.15 CCH58279.1 - 9.8 6.4 14.7 0.056 13.5 4.3 2.5 3 0 0 3 3 3 0 Basic region leucine zipper LETM1 PF07766.13 CCH58280.1 - 3.6e-93 311.8 6.1 3.6e-93 311.8 6.1 1.6 2 0 0 2 2 2 1 LETM1-like protein TOM13 PF08219.11 CCH58281.1 - 7.7e-17 61.1 0.0 1.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Outer membrane protein TOM13 Sugar_tr PF00083.24 CCH58284.1 - 3.6e-165 550.2 34.9 4.1e-165 550.0 34.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58284.1 - 2.4e-31 109.0 22.6 2.4e-31 109.0 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CCH58284.1 - 0.00019 20.2 6.7 0.00019 20.2 6.7 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 CCH58284.1 - 0.007 14.8 5.9 0.0085 14.5 2.2 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector ATP1G1_PLM_MAT8 PF02038.16 CCH58284.1 - 0.028 13.8 1.9 1 8.9 0.4 3.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1772 PF08592.11 CCH58284.1 - 0.15 12.4 6.5 1.1 9.5 4.1 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) PALP PF00291.25 CCH58285.1 - 2.6e-59 201.1 0.0 2.9e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_transf_28 PF03033.20 CCH58285.1 - 0.16 12.0 0.0 0.75 9.8 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain HgmA PF04209.13 CCH58286.1 - 0.017 13.8 1.0 0.021 13.5 0.1 1.6 2 0 0 2 2 2 0 homogentisate 1,2-dioxygenase KH_8 PF17903.1 CCH58287.1 - 1.7e-30 104.9 0.1 4.4e-30 103.6 0.1 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain Pfg27 PF09216.10 CCH58287.1 - 0.035 13.9 0.1 0.035 13.9 0.1 1.8 2 0 0 2 2 2 0 Pfg27 KH_1 PF00013.29 CCH58287.1 - 0.038 13.8 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF543 PF04418.12 CCH58289.1 - 5.6e-31 106.3 0.2 6.6e-31 106.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) PEX11 PF05648.14 CCH58290.1 - 3.9e-06 26.5 0.9 5e-06 26.1 0.9 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Plug_translocon PF10559.9 CCH58290.1 - 0.085 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p DUF3658 PF12395.8 CCH58291.1 - 0.074 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function MT-A70 PF05063.14 CCH58292.1 - 1e-11 45.1 0.7 3.7e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 MT-A70 ATP_transf PF09830.9 CCH58294.1 - 1.2e-19 70.2 0.0 2.2e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CCH58294.1 - 0.0036 16.7 0.0 0.0056 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) HIT PF01230.23 CCH58294.1 - 0.0036 18.0 0.0 0.0088 16.8 0.0 1.6 1 0 0 1 1 1 1 HIT domain DUF4922 PF16269.5 CCH58294.1 - 0.005 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4922) Pmp3 PF01679.17 CCH58295.1 - 2.7e-19 69.1 5.2 3.2e-19 68.9 5.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CoatB PF10389.9 CCH58296.1 - 4.1 7.3 13.1 0.28 11.1 5.9 2.2 2 0 0 2 2 2 0 Bacteriophage coat protein B Thioredoxin PF00085.20 CCH58297.1 - 1.1e-58 195.6 0.8 2.2e-29 101.5 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CCH58297.1 - 4e-25 88.8 11.4 4e-18 66.0 7.0 4.0 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CCH58297.1 - 7.9e-08 32.7 1.8 0.0067 16.9 0.1 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CCH58297.1 - 1e-06 28.8 0.1 0.11 12.7 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CCH58297.1 - 1.2e-06 28.8 1.2 0.098 13.0 0.1 5.2 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 CCH58297.1 - 1.6e-06 27.7 0.0 0.0019 17.6 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CCH58297.1 - 0.00018 21.4 0.1 0.16 11.9 0.0 2.9 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_9 PF14595.6 CCH58297.1 - 0.025 14.3 4.6 1.9 8.3 0.0 3.8 4 0 0 4 4 4 0 Thioredoxin zf-CCCH_7 PF18586.1 CCH58297.1 - 0.032 14.6 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Redoxin PF08534.10 CCH58297.1 - 0.036 13.8 0.1 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Redoxin DSBA PF01323.20 CCH58297.1 - 0.11 12.2 0.7 4 7.2 0.0 3.4 2 2 1 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CCH58297.1 - 0.45 10.7 5.0 12 6.0 0.8 4.0 3 2 1 4 4 4 0 Thioredoxin Hexokinase_2 PF03727.16 CCH58298.1 - 2.8e-76 256.1 0.0 3.7e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCH58298.1 - 8.4e-71 238.0 0.0 7.4e-70 234.9 0.0 2.0 2 0 0 2 2 2 1 Hexokinase ATG22 PF11700.8 CCH58299.1 - 1.4e-156 521.9 29.0 1.6e-156 521.7 29.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like La PF05383.17 CCH58300.1 - 7.9e-17 61.1 0.1 2.4e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 La domain LAP1C PF05609.12 CCH58300.1 - 6.2 5.8 35.4 7.9 5.5 34.5 1.6 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Glutaredoxin PF00462.24 CCH58301.1 - 6.9e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GAT PF03127.14 CCH58302.1 - 8.7e-05 22.8 1.8 0.01 16.1 0.0 3.4 3 0 0 3 3 3 1 GAT domain IFRD PF05004.13 CCH58302.1 - 0.0015 17.7 0.5 0.0037 16.4 0.5 1.6 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) RRM_Rrp7 PF17799.1 CCH58303.1 - 3.7e-43 147.1 3.0 7.5e-43 146.1 3.0 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 CCH58303.1 - 5.7e-25 87.8 12.2 5.8e-25 87.7 9.1 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 CCH58303.1 - 0.00027 21.2 0.2 0.00027 21.2 0.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF5093) Lipin_mid PF16876.5 CCH58303.1 - 0.026 14.7 0.3 0.075 13.2 0.3 1.8 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF547 PF04784.14 CCH58303.1 - 0.075 13.1 0.7 0.18 11.9 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF547 Complex1_LYR_2 PF13233.6 CCH58304.1 - 7.9e-19 68.2 0.6 1.2e-18 67.6 0.6 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CCH58304.1 - 2.9e-11 43.3 0.4 1.3e-10 41.2 0.1 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) SH3_2 PF07653.17 CCH58305.1 - 0.00078 19.1 0.6 0.0066 16.1 0.6 2.5 1 1 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCH58305.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain DUF4448 PF14610.6 CCH58305.1 - 0.046 13.5 0.0 0.19 11.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SH3_1 PF00018.28 CCH58305.1 - 0.069 12.8 0.0 0.33 10.6 0.0 2.2 1 1 1 2 2 2 0 SH3 domain Orf78 PF06024.12 CCH58305.1 - 0.13 12.6 0.9 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Orf78 (ac78) SKG6 PF08693.10 CCH58305.1 - 0.21 11.0 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nitroreductase PF00881.24 CCH58306.1 - 0.0065 16.5 0.1 0.02 15.0 0.1 1.8 1 1 0 1 1 1 1 Nitroreductase family Cnn_1N PF07989.11 CCH58307.1 - 0.36 11.0 14.3 0.19 11.9 8.2 3.0 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 LMBR1 PF04791.16 CCH58307.1 - 2.6 6.9 10.7 3.3 6.5 10.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Nitroreductase PF00881.24 CCH58308.1 - 7.8e-06 26.0 0.0 1.9e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.24 CCH58309.1 - 0.00024 21.2 0.1 0.001 19.1 0.1 1.8 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.24 CCH58310.1 - 2.8e-11 43.8 0.0 3.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YukD PF08817.10 CCH58310.1 - 0.05 14.3 0.1 1.9 9.3 0.0 2.4 2 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD AA_permease PF00324.21 CCH58311.1 - 3.7e-125 418.2 34.5 4.4e-125 418.0 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH58311.1 - 2.1e-34 119.1 35.6 2.6e-34 118.8 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.13 CCH58311.1 - 0.24 11.4 3.3 0.18 11.8 0.8 2.0 2 0 0 2 2 2 0 Colicin immunity protein AA_permease PF00324.21 CCH58312.1 - 2.3e-125 418.9 32.3 2.6e-125 418.7 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH58312.1 - 1e-33 116.8 34.3 1.2e-33 116.6 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease CnrY PF17524.2 CCH58312.1 - 0.17 12.2 1.4 3.3 8.0 0.1 2.7 2 0 0 2 2 2 0 Anti-sigma factor CnrY Colicin_im PF03857.13 CCH58312.1 - 1.8 8.6 7.1 0.16 11.9 1.0 2.3 3 0 0 3 3 3 0 Colicin immunity protein PSP1 PF04468.12 CCH58313.1 - 5.9e-39 132.2 2.6 5.9e-39 132.2 2.6 2.3 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Spt20 PF12090.8 CCH58313.1 - 0.00014 21.6 9.2 0.00014 21.6 9.2 2.5 3 0 0 3 3 3 1 Spt20 family SARAF PF06682.12 CCH58313.1 - 0.034 13.8 8.9 0.053 13.2 8.9 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CCH58313.1 - 0.26 12.3 4.3 0.73 10.8 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 CCH58313.1 - 0.26 11.2 8.1 0.54 10.2 8.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CNDH2_M PF16869.5 CCH58313.1 - 1.8 9.3 9.5 0.34 11.6 5.0 2.2 2 0 0 2 2 2 0 PF16858 Roughex PF06020.11 CCH58313.1 - 3.5 6.6 6.8 5.4 6.0 6.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PBP PF01161.20 CCH58314.1 - 4.6e-19 69.0 0.1 6e-19 68.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PAP2 PF01569.21 CCH58315.1 - 3.6e-24 85.1 0.6 3.6e-24 85.1 0.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CCH58315.1 - 0.00049 19.8 0.4 0.00049 19.8 0.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CCH58315.1 - 0.00078 19.9 1.7 0.00078 19.9 1.7 3.0 3 0 0 3 3 3 1 PAP2 superfamily C-terminal FUSC_2 PF13515.6 CCH58315.1 - 0.04 14.0 0.2 0.04 14.0 0.2 2.2 3 0 0 3 3 3 0 Fusaric acid resistance protein-like Vta1 PF04652.16 CCH58316.1 - 2.1e-32 112.1 0.1 5.2e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CCH58316.1 - 1.1e-13 50.7 0.2 2.2e-13 49.6 0.2 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain FHA PF00498.26 CCH58317.1 - 8.3e-06 26.1 0.3 2.9e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 FHA domain Phytase PF02333.15 CCH58317.1 - 0.015 14.2 0.2 0.026 13.5 0.2 1.3 1 0 0 1 1 1 0 Phytase Polysacc_deac_3 PF15421.6 CCH58317.1 - 0.033 12.7 0.3 0.16 10.4 0.0 2.2 2 0 0 2 2 2 0 Putative polysaccharide deacetylase DUF2203 PF09969.9 CCH58317.1 - 0.43 11.3 1.3 1.4 9.6 1.3 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Ribosomal_L37e PF01907.19 CCH58318.1 - 1.1e-28 99.2 11.4 1.8e-28 98.4 11.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CCH58318.1 - 0.0038 17.2 1.7 0.0053 16.8 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 CCH58318.1 - 0.089 12.2 2.4 0.17 11.3 2.4 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF1258 PF06869.12 CCH58318.1 - 0.44 10.0 4.7 0.31 10.5 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) LCD1 PF09798.9 CCH58319.1 - 2.6e-128 429.2 54.1 3.2e-128 428.9 54.1 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein Epsilon_antitox PF08998.11 CCH58319.1 - 0.007 16.6 2.1 0.048 13.9 2.1 2.5 1 0 0 1 1 1 1 Bacterial epsilon antitoxin Jnk-SapK_ap_N PF09744.9 CCH58319.1 - 2.4 8.4 12.8 0.14 12.4 6.6 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 PCRF PF03462.18 CCH58319.1 - 4.7 7.0 6.7 17 5.2 6.7 1.9 1 0 0 1 1 1 0 PCRF domain EMG1 PF03587.14 CCH58320.1 - 2.9e-77 258.7 0.0 3.4e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TMEM220 PF15071.6 CCH58321.1 - 0.0043 17.8 1.2 0.013 16.2 0.1 2.5 3 0 0 3 3 3 1 Transmembrane family 220, helix FAM209 PF15206.6 CCH58321.1 - 0.069 12.9 0.4 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 FAM209 family Pox_A14 PF05767.12 CCH58321.1 - 0.35 11.1 11.3 9.3 6.5 0.7 3.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Fib_alpha PF08702.10 CCH58321.1 - 0.93 9.7 4.9 3.5 7.8 0.1 3.5 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Sigma_reg_N PF13800.6 CCH58321.1 - 7.3 7.0 14.8 0.7 10.2 0.3 4.0 4 0 0 4 4 4 0 Sigma factor regulator N-terminal PH PF00169.29 CCH58322.1 - 2.6e-08 34.3 6.0 1.5e-06 28.7 0.4 3.2 3 0 0 3 3 3 2 PH domain ABC_membrane PF00664.23 CCH58323.1 - 7.6e-56 189.8 3.0 9.9e-56 189.4 3.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCH58323.1 - 2.2e-33 115.7 0.0 6.2e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCH58323.1 - 9.8e-09 35.0 0.0 1.4e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 CCH58323.1 - 0.00026 21.5 0.0 0.091 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCH58323.1 - 0.00045 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCH58323.1 - 0.0049 16.7 2.9 0.33 10.7 0.3 3.0 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CCH58323.1 - 0.0052 17.1 0.0 0.059 13.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH58323.1 - 0.0071 16.7 0.0 0.017 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCH58323.1 - 0.011 15.8 0.2 4.2 7.5 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF87 PF01935.17 CCH58323.1 - 0.02 15.0 0.9 0.056 13.5 0.0 2.2 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_5 PF07728.14 CCH58323.1 - 0.023 14.7 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DmsC PF04976.12 CCH58323.1 - 0.024 14.1 0.5 0.062 12.8 0.5 1.6 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) AAA_23 PF13476.6 CCH58323.1 - 0.027 15.0 0.1 0.027 15.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain DUF4116 PF13475.6 CCH58323.1 - 0.039 13.7 0.2 7.1 6.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) RsgA_GTPase PF03193.16 CCH58323.1 - 0.079 12.9 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 CCH58323.1 - 0.13 12.0 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCH58323.1 - 0.15 11.8 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Abhydrolase_1 PF00561.20 CCH58324.1 - 3.3e-67 226.9 0.1 5.6e-67 226.1 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCH58324.1 - 0.0001 23.0 0.4 0.00017 22.3 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_28 PF03033.20 CCH58325.1 - 2.7e-31 108.5 0.0 6.7e-31 107.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CCH58325.1 - 7.7e-23 80.5 5.8 1.8e-13 50.4 0.0 4.0 2 1 0 2 2 2 2 GRAM domain UDPGT PF00201.18 CCH58325.1 - 7.9e-08 31.5 0.0 1.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 CCH58325.1 - 2.3e-07 31.3 0.8 8.5e-07 29.4 0.8 2.1 1 0 0 1 1 1 1 PH domain Glyco_transf_4 PF13439.6 CCH58325.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PH_11 PF15413.6 CCH58325.1 - 4.2 7.8 9.8 0.12 12.9 0.6 3.2 3 0 0 3 3 3 0 Pleckstrin homology domain Exo_endo_phos PF03372.23 CCH58326.1 - 1.3e-13 51.0 0.0 1.9e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Wzy_C PF04932.15 CCH58326.1 - 0.02 14.6 0.1 0.096 12.3 0.2 1.9 2 0 0 2 2 2 0 O-Antigen ligase MARVEL PF01284.23 CCH58326.1 - 0.027 14.5 0.4 0.045 13.8 0.4 1.3 1 0 0 1 1 1 0 Membrane-associating domain Spindle_Spc25 PF08234.12 CCH58327.1 - 1e-10 41.7 2.0 1e-10 41.7 2.0 3.7 3 2 1 4 4 3 1 Chromosome segregation protein Spc25 Spc24 PF08286.11 CCH58327.1 - 2.9e-05 24.3 19.8 0.00022 21.4 7.9 2.5 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 DivIC PF04977.15 CCH58327.1 - 0.0026 17.5 4.3 0.0026 17.5 4.3 2.8 2 1 1 3 3 2 1 Septum formation initiator Spc7 PF08317.11 CCH58327.1 - 0.0034 16.3 12.3 0.0052 15.7 12.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.9 CCH58327.1 - 0.0044 16.1 15.7 0.0075 15.3 15.7 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 CHASE3 PF05227.13 CCH58327.1 - 0.0045 16.9 2.1 0.0072 16.2 2.1 1.3 1 0 0 1 1 1 1 CHASE3 domain ATG16 PF08614.11 CCH58327.1 - 0.011 16.0 9.0 0.018 15.2 9.0 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) YlqD PF11068.8 CCH58327.1 - 0.022 15.1 9.4 0.058 13.8 9.4 1.8 1 0 0 1 1 1 0 YlqD protein PspA_IM30 PF04012.12 CCH58327.1 - 0.034 13.7 4.4 0.041 13.5 3.5 1.5 1 1 1 2 2 2 0 PspA/IM30 family TMF_TATA_bd PF12325.8 CCH58327.1 - 0.036 14.3 7.8 0.072 13.3 7.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Mitofilin PF09731.9 CCH58327.1 - 0.039 12.8 9.6 0.058 12.2 9.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3450 PF11932.8 CCH58327.1 - 0.041 13.2 7.2 0.07 12.4 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CALCOCO1 PF07888.11 CCH58327.1 - 0.041 12.7 10.4 0.057 12.3 10.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2730 PF10805.8 CCH58327.1 - 0.05 13.7 2.2 0.1 12.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SlyX PF04102.12 CCH58327.1 - 0.099 13.3 6.5 0.22 12.1 3.2 2.7 1 1 1 2 2 2 0 SlyX Jnk-SapK_ap_N PF09744.9 CCH58327.1 - 0.11 12.7 9.2 0.19 12.0 9.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FliJ PF02050.16 CCH58327.1 - 0.12 12.6 11.3 0.1 12.9 8.6 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4795 PF16043.5 CCH58327.1 - 0.25 10.9 13.0 2.4 7.7 7.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) KASH_CCD PF14662.6 CCH58327.1 - 0.26 11.1 18.1 2 8.2 1.6 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CCH58327.1 - 0.28 11.2 13.4 5.1 7.1 12.6 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LRRFIP PF09738.9 CCH58327.1 - 0.31 10.5 11.7 0.4 10.1 11.7 1.3 1 0 0 1 1 1 0 LRRFIP family SHE3 PF17078.5 CCH58327.1 - 0.43 10.3 27.7 0.045 13.5 14.6 2.7 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 NAD_binding_6 PF08030.12 CCH58327.1 - 0.44 10.7 7.5 1.2 9.2 3.8 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain CLZ PF16526.5 CCH58327.1 - 0.63 10.4 11.9 1.5 9.2 1.3 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 CCH58327.1 - 0.84 10.3 17.2 1.9 9.2 10.2 2.9 1 1 2 3 3 3 0 Initiation control protein YabA Occludin_ELL PF07303.13 CCH58327.1 - 0.95 10.2 12.1 0.5 11.1 7.9 2.4 2 1 0 2 2 2 0 Occludin homology domain DUF4407 PF14362.6 CCH58327.1 - 1.1 8.5 8.0 2.9 7.2 8.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 CCH58327.1 - 1.2 9.5 8.4 5.7 7.3 0.4 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 CCH58327.1 - 1.4 9.0 12.5 8.4 6.6 1.8 2.7 1 1 1 2 2 2 0 bZIP transcription factor DUF1664 PF07889.12 CCH58327.1 - 1.6 8.8 9.8 3.6 7.7 7.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GrpE PF01025.19 CCH58327.1 - 1.7 8.3 12.7 1.2 8.8 8.2 2.5 1 1 1 2 2 2 0 GrpE Syntaxin-6_N PF09177.11 CCH58327.1 - 1.7 9.2 7.7 3.6 8.2 4.7 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.6 CCH58327.1 - 2 8.4 18.0 1.6 8.7 15.5 2.2 1 1 1 2 2 2 0 FlxA-like protein TMPIT PF07851.13 CCH58327.1 - 3 7.0 14.9 2.4 7.3 6.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein MRPL52 PF18699.1 CCH58327.1 - 3.9 7.7 8.9 5.9 7.2 5.3 2.3 1 1 1 2 2 2 0 Mitoribosomal protein mL52 APG6_N PF17675.1 CCH58327.1 - 5.5 7.5 16.0 1.5 9.3 12.0 2.2 2 1 0 2 2 1 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 CCH58327.1 - 6.1 7.5 12.1 5.5 7.7 9.6 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DHR10 PF18595.1 CCH58327.1 - 8.9 6.4 14.4 4.3 7.4 4.9 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Per1 PF04080.13 CCH58328.1 - 8.4e-86 287.9 13.0 1.1e-85 287.5 13.0 1.1 1 0 0 1 1 1 1 Per1-like family HCO3_cotransp PF00955.21 CCH58329.1 - 8.2e-77 259.1 17.2 7.5e-42 143.8 4.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family 2-Hacid_dh_C PF02826.19 CCH58331.1 - 3.5e-54 182.8 0.0 6.9e-54 181.9 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCH58331.1 - 2.9e-15 56.1 0.0 4.6e-15 55.5 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.12 CCH58331.1 - 1.1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_2 PF03446.15 CCH58331.1 - 2.2e-06 27.9 0.0 3.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CCH58331.1 - 0.0055 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CCH58331.1 - 0.0073 16.4 0.0 0.058 13.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 CCH58331.1 - 0.054 13.6 0.0 0.39 10.8 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 CCH58331.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family Peptidase_M1 PF01433.20 CCH58332.1 - 3.7e-05 23.4 0.0 0.009 15.6 0.0 2.7 2 0 0 2 2 2 2 Peptidase family M1 domain Sad1_UNC PF07738.13 CCH58333.1 - 3.1e-29 101.7 0.1 8.6e-29 100.2 0.1 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal KRAP_IP3R_bind PF14722.6 CCH58333.1 - 0.00048 19.9 0.1 0.0016 18.2 0.1 1.9 1 0 0 1 1 1 1 Ki-ras-induced actin-interacting protein-IP3R-interacting domain zf-CCCH_6 PF18585.1 CCH58333.1 - 0.075 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Peptidase_S8 PF00082.22 CCH58334.1 - 3.8e-08 33.0 0.0 1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Subtilase family TIMELESS PF04821.14 CCH58335.1 - 3.2e-86 289.1 6.8 9e-86 287.6 6.8 1.9 1 0 0 1 1 1 1 Timeless protein Sec2p PF06428.11 CCH58336.1 - 5.4e-28 96.8 15.8 5.4e-28 96.8 15.8 3.7 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p ArfGap PF01412.18 CCH58336.1 - 0.00034 20.7 2.6 0.0013 18.8 0.0 3.1 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf FH2 PF02181.23 CCH58337.1 - 2.6e-88 296.7 11.5 2.6e-88 296.7 11.5 5.2 5 1 2 7 7 7 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CCH58337.1 - 2.4e-37 128.5 4.5 2.4e-37 128.5 4.5 4.8 6 0 0 6 6 6 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 CCH58337.1 - 2.7e-25 89.0 10.2 1.5e-21 76.8 1.9 6.3 6 1 1 7 7 7 2 Diaphanous GTPase-binding Domain AA_permease PF00324.21 CCH58338.1 - 6.7e-136 453.7 46.4 8.1e-136 453.4 46.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH58338.1 - 5.8e-28 97.9 49.6 8.4e-28 97.3 49.6 1.2 1 0 0 1 1 1 1 Amino acid permease TMIE PF16038.5 CCH58338.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 TMIE protein AA_permease PF00324.21 CCH58339.1 - 3.9e-134 447.8 48.3 4.5e-134 447.6 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH58339.1 - 6.6e-32 110.9 50.3 9e-32 110.4 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.8 CCH58339.1 - 0.24 11.0 1.0 25 4.6 0.1 3.3 2 0 0 2 2 2 0 Intrinsic membrane protein PufX Tmemb_55A PF09788.9 CCH58339.1 - 0.58 9.2 2.2 1.7 7.7 2.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 55A PI3_PI4_kinase PF00454.27 CCH58340.1 - 4.7e-33 115.0 0.1 3e-32 112.4 0.1 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CCH58340.1 - 5.3e-17 61.5 0.2 1.9e-16 59.7 0.2 2.1 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 CCH58340.1 - 4.4e-06 26.2 2.8 9.9e-06 25.1 2.8 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CI-B14_5a PF07347.12 CCH58340.1 - 0.1 12.5 0.4 0.39 10.6 0.4 2.0 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Tam41_Mmp37 PF09139.11 CCH58341.1 - 8.7e-88 294.8 9.2 9.5e-81 271.7 2.9 2.0 1 1 0 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial Ist1 PF03398.14 CCH58342.1 - 3e-40 137.8 3.1 2.5e-23 82.8 4.0 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway TPR_2 PF07719.17 CCH58343.1 - 2.8e-14 52.0 16.0 0.0005 20.0 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH58343.1 - 1.6e-12 46.5 13.3 0.00011 22.1 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCH58343.1 - 2.8e-12 45.9 12.8 0.0002 21.0 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCH58343.1 - 9.2e-11 41.7 0.6 0.23 12.2 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH58343.1 - 2.6e-07 30.9 14.7 0.039 14.2 0.1 6.6 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CCH58343.1 - 2.6e-07 30.5 11.5 0.19 12.2 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH58343.1 - 8.6e-07 29.4 2.2 0.052 14.1 0.0 5.5 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH58343.1 - 1.5e-06 28.5 0.9 26 6.0 0.0 7.0 5 1 2 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCH58343.1 - 3e-06 27.3 0.0 0.95 9.7 0.0 4.3 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CCH58343.1 - 3.2e-06 26.6 0.1 0.036 13.3 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH58343.1 - 1.8e-05 24.8 7.9 0.28 11.4 0.1 5.3 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CCH58343.1 - 9.9e-05 22.9 3.0 0.34 11.6 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH58343.1 - 0.0036 17.2 10.4 2.6 8.3 0.0 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat YL1 PF05764.13 CCH58343.1 - 0.0075 16.4 10.2 0.0075 16.4 10.2 3.8 3 1 0 3 3 2 1 YL1 nuclear protein TPR_11 PF13414.6 CCH58343.1 - 0.04 13.6 0.1 0.04 13.6 0.1 5.2 5 1 1 6 6 6 0 TPR repeat MCC-bdg_PDZ PF10506.9 CCH58343.1 - 0.13 12.3 2.5 0.23 11.5 0.6 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TPR_10 PF13374.6 CCH58343.1 - 0.2 11.6 6.7 12 5.9 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CCH58343.1 - 1.8 8.7 5.0 1.7 8.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Dynamin_N PF00350.23 CCH58343.1 - 3.9 7.5 8.5 7.7 6.5 0.3 3.2 3 0 0 3 3 3 0 Dynamin family UFD1 PF03152.14 CCH58344.1 - 2.9e-71 238.5 0.1 4.1e-71 238.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NPR3 PF03666.13 CCH58344.1 - 0.02 13.7 0.6 0.035 12.9 0.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1232 PF06803.12 CCH58344.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) ArAE_2_N PF10337.9 CCH58345.1 - 2.3e-46 158.9 15.2 9.3e-45 153.5 7.6 3.6 3 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CCH58345.1 - 7.8e-13 48.6 8.5 7.8e-13 48.6 8.5 3.2 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 CCH58345.1 - 0.003 16.5 14.6 0.046 12.5 5.4 3.3 2 2 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 CCH58345.1 - 0.021 14.6 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 CCH58346.1 - 2.8e-46 158.5 9.4 2.8e-46 158.5 9.4 3.6 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CCH58346.1 - 7.1e-13 48.8 9.3 7.1e-13 48.8 9.3 3.1 2 2 0 2 2 2 1 Fusaric acid resistance protein-like T2SSS_2 PF16549.5 CCH58346.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS) pilotin, S protein ArAE_2 PF10334.9 CCH58346.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 DUF2953 PF11167.8 CCH58346.1 - 0.06 13.4 0.4 0.97 9.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) ArAE_2_N PF10337.9 CCH58347.1 - 4.2e-53 181.1 5.4 1.3e-50 172.8 1.9 3.1 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CCH58347.1 - 4.9e-13 49.3 11.2 4.9e-13 49.3 11.2 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CCH58347.1 - 5.7e-05 23.1 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ACR_tran PF00873.19 CCH58347.1 - 0.024 12.3 0.3 0.041 11.5 0.3 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF2953 PF11167.8 CCH58347.1 - 0.19 11.9 2.4 0.8 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) CRAL_TRIO PF00650.20 CCH58348.1 - 1.2e-37 129.1 0.0 1.7e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH58348.1 - 5.6e-17 61.7 2.9 1.1e-16 60.8 1.9 2.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain SPRY PF00622.28 CCH58348.1 - 0.034 14.2 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 SPRY domain CRAL_TRIO_2 PF13716.6 CCH58348.1 - 0.042 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DnaJ PF00226.31 CCH58349.1 - 3.1e-18 65.7 0.4 6.6e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain YIF1 PF03878.15 CCH58350.1 - 8.2e-78 261.2 7.4 8.2e-78 261.2 7.4 1.4 2 0 0 2 2 2 1 YIF1 DUF1744 PF08490.12 CCH58351.1 - 2.5e-135 451.1 5.0 3.9e-135 450.5 5.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CCH58351.1 - 4.8e-76 256.1 6.0 4.8e-76 256.1 6.0 2.8 3 1 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CCH58351.1 - 7.5e-18 64.5 6.5 1.3e-14 53.8 3.4 3.5 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CCH58351.1 - 4.7e-07 29.7 0.8 4.5e-06 26.5 0.8 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CCH58351.1 - 0.00012 22.2 2.7 0.00045 20.3 0.0 3.4 4 0 0 4 4 4 1 RNase_H superfamily APP_N PF02177.16 CCH58351.1 - 0.0054 17.1 0.7 0.21 12.0 0.4 3.0 2 0 0 2 2 2 1 Amyloid A4 N-terminal heparin-binding NAPRTase_C PF17956.1 CCH58351.1 - 0.014 15.8 0.0 0.058 13.8 0.0 2.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain ORC5_C PF14630.6 CCH58352.1 - 2.7e-61 207.6 0.6 3.3e-61 207.3 0.6 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CCH58352.1 - 6e-08 33.3 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH58352.1 - 0.00028 21.2 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain CRAL_TRIO_2 PF13716.6 CCH58352.1 - 0.0046 17.1 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TniB PF05621.11 CCH58352.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ResIII PF04851.15 CCH58352.1 - 0.097 12.7 0.6 0.3 11.1 0.0 2.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit GYF PF02213.16 CCH58353.1 - 2.2e-11 43.2 4.5 4.7e-11 42.2 4.5 1.6 1 0 0 1 1 1 1 GYF domain CNOT11 PF10155.9 CCH58353.1 - 0.006 16.7 0.4 0.014 15.6 0.4 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 PH_8 PF15409.6 CCH58353.1 - 0.025 14.9 1.1 0.077 13.3 1.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3748 PF12566.8 CCH58353.1 - 1.2 9.1 3.9 7 6.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3748) Yae1_N PF09811.9 CCH58354.1 - 4.5e-08 32.6 3.9 4.5e-08 32.6 3.9 2.5 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Baculo_p24 PF05073.12 CCH58354.1 - 0.006 16.4 3.3 0.0083 15.9 3.3 1.2 1 0 0 1 1 1 1 Baculovirus P24 capsid protein Dsl1_N PF11988.8 CCH58355.1 - 2.2e-122 408.4 32.0 2.2e-122 408.4 32.0 2.3 3 1 0 3 3 3 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.8 CCH58355.1 - 5.8e-69 231.7 15.9 5.8e-69 231.7 15.9 3.3 2 1 1 3 3 3 1 Retrograde transport protein Dsl1 C terminal VASt PF16016.5 CCH58356.1 - 2.9e-11 44.0 0.6 1.3e-10 41.9 0.6 2.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CCH58356.1 - 7.6e-10 38.9 1.9 7.7e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 CCH58356.1 - 4.3e-07 30.4 2.4 6.9e-07 29.7 0.2 2.6 2 0 0 2 2 2 1 PH domain PGAP1 PF07819.13 CCH58357.1 - 7.5e-09 35.6 1.1 4.3e-08 33.2 0.1 2.4 3 0 0 3 3 3 1 PGAP1-like protein Palm_thioest PF02089.15 CCH58357.1 - 1.3e-06 28.4 0.2 1.4e-05 25.0 0.2 2.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CCH58357.1 - 1.3e-06 28.0 0.0 3.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 CCH58357.1 - 1.4e-06 27.8 2.0 8.2e-05 22.0 0.1 3.5 3 1 1 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 CCH58357.1 - 0.00087 18.6 0.8 0.0012 18.1 0.1 1.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 CCH58357.1 - 0.0026 17.4 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.12 CCH58357.1 - 0.018 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_3 PF01494.19 CCH58358.1 - 8.8e-16 58.1 1.4 2e-10 40.5 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CCH58358.1 - 9.9e-05 21.7 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CCH58358.1 - 0.00011 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 CCH58358.1 - 0.0038 16.3 0.2 0.019 14.1 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CCH58358.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CCH58358.1 - 0.14 11.4 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pterin_bind PF00809.22 CCH58359.1 - 8.8e-50 169.6 0.1 8.3e-49 166.5 0.1 2.2 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CCH58359.1 - 1.4e-36 125.4 0.0 5.2e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CCH58359.1 - 1.9e-32 112.1 0.0 7.1e-32 110.2 0.0 2.1 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) zf-CCHC PF00098.23 CCH58360.1 - 1e-52 174.0 52.9 1.8e-08 34.1 2.8 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CCH58360.1 - 9e-13 47.7 40.3 0.013 15.2 0.4 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 CCH58360.1 - 8.4e-10 38.2 37.2 0.11 12.3 0.9 7.1 5 2 2 7 7 7 7 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CCH58360.1 - 3.7e-09 36.4 40.3 0.17 11.9 0.7 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 CCH58360.1 - 3.3e-05 23.6 43.5 0.028 14.2 0.6 6.8 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.6 CCH58360.1 - 0.0013 18.5 44.4 0.0089 15.8 1.4 6.9 7 0 0 7 7 7 3 Zinc knuckle zf-C2H2_10 PF16588.5 CCH58360.1 - 0.038 13.7 2.7 0.038 13.7 2.7 6.5 6 1 1 7 7 7 0 C2H2 zinc-finger TRAF6_Z2 PF18048.1 CCH58360.1 - 0.11 12.6 8.1 32 4.7 0.1 5.3 4 1 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 RTC4 PF14474.6 CCH58361.1 - 2.4e-29 101.9 0.1 7.3e-29 100.4 0.0 1.9 2 0 0 2 2 2 1 RTC4-like domain DUF1828 PF08861.10 CCH58361.1 - 0.1 12.9 1.4 22 5.4 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF1828 WD40 PF00400.32 CCH58362.1 - 8.8e-13 48.5 2.2 3.6e-05 24.4 0.1 6.3 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58362.1 - 3.4e-11 43.3 0.2 1.6 9.1 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 CCH58362.1 - 0.0016 17.1 0.3 0.038 12.6 0.0 2.4 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactonase PF10282.9 CCH58362.1 - 0.0067 15.7 0.0 0.51 9.5 0.0 2.4 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller Hira PF07569.11 CCH58362.1 - 0.05 13.3 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split BET PF17035.5 CCH58362.1 - 0.063 13.4 0.7 0.18 12.0 0.3 1.9 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation WD40_like PF17005.5 CCH58362.1 - 0.084 12.2 5.2 0.17 11.2 0.7 2.4 2 0 0 2 2 2 0 WD40-like domain MRP-L46 PF11788.8 CCH58363.1 - 5.6e-40 136.8 1.1 8.1e-40 136.3 0.6 1.6 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 CTD_bind PF04818.13 CCH58364.1 - 8e-05 23.4 0.0 0.00031 21.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 CCH58364.1 - 0.00037 20.2 0.0 0.0008 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 CCH58364.1 - 0.025 14.2 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 CCH58364.1 - 0.068 13.3 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif AAA_23 PF13476.6 CCH58365.1 - 4.7e-35 121.9 0.7 4.7e-35 121.9 0.7 9.1 2 1 3 5 5 2 1 AAA domain Rad50_zn_hook PF04423.14 CCH58365.1 - 1e-15 57.3 0.6 1e-15 57.3 0.6 6.4 6 0 0 6 6 5 1 Rad50 zinc hook motif AAA_15 PF13175.6 CCH58365.1 - 3.2e-07 30.4 18.0 3.2e-07 30.4 18.0 5.2 1 1 3 4 4 2 2 AAA ATPase domain SbcCD_C PF13558.6 CCH58365.1 - 1.6e-06 28.3 0.1 6.2e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CCH58365.1 - 9e-06 25.3 0.1 9e-06 25.3 0.1 3.9 4 1 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCH58365.1 - 0.00042 20.2 0.0 0.00042 20.2 0.0 6.1 3 2 1 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH58365.1 - 0.0072 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CCH58365.1 - 0.0095 16.3 0.3 0.077 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 CCH58365.1 - 0.042 12.5 0.0 0.042 12.5 0.0 7.8 3 1 4 7 7 7 0 AAA domain ABC_tran PF00005.27 CCH58365.1 - 0.17 12.4 0.0 0.17 12.4 0.0 7.0 4 3 2 6 6 4 0 ABC transporter AAA_19 PF13245.6 CCH58365.1 - 3.4 8.0 6.5 0.81 10.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain MbeD_MobD PF04899.12 CCH58365.1 - 6.5 7.0 18.0 0.88 9.7 1.7 6.1 6 2 0 6 6 6 0 MbeD/MobD like RNA_pol_I_A49 PF06870.12 CCH58366.1 - 7.6e-119 397.0 1.0 9.1e-119 396.7 1.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DnaJ PF00226.31 CCH58367.1 - 8.7e-16 57.8 4.3 6.4e-15 55.0 4.3 2.2 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CCH58367.1 - 1.4e-14 53.6 4.3 2.3e-14 52.9 4.3 1.4 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_12 PF11331.8 CCH58367.1 - 0.063 13.1 0.6 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain LMBR1 PF04791.16 CCH58367.1 - 0.07 12.0 1.1 0.083 11.8 1.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Lar_restr_allev PF14354.6 CCH58367.1 - 0.071 13.5 1.0 0.16 12.3 1.0 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar TPK_B1_binding PF04265.14 CCH58367.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain zinc_ribbon_4 PF13717.6 CCH58367.1 - 0.17 11.8 2.9 12 5.9 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 CCH58367.1 - 0.2 12.0 0.2 0.2 12.0 0.2 1.9 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Abhydrolase_6 PF12697.7 CCH58368.1 - 5e-06 27.3 0.0 8.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CCH58368.1 - 1.1e-05 24.8 0.0 2.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 CCH58368.1 - 6.1e-05 22.8 0.0 0.00023 20.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CCH58368.1 - 6.7e-05 22.7 1.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 CCH58368.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 CCH58368.1 - 0.0012 18.4 0.1 0.0024 17.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 CCH58368.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_1e PF01406.19 CCH58369.1 - 3.5e-142 473.2 0.6 7.2e-142 472.1 0.6 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CCH58369.1 - 5.8e-09 35.2 3.7 7.7e-06 24.9 0.3 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 CCH58369.1 - 0.0018 17.2 0.2 0.005 15.8 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) Disaggr_repeat PF06848.11 CCH58369.1 - 0.008 15.9 2.5 0.0089 15.7 0.4 2.0 2 0 0 2 2 2 1 Disaggregatase related repeat NAP PF00956.18 CCH58370.1 - 6.1e-07 28.9 12.8 5.2e-06 25.8 12.9 2.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Cir_N PF10197.9 CCH58371.1 - 2.3e-09 37.3 9.9 4.9e-09 36.2 9.9 1.6 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 CCH58371.1 - 1.4e-07 32.4 1.5 1.4e-07 32.4 1.5 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor SUI1 PF01253.22 CCH58372.1 - 1.2e-26 93.0 1.8 1.6e-26 92.6 1.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Bromo_TP_like PF17027.5 CCH58372.1 - 0.035 14.2 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Histone-fold protein Mito_carr PF00153.27 CCH58373.1 - 7.3e-55 182.9 0.3 5.8e-17 61.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pex2_Pex12 PF04757.14 CCH58374.1 - 2e-08 34.1 13.3 0.00011 21.9 6.0 2.2 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region Arylesterase PF01731.20 CCH58374.1 - 0.1 12.8 0.2 0.28 11.4 0.2 1.8 1 0 0 1 1 1 0 Arylesterase zf-C3HC4_4 PF15227.6 CCH58374.1 - 2.3 8.5 12.8 6.9 6.9 12.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CCH58374.1 - 5.4 7.0 14.1 9.5 6.2 14.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cnl2_NKP2 PF09447.10 CCH58375.1 - 0.076 13.2 4.5 0.85 9.8 0.3 3.7 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Endonuclease_NS PF01223.23 CCH58376.1 - 3.3e-65 220.1 0.0 4.1e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Fungal_trans PF04082.18 CCH58378.1 - 2.1e-20 72.9 11.6 2.1e-20 72.9 11.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH58378.1 - 4.4e-08 33.1 10.0 8e-08 32.3 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tir_receptor_C PF07489.11 CCH58378.1 - 1.4 8.8 5.8 3 7.8 5.8 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Zn_clus PF00172.18 CCH58379.1 - 9.6e-05 22.4 11.9 0.00017 21.7 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-H PF05837.12 CCH58379.1 - 0.05 14.0 0.4 0.13 12.6 0.4 1.8 1 0 0 1 1 1 0 Centromere protein H (CENP-H) NCE101 PF11654.8 CCH58380.1 - 1.9e-13 49.9 0.1 2.3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 dCache_2 PF08269.11 CCH58380.1 - 0.019 14.2 0.0 0.019 14.2 0.0 1.0 1 0 0 1 1 1 0 Cache domain RNase_H2_suC PF08615.11 CCH58381.1 - 5.2e-10 39.7 1.0 2.6e-07 30.9 0.5 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FleQ PF06490.11 CCH58381.1 - 0.081 13.3 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ CIF PF16374.5 CCH58381.1 - 0.087 12.9 0.3 0.11 12.6 0.3 1.2 1 0 0 1 1 1 0 Cycle inhibiting factor (CIF) DUF5099 PF17025.5 CCH58382.1 - 0.021 15.2 0.0 0.056 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) KAR9 PF08580.10 CCH58382.1 - 0.063 11.8 3.3 0.096 11.2 3.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Arf PF00025.21 CCH58383.1 - 1.6e-77 258.9 0.0 1.8e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCH58383.1 - 1.4e-14 54.3 0.1 1.9e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCH58383.1 - 3.2e-14 52.9 0.0 3.4e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCH58383.1 - 7.3e-14 51.6 0.0 8.9e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCH58383.1 - 6.1e-12 45.4 1.0 3.7e-08 32.9 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCH58383.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH58383.1 - 2e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCH58383.1 - 0.0081 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CCH58383.1 - 0.04 14.4 0.1 0.076 13.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CCH58383.1 - 0.041 14.0 0.6 0.1 12.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CCH58383.1 - 0.046 13.0 0.2 0.071 12.4 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 CCH58383.1 - 0.053 13.1 0.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 CCH58383.1 - 0.057 12.9 0.1 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCH58383.1 - 0.086 12.7 0.1 10 6.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CCH58383.1 - 0.09 13.3 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CCH58383.1 - 0.15 12.0 0.4 14 5.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CCH58383.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CCH58383.1 - 0.23 11.1 0.5 0.97 9.1 0.3 1.8 2 0 0 2 2 2 0 Thymidylate kinase Metallophos PF00149.28 CCH58384.1 - 1.4e-33 117.1 0.4 2.9e-33 116.1 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mit_KHE1 PF10173.9 CCH58385.1 - 5.4e-56 189.7 6.1 5.4e-56 189.7 6.1 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF4898 PF16239.5 CCH58385.1 - 0.045 13.7 1.1 5.9 6.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) NUMOD3 PF07460.11 CCH58385.1 - 0.11 12.7 1.1 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) Phage_lysis PF03245.13 CCH58385.1 - 0.12 12.5 0.1 1.8 8.7 0.0 2.4 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein Cullin PF00888.22 CCH58386.1 - 8.7e-150 500.3 14.4 1.4e-149 499.6 14.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CCH58386.1 - 1.1e-22 79.9 4.8 1.4e-22 79.5 3.0 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain HMGL-like PF00682.19 CCH58387.1 - 4.5e-82 275.6 0.1 7.9e-82 274.8 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 CCH58387.1 - 0.036 12.9 0.0 4.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Ribosomal_60s PF00428.19 CCH58388.1 - 3.2e-23 82.1 15.9 3.9e-23 81.8 15.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ABC_tran PF00005.27 CCH58390.1 - 4.1e-48 163.4 0.0 4e-25 88.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCH58390.1 - 8.6e-14 51.5 0.0 0.00018 21.0 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCH58390.1 - 1.5e-11 44.7 14.1 0.0088 15.9 1.0 5.5 3 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 CCH58390.1 - 1.2e-08 34.7 3.6 3.4e-08 33.3 3.6 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 CCH58390.1 - 2.2e-07 30.5 0.4 0.02 14.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCH58390.1 - 4.6e-07 29.9 0.0 0.014 15.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH58390.1 - 1.7e-06 28.1 0.1 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CCH58390.1 - 1.8e-06 28.6 0.1 0.00093 19.7 0.0 4.1 5 0 0 5 5 3 2 AAA domain AAA_28 PF13521.6 CCH58390.1 - 2.6e-06 27.8 0.0 0.11 12.7 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.6 CCH58390.1 - 3.4e-05 24.1 0.0 0.28 11.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CCH58390.1 - 0.00041 20.9 0.0 0.61 10.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CCH58390.1 - 0.00048 19.2 0.3 0.67 8.9 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 CCH58390.1 - 0.00052 20.4 0.1 4.1 7.8 0.0 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCH58390.1 - 0.00092 19.6 0.0 3.2 8.2 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 CCH58390.1 - 0.0011 18.6 0.1 0.47 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCH58390.1 - 0.0023 17.9 0.7 1.8 8.5 0.0 3.1 3 0 0 3 3 3 1 NACHT domain DUF87 PF01935.17 CCH58390.1 - 0.0033 17.6 10.1 0.045 13.9 0.1 5.0 5 1 0 5 5 5 1 Helicase HerA, central domain AAA_16 PF13191.6 CCH58390.1 - 0.0034 17.8 0.1 1.1 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CCH58390.1 - 0.0039 16.9 0.2 6.3 6.5 0.2 3.3 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CCH58390.1 - 0.0085 16.3 0.0 6.8 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCH58390.1 - 0.018 14.8 1.5 1.4 8.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 CCH58390.1 - 0.024 14.7 0.0 3.8 7.5 0.0 3.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCH58390.1 - 0.028 13.6 0.1 7.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 CCH58390.1 - 0.03 13.5 0.2 2.6 7.1 0.1 2.9 2 1 0 2 2 2 0 NB-ARC domain Dynamin_N PF00350.23 CCH58390.1 - 0.033 14.3 0.0 2.7 8.0 0.0 3.5 3 0 0 3 3 3 0 Dynamin family NTPase_1 PF03266.15 CCH58390.1 - 0.038 13.9 0.1 7.1 6.5 0.1 3.0 3 0 0 3 3 3 0 NTPase MukB PF04310.12 CCH58390.1 - 0.058 13.2 0.0 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 CCH58390.1 - 0.063 13.3 0.2 10 6.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 CCH58390.1 - 0.073 13.3 0.0 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Thymidylate_kin PF02223.17 CCH58390.1 - 0.13 12.0 0.9 4.1 7.0 0.0 3.5 4 0 0 4 4 3 0 Thymidylate kinase cobW PF02492.19 CCH58390.1 - 0.14 11.7 0.1 33 4.0 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 CCH58390.1 - 1.3 8.7 0.0 0.7 9.5 0.1 4.8 5 2 0 5 5 3 0 AAA ATPase domain MoCF_biosynth PF00994.24 CCH58391.1 - 1.3e-32 112.4 0.0 3.1e-32 111.2 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain Polysacc_synt_4 PF04669.13 CCH58392.1 - 2.2e-19 69.8 0.9 1.4e-17 63.9 0.9 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Phe_ZIP PF08916.11 CCH58392.1 - 0.061 14.0 1.9 2.3 9.0 0.0 2.6 3 0 0 3 3 3 0 Phenylalanine zipper Cation_efflux PF01545.21 CCH58393.1 - 2.6e-41 141.6 12.8 4.1e-41 140.9 12.8 1.3 1 0 0 1 1 1 1 Cation efflux family LMWPc PF01451.21 CCH58394.1 - 1.2e-41 142.4 0.0 1.4e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase GCR1_C PF12550.8 CCH58396.1 - 1.3e-23 83.1 3.1 3.2e-23 81.9 3.1 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes UPF0061 PF02696.14 CCH58397.1 - 2e-106 356.6 1.3 3e-106 356.0 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TRP PF06011.12 CCH58398.1 - 2.9e-116 388.7 38.9 3.6e-116 388.4 38.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCH58398.1 - 8.3e-35 120.2 0.0 1.7e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 ML-like domain TFIIF_alpha PF05793.12 CCH58398.1 - 1.7 7.1 11.0 2.5 6.6 11.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coatomer_WDAD PF04053.14 CCH58399.1 - 5.5e-158 526.7 0.2 9.8e-158 525.8 0.2 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CCH58399.1 - 2.9e-33 113.3 12.5 7.8e-07 29.7 0.1 8.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58399.1 - 2.8e-08 33.9 0.1 7.7 6.9 0.0 6.5 5 3 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CCH58399.1 - 0.00015 21.8 0.0 0.62 10.1 0.0 4.4 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region TPR_2 PF07719.17 CCH58399.1 - 0.0004 20.3 6.8 1.5 9.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Nup160 PF11715.8 CCH58399.1 - 0.0031 16.2 2.3 2.7 6.5 0.0 3.7 3 1 2 5 5 5 2 Nucleoporin Nup120/160 TPR_1 PF00515.28 CCH58399.1 - 0.011 15.5 3.4 9.8 6.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCH58399.1 - 0.013 15.6 0.4 26 5.4 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MetallophosC PF16370.5 CCH58399.1 - 0.031 14.5 0.9 0.28 11.4 0.0 2.9 3 1 1 4 4 4 0 C terminal of Calcineurin-like phosphoesterase FtsJ PF01728.19 CCH58400.1 - 2.3e-50 171.1 0.0 3.5e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CCH58400.1 - 2.8e-05 24.0 0.0 8.3e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH58400.1 - 0.00091 19.0 0.2 1.9 8.3 0.2 2.8 2 1 1 3 3 3 2 Methyltransferase domain Ribosomal_L1 PF00687.21 CCH58401.1 - 2.3e-42 145.0 0.5 2.8e-42 144.8 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.21 CCH58402.1 - 9.3e-67 223.8 0.0 1e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCH58402.1 - 2.3e-09 36.9 0.5 3e-06 26.6 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CCH58402.1 - 1.1e-08 34.9 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCH58402.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CCH58402.1 - 5.5e-07 29.8 0.0 1.5e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCH58402.1 - 4.9e-06 26.6 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCH58402.1 - 0.00012 21.6 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCH58402.1 - 0.0012 18.4 0.1 0.018 14.6 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CCH58402.1 - 0.13 12.1 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RIBIOP_C PF04950.12 CCH58403.1 - 2.6e-88 296.2 0.3 2.6e-88 296.2 0.3 2.4 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCH58403.1 - 1.7e-29 101.7 0.0 8.7e-29 99.5 0.0 2.4 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_33 PF13671.6 CCH58403.1 - 1e-06 29.0 0.0 4.5e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CCH58403.1 - 1.7e-06 27.7 0.0 0.0014 18.2 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CCH58403.1 - 4.8e-06 27.0 0.0 1.3e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH58403.1 - 9.5e-06 25.9 0.1 5.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCH58403.1 - 1.1e-05 25.8 0.0 3.7e-05 24.2 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCH58403.1 - 0.00077 19.5 0.1 0.004 17.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 CCH58403.1 - 0.0012 18.7 0.1 0.0042 17.0 0.1 1.9 1 1 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 CCH58403.1 - 0.0034 16.7 0.2 0.11 11.8 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 CCH58403.1 - 0.0037 17.6 0.0 0.01 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 CCH58403.1 - 0.0043 17.4 0.4 0.011 16.1 0.2 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 CCH58403.1 - 0.0055 16.5 0.1 0.0055 16.5 0.1 4.4 3 2 0 3 3 2 1 AAA domain AAA_28 PF13521.6 CCH58403.1 - 0.0083 16.4 0.0 0.027 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCH58403.1 - 0.01 15.4 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CCH58403.1 - 0.012 16.1 0.0 0.012 16.1 0.0 2.9 4 0 0 4 4 3 0 ABC transporter AAA_30 PF13604.6 CCH58403.1 - 0.016 14.9 1.5 0.022 14.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CCH58403.1 - 0.017 14.3 0.0 0.046 12.9 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 CCH58403.1 - 0.017 14.7 0.2 0.039 13.5 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CCH58403.1 - 0.019 14.9 0.4 0.041 13.8 0.4 1.5 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 CCH58403.1 - 0.019 14.9 0.1 0.05 13.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 CCH58403.1 - 0.025 14.5 1.6 0.058 13.3 0.1 2.5 3 0 0 3 3 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 CCH58403.1 - 0.03 14.8 0.1 0.03 14.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CCH58403.1 - 0.041 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CCH58403.1 - 0.16 11.8 0.0 1.7 8.4 0.0 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HK PF02110.15 CCH58404.1 - 5.2e-85 284.8 0.9 7e-85 284.3 0.9 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CCH58404.1 - 4.6e-57 192.3 0.0 7.4e-57 191.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 CCH58404.1 - 0.13 11.6 1.1 1.5 8.1 0.6 2.7 2 1 0 2 2 2 0 Phosphomethylpyrimidine kinase LRR_9 PF14580.6 CCH58405.1 - 2e-17 63.2 2.5 3.4e-17 62.5 2.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CCH58405.1 - 0.001 19.4 26.7 0.0087 16.5 4.6 4.2 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCH58405.1 - 0.0065 16.2 7.4 0.0065 16.2 7.4 4.2 2 1 2 4 4 4 2 Leucine rich repeat BAH PF01426.18 CCH58406.1 - 2.5e-16 59.6 1.9 3.1e-16 59.3 0.2 2.1 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H_2 PF13832.6 CCH58406.1 - 2.4e-14 53.4 4.7 2.4e-14 53.4 4.7 4.5 3 1 0 3 3 3 1 PHD-zinc-finger like domain PHD PF00628.29 CCH58406.1 - 4.3e-11 42.5 45.4 2.5e-05 24.1 13.3 5.0 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 CCH58406.1 - 2.8e-05 23.6 31.5 8.5e-05 22.0 4.7 5.2 5 0 0 5 5 5 2 PHD-finger PHD_4 PF16866.5 CCH58406.1 - 0.051 13.7 41.9 0.065 13.3 0.5 5.5 5 1 0 5 5 5 0 PHD-finger Cortex-I_coil PF09304.10 CCH58406.1 - 7.3 6.9 7.4 1.8 8.8 3.4 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil PseudoU_synth_1 PF01416.20 CCH58407.1 - 1.2e-11 45.1 0.0 1.2e-10 41.8 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase UPF0113_N PF17833.1 CCH58408.1 - 8.5e-29 100.0 0.1 1.4e-28 99.3 0.1 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CCH58408.1 - 5e-25 87.6 0.0 1.1e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain SRP72 PF08492.12 CCH58409.1 - 4e-10 40.0 7.3 4e-10 40.0 7.3 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 CCH58409.1 - 1.2e-05 25.4 5.4 1.2e-05 25.4 5.4 3.0 3 1 0 3 3 3 1 Putative TPR-like repeat TPR_12 PF13424.6 CCH58409.1 - 0.0019 18.5 3.3 1.9 8.8 0.3 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCH58409.1 - 0.002 18.1 10.3 0.17 12.1 0.9 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH58409.1 - 0.046 14.2 2.3 12 6.5 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCH58409.1 - 0.1 13.5 0.5 56 4.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH58409.1 - 0.4 10.8 4.2 1.3 9.2 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCH58409.1 - 3.9 7.5 9.2 5.8 6.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CCH58410.1 - 1.3e-28 100.0 0.1 3.8e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH58410.1 - 6.9e-19 68.2 0.2 9.3e-18 64.6 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH58410.1 - 1.4e-12 48.0 0.7 5.8e-12 46.0 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CCH58410.1 - 2e-05 23.5 0.0 3.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UTP25 PF06862.12 CCH58410.1 - 0.008 15.0 0.3 2.1 7.1 0.1 2.7 3 0 0 3 3 3 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CCH58410.1 - 0.048 13.9 0.7 1.3 9.3 0.5 2.8 2 1 0 2 2 2 0 AAA domain SET PF00856.28 CCH58411.1 - 1.3e-06 28.9 1.4 2.5e-06 28.0 0.2 2.0 2 0 0 2 2 2 1 SET domain SR-25 PF10500.9 CCH58413.1 - 2 8.0 11.5 0.08 12.5 4.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF676 PF05057.14 CCH58414.1 - 2.1e-51 174.5 0.5 3.2e-51 174.0 0.5 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CCH58414.1 - 8.5e-07 28.9 0.0 2.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CCH58414.1 - 7.8e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase VirJ PF06057.11 CCH58414.1 - 0.056 13.3 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) zf-RING_2 PF13639.6 CCH58416.1 - 0.12 12.7 9.6 0.28 11.6 9.6 1.7 1 0 0 1 1 1 0 Ring finger domain DUF3677 PF12432.8 CCH58416.1 - 1.3 9.4 5.1 8.7 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3677) PHD PF00628.29 CCH58416.1 - 1.5 8.8 7.5 4 7.4 7.5 1.8 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CCH58416.1 - 3.6 7.3 8.7 2.9 7.6 6.9 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CCH58416.1 - 5 7.1 10.6 15 5.6 10.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 6PF2K PF01591.18 CCH58417.1 - 1.4e-61 207.7 1.6 2.3e-61 207.0 1.6 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCH58417.1 - 1.3e-35 122.9 0.0 1.8e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCH58417.1 - 4.4e-05 23.7 0.0 0.00012 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCH58417.1 - 0.0013 18.3 0.2 0.0027 17.2 0.2 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Vps35 PF03635.17 CCH58418.1 - 1e-183 612.7 48.5 7.6e-107 358.6 25.7 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 RecG_N PF17190.4 CCH58418.1 - 0.78 10.5 15.6 3.5 8.4 0.4 5.8 4 2 0 4 4 4 0 RecG N-terminal helical domain HrcA_DNA-bdg PF03444.15 CCH58419.1 - 0.03 14.0 1.2 0.03 14.0 1.2 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Avl9 PF09794.9 CCH58419.1 - 2.7 6.6 8.8 1.7 7.3 1.7 2.0 1 1 1 2 2 2 0 Transport protein Avl9 E2F_CC-MB PF16421.5 CCH58419.1 - 4.9 7.6 8.9 3 8.2 1.0 2.1 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF4050 PF13259.6 CCH58420.1 - 4.9e-07 30.2 2.6 4.9e-07 30.2 2.6 3.6 1 1 0 2 2 2 1 Protein of unknown function (DUF4050) Rxt3 PF08642.10 CCH58421.1 - 1.2e-24 87.5 1.9 1.6e-24 87.1 0.1 2.1 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CCH58421.1 - 0.00096 19.2 0.3 1.9 8.7 0.0 3.3 3 1 1 4 4 4 2 LCCL domain Ribosomal_L31e PF01198.19 CCH58422.1 - 1e-40 137.8 0.7 1.2e-40 137.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Dus PF01207.17 CCH58423.1 - 4.4e-74 249.4 0.0 5.3e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ComA PF02679.15 CCH58423.1 - 0.18 11.2 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) PEP_mutase PF13714.6 CCH58423.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase BRE1 PF08647.11 CCH58424.1 - 5.2e-25 87.3 15.8 5.2e-25 87.3 15.8 6.3 4 3 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CCH58424.1 - 2.8e-07 30.3 10.7 5.2e-07 29.4 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH58424.1 - 4.2e-07 29.7 9.7 7.4e-07 28.9 9.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CCH58424.1 - 1.1e-05 25.3 12.8 2.1e-05 24.4 12.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCH58424.1 - 2.5e-05 24.0 11.9 2.5e-05 24.0 11.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH58424.1 - 0.00017 21.4 14.9 0.00018 21.3 13.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH58424.1 - 0.0037 17.5 11.6 0.007 16.7 11.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CCH58424.1 - 0.022 14.8 10.3 0.061 13.4 10.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 CCH58424.1 - 0.25 11.3 5.1 0.54 10.2 5.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 CCH58424.1 - 0.34 11.4 0.1 0.34 11.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCH58424.1 - 1.4 9.3 7.6 4.2 7.8 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_4 PF14570.6 CCH58424.1 - 9.9 6.1 10.1 19 5.1 10.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Bap31 PF05529.12 CCH58425.1 - 9.5e-38 129.1 0.5 1.2e-37 128.8 0.5 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CCH58425.1 - 0.021 14.8 0.3 0.035 14.1 0.3 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain XPG_I_2 PF12813.7 CCH58425.1 - 0.026 14.0 0.2 0.032 13.7 0.2 1.0 1 0 0 1 1 1 0 XPG domain containing SOGA PF11365.8 CCH58425.1 - 0.031 15.4 0.2 0.054 14.6 0.2 1.4 1 0 0 1 1 1 0 Protein SOGA T2SSM PF04612.12 CCH58425.1 - 0.2 11.7 3.3 2.7 8.1 0.8 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M DUF4083 PF13314.6 CCH58425.1 - 0.38 10.7 1.6 3.2 7.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Bromodomain PF00439.25 CCH58426.1 - 7.2e-36 122.1 9.8 6e-18 64.7 0.9 3.1 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 CCH58426.1 - 8.5e-21 73.9 1.3 4.3e-20 71.6 1.3 2.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DSHCT PF08148.12 CCH58427.1 - 4.9e-50 169.4 0.3 1.2e-49 168.1 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 CCH58427.1 - 7.3e-42 142.4 0.3 5.5e-41 139.5 0.3 2.3 2 0 0 2 2 2 1 Ski2 N-terminal region DEAD PF00270.29 CCH58427.1 - 1.9e-21 76.6 0.1 6.1e-21 75.0 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 CCH58427.1 - 4.7e-15 56.2 8.1 2.2e-14 54.1 8.1 2.2 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CCH58427.1 - 1.2e-07 32.1 0.0 1.2e-06 28.8 0.0 2.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH58427.1 - 1.2e-06 28.6 0.2 5.7e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCH58427.1 - 0.092 13.0 0.1 0.74 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CCH58429.1 - 2.1e-92 306.5 0.0 8.3e-45 152.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH58429.1 - 2.5e-21 75.2 0.1 2.4e-12 46.4 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCH58429.1 - 6.8e-13 48.7 0.0 7e-05 22.6 0.0 3.2 3 1 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCH58429.1 - 1.3e-11 44.9 0.0 0.00016 21.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCH58429.1 - 2.2e-11 44.4 0.1 9e-06 26.2 0.0 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CCH58429.1 - 1.3e-10 41.5 0.0 0.00091 19.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CCH58429.1 - 6.7e-09 35.9 0.0 5.1e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CCH58429.1 - 8.1e-09 35.9 0.7 0.00055 20.2 0.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CCH58429.1 - 4.2e-07 30.2 0.0 0.0032 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCH58429.1 - 1.9e-06 27.4 0.0 0.0059 15.9 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 CCH58429.1 - 4.4e-06 27.0 0.0 0.19 12.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 CCH58429.1 - 1.9e-05 24.7 0.0 0.015 15.2 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CCH58429.1 - 3.7e-05 23.2 0.1 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CCH58429.1 - 0.00011 22.2 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 CCH58429.1 - 0.00017 21.5 0.0 0.0026 17.6 0.0 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 CCH58429.1 - 0.00028 20.8 0.0 0.041 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCH58429.1 - 0.00029 21.1 0.0 0.99 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CCH58429.1 - 0.0006 19.4 0.0 0.86 9.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 CCH58429.1 - 0.0019 17.8 2.5 2.8 7.5 0.0 3.8 2 2 0 4 4 4 1 AAA domain AAA_3 PF07726.11 CCH58429.1 - 0.0044 16.9 0.0 3.3 7.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CCH58429.1 - 0.0051 16.6 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCH58429.1 - 0.0053 17.3 0.1 1.3 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 CCH58429.1 - 0.0056 16.8 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CCH58429.1 - 0.0057 16.4 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 CCH58429.1 - 0.0098 15.6 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CCH58429.1 - 0.01 15.8 0.0 3.5 7.5 0.0 3.2 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CCH58429.1 - 0.014 15.3 0.1 0.16 11.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CCH58429.1 - 0.014 15.9 0.1 0.29 11.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 CCH58429.1 - 0.024 14.3 0.6 0.18 11.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCH58429.1 - 0.029 14.1 0.0 7 6.3 0.0 3.5 2 2 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 CCH58429.1 - 0.035 13.0 0.0 0.14 11.1 0.0 1.9 3 0 0 3 3 3 0 AFG1-like ATPase ATPase PF06745.13 CCH58429.1 - 0.052 12.9 0.1 17 4.6 0.0 3.0 3 0 0 3 3 3 0 KaiC Zeta_toxin PF06414.12 CCH58429.1 - 0.055 12.8 0.1 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin CDC48_N PF02359.18 CCH58429.1 - 0.055 13.7 0.1 0.16 12.2 0.1 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_19 PF13245.6 CCH58429.1 - 0.066 13.6 1.7 0.59 10.5 0.0 2.9 4 0 0 4 4 2 0 AAA domain FSH1 PF03959.13 CCH58430.1 - 0.034 13.8 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COX7C PF02935.16 CCH58431.1 - 8.2e-25 86.8 3.4 9.7e-25 86.6 3.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc RRM_1 PF00076.22 CCH58432.1 - 1.7e-11 43.8 0.1 3.3e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 CCH58432.1 - 0.027 14.7 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 SPA PF08616.10 CCH58433.1 - 5.4e-13 48.9 2.6 5.4e-13 48.9 2.6 3.1 3 0 0 3 3 3 1 Stabilization of polarity axis Afi1 PF07792.12 CCH58433.1 - 0.62 10.5 0.0 0.62 10.5 0.0 5.0 5 2 0 5 5 5 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3306 PF11748.8 CCH58433.1 - 1.2 10.0 6.7 50 4.8 0.8 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3306) TPP_enzyme_N PF02776.18 CCH58434.1 - 6.7e-30 104.0 0.0 1.1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH58434.1 - 2.9e-19 69.2 0.0 5.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH58434.1 - 3.9e-12 46.2 0.0 8.7e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Complex1_LYR PF05347.15 CCH58435.1 - 3.1e-14 52.8 0.3 3.7e-14 52.5 0.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCH58435.1 - 0.039 14.7 0.1 0.046 14.5 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like RhoGAP PF00620.27 CCH58436.1 - 3.2e-43 147.2 1.0 9.2e-43 145.7 1.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CCH58436.1 - 4.4e-12 46.0 25.0 1.9e-06 28.0 10.4 2.5 2 0 0 2 2 2 2 LIM domain ZapB PF06005.12 CCH58436.1 - 0.21 12.1 2.2 0.83 10.1 2.2 2.0 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 CCH58436.1 - 0.3 11.3 5.2 0.79 10.0 1.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper LSM PF01423.22 CCH58437.1 - 6.5e-17 61.0 0.0 7.5e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCH58437.1 - 9.4e-05 22.5 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CCH58437.1 - 0.00041 20.4 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain F1F0-ATPsyn_F PF10791.9 CCH58438.1 - 2e-37 127.5 0.1 2.4e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi UCH PF00443.29 CCH58439.1 - 2.7e-56 190.9 0.1 2.7e-56 190.9 0.1 3.3 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CCH58439.1 - 1e-40 137.5 19.1 3.2e-16 59.0 0.1 5.1 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 CCH58439.1 - 2.1e-05 24.3 14.4 0.00017 21.3 0.2 3.5 4 0 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Col_cuticle_N PF01484.17 CCH58439.1 - 0.016 15.2 0.1 0.064 13.3 0.1 2.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain CHASE5 PF17149.4 CCH58439.1 - 0.037 13.9 0.6 0.29 11.1 0.2 2.8 3 0 0 3 3 3 0 Periplasmic sensor domain found in signal transduction proteins GPP34 PF05719.11 CCH58440.1 - 2e-63 214.2 0.0 2.5e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PUF PF00806.19 CCH58440.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Leucyl-specific PF14795.6 CCH58440.1 - 0.22 11.6 0.5 1.3 9.2 0.2 2.1 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Leo1 PF04004.13 CCH58441.1 - 1.4e-46 158.3 0.3 1.4e-46 158.3 0.3 3.2 3 0 0 3 3 3 1 Leo1-like protein Myb_DNA-bind_2 PF08914.11 CCH58441.1 - 0.0044 17.2 0.5 0.0044 17.2 0.5 2.1 2 0 0 2 2 2 1 Rap1 Myb domain DUF5423 PF17461.2 CCH58441.1 - 7.7 5.3 12.4 0.049 12.5 1.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Profilin PF00235.19 CCH58442.1 - 1.9e-39 134.8 0.0 2.1e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Profilin NTNH_C PF08470.10 CCH58442.1 - 0.24 11.3 0.0 0.3 10.9 0.0 1.1 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Aldo_ket_red PF00248.21 CCH58443.1 - 2.9e-49 167.8 0.1 1e-47 162.8 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kei1 PF08552.11 CCH58444.1 - 7.5e-36 123.8 12.1 3.4e-31 108.6 5.9 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 TLD PF07534.16 CCH58445.1 - 3e-27 95.6 1.6 4.7e-25 88.4 0.7 2.4 2 0 0 2 2 2 2 TLD NUC153 PF08159.12 CCH58446.1 - 2.2e-12 46.6 2.8 2.2e-12 46.6 2.8 3.6 4 0 0 4 4 4 2 NUC153 domain YL1 PF05764.13 CCH58447.1 - 0.0044 17.2 10.2 0.0044 17.2 10.2 1.6 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 CCH58447.1 - 0.074 11.3 7.9 0.095 11.0 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein AT_hook PF02178.19 CCH58447.1 - 0.18 11.8 5.4 0.65 10.1 5.4 2.0 1 0 0 1 1 1 0 AT hook motif Stm1_N PF09598.10 CCH58447.1 - 2.8 8.9 12.6 2.3 9.2 4.8 3.1 3 0 0 3 3 3 0 Stm1 BCIP PF13862.6 CCH58448.1 - 3.5e-49 167.4 0.4 3.5e-49 167.4 0.4 1.6 2 0 0 2 2 2 1 p21-C-terminal region-binding protein DUF2574 PF10836.8 CCH58448.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) VHS PF00790.19 CCH58449.1 - 3.5e-40 137.1 0.7 1.2e-39 135.4 0.0 2.2 2 1 1 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.20 CCH58449.1 - 3.3e-21 75.7 2.3 3.3e-21 75.7 2.3 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CCH58449.1 - 6e-08 32.2 0.1 3.1e-07 29.9 0.1 2.2 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 CCH58449.1 - 6.1e-08 32.9 0.2 6.1e-08 32.9 0.2 3.0 3 0 0 3 3 3 1 GAT domain MnmE_helical PF12631.7 CCH58449.1 - 0.073 13.2 1.3 0.16 12.1 1.3 1.5 1 0 0 1 1 1 0 MnmE helical domain H-kinase_dim PF02895.14 CCH58449.1 - 0.14 12.6 1.9 7.8 7.0 0.0 3.2 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain AP3B1_C PF14796.6 CCH58449.1 - 0.21 11.9 3.3 0.17 12.1 1.3 1.9 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Glycos_transf_3 PF00591.21 CCH58450.1 - 6e-74 248.8 0.0 8.6e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CCH58450.1 - 2.5e-12 46.4 0.0 4.2e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Vac_ImportDeg PF09783.9 CCH58451.1 - 1.3e-59 200.7 2.6 1.8e-59 200.2 2.6 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF3724 PF12521.8 CCH58451.1 - 0.099 12.6 2.0 0.33 10.9 2.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) KilA-N PF04383.13 CCH58451.1 - 0.2 11.5 1.7 0.57 10.0 1.7 1.7 1 1 0 1 1 1 0 KilA-N domain DUF4718 PF15842.5 CCH58451.1 - 0.29 10.9 1.6 0.74 9.6 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) UPF0139 PF03669.13 CCH58452.1 - 5.5e-05 23.0 0.1 0.0025 17.7 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0139) dCMP_cyt_deam_1 PF00383.23 CCH58453.1 - 2.9e-20 72.0 0.0 3.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCH58453.1 - 2.5e-18 66.1 0.0 3.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 CCH58453.1 - 0.00047 20.3 0.1 0.013 15.6 0.1 2.0 1 1 0 1 1 1 1 APOBEC2 SNAD4 PF18750.1 CCH58453.1 - 0.00047 20.3 0.0 0.0011 19.0 0.0 1.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CCH58453.1 - 0.0006 19.9 0.0 0.039 14.0 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 CCH58453.1 - 0.0032 17.5 0.1 0.0054 16.8 0.1 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase NAD2 PF18782.1 CCH58453.1 - 0.012 15.7 0.0 0.14 12.3 0.0 2.0 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 Inv-AAD PF18785.1 CCH58453.1 - 0.032 14.1 1.6 0.71 9.7 1.6 2.7 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 CCH58453.1 - 0.058 13.3 0.1 0.8 9.6 0.0 2.0 1 1 1 2 2 2 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 CCH58453.1 - 0.086 12.8 0.0 0.39 10.7 0.0 1.9 1 1 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase DnaJ PF00226.31 CCH58454.1 - 1.1e-06 28.6 3.7 2.7e-06 27.4 3.7 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4731 PF15875.5 CCH58454.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Mito_carr PF00153.27 CCH58455.1 - 2.1e-56 187.8 0.2 1e-20 73.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 CCH58456.1 - 2e-23 82.4 5.8 3.6e-23 81.5 5.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH58456.1 - 4.7e-17 62.2 0.0 7.2e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCH58456.1 - 2.3e-05 23.8 0.3 4.7e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCH58456.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sec8_exocyst PF04048.14 CCH58457.1 - 1.9e-46 157.5 1.8 1.9e-46 157.5 1.8 3.3 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CCH58457.1 - 7.1e-08 32.1 2.5 1.9e-07 30.7 2.5 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Tfb2_C PF18307.1 CCH58457.1 - 0.015 15.7 0.1 0.08 13.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain DUF5446 PF17522.2 CCH58457.1 - 2.3 8.4 5.0 4.1 7.6 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5446) Pkinase PF00069.25 CCH58458.1 - 1.3e-23 83.8 0.0 2.6e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58458.1 - 6.7e-09 35.4 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 CCH58458.1 - 0.00024 21.1 10.2 10 6.7 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat Kinase-like PF14531.6 CCH58458.1 - 0.00079 18.8 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 CCH58458.1 - 0.026 14.9 0.0 4.7 7.7 0.0 3.6 3 1 1 4 4 4 0 HEAT repeats WD40 PF00400.32 CCH58458.1 - 0.075 13.9 5.8 17 6.5 0.0 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat APH_6_hur PF04655.14 CCH58458.1 - 0.16 11.3 0.1 0.4 10.0 0.1 1.6 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase PF00069.25 CCH58459.1 - 4.2e-62 209.9 0.0 6e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58459.1 - 3.7e-28 98.5 0.0 5.4e-28 98.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH58459.1 - 0.00016 20.7 1.4 0.00032 19.7 1.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Ribosomal_L19 PF01245.20 CCH58460.1 - 5.2e-06 26.4 0.7 8.8e-06 25.6 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 HIG_1_N PF04588.13 CCH58461.1 - 4e-05 23.7 0.2 8.4e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Peptidase_S8 PF00082.22 CCH58462.1 - 5.8e-25 88.2 2.1 1.4e-24 86.9 2.1 1.6 1 1 0 1 1 1 1 Subtilase family Dus PF01207.17 CCH58463.1 - 2.9e-61 207.3 0.0 6.5e-61 206.1 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 CCH58463.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase FMN_dh PF01070.18 CCH58463.1 - 0.2 10.6 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PRK PF00485.18 CCH58464.1 - 7e-63 211.9 0.0 1.2e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CCH58464.1 - 2.5e-32 112.0 0.2 4e-32 111.3 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CCH58464.1 - 7.4e-05 23.3 0.0 0.00037 21.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CCH58464.1 - 0.0012 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CCH58464.1 - 0.0036 17.7 0.3 2.3 8.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain CPT PF07931.12 CCH58464.1 - 0.012 15.5 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CCH58464.1 - 0.027 14.6 0.0 0.052 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CCH58464.1 - 0.14 12.2 0.9 0.82 9.7 0.9 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CoaE PF01121.20 CCH58464.1 - 0.21 11.3 0.9 13 5.4 0.8 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase HA2 PF04408.23 CCH58465.1 - 3.3e-16 59.5 0.0 3.3e-16 59.5 0.0 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCH58465.1 - 2.8e-15 56.6 0.1 2.2e-14 53.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCH58465.1 - 2.9e-11 43.6 0.0 8.8e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCH58465.1 - 5.4e-07 29.5 0.1 1.6e-06 28.0 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH58465.1 - 5.2e-05 23.5 0.2 0.00028 21.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 CCH58465.1 - 0.002 17.2 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CCH58465.1 - 0.0071 16.7 0.6 0.017 15.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH58465.1 - 0.014 15.2 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 CCH58465.1 - 0.014 15.4 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_14 PF13173.6 CCH58465.1 - 0.064 13.3 1.9 0.96 9.5 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCH58465.1 - 0.069 13.5 0.1 0.25 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 CCH58465.1 - 0.087 12.3 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CCH58465.1 - 0.51 10.8 0.0 0.51 10.8 0.0 3.2 3 1 0 3 3 2 0 ABC transporter Glyoxalase PF00903.25 CCH58466.1 - 3.7e-31 108.0 0.0 1.7e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CCH58466.1 - 3.4e-09 37.0 0.0 0.00032 20.9 0.0 3.7 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CCH58466.1 - 0.00024 21.0 2.7 5.4 7.0 0.0 4.1 4 0 0 4 4 4 2 Glyoxalase-like domain CppA_N PF14506.6 CCH58466.1 - 0.00034 20.7 0.0 0.62 10.2 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_6 PF18029.1 CCH58466.1 - 0.015 16.1 0.0 8.2 7.3 0.0 2.7 2 2 0 2 2 2 0 Glyoxalase-like domain DUF4033 PF13225.6 CCH58466.1 - 0.14 12.1 0.1 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4033) Inp1 PF12634.7 CCH58467.1 - 1.6e-34 118.9 0.5 1.6e-34 118.9 0.5 2.2 2 1 0 2 2 2 1 Inheritance of peroxisomes protein 1 ERG2_Sigma1R PF04622.12 CCH58468.1 - 5.9e-95 316.5 0.8 7.2e-95 316.3 0.8 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein pEK499_p136 PF18736.1 CCH58468.1 - 0.00042 20.0 0.0 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 HEPN pEK499 p136 IBN_N PF03810.19 CCH58469.1 - 1.1e-07 31.7 1.9 1.1e-07 31.7 1.9 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Urb2 PF10441.9 CCH58469.1 - 0.024 14.6 3.5 6.1 6.7 0.0 3.6 3 1 0 3 3 3 0 Urb2/Npa2 family MRP-S26 PF14943.6 CCH58470.1 - 0.079 12.9 14.1 0.5 10.3 4.5 2.3 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 LSM PF01423.22 CCH58471.1 - 2e-14 53.0 0.6 2.4e-14 52.8 0.6 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCH58471.1 - 0.014 15.1 0.2 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Hfq protein TRAPPC9-Trs120 PF08626.11 CCH58472.1 - 1.3e-283 943.7 26.1 1.7e-283 943.3 26.1 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 CCH58472.1 - 0.0046 17.2 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat PINIT PF14324.6 CCH58473.1 - 1.3e-37 129.4 2.3 1.3e-37 129.4 2.3 2.2 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 CCH58473.1 - 7e-22 76.9 6.7 1.3e-21 76.1 6.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 CCH58473.1 - 2.5e-10 39.8 0.7 4.5e-10 39.0 0.7 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 CCH58473.1 - 9.1e-05 22.2 0.6 0.00022 21.0 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCH58473.1 - 0.019 15.0 2.4 0.022 14.8 0.3 2.2 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CCH58473.1 - 0.4 10.6 1.6 0.87 9.5 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH58473.1 - 0.6 10.5 2.8 1.2 9.5 2.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 CCH58473.1 - 1.3 9.2 3.8 2.8 8.2 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CCH58473.1 - 2.4 8.1 7.0 1.2 9.0 3.2 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.14 CCH58474.1 - 7.7e-28 96.8 0.9 1.5e-27 95.9 0.9 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CCH58474.1 - 5.2e-13 49.3 3.1 1.3e-12 48.1 3.1 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CCH58474.1 - 7.3e-06 25.7 0.3 8.8e-06 25.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 CCH58474.1 - 0.0019 17.8 0.1 0.0037 16.8 0.1 1.5 1 0 0 1 1 1 1 NnrU protein Rab5ip PF07019.12 CCH58474.1 - 6.8 7.4 12.5 0.12 13.0 3.0 2.6 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) zf-HIT PF04438.16 CCH58475.1 - 0.00024 20.9 8.8 0.0018 18.1 8.6 2.2 2 0 0 2 2 2 1 HIT zinc finger ABC_membrane PF00664.23 CCH58476.1 - 1.5e-41 142.9 29.1 1.4e-32 113.4 21.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCH58476.1 - 1.5e-40 138.9 0.2 1.3e-23 84.1 0.0 3.6 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCH58476.1 - 5.2e-09 35.9 8.7 0.018 14.5 0.8 4.7 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH58476.1 - 1.4e-07 31.1 0.2 0.0021 17.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCH58476.1 - 2e-05 24.5 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CCH58476.1 - 2.2e-05 24.7 1.0 0.76 10.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 CCH58476.1 - 2.7e-05 23.4 0.0 0.0098 15.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 CCH58476.1 - 5.6e-05 23.7 16.6 0.012 16.2 0.2 3.7 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CCH58476.1 - 0.00031 20.6 0.7 0.84 9.4 0.1 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CCH58476.1 - 0.00038 20.5 0.0 0.032 14.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCH58476.1 - 0.00056 20.3 0.1 0.58 10.5 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CCH58476.1 - 0.00065 20.3 0.1 0.75 10.3 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH58476.1 - 0.0011 18.8 0.2 1.2 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CCH58476.1 - 0.0018 18.0 0.3 1.4 8.6 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 CCH58476.1 - 0.0029 17.2 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CCH58476.1 - 0.0098 16.3 0.3 16 5.9 0.0 3.7 4 0 0 4 4 3 0 RNA helicase ATP_bind_1 PF03029.17 CCH58476.1 - 0.012 15.4 0.1 17 5.1 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 CCH58476.1 - 0.016 14.8 0.5 1.3 8.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 CCH58476.1 - 0.016 14.8 2.6 1.1 8.9 0.3 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 CCH58476.1 - 0.051 13.4 0.1 0.78 9.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCH58476.1 - 0.062 13.2 2.2 2.6 7.9 0.2 3.1 4 0 0 4 4 2 0 NTPase APS_kinase PF01583.20 CCH58476.1 - 0.09 12.7 0.4 45 3.9 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase TsaE PF02367.17 CCH58476.1 - 0.12 12.4 0.1 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CCH58476.1 - 0.16 12.4 1.5 1 9.8 0.3 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CCH58476.1 - 0.17 12.1 0.2 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCH58476.1 - 0.31 10.9 6.9 5.9 6.7 0.1 4.1 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CCH58476.1 - 0.34 10.9 2.0 24 4.9 0.1 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Wzy_C PF04932.15 CCH58476.1 - 0.38 10.4 0.0 0.38 10.4 0.0 3.4 3 1 0 3 3 3 0 O-Antigen ligase AAA_19 PF13245.6 CCH58476.1 - 0.53 10.6 1.5 3.9 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCH58476.1 - 0.6 9.8 4.0 12 5.5 0.3 2.8 2 1 0 2 2 2 0 AAA domain Carn_acyltransf PF00755.20 CCH58478.1 - 3.3e-153 511.5 0.0 4e-153 511.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DER1 PF04511.15 CCH58481.1 - 1.7e-23 83.6 1.1 2e-23 83.4 1.1 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_L2_C PF03947.18 CCH58482.1 - 3.6e-51 172.6 0.5 8.1e-51 171.5 0.5 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCH58482.1 - 1.3e-25 89.1 0.2 4.9e-25 87.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.17 CCH58483.1 - 3.7e-28 98.6 0.0 5.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CCH58483.1 - 0.00095 18.9 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Connexin PF00029.19 CCH58483.1 - 0.011 15.5 0.2 0.019 14.7 0.2 1.3 1 0 0 1 1 1 0 Connexin Peptidase_S49_N PF08496.10 CCH58483.1 - 0.29 11.2 2.6 0.61 10.1 2.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EMP24_GP25L PF01105.24 CCH58484.1 - 1.4e-41 142.5 0.0 1.6e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD M16C_assoc PF08367.11 CCH58485.1 - 2.3e-69 233.3 1.6 3.8e-69 232.6 1.6 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CCH58485.1 - 3.3e-26 92.4 0.2 1.4e-18 67.5 0.1 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCH58485.1 - 2.6e-11 43.7 0.0 3.7e-10 40.0 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UBA_4 PF14555.6 CCH58486.1 - 3.3e-11 42.8 0.0 7.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 CCH58486.1 - 8.2e-08 32.3 1.0 0.00015 21.9 0.2 3.5 2 1 0 2 2 2 2 UBX domain ODAPH PF15848.5 CCH58486.1 - 0.026 15.0 1.5 0.054 13.9 0.9 1.8 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein Methyltransf_11 PF08241.12 CCH58487.1 - 1.8e-12 47.7 0.0 3.5e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH58487.1 - 1.1e-09 38.8 0.0 2.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH58487.1 - 1.6e-07 31.3 0.1 1.3e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH58487.1 - 3.2e-06 27.8 0.1 3.2e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH58487.1 - 3.3e-06 27.0 0.1 5.5e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH58487.1 - 0.0076 15.6 0.0 0.053 12.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family TMEM214 PF10151.9 CCH58487.1 - 3.8 5.9 10.7 5.4 5.3 10.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator PIG-S PF10510.9 CCH58488.1 - 1.8e-38 132.7 1.6 2.6e-38 132.1 1.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF577 PF04510.12 CCH58488.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF577) Metallophos PF00149.28 CCH58489.1 - 2.4e-35 122.9 0.1 2.4e-35 122.9 0.1 2.1 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCH58489.1 - 1.4e-17 63.9 0.4 2.9e-17 62.8 0.4 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PIG-P PF08510.12 CCH58490.1 - 8.1e-28 96.8 0.9 9.3e-28 96.6 0.9 1.0 1 0 0 1 1 1 1 PIG-P DUF3341 PF11821.8 CCH58490.1 - 0.14 11.7 0.4 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Zn_clus PF00172.18 CCH58492.1 - 2e-06 27.8 12.4 2e-06 27.8 12.4 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.19 CCH58493.1 - 4.1e-48 162.7 0.5 2.1e-47 160.3 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CCH58493.1 - 1.6e-37 128.3 0.2 1.6e-37 128.3 0.2 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CCH58493.1 - 7.8e-06 26.3 5.4 1.3e-05 25.5 1.3 3.2 3 1 1 4 4 4 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 CCH58493.1 - 2.3e-05 24.6 0.0 7.5e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.32 CCH58493.1 - 0.00025 20.4 0.3 0.0014 18.1 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CCH58493.1 - 0.0028 18.1 0.9 0.023 15.2 0.7 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 CCH58493.1 - 0.014 15.2 0.2 0.041 13.7 0.2 1.9 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 CCH58493.1 - 0.073 12.6 0.1 0.24 11.0 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 CCH58493.1 - 0.12 12.4 1.8 0.32 11.1 0.1 2.7 3 0 0 3 3 3 0 EF-hand domain Ank_2 PF12796.7 CCH58494.1 - 5.1e-10 39.8 0.1 1.7e-05 25.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCH58494.1 - 3.5e-09 36.2 0.7 0.0017 18.7 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CCH58494.1 - 8.3e-07 29.2 0.3 0.0016 18.7 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH58494.1 - 1.2e-05 25.8 0.5 0.00093 19.7 0.0 3.4 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CCH58494.1 - 0.00017 21.9 0.0 0.65 10.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Csm2_III-A PF03750.13 CCH58494.1 - 0.061 14.2 4.1 0.064 14.1 1.0 2.2 2 0 0 2 2 2 0 Csm2 Type III-A Exonuc_VII_L PF02601.15 CCH58494.1 - 0.1 12.1 5.3 0.16 11.5 5.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit A1_Propeptide PF07966.12 CCH58494.1 - 0.25 11.3 1.8 4.1 7.4 0.2 3.0 3 0 0 3 3 3 0 A1 Propeptide GAS PF13851.6 CCH58494.1 - 1.1 8.5 17.7 2.4 7.4 8.6 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MATalpha_HMGbox PF04769.12 CCH58495.1 - 2.8e-12 46.4 0.3 8.2e-12 44.9 0.3 1.7 1 1 1 2 2 2 1 Mating-type protein MAT alpha 1 HMG-box Homeodomain PF00046.29 CCH58496.1 - 2.6e-07 30.4 3.5 2.7e-07 30.3 0.5 2.3 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 CCH58496.1 - 3.2e-06 26.5 0.1 8.2e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CCH58496.1 - 6.1e-06 26.0 1.1 6.1e-06 26.0 1.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain AA_permease PF00324.21 CCH58497.1 - 2.3e-124 415.6 45.8 2.6e-124 415.4 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH58497.1 - 2.2e-25 89.4 48.1 3.1e-25 88.9 48.1 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 CCH58497.1 - 0.5 9.1 0.0 0.5 9.1 0.0 4.8 2 1 1 4 4 4 0 Predicted membrane protein (DUF2207) RrnaAD PF00398.20 CCH58499.1 - 2e-70 236.9 0.0 2.4e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CCH58499.1 - 3.3e-07 30.9 0.0 1.4e-06 28.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH58499.1 - 3.1e-05 24.5 0.0 0.0001 22.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.19 CCH58499.1 - 6.6e-05 22.8 0.0 0.00017 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 CCH58499.1 - 0.0019 18.0 0.2 0.26 11.1 0.0 2.3 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 CCH58499.1 - 0.0035 17.1 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 CCH58499.1 - 0.0068 17.1 0.0 0.021 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH58499.1 - 0.0092 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 CCH58499.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 CCH58499.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CCH58499.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CCH58499.1 - 0.033 14.1 0.0 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_28 PF02636.17 CCH58499.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CCH58499.1 - 0.092 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain AAA_lid_4 PF17864.1 CCH58499.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 RuvB AAA lid domain KAR9 PF08580.10 CCH58501.1 - 6.8e-51 173.7 41.5 9e-51 173.2 40.7 1.4 1 1 0 1 1 1 1 Yeast cortical protein KAR9 SesA PF17107.5 CCH58501.1 - 0.014 15.6 1.1 1.4 9.1 0.8 3.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CAF1C_H4-bd PF12265.8 CCH58502.1 - 1.1e-24 86.5 2.4 2.2e-24 85.5 0.6 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCH58502.1 - 1.1e-16 60.8 2.0 0.00025 21.8 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat SUKH_6 PF14568.6 CCH58502.1 - 0.028 14.8 2.6 0.12 12.8 0.4 3.0 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall CPSF_A PF03178.15 CCH58502.1 - 0.1 11.9 0.0 5.9 6.1 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region Lyase_1 PF00206.20 CCH58503.1 - 1.6e-111 372.7 0.2 2e-111 372.4 0.2 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CCH58503.1 - 1.6e-23 82.9 0.2 1.2e-22 80.1 0.0 2.6 3 0 0 3 3 3 1 Fumarase C C-terminus Rad60-SLD PF11976.8 CCH58504.1 - 7.8e-21 73.7 0.1 9.6e-21 73.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCH58504.1 - 3.8e-13 49.0 0.0 4.5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 CCH58505.1 - 5.3e-73 245.6 0.0 1.5e-72 244.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 CCH58505.1 - 1e-39 134.9 1.2 1e-39 134.9 1.2 2.2 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 CCH58505.1 - 7.7e-36 123.7 0.0 1.8e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58505.1 - 1.8e-05 24.2 0.0 4.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Cyclin PF08613.11 CCH58506.1 - 3.9e-35 121.6 1.1 6.6e-35 120.9 1.1 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CCH58506.1 - 0.00051 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.20 CCH58507.1 - 7.2e-48 162.6 1.0 1.5e-47 161.6 1.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CCH58507.1 - 2.5e-20 72.9 6.4 2e-19 70.1 0.9 2.9 2 0 0 2 2 2 2 PMC2NT (NUC016) domain HRDC PF00570.23 CCH58507.1 - 5e-11 42.4 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Ras PF00071.22 CCH58508.1 - 1.9e-55 186.9 0.2 2.3e-55 186.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH58508.1 - 1.2e-33 115.8 0.1 1.8e-33 115.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH58508.1 - 4.3e-16 58.8 0.0 5.4e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH58508.1 - 6.8e-08 32.1 0.1 8.5e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCH58508.1 - 8.8e-07 28.6 0.2 5.4e-05 22.8 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCH58508.1 - 2.7e-06 27.0 0.1 3.8e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCH58508.1 - 3.9e-06 26.9 0.0 6.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH58508.1 - 0.00022 21.2 0.1 0.035 14.0 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 CCH58508.1 - 0.00046 20.0 0.2 0.009 15.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CCH58508.1 - 0.002 17.9 0.3 0.089 12.5 0.1 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CCH58508.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 CCH58508.1 - 0.007 16.0 0.1 0.027 14.1 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CCH58508.1 - 0.011 16.2 0.1 0.017 15.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CCH58508.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CCH58508.1 - 0.026 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CCH58508.1 - 0.031 14.2 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CCH58508.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CCH58508.1 - 0.074 12.3 0.1 0.18 11.1 0.1 1.6 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 CCH58508.1 - 0.081 12.8 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 CCH58508.1 - 0.13 12.1 0.2 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CCH58508.1 - 0.17 11.9 0.0 0.49 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_membrane PF00664.23 CCH58509.1 - 4.6e-56 190.5 5.6 6.2e-56 190.0 5.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCH58509.1 - 5.1e-33 114.5 0.0 1.1e-32 113.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCH58509.1 - 0.00018 21.0 0.0 0.00037 20.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH58509.1 - 0.0088 15.8 0.1 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH58509.1 - 0.013 15.8 0.0 0.2 11.9 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CCH58509.1 - 0.038 14.4 0.0 0.38 11.2 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCH58509.1 - 0.056 13.4 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCH58509.1 - 0.068 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CCH58509.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_Eps PF04627.13 CCH58510.1 - 1.1e-20 73.4 1.2 1.2e-20 73.2 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_phi PF04931.13 CCH58511.1 - 4.2e-199 663.4 33.2 6e-199 662.9 33.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi Kinesin PF00225.23 CCH58513.1 - 2.9e-93 312.4 18.0 9.6e-62 208.8 8.5 3.7 2 2 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CCH58513.1 - 1e-20 74.2 0.0 1e-20 74.2 0.0 4.3 3 1 1 4 4 4 1 Microtubule binding Ribo_biogen_C PF04034.13 CCH58514.1 - 1.1e-51 173.9 0.0 1.7e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CCH58514.1 - 3.7e-15 55.4 0.1 6.1e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VPS9 PF02204.18 CCH58515.1 - 5.3e-08 33.0 0.6 2.3e-07 30.9 0.6 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 CCH58515.1 - 3.3e-06 27.2 1.1 0.03 14.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH58515.1 - 0.0024 18.2 0.2 2.4 9.0 0.0 4.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 CCH58515.1 - 0.06 13.9 5.2 0.31 11.7 0.3 3.7 2 1 2 4 4 4 0 Ankyrin repeats (3 copies) gerPA PF10676.9 CCH58515.1 - 0.082 13.2 0.2 0.35 11.1 0.2 2.2 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF SGTA_dimer PF16546.5 CCH58516.1 - 1.7e-17 62.9 4.9 1.7e-17 62.9 4.9 2.4 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 CCH58516.1 - 1.5e-12 46.6 3.1 0.0014 18.5 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCH58516.1 - 1.1e-10 40.9 10.4 0.00035 20.3 0.7 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH58516.1 - 9.2e-07 28.6 10.6 0.14 12.4 0.8 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCH58516.1 - 6.8e-06 26.1 8.3 0.025 15.0 0.5 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCH58516.1 - 2e-05 24.3 1.1 1.7 8.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH58516.1 - 3.1e-05 24.2 0.0 0.16 12.3 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCH58516.1 - 3.2e-05 24.5 0.0 0.0071 17.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCH58516.1 - 0.00013 21.6 8.4 0.00047 19.8 0.1 3.9 2 1 2 4 4 4 1 TPR repeat TPR_6 PF13174.6 CCH58516.1 - 0.0012 19.3 0.6 0.86 10.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH58516.1 - 0.005 17.5 0.0 4.2 8.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCH58516.1 - 0.016 15.7 0.1 1.1 9.8 0.1 2.7 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCH58516.1 - 0.2 11.9 0.0 0.75 10.0 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCH58516.1 - 0.2 11.6 0.8 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCH58516.1 - 0.51 10.5 3.0 4 7.6 0.1 3.0 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 CCH58516.1 - 0.67 10.1 3.8 4.5 7.4 0.2 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain GATA PF00320.27 CCH58517.1 - 1.1e-11 44.1 5.0 1.8e-11 43.4 5.0 1.4 1 0 0 1 1 1 1 GATA zinc finger zn-ribbon_14 PF16503.5 CCH58517.1 - 0.2 11.2 3.5 2.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-ribbon Fcf1 PF04900.12 CCH58518.1 - 1.2e-33 115.4 1.1 1.9e-33 114.8 0.3 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CCH58518.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 PIN like domain Peptidase_S8 PF00082.22 CCH58519.1 - 3.6e-33 115.1 7.3 6e-33 114.4 7.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CCH58519.1 - 2.2e-10 41.0 0.0 2.2e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 RXT2_N PF08595.11 CCH58519.1 - 0.0019 18.3 1.6 0.0039 17.2 1.6 1.5 1 0 0 1 1 1 1 RXT2-like, N-terminal AF-4 PF05110.13 CCH58519.1 - 0.0054 14.9 3.2 0.0073 14.5 3.2 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein SARAF PF06682.12 CCH58520.1 - 0.2 11.2 8.3 0.29 10.8 8.3 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis TPR_14 PF13428.6 CCH58520.1 - 3.7 8.6 5.7 1.6 9.8 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_GLY PF01302.25 CCH58521.1 - 4e-14 52.4 0.0 8e-14 51.4 0.0 1.5 2 0 0 2 2 1 1 CAP-Gly domain TACC_C PF05010.14 CCH58521.1 - 0.002 18.0 19.2 0.11 12.3 0.4 2.1 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF641 PF04859.12 CCH58521.1 - 0.002 18.5 1.8 0.002 18.5 1.8 2.8 1 1 1 2 2 1 1 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.5 CCH58521.1 - 0.0048 17.5 3.2 0.0048 17.5 3.2 2.4 1 1 1 2 2 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2151 PF10221.9 CCH58521.1 - 0.0078 14.9 7.4 0.0096 14.6 7.4 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator DUF3987 PF13148.6 CCH58521.1 - 0.025 13.6 4.9 0.041 12.9 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CLIP1_ZNF PF16641.5 CCH58521.1 - 0.041 13.8 0.4 0.066 13.1 0.4 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle MRP-S26 PF14943.6 CCH58521.1 - 0.041 13.8 12.1 0.058 13.3 12.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Allexi_40kDa PF05549.11 CCH58521.1 - 0.064 12.8 12.9 0.075 12.5 12.2 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein HMMR_N PF15905.5 CCH58521.1 - 0.075 12.5 20.3 0.11 12.0 20.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal zf-CCHC PF00098.23 CCH58521.1 - 0.098 12.8 1.6 0.17 12.0 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle RPW8 PF05659.11 CCH58521.1 - 0.11 12.1 2.2 0.18 11.5 2.2 1.4 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fungal_TACC PF12709.7 CCH58521.1 - 0.15 12.5 13.0 0.17 12.4 0.5 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4201 PF13870.6 CCH58521.1 - 0.21 11.3 15.3 0.39 10.4 15.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) zf-C4H2 PF10146.9 CCH58521.1 - 0.21 11.8 13.1 0.3 11.4 13.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein AAA_13 PF13166.6 CCH58521.1 - 0.23 10.1 11.6 0.31 9.7 11.6 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.7 CCH58521.1 - 0.46 10.6 18.7 0.46 10.6 16.7 2.0 1 1 1 2 2 2 0 Tropomyosin like RP-C_C PF11800.8 CCH58521.1 - 1.1 9.4 10.3 1.7 8.7 10.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1664 PF07889.12 CCH58521.1 - 1.1 9.3 8.0 0.18 11.8 4.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 CCH58521.1 - 1.1 8.5 23.1 0.02 14.3 10.2 2.1 1 1 1 2 2 1 0 FAM76 protein Exonuc_VII_L PF02601.15 CCH58521.1 - 1.4 8.4 14.6 2 7.9 14.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 CCH58521.1 - 1.8 7.1 15.9 2.4 6.6 15.6 1.3 1 1 0 1 1 1 0 Macoilin family ALMT PF11744.8 CCH58521.1 - 1.8 7.3 12.6 2.3 6.9 12.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter APG6_N PF17675.1 CCH58521.1 - 3.1 8.3 23.1 5.5 7.5 23.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region HYLS1_C PF15311.6 CCH58521.1 - 3.8 8.3 9.2 9.4 7.1 9.2 1.7 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Phage_HK97_TLTM PF06120.11 CCH58521.1 - 4.1 6.5 11.9 5.8 6.0 11.9 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Presenilin PF01080.17 CCH58521.1 - 4.2 6.0 10.7 5.1 5.8 10.7 1.1 1 0 0 1 1 1 0 Presenilin CCDC53 PF10152.9 CCH58521.1 - 4.7 7.6 14.7 3.7 8.0 12.8 1.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex V_ATPase_I PF01496.19 CCH58521.1 - 7.2 4.4 13.4 9.8 4.0 13.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RA PF00788.23 CCH58522.1 - 4.4e-16 59.3 0.1 7.1e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_Ste50p PF09235.10 CCH58522.1 - 7.2e-10 39.0 4.2 2.7e-09 37.1 4.2 2.0 1 1 0 1 1 1 1 Ste50p, sterile alpha motif SAM_2 PF07647.17 CCH58522.1 - 0.012 15.8 0.6 0.18 12.0 0.1 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF3128 PF11326.8 CCH58523.1 - 1.1e-21 77.0 0.8 1.2e-21 76.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) UPF0203 PF05254.12 CCH58523.1 - 0.07 13.4 2.6 0.24 11.7 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 CCH58523.1 - 0.071 13.3 0.8 0.25 11.5 0.8 1.9 1 1 0 1 1 1 0 CHCH domain SelR PF01641.18 CCH58524.1 - 7.5e-45 151.9 0.0 8.8e-45 151.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.12 CCH58524.1 - 0.0083 15.6 0.8 3.2 7.3 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 CCH58524.1 - 0.023 14.7 0.6 0.48 10.5 0.2 2.2 2 0 0 2 2 2 0 Double zinc ribbon GFA PF04828.14 CCH58524.1 - 0.03 14.6 0.1 1.3 9.4 0.0 2.2 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-B_box PF00643.24 CCH58524.1 - 0.1 12.7 1.7 0.51 10.5 0.1 2.1 2 0 0 2 2 2 0 B-box zinc finger GAT PF03127.14 CCH58525.1 - 5.9e-07 29.7 1.2 2.1e-06 27.9 0.3 2.3 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 CCH58525.1 - 8.2e-06 25.7 1.3 2.3e-05 24.3 0.3 2.2 2 1 1 3 3 3 1 VHS domain Mvb12 PF09452.10 CCH58525.1 - 0.038 14.4 0.1 0.11 13.0 0.1 1.8 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 COMMD1_N PF17221.3 CCH58525.1 - 0.13 12.6 0.4 0.34 11.2 0.1 1.8 2 0 0 2 2 2 0 COMMD1 N-terminal domain V-SNARE PF05008.15 CCH58527.1 - 0.04 14.3 4.0 0.44 11.0 0.5 2.7 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus HTH_50 PF18024.1 CCH58527.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain FtsH_ext PF06480.15 CCH58527.1 - 0.5 10.7 4.3 0.25 11.7 0.2 2.4 2 0 0 2 2 2 0 FtsH Extracellular FAM60A PF15396.6 CCH58527.1 - 5.3 7.0 8.2 11 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein Family FAM60A WD40 PF00400.32 CCH58528.1 - 2.2e-14 53.6 0.8 0.025 15.5 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58528.1 - 1.5e-09 38.1 0.0 0.0014 18.8 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PIG-X PF08320.12 CCH58529.1 - 9.5e-29 100.8 0.0 1.5e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DUF5341 PF17276.2 CCH58530.1 - 1.5e-21 77.2 5.0 2.4e-21 76.6 5.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5341) UCR_14kD PF02271.16 CCH58531.1 - 3.8e-38 129.5 0.4 4.4e-38 129.3 0.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Fumble PF03630.14 CCH58532.1 - 1e-116 389.8 7.2 1.2e-115 386.2 7.2 1.9 1 1 0 1 1 1 1 Fumble DUF3666 PF12408.8 CCH58532.1 - 0.029 13.6 1.1 0.054 12.7 0.2 1.9 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase DUF5643 PF18705.1 CCH58532.1 - 0.085 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Kre28 PF17097.5 CCH58533.1 - 3.6e-16 59.1 37.7 2.5e-14 53.0 27.2 2.1 1 1 1 2 2 2 2 Spindle pole body component LMBR1 PF04791.16 CCH58533.1 - 4.5 6.1 13.0 7.2 5.4 13.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein RPAP1_C PF08620.10 CCH58534.1 - 3.2e-27 94.4 0.1 7.3e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CCH58534.1 - 1.9e-15 56.3 9.2 2.8e-15 55.8 6.5 2.6 2 0 0 2 2 2 1 RPAP1-like, N-terminal DUF3510 PF12022.8 CCH58534.1 - 0.037 14.4 0.1 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) HEAT PF02985.22 CCH58534.1 - 0.15 12.4 0.0 0.57 10.6 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat CM_2 PF01817.21 CCH58534.1 - 0.68 10.3 6.9 0.39 11.1 0.7 3.1 2 1 1 3 3 3 0 Chorismate mutase type II ArfGap PF01412.18 CCH58535.1 - 4.8e-29 100.8 2.6 4.8e-29 100.8 2.6 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.29 CCH58535.1 - 1.2e-09 38.6 0.2 1.3e-08 35.3 0.2 3.0 1 0 0 1 1 1 1 PH domain Abi_HHR PF07815.14 CCH58535.1 - 0.0073 16.4 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Abl-interactor HHR PH_9 PF15410.6 CCH58535.1 - 0.034 14.5 0.3 0.034 14.5 0.3 3.6 3 0 0 3 3 3 0 Pleckstrin homology domain Pkinase PF00069.25 CCH58536.1 - 1.2e-67 228.1 0.0 1.6e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58536.1 - 8.8e-48 162.8 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58536.1 - 6.1e-05 22.5 0.0 0.00037 19.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCH58536.1 - 7.8e-05 21.6 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase LRR_9 PF14580.6 CCH58537.1 - 1.1 8.7 8.5 1.1 8.8 2.8 2.8 2 1 1 3 3 3 0 Leucine-rich repeat LRR_4 PF12799.7 CCH58537.1 - 1.4 9.5 15.4 0.4 11.2 4.1 4.8 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) Presenilin PF01080.17 CCH58537.1 - 3.6 6.3 7.1 5.2 5.7 7.1 1.2 1 0 0 1 1 1 0 Presenilin Zn_clus PF00172.18 CCH58538.1 - 0.00048 20.2 6.0 0.00089 19.3 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApoA-II PF04711.13 CCH58538.1 - 0.037 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) UPF0515 PF15135.6 CCH58538.1 - 0.67 9.3 9.9 1.4 8.2 6.3 2.8 3 0 0 3 3 3 0 Uncharacterised protein UPF0515 CTP_transf_like PF01467.26 CCH58539.1 - 1.9e-09 37.9 0.1 2.6e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like EMC1_C PF07774.13 CCH58540.1 - 4.8e-64 216.0 0.0 9.6e-64 215.0 0.0 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CCH58540.1 - 0.0026 17.4 0.0 0.95 9.0 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain DUF179 PF02622.15 CCH58540.1 - 0.015 15.2 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 HigB-like_toxin PF05015.13 CCH58540.1 - 0.13 12.7 1.2 1.7 9.1 0.0 3.0 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB Mgr1 PF08602.10 CCH58541.1 - 8.2e-166 551.6 6.3 9.5e-166 551.4 6.3 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit GrpE PF01025.19 CCH58541.1 - 0.014 15.1 3.8 0.027 14.1 3.8 1.4 1 0 0 1 1 1 0 GrpE MPM1 PF17234.2 CCH58541.1 - 0.16 12.2 3.6 0.32 11.2 3.6 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Thioredoxin PF00085.20 CCH58542.1 - 1e-28 99.4 1.2 3.5e-16 59.1 0.3 4.3 4 1 1 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 CCH58542.1 - 1.8e-14 54.1 1.6 1.8e-14 54.1 1.6 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain ERp29_N PF07912.13 CCH58542.1 - 0.00037 20.6 0.6 0.003 17.7 0.0 2.6 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_2 PF13098.6 CCH58542.1 - 0.17 12.3 1.6 1.7 9.2 0.1 3.0 3 0 0 3 3 3 0 Thioredoxin-like domain GRASP55_65 PF04495.14 CCH58543.1 - 9.1e-33 113.5 0.0 8.4e-32 110.4 0.0 2.1 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.16 CCH58544.1 - 6.9e-72 241.7 0.0 9.6e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCH58544.1 - 2.1e-62 210.6 0.0 3.3e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Spb1_C PF07780.12 CCH58545.1 - 5.3e-83 277.8 23.6 5.3e-83 277.8 23.6 3.3 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 CCH58545.1 - 1.3e-54 185.0 0.0 2.6e-54 184.0 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CCH58545.1 - 4.8e-45 153.3 20.7 4.8e-45 153.3 20.7 5.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3381) Peptidase_M3 PF01432.20 CCH58546.1 - 5.2e-144 480.9 2.9 9.3e-144 480.1 2.9 1.4 1 0 0 1 1 1 1 Peptidase family M3 DUF2393 PF09624.10 CCH58546.1 - 0.026 14.5 0.4 0.12 12.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) FlgM PF04316.13 CCH58546.1 - 0.074 13.4 0.3 0.73 10.2 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF5040 PF16443.5 CCH58546.1 - 0.34 10.3 5.0 0.19 11.1 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5040) MRC1 PF09444.10 CCH58547.1 - 6.1e-39 133.9 11.8 6.1e-39 133.9 11.8 8.7 8 2 1 9 9 9 1 MRC1-like domain Vac17 PF17321.2 CCH58548.1 - 6.1e-138 461.0 44.4 7e-138 460.8 44.4 1.0 1 0 0 1 1 1 1 Vacuole-related protein 17 MATalpha_HMGbox PF04769.12 CCH58549.1 - 2.8e-12 46.4 0.3 8.2e-12 44.9 0.3 1.7 1 1 1 2 2 2 1 Mating-type protein MAT alpha 1 HMG-box Homeodomain PF00046.29 CCH58550.1 - 3.2e-07 30.1 3.4 4.1e-07 29.8 0.4 2.3 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 CCH58550.1 - 3e-06 26.6 0.1 7.5e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 CCH58550.1 - 4.7e-06 26.4 2.9 5e-06 26.3 1.1 2.1 2 0 0 2 2 2 1 Homeobox KN domain Peroxin-13_N PF04088.13 CCH58551.1 - 1.3e-49 168.2 2.1 2.1e-49 167.6 2.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 CCH58551.1 - 4.1e-07 29.5 0.0 7.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH58551.1 - 4.4e-07 29.7 0.0 8.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH58551.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 CCH58551.1 - 1.9e-05 24.9 0.1 3.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1045 PF06299.12 CCH58551.1 - 0.22 11.5 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) MMR1 PF08505.10 CCH58552.1 - 2.9e-18 67.1 32.9 2.9e-18 67.1 32.9 3.4 2 2 1 3 3 3 1 Mitochondrial Myo2 receptor-related protein LURAP PF14854.6 CCH58552.1 - 0.001 19.0 1.7 0.0017 18.3 0.2 2.1 2 0 0 2 2 2 1 Leucine rich adaptor protein DUF1192 PF06698.11 CCH58552.1 - 0.0095 16.0 0.2 0.026 14.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) bZIP_1 PF00170.21 CCH58552.1 - 0.031 14.4 0.5 0.031 14.4 0.5 3.3 3 0 0 3 3 3 0 bZIP transcription factor ABC_tran_CTD PF16326.5 CCH58552.1 - 0.038 14.2 4.4 0.33 11.2 1.0 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 CCH58552.1 - 0.15 12.5 9.4 0.094 13.1 2.1 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YvrJ PF12841.7 CCH58552.1 - 0.91 9.1 2.6 22 4.7 0.2 2.5 2 0 0 2 2 2 0 YvrJ protein family CLZ PF16526.5 CCH58552.1 - 2.2 8.7 8.4 24 5.4 0.2 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EMP24_GP25L PF01105.24 CCH58552.1 - 3.1 7.7 15.0 7.5 6.5 4.1 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD MerR-DNA-bind PF09278.11 CCH58552.1 - 5.2 7.7 7.2 17 6.0 3.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding Sec61_beta PF03911.16 CCH58553.1 - 2.3e-15 56.3 0.7 3.3e-15 55.8 0.7 1.2 1 0 0 1 1 1 1 Sec61beta family RRM_1 PF00076.22 CCH58554.1 - 5.8e-08 32.4 0.1 2e-07 30.7 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNISR PF15996.5 CCH58554.1 - 0.0026 18.1 18.7 0.0026 18.1 18.7 3.1 3 0 0 3 3 3 1 Arginine/serine-rich protein PNISR RRM_2 PF04059.12 CCH58554.1 - 0.03 14.5 0.1 0.072 13.3 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif 2 Tim54 PF11711.8 CCH58554.1 - 7.7 5.2 24.2 6.5 5.4 1.8 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Myb_DNA-binding PF00249.31 CCH58555.1 - 1.2e-09 38.2 1.5 6e-08 32.8 0.1 2.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH58555.1 - 2.1e-08 34.3 0.8 1e-07 32.1 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Mlf1IP PF10248.9 CCH58555.1 - 0.03 14.3 0.4 0.03 14.3 0.4 2.3 3 0 0 3 3 3 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Chorismate_bind PF00425.18 CCH58556.1 - 1.7e-88 296.6 0.0 2.7e-88 295.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CCH58556.1 - 1.1e-29 103.4 0.9 3e-27 95.6 0.2 3.3 2 2 0 2 2 2 2 Anthranilate synthase component I, N terminal region PTH2 PF01981.16 CCH58557.1 - 4e-44 149.6 0.1 7.2e-44 148.8 0.0 1.4 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 IF4E PF01652.18 CCH58558.1 - 5.3e-53 179.1 2.3 6.3e-53 178.8 2.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SBP_bac_1 PF01547.25 CCH58558.1 - 0.07 13.1 1.3 0.097 12.6 0.3 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Hydrolase_4 PF12146.8 CCH58559.1 - 1.8e-19 69.9 0.0 8.2e-12 44.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCH58559.1 - 1.1e-13 51.4 0.0 3.8e-09 36.6 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CCH58559.1 - 1.4e-05 24.7 0.0 4.6e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 CCH58559.1 - 3.1e-05 24.0 0.0 0.0022 18.0 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CCH58559.1 - 0.00023 21.1 0.1 0.016 15.0 0.1 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CCH58559.1 - 0.0013 19.3 0.0 0.0016 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.10 CCH58559.1 - 0.0016 17.6 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S28 PF05577.12 CCH58559.1 - 0.0023 16.8 0.0 0.0038 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 FSH1 PF03959.13 CCH58559.1 - 0.0023 17.6 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CCH58559.1 - 0.0024 17.4 0.0 0.021 14.4 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 CCH58559.1 - 0.007 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.12 CCH58559.1 - 0.024 14.6 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) LCD1 PF09798.9 CCH58559.1 - 0.043 12.3 0.0 0.058 11.9 0.0 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Sugar_tr PF00083.24 CCH58560.1 - 1.3e-114 383.6 33.6 1.5e-114 383.4 33.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58560.1 - 8.3e-25 87.5 38.1 1.5e-19 70.1 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mab-21 PF03281.14 CCH58561.1 - 0.28 10.4 2.5 5.2 6.3 2.6 2.4 1 1 0 1 1 1 0 Mab-21 protein zf-DNL PF05180.12 CCH58562.1 - 8.9e-30 102.4 2.3 1.7e-29 101.5 2.3 1.5 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 CCH58562.1 - 0.0025 17.7 0.7 0.085 12.8 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CCH58562.1 - 0.014 15.5 0.5 0.026 14.6 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 CCH58562.1 - 0.019 15.0 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0167 PF03691.14 CCH58562.1 - 0.031 14.1 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Elf1 PF05129.13 CCH58562.1 - 0.063 13.3 0.5 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 CCH58562.1 - 0.068 13.2 4.5 1 9.4 0.6 2.3 1 1 0 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 CCH58562.1 - 1.3 8.9 5.4 15 5.5 5.6 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) Glyco_hydro_72 PF03198.14 CCH58563.1 - 8.8e-134 445.7 0.6 1.2e-133 445.2 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CCH58563.1 - 0.0092 15.4 0.4 2 7.8 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) tRNA_anti-codon PF01336.25 CCH58564.1 - 6.5e-12 45.3 0.6 1.2e-11 44.4 0.6 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 CCH58564.1 - 1.7e-06 28.6 0.8 4.4e-06 27.3 0.1 2.2 2 1 0 2 2 2 1 Replication protein A C terminal CDC24_OB3 PF17244.2 CCH58564.1 - 0.019 14.7 0.6 0.03 14.0 0.1 1.5 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 CCH58564.1 - 0.031 14.5 0.1 0.065 13.4 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Rrf2 PF02082.20 CCH58564.1 - 0.073 13.4 0.1 0.53 10.7 0.0 2.4 3 0 0 3 3 3 0 Transcriptional regulator PCI PF01399.27 CCH58564.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 PCI domain HTH_24 PF13412.6 CCH58564.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Kri1_C PF12936.7 CCH58565.1 - 6.4e-30 103.2 3.7 6.4e-30 103.2 3.7 5.7 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 CCH58565.1 - 1.3e-11 45.0 16.1 1.3e-11 45.0 16.1 6.6 4 2 1 5 5 5 1 KRI1-like family Pkinase PF00069.25 CCH58566.1 - 1e-57 195.5 0.0 1.4e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58566.1 - 2.7e-29 102.2 0.0 3.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58566.1 - 7.1e-07 28.8 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCH58566.1 - 0.00047 19.6 0.1 0.00067 19.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH58566.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_S11 PF00411.19 CCH58567.1 - 0.0021 18.4 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L23eN PF03939.13 CCH58568.1 - 1.9e-19 69.6 10.2 1.9e-19 69.6 10.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CCH58568.1 - 2e-16 60.1 3.0 2e-16 60.1 3.0 2.7 2 2 0 2 2 2 1 Ribosomal protein L23 SSB PF00436.25 CCH58568.1 - 0.065 13.3 0.1 0.088 12.9 0.1 1.3 1 0 0 1 1 1 0 Single-strand binding protein family Ldh_1_N PF00056.23 CCH58569.1 - 5e-39 133.6 0.4 8.5e-39 132.9 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CCH58569.1 - 1.1e-31 110.0 0.1 4.4e-31 108.0 0.1 2.0 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Paramyxo_P_V_N PF13825.6 CCH58569.1 - 0.087 12.2 0.2 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus RRM_1 PF00076.22 CCH58570.1 - 8e-35 118.5 0.3 1.7e-16 59.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH58570.1 - 3.4e-13 49.5 0.4 1.4e-07 31.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CCH58570.1 - 0.04 13.6 0.2 10 5.9 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Ribosomal_S19e PF01090.19 CCH58571.1 - 6.4e-54 181.4 0.0 7.1e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18 PF17135.4 CCH58572.1 - 5.6e-87 290.0 4.3 6.2e-87 289.8 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CCH58572.1 - 0.00021 22.0 0.3 0.0006 20.5 0.3 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mrr_cat PF04471.12 CCH58572.1 - 0.17 12.0 0.3 0.69 9.9 0.1 2.0 2 1 1 3 3 3 0 Restriction endonuclease NTP_transf_2 PF01909.23 CCH58573.1 - 3.1e-19 69.1 0.0 3.1e-19 69.1 0.0 2.3 3 0 0 3 3 3 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CCH58573.1 - 3.9e-15 55.8 0.0 1.5e-14 53.9 0.0 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CCH58573.1 - 0.00018 21.5 0.0 0.00018 21.5 0.0 4.2 3 1 0 4 4 4 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 CCH58573.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm RF-1 PF00472.20 CCH58574.1 - 2.9e-19 69.1 1.2 3.6e-19 68.8 1.2 1.1 1 0 0 1 1 1 1 RF-1 domain DCB PF16213.5 CCH58575.1 - 9.4e-51 172.0 3.6 9.4e-51 172.0 3.6 4.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CCH58575.1 - 1e-29 103.5 6.8 1e-29 103.5 6.8 5.9 5 2 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CCH58575.1 - 1e-12 47.1 12.4 4.6e-10 38.3 0.1 3.5 3 0 0 3 3 3 2 C-terminal region of Mon2 protein Med15 PF09606.10 CCH58575.1 - 0.001 17.9 11.2 0.0016 17.2 11.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal EPL1 PF10513.9 CCH58575.1 - 0.0061 16.9 2.7 0.0061 16.9 2.7 3.0 3 0 0 3 3 2 1 Enhancer of polycomb-like RskA PF10099.9 CCH58575.1 - 0.036 14.4 2.3 0.059 13.7 2.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pex14_N PF04695.13 CCH58575.1 - 0.044 14.4 12.5 0.029 15.0 7.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3464 PF11947.8 CCH58575.1 - 0.079 12.7 1.3 0.21 11.3 1.3 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4834 PF16118.5 CCH58575.1 - 0.15 13.1 16.9 0.021 15.8 10.2 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) Suf PF05843.14 CCH58575.1 - 0.3 11.0 16.3 0.15 12.1 7.3 2.6 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Ctr PF04145.15 CCH58575.1 - 0.77 10.4 4.3 1.1 9.9 1.4 2.7 3 0 0 3 3 3 0 Ctr copper transporter family TFIIA PF03153.13 CCH58575.1 - 0.78 9.7 26.0 0.063 13.3 21.1 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MgsA_C PF12002.8 CCH58575.1 - 0.87 9.5 2.9 2.3 8.2 2.9 1.6 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF4407 PF14362.6 CCH58575.1 - 1.2 8.5 6.2 2.2 7.6 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF719 PF05334.13 CCH58575.1 - 2.3 8.4 11.3 0.17 12.1 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) TERB2 PF15101.6 CCH58575.1 - 3.7 7.5 12.2 11 6.0 12.2 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 CCH58575.1 - 3.9 7.0 38.4 0.052 13.2 25.5 3.3 3 0 0 3 3 3 0 Spt20 family RabGAP-TBC PF00566.18 CCH58576.1 - 6.9e-36 123.9 3.4 2.3e-27 96.0 0.2 4.5 3 1 0 4 4 4 2 Rab-GTPase-TBC domain Phage_tail_3 PF08813.11 CCH58576.1 - 0.17 11.5 4.9 0.052 13.2 0.6 2.1 2 0 0 2 2 2 0 Phage tail tube protein, TTP TruB_N PF01509.18 CCH58577.1 - 1.8e-39 135.5 0.1 8.5e-38 130.0 0.0 2.5 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CCH58577.1 - 2.8e-05 24.2 0.0 6.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain HMGL-like PF00682.19 CCH58577.1 - 0.13 11.8 0.0 0.64 9.5 0.0 2.0 1 1 0 1 1 1 0 HMGL-like UPF0154 PF03672.13 CCH58577.1 - 0.24 11.5 0.9 0.65 10.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Cyclin_N PF00134.23 CCH58578.1 - 4.9e-18 65.1 0.0 1.2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCH58578.1 - 2.2e-08 34.6 0.0 2.2e-08 34.6 0.0 2.3 2 1 0 2 2 2 1 Cyclin Rcd1 PF04078.13 CCH58579.1 - 3.8e-112 373.8 5.1 4.6e-112 373.5 5.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SRX PF09201.10 CCH58579.1 - 0.09 12.6 0.0 5 6.9 0.0 2.3 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit CorA PF01544.18 CCH58580.1 - 5e-43 147.5 4.5 1.7e-42 145.8 1.1 2.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2231 PF09990.9 CCH58580.1 - 0.085 13.3 0.5 0.15 12.5 0.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) PDT PF00800.18 CCH58581.1 - 2.5e-46 157.8 0.0 3.5e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 CCH58581.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 ACT domain AAA_23 PF13476.6 CCH58581.1 - 0.38 11.2 3.8 22 5.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain 6PF2K PF01591.18 CCH58582.1 - 2.9e-37 128.1 10.6 1.1e-36 126.2 10.6 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CCH58582.1 - 2.2e-05 24.6 0.2 6.1e-05 23.2 0.2 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCH58582.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_25 PF13481.6 CCH58582.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH58582.1 - 0.013 16.1 1.1 0.021 15.4 0.2 2.0 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CCH58582.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 CCH58582.1 - 0.078 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 CCH58582.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.9 3 1 1 4 4 4 0 AAA domain AAA PF00004.29 CCH58582.1 - 0.12 12.8 0.1 0.33 11.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH58582.1 - 0.2 12.0 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Hydrolase_4 PF12146.8 CCH58583.1 - 5.8e-17 61.8 0.0 3.9e-11 42.7 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCH58583.1 - 2.8e-09 37.0 0.1 1.3e-07 31.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CCH58583.1 - 1.1e-07 31.5 0.0 2.9e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 CCH58583.1 - 2.7e-05 24.0 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 CCH58583.1 - 0.00022 21.2 0.0 0.00086 19.3 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CCH58583.1 - 0.00031 20.6 0.0 0.0008 19.3 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CCH58583.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CCH58583.1 - 0.0022 17.6 0.0 0.012 15.2 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF818 PF05677.12 CCH58583.1 - 0.0024 16.9 0.6 0.0035 16.4 0.6 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Esterase PF00756.20 CCH58583.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 CCH58583.1 - 0.024 14.3 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S28 PF05577.12 CCH58583.1 - 0.03 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AXE1 PF05448.12 CCH58583.1 - 0.067 11.9 0.0 0.19 10.3 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 CCH58583.1 - 0.072 13.0 0.0 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) PAE PF03283.13 CCH58583.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase DUF2974 PF11187.8 CCH58583.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CCH58583.1 - 0.13 12.9 0.0 0.34 11.5 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Retrotrans_gag PF03732.17 CCH58584.1 - 4.6e-08 33.2 0.0 8.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CCH58584.1 - 8.5e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) ThiF PF00899.21 CCH58585.1 - 2.2e-66 223.7 0.0 2.8e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CCH58585.1 - 5.7e-09 36.3 0.2 2.9e-05 24.1 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CCH58585.1 - 0.0072 16.9 0.2 0.019 15.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF730 PF05325.11 CCH58585.1 - 0.032 14.3 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Polysacc_synt_2 PF02719.15 CCH58585.1 - 0.18 10.9 0.1 0.42 9.7 0.1 1.6 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein RhoGAP PF00620.27 CCH58586.1 - 2.5e-26 92.3 0.0 3.9e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Sugar_tr PF00083.24 CCH58587.1 - 2.4e-89 300.3 29.9 3e-89 300.0 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58587.1 - 1.2e-24 87.0 49.7 4.2e-24 85.1 29.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCH58587.1 - 0.21 9.9 9.5 0.023 13.1 1.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 CCH58587.1 - 0.39 11.3 2.4 0.41 11.2 0.6 2.0 2 0 0 2 2 2 0 Phage holin family 2 GTP_EFTU PF00009.27 CCH58588.1 - 3.5e-66 222.5 0.2 4.8e-66 222.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCH58588.1 - 1.3e-32 112.1 0.0 6.5e-32 109.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCH58588.1 - 1.6e-21 76.2 0.0 4.9e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CCH58588.1 - 1.3e-13 50.8 0.0 6.6e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CCH58588.1 - 2.6e-13 50.2 0.0 7.7e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH58588.1 - 0.00045 20.3 0.1 0.00095 19.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gpr1_Fun34_YaaH PF01184.19 CCH58589.1 - 1.7e-64 217.2 20.2 2.2e-64 216.9 20.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2207 PF09972.9 CCH58589.1 - 1.8 7.3 4.3 11 4.6 4.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YmaF PF12788.7 CCH58590.1 - 0.0087 16.6 0.0 0.13 12.8 0.0 2.1 2 0 0 2 2 2 1 YmaF family Spore_III_AB PF09548.10 CCH58590.1 - 0.018 15.1 2.1 0.05 13.7 0.3 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) IF-2B PF01008.17 CCH58590.1 - 0.23 10.6 2.0 0.36 10.0 1.0 1.7 1 1 1 2 2 2 0 Initiation factor 2 subunit family Iso_dh PF00180.20 CCH58591.1 - 1.1e-62 212.2 0.0 1.3e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ATP-synt_10 PF05176.14 CCH58592.1 - 6.6e-49 166.5 0.1 8.4e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 ATP10 protein SH2_2 PF14633.6 CCH58592.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 SH2 domain Arrestin_N PF00339.29 CCH58593.1 - 1.2e-05 25.4 0.0 6.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Peptidase_M16_M PF16187.5 CCH58595.1 - 1.9e-81 273.5 5.4 1.9e-81 273.5 5.4 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CCH58595.1 - 1.7e-33 115.7 0.5 1.1e-31 109.8 0.4 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCH58595.1 - 1.2e-30 106.9 3.0 9.6e-18 64.8 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Ovate PF04844.13 CCH58595.1 - 8.6 6.4 6.0 10 6.2 0.7 2.8 2 0 0 2 2 2 0 Transcriptional repressor, ovate RIBIOP_C PF04950.12 CCH58596.1 - 9.6e-103 343.6 0.0 1.7e-102 342.8 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCH58596.1 - 1.2e-22 79.8 0.0 2.8e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C2H2_2 PF12756.7 CCH58597.1 - 2.2e-31 108.2 8.4 1.5e-28 99.0 0.9 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Actin_micro PF17003.5 CCH58597.1 - 0.0021 17.3 14.4 0.41 9.8 4.2 3.1 2 1 0 3 3 3 3 Putative actin-like family zf-met PF12874.7 CCH58597.1 - 0.016 15.6 8.1 0.032 14.6 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCH58597.1 - 0.023 15.1 1.6 0.023 15.1 1.6 3.0 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH58597.1 - 0.023 15.5 0.6 0.023 15.5 0.6 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger CpXC PF14353.6 CCH58597.1 - 0.15 12.1 1.6 2.5 8.2 0.0 2.7 2 1 0 2 2 2 0 CpXC protein zf-C2HE PF16278.5 CCH58597.1 - 0.34 11.4 2.5 7.3 7.1 0.4 3.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 CCH58597.1 - 1.3 9.4 13.0 0.11 12.8 1.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Vac14_Fig4_bd PF11916.8 CCH58598.1 - 1.4e-68 230.0 6.7 3.3e-68 228.8 6.7 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CCH58598.1 - 3.9e-46 155.6 2.7 2.6e-38 130.5 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CCH58598.1 - 2.8e-08 33.3 0.9 0.00098 19.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CCH58598.1 - 5.3e-05 23.3 6.7 0.017 15.2 0.9 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CCH58598.1 - 0.00069 20.1 0.1 13 6.4 0.0 5.2 5 1 1 6 6 6 1 HEAT-like repeat RasGEF_N_2 PF14663.6 CCH58598.1 - 0.011 16.1 1.6 0.85 10.0 0.1 3.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ParcG PF10274.9 CCH58598.1 - 0.12 12.4 2.6 1.3 9.1 0.1 3.6 4 0 0 4 4 4 0 Parkin co-regulated protein Arm PF00514.23 CCH58598.1 - 0.3 11.2 8.7 4.8 7.4 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CCH58598.1 - 1.4 9.1 4.1 22 5.3 0.4 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 SWC7 PF17330.2 CCH58599.1 - 5.9e-32 109.6 3.9 1.9e-20 72.7 0.2 2.1 1 1 1 2 2 2 2 SWR1 chromatin-remodelling complex, sub-unit Swc7 Rad52_Rad22 PF04098.15 CCH58600.1 - 3.7e-11 43.2 0.1 5.6e-11 42.6 0.1 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Birna_VP2 PF01766.17 CCH58600.1 - 0.054 12.5 0.9 0.3 10.0 0.2 1.9 2 0 0 2 2 2 0 Birnavirus VP2 protein CRAL_TRIO PF00650.20 CCH58601.1 - 1.1e-40 139.0 0.0 1.7e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH58601.1 - 1e-08 35.2 0.1 2.6e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCH58601.1 - 5.5e-07 29.8 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ank_2 PF12796.7 CCH58602.1 - 4.5e-09 36.8 0.6 0.0047 17.5 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCH58602.1 - 2.6e-08 34.3 4.4 4.5e-05 23.9 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH58602.1 - 6.8e-06 26.0 0.7 0.15 12.7 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat KilA-N PF04383.13 CCH58602.1 - 1.5e-05 24.8 2.0 0.00039 20.2 0.3 2.9 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.30 CCH58602.1 - 0.00034 20.9 0.2 0.12 12.9 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CCH58602.1 - 0.0013 19.0 2.1 0.11 12.8 0.4 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Med9 PF07544.13 CCH58602.1 - 0.11 12.5 2.5 0.48 10.5 2.5 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 NTP_transferase PF00483.23 CCH58603.1 - 1.2e-54 185.5 0.0 1.6e-54 185.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CCH58603.1 - 4e-10 40.3 0.0 5.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CCH58603.1 - 5.3e-10 38.6 8.5 3.3e-07 29.8 2.8 3.2 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CCH58603.1 - 0.0012 18.6 5.3 0.15 11.9 1.9 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CCH58603.1 - 0.018 13.2 0.3 0.026 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CCH58603.1 - 0.048 12.6 0.0 0.22 10.4 0.0 1.9 2 1 1 3 3 3 0 L-fucokinase CTP_transf_3 PF02348.19 CCH58603.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Bactofilin PF04519.13 CCH58603.1 - 0.46 10.8 4.1 0.91 9.9 4.1 1.5 1 0 0 1 1 1 0 Polymer-forming cytoskeletal FBPase PF00316.20 CCH58604.1 - 7.2e-74 247.4 0.3 1.1e-73 246.8 0.3 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Acyltransferase PF01553.21 CCH58605.1 - 4.3e-31 107.3 0.0 6.9e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Glyco_trans_1_3 PF13528.6 CCH58605.1 - 0.0051 16.1 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 PSY3 PF16836.5 CCH58606.1 - 6e-72 241.7 2.1 6.8e-72 241.5 2.1 1.0 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description Spherulin4 PF12138.8 CCH58606.1 - 0.096 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 GHL15 PF14885.6 CCH58606.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 QRPTase_C PF01729.19 CCH58606.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.5 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain RT_RNaseH_2 PF17919.1 CCH58608.1 - 1.8e-20 72.8 0.0 3.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH58608.1 - 3e-18 66.0 0.0 6.7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCH58608.1 - 4.5e-18 65.1 0.2 1.1e-17 63.9 0.2 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CCH58608.1 - 4.3e-11 43.0 0.0 8.8e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain La PF05383.17 CCH58609.1 - 4.6e-17 61.8 0.1 9.2e-17 60.9 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CCH58609.1 - 0.00022 21.0 0.4 0.0028 17.4 0.4 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1834 PF08873.11 CCH58609.1 - 0.041 13.6 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) zf-C2H2_4 PF13894.6 CCH58610.1 - 0.00029 21.4 32.3 0.002 18.8 2.3 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCH58610.1 - 0.00044 20.2 1.6 0.00044 20.2 1.6 4.7 4 1 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH58610.1 - 0.002 18.5 3.9 0.002 18.5 3.9 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-SNAP50_C PF12251.8 CCH58610.1 - 0.0028 17.4 7.9 0.0041 16.8 1.7 2.4 2 1 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2_jaz PF12171.8 CCH58610.1 - 0.016 15.5 12.6 0.057 13.7 0.3 4.3 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding HRXXH PF13933.6 CCH58610.1 - 0.076 12.6 2.8 0.13 11.8 2.8 1.3 1 0 0 1 1 1 0 Putative peptidase family zf-met PF12874.7 CCH58610.1 - 2.9 8.4 12.3 0.54 10.7 1.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CCH58610.1 - 9.2 6.3 11.4 6.4 6.8 0.4 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Ribosomal_S8 PF00410.19 CCH58611.1 - 1.6e-23 83.0 0.1 2.1e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glutaredoxin PF00462.24 CCH58612.1 - 0.00013 22.2 0.2 0.00024 21.2 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CCH58612.1 - 0.068 13.2 0.9 0.064 13.2 0.9 1.3 1 1 0 1 1 1 0 Thioredoxin DUF2462 PF09495.10 CCH58613.1 - 3.1e-15 56.6 13.0 4e-15 56.3 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) GATase_5 PF13507.6 CCH58614.1 - 4.3e-98 327.6 0.1 6.4e-98 327.0 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CCH58614.1 - 1.1e-40 139.3 0.0 4.2e-30 105.0 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CCH58614.1 - 2.1e-25 88.9 0.0 4.1e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CCH58614.1 - 3.9e-22 78.5 0.1 1.5e-21 76.7 0.0 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain PIN_4 PF13638.6 CCH58615.1 - 0.00011 22.5 0.4 0.00024 21.4 0.2 1.7 1 1 0 1 1 1 1 PIN domain Anophelin PF10731.9 CCH58615.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Septin PF00735.18 CCH58616.1 - 3.4e-87 292.3 2.2 8.2e-87 291.1 2.2 1.7 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CCH58616.1 - 4.3e-07 30.0 5.7 8.9e-06 25.7 0.1 3.1 3 1 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CCH58616.1 - 4.7e-06 26.7 0.7 1.6e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH58616.1 - 6.6e-06 25.8 5.3 0.00043 19.9 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CCH58616.1 - 0.02 14.2 0.3 0.068 12.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2597 PF10772.9 CCH58616.1 - 0.059 13.4 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) Roc PF08477.13 CCH58616.1 - 0.064 13.5 1.8 0.097 12.9 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 CCH58616.1 - 0.074 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CCH58616.1 - 0.19 11.8 0.0 0.19 11.8 0.0 3.8 3 1 1 4 4 4 0 Dynamin family ABC_tran PF00005.27 CCH58616.1 - 0.33 11.5 4.1 0.33 11.5 0.2 2.7 2 1 0 2 2 2 0 ABC transporter EF-hand_7 PF13499.6 CCH58617.1 - 7.8e-07 29.5 4.0 0.00015 22.2 0.3 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CCH58617.1 - 1.5e-06 27.6 2.0 0.077 13.0 0.1 4.2 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 CCH58617.1 - 0.0026 17.2 0.9 21 4.9 0.0 4.4 5 0 0 5 5 5 1 EF hand Macoilin PF09726.9 CCH58617.1 - 1.1 7.8 10.8 1.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 CCH58617.1 - 7.4 5.3 10.4 10 4.8 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pkinase PF00069.25 CCH58618.1 - 2.1e-66 224.0 0.2 1.5e-64 217.9 0.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58618.1 - 5.5e-50 170.1 0.0 1.6e-49 168.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CCH58618.1 - 1.1e-34 118.8 0.2 3.7e-34 117.0 0.0 2.0 2 0 0 2 2 2 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CCH58618.1 - 3.6e-10 39.8 1.0 1.8e-09 37.6 1.0 2.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCH58618.1 - 4.3e-08 33.5 0.5 4.3e-08 33.5 0.5 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CCH58618.1 - 2.8e-05 23.6 0.0 0.00087 18.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCH58618.1 - 0.0029 16.5 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CCH58618.1 - 0.0069 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain SAM_4 PF18017.1 CCH58618.1 - 0.026 14.5 0.2 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) VPS38 PF17649.1 CCH58620.1 - 8.8e-157 522.3 27.1 9.9e-157 522.2 27.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Lyase_1 PF00206.20 CCH58621.1 - 3.1e-25 89.2 0.0 5.3e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CCH58621.1 - 2.9e-18 66.2 0.0 1.7e-17 63.7 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Bromodomain PF00439.25 CCH58622.1 - 3.2e-29 100.8 7.5 7.1e-17 61.3 0.4 2.9 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 CCH58622.1 - 6.2e-26 90.7 5.5 8e-26 90.3 0.8 3.0 3 0 0 3 3 3 1 BAH domain AA_permease_2 PF13520.6 CCH58623.1 - 1.5e-82 277.7 47.5 2e-82 277.3 47.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCH58623.1 - 8.6e-21 74.1 41.0 1.3e-20 73.5 41.0 1.2 1 0 0 1 1 1 1 Amino acid permease eIF2A PF08662.11 CCH58624.1 - 7.5e-74 247.8 0.1 4e-73 245.4 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CCH58624.1 - 5e-05 24.0 2.8 1.9 9.5 0.2 4.4 3 1 1 4 4 4 2 WD domain, G-beta repeat CAF1-p150_N PF15557.6 CCH58624.1 - 0.49 10.3 8.3 0.14 12.1 4.3 2.1 2 1 1 3 3 3 0 CAF1 complex subunit p150, region binding to PCNA SR-25 PF10500.9 CCH58624.1 - 9.8 5.7 24.5 16 5.0 23.9 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tti2 PF10521.9 CCH58626.1 - 4.5e-58 197.0 6.5 7.3e-58 196.3 6.5 1.3 1 0 0 1 1 1 1 Tti2 family Ipi1_N PF12333.8 CCH58626.1 - 0.084 13.5 0.8 0.23 12.1 0.3 2.2 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation IlvN PF07991.12 CCH58627.1 - 5.6e-45 152.9 0.0 8.7e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CCH58627.1 - 4.7e-41 140.4 0.1 9.9e-41 139.4 0.1 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 CCH58627.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2_4 PF13894.6 CCH58628.1 - 0.02 15.7 0.6 0.02 15.7 0.6 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH58628.1 - 0.054 14.0 16.8 0.49 10.9 1.3 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CCH58628.1 - 1.7 8.8 4.8 4.4 7.4 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TAL_FSA PF00923.19 CCH58629.1 - 4.5e-99 331.4 1.7 5.2e-99 331.2 1.7 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Prok-TraM PF09228.10 CCH58630.1 - 0.0086 16.4 1.1 0.033 14.5 0.1 2.6 2 0 0 2 2 2 1 Prokaryotic Transcriptional repressor TraM DUF3552 PF12072.8 CCH58630.1 - 0.023 14.1 5.0 0.031 13.7 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) LRR_4 PF12799.7 CCH58631.1 - 0.00021 21.6 13.1 0.0073 16.7 0.4 5.4 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCH58631.1 - 0.00053 19.8 5.4 17 5.8 0.1 5.8 6 0 0 6 6 6 2 Leucine Rich repeat Phage_pRha PF09669.10 CCH58631.1 - 0.022 15.3 0.3 0.47 11.0 0.1 3.2 3 1 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) F-box-like PF12937.7 CCH58631.1 - 0.079 12.9 0.4 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 F-box-like LRR_1 PF00560.33 CCH58631.1 - 0.31 11.8 13.9 1e+02 4.1 0.1 7.2 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 CCH58631.1 - 2.4 8.0 8.0 1.6 8.5 0.3 3.9 5 0 0 5 5 5 0 Leucine rich repeat Pkinase PF00069.25 CCH58632.1 - 1.5e-66 224.4 0.0 1.9e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58632.1 - 1.3e-31 109.8 0.0 1.8e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH58632.1 - 2.2e-05 23.6 0.2 3.1e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCH58632.1 - 0.00086 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCH58632.1 - 0.0054 16.1 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_VLTF3 PF04947.14 CCH58632.1 - 0.0097 15.7 5.3 0.012 15.3 4.1 1.7 2 0 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like APH PF01636.23 CCH58632.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCH58632.1 - 0.05 13.2 0.1 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Phage_sheath_1C PF17482.2 CCH58632.1 - 0.077 13.0 0.1 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 Phage tail sheath C-terminal domain CN_hydrolase PF00795.22 CCH58633.1 - 1.1e-59 202.0 0.0 1.2e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-C2H2 PF00096.26 CCH58635.1 - 5e-06 26.7 19.1 5e-05 23.5 2.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH58635.1 - 7e-06 26.2 5.9 2.6e-05 24.4 2.6 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCH58635.1 - 0.0011 19.1 1.1 0.0011 19.1 1.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCH58635.1 - 0.0023 18.6 1.1 0.0023 18.6 1.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 CCH58635.1 - 0.0034 18.0 11.7 0.2 12.3 1.4 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CCH58635.1 - 0.0035 17.6 3.7 0.013 15.7 3.7 2.0 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CCH58635.1 - 0.021 14.9 1.3 0.047 13.7 1.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 CCH58635.1 - 0.028 14.8 1.0 0.087 13.3 1.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CCH58635.1 - 0.059 13.8 5.2 0.21 12.0 5.2 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger CENP-B_dimeris PF09026.10 CCH58635.1 - 0.11 12.9 5.9 0.21 12.0 5.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zap1_zf2 PF18217.1 CCH58635.1 - 1 9.4 5.2 2.9 8.0 0.8 2.7 2 0 0 2 2 2 0 Zap1 zinc finger 2 CLP1_P PF16575.5 CCH58636.1 - 5.1e-32 111.2 0.2 3e-31 108.7 0.0 2.1 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CCH58636.1 - 0.0063 16.6 0.0 0.032 14.3 0.0 2.4 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 CCH58636.1 - 0.019 15.1 1.0 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 CCH58636.1 - 0.024 14.7 0.0 0.077 13.1 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase GIY-YIG PF01541.24 CCH58636.1 - 0.026 14.8 0.3 6.4 7.1 0.1 3.6 2 1 0 2 2 2 0 GIY-YIG catalytic domain AAA_29 PF13555.6 CCH58636.1 - 0.11 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 CCH58636.1 - 0.12 12.9 0.0 0.34 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain YqfQ PF14181.6 CCH58636.1 - 2.1 8.5 3.8 1.4 9.0 0.0 2.4 3 0 0 3 3 3 0 YqfQ-like protein KH_1 PF00013.29 CCH58638.1 - 2.1e-10 40.2 0.0 0.01 15.6 0.0 5.1 6 0 0 6 6 6 2 KH domain Phosphodiest PF01663.22 CCH58639.1 - 1.7e-10 41.1 0.4 2.7e-10 40.4 0.4 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCH58639.1 - 0.024 14.0 0.2 0.042 13.2 0.2 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.23 CCH58639.1 - 0.039 13.4 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 Sulfatase Cellulase PF00150.18 CCH58639.1 - 0.077 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 CCH58640.1 - 9e-39 133.4 29.4 9e-39 133.4 29.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58640.1 - 3.1e-06 26.3 36.7 0.00011 21.3 28.5 3.6 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CCH58641.1 - 6.7e-31 107.5 25.2 6.7e-31 107.5 25.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CCH58642.1 - 1.6e-41 142.4 29.6 1.6e-41 142.4 29.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58642.1 - 7.9e-13 48.1 4.8 7.9e-13 48.1 4.8 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CCH58642.1 - 0.00015 20.3 4.4 0.0003 19.3 4.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CCH58643.1 - 4.5e-42 144.2 32.3 4.5e-42 144.2 32.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58643.1 - 4.6e-12 45.6 7.8 4.6e-12 45.6 7.8 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter AAA_2 PF07724.14 CCH58644.1 - 5.6e-46 156.8 0.1 6.9e-45 153.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCH58644.1 - 4.5e-28 97.2 5.8 7.6e-28 96.5 3.3 2.8 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CCH58644.1 - 1.2e-23 83.0 0.3 5.7e-23 80.8 0.3 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CCH58644.1 - 5.2e-21 75.4 4.7 1.7e-13 51.2 0.1 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 CCH58644.1 - 1.7e-15 56.8 4.6 2.5e-09 37.1 0.8 3.4 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CCH58644.1 - 1.4e-14 54.3 0.0 2e-07 31.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CCH58644.1 - 2.3e-12 46.9 0.2 4.4e-08 33.0 0.0 3.1 2 2 1 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 CCH58644.1 - 1.1e-08 35.6 2.9 9e-05 22.9 0.0 4.2 4 1 0 4 4 3 2 AAA ATPase domain TniB PF05621.11 CCH58644.1 - 5e-06 26.1 0.2 0.0015 18.0 0.1 3.8 2 1 1 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 CCH58644.1 - 1.2e-05 25.6 0.4 0.16 12.2 0.1 4.1 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCH58644.1 - 1.4e-05 24.5 1.2 0.22 10.7 0.0 3.4 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_7 PF12775.7 CCH58644.1 - 5.1e-05 22.9 0.0 0.045 13.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 CCH58644.1 - 0.00016 21.2 0.0 0.37 10.1 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCH58644.1 - 0.00027 20.7 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Torsin PF06309.11 CCH58644.1 - 0.0011 19.1 0.0 0.0056 16.8 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA_3 PF07726.11 CCH58644.1 - 0.0016 18.3 0.0 0.42 10.5 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CCH58644.1 - 0.0024 17.8 0.2 1 9.3 0.0 3.1 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.12 CCH58644.1 - 0.0035 16.7 0.1 0.45 9.7 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 CCH58644.1 - 0.009 16.2 0.1 1.2 9.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CCH58644.1 - 0.012 15.4 0.0 0.47 10.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 CCH58644.1 - 0.025 14.6 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CCH58644.1 - 0.028 14.8 0.9 1.3 9.3 0.3 3.5 2 2 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCH58644.1 - 0.035 14.0 7.1 3.6 7.4 0.1 4.3 3 2 1 4 4 4 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CCH58644.1 - 0.061 13.1 0.0 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PEPCK_ATP PF01293.20 CCH58644.1 - 0.068 11.8 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase ABC_tran PF00005.27 CCH58644.1 - 0.079 13.5 2.1 6.2 7.3 0.0 3.7 4 0 0 4 4 4 0 ABC transporter RNA_helicase PF00910.22 CCH58644.1 - 0.087 13.2 0.1 19 5.7 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Roc PF08477.13 CCH58644.1 - 0.092 13.0 0.0 13 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase VTC PF09359.10 CCH58644.1 - 0.33 10.3 6.0 0.076 12.4 2.7 1.6 2 0 0 2 2 1 0 VTC domain Spc7 PF08317.11 CCH58644.1 - 0.94 8.3 15.7 1.7 7.4 15.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein RRM_1 PF00076.22 CCH58645.1 - 1e-30 105.4 3.0 9.7e-15 54.2 0.4 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 CCH58645.1 - 3.5e-05 23.7 0.0 0.069 13.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_occluded PF16842.5 CCH58645.1 - 0.0007 19.4 0.0 0.92 9.4 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM PF05172.13 CCH58645.1 - 0.0021 18.0 0.7 0.25 11.3 0.0 3.0 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CCH58645.1 - 0.0082 16.1 0.2 0.6 10.1 0.0 2.8 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 CCH58645.1 - 0.028 14.3 0.2 0.093 12.7 0.1 1.9 2 0 0 2 2 2 0 RL domain PHM7_cyt PF14703.6 CCH58645.1 - 0.031 14.5 0.1 1.6 8.9 0.1 2.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CCH58645.1 - 0.086 13.0 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif EMC3_TMCO1 PF01956.16 CCH58646.1 - 3.6e-58 196.0 1.1 4.5e-58 195.7 1.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ATP_bind_1 PF03029.17 CCH58647.1 - 1.8e-79 266.9 0.1 1.8e-79 266.9 0.1 1.4 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CCH58647.1 - 2.6e-07 30.4 0.1 2.9e-06 27.0 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CCH58647.1 - 1.9e-05 24.5 0.3 5.3e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCH58647.1 - 9.8e-05 22.4 0.2 0.0045 17.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCH58647.1 - 0.00038 20.1 0.1 0.042 13.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 CCH58647.1 - 0.0004 20.3 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 CCH58647.1 - 0.00058 19.7 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 CCH58647.1 - 0.00074 19.5 0.0 3 7.7 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase MeaB PF03308.16 CCH58647.1 - 0.00077 18.5 0.0 0.54 9.2 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CCH58647.1 - 0.0011 18.5 0.1 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CCH58647.1 - 0.0015 18.3 0.1 0.027 14.2 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CCH58647.1 - 0.0016 18.1 0.2 0.017 14.7 0.2 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.6 CCH58647.1 - 0.0024 17.8 0.1 0.092 12.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 CCH58647.1 - 0.0026 18.0 0.3 0.2 11.9 0.0 2.8 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CCH58647.1 - 0.0026 17.9 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH58647.1 - 0.0055 17.2 0.3 0.043 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain YuiB PF14068.6 CCH58647.1 - 0.0078 16.8 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative membrane protein AAA_30 PF13604.6 CCH58647.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 CCH58647.1 - 0.015 15.7 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CCH58647.1 - 0.017 15.4 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCH58647.1 - 0.019 14.9 0.1 0.18 11.7 0.1 2.2 1 1 0 1 1 1 0 NTPase NB-ARC PF00931.22 CCH58647.1 - 0.019 14.1 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 CCH58647.1 - 0.021 15.2 0.6 0.33 11.4 0.0 2.8 3 0 0 3 3 3 0 RNA helicase PRK PF00485.18 CCH58647.1 - 0.03 14.1 0.2 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 CCH58647.1 - 0.035 13.6 0.0 4 6.9 0.0 2.7 3 0 0 3 3 2 0 ADP-ribosylation factor family DUF87 PF01935.17 CCH58647.1 - 0.046 13.8 2.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 CCH58647.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CCH58647.1 - 0.32 10.4 5.8 0.36 10.3 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PAC2 PF09754.9 CCH58648.1 - 1.1e-15 58.2 0.0 1.2e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 PAC2 family MGDG_synth PF06925.11 CCH58648.1 - 0.3 11.2 2.2 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase LSM PF01423.22 CCH58649.1 - 1.7e-19 69.2 0.3 2.1e-19 69.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain Metallophos PF00149.28 CCH58651.1 - 1.6e-35 123.5 0.1 2e-35 123.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCH58651.1 - 0.1 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ham1p_like PF01725.16 CCH58653.1 - 2.5e-49 167.7 0.0 2.8e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF5365 PF17326.2 CCH58654.1 - 0.035 14.5 0.4 0.045 14.2 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5365) KIAA1430 PF13879.6 CCH58654.1 - 0.077 13.8 4.0 0.088 13.6 4.0 1.1 1 0 0 1 1 1 0 KIAA1430 homologue CENP-H PF05837.12 CCH58654.1 - 0.15 12.5 1.8 0.17 12.3 1.8 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Y_phosphatase2 PF03162.13 CCH58655.1 - 2e-43 147.8 6.3 9.6e-42 142.4 6.3 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family GARS_N PF02844.15 CCH58655.1 - 0.13 13.1 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Y_phosphatase3 PF13350.6 CCH58655.1 - 0.15 12.0 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Asp_protease PF09668.10 CCH58656.1 - 2.3e-51 172.8 0.2 3.9e-51 172.0 0.2 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCH58656.1 - 2.1e-18 66.6 1.7 8.2e-18 64.8 0.1 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCH58656.1 - 1.4e-07 32.0 1.6 2e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 CCH58656.1 - 6.2e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 CCH58656.1 - 0.0084 16.4 0.1 0.034 14.5 0.1 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 CCH58656.1 - 0.012 16.1 0.1 0.029 14.9 0.1 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pex14_N PF04695.13 CCH58656.1 - 0.059 14.0 4.4 0.12 13.0 4.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glutaredoxin2_C PF04399.13 CCH58656.1 - 0.13 12.1 0.5 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain COX15-CtaA PF02628.15 CCH58657.1 - 9.3e-117 389.7 4.9 1.1e-116 389.4 4.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Pentapeptide_4 PF13599.6 CCH58657.1 - 0.033 14.4 0.2 0.07 13.3 0.2 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 CCH58657.1 - 0.26 11.5 1.3 0.56 10.4 1.3 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) DUF2339 PF10101.9 CCH58657.1 - 0.62 8.6 11.8 5.8 5.4 11.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) NADH-u_ox-rdase PF10785.9 CCH58657.1 - 0.9 10.3 4.3 2.5 8.9 0.1 3.3 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF747 PF05346.11 CCH58658.1 - 1.7e-80 270.9 17.3 3.3e-80 269.9 17.3 1.4 1 1 0 1 1 1 1 Eukaryotic membrane protein family Ribosomal_S13_N PF08069.12 CCH58659.1 - 2.9e-25 88.1 0.1 5.4e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CCH58659.1 - 1e-14 54.4 0.1 1.6e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 Aminotran_1_2 PF00155.21 CCH58660.1 - 1.9e-69 234.6 0.0 2.3e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCH58660.1 - 0.00036 19.6 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 CCH58660.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain ABC_tran PF00005.27 CCH58661.1 - 6.8e-30 104.4 1.7 5.9e-18 65.7 0.1 3.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CCH58661.1 - 3e-10 40.4 6.3 1.3e-06 28.5 0.0 3.9 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH58661.1 - 0.00075 19.2 0.1 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CCH58661.1 - 0.0015 18.8 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 CCH58661.1 - 0.0017 18.5 0.0 0.69 10.2 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CCH58661.1 - 0.0051 17.1 2.0 4 7.7 0.1 3.8 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCH58661.1 - 0.0085 16.6 0.1 3.1 8.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF4241 PF14025.6 CCH58661.1 - 0.011 16.0 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) AAA PF00004.29 CCH58661.1 - 0.018 15.4 0.6 22 5.5 0.0 4.2 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCH58661.1 - 0.023 14.4 0.1 2.9 7.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain SMC_N PF02463.19 CCH58661.1 - 0.027 13.9 0.1 13 5.2 0.0 3.1 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain Ploopntkinase1 PF18748.1 CCH58661.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 MEIOC PF15189.6 CCH58661.1 - 0.1 12.2 1.4 1.2 8.7 0.1 2.5 3 0 0 3 3 3 0 Meiosis-specific coiled-coil domain-containing protein MEIOC UAF_Rrn10 PF05234.11 CCH58662.1 - 9.7e-32 109.7 0.1 1.2e-31 109.4 0.1 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Methyltr_RsmB-F PF01189.17 CCH58663.1 - 4.1e-41 140.8 0.0 2e-40 138.6 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCH58663.1 - 0.0039 17.3 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Nitr_red_alph_N PF14710.6 CCH58663.1 - 0.2 12.2 0.7 0.52 10.8 0.7 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal PHD PF00628.29 CCH58664.1 - 1.2 9.1 20.8 0.17 11.8 1.3 3.9 3 1 0 3 3 3 0 PHD-finger Lon_C PF05362.13 CCH58665.1 - 8.2e-66 221.5 0.0 4.6e-65 219.0 0.0 2.2 3 0 0 3 3 3 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CCH58665.1 - 1.8e-33 116.2 8.2 1.8e-33 116.2 8.2 2.9 3 1 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CCH58665.1 - 2.4e-23 83.0 0.1 7.5e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCH58665.1 - 6e-05 23.1 0.0 0.00019 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCH58665.1 - 9.3e-05 22.8 0.2 0.3 11.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase ChlI PF13541.6 CCH58665.1 - 0.00012 21.9 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 CCH58665.1 - 0.00023 21.5 0.1 0.0023 18.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 CCH58665.1 - 0.00042 19.3 0.0 0.00087 18.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 CCH58665.1 - 0.0021 17.8 0.0 0.017 14.9 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CCH58665.1 - 0.0047 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CCH58665.1 - 0.0057 17.0 1.1 0.018 15.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CCH58665.1 - 0.0077 16.3 0.0 0.047 13.7 0.0 2.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 CCH58665.1 - 0.061 13.5 1.5 0.26 11.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.6 CCH58665.1 - 0.12 13.0 0.0 0.12 13.0 0.0 4.1 5 0 0 5 5 5 0 AAA domain Zip PF02535.22 CCH58665.1 - 1 8.5 7.3 0.41 9.8 2.1 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Rft-1 PF04506.13 CCH58666.1 - 5.1e-219 728.2 42.6 5.8e-219 728.1 42.6 1.0 1 0 0 1 1 1 1 Rft protein Phlebovirus_G2 PF07245.11 CCH58666.1 - 0.04 12.4 0.4 0.067 11.7 0.4 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Exo_endo_phos PF03372.23 CCH58667.1 - 9.8e-17 61.2 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CCH58667.1 - 1.2e-11 44.5 1.4 2.4e-11 43.6 1.4 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CCH58667.1 - 1.5e-07 31.3 0.5 0.075 12.9 0.0 3.5 2 1 1 3 3 3 3 Endonuclease-reverse transcriptase AvrPphF-ORF-2 PF09143.10 CCH58668.1 - 0.021 14.8 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 AvrPphF-ORF-2 Sortilin-Vps10 PF15902.5 CCH58669.1 - 2.5e-204 679.1 21.0 2.3e-140 468.4 3.3 3.3 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CCH58669.1 - 2.7e-64 216.6 19.0 5.7e-38 130.9 1.4 2.8 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CCH58669.1 - 4.2e-17 59.3 41.3 0.47 10.6 0.0 13.2 13 0 0 13 13 13 9 BNR/Asp-box repeat CHB_HEX_C PF03174.13 CCH58669.1 - 0.00052 19.9 3.4 1.6 8.7 0.0 4.5 4 1 1 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Mo-co_dimer PF03404.16 CCH58669.1 - 0.0011 18.9 0.1 21 5.1 0.0 4.9 5 0 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain BNR_6 PF15899.5 CCH58669.1 - 2 8.7 11.2 3.7 7.9 0.1 5.3 6 0 0 6 6 6 0 BNR-Asp box repeat Pkinase PF00069.25 CCH58670.1 - 1.4e-66 224.6 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58670.1 - 2.7e-31 108.8 0.0 3.5e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58670.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCH58670.1 - 0.00085 18.4 1.5 0.0027 16.7 1.5 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCH58670.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH58670.1 - 0.2 11.5 0.1 0.44 10.4 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Acid_PPase PF12689.7 CCH58671.1 - 2.1e-42 144.8 0.0 2.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase EMP24_GP25L PF01105.24 CCH58672.1 - 8.7e-44 149.6 0.0 1e-43 149.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Metallophos PF00149.28 CCH58673.1 - 2.7e-40 139.1 0.1 3.5e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCH58673.1 - 1.1e-22 80.2 1.5 1.8e-22 79.5 0.5 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain TIM21 PF08294.11 CCH58674.1 - 8.1e-37 126.3 0.0 1.1e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Glyco_hydro_72 PF03198.14 CCH58675.1 - 4.7e-139 463.0 1.6 8.2e-139 462.2 1.6 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CCH58675.1 - 2.5e-16 60.1 0.2 5.1e-16 59.1 0.2 1.6 1 0 0 1 1 1 1 X8 domain FYDLN_acid PF09538.10 CCH58675.1 - 5.9 7.6 9.0 18 6.1 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Glucan_synthase PF02364.15 CCH58676.1 - 0 1346.6 0.0 0 1346.0 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCH58676.1 - 4.4e-41 140.2 0.5 2.1e-40 138.1 0.2 2.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3817 PF12823.7 CCH58676.1 - 0.36 11.7 9.2 0.081 13.8 2.3 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Abhydrolase_1 PF00561.20 CCH58677.1 - 8.5e-16 58.4 0.0 1e-14 54.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCH58677.1 - 2.7e-15 57.6 0.0 3.2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCH58677.1 - 1.9e-11 43.7 0.0 3.6e-11 42.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CCH58677.1 - 5.3e-07 30.0 0.0 8e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CCH58677.1 - 5e-05 23.1 0.1 0.0026 17.5 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CCH58677.1 - 6e-05 22.7 0.0 9.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.20 CCH58677.1 - 0.00038 20.2 0.0 0.00096 18.9 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 CCH58677.1 - 0.00044 20.2 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CCH58677.1 - 0.0078 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.16 CCH58677.1 - 0.0092 15.8 0.1 0.042 13.7 0.0 2.0 1 1 2 3 3 3 1 Phospholipase/Carboxylesterase Abhydro_lipase PF04083.16 CCH58677.1 - 0.088 12.4 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_3 PF07859.13 CCH58677.1 - 0.17 11.7 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold NUC153 PF08159.12 CCH58678.1 - 1.1e-10 41.1 3.9 2.4e-10 40.1 3.9 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CCH58678.1 - 0.012 16.5 0.7 54 4.9 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58678.1 - 0.018 15.3 0.0 0.19 12.1 0.0 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain V-SNARE_C PF12352.8 CCH58679.1 - 0.032 14.5 6.1 0.17 12.2 0.5 2.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Phage_connect_1 PF05135.13 CCH58679.1 - 0.22 12.1 7.1 0.14 12.7 2.9 2.8 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein PIEZO PF15917.5 CCH58679.1 - 0.32 10.4 23.8 0.017 14.6 5.5 3.4 3 0 0 3 3 3 0 Piezo zf-H2C2_2 PF13465.6 CCH58680.1 - 8.7e-10 38.6 15.2 3e-05 24.2 4.0 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CCH58680.1 - 6.5e-08 32.6 15.7 0.00061 20.1 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH58680.1 - 0.0014 19.3 13.0 0.29 12.1 4.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCH58680.1 - 0.019 15.0 1.4 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CCH58680.1 - 0.56 10.9 0.1 0.56 10.9 0.1 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCH58680.1 - 0.76 10.1 2.6 0.81 10.0 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 CCH58680.1 - 2 8.3 3.9 8.6 6.3 0.3 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_8 PF15909.5 CCH58680.1 - 2.3 8.6 8.4 0.21 11.9 0.5 2.7 2 1 1 3 3 3 0 C2H2-type zinc ribbon DUF1279 PF06916.13 CCH58681.1 - 2.5e-20 72.8 0.0 3.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) PaaA_PaaC PF05138.12 CCH58681.1 - 0.065 12.4 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein Ribosomal_L24e PF01246.20 CCH58682.1 - 1.5e-30 105.2 0.2 1.5e-30 105.2 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CCH58682.1 - 0.039 13.5 2.6 0.052 13.1 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DDHD PF02862.17 CCH58682.1 - 1.3 9.1 6.7 1.7 8.8 6.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF936 PF06075.12 CCH58683.1 - 0.28 10.1 48.2 0.37 9.7 48.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Glyco_hydro_63 PF03200.16 CCH58684.1 - 1e-173 578.6 8.8 6.3e-173 576.0 8.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CCH58684.1 - 2.9e-61 207.5 0.0 7.4e-61 206.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CCH58684.1 - 0.00013 21.0 0.2 0.00022 20.3 0.2 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_36 PF17167.4 CCH58684.1 - 0.0054 15.5 0.3 0.019 13.7 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain FlaE PF07559.14 CCH58684.1 - 0.22 12.1 2.6 0.64 10.6 0.0 2.8 3 1 0 3 3 3 0 Flagellar basal body protein FlaE Rrn6 PF10214.9 CCH58685.1 - 4.5e-140 468.8 23.7 5.8e-140 468.4 23.7 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.20 CCH58686.1 - 8.1e-99 329.7 0.4 1.2e-98 329.1 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CCH58686.1 - 4.8e-47 160.8 2.6 1e-46 159.7 1.0 2.2 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme HMGL-like PF00682.19 CCH58686.1 - 0.067 12.7 0.2 41 3.6 0.0 3.3 3 0 0 3 3 3 0 HMGL-like Med3 PF11593.8 CCH58687.1 - 8.2e-16 58.2 9.0 8.2e-16 58.2 9.0 4.4 1 1 2 3 3 3 1 Mediator complex subunit 3 fungal CENP-F_leu_zip PF10473.9 CCH58687.1 - 0.19 11.8 1.9 15 5.6 0.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 CCH58687.1 - 0.3 11.2 5.7 0.13 12.4 1.1 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation FYVE PF01363.21 CCH58688.1 - 6.8e-14 51.8 9.4 1.4e-13 50.7 9.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger STT3 PF02516.14 CCH58689.1 - 5e-145 484.1 52.0 4.6e-143 477.7 47.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 CCH58689.1 - 0.0024 18.1 12.2 0.0024 18.1 12.2 4.0 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Hyccin PF09790.9 CCH58689.1 - 0.14 11.2 1.3 0.23 10.5 1.3 1.2 1 0 0 1 1 1 0 Hyccin HSCB_C PF07743.13 CCH58690.1 - 3.2e-16 59.6 3.0 3.2e-16 59.6 3.0 2.2 2 1 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CCH58690.1 - 1.7e-07 31.2 1.0 5.8e-07 29.6 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Pan3_PK PF18101.1 CCH58690.1 - 0.026 14.5 0.7 0.043 13.8 0.7 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain UVR PF02151.19 CCH58690.1 - 0.03 14.1 1.4 0.054 13.3 0.1 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif Tmpp129 PF10272.9 CCH58690.1 - 0.036 13.4 0.2 0.04 13.2 0.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Aconitase PF00330.20 CCH58691.1 - 2.5e-159 531.2 0.1 3.1e-159 530.9 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCH58691.1 - 4.3e-43 146.8 0.0 8.4e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.18 CCH58692.1 - 1.7e-22 79.7 6.1 1.7e-22 79.7 6.1 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH58692.1 - 2e-05 24.6 5.8 3.6e-05 23.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.20 CCH58693.1 - 3.3e-45 153.8 4.7 8.7e-45 152.5 4.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH58693.1 - 2.1e-20 73.9 1.7 7.1e-20 72.2 0.1 2.7 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCH58693.1 - 5.4e-11 42.0 0.2 1.5e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCH58693.1 - 0.0022 17.8 0.1 0.005 16.6 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH58693.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) O-antigen_lig PF13425.6 CCH58693.1 - 0.15 10.8 7.8 0.12 11.2 6.1 1.6 2 0 0 2 2 2 0 O-antigen ligase like membrane protein TMPIT PF07851.13 CCH58694.1 - 0.00044 19.6 4.7 0.00059 19.2 4.7 1.1 1 0 0 1 1 1 1 TMPIT-like protein Herpes_BBRF1 PF04793.12 CCH58694.1 - 0.11 11.5 0.7 0.2 10.7 0.7 1.5 1 1 0 1 1 1 0 BRRF1-like protein CorA PF01544.18 CCH58694.1 - 0.39 10.0 5.5 0.73 9.1 5.4 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein WD40 PF00400.32 CCH58695.1 - 9.5e-12 45.3 1.1 1.8e-06 28.6 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat NBD94 PF16830.5 CCH58695.1 - 8.6 6.8 15.6 0.046 14.1 4.7 2.7 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH FAD-oxidase_C PF02913.19 CCH58696.1 - 1.2e-56 192.2 0.1 1.6e-56 191.7 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCH58696.1 - 3.2e-35 120.9 0.0 6.4e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain RRM_1 PF00076.22 CCH58696.1 - 0.039 13.8 0.1 13 5.6 0.0 3.8 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 CCH58697.1 - 1.4e-15 57.6 26.2 3.9e-10 40.2 0.5 5.0 3 2 2 5 5 5 4 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 CCH58697.1 - 0.45 10.1 3.9 2.6 7.6 0.1 3.3 3 0 0 3 3 3 0 GTP1/OBG GATase_2 PF00310.21 CCH58698.1 - 2.2e-166 553.7 0.0 3.7e-166 553.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CCH58698.1 - 3e-154 513.6 0.0 1.9e-153 511.0 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CCH58698.1 - 9.7e-110 366.4 0.0 1.3e-107 359.5 0.0 2.6 2 1 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CCH58698.1 - 2.5e-70 236.0 1.2 4.5e-70 235.1 1.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 CCH58698.1 - 7e-23 80.6 0.0 1.3e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 CCH58698.1 - 2.8e-20 72.7 0.0 1.2e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCH58698.1 - 1.2e-08 35.0 0.0 3.5e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCH58698.1 - 5.9e-06 26.7 0.2 0.00092 19.7 0.1 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CCH58698.1 - 6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 CCH58698.1 - 2.9e-05 23.5 0.1 0.0052 16.1 0.0 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCH58698.1 - 0.00022 20.1 0.3 0.00054 18.8 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 CCH58698.1 - 0.00045 20.2 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.7 CCH58698.1 - 0.0011 18.5 0.4 0.002 17.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CCH58698.1 - 0.0015 17.9 0.0 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 CCH58698.1 - 0.0042 16.4 0.3 0.014 14.6 0.1 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CCH58698.1 - 0.0064 16.1 0.2 0.017 14.7 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCH58698.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GATase_6 PF13522.6 CCH58698.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_7 PF13241.6 CCH58698.1 - 0.033 14.6 0.0 18 5.8 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CCH58698.1 - 0.04 13.2 0.0 0.08 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 CCH58698.1 - 0.046 12.1 0.5 13 4.0 0.0 3.2 3 1 0 3 3 3 0 Flavin-binding monooxygenase-like F420_oxidored PF03807.17 CCH58698.1 - 0.052 14.1 1.7 0.13 12.8 0.0 2.6 3 0 0 3 3 1 0 NADP oxidoreductase coenzyme F420-dependent FMN_dh PF01070.18 CCH58698.1 - 0.084 11.9 0.5 0.37 9.8 0.8 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_2 PF03446.15 CCH58698.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CCH58698.1 - 0.22 11.1 1.3 0.59 9.7 0.1 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 CCH58698.1 - 0.73 9.7 2.2 0.47 10.3 0.0 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRELI PF04707.14 CCH58699.1 - 1.3e-44 151.8 1.4 1.6e-44 151.5 1.4 1.0 1 0 0 1 1 1 1 PRELI-like family PTR2 PF00854.21 CCH58700.1 - 1e-97 327.5 10.1 5.1e-97 325.2 10.1 1.8 1 1 0 1 1 1 1 POT family DUF1129 PF06570.11 CCH58700.1 - 0.25 10.8 7.5 0.57 9.6 2.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SRP40_C PF05022.12 CCH58701.1 - 1.8e-22 79.9 2.6 1.8e-22 79.9 2.6 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain Whi5 PF08528.11 CCH58702.1 - 1e-10 41.0 0.1 2.1e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Whi5 like IBN_N PF03810.19 CCH58702.1 - 0.02 14.8 0.1 0.066 13.1 0.1 1.9 1 0 0 1 1 1 0 Importin-beta N-terminal domain LIM PF00412.22 CCH58703.1 - 6.4e-16 58.3 23.5 2.1e-09 37.4 8.4 2.5 2 0 0 2 2 2 2 LIM domain DUF3336 PF11815.8 CCH58704.1 - 2e-34 118.3 9.6 4.4e-34 117.2 9.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCH58704.1 - 5.5e-26 92.0 0.0 5e-25 88.9 0.0 2.4 3 0 0 3 3 3 1 Patatin-like phospholipase F-box-like PF12937.7 CCH58705.1 - 1.9e-08 34.0 0.1 4.3e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCH58705.1 - 2.7e-06 27.1 0.2 7.5e-06 25.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 CCH58705.1 - 4e-05 23.4 1.5 0.0016 18.4 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH58705.1 - 0.00087 19.2 0.0 0.22 11.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCH58705.1 - 0.0024 17.6 0.0 0.05 13.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCH58705.1 - 0.011 16.0 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCH58705.1 - 0.055 14.1 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Tfb4 PF03850.14 CCH58705.1 - 0.084 12.4 0.7 0.16 11.4 0.7 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 LRR_1 PF00560.33 CCH58705.1 - 0.15 12.7 4.9 1.3e+02 3.8 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 CCH58705.1 - 0.15 12.2 1.3 0.55 10.4 0.1 2.8 3 0 0 3 3 1 0 Leucine Rich repeat p12I PF12233.8 CCH58705.1 - 0.2 12.2 3.5 0.11 13.0 0.6 2.0 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein LRR_4 PF12799.7 CCH58705.1 - 3.1 8.4 15.5 14 6.3 0.0 6.1 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Zip PF02535.22 CCH58706.1 - 2.2e-41 142.2 14.0 1.2e-23 83.9 6.8 2.6 2 1 0 2 2 2 2 ZIP Zinc transporter Jagunal PF07086.12 CCH58706.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.6 3 0 0 3 3 3 0 Jagunal, ER re-organisation during oogenesis U3_snoRNA_assoc PF08297.11 CCH58707.1 - 2.6e-20 72.9 5.4 2.6e-20 72.9 5.4 3.1 2 1 0 2 2 2 1 U3 snoRNA associated BSP_II PF05432.11 CCH58707.1 - 3.2 7.4 16.7 4 7.1 16.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SNARE_assoc PF09335.11 CCH58708.1 - 1.2e-14 54.9 5.3 1.2e-14 54.9 5.3 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein VIT1 PF01988.19 CCH58708.1 - 0.098 12.5 0.5 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 VIT family TctB PF07331.11 CCH58708.1 - 0.11 12.8 11.2 0.08 13.2 7.2 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ParD PF09386.10 CCH58708.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Antitoxin ParD DUF3810 PF12725.7 CCH58708.1 - 0.54 9.6 6.1 0.99 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF1240 PF06836.12 CCH58708.1 - 2.3 8.8 6.7 7.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) PspB PF06667.12 CCH58708.1 - 3 7.9 7.6 0.51 10.4 0.3 2.9 3 0 0 3 3 3 0 Phage shock protein B BacteriocIIc_cy PF12173.8 CCH58708.1 - 3.5 8.0 11.5 1.3 9.4 0.4 3.8 5 0 0 5 5 5 0 Bacteriocin class IIc cyclic gassericin A-like Kin17_mid PF10357.9 CCH58709.1 - 3.8e-42 143.2 10.0 3.8e-42 143.2 10.0 2.0 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CCH58709.1 - 7.4e-06 26.1 3.2 2.1e-05 24.7 3.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCH58709.1 - 2.6e-05 24.5 4.1 2.6e-05 24.5 4.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CCH58709.1 - 0.00048 20.4 1.3 0.00048 20.4 1.3 2.8 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) TFIID_NTD2 PF04494.15 CCH58709.1 - 0.0045 17.2 2.8 0.0045 17.2 2.8 2.3 2 2 0 2 2 2 1 WD40 associated region in TFIID subunit, NTD2 domain zf-C2H2_4 PF13894.6 CCH58709.1 - 0.051 14.4 5.7 0.17 12.8 2.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH58709.1 - 0.53 10.9 9.1 0.16 12.5 4.7 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF640 PF04852.12 CCH58709.1 - 1.9 8.7 6.3 0.81 9.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF640) FOXP-CC PF16159.5 CCH58709.1 - 5.5 7.7 9.9 5 7.8 0.4 3.5 3 0 0 3 3 3 0 FOXP coiled-coil domain Peptidase_M48 PF01435.18 CCH58710.1 - 1.1e-28 100.3 0.0 2e-28 99.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 MRP-L20 PF12824.7 CCH58711.1 - 2.4e-48 164.4 4.1 3.3e-48 163.9 4.1 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 CCH58711.1 - 0.03 14.3 0.1 0.088 12.8 0.0 1.8 1 1 0 1 1 1 0 Neugrin GTP_EFTU PF00009.27 CCH58712.1 - 5.2e-44 150.1 0.0 7.7e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CCH58712.1 - 1.4e-13 51.0 6.2 3.5e-13 49.7 6.2 1.7 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 CCH58712.1 - 8.1e-08 32.6 0.0 2.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CCH58712.1 - 7.2e-07 29.3 0.0 3.2e-05 24.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CCH58712.1 - 0.00054 20.3 0.0 0.0014 18.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 CCH58712.1 - 0.01 16.0 0.1 2 8.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CCH58712.1 - 0.033 14.1 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Ras PF00071.22 CCH58712.1 - 0.036 13.7 0.1 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 Ras family DUF1854 PF08909.11 CCH58712.1 - 0.045 13.6 0.1 5 6.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1854) Septin PF00735.18 CCH58712.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 CCH58712.1 - 0.1 12.6 0.1 20 5.2 0.0 2.6 1 1 1 2 2 2 0 Dynamin family Syntaxin-18_N PF10496.9 CCH58713.1 - 1.4e-15 57.3 1.1 1.4e-15 57.3 1.1 2.7 3 1 1 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CCH58713.1 - 3.3e-08 33.4 1.2 1.1e-07 31.7 0.7 2.3 1 1 1 2 2 2 1 SNARE domain CD225 PF04505.12 CCH58713.1 - 0.076 13.2 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein SecG PF03840.14 CCH58713.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF2120 PF09893.9 CCH58713.1 - 0.11 12.5 5.7 0.37 10.9 5.1 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Spore_III_AB PF09548.10 CCH58713.1 - 1.1 9.3 6.3 0.68 10.0 0.2 2.8 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Snapin_Pallidin PF14712.6 CCH58713.1 - 2 8.9 20.3 0.068 13.6 4.4 3.6 2 2 1 3 3 3 0 Snapin/Pallidin MCU PF04678.13 CCH58713.1 - 4.6 7.3 8.1 0.32 11.1 0.7 2.4 2 1 0 2 2 2 0 Mitochondrial calcium uniporter DASH_Dad2 PF08654.10 CCH58714.1 - 1.2e-27 96.2 3.7 1.4e-27 96.0 3.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 CCH58714.1 - 0.0039 16.9 3.4 0.006 16.3 3.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 SBDS_C PF09377.10 CCH58714.1 - 0.14 12.2 1.9 0.19 11.8 1.9 1.3 1 1 0 1 1 1 0 SBDS protein C-terminal domain THF_DHG_CYH PF00763.23 CCH58715.1 - 2.3e-25 89.1 0.1 4.4e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CCH58715.1 - 3.5e-18 65.4 0.0 7e-10 38.4 0.0 2.5 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FTP PF07504.13 CCH58715.1 - 0.061 13.2 1.0 0.15 11.9 1.0 1.6 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif DpaA_N PF16924.5 CCH58715.1 - 0.15 12.2 0.0 0.82 9.8 0.0 2.3 1 1 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Lactamase_B_4 PF13691.6 CCH58716.1 - 8.1e-27 92.7 0.0 2e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CCH58716.1 - 1.7e-07 31.0 0.0 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Vps5 PF09325.10 CCH58717.1 - 5.9e-34 117.7 5.5 1e-33 116.9 5.5 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CCH58717.1 - 3.8e-22 78.4 0.7 1.2e-21 76.8 0.2 2.1 2 0 0 2 2 2 1 PX domain DUF5320 PF17253.2 CCH58717.1 - 0.036 15.1 0.3 48 5.1 0.2 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5320) DUF2605 PF10792.9 CCH58717.1 - 0.26 11.2 3.3 4.8 7.2 0.3 3.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2605) Alg6_Alg8 PF03155.15 CCH58718.1 - 2.7e-171 570.8 34.4 3.2e-171 570.6 34.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Cytochrom_C1 PF02167.15 CCH58720.1 - 5.4e-94 314.0 0.0 6.4e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CCH58720.1 - 0.0027 18.0 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CCH58720.1 - 0.066 14.4 0.5 0.22 12.7 0.6 2.0 2 1 0 2 2 2 0 Cytochrome c zf-HC5HC2H PF13771.6 CCH58721.1 - 0.0015 18.8 3.6 0.003 17.8 3.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CCH58721.1 - 0.0062 16.7 3.0 0.012 15.7 3.0 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING-like PF08746.11 CCH58721.1 - 0.15 12.4 6.3 0.27 11.6 0.6 2.4 2 0 0 2 2 2 0 RING-like domain zf-C6H2 PF15801.5 CCH58721.1 - 1.3 9.4 6.7 0.15 12.4 1.6 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Pkinase PF00069.25 CCH58722.1 - 2.4e-58 197.6 0.1 2.9e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58722.1 - 1.7e-15 57.0 0.0 2.5e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCH58722.1 - 1.9e-06 28.0 0.0 5.7e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sld7_N PF18636.1 CCH58723.1 - 1.4e-40 138.5 0.4 2.2e-40 137.9 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Sld7_C PF18596.1 CCH58723.1 - 3.3e-22 78.4 0.1 8.1e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Sld7 C-terminal domain DUF2340 PF10209.9 CCH58724.1 - 7.7e-49 165.1 2.3 9.2e-49 164.9 2.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) PIN_6 PF17146.4 CCH58725.1 - 2.3e-28 98.5 4.1 4e-28 97.8 0.0 3.0 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CCH58725.1 - 5.1e-24 84.2 1.0 1.2e-23 83.0 1.0 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like HypA PF01155.19 CCH58725.1 - 0.001 19.0 0.1 0.0023 17.9 0.1 1.5 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 CCH58725.1 - 0.026 14.8 1.5 0.052 13.8 1.5 1.5 1 0 0 1 1 1 0 zinc-ribbon Zn-ribbon_8 PF09723.10 CCH58725.1 - 0.067 13.3 1.1 0.14 12.3 1.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain WRNPLPNID PF15017.6 CCH58725.1 - 0.98 10.3 20.3 0.25 12.2 8.5 2.8 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box CIAPIN1 PF05093.13 CCH58726.1 - 2.8e-37 127.2 3.1 1.1e-36 125.4 3.1 2.0 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CCH58726.1 - 1.5e-29 102.9 0.5 1.1e-28 100.1 0.1 2.0 2 0 0 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus zf-AN1 PF01428.16 CCH58727.1 - 7.3e-12 45.2 4.5 1.4e-11 44.3 4.5 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.21 CCH58727.1 - 0.083 13.1 6.4 0.15 12.3 6.4 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 CCH58727.1 - 0.088 13.2 5.1 0.14 12.5 5.1 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Hydrolase_6 PF13344.6 CCH58728.1 - 7.6e-24 83.8 0.0 1.5e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCH58728.1 - 5e-22 77.7 0.0 1.1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CCH58728.1 - 0.00016 22.0 0.1 1.6 9.0 0.0 3.0 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCH58728.1 - 0.0012 18.9 0.3 0.023 14.8 0.0 2.7 2 1 2 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCH58728.1 - 0.0035 17.1 2.1 0.27 10.9 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 CCH58728.1 - 0.004 16.9 0.1 0.055 13.2 0.1 2.4 2 2 0 2 2 2 1 Polynucleotide kinase 3 phosphatase TP_methylase PF00590.20 CCH58729.1 - 6.1e-38 130.9 0.0 8.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Shikimate_DH PF01488.20 CCH58729.1 - 0.0098 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 7TMR-HDED PF07697.11 CCH58729.1 - 0.013 15.6 0.4 0.023 14.8 0.4 1.3 1 0 0 1 1 1 0 7TM-HD extracellular TRAPP PF04051.16 CCH58730.1 - 1.8e-34 118.6 0.0 2.1e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3872 PF12988.7 CCH58730.1 - 0.02 14.7 0.2 1.1 9.1 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3872) RTA1 PF04479.13 CCH58731.1 - 2.1e-71 239.8 12.3 3e-71 239.3 12.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Par3_HAL_N_term PF12053.8 CCH58731.1 - 0.15 12.3 2.1 0.27 11.5 2.1 1.3 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins COX2-transmemb PF09125.10 CCH58731.1 - 0.17 11.7 3.2 0.6 9.9 0.4 2.9 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane XRN_M PF17846.1 CCH58733.1 - 3.2e-124 415.3 13.9 1.8e-90 304.0 1.8 3.0 2 1 1 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 CCH58733.1 - 7.9e-98 326.7 0.1 4e-97 324.4 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus STD1 PF17235.2 CCH58734.1 - 4.1e-71 238.9 14.8 4.1e-71 238.9 14.8 3.2 2 1 0 2 2 2 1 STD1/MTH1 Pmp3 PF01679.17 CCH58735.1 - 3e-15 56.2 7.0 3.2e-15 56.0 7.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MNSV_P7B PF06692.11 CCH58736.1 - 0.0034 17.3 3.6 0.52 10.4 0.1 2.3 2 0 0 2 2 2 2 Melon necrotic spot virus P7B protein LpxD PF04613.14 CCH58736.1 - 0.014 15.1 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD CUE PF02845.16 CCH58738.1 - 1e-09 37.9 0.0 2.1e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain Lactamase_B PF00753.27 CCH58739.1 - 8.7e-11 42.2 0.2 7.7e-10 39.1 0.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 CCH58739.1 - 4.1e-08 33.6 0.2 8.7e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 CCH58739.1 - 0.071 12.6 0.4 0.16 11.4 0.4 1.8 1 1 0 1 1 1 0 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.20 CCH58740.1 - 5.1e-45 153.2 0.0 1.3e-44 151.9 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH58740.1 - 3.8e-29 102.5 0.0 2.1e-28 100.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CCH58740.1 - 1.6e-22 79.7 8.1 8.3e-12 45.4 0.1 3.2 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CCH58740.1 - 9.9e-06 25.5 9.0 0.0061 16.3 0.1 4.2 3 1 1 4 4 4 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCH58740.1 - 0.012 15.8 0.4 0.055 13.6 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CK_II_beta PF01214.18 CCH58741.1 - 7.3e-73 244.3 0.0 8.7e-73 244.0 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RecG_N PF17190.4 CCH58741.1 - 0.087 13.6 0.4 0.18 12.6 0.4 1.5 1 0 0 1 1 1 0 RecG N-terminal helical domain CxC5 PF18718.1 CCH58741.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases Hira PF07569.11 CCH58742.1 - 4.4e-82 275.1 0.3 4.4e-82 275.1 0.3 3.0 4 0 0 4 4 4 1 TUP1-like enhancer of split tRNA-synt_1b PF00579.25 CCH58743.1 - 2e-77 260.4 0.0 2.5e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) RAC_head PF16717.5 CCH58743.1 - 0.06 14.3 0.7 0.18 12.8 0.1 2.0 2 0 0 2 2 2 0 Ribosome-associated complex head domain FAD_binding_6 PF00970.24 CCH58744.1 - 0.0012 19.1 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain WD40 PF00400.32 CCH58745.1 - 7.3e-35 118.4 24.9 7.1e-07 29.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58745.1 - 1.7e-12 47.5 4.3 0.012 15.8 0.0 5.1 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CCH58745.1 - 0.073 12.1 3.9 0.19 10.7 0.9 2.6 2 1 1 3 3 3 0 Coatomer WD associated region SH3_9 PF14604.6 CCH58745.1 - 0.1 12.5 0.3 0.36 10.7 0.3 1.9 1 0 0 1 1 1 0 Variant SH3 domain TFB6 PF17110.5 CCH58745.1 - 0.35 10.6 3.5 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH IKI3 PF04762.12 CCH58745.1 - 0.74 7.7 5.3 1.3 6.9 2.1 2.4 2 1 0 2 2 2 0 IKI3 family Syntaxin_2 PF14523.6 CCH58746.1 - 6.2e-17 61.8 11.9 6.2e-17 61.8 11.9 2.8 3 0 0 3 3 3 2 Syntaxin-like protein SNARE PF05739.19 CCH58746.1 - 8.8e-14 51.2 0.1 2.3e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 SNARE domain SKA1 PF07160.12 CCH58746.1 - 0.087 12.7 21.1 0.37 10.6 0.7 3.1 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 Syntaxin PF00804.25 CCH58746.1 - 0.74 9.5 18.0 3.4 7.3 17.3 2.6 1 1 0 1 1 1 0 Syntaxin MCPsignal PF00015.21 CCH58746.1 - 3.5 7.4 18.6 1.2 8.9 6.2 3.1 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 CCH58746.1 - 6.6 7.1 12.7 5.2 7.4 0.2 4.4 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-C3HC4_3 PF13920.6 CCH58747.1 - 2.7e-10 39.9 9.5 2.7e-10 39.9 9.5 3.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH58747.1 - 2.3e-06 27.4 7.3 2.3e-06 27.4 7.3 2.9 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCH58747.1 - 0.00059 19.6 10.8 0.00059 19.6 10.8 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH58747.1 - 0.0025 18.1 9.6 0.0025 18.1 9.6 3.5 4 1 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 CCH58747.1 - 0.94 9.6 9.8 0.22 11.6 5.2 2.5 2 1 0 2 2 2 0 RING-type zinc-finger Pex2_Pex12 PF04757.14 CCH58748.1 - 5.7e-34 117.7 8.9 7.4e-34 117.3 8.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCH58748.1 - 1.7e-07 31.0 17.6 2.6e-07 30.4 17.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH58748.1 - 2.8e-06 27.5 17.6 4.3e-06 27.0 17.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCH58748.1 - 1.5e-05 24.7 16.9 2.4e-05 24.1 16.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH58748.1 - 5.9e-05 22.8 18.1 9.5e-05 22.2 18.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH58748.1 - 0.00016 21.5 16.3 0.00023 20.9 16.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCH58748.1 - 0.00068 19.7 18.1 0.0014 18.7 18.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CCH58748.1 - 0.0031 17.4 13.2 0.0086 16.0 13.3 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CCH58748.1 - 0.0036 17.5 12.2 0.0068 16.7 12.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CCH58748.1 - 0.0045 17.0 10.0 0.0045 17.0 10.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 CCH58748.1 - 0.93 9.4 9.3 1.7 8.5 9.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein XPG_N PF00752.17 CCH58749.1 - 8.8e-30 103.2 0.0 2.8e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCH58749.1 - 6.2e-21 74.6 0.0 3.8e-20 72.0 0.0 2.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCH58749.1 - 1.3e-05 25.7 0.1 8.1e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 CCH58749.1 - 0.015 15.4 0.0 0.73 10.0 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif XPG_I_2 PF12813.7 CCH58749.1 - 0.046 13.2 1.1 0.078 12.4 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing DcpS_C PF11969.8 CCH58750.1 - 5.9e-32 110.5 0.2 5.9e-32 110.5 0.2 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CCH58750.1 - 2.6e-27 95.7 1.2 7.7e-27 94.2 0.2 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Sedlin_N PF04628.13 CCH58750.1 - 0.017 15.3 2.2 0.018 15.1 0.7 1.8 2 0 0 2 2 2 0 Sedlin, N-terminal conserved region YpM PF09144.10 CCH58750.1 - 2.8 8.1 5.0 13 6.0 0.0 3.5 3 1 1 4 4 4 0 Yersinia pseudo-tuberculosis mitogen MBOAT PF03062.19 CCH58751.1 - 2.3e-66 224.5 14.6 2.3e-66 224.5 14.6 2.4 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family nos_propeller PF18764.1 CCH58751.1 - 0.16 11.9 0.1 0.95 9.4 0.0 2.3 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Ferrochelatase PF00762.19 CCH58752.1 - 5.9e-95 318.0 0.0 6.9e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF1664 PF07889.12 CCH58753.1 - 0.68 10.0 8.8 0.09 12.8 3.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CBM_21 PF03370.13 CCH58754.1 - 3.5e-23 81.9 3.9 9.6e-23 80.5 3.9 1.7 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCH58754.1 - 2.3e-06 28.1 5.0 2.4e-06 28.1 1.8 2.5 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) MCM PF00493.23 CCH58755.1 - 4.3e-104 346.5 0.1 7.5e-104 345.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCH58755.1 - 1.1e-36 125.5 0.3 2.4e-36 124.4 0.0 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CCH58755.1 - 4.4e-28 97.5 1.3 1.2e-27 96.1 1.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCH58755.1 - 1.4e-15 57.8 3.0 1.6e-15 57.5 1.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CCH58755.1 - 1.8e-06 28.0 0.0 4.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCH58755.1 - 2.2e-06 27.2 0.0 0.00059 19.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCH58755.1 - 0.00047 20.0 0.0 0.0016 18.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCH58755.1 - 0.034 13.8 0.1 0.99 9.1 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 CCH58755.1 - 1.1 10.0 3.7 3.8 8.2 1.2 3.0 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal LSM PF01423.22 CCH58756.1 - 3.1e-17 62.0 0.4 4e-17 61.7 0.4 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCH58756.1 - 0.093 12.4 0.1 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 Hfq protein DEAD PF00270.29 CCH58757.1 - 1e-38 132.8 1.1 2e-38 131.9 1.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH58757.1 - 1.6e-30 105.7 1.2 6.9e-30 103.6 0.2 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH58757.1 - 2.9e-08 33.9 5.6 5.8e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 CCH58757.1 - 0.0067 17.1 2.6 2.7 8.7 0.2 3.1 2 0 0 2 2 2 2 Primosomal protein DnaI N-terminus CDC45 PF02724.14 CCH58757.1 - 0.0068 14.8 2.8 0.009 14.4 2.8 1.2 1 0 0 1 1 1 1 CDC45-like protein PTPRCAP PF15713.5 CCH58757.1 - 0.0084 16.4 2.4 0.016 15.5 2.4 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated SID-1_RNA_chan PF13965.6 CCH58757.1 - 0.091 11.2 2.3 5.6 5.2 0.0 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 GAGA_bind PF06217.12 CCH58757.1 - 0.15 12.3 3.8 0.053 13.8 0.7 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family DUF3334 PF11813.8 CCH58757.1 - 0.18 11.5 4.6 0.31 10.7 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Afi1 PF07792.12 CCH58757.1 - 4.9 7.6 14.4 11 6.5 0.0 2.9 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CPSF73-100_C PF11718.8 CCH58758.1 - 7.4e-57 192.4 2.4 7.4e-57 192.4 2.4 1.9 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CCH58758.1 - 3.4e-29 101.4 0.0 8.2e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 CCH58758.1 - 5.6e-22 78.7 0.6 9e-22 78.0 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CCH58758.1 - 3.8e-20 72.1 0.0 1.1e-19 70.7 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CCH58758.1 - 1.9e-18 66.1 0.4 4.4e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CCH58758.1 - 4.6e-06 26.3 0.3 5.9e-05 22.7 0.2 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCH58758.1 - 1.1e-05 25.3 0.1 6.3e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CCH58758.1 - 0.001 18.3 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 1 Putative beta-lactamase-like family SecA_DEAD PF07517.14 CCH58758.1 - 0.037 13.3 0.8 0.063 12.6 0.8 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain zf-C2H2_aberr PF17017.5 CCH58758.1 - 0.062 13.4 3.0 0.23 11.6 3.0 2.0 1 0 0 1 1 1 0 Aberrant zinc-finger COPR5 PF15340.6 CCH58758.1 - 0.078 13.6 0.1 0.31 11.7 0.1 2.0 2 0 0 2 2 2 0 Cooperator of PRMT5 family Fungal_trans PF04082.18 CCH58759.1 - 1.6e-09 37.2 11.1 1.6e-09 37.2 11.1 3.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH58759.1 - 2.2e-06 27.7 10.6 4.9e-06 26.6 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 CCH58760.1 - 1e-38 133.3 0.0 1.7e-38 132.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Hus1 PF04005.12 CCH58761.1 - 1.4e-23 83.5 3.1 1.8e-17 63.4 0.5 2.2 2 0 0 2 2 2 2 Hus1-like protein GTP_EFTU PF00009.27 CCH58762.1 - 1.6e-51 174.6 0.0 3.6e-51 173.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CCH58762.1 - 5.1e-36 123.1 6.6 1.6e-35 121.5 6.6 1.9 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CCH58762.1 - 3.7e-10 39.7 0.0 1.4e-08 34.7 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCH58762.1 - 6.8e-08 32.8 3.7 8.5e-08 32.5 0.6 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH58762.1 - 1.1e-05 25.5 0.6 4.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 CCH58762.1 - 0.0002 21.0 1.3 0.00063 19.4 0.0 2.2 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 CCH58762.1 - 0.0027 17.5 0.0 0.0083 16.0 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CCH58762.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 CCH58762.1 - 0.0088 16.0 0.6 0.034 14.2 0.0 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 CCH58762.1 - 0.009 15.5 0.1 0.074 12.5 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit NAT PF04768.13 CCH58762.1 - 0.01 15.5 1.2 0.035 13.8 0.5 2.3 1 1 1 2 2 2 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase ATP_sub_h PF10775.9 CCH58763.1 - 5.2e-18 64.8 0.6 7.4e-18 64.3 0.6 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-U1 PF06220.12 CCH58764.1 - 6.7e-18 64.2 6.0 1.5e-17 63.0 6.0 1.6 1 0 0 1 1 1 1 U1 zinc finger GTP_EFTU PF00009.27 CCH58765.1 - 9.5e-59 198.2 0.2 1.3e-58 197.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCH58765.1 - 1.3e-27 96.3 0.0 2.5e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCH58765.1 - 2.7e-21 75.8 2.3 6.6e-21 74.5 2.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH58765.1 - 5.1e-05 23.3 0.1 0.0001 22.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CCH58765.1 - 0.019 14.6 0.9 0.027 14.1 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CCH58765.1 - 0.032 14.1 0.1 0.067 13.1 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CCH58765.1 - 0.069 12.9 0.2 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G_glu_transpept PF01019.21 CCH58766.1 - 5e-135 451.2 0.0 6.3e-135 450.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1708 PF08101.11 CCH58767.1 - 1.2e-102 344.3 8.8 4.3e-88 296.3 1.8 4.0 2 2 1 4 4 4 2 Domain of unknown function (DUF1708) FAM150 PF15129.6 CCH58768.1 - 0.51 10.5 2.9 0.35 11.0 0.3 1.8 1 1 1 2 2 2 0 FAM150 family CNDH2_M PF16869.5 CCH58768.1 - 6.4 7.5 8.7 10 6.8 8.6 1.6 1 1 0 1 1 1 0 PF16858 Cellulase PF00150.18 CCH58769.1 - 5.9e-11 42.3 0.4 9.8e-11 41.6 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.23 CCH58771.1 - 3.6e-54 183.8 0.5 1.2e-53 182.0 0.1 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH58771.1 - 1.6e-16 60.6 0.3 1.6e-16 60.6 0.3 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CCH58771.1 - 0.0001 22.2 0.7 0.0003 20.8 0.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCH58771.1 - 0.00014 21.7 3.7 0.00041 20.3 3.7 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCH58771.1 - 0.00043 20.1 2.1 0.00043 20.1 2.1 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 ResIII PF04851.15 CCH58771.1 - 0.00097 19.2 0.0 0.00097 19.2 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 CCH58771.1 - 0.0016 18.8 4.5 0.0046 17.3 4.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCH58771.1 - 0.0027 17.5 0.7 0.0027 17.5 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sprouty PF05210.13 CCH58771.1 - 0.042 14.2 5.6 13 6.3 0.0 3.5 3 0 0 3 3 3 0 Sprouty protein (Spry) zf-C3HC4_2 PF13923.6 CCH58771.1 - 0.066 13.1 1.0 0.17 11.7 1.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH58771.1 - 0.13 12.2 8.7 0.021 14.7 4.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH58771.1 - 0.27 11.4 5.7 0.84 9.8 5.0 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Cornichon PF03311.14 CCH58772.1 - 1.5e-46 157.7 10.8 1.7e-46 157.5 10.8 1.0 1 0 0 1 1 1 1 Cornichon protein Sigma_reg_N PF13800.6 CCH58772.1 - 0.093 13.0 0.6 0.36 11.2 0.0 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Hexapep PF00132.24 CCH58773.1 - 0.098 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) RRM_1 PF00076.22 CCH58774.1 - 2.7e-30 104.0 0.0 1.4e-15 56.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FYTT PF07078.11 CCH58774.1 - 0.019 14.3 2.6 0.037 13.4 2.6 1.4 1 0 0 1 1 1 0 Forty-two-three protein OHA PF14418.6 CCH58774.1 - 0.13 12.1 0.5 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 OST-HTH Associated domain CBS PF00571.28 CCH58775.1 - 6.2e-20 71.4 1.0 1.3e-05 25.6 0.0 5.1 5 0 0 5 5 5 4 CBS domain HUN PF08729.10 CCH58776.1 - 4.1e-07 29.9 0.0 4.1e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 HPC2 and ubinuclein domain YlzJ PF14035.6 CCH58776.1 - 0.0054 16.9 0.6 0.05 13.8 0.0 2.7 3 0 0 3 3 3 1 YlzJ-like protein Kinetochor_Ybp2 PF08568.10 CCH58777.1 - 7.8e-130 434.3 27.4 8.8e-130 434.1 27.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin COX4 PF02936.14 CCH58777.1 - 0.063 13.3 0.4 3.9 7.5 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV APG12 PF04110.13 CCH58778.1 - 9.4e-30 102.9 0.3 1.7e-29 102.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CCH58778.1 - 0.014 15.6 0.2 0.3 11.3 0.2 2.2 1 1 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like CPSase_L_D2 PF02786.17 CCH58779.1 - 2.1e-83 279.0 0.1 3.6e-83 278.2 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCH58779.1 - 1.2e-69 234.1 0.0 2.2e-69 233.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CCH58779.1 - 5.9e-39 133.0 0.1 1.1e-38 132.1 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCH58779.1 - 1.7e-30 105.3 0.0 1e-29 102.8 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCH58779.1 - 1.1e-24 87.4 0.0 2.2e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CCH58779.1 - 8.3e-19 67.2 2.9 8.3e-19 67.2 2.9 2.8 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCH58779.1 - 1.7e-09 37.3 1.7 0.001 18.9 0.4 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CCH58779.1 - 1.6e-07 31.1 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CCH58779.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_D23 PF16576.5 CCH58779.1 - 6.1e-05 22.3 0.7 0.13 11.5 0.1 2.7 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 CCH58779.1 - 0.00016 21.8 0.0 0.00032 20.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CCH58779.1 - 0.00055 20.6 0.7 0.39 11.5 0.1 3.1 2 0 0 2 2 2 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 CCH58779.1 - 0.0035 16.6 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 CCH58779.1 - 0.019 14.6 0.0 0.048 13.3 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain RnfC_N PF13375.6 CCH58779.1 - 0.02 14.8 1.1 0.21 11.5 0.2 2.7 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.11 CCH58779.1 - 0.069 12.6 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RimK PF08443.11 CCH58779.1 - 0.078 12.6 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain YqfD PF06898.11 CCH58779.1 - 0.28 10.0 0.6 0.7 8.7 0.6 1.6 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD GCV_H PF01597.19 CCH58779.1 - 0.31 10.9 1.6 2.3 8.1 0.5 2.5 2 0 0 2 2 2 0 Glycine cleavage H-protein Transket_pyr PF02779.24 CCH58780.1 - 1.5e-45 155.1 0.0 4.7e-45 153.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCH58780.1 - 6.2e-38 129.5 0.0 1.4e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain AMP-binding PF00501.28 CCH58781.1 - 2.1e-75 253.9 0.0 2.7e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCH58781.1 - 2.5e-13 50.8 0.0 5.8e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RTX_C PF08339.10 CCH58781.1 - 0.093 12.8 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 RTX C-terminal domain Tyr-DNA_phospho PF06087.12 CCH58782.1 - 4.2e-73 246.7 0.5 5.7e-73 246.2 0.5 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CCH58782.1 - 0.04 13.8 0.7 0.24 11.3 0.0 2.5 3 1 0 3 3 3 0 PLD-like domain Methyltransf_11 PF08241.12 CCH58783.1 - 0.00097 19.7 0.0 0.0025 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH58783.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH58783.1 - 0.058 14.1 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_31 PF01055.26 CCH58784.1 - 4.3e-129 431.5 1.3 8.6e-129 430.6 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CCH58784.1 - 2e-23 82.5 0.6 2.8e-22 78.8 0.2 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CCH58784.1 - 0.0038 17.5 0.0 0.016 15.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Lectin_C PF00059.21 CCH58784.1 - 0.011 16.5 0.7 6.1 7.6 0.3 2.8 2 0 0 2 2 2 0 Lectin C-type domain DUF5353 PF17304.2 CCH58785.1 - 0.033 13.9 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5353) NiFeSe_Hases PF00374.19 CCH58786.1 - 0.099 11.5 0.0 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase ABC1 PF03109.16 CCH58787.1 - 4.5e-33 114.0 0.0 1.2e-32 112.5 0.0 1.8 1 0 0 1 1 1 1 ABC1 family LptF_LptG PF03739.14 CCH58787.1 - 0.025 13.5 0.5 0.053 12.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG PPTA PF01239.22 CCH58787.1 - 0.058 13.1 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat EMC1_C PF07774.13 CCH58787.1 - 0.068 12.9 0.2 0.91 9.2 0.0 2.4 3 0 0 3 3 3 0 ER membrane protein complex subunit 1, C-terminal FAD_binding_2 PF00890.24 CCH58788.1 - 3e-122 408.7 2.3 4.8e-122 408.0 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CCH58788.1 - 2.3e-44 150.5 0.4 4.1e-44 149.7 0.4 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 CCH58788.1 - 7.1e-06 25.3 2.5 0.0035 16.5 2.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 CCH58788.1 - 2.3e-05 23.8 0.5 0.0029 16.9 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 CCH58788.1 - 6.6e-05 22.3 0.9 0.00018 20.8 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CCH58788.1 - 0.003 16.9 0.1 0.0063 15.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCH58788.1 - 0.0031 17.2 1.3 0.0099 15.5 1.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCH58788.1 - 0.034 12.9 0.1 0.18 10.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 CCH58788.1 - 0.29 11.4 1.4 0.72 10.1 0.4 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CCH58788.1 - 1.6 7.9 5.3 4.1 6.6 1.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_6 PF00970.24 CCH58789.1 - 6.1e-26 90.7 0.0 1.1e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCH58789.1 - 2.4e-23 82.9 0.0 3.4e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCH58789.1 - 0.0013 18.9 0.0 0.0078 16.3 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain SH3_13 PF18335.1 CCH58789.1 - 0.024 14.4 0.1 0.047 13.5 0.1 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Carb_kinase PF01256.17 CCH58790.1 - 2.8e-58 197.3 0.1 4e-58 196.8 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CCH58790.1 - 1.7e-06 27.6 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase LRR_6 PF13516.6 CCH58791.1 - 0.008 16.2 5.6 11 6.4 0.2 6.2 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 CCH58791.1 - 2.9 8.8 8.0 17 6.5 0.0 5.9 4 0 0 4 4 4 0 Leucine Rich Repeat Nup192 PF11894.8 CCH58792.1 - 0 1620.1 83.0 0 1619.9 83.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Integrase_H2C2 PF17921.1 CCH58793.1 - 9.6e-19 67.2 0.3 1.8e-18 66.3 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 CCH58793.1 - 1.6e-06 28.3 0.1 4.3e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-H2C2 PF09337.10 CCH58793.1 - 0.00014 22.0 0.0 0.00034 20.8 0.0 1.7 1 0 0 1 1 1 1 H2C2 zinc finger PIP5K PF01504.18 CCH58794.1 - 7.7e-44 150.0 6.4 5e-36 124.3 2.1 3.6 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CCH58794.1 - 3.8e-26 91.8 0.1 7e-26 90.9 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CCH58794.1 - 3.6e-17 62.3 10.9 3.6e-17 62.3 10.9 2.6 3 0 0 3 3 3 1 FYVE zinc finger Peptidase_M28 PF04389.17 CCH58795.1 - 1.1e-39 136.1 0.0 1.6e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nucleoporin_FG PF13634.6 CCH58796.1 - 7.3e-51 171.0 362.3 3.6e-12 47.0 34.2 12.8 4 2 9 13 13 13 10 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CCH58796.1 - 6.5e-27 94.5 0.0 1.4e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Swi3 PF07962.12 CCH58797.1 - 2.9e-26 91.2 0.5 8.9e-26 89.7 0.3 1.9 1 1 1 2 2 2 1 Replication Fork Protection Component Swi3 DUF5601 PF18151.1 CCH58797.1 - 0.079 13.3 1.1 0.82 10.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) Ribosomal_L28e PF01778.17 CCH58797.1 - 0.88 10.3 8.3 1.5 9.6 7.5 1.8 1 1 0 1 1 1 0 Ribosomal L28e protein family BOP1NT PF08145.12 CCH58798.1 - 5.1e-103 344.5 8.3 9.4e-103 343.7 8.3 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CCH58798.1 - 4.6e-24 84.2 9.6 4e-10 40.1 0.7 6.7 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH58798.1 - 1.4e-07 31.7 1.1 0.17 12.2 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain GAF_2 PF13185.6 CCH58799.1 - 1.2e-09 38.5 0.0 1.6e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CCH58799.1 - 3.2e-06 27.8 0.0 3.7e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CCH58799.1 - 0.0062 16.9 0.0 0.013 15.9 0.0 1.5 2 0 0 2 2 2 1 GAF domain Scramblase PF03803.15 CCH58800.1 - 2.3e-69 233.1 0.4 3.2e-69 232.6 0.4 1.2 1 0 0 1 1 1 1 Scramblase SRX PF09201.10 CCH58801.1 - 4.5e-63 211.5 6.3 1e-62 210.3 6.3 1.7 1 0 0 1 1 1 1 SRX, signal recognition particle receptor alpha subunit SRP54 PF00448.22 CCH58801.1 - 4.2e-48 163.6 0.6 2.3e-45 154.7 0.6 2.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 CCH58801.1 - 6.4e-06 25.4 0.0 3e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 CCH58801.1 - 9.5e-06 25.8 0.2 3.7e-05 23.9 0.2 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_31 PF13614.6 CCH58801.1 - 0.00023 21.1 0.1 0.0024 17.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CCH58801.1 - 0.0017 17.6 4.1 0.033 13.4 0.0 3.3 3 0 0 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CCH58801.1 - 0.0022 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CbiA PF01656.23 CCH58801.1 - 0.0022 18.0 0.3 0.023 14.8 0.0 2.8 3 2 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 CCH58801.1 - 0.01 15.5 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCH58801.1 - 0.027 14.8 0.1 0.18 12.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCH58801.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCH58801.1 - 0.13 12.4 0.2 0.43 10.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CCH58801.1 - 3.1 7.8 12.4 3.5 7.7 0.2 3.6 4 0 0 4 4 4 0 Helicase HerA, central domain DEAD PF00270.29 CCH58802.1 - 9.1e-24 84.2 0.0 4.7e-23 81.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 CCH58802.1 - 5.1e-19 68.8 0.2 1.4e-18 67.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CCH58802.1 - 6.1e-14 52.3 0.2 2.4e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH58802.1 - 2.1e-09 37.6 0.1 5.3e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CCH58802.1 - 0.00082 19.7 0.7 0.002 18.5 0.7 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF1548 PF07579.11 CCH58802.1 - 0.087 13.2 0.1 0.35 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) Terminase_GpA PF05876.12 CCH58802.1 - 0.14 10.7 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) PAP2 PF01569.21 CCH58803.1 - 2.1e-23 82.6 0.7 3.7e-23 81.8 0.2 1.6 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CCH58803.1 - 0.021 14.5 6.6 0.4 10.4 6.6 2.3 1 1 0 1 1 1 0 PAP2 superfamily RseC_MucC PF04246.12 CCH58803.1 - 0.17 11.8 4.4 0.079 12.9 1.5 1.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TMF_TATA_bd PF12325.8 CCH58804.1 - 0.006 16.8 9.5 0.006 16.8 9.5 6.8 2 2 5 7 7 7 1 TATA element modulatory factor 1 TATA binding DUF3641 PF12345.8 CCH58804.1 - 1.4 9.0 8.0 1.2 9.1 4.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) DUF836 PF05768.14 CCH58805.1 - 1.3e-16 60.8 0.7 1.8e-16 60.3 0.7 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CCH58805.1 - 0.00041 20.5 0.0 0.00069 19.8 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin Inositol_P PF00459.25 CCH58806.1 - 3e-64 217.2 0.0 3.6e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF327 PF03885.13 CCH58806.1 - 0.029 14.3 0.4 0.054 13.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF327) FAD_binding_1 PF00667.20 CCH58807.1 - 2.3e-68 230.1 0.0 4.2e-68 229.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCH58807.1 - 1.7e-28 99.6 0.8 2.9e-28 98.9 0.8 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCH58807.1 - 8.1e-22 77.9 0.0 1.7e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RAG2_PHD PF13341.6 CCH58807.1 - 0.036 14.1 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RAG2 PHD domain HAD_2 PF13419.6 CCH58808.1 - 1.6e-16 60.9 0.0 2.4e-16 60.3 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCH58808.1 - 1.2e-07 32.3 0.0 1.1e-06 29.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 CCH58809.1 - 2.9e-21 76.4 0.0 4.5e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCH58809.1 - 1e-18 67.1 0.9 2.7e-17 62.5 0.1 2.7 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 TFB6 PF17110.5 CCH58810.1 - 0.03 14.1 0.1 0.062 13.0 0.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Inositol_P PF00459.25 CCH58811.1 - 4.8e-65 219.8 0.0 5.3e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF327 PF03885.13 CCH58811.1 - 0.076 13.0 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF327) Peptidase_M1 PF01433.20 CCH58812.1 - 2.9e-87 291.8 3.5 2.9e-87 291.8 3.5 1.8 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CCH58812.1 - 4e-83 279.6 1.9 2.2e-81 273.9 1.2 2.5 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CCH58812.1 - 2e-53 181.4 2.3 2e-53 181.4 2.3 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 CCH58812.1 - 0.034 14.5 0.1 2.2 8.8 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats VMR2 PF17055.5 CCH58812.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral matrix protein M2 MFS_1 PF07690.16 CCH58813.1 - 3.2e-36 125.0 40.4 3.2e-36 125.0 40.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58813.1 - 2.3e-10 40.0 10.0 2.3e-10 40.0 10.0 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter DUF1269 PF06897.12 CCH58813.1 - 0.63 10.4 4.3 8.7 6.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) DUF3937 PF13073.6 CCH58813.1 - 2.2 8.5 6.0 0.89 9.7 0.7 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3937) FSH1 PF03959.13 CCH58814.1 - 3.3e-62 209.9 0.0 3.7e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCH58814.1 - 0.0096 15.7 0.1 0.24 11.2 0.1 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CCH58814.1 - 0.013 15.4 0.0 1.4 8.8 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Calcipressin PF04847.12 CCH58815.1 - 7.7e-21 74.7 0.2 1.2e-19 70.8 0.2 2.0 1 1 0 1 1 1 1 Calcipressin NadA PF02445.16 CCH58815.1 - 0.03 13.5 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Quinolinate synthetase A protein Elf1 PF05129.13 CCH58816.1 - 2.7e-29 101.0 1.1 3.5e-29 100.7 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L1 PF00687.21 CCH58817.1 - 8.7e-37 126.8 5.3 1.7e-36 125.9 5.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MatE PF01554.18 CCH58818.1 - 1.2e-66 223.4 33.8 2.8e-39 134.4 9.8 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CCH58818.1 - 2.2e-07 31.0 31.4 4.7e-06 26.7 9.8 3.5 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain ADH_zinc_N_2 PF13602.6 CCH58819.1 - 6e-10 40.3 0.0 1.4e-09 39.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCH58819.1 - 2.7e-06 27.4 0.0 5.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH58819.1 - 0.0024 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.25 CCH58820.1 - 5.5e-65 219.3 0.9 7.9e-65 218.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58820.1 - 3.1e-31 108.6 0.8 5e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH58820.1 - 8.3e-05 21.7 0.6 8.3e-05 21.7 0.6 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Spt20 PF12090.8 CCH58820.1 - 0.0056 16.3 13.2 0.0096 15.6 13.2 1.3 1 0 0 1 1 1 1 Spt20 family APH PF01636.23 CCH58820.1 - 0.012 15.6 1.1 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CCH58820.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RolB_RolC PF02027.17 CCH58820.1 - 0.052 13.2 2.9 0.091 12.4 2.9 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family DPPIV_N PF00930.21 CCH58821.1 - 4.8e-102 341.4 11.9 4.8e-102 341.4 11.9 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CCH58821.1 - 1.4e-50 171.8 0.8 2.6e-50 170.8 0.8 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CCH58821.1 - 0.004 17.8 0.0 0.0073 16.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCH58821.1 - 0.021 14.5 0.2 0.096 12.3 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold ATP-synt_C PF00137.21 CCH58822.1 - 3.9e-25 88.0 32.8 4.9e-17 62.0 12.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 CCH58822.1 - 0.27 10.9 9.6 0.026 14.2 2.1 2.5 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF3671 PF12420.8 CCH58822.1 - 1.5 8.9 10.0 0.46 10.6 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function GHMP_kinases_N PF00288.26 CCH58823.1 - 2e-10 40.8 0.0 3.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCH58823.1 - 0.00018 21.8 0.0 0.00056 20.2 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16 PF00675.20 CCH58824.1 - 1e-42 145.6 0.2 3.8e-41 140.5 0.0 2.6 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCH58824.1 - 1.3e-34 119.9 0.0 6.9e-34 117.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Chlorosome_CsmC PF11098.8 CCH58824.1 - 0.011 15.8 0.0 6.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Chlorosome envelope protein C Myosin_head PF00063.21 CCH58825.1 - 5e-245 814.9 28.2 5e-245 814.9 28.2 3.9 3 1 0 4 4 4 1 Myosin head (motor domain) Phage_GP20 PF06810.11 CCH58825.1 - 0.00095 19.0 10.4 0.00095 19.0 10.4 15.4 3 2 12 16 16 16 4 Phage minor structural protein GP20 Myosin_N PF02736.19 CCH58825.1 - 0.0061 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CCH58825.1 - 0.75 10.1 0.0 0.75 10.1 0.0 4.5 3 1 1 4 4 4 0 AAA domain Ras PF00071.22 CCH58826.1 - 4.6e-16 58.8 0.3 1.5e-14 53.9 0.3 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CCH58826.1 - 0.00014 22.0 0.1 0.0023 18.1 0.0 2.5 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF5623 PF18536.1 CCH58826.1 - 0.091 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) SRPRB PF09439.10 CCH58827.1 - 2.7e-58 196.4 0.4 4.1e-58 195.8 0.4 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCH58827.1 - 3.4e-09 36.8 0.2 7.5e-09 35.7 0.2 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 CCH58827.1 - 1.3e-08 34.5 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH58827.1 - 1.9e-07 30.7 0.2 2.7e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCH58827.1 - 9.5e-05 22.0 0.0 0.11 12.0 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CCH58827.1 - 0.00089 19.1 0.2 0.006 16.4 0.1 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CCH58827.1 - 0.0015 18.5 0.5 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CCH58827.1 - 0.0019 17.7 0.1 0.0041 16.7 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CCH58827.1 - 0.097 12.4 0.0 0.31 10.8 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation HIM1 PF08732.10 CCH58828.1 - 4.7e-13 49.0 0.0 6.9e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.21 CCH58828.1 - 2.7e-06 27.1 0.0 5.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CCH58828.1 - 0.00055 19.9 0.0 0.0018 18.2 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CCH58828.1 - 0.036 14.5 0.1 0.18 12.3 0.1 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arrestin_C PF02752.22 CCH58829.1 - 1.8e-26 93.2 0.7 4.8e-25 88.6 0.1 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCH58829.1 - 2.8e-09 37.2 0.0 2.5e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCH58829.1 - 0.00036 20.3 0.1 0.00094 18.9 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like TIP120 PF08623.10 CCH58830.1 - 1e-05 25.3 0.1 5.8e-05 22.9 0.1 2.3 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) DUF3136 PF11334.8 CCH58830.1 - 0.079 12.8 0.0 21 5.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) Rho_N PF07498.12 CCH58831.1 - 0.048 13.6 0.2 0.1 12.5 0.2 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Tmemb_170 PF10190.9 CCH58831.1 - 0.39 11.1 1.9 0.34 11.3 0.5 1.6 2 0 0 2 2 2 0 Putative transmembrane protein 170 MFS_1 PF07690.16 CCH58832.1 - 2.6e-26 92.4 28.2 2.6e-26 92.4 28.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH58832.1 - 7.5e-09 35.0 34.8 5.3e-08 32.2 5.9 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CCH58832.1 - 0.013 14.4 25.0 0.012 14.5 8.5 2.4 2 0 0 2 2 2 0 MFS_1 like family Oxidored_FMN PF00724.20 CCH58833.1 - 8e-125 416.6 0.0 9.2e-125 416.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NCBP3 PF10309.9 CCH58833.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 Syntaxin-6_N PF09177.11 CCH58834.1 - 0.042 14.4 0.7 0.042 14.4 0.7 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TMF_TATA_bd PF12325.8 CCH58836.1 - 8.1e-33 113.1 22.2 8.1e-33 113.1 22.2 5.9 2 1 3 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CCH58836.1 - 7e-06 25.9 20.8 7e-06 25.9 20.8 10.7 4 3 8 12 12 12 2 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 CCH58836.1 - 0.006 16.3 22.2 0.006 16.3 22.2 5.4 2 1 1 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease TMEM132D_C PF15706.5 CCH58838.1 - 0.14 11.9 0.4 0.6 9.9 0.4 2.0 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Pex14_N PF04695.13 CCH58839.1 - 2.8e-26 93.1 6.0 2.8e-26 93.1 6.0 3.6 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region HAP1_N PF04849.13 CCH58839.1 - 0.0011 18.3 12.5 0.002 17.4 12.5 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4535 PF15054.6 CCH58839.1 - 0.088 12.6 0.0 1.4 8.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) Fibin PF15819.5 CCH58839.1 - 0.15 11.9 4.9 0.31 10.8 4.9 1.6 1 0 0 1 1 1 0 Fin bud initiation factor homologue BCAS2 PF05700.11 CCH58839.1 - 0.45 10.2 12.5 0.078 12.7 8.2 2.0 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) SlyX PF04102.12 CCH58839.1 - 2.3 8.9 8.0 0.57 10.8 1.7 3.0 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.12 CCH58839.1 - 3.4 7.7 14.3 83 3.2 12.4 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 CCH58839.1 - 4.5 6.4 12.4 1.1 8.4 7.8 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein ATP-synt_E PF05680.12 CCH58839.1 - 7.9 6.9 11.0 0.27 11.6 2.4 2.9 3 0 0 3 3 3 0 ATP synthase E chain Rx_N PF18052.1 CCH58839.1 - 8.5 6.7 12.3 22 5.4 7.2 2.8 1 1 1 2 2 2 0 Rx N-terminal domain DUF4984 PF16372.5 CCH58840.1 - 0.031 14.2 1.3 0.093 12.7 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4984) NIR_SIR PF01077.22 CCH58841.1 - 4.6e-55 185.5 0.0 2.4e-47 160.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CCH58841.1 - 9.7e-26 89.4 0.1 2.1e-13 49.9 0.0 3.1 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CCH58841.1 - 1.2e-24 87.2 0.0 2.3e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Chalcone_2 PF16035.5 CCH58842.1 - 1e-52 178.9 0.0 1.3e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 CCH58842.1 - 0.0034 17.5 1.1 0.38 10.9 0.1 2.2 1 1 0 2 2 2 2 Chalcone isomerase-like VWA_2 PF13519.6 CCH58843.1 - 5e-20 72.1 0.9 1.5e-19 70.6 0.1 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 CCH58843.1 - 7.8e-10 38.9 0.3 1.2e-09 38.3 0.3 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 CCH58843.1 - 2.8e-07 31.0 0.6 4e-07 30.5 0.6 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 CCH58843.1 - 0.025 14.5 1.1 0.069 13.1 1.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosomal_S18 PF01084.20 CCH58843.1 - 0.089 13.0 0.1 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S18 DUF4743 PF15916.5 CCH58844.1 - 1.2e-06 28.4 0.0 2.1e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CCH58844.1 - 9.2e-06 25.7 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PMT PF02366.18 CCH58845.1 - 2.4e-85 286.0 23.0 2.4e-85 286.0 23.0 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCH58845.1 - 2.7e-60 203.4 8.1 2.7e-60 203.4 8.1 3.3 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCH58845.1 - 2.9e-20 72.9 0.5 4.9e-20 72.1 0.5 1.3 1 0 0 1 1 1 1 MIR domain PHO4 PF01384.20 CCH58845.1 - 0.087 11.9 1.1 2.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Phosphate transporter family Mgm101p PF06420.12 CCH58846.1 - 9.1e-86 285.7 0.0 1.2e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Pkinase PF00069.25 CCH58847.1 - 6.9e-67 225.6 0.0 1.2e-66 224.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58847.1 - 3.2e-31 108.6 0.0 5.7e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCH58847.1 - 2.9e-10 40.7 2.9 2.9e-10 40.7 2.9 3.2 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.6 CCH58847.1 - 3.2e-09 36.5 0.0 1.1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CCH58847.1 - 0.031 13.9 0.1 0.99 9.0 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HSF_DNA-bind PF00447.17 CCH58848.1 - 9.1e-29 99.9 3.9 2.3e-28 98.6 2.4 2.2 2 1 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 CCH58848.1 - 1.6e-27 95.9 0.2 5.2e-27 94.2 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain SHE3 PF17078.5 CCH58848.1 - 0.032 14.0 3.7 0.063 13.0 3.7 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 3HCDH_RFF PF18321.1 CCH58848.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.5 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Bap31_Bap29_C PF18035.1 CCH58848.1 - 0.5 10.4 2.1 0.96 9.5 2.1 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain 5-FTHF_cyc-lig PF01812.20 CCH58849.1 - 1.9e-36 125.6 0.0 3e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.19 CCH58850.1 - 4.1e-33 115.1 0.0 5e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Flocculin PF00624.18 CCH58851.1 - 2.4e-15 56.5 116.7 1.6e-09 37.9 15.4 28.4 27 4 4 31 31 31 12 Flocculin repeat GLEYA PF10528.9 CCH58851.1 - 2.9e-12 46.8 6.2 4.8e-11 42.9 0.5 4.5 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 CCH58851.1 - 2.1e-10 40.6 0.0 2.8e-09 36.9 0.0 3.1 1 0 0 1 1 1 1 PA14 domain Urm1 PF09138.11 CCH58851.1 - 0.14 12.5 0.3 0.52 10.7 0.3 1.9 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Flocculin PF00624.18 CCH58852.1 - 2.3e-34 117.3 85.0 8.3e-12 45.2 19.9 12.1 11 1 2 13 13 13 4 Flocculin repeat GLEYA PF10528.9 CCH58852.1 - 1.5e-12 47.8 0.3 5e-11 42.9 0.3 4.1 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 CCH58852.1 - 2.3e-06 27.5 0.1 7.1e-06 25.9 0.1 1.9 1 0 0 1 1 1 1 PA14 domain Zn_clus PF00172.18 CCH58853.1 - 1.2e-07 31.8 10.4 2.2e-07 30.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T3SchapCesA PF11439.8 CCH58853.1 - 0.013 15.7 0.9 0.04 14.0 0.3 2.2 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA Transp_cyt_pur PF02133.15 CCH58854.1 - 1.4e-71 241.6 33.9 1.9e-71 241.2 33.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATG_C PF09333.11 CCH58855.1 - 2e-30 105.0 0.0 5.1e-30 103.7 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 CCH58855.1 - 7e-30 103.8 1.0 7e-30 103.8 1.0 3.6 4 0 0 4 4 4 1 Autophagy-related protein 2 CAD motif Fe_hyd_lg_C PF02906.14 CCH58856.1 - 1.1e-59 202.0 0.0 1.6e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAM194 PF14977.6 CCH58856.1 - 0.066 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 FAM194 protein Peptidase_C1_2 PF03051.15 CCH58857.1 - 3.9e-164 546.6 3.3 5e-164 546.3 3.3 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CCH58857.1 - 0.00021 21.4 1.0 0.44 10.6 0.0 3.1 3 1 0 3 3 3 2 Papain family cysteine protease Peptidase_S8 PF00082.22 CCH58858.1 - 1.6e-38 132.7 0.1 2.6e-38 132.0 0.1 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CCH58858.1 - 4.5e-25 87.5 0.7 4.4e-24 84.3 0.3 2.5 2 0 0 2 2 2 1 Proprotein convertase P-domain RIC3 PF15361.6 CCH58858.1 - 0.00094 19.6 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 Pex14_N PF04695.13 CCH58858.1 - 0.0025 18.5 0.2 0.0053 17.4 0.2 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PBP1_TM PF14812.6 CCH58858.1 - 0.06 13.7 0.2 3.6 8.0 0.0 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2370 PF10176.9 CCH58858.1 - 0.069 12.8 0.2 0.14 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Orf78 PF06024.12 CCH58858.1 - 0.11 12.8 0.9 0.28 11.5 0.1 2.0 1 1 1 2 2 2 0 Orf78 (ac78) Cupin_8 PF13621.6 CCH58859.1 - 0.15 11.8 8.1 0.19 11.4 8.1 1.2 1 0 0 1 1 1 0 Cupin-like domain MAP70 PF07058.11 CCH58859.1 - 0.25 10.0 4.1 0.3 9.8 4.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 Med16 PF11635.8 CCH58860.1 - 3.6e-177 590.6 27.9 4.3e-177 590.4 27.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Clathrin_bdg PF15045.6 CCH58860.1 - 0.0018 18.2 1.5 0.0069 16.4 1.5 2.0 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking DUF489 PF04356.12 CCH58860.1 - 0.55 10.2 5.0 0.59 10.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Globin PF00042.22 CCH58861.1 - 0.015 15.8 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 Globin EXOSC1 PF10447.9 CCH58863.1 - 1.1e-38 132.2 0.0 2.2e-38 131.2 0.0 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 CRAL_TRIO PF00650.20 CCH58864.1 - 3.1e-38 131.0 0.0 5.3e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH58864.1 - 1.8e-16 60.1 0.1 6.4e-16 58.3 0.1 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF936 PF06075.12 CCH58864.1 - 1.7 7.5 43.4 2.1 7.2 43.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Elongin_A PF06881.11 CCH58865.1 - 8.2e-16 58.4 11.1 1.6e-15 57.5 6.5 2.9 2 1 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_C PF00043.25 CCH58866.1 - 2.5e-24 85.3 0.0 4.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCH58866.1 - 5.6e-20 71.5 0.0 1.3e-19 70.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CCH58866.1 - 3.9e-10 39.9 0.0 7.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CCH58866.1 - 1.5e-09 38.1 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCH58866.1 - 8.8e-06 25.8 0.0 1.9e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH58866.1 - 0.0042 17.1 0.0 0.0087 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SID PF11778.8 CCH58867.1 - 1.8e-39 135.0 9.1 1.8e-39 135.0 9.1 2.7 3 1 0 3 3 3 1 Septation initiation BRE1 PF08647.11 CCH58867.1 - 0.0094 16.0 26.4 0.0094 16.0 26.4 4.7 1 1 3 4 4 4 1 BRE1 E3 ubiquitin ligase MbeD_MobD PF04899.12 CCH58867.1 - 0.34 11.1 0.1 0.34 11.1 0.1 3.4 2 1 2 4 4 4 0 MbeD/MobD like DUF1515 PF07439.11 CCH58867.1 - 0.79 9.8 13.7 0.39 10.8 2.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) YvrJ PF12841.7 CCH58867.1 - 0.89 9.1 3.0 1.2 8.8 0.2 2.7 2 0 0 2 2 2 0 YvrJ protein family DUF963 PF06131.11 CCH58867.1 - 1.6 8.3 3.9 3.7 7.0 3.9 1.6 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF1192 PF06698.11 CCH58867.1 - 1.7 8.7 8.2 2.6 8.1 1.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) G-patch PF01585.23 CCH58868.1 - 9.2e-10 38.3 2.2 2.2e-09 37.1 2.2 1.7 1 0 0 1 1 1 1 G-patch domain Gryzun-like PF12742.7 CCH58868.1 - 0.079 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Rap1-DNA-bind PF09197.10 CCH58869.1 - 8.6e-38 129.3 5.8 2.6e-34 118.1 0.3 3.5 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.8 CCH58869.1 - 3.8e-23 81.4 0.0 1.9e-22 79.1 0.0 2.3 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.31 CCH58869.1 - 2.7e-14 53.1 2.8 1.9e-10 40.8 0.0 4.1 4 1 0 4 4 4 2 Myb-like DNA-binding domain BRCT_2 PF16589.5 CCH58869.1 - 6.9e-12 45.6 0.8 2.4e-11 43.9 0.1 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 CCH58869.1 - 7.3e-10 38.9 0.7 9.6e-06 25.7 0.1 3.1 3 0 0 3 3 3 2 Rap1 Myb domain SLIDE PF09111.10 CCH58869.1 - 0.00074 19.5 0.2 0.14 12.2 0.1 3.3 3 0 0 3 3 3 1 SLIDE Myb_DNA-bind_6 PF13921.6 CCH58869.1 - 0.01 16.1 1.9 0.6 10.4 0.0 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain DMAP1_like PF17024.5 CCH58869.1 - 0.11 12.7 0.3 0.75 9.9 0.0 2.6 2 0 0 2 2 2 0 Putative DMAP1-like HEXIM PF15313.6 CCH58869.1 - 0.49 10.6 5.1 1 9.5 3.9 2.1 1 1 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein RabGAP-TBC PF00566.18 CCH58870.1 - 5e-30 104.8 11.3 5e-30 104.8 11.3 3.0 2 1 1 3 3 3 2 Rab-GTPase-TBC domain RBFA PF02033.18 CCH58870.1 - 0.087 13.3 1.1 0.39 11.2 0.1 2.6 2 0 0 2 2 2 0 Ribosome-binding factor A NEXCaM_BD PF16644.5 CCH58870.1 - 0.22 11.8 9.0 0.74 10.1 0.1 3.6 3 0 0 3 3 3 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin PAPA-1 PF04795.12 CCH58871.1 - 8.5e-21 74.6 2.6 8.5e-21 74.6 2.6 3.0 2 1 0 2 2 2 1 PAPA-1-like conserved region MAM1 PF10434.9 CCH58871.1 - 4.6 6.8 17.1 0.017 14.7 5.1 2.2 1 1 0 2 2 2 0 Monopolin complex protein MAM1 APC_N_CC PF16689.5 CCH58872.1 - 0.27 11.3 0.3 0.27 11.3 0.3 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Neugrin PF06413.11 CCH58873.1 - 1.8e-06 28.1 0.5 1.8e-06 28.1 0.5 2.0 1 1 1 2 2 2 1 Neugrin Mod_r PF07200.13 CCH58873.1 - 0.049 13.7 0.2 0.049 13.7 0.2 2.0 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Mrx7 PF10906.8 CCH58874.1 - 3.3e-27 94.5 0.5 3.7e-27 94.3 0.5 1.0 1 0 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 CCH58875.1 - 3.3e-54 184.0 5.2 3.1e-53 180.7 5.2 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCH58875.1 - 0.00013 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCH58875.1 - 0.0065 16.5 0.0 0.019 14.9 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family KH_1 PF00013.29 CCH58876.1 - 2.5e-06 27.2 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 KH domain FAD_SOX PF18371.1 CCH58876.1 - 0.049 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase KH_2 PF07650.17 CCH58876.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 KH domain SLS PF14611.6 CCH58876.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator HSP70 PF00012.20 CCH58877.1 - 2.6e-229 762.4 9.3 2.9e-229 762.2 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH58877.1 - 4.4e-16 58.6 0.4 1.7e-14 53.4 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCH58877.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCH58877.1 - 0.32 11.4 8.6 2.8 8.4 0.0 3.8 3 3 0 3 3 3 0 Cell division protein FtsA Hom_end_hint PF05203.16 CCH58878.1 - 2.8e-45 155.0 0.0 3.4e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 CCH58878.1 - 1.6e-43 147.3 0.0 1e-36 125.5 0.0 2.4 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.6 CCH58878.1 - 1.9e-10 40.9 0.0 5.2e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF1794 PF08768.11 CCH58878.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) ArfGap PF01412.18 CCH58879.1 - 5e-33 113.6 1.1 5e-33 113.6 1.1 3.8 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.6 CCH58880.1 - 3.5e-40 138.0 0.0 4.8e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CCH58880.1 - 3e-33 114.9 0.0 3.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCH58880.1 - 0.00027 20.9 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 CCH58880.1 - 0.031 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.10 CCH58880.1 - 0.22 10.8 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) SMK-1 PF04802.15 CCH58881.1 - 2.9e-44 151.2 22.5 3.8e-24 85.6 6.0 4.7 4 0 0 4 4 4 3 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 CCH58881.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 WH1 domain Ras PF00071.22 CCH58882.1 - 5.2e-50 169.2 0.0 7.5e-50 168.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH58882.1 - 3.9e-17 62.6 0.0 9.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH58882.1 - 4.3e-08 32.8 0.1 5.7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCH58882.1 - 1.3e-05 24.9 0.0 3.2e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Menin PF05053.13 CCH58882.1 - 1 7.6 15.7 1.7 6.9 15.7 1.2 1 0 0 1 1 1 0 Menin Gly_transf_sug PF04488.15 CCH58883.1 - 3.4e-11 43.6 0.5 8.5e-11 42.4 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FlaC_arch PF05377.11 CCH58884.1 - 5.4 7.5 10.2 7.2 7.1 0.2 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PIR PF00399.19 CCH58885.1 - 6.8e-26 89.2 48.4 1.2e-07 31.1 2.8 6.0 5 0 0 5 5 5 4 Yeast PIR protein repeat Macoilin PF09726.9 CCH58885.1 - 0.1 11.1 7.8 0.13 10.8 7.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CCH58885.1 - 0.24 10.2 6.9 0.38 9.5 6.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 CCH58885.1 - 3.2 7.7 18.2 4 7.3 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 CCH58886.1 - 2.2e-17 63.1 0.0 6.8e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CCH58886.1 - 5.2e-10 39.5 0.0 7.4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CCH58886.1 - 5.1e-09 36.0 0.0 1.4e-08 34.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CCH58886.1 - 0.0013 18.2 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCH58886.1 - 0.0024 17.3 0.0 0.0035 16.8 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CCH58887.1 - 2.2e-09 37.1 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short PF00106.25 CCH58888.1 - 4.3e-16 59.0 0.0 1.8e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH58888.1 - 2.9e-09 36.9 0.0 5.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH58888.1 - 2.5e-06 27.5 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCH58888.1 - 0.0012 18.4 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCH58888.1 - 0.064 12.6 0.0 0.094 12.1 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase S-AdoMet_synt_C PF02773.16 CCH58889.1 - 5e-64 214.4 0.0 9.6e-64 213.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 CCH58889.1 - 3.7e-45 152.6 1.4 3.9e-45 152.6 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CCH58889.1 - 5.7e-45 152.5 0.0 1.1e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CCH58889.1 - 0.032 13.0 0.1 0.13 11.1 0.1 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PBP PF01161.20 CCH58890.1 - 2.1e-18 66.9 0.0 2.6e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PSP1 PF04468.12 CCH58891.1 - 1.7e-37 127.5 3.1 1.7e-37 127.5 3.1 2.0 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DHHC PF01529.20 CCH58892.1 - 1.7e-28 99.3 13.8 1.7e-28 99.3 13.8 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pkinase PF00069.25 CCH58893.1 - 7.9e-73 245.1 0.1 7.9e-73 245.1 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58893.1 - 5e-40 137.4 1.6 9.2e-40 136.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 CCH58893.1 - 1.3e-25 89.3 0.1 3.3e-13 49.6 0.0 3.2 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CCH58893.1 - 2.4e-09 36.9 0.0 2.2e-07 30.5 0.0 2.4 1 1 0 2 2 2 1 Kinase-like MH2 PF03166.14 CCH58893.1 - 0.0059 16.9 2.9 0.025 14.8 2.9 2.1 1 0 0 1 1 1 1 MH2 domain TFIIA PF03153.13 CCH58893.1 - 0.089 12.8 18.0 0.17 11.8 18.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CCH58893.1 - 0.13 10.9 3.1 0.23 10.1 3.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SH3_3 PF08239.11 CCH58893.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Met_synt_B12 PF02965.17 CCH58893.1 - 1.2 8.6 6.2 3.7 6.9 0.0 2.6 3 0 0 3 3 3 0 Vitamin B12 dependent methionine synthase, activation domain Presenilin PF01080.17 CCH58893.1 - 2.9 6.6 12.3 4.5 5.9 12.3 1.2 1 0 0 1 1 1 0 Presenilin SAP PF02037.27 CCH58894.1 - 1.7e-06 27.6 0.7 3.2e-06 26.7 0.7 1.5 1 0 0 1 1 1 1 SAP domain MMM1 PF10296.9 CCH58895.1 - 1.9e-08 33.7 0.8 6.6e-08 32.0 0.8 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PX PF00787.24 CCH58896.1 - 2.9e-22 78.8 0.1 7.5e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 PX domain TAF4 PF05236.14 CCH58897.1 - 9.2e-63 212.6 1.5 9.2e-63 212.6 1.5 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 CCH58897.1 - 0.00091 19.0 0.5 0.00091 19.0 0.5 1.8 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.14 CCH58897.1 - 0.02 14.9 3.0 0.034 14.1 3.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PLA2_B PF01735.18 CCH58898.1 - 7.8e-214 710.6 3.1 7.8e-214 710.6 3.1 1.8 2 1 0 2 2 2 1 Lysophospholipase catalytic domain IBR PF01485.21 CCH58898.1 - 0.1 12.8 0.8 0.2 11.9 0.8 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PLA2_B PF01735.18 CCH58899.1 - 3.1e-223 741.6 5.8 3.8e-223 741.3 5.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCH58899.1 - 0.024 14.8 1.2 0.044 14.0 1.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain IL3 PF02059.15 CCH58899.1 - 0.11 12.5 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Interleukin-3 zf-RING_2 PF13639.6 CCH58900.1 - 3.4e-10 40.1 6.2 6.7e-10 39.2 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CCH58900.1 - 1.3e-09 38.1 7.0 2.3e-09 37.4 7.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CCH58900.1 - 1.4e-07 31.3 4.1 2.6e-07 30.5 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCH58900.1 - 2.4e-07 30.5 7.5 5.6e-07 29.3 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH58900.1 - 2.8e-07 30.4 2.6 5.2e-07 29.6 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCH58900.1 - 3.3e-07 30.1 4.6 5.8e-07 29.3 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH58900.1 - 3.3e-05 23.7 4.1 6.9e-05 22.6 4.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCH58900.1 - 0.00015 21.6 10.2 0.0012 18.7 10.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCH58900.1 - 0.00034 20.2 0.4 0.00072 19.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CCH58900.1 - 0.00088 19.3 4.4 0.002 18.2 4.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 CCH58900.1 - 0.0074 16.5 0.4 0.022 14.9 0.4 1.8 1 0 0 1 1 1 1 Zinc-ribbon like family DUF4041 PF13250.6 CCH58900.1 - 0.02 14.7 1.3 8.3 6.4 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) zf-RING_11 PF17123.5 CCH58900.1 - 0.03 14.1 3.3 0.21 11.3 3.3 2.2 1 1 0 1 1 1 0 RING-like zinc finger NPV_P10 PF05531.12 CCH58900.1 - 0.031 14.7 0.9 0.031 14.7 0.9 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein zf-UDP PF14569.6 CCH58900.1 - 0.036 14.2 0.5 0.075 13.2 0.5 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.14 CCH58900.1 - 0.095 12.4 2.1 0.36 10.5 2.1 2.0 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 CCH58900.1 - 0.12 12.6 5.9 0.45 10.7 5.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CCH58900.1 - 0.13 12.6 2.0 0.24 11.7 2.0 1.4 1 0 0 1 1 1 0 RING-like domain DUF4349 PF14257.6 CCH58900.1 - 0.19 11.1 0.2 2.3 7.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4140 PF13600.6 CCH58900.1 - 0.21 12.1 0.2 0.39 11.2 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EMP24_GP25L PF01105.24 CCH58900.1 - 1 9.3 4.5 0.3 11.0 0.7 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RINGv PF12906.7 CCH58900.1 - 2.2 8.5 6.0 6.5 7.0 6.0 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CCH58900.1 - 2.6 8.3 7.1 8.5 6.6 5.1 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CCH58900.1 - 2.7 7.9 6.3 10 6.0 6.2 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RNA_pol_I_TF PF04090.12 CCH58901.1 - 1.2e-50 171.8 9.6 3.1e-50 170.4 9.6 1.7 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor DUF2203 PF09969.9 CCH58901.1 - 0.32 11.7 2.5 5.8 7.7 0.4 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 CCH58901.1 - 1.5 9.2 7.8 1.4 9.2 2.7 2.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) KxDL PF10241.9 CCH58901.1 - 2.2 8.6 12.2 3.6 7.9 0.4 3.7 3 0 0 3 3 3 0 Uncharacterized conserved protein Cpn60_TCP1 PF00118.24 CCH58902.1 - 8.5e-84 281.9 7.5 1.8e-83 280.8 7.5 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rubella_E2 PF05749.11 CCH58902.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Spot_14 PF07084.12 CCH58903.1 - 0.033 14.3 0.1 0.057 13.6 0.1 1.3 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 RRM_1 PF00076.22 CCH58904.1 - 1.5e-17 63.1 0.3 1.8e-16 59.7 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cdc13_OB2 PF18691.1 CCH58905.1 - 0.0063 16.6 0.0 0.087 12.9 0.0 2.6 2 1 0 2 2 2 1 Cell division control protein 13, OB2 domain POT1 PF02765.17 CCH58905.1 - 0.032 14.0 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 DUF3915 PF13054.6 CCH58905.1 - 2.9 7.9 7.3 7.8 6.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Chitin_synth_1 PF01644.17 CCH58907.1 - 2.8e-70 235.5 0.2 2.8e-70 235.5 0.2 2.0 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 CCH58907.1 - 1.1e-23 83.0 0.1 2.9e-23 81.6 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CCH58907.1 - 2.9e-19 69.1 11.4 2.4e-14 52.9 0.1 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CCH58907.1 - 4.6e-09 36.5 0.3 4.6e-09 36.5 0.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 RTC4 PF14474.6 CCH58907.1 - 0.017 15.3 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 RTC4-like domain DUF3488 PF11992.8 CCH58907.1 - 0.64 8.9 10.5 1.3 7.9 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Tyr_Deacylase PF02580.16 CCH58908.1 - 1.9e-49 167.9 0.1 2.1e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2147 PF09917.9 CCH58908.1 - 0.028 15.0 0.1 1.2 9.9 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) GATase_4 PF13230.6 CCH58909.1 - 7.5e-15 54.6 0.0 1.9e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CCH58909.1 - 2.6e-09 37.4 0.0 4.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain MARVEL PF01284.23 CCH58910.1 - 1.1e-19 70.8 8.5 1.5e-19 70.4 8.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Mfp-3 PF04202.13 CCH58910.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Foot protein 3 DUF3589 PF12141.8 CCH58911.1 - 2.5e-75 253.9 15.8 8.4e-50 169.8 0.0 2.6 2 1 1 3 3 3 2 Beta-mannosyltransferases DUF3589 PF12141.8 CCH58912.1 - 1.6e-87 294.2 8.8 5e-57 193.6 0.5 2.2 1 1 1 2 2 2 2 Beta-mannosyltransferases DUF1776 PF08643.10 CCH58912.1 - 0.00048 19.6 3.4 0.27 10.6 3.5 2.3 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) DUF3589 PF12141.8 CCH58913.1 - 7.6e-81 272.1 11.6 8.6e-54 182.9 0.0 2.4 1 1 1 2 2 2 2 Beta-mannosyltransferases DUF1700 PF08006.11 CCH58914.1 - 0.15 11.5 7.8 0.93 9.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF1700 PF08006.11 CCH58915.1 - 0.016 14.7 0.9 0.016 14.7 0.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) Clc-like PF07062.12 CCH58915.1 - 0.016 14.6 8.3 0.021 14.3 0.6 2.1 2 0 0 2 2 2 0 Clc-like zf-LITAF-like PF10601.9 CCH58915.1 - 0.076 13.3 0.9 0.076 13.3 0.9 3.5 2 2 1 3 3 3 0 LITAF-like zinc ribbon domain DUF2070 PF09843.9 CCH58915.1 - 4.5 5.4 9.7 0.74 8.0 4.7 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Arm PF00514.23 CCH58916.1 - 2.6e-85 278.1 17.5 8.1e-12 44.7 0.0 8.5 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCH58916.1 - 7.1e-26 90.5 9.6 1.7e-25 89.2 9.6 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 CCH58916.1 - 3.7e-20 71.2 4.3 8e-20 70.2 4.3 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 CCH58916.1 - 5.5e-19 68.3 0.4 2.2e-05 24.8 0.0 6.4 2 1 5 7 7 7 6 HEAT-like repeat HEAT_2 PF13646.6 CCH58916.1 - 4.1e-11 43.1 0.9 0.0015 18.8 0.0 5.1 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.22 CCH58916.1 - 4.5e-10 38.9 0.0 2.7 8.5 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat Arm_2 PF04826.13 CCH58916.1 - 1.9e-06 27.6 0.9 0.014 14.9 0.0 4.1 2 2 2 5 5 5 2 Armadillo-like RICTOR_V PF14668.6 CCH58916.1 - 1.1e-05 25.6 2.4 0.13 12.6 0.0 4.8 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 CCH58916.1 - 0.00055 18.6 0.2 0.0032 16.1 0.2 2.4 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 CCH58916.1 - 0.00084 19.4 0.1 8 6.6 0.0 4.1 3 2 0 3 3 3 2 V-ATPase subunit H NopRA1 PF16201.5 CCH58916.1 - 0.0011 18.6 0.0 1.1 8.9 0.0 4.3 1 1 1 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 CCH58916.1 - 0.0039 17.2 0.3 1.8 8.6 0.0 4.0 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain JAB PF01398.21 CCH58918.1 - 2.2e-29 101.8 0.2 4.5e-29 100.8 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CCH58918.1 - 0.0005 19.8 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CCH58918.1 - 0.019 15.0 0.0 0.041 13.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Syntaxin-6_N PF09177.11 CCH58918.1 - 0.26 11.9 4.0 4.1 8.0 0.6 2.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal ELFV_dehydrog PF00208.21 CCH58919.1 - 1.8e-63 214.5 0.0 3.6e-63 213.5 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CCH58919.1 - 1.6e-19 69.0 0.4 1.3e-12 46.2 0.0 2.3 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CCH58919.1 - 0.0024 17.7 0.0 0.0074 16.2 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.25 CCH58920.1 - 1.4e-43 149.2 0.0 2.5e-43 148.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH58920.1 - 1.5e-19 70.3 0.0 2.3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH58920.1 - 0.0098 15.2 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.22 CCH58921.1 - 4.2e-06 26.5 0.0 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH58921.1 - 0.088 12.9 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif tRNA_synt_1c_R2 PF04557.15 CCH58921.1 - 4.7 8.2 9.6 4.6 8.2 1.2 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ras PF00071.22 CCH58922.1 - 5.9e-42 143.0 0.0 9.8e-40 135.8 0.0 2.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CCH58922.1 - 2e-17 63.5 0.0 2.9e-08 33.9 0.0 3.1 1 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH58922.1 - 0.0001 21.8 0.0 0.47 9.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DGF-1_C PF11040.8 CCH58922.1 - 0.2 11.6 5.8 1.2 9.1 4.0 2.6 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Macoilin PF09726.9 CCH58922.1 - 4.3 5.8 15.0 5.3 5.5 15.0 1.1 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 CCH58924.1 - 2.9e-25 87.9 0.2 4.7e-17 61.6 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH58924.1 - 0.00037 20.5 0.0 0.99 9.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCH58924.1 - 0.00054 19.9 0.1 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif AMPK1_CBM PF16561.5 CCH58925.1 - 1.2e-14 54.3 0.5 4.5e-14 52.4 0.5 2.1 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF2151 PF10221.9 CCH58925.1 - 7.4 5.0 31.2 4 5.9 19.1 2.2 2 0 0 2 2 2 0 Cell cycle and development regulator ANAPC1 PF12859.7 CCH58926.1 - 1.9e-06 28.4 0.1 1.9e-06 28.4 0.1 3.9 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CCH58926.1 - 0.0042 17.5 6.6 0.98 10.0 0.0 4.2 3 0 0 3 3 3 2 Proteasome/cyclosome repeat Sugar_tr PF00083.24 CCH58927.1 - 1.2e-162 541.9 34.3 1.5e-162 541.6 34.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH58927.1 - 2.7e-34 118.7 32.1 9.8e-33 113.5 24.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH58927.1 - 0.00012 20.7 1.0 0.00029 19.4 1.0 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PS_Dcarbxylase PF02666.15 CCH58928.1 - 9.9e-71 237.4 0.0 1.5e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase dCMP_cyt_deam_1 PF00383.23 CCH58929.1 - 4.3e-27 94.0 1.0 6.6e-27 93.3 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCH58929.1 - 1.1e-14 54.3 0.1 2e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CCH58929.1 - 0.14 12.3 0.6 0.31 11.2 0.2 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 FAA_hydrolase PF01557.18 CCH58930.1 - 1.9e-47 161.8 0.0 2.4e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Hydantoinase_B PF02538.14 CCH58930.1 - 0.15 10.4 0.0 0.37 9.2 0.0 1.6 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase DNA_RNApol_7kD PF03604.13 CCH58931.1 - 9.3e-17 60.4 1.5 1.2e-16 60.0 1.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 CCH58931.1 - 0.004 17.2 0.5 0.0056 16.7 0.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2197 PF09963.9 CCH58931.1 - 0.0053 17.0 1.1 0.72 10.2 0.1 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) zf_UBZ PF18439.1 CCH58931.1 - 0.0057 16.2 1.6 1.5 8.5 0.1 2.2 1 1 1 2 2 2 2 Ubiquitin-Binding Zinc Finger HypA PF01155.19 CCH58931.1 - 0.0092 16.0 0.2 0.0092 16.0 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CCH58931.1 - 0.025 14.5 0.7 0.032 14.2 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbons MCM_OB PF17207.3 CCH58931.1 - 0.035 14.0 0.3 0.038 13.8 0.3 1.1 1 0 0 1 1 1 0 MCM OB domain zinc_ribbon_10 PF10058.9 CCH58931.1 - 0.035 13.8 0.3 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein TFIIS_C PF01096.18 CCH58931.1 - 0.048 13.5 3.7 3.8 7.5 0.1 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) DUF4428 PF14471.6 CCH58931.1 - 0.077 12.9 2.0 1 9.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) FYDLN_acid PF09538.10 CCH58931.1 - 0.13 12.9 0.6 0.15 12.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn_ribbon_SprT PF17283.2 CCH58931.1 - 0.14 12.1 2.2 0.19 11.7 1.3 1.7 1 1 2 3 3 3 0 SprT-like zinc ribbon domain Ribosomal_L44 PF00935.19 CCH58931.1 - 0.18 12.3 5.1 3.2 8.3 0.3 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Zn-ribbon_8 PF09723.10 CCH58931.1 - 0.18 11.9 2.9 0.66 10.1 2.9 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 CCH58931.1 - 0.2 12.2 2.6 3.7 8.2 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Rubredoxin_2 PF18073.1 CCH58931.1 - 0.53 10.1 2.7 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain EcsC PF12787.7 CCH58932.1 - 4.9 6.8 6.6 0.67 9.6 1.4 2.4 2 0 0 2 2 2 0 EcsC protein family YpjP PF14005.6 CCH58932.1 - 8.4 6.4 22.4 0.077 13.0 9.9 3.4 2 1 0 3 3 3 0 YpjP-like protein ydhR PF08803.11 CCH58933.1 - 0.0013 18.6 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 2 Putative mono-oxygenase ydhR MCR_D PF02505.14 CCH58934.1 - 0.0013 18.6 0.5 0.67 9.8 0.2 2.3 1 1 1 2 2 2 2 Methyl-coenzyme M reductase operon protein D YfhO PF09586.10 CCH58934.1 - 1.9 6.6 4.4 2.7 6.1 4.4 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Chs7 PF12271.8 CCH58935.1 - 2.2e-110 368.5 21.2 2.6e-110 368.3 21.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2583 PF10762.9 CCH58935.1 - 2.8 8.4 7.7 2 8.9 1.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Ribosomal_L44 PF00935.19 CCH58936.1 - 5.2e-36 123.0 11.6 7.9e-36 122.4 11.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Far-17a_AIG1 PF04750.14 CCH58937.1 - 9.9e-16 57.6 2.2 1.3e-15 57.3 2.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Ammonium_transp PF00909.21 CCH58939.1 - 2.1e-126 421.9 26.9 2.4e-126 421.6 26.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Prefoldin_2 PF01920.20 CCH58941.1 - 1.6e-18 66.6 12.6 1.9e-18 66.4 12.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit PspA_IM30 PF04012.12 CCH58941.1 - 0.00077 19.1 1.7 0.001 18.7 1.7 1.2 1 0 0 1 1 1 1 PspA/IM30 family GCR PF02155.15 CCH58941.1 - 0.011 14.8 0.4 0.012 14.7 0.4 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor Baculo_PEP_C PF04513.12 CCH58941.1 - 0.025 14.6 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 CCH58941.1 - 0.032 14.6 0.4 0.032 14.6 0.4 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSBP1 PF06825.12 CCH58941.1 - 0.093 12.6 5.0 0.13 12.2 0.8 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 CCH58941.1 - 0.1 12.9 0.3 0.1 12.9 0.3 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Enkurin PF13864.6 CCH58941.1 - 0.77 10.2 9.6 3 8.3 0.5 2.6 2 1 1 3 3 3 0 Calmodulin-binding XhlA PF10779.9 CCH58941.1 - 1.8 8.9 7.2 0.14 12.4 0.9 2.0 2 0 0 2 2 2 0 Haemolysin XhlA Fib_alpha PF08702.10 CCH58941.1 - 2 8.6 7.5 3 8.0 4.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CCH58941.1 - 4.4 7.2 10.9 0.73 9.7 0.5 2.2 1 1 0 2 2 2 0 Septum formation initiator Aminotran_1_2 PF00155.21 CCH58942.1 - 4.8e-10 39.2 0.0 8.2e-10 38.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II SDP_N PF12278.8 CCH58943.1 - 0.48 10.5 10.9 0.065 13.4 6.9 1.5 2 0 0 2 2 2 0 Sex determination protein N terminal Presenilin PF01080.17 CCH58943.1 - 2.2 7.0 5.8 2.4 6.8 5.8 1.2 1 0 0 1 1 1 0 Presenilin WLM PF08325.10 CCH58944.1 - 3.5e-53 180.5 0.9 4.3e-53 180.2 0.9 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 CCH58944.1 - 0.011 15.8 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Peptidase_M1 PF01433.20 CCH58944.1 - 0.17 11.4 0.1 0.27 10.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M1 domain INSIG PF07281.12 CCH58945.1 - 8.1e-19 68.1 10.5 1.1e-16 61.1 10.5 2.7 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Endosulfine PF04667.17 CCH58946.1 - 2e-32 111.1 0.3 2.6e-32 110.8 0.3 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_M14 PF00246.24 CCH58947.1 - 2.8e-70 237.4 0.0 3.4e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Actin PF00022.19 CCH58950.1 - 2.7e-111 372.1 0.0 3e-110 368.6 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCH58950.1 - 0.059 12.2 0.0 7.9 5.2 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein UPRTase PF14681.6 CCH58951.1 - 1.8e-76 256.2 0.0 2.3e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CCH58951.1 - 0.0081 15.7 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 CCH58951.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) LSM PF01423.22 CCH58952.1 - 1.1e-20 73.1 0.2 1.5e-20 72.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain Presenilin PF01080.17 CCH58952.1 - 0.31 9.8 0.6 0.26 10.0 0.6 1.1 1 0 0 1 1 1 0 Presenilin CAP_GLY PF01302.25 CCH58953.1 - 3.8e-19 68.5 0.4 5.3e-19 68.0 0.4 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CCH58953.1 - 9.4e-08 32.4 0.1 9.4e-08 32.4 0.1 1.9 2 1 0 2 2 2 1 Ubiquitin-like domain L31 PF09784.9 CCH58953.1 - 0.051 14.0 0.2 0.086 13.3 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Choline_kinase PF01633.20 CCH58953.1 - 0.54 9.8 7.8 0.34 10.5 1.6 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase C2 PF00168.30 CCH58954.1 - 8.5e-08 32.4 0.0 1.6e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain CAP_N PF01213.19 CCH58956.1 - 5.2e-106 354.7 12.2 5.2e-106 354.7 12.2 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CCH58956.1 - 1.8e-56 190.1 1.1 3.4e-56 189.2 1.1 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CCH58956.1 - 0.022 14.5 1.3 0.051 13.3 1.3 1.7 1 0 0 1 1 1 0 Tubulin binding cofactor C Caskin-Pro-rich PF16907.5 CCH58956.1 - 0.042 14.4 1.5 0.042 14.4 1.5 2.5 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Nmad3 PF18754.1 CCH58956.1 - 0.065 12.8 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Nucleotide modification associated domain 3 Caprin-1_dimer PF18293.1 CCH58956.1 - 0.14 12.7 0.3 2.5 8.6 0.0 2.6 2 1 1 3 3 3 0 Caprin-1 dimerization domain S4 PF01479.25 CCH58957.1 - 4.2e-16 58.4 0.0 8.6e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CCH58957.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 S4 domain COX6C PF02937.15 CCH58957.1 - 0.12 12.5 0.7 0.52 10.5 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc GN3L_Grn1 PF08701.11 CCH58957.1 - 0.14 12.2 3.1 0.43 10.7 3.1 1.8 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Eaf7 PF07904.13 CCH58958.1 - 5.7e-36 123.1 0.3 5.7e-36 123.1 0.3 4.2 3 2 0 3 3 3 1 Chromatin modification-related protein EAF7 Orf78 PF06024.12 CCH58959.1 - 1.4 9.2 12.0 29 5.0 12.0 2.2 1 1 0 1 1 1 0 Orf78 (ac78) SMYLE_N PF18615.1 CCH58959.1 - 2.7 7.5 9.3 2.8 7.4 9.3 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain FKBP_C PF00254.28 CCH58960.1 - 3.1e-33 114.0 0.0 3.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_racemase PF05544.11 CCH58960.1 - 0.21 10.6 0.0 0.24 10.4 0.0 1.0 1 0 0 1 1 1 0 Proline racemase CDP-OH_P_transf PF01066.21 CCH58962.1 - 3.2e-14 53.5 0.3 3.2e-14 53.5 0.3 3.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FeS_assembly_P PF01883.19 CCH58963.1 - 1.2e-06 28.6 0.0 2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein DSPc PF00782.20 CCH58964.1 - 9.5e-09 35.2 1.3 2.9e-08 33.6 1.3 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCH58964.1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CCH58964.1 - 0.032 14.5 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain BCAS2 PF05700.11 CCH58964.1 - 0.046 13.4 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Y_phosphatase3 PF13350.6 CCH58964.1 - 0.071 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CCH58964.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Gar1 PF04410.14 CCH58965.1 - 1e-41 142.2 2.7 1e-41 142.2 2.7 2.8 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region SOBP PF15279.6 CCH58965.1 - 0.54 10.8 43.0 0.23 12.0 26.9 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Ribosomal_L35p PF01632.19 CCH58966.1 - 6e-08 33.1 5.6 3.3e-07 30.7 5.6 1.8 1 1 0 1 1 1 1 Ribosomal protein L35 Pet191_N PF10203.9 CCH58967.1 - 5.3e-05 23.4 1.0 7.7e-05 22.9 1.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CCH58967.1 - 8.3e-05 22.6 2.1 0.00013 22.0 2.1 1.3 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CCH58967.1 - 0.025 15.0 4.4 0.16 12.4 3.5 2.0 1 1 1 2 2 2 0 GCK domain RBDV_coat PF06593.11 CCH58967.1 - 0.11 11.9 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein Malate_synthase PF01274.22 CCH58968.1 - 1.2e-213 710.2 0.0 1.4e-213 710.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FHA PF00498.26 CCH58969.1 - 2.1e-15 56.8 1.5 4.2e-15 55.8 0.0 2.4 3 0 0 3 3 2 1 FHA domain zf-RING_11 PF17123.5 CCH58969.1 - 4.8e-11 42.2 11.0 8.3e-11 41.4 11.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CCH58969.1 - 5.4e-07 29.8 11.4 9.1e-07 29.1 11.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CCH58969.1 - 0.0011 19.2 7.6 0.0028 17.9 7.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCH58969.1 - 0.0012 18.8 5.0 0.0028 17.7 5.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Yop-YscD_cpl PF16697.5 CCH58969.1 - 0.0029 17.9 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 CCH58969.1 - 0.0047 16.8 11.1 0.0088 15.9 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH58969.1 - 0.0059 16.5 8.9 0.0098 15.8 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCH58969.1 - 0.017 15.0 11.0 0.028 14.2 11.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.14 CCH58969.1 - 0.12 11.9 0.2 0.31 10.6 0.2 1.7 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-RING_UBOX PF13445.6 CCH58969.1 - 0.36 10.9 10.2 0.72 9.9 10.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger FYDLN_acid PF09538.10 CCH58969.1 - 3.9 8.2 16.9 6.9 7.4 3.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF2417 PF10329.9 CCH58970.1 - 4.3e-66 222.7 15.7 6.2e-66 222.2 15.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 CCH58970.1 - 7.7e-17 61.8 0.1 1.6e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCH58970.1 - 6.9e-05 23.5 0.0 9.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CCH58970.1 - 0.012 15.3 0.1 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCH58970.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 CCH58970.1 - 0.14 12.3 0.1 0.37 10.9 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain POB3_N PF17292.2 CCH58970.1 - 0.16 12.4 1.6 0.96 9.9 0.1 2.5 2 1 0 2 2 2 0 POB3-like N-terminal PH domain Orf78 PF06024.12 CCH58970.1 - 1.1 9.6 10.4 4.5 7.6 1.4 3.6 4 0 0 4 4 4 0 Orf78 (ac78) zf-H2C2_2 PF13465.6 CCH58971.1 - 1e-19 70.0 31.3 1.8e-07 31.3 1.9 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 CCH58971.1 - 1.3e-19 69.5 32.4 1.4e-05 25.3 1.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH58971.1 - 5.2e-11 42.4 27.8 0.00055 20.5 0.9 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 CCH58971.1 - 0.00064 20.0 20.8 0.0082 16.5 0.7 4.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CCH58971.1 - 0.0078 16.5 8.1 0.037 14.3 0.8 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CCH58971.1 - 0.032 14.5 0.6 0.032 14.5 0.6 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CCH58971.1 - 0.18 11.9 9.2 0.14 12.3 1.8 3.2 3 0 0 3 3 3 0 Zinc ribbon domain PyrI_C PF02748.15 CCH58971.1 - 0.38 10.7 5.4 14 5.6 0.1 3.3 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 CCH58971.1 - 0.86 10.4 6.9 0.7 10.7 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon family zf-BED PF02892.15 CCH58971.1 - 0.95 9.5 21.8 1.4 9.0 0.6 3.9 3 1 1 4 4 4 0 BED zinc finger C1_4 PF07975.12 CCH58971.1 - 1.7 8.9 6.2 2.8 8.2 1.1 2.8 2 1 0 2 2 2 0 TFIIH C1-like domain Prok-RING_1 PF14446.6 CCH58971.1 - 2 8.4 4.5 36 4.4 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-LYAR PF08790.11 CCH58971.1 - 6.2 6.8 7.2 30 4.6 0.1 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger RNA_pol_L_2 PF13656.6 CCH58972.1 - 6.1e-33 112.4 0.0 7e-33 112.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCH58972.1 - 6e-15 54.4 0.0 7.8e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Maf PF02545.14 CCH58973.1 - 3.1e-36 124.7 0.0 3.5e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Cyt-b5 PF00173.28 CCH58974.1 - 1.6e-23 82.6 0.0 2.1e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFIIIC_sub6 PF10419.9 CCH58975.1 - 2.2e-17 62.7 0.1 3.9e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_Phos_1 PF00300.22 CCH58975.1 - 1.8e-16 60.5 0.0 4.5e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YEATS PF03366.16 CCH58976.1 - 9.1e-33 112.1 1.0 1.5e-32 111.4 1.0 1.4 1 0 0 1 1 1 1 YEATS family DUF382 PF04037.13 CCH58976.1 - 0.13 12.4 1.6 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF382) ATP_bind_2 PF03668.15 CCH58976.1 - 0.14 11.4 1.4 1.9 7.7 0.4 2.0 1 1 1 2 2 2 0 P-loop ATPase protein family HCO3_cotransp PF00955.21 CCH58976.1 - 0.29 9.9 0.2 0.39 9.5 0.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family Syja_N PF02383.18 CCH58977.1 - 1.1e-69 235.2 0.7 1.1e-69 235.2 0.7 2.1 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 CCH58977.1 - 3.7e-13 49.5 0.0 7.2e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HMGL-like PF00682.19 CCH58978.1 - 4.1e-87 292.1 0.0 5.7e-87 291.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CCH58978.1 - 2.9e-22 79.0 0.0 5.7e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Kinesin_assoc PF16183.5 CCH58978.1 - 0.12 12.5 0.2 0.3 11.2 0.1 1.7 2 0 0 2 2 2 0 Kinesin-associated Ribosomal_S21 PF01165.20 CCH58978.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S21 DNA_pol_B PF00136.21 CCH58980.1 - 4.6e-120 401.4 7.1 8.1e-120 400.6 7.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CCH58980.1 - 2.8e-63 213.0 5.7 2.8e-63 213.0 5.7 2.2 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CCH58980.1 - 6.5e-42 143.9 0.0 6.5e-42 143.9 0.0 2.7 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CCH58980.1 - 7.3e-19 67.6 8.3 2.8e-18 65.8 8.3 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal zinc_ribbon_4 PF13717.6 CCH58980.1 - 0.15 12.0 1.0 20 5.2 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF4519 PF15012.6 CCH58980.1 - 0.17 12.1 0.4 0.75 10.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Zn-ribbon_8 PF09723.10 CCH58980.1 - 0.19 11.9 1.2 3.3 7.9 0.2 2.7 2 0 0 2 2 2 0 Zinc ribbon domain ApoO PF09769.9 CCH58981.1 - 0.0076 16.2 0.4 0.15 12.0 0.1 2.3 2 0 0 2 2 2 2 Apolipoprotein O Y_phosphatase2 PF03162.13 CCH58982.1 - 5.9e-56 188.6 0.0 7.6e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCH58982.1 - 2.7e-05 24.2 0.0 4.8e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family DAD PF02109.16 CCH58983.1 - 6.6e-37 126.1 6.5 9e-37 125.7 6.5 1.2 1 0 0 1 1 1 1 DAD family DUF2207 PF09972.9 CCH58983.1 - 0.00063 18.6 0.3 0.00075 18.4 0.3 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PalH PF08733.10 CCH58983.1 - 0.003 16.6 3.7 0.0033 16.5 3.7 1.0 1 0 0 1 1 1 1 PalH/RIM21 Ras PF00071.22 CCH58984.1 - 6.5e-44 149.4 0.2 1.1e-43 148.6 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH58984.1 - 5.6e-16 58.8 0.0 2.3e-15 56.8 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH58984.1 - 7e-10 38.6 0.1 1.5e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCH58984.1 - 4.7e-05 23.4 0.0 4.7e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH58984.1 - 0.00073 19.1 0.0 0.0049 16.4 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCH58984.1 - 0.0056 16.1 0.8 0.013 14.9 0.8 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCH58984.1 - 0.0068 16.3 0.1 0.78 9.6 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase CENP-B_dimeris PF09026.10 CCH58984.1 - 0.033 14.6 6.4 0.11 12.9 6.4 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TraG-D_C PF12696.7 CCH58984.1 - 0.65 10.0 7.9 1.9 8.5 6.1 2.8 2 1 0 2 2 2 0 TraM recognition site of TraD and TraG Mito_carr PF00153.27 CCH58986.1 - 9.9e-58 192.1 4.4 3.6e-20 71.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_15 PF01793.16 CCH58987.1 - 1.4e-128 428.7 14.0 1.8e-128 428.4 14.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1179 PF06678.11 CCH58988.1 - 0.093 12.7 2.7 0.12 12.3 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1179) Popeye PF04831.13 CCH58988.1 - 0.26 11.5 1.9 0.41 10.8 1.9 1.3 1 0 0 1 1 1 0 Popeye protein conserved region Ribosomal_S7e PF01251.18 CCH58989.1 - 6.3e-81 270.5 3.3 7.4e-81 270.3 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF692 PF05114.13 CCH58989.1 - 0.019 14.1 0.0 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF692) Rib_5-P_isom_A PF06026.14 CCH58990.1 - 3.5e-56 189.5 0.0 4.4e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CCH58990.1 - 0.013 15.4 0.0 6.5 6.7 0.0 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain Arf PF00025.21 CCH58991.1 - 4.1e-72 241.3 0.6 4.7e-72 241.1 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCH58991.1 - 6.1e-16 58.7 0.1 9.7e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCH58991.1 - 1.4e-15 57.1 0.0 1.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CCH58991.1 - 4e-14 52.5 0.1 4.7e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CCH58991.1 - 5.2e-13 48.9 1.3 3.2e-08 33.1 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCH58991.1 - 3.4e-10 39.7 0.0 4.2e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH58991.1 - 1.5e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CCH58991.1 - 0.095 12.0 0.3 0.2 10.9 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AMP-binding PF00501.28 CCH58992.1 - 1.6e-37 129.1 0.0 9.6e-16 57.4 0.0 4.4 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 CCH58992.1 - 1.3e-08 35.6 0.1 1.3e-08 35.6 0.1 3.1 3 0 0 3 3 3 1 DMAP1-binding Domain TMEM210 PF15195.6 CCH58992.1 - 0.074 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 TMEM210 family Mem_trans PF03547.18 CCH58993.1 - 4.7e-30 104.3 1.8 6.6e-30 103.8 1.8 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF2183 PF09949.9 CCH58994.1 - 1.9e-28 98.7 0.1 5.1e-28 97.3 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 CCH58994.1 - 0.0078 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DFRP_C PF16543.5 CCH58995.1 - 6.9e-22 77.7 3.4 6.9e-22 77.7 3.4 3.7 3 1 1 4 4 4 2 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 CCH58995.1 - 3e-06 27.9 9.1 0.00074 20.2 3.7 3.2 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 CCH58995.1 - 3.3e-05 23.8 14.4 9.4e-05 22.3 3.6 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 CCH58995.1 - 8e-05 22.5 0.1 8e-05 22.5 0.1 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CCH58995.1 - 0.00011 21.9 7.2 0.014 15.2 0.6 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCH58995.1 - 0.072 13.6 12.2 0.64 10.6 2.8 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CCH58995.1 - 0.29 11.4 7.1 2 8.7 0.3 2.8 2 1 1 3 3 3 0 Zinc-finger containing family GSHPx PF00255.19 CCH58996.1 - 1.2e-47 159.9 0.3 1.7e-47 159.5 0.3 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CCH58996.1 - 7.2e-05 22.7 0.1 0.00014 21.8 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCH58996.1 - 0.00065 19.4 0.1 0.0014 18.3 0.1 1.7 1 1 0 1 1 1 1 Redoxin Ion_trans PF00520.31 CCH58997.1 - 4.5e-08 32.6 19.9 4.5e-08 32.6 19.9 1.9 2 0 0 2 2 2 1 Ion transport protein DivIC PF04977.15 CCH58997.1 - 0.096 12.5 1.3 0.35 10.7 1.3 2.0 1 0 0 1 1 1 0 Septum formation initiator BCDHK_Adom3 PF10436.9 CCH58998.1 - 2.7e-26 92.3 0.2 4.5e-26 91.6 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCH58998.1 - 1.9e-11 44.5 0.0 5e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCH58998.1 - 0.0008 19.3 0.0 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S18 PF01084.20 CCH58999.1 - 1.7e-16 60.2 0.1 3.8e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PhyH PF05721.13 CCH58999.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.3 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_6 PF00970.24 CCH59000.1 - 4.1e-17 62.4 0.0 1.4e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCH59000.1 - 0.0006 20.4 0.0 0.0014 19.2 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain BAR_2 PF10455.9 CCH59001.1 - 8.6e-64 215.4 16.8 1.2e-63 214.9 16.8 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCH59001.1 - 2.7e-14 53.4 10.6 3.3e-13 49.9 10.6 2.2 1 1 0 1 1 1 1 BAR domain DEAD PF00270.29 CCH59002.1 - 1.3e-48 165.1 0.0 1.6e-47 161.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59002.1 - 5.2e-21 75.1 0.0 1.7e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CCH59002.1 - 8.7e-19 67.5 3.9 8.7e-19 67.5 3.9 3.1 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Peptidase_C10 PF01640.17 CCH59002.1 - 0.077 13.3 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase C10 family DUF3449 PF11931.8 CCH59003.1 - 4.1e-28 98.4 0.0 1.8e-24 86.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.8 CCH59003.1 - 3.6e-10 39.9 2.6 0.00055 20.1 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CCH59003.1 - 0.0015 18.9 0.2 0.33 11.3 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CCH59003.1 - 0.27 11.7 6.6 2 8.9 1.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3446 PF11928.8 CCH59003.1 - 1.3 9.3 10.3 1.1 9.5 3.8 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain zf-C2H2_4 PF13894.6 CCH59003.1 - 1.6 9.7 9.4 4.1 8.5 0.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger SR-25 PF10500.9 CCH59003.1 - 3.1 7.4 6.6 1.1 8.8 3.8 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NAD_Gly3P_dh_N PF01210.23 CCH59004.1 - 4e-52 176.3 0.5 6.2e-52 175.7 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CCH59004.1 - 2.5e-41 141.3 0.1 4e-41 140.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CCH59004.1 - 0.0015 19.1 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 CCH59004.1 - 0.05 13.2 0.0 0.85 9.2 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Oxysterol_BP PF01237.18 CCH59005.1 - 9.9e-127 422.8 0.5 9.9e-127 422.8 0.5 3.0 4 0 0 4 4 4 1 Oxysterol-binding protein Ank_4 PF13637.6 CCH59005.1 - 1.3e-10 41.6 0.0 0.00043 20.8 0.1 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 CCH59005.1 - 2e-09 37.9 0.1 2e-09 37.9 0.1 2.3 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 CCH59005.1 - 7e-09 35.8 3.7 5.9e-08 32.9 0.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.6 CCH59005.1 - 9.5e-09 34.8 0.0 0.0065 16.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CCH59005.1 - 3e-08 33.7 0.0 0.0019 18.6 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CCH59005.1 - 3.3e-08 34.0 0.1 0.0018 18.8 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCH59005.1 - 2.6e-06 27.6 4.1 0.0061 16.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH_11 PF15413.6 CCH59005.1 - 0.11 12.9 6.2 2.3 8.7 6.2 3.4 1 1 0 1 1 1 0 Pleckstrin homology domain PYRIN PF02758.16 CCH59005.1 - 0.12 12.5 2.8 0.16 12.2 0.6 2.4 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain Pkinase PF00069.25 CCH59006.1 - 1.1e-75 254.4 0.1 1.1e-75 254.4 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59006.1 - 1.9e-55 188.0 0.0 3.7e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59006.1 - 3.8e-07 29.7 0.1 2.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCH59006.1 - 0.0023 16.8 0.7 0.0023 16.8 0.7 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCH59006.1 - 0.084 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_1 PF00018.28 CCH59007.1 - 4.3e-09 35.8 0.0 1.1e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH59007.1 - 0.001 18.9 0.1 0.0026 17.6 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF4228 PF14009.6 CCH59007.1 - 0.02 15.3 0.1 0.87 10.0 0.0 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4228) Pkinase PF00069.25 CCH59008.1 - 1.2e-37 129.8 0.0 8.1e-22 77.8 0.0 3.4 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59008.1 - 9.6e-14 51.3 0.0 2.3e-09 36.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CCH59008.1 - 0.0006 19.8 0.0 0.00096 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCH59008.1 - 0.051 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CCH59008.1 - 0.14 11.4 0.0 17 4.6 0.0 2.7 3 0 0 3 3 3 0 Kinase-like Steroid_dh PF02544.16 CCH59009.1 - 6e-31 107.4 11.5 1.4e-30 106.3 11.5 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DPPIV_rep PF18811.1 CCH59009.1 - 0.5 10.4 2.5 19 5.3 0.1 2.8 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) low complexity region DUF2663 PF10864.8 CCH59009.1 - 0.52 10.7 5.4 0.47 10.9 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Fibrillarin PF01269.17 CCH59010.1 - 8.9e-108 358.6 0.0 1.1e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CCH59010.1 - 6.6e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CCH59010.1 - 0.017 15.2 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CCH59010.1 - 0.076 12.6 0.0 0.24 11.0 0.0 1.8 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 CCH59010.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CYSTM PF12734.7 CCH59011.1 - 9.5e-15 54.6 8.2 1.2e-14 54.3 8.2 1.1 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Bac_rhodopsin PF01036.18 CCH59012.1 - 6e-50 169.9 17.5 7e-50 169.7 17.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1422 PF07226.11 CCH59012.1 - 0.031 14.3 1.2 0.031 14.3 1.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1422) Bac_rhodopsin PF01036.18 CCH59013.1 - 2.5e-48 164.6 17.4 2.8e-48 164.4 17.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCH59013.1 - 0.048 13.3 4.0 2.7 7.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1422 PF07226.11 CCH59013.1 - 0.48 10.5 5.1 0.22 11.5 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Bac_rhodopsin PF01036.18 CCH59014.1 - 3.5e-49 167.4 18.0 4.1e-49 167.2 18.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1422 PF07226.11 CCH59014.1 - 0.047 13.7 1.3 0.047 13.7 1.3 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1422) Bac_rhodopsin PF01036.18 CCH59015.1 - 6.1e-49 166.6 17.6 7.1e-49 166.4 17.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4792 PF16040.5 CCH59015.1 - 0.087 12.7 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) DUF4131 PF13567.6 CCH59015.1 - 0.77 9.4 7.4 9 5.9 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Bac_rhodopsin PF01036.18 CCH59016.1 - 1.7e-47 161.9 15.9 2e-47 161.6 15.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein RT_RNaseH_2 PF17919.1 CCH59017.1 - 1.8e-17 63.2 0.0 3.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH59017.1 - 1.3e-15 57.6 0.0 1.9e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF5493 PF17597.2 CCH59017.1 - 0.11 12.8 0.1 0.42 10.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5493) Ras PF00071.22 CCH59018.1 - 4.2e-57 192.3 0.4 4.2e-57 192.3 0.4 2.0 2 1 0 2 2 2 1 Ras family Roc PF08477.13 CCH59018.1 - 5.9e-21 74.9 0.0 5.9e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH59018.1 - 1.6e-08 34.2 0.1 2.5e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_33 PF13671.6 CCH59018.1 - 0.5 10.5 0.0 0.5 10.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain ING PF12998.7 CCH59019.1 - 1.2e-13 51.5 0.4 1.9e-13 50.9 0.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCH59019.1 - 0.00052 19.8 7.5 0.00084 19.2 7.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCH59019.1 - 0.07 13.4 2.1 0.15 12.4 2.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain SOG2 PF10428.9 CCH59019.1 - 0.97 8.6 23.2 1.6 7.8 23.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_transf_15 PF01793.16 CCH59020.1 - 2.7e-77 260.2 16.8 3.6e-77 259.8 16.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rib_5-P_isom_A PF06026.14 CCH59022.1 - 1.2e-56 191.0 0.0 1.5e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CCH59022.1 - 0.0014 18.6 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Mem_trans PF03547.18 CCH59023.1 - 2.3e-32 111.9 0.0 4e-32 111.1 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein TACC_C PF05010.14 CCH59023.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Rabaptin PF03528.15 CCH59023.1 - 0.2 10.3 2.2 0.31 9.7 2.2 1.2 1 0 0 1 1 1 0 Rabaptin Ras PF00071.22 CCH59024.1 - 3.7e-51 172.9 0.0 4.3e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH59024.1 - 7.8e-23 81.0 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH59024.1 - 3.7e-10 39.5 0.0 4.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CCH59024.1 - 0.0014 18.3 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CCH59024.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCH59024.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit NST1 PF13945.6 CCH59025.1 - 1.9e-08 34.6 14.6 1.9e-08 34.6 14.6 9.4 6 2 2 8 8 8 2 Salt tolerance down-regulator Ras PF00071.22 CCH59026.1 - 6.2e-60 201.5 0.1 7.6e-60 201.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH59026.1 - 4.3e-35 120.5 0.0 6.3e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH59026.1 - 4e-18 65.5 0.0 4.7e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH59026.1 - 2.4e-07 30.4 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH59026.1 - 6.6e-06 26.2 0.0 1.3e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH59026.1 - 3.8e-05 23.7 0.1 0.072 13.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CCH59026.1 - 7.9e-05 22.3 0.0 9.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CCH59026.1 - 0.15 12.4 0.1 0.27 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain PP2C PF00481.21 CCH59027.1 - 5.5e-45 154.0 0.0 9e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF846 PF05832.12 CCH59028.1 - 4.6e-46 156.3 7.5 5.7e-46 156.0 7.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FA_desaturase PF00487.24 CCH59028.1 - 6 6.6 9.2 0.65 9.8 4.5 1.7 1 1 1 2 2 2 0 Fatty acid desaturase Methyltransf_8 PF05148.15 CCH59029.1 - 7.4e-66 222.1 3.8 5.1e-64 216.1 0.6 2.8 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CCH59029.1 - 1.3e-08 35.3 0.0 6.6e-08 33.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH59029.1 - 1.6e-05 25.5 0.1 9.7e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH59029.1 - 0.0029 17.4 0.2 0.0029 17.4 0.2 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ndc1_Nup PF09531.10 CCH59029.1 - 0.54 8.9 7.4 0.64 8.6 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CCH59029.1 - 1.3 7.7 13.8 2 7.1 13.8 1.2 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 CCH59029.1 - 4.3 7.3 20.1 3.8 7.5 14.7 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Clathrin PF00637.20 CCH59030.1 - 1.7e-26 92.8 2.6 2.2e-23 82.7 0.1 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS WD40 PF00400.32 CCH59030.1 - 0.0026 18.5 0.2 0.0089 16.9 0.2 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat Vps39_1 PF10366.9 CCH59030.1 - 0.0043 17.3 0.3 0.085 13.1 0.0 3.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Nop14 PF04147.12 CCH59030.1 - 0.28 9.3 32.4 0.43 8.7 32.4 1.2 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 CCH59030.1 - 2.6 7.2 4.4 4.1 6.5 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.12 CCH59030.1 - 3.3 6.9 31.1 5.8 6.1 31.1 1.3 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 CCH59030.1 - 4.6 5.4 27.2 7.4 4.7 27.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Tfb5 PF06331.12 CCH59031.1 - 8.4e-26 89.8 0.0 9.6e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 RhoGAP PF00620.27 CCH59032.1 - 9.8e-38 129.4 0.0 3.6e-37 127.5 0.0 2.1 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 CCH59032.1 - 2.1e-15 56.8 1.7 2.1e-15 56.8 1.7 4.8 5 0 0 5 5 5 1 RasGEF N-terminal motif RasGEF PF00617.19 CCH59032.1 - 6e-13 49.4 0.4 6e-13 49.4 0.4 4.0 4 1 0 4 4 4 1 RasGEF domain PH PF00169.29 CCH59032.1 - 7.2e-05 23.3 0.1 0.00049 20.6 0.0 2.6 2 0 0 2 2 2 1 PH domain DUF4400 PF14348.6 CCH59032.1 - 7.9 5.9 5.6 28 4.1 5.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) 60KD_IMP PF02096.20 CCH59033.1 - 4.8e-22 78.6 1.3 4.8e-22 78.6 1.3 2.3 2 0 0 2 2 2 1 60Kd inner membrane protein PET122 PF05476.11 CCH59034.1 - 2e-53 181.3 4.2 2.5e-53 181.0 4.2 1.0 1 0 0 1 1 1 1 PET122 SWIM PF04434.17 CCH59035.1 - 0.0083 15.8 3.6 0.11 12.2 0.1 2.4 2 0 0 2 2 2 2 SWIM zinc finger UCH PF00443.29 CCH59036.1 - 4.8e-49 167.2 4.2 4.8e-49 167.2 4.2 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Xpo1 PF08389.12 CCH59037.1 - 5.2e-35 120.7 0.2 5.2e-35 120.7 0.2 4.8 6 0 0 6 6 6 1 Exportin 1-like protein DUF1345 PF07077.11 CCH59037.1 - 0.082 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) AAA PF00004.29 CCH59038.1 - 2.3e-16 60.4 0.1 8.6e-16 58.6 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CCH59038.1 - 7.4e-13 48.7 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CCH59038.1 - 1.2e-12 47.9 0.4 3.2e-11 43.3 0.1 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CCH59038.1 - 3.2e-08 33.7 0.0 7.9e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CCH59038.1 - 4.6e-05 23.2 0.0 0.00024 20.9 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CCH59038.1 - 4.9e-05 23.2 0.8 9.7e-05 22.3 0.2 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCH59038.1 - 0.00022 21.5 0.3 0.0091 16.3 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CCH59038.1 - 0.00024 20.9 0.0 0.00047 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH59038.1 - 0.00065 20.1 0.0 0.019 15.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CCH59038.1 - 0.00089 18.5 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CCH59038.1 - 0.0036 16.7 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCH59038.1 - 0.0039 17.5 0.1 0.035 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCH59038.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 CCH59038.1 - 0.0068 16.7 0.0 0.017 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain ResIII PF04851.15 CCH59038.1 - 0.016 15.3 0.0 0.16 12.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PE-PPE PF08237.11 CCH59038.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF2075 PF09848.9 CCH59038.1 - 0.02 14.2 0.0 0.069 12.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 CCH59038.1 - 0.021 14.6 0.1 0.16 11.8 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.14 CCH59038.1 - 0.026 14.5 0.2 0.41 10.6 0.2 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CCH59038.1 - 0.026 14.3 0.0 0.068 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCH59038.1 - 0.2 11.8 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Yae1_N PF09811.9 CCH59039.1 - 1.4e-11 43.9 0.0 2e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal P5CR_dimer PF14748.6 CCH59039.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation CN_hydrolase PF00795.22 CCH59040.1 - 2.6e-11 43.4 0.0 9.5e-08 31.7 0.0 3.1 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase DUF4458 PF14660.6 CCH59040.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) LicD PF04991.13 CCH59041.1 - 5.2e-36 124.9 3.8 5.2e-36 124.9 3.8 4.0 3 1 1 5 5 5 1 LicD family Pkinase PF00069.25 CCH59042.1 - 6.1e-37 127.4 0.0 1.1e-36 126.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59042.1 - 6.9e-18 64.9 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCH59042.1 - 0.00079 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH59042.1 - 0.0014 18.6 0.2 0.003 17.5 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCH59042.1 - 0.0038 16.6 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CCH59042.1 - 0.0068 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family AAA PF00004.29 CCH59043.1 - 3.8e-51 173.0 0.0 1.2e-42 145.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CCH59043.1 - 6.5e-21 74.5 0.8 2e-20 72.9 0.8 2.0 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 CCH59043.1 - 4.7e-13 48.7 0.0 5.2e-11 42.2 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CCH59043.1 - 2.3e-08 34.6 0.0 0.003 18.0 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 CCH59043.1 - 1e-05 26.1 0.8 0.019 15.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CCH59043.1 - 1.6e-05 25.0 5.6 0.04 13.9 0.1 3.7 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 CCH59043.1 - 4.6e-05 23.7 0.5 0.24 11.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CCH59043.1 - 7e-05 22.6 0.0 0.0028 17.4 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CCH59043.1 - 9.7e-05 22.7 0.2 0.14 12.6 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 CCH59043.1 - 0.00054 19.7 0.1 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CCH59043.1 - 0.00059 20.0 0.0 0.058 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCH59043.1 - 0.00074 19.7 0.0 0.022 14.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCH59043.1 - 0.00096 19.1 1.7 1.8 8.5 0.0 3.4 3 1 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 CCH59043.1 - 0.0012 19.1 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCH59043.1 - 0.0013 18.5 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_3 PF07726.11 CCH59043.1 - 0.0032 17.3 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CCH59043.1 - 0.0032 17.4 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CCH59043.1 - 0.011 14.9 0.2 0.038 13.2 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain ABC_tran PF00005.27 CCH59043.1 - 0.012 16.1 0.1 2.2 8.8 0.0 3.3 2 2 1 3 3 3 0 ABC transporter ATPase_2 PF01637.18 CCH59043.1 - 0.014 15.3 0.0 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CCH59043.1 - 0.016 15.2 0.3 0.17 11.9 0.0 2.7 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CCH59043.1 - 0.024 14.4 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 CCH59043.1 - 0.1 13.1 0.1 0.44 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 CCH59044.1 - 8e-53 178.2 5.5 9e-53 178.0 5.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pox_A6 PF04924.12 CCH59044.1 - 0.0076 15.3 0.5 0.011 14.8 0.5 1.2 1 0 0 1 1 1 1 Poxvirus A6 protein DUF4588 PF15251.6 CCH59045.1 - 4.6e-07 29.9 9.5 1.1e-06 28.6 9.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SUR7 PF06687.12 CCH59046.1 - 9.2e-24 84.2 11.1 1.4e-23 83.6 11.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family DUF4231 PF14015.6 CCH59046.1 - 0.058 13.9 1.7 0.2 12.2 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) SIT PF15330.6 CCH59046.1 - 0.13 12.7 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT MFS_1 PF07690.16 CCH59046.1 - 0.24 10.3 13.1 0.46 9.3 13.1 1.4 1 0 0 1 1 1 0 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 CCH59047.1 - 3.3e-06 27.9 0.0 4.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCH59047.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Suc_Fer-like PF06999.12 CCH59048.1 - 2.5e-35 122.1 0.0 3.2e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Gsf2 PF11055.8 CCH59049.1 - 2.5e-158 526.7 0.1 3.1e-158 526.4 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 BUD22 PF09073.10 CCH59052.1 - 0.00038 19.9 19.6 0.00054 19.4 19.6 1.1 1 0 0 1 1 1 1 BUD22 LRR_8 PF13855.6 CCH59052.1 - 0.21 11.4 9.5 0.17 11.7 1.5 4.1 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.6 CCH59052.1 - 0.97 9.7 11.7 1.8 8.8 0.2 5.9 7 0 0 7 7 7 0 Leucine Rich repeat VasI PF11319.8 CCH59052.1 - 1.4 8.5 7.2 0.095 12.4 1.2 1.9 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 LRR_4 PF12799.7 CCH59052.1 - 2.5 8.7 25.6 3.6 8.2 2.3 6.2 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) CcdA PF07362.12 CCH59052.1 - 4 8.0 8.2 0.41 11.1 0.6 2.9 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA FAD_binding_2 PF00890.24 CCH59053.1 - 1.7e-73 248.1 0.0 2e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCH59053.1 - 5.6e-08 32.8 0.0 8.7e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CCH59053.1 - 1.1e-07 31.3 0.2 1.1e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CCH59053.1 - 5.7e-07 29.7 0.0 4.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCH59053.1 - 9.4e-05 21.8 0.2 0.00032 20.0 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCH59053.1 - 0.001 18.4 0.1 0.54 9.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCH59053.1 - 0.0012 18.2 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCH59053.1 - 0.0016 17.2 2.3 0.058 12.1 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 CCH59053.1 - 0.0027 16.8 0.0 0.013 14.6 0.1 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 CCH59053.1 - 0.0073 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 CCH59053.1 - 0.04 13.0 2.9 0.055 12.6 0.1 2.5 3 1 1 4 4 4 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CCH59053.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding MCRA PF06100.11 CCH59053.1 - 0.13 11.0 0.0 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 CCH59053.1 - 0.23 10.6 0.1 0.36 10.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Isy1 PF06246.12 CCH59054.1 - 5.8e-28 98.1 10.1 6.6e-28 98.0 10.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family FliD_N PF02465.18 CCH59054.1 - 0.51 11.1 5.0 0.16 12.7 1.7 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Oxidored_FMN PF00724.20 CCH59055.1 - 2.3e-121 405.2 0.0 2.7e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GDA1_CD39 PF01150.17 CCH59056.1 - 2e-25 89.4 0.0 2.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Porin_8 PF16966.5 CCH59056.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Porin-like glycoporin RafY DUF4811 PF16069.5 CCH59056.1 - 0.048 13.5 0.9 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) NAD_kinase PF01513.21 CCH59057.1 - 8.4e-71 238.5 0.0 2e-70 237.3 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CCH59057.1 - 0.013 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Phage_TAC_12 PF12363.8 CCH59057.1 - 0.056 13.8 0.4 0.16 12.4 0.2 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC UBA PF00627.31 CCH59058.1 - 8.1e-28 95.9 6.2 1.3e-14 53.8 1.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CCH59058.1 - 1.9e-14 53.2 0.4 7.9e-14 51.2 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.11 CCH59058.1 - 1.2e-11 44.1 1.0 1.2e-11 44.1 1.0 2.0 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.8 CCH59058.1 - 3.3e-05 23.6 0.9 7.7e-05 22.4 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCH59058.1 - 6.5e-05 23.2 0.9 0.00013 22.2 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CCH59058.1 - 0.0095 16.5 0.1 0.024 15.2 0.1 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCH59058.1 - 0.0096 16.0 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1296 PF06972.11 CCH59058.1 - 0.013 15.6 0.0 0.038 14.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) CUE PF02845.16 CCH59058.1 - 0.046 13.4 0.1 8.5 6.2 0.0 3.9 4 0 0 4 4 4 0 CUE domain UBA_2 PF08587.11 CCH59058.1 - 0.072 13.2 0.1 0.28 11.3 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) RepB PF07506.11 CCH59058.1 - 0.076 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein Anp1 PF03452.14 CCH59059.1 - 7.1e-114 379.7 0.0 1.6e-113 378.5 0.0 1.6 1 0 0 1 1 1 1 Anp1 GldH_lipo PF14109.6 CCH59059.1 - 0.073 13.8 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 GldH lipoprotein DUF3752 PF12572.8 CCH59059.1 - 1.3 9.5 11.8 0.076 13.5 5.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DUF4407 PF14362.6 CCH59059.1 - 4.6 6.5 19.3 7 5.9 19.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 CCH59059.1 - 9.9 6.7 12.9 7 7.2 4.7 3.0 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) eIF-5a PF01287.20 CCH59060.1 - 1.9e-29 101.6 0.2 2.7e-29 101.1 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CCH59060.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain MCM PF00493.23 CCH59061.1 - 1.9e-97 324.7 0.5 3.8e-97 323.8 0.5 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCH59061.1 - 9.6e-32 109.5 0.0 1.9e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCH59061.1 - 4.9e-24 84.6 1.4 9.4e-24 83.6 1.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CCH59061.1 - 1.5e-07 31.0 0.0 1.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 CCH59061.1 - 1.8e-05 25.2 0.4 9.8e-05 22.9 0.1 2.4 2 1 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 CCH59061.1 - 0.0029 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCH59061.1 - 0.006 16.3 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain E1-E2_ATPase PF00122.20 CCH59062.1 - 1.2e-17 64.0 0.1 2.3e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH59062.1 - 7.9e-17 62.2 0.0 5.6e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH59062.1 - 1.2e-05 25.3 0.0 3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCH59062.1 - 0.00077 19.3 0.6 0.0094 15.7 1.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CCH59062.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase HSP70 PF00012.20 CCH59063.1 - 2.9e-266 884.4 15.1 3.3e-266 884.2 15.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH59063.1 - 2.5e-15 56.1 1.8 1.2e-12 47.3 0.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCH59063.1 - 0.00033 20.5 0.0 0.00091 19.0 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCH59063.1 - 0.021 15.2 9.2 0.74 10.3 0.3 4.2 3 2 0 3 3 3 0 Cell division protein FtsA DUF5321 PF17254.2 CCH59063.1 - 0.12 11.9 8.7 0.041 13.3 1.6 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5321) Big_3_4 PF13754.6 CCH59063.1 - 0.12 12.1 0.0 6.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF4473 PF14747.6 CCH59063.1 - 0.23 12.0 7.5 0.62 10.7 2.9 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4473) Syntaxin_2 PF14523.6 CCH59063.1 - 0.61 10.5 11.5 0.24 11.8 2.6 2.6 1 1 1 2 2 2 0 Syntaxin-like protein Spectrin PF00435.21 CCH59063.1 - 3.5 8.2 10.0 11 6.6 10.0 1.8 1 1 0 1 1 1 0 Spectrin repeat CoA_binding PF02629.19 CCH59064.1 - 1.1e-24 87.0 1.8 2.5e-24 85.8 0.2 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CCH59064.1 - 3.4e-21 75.7 0.1 6.4e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CCH59064.1 - 4.1e-08 33.1 0.1 6.7e-08 32.4 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CCH59064.1 - 0.0064 17.0 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Toprim_Crpt PF13342.6 CCH59064.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase UBA PF00627.31 CCH59065.1 - 4.9e-11 42.3 1.0 2.2e-10 40.2 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.16 CCH59065.1 - 0.00082 19.0 0.6 0.003 17.2 0.0 2.4 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 CCH59065.1 - 0.0024 17.7 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Iso_dh PF00180.20 CCH59066.1 - 3.3e-101 338.9 0.0 3.7e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1564 PF07600.11 CCH59066.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Ribosomal_L27A PF00828.19 CCH59067.1 - 9.9e-34 116.8 3.6 9.9e-34 116.8 3.6 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A CPL PF08144.11 CCH59070.1 - 1.5e-33 116.1 5.4 2.9e-31 108.7 1.3 4.7 3 2 1 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 CCH59070.1 - 1.1e-09 37.5 2.2 0.16 11.7 0.0 6.6 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat DUF4253 PF14062.6 CCH59070.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) FANCI_S2 PF14676.6 CCH59070.1 - 0.11 12.7 1.6 1.2 9.4 0.3 3.2 2 1 0 2 2 2 0 FANCI solenoid 2 INO80_Ies4 PF08193.11 CCH59070.1 - 0.45 10.5 9.7 0.68 9.9 9.7 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 CDC45 PF02724.14 CCH59070.1 - 0.68 8.2 16.7 1.2 7.4 16.7 1.4 1 0 0 1 1 1 0 CDC45-like protein HlyIII PF03006.20 CCH59071.1 - 5.7e-50 170.1 19.5 7.1e-50 169.8 19.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related COX6A PF02046.15 CCH59071.1 - 0.16 12.5 0.2 0.82 10.2 0.0 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VIa DUF613 PF04764.12 CCH59071.1 - 0.17 12.1 1.2 16 5.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF613) SepSecS PF05889.13 CCH59071.1 - 0.19 10.4 0.2 0.28 9.8 0.2 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS MerC PF03203.14 CCH59071.1 - 1 9.8 7.3 1.8 9.0 0.3 3.2 1 1 2 3 3 3 0 MerC mercury resistance protein LapA_dom PF06305.11 CCH59071.1 - 3.2 7.6 5.2 3 7.7 0.2 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Draxin PF15550.6 CCH59072.1 - 0.031 14.1 0.0 0.036 14.0 0.0 1.0 1 0 0 1 1 1 0 Draxin Pkinase PF00069.25 CCH59073.1 - 3.9e-51 174.0 0.0 9.6e-50 169.4 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59073.1 - 3.8e-27 95.2 0.0 2.4e-26 92.6 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59073.1 - 0.00024 20.5 0.0 0.00047 19.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCH59073.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH59073.1 - 0.018 15.0 4.8 1.4 8.7 0.4 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCH59073.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 tRNA-synt_1b PF00579.25 CCH59074.1 - 1.1e-19 70.9 0.0 7.6e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Methyltransf_23 PF13489.6 CCH59075.1 - 8.5e-23 81.0 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH59075.1 - 1.6e-17 63.9 0.0 3.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH59075.1 - 7.6e-16 58.3 0.0 1.1e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH59075.1 - 2.1e-14 54.0 0.0 5.4e-14 52.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH59075.1 - 4.2e-13 49.9 0.0 8.8e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH59075.1 - 9.4e-08 31.7 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 CCH59075.1 - 8.8e-07 28.6 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CCH59075.1 - 5.7e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CCH59075.1 - 6.8e-06 25.8 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CCH59075.1 - 8.8e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 CCH59075.1 - 0.00011 21.5 0.0 0.00023 20.4 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase MetW PF07021.12 CCH59075.1 - 0.00025 20.7 0.0 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CCH59075.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCH59075.1 - 0.0022 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_LP_H2 PF03356.15 CCH59075.1 - 0.0078 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Viral late protein H2 Methyltransf_18 PF12847.7 CCH59075.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CCH59075.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UvrD-helicase PF00580.21 CCH59076.1 - 1.1e-30 107.3 13.5 1.4e-27 97.0 5.4 3.1 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CCH59076.1 - 6e-27 94.8 0.0 1.2e-26 93.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 CCH59076.1 - 2.4e-22 79.8 5.2 2.4e-22 79.8 5.2 3.0 2 2 1 3 3 3 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CCH59076.1 - 1.9e-10 40.9 0.0 0.0006 19.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CCH59076.1 - 3.8e-10 39.4 0.0 7.2e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CCH59076.1 - 2.8e-06 27.3 0.4 1.7e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH59076.1 - 0.0078 15.9 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CCH59076.1 - 0.011 15.8 2.2 0.26 11.3 0.0 2.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MRP-S23 PF10484.9 CCH59076.1 - 0.019 15.2 1.4 0.11 12.8 0.4 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 CCM2_C PF16545.5 CCH59076.1 - 0.045 14.3 3.3 13 6.4 0.0 3.7 4 0 0 4 4 4 0 Cerebral cavernous malformation protein, harmonin-homology AP4E_app_platf PF14807.6 CCH59076.1 - 0.078 13.3 0.4 1.5 9.2 0.3 2.6 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform AAA_22 PF13401.6 CCH59076.1 - 0.13 12.5 0.1 14 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF4600 PF15372.6 CCH59076.1 - 0.38 11.2 5.1 7.3 7.1 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) DnaB_2 PF07261.11 CCH59076.1 - 3.2 7.6 10.9 1.4 8.7 0.6 4.7 5 0 0 5 5 5 0 Replication initiation and membrane attachment Vps52 PF04129.12 CCH59077.1 - 3.1e-143 478.2 22.7 4.1e-143 477.8 22.7 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Peptidase_C12 PF01088.21 CCH59077.1 - 0.0084 15.9 0.3 0.02 14.6 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF4942 PF13708.6 CCH59077.1 - 0.019 15.0 0.5 0.046 13.7 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Baculo_PEP_C PF04513.12 CCH59077.1 - 0.23 11.5 7.3 0.097 12.7 2.3 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 CCH59077.1 - 0.58 10.2 8.2 4.4 7.3 2.0 3.2 1 1 1 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.20 CCH59077.1 - 6.8 6.7 10.6 37 4.3 0.1 4.3 3 2 0 4 4 4 0 Prefoldin subunit tRNA_m1G_MT PF01746.21 CCH59078.1 - 1e-34 120.0 0.4 1.5e-34 119.4 0.4 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF4542 PF15075.6 CCH59079.1 - 0.013 15.9 0.4 0.063 13.7 0.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4542) Pox_G9-A16 PF03003.16 CCH59079.1 - 0.088 12.5 5.9 0.067 12.9 2.8 2.5 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 DASH_Dam1 PF08653.10 CCH59079.1 - 1 9.2 4.7 2.2 8.1 0.3 3.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF489 PF04356.12 CCH59079.1 - 5.6 6.9 13.0 1.2 9.1 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF489) MutS_V PF00488.21 CCH59080.1 - 2.7e-85 285.2 0.3 7e-85 283.8 0.3 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCH59080.1 - 1.5e-31 110.2 1.4 1.5e-31 110.2 1.4 2.5 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 CCH59080.1 - 1.6e-20 73.8 2.1 1.7e-20 73.7 0.2 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CCH59080.1 - 2.1e-19 69.6 1.8 2.1e-19 69.6 1.8 2.9 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 CCH59080.1 - 1e-10 41.8 0.1 8.6e-10 38.9 0.0 2.4 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 CCH59080.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CCH59080.1 - 0.41 11.0 6.1 1.4e+02 2.7 6.1 3.3 1 1 0 1 1 1 0 AAA domain OSCP PF00213.18 CCH59080.1 - 1.3 9.1 5.9 0.26 11.4 0.2 2.7 3 0 0 3 3 3 0 ATP synthase delta (OSCP) subunit Hist_deacetyl PF00850.19 CCH59081.1 - 4.4e-70 236.6 0.0 2e-69 234.4 0.0 1.9 1 1 0 1 1 1 1 Histone deacetylase domain Con-6 PF10346.9 CCH59081.1 - 0.0046 17.0 0.1 0.056 13.5 0.1 2.4 2 0 0 2 2 2 1 Conidiation protein 6 EF-hand_1 PF00036.32 CCH59082.1 - 2.8e-28 95.3 4.9 3.7e-08 32.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCH59082.1 - 9.8e-26 90.0 0.4 5.6e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCH59082.1 - 6.6e-25 84.9 2.9 5.5e-08 32.1 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CCH59082.1 - 8e-18 63.1 2.6 4.9e-07 29.0 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CCH59082.1 - 3.6e-15 55.5 4.6 2.4e-08 33.7 0.0 3.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CCH59082.1 - 4.4e-13 49.3 0.0 3.5e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCH59082.1 - 2e-05 24.9 0.1 0.017 15.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CCH59082.1 - 2.3e-05 24.6 0.1 0.23 11.8 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CCH59082.1 - 0.00067 19.6 0.0 0.085 12.9 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 CCH59082.1 - 0.00068 19.8 1.2 0.086 13.0 0.1 2.7 1 1 2 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 CCH59082.1 - 0.01 15.8 0.0 3.4 7.5 0.0 2.8 1 1 2 3 3 3 0 Caleosin related protein TerB PF05099.13 CCH59082.1 - 0.012 15.6 0.1 0.077 13.0 0.0 2.0 1 1 0 2 2 2 0 Tellurite resistance protein TerB EF-hand_11 PF08976.11 CCH59082.1 - 0.012 16.5 0.0 3.2 8.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain DUF853 PF05872.12 CCH59082.1 - 0.013 14.1 0.4 0.053 12.1 0.2 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_4 PF12763.7 CCH59082.1 - 0.016 15.2 1.2 0.055 13.4 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand RNA_pol_Rpb4 PF03874.16 CCH59082.1 - 0.028 14.7 1.1 0.33 11.3 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 GPHH PF16905.5 CCH59082.1 - 0.08 12.7 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated SAWADEE PF16719.5 CCH59083.1 - 0.019 15.0 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 SAWADEE domain CENP-L PF13092.6 CCH59083.1 - 0.098 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DnaJ PF00226.31 CCH59084.1 - 0.0027 17.8 3.4 0.081 13.1 3.4 2.6 1 1 0 1 1 1 1 DnaJ domain CM_2 PF01817.21 CCH59085.1 - 0.042 14.2 0.0 0.15 12.5 0.0 1.9 1 1 0 1 1 1 0 Chorismate mutase type II Mito_carr PF00153.27 CCH59086.1 - 1.5e-60 201.1 3.0 4.1e-20 71.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SIP1 PF04938.12 CCH59087.1 - 3.4e-06 26.9 7.0 8.3e-06 25.7 7.0 1.7 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Tfb4 PF03850.14 CCH59089.1 - 2.7e-104 348.5 3.7 3.2e-104 348.3 3.7 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Cucumopine_C PF18631.1 CCH59089.1 - 0.0056 16.6 0.1 5.3 7.0 0.0 2.8 3 0 0 3 3 3 2 Cucumopine synthase C-terminal helical bundle domain Rad50_zn_hook PF04423.14 CCH59089.1 - 0.088 12.7 0.1 0.29 11.0 0.1 1.9 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF4776 PF16003.5 CCH59089.1 - 1.7 7.5 7.8 0.34 9.8 2.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4776) ANAPC4_WD40 PF12894.7 CCH59090.1 - 1.3e-08 35.0 4.1 0.0099 16.2 0.3 5.6 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH59090.1 - 2.3e-08 34.5 4.3 1.3 10.0 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat LisH PF08513.11 CCH59090.1 - 1.2e-05 25.1 0.1 2.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 LisH HPS3_N PF14761.6 CCH59090.1 - 0.0019 17.8 0.2 0.0047 16.5 0.2 1.6 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 LKAAEAR PF15478.6 CCH59090.1 - 1 9.6 4.8 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif Exo84_C PF16528.5 CCH59091.1 - 3e-53 180.7 12.1 3e-53 180.7 12.1 2.5 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CCH59091.1 - 2.2e-07 30.9 5.2 2.2e-07 30.9 5.2 2.9 3 0 0 3 3 3 1 Vps51/Vps67 Fzo_mitofusin PF04799.13 CCH59091.1 - 0.0058 16.2 1.7 0.0058 16.2 1.7 2.4 3 0 0 3 3 3 1 fzo-like conserved region Leuk-A4-hydro_C PF09127.11 CCH59091.1 - 0.047 13.8 2.7 6.2 6.9 0.1 3.7 3 0 0 3 3 3 0 Leukotriene A4 hydrolase, C-terminal Fes1 PF08609.10 CCH59092.1 - 6.8e-18 65.4 1.6 6.8e-18 65.4 1.6 3.0 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 CDC14 PF08045.11 CCH59092.1 - 0.00016 20.9 8.1 0.00041 19.5 8.1 2.0 1 1 0 1 1 1 1 Cell division control protein 14, SIN component V-ATPase_H_C PF11698.8 CCH59092.1 - 0.00061 19.9 2.1 0.00061 19.9 2.1 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Prenyltransf PF01255.19 CCH59092.1 - 0.069 12.7 0.5 0.16 11.4 0.5 1.7 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase ERCC4 PF02732.15 CCH59093.1 - 1.4e-13 51.3 7.4 1.4e-13 51.3 7.4 2.6 1 1 1 2 2 2 1 ERCC4 domain DUF3276 PF11680.8 CCH59093.1 - 0.11 12.6 4.0 0.09 12.9 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Sec8_exocyst PF04048.14 CCH59094.1 - 2.7e-34 118.1 4.1 2.7e-34 118.1 4.1 3.7 4 0 0 4 4 4 2 Sec8 exocyst complex component specific domain 4HBT_2 PF13279.6 CCH59095.1 - 8.5e-11 42.4 0.0 1.4e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF5478 PF17572.2 CCH59095.1 - 0.033 14.3 0.2 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5478) TTL PF03133.15 CCH59096.1 - 4.5e-76 255.8 6.3 8.4e-76 254.9 6.3 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 CCH59096.1 - 3.1e-43 147.8 0.0 5.4e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 CCH59096.1 - 0.00012 21.4 0.1 0.021 14.1 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp RhoGAP PF00620.27 CCH59096.1 - 0.071 12.9 0.7 2.7 7.8 0.1 2.5 2 0 0 2 2 2 0 RhoGAP domain DUF3853 PF12964.7 CCH59096.1 - 0.17 12.0 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) zf-Tim10_DDP PF02953.15 CCH59097.1 - 1.2e-15 56.9 1.3 1.7e-15 56.4 1.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PCNA_N PF00705.18 CCH59098.1 - 1.2e-54 183.4 1.3 6.8e-54 181.0 1.8 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CCH59098.1 - 4.6e-47 159.4 0.0 1e-46 158.2 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CCH59098.1 - 0.00032 19.9 0.1 0.0036 16.4 0.1 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Acetyltransf_1 PF00583.25 CCH59099.1 - 7.4e-19 68.1 0.0 9.3e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCH59099.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCH59099.1 - 2.5e-11 43.6 0.0 3.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCH59099.1 - 5.1e-09 36.0 0.0 7.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CCH59099.1 - 3.1e-06 27.9 0.0 3.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CCH59099.1 - 3.6e-06 26.7 0.0 5.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCH59099.1 - 1.9e-05 24.8 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCH59099.1 - 0.0034 17.5 0.0 0.025 14.7 0.0 2.4 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CCH59099.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 CCH59099.1 - 0.025 14.7 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCH59099.1 - 0.027 13.9 0.2 0.068 12.6 0.2 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase DUF1073 PF06381.11 CCH59099.1 - 0.085 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) ATG11 PF10377.9 CCH59100.1 - 1.5e-34 118.8 0.1 1.5e-34 118.8 0.1 3.0 3 0 0 3 3 3 1 Autophagy-related protein 11 DUF919 PF06034.11 CCH59100.1 - 4.8 7.1 15.0 0.089 12.6 1.3 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF919) FAD_binding_1 PF00667.20 CCH59101.1 - 1.7e-27 96.5 0.0 3.7e-27 95.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCH59101.1 - 8.4e-19 68.2 0.0 1.9e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCH59101.1 - 1.6e-11 44.8 0.0 3.6e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain tRNA-synt_2d PF01409.20 CCH59102.1 - 1.8e-39 135.7 0.0 1.5e-23 83.6 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CCH59102.1 - 7.1e-22 77.6 0.3 1.9e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Ribosomal_L16 PF00252.18 CCH59103.1 - 1.3e-35 122.2 0.1 1.8e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol3_delta2 PF13177.6 CCH59104.1 - 7.5e-09 35.6 3.1 1.5e-08 34.6 0.5 2.4 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 CCH59104.1 - 1.7e-07 31.7 0.6 4.8e-06 27.0 0.1 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CCH59104.1 - 0.00011 22.3 0.1 0.00032 20.7 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 CCH59104.1 - 0.011 15.4 0.0 0.05 13.4 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCH59104.1 - 0.021 15.1 0.4 0.18 12.0 0.1 2.6 2 2 0 2 2 2 0 AAA domain Rep_fac_C PF08542.11 CCH59104.1 - 0.026 14.9 0.1 0.13 12.7 0.0 2.3 2 1 0 2 2 2 0 Replication factor C C-terminal domain AAA_5 PF07728.14 CCH59104.1 - 0.037 14.0 0.0 0.096 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCH59104.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DASH_Dad4 PF08650.10 CCH59104.1 - 0.18 11.8 3.6 0.64 10.0 0.3 3.3 4 0 0 4 4 4 0 DASH complex subunit Dad4 Anoctamin PF04547.12 CCH59105.1 - 5.5e-43 147.4 35.0 1e-41 143.3 35.0 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel ORF6N PF10543.9 CCH59105.1 - 0.045 13.9 0.1 0.21 11.8 0.1 2.2 1 0 0 1 1 1 0 ORF6N domain Pol_alpha_B_N PF08418.10 CCH59106.1 - 2.2e-60 204.7 2.8 3e-60 204.2 2.8 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CCH59106.1 - 9.8e-46 155.8 0.8 1.6e-45 155.1 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CLASP_N PF12348.8 CCH59107.1 - 6.7e-62 209.0 18.5 1.2e-60 204.9 6.6 2.8 2 0 0 2 2 2 2 CLASP N terminal MRP-S33 PF08293.11 CCH59107.1 - 0.0095 16.2 0.1 0.061 13.6 0.1 2.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gastrin PF00918.17 CCH59107.1 - 2.5 9.1 4.9 1.4 9.9 0.1 2.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family zf-RING_UBOX PF13445.6 CCH59109.1 - 1.6e-08 34.4 8.7 1.6e-08 34.4 8.7 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCH59109.1 - 5.9e-08 32.4 14.0 1.9e-07 30.8 6.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH59109.1 - 2.3e-07 30.6 9.8 2.3e-07 30.6 9.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH59109.1 - 2.8e-07 30.6 13.7 2.8e-07 30.6 13.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CCH59109.1 - 5.6e-07 29.8 11.4 5.6e-07 29.8 11.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCH59109.1 - 2.4e-06 27.3 10.8 2.4e-06 27.3 10.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH59109.1 - 2.4e-05 24.1 16.6 2.5e-05 24.0 8.6 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CCH59109.1 - 0.0042 17.0 9.5 0.0042 17.0 9.5 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zinc_ribbon_2 PF13240.6 CCH59109.1 - 0.067 12.9 7.5 3.8 7.3 2.6 4.0 2 1 1 3 3 3 0 zinc-ribbon domain zf-UDP PF14569.6 CCH59109.1 - 0.2 11.8 0.1 0.2 11.8 0.1 3.5 3 1 0 3 3 2 0 Zinc-binding RING-finger zf-rbx1 PF12678.7 CCH59109.1 - 0.39 11.0 11.6 0.53 10.6 8.9 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCH59109.1 - 0.78 9.8 7.6 0.12 12.5 3.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_Tnp_IS1595 PF12760.7 CCH59109.1 - 1.1 9.3 9.8 2.5 8.2 0.1 3.3 3 0 0 3 3 3 0 Transposase zinc-ribbon domain HypA PF01155.19 CCH59109.1 - 1.5 8.9 7.1 0.51 10.4 0.1 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CCH59109.1 - 2.2 8.4 12.6 0.3 11.1 0.2 3.1 2 1 0 2 2 2 0 Double zinc ribbon EamA PF00892.20 CCH59111.1 - 3.8e-27 95.1 30.6 2e-15 57.1 9.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CCH59111.1 - 0.0071 15.3 6.9 0.012 14.6 6.8 1.6 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like RseC_MucC PF04246.12 CCH59111.1 - 0.062 13.3 7.6 4.5 7.2 0.0 3.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TPT PF03151.16 CCH59111.1 - 1.8 7.9 10.8 0.033 13.5 3.4 1.8 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF2070 PF09843.9 CCH59111.1 - 6.6 4.9 25.1 0.12 10.6 5.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) SAM_decarbox PF01536.16 CCH59113.1 - 2.4e-128 428.1 3.2 2.8e-128 427.9 3.2 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Latarcin PF10279.9 CCH59114.1 - 0.11 12.9 0.8 0.55 10.7 0.4 2.3 2 0 0 2 2 2 0 Latarcin precursor MRP-S33 PF08293.11 CCH59114.1 - 0.35 11.1 2.1 0.46 10.8 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 RRM_1 PF00076.22 CCH59115.1 - 9.8e-21 73.4 3.7 7.2e-13 48.2 0.3 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH59115.1 - 6.6e-06 26.2 0.4 0.0056 16.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCH59115.1 - 0.032 14.2 0.2 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.28 CCH59116.1 - 2.7e-93 312.9 0.0 4.5e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCH59116.1 - 0.00042 21.2 0.0 0.0018 19.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mitovir_RNA_pol PF05919.11 CCH59116.1 - 0.21 10.7 1.7 0.19 10.9 0.3 1.6 2 0 0 2 2 2 0 Mitovirus RNA-dependent RNA polymerase Flp_C PF05202.12 CCH59117.1 - 5.9e-23 81.7 1.0 1.1e-22 80.7 1.0 1.4 1 0 0 1 1 1 1 Recombinase Flp protein Flp_N PF03930.14 CCH59117.1 - 0.00023 21.1 1.2 0.00059 19.8 1.2 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus COX6B PF02297.17 CCH59118.1 - 1.9e-19 69.7 4.7 2.6e-19 69.2 4.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 CCH59118.1 - 0.0066 16.7 0.7 0.012 15.8 0.5 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 CCH59118.1 - 0.041 14.2 0.9 8.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Bac_rhodopsin PF01036.18 CCH59119.1 - 1e-48 165.9 14.8 1.3e-48 165.5 14.8 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4504 PF14953.6 CCH59119.1 - 0.48 9.8 2.8 3.4 7.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4504) ATPase_gene1 PF09527.10 CCH59119.1 - 1.2 9.3 13.6 0.73 10.1 1.2 2.9 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter SUN PF03856.13 CCH59120.1 - 2.1e-85 286.1 18.7 2.5e-85 285.8 18.7 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Atrophin-1 PF03154.15 CCH59122.1 - 2.9e-05 22.6 0.2 2.9e-05 22.6 0.2 2.0 2 0 0 2 2 2 1 Atrophin-1 family Endonuc_Holl PF10107.9 CCH59122.1 - 0.026 14.4 4.7 0.079 12.8 4.7 1.8 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase NARP1 PF12569.8 CCH59122.1 - 0.57 9.0 10.5 0.99 8.2 10.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.10 CCH59122.1 - 2.3 8.3 7.4 5.5 7.0 7.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_L18A PF01775.17 CCH59123.1 - 2.3e-54 182.7 1.2 3.1e-54 182.2 1.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF1057 PF06342.12 CCH59123.1 - 0.042 12.9 0.1 0.064 12.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) CTP_transf_1 PF01148.20 CCH59124.1 - 5.7e-07 29.6 3.8 8.6e-07 29.0 3.8 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family MFS_1 PF07690.16 CCH59124.1 - 0.0079 15.2 3.4 0.012 14.6 3.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Nop PF01798.18 CCH59125.1 - 4e-82 275.1 0.2 4e-82 275.1 0.2 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCH59125.1 - 2.9e-18 66.0 1.3 2.9e-18 66.0 1.3 2.4 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 CCH59125.1 - 0.58 10.6 46.2 1 9.7 46.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 CCH59125.1 - 0.74 9.6 32.3 1.7 8.4 32.3 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM1 PF15501.6 CCH59125.1 - 2.1 7.4 33.9 2.8 7.0 33.9 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 GAGA_bind PF06217.12 CCH59125.1 - 3.2 8.0 24.0 6.3 7.0 24.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family PPP4R2 PF09184.11 CCH59125.1 - 4.9 6.7 38.8 12 5.4 0.2 2.3 2 0 0 2 2 2 0 PPP4R2 SART-1 PF03343.13 CCH59126.1 - 1.7e-71 241.7 58.1 2e-71 241.4 58.1 1.0 1 0 0 1 1 1 1 SART-1 family TPT PF03151.16 CCH59127.1 - 1.8e-30 106.3 26.9 9.4e-29 100.7 26.9 2.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CCH59127.1 - 0.0024 18.0 6.3 0.0024 18.0 6.3 4.0 3 1 0 4 4 4 3 EamA-like transporter family TMEM234 PF10639.9 CCH59127.1 - 1.2 9.2 9.5 0.33 11.0 0.6 2.8 3 0 0 3 3 3 0 Putative transmembrane family 234 UAA PF08449.11 CCH59127.1 - 1.4 8.0 23.3 0.019 14.1 9.8 2.3 2 1 0 2 2 2 0 UAA transporter family DUF2034 PF10356.9 CCH59128.1 - 2.7e-50 170.4 0.0 3.2e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CCH59128.1 - 0.0025 17.8 0.0 0.34 10.9 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease RNase_3_N PF18497.1 CCH59129.1 - 1.6e-40 137.6 0.9 3.2e-40 136.6 0.2 1.9 2 0 0 2 2 2 1 Ribonuclease III N-terminal domain Ribonuclease_3 PF00636.26 CCH59129.1 - 2.7e-17 63.3 0.0 9.5e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCH59129.1 - 2.8e-12 46.9 0.1 6.3e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CCH59129.1 - 8.2e-07 29.6 0.1 2.8e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ku PF02735.16 CCH59131.1 - 1.1e-37 129.8 0.1 2.3e-37 128.7 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CCH59131.1 - 2.4e-22 79.8 11.1 2.4e-22 79.8 11.1 2.0 1 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CCH59131.1 - 4.2e-07 30.6 7.1 1.2e-05 25.9 7.1 3.0 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 CCH59131.1 - 0.017 15.3 0.2 0.057 13.7 0.2 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain ZapD PF07072.11 CCH59131.1 - 0.16 11.7 2.3 7.9 6.2 0.1 2.3 2 0 0 2 2 2 0 Cell division protein adh_short_C2 PF13561.6 CCH59131.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Exo_endo_phos PF03372.23 CCH59132.1 - 6.9e-26 91.2 0.0 1.1e-25 90.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.20 CCH59133.1 - 9.4e-12 44.6 0.1 1.2e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNB PF00773.19 CCH59134.1 - 4.9e-66 223.3 2.1 4.9e-66 223.3 2.1 2.0 2 0 0 2 2 2 1 RNB domain SRC-1 PF08832.10 CCH59134.1 - 0.053 14.6 1.5 4.1 8.5 0.0 3.1 3 0 0 3 3 3 0 Steroid receptor coactivator RNA_pol_Rpb5_C PF01191.19 CCH59134.1 - 0.16 11.9 1.9 2.4 8.1 0.4 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Gtr1_RagA PF04670.12 CCH59135.1 - 5.3e-94 313.9 4.3 7.3e-94 313.4 4.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CCH59135.1 - 1.8e-08 34.2 0.5 5.7e-08 32.5 0.1 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CCH59135.1 - 8.5e-08 32.4 0.0 2.1e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCH59135.1 - 2.3e-07 30.9 0.0 7.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 CCH59135.1 - 1.1e-06 28.2 1.7 1.4e-06 27.9 0.2 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family ABC_tran PF00005.27 CCH59135.1 - 0.013 16.0 0.3 0.029 14.9 0.1 1.9 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 CCH59135.1 - 0.018 14.9 1.1 1.4 8.8 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 CCH59135.1 - 0.05 13.4 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain BEN PF10523.9 CCH59135.1 - 0.068 13.4 0.1 2.8 8.3 0.1 2.4 2 0 0 2 2 2 0 BEN domain AIG1 PF04548.16 CCH59135.1 - 0.22 10.8 4.0 0.33 10.2 0.1 2.6 2 2 0 3 3 3 0 AIG1 family DUF262 PF03235.14 CCH59135.1 - 1.2 9.2 7.6 0.81 9.8 5.7 1.5 1 1 0 2 2 2 0 Protein of unknown function DUF262 Sugar_tr PF00083.24 CCH59136.1 - 4.2e-42 144.5 11.4 7.8e-29 100.8 2.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CCH59136.1 - 9.1e-19 67.6 14.1 3.4e-17 62.4 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1509 PF07420.11 CCH59136.1 - 0.027 13.4 0.2 0.041 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) FAM178 PF14816.6 CCH59136.1 - 0.18 10.7 0.4 0.44 9.5 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function, FAM178 Tubulin PF00091.25 CCH59137.1 - 3.9e-68 229.6 0.0 6.2e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCH59137.1 - 1.8e-49 167.1 0.2 2.8e-49 166.5 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CCH59137.1 - 0.0034 17.1 0.0 0.047 13.4 0.0 2.3 2 0 0 2 2 2 1 Tubulin domain ALO PF04030.14 CCH59138.1 - 2.7e-102 342.0 1.2 4.4e-102 341.3 1.2 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CCH59138.1 - 5.1e-27 94.3 0.0 7.2e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SIS_2 PF13580.6 CCH59138.1 - 0.076 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 SIS domain FAD_binding_6 PF00970.24 CCH59139.1 - 1.5e-28 99.0 0.0 2.4e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCH59139.1 - 2.7e-26 92.3 0.0 3.9e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCH59139.1 - 0.00035 20.7 0.0 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CCH59139.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.8 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain F-box-like PF12937.7 CCH59140.1 - 2.1e-11 43.5 0.1 4.2e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCH59140.1 - 5.3e-08 32.5 1.1 5.3e-08 32.5 1.1 2.3 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 CCH59140.1 - 1.3e-05 24.8 29.2 0.028 14.3 3.9 4.9 4 0 0 4 4 4 4 Ubiquitin interaction motif F-box_4 PF15966.5 CCH59140.1 - 0.011 15.6 0.2 0.03 14.2 0.2 1.7 1 1 0 1 1 1 0 F-box GTP_cyclohydro2 PF00925.20 CCH59141.1 - 5.9e-54 182.1 0.0 1e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II PhzC-PhzF PF02567.16 CCH59143.1 - 6.3e-60 203.0 0.0 7.5e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pox_G9-A16 PF03003.16 CCH59143.1 - 0.076 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 Cys_Met_Meta_PP PF01053.20 CCH59144.1 - 3.6e-62 210.1 0.0 8e-62 209.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCH59144.1 - 0.00043 19.3 0.0 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V PQ-loop PF04193.14 CCH59145.1 - 3.7e-24 84.3 8.9 1.2e-19 69.8 1.8 2.9 2 1 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.6 CCH59145.1 - 7.7 6.0 25.0 1.3 8.6 13.6 2.4 1 1 2 3 3 3 0 ABC-2 family transporter protein DUF2428 PF10350.9 CCH59146.1 - 2.3e-49 168.1 0.2 1.4e-48 165.5 0.1 2.3 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CCH59146.1 - 1.3e-07 31.3 0.6 0.38 11.1 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 CCH59146.1 - 4.3e-06 27.0 0.3 0.0049 17.2 0.2 4.6 4 1 0 4 4 4 1 HEAT repeats CSTF2_hinge PF14327.6 CCH59146.1 - 2 8.9 6.9 1.4 9.4 0.2 3.6 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 Glyco_transf_20 PF00982.21 CCH59147.1 - 1.1e-164 548.6 3.7 1.2e-164 548.6 0.7 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCH59147.1 - 4.1e-37 127.5 0.5 6.8e-36 123.6 0.0 2.9 3 0 0 3 3 3 1 Trehalose-phosphatase TatD_DNase PF01026.21 CCH59148.1 - 7.4e-35 120.5 0.0 9.4e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase CUE PF02845.16 CCH59149.1 - 2.6e-08 33.4 0.0 5.6e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain Choline_kin_N PF04428.14 CCH59149.1 - 0.03 14.0 0.7 1.9 8.3 0.2 2.4 2 0 0 2 2 2 0 Choline kinase N terminus PSII PF00421.19 CCH59149.1 - 0.053 12.2 0.1 0.066 11.9 0.1 1.1 1 0 0 1 1 1 0 Photosystem II protein Ctr PF04145.15 CCH59149.1 - 0.52 10.9 3.8 1.6 9.3 3.8 1.9 1 1 0 1 1 1 0 Ctr copper transporter family MNSV_P7B PF06692.11 CCH59149.1 - 0.99 9.5 3.6 1.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein HAD_SAK_1 PF10307.9 CCH59150.1 - 2.7e-52 177.5 3.6 3.7e-52 177.1 3.6 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins RSN1_7TM PF02714.15 CCH59151.1 - 3.6e-91 305.3 28.0 3.6e-91 305.3 28.0 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCH59151.1 - 2.6e-40 137.7 0.9 2.6e-40 137.7 0.9 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCH59151.1 - 4.9e-30 105.0 1.2 8e-30 104.4 1.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CCH59151.1 - 7.7e-29 99.7 0.1 1.8e-28 98.5 0.1 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF4618 PF15397.6 CCH59151.1 - 0.36 10.2 5.3 0.044 13.2 1.2 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) AROS PF15684.5 CCH59151.1 - 3 8.4 6.5 22 5.6 0.6 2.3 2 0 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Nup188 PF10487.9 CCH59152.1 - 1.8e-280 933.0 55.2 1.8e-280 933.0 55.2 2.3 3 0 0 3 3 3 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CCH59152.1 - 3.5e-16 59.0 2.7 8.6e-16 57.7 2.7 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain RRM_1 PF00076.22 CCH59153.1 - 1.2e-28 98.7 2.8 6.8e-11 41.8 0.1 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCH59153.1 - 9.4e-28 95.9 2.7 8.9e-26 89.6 0.2 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCH59153.1 - 3.2e-05 23.8 0.0 0.005 16.8 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 CCH59153.1 - 0.00019 20.8 1.2 0.00052 19.4 0.1 2.5 2 0 0 2 2 2 1 Lsm interaction motif BRAP2 PF07576.12 CCH59153.1 - 0.0078 16.4 0.2 0.32 11.3 0.1 2.6 2 0 0 2 2 2 1 BRCA1-associated protein 2 Itfg2 PF15907.5 CCH59153.1 - 0.07 12.2 2.6 0.23 10.5 0.5 2.4 2 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF1533 PF07550.11 CCH59153.1 - 0.074 13.0 1.8 8.2 6.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) PHM7_cyt PF14703.6 CCH59153.1 - 0.21 11.8 6.5 11 6.2 0.1 4.2 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter G-patch PF01585.23 CCH59154.1 - 0.0033 17.3 1.4 0.029 14.3 1.4 2.5 1 1 0 1 1 1 1 G-patch domain DDHD PF02862.17 CCH59154.1 - 0.51 10.5 8.0 0.62 10.2 8.0 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 CCH59154.1 - 0.68 9.7 21.9 0.79 9.5 21.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 CCH59154.1 - 1.4 8.9 8.5 1.5 8.8 8.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CCH59154.1 - 2.2 8.2 6.5 2.9 7.8 6.5 1.4 1 0 0 1 1 1 0 N-glycosylation protein SLC12 PF03522.15 CCH59154.1 - 3.1 6.7 18.2 3.4 6.6 18.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2207 PF09972.9 CCH59154.1 - 3.5 6.3 10.8 3.5 6.3 10.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PA26 PF04636.13 CCH59154.1 - 7.2 5.4 11.4 8.3 5.2 11.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MCM_bind PF09739.9 CCH59154.1 - 7.3 4.9 17.8 9 4.6 17.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PXA PF02194.15 CCH59155.1 - 6.2e-35 120.8 4.4 6.2e-35 120.8 4.4 3.3 4 1 0 4 4 4 1 PXA domain Nexin_C PF08628.12 CCH59155.1 - 5.7e-21 75.2 0.7 5.7e-21 75.2 0.7 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CCH59155.1 - 4.2e-15 55.7 1.8 4.2e-15 55.7 1.8 2.4 2 0 0 2 2 2 1 PX domain zf-C2HE PF16278.5 CCH59155.1 - 0.0071 16.8 0.0 0.056 13.9 0.0 2.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger PsbX PF06596.11 CCH59155.1 - 0.17 11.9 0.1 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) RRN9 PF10680.9 CCH59156.1 - 3.2e-14 52.9 0.2 7e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor IBN_N PF03810.19 CCH59156.1 - 0.019 14.9 0.6 0.05 13.5 0.6 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain SRP19 PF01922.17 CCH59157.1 - 9.6e-27 93.8 0.0 1.7e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein DUF3600 PF12207.8 CCH59157.1 - 0.091 12.7 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3600) Pribosyltran PF00156.27 CCH59158.1 - 1.4e-17 63.7 0.2 1.8e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C3HC PF07967.13 CCH59159.1 - 1.7e-05 24.8 9.5 1.9e-05 24.7 1.5 3.1 2 2 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 CCH59159.1 - 0.02 15.0 3.7 0.3 11.3 0.1 2.8 2 1 0 2 2 2 0 Rsm1-like zinc_ribbon_5 PF13719.6 CCH59159.1 - 0.084 12.6 1.0 0.26 11.1 1.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain DUF1892 PF08987.10 CCH59160.1 - 3.5e-46 155.9 10.6 1.1e-45 154.3 10.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1892) Phage_gp53 PF11246.8 CCH59160.1 - 0.021 14.5 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Base plate wedge protein 53 Zds_C PF08632.10 CCH59161.1 - 1.1e-28 98.7 2.5 2.2e-28 97.8 2.5 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Bul1_N PF04425.12 CCH59162.1 - 5.4e-159 529.8 10.1 5.4e-159 529.8 10.1 3.0 2 1 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.12 CCH59162.1 - 5.9e-84 281.7 27.5 1.8e-58 198.1 17.7 4.0 3 2 2 5 5 5 2 Bul1 C terminus DUF5347 PF17282.2 CCH59162.1 - 1.5 9.2 4.8 0.61 10.4 1.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5347) CTK3_C PF12350.8 CCH59163.1 - 2.2e-12 46.9 6.7 2.2e-11 43.8 7.1 2.4 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 CCH59163.1 - 1.3e-05 25.2 4.3 6.1e-05 23.0 4.3 2.1 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 Sp38 PF07354.12 CCH59163.1 - 0.13 11.7 0.3 0.26 10.7 0.1 1.6 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) TPK_catalytic PF04263.16 CCH59163.1 - 0.21 11.6 3.8 6.7 6.8 0.0 2.6 2 1 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain ubiquitin PF00240.23 CCH59165.1 - 1.5e-16 59.9 0.4 3.1e-16 58.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCH59165.1 - 1.2e-07 31.5 0.7 2.3e-07 30.5 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CCH59165.1 - 0.00013 22.0 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCH59165.1 - 0.00076 19.8 1.3 0.0011 19.2 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCH59165.1 - 0.031 14.2 0.0 0.089 12.7 0.0 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CCH59165.1 - 0.058 13.9 0.1 0.25 11.8 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain PGM_PMM_I PF02878.16 CCH59166.1 - 4e-37 127.0 0.0 7.1e-37 126.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CCH59166.1 - 3.9e-21 75.6 0.0 1e-20 74.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CCH59166.1 - 2.4e-13 50.3 0.0 4.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CCH59166.1 - 1.7e-07 31.3 0.0 4.7e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain S-methyl_trans PF02574.16 CCH59167.1 - 2.9e-58 197.8 0.0 3.4e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Anp1 PF03452.14 CCH59168.1 - 2.2e-121 404.3 0.0 3.3e-121 403.7 0.0 1.3 1 0 0 1 1 1 1 Anp1 Nab6_mRNP_bdg PF10567.9 CCH59169.1 - 2.9e-74 250.4 45.0 4.3e-61 207.1 12.3 6.0 6 1 1 7 7 7 3 RNA-recognition motif RRM PF10378.9 CCH59169.1 - 2.4e-17 62.4 8.4 2.4e-17 62.4 8.4 3.6 2 0 0 2 2 2 1 Putative RRM domain RRM_1 PF00076.22 CCH59169.1 - 8.8e-08 31.9 1.2 0.15 11.9 0.1 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5588 PF17826.1 CCH59169.1 - 0.03 13.2 1.8 0.072 12.0 1.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5588) DrrA_P4M PF14860.6 CCH59170.1 - 0.76 9.7 5.7 1.5 8.7 1.2 2.5 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain PIG-L PF02585.17 CCH59171.1 - 1.5e-13 51.5 0.0 2.4e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 CCH59172.1 - 1.3e-13 50.8 7.9 1.8e-13 50.3 1.1 3.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression RPT PF13446.6 CCH59172.1 - 0.02 14.8 0.5 0.52 10.3 0.2 3.0 2 0 0 2 2 2 0 A repeated domain in UCH-protein PPR PF01535.20 CCH59172.1 - 0.045 14.0 0.0 14 6.2 0.0 3.5 3 0 0 3 3 3 0 PPR repeat Glyco_hydro_76 PF03663.14 CCH59173.1 - 2.7e-154 514.1 17.8 3.1e-154 513.9 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ChAPs PF09295.10 CCH59174.1 - 6.1e-173 575.3 2.1 8.6e-173 574.9 2.1 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CCH59174.1 - 2.5e-05 24.0 2.0 0.084 13.0 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH59174.1 - 0.00024 21.6 0.1 0.022 15.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCH59174.1 - 0.0015 19.0 0.1 52 4.8 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH59174.1 - 0.0026 17.9 2.0 0.48 10.7 0.4 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CCH59174.1 - 0.0035 17.1 0.2 4.5 7.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59174.1 - 0.0063 16.6 0.4 0.14 12.4 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCH59174.1 - 0.045 13.5 0.2 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 TPR repeat HSBP1 PF06825.12 CCH59174.1 - 0.05 13.5 2.0 0.2 11.5 2.0 2.0 1 0 0 1 1 1 0 Heat shock factor binding protein 1 TPR_16 PF13432.6 CCH59174.1 - 0.069 13.8 0.1 5.6 7.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH59174.1 - 0.11 12.6 0.2 7.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59174.1 - 0.14 12.5 0.3 3 8.2 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ASD2 PF08687.11 CCH59174.1 - 7.4 6.0 13.8 0.47 10.0 7.8 1.9 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 RNA_pol_Rpc4 PF05132.14 CCH59174.1 - 9.1 6.7 6.7 39 4.6 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 TFIID-31kDa PF02291.15 CCH59175.1 - 8.1e-49 164.7 0.0 1.1e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Secretin_N_2 PF07655.13 CCH59175.1 - 0.0088 16.6 5.8 0.8 10.3 1.5 2.1 2 0 0 2 2 2 2 Secretin N-terminal domain Acyltransferase PF01553.21 CCH59176.1 - 0.0014 18.3 0.2 0.011 15.4 0.1 2.5 1 1 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CCH59176.1 - 0.025 14.7 0.0 0.077 13.1 0.0 1.9 1 0 0 1 1 1 0 Acyltransferase C-terminus GSH_synthase PF03199.15 CCH59176.1 - 0.82 10.1 3.8 0.36 11.3 0.2 2.3 3 0 0 3 3 3 0 Eukaryotic glutathione synthase SWIB PF02201.18 CCH59177.1 - 3.2e-27 94.2 0.4 7.1e-27 93.1 0.4 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CCH59177.1 - 7.5e-11 41.8 2.3 3.7e-10 39.6 0.1 2.7 3 0 0 3 3 3 1 DEK C terminal domain VPS11_C PF12451.8 CCH59178.1 - 1.4e-12 47.6 0.6 8.5e-12 45.1 0.1 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CCH59178.1 - 6.4e-07 29.3 5.8 1.7e-06 28.0 5.8 1.8 1 1 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 CCH59178.1 - 0.00045 20.1 7.1 0.00045 20.1 7.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CCH59178.1 - 0.00088 19.2 4.6 0.0028 17.6 4.6 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCH59178.1 - 0.0021 17.8 6.8 0.0052 16.6 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCH59178.1 - 0.0083 16.2 1.0 0.02 15.0 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCH59178.1 - 0.012 15.9 3.9 0.038 14.3 3.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CCH59178.1 - 0.014 15.0 2.6 0.028 14.0 2.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 CCH59178.1 - 0.016 15.4 4.1 1.8 8.7 0.1 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-RING_2 PF13639.6 CCH59178.1 - 0.033 14.5 6.5 0.078 13.3 6.5 1.7 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 CCH59178.1 - 0.13 12.2 10.8 0.015 15.2 4.7 2.4 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.6 CCH59178.1 - 0.29 11.3 9.8 0.041 14.1 5.4 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.6 CCH59178.1 - 0.61 10.4 7.4 5.4 7.3 0.2 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4 PF00097.25 CCH59178.1 - 3.1 7.7 12.0 0.32 10.9 7.2 2.0 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCH59178.1 - 5.1 6.9 9.6 1.8 8.4 5.9 2.3 2 0 0 2 2 2 0 RING-like zinc finger PHD_4 PF16866.5 CCH59178.1 - 6.5 6.9 5.7 0.83 9.8 0.4 2.3 3 0 0 3 3 1 0 PHD-finger Mpv17_PMP22 PF04117.12 CCH59179.1 - 2.4e-13 50.1 3.6 2.4e-13 50.1 3.6 2.3 2 1 1 3 3 3 1 Mpv17 / PMP22 family RrnaAD PF00398.20 CCH59180.1 - 4.4e-32 111.2 0.0 5.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase AMMECR1 PF01871.17 CCH59181.1 - 1.1e-37 129.2 0.0 1.3e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.25 CCH59182.1 - 5.1e-12 45.7 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCH59182.1 - 0.00044 20.2 0.0 0.0007 19.6 0.0 1.3 1 0 0 1 1 1 1 KR domain FSH1 PF03959.13 CCH59183.1 - 4.8e-56 189.8 0.0 6.1e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCH59183.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CCH59183.1 - 0.0047 16.2 0.0 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF3914 PF13053.6 CCH59183.1 - 0.011 16.0 1.5 0.022 15.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) MFS_1 PF07690.16 CCH59184.1 - 0.044 12.7 42.6 0.0065 15.4 33.8 3.0 1 1 2 3 3 3 0 Major Facilitator Superfamily GHMP_kinases_N PF00288.26 CCH59186.1 - 4.8e-15 55.6 1.5 9e-15 54.7 0.8 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCH59186.1 - 0.00057 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF3535 PF12054.8 CCH59186.1 - 0.038 13.3 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) TRAPPC10 PF12584.8 CCH59188.1 - 1.8e-08 34.2 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF3119 PF11317.8 CCH59188.1 - 0.00026 21.3 0.3 0.00026 21.3 0.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3119) Gryzun-like PF12742.7 CCH59188.1 - 0.014 15.4 0.1 0.038 14.0 0.1 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.8 CCH59188.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_2 PF07719.17 CCH59188.1 - 0.049 13.8 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_helicase PF00910.22 CCH59188.1 - 0.14 12.6 4.4 1.2 9.5 0.2 3.3 2 1 1 3 3 3 0 RNA helicase NYD-SP28_assoc PF14775.6 CCH59188.1 - 1 9.5 6.9 3.5 7.8 1.3 2.9 2 0 0 2 2 2 0 Sperm tail C-terminal domain HEM4 PF02602.15 CCH59189.1 - 3.1e-37 128.2 0.0 3.5e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1506 PF07405.11 CCH59189.1 - 0.072 13.3 1.4 5.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) Flavodoxin_1 PF00258.25 CCH59189.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin DnaJ_C PF01556.18 CCH59190.1 - 1.6e-23 83.4 0.0 2.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCH59190.1 - 6.8e-23 80.6 7.7 1.2e-22 79.8 7.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCH59190.1 - 1.6e-14 54.0 15.3 2.4e-14 53.4 15.3 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CCH59190.1 - 3.1e-05 23.9 7.0 0.00027 20.8 1.3 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CCH59190.1 - 1.4 9.0 8.8 9.1 6.4 9.3 2.0 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 CCH59190.1 - 4.2 7.4 9.3 2.7 8.0 1.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CAF20 PF17052.5 CCH59191.1 - 1.8e-50 171.2 5.9 2.1e-50 171.0 5.9 1.0 1 0 0 1 1 1 1 Cap associated factor Myb_DNA-binding PF00249.31 CCH59192.1 - 4.3e-19 68.4 1.9 6.6e-13 48.6 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH59192.1 - 3.8e-17 62.3 0.7 2.3e-12 47.0 0.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CCH59192.1 - 0.00011 21.8 2.4 0.00011 21.8 2.4 2.6 2 0 0 2 2 2 1 pre-mRNA splicing factor component SLIDE PF09111.10 CCH59192.1 - 0.0011 18.9 4.4 0.047 13.7 0.0 3.8 4 2 1 5 5 5 1 SLIDE Fib_alpha PF08702.10 CCH59192.1 - 0.17 12.1 5.2 0.49 10.6 5.2 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family gag_pre-integrs PF13976.6 CCH59193.1 - 0.031 14.1 0.2 0.26 11.2 0.0 2.8 2 0 0 2 2 2 0 GAG-pre-integrase domain Tubulin_3 PF14881.6 CCH59194.1 - 6.7e-26 91.1 2.0 7.3e-26 90.9 0.1 2.0 2 1 1 3 3 3 1 Tubulin domain Misat_Tub_SegII PF10644.9 CCH59194.1 - 2.9e-20 72.7 0.6 2.9e-20 72.7 0.6 2.3 2 1 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CCH59194.1 - 0.0031 17.7 0.2 0.62 10.2 0.0 2.9 3 1 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain MFS_1 PF07690.16 CCH59195.1 - 5.5e-09 35.4 4.0 6.6e-09 35.1 4.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2513 PF10711.9 CCH59195.1 - 0.14 12.4 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) N2227 PF07942.12 CCH59196.1 - 4.8e-63 212.9 0.4 9.9e-63 211.9 0.4 1.5 1 0 0 1 1 1 1 N2227-like protein HAD_2 PF13419.6 CCH59196.1 - 0.23 11.5 1.9 4.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 CCH59197.1 - 1.2e-23 82.9 15.0 2.3e-07 31.4 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 CCH59197.1 - 2.6e-23 82.3 0.4 6.5e-23 81.0 0.4 1.7 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CCH59197.1 - 7.4e-07 28.2 9.3 0.015 14.0 0.3 3.3 1 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCH59197.1 - 0.0015 18.8 0.1 0.016 15.5 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCH59197.1 - 0.0057 16.0 1.2 0.17 11.2 1.2 2.9 1 1 0 1 1 1 1 WD40-like domain V_ATPase_I PF01496.19 CCH59198.1 - 0 1016.2 10.6 0 1016.0 10.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FA_desaturase PF00487.24 CCH59198.1 - 0.0092 15.8 0.0 0.063 13.1 0.1 2.2 2 0 0 2 2 2 1 Fatty acid desaturase Baculo_PEP_C PF04513.12 CCH59198.1 - 0.085 12.9 0.2 0.085 12.9 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GIT_CC PF16559.5 CCH59198.1 - 8 6.4 7.4 0.31 10.9 0.2 2.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pkinase PF00069.25 CCH59199.1 - 1.6e-47 162.1 0.8 7.7e-43 146.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59199.1 - 2.3e-20 73.0 0.0 6.3e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59199.1 - 0.00091 18.6 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TBCA PF02970.16 CCH59201.1 - 3.9e-25 88.0 12.9 4.7e-25 87.7 12.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Cytochrom_C_2 PF01322.20 CCH59201.1 - 0.014 16.3 0.2 0.018 15.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C' FapA PF03961.13 CCH59201.1 - 0.067 11.8 9.3 0.073 11.7 9.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A YlqD PF11068.8 CCH59201.1 - 0.36 11.2 8.7 0.33 11.3 4.2 2.1 1 1 1 2 2 2 0 YlqD protein Csm1_N PF18504.1 CCH59201.1 - 1.2 9.5 10.5 1.5 9.2 4.4 2.5 2 1 1 3 3 3 0 Csm1 N-terminal domain PdaC PF13739.6 CCH59201.1 - 1.5 9.8 7.7 0.51 11.4 3.8 1.9 1 1 1 2 2 2 0 Deacetylase PdaC LMBR1 PF04791.16 CCH59202.1 - 0.53 9.1 5.5 1 8.2 5.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein MitMem_reg PF13012.6 CCH59203.1 - 1.2e-33 115.9 1.1 2.5e-33 114.8 1.1 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CCH59203.1 - 5.4e-32 110.2 0.5 9.5e-32 109.4 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APG12 PF04110.13 CCH59203.1 - 0.35 11.3 3.0 0.62 10.5 0.3 2.6 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 HIT PF01230.23 CCH59204.1 - 1.7e-16 60.8 0.1 4.1e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCH59204.1 - 2.1e-13 50.7 2.5 4.4e-12 46.5 2.5 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 CCH59204.1 - 5.5e-13 49.1 4.1 1.4e-12 47.9 4.1 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger KOW PF00467.29 CCH59205.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 KOW motif EF-hand_7 PF13499.6 CCH59206.1 - 2.1e-25 89.0 11.7 1e-14 54.7 2.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCH59206.1 - 1.6e-22 77.3 15.3 1.7e-07 30.3 1.9 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CCH59206.1 - 3.3e-19 67.1 11.2 2e-05 24.2 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CCH59206.1 - 2.4e-13 49.7 14.2 6.3e-10 38.8 0.9 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CCH59206.1 - 2.5e-11 42.5 8.1 0.00099 18.5 1.6 3.8 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CCH59206.1 - 0.00013 21.9 3.5 0.039 13.9 0.3 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CCH59206.1 - 0.00014 22.1 0.4 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CCH59206.1 - 0.002 18.3 2.8 1.2 9.3 0.3 2.4 2 0 0 2 2 2 2 Dockerin type I domain SPARC_Ca_bdg PF10591.9 CCH59206.1 - 0.002 18.4 2.3 0.79 10.1 0.2 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CCH59206.1 - 0.0055 16.6 0.5 0.49 10.3 0.0 3.1 1 1 3 4 4 4 1 Caleosin related protein FGAR-AT_linker PF18072.1 CCH59206.1 - 0.013 16.1 0.1 10 6.8 0.1 2.7 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF1296 PF06972.11 CCH59206.1 - 0.069 13.3 2.6 17 5.6 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1296) VASP_tetra PF08776.11 CCH59206.1 - 0.1 12.2 0.4 0.1 12.2 0.4 2.2 3 0 0 3 3 3 0 VASP tetramerisation domain EF-hand_11 PF08976.11 CCH59206.1 - 0.14 13.1 0.1 0.27 12.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain DED PF01335.21 CCH59206.1 - 0.22 11.8 3.6 2.4 8.5 0.1 3.1 3 1 0 3 3 3 0 Death effector domain PhetRS_B1 PF18262.1 CCH59206.1 - 0.31 11.3 3.3 0.18 12.0 0.5 2.1 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain CAP_GLY PF01302.25 CCH59207.1 - 1.3e-21 76.4 0.5 2.1e-21 75.7 0.5 1.3 1 0 0 1 1 1 1 CAP-Gly domain BHD_1 PF10403.9 CCH59207.1 - 0.48 10.3 2.5 28 4.7 0.0 2.9 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 YtxH PF12732.7 CCH59207.1 - 1.3 9.6 5.5 41 4.8 0.2 3.8 2 2 0 2 2 2 0 YtxH-like protein Fez1 PF06818.15 CCH59207.1 - 1.3 9.4 30.1 0.37 11.2 11.5 2.6 2 0 0 2 2 2 0 Fez1 RPW8 PF05659.11 CCH59207.1 - 2.2 7.9 22.4 0.032 13.9 4.5 3.3 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PKcGMP_CC PF16808.5 CCH59207.1 - 3.5 7.5 10.4 0.075 12.9 1.0 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TFR_dimer PF04253.15 CCH59208.1 - 2.4e-30 105.1 0.0 4.8e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCH59208.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.15 CCH59208.1 - 0.0017 17.9 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Rad9_Rad53_bind PF08605.10 CCH59208.1 - 0.037 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Cyt-b5 PF00173.28 CCH59209.1 - 4.1e-11 42.9 0.0 7.5e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FNIP PF05725.12 CCH59210.1 - 0.4 10.9 7.6 3.4 7.9 0.2 3.3 3 0 0 3 3 3 0 FNIP Repeat RRM_9 PF18444.1 CCH59211.1 - 3.6e-26 90.8 2.0 5.4e-26 90.2 0.9 1.9 2 0 0 2 2 2 1 RNA recognition motif TAP_C PF03943.13 CCH59211.1 - 3.7e-13 48.9 0.4 1.1e-12 47.4 0.4 1.8 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 CCH59211.1 - 1.3e-08 34.6 0.9 2.5e-08 33.6 0.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 CCH59211.1 - 0.00053 20.6 0.3 0.0064 17.0 0.7 2.5 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain LRR_4 PF12799.7 CCH59211.1 - 0.0013 19.1 2.6 0.0013 19.1 2.6 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) PDH PF02153.17 CCH59211.1 - 0.053 12.5 0.2 0.09 11.8 0.2 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase DnaJ PF00226.31 CCH59212.1 - 5.9e-17 61.5 3.6 1.1e-16 60.6 0.3 2.7 2 0 0 2 2 2 1 DnaJ domain PRD1_DD PF11087.8 CCH59212.1 - 0.1 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 PRD1 phage membrane DNA delivery Afi1 PF07792.12 CCH59212.1 - 0.72 10.3 9.4 2.2 8.8 9.4 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Acetyltransf_1 PF00583.25 CCH59213.1 - 3.2e-14 53.2 0.1 3.9e-14 52.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCH59213.1 - 2.5e-12 47.0 0.2 3.4e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCH59213.1 - 4.9e-11 42.7 0.1 6.4e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCH59213.1 - 3.4e-07 30.1 0.0 5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CCH59213.1 - 2.3e-05 24.6 0.6 3e-05 24.2 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCH59213.1 - 0.019 14.5 0.7 0.032 13.7 0.6 1.6 1 1 1 2 2 2 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CCH59213.1 - 0.12 13.0 0.0 0.14 12.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5340 PF17275.2 CCH59214.1 - 0.11 12.7 1.3 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5340) ARA70 PF12489.8 CCH59214.1 - 0.3 11.3 3.9 0.77 10.0 3.9 1.7 1 0 0 1 1 1 0 Nuclear coactivator BST2 PF16716.5 CCH59214.1 - 0.77 10.4 6.1 2.6 8.7 6.1 1.9 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Tma16 PF11176.8 CCH59215.1 - 6.2e-50 168.9 4.8 7.5e-50 168.6 4.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 adh_short PF00106.25 CCH59217.1 - 8.6e-23 80.8 0.0 1.3e-10 41.1 0.0 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 CCH59217.1 - 2.5e-15 56.7 0.0 2.9e-10 40.1 0.0 3.0 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH59217.1 - 0.00024 21.1 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCH59217.1 - 0.00034 20.2 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CCH59217.1 - 0.044 13.2 0.3 0.29 10.5 0.3 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 CCH59217.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_1 PF00133.22 CCH59218.1 - 2.6e-44 151.5 0.1 4.9e-35 120.9 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCH59218.1 - 1.1e-16 60.6 0.2 1.8e-09 36.8 0.0 3.8 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCH59218.1 - 1.8e-12 47.5 0.0 5e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCH59218.1 - 9.4e-07 28.5 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pet20 PF08692.10 CCH59219.1 - 1.7e-10 41.7 12.9 2.6e-05 24.9 0.1 3.9 2 2 1 3 3 3 2 Mitochondrial protein Pet20 Type2_restr_D3 PF16902.5 CCH59221.1 - 0.44 10.5 2.8 2.4 8.1 0.2 2.5 1 1 0 2 2 2 0 Type-2 restriction enzyme D3 domain ATP-synt_8 PF00895.20 CCH59221.1 - 2.2 8.8 4.2 1.2 9.7 0.7 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 Asp PF00026.23 CCH59222.1 - 6.8e-106 354.2 0.0 8.4e-106 353.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH59222.1 - 1.7e-14 54.4 0.3 6e-12 46.1 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CCH59222.1 - 0.0024 17.6 0.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 CCH59222.1 - 0.0058 17.2 0.0 0.52 10.9 0.0 2.8 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Pkinase PF00069.25 CCH59223.1 - 2.2e-78 263.3 0.0 4.9e-78 262.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59223.1 - 8.3e-39 133.4 0.0 1.6e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCH59223.1 - 4.3e-26 91.0 1.1 1.5e-14 54.0 0.1 3.5 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.6 CCH59223.1 - 7.5e-13 48.4 0.0 6.9e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 CCH59223.1 - 5.5e-08 33.0 0.0 2.6e-05 24.4 0.0 3.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 CCH59223.1 - 4.3e-06 26.8 0.0 0.011 15.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCH59223.1 - 7.6e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 CCH59223.1 - 0.00021 21.5 2.9 5.3 7.3 0.0 4.3 4 0 0 4 4 4 2 FHA domain RIO1 PF01163.22 CCH59223.1 - 0.0023 17.5 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 RIO1 family RGS_DHEX PF18148.1 CCH59223.1 - 0.6 10.3 3.6 5.6 7.1 0.8 2.7 2 0 0 2 2 2 0 Regulator of G-protein signalling DHEX domain Mur_ligase_M PF08245.12 CCH59224.1 - 2.6e-05 24.3 0.3 0.017 15.2 0.0 2.9 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 CCH59224.1 - 0.009 16.2 0.0 0.033 14.4 0.0 2.0 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Pkinase PF00069.25 CCH59225.1 - 2.3e-65 220.6 0.0 4.1e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59225.1 - 1e-35 123.3 0.0 1.7e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59225.1 - 4.5e-06 26.2 0.0 7.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SGT1 PF07093.11 CCH59226.1 - 5.5e-14 51.5 0.2 7.2e-14 51.2 0.2 1.1 1 0 0 1 1 1 1 SGT1 protein Methyltransf_23 PF13489.6 CCH59227.1 - 1.8e-14 53.9 0.0 3.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH59227.1 - 8.4e-12 45.1 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH59227.1 - 1.2e-11 45.2 0.3 3.8e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH59227.1 - 6.4e-11 42.8 0.0 1.4e-10 41.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH59227.1 - 4.7e-09 36.8 0.0 1.4e-08 35.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 CCH59227.1 - 2e-05 24.1 1.3 5.3e-05 22.8 0.1 2.3 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.14 CCH59227.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CCH59227.1 - 0.036 14.0 0.1 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF1694 PF07997.11 CCH59227.1 - 0.069 13.2 0.1 0.27 11.3 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) ACPS PF01648.20 CCH59228.1 - 3.9e-12 46.3 0.0 5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF1749 PF08538.10 CCH59229.1 - 1.3e-98 329.8 0.0 1.5e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CCH59229.1 - 1.6e-07 30.8 0.0 1.5e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CCH59229.1 - 2.4e-06 27.2 0.0 0.00078 19.0 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CCH59229.1 - 6.6e-05 22.7 0.1 0.0011 18.6 0.1 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 CCH59229.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 CCH59229.1 - 0.024 14.2 0.1 0.17 11.5 0.1 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ndr PF03096.14 CCH59229.1 - 0.053 12.2 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF2974 PF11187.8 CCH59229.1 - 0.061 12.9 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 CCH59229.1 - 0.074 12.6 0.0 7.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CCH59229.1 - 0.093 13.3 0.0 0.099 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 CCH59229.1 - 0.16 11.5 0.2 0.55 9.7 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) COesterase PF00135.28 CCH59229.1 - 0.17 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Oxysterol_BP PF01237.18 CCH59231.1 - 4.5e-57 193.6 1.5 9.8e-57 192.5 1.5 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein UPF0228 PF05727.11 CCH59231.1 - 0.048 13.5 1.7 0.97 9.3 0.4 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0228) DHFR_1 PF00186.19 CCH59232.1 - 1.7e-23 83.1 0.0 3.3e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase RibD_C PF01872.17 CCH59232.1 - 0.032 14.0 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain POC3_POC4 PF10448.9 CCH59233.1 - 4.7e-10 39.6 0.3 5.2e-10 39.5 0.3 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 PAC4 PF16093.5 CCH59233.1 - 3.6e-06 27.1 0.0 5.9e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Ribosomal_L35Ae PF01247.18 CCH59234.1 - 2.4e-42 143.0 0.6 2.7e-42 142.9 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CCH59234.1 - 0.0029 17.8 0.0 0.51 10.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.25 CCH59235.1 - 2.5e-65 220.5 0.0 4.2e-65 219.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59235.1 - 1.8e-37 129.0 0.0 2.9e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59235.1 - 1.8e-07 30.8 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCH59235.1 - 0.11 11.8 0.3 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH59235.1 - 0.22 11.4 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GrpE PF01025.19 CCH59236.1 - 6e-48 162.6 10.7 1.1e-47 161.8 10.7 1.4 1 1 0 1 1 1 1 GrpE Uds1 PF15456.6 CCH59236.1 - 0.00024 21.3 2.4 0.0004 20.5 2.4 1.4 1 0 0 1 1 1 1 Up-regulated During Septation TACC_C PF05010.14 CCH59236.1 - 0.0006 19.6 15.5 0.01 15.6 0.4 2.1 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PKcGMP_CC PF16808.5 CCH59236.1 - 0.12 12.2 6.0 0.28 11.1 5.1 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF5352 PF17303.2 CCH59236.1 - 0.13 12.1 2.3 0.19 11.5 2.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5352) Atg14 PF10186.9 CCH59236.1 - 0.26 10.3 6.6 0.3 10.1 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup54 PF13874.6 CCH59236.1 - 0.27 11.3 5.8 0.42 10.7 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF641 PF04859.12 CCH59236.1 - 0.76 10.1 10.9 0.5 10.7 8.5 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 CCH59236.1 - 2.4 7.6 14.3 3 7.2 14.0 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 UPF0242 PF06785.11 CCH59236.1 - 9 6.4 19.3 3.8 7.6 16.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 CCH59237.1 - 9.6e-72 241.5 0.0 2.1e-71 240.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59237.1 - 1.9e-36 125.7 0.0 3.8e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59237.1 - 3.3e-07 29.9 0.0 6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CCH59237.1 - 0.00088 19.0 0.1 0.83 9.2 0.0 2.5 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCH59237.1 - 0.0034 16.2 0.0 0.0034 16.2 0.0 2.7 3 1 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 CCH59237.1 - 0.032 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 CCH59238.1 - 8e-06 26.5 9.4 0.011 16.5 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Mito_carr PF00153.27 CCH59240.1 - 2e-62 207.2 0.6 3.5e-23 81.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl_transf_1 PF00698.21 CCH59241.1 - 3.8e-07 29.9 0.0 1.7e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Acyl transferase domain DPPIV_N PF00930.21 CCH59242.1 - 4.7e-91 305.2 7.6 6.7e-91 304.7 7.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CCH59242.1 - 3.7e-51 173.6 0.2 6.4e-51 172.8 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CCH59242.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Orf78 PF06024.12 CCH59242.1 - 0.022 15.1 0.2 0.046 14.0 0.2 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Abhydrolase_6 PF12697.7 CCH59242.1 - 0.087 13.4 0.0 1.2 9.7 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCH59242.1 - 0.12 11.6 0.0 8.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RseA_N PF03872.13 CCH59243.1 - 0.13 12.8 0.2 0.27 11.7 0.2 1.5 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain Pro-NT_NN PF07421.11 CCH59243.1 - 0.38 11.0 3.1 6.1 7.1 1.3 2.1 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor YEATS PF03366.16 CCH59244.1 - 2.5e-21 75.4 0.0 4.1e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CCH59244.1 - 1.6e-06 28.2 0.1 2.7e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation WD40 PF00400.32 CCH59245.1 - 5.4e-26 90.3 25.7 0.00016 22.4 0.6 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59245.1 - 1.5e-08 34.8 0.4 1.1 9.6 0.0 4.8 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain TRF PF08558.10 CCH59246.1 - 6.1e-50 170.1 5.4 1.1e-49 169.3 5.4 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CCH59246.1 - 1.1e-05 25.5 0.2 3.1e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Linker_histone PF00538.19 CCH59247.1 - 8.3e-50 167.1 10.6 4.9e-25 87.7 0.4 2.9 3 1 0 3 3 3 2 linker histone H1 and H5 family DUF1911 PF08929.10 CCH59247.1 - 0.0017 19.1 3.8 0.61 10.9 0.4 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF1911) Pre-PUA PF17832.1 CCH59247.1 - 0.0064 17.2 9.0 0.2 12.4 0.1 3.3 3 1 0 3 3 3 2 Pre-PUA-like domain BrkDBD PF09607.10 CCH59247.1 - 0.035 13.9 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain FliE PF02049.18 CCH59247.1 - 2.1 8.6 10.6 2 8.6 0.2 3.8 2 2 2 4 4 4 0 Flagellar hook-basal body complex protein FliE Med13_C PF06333.12 CCH59247.1 - 3.6 6.8 14.4 0.8 8.9 10.4 1.7 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain Dynamin_N PF00350.23 CCH59248.1 - 2.4e-42 144.8 0.1 2.4e-42 144.8 0.1 3.4 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 CCH59248.1 - 1.8e-05 24.8 0.1 0.00019 21.5 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 CCH59248.1 - 5.1e-05 22.6 9.3 0.0072 15.6 0.0 3.6 2 1 0 2 2 2 1 Dynamin central region AAA_16 PF13191.6 CCH59248.1 - 0.046 14.1 0.3 0.19 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CCH59248.1 - 0.078 13.2 0.0 0.35 11.1 0.0 2.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase CENP-B_dimeris PF09026.10 CCH59248.1 - 0.44 11.0 9.1 1.1 9.7 9.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_N PF01194.17 CCH59249.1 - 6.4e-30 103.2 0.5 7.3e-30 103.1 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CCH59249.1 - 0.061 13.6 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.32 CCH59250.1 - 0.00021 22.0 1.9 0.0088 16.9 0.1 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat NAPRTase PF04095.16 CCH59251.1 - 1.5e-73 247.4 0.1 1.9e-73 247.0 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CCH59251.1 - 1.2e-32 112.9 2.2 2.7e-32 111.8 2.2 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Y_phosphatase PF00102.27 CCH59252.1 - 2.4e-54 184.4 15.1 1.7e-52 178.3 2.6 3.1 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CCH59252.1 - 0.0032 17.5 0.0 0.0065 16.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CCH59252.1 - 0.12 12.2 0.0 0.12 12.2 0.0 4.0 4 1 0 4 4 4 0 Dual specificity phosphatase, catalytic domain RNA_pol_Rpb2_6 PF00562.28 CCH59253.1 - 2.1e-125 418.9 0.2 2.1e-125 418.9 0.2 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCH59253.1 - 1.4e-57 194.5 0.9 2e-57 194.0 0.9 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCH59253.1 - 2e-42 145.0 3.1 6.8e-42 143.3 3.4 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCH59253.1 - 1.4e-33 115.1 0.2 4.4e-33 113.5 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCH59253.1 - 3.7e-25 88.0 0.1 1.2e-24 86.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCH59253.1 - 2.1e-18 66.3 0.0 4.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCH59253.1 - 1.4e-10 41.6 0.3 5e-10 39.8 0.3 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Glyco_hydro_72 PF03198.14 CCH59253.1 - 0.086 12.1 0.2 0.62 9.2 0.0 2.0 2 0 0 2 2 2 0 Glucanosyltransferase Phos_pyr_kin PF08543.12 CCH59254.1 - 2e-74 250.1 1.9 2.1e-74 250.0 1.2 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CCH59254.1 - 2.8e-49 167.8 1.7 5.2e-49 166.9 1.7 1.5 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CCH59254.1 - 9.5e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CCH59255.1 - 1.1e-61 208.4 0.1 1.5e-61 207.9 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CCH59255.1 - 2.8e-48 164.5 0.3 4e-48 164.0 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CCH59255.1 - 3.5e-06 26.6 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Noc2 PF03715.13 CCH59256.1 - 1.4e-115 385.7 7.9 1.4e-115 385.7 7.9 2.5 3 0 0 3 3 3 1 Noc2p family Nop14 PF04147.12 CCH59256.1 - 1.5e-05 23.4 19.1 6.6e-05 21.3 16.7 3.2 3 0 0 3 3 3 2 Nop14-like family RsbRD_N PF14361.6 CCH59256.1 - 0.0063 17.2 0.1 0.13 13.0 0.0 3.2 2 0 0 2 2 2 1 RsbT co-antagonist protein rsbRD N-terminal domain Tir_receptor_N PF07490.11 CCH59256.1 - 0.041 13.7 0.3 0.085 12.7 0.3 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus SPT16 PF08644.11 CCH59256.1 - 1.9 8.7 14.5 0.22 11.7 0.8 3.3 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) MMR_HSR1 PF01926.23 CCH59257.1 - 6.1e-09 36.0 0.2 1.1e-07 31.9 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH59257.1 - 0.00078 19.0 0.4 0.1 12.2 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCH59257.1 - 0.00087 19.2 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 CCH59257.1 - 0.0014 18.7 0.1 0.052 13.6 0.0 2.8 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 CCH59257.1 - 0.0094 16.2 0.1 0.032 14.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CCH59257.1 - 0.034 13.7 0.1 0.1 12.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.22 CCH59257.1 - 0.066 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 CCH59257.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter zinc_ribbon_15 PF17032.5 CCH59257.1 - 3.9 8.3 6.6 10 7.0 2.4 2.9 3 1 1 4 4 4 0 zinc-ribbon family DEAD PF00270.29 CCH59258.1 - 2.7e-49 167.3 0.0 1.1e-48 165.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59258.1 - 6.7e-33 113.4 0.0 1.9e-32 111.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59258.1 - 0.0055 16.7 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCH59258.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCH59258.1 - 0.04 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CCH59258.1 - 0.15 10.8 0.0 0.41 9.4 0.0 1.6 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Mit_ribos_Mrp51 PF11709.8 CCH59259.1 - 2.1e-49 169.1 3.9 1.9e-25 90.3 0.3 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit SpoU_methylase PF00588.19 CCH59260.1 - 2.1e-26 92.8 0.1 1.5e-23 83.5 0.0 2.9 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CCH59260.1 - 4.6e-11 42.8 0.1 1e-10 41.8 0.1 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding NUDIX PF00293.28 CCH59261.1 - 3e-23 82.3 0.0 5.4e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Peptidase_C14 PF00656.22 CCH59263.1 - 1.3e-65 221.8 0.1 1.7e-65 221.4 0.1 1.1 1 0 0 1 1 1 1 Caspase domain TAL_effector PF03377.13 CCH59263.1 - 0.0024 18.2 0.0 0.78 10.1 0.0 2.5 2 0 0 2 2 2 2 TAL effector repeat LIAS_N PF16881.5 CCH59264.1 - 4.4e-22 78.5 0.1 9.5e-22 77.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CCH59264.1 - 1.5e-14 54.7 0.0 2.5e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 CCH59264.1 - 0.076 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Phyto-Amp PF15438.6 CCH59264.1 - 0.15 11.9 0.2 0.26 11.1 0.2 1.4 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma RhoGAP PF00620.27 CCH59265.1 - 8.2e-26 90.7 0.1 8.2e-26 90.7 0.1 2.7 4 0 0 4 4 4 1 RhoGAP domain PH PF00169.29 CCH59265.1 - 4.1e-06 27.2 3.2 7.6e-06 26.4 0.2 2.7 2 0 0 2 2 2 1 PH domain PX PF00787.24 CCH59265.1 - 2.6e-05 24.2 0.9 8.8e-05 22.5 0.9 2.0 1 0 0 1 1 1 1 PX domain Arginase PF00491.21 CCH59266.1 - 8.3e-73 245.3 0.0 9.6e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family FKBP_N_2 PF18023.1 CCH59266.1 - 0.051 13.7 0.0 0.23 11.5 0.0 1.9 2 0 0 2 2 2 0 BDBT FKBP like N-terminal GDPD PF03009.17 CCH59267.1 - 1.2e-80 271.0 0.1 3.3e-80 269.5 0.1 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CCH59267.1 - 7.5e-27 93.7 10.6 4e-13 49.8 1.8 4.7 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCH59267.1 - 1.2e-18 66.9 1.4 8.3e-06 26.0 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH59267.1 - 9.2e-16 58.0 1.6 1.1e-06 29.0 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 CCH59267.1 - 1.8e-15 57.7 17.9 8.3e-15 55.6 11.6 3.2 2 1 0 2 2 2 1 SPX domain Ank_3 PF13606.6 CCH59267.1 - 4.1e-12 45.2 5.3 0.61 10.8 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 CCH59267.1 - 2.9e-08 33.8 4.2 0.5 10.9 0.0 6.1 5 1 0 5 5 5 3 Ankyrin repeat ABC1 PF03109.16 CCH59268.1 - 1.2e-20 73.9 0.0 4.6e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 ABC1 family tRNA-synt_1 PF00133.22 CCH59270.1 - 0.088 11.0 0.1 0.1 10.8 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Pex24p PF06398.11 CCH59271.1 - 5.9e-25 88.0 31.7 2.1e-13 50.0 19.9 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin HSP70 PF00012.20 CCH59272.1 - 4.6e-181 603.0 2.2 1.1e-180 601.7 2.2 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH59272.1 - 2.9e-09 36.2 0.0 1.1e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CCH59272.1 - 0.00076 19.9 0.1 0.013 15.9 0.1 2.8 2 0 0 2 2 2 1 Cell division protein FtsA Trans_reg_C PF00486.28 CCH59272.1 - 0.11 12.6 0.3 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal Sec66 PF09802.9 CCH59273.1 - 5.5e-70 234.6 2.8 7.1e-70 234.2 2.8 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 TMEM154 PF15102.6 CCH59273.1 - 0.017 15.1 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family GYF PF02213.16 CCH59274.1 - 2.6e-13 49.4 0.2 5.4e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 GYF domain UMP1 PF05348.11 CCH59275.1 - 4.2e-40 136.6 0.1 6.5e-40 136.0 0.1 1.3 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.32 CCH59276.1 - 1.2e-26 92.4 13.4 1e-07 32.5 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59276.1 - 1.9e-16 60.1 0.1 1.7e-06 28.2 0.1 5.8 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH59276.1 - 5.5e-08 32.9 0.2 2.7e-05 24.1 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 CCH59276.1 - 5.7e-06 25.9 1.9 0.00086 18.7 0.2 3.5 3 1 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 CCH59276.1 - 0.0028 17.6 0.5 2.1 8.4 0.0 3.8 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 CCH59276.1 - 0.0028 16.8 0.0 0.0059 15.7 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region Itfg2 PF15907.5 CCH59276.1 - 0.035 13.1 0.2 0.13 11.3 0.0 2.1 2 1 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Nup160 PF11715.8 CCH59276.1 - 0.041 12.5 0.2 0.081 11.5 0.0 1.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 tRNA-synt_2 PF00152.20 CCH59277.1 - 1.2e-90 303.8 0.2 1.6e-90 303.4 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCH59277.1 - 2.8e-05 24.0 0.4 7.3e-05 22.7 0.4 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCH59277.1 - 0.0032 17.0 0.0 0.21 11.1 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 CCH59277.1 - 0.051 13.6 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) GCR1_C PF12550.8 CCH59277.1 - 0.061 13.6 3.2 0.28 11.5 0.2 2.7 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Pantoate_transf PF02548.15 CCH59278.1 - 3.1e-94 315.2 0.0 3.6e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CCH59278.1 - 0.00016 21.2 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PEP_hydrolase PF09370.10 CCH59278.1 - 0.17 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Lactamase_B_2 PF12706.7 CCH59279.1 - 5.8e-27 94.5 0.0 8.5e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCH59279.1 - 8.3e-09 35.5 0.1 1.9e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CCH59279.1 - 0.0054 16.8 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PAXNEB PF05625.11 CCH59280.1 - 2.9e-95 319.5 2.5 3.5e-95 319.3 2.5 1.1 1 0 0 1 1 1 1 PAXNEB protein Lipoprotein_3 PF00938.17 CCH59280.1 - 0.016 15.4 0.2 0.13 12.4 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein K_trans PF02705.16 CCH59281.1 - 0.061 11.8 0.0 0.082 11.4 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter Abhydrolase_1 PF00561.20 CCH59282.1 - 3.2e-18 66.3 0.0 1.2e-17 64.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH59282.1 - 3.2e-07 29.9 0.0 2.3e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CCH59282.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase NOG1_N PF17835.1 CCH59283.1 - 2.3e-49 167.4 0.1 2.3e-49 167.4 0.1 2.4 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CCH59283.1 - 3.8e-26 90.8 5.1 3.8e-26 90.8 5.1 2.8 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 CCH59283.1 - 7.1e-26 89.8 0.2 2.4e-25 88.1 0.2 2.0 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CCH59283.1 - 4.4e-16 59.0 0.0 1.2e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH59283.1 - 1.6e-07 31.0 0.0 3.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCH59283.1 - 0.00069 19.6 0.1 0.66 9.9 0.1 3.3 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 CCH59283.1 - 0.024 15.0 0.0 0.14 12.5 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain NAGidase PF07555.13 CCH59283.1 - 0.056 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Roc PF08477.13 CCH59283.1 - 0.13 12.5 0.0 0.44 10.8 0.0 2.0 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PTH2 PF01981.16 CCH59283.1 - 0.43 10.9 1.6 12 6.2 0.2 2.5 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 Dynamin_N PF00350.23 CCH59283.1 - 0.49 10.4 4.6 6.4 6.8 0.0 3.2 3 1 1 4 4 4 0 Dynamin family MFS_1 PF07690.16 CCH59284.1 - 4.2e-50 170.6 26.8 7.7e-48 163.2 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH59284.1 - 9.4e-21 74.2 27.1 1.8e-17 63.4 4.9 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 CCH59284.1 - 0.0012 18.2 5.3 0.0012 18.2 5.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 CCH59284.1 - 0.0043 15.5 15.1 0.086 11.2 7.8 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector TauE PF01925.19 CCH59284.1 - 0.0073 16.0 30.6 0.27 10.8 0.0 4.2 3 1 1 4 4 4 2 Sulfite exporter TauE/SafE Ribosomal_S6e PF01092.19 CCH59285.1 - 7e-55 184.4 0.5 1.4e-54 183.4 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Caps_synth_GfcC PF06251.11 CCH59285.1 - 0.13 11.9 1.5 0.18 11.4 1.5 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC SRF-TF PF00319.18 CCH59286.1 - 1.5e-20 72.4 0.0 2.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PI3K_1B_p101 PF10486.9 CCH59286.1 - 0.17 9.6 1.6 0.21 9.3 1.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ceramidase PF05875.12 CCH59287.1 - 4.1e-84 282.1 24.6 5e-84 281.8 24.6 1.0 1 0 0 1 1 1 1 Ceramidase Radical_SAM_C PF16199.5 CCH59288.1 - 1.8e-31 108.0 0.0 3.5e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CCH59288.1 - 2.1e-17 64.0 0.1 8.2e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CCH59288.1 - 8.7e-10 38.9 0.1 1.6e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCH59288.1 - 1.3e-06 28.4 0.1 3.4e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCH59288.1 - 0.013 15.9 0.1 0.025 15.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec16_C PF12931.7 CCH59289.1 - 2.1e-68 231.2 1.7 3.4e-68 230.5 1.7 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CCH59289.1 - 3.9e-09 37.1 0.2 4.9e-08 33.6 0.0 2.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region tRNA_int_end_N2 PF12928.7 CCH59290.1 - 6.6e-16 58.2 0.0 1.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 CCH59290.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain S4 PF01479.25 CCH59291.1 - 2.7e-12 46.2 0.2 2.7e-12 46.2 0.2 2.1 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CCH59291.1 - 0.00036 21.4 0.2 0.00063 20.6 0.2 1.7 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 CCH59292.1 - 5.8e-48 160.9 5.5 5.8e-48 160.9 5.5 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 CCH59292.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Mito_carr PF00153.27 CCH59293.1 - 1.7e-74 245.8 2.5 1.9e-27 95.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCH59293.1 - 0.039 13.1 0.0 4.6 6.3 0.0 3.1 3 0 0 3 3 3 0 Gammaproteobacterial serine protease GPI2 PF06432.11 CCH59294.1 - 3.5e-63 213.7 21.4 4.4e-63 213.4 21.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1741 PF08427.10 CCH59294.1 - 0.12 12.0 2.3 0.25 11.0 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) FA_desaturase PF00487.24 CCH59294.1 - 0.73 9.6 5.0 4.1 7.2 0.6 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF4131 PF13567.6 CCH59294.1 - 4.2 7.0 8.6 0.58 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) GCR1_C PF12550.8 CCH59295.1 - 2.6e-20 72.5 0.2 7.9e-20 71.0 0.2 1.9 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Med28 PF11594.8 CCH59295.1 - 0.006 16.7 0.5 0.006 16.7 0.5 2.9 2 1 0 2 2 2 1 Mediator complex subunit 28 TMEM52 PF14979.6 CCH59296.1 - 0.58 10.1 3.5 1.3 8.9 3.5 1.6 1 0 0 1 1 1 0 Transmembrane 52 Ribosomal_S30AE PF02482.19 CCH59296.1 - 5.9 7.7 11.1 1.3 9.9 0.9 2.6 3 0 0 3 3 3 0 Sigma 54 modulation protein / S30EA ribosomal protein AAA PF00004.29 CCH59297.1 - 7.3e-39 133.2 0.1 3.5e-38 131.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH59297.1 - 1.9e-08 34.0 0.0 5e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CCH59297.1 - 1.8e-06 28.0 1.8 0.0057 16.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCH59297.1 - 7.5e-05 22.5 0.0 0.00023 20.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 CCH59297.1 - 0.00022 21.2 0.0 0.0007 19.5 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CCH59297.1 - 0.00046 19.5 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CCH59297.1 - 0.0063 15.9 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CCH59297.1 - 0.02 15.2 0.0 0.02 15.2 0.0 3.6 2 2 1 3 3 2 0 AAA domain AAA_7 PF12775.7 CCH59297.1 - 0.027 14.0 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CCH59297.1 - 0.059 13.8 0.0 0.059 13.8 0.0 2.7 3 2 1 4 4 3 0 AAA ATPase domain AAA_33 PF13671.6 CCH59297.1 - 0.063 13.4 0.4 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCH59297.1 - 0.079 12.5 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCH59297.1 - 0.082 12.8 0.1 2.9 7.8 0.0 2.6 1 1 1 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 CCH59297.1 - 0.26 11.0 2.6 0.3 10.8 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein Glyco_transf_15 PF01793.16 CCH59298.1 - 8.8e-109 363.7 18.2 8.8e-109 363.7 18.2 1.7 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase DLP_helical PF18709.1 CCH59298.1 - 0.079 12.2 0.4 0.19 10.9 0.4 1.6 1 0 0 1 1 1 0 Dynamin-like helical domain tRNA_bind PF01588.20 CCH59299.1 - 3.2e-28 97.7 0.1 6.3e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain DUF3467 PF11950.8 CCH59299.1 - 0.042 14.0 0.7 0.18 12.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3467) Viral_protease PF08715.10 CCH59299.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Papain like viral protease NARP1 PF12569.8 CCH59299.1 - 0.54 9.1 9.0 0.8 8.5 9.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sugar_tr PF00083.24 CCH59300.1 - 6.3e-91 305.5 14.5 1.2e-90 304.6 14.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59300.1 - 2.1e-27 96.0 45.0 6.7e-25 87.8 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CCH59300.1 - 5.5e-08 32.5 8.0 5.5e-08 32.5 8.0 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 CCH59300.1 - 6.7e-06 24.8 3.3 6.7e-06 24.8 3.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1979 PF09322.10 CCH59300.1 - 0.013 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) DUF5510 PF17629.2 CCH59300.1 - 0.71 9.9 6.2 0.38 10.7 3.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5510) DUF1129 PF06570.11 CCH59300.1 - 0.71 9.3 5.0 2.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) Deltameth_res PF16020.5 CCH59300.1 - 3.8 7.4 4.8 2 8.4 0.6 2.9 2 1 0 2 2 2 0 Deltamethrin resistance Ribosomal_L27A PF00828.19 CCH59301.1 - 9e-22 78.1 0.0 1.3e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glycos_transf_4 PF00953.21 CCH59302.1 - 5.3e-31 107.8 12.2 5.3e-31 107.8 12.2 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF3413 PF11893.8 CCH59302.1 - 0.38 9.9 12.5 0.053 12.7 4.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) WD40 PF00400.32 CCH59303.1 - 1.7e-21 76.1 12.9 0.00038 21.2 0.3 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59303.1 - 4.4e-12 46.1 1.6 0.0049 17.1 0.0 4.4 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCH59303.1 - 2e-05 23.8 0.0 5.1 6.0 0.2 4.4 3 2 0 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein YmzC PF14157.6 CCH59303.1 - 0.047 13.8 0.0 47 4.2 0.0 3.7 4 0 0 4 4 4 0 YmzC-like protein Raptor_N PF14538.6 CCH59304.1 - 2.9e-66 221.9 0.2 5.5e-65 217.8 0.0 2.5 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CCH59304.1 - 7.7e-06 25.7 0.0 1.2 9.6 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat BBS2_Mid PF14783.6 CCH59304.1 - 9.2e-06 25.7 0.4 0.0046 17.0 0.1 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CCH59304.1 - 0.00023 21.9 8.9 13 6.8 0.0 6.5 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59304.1 - 0.00065 19.9 0.3 0.83 10.0 0.0 4.5 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 CCH59304.1 - 0.035 14.1 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCH59304.1 - 0.048 14.1 0.0 0.43 11.0 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats DnaJ_CXXCXGXG PF00684.19 CCH59305.1 - 4.4e-05 23.7 5.8 0.067 13.6 1.1 2.4 2 0 0 2 2 2 2 DnaJ central domain Apt1 PF10351.9 CCH59305.1 - 0.026 13.4 9.2 0.028 13.3 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PRIMA1 PF16101.5 CCH59305.1 - 0.053 13.6 2.9 0.11 12.5 2.9 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Macoilin PF09726.9 CCH59305.1 - 0.094 11.3 10.8 0.1 11.1 10.8 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CCH59305.1 - 1.6 7.4 6.0 1.9 7.1 6.0 1.1 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.10 CCH59305.1 - 3 7.5 24.4 6.1 6.5 24.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 KAR9 PF08580.10 CCH59305.1 - 9.1 4.7 21.8 11 4.4 21.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Got1 PF04178.12 CCH59306.1 - 3.1e-13 50.1 13.4 1.9e-12 47.6 13.1 1.9 1 1 1 2 2 2 2 Got1/Sft2-like family DUF308 PF03729.13 CCH59306.1 - 0.94 9.8 15.7 0.22 11.8 11.2 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) DUF373 PF04123.13 CCH59306.1 - 3.4 7.0 6.6 5.1 6.4 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) PTR2 PF00854.21 CCH59307.1 - 1.8e-99 333.3 15.7 7.1e-99 331.3 15.7 1.8 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 CCH59307.1 - 5e-07 29.0 29.2 5e-07 29.0 29.2 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Glyco_transf_15 PF01793.16 CCH59308.1 - 3.4e-112 374.9 9.2 3.4e-112 374.9 9.2 3.9 3 1 0 3 3 3 1 Glycolipid 2-alpha-mannosyltransferase Zn_clus PF00172.18 CCH59309.1 - 2.8e-06 27.3 11.0 4.6e-06 26.6 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Iron_permease PF04120.12 CCH59310.1 - 7.2e-29 100.2 17.3 3.4e-15 56.0 0.6 5.4 5 0 0 5 5 5 4 Low affinity iron permease DUF3589 PF12141.8 CCH59311.1 - 4.2e-84 282.9 12.1 3.8e-54 184.1 0.5 2.8 1 1 1 2 2 2 2 Beta-mannosyltransferases CPSF100_C PF13299.6 CCH59311.1 - 1.7 8.8 12.1 0.57 10.4 8.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3589 PF12141.8 CCH59312.1 - 4.5e-77 259.7 11.1 1.2e-47 162.7 0.3 2.7 2 1 1 3 3 3 2 Beta-mannosyltransferases Prefoldin_2 PF01920.20 CCH59312.1 - 0.76 9.8 3.7 1.9 8.5 3.7 1.6 1 0 0 1 1 1 0 Prefoldin subunit DUF3589 PF12141.8 CCH59313.1 - 2.5e-79 267.1 2.6 1.6e-54 185.3 0.0 2.3 1 1 0 2 2 2 2 Beta-mannosyltransferases Zn_clus PF00172.18 CCH59314.1 - 3.7e-07 30.1 13.1 6.6e-07 29.3 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 CCH59315.1 - 9.2e-165 548.9 35.3 1.1e-164 548.7 35.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59315.1 - 2.1e-30 105.8 22.9 2.1e-30 105.8 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CCH59315.1 - 0.00017 20.3 7.0 0.00017 20.3 7.0 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein ATP1G1_PLM_MAT8 PF02038.16 CCH59315.1 - 0.022 14.2 1.4 0.73 9.3 0.3 3.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1772 PF08592.11 CCH59315.1 - 2.7 8.3 11.1 1.7 8.9 4.8 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Transp_cyt_pur PF02133.15 CCH59316.1 - 2.3e-78 263.9 37.8 2.8e-78 263.7 37.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX7a PF02238.15 CCH59317.1 - 2.9e-23 82.0 0.1 3.3e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Hat1_N PF10394.9 CCH59318.1 - 9.3e-40 136.5 4.6 9.3e-40 136.5 4.6 2.0 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CCH59318.1 - 6.2e-05 23.2 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3127 PF11325.8 CCH59318.1 - 0.034 14.4 0.8 0.17 12.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3127) Acetyltransf_3 PF13302.7 CCH59318.1 - 0.11 13.2 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.16 CCH59319.1 - 1.3e-55 188.3 0.0 1.4e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Phage_Mu_Gam PF07352.12 CCH59319.1 - 0.025 14.5 3.5 0.063 13.2 0.2 2.5 2 1 1 3 3 3 0 Bacteriophage Mu Gam like protein KxDL PF10241.9 CCH59319.1 - 1.7 9.0 5.3 0.86 9.9 0.7 2.5 4 0 0 4 4 4 0 Uncharacterized conserved protein Fungal_TACC PF12709.7 CCH59320.1 - 0.041 14.3 3.1 7.6 7.1 0.1 2.8 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ThiF PF00899.21 CCH59320.1 - 0.056 12.8 0.1 0.95 8.8 0.0 2.8 3 0 0 3 3 3 0 ThiF family Pil1 PF13805.6 CCH59321.1 - 2.6e-117 391.0 0.2 4.3e-117 390.3 0.2 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 Nop10p PF04135.12 CCH59321.1 - 0.32 11.1 1.6 5.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Cwf_Cwc_15 PF04889.12 CCH59321.1 - 1 9.1 29.9 3.4 7.3 25.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 CCH59321.1 - 2 7.7 32.6 3.3 6.9 32.6 1.3 1 0 0 1 1 1 0 BUD22 PPR_2 PF13041.6 CCH59322.1 - 3.8e-14 52.6 1.7 1.4e-07 31.6 0.1 3.8 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.6 CCH59322.1 - 1.8e-11 43.9 5.0 9.4e-05 22.4 0.2 4.6 4 0 0 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 CCH59322.1 - 0.041 13.6 0.6 2.4 7.9 0.0 3.3 4 0 0 4 4 4 0 PPR repeat HDA2-3 PF11496.8 CCH59323.1 - 5.2e-83 278.6 0.8 5.2e-83 278.6 0.8 3.4 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Cep57_CLD PF14073.6 CCH59323.1 - 0.2 11.6 20.8 0.46 10.5 20.8 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 ThiF PF00899.21 CCH59324.1 - 2e-29 102.7 0.0 2.3e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCH59324.1 - 0.0084 16.2 0.1 0.023 14.8 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CCH59324.1 - 0.089 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1027 PF06265.11 CCH59324.1 - 0.11 12.5 1.0 4.8 7.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) Sec23_trunk PF04811.15 CCH59325.1 - 7.4e-72 241.8 0.0 1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CCH59325.1 - 5.2e-30 104.0 1.3 1.1e-29 103.0 1.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCH59325.1 - 9.7e-27 92.8 0.0 2.4e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCH59325.1 - 6.9e-13 48.4 9.8 1.3e-12 47.5 9.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCH59325.1 - 1.4e-12 47.4 0.0 3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CCH59325.1 - 0.00053 19.3 1.2 0.0012 18.2 1.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-MIZ PF02891.20 CCH59325.1 - 0.061 13.1 2.7 0.14 11.9 2.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PIG-U PF06728.13 CCH59326.1 - 8.4e-99 331.2 50.7 9.8e-99 331.0 50.7 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U MFA1_2 PF17317.2 CCH59327.1 - 3.2e-24 84.4 0.3 3.4e-24 84.3 0.3 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 LSM PF01423.22 CCH59328.1 - 1.1e-16 60.2 0.2 1.4e-16 59.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCH59328.1 - 0.048 13.8 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Glycos_transf_2 PF00535.26 CCH59329.1 - 1.8e-27 96.2 0.0 3.5e-27 95.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCH59329.1 - 3e-07 30.6 0.0 4.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CCH59329.1 - 0.037 13.5 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ATG13 PF10033.9 CCH59330.1 - 1.8e-61 207.9 2.8 4.1e-61 206.7 2.8 1.7 1 0 0 1 1 1 1 Autophagy-related protein 13 zf-C2H2 PF00096.26 CCH59331.1 - 1.3e-29 101.0 75.1 0.00013 22.2 2.8 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH59331.1 - 2.5e-23 80.7 72.0 5.8e-05 23.6 2.8 9.4 9 0 0 9 9 9 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH59331.1 - 4.9e-12 45.8 36.9 0.0089 16.3 1.8 8.5 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCH59331.1 - 7.9e-10 38.7 72.4 2.7e-05 24.4 2.6 9.9 11 0 0 11 11 11 6 Zinc-finger double domain zf-met PF12874.7 CCH59331.1 - 5.1e-08 33.0 40.8 0.052 14.0 1.5 8.8 9 1 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCH59331.1 - 0.00032 20.6 8.7 0.0046 16.9 0.9 6.8 8 0 0 8 8 8 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CCH59331.1 - 0.048 14.0 32.2 0.86 9.9 2.4 5.3 2 1 4 6 6 6 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 CCH59331.1 - 0.34 11.6 25.8 1 10.1 0.3 5.7 4 1 2 6 6 6 0 FOXP coiled-coil domain Retrotrans_gag PF03732.17 CCH59331.1 - 1.2 9.4 3.8 5.3 7.4 0.1 3.2 3 0 0 3 3 3 0 Retrotransposon gag protein zf-C2H2_2 PF12756.7 CCH59331.1 - 1.7 9.0 44.8 1.4 9.3 12.7 5.9 2 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 CCH59331.1 - 4.7 7.4 18.4 2.9 8.0 1.1 5.3 5 0 0 5 5 5 0 Zic proteins zinc finger domain RNA_pol_Rpb6 PF01192.22 CCH59332.1 - 1.9e-17 62.9 0.1 3e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_6 PF13405.6 CCH59333.1 - 1.9e-10 39.8 2.1 1.3e-06 27.9 0.2 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CCH59333.1 - 9.7e-10 38.8 0.6 1.6e-07 31.6 0.1 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CCH59333.1 - 1.9e-09 36.4 4.1 4.2e-05 22.8 0.3 4.3 4 1 1 5 5 5 3 EF hand EF-hand_5 PF13202.6 CCH59333.1 - 9.7e-08 31.2 1.4 9.8e-06 24.8 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CCH59333.1 - 0.00069 19.4 1.9 0.34 10.8 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair Dockerin_1 PF00404.18 CCH59333.1 - 0.022 15.0 0.5 0.22 11.7 0.3 2.1 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_14 PF17959.1 CCH59333.1 - 0.025 14.9 0.2 0.69 10.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain TPR_22 PF18833.1 CCH59334.1 - 6e-41 138.5 2.5 1.2e-40 137.5 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCH59334.1 - 2.7e-24 83.3 0.4 0.033 14.3 0.0 14.9 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH59334.1 - 2.4e-22 79.2 0.1 1e-06 29.1 0.0 8.7 8 1 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCH59334.1 - 2.3e-15 57.0 0.0 0.00018 22.1 0.0 8.3 7 2 2 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH59334.1 - 1.9e-14 53.1 0.0 18 6.5 0.0 11.1 8 2 4 12 12 12 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCH59334.1 - 2.3e-14 52.8 0.0 0.0033 17.1 0.0 8.9 7 1 1 8 8 8 2 TPR repeat TPR_1 PF00515.28 CCH59334.1 - 5.2e-14 51.4 8.6 0.041 13.7 0.0 11.4 13 1 0 13 13 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59334.1 - 1.1e-12 47.1 14.8 0.0024 18.0 0.0 11.2 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59334.1 - 1.9e-10 40.9 2.7 0.37 11.1 0.1 9.2 8 3 3 11 11 11 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCH59334.1 - 1.7e-09 37.4 3.0 1.2 9.7 0.0 9.2 10 0 0 10 10 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH59334.1 - 8.6e-09 35.5 3.2 0.011 16.0 0.0 7.0 7 1 1 8 8 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CCH59334.1 - 6.8e-08 32.7 0.1 58 4.6 0.0 9.1 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCH59334.1 - 0.00028 20.7 0.1 2 8.4 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCH59334.1 - 0.0006 19.9 0.0 1.9 8.7 0.0 5.7 6 1 1 7 7 6 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CCH59334.1 - 0.004 17.6 0.0 0.85 10.1 0.0 3.8 3 1 1 4 4 4 1 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 CCH59334.1 - 0.0075 15.9 0.0 0.2 11.3 0.0 3.3 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 CCH59334.1 - 0.01 15.2 0.0 0.46 9.8 0.0 2.9 2 0 0 2 2 2 0 MalT-like TPR region DUF4919 PF16266.5 CCH59334.1 - 0.027 14.4 3.3 1.7 8.6 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4919) PknG_TPR PF16918.5 CCH59334.1 - 0.03 13.1 0.0 2.1 7.0 0.0 3.1 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat RNA_pol_Rpc82 PF05645.13 CCH59335.1 - 9.2e-61 205.8 2.6 1.5e-60 205.1 2.6 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CCH59335.1 - 2.9e-20 72.1 5.9 1.9e-17 63.1 0.2 3.4 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CCH59335.1 - 2.1e-08 34.0 5.3 5.3e-07 29.5 0.1 3.6 4 0 0 4 4 4 1 TFIIE alpha subunit Penicillinase_R PF03965.16 CCH59335.1 - 0.0047 17.3 0.5 5.2 7.5 0.0 2.9 3 0 0 3 3 3 2 Penicillinase repressor Cwf_Cwc_15 PF04889.12 CCH59335.1 - 0.0094 15.7 3.2 0.018 14.8 3.2 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TSC22 PF01166.18 CCH59335.1 - 0.036 14.4 0.6 0.27 11.6 0.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Plasmid_parti PF01672.16 CCH59335.1 - 2.9 8.6 9.4 0.29 11.8 0.4 3.4 3 0 0 3 3 3 0 Putative plasmid partition protein Peptidase_M16 PF00675.20 CCH59336.1 - 8.6e-21 74.5 0.0 1.4e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCH59336.1 - 9.1e-06 25.8 0.3 4.5e-05 23.5 0.0 2.4 3 1 0 3 3 3 1 Peptidase M16 inactive domain Rhamnogal_lyase PF06045.11 CCH59336.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family Aa_trans PF01490.18 CCH59337.1 - 3.8e-30 104.9 38.9 4.9e-30 104.6 38.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 CCH59337.1 - 6 6.8 6.4 4.5 7.2 0.5 2.8 2 2 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus PLA2_B PF01735.18 CCH59338.1 - 4.1e-191 635.7 4.3 4.1e-191 635.7 4.3 1.7 2 0 0 2 2 2 1 Lysophospholipase catalytic domain IBR PF01485.21 CCH59338.1 - 0.0021 18.3 0.9 0.0045 17.2 0.9 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DEAD PF00270.29 CCH59339.1 - 1.2e-53 181.5 0.1 1.3e-52 178.1 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59339.1 - 2.2e-37 127.8 2.5 1.4e-31 109.1 0.1 3.5 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59339.1 - 7.8e-10 39.0 0.0 7.8e-10 39.0 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCH59339.1 - 1.8e-06 27.3 0.2 1.8e-06 27.3 0.2 2.7 3 0 0 3 3 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CCH59339.1 - 0.0045 17.3 0.0 0.29 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 CCH59339.1 - 0.0049 16.3 0.0 0.0049 16.3 0.0 3.5 2 2 0 2 2 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CCH59339.1 - 0.14 12.4 0.6 0.58 10.4 0.1 2.4 2 1 0 2 2 2 0 AAA domain SR-25 PF10500.9 CCH59339.1 - 0.26 10.8 22.0 0.7 9.5 22.0 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein UTP25 PF06862.12 CCH59339.1 - 0.54 9.0 18.3 0.016 14.0 1.3 3.7 3 1 1 4 4 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Zip PF02535.22 CCH59339.1 - 1.2 8.3 3.2 1.7 7.8 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AP3D1 PF06375.11 CCH59339.1 - 1.4 9.1 26.0 3.2 8.0 26.0 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 MAS20 PF02064.15 CCH59339.1 - 4.6 7.4 12.8 14 5.8 12.8 1.8 1 0 0 1 1 1 0 MAS20 protein import receptor NPR3 PF03666.13 CCH59339.1 - 5.2 5.7 12.6 8.2 5.1 12.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 CCH59339.1 - 7.9 5.7 11.0 12 5.0 11.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 NARP1 PF12569.8 CCH59339.1 - 8 5.2 22.2 16 4.3 22.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BSP_II PF05432.11 CCH59339.1 - 9.7 5.8 17.4 16 5.1 17.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) KxDL PF10241.9 CCH59340.1 - 5.3e-14 52.3 0.8 1.3e-13 51.0 0.8 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein SHOCT PF09851.9 CCH59340.1 - 0.074 12.8 1.8 0.52 10.1 0.1 2.9 3 0 0 3 3 3 0 Short C-terminal domain Adaptin_N PF01602.20 CCH59341.1 - 7.7e-87 292.0 34.4 1.2e-86 291.3 34.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCH59341.1 - 1.6e-12 47.8 1.9 1.6e-12 47.8 1.9 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Barstar PF01337.18 CCH59341.1 - 0.0031 17.5 0.0 0.0079 16.2 0.0 1.7 1 0 0 1 1 1 1 Barstar (barnase inhibitor) HEAT PF02985.22 CCH59341.1 - 0.016 15.4 0.2 55 4.4 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat DBD_HTH PF18430.1 CCH59341.1 - 0.03 14.1 0.2 0.11 12.3 0.2 2.0 1 0 0 1 1 1 0 Putative DNA-binding domain Vac14_Fab1_bd PF12755.7 CCH59341.1 - 0.11 13.1 3.0 1.5 9.5 0.3 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region GST_N_5 PF18485.1 CCH59341.1 - 0.15 12.4 0.1 0.48 10.8 0.1 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Med19 PF10278.9 CCH59341.1 - 3.4 7.6 33.5 80 3.1 31.0 3.1 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 NUFIP1 PF10453.9 CCH59342.1 - 6.9e-16 57.8 1.3 6.9e-16 57.8 1.3 3.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) AF-4 PF05110.13 CCH59342.1 - 2.3e-06 26.1 26.0 4.1e-06 25.2 26.0 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein MINDY_DUB PF04424.13 CCH59343.1 - 1.5e-28 99.2 0.0 3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase DUF1869 PF08956.10 CCH59343.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) RRM_1 PF00076.22 CCH59345.1 - 5e-09 35.8 0.1 1.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCH59345.1 - 0.0057 16.2 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.12 CCH59345.1 - 2.3 7.6 55.5 4.3e+02 0.1 55.5 2.2 1 1 0 1 1 1 0 SDA1 Pkinase PF00069.25 CCH59346.1 - 7.7e-25 87.7 0.1 1.4e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59346.1 - 6e-12 45.4 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MBOAT PF03062.19 CCH59347.1 - 3.2e-70 237.2 22.6 6.2e-70 236.3 22.6 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.17 CCH59348.1 - 1.4e-23 83.4 0.0 2.6e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.13 CCH59349.1 - 1.6e-21 76.4 10.1 1.6e-21 76.4 10.1 3.4 1 1 2 3 3 3 1 Mitotic checkpoint protein DUF1633 PF07794.11 CCH59349.1 - 0.064 11.4 4.9 0.14 10.4 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1633) YtxH PF12732.7 CCH59349.1 - 0.31 11.6 12.4 21 5.7 0.9 5.0 2 2 0 2 2 2 0 YtxH-like protein PKcGMP_CC PF16808.5 CCH59349.1 - 0.74 9.7 19.0 0.89 9.5 1.7 5.8 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SAP PF02037.27 CCH59349.1 - 4.3 7.2 6.7 0.3 10.9 0.2 2.6 3 0 0 3 3 3 0 SAP domain NAD_kinase PF01513.21 CCH59350.1 - 7.6e-54 182.9 0.0 9.9e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CCH59350.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MF_alpha_N PF05436.11 CCH59351.1 - 6e-30 103.0 0.1 8.4e-30 102.5 0.1 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.12 CCH59351.1 - 3.3e-21 74.6 42.0 0.00072 19.7 2.3 5.2 5 0 0 5 5 5 5 Yeast mating factor alpha hormone Apidaecin PF00807.17 CCH59351.1 - 1.3e-05 25.2 22.2 2.5 8.3 0.5 5.3 5 0 0 5 5 5 5 Apidaecin ParD_like PF11903.8 CCH59351.1 - 7.9e-05 22.7 2.1 63 3.8 0.0 5.2 5 0 0 5 5 5 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system DUF3225 PF11533.8 CCH59351.1 - 0.006 16.3 0.1 2.9 7.6 0.0 3.9 1 1 4 5 5 5 1 Protein of unknown function (DUF3225) TMEM132D_C PF15706.5 CCH59351.1 - 0.21 11.4 0.0 39 4.1 0.0 3.8 5 0 0 5 5 5 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term AMPK1_CBM PF16561.5 CCH59352.1 - 0.058 13.6 1.2 0.45 10.8 1.2 2.4 1 1 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase RRM_1 PF00076.22 CCH59353.1 - 6.4e-26 90.0 0.2 2.8e-07 30.2 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCH59353.1 - 3e-12 46.2 0.0 0.039 13.8 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_5 PF13893.6 CCH59353.1 - 3.5e-06 26.6 0.1 0.012 15.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCH59353.1 - 0.01 15.9 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif FtsH_ext PF06480.15 CCH59353.1 - 0.08 13.3 0.1 0.08 13.3 0.1 2.9 2 1 0 2 2 2 0 FtsH Extracellular Spc7 PF08317.11 CCH59355.1 - 1.9e-25 89.4 20.9 1.9e-25 89.4 20.9 2.6 2 1 0 2 2 2 1 Spc7 kinetochore protein Ribosomal_L36 PF00444.18 CCH59356.1 - 1.3e-19 70.1 9.8 1.9e-19 69.6 9.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Ntox33 PF15533.6 CCH59356.1 - 0.093 13.2 0.2 0.13 12.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial toxin 33 UCH_1 PF13423.6 CCH59357.1 - 3.2e-61 207.7 11.9 7.7e-61 206.4 11.9 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CCH59357.1 - 3e-16 60.4 0.0 5.9e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease ANAPC4_WD40 PF12894.7 CCH59357.1 - 0.027 14.8 0.0 0.89 9.9 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 CCH59358.1 - 1.9e-38 133.1 0.1 3.3e-38 132.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCH59358.1 - 2.9e-17 62.8 0.1 5.3e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Macoilin PF09726.9 CCH59358.1 - 2.1 6.8 19.1 2.7 6.4 19.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF5314 PF17241.2 CCH59359.1 - 6.2e-06 26.0 1.6 7.8e-06 25.7 1.2 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5314) DMAP1_like PF17024.5 CCH59359.1 - 0.017 15.2 0.5 0.04 14.0 0.5 1.6 1 0 0 1 1 1 0 Putative DMAP1-like Podoplanin PF05808.11 CCH59360.1 - 5.7 7.0 9.8 0.82 9.8 4.5 2.1 1 1 2 3 3 3 0 Podoplanin RNA_POL_M_15KD PF02150.16 CCH59361.1 - 1.8e-16 59.7 3.4 1.8e-16 59.7 3.4 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CCH59361.1 - 1.1e-14 54.0 14.0 2.2e-13 49.8 1.5 3.1 3 0 0 3 3 3 3 Transcription factor S-II (TFIIS) DZR PF12773.7 CCH59361.1 - 0.052 13.6 6.7 1.4 9.0 0.4 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-UBP PF02148.19 CCH59361.1 - 0.15 12.4 3.5 1.7 9.0 0.4 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_Tnp_IS1595 PF12760.7 CCH59361.1 - 0.26 11.3 10.0 1.8 8.6 2.1 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin PF00301.20 CCH59361.1 - 1.5 8.9 6.5 6 7.0 0.2 3.1 4 0 0 4 4 4 0 Rubredoxin Ribosomal_L12 PF00542.19 CCH59362.1 - 3.3e-22 78.6 6.9 3.3e-22 78.6 6.9 2.1 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CCH59362.1 - 5.9e-14 51.5 7.4 1.9e-13 49.9 4.1 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Pkinase PF00069.25 CCH59363.1 - 1.7e-23 83.3 0.0 4.8e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59363.1 - 3.1e-14 52.9 0.0 6.4e-14 51.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH59363.1 - 5.9e-09 35.2 0.0 5.9e-09 35.2 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase Macoilin PF09726.9 CCH59363.1 - 3.8 6.0 15.9 5.2 5.5 15.9 1.1 1 0 0 1 1 1 0 Macoilin family NUDIX PF00293.28 CCH59364.1 - 1.3e-12 47.9 0.0 2.4e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CCH59364.1 - 0.0015 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain GDPD PF03009.17 CCH59365.1 - 1.2e-22 80.9 0.1 4.8e-22 78.9 0.1 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SCA7 PF08313.12 CCH59366.1 - 8.8e-30 102.4 1.3 4.8e-29 100.1 1.3 2.4 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 CCH59366.1 - 2.1e-21 75.2 0.8 4.4e-21 74.2 0.8 1.6 1 0 0 1 1 1 1 Zinc finger domain Glycos_transf_1 PF00534.20 CCH59367.1 - 3.8e-37 127.5 0.1 6.1e-37 126.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCH59367.1 - 5.1e-15 55.9 0.0 7.6e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CCH59367.1 - 1.2e-09 38.7 0.0 7.2e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 CCH59367.1 - 1.1 9.2 3.9 16 5.4 0.0 3.1 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus Wyosine_form PF08608.12 CCH59368.1 - 4.4e-23 81.4 0.0 1.1e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CCH59368.1 - 2.5e-22 80.0 0.0 5.9e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CCH59368.1 - 1.2e-13 51.5 0.0 3.5e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 Flavodoxin BTRD1 PF17660.1 CCH59368.1 - 0.044 13.6 0.0 27 4.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial tandem repeat domain 1 RVT_2 PF07727.14 CCH59369.1 - 1e-31 110.5 2.2 1.1e-31 110.3 0.2 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CCH59369.1 - 2.4e-15 56.8 0.0 5.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 CCH59369.1 - 0.0087 15.6 0.0 0.043 13.3 0.0 2.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.6 CCH59369.1 - 0.11 12.3 0.1 0.59 10.0 0.1 2.3 1 0 0 1 1 1 0 GAG-pre-integrase domain Tubulin-binding PF00418.19 CCH59369.1 - 0.14 12.2 0.0 0.62 10.1 0.0 2.2 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat PAP2 PF01569.21 CCH59370.1 - 1.4e-19 70.2 3.8 2.9e-19 69.2 3.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CCH59370.1 - 0.096 12.4 1.5 0.19 11.4 1.5 1.6 1 0 0 1 1 1 0 PAP2 superfamily PAP2_C PF14360.6 CCH59370.1 - 0.15 12.6 2.5 0.46 11.0 2.5 1.8 1 0 0 1 1 1 0 PAP2 superfamily C-terminal PEX-2N PF09263.10 CCH59371.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal APS_kinase PF01583.20 CCH59372.1 - 1.3e-72 242.9 0.0 1.5e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCH59372.1 - 0.00011 22.4 0.0 0.0002 21.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH59372.1 - 0.00021 21.8 0.0 0.00036 21.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CCH59372.1 - 0.00029 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 CCH59372.1 - 0.00033 20.2 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CbiA PF01656.23 CCH59372.1 - 0.00046 20.2 0.0 0.00066 19.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.27 CCH59372.1 - 0.0013 19.2 0.0 0.0024 18.4 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.17 CCH59372.1 - 0.039 13.6 0.0 0.088 12.5 0.0 1.6 1 1 1 2 2 2 0 Thymidylate kinase SRP54 PF00448.22 CCH59372.1 - 0.061 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CCH59372.1 - 0.068 13.7 0.9 0.087 13.3 0.7 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCH59372.1 - 0.069 12.9 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CCH59372.1 - 0.092 13.1 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CCH59372.1 - 0.094 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CCH59372.1 - 0.19 11.0 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PAP2_3 PF14378.6 CCH59373.1 - 1.8e-21 76.7 5.9 1.8e-21 76.7 5.9 2.2 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CCH59373.1 - 2.7e-07 30.4 1.6 2.7e-07 30.4 1.6 2.4 2 1 0 2 2 2 1 PAP2 superfamily DUF1043 PF06295.12 CCH59374.1 - 0.0048 16.9 1.0 0.0054 16.7 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Use1 PF09753.9 CCH59374.1 - 0.013 15.2 0.3 0.014 15.2 0.3 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 CK2S PF15011.6 CCH59374.1 - 0.014 15.3 0.8 0.034 14.0 0.6 1.6 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF2451 PF10474.9 CCH59374.1 - 0.019 14.8 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Peptidase_C98 PF15499.6 CCH59374.1 - 0.07 12.6 0.1 0.079 12.4 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase SlyX PF04102.12 CCH59374.1 - 0.099 13.3 0.2 0.13 12.9 0.2 1.2 1 0 0 1 1 1 0 SlyX F-actin_cap_A PF01267.17 CCH59375.1 - 3.5e-77 259.4 1.3 4e-77 259.2 1.3 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit VHS PF00790.19 CCH59376.1 - 1e-30 106.5 1.8 3.3e-30 104.8 1.8 1.9 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CCH59376.1 - 9e-16 57.2 0.0 2.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCH59376.1 - 5.3e-15 54.8 0.0 1.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCH59376.1 - 1.1e-11 44.4 0.0 2.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CCH59376.1 - 0.0025 18.1 2.3 0.0025 18.1 2.3 4.2 3 2 1 4 4 4 1 GAT domain UIM PF02809.20 CCH59376.1 - 0.015 15.2 0.2 0.046 13.7 0.2 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif Hrs_helical PF12210.8 CCH59376.1 - 0.084 13.4 0.4 0.084 13.4 0.4 3.3 4 0 0 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate QIL1 PF15884.5 CCH59376.1 - 0.66 10.6 10.4 4.5 7.9 0.1 4.8 4 1 0 4 4 4 0 MICOS complex subunit MIC13, QIL1 TRAM_LAG1_CLN8 PF03798.16 CCH59377.1 - 9.3e-36 123.4 23.4 9.3e-36 123.4 23.4 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CCH59377.1 - 3.9e-19 68.1 1.7 9.5e-19 66.8 1.7 1.7 1 0 0 1 1 1 1 TRAM1-like protein Ribosomal_L10 PF00466.20 CCH59378.1 - 1.4e-17 63.7 0.0 2.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CCH59378.1 - 3.5e-17 62.1 0.0 5.4e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P CENP-C_C PF11699.8 CCH59379.1 - 1.1e-23 83.2 2.8 2.8e-23 81.9 2.8 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 CCH59379.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Mif2_N PF15624.6 CCH59379.1 - 0.0023 18.7 8.9 0.0023 18.7 8.9 4.0 2 2 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CRAL_TRIO PF00650.20 CCH59380.1 - 7.7e-37 126.5 0.1 1.4e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH59380.1 - 5.1e-09 36.2 1.3 1.2e-08 35.0 1.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCH59380.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GST_C_3 PF14497.6 CCH59380.1 - 0.02 15.1 0.0 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain vATP-synt_AC39 PF01992.16 CCH59380.1 - 0.09 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit DUF1769 PF08588.10 CCH59380.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) RasGAP PF00616.19 CCH59381.1 - 4.3e-37 127.9 9.5 2.1e-35 122.3 9.5 3.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CCH59381.1 - 0.23 11.8 2.4 0.27 11.6 0.1 2.4 2 0 0 2 2 2 0 C2 domain UPF1_Zn_bind PF09416.10 CCH59382.1 - 1.3e-64 216.7 5.8 1.3e-64 216.7 5.8 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CCH59382.1 - 6.4e-58 195.7 0.0 1.9e-57 194.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCH59382.1 - 1e-49 169.7 4.6 1.1e-26 94.2 0.7 2.5 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CCH59382.1 - 1.5e-27 95.6 0.0 3.3e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CCH59382.1 - 4.7e-16 59.1 0.0 3.2e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH59382.1 - 1.2e-13 51.7 0.1 2.3e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CCH59382.1 - 1.6e-06 28.2 0.0 4.7e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CCH59382.1 - 0.00025 20.4 0.6 0.003 16.8 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CCH59382.1 - 0.00041 20.2 0.0 0.49 10.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CCH59382.1 - 0.0022 17.9 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 CCH59382.1 - 0.0055 15.9 0.1 2.8 7.0 0.0 2.6 3 0 0 3 3 3 2 PIF1-like helicase PhoH PF02562.16 CCH59382.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DUF4088 PF13317.6 CCH59382.1 - 0.043 13.4 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) DEAD PF00270.29 CCH59382.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH59382.1 - 0.064 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCH59382.1 - 0.075 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.7 CCH59382.1 - 0.084 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.29 CCH59382.1 - 0.093 13.2 0.4 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 CCH59382.1 - 0.15 12.1 0.3 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain Transp_Tc5_C PF04236.15 CCH59382.1 - 5.6 7.4 7.3 0.47 10.8 1.6 2.2 2 0 0 2 2 1 0 Tc5 transposase C-terminal domain Hydrolase_4 PF12146.8 CCH59383.1 - 3.6e-49 167.2 0.0 4.2e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCH59383.1 - 4.8e-23 82.1 0.0 3.8e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCH59383.1 - 4.2e-09 37.3 0.0 5.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CCH59383.1 - 2.4e-06 27.2 0.0 0.0047 16.4 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 CCH59383.1 - 8.8e-05 21.5 0.0 0.00032 19.7 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme FSH1 PF03959.13 CCH59383.1 - 0.00051 19.8 0.1 0.072 12.7 0.0 2.4 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 CCH59383.1 - 0.016 14.7 0.1 1.7 8.1 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 CCH59383.1 - 0.022 13.8 0.1 0.77 8.7 0.0 2.4 2 1 0 2 2 2 0 Chlorophyllase LIDHydrolase PF10230.9 CCH59383.1 - 0.047 13.3 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 CCH59383.1 - 0.086 12.5 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DUF572 PF04502.13 CCH59384.1 - 1.5e-47 162.8 13.6 1.7e-47 162.6 13.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF3795 PF12675.7 CCH59384.1 - 0.32 11.4 0.1 0.32 11.4 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3795) AbrB-like PF14250.6 CCH59385.1 - 1.3 9.2 4.6 53 4.0 0.2 3.5 3 0 0 3 3 3 0 AbrB-like transcriptional regulator AAA_lid_2 PF17863.1 CCH59386.1 - 0.0067 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain Peptidase_A22B PF04258.13 CCH59387.1 - 9.2e-74 248.5 10.7 9.2e-74 248.5 10.7 1.6 2 0 0 2 2 2 1 Signal peptide peptidase Macro_2 PF14519.6 CCH59389.1 - 7.5e-69 232.2 0.0 8.7e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Ribophorin_II PF05817.14 CCH59390.1 - 3.4e-10 39.1 10.5 4.2e-10 38.8 10.4 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF2417 PF10329.9 CCH59390.1 - 1.3 8.4 4.8 0.3 10.5 1.8 1.5 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Peptidase_S24 PF00717.23 CCH59392.1 - 1.3e-07 31.4 0.1 2.8e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 CCH59392.1 - 0.051 13.4 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 adh_short PF00106.25 CCH59393.1 - 1.8e-10 40.6 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase ParG PF09274.10 CCH59393.1 - 0.019 15.1 0.4 0.045 13.9 0.4 1.8 1 1 0 1 1 1 0 ParG Epimerase PF01370.21 CCH59393.1 - 0.024 14.1 0.2 0.04 13.4 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-H3C2 PF16721.5 CCH59393.1 - 0.36 11.2 3.4 0.33 11.3 1.3 2.0 2 1 0 2 2 2 0 Zinc-finger like, probable DNA-binding AAA_14 PF13173.6 CCH59393.1 - 0.59 10.2 5.0 0.72 9.9 3.3 2.0 1 1 1 2 2 2 0 AAA domain LUC7 PF03194.15 CCH59394.1 - 3.6e-51 174.3 5.8 2.4e-49 168.3 2.5 2.0 1 1 1 2 2 2 2 LUC7 N_terminus DUF155 PF02582.14 CCH59394.1 - 0.0019 18.3 1.6 0.003 17.7 1.6 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2533 PF10752.9 CCH59394.1 - 0.065 13.7 3.7 0.3 11.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) IBD PF10416.9 CCH59394.1 - 0.98 9.4 8.1 0.18 11.8 1.9 2.6 2 1 1 3 3 3 0 Transcription-initiator DNA-binding domain IBD Nup35_RRM PF05172.13 CCH59395.1 - 5.2e-34 116.2 0.0 1.3e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CCH59395.1 - 0.02 14.9 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup54 PF13874.6 CCH59395.1 - 2.8 8.0 7.9 0.43 10.7 1.6 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 SRP14 PF02290.15 CCH59396.1 - 1e-23 83.5 0.5 1e-23 83.5 0.5 1.6 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Egg_lysin PF01303.17 CCH59396.1 - 0.016 15.5 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) Haem_bd PF14376.6 CCH59396.1 - 0.024 14.6 1.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Haem-binding domain Nodulin-like PF06813.13 CCH59397.1 - 1.4e-08 34.5 5.7 1.4e-08 34.5 5.7 2.7 2 1 0 2 2 2 2 Nodulin-like PMT PF02366.18 CCH59398.1 - 9.3e-77 257.9 23.4 9.3e-77 257.9 23.4 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCH59398.1 - 2.9e-60 203.3 20.2 2.9e-60 203.3 20.2 2.8 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCH59398.1 - 3.1e-47 160.8 1.4 5.1e-47 160.1 1.4 1.3 1 0 0 1 1 1 1 MIR domain DUP PF00674.18 CCH59400.1 - 3.1e-13 49.8 5.6 3.1e-13 49.8 5.6 1.9 1 1 1 2 2 2 1 DUP family TDA11 PF17084.5 CCH59401.1 - 8e-38 130.6 57.3 4.7e-27 95.0 25.6 4.2 1 1 3 4 4 4 4 Topoisomerase I damage affected protein 11 DUF4375 PF14300.6 CCH59402.1 - 0.24 11.7 5.1 0.1 12.9 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Colicin-DNase PF12639.7 CCH59402.1 - 4.8 8.1 13.8 3.2 8.6 6.7 3.0 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin PFK PF00365.20 CCH59403.1 - 1.1e-184 612.3 1.9 9.6e-105 350.0 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 CCH59403.1 - 4.8e-25 87.8 0.3 9.9e-25 86.8 0.3 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 CCH59403.1 - 0.12 12.0 0.2 0.55 9.9 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 CCH59403.1 - 0.17 11.7 0.4 0.39 10.5 0.4 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif ANTH PF07651.16 CCH59404.1 - 5.2e-61 206.1 1.6 5.2e-61 206.1 1.6 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CCH59404.1 - 1.8e-07 31.2 2.1 2e-07 31.1 0.0 2.2 3 0 0 3 3 3 1 ENTH domain MPC PF03650.13 CCH59405.1 - 3.5e-47 159.1 0.0 3.9e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Porin_3 PF01459.22 CCH59406.1 - 1.9e-64 217.7 8.6 2.2e-64 217.6 8.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin COX4 PF02936.14 CCH59407.1 - 7.9e-31 106.9 0.0 9.6e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 CCH59407.1 - 0.022 15.2 4.7 0.031 14.7 3.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) COG5 PF10392.9 CCH59408.1 - 2.6e-32 111.8 9.6 2.6e-32 111.8 9.6 3.1 2 1 0 2 2 2 1 Golgi transport complex subunit 5 SPARC_Ca_bdg PF10591.9 CCH59408.1 - 0.16 12.3 1.8 0.61 10.4 0.4 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2011 PF09428.10 CCH59409.1 - 2.6e-10 40.4 0.1 5.1e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Metallopep PF12044.8 CCH59410.1 - 1.8e-170 567.2 0.0 2.1e-170 567.0 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CCH59410.1 - 0.00015 21.7 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 CCH59410.1 - 0.0018 18.8 0.1 0.0039 17.7 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CCH59410.1 - 0.036 14.2 0.4 0.061 13.5 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CCH59410.1 - 0.11 11.4 1.6 0.16 10.9 0.2 1.9 2 0 0 2 2 2 0 Peptidase M66 Mob1_phocein PF03637.17 CCH59411.1 - 9.6e-67 224.2 0.4 1.3e-66 223.8 0.4 1.2 1 0 0 1 1 1 1 Mob1/phocein family AflR PF08493.10 CCH59411.1 - 4 6.8 8.8 5.4 6.4 8.8 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein ALG11_N PF15924.5 CCH59412.1 - 1.1e-78 264.1 0.9 2e-78 263.2 0.9 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CCH59412.1 - 2.6e-15 56.4 0.0 4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCH59412.1 - 0.00031 21.2 0.0 0.00069 20.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PH PF00169.29 CCH59413.1 - 3.6e-11 43.5 0.9 3.6e-11 43.5 0.9 2.2 2 0 0 2 2 2 1 PH domain DUF2722 PF10846.8 CCH59414.1 - 8.3e-23 81.1 16.8 1.1e-13 50.9 5.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2722) Pro_CA PF00484.19 CCH59415.1 - 1.2e-27 97.2 0.0 1.5e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase tRNA-synt_1d PF00750.19 CCH59415.1 - 0.048 12.6 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) CLTH PF10607.9 CCH59416.1 - 7.1e-24 84.4 7.8 7.1e-24 84.4 7.8 2.8 3 1 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain JUPITER PF17054.5 CCH59416.1 - 2.3 7.6 4.4 3.8 6.9 4.4 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Myb_DNA-bind_7 PF15963.5 CCH59417.1 - 1.2e-25 89.2 0.1 1.2e-25 89.2 0.1 3.7 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CCH59417.1 - 8e-09 35.6 0.0 2.1e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH59417.1 - 0.015 15.5 2.4 0.026 14.8 0.2 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF2948 PF11164.8 CCH59417.1 - 0.032 14.2 1.1 0.075 13.0 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) WD40 PF00400.32 CCH59418.1 - 1e-08 35.7 2.1 0.0071 17.2 0.3 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59418.1 - 5.9e-06 26.5 0.4 0.74 10.2 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CCH59418.1 - 0.029 13.4 0.5 2.7 6.9 0.2 2.7 1 1 1 2 2 2 0 Coatomer WD associated region RRP14 PF15459.6 CCH59418.1 - 0.13 12.9 7.6 0.29 11.8 7.6 1.6 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Peptidase_S49_N PF08496.10 CCH59418.1 - 5.4 7.1 6.9 5 7.2 5.4 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Pkinase PF00069.25 CCH59419.1 - 2.1e-36 125.7 0.0 4.9e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59419.1 - 1.2e-26 93.6 0.0 2.6e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Iso_dh PF00180.20 CCH59420.1 - 9.1e-107 357.2 0.0 1.1e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase R3H PF01424.22 CCH59421.1 - 3.5e-17 62.1 0.0 6.2e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CCH59421.1 - 2e-10 40.5 57.0 4.9e-07 29.7 16.1 11.4 11 0 0 11 11 11 4 NF-X1 type zinc finger MRP-S25 PF13741.6 CCH59422.1 - 1.3e-95 319.4 3.5 1.5e-95 319.2 3.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CCH59422.1 - 3.6e-08 33.7 1.8 1.2e-05 25.6 1.4 2.6 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 UTP25 PF06862.12 CCH59423.1 - 1.1e-199 664.1 16.8 1.1e-199 664.1 16.8 1.5 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CCH59423.1 - 3.1e-05 23.8 0.1 0.0011 18.7 0.1 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase POT1PC PF16686.5 CCH59423.1 - 0.00076 19.4 2.0 0.0018 18.2 0.8 2.3 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein ICE2 PF08426.10 CCH59424.1 - 1.3e-141 472.4 39.1 1.8e-141 471.9 39.1 1.2 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.23 CCH59425.1 - 4.3e-15 55.6 2.1 4.6e-14 52.2 0.2 2.6 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CCH59425.1 - 0.0038 17.6 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain Histone PF00125.24 CCH59426.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCH59426.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCH59426.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCH59426.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCH59426.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCH59426.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CCH59427.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCH59427.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CCH59427.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCH59427.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCH59427.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCH59427.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCH59427.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCH59427.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 CCH59428.1 - 5.1e-80 269.2 21.3 2.2e-51 175.0 11.1 2.2 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Tnp_P_element_C PF12596.8 CCH59428.1 - 0.094 13.3 1.2 0.22 12.1 1.2 1.6 1 0 0 1 1 1 0 87kDa Transposase Sds3 PF08598.11 CCH59429.1 - 1.2e-14 54.9 14.0 1.5e-14 54.5 14.0 1.2 1 0 0 1 1 1 1 Sds3-like DUF2018 PF09442.10 CCH59429.1 - 0.52 11.3 6.0 11 7.1 1.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) dbPDZ_assoc PF16610.5 CCH59429.1 - 5 7.4 9.2 16 5.8 1.8 2.3 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Met_10 PF02475.16 CCH59430.1 - 1.1e-09 38.4 0.0 2.3e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CCH59430.1 - 0.005 16.5 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 DUF3263 PF11662.8 CCH59430.1 - 0.067 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) MTS PF05175.14 CCH59430.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain zf-C2H2 PF00096.26 CCH59431.1 - 8.9e-13 47.9 12.3 1.5e-06 28.3 1.4 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH59431.1 - 2.7e-12 46.5 11.1 1.7e-06 28.1 0.4 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH59431.1 - 8.8e-09 35.5 10.4 0.0011 19.7 1.0 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 CCH59431.1 - 7.9e-08 32.4 4.6 6.5e-05 23.2 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCH59431.1 - 1.7e-07 31.4 7.2 0.0024 18.1 0.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCH59431.1 - 2e-05 24.5 7.2 0.073 13.1 0.3 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 CCH59431.1 - 0.0043 17.5 2.5 0.0043 17.5 2.5 2.0 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 CCH59431.1 - 0.05 13.2 3.5 0.25 11.0 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Endonuclease_7 PF02945.15 CCH59431.1 - 0.1 12.5 1.4 0.25 11.3 1.4 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII zf-BED PF02892.15 CCH59431.1 - 2.3 8.3 5.1 50 4.0 3.0 3.5 2 1 0 2 2 2 0 BED zinc finger Bac_surface_Ag PF01103.23 CCH59432.1 - 7.5e-45 153.8 14.2 1.5e-44 152.8 14.2 1.5 1 0 0 1 1 1 1 Surface antigen DFP PF04127.15 CCH59433.1 - 4e-14 52.9 0.0 1.1e-05 25.3 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein UCH PF00443.29 CCH59434.1 - 6.4e-42 143.8 15.3 1.5e-41 142.6 15.3 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH59434.1 - 0.0043 16.7 14.8 0.26 10.8 14.8 3.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase STN1_2 PF09170.10 CCH59434.1 - 0.0076 16.5 2.3 0.0076 16.5 2.3 2.0 2 0 0 2 2 2 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 ABC2_membrane_3 PF12698.7 CCH59435.1 - 0.035 13.2 0.2 0.043 12.9 0.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4834 PF16118.5 CCH59435.1 - 0.33 11.9 4.1 0.61 11.1 4.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ECSCR PF15820.5 CCH59435.1 - 8 6.4 7.7 2e+02 1.8 7.7 2.2 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Inhibitor_I9 PF05922.16 CCH59436.1 - 0.025 15.2 0.2 0.058 14.1 0.2 1.7 1 1 0 1 1 1 0 Peptidase inhibitor I9 Glyco_hydro_38N PF01074.22 CCH59437.1 - 1e-82 277.8 1.7 1.6e-82 277.1 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CCH59437.1 - 5.4e-51 173.7 1.1 5.4e-51 173.7 1.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CCH59437.1 - 8.3e-25 86.8 0.0 2.4e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CCH59437.1 - 5.2e-08 32.9 0.2 5.7e-07 29.5 0.1 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF4968 PF16338.5 CCH59437.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) Prenyltrans PF00432.21 CCH59438.1 - 4.7e-34 115.8 4.1 1.1e-07 31.4 0.0 6.8 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Polbeta PF18765.1 CCH59438.1 - 0.02 14.9 0.0 0.047 13.8 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase YajC PF02699.15 CCH59438.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit MDM31_MDM32 PF08118.11 CCH59439.1 - 1.2e-215 717.1 1.9 1.5e-215 716.9 1.9 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Glyco_hydro_47 PF01532.20 CCH59440.1 - 5.4e-139 464.0 3.0 6.4e-139 463.8 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Methyltransf_16 PF10294.9 CCH59441.1 - 1.5e-19 70.4 0.2 3.9e-19 69.1 0.1 1.7 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 CCH59441.1 - 0.0075 15.7 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CCH59441.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain zf-C2H2 PF00096.26 CCH59442.1 - 9.5e-08 32.1 13.1 0.00018 21.8 3.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH59442.1 - 4.2e-05 23.8 4.9 4.2e-05 23.8 4.9 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH59442.1 - 0.0068 17.1 15.8 0.09 13.7 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH59442.1 - 0.052 13.9 0.2 0.2 12.0 0.2 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Dus PF01207.17 CCH59443.1 - 1.2e-80 270.9 0.0 1.6e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF5617 PF18493.1 CCH59443.1 - 0.035 14.2 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5617) RICTOR_M PF14666.6 CCH59443.1 - 0.068 13.0 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Cupin_5 PF06172.11 CCH59444.1 - 7.2e-48 162.3 0.0 9e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) GW PF13457.6 CCH59444.1 - 0.079 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 GW (Gly-Tryp) dipeptide domain TFR_dimer PF04253.15 CCH59445.1 - 1.6e-11 44.4 0.0 6.3e-11 42.4 0.0 2.1 1 1 1 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.22 CCH59445.1 - 1.2e-07 31.6 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Pro_isomerase PF00160.21 CCH59446.1 - 3.6e-48 163.8 0.1 4.3e-48 163.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 CCH59447.1 - 4.8e-32 110.6 0.7 7.9e-32 109.9 0.7 1.4 1 0 0 1 1 1 1 ENTH domain Sybindin PF04099.12 CCH59448.1 - 5e-20 71.9 0.8 6.8e-20 71.5 0.8 1.1 1 0 0 1 1 1 1 Sybindin-like family RecG_wedge PF17191.4 CCH59448.1 - 0.037 13.6 0.1 0.048 13.3 0.1 1.2 1 0 0 1 1 1 0 RecG wedge domain Zn_clus PF00172.18 CCH59449.1 - 0.007 16.5 10.7 0.014 15.6 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FKBP_C PF00254.28 CCH59450.1 - 3.1e-28 97.9 0.1 1.1e-27 96.2 0.1 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CCH59450.1 - 8.2e-19 68.1 4.4 8.2e-19 68.1 4.4 2.9 2 1 0 2 2 2 1 Nucleoplasmin-like domain Na_trans_assoc PF06512.13 CCH59450.1 - 0.014 15.7 13.7 0.014 15.7 13.7 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated DDHD PF02862.17 CCH59450.1 - 0.33 11.1 9.2 2.7 8.1 0.5 2.2 2 0 0 2 2 2 0 DDHD domain GAGA_bind PF06217.12 CCH59450.1 - 1.3 9.2 23.8 1.2 9.4 2.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Mpp10 PF04006.12 CCH59450.1 - 1.7 7.0 53.3 1 7.7 18.0 2.0 2 0 0 2 2 2 0 Mpp10 protein Rtf2 PF04641.12 CCH59450.1 - 2.7 7.3 35.8 1 8.7 7.2 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF5308 PF17233.2 CCH59450.1 - 4.1 7.6 8.6 11 6.2 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Nop53 PF07767.11 CCH59450.1 - 6.3 6.1 51.7 2 7.7 14.6 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Neur_chan_memb PF02932.16 CCH59450.1 - 9.9 6.1 12.3 13 5.7 0.7 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Piwi PF02171.17 CCH59451.1 - 8.5e-68 228.8 0.7 1.8e-67 227.7 0.4 1.6 2 0 0 2 2 2 1 Piwi domain AGO_N PF18236.1 CCH59451.1 - 2.1e-47 160.3 1.3 2.1e-47 160.3 1.3 2.5 3 0 0 3 3 3 1 Argonaute N domain Ago_N_1 PF18351.1 CCH59451.1 - 3.9e-40 136.2 10.6 2.4e-39 133.7 1.2 3.9 4 0 0 4 4 4 2 Fungal Argonaute N-terminal domain PAZ PF02170.22 CCH59451.1 - 1e-05 25.3 0.1 2.9e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 CCH59451.1 - 0.0057 17.3 0.1 0.021 15.5 0.1 2.0 1 0 0 1 1 1 1 N-terminal domain of argonaute Velvet PF11754.8 CCH59451.1 - 0.059 13.3 13.0 0.048 13.6 10.2 2.1 2 0 0 2 2 2 0 Velvet factor Transformer PF06495.11 CCH59451.1 - 8.8 6.4 54.7 4.2 7.4 13.1 2.5 1 1 1 2 2 2 0 Fruit fly transformer protein Ribosomal_L6e PF01159.19 CCH59452.1 - 2.5e-38 131.0 2.9 3.8e-38 130.4 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DUF1007 PF06226.13 CCH59452.1 - 0.05 13.6 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) C2 PF00168.30 CCH59453.1 - 1.9e-58 195.1 0.2 1.8e-20 73.2 0.0 4.8 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 CCH59453.1 - 0.0041 16.6 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain vATP-synt_AC39 PF01992.16 CCH59454.1 - 3.9e-102 342.2 5.8 4.3e-102 342.1 5.8 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit DUF4806 PF16064.5 CCH59454.1 - 0.16 12.3 5.2 0.21 11.9 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) SF3A3 PF16837.5 CCH59454.1 - 0.93 10.0 4.2 24 5.5 0.1 3.2 2 1 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Cyt-b5 PF00173.28 CCH59455.1 - 9.9e-08 32.0 0.1 1.9e-07 31.1 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Hexokinase_2 PF03727.16 CCH59456.1 - 1.3e-19 70.6 0.0 2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCH59456.1 - 2.6e-13 50.3 0.3 4.2e-13 49.7 0.3 1.3 1 0 0 1 1 1 1 Hexokinase rpo132 PF12415.8 CCH59456.1 - 0.0072 15.6 1.5 6.5 6.1 0.1 3.6 3 0 0 3 3 3 2 Poxvirus DNA dependent RNA polymerase DUF1854 PF08909.11 CCH59456.1 - 0.083 12.7 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) Raptor_N PF14538.6 CCH59457.1 - 0.029 14.3 0.2 0.029 14.3 0.2 2.5 2 1 1 3 3 3 0 Raptor N-terminal CASPase like domain BAR PF03114.18 CCH59457.1 - 0.083 12.5 4.7 0.44 10.1 4.7 2.2 1 1 0 1 1 1 0 BAR domain CCD PF07860.11 CCH59457.1 - 0.16 12.0 0.8 0.44 10.6 0.8 1.7 1 0 0 1 1 1 0 WisP family C-Terminal Region Dak1 PF02733.17 CCH59458.1 - 3.5e-105 351.3 0.8 4.8e-105 350.9 0.8 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CCH59458.1 - 1.6e-46 158.4 0.4 3.7e-46 157.2 0.3 1.7 2 0 0 2 2 2 1 DAK2 domain HTH_7 PF02796.15 CCH59458.1 - 0.1 12.7 0.1 0.38 10.9 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase POB3_N PF17292.2 CCH59459.1 - 3.7e-30 104.2 0.2 1.6e-27 95.8 0.1 2.7 3 0 0 3 3 3 2 POB3-like N-terminal PH domain SSrecog PF03531.14 CCH59459.1 - 1.5e-29 101.7 1.5 7.3e-28 96.3 0.0 3.2 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 CCH59459.1 - 1.7e-28 98.9 0.0 4.4e-26 91.1 0.0 3.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF3127 PF11325.8 CCH59459.1 - 0.051 13.8 0.3 3.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) IBR PF01485.21 CCH59460.1 - 3e-10 40.2 46.6 3e-07 30.6 3.5 4.2 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CCH59460.1 - 0.0023 18.2 5.9 0.0023 18.2 5.9 4.4 3 2 2 5 5 5 1 Ring finger domain COPIIcoated_ERV PF07970.12 CCH59463.1 - 2.3e-28 99.6 0.0 3.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCH59463.1 - 6.5e-20 71.3 0.2 1.5e-19 70.1 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C2H2 PF00096.26 CCH59464.1 - 5.7e-07 29.6 12.7 0.0024 18.2 2.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH59464.1 - 9.2e-05 22.7 12.3 0.00016 22.0 0.7 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH59464.1 - 0.0015 19.2 15.7 0.078 13.9 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger MCM_OB PF17207.3 CCH59464.1 - 0.36 10.7 2.4 0.74 9.7 2.4 1.4 1 0 0 1 1 1 0 MCM OB domain zf-met PF12874.7 CCH59464.1 - 0.83 10.1 7.5 0.18 12.2 1.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Malic_M PF03949.15 CCH59465.1 - 1.2e-82 277.1 0.1 2e-82 276.4 0.1 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CCH59465.1 - 4e-63 212.5 0.2 3.7e-62 209.4 0.0 2.2 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Tugs PF17840.1 CCH59465.1 - 0.052 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain ThiF PF00899.21 CCH59466.1 - 2.8e-45 154.6 0.0 4.1e-45 154.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCH59466.1 - 0.00089 19.3 0.5 0.0028 17.7 0.5 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CCH59466.1 - 0.0014 18.9 1.0 0.011 15.9 1.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CCH59466.1 - 0.038 14.2 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CCH59466.1 - 0.065 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_14 PF13173.6 CCH59466.1 - 0.14 12.2 0.0 1.6 8.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain ApbA PF02558.16 CCH59466.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mito_carr PF00153.27 CCH59467.1 - 1.2e-58 195.0 1.2 2.2e-21 75.5 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2370 PF10176.9 CCH59468.1 - 9.4e-76 254.4 0.8 1.7e-75 253.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) QCR10 PF09796.9 CCH59469.1 - 1.7e-22 79.2 0.3 2.1e-22 78.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Oxysterol_BP PF01237.18 CCH59470.1 - 2.6e-85 286.5 2.6 8.2e-83 278.3 2.6 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Dynamin_M PF01031.20 CCH59471.1 - 2.7e-99 332.0 1.6 2.8e-99 331.9 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CCH59471.1 - 5.4e-56 189.3 0.4 2.3e-55 187.2 0.4 2.1 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CCH59471.1 - 3.7e-27 94.3 6.0 9.5e-27 93.0 6.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCH59471.1 - 0.00025 21.1 2.5 0.00092 19.3 2.5 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L1 PF00687.21 CCH59472.1 - 4.5e-35 121.3 7.9 5.5e-35 121.0 7.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MAAL_C PF07476.11 CCH59472.1 - 0.058 12.5 0.0 0.076 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus RNA_pol_Rpb4 PF03874.16 CCH59473.1 - 6.5e-35 120.1 7.9 1.1e-34 119.4 7.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 Telomere_res PF16684.5 CCH59473.1 - 0.019 14.5 0.4 0.026 14.0 0.4 1.1 1 0 0 1 1 1 0 Telomere resolvase Pkinase PF00069.25 CCH59474.1 - 3.8e-48 164.1 1.4 2.3e-47 161.6 1.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59474.1 - 7.1e-22 77.9 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CCH59474.1 - 0.0046 16.6 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CCH59474.1 - 0.0057 16.6 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCH59474.1 - 0.11 12.0 2.3 0.089 12.4 0.4 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase CRAL_TRIO PF00650.20 CCH59476.1 - 4.8e-23 81.6 0.2 9.5e-23 80.7 0.1 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH59476.1 - 5.4e-05 23.3 1.0 0.00011 22.3 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain RNA_polI_A34 PF08208.11 CCH59477.1 - 1.8e-28 100.1 20.3 1.8e-28 100.1 20.3 1.6 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.6 CCH59477.1 - 0.0035 17.8 18.7 0.0035 17.8 18.7 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4604) Clathrin_lg_ch PF01086.17 CCH59480.1 - 1.3e-29 103.9 5.1 1.4e-29 103.8 5.1 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4521 PF15021.6 CCH59480.1 - 0.019 14.9 0.3 0.02 14.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) MAP7 PF05672.11 CCH59480.1 - 0.1 12.3 5.8 0.12 12.0 5.8 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF883 PF05957.13 CCH59480.1 - 0.11 13.1 1.1 0.14 12.8 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RBB1NT PF08169.11 CCH59480.1 - 0.17 12.1 1.7 0.28 11.3 1.7 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain DUF4337 PF14235.6 CCH59480.1 - 1.7 8.7 5.0 2 8.5 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Trs65 PF12735.7 CCH59481.1 - 4.6e-45 154.4 9.2 6.7e-45 153.9 9.2 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 RXT2_N PF08595.11 CCH59481.1 - 0.0072 16.4 6.6 0.02 14.9 6.6 1.8 1 0 0 1 1 1 1 RXT2-like, N-terminal Nop14 PF04147.12 CCH59481.1 - 0.0081 14.4 6.4 0.012 13.9 6.4 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 CCH59481.1 - 0.023 13.0 3.3 0.031 12.6 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CCH59481.1 - 0.044 13.4 5.7 0.081 12.6 5.7 1.3 1 0 0 1 1 1 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 CCH59481.1 - 0.052 13.8 15.9 0.1 12.8 15.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 CCH59481.1 - 0.2 10.8 7.0 0.36 10.0 7.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FYDLN_acid PF09538.10 CCH59481.1 - 0.3 11.8 10.3 0.53 11.0 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 CCH59481.1 - 0.6 10.5 18.5 1.2 9.6 18.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CCH59481.1 - 0.95 8.7 16.9 1.5 8.1 16.9 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 CCH59481.1 - 1.6 8.5 11.1 2.8 7.7 11.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 CCH59481.1 - 6.4 4.7 17.4 10 4.1 17.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Bot1p PF12298.8 CCH59482.1 - 2.2e-47 161.5 0.1 3.5e-47 160.8 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Sad1_UNC PF07738.13 CCH59483.1 - 7.6e-09 35.7 0.4 1.8e-07 31.2 0.0 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal SF-assemblin PF06705.11 CCH59483.1 - 0.027 13.8 3.6 0.069 12.5 3.6 1.6 1 0 0 1 1 1 0 SF-assemblin/beta giardin YabA PF06156.13 CCH59483.1 - 0.37 11.5 2.3 1.3 9.7 2.3 2.0 1 0 0 1 1 1 0 Initiation control protein YabA SPATA1_C PF15743.5 CCH59483.1 - 0.39 10.8 2.9 1.1 9.3 2.9 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus NPV_P10 PF05531.12 CCH59483.1 - 1 9.9 7.5 11 6.6 0.8 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ING PF12998.7 CCH59483.1 - 3.1 8.4 10.9 0.25 12.0 3.9 2.8 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Vma12 PF11712.8 CCH59483.1 - 9.9 6.2 6.6 2.9e+02 1.5 6.6 2.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mad3_BUB1_I PF08311.12 CCH59485.1 - 2.4e-36 124.4 2.7 5.3e-36 123.3 2.7 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CCH59485.1 - 1.1e-27 95.9 0.0 8.1e-26 90.0 0.1 3.6 3 1 1 4 4 4 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 CCH59485.1 - 5.4e-17 62.0 0.2 1.8e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59485.1 - 4.8e-06 26.0 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 CCH59485.1 - 0.0021 18.2 4.1 0.0031 17.6 2.6 2.1 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 CCH59485.1 - 0.017 14.4 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like WSN PF02206.18 CCH59485.1 - 0.11 12.5 1.1 1.2 9.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function VTC PF09359.10 CCH59486.1 - 2.1e-100 335.7 0.2 2.1e-100 335.7 0.2 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CCH59486.1 - 3.1e-11 43.8 12.1 2.1e-05 24.6 2.2 3.3 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 CCH59486.1 - 3.5e-10 40.2 4.0 7.3e-10 39.2 4.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Phage_hub_GP28 PF11110.8 CCH59486.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Baseplate hub distal subunit ASF1_hist_chap PF04729.13 CCH59487.1 - 7.4e-71 237.1 0.1 1.3e-70 236.3 0.1 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.10 CCH59487.1 - 0.011 15.1 48.9 0.016 14.6 48.9 1.1 1 0 0 1 1 1 0 BUD22 SUN PF03856.13 CCH59488.1 - 8.9e-97 323.4 18.9 1.5e-96 322.6 18.9 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) AMP_N PF05195.16 CCH59488.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain His_Phos_1 PF00300.22 CCH59489.1 - 4.8e-35 121.0 0.0 6e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CCH59489.1 - 0.0033 16.8 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YqbF PF14553.6 CCH59489.1 - 0.1 12.5 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 YqbF, hypothetical protein domain F-actin_cap_A PF01267.17 CCH59490.1 - 0.0037 16.7 0.2 0.0071 15.8 0.2 1.4 1 0 0 1 1 1 1 F-actin capping protein alpha subunit DUF4903 PF16246.5 CCH59490.1 - 0.017 14.7 1.8 0.033 13.8 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) MFS_Mycoplasma PF07672.13 CCH59490.1 - 0.022 14.1 0.3 3.3 6.9 0.0 2.3 2 0 0 2 2 2 0 Mycoplasma MFS transporter CTP-dep_RFKase PF01982.16 CCH59490.1 - 0.093 12.8 0.3 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF120 Pho86 PF11124.8 CCH59491.1 - 7e-103 344.1 5.1 7.8e-103 343.9 5.1 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 ThrE PF06738.12 CCH59491.1 - 0.11 11.9 3.3 0.16 11.3 3.3 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter PET10 PF17316.2 CCH59492.1 - 1.2e-69 234.6 6.5 2.1e-67 227.3 6.5 2.6 1 1 0 1 1 1 1 Petite colonies protein 10 Mod_r PF07200.13 CCH59492.1 - 0.44 10.6 4.6 0.092 12.8 0.6 1.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein SNAPc19 PF15497.6 CCH59492.1 - 6 7.4 11.2 1 9.8 0.2 3.3 1 1 1 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Glyco_hydro_16 PF00722.21 CCH59493.1 - 1.1e-44 152.0 0.3 1.1e-44 152.0 0.3 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Utp14 PF04615.13 CCH59493.1 - 3.3 6.2 28.7 4.2 5.8 28.7 1.0 1 0 0 1 1 1 0 Utp14 protein DUF966 PF06136.13 CCH59493.1 - 5.3 6.7 35.4 7.5 6.2 35.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SOBP PF15279.6 CCH59493.1 - 8.6 6.9 26.6 17 5.9 26.6 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein adh_short PF00106.25 CCH59494.1 - 1.7e-12 47.2 0.0 1.2e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH59494.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH59494.1 - 0.052 13.4 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Ribosomal_S10 PF00338.22 CCH59495.1 - 7.1e-25 87.1 0.6 8.7e-25 86.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Sipho_Gp157 PF05565.11 CCH59495.1 - 0.031 14.3 0.6 0.039 14.0 0.6 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Lung_7-TM_R PF06814.13 CCH59496.1 - 3.5e-82 276.0 25.8 4.7e-82 275.6 25.8 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor NifU PF01106.17 CCH59497.1 - 6.1e-26 90.4 0.0 1.2e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CCH59497.1 - 3.1e-22 78.4 0.0 6.9e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.9 CCH59497.1 - 0.0013 18.8 0.4 0.0035 17.4 0.4 1.7 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus BA14K PF07886.11 CCH59497.1 - 0.13 12.1 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 BA14K-like protein Adap_comp_sub PF00928.21 CCH59498.1 - 1.1e-64 218.4 10.9 1.5e-52 178.6 1.6 2.8 3 0 0 3 3 3 2 Adaptor complexes medium subunit family Chitin_synth_2 PF03142.15 CCH59499.1 - 9.7e-282 935.2 0.0 1.4e-281 934.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CCH59499.1 - 1.8e-12 47.7 0.0 1.1e-09 38.6 0.0 2.3 1 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CCH59499.1 - 4.2e-11 43.1 2.5 2.1e-10 40.9 2.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CCH59499.1 - 0.0061 16.4 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CCH59499.1 - 0.027 14.0 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Nucleoporin2 PF04096.14 CCH59501.1 - 3.3e-32 111.7 0.8 1.6e-31 109.4 0.0 2.4 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 CCH59501.1 - 5.1e-31 107.4 316.4 5.3e-09 36.8 39.1 10.5 2 1 9 11 11 11 9 Nucleoporin FG repeat region BSMAP PF12280.8 CCH59501.1 - 7 6.8 11.0 0.51 10.5 5.0 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein Bac_rhodopsin PF01036.18 CCH59502.1 - 3.8e-55 186.9 17.1 4.4e-55 186.7 17.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Retrotrans_gag PF03732.17 CCH59503.1 - 1.8e-10 40.9 0.0 8.4e-10 38.8 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CCH59503.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) zf-CCHC PF00098.23 CCH59503.1 - 0.019 15.0 0.6 0.019 15.0 0.6 1.8 2 0 0 2 2 2 0 Zinc knuckle DUF3007 PF11460.8 CCH59503.1 - 0.067 13.4 0.1 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) DUF2591 PF10765.9 CCH59503.1 - 0.14 12.4 0.0 4.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2591) Peptidase_A2B PF12384.8 CCH59504.1 - 1e-11 44.7 0.0 1.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.6 CCH59504.1 - 0.00016 22.2 0.0 0.00027 21.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCH59504.1 - 0.00036 21.0 0.0 0.00054 20.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CCH59504.1 - 0.0069 16.2 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease PDZ_assoc PF10600.9 CCH59504.1 - 2.1 9.3 5.2 1.7 9.5 0.2 2.7 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors RVT_1 PF00078.27 CCH59505.1 - 9.9e-29 100.4 0.1 1.9e-27 96.2 0.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCH59505.1 - 1e-26 92.9 0.0 2.2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH59505.1 - 3.1e-24 85.3 0.0 8.1e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 CCH59506.1 - 5.9e-05 23.2 0.0 9.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CCH59506.1 - 0.0013 18.8 1.4 0.0023 18.0 0.7 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain SRF-TF PF00319.18 CCH59507.1 - 4.8e-21 74.0 0.2 7.1e-21 73.4 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TraG_N PF07916.11 CCH59507.1 - 2.8 6.7 14.3 3.9 6.2 14.3 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SID-1_RNA_chan PF13965.6 CCH59507.1 - 3.8 5.8 5.1 4.9 5.4 5.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PWWP PF00855.17 CCH59508.1 - 1.7e-19 70.0 0.1 1.7e-19 70.0 0.1 2.5 2 0 0 2 2 2 1 PWWP domain Bac_rhodopsin PF01036.18 CCH59509.1 - 3.5e-49 167.4 20.2 4.1e-49 167.2 20.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Bac_rhodopsin PF01036.18 CCH59510.1 - 2.8e-49 167.7 17.4 3.2e-49 167.5 17.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCH59510.1 - 0.075 12.7 4.7 5 6.7 1.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_15 PF00723.21 CCH59511.1 - 1.1e-56 192.5 0.0 1.5e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Iso_dh PF00180.20 CCH59512.1 - 3.7e-77 259.8 0.1 4.2e-77 259.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2431 PF10354.9 CCH59513.1 - 8.5e-51 172.5 1.0 8.5e-51 172.5 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Band_3_cyto PF07565.13 CCH59513.1 - 1.3 8.8 5.5 0.18 11.6 1.0 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pre-PUA PF17832.1 CCH59513.1 - 6.5 7.5 8.8 9.7 7.0 6.8 2.3 1 1 1 2 2 2 0 Pre-PUA-like domain PIG-H PF10181.9 CCH59514.1 - 5.3e-22 77.5 0.3 9.4e-22 76.7 0.3 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component DUF2721 PF11026.8 CCH59514.1 - 0.059 13.3 2.8 0.098 12.5 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) YukC PF10140.9 CCH59514.1 - 0.095 11.5 1.4 0.12 11.2 1.4 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pkinase PF00069.25 CCH59515.1 - 1.5e-39 136.0 0.0 3.3e-39 134.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59515.1 - 1e-25 90.5 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59515.1 - 0.0088 15.4 0.0 0.024 13.9 0.0 1.8 1 0 0 1 1 1 1 Kinase-like GP40 PF11025.8 CCH59515.1 - 7.3 6.3 12.8 1.2 8.9 6.8 2.9 2 1 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Hist_deacetyl PF00850.19 CCH59516.1 - 1.5e-86 290.7 0.0 2.1e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 CCH59516.1 - 3.8e-86 288.4 0.6 5.4e-82 274.8 0.1 2.3 2 0 0 2 2 2 2 Arb2 domain NTNH_C PF08470.10 CCH59516.1 - 0.013 15.4 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal Methyltr_RsmB-F PF01189.17 CCH59517.1 - 6.3e-18 65.1 0.0 1.2e-10 41.4 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1242 PF06842.12 CCH59518.1 - 3e-14 52.5 0.4 3.9e-14 52.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) ICE2 PF08426.10 CCH59519.1 - 5.5e-143 476.9 34.3 9e-143 476.2 34.3 1.3 1 1 0 1 1 1 1 ICE2 Cullin PF00888.22 CCH59519.1 - 0.0029 16.3 0.1 0.0045 15.7 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cep3 PF16846.5 CCH59520.1 - 7.2e-18 64.3 18.7 1.6e-17 63.2 18.7 1.5 1 1 1 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 CCH59520.1 - 5.4e-05 23.2 9.3 5.4e-05 23.2 9.3 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4041 PF13250.6 CCH59520.1 - 0.069 13.0 0.4 0.23 11.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) RINT1_TIP1 PF04437.13 CCH59521.1 - 1.6e-46 159.2 40.4 1.6e-46 159.2 40.4 2.3 2 1 0 2 2 2 1 RINT-1 / TIP-1 family HECT PF00632.25 CCH59522.1 - 7.4e-79 265.4 1.0 7.4e-79 265.4 1.0 2.5 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CCH59523.1 - 3.3e-12 46.6 0.0 9e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 SPRY domain YL1 PF05764.13 CCH59523.1 - 0.002 18.3 16.5 0.002 18.3 16.5 2.6 3 0 0 3 3 3 1 YL1 nuclear protein Transformer PF06495.11 CCH59523.1 - 0.41 10.7 21.3 0.061 13.4 10.7 2.4 2 0 0 2 2 2 0 Fruit fly transformer protein Zn_clus PF00172.18 CCH59524.1 - 3.9e-08 33.3 7.3 7.9e-08 32.3 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeodomain PF00046.29 CCH59526.1 - 1e-17 63.7 3.0 1e-17 63.7 3.0 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CCH59526.1 - 0.0056 16.6 0.3 0.021 14.7 0.3 2.0 1 0 0 1 1 1 1 Homeobox KN domain DUF5473 PF17567.2 CCH59526.1 - 0.56 10.5 4.9 1.4 9.2 1.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5473) PX PF00787.24 CCH59527.1 - 9.5e-19 67.5 3.2 2e-18 66.4 0.1 3.0 3 1 0 3 3 3 1 PX domain Chorismate_synt PF01264.21 CCH59528.1 - 1.1e-139 464.7 0.0 1.3e-139 464.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SNF2_N PF00176.23 CCH59529.1 - 1.9e-66 224.2 2.8 1.9e-66 224.2 2.8 2.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 CCH59529.1 - 1.4e-46 158.2 22.2 1.4e-46 158.2 22.2 3.7 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 CCH59529.1 - 2.4e-17 63.3 0.0 1.8e-16 60.5 0.0 2.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ACPS PF01648.20 CCH59530.1 - 8.3e-13 48.5 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Mito_carr PF00153.27 CCH59531.1 - 2.8e-48 161.8 3.7 1.3e-18 66.7 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.16 CCH59532.1 - 2.5e-37 127.3 0.0 4.7e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Frataxin-like domain BESS PF02944.20 CCH59532.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 BESS motif UCH PF00443.29 CCH59533.1 - 2.7e-09 36.9 16.1 1.5e-08 34.5 16.1 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.22 CCH59534.1 - 6.8e-54 179.6 0.3 1e-17 63.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCH59534.1 - 4.3e-06 26.3 0.9 0.0036 16.9 0.1 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCH59534.1 - 7.5e-06 25.7 0.0 0.054 13.4 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CCH59534.1 - 0.00088 19.4 0.1 0.22 11.7 0.0 3.6 4 0 0 4 4 4 1 RNA recognition motif DbpA PF03880.15 CCH59534.1 - 0.14 12.2 0.1 14 5.7 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain DUF3421 PF11901.8 CCH59534.1 - 0.15 12.1 0.1 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) PHM7_cyt PF14703.6 CCH59534.1 - 1.3 9.3 4.6 8.4 6.6 0.0 3.4 3 2 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Sds3 PF08598.11 CCH59535.1 - 1.1e-70 238.0 20.0 1.8e-70 237.4 20.0 1.3 1 0 0 1 1 1 1 Sds3-like DUF484 PF04340.12 CCH59535.1 - 0.0029 17.3 0.8 0.0049 16.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF484 Aim19 PF10315.9 CCH59536.1 - 2.5e-30 105.1 3.6 6.6e-30 103.8 1.6 1.9 1 1 1 2 2 2 2 Altered inheritance of mitochondria protein 19 Y_phosphatase2 PF03162.13 CCH59537.1 - 1.7e-57 193.6 0.0 3.6e-57 192.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCH59537.1 - 6.5e-06 26.3 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CCH59537.1 - 0.0096 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCH59537.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Aa_trans PF01490.18 CCH59538.1 - 1.5e-97 326.9 34.7 1.8e-97 326.6 34.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_phi PF04931.13 CCH59539.1 - 0.00062 18.0 8.9 0.00062 18.0 8.9 2.1 3 0 0 3 3 3 1 DNA polymerase phi DUF2052 PF09747.9 CCH59539.1 - 0.0062 16.7 11.4 0.012 15.7 11.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 CCH59539.1 - 0.024 12.9 14.5 0.051 11.8 14.5 1.5 1 0 0 1 1 1 0 Nop14-like family Dimer_Tnp_hAT PF05699.14 CCH59539.1 - 0.032 14.0 0.3 0.032 14.0 0.3 2.2 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region MYCBPAP PF14646.6 CCH59539.1 - 0.72 8.7 9.2 0.11 11.4 4.0 2.1 2 0 0 2 2 2 0 MYCBP-associated protein family CDC45 PF02724.14 CCH59539.1 - 1.4 7.2 10.1 2.5 6.3 10.1 1.3 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CCH59539.1 - 1.7 8.3 8.5 4.1 7.1 8.5 1.6 1 0 0 1 1 1 0 FAM176 family E7 PF00527.18 CCH59539.1 - 3.2 8.0 8.0 39 4.5 5.6 2.8 2 0 0 2 2 2 0 E7 protein, Early protein RNA_pol_3_Rpc31 PF11705.8 CCH59539.1 - 5.1 7.3 22.7 14 5.9 22.7 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 CCH59539.1 - 5.9 7.3 19.1 6.4 7.2 16.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FYDLN_acid PF09538.10 CCH59539.1 - 6.7 7.4 13.2 18 6.0 13.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nse4_C PF08743.10 CCH59541.1 - 1.2e-29 102.4 1.2 1.2e-29 102.4 1.2 2.4 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CCH59541.1 - 1.7e-16 60.1 0.4 3.9e-16 58.9 0.4 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Peptidase_M22 PF00814.25 CCH59542.1 - 2.1e-67 227.7 0.0 2.6e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Mito_carr PF00153.27 CCH59543.1 - 1.1e-57 192.0 2.5 4.3e-19 68.2 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.13 CCH59544.1 - 1.3e-92 309.4 0.1 2e-70 236.8 0.0 2.5 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CCH59544.1 - 1.4e-41 140.6 0.0 3.5e-41 139.3 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region LisH PF08513.11 CCH59545.1 - 4.6e-05 23.2 1.7 0.0001 22.1 1.7 1.7 1 0 0 1 1 1 1 LisH PIR PF00399.19 CCH59546.1 - 7.3e-40 133.7 81.4 5.9e-08 32.1 2.5 8.6 8 0 0 8 8 8 8 Yeast PIR protein repeat DUF1043 PF06295.12 CCH59547.1 - 0.046 13.7 2.1 0.19 11.7 2.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Vac_Fusion PF02346.16 CCH59547.1 - 0.76 9.4 6.1 4.8 6.9 0.3 4.3 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 UDPGP PF01704.18 CCH59548.1 - 2.9e-49 167.8 0.0 5.3e-49 167.0 0.0 1.3 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase E1-E2_ATPase PF00122.20 CCH59549.1 - 0.0047 16.5 0.3 0.022 14.3 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase COX7C PF02935.16 CCH59549.1 - 2.9 8.2 5.6 0.9 9.8 0.8 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DNA_pol_B PF00136.21 CCH59550.1 - 1.1e-144 482.6 0.2 1.8e-144 481.9 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCH59550.1 - 2.5e-85 286.6 2.9 5.9e-85 285.4 2.9 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCH59550.1 - 2.5e-16 59.9 8.2 5.5e-16 58.8 8.2 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CCH59550.1 - 0.00025 20.1 3.8 0.0026 16.7 0.3 2.8 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CCH59550.1 - 0.027 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB FAM91_N PF14647.6 CCH59550.1 - 0.073 12.3 0.1 0.24 10.7 0.1 1.8 1 0 0 1 1 1 0 FAM91 N-terminus Pkinase PF00069.25 CCH59551.1 - 1.1e-69 234.7 0.0 1.7e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59551.1 - 3.6e-36 124.8 0.0 6.2e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCH59551.1 - 1.8e-15 57.0 0.6 4.9e-15 55.6 0.6 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCH59551.1 - 2.7e-05 24.4 0.7 6.5e-05 23.2 0.1 2.0 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 CCH59551.1 - 0.00066 18.6 0.0 0.0009 18.1 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCH59551.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATG16 PF08614.11 CCH59553.1 - 1.8e-12 48.0 10.8 1.8e-12 48.0 10.8 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 CCH59553.1 - 0.00095 19.4 4.9 0.0014 18.8 4.9 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding MPS2 PF17060.5 CCH59553.1 - 0.0031 16.8 6.4 0.0035 16.7 6.4 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 Fez1 PF06818.15 CCH59553.1 - 0.0038 17.7 2.9 0.0048 17.4 2.9 1.2 1 0 0 1 1 1 1 Fez1 DUF641 PF04859.12 CCH59553.1 - 0.021 15.1 3.1 0.021 15.1 3.1 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.5 CCH59553.1 - 0.021 15.4 2.2 0.021 15.4 2.2 1.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 CCH59553.1 - 0.03 13.7 7.1 0.031 13.6 7.1 1.0 1 0 0 1 1 1 0 FAM76 protein H-kinase_dim PF02895.14 CCH59553.1 - 0.046 14.1 1.1 0.1 13.0 1.1 1.6 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Macoilin PF09726.9 CCH59553.1 - 0.13 10.8 5.0 0.14 10.7 5.0 1.1 1 0 0 1 1 1 0 Macoilin family ABC_tran_CTD PF16326.5 CCH59553.1 - 0.93 9.8 10.3 0.78 10.0 8.1 2.0 2 1 0 2 2 2 0 ABC transporter C-terminal domain ApoO PF09769.9 CCH59555.1 - 1.3e-31 109.3 0.0 1.6e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein O Globin PF00042.22 CCH59556.1 - 6.4e-09 36.4 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.21 CCH59556.1 - 1.8e-08 35.0 0.0 4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CCH59556.1 - 2.4e-08 34.2 0.0 5.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CCH59556.1 - 0.048 13.8 0.1 0.5 10.5 0.1 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Protoglobin PF11563.8 CCH59556.1 - 0.1 12.5 0.3 0.28 11.1 0.3 1.7 1 1 0 1 1 1 0 Protoglobin RTT107_BRCT_6 PF16771.5 CCH59557.1 - 2.9e-37 127.3 5.1 2.9e-37 127.3 5.1 4.7 5 1 1 6 6 6 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CCH59557.1 - 8.3e-23 80.2 0.1 8.3e-23 80.2 0.1 3.7 5 0 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CCH59557.1 - 1e-15 57.4 0.6 3.6e-09 36.4 0.0 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT_2 PF16589.5 CCH59557.1 - 2e-12 47.3 3.1 3.5e-07 30.5 0.1 4.1 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CCH59557.1 - 8.4e-10 38.9 3.1 2.4e-05 24.6 0.2 4.9 7 0 0 7 7 7 2 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 CCH59558.1 - 1.9e-34 118.1 0.4 9.4e-13 48.6 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCH59558.1 - 3.3e-26 91.3 0.5 1.2e-07 32.1 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCH59558.1 - 8.9e-23 80.1 0.1 2e-07 31.2 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH59558.1 - 3e-22 76.3 0.2 0.0088 16.5 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CCH59558.1 - 1.5e-18 66.3 0.3 0.0012 19.2 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat DIE2_ALG10 PF04922.12 CCH59559.1 - 4.1e-110 368.8 29.1 6e-110 368.2 29.1 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family DUF4519 PF15012.6 CCH59559.1 - 0.58 10.4 0.1 0.58 10.4 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Pex24p PF06398.11 CCH59560.1 - 9.4e-56 189.4 10.5 1.2e-55 189.0 10.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.12 CCH59560.1 - 0.0027 17.1 4.7 0.0049 16.3 0.2 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF639) Wzy_C PF04932.15 CCH59560.1 - 0.027 14.1 0.5 0.16 11.6 0.2 2.0 2 0 0 2 2 2 0 O-Antigen ligase Reticulon PF02453.17 CCH59560.1 - 0.033 14.1 0.7 1.3 9.0 0.1 2.4 2 0 0 2 2 2 0 Reticulon DUF1764 PF08576.10 CCH59560.1 - 3.5 8.6 10.5 0.41 11.6 5.4 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) WD40 PF00400.32 CCH59561.1 - 9.8e-10 38.9 2.3 0.18 12.7 0.3 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59561.1 - 9.7e-06 25.8 0.3 1.3 9.3 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BING4CT PF08149.11 CCH59561.1 - 0.00073 19.3 0.0 0.37 10.6 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain DUF963 PF06131.11 CCH59561.1 - 1.3 8.5 9.1 0.32 10.5 2.7 2.5 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ANAPC4_WD40 PF12894.7 CCH59562.1 - 5e-05 23.5 0.7 0.19 12.0 0.0 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH59562.1 - 0.0015 19.4 1.3 0.92 10.5 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Lactonase PF10282.9 CCH59562.1 - 0.008 15.5 0.3 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller CAP_assoc_N PF14504.6 CCH59562.1 - 1.1 9.0 12.8 0.82 9.4 0.7 3.4 2 1 1 3 3 3 0 CAP-associated N-terminal SKG6 PF08693.10 CCH59564.1 - 3.9e-13 48.6 6.4 6.9e-13 47.8 6.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ASFV_J13L PF05568.11 CCH59564.1 - 0.0041 16.9 0.1 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 African swine fever virus J13L protein Adeno_E3_CR2 PF02439.15 CCH59564.1 - 0.03 14.1 3.1 0.051 13.3 3.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cytomega_TRL10 PF06084.11 CCH59564.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF485 PF04341.12 CCH59564.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 EphA2_TM PF14575.6 CCH59564.1 - 0.36 11.7 0.1 0.36 11.7 0.1 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 CCH59564.1 - 1.7 8.6 3.3 7.5 6.6 3.3 2.1 1 1 0 1 1 1 0 Syndecan domain Ribosomal_L6 PF00347.23 CCH59565.1 - 1.2e-26 93.1 1.7 2.6e-12 47.3 0.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.22 CCH59566.1 - 4.9e-16 58.7 2.1 4.9e-14 52.1 0.8 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 CRM1_C PF08767.11 CCH59567.1 - 9.5e-128 425.9 2.7 9.5e-128 425.9 2.7 3.2 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CCH59567.1 - 5.5e-37 127.1 6.4 5.5e-37 127.1 6.4 3.8 4 1 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CCH59567.1 - 6.5e-32 109.0 1.1 1.7e-31 107.6 1.1 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CCH59567.1 - 1.5e-28 98.6 0.2 1e-27 95.9 0.2 2.6 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CCH59567.1 - 4.1e-14 51.8 0.3 4.1e-14 51.8 0.3 1.9 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CCH59567.1 - 9.8e-14 51.0 0.0 9.8e-14 51.0 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Hemocyanin_M PF00372.19 CCH59567.1 - 0.092 11.9 0.4 0.95 8.6 0.0 2.3 2 0 0 2 2 2 0 Hemocyanin, copper containing domain FNIP_C PF14638.6 CCH59567.1 - 0.38 10.4 8.0 0.031 13.9 1.2 2.5 3 0 0 3 3 3 0 Folliculin-interacting protein C-terminus DUF507 PF04368.13 CCH59567.1 - 0.72 9.8 5.7 1.1 9.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF507) Ferric_reduct PF01794.19 CCH59568.1 - 1.1e-20 74.0 13.2 1.1e-20 74.0 13.2 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CCH59568.1 - 0.0015 18.6 0.2 0.0039 17.3 0.2 1.7 1 0 0 1 1 1 1 FAD-binding domain Defensin_like PF10868.8 CCH59568.1 - 0.025 15.3 0.3 0.058 14.2 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich antifungal protein 2, defensin-like MMR_HSR1_C PF08438.10 CCH59569.1 - 1.1e-36 125.8 0.1 2.2e-36 124.8 0.1 1.5 2 0 0 2 2 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CCH59569.1 - 8.4e-20 71.0 0.0 2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH59569.1 - 4e-07 29.7 0.2 1.1e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CCH59569.1 - 0.00079 19.0 0.1 0.37 10.3 0.1 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCH59569.1 - 0.0064 16.6 0.9 0.049 13.7 0.1 2.6 3 1 1 4 4 4 1 Dynamin family ATP_bind_1 PF03029.17 CCH59569.1 - 0.026 14.3 0.8 5.2 6.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CCH59569.1 - 0.044 13.1 0.7 0.54 9.6 0.2 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CCH59569.1 - 0.075 12.9 0.2 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase KTI12 PF08433.10 CCH59569.1 - 0.075 12.5 0.1 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.27 CCH59569.1 - 0.097 13.2 0.0 0.81 10.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 CCH59569.1 - 0.18 10.8 0.9 1.4 7.8 0.0 2.5 2 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RHD3 PF05879.12 CCH59569.1 - 0.18 9.9 2.0 0.57 8.3 0.3 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) TPP_enzyme_N PF02776.18 CCH59570.1 - 8.9e-31 106.8 0.1 1.5e-30 106.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH59570.1 - 3.9e-28 97.9 0.0 5.2e-27 94.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH59570.1 - 2.4e-12 46.9 0.0 3.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4763 PF15960.5 CCH59571.1 - 0.0012 18.2 11.4 0.042 13.1 11.3 2.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) DUF724 PF05266.14 CCH59571.1 - 0.19 11.5 6.9 0.73 9.6 6.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) NolB PF17398.2 CCH59571.1 - 0.23 11.9 5.8 0.03 14.7 1.2 1.8 2 0 0 2 2 2 0 Nodulation protein NolB Fez1 PF06818.15 CCH59571.1 - 5 7.5 18.3 0.027 14.9 8.4 2.4 2 1 1 3 3 3 0 Fez1 HALZ PF02183.18 CCH59571.1 - 6.1 7.1 14.7 0.23 11.7 0.5 3.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Thioredoxin PF00085.20 CCH59572.1 - 8.7e-29 99.5 0.1 1e-28 99.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CCH59572.1 - 8.4e-07 28.8 0.1 8.8e-06 25.5 0.0 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_2 PF13098.6 CCH59572.1 - 2.9e-06 27.7 0.2 2.2e-05 24.8 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DIM1 PF02966.16 CCH59572.1 - 5.4e-06 26.2 0.0 6.2e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.6 CCH59572.1 - 1.1e-05 25.6 0.1 1.9e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CCH59572.1 - 4.8e-05 23.1 0.0 6.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CCH59572.1 - 0.0008 19.3 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 CCH59572.1 - 0.008 16.0 0.0 0.0098 15.7 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CCH59572.1 - 0.018 15.2 0.1 0.028 14.6 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 CCH59572.1 - 0.035 13.5 0.1 0.038 13.3 0.1 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 CCH59572.1 - 0.078 11.9 0.0 0.082 11.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin DUF2847 PF11009.8 CCH59572.1 - 0.15 11.9 0.0 0.54 10.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2847) HAD PF12710.7 CCH59573.1 - 3.6e-15 56.9 0.0 4.9e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCH59573.1 - 4.1e-15 56.6 0.5 9.5e-15 55.5 0.5 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCH59573.1 - 2.2e-07 30.9 7.2 1.2e-06 28.5 0.1 3.4 2 2 2 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCH59573.1 - 2.6e-05 24.4 7.0 0.028 14.5 1.1 3.0 3 1 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CCH59573.1 - 0.00063 19.2 0.7 0.0019 17.7 0.7 1.7 1 1 0 1 1 1 1 Putative Phosphatase S6PP PF05116.13 CCH59573.1 - 0.059 12.9 0.1 0.57 9.7 0.0 2.5 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase BmKX PF09132.10 CCH59573.1 - 0.061 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 BmKX Ribosomal_L7Ae PF01248.26 CCH59573.1 - 0.33 10.7 3.0 13 5.6 0.4 3.0 2 1 1 3 3 3 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Acid_PPase PF12689.7 CCH59573.1 - 0.36 10.7 2.9 1.6 8.5 0.2 2.8 2 1 0 2 2 2 0 Acid Phosphatase Mvb12 PF09452.10 CCH59574.1 - 2.7e-34 117.4 0.5 3.2e-34 117.2 0.5 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 Aldolase_II PF00596.21 CCH59575.1 - 1.6e-43 148.8 0.0 1.9e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Mer2 PF09074.10 CCH59576.1 - 1e-49 169.0 16.3 1e-49 169.0 16.3 1.7 2 0 0 2 2 2 1 Mer2 DUF3656 PF12392.8 CCH59576.1 - 0.035 14.7 2.1 0.076 13.7 1.9 2.0 1 1 0 1 1 1 0 Collagenase YabA PF06156.13 CCH59576.1 - 0.079 13.6 10.2 0.055 14.1 3.3 2.7 2 1 0 2 2 2 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 CCH59576.1 - 1.1 9.5 15.6 0.12 12.5 9.4 2.1 2 0 0 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.9 CCH59576.1 - 1.3 9.0 17.9 0.35 10.9 12.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CCH59576.1 - 2.9 7.9 10.0 0.86 9.7 3.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DNA_repr_REX1B PF14966.6 CCH59576.1 - 3.9 8.2 8.0 5.3 7.8 3.4 3.1 1 1 0 2 2 2 0 DNA repair REX1-B Phage_GPO PF05929.11 CCH59576.1 - 4.1 7.0 7.6 3.4 7.2 5.9 1.6 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FTHFS PF01268.19 CCH59577.1 - 4.6e-249 827.2 1.4 6e-249 826.9 1.4 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCH59577.1 - 1.7e-53 180.2 0.6 1.7e-53 180.2 0.6 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCH59577.1 - 7.3e-36 123.0 1.3 1.5e-35 121.9 1.3 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 CCH59577.1 - 0.061 13.4 0.4 1.5 8.9 0.1 2.9 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rhodanese PF00581.20 CCH59578.1 - 1.4e-11 44.8 0.1 1.8e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rotamase PF00639.21 CCH59579.1 - 3.5e-26 92.0 0.2 6.5e-26 91.1 0.2 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CCH59579.1 - 7.9e-20 71.5 0.0 1.2e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CCH59579.1 - 6.2e-09 35.8 1.8 1.2e-08 34.8 1.8 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CCH59579.1 - 3e-06 28.1 0.0 7.5e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF4660 PF15559.6 CCH59579.1 - 0.076 13.3 3.6 0.11 12.8 3.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4660) CTP_transf_like PF01467.26 CCH59580.1 - 1.8e-33 115.7 0.1 5.9e-33 114.1 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase-like Trefoil PF00088.18 CCH59580.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Trefoil (P-type) domain Apt1 PF10351.9 CCH59580.1 - 1.1 8.1 38.7 0.43 9.4 10.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain PMT PF02366.18 CCH59581.1 - 4.8e-83 278.5 22.8 4.8e-83 278.5 22.8 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCH59581.1 - 5.9e-51 172.9 18.1 5.9e-51 172.9 18.1 2.4 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCH59581.1 - 1.5e-19 70.6 0.0 2.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF3533 PF12051.8 CCH59582.1 - 7.6e-119 397.0 17.5 1.2e-118 396.3 17.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Spot_14 PF07084.12 CCH59582.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 MFS_1 PF07690.16 CCH59584.1 - 2e-23 82.9 39.9 3.7e-23 82.0 39.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans PF05007.13 CCH59585.1 - 2.4e-78 263.6 29.7 2.4e-78 263.6 29.7 2.2 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CCH59585.1 - 4.4e-07 29.3 29.2 1.1e-06 28.0 29.2 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CCH59585.1 - 5.7e-06 26.2 5.2 5.7e-06 26.2 5.2 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 87 SPC12 PF06645.13 CCH59586.1 - 1.5e-24 85.8 0.5 1.8e-24 85.6 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Biotin_lipoyl PF00364.22 CCH59587.1 - 9.9e-21 73.4 0.9 1.9e-20 72.5 0.9 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CCH59587.1 - 5.7e-05 23.4 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain ATP-sulfurylase PF01747.17 CCH59588.1 - 2.5e-87 291.8 0.0 3.2e-87 291.4 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CCH59588.1 - 6.8e-43 146.1 0.0 1.2e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Cytotoxic PF09000.10 CCH59588.1 - 0.017 15.4 0.0 0.059 13.7 0.0 1.8 2 0 0 2 2 2 0 Cytotoxic Gp_dh_C PF02800.20 CCH59589.1 - 4.5e-72 240.8 0.0 7.4e-72 240.1 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCH59589.1 - 3.8e-38 129.9 0.0 1e-37 128.5 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCH59589.1 - 0.014 15.5 1.2 0.028 14.5 0.3 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Memo PF01875.17 CCH59590.1 - 2e-92 309.2 0.1 2.3e-92 309.0 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.12 CCH59591.1 - 6e-38 129.5 0.2 1.2e-37 128.5 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CCH59591.1 - 3.7e-15 56.0 1.4 8.6e-15 54.8 1.4 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DUF1415 PF07209.12 CCH59591.1 - 0.11 12.3 0.2 0.26 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) AA_permease PF00324.21 CCH59592.1 - 1.7e-137 458.9 34.2 2.1e-137 458.6 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH59592.1 - 4.1e-36 124.7 35.0 5.2e-36 124.4 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease NAP PF00956.18 CCH59593.1 - 6.2e-88 294.5 10.3 6.2e-88 294.5 10.3 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ribul_P_3_epim PF00834.19 CCH59594.1 - 9e-68 227.6 0.0 1.2e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CCH59594.1 - 0.051 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF1687 PF07955.11 CCH59595.1 - 5.6e-23 81.8 0.7 7e-23 81.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) zf-H2C2 PF09337.10 CCH59596.1 - 6.8e-14 51.8 1.3 1.4e-13 50.8 1.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 CCH59596.1 - 9.9e-11 41.6 0.3 2.4e-10 40.4 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CCH59596.1 - 5.4e-07 29.9 0.0 2.1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CedA PF10729.9 CCH59596.1 - 0.0022 17.8 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 Cell division activator CedA Acetyltransf_3 PF13302.7 CCH59596.1 - 0.0094 16.6 0.0 0.024 15.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF832 PF05734.11 CCH59596.1 - 0.089 12.3 0.2 0.17 11.4 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Acetyltransf_CG PF14542.6 CCH59596.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Macoilin PF09726.9 CCH59596.1 - 2.4 6.6 48.9 0.041 12.5 10.8 2.3 2 0 0 2 2 2 0 Macoilin family DUF5310 PF17237.2 CCH59597.1 - 1.6e-19 69.5 0.4 2.1e-19 69.1 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5310) TrkH PF02386.16 CCH59598.1 - 4.1e-165 550.0 0.5 3e-163 543.9 0.0 2.2 2 0 0 2 2 2 2 Cation transport protein Sigma70_ner PF04546.13 CCH59598.1 - 0.0046 16.9 13.0 0.0046 16.9 13.0 3.7 2 1 0 3 3 3 1 Sigma-70, non-essential region Presenilin PF01080.17 CCH59598.1 - 0.0081 15.0 0.3 0.0081 15.0 0.3 3.9 3 1 0 3 3 3 1 Presenilin Connexin PF00029.19 CCH59598.1 - 5 6.8 12.7 0.022 14.5 0.6 3.1 3 0 0 3 3 3 0 Connexin CPSase_L_D2 PF02786.17 CCH59599.1 - 1e-112 374.8 0.7 1.7e-84 282.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CCH59599.1 - 5.7e-49 165.2 0.0 1.3e-48 164.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CCH59599.1 - 4.6e-46 157.0 0.0 1.1e-45 155.8 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 CCH59599.1 - 5.3e-46 156.3 0.0 1.1e-45 155.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 CCH59599.1 - 1.1e-39 135.5 0.5 3.4e-39 134.0 0.2 2.0 2 0 0 2 2 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CCH59599.1 - 2.7e-32 112.0 2.1 3.6e-32 111.6 0.4 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CCH59599.1 - 1.8e-18 66.5 0.0 2e-17 63.2 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CCH59599.1 - 2.8e-16 59.7 2.7 1.2e-08 34.8 0.4 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCH59599.1 - 4.3e-15 55.7 0.5 1.2e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCH59599.1 - 4e-10 39.5 0.0 7.7e-05 22.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CCH59599.1 - 1.3e-05 25.1 0.1 0.00066 19.5 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 CCH59599.1 - 0.00032 20.8 1.2 0.73 9.9 0.2 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 CCH59599.1 - 0.00035 20.4 1.0 0.048 13.5 0.0 4.2 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 CCH59599.1 - 0.013 15.3 0.6 6.9 6.4 0.1 2.9 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain mIF3 PF14877.6 CCH59600.1 - 1.5e-49 168.1 15.0 1.5e-49 168.1 15.0 2.3 2 0 0 2 2 2 1 Mitochondrial translation initiation factor SH3_1 PF00018.28 CCH59600.1 - 0.19 11.4 0.9 0.49 10.0 0.1 2.1 2 0 0 2 2 2 0 SH3 domain Solute_trans_a PF03619.16 CCH59601.1 - 1.3e-70 238.0 23.8 1.6e-70 237.7 23.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Mito_carr PF00153.27 CCH59602.1 - 4.7e-61 202.8 3.9 1.7e-22 79.2 0.3 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCH59602.1 - 0.0014 17.9 1.3 0.1 11.7 0.1 2.7 2 1 0 2 2 2 2 Gammaproteobacterial serine protease XPG_N PF00752.17 CCH59603.1 - 3.7e-35 120.4 0.1 1.3e-34 118.7 0.1 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCH59603.1 - 2.2e-24 85.6 0.0 1.7e-23 82.8 0.0 2.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCH59603.1 - 0.0023 18.5 6.0 0.016 15.8 0.0 3.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Mito_carr PF00153.27 CCH59605.1 - 8.1e-58 192.4 5.0 5.8e-20 71.0 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Ctr PF04145.15 CCH59606.1 - 4.6e-19 69.5 10.9 1.5e-17 64.6 10.9 2.0 1 1 0 1 1 1 1 Ctr copper transporter family DUF2897 PF11446.8 CCH59606.1 - 0.1 12.5 1.0 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) RhoGAP PF00620.27 CCH59607.1 - 2.5e-09 37.1 1.5 1.2e-08 34.9 0.3 2.5 2 0 0 2 2 2 1 RhoGAP domain Fungal_trans PF04082.18 CCH59608.1 - 4.8e-25 88.1 0.2 1.1e-24 86.9 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH59608.1 - 6.5e-08 32.6 13.5 1.2e-07 31.7 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG7_N PF16420.5 CCH59609.1 - 1.2e-47 163.1 1.8 1.7e-47 162.5 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CCH59609.1 - 7.8e-46 156.4 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 CCH59609.1 - 0.0094 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CCH59609.1 - 0.032 14.3 0.0 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NOP19 PF10863.8 CCH59610.1 - 3.6e-55 185.7 7.5 3.6e-55 185.7 7.5 1.9 1 1 1 2 2 2 1 Nucleolar protein 19 DUF3245 PF11595.8 CCH59610.1 - 0.044 14.3 16.7 2.6 8.5 12.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) DEAD PF00270.29 CCH59611.1 - 2.9e-42 144.4 0.0 5.3e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59611.1 - 1.9e-30 105.5 0.0 1.6e-29 102.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59611.1 - 0.0013 18.7 0.0 0.0033 17.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit THP2 PF09432.10 CCH59612.1 - 5.4e-51 172.0 7.0 5.4e-51 172.0 7.0 1.9 2 1 0 2 2 2 1 Tho complex subunit THP2 ATP-synt_E_2 PF08112.11 CCH59612.1 - 0.0045 17.2 1.0 0.0045 17.2 1.0 3.5 4 2 0 4 4 4 1 ATP synthase epsilon subunit DUF948 PF06103.11 CCH59612.1 - 0.034 14.4 4.2 0.15 12.3 0.3 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0449 PF15136.6 CCH59612.1 - 0.46 11.0 0.1 0.46 11.0 0.1 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0449 Mistic PF11458.8 CCH59612.1 - 0.73 9.8 12.8 0.72 9.9 1.3 2.7 3 0 0 3 3 3 0 Membrane-integrating protein Mistic FapA PF03961.13 CCH59612.1 - 3.4 6.2 15.4 0.018 13.7 1.4 2.6 1 1 2 3 3 3 0 Flagellar Assembly Protein A RBD-FIP PF09457.10 CCH59612.1 - 7.9 6.5 17.8 0.53 10.2 1.8 3.8 4 1 0 4 4 4 0 FIP domain ANAPC8 PF04049.13 CCH59613.1 - 4e-43 146.8 7.4 1.1e-42 145.4 3.5 3.0 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 CCH59613.1 - 1.9e-24 84.4 15.4 2.1e-05 24.1 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59613.1 - 1.1e-21 75.2 19.4 3.6e-05 23.6 0.0 9.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 CCH59613.1 - 4.8e-19 66.9 14.8 0.00076 19.4 0.0 8.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CCH59613.1 - 4.6e-15 55.0 0.1 0.00092 19.8 0.0 5.5 4 2 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH59613.1 - 5.9e-12 45.1 11.1 1.4e-08 34.2 0.0 5.3 4 2 2 6 6 5 2 TPR repeat TPR_16 PF13432.6 CCH59613.1 - 3.4e-09 37.2 0.5 6.1e-06 26.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59613.1 - 1e-07 32.1 11.0 0.0049 17.1 0.1 5.6 3 1 5 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCH59613.1 - 1.3e-07 31.5 11.2 0.0048 17.2 0.0 7.2 9 0 0 9 9 6 1 Tetratricopeptide repeat ChAPs PF09295.10 CCH59613.1 - 3.5e-07 29.6 0.2 6.5e-05 22.1 0.0 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 CCH59613.1 - 1.6e-06 27.7 2.5 1.1 9.5 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH59613.1 - 4.2e-05 23.7 21.0 0.0021 18.3 0.1 5.4 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CCH59613.1 - 5.2e-05 23.7 3.1 2.1 8.9 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CCH59613.1 - 0.00014 21.2 0.6 0.62 9.2 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCH59613.1 - 0.00015 22.2 3.3 19 6.1 0.0 6.6 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCH59613.1 - 0.0085 16.2 0.2 1.1 9.4 0.1 2.6 1 1 3 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 CCH59613.1 - 0.019 15.4 0.1 0.075 13.5 0.0 1.9 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 CCH59613.1 - 0.046 13.6 2.0 15 5.7 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 CCH59613.1 - 0.33 11.0 9.5 13 5.9 0.1 5.0 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Exonuc_VII_S PF02609.16 CCH59613.1 - 5.8 7.1 6.1 13 6.0 0.3 3.9 4 1 1 5 5 4 0 Exonuclease VII small subunit PROCN PF08083.11 CCH59614.1 - 2.1e-221 734.9 13.1 3.5e-221 734.1 13.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CCH59614.1 - 8.2e-120 398.6 1.0 2.1e-119 397.3 1.0 1.8 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CCH59614.1 - 6.7e-84 279.6 1.5 6.7e-84 279.6 1.5 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CCH59614.1 - 2.2e-79 264.7 4.8 4.6e-79 263.6 4.8 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CCH59614.1 - 5.3e-71 237.0 0.1 1.4e-70 235.6 0.1 1.8 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CCH59614.1 - 9.5e-45 150.9 0.7 2.5e-44 149.5 0.7 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CCH59614.1 - 1.6e-43 147.5 0.0 4e-43 146.3 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 CCH59614.1 - 0.014 15.4 0.3 0.045 13.7 0.1 2.0 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPD PF14811.6 CCH59614.1 - 0.039 13.8 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif T4_Rnl2_C PF18043.1 CCH59615.1 - 0.037 14.2 0.3 0.13 12.5 0.3 1.9 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal mCpol PF18182.1 CCH59615.1 - 0.14 12.5 0.4 0.32 11.4 0.4 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Dna2 PF08696.11 CCH59616.1 - 1.8e-54 184.6 2.1 3.3e-54 183.8 0.8 2.3 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.6 CCH59616.1 - 5.2e-47 160.1 1.1 1.8e-46 158.3 1.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCH59616.1 - 6.1e-32 111.4 8.9 1.7e-16 60.8 0.0 4.8 3 1 1 4 4 4 2 AAA domain AAA_30 PF13604.6 CCH59616.1 - 1.3e-13 51.1 0.0 2.7e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH59616.1 - 2.2e-12 47.5 0.0 5.1e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 CCH59616.1 - 1.4e-07 31.7 0.0 2.4e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 CCH59616.1 - 2.4e-05 24.2 0.0 0.95 9.1 0.1 3.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CCH59616.1 - 0.00015 21.7 0.0 0.0005 20.0 0.0 2.0 1 0 0 1 1 1 1 Helicase SRP54 PF00448.22 CCH59616.1 - 0.019 14.6 0.1 0.055 13.1 0.1 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CCH59616.1 - 0.02 15.3 0.0 0.057 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Cas_Cas4 PF01930.17 CCH59616.1 - 0.045 13.9 0.1 0.28 11.3 0.1 2.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 AAA_29 PF13555.6 CCH59616.1 - 0.048 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CCH59616.1 - 0.071 13.5 0.0 0.3 11.5 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CCH59616.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.6 CCH59616.1 - 0.12 13.0 0.5 1.6 9.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 CCH59616.1 - 0.12 12.4 1.2 0.36 10.9 0.6 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 CCH59616.1 - 0.14 12.4 0.2 1.6 9.0 0.1 2.9 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 CCH59616.1 - 0.69 9.9 7.9 0.19 11.7 0.1 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RRM_1 PF00076.22 CCH59617.1 - 3.6e-35 119.6 0.2 1.2e-15 57.0 0.0 5.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCH59617.1 - 0.00056 19.9 0.0 0.024 14.7 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif SET_assoc PF11767.8 CCH59617.1 - 0.033 13.8 0.0 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated CPDase PF07823.11 CCH59618.1 - 6.6e-73 244.6 0.4 2e-72 243.1 0.4 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CCH59618.1 - 0.0015 18.5 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily TFIIB PF00382.19 CCH59619.1 - 9.6e-48 160.1 6.3 2e-23 82.2 0.5 2.7 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CCH59619.1 - 1.7e-30 105.3 2.6 3.7e-30 104.2 2.6 1.6 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CCH59619.1 - 1.7e-10 40.2 2.4 3.2e-10 39.3 2.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CCH59619.1 - 0.0023 17.7 0.2 0.36 10.6 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 CCH59619.1 - 0.088 12.8 0.2 0.088 12.8 0.2 3.2 3 0 0 3 3 3 0 Transcription factor IIB C-terminal module 1 SNF2_N PF00176.23 CCH59620.1 - 2.9e-57 194.0 0.3 4.6e-57 193.3 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CCH59620.1 - 3.7e-46 157.6 0.4 3.7e-46 157.6 0.4 2.7 3 0 0 3 3 3 1 Rad54 N terminal Helicase_C PF00271.31 CCH59620.1 - 1.6e-16 60.6 0.0 5.5e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59620.1 - 7.1e-09 35.9 0.2 7e-07 29.4 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCH59620.1 - 1.5e-06 27.6 0.3 1.5e-06 27.6 0.3 3.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Presenilin PF01080.17 CCH59620.1 - 2 7.1 5.5 3.1 6.5 5.5 1.3 1 0 0 1 1 1 0 Presenilin Ig_4 PF16680.5 CCH59620.1 - 9.5 6.6 9.4 3.8 7.9 2.2 3.4 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain TBP PF00352.21 CCH59621.1 - 2.4e-68 226.1 0.1 6.8e-33 112.5 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CCH59621.1 - 2e-05 24.6 0.1 0.25 11.5 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CCH59621.1 - 0.033 14.0 0.2 0.26 11.1 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ATPase PF06745.13 CCH59622.1 - 2.2e-07 30.5 0.0 3.8e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 CCH59622.1 - 0.00055 19.9 2.9 0.00055 19.9 2.9 1.9 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Rad51 PF08423.11 CCH59622.1 - 0.0021 17.4 0.0 0.0043 16.4 0.0 1.5 1 1 0 1 1 1 1 Rad51 AAA PF00004.29 CCH59622.1 - 0.0042 17.5 0.0 0.015 15.7 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.21 CCH59622.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 CCH59622.1 - 0.062 13.9 2.6 1.4 9.5 0.5 3.0 2 1 0 2 2 2 0 AAA domain HypA PF01155.19 CCH59623.1 - 0.02 14.9 1.4 0.02 14.9 1.4 3.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0547 PF10571.9 CCH59623.1 - 3.5 7.8 13.2 11 6.2 0.4 4.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DnaJ_CXXCXGXG PF00684.19 CCH59623.1 - 4.4 7.7 21.7 0.38 11.1 7.5 4.0 2 2 0 2 2 2 0 DnaJ central domain Aminotran_1_2 PF00155.21 CCH59624.1 - 9.3e-17 61.2 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CCH59624.1 - 0.074 11.8 0.0 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase UPF0160 PF03690.13 CCH59625.1 - 2.3e-128 428.3 0.0 2.6e-128 428.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Cofilin_ADF PF00241.20 CCH59626.1 - 2.7e-22 78.8 0.1 3.5e-22 78.5 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GDI PF00996.18 CCH59627.1 - 2.7e-226 751.2 0.8 3.1e-226 750.9 0.8 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CCH59627.1 - 0.0039 17.4 0.0 0.0076 16.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain LSM PF01423.22 CCH59628.1 - 1.3e-18 66.4 0.2 1.6e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCH59628.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein zf-C2H2_10 PF16588.5 CCH59629.1 - 2.7e-11 43.0 5.8 4.8e-11 42.2 5.8 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 CCH59629.1 - 0.031 14.4 2.3 0.048 13.7 2.3 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF1041 PF06292.17 CCH59629.1 - 0.19 12.1 3.0 0.57 10.6 3.0 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1041) Phage_min_cap2 PF06152.11 CCH59629.1 - 0.44 9.4 3.5 0.5 9.2 3.5 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 MCM PF00493.23 CCH59630.1 - 1.6e-102 341.4 0.0 2.6e-102 340.7 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCH59630.1 - 1.5e-35 121.8 0.0 2.5e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCH59630.1 - 1.5e-25 89.5 0.2 3e-25 88.4 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 CCH59630.1 - 4.4e-23 82.3 32.6 4.4e-23 82.3 32.6 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CCH59630.1 - 5.6e-11 42.9 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCH59630.1 - 2.7e-09 36.7 0.0 2.6e-07 30.2 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCH59630.1 - 1.8e-07 31.2 0.0 4.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCH59630.1 - 0.00053 19.9 0.0 0.0024 17.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCH59630.1 - 0.002 17.9 0.1 0.016 14.9 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CCH59630.1 - 0.024 15.0 0.0 0.074 13.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCH59630.1 - 0.059 13.1 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain SelR PF01641.18 CCH59630.1 - 0.067 13.3 0.1 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 SelR domain Aldedh PF00171.22 CCH59631.1 - 5.9e-39 133.9 0.0 3.5e-24 85.1 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family CBFD_NFYB_HMF PF00808.23 CCH59632.1 - 2.6e-24 85.3 0.0 3.5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCH59632.1 - 0.00013 22.3 0.1 0.00023 21.5 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CCH59632.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 CCH59632.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-X PF09415.10 CCH59632.1 - 0.046 14.0 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X CCDC24 PF15669.5 CCH59632.1 - 0.19 11.6 6.5 0.21 11.5 2.6 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family RVT_2 PF07727.14 CCH59633.1 - 7.7e-18 65.0 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EcoRII-N PF09217.10 CCH59633.1 - 0.019 14.7 0.1 0.019 14.7 0.1 1.7 2 0 0 2 2 2 0 Restriction endonuclease EcoRII, N-terminal Tubulin-binding PF00418.19 CCH59634.1 - 0.044 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat LAM_C PF12544.8 CCH59634.1 - 1.1 9.4 4.7 2.2 8.4 0.3 2.9 3 0 0 3 3 3 0 Lysine-2,3-aminomutase gag_pre-integrs PF13976.6 CCH59635.1 - 9.1e-07 28.7 0.9 8e-06 25.6 0.1 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain DHBP_synthase PF00926.19 CCH59636.1 - 1.1e-80 269.8 0.0 1.2e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF4531 PF15041.6 CCH59637.1 - 0.034 14.3 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) PQQ_3 PF13570.6 CCH59637.1 - 0.04 14.4 0.2 0.73 10.4 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain WD40 PF00400.32 CCH59637.1 - 0.45 11.5 3.4 0.62 11.0 0.5 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat SLD5_C PF16922.5 CCH59638.1 - 1.9e-19 69.6 0.1 3.9e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CCH59638.1 - 3.1e-06 27.6 0.6 1.1e-05 25.8 0.6 2.0 2 1 0 2 2 2 1 GINS complex protein Peptidase_M16_C PF05193.21 CCH59639.1 - 7.6e-13 48.9 0.0 1.6e-11 44.6 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCH59639.1 - 8.8e-09 35.5 0.0 3.6e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF2833 PF11090.8 CCH59639.1 - 0.092 13.1 0.3 36 4.8 0.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2833) DUF2312 PF10073.9 CCH59639.1 - 0.15 11.7 9.0 1.5 8.5 2.5 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) Pkinase PF00069.25 CCH59640.1 - 5.8e-64 216.0 0.3 1.6e-63 214.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59640.1 - 7.7e-33 113.9 0.0 1.4e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59640.1 - 5.4e-08 32.5 0.0 2.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCH59640.1 - 0.00084 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCH59640.1 - 0.0044 16.7 1.6 0.54 9.8 0.2 2.9 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCH59640.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HlyIII PF03006.20 CCH59641.1 - 2.1e-47 161.7 10.3 2.5e-47 161.5 10.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related MHYT PF03707.16 CCH59641.1 - 0.62 10.3 3.3 2.9 8.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat BBP1_C PF15272.6 CCH59642.1 - 0.032 14.0 0.2 0.038 13.8 0.2 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PTS_2-RNA PF01885.16 CCH59643.1 - 3e-52 177.3 0.6 4.2e-52 176.8 0.6 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF2660 PF10859.8 CCH59643.1 - 0.12 12.8 2.0 1.8 9.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) CspB_prodomain PF18425.1 CCH59644.1 - 0.026 14.5 0.1 0.084 12.9 0.1 1.9 1 0 0 1 1 1 0 Csp protease B prodomain Vps39_2 PF10367.9 CCH59645.1 - 0.014 15.9 0.7 0.49 10.9 0.1 3.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Sugar_tr PF00083.24 CCH59646.1 - 5.4e-135 450.8 30.5 6.5e-135 450.5 30.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59646.1 - 4.7e-30 104.7 34.0 2e-27 96.0 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH59646.1 - 0.00041 18.9 5.5 0.00041 18.9 5.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCH59646.1 - 0.0088 14.5 0.6 0.0088 14.5 0.6 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector Sec20 PF03908.13 CCH59647.1 - 4.5e-30 103.4 3.1 4.5e-30 103.4 3.1 2.3 2 1 0 2 2 2 1 Sec20 TTRAP PF14203.6 CCH59647.1 - 0.34 10.9 4.4 1.1 9.3 0.6 3.1 2 1 1 3 3 3 0 Putative tranposon-transfer assisting protein ERG4_ERG24 PF01222.17 CCH59648.1 - 7.7e-144 479.6 19.3 8.6e-144 479.5 19.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CCH59648.1 - 2.8e-06 27.0 1.6 2.8e-06 27.0 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) GIDA PF01134.22 CCH59649.1 - 0.072 12.2 2.0 0.082 12.0 2.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A RVT_2 PF07727.14 CCH59650.1 - 4e-18 66.0 1.9 6.4e-18 65.3 0.4 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CCH59650.1 - 0.0034 16.9 0.0 0.0099 15.4 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Aha1_N PF09229.11 CCH59651.1 - 2.5e-27 95.8 0.2 2.9e-27 95.5 0.2 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.11 CCH59652.1 - 4.7e-39 134.0 0.4 5.8e-39 133.7 0.4 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.19 CCH59653.1 - 1e-09 38.4 9.9 3.3e-09 36.8 9.9 1.9 1 0 0 1 1 1 1 WSC domain Pox_A14 PF05767.12 CCH59653.1 - 0.0085 16.2 0.1 0.027 14.6 0.1 1.9 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 SKG6 PF08693.10 CCH59653.1 - 0.038 13.4 1.3 0.13 11.7 1.3 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 CCH59653.1 - 0.2 11.5 6.0 0.73 9.6 6.0 2.0 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_C PF00043.25 CCH59654.1 - 2.1e-10 40.7 0.0 3e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCH59654.1 - 2e-07 31.2 0.0 4.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCH59654.1 - 0.00031 20.9 0.0 0.00057 20.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH59654.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1751 PF08551.10 CCH59655.1 - 4.1e-19 69.0 3.2 4.1e-19 69.0 3.2 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) ADH_zinc_N PF00107.26 CCH59656.1 - 3.2e-11 43.3 0.0 5.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH59656.1 - 8.8e-06 25.6 0.2 3.1e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCH59656.1 - 0.058 14.4 0.1 0.15 13.1 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase HLH PF00010.26 CCH59657.1 - 0.00037 20.4 0.4 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Adaptin_N PF01602.20 CCH59658.1 - 7.6e-114 381.1 17.0 9.6e-114 380.8 17.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CCH59658.1 - 1.5e-49 168.0 3.9 5.6e-49 166.1 3.9 2.1 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CCH59658.1 - 6.7e-30 103.6 0.1 1.8e-29 102.2 0.1 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CCH59658.1 - 3.8e-10 40.0 0.4 4.7e-06 26.9 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CCH59658.1 - 2.1e-06 27.8 12.1 0.0025 17.9 0.3 4.3 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCH59658.1 - 0.011 15.9 2.9 3.4 8.2 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 CCH59658.1 - 0.22 12.1 0.2 3.2 8.3 0.1 3.0 2 1 0 2 2 2 0 HEAT-like repeat Cyclin_N PF00134.23 CCH59659.1 - 2.5e-17 62.8 0.1 3.9e-17 62.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCH59659.1 - 3.7e-06 27.4 0.0 5.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin AAA PF00004.29 CCH59660.1 - 7.7e-18 65.2 0.0 1.4e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CCH59660.1 - 1.6e-16 60.5 0.1 3.7e-13 49.6 0.0 2.6 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CCH59660.1 - 1.7e-15 57.2 0.2 6.6e-15 55.3 0.0 2.2 2 1 1 3 3 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CCH59660.1 - 3.3e-07 30.4 0.0 2.5e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CCH59660.1 - 4.6e-07 30.1 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 CCH59660.1 - 4.5e-06 26.5 0.0 1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCH59660.1 - 8.1e-06 26.3 0.0 1.8e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 CCH59660.1 - 8.6e-06 25.6 0.4 1.6e-05 24.7 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 CCH59660.1 - 1e-05 25.5 0.1 2.2e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCH59660.1 - 1.7e-05 24.8 0.0 6e-05 23.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CCH59660.1 - 2.8e-05 24.4 0.3 0.24 11.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 CCH59660.1 - 4.6e-05 22.7 0.0 5.9e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 CCH59660.1 - 0.00012 22.1 0.0 0.033 14.2 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCH59660.1 - 0.00017 21.4 0.0 0.00087 19.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CCH59660.1 - 0.00052 19.8 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCH59660.1 - 0.00064 19.3 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 CCH59660.1 - 0.00069 19.6 0.2 0.0048 16.9 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CCH59660.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CCH59660.1 - 0.0014 19.2 0.1 0.0042 17.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 CCH59660.1 - 0.0023 18.3 0.1 0.13 12.6 0.0 2.3 1 1 1 2 2 2 1 AAA domain DEAD PF00270.29 CCH59660.1 - 0.0038 17.0 0.1 0.021 14.6 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 CCH59660.1 - 0.0042 16.9 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CCH59660.1 - 0.0042 16.9 0.0 0.0095 15.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CCH59660.1 - 0.012 15.0 0.0 0.084 12.2 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 CCH59660.1 - 0.014 15.0 0.1 0.28 10.8 0.0 2.3 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CCH59660.1 - 0.033 13.8 0.1 0.56 9.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCH59660.1 - 0.035 14.5 0.0 0.075 13.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.23 CCH59660.1 - 0.044 12.5 0.0 0.073 11.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_28 PF13521.6 CCH59660.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCH59660.1 - 0.06 12.6 0.1 0.13 11.5 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Methyltransf_31 PF13847.6 CCH59660.1 - 0.07 12.9 0.7 0.2 11.4 0.7 1.8 1 1 0 1 1 1 0 Methyltransferase domain TniB PF05621.11 CCH59660.1 - 0.072 12.5 0.0 2.1 7.7 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 CCH59660.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCH59660.1 - 0.32 11.5 2.9 1.3 9.5 2.9 2.2 1 1 0 1 1 1 0 AAA domain Mid1 PF12929.7 CCH59661.1 - 1.3e-112 377.2 15.5 1.5e-112 376.9 15.5 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CCH59661.1 - 0.0077 16.8 5.9 0.21 12.2 5.9 2.6 1 1 0 1 1 1 1 Fz domain Erf4 PF10256.9 CCH59662.1 - 1.6e-32 112.1 0.1 2e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Get5_bdg PF16843.5 CCH59663.1 - 3.1e-26 90.6 0.8 9.4e-26 89.1 0.4 1.9 2 0 0 2 2 2 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Get5_C PF18514.1 CCH59663.1 - 2.3e-13 49.6 0.3 6e-13 48.3 0.3 1.8 1 0 0 1 1 1 1 Get5 C-terminal domain ubiquitin PF00240.23 CCH59663.1 - 5.6e-08 32.4 3.2 6.2e-08 32.3 0.8 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CCH59663.1 - 4.3e-05 23.6 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 CCH59663.1 - 0.00071 19.9 6.8 0.00072 19.9 1.4 2.1 1 1 1 2 2 2 1 Blt1 N-terminal domain Pox_MCEL PF03291.16 CCH59663.1 - 0.037 13.2 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme DUF2407 PF10302.9 CCH59663.1 - 0.1 13.1 0.2 0.18 12.3 0.2 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain RabGAP-TBC PF00566.18 CCH59664.1 - 2.8e-41 141.5 7.1 1.9e-32 112.7 0.3 4.4 4 1 0 5 5 5 2 Rab-GTPase-TBC domain YL1 PF05764.13 CCH59664.1 - 0.022 14.9 3.6 0.054 13.6 3.6 1.6 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.6 CCH59664.1 - 6.8 7.1 7.7 43 4.6 7.7 2.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PalH PF08733.10 CCH59665.1 - 1.5e-75 254.3 18.8 1.5e-75 254.3 18.8 1.9 2 0 0 2 2 2 1 PalH/RIM21 DUF3381 PF11861.8 CCH59665.1 - 0.82 9.4 11.1 3.7 7.3 11.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) Pet20 PF08692.10 CCH59666.1 - 2e-25 90.0 0.4 5.7e-25 88.5 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial protein Pet20 Pkinase PF00069.25 CCH59667.1 - 1.3e-64 218.1 0.2 1.3e-64 218.1 0.2 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59667.1 - 6.8e-51 173.0 0.0 1.4e-50 172.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCH59667.1 - 7.6e-23 80.6 0.2 7.6e-23 80.6 0.2 2.7 3 0 0 3 3 3 1 P21-Rho-binding domain PH PF00169.29 CCH59667.1 - 3.4e-10 40.4 0.5 7.4e-10 39.3 0.5 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CCH59667.1 - 5.6e-06 25.9 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCH59667.1 - 1.1e-05 24.4 0.0 1.1e-05 24.4 0.0 3.2 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCH59667.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family NTP_transf_2 PF01909.23 CCH59668.1 - 5.6e-16 58.6 0.1 1.3e-15 57.5 0.1 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CCH59668.1 - 1.3e-13 50.9 0.0 2.6e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CCH59668.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase GCR1_C PF12550.8 CCH59669.1 - 5.1e-23 81.2 0.1 9.8e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Tmemb_170 PF10190.9 CCH59670.1 - 7.5 7.0 9.0 1.4 9.3 5.1 1.8 2 0 0 2 2 2 0 Putative transmembrane protein 170 Redoxin PF08534.10 CCH59672.1 - 2.4e-22 79.2 0.0 2.8e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CCH59672.1 - 4.8e-08 33.0 0.0 6.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Nramp PF01566.18 CCH59673.1 - 1.8e-87 293.7 23.2 3.8e-52 177.4 4.0 2.8 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein RRM_1 PF00076.22 CCH59674.1 - 7.3e-33 112.2 1.7 9e-17 60.7 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH59674.1 - 9.5e-13 48.1 0.3 2.5e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Glyco_H_20C_C PF18088.1 CCH59674.1 - 0.002 18.0 3.5 0.0036 17.2 3.5 1.4 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Nup35_RRM_2 PF14605.6 CCH59674.1 - 0.015 15.3 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UPF0020 PF01170.18 CCH59675.1 - 8.1e-10 38.7 0.0 2.1e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ras PF00071.22 CCH59676.1 - 2e-25 89.3 0.5 2e-20 73.0 0.2 2.7 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCH59676.1 - 1.9e-14 53.9 0.4 5.9e-09 36.2 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH59676.1 - 0.00017 21.1 0.4 0.00058 19.4 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MCM PF00493.23 CCH59676.1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_16 PF13191.6 CCH59676.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TRM13 PF05206.14 CCH59677.1 - 2.3e-69 233.8 0.3 1e-68 231.7 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 CCH59677.1 - 3.8e-12 45.7 6.3 5.1e-12 45.3 5.0 2.0 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 CCH59677.1 - 2.8e-10 39.9 3.1 8.2e-10 38.4 3.1 1.9 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger NABP PF07990.12 CCH59677.1 - 0.039 13.5 0.5 0.051 13.1 0.5 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Ldh_1_C PF02866.18 CCH59678.1 - 1e-37 129.7 0.0 1.6e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCH59678.1 - 2.1e-36 125.1 0.3 3.2e-36 124.5 0.3 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CCH59678.1 - 0.0034 17.0 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase OCD_Mu_crystall PF02423.15 CCH59678.1 - 0.0039 16.2 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 3Beta_HSD PF01073.19 CCH59678.1 - 0.078 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_Gly3P_dh_N PF01210.23 CCH59678.1 - 0.15 12.1 0.1 0.34 10.9 0.1 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Bax1-I PF01027.20 CCH59679.1 - 1.3e-34 119.8 25.0 1.9e-34 119.3 25.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CCH59679.1 - 0.051 13.1 19.0 0.059 12.9 16.3 2.0 2 0 0 2 2 2 0 Bax inhibitor 1 like Phlebovirus_G1 PF07243.11 CCH59679.1 - 0.47 8.8 2.2 0.67 8.3 2.2 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Pkinase PF00069.25 CCH59680.1 - 5.8e-56 189.8 0.0 7.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59680.1 - 8e-26 90.9 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59680.1 - 4.3e-09 36.1 0.0 6.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCH59680.1 - 0.00012 22.1 0.0 0.01 15.8 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCH59680.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 CCH59680.1 - 0.0075 15.2 0.2 0.13 11.1 0.3 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CCH59680.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0220 PF05255.11 CCH59681.1 - 2.2e-71 238.7 1.0 2.6e-71 238.5 1.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) TPR_14 PF13428.6 CCH59683.1 - 4.1e-08 33.4 0.8 0.18 12.7 0.0 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCH59683.1 - 1.7e-07 30.7 0.2 0.26 11.2 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59683.1 - 1.8e-07 30.8 3.8 0.052 13.8 0.0 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCH59683.1 - 2.8e-07 30.1 0.6 0.013 15.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCH59683.1 - 2.2e-06 28.1 3.1 0.032 14.7 0.0 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH59683.1 - 0.0009 19.5 0.3 0.05 14.0 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59683.1 - 0.0013 19.0 1.4 0.65 10.3 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCH59683.1 - 0.0018 18.9 0.3 2.3 9.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCH59683.1 - 0.0019 17.8 0.0 0.24 11.1 0.0 3.9 3 1 1 4 4 4 2 TPR repeat RPN7 PF10602.9 CCH59683.1 - 0.0019 17.9 1.0 0.089 12.5 0.0 3.4 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_15 PF13429.6 CCH59683.1 - 0.016 14.5 2.4 0.25 10.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH59683.1 - 0.041 13.9 1.8 14 6.0 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 CCH59683.1 - 0.049 13.5 0.5 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_MalT PF17874.1 CCH59683.1 - 0.095 12.1 0.2 2 7.7 0.0 2.3 2 0 0 2 2 2 0 MalT-like TPR region ANAPC3 PF12895.7 CCH59683.1 - 0.26 11.5 2.9 2.4 8.4 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCH59683.1 - 0.63 10.0 3.0 1.7 8.7 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Meiotic_rec114 PF03525.14 CCH59684.1 - 4.8e-08 32.4 6.2 4.8e-08 32.4 6.2 1.6 1 1 1 2 2 2 1 Meiotic recombination protein rec114 ATP11 PF06644.11 CCH59685.1 - 1.9e-84 283.7 1.8 2.2e-84 283.5 1.8 1.0 1 0 0 1 1 1 1 ATP11 protein zf-rbx1 PF12678.7 CCH59686.1 - 1e-23 83.4 13.6 1.6e-23 82.8 13.6 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCH59686.1 - 1.9e-16 59.8 10.6 2.8e-16 59.4 10.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CCH59686.1 - 7e-06 26.3 14.2 0.0003 21.0 14.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCH59686.1 - 0.00036 20.3 12.4 0.0021 17.9 12.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH59686.1 - 0.00079 19.2 3.8 0.00079 19.2 3.8 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCH59686.1 - 0.005 16.6 1.3 0.005 16.6 1.3 2.6 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 CCH59686.1 - 0.18 12.0 8.8 0.86 9.8 9.1 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CCH59686.1 - 0.76 9.7 10.6 1.8 8.5 4.3 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH59686.1 - 1.2 9.4 9.4 0.35 11.1 0.6 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CCH59686.1 - 1.4 8.9 10.0 6.7 6.8 10.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 CCH59686.1 - 2.4 8.6 12.2 27 5.2 12.2 2.3 1 1 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.6 CCH59686.1 - 2.9 8.0 10.1 11 6.2 10.1 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CCH59686.1 - 6.6 6.4 14.9 3.8e+02 0.8 14.9 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Med7 PF05983.11 CCH59687.1 - 3.3e-68 229.5 6.6 4e-68 229.3 6.6 1.1 1 0 0 1 1 1 1 MED7 protein PapD_N PF00345.20 CCH59687.1 - 0.12 12.3 1.7 0.2 11.6 0.8 1.7 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Prefoldin_2 PF01920.20 CCH59687.1 - 6 6.9 12.3 0.089 12.8 2.3 2.7 3 0 0 3 3 3 0 Prefoldin subunit WD40 PF00400.32 CCH59688.1 - 2e-27 94.8 16.3 4.9e-06 27.2 0.8 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59688.1 - 2.5e-14 53.3 0.3 0.0063 16.8 0.0 5.6 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH59688.1 - 1.4e-07 31.6 3.7 2e-05 24.6 2.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CCH59688.1 - 0.001 17.9 1.0 0.94 8.1 0.0 2.8 2 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 CCH59688.1 - 0.0054 16.1 0.3 1.4 8.2 0.2 2.9 1 1 2 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 CCH59688.1 - 0.0065 15.5 0.3 1.8 7.5 0.0 3.7 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5007 PF16398.5 CCH59688.1 - 0.031 14.0 0.2 0.61 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5007) YmzC PF14157.6 CCH59688.1 - 0.16 12.1 0.1 0.7 10.0 0.1 2.1 1 0 0 1 1 1 0 YmzC-like protein COX6B PF02297.17 CCH59689.1 - 3.6e-19 68.7 5.4 4.2e-19 68.5 5.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb MYT1 PF08474.11 CCH59689.1 - 0.067 13.1 0.1 0.067 13.1 0.1 1.0 1 0 0 1 1 1 0 Myelin transcription factor 1 CX9C PF16860.5 CCH59689.1 - 0.091 12.8 1.3 0.15 12.0 1.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RIC1 PF07064.13 CCH59690.1 - 1.1e-21 77.5 2.3 4.1e-18 65.7 1.1 2.3 2 0 0 2 2 2 2 RIC1 NFACT-R_1 PF05670.13 CCH59691.1 - 1.5e-32 112.5 0.0 2.9e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain SRP1_TIP1 PF00660.17 CCH59692.1 - 5.3e-07 29.6 1.7 7e-07 29.3 0.1 2.0 1 1 2 3 3 3 1 Seripauperin and TIP1 family ASPRs PF17641.2 CCH59693.1 - 0.076 13.3 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related CLTH PF10607.9 CCH59694.1 - 7.9e-25 87.5 3.6 7.9e-25 87.5 3.6 2.7 1 1 1 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.27 CCH59695.1 - 5.8e-16 57.8 4.4 1.2e-15 56.7 4.4 1.6 1 0 0 1 1 1 1 GATA zinc finger DRMBL PF07522.14 CCH59696.1 - 2.5e-23 82.4 0.0 6.4e-23 81.0 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Pkinase PF00069.25 CCH59697.1 - 3.8e-49 167.4 0.2 4.7e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59697.1 - 3.2e-16 59.4 0.0 4.4e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CCH59697.1 - 0.0013 18.4 0.2 0.0021 17.7 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WHIM1 PF15612.6 CCH59697.1 - 0.01 15.4 0.1 0.028 14.0 0.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 APH PF01636.23 CCH59697.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPP_enzyme_N PF02776.18 CCH59698.1 - 8e-27 93.9 0.0 1.2e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH59698.1 - 9.7e-21 73.9 0.0 1.6e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH59698.1 - 6.7e-13 48.7 0.0 1.6e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUSP PF06337.12 CCH59698.1 - 0.16 12.6 0.9 0.8 10.4 1.2 2.0 2 0 0 2 2 2 0 DUSP domain zf-C3HC4_3 PF13920.6 CCH59699.1 - 0.49 10.3 7.7 1.2 9.0 4.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.19 CCH59700.1 - 1.6e-24 86.3 11.7 1.9e-24 86.1 11.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 CCH59700.1 - 0.032 15.1 0.5 0.05 14.5 0.5 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Herpes_TK_C PF08465.10 CCH59700.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Ribosomal_L13e PF01294.18 CCH59701.1 - 4.2e-66 222.2 2.1 7.2e-66 221.5 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 CCH59702.1 - 8.4e-33 113.5 0.3 9.5e-33 113.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Uso1_p115_C PF04871.13 CCH59703.1 - 0.0056 17.0 1.2 0.0056 17.0 1.2 2.7 2 1 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DEAD PF00270.29 CCH59704.1 - 1.6e-34 119.2 0.0 3.2e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59704.1 - 4.2e-28 97.9 0.2 1.3e-25 89.9 0.3 2.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59704.1 - 2.3e-08 34.2 0.0 4.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ANAPC_CDC26 PF10471.9 CCH59704.1 - 0.17 12.7 0.4 0.37 11.6 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 HTH_Tnp_Tc5 PF03221.16 CCH59705.1 - 0.0091 16.0 0.0 0.038 14.0 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Tap-RNA_bind PF09162.10 CCH59705.1 - 0.019 14.8 0.8 0.12 12.2 0.8 2.4 1 0 0 1 1 1 0 Tap, RNA-binding HTH_psq PF05225.16 CCH59705.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Pyr_redox_2 PF07992.14 CCH59706.1 - 4.1e-49 167.4 0.0 5.1e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCH59706.1 - 1.2e-11 45.0 0.0 1.1e-10 41.9 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCH59706.1 - 0.0011 18.3 0.0 1.8 7.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NPM1-C PF16276.5 CCH59706.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Nucleophosmin C-terminal domain Aldo_ket_red PF00248.21 CCH59707.1 - 2.5e-43 148.4 0.0 3.1e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Diphtheria_C PF02763.14 CCH59707.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain WD40 PF00400.32 CCH59708.1 - 4.5e-20 71.6 25.1 0.00055 20.7 0.3 10.4 10 1 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59708.1 - 1.9e-12 47.3 4.8 0.056 13.8 0.1 8.1 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH59708.1 - 5.7e-07 29.6 6.5 0.95 9.3 0.0 5.5 4 2 0 5 5 5 4 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 CCH59708.1 - 0.0013 18.1 0.0 0.0037 16.6 0.0 1.8 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5440 PF17509.2 CCH59708.1 - 0.11 12.0 0.1 8.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5440) WD40_like PF17005.5 CCH59708.1 - 0.13 11.6 7.0 0.8 9.0 0.5 4.0 4 1 0 4 4 4 0 WD40-like domain FlgD_ig PF13860.6 CCH59708.1 - 0.14 12.1 0.3 3.8 7.5 0.0 2.9 3 0 0 3 3 3 0 FlgD Ig-like domain Vma12 PF11712.8 CCH59710.1 - 1.4e-34 119.1 0.2 1.9e-34 118.7 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1461 PF07314.11 CCH59710.1 - 0.03 14.2 0.9 0.069 13.0 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1461) MMgT PF10270.9 CCH59710.1 - 0.065 13.6 0.2 0.23 11.9 0.0 1.9 1 1 1 2 2 2 0 Membrane magnesium transporter LapA_dom PF06305.11 CCH59710.1 - 0.26 11.1 2.0 0.22 11.4 0.2 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Prenyltransf PF01255.19 CCH59711.1 - 6.9e-62 208.9 0.4 9.2e-62 208.5 0.4 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Mito_carr PF00153.27 CCH59712.1 - 1.3e-47 159.7 8.7 1.2e-15 57.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 CCH59713.1 - 3.4e-14 53.0 16.2 0.0011 19.7 0.5 8.1 8 1 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59713.1 - 0.0052 17.1 0.4 21 5.5 0.0 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TF_Zn_Ribbon PF08271.12 CCH59713.1 - 0.066 12.7 1.3 0.18 11.4 1.3 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Lipoprotein_6 PF01441.19 CCH59713.1 - 3.1 7.8 13.4 0.039 14.0 5.0 2.2 3 0 0 3 3 3 0 Lipoprotein SRP9-21 PF05486.12 CCH59714.1 - 4e-22 78.4 5.4 4.5e-22 78.2 5.4 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) CGI-121 PF08617.10 CCH59714.1 - 0.018 15.2 2.0 0.023 14.8 2.0 1.1 1 0 0 1 1 1 0 Kinase binding protein CGI-121 SPRY PF00622.28 CCH59715.1 - 2.2e-13 50.4 0.3 2.4e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 SPRY domain PGM_PMM_I PF02878.16 CCH59716.1 - 1e-35 122.5 0.2 1.6e-35 121.8 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CCH59716.1 - 3.7e-27 94.8 0.0 6.7e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCH59716.1 - 5.2e-12 46.3 0.0 1.6e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CCH59716.1 - 1.6e-06 28.2 0.0 3.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.16 CCH59717.1 - 3e-30 105.4 6.8 3e-30 105.4 6.8 2.1 2 1 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CCH59717.1 - 5e-18 65.6 2.9 1e-17 64.7 0.4 2.3 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain His_Phos_1 PF00300.22 CCH59718.1 - 8.9e-10 38.6 0.1 1.7e-08 34.4 0.1 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Myosin_head PF00063.21 CCH59719.1 - 3.2e-230 765.9 9.5 4.2e-230 765.5 9.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CCH59719.1 - 1.4e-48 165.1 0.8 3.4e-48 163.8 0.8 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CCH59719.1 - 1.7e-12 46.7 0.1 3.5e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH59719.1 - 7.4e-08 32.1 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH59719.1 - 3.2e-06 26.7 0.0 6.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 CCH59719.1 - 0.03 14.7 0.0 0.094 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CCH59719.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 CCH59719.1 - 0.045 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CCH59719.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CCH59719.1 - 0.081 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Hpr_kinase_C PF07475.12 CCH59719.1 - 0.086 12.4 0.1 8.8 5.8 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 CCH59719.1 - 0.097 13.1 0.0 0.48 10.8 0.0 2.3 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CCH59719.1 - 0.26 11.8 1.2 1.2 9.7 0.0 2.8 2 0 0 2 2 2 0 ABC transporter She2p PF11435.8 CCH59720.1 - 3.6e-85 284.7 13.6 4.5e-85 284.4 13.6 1.1 1 0 0 1 1 1 1 RNA binding protein She2p CooT PF10133.9 CCH59720.1 - 0.035 14.4 0.1 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT GCR1_C PF12550.8 CCH59721.1 - 4.1e-19 68.7 0.5 4.1e-19 68.7 0.5 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Zein-binding PF04576.15 CCH59721.1 - 0.027 14.7 0.2 0.052 13.8 0.2 1.4 1 0 0 1 1 1 0 Zein-binding Med11 PF10280.9 CCH59722.1 - 1e-11 45.4 2.5 3.6e-11 43.7 0.4 1.9 2 0 0 2 2 2 1 Mediator complex protein SUKH-3 PF14433.6 CCH59722.1 - 0.0013 19.2 0.0 0.0016 18.9 0.0 1.1 1 0 0 1 1 1 1 SUKH-3 immunity protein ING PF12998.7 CCH59722.1 - 0.0028 18.2 1.6 1.2 9.8 0.6 2.1 1 1 1 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding DUF913 PF06025.12 CCH59722.1 - 0.013 14.5 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) APG17 PF04108.12 CCH59722.1 - 0.017 14.3 1.9 0.017 14.3 0.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg17 Mating_N PF12731.7 CCH59722.1 - 0.023 14.8 0.2 0.09 12.9 0.2 1.9 1 1 1 2 2 2 0 Mating-type protein beta 1 BLOC1_2 PF10046.9 CCH59722.1 - 0.036 14.4 1.1 0.33 11.3 0.1 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ArdA PF07275.11 CCH59722.1 - 0.042 14.4 0.1 0.067 13.8 0.0 1.3 1 1 0 1 1 1 0 Antirestriction protein (ArdA) YabA PF06156.13 CCH59722.1 - 0.042 14.5 3.1 2.3 8.9 1.5 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 CCH59722.1 - 0.057 13.5 0.6 0.12 12.4 0.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus RPW8 PF05659.11 CCH59722.1 - 0.061 13.0 0.9 1.3 8.7 0.0 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CdiI PF07262.11 CCH59722.1 - 0.077 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 CDI immunity protein CENP-H PF05837.12 CCH59722.1 - 0.089 13.2 2.4 0.19 12.1 0.1 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF2721 PF11026.8 CCH59722.1 - 0.17 11.8 0.1 0.94 9.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Spc7 PF08317.11 CCH59722.1 - 0.22 10.4 4.0 0.35 9.7 0.3 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein SRAP PF02586.14 CCH59723.1 - 1e-64 218.1 4.2 2e-64 217.2 4.2 1.5 1 1 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_2 PF07719.17 CCH59724.1 - 0.03 14.4 5.5 0.19 11.9 0.9 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCH59724.1 - 0.05 13.5 9.8 0.17 11.8 1.4 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59724.1 - 0.07 13.4 4.7 4.8 7.5 0.0 4.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59724.1 - 0.076 13.3 7.6 9.1 6.8 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 CCH59725.1 - 5.6e-46 153.6 11.6 3.5e-08 34.0 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59725.1 - 1.3e-10 41.5 0.8 0.067 13.5 0.0 5.4 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCH59725.1 - 3.8e-06 26.1 0.8 0.34 9.8 0.0 4.2 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCH59725.1 - 4.3e-06 25.7 1.8 0.11 11.1 0.1 4.5 3 2 0 4 4 4 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CCH59725.1 - 0.0004 20.3 0.1 0.0073 16.2 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 CCH59725.1 - 0.015 14.4 0.2 0.32 10.0 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) PD40 PF07676.12 CCH59725.1 - 0.058 13.4 0.1 22 5.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 CCH59725.1 - 0.12 11.1 0.9 4.3 6.0 0.4 3.6 2 1 1 3 3 3 0 Nup133 N terminal like Adaptin_N PF01602.20 CCH59726.1 - 1.4e-122 410.0 17.6 1.9e-122 409.5 17.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCH59726.1 - 7.9e-55 185.3 15.7 3.9e-52 176.6 6.7 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCH59726.1 - 2.4e-13 50.3 0.2 1.3e-05 25.4 0.0 5.6 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 CCH59726.1 - 2.3e-08 33.6 0.6 0.12 12.7 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat RTP1_C1 PF10363.9 CCH59726.1 - 0.0004 20.5 11.2 2 8.6 0.1 6.1 3 1 3 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CCH59726.1 - 0.0011 19.4 0.7 0.74 10.4 0.0 5.0 6 0 0 6 6 6 1 HEAT-like repeat Condensin2nSMC PF12422.8 CCH59726.1 - 0.041 14.0 0.1 0.93 9.7 0.1 3.0 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit CSTF2_hinge PF14327.6 CCH59726.1 - 0.29 11.6 4.6 2.4 8.7 0.0 4.0 5 0 0 5 5 5 0 Hinge domain of cleavage stimulation factor subunit 2 Cmc1 PF08583.10 CCH59727.1 - 4.1e-20 71.6 5.0 5e-20 71.3 5.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CCH59727.1 - 0.0039 16.9 1.9 0.005 16.5 1.9 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 CCH59727.1 - 0.039 14.3 4.1 2.2 8.7 0.2 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_1 PF00561.20 CCH59728.1 - 9.2e-31 107.4 1.7 4e-30 105.3 0.1 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CCH59728.1 - 1.5e-19 69.3 0.1 3e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CCH59728.1 - 6e-05 22.4 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CCH59728.1 - 0.01 15.6 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 CCH59728.1 - 0.016 14.9 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Snf7 PF03357.21 CCH59729.1 - 1.5e-47 161.4 19.3 1.5e-47 161.4 19.3 2.0 2 0 0 2 2 2 1 Snf7 Snapin_Pallidin PF14712.6 CCH59729.1 - 0.0074 16.7 7.4 0.0074 16.7 7.4 3.4 2 1 1 3 3 3 1 Snapin/Pallidin DASH_Dad4 PF08650.10 CCH59729.1 - 0.01 15.8 1.2 0.01 15.8 1.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 THP2 PF09432.10 CCH59729.1 - 0.013 15.6 3.5 0.013 15.6 3.5 2.1 2 0 0 2 2 2 0 Tho complex subunit THP2 Cob_adeno_trans PF01923.18 CCH59729.1 - 0.83 9.8 7.1 0.15 12.2 1.6 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF3573 PF12097.8 CCH59729.1 - 1.3 7.8 10.7 1.6 7.4 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Prefoldin_2 PF01920.20 CCH59729.1 - 2.6 8.0 18.2 0.63 10.0 1.9 3.5 3 1 0 3 3 3 0 Prefoldin subunit DUF16 PF01519.16 CCH59729.1 - 2.7 8.5 16.6 0.24 11.9 8.6 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF4140 PF13600.6 CCH59729.1 - 3.4 8.2 16.3 3.3 8.2 0.1 4.0 4 1 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) SNARE PF05739.19 CCH59730.1 - 9.2e-16 57.6 0.6 2.2e-15 56.4 0.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 CCH59730.1 - 4.6e-05 22.5 0.0 0.0001 21.4 0.0 1.7 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 CCH59730.1 - 0.00029 21.0 1.7 0.00029 21.0 1.7 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.25 CCH59730.1 - 0.0025 17.5 0.3 0.0025 17.5 0.3 2.8 2 1 1 3 3 3 1 Syntaxin DUF16 PF01519.16 CCH59730.1 - 0.02 15.4 0.6 0.02 15.4 0.6 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 MCPsignal PF00015.21 CCH59730.1 - 0.61 9.9 7.3 0.056 13.3 1.2 2.3 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0242 PF06785.11 CCH59730.1 - 7.6 6.6 14.9 0.73 9.9 6.7 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Osw5 PF17062.5 CCH59731.1 - 1.2e-27 95.8 14.2 1.4e-27 95.5 14.2 1.1 1 0 0 1 1 1 1 Outer spore wall 5 Peptidase_M50B PF13398.6 CCH59731.1 - 0.0044 16.7 0.9 0.0051 16.5 0.9 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Pox_Ag35 PF03286.14 CCH59732.1 - 6.1 6.6 22.4 6.4 6.5 8.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein T5orf172 PF10544.9 CCH59733.1 - 4e-10 40.2 0.3 3.8e-07 30.6 0.3 2.5 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CCH59733.1 - 1.1e-07 32.3 0.0 9.4e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Sigma_reg_C PF13791.6 CCH59733.1 - 0.18 12.0 0.9 0.28 11.4 0.9 1.4 1 1 0 1 1 1 0 Sigma factor regulator C-terminal WD40 PF00400.32 CCH59734.1 - 2.5e-25 88.2 0.4 1.1e-05 26.0 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59734.1 - 5.2e-08 33.1 0.0 0.014 15.7 0.0 4.9 2 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH59734.1 - 7.9e-05 22.6 1.1 0.33 10.8 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 CCH59734.1 - 0.01 14.8 0.1 0.32 9.9 0.1 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain 4F5 PF04419.14 CCH59735.1 - 2e-08 35.0 14.4 2e-08 35.0 14.4 2.1 2 0 0 2 2 2 1 4F5 protein family DEAD PF00270.29 CCH59736.1 - 3.6e-33 114.8 0.4 3.6e-33 114.8 0.4 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59736.1 - 3.8e-23 81.9 0.3 3.8e-23 81.9 0.3 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59736.1 - 6.7e-09 36.0 0.1 6.7e-09 36.0 0.1 2.6 2 1 2 4 4 4 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CCH59736.1 - 0.0057 16.0 0.2 0.0057 16.0 0.2 2.7 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit Pentapeptide_4 PF13599.6 CCH59736.1 - 0.023 14.8 0.1 0.11 12.6 0.1 2.1 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) AAA_22 PF13401.6 CCH59736.1 - 0.081 13.2 0.5 0.43 10.8 0.3 2.3 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 CCH59738.1 - 1.1e-53 182.2 0.0 1.4e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59738.1 - 1.1e-21 77.3 0.1 6.3e-21 74.8 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCH59738.1 - 0.0015 18.5 0.1 0.0024 17.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ldh_1_N PF00056.23 CCH59739.1 - 5.4e-44 149.7 0.1 9.5e-44 148.9 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CCH59739.1 - 1.7e-27 96.4 0.0 2.4e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CCH59739.1 - 1.8e-06 27.2 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCH59739.1 - 0.0018 18.7 0.0 0.0039 17.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CCH59739.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Arf PF00025.21 CCH59740.1 - 3.6e-41 140.5 0.3 4.3e-41 140.3 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCH59740.1 - 2.8e-16 59.8 0.0 3.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CCH59740.1 - 1.3e-13 50.9 1.1 7.3e-09 35.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CCH59740.1 - 2.7e-13 49.9 0.0 3.2e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CCH59740.1 - 6.4e-12 45.3 0.1 7.7e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH59740.1 - 5.5e-11 42.6 0.0 7.5e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CCH59740.1 - 1.5e-07 31.0 0.0 1.9e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CCH59740.1 - 1.1e-05 25.0 0.9 0.0081 15.7 0.4 2.1 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCH59740.1 - 2.3e-05 24.4 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 CCH59740.1 - 0.0008 18.8 0.1 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Septin FeoB_N PF02421.18 CCH59740.1 - 0.0012 18.4 0.8 0.017 14.7 0.8 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 CCH59740.1 - 0.0033 17.0 1.7 1.7 8.2 1.0 2.4 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CCH59740.1 - 0.0054 16.8 0.1 0.012 15.7 0.1 1.6 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.9 CCH59740.1 - 0.02 14.7 0.1 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CCH59740.1 - 0.021 14.5 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_lid_11 PF18198.1 CCH59740.1 - 0.025 14.4 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain CdhD PF03599.16 CCH59740.1 - 0.036 12.8 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit LprI PF07007.12 CCH59740.1 - 0.051 14.2 0.0 0.085 13.5 0.0 1.3 1 0 0 1 1 1 0 Lysozyme inhibitor LprI ABC_tran PF00005.27 CCH59740.1 - 0.055 14.0 0.1 0.08 13.4 0.1 1.4 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 CCH59740.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GATA PF00320.27 CCH59741.1 - 4e-15 55.1 1.8 1.2e-14 53.7 1.8 1.9 1 0 0 1 1 1 1 GATA zinc finger CAF1C_H4-bd PF12265.8 CCH59742.1 - 7.2e-16 58.2 0.1 3.8e-15 55.9 0.1 2.3 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCH59742.1 - 3.8e-10 40.2 3.3 0.0027 18.5 0.0 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59742.1 - 5.6e-07 29.8 1.9 0.032 14.5 0.2 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 CCH59742.1 - 4 7.1 28.3 1.3 8.7 4.9 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nramp PF01566.18 CCH59743.1 - 9e-94 314.4 14.7 1.2e-93 313.9 14.7 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4342 PF14242.6 CCH59743.1 - 0.19 11.8 0.7 0.9 9.6 0.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) DUF1430 PF07242.11 CCH59743.1 - 0.64 10.3 0.0 0.64 10.3 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1430) MARVEL PF01284.23 CCH59744.1 - 0.46 10.5 4.9 0.86 9.6 4.9 1.5 1 0 0 1 1 1 0 Membrane-associating domain DUF4282 PF14110.6 CCH59744.1 - 1 10.1 5.6 1.7 9.4 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Epiglycanin_TR PF05647.11 CCH59746.1 - 2.3 8.2 36.9 3.1e+02 1.4 36.6 2.6 1 1 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like Ribosomal_L15e PF00827.17 CCH59747.1 - 1.7e-89 298.7 10.8 2.1e-89 298.4 10.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.18 CCH59748.1 - 4.3e-92 308.7 0.0 8.7e-92 307.7 0.0 1.5 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCH59748.1 - 5.3e-26 90.6 0.1 6.4e-25 87.2 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain zf-C3HC4_3 PF13920.6 CCH59749.1 - 5e-08 32.7 16.6 8.1e-08 32.0 16.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH59749.1 - 0.021 14.7 11.3 0.038 13.8 11.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Aminotran_1_2 PF00155.21 CCH59750.1 - 9.5e-81 271.8 0.0 1.1e-80 271.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_2 PF07719.17 CCH59751.1 - 3e-09 36.3 8.1 0.0012 18.8 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCH59751.1 - 3.7e-08 32.9 6.2 0.00017 21.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59751.1 - 2e-05 24.4 15.3 0.0004 20.4 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59751.1 - 0.00034 20.8 0.6 0.057 13.7 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH59751.1 - 0.00035 20.4 1.6 7.1 6.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH59751.1 - 0.023 15.2 0.3 3.2 8.3 0.0 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCH59751.1 - 0.048 14.3 0.0 0.23 12.1 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCH59751.1 - 0.13 12.1 0.1 3 7.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.17 CCH59752.1 - 5e-103 345.5 32.8 5.9e-103 345.3 32.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PNTB_4TM PF12769.7 CCH59752.1 - 0.019 15.4 1.5 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Spc7 PF08317.11 CCH59752.1 - 0.23 10.3 0.0 0.46 9.3 0.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Mlh1_C PF16413.5 CCH59753.1 - 5.8e-84 281.7 0.4 9.6e-84 280.9 0.4 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CCH59753.1 - 6.4e-25 87.2 0.1 1.8e-24 85.7 0.1 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCH59753.1 - 2.8e-13 49.9 0.7 6.3e-13 48.7 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCH59753.1 - 5.9e-07 30.0 0.3 1.8e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PhoLip_ATPase_C PF16212.5 CCH59754.1 - 4.4e-70 236.3 22.5 4.4e-70 236.3 22.5 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCH59754.1 - 2.3e-21 75.2 1.5 2.3e-21 75.2 1.5 3.0 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCH59754.1 - 4.4e-12 45.9 0.0 2.1e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCH59754.1 - 5.8e-12 46.3 0.0 1.1e-05 25.8 0.0 3.5 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCH59754.1 - 4.2e-09 36.2 0.0 0.0011 18.5 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 CCH59754.1 - 0.0079 16.0 0.1 0.0079 16.0 0.1 3.9 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase NTS_2 PF15448.6 CCH59754.1 - 0.19 12.2 2.7 13 6.2 0.6 3.0 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein DnaJ PF00226.31 CCH59755.1 - 9.3e-24 83.3 1.2 2e-23 82.3 1.2 1.6 1 0 0 1 1 1 1 DnaJ domain TrmK PF04816.12 CCH59755.1 - 0.11 12.0 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase DUF3671 PF12420.8 CCH59755.1 - 0.11 12.6 0.6 5.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function Thi4 PF01946.17 CCH59756.1 - 1.5e-107 358.2 0.1 1.8e-107 357.9 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CCH59756.1 - 5e-06 26.3 1.0 1.2e-05 25.1 0.5 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCH59756.1 - 0.00015 21.0 0.4 0.00024 20.3 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CCH59756.1 - 0.00015 21.0 1.2 0.0017 17.5 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CCH59756.1 - 0.00017 21.7 0.3 0.00045 20.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCH59756.1 - 0.00039 19.7 0.2 0.0011 18.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCH59756.1 - 0.00041 20.4 0.1 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CCH59756.1 - 0.00059 19.3 0.1 0.00084 18.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCH59756.1 - 0.003 16.3 0.6 0.0049 15.6 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CCH59756.1 - 0.015 14.6 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCH59756.1 - 0.082 12.0 0.3 0.19 10.8 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CCH59756.1 - 0.22 10.3 0.3 0.29 9.9 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ArsA_ATPase PF02374.15 CCH59757.1 - 8.4e-116 386.4 0.0 9.8e-116 386.2 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CCH59757.1 - 4e-12 46.4 0.9 2.6e-10 40.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CCH59757.1 - 1.6e-08 34.7 0.0 3.5e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CCH59757.1 - 0.00098 18.6 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CCH59757.1 - 0.0011 18.4 1.3 0.0079 15.7 0.4 2.4 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CCH59757.1 - 0.022 14.4 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CCH59757.1 - 0.032 14.0 0.6 0.19 11.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain STI1 PF17830.1 CCH59757.1 - 0.034 14.1 0.3 11 6.1 0.0 2.6 2 0 0 2 2 2 0 STI1 domain AAA_25 PF13481.6 CCH59757.1 - 0.038 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CCH59757.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Neur_chan_memb PF02932.16 CCH59758.1 - 2.3 8.2 11.6 2.8 7.9 11.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLP_protease PF00574.23 CCH59758.1 - 5.3 6.9 7.9 0.54 10.1 1.6 2.1 2 1 0 2 2 2 0 Clp protease Striatin PF08232.12 CCH59759.1 - 0.00026 21.6 5.8 0.00032 21.3 5.8 1.2 1 0 0 1 1 1 1 Striatin family Lebercilin PF15619.6 CCH59759.1 - 0.0054 16.4 23.4 0.0071 16.0 23.4 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 CCH59759.1 - 0.063 12.7 22.8 0.081 12.4 22.8 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 CCH59759.1 - 0.082 11.8 18.0 0.1 11.4 18.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CCH59759.1 - 0.21 9.5 12.1 0.25 9.2 12.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 CCH59759.1 - 0.22 11.4 15.9 0.14 12.0 14.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FAM76 PF16046.5 CCH59759.1 - 0.29 10.4 21.2 1.4 8.3 21.2 1.7 1 1 0 1 1 1 0 FAM76 protein GPAT_N PF14829.6 CCH59759.1 - 0.35 10.9 2.9 0.55 10.3 0.6 2.3 1 1 1 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal eIF-4B PF06273.11 CCH59759.1 - 0.55 9.2 3.6 0.66 9.0 3.6 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Orbi_VP5 PF00901.17 CCH59759.1 - 0.64 8.3 3.7 0.76 8.1 3.7 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Atg14 PF10186.9 CCH59759.1 - 0.84 8.7 12.2 1.2 8.2 12.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 CCH59759.1 - 0.96 9.5 28.6 3.1 7.8 18.7 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Exonuc_VII_L PF02601.15 CCH59759.1 - 1 8.9 9.2 1.3 8.5 9.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 CCH59759.1 - 1.7 8.7 14.1 8.5 6.5 14.1 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Jnk-SapK_ap_N PF09744.9 CCH59759.1 - 2.8 8.2 22.9 2.5 8.3 9.3 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 CCH59759.1 - 3.4 8.4 21.4 2.1 9.0 13.2 2.9 1 1 1 2 2 2 0 SlyX DUF848 PF05852.11 CCH59759.1 - 3.6 7.7 15.8 8.9 6.4 7.8 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FemAB PF02388.16 CCH59759.1 - 5.2 5.8 11.6 8.5 5.1 11.6 1.3 1 0 0 1 1 1 0 FemAB family DUF3450 PF11932.8 CCH59759.1 - 5.4 6.2 22.2 4.8 6.4 18.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ALMT PF11744.8 CCH59759.1 - 6.4 5.5 7.3 7.4 5.3 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Vps51 PF08700.11 CCH59759.1 - 6.5 6.9 16.6 6 7.0 5.9 2.4 1 1 1 2 2 2 0 Vps51/Vps67 ApoO PF09769.9 CCH59759.1 - 7.3 6.6 6.1 7.9 6.5 0.9 2.3 2 0 0 2 2 2 0 Apolipoprotein O TMPIT PF07851.13 CCH59759.1 - 9.2 5.4 13.5 14 4.8 13.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_S8 PF00410.19 CCH59760.1 - 1.9e-11 44.0 0.0 1.9e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 zf-met PF12874.7 CCH59761.1 - 1.1e-06 28.8 2.6 2.1e-06 27.9 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCH59761.1 - 0.0091 16.3 2.9 0.022 15.0 2.9 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 CCH59761.1 - 0.023 14.8 0.3 0.023 14.8 0.3 2.0 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_4 PF13894.6 CCH59761.1 - 0.086 13.7 1.2 0.22 12.5 1.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH59761.1 - 0.71 10.5 3.1 1.5 9.4 3.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PNK3P PF08645.11 CCH59762.1 - 9.2e-42 142.5 1.8 1.2e-41 142.1 1.8 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF3024 PF11225.8 CCH59762.1 - 0.0017 18.6 1.4 0.0041 17.3 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3024) PAP_assoc PF03828.19 CCH59762.1 - 0.25 11.6 1.7 0.39 10.9 0.0 2.2 2 1 0 2 2 2 0 Cid1 family poly A polymerase RPN6_N PF18055.1 CCH59763.1 - 1.3e-36 125.5 1.8 1.3e-36 125.5 1.8 2.7 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CCH59763.1 - 1.2e-17 64.3 2.3 2.2e-17 63.4 0.5 2.4 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CCH59763.1 - 1.8e-13 50.0 1.2 4.9e-13 48.6 1.2 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 CCH59763.1 - 5.2e-06 26.7 0.8 0.023 15.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCH59763.1 - 0.013 14.8 1.5 0.028 13.6 0.2 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCH59763.1 - 0.016 15.8 0.1 1.4 9.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH59763.1 - 0.017 15.1 0.0 3.5 7.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCH59763.1 - 0.021 14.9 0.6 16 5.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat SH3_14 PF18343.1 CCH59763.1 - 0.048 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Dda helicase SH3 domain TPR_MalT PF17874.1 CCH59763.1 - 0.058 12.7 0.7 1.5 8.1 0.2 2.3 1 1 1 2 2 2 0 MalT-like TPR region PMT PF02366.18 CCH59764.1 - 1.4e-74 250.8 18.4 1.4e-74 250.8 18.4 2.1 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCH59764.1 - 1.8e-57 194.2 19.5 1.8e-57 194.2 19.5 2.0 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCH59764.1 - 1.7e-40 138.8 0.0 1.7e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 MIR domain Borrelia_P83 PF05262.11 CCH59764.1 - 0.0042 15.6 6.2 0.0061 15.1 6.2 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein AAA_32 PF13654.6 CCH59764.1 - 0.021 13.6 9.3 0.031 13.1 9.3 1.1 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 CCH59764.1 - 0.6 10.0 19.4 0.95 9.4 19.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 CCH59764.1 - 1.5 8.3 7.5 2.4 7.6 7.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CDC45 PF02724.14 CCH59764.1 - 1.6 7.0 5.9 2.3 6.4 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein UBX PF00789.20 CCH59765.1 - 8.3e-15 54.8 0.0 1.8e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 UBX domain LAM_C PF12544.8 CCH59765.1 - 0.26 11.5 1.1 0.44 10.7 1.1 1.3 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Prenyltrans PF00432.21 CCH59766.1 - 5.2e-29 99.7 12.5 1.9e-09 37.1 0.2 5.1 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Peptidase_C2 PF00648.21 CCH59767.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Calpain family cysteine protease Nup84_Nup100 PF04121.13 CCH59768.1 - 1.2e-186 622.0 22.1 1.4e-186 621.8 22.1 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup96 PF12110.8 CCH59768.1 - 0.045 12.9 0.2 0.2 10.7 0.0 2.1 3 0 0 3 3 3 0 Nuclear protein 96 Ribosomal_L6 PF00347.23 CCH59769.1 - 2.2e-28 98.8 11.9 1.9e-14 54.1 3.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Iwr1 PF08574.10 CCH59770.1 - 2.3e-15 57.4 9.9 2.3e-15 57.4 9.9 4.7 4 2 0 4 4 4 1 Transcription factor Iwr1 adh_short PF00106.25 CCH59771.1 - 1.8e-35 122.2 0.0 4.4e-35 120.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH59771.1 - 1.5e-22 80.3 0.0 3.2e-22 79.2 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH59771.1 - 9.6e-07 28.9 0.0 3.1e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CCH59771.1 - 0.053 12.5 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sigma54_activ_2 PF14532.6 CCH59771.1 - 0.099 12.8 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNase_PH PF01138.21 CCH59772.1 - 5.1e-09 36.7 0.3 8.6e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCH59772.1 - 0.002 18.1 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TBCA PF02970.16 CCH59773.1 - 0.018 15.3 2.7 0.39 11.1 0.7 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor A K-box PF01486.17 CCH59773.1 - 0.034 14.3 2.6 0.053 13.7 2.6 1.4 1 0 0 1 1 1 0 K-box region APG17 PF04108.12 CCH59773.1 - 0.037 13.1 4.0 0.12 11.5 4.0 1.7 1 1 0 1 1 1 0 Autophagy protein Apg17 RPA_interact_M PF14767.6 CCH59773.1 - 0.11 13.1 5.6 0.2 12.2 5.6 1.5 1 1 0 1 1 1 0 Replication protein A interacting middle DUF676 PF05057.14 CCH59774.1 - 2.2e-58 197.4 0.0 3.9e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 CCH59774.1 - 0.0031 17.3 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CCH59774.1 - 0.029 13.6 0.0 0.071 12.3 0.0 1.6 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CCH59774.1 - 0.065 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 CCH59774.1 - 0.085 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PCRF PF03462.18 CCH59775.1 - 1.8e-48 165.0 3.2 6.4e-47 159.9 0.0 2.2 2 0 0 2 2 2 2 PCRF domain RF-1 PF00472.20 CCH59775.1 - 3.3e-34 117.3 6.1 5.9e-34 116.5 6.1 1.4 1 0 0 1 1 1 1 RF-1 domain SecA_SW PF07516.13 CCH59775.1 - 0.02 14.9 1.0 0.02 14.9 1.0 1.9 2 1 0 2 2 2 0 SecA Wing and Scaffold domain MLD PF11647.8 CCH59775.1 - 0.078 13.3 0.7 0.58 10.5 0.2 2.6 2 0 0 2 2 2 0 Membrane Localization Domain GCD14 PF08704.10 CCH59775.1 - 0.081 12.6 1.0 0.19 11.4 0.2 2.0 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF1912 PF08930.10 CCH59775.1 - 0.11 12.7 0.8 36 4.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) DUF4635 PF15466.6 CCH59775.1 - 5.6 6.5 6.7 0.73 9.4 0.5 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4635) Pkinase PF00069.25 CCH59776.1 - 8.2e-73 245.0 0.0 9.2e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59776.1 - 2.7e-32 112.1 0.0 3.5e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCH59776.1 - 0.00022 21.2 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCH59776.1 - 0.0014 18.0 0.0 0.003 16.9 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CCH59776.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CCH59776.1 - 0.042 12.8 0.0 0.062 12.2 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DUF2418 PF10332.9 CCH59777.1 - 2.6e-16 59.9 2.0 2.6e-16 59.9 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ADH_zinc_N_2 PF13602.6 CCH59778.1 - 3.4e-09 37.9 0.0 7.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH59778.1 - 6.2e-05 22.8 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH59778.1 - 0.0037 17.2 0.0 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 CCH59778.1 - 0.026 14.3 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) SH3_2 PF07653.17 CCH59779.1 - 1.8e-06 27.5 0.1 3.4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCH59779.1 - 7.3e-06 25.5 0.5 1.7e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCH59779.1 - 8.6e-05 22.3 0.1 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.19 CCH59779.1 - 0.0011 19.4 0.0 0.0047 17.4 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily Med5 PF08689.10 CCH59780.1 - 0 1188.3 121.3 0 1144.6 107.7 2.0 1 1 1 2 2 2 2 Mediator complex subunit Med5 Dapper PF15268.6 CCH59780.1 - 0.33 9.8 12.0 0.61 8.9 12.0 1.4 1 0 0 1 1 1 0 Dapper zf-Tim10_DDP PF02953.15 CCH59781.1 - 3.1e-19 68.4 2.8 4.2e-19 68.0 2.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger eIF-5_eIF-2B PF01873.17 CCH59782.1 - 0.084 12.8 0.6 0.16 11.8 0.6 1.5 1 0 0 1 1 1 0 Domain found in IF2B/IF5 AMPK1_CBM PF16561.5 CCH59783.1 - 2.3e-09 37.4 0.1 9.8e-09 35.3 0.1 2.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Chitin_synth_2 PF03142.15 CCH59784.1 - 0.082 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Chitin synthase Gly-zipper_Omp PF13488.6 CCH59784.1 - 0.17 11.9 4.3 0.33 11.0 4.3 1.4 1 0 0 1 1 1 0 Glycine zipper Ribosomal_L22 PF00237.19 CCH59785.1 - 2.9e-21 75.6 0.1 7.9e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.11 CCH59786.1 - 5.3e-68 227.7 1.3 7.1e-68 227.3 1.3 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Phage_Gp23 PF10669.9 CCH59786.1 - 0.076 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) CitMHS PF03600.16 CCH59786.1 - 0.2 10.8 1.8 0.29 10.3 1.8 1.3 1 1 0 1 1 1 0 Citrate transporter Ribosomal_S3_C PF00189.20 CCH59787.1 - 3.2e-23 82.1 0.9 2.1e-22 79.4 0.5 2.4 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CCH59787.1 - 4.7e-12 45.6 0.2 2.5e-11 43.3 0.3 2.1 2 0 0 2 2 2 1 KH domain adh_short PF00106.25 CCH59788.1 - 3.3e-07 30.0 0.0 4.2e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH59788.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 CCH59789.1 - 1.2e-06 29.1 3.5 0.042 14.7 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59789.1 - 0.00011 22.5 0.1 0.014 15.6 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CCH59790.1 - 6.4e-48 163.4 0.0 1.4e-47 162.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59790.1 - 4.5e-21 75.3 0.0 7.5e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59790.1 - 0.15 11.4 0.2 0.59 9.4 0.0 2.0 2 1 1 3 3 3 0 Kinase-like APH PF01636.23 CCH59790.1 - 0.27 11.1 0.1 0.45 10.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCH59790.1 - 2.1 7.9 5.4 2.1 7.9 0.1 2.8 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L11 PF00298.19 CCH59791.1 - 1.7e-25 89.3 1.0 1.9e-25 89.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CCH59791.1 - 5.8e-25 86.9 0.2 8.5e-25 86.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain UCH PF00443.29 CCH59792.1 - 1.8e-49 168.6 3.3 1.8e-49 168.6 3.3 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH59792.1 - 6.4e-15 55.6 7.0 6.4e-15 55.6 7.0 5.2 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-BED PF02892.15 CCH59792.1 - 0.096 12.7 1.0 6.6 6.8 0.2 2.8 2 0 0 2 2 2 0 BED zinc finger Prenyltrans PF00432.21 CCH59792.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Tim17 PF02466.19 CCH59793.1 - 2.9e-39 133.9 3.5 3.6e-39 133.6 3.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Arm PF00514.23 CCH59795.1 - 8.4e-27 92.3 13.5 2e-07 30.8 0.1 8.7 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCH59795.1 - 4.7e-07 30.2 4.8 1.3e-06 28.7 4.8 1.8 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 CCH59795.1 - 0.00032 21.1 0.0 0.079 13.5 0.0 4.2 3 1 2 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 CCH59795.1 - 0.013 15.9 0.0 9.3 6.7 0.0 3.3 1 1 1 3 3 3 0 HEAT repeats HEAT PF02985.22 CCH59795.1 - 0.065 13.5 0.4 3.7 8.1 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat RICTOR_V PF14668.6 CCH59795.1 - 0.34 11.2 6.3 3.5 8.0 0.1 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 MtrF PF09472.10 CCH59796.1 - 0.0049 16.2 0.0 0.0094 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) OCRE PF17780.1 CCH59796.1 - 0.096 12.7 15.2 29 4.8 0.1 5.7 1 1 5 6 6 6 0 OCRE domain Cdc13_OB2 PF18691.1 CCH59797.1 - 4.9e-21 74.9 3.9 4.9e-21 74.9 3.9 3.7 3 0 0 3 3 3 1 Cell division control protein 13, OB2 domain CDC13_N PF16853.5 CCH59797.1 - 1.3e-16 60.7 13.6 1.3e-16 60.7 13.6 5.0 4 2 0 4 4 4 1 Cell division control protein 13 N-terminus Plug PF07715.15 CCH59797.1 - 8.1 7.1 9.0 8.2 7.0 1.5 3.3 4 0 0 4 4 4 0 TonB-dependent Receptor Plug Domain RRM_1 PF00076.22 CCH59799.1 - 7.1e-14 51.4 0.1 6.6e-06 25.9 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.18 CCH59800.1 - 2.2e-67 227.3 11.7 7.9e-67 225.5 6.4 2.9 2 1 0 2 2 2 1 Septin AAA_28 PF13521.6 CCH59800.1 - 0.0037 17.5 0.9 0.014 15.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 CCH59800.1 - 0.022 14.8 0.0 0.022 14.8 0.0 2.9 3 1 0 3 3 3 0 Dynamin family MMR_HSR1 PF01926.23 CCH59800.1 - 0.043 13.9 5.0 0.12 12.4 0.9 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CCH59800.1 - 0.06 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CCH59800.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PEMT PF04191.13 CCH59801.1 - 8.3e-54 180.5 8.4 9.2e-29 100.0 0.5 3.3 3 0 0 3 3 3 2 Phospholipid methyltransferase Arrestin_N PF00339.29 CCH59802.1 - 4.9e-18 65.6 0.4 1.7e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CCH59802.1 - 8.6e-09 36.0 1.4 8.6e-09 36.0 1.4 2.9 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain A2M PF00207.22 CCH59802.1 - 0.011 15.6 0.3 0.55 10.1 0.1 2.5 2 0 0 2 2 2 0 Alpha-2-macroglobulin family Sec20 PF03908.13 CCH59803.1 - 1.9 8.5 6.7 3.5 7.6 3.6 3.2 2 0 0 2 2 2 0 Sec20 DUF2046 PF09755.9 CCH59804.1 - 0.0045 16.3 0.2 0.0071 15.6 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) SAM_2 PF07647.17 CCH59804.1 - 0.054 13.6 0.5 0.14 12.3 0.5 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) YMF19 PF02326.15 CCH59804.1 - 3.3 8.6 7.0 1.2 10.0 0.1 3.0 3 1 1 4 4 4 0 Plant ATP synthase F0 Glyco_tran_28_C PF04101.16 CCH59805.1 - 1.4e-15 57.6 0.3 3e-14 53.3 0.3 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain AAA PF00004.29 CCH59806.1 - 3.1e-43 147.4 0.0 6.1e-43 146.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH59806.1 - 1.1e-14 53.9 0.1 3e-14 52.5 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCH59806.1 - 6.3e-07 29.2 0.2 1.5e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCH59806.1 - 8e-07 29.3 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCH59806.1 - 1.9e-06 27.9 0.0 1.2e-05 25.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCH59806.1 - 1.3e-05 25.7 0.1 0.00031 21.2 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CCH59806.1 - 3e-05 24.3 0.2 0.0059 16.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CCH59806.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCH59806.1 - 0.00097 19.7 1.0 0.022 15.3 0.0 3.0 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CCH59806.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CCH59806.1 - 0.0022 18.1 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2072 PF09845.9 CCH59806.1 - 0.0033 17.7 0.5 0.0069 16.6 0.5 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein AAA_28 PF13521.6 CCH59806.1 - 0.0042 17.4 0.0 0.0086 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCH59806.1 - 0.0067 16.3 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CCH59806.1 - 0.0099 15.3 0.2 0.028 13.8 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CCH59806.1 - 0.012 14.9 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CCH59806.1 - 0.014 15.5 0.0 0.036 14.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 CCH59806.1 - 0.018 14.5 0.0 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 CCH59806.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CEP63 PF17045.5 CCH59806.1 - 0.025 14.5 0.3 0.048 13.6 0.3 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa AAA_24 PF13479.6 CCH59806.1 - 0.026 14.3 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCH59806.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Tropomyosin PF00261.20 CCH59806.1 - 0.034 13.5 2.7 0.063 12.6 0.6 2.0 2 0 0 2 2 2 0 Tropomyosin RNA_helicase PF00910.22 CCH59806.1 - 0.035 14.5 0.0 0.091 13.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CCH59806.1 - 0.04 14.2 0.1 0.64 10.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCH59806.1 - 0.052 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3372 PF11852.8 CCH59806.1 - 0.061 12.8 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) DUF815 PF05673.13 CCH59806.1 - 0.068 12.3 0.2 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CCH59806.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CCH59806.1 - 0.088 12.1 0.0 0.24 10.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin APG6_N PF17675.1 CCH59806.1 - 0.1 13.1 0.3 0.21 12.1 0.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Parvo_NS1 PF01057.17 CCH59806.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CCH59806.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCH59806.1 - 0.16 11.9 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain MIF4G PF02854.19 CCH59807.1 - 7.1e-48 163.1 0.3 1.6e-47 161.9 0.3 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CCH59807.1 - 1.6e-23 82.6 0.4 4.8e-23 81.1 0.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Cas_Csa4 PF09703.10 CCH59807.1 - 0.068 12.5 0.1 0.068 12.5 0.1 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa4) TYW3 PF02676.14 CCH59808.1 - 4.4e-65 219.0 0.0 5.7e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Gtr1_RagA PF04670.12 CCH59809.1 - 2.2e-67 226.8 0.8 3e-67 226.4 0.8 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CCH59809.1 - 0.0016 17.9 0.0 0.0043 16.5 0.0 1.8 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3804 PF12707.7 CCH59809.1 - 0.015 15.0 0.7 0.049 13.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) AAA_14 PF13173.6 CCH59809.1 - 0.026 14.5 0.0 0.079 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCH59809.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AsnC_trans_reg PF01037.21 CCH59809.1 - 0.081 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Zeta_toxin PF06414.12 CCH59810.1 - 0.0043 16.4 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.22 CCH59810.1 - 0.014 15.7 0.2 0.077 13.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 CCH59810.1 - 0.024 15.2 0.1 0.077 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCH59810.1 - 0.045 14.1 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Curto_V3 PF07436.11 CCH59810.1 - 0.069 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Curtovirus V3 protein AAA_14 PF13173.6 CCH59810.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCH59810.1 - 0.11 12.2 0.0 0.95 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCH59810.1 - 0.17 11.6 0.3 0.98 9.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain tRNA_bind PF01588.20 CCH59811.1 - 1.3e-17 63.7 0.7 2.1e-17 63.0 0.7 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Aconitase PF00330.20 CCH59812.1 - 6.1e-149 496.9 0.0 7.7e-149 496.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCH59812.1 - 4.3e-47 159.7 0.1 8.6e-47 158.7 0.1 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.27 CCH59813.1 - 1.7e-42 146.0 0.0 4e-40 138.2 0.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CCH59813.1 - 9.5e-29 100.1 0.1 3.5e-28 98.2 0.1 2.0 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Caleosin PF05042.13 CCH59813.1 - 0.028 14.4 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Caleosin related protein Polysacc_deac_1 PF01522.21 CCH59814.1 - 1.4e-24 86.4 0.0 2.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GRIP PF01465.20 CCH59815.1 - 4.2e-13 49.0 0.1 1.3e-12 47.4 0.1 1.9 1 0 0 1 1 1 1 GRIP domain ATG16 PF08614.11 CCH59815.1 - 2.5e-06 27.9 164.7 0.0042 17.3 26.3 9.4 1 1 8 10 10 10 4 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CCH59815.1 - 9.2e-05 22.5 20.1 9.2e-05 22.5 20.1 9.8 2 2 7 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 CCH59815.1 - 0.0056 16.1 10.3 0.0056 16.1 10.3 10.4 1 1 10 11 11 11 2 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 CCH59815.1 - 0.0086 16.3 19.2 0.0086 16.3 19.2 10.5 1 1 9 11 11 11 5 Fibrinogen alpha/beta chain family DHR10 PF18595.1 CCH59815.1 - 0.0089 16.1 16.7 0.0089 16.1 16.7 11.4 1 1 9 12 12 12 1 Designed helical repeat protein 10 domain T7SS_ESX_EspC PF10824.8 CCH59815.1 - 0.2 12.2 4.6 11 6.6 0.1 4.4 4 1 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm Abi_C PF14355.6 CCH59815.1 - 0.26 11.4 2.2 1.4 9.1 0.3 3.4 2 0 0 2 2 2 0 Abortive infection C-terminus RasGEF PF00617.19 CCH59816.1 - 5.4e-54 183.1 0.5 5.3e-53 179.8 0.2 3.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CCH59816.1 - 1.6e-21 76.5 0.7 1.6e-21 76.5 0.7 5.3 3 1 1 4 4 4 1 RasGEF N-terminal motif SH3_2 PF07653.17 CCH59816.1 - 7.8e-05 22.3 0.3 0.00031 20.3 0.3 2.0 1 1 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCH59816.1 - 8.2e-05 22.4 0.1 0.00039 20.2 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CCH59816.1 - 0.00021 20.9 4.0 0.00025 20.6 0.2 3.0 4 0 0 4 4 4 1 SH3 domain tRNA-synt_2 PF00152.20 CCH59817.1 - 1.4e-80 270.8 1.0 2.6e-80 269.9 1.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCH59817.1 - 2.8e-08 33.6 1.7 3.3e-08 33.4 0.4 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCH59817.1 - 0.082 12.4 1.5 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) FAM178 PF14816.6 CCH59817.1 - 0.24 10.3 5.9 0.39 9.7 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 Cytadhesin_P30 PF07271.11 CCH59817.1 - 0.44 10.1 1.5 0.84 9.1 1.5 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUP PF00674.18 CCH59818.1 - 0.027 14.6 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 DUP family Got1 PF04178.12 CCH59818.1 - 0.095 13.1 0.9 0.14 12.6 0.9 1.2 1 0 0 1 1 1 0 Got1/Sft2-like family HMMR_C PF15908.5 CCH59818.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Pet191_N PF10203.9 CCH59819.1 - 0.056 13.8 1.3 0.12 12.7 1.3 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CCH59819.1 - 0.09 12.9 0.2 0.18 12.0 0.2 1.5 1 1 0 1 1 1 0 CHCH domain COX17 PF05051.13 CCH59819.1 - 0.19 12.1 2.4 4.4 7.7 0.2 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 CCH59820.1 - 2e-41 142.1 0.0 2.2e-40 138.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59820.1 - 4.1e-19 68.9 0.0 1e-18 67.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH59820.1 - 0.0043 15.9 0.0 0.0067 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCH59820.1 - 0.023 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCH59820.1 - 0.071 12.4 0.4 0.92 8.8 0.0 2.7 4 0 0 4 4 4 0 Kinase-like DUF1611 PF07755.11 CCH59820.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain Ig_4 PF16680.5 CCH59820.1 - 0.45 10.8 1.7 1 9.7 0.1 2.5 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 delta chain Ribonucleas_3_3 PF14622.6 CCH59821.1 - 4.3e-21 75.4 0.1 6.7e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CCH59821.1 - 1.2e-06 29.1 0.1 4.5e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease III domain GIT_SHD PF08518.11 CCH59822.1 - 6.9e-23 80.0 5.1 1.4e-10 40.6 0.2 3.5 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 CCH59822.1 - 3.7e-05 23.8 1.7 3.7e-05 23.8 1.7 4.5 4 1 0 4 4 4 1 G protein-coupled receptor kinase-interacting protein 1 C term TPP_enzyme_N PF02776.18 CCH59823.1 - 2.1e-31 108.8 0.1 3.5e-31 108.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH59823.1 - 6.1e-28 97.3 0.0 5.4e-27 94.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH59823.1 - 1.2e-12 47.9 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC_membrane PF00664.23 CCH59824.1 - 2.9e-96 322.3 49.0 2.7e-57 194.5 18.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCH59824.1 - 7.7e-61 204.6 0.0 1.4e-29 103.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCH59824.1 - 6.2e-16 58.5 0.0 7.5e-06 25.5 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCH59824.1 - 3.8e-09 36.9 1.4 0.0037 17.5 0.0 4.2 3 2 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 CCH59824.1 - 1.3e-07 31.7 0.0 0.00094 19.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CCH59824.1 - 8.4e-07 28.6 0.2 0.0075 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 CCH59824.1 - 1.1e-05 25.6 0.0 0.034 14.3 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCH59824.1 - 1.2e-05 25.8 0.0 0.35 11.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CCH59824.1 - 1.3e-05 24.2 6.9 0.00018 20.4 0.2 3.3 4 0 0 4 4 4 1 Predicted ATPase of the ABC class RNA_helicase PF00910.22 CCH59824.1 - 8.9e-05 22.8 0.0 0.19 12.2 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CCH59824.1 - 0.00016 22.2 0.0 0.39 11.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 CCH59824.1 - 0.00018 22.0 7.8 0.37 11.2 0.1 3.8 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 CCH59824.1 - 0.00025 20.8 0.1 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCH59824.1 - 0.00058 19.9 0.9 0.61 10.2 0.6 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CCH59824.1 - 0.00091 19.1 21.6 4.1 7.1 0.1 5.4 3 2 2 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 CCH59824.1 - 0.00092 18.9 0.0 0.068 12.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 CCH59824.1 - 0.00096 18.5 0.0 0.45 9.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 CCH59824.1 - 0.0015 18.5 3.4 0.51 10.2 1.0 3.4 2 1 0 2 2 2 1 NACHT domain Trp_repressor PF01371.19 CCH59824.1 - 0.0016 18.5 0.6 0.12 12.6 0.0 3.2 3 0 0 3 3 2 1 Trp repressor protein Sigma54_activat PF00158.26 CCH59824.1 - 0.0019 17.9 0.0 0.074 12.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_5 PF07728.14 CCH59824.1 - 0.0025 17.8 0.1 4.2 7.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CCH59824.1 - 0.0037 17.7 0.1 0.95 9.9 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CCH59824.1 - 0.0038 16.3 0.1 0.25 10.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein PRK PF00485.18 CCH59824.1 - 0.0043 16.8 0.0 0.48 10.1 0.0 2.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 CCH59824.1 - 0.0043 16.6 0.2 0.38 10.2 0.1 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 CCH59824.1 - 0.0053 17.0 0.9 3.5 7.8 0.0 3.9 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 CCH59824.1 - 0.0055 16.6 0.2 0.53 10.2 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 CCH59824.1 - 0.0082 15.4 0.1 2.4 7.3 0.1 2.6 2 0 0 2 2 2 1 Septin AAA_30 PF13604.6 CCH59824.1 - 0.0093 15.7 0.0 3.1 7.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 CCH59824.1 - 0.0098 15.8 0.6 0.43 10.5 0.0 3.3 3 0 0 3 3 2 1 Rad17 P-loop domain NB-ARC PF00931.22 CCH59824.1 - 0.011 14.9 0.2 5.8 6.0 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain Sigma54_activ_2 PF14532.6 CCH59824.1 - 0.023 14.8 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Terminase_6 PF03237.15 CCH59824.1 - 0.03 14.0 0.1 0.1 12.3 0.2 1.8 2 0 0 2 2 1 0 Terminase-like family AAA_25 PF13481.6 CCH59824.1 - 0.033 13.8 0.1 3.1 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CCH59824.1 - 0.05 13.6 11.0 0.2 11.7 0.0 4.8 5 0 0 5 5 4 0 AAA domain FtsK_SpoIIIE PF01580.18 CCH59824.1 - 0.056 12.8 0.0 4.2 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 CCH59824.1 - 0.058 13.8 0.0 9 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CCH59824.1 - 0.07 12.7 0.4 6.6 6.3 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF3584 PF12128.8 CCH59824.1 - 0.078 10.5 0.1 0.33 8.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) SbcCD_C PF13558.6 CCH59824.1 - 0.099 12.9 0.6 4.1 7.7 0.1 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 CCH59824.1 - 0.14 11.4 1.3 16 4.7 0.1 3.0 3 0 0 3 3 3 0 KaiC CbiA PF01656.23 CCH59824.1 - 0.15 12.1 0.6 13 5.9 0.1 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 CCH59824.1 - 1.7 8.7 10.1 4.2 7.4 0.4 3.9 4 0 0 4 4 3 0 Helicase HerA, central domain Mog1 PF04603.12 CCH59825.1 - 2.1e-39 135.0 0.1 2.8e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.15 CCH59826.1 - 4.4e-13 49.7 0.0 4.9e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Vir_act_alpha_C PF10400.9 CCH59826.1 - 0.091 13.5 0.1 1.8 9.3 0.2 2.5 2 0 0 2 2 2 0 Virulence activator alpha C-term Radial_spoke PF04712.12 CCH59826.1 - 0.096 11.6 4.3 0.43 9.5 0.0 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein Septin PF00735.18 CCH59827.1 - 1.6e-108 362.3 0.0 2.6e-108 361.6 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCH59827.1 - 6.7e-08 32.6 0.0 1.7e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCH59827.1 - 1.8e-06 28.1 7.2 0.00032 20.8 0.6 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 CCH59827.1 - 4.8e-06 26.0 0.1 4.8e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 CCH59827.1 - 0.00022 21.1 9.2 0.00027 20.9 1.6 3.4 3 1 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 CCH59827.1 - 0.00037 21.0 0.5 0.0015 19.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 CCH59827.1 - 0.0007 19.2 0.7 0.26 10.8 0.2 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IIGP PF05049.13 CCH59827.1 - 0.0052 15.9 0.1 0.0098 15.0 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 CCH59827.1 - 0.0065 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 CCH59827.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 CCH59827.1 - 0.031 13.4 3.0 0.074 12.2 0.1 2.4 2 1 0 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.6 CCH59827.1 - 0.04 14.2 0.3 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCH59827.1 - 0.069 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 CCH59827.1 - 0.074 12.8 1.4 4.5 7.0 0.1 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 CCH59827.1 - 0.098 12.7 1.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 CCH59827.1 - 0.1 12.2 0.8 0.51 9.9 0.2 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Aldo_ket_red PF00248.21 CCH59828.1 - 3.4e-67 226.7 0.1 4e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BATS PF06968.13 CCH59829.1 - 1.8e-21 76.1 0.0 5e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CCH59829.1 - 9.4e-18 65.1 0.2 3.8e-17 63.2 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 CCH59829.1 - 0.0022 17.7 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Mito_carr PF00153.27 CCH59830.1 - 3.6e-64 212.7 0.5 1.7e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DHO_dh PF01180.21 CCH59831.1 - 2.5e-93 312.5 0.0 2.9e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CCH59831.1 - 8.3e-09 34.9 0.0 0.00017 20.8 0.0 2.1 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.21 CCH59831.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase Sugar_tr PF00083.24 CCH59832.1 - 5.6e-158 526.5 32.8 6.5e-158 526.3 32.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59832.1 - 1.4e-33 116.3 31.5 5.2e-29 101.3 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 CCH59832.1 - 0.21 11.1 3.1 1.4 8.4 1.0 3.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Flocculin PF00624.18 CCH59833.1 - 5e-55 183.5 182.7 1.4e-11 44.5 17.1 18.8 14 2 4 18 18 18 10 Flocculin repeat DUF1214 PF06742.11 CCH59833.1 - 0.00024 21.5 4.0 29 5.1 0.0 4.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1214) Ribosomal_S21e PF01249.18 CCH59833.1 - 0.0029 17.7 1.8 65 3.7 0.0 4.2 3 1 0 4 4 4 0 Ribosomal protein S21e Rieske_2 PF13806.6 CCH59833.1 - 0.27 11.2 0.9 24 4.9 0.0 3.0 3 0 0 3 3 3 0 Rieske-like [2Fe-2S] domain RVT_2 PF07727.14 CCH59834.1 - 0.008 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Zn_clus PF00172.18 CCH59836.1 - 0.0062 16.6 2.3 0.0062 16.6 2.3 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ran-binding PF05508.11 CCH59837.1 - 1.5e-98 329.6 14.9 1.5e-98 329.6 14.9 1.9 2 0 0 2 2 2 1 RanGTP-binding protein Copper-fist PF00649.18 CCH59838.1 - 2.6e-20 71.6 1.9 2.6e-20 71.6 1.9 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain PBP1_TM PF14812.6 CCH59838.1 - 0.12 12.7 1.3 0.26 11.7 1.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4629 PF15442.6 CCH59838.1 - 1.7 8.9 9.2 6.4 7.0 9.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Glyco_transf_15 PF01793.16 CCH59839.1 - 3.2e-126 421.0 15.5 4e-126 420.7 15.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3405 PF11885.8 CCH59839.1 - 0.035 12.7 2.0 0.049 12.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) E1-E2_ATPase PF00122.20 CCH59840.1 - 4.8e-49 166.3 0.1 4.8e-49 166.3 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCH59840.1 - 1.2e-45 155.5 1.1 1.2e-45 155.5 1.1 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCH59840.1 - 3e-23 83.2 0.0 5.6e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH59840.1 - 2e-18 66.2 0.0 4.2e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CCH59840.1 - 1e-15 57.2 0.0 2.3e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCH59840.1 - 2.3e-05 24.2 7.0 0.00037 20.3 0.8 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Flocculin PF00624.18 CCH59841.1 - 2.7e-54 181.1 220.8 2.8e-12 46.6 15.2 27.4 24 1 2 26 26 26 10 Flocculin repeat MIP PF00230.20 CCH59842.1 - 1e-46 159.5 16.6 1.4e-46 159.1 16.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein ADH_zinc_N PF00107.26 CCH59843.1 - 9.1e-17 61.3 0.1 1.4e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CCH59843.1 - 4e-15 55.7 0.0 6.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 CCH59843.1 - 0.0027 18.8 0.0 0.0051 17.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LAB_N PF07578.11 CCH59843.1 - 0.0069 16.5 0.2 0.016 15.3 0.2 1.6 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain Epimerase PF01370.21 CCH59844.1 - 1.2e-13 51.1 0.0 2.2e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCH59844.1 - 7.3e-09 35.0 0.0 9.2e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCH59844.1 - 5.4e-07 29.7 0.0 9.7e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCH59844.1 - 1.5e-06 27.9 0.3 1.3e-05 24.8 0.3 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CCH59844.1 - 1.5e-06 27.8 0.3 0.00023 20.7 0.0 2.4 2 1 0 2 2 2 2 short chain dehydrogenase NmrA PF05368.13 CCH59844.1 - 5.9e-06 26.0 0.2 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 CCH59844.1 - 5.2e-05 22.5 0.1 0.00068 18.9 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CCH59844.1 - 0.0016 17.7 0.1 0.0039 16.4 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CCH59844.1 - 0.0045 16.9 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Fmp27 PF10344.9 CCH59844.1 - 0.017 13.3 0.0 0.022 12.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 F420_oxidored PF03807.17 CCH59844.1 - 0.023 15.3 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CCH59844.1 - 0.054 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 CCH59845.1 - 7.6e-15 55.0 0.0 1.2e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCH59845.1 - 1.8e-13 50.2 0.1 2.5e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CCH59845.1 - 2.3e-07 30.5 0.1 3.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CCH59845.1 - 2.4e-07 30.2 0.1 4.8e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CCH59845.1 - 3.5e-07 30.3 0.0 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CCH59845.1 - 1.8e-05 24.0 0.0 3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCH59845.1 - 3e-05 23.7 0.0 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 CCH59845.1 - 5e-05 22.9 0.0 0.00012 21.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Fmp27 PF10344.9 CCH59845.1 - 0.00025 19.3 0.1 0.00027 19.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 KR PF08659.10 CCH59845.1 - 0.00027 20.9 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 CCH59845.1 - 0.0066 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.17 CCH59845.1 - 0.0096 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 CCH59845.1 - 0.14 12.8 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CRC_subunit PF08624.10 CCH59846.1 - 3.6e-36 124.6 0.1 1.3e-35 122.7 0.0 2.0 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lectin_leg-like PF03388.13 CCH59847.1 - 1.1e-36 126.3 0.0 1.6e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family SnAC PF14619.6 CCH59848.1 - 0.029 15.0 0.2 0.078 13.6 0.2 1.7 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex V-SNARE_C PF12352.8 CCH59849.1 - 3.9e-08 33.5 3.7 3.9e-08 33.5 3.7 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CCH59849.1 - 0.0001 22.2 1.0 0.0001 22.2 1.0 2.2 2 1 1 3 3 3 1 Sec20 DUF4407 PF14362.6 CCH59849.1 - 0.00026 20.5 0.6 0.00036 20.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) XS PF03468.14 CCH59849.1 - 0.0029 17.9 0.8 0.0074 16.6 0.8 1.7 1 1 0 1 1 1 1 XS domain DUF1043 PF06295.12 CCH59849.1 - 0.51 10.3 11.7 2.9 7.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) RCC1 PF00415.18 CCH59850.1 - 5.8e-25 87.7 0.0 0.00035 21.1 0.0 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCH59850.1 - 7.4e-15 54.3 6.8 2e-07 30.6 0.6 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.11 CCH59851.1 - 4.4e-52 176.7 9.5 5.2e-52 176.4 9.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Mt_ATP_synt PF15704.5 CCH59851.1 - 0.0046 16.9 0.9 0.0046 16.9 0.9 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase subunit DUF5082 PF16888.5 CCH59851.1 - 0.023 14.9 7.6 0.14 12.5 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Arm-DNA-bind_2 PF12167.8 CCH59851.1 - 0.037 14.0 0.6 0.51 10.3 0.1 2.6 2 1 0 2 2 2 0 Arm DNA-binding domain Sulfatase_C PF14707.6 CCH59851.1 - 0.081 13.7 0.4 21 5.8 0.0 2.4 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase GreA_GreB_N PF03449.15 CCH59851.1 - 0.13 12.4 4.4 0.088 13.0 1.9 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Cornichon PF03311.14 CCH59851.1 - 0.2 12.0 0.9 0.28 11.5 0.1 1.6 2 0 0 2 2 2 0 Cornichon protein FTA4 PF13093.6 CCH59851.1 - 0.25 11.2 8.0 0.31 10.9 8.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 COG2 PF06148.11 CCH59851.1 - 0.33 11.0 8.8 0.16 12.1 3.5 2.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 CCH59851.1 - 0.96 9.5 5.7 2.5 8.1 0.8 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_lysis PF03245.13 CCH59851.1 - 1.1 9.4 5.6 1.1 9.4 0.8 2.3 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF1732 PF08340.11 CCH59851.1 - 1.1 9.3 8.4 2 8.5 6.5 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) DUF1664 PF07889.12 CCH59851.1 - 4.5 7.3 11.1 3.4 7.7 5.5 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L16 PF00252.18 CCH59852.1 - 9.8e-42 142.1 0.1 1.2e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e OTU PF02338.19 CCH59853.1 - 2.1e-08 34.7 0.0 3.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease FERM_N PF09379.10 CCH59853.1 - 0.016 15.1 1.2 0.11 12.4 0.2 2.7 3 0 0 3 3 3 0 FERM N-terminal domain USP8_dimer PF08969.11 CCH59854.1 - 2.8e-06 27.5 3.3 5.6e-06 26.5 3.3 1.6 1 1 0 1 1 1 1 USP8 dimerisation domain VASt PF16016.5 CCH59855.1 - 1.8e-35 122.6 0.5 1.8e-35 122.6 0.5 2.5 3 0 0 3 3 3 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCH59855.1 - 1.5e-25 89.2 0.5 4.4e-25 87.8 0.5 1.9 1 0 0 1 1 1 1 GRAM domain Med14 PF08638.11 CCH59856.1 - 6.2e-58 195.4 2.5 1.8e-57 193.9 2.5 1.9 1 0 0 1 1 1 1 Mediator complex subunit MED14 CDT1 PF08839.11 CCH59856.1 - 0.02 15.2 1.4 0.048 14.0 0.7 1.9 2 0 0 2 2 2 0 DNA replication factor CDT1 like rRNA_processing PF08524.11 CCH59857.1 - 5.2e-37 127.2 44.8 6.7e-37 126.8 44.8 1.2 1 0 0 1 1 1 1 rRNA processing PPR_2 PF13041.6 CCH59858.1 - 1.5e-07 31.5 6.3 2.8 8.2 0.0 6.7 5 3 3 8 8 8 3 PPR repeat family PPR_long PF17177.4 CCH59858.1 - 2.6e-05 23.7 2.4 0.21 10.9 0.2 4.0 2 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CCH59858.1 - 0.00083 19.5 2.1 8.5 6.9 0.1 6.5 7 0 0 7 7 7 1 PPR repeat Sugar_tr PF00083.24 CCH59859.1 - 4e-65 220.4 28.8 6e-65 219.9 28.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59859.1 - 2.2e-23 82.8 36.6 2.8e-22 79.1 23.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CCH59859.1 - 0.001 18.4 4.0 0.0019 17.6 4.0 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 CCH59859.1 - 0.0023 16.9 9.5 0.0023 16.9 9.5 3.0 3 1 0 3 3 3 1 MFS_1 like family Actin PF00022.19 CCH59860.1 - 1.2e-151 505.0 0.0 3.5e-151 503.4 0.0 1.6 1 1 0 1 1 1 1 Actin Ras PF00071.22 CCH59861.1 - 1.4e-64 216.6 0.8 1.7e-64 216.3 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH59861.1 - 2.3e-36 124.6 0.2 3.5e-36 124.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH59861.1 - 8.9e-18 64.3 0.2 1.1e-17 64.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH59861.1 - 4.7e-06 26.1 0.4 7.8e-06 25.4 0.3 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH59861.1 - 7.1e-05 22.9 0.1 0.00012 22.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH59861.1 - 9.2e-05 22.1 0.2 0.00026 20.6 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCH59861.1 - 0.0013 18.2 0.1 0.0023 17.4 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CCH59861.1 - 0.0021 18.0 1.6 0.12 12.3 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase AAA PF00004.29 CCH59861.1 - 0.012 16.0 0.1 0.28 11.6 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 CCH59861.1 - 0.028 13.7 0.1 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 CCH59861.1 - 0.046 13.5 0.1 0.31 10.8 0.1 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CCH59861.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CCH59861.1 - 0.076 13.0 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CCH59861.1 - 0.095 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CCH59861.1 - 0.11 12.1 0.2 0.52 9.8 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 CCH59861.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 CCH59861.1 - 0.14 12.4 0.1 0.35 11.1 0.0 1.9 1 1 0 2 2 2 0 AAA domain UPF0121 PF03661.13 CCH59862.1 - 2.6e-09 36.8 26.5 5.6e-09 35.7 26.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Questin_oxidase PF14027.6 CCH59862.1 - 0.086 12.4 0.5 0.12 11.9 0.5 1.2 1 0 0 1 1 1 0 Questin oxidase-like ETF_alpha PF00766.19 CCH59863.1 - 9.2e-34 115.3 0.1 1.6e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 CCH59863.1 - 3.5e-11 43.3 0.0 5.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PEGA PF08308.11 CCH59863.1 - 0.066 13.1 0.7 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 PEGA domain AAA_18 PF13238.6 CCH59864.1 - 3.4e-08 34.1 0.1 9.1e-06 26.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CCH59864.1 - 5e-05 23.3 0.0 0.00012 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCH59864.1 - 6.4e-05 23.1 0.0 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCH59864.1 - 0.00015 22.2 0.0 0.00019 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CCH59864.1 - 0.00026 21.3 0.0 0.00084 19.7 0.0 1.9 2 0 0 2 2 1 1 RNA helicase ADK PF00406.22 CCH59864.1 - 0.00038 20.6 0.4 0.62 10.2 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CCH59864.1 - 0.00058 20.3 0.1 0.014 15.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 CCH59864.1 - 0.0006 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 CCH59864.1 - 0.00077 19.0 0.2 0.0033 16.9 0.0 2.0 2 1 1 3 3 3 1 Chromatin associated protein KTI12 AAA PF00004.29 CCH59864.1 - 0.001 19.5 0.0 0.0028 18.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH59864.1 - 0.0018 18.5 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCH59864.1 - 0.0027 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 CCH59864.1 - 0.0033 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CCH59864.1 - 0.0041 17.0 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 NTPase Sigma54_activat PF00158.26 CCH59864.1 - 0.0049 16.6 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain PRK PF00485.18 CCH59864.1 - 0.0058 16.4 0.1 1.5 8.5 0.0 2.5 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CCH59864.1 - 0.0062 15.8 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin G-alpha PF00503.20 CCH59864.1 - 0.0067 15.6 3.5 0.0099 15.1 3.4 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_14 PF13173.6 CCH59864.1 - 0.0075 16.3 0.2 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CCH59864.1 - 0.0096 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase DUF5313 PF17240.2 CCH59864.1 - 0.011 16.1 0.0 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5313) RuvB_N PF05496.12 CCH59864.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 CCH59864.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 CCH59864.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 CCH59864.1 - 0.019 14.8 0.0 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 CCH59864.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CCH59864.1 - 0.019 15.4 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.20 CCH59864.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 CCH59864.1 - 0.02 14.6 0.1 0.042 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCH59864.1 - 0.027 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin2 PF13189.6 CCH59864.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family MeaB PF03308.16 CCH59864.1 - 0.034 13.1 0.0 0.087 11.8 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Guanylate_kin PF00625.21 CCH59864.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase MCM PF00493.23 CCH59864.1 - 0.04 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain MMR_HSR1 PF01926.23 CCH59864.1 - 0.046 13.8 0.2 0.12 12.4 0.1 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CCH59864.1 - 0.049 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ploopntkinase3 PF18751.1 CCH59864.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 NACHT PF05729.12 CCH59864.1 - 0.051 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 1 0 NACHT domain GTP_EFTU PF00009.27 CCH59864.1 - 0.057 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CCH59864.1 - 0.076 12.8 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 CCH59864.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 CCH59864.1 - 0.098 12.1 0.3 0.23 10.9 0.1 1.6 2 0 0 2 2 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 CCH59864.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 CCH59864.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Ribosomal_L27A PF00828.19 CCH59864.1 - 0.14 12.8 0.1 0.36 11.5 0.1 1.8 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A FtsK_SpoIIIE PF01580.18 CCH59864.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SKI PF01202.22 CCH59864.1 - 0.18 11.9 0.1 0.53 10.4 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase AAA_30 PF13604.6 CCH59864.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ICL PF00463.21 CCH59866.1 - 1.9e-171 571.1 0.4 2.2e-171 570.9 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCH59866.1 - 2.7e-09 36.8 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase KLRAQ PF10205.9 CCH59867.1 - 0.022 15.0 3.1 0.022 15.0 3.1 2.6 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein YebO PF13974.6 CCH59867.1 - 7.1 6.8 9.5 1.7 8.8 1.9 2.8 2 0 0 2 2 2 0 YebO-like protein Peptidase_M24 PF00557.24 CCH59868.1 - 5.8e-57 192.8 0.1 7.4e-57 192.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCH59868.1 - 2e-20 72.8 0.0 6.7e-20 71.1 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain UCH PF00443.29 CCH59869.1 - 1.1e-09 38.2 1.4 2.1e-09 37.2 1.5 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCH59869.1 - 4e-09 36.7 0.5 7.6e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Imm42 PF15593.6 CCH59869.1 - 1.2 9.6 6.4 3.3 8.2 0.2 2.8 3 0 0 3 3 3 0 Immunity protein 42 JAB PF01398.21 CCH59870.1 - 2.8e-32 111.2 1.4 3.1e-32 111.0 0.2 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CCH59870.1 - 2.2e-11 44.2 1.3 4.9e-11 43.0 1.3 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CCH59870.1 - 2.5e-07 30.5 0.0 4.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CCH59870.1 - 0.012 15.7 0.5 0.031 14.3 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) PPI_Ypi1 PF07491.11 CCH59871.1 - 5.3e-11 42.2 0.8 1e-10 41.2 0.8 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor CNDH2_C PF16858.5 CCH59872.1 - 0.0077 16.2 6.0 0.0093 15.9 6.0 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Hydrolase_6 PF13344.6 CCH59872.1 - 0.032 14.3 0.1 0.1 12.7 0.0 1.8 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CDI PF02234.19 CCH59872.1 - 0.51 10.6 0.2 0.51 10.6 0.2 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor DUF5601 PF18151.1 CCH59872.1 - 1.3 9.4 5.6 3.2 8.1 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) Tubulin-binding PF00418.19 CCH59873.1 - 0.026 14.5 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat PseudoU_synth_1 PF01416.20 CCH59874.1 - 5.4e-34 116.9 0.0 3.8e-31 107.8 0.0 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase DUF87 PF01935.17 CCH59874.1 - 0.93 9.5 4.6 1.2 9.2 3.7 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain Nic96 PF04097.14 CCH59876.1 - 1.9e-196 654.3 3.7 2.6e-196 653.8 3.7 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF4934 PF16288.5 CCH59876.1 - 0.021 14.8 0.1 0.61 10.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) NFACT-C PF11923.8 CCH59877.1 - 1.1e-29 102.5 0.1 1.1e-29 102.5 0.1 4.0 3 1 1 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 CCH59877.1 - 1.5e-20 73.4 0.2 1.5e-20 73.4 0.2 4.0 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CCH59877.1 - 9.5e-18 64.9 0.4 3.2e-17 63.2 0.4 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain Alpha-mann_mid PF09261.11 CCH59877.1 - 1.1 9.5 5.2 0.19 11.9 0.3 2.3 2 0 0 2 2 2 0 Alpha mannosidase middle domain Bromo_TP PF07524.13 CCH59878.1 - 0.002 18.1 0.1 0.0062 16.5 0.1 1.9 2 0 0 2 2 2 1 Bromodomain associated NUC173 PF08161.12 CCH59879.1 - 6.5e-70 234.9 1.3 2.4e-67 226.6 0.3 4.0 4 0 0 4 4 4 1 NUC173 domain HEAT PF02985.22 CCH59879.1 - 0.0003 20.8 0.1 1.2 9.6 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat RTTN_N PF14726.6 CCH59879.1 - 0.67 10.8 2.7 8.8 7.2 0.0 4.0 4 0 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning DEAD PF00270.29 CCH59880.1 - 7.7e-42 143.0 1.1 8.1e-41 139.7 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59880.1 - 6.7e-32 110.1 5.3 6.3e-28 97.3 0.1 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCH59880.1 - 4.2e-05 23.6 0.0 4.2e-05 23.6 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCH59880.1 - 0.25 11.6 1.1 3.6 7.9 1.1 2.4 1 1 0 1 1 1 0 AAA domain ATP-synt_G PF04718.15 CCH59881.1 - 6.6e-30 103.9 0.2 7.8e-30 103.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Ly-6_related PF06579.12 CCH59881.1 - 0.036 14.3 0.1 0.053 13.8 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein zf-C3Hc3H PF13891.6 CCH59881.1 - 0.077 13.4 0.1 0.13 12.7 0.1 1.3 1 0 0 1 1 1 0 Potential DNA-binding domain Mss4 PF04421.13 CCH59882.1 - 5.1e-18 65.0 1.7 1.2e-17 63.9 1.7 1.6 1 1 0 1 1 1 1 Mss4 protein eIF-6 PF01912.18 CCH59883.1 - 1.9e-81 272.2 0.3 2.4e-81 271.9 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family Pil1 PF13805.6 CCH59884.1 - 1.3e-114 382.2 1.1 1.3e-114 382.2 1.1 2.2 2 1 1 3 3 3 1 Eisosome component PIL1 Rap1_C PF11626.8 CCH59884.1 - 0.03 14.4 0.1 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PXB PF12828.7 CCH59884.1 - 0.041 13.9 0.2 0.098 12.6 0.2 1.6 1 0 0 1 1 1 0 PX-associated DEAD PF00270.29 CCH59885.1 - 6.2e-39 133.6 0.0 3.9e-38 131.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH59885.1 - 2.5e-23 82.5 0.1 1.1e-22 80.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCH59885.1 - 2.9e-15 56.2 0.0 6.7e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCH59885.1 - 8.8e-06 25.8 0.6 3.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCH59885.1 - 0.00017 20.9 0.1 0.00017 20.9 0.1 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Gp_dh_C PF02800.20 CCH59885.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain FMN_red PF03358.15 CCH59886.1 - 5.2e-10 39.3 0.2 9.2e-10 38.5 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CCH59886.1 - 9.3e-05 22.7 0.0 0.0002 21.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 CCH59886.1 - 0.00056 19.7 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Ribosomal_L32p PF01783.23 CCH59887.1 - 2.4e-15 56.5 1.0 3.5e-15 56.0 1.0 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CCH59887.1 - 0.026 13.9 2.1 0.044 13.2 2.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Endonuc-MspI PF09208.10 CCH59887.1 - 0.097 12.1 2.3 0.05 13.0 0.6 1.4 2 0 0 2 2 2 0 Restriction endonuclease MspI RecR PF02132.15 CCH59887.1 - 0.2 11.3 1.1 0.35 10.5 1.1 1.3 1 0 0 1 1 1 0 RecR protein Pkinase PF00069.25 CCH59888.1 - 9.7e-50 169.4 0.2 4.2e-49 167.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59888.1 - 1.8e-24 86.4 0.0 3.7e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCH59888.1 - 0.00099 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CCH59888.1 - 0.0073 15.7 0.0 0.027 13.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.20 CCH59888.1 - 0.008 15.8 0.1 0.008 15.8 0.1 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 CCH59888.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CCH59888.1 - 0.054 12.5 2.5 0.081 12.0 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 RIO1 PF01163.22 CCH59888.1 - 0.073 12.7 0.3 0.26 10.9 0.0 2.0 3 0 0 3 3 3 0 RIO1 family SPC25 PF06703.11 CCH59888.1 - 6.5 6.5 0.0 6.5 6.5 0.0 2.9 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) BAR PF03114.18 CCH59889.1 - 4.8e-48 163.9 2.6 5.6e-48 163.7 2.6 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CCH59889.1 - 0.0013 18.5 1.1 0.0019 17.9 1.1 1.2 1 0 0 1 1 1 1 BAR domain of APPL family DUF1496 PF07383.12 CCH59889.1 - 0.012 15.2 0.7 0.027 14.1 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) NADH_4Fe-4S PF10589.9 CCH59889.1 - 0.2 11.7 0.6 12 6.1 0.0 2.8 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Gpr1_Fun34_YaaH PF01184.19 CCH59890.1 - 1.7e-88 295.7 18.0 2e-88 295.4 18.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF997 PF06196.12 CCH59890.1 - 0.42 10.7 4.3 5.5 7.1 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF4448 PF14610.6 CCH59892.1 - 1.1e-49 168.8 0.2 6.9e-29 101.0 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) ThiD2 PF17792.1 CCH59892.1 - 6e-08 33.2 54.4 0.75 10.3 0.4 10.3 2 1 13 15 15 15 9 ThiD2 family PDEase_I PF00233.19 CCH59892.1 - 6.7e-07 29.3 35.5 1.2 8.9 0.9 8.0 1 1 2 3 3 2 2 3'5'-cyclic nucleotide phosphodiesterase MOR2-PAG1_C PF14225.6 CCH59892.1 - 3.3e-05 23.9 15.3 17 5.1 0.4 8.4 1 1 7 8 8 8 0 Cell morphogenesis C-terminal THDPS_N_2 PF14805.6 CCH59892.1 - 3.5e-05 23.9 43.7 40 4.5 0.1 15.6 4 3 10 16 16 16 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal MIP-T3 PF10243.9 CCH59892.1 - 5.7e-05 23.1 66.0 0.64 10.0 2.0 9.5 1 1 10 11 11 11 8 Microtubule-binding protein MIP-T3 CH-like domain PPP5 PF08321.12 CCH59892.1 - 0.14 12.5 49.6 15 6.0 1.4 12.1 1 1 7 8 8 8 0 PPP5 TPR repeat region CsgA PF17334.2 CCH59892.1 - 0.35 11.6 33.4 73 4.2 0.4 10.7 1 1 12 15 15 15 0 Minor curli fiber component A Ntox34 PF15606.6 CCH59892.1 - 1.3 9.2 36.4 0.3 11.2 0.4 8.3 1 1 6 9 9 9 0 Bacterial toxin 34 TetR_C_23 PF17931.1 CCH59892.1 - 1.6 8.9 57.9 42 4.3 0.4 13.2 2 1 19 21 21 21 0 Tetracyclin repressor-like, C-terminal domain AAA_16 PF13191.6 CCH59892.1 - 3 8.2 33.8 38 4.6 3.1 6.4 1 1 4 5 5 5 0 AAA ATPase domain Med23 PF11573.8 CCH59892.1 - 4.3 4.8 29.3 1.4 6.5 5.1 4.4 1 1 2 4 4 4 0 Mediator complex subunit 23 6PGD PF00393.19 CCH59892.1 - 6.3 6.1 22.5 16 4.7 2.0 6.2 1 1 6 7 7 7 0 6-phosphogluconate dehydrogenase, C-terminal domain Sen15 PF09631.10 CCH59893.1 - 1.6e-19 70.0 0.0 1.9e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein ArgJ PF01960.18 CCH59894.1 - 1.3e-139 465.1 7.8 1.5e-139 464.9 7.8 1.0 1 0 0 1 1 1 1 ArgJ family Myco_19_kDa PF05481.12 CCH59894.1 - 0.053 13.8 0.2 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen TraI_2B PF18340.1 CCH59894.1 - 0.061 13.4 0.7 0.27 11.3 0.1 2.3 2 0 0 2 2 2 0 DNA relaxase TraI 2B/2B-like domain Kinesin PF00225.23 CCH59895.1 - 5e-52 176.9 10.7 5e-52 176.9 10.7 1.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CCH59895.1 - 2.2e-14 53.6 9.1 6.5e-12 45.6 1.0 3.1 2 1 1 3 3 3 2 Microtubule binding EF1G PF00647.19 CCH59896.1 - 4.3e-46 155.4 1.3 6.8e-46 154.7 0.1 2.0 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CCH59896.1 - 5.7e-11 42.6 0.1 4.8e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCH59896.1 - 6.9e-11 42.2 2.9 7.5e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCH59896.1 - 0.00073 19.7 0.2 0.00073 19.7 0.2 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH59896.1 - 0.0014 18.6 0.1 0.003 17.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 CCH59896.1 - 0.43 10.1 4.5 0.63 9.6 4.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EF1G PF00647.19 CCH59897.1 - 2.6e-46 156.1 0.1 6.8e-46 154.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CCH59897.1 - 5.1e-13 49.1 0.2 5.1e-13 49.1 0.2 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCH59897.1 - 3.1e-12 46.6 0.0 1.2e-11 44.7 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCH59897.1 - 0.00021 21.3 0.1 0.00057 19.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCH59897.1 - 0.00042 20.7 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF4817 PF16087.5 CCH59897.1 - 0.2 11.5 0.2 2 8.3 0.1 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) SR-25 PF10500.9 CCH59897.1 - 0.72 9.4 5.7 1.1 8.9 5.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TUG-UBL1 PF11470.8 CCH59898.1 - 2.2e-17 63.0 13.5 8.9e-17 61.1 0.7 3.8 5 0 0 5 5 5 2 TUG ubiquitin-like domain UBX PF00789.20 CCH59898.1 - 6.4e-11 42.3 0.2 3.8e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.8 CCH59898.1 - 0.032 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Formin_GBD_N PF18382.1 CCH59898.1 - 2.1 8.9 6.3 1.4 9.4 0.2 3.4 3 2 0 4 4 4 0 Formin N-terminal GTPase-binding domain zf-CHY PF05495.12 CCH59899.1 - 7.9e-14 51.9 14.9 7.9e-14 51.9 14.9 1.5 2 0 0 2 2 2 1 CHY zinc finger IBR PF01485.21 CCH59899.1 - 0.004 17.3 5.2 0.004 17.3 5.2 2.4 1 1 1 2 2 2 1 IBR domain, a half RING-finger domain zinc_ribbon_9 PF14369.6 CCH59899.1 - 0.008 16.4 10.5 1.6 9.1 3.1 3.0 1 1 1 2 2 2 2 zinc-ribbon DUF1451 PF07295.11 CCH59899.1 - 0.048 13.7 1.7 0.048 13.7 1.7 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain Zn-ribbon_8 PF09723.10 CCH59899.1 - 0.11 12.6 0.8 0.11 12.6 0.8 2.6 2 1 0 2 2 2 0 Zinc ribbon domain HypA PF01155.19 CCH59899.1 - 0.29 11.2 8.1 0.18 11.8 4.3 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CCH59899.1 - 1 9.4 15.8 10 6.2 15.8 2.4 1 1 0 1 1 1 0 Double zinc ribbon Cytochrome_C7 PF14522.6 CCH59899.1 - 1.6 8.8 15.0 9 6.4 15.0 2.2 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Ldh_1_C PF02866.18 CCH59900.1 - 4.2e-49 166.7 0.0 9.7e-49 165.5 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCH59900.1 - 7e-45 152.6 0.0 9.8e-45 152.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CCH59900.1 - 0.00045 19.3 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCH59900.1 - 0.053 14.0 0.0 0.68 10.4 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.16 CCH59900.1 - 0.46 10.0 1.6 4.6 6.8 0.4 2.6 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase G-alpha PF00503.20 CCH59901.1 - 2.1e-101 339.7 0.0 2.8e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CCH59901.1 - 5.3e-14 52.0 0.2 4.3e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH59901.1 - 0.08 12.3 0.2 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DAP3 PF10236.9 CCH59901.1 - 0.22 10.7 0.3 0.34 10.0 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Cyto_heme_lyase PF01265.17 CCH59902.1 - 7.2e-34 117.7 6.9 2.9e-31 109.2 6.9 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-Tim10_DDP PF02953.15 CCH59903.1 - 6.5e-20 70.5 1.9 8.1e-20 70.2 1.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CCH59903.1 - 0.017 14.8 2.0 0.021 14.5 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Flavoprotein PF02441.19 CCH59904.1 - 2.4e-49 167.1 0.3 5.1e-49 166.0 0.3 1.6 1 0 0 1 1 1 1 Flavoprotein Ydc2-catalyt PF09159.10 CCH59906.1 - 2.9e-46 158.5 0.3 4.5e-46 157.8 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Peptidase_S24 PF00717.23 CCH59907.1 - 1.7e-09 37.5 0.0 2.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like FF PF01846.19 CCH59908.1 - 1.3e-33 115.0 16.2 7.6e-12 45.2 0.0 6.8 7 0 0 7 7 7 3 FF domain WW PF00397.26 CCH59908.1 - 6.3e-20 71.0 8.3 6.7e-10 38.9 0.6 2.6 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 CCH59908.1 - 0.055 13.8 9.1 0.21 11.9 0.5 3.2 2 2 2 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain SRP1_TIP1 PF00660.17 CCH59908.1 - 0.096 12.8 1.8 0.43 10.7 0.1 2.8 3 0 0 3 3 3 0 Seripauperin and TIP1 family Fungal_trans PF04082.18 CCH59909.1 - 2e-13 50.0 6.7 2e-13 50.0 6.7 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Mt_ATP-synt_D PF05873.12 CCH59910.1 - 4.1e-18 65.7 8.4 5.1e-18 65.4 8.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Arginosuc_synth PF00764.19 CCH59910.1 - 0.0024 17.2 0.2 0.02 14.2 0.2 2.0 1 1 0 1 1 1 1 Arginosuccinate synthase Aida_N PF08910.10 CCH59910.1 - 0.57 10.6 4.7 0.3 11.5 1.6 1.9 1 1 1 2 2 2 0 Aida N-terminus AAA_12 PF13087.6 CCH59911.1 - 9.3e-59 198.4 1.9 1.6e-58 197.6 0.1 2.3 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 CCH59911.1 - 2.8e-52 178.1 1.2 9.2e-52 176.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH59911.1 - 1.3e-11 44.6 0.0 5.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCH59911.1 - 2.3e-11 44.2 0.0 1.6e-10 41.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CCH59911.1 - 1.6e-07 31.3 0.2 0.056 13.2 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCH59911.1 - 1.8e-06 28.1 0.0 1.8e-05 24.8 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CCH59911.1 - 1e-05 25.3 0.0 5.9e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CCH59911.1 - 3e-05 24.3 0.0 0.00079 19.7 0.1 3.1 2 1 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 CCH59911.1 - 6.8e-05 22.8 0.0 0.00082 19.3 0.0 2.7 3 0 0 3 3 2 1 Helicase PIF1 PF05970.14 CCH59911.1 - 0.0008 18.7 0.4 0.11 11.6 0.0 3.0 3 0 0 3 3 3 1 PIF1-like helicase PhoH PF02562.16 CCH59911.1 - 0.0014 18.1 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 CCH59911.1 - 0.0018 18.0 0.0 0.0057 16.4 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 CCH59911.1 - 0.0024 18.3 0.5 0.021 15.2 0.3 2.6 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 CCH59911.1 - 0.0041 16.1 0.0 0.0097 14.9 0.0 1.6 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.9 CCH59911.1 - 0.0044 16.3 0.2 0.062 12.5 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF853 PF05872.12 CCH59911.1 - 0.0051 15.5 0.0 0.0085 14.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 CCH59911.1 - 0.0096 16.3 0.0 0.038 14.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 CCH59911.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.9 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_14 PF13173.6 CCH59911.1 - 0.015 15.4 0.1 0.49 10.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CCH59911.1 - 0.02 14.8 0.2 6 6.7 0.0 2.6 1 1 1 2 2 2 0 Rad17 P-loop domain T2SSE PF00437.20 CCH59911.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 CCH59911.1 - 0.023 14.4 0.1 0.17 11.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CCH59911.1 - 0.035 14.2 0.0 0.14 12.3 0.0 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU_D2 PF03144.25 CCH59911.1 - 0.039 14.3 0.5 6.2 7.3 0.0 3.1 3 1 0 3 3 2 0 Elongation factor Tu domain 2 UvrD_C PF13361.6 CCH59911.1 - 0.063 12.6 8.2 0.2 11.0 0.1 3.3 1 1 2 3 3 3 0 UvrD-like helicase C-terminal domain Flavi_DEAD PF07652.14 CCH59911.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_5 PF07728.14 CCH59911.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CCH59911.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CCH59911.1 - 0.13 11.2 0.0 0.37 9.7 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CCH59911.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CCH59912.1 - 1.2e-10 41.8 0.1 0.085 13.8 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH59912.1 - 9.9e-06 25.8 0.0 1.1 9.6 0.0 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CCH59912.1 - 0.0058 15.9 0.0 0.024 13.9 0.0 2.1 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Frtz PF11768.8 CCH59912.1 - 0.13 10.5 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF1748 PF08520.10 CCH59913.1 - 7.6e-13 48.2 0.1 8.9e-13 47.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.32 CCH59914.1 - 2.7e-24 85.0 3.7 1.1e-06 29.3 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 CCH59914.1 - 1.7e-07 30.3 3.0 0.0046 15.7 0.1 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCH59914.1 - 2.3e-07 31.0 2.4 0.77 10.1 0.0 5.3 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CCH59914.1 - 1.3e-05 24.2 4.4 0.3 9.8 0.0 4.2 2 2 2 4 4 4 4 Nup133 N terminal like BBS2_Mid PF14783.6 CCH59914.1 - 0.0036 17.3 3.0 6.8 6.8 0.3 4.2 3 2 2 5 5 5 3 Ciliary BBSome complex subunit 2, middle region AlaDh_PNT_N PF05222.15 CCH59915.1 - 4e-29 101.7 0.0 5.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CCH59915.1 - 4.6e-05 22.8 0.0 0.0016 17.8 0.0 2.4 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain EKAL PF17986.1 CCH59915.1 - 0.085 12.9 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 EMP3-KAHRP-like N-terminal domain TPR_1 PF00515.28 CCH59916.1 - 3.6e-28 96.2 16.1 2.4e-06 27.1 0.1 9.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 CCH59916.1 - 4.5e-26 88.8 4.2 0.00063 19.7 0.0 9.1 10 0 0 10 10 10 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH59916.1 - 7e-22 77.5 8.1 3e-18 65.8 0.0 4.8 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CCH59916.1 - 2.3e-19 67.9 14.8 0.16 12.3 0.2 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59916.1 - 1.8e-18 66.6 2.3 1.1e-07 32.1 0.0 7.7 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCH59916.1 - 6.4e-15 55.4 0.0 0.064 13.8 0.0 6.4 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH59916.1 - 3.6e-12 45.7 10.1 0.056 13.1 0.0 8.0 6 1 1 7 7 7 4 TPR repeat TPR_7 PF13176.6 CCH59916.1 - 2.6e-10 39.6 4.4 0.35 11.0 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCH59916.1 - 5.5e-09 35.8 8.0 0.093 13.2 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH59916.1 - 1.7e-07 31.4 0.0 9.2 7.4 0.0 6.7 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCH59916.1 - 3.7e-07 29.8 0.3 3.7 7.6 0.0 6.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCH59916.1 - 1.9e-06 28.2 1.2 6.7 7.6 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCH59916.1 - 6.9e-06 26.1 0.0 0.022 14.9 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCH59916.1 - 4e-05 24.2 0.0 4.1 8.1 0.0 5.4 7 0 0 7 7 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CCH59916.1 - 0.001 19.1 3.5 2.2 8.3 0.0 4.0 3 1 0 3 3 3 1 Putative TPR-like repeat Fis1_TPR_C PF14853.6 CCH59916.1 - 0.0016 18.4 6.9 4.5 7.4 0.3 5.5 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ADK PF00406.22 CCH59918.1 - 6.7e-48 162.6 0.0 1e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCH59918.1 - 1.1e-35 123.0 0.0 1.8e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH59918.1 - 6e-07 30.1 0.0 1.2e-06 29.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CCH59918.1 - 8.4e-07 28.8 0.5 0.013 15.2 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CCH59918.1 - 0.00039 20.6 0.0 0.012 15.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 CCH59918.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CCH59918.1 - 0.07 12.4 0.1 0.23 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 CCH59918.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MFS_1 PF07690.16 CCH59919.1 - 5.3e-11 42.0 45.7 2.5e-09 36.5 45.2 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.9 CCH59919.1 - 1.1 9.5 10.3 0.089 13.0 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Gpr1_Fun34_YaaH PF01184.19 CCH59920.1 - 3.2e-90 301.3 19.9 3.9e-90 301.0 19.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Pox_Ag35 PF03286.14 CCH59920.1 - 3.5 7.4 8.5 8.1 6.2 8.7 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Gpr1_Fun34_YaaH PF01184.19 CCH59921.1 - 1.9e-92 308.6 20.2 2.2e-92 308.3 20.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RNA_pol_Rpc34 PF05158.12 CCH59922.1 - 8.9e-108 360.6 3.9 9.9e-108 360.5 3.9 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit OHA PF14418.6 CCH59922.1 - 0.0086 15.9 0.1 0.023 14.5 0.1 1.7 1 0 0 1 1 1 1 OST-HTH Associated domain Rrf2 PF02082.20 CCH59922.1 - 0.019 15.3 1.0 0.054 13.8 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator STPPase_N PF16891.5 CCH59922.1 - 0.027 14.9 0.2 0.21 12.1 0.1 2.4 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain HAD PF12710.7 CCH59923.1 - 4.7e-05 23.9 0.0 0.0014 19.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 CCH59924.1 - 1.9e-96 323.7 27.4 2.7e-96 323.2 27.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59924.1 - 2.6e-25 89.1 28.1 3.4e-21 75.6 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3439 PF11921.8 CCH59924.1 - 0.72 9.8 4.9 1.9 8.5 4.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.24 CCH59925.1 - 1.4e-96 324.1 30.5 2e-96 323.6 30.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH59925.1 - 1.6e-29 103.0 28.6 1.4e-26 93.3 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.9 CCH59926.1 - 6.5e-26 91.2 19.8 6.5e-26 91.2 19.8 4.3 3 3 0 3 3 3 1 Frag1/DRAM/Sfk1 family VPS53_C PF16854.5 CCH59926.1 - 0.027 14.4 2.6 0.095 12.6 0.6 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus Exo_endo_phos PF03372.23 CCH59926.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family AOX PF01786.17 CCH59926.1 - 0.2 11.2 0.5 0.42 10.2 0.5 1.4 1 0 0 1 1 1 0 Alternative oxidase Zn_clus PF00172.18 CCH59927.1 - 2.3e-07 30.8 6.9 5.6e-07 29.6 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC1 PF03109.16 CCH59928.1 - 9.1e-33 112.9 0.6 2.7e-32 111.4 0.1 2.0 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.22 CCH59928.1 - 0.00014 21.6 0.0 0.00069 19.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 CCH59928.1 - 0.055 12.8 0.3 8.8 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein kinase domain TP_methylase PF00590.20 CCH59930.1 - 2e-23 83.5 0.0 2.9e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases MFS_1 PF07690.16 CCH59931.1 - 7.5e-31 107.3 52.9 1.6e-30 106.3 49.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH59931.1 - 0.00027 19.9 12.6 0.00027 19.9 12.6 3.5 2 2 1 3 3 3 1 Sugar (and other) transporter DUF2427 PF10348.9 CCH59931.1 - 0.0052 16.6 6.9 0.13 12.1 1.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) Sigma_M_inh PF17453.2 CCH59931.1 - 0.026 15.0 0.4 0.026 15.0 0.4 4.0 2 1 2 4 4 4 0 Sigma-M inhibitor Ac76 PF05814.11 CCH59931.1 - 0.21 11.6 1.4 0.81 9.7 1.4 2.0 1 0 0 1 1 1 0 Orf76 (Ac76) CAAD PF14159.6 CCH59931.1 - 0.34 10.8 5.2 21 5.0 0.0 3.8 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase WHIM1 PF15612.6 CCH59932.1 - 3.5e-05 23.2 0.1 0.00011 21.6 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SNARE PF05739.19 CCH59933.1 - 6.1e-15 54.9 0.3 6.1e-15 54.9 0.3 1.9 2 0 0 2 2 2 1 SNARE domain DUF2703 PF10865.8 CCH59933.1 - 1.1 9.4 4.0 1 9.5 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2703) DUF4404 PF14357.6 CCH59933.1 - 5.8 7.6 9.3 3.9 8.2 0.8 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1690 PF07956.11 CCH59934.1 - 2.5e-37 128.4 6.9 2.9e-37 128.2 6.9 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.13 CCH59934.1 - 0.05 13.7 0.3 0.085 13.0 0.3 1.4 1 0 0 1 1 1 0 CHCH domain DUF2733 PF10813.8 CCH59934.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) UCH PF00443.29 CCH59935.1 - 4.2e-51 173.9 1.6 5.6e-51 173.5 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH59935.1 - 7.8e-12 45.4 17.5 1.7e-11 44.3 12.6 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CCH59935.1 - 5.5e-09 35.6 0.2 4.1e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 CCH59935.1 - 0.077 12.9 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain AA_permease PF00324.21 CCH59936.1 - 6.5e-120 400.9 43.6 8e-120 400.6 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH59936.1 - 2.8e-34 118.7 43.7 3.4e-34 118.4 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.27 CCH59937.1 - 1.3e-46 158.5 0.2 1.1e-22 81.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCH59937.1 - 6.5e-21 74.2 8.5 6.5e-21 74.2 8.5 3.0 4 1 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 CCH59937.1 - 3e-18 66.7 3.2 0.00021 21.2 0.0 5.3 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH59937.1 - 7.3e-11 41.9 0.4 0.0086 15.5 0.4 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCH59937.1 - 1.2e-06 29.0 0.1 0.099 13.0 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CCH59937.1 - 1.5e-06 28.2 0.1 0.081 12.8 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CCH59937.1 - 1.8e-06 27.6 0.1 0.088 12.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH59937.1 - 5.8e-06 26.6 1.9 0.14 12.4 0.1 3.5 3 2 0 3 3 2 2 AAA domain NACHT PF05729.12 CCH59937.1 - 8.9e-06 25.7 0.1 0.047 13.6 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 CCH59937.1 - 9.5e-06 26.0 2.8 0.098 12.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 CCH59937.1 - 1.4e-05 25.5 0.0 0.05 14.0 0.1 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CCH59937.1 - 2.8e-05 24.1 0.6 0.12 12.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 CCH59937.1 - 4.3e-05 23.6 0.0 0.58 10.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 CCH59937.1 - 5.6e-05 22.9 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 CCH59937.1 - 0.00021 21.1 26.5 0.012 15.3 0.0 4.6 3 1 1 4 4 3 2 AAA ATPase domain PduV-EutP PF10662.9 CCH59937.1 - 0.00026 20.8 1.5 0.25 11.1 0.1 3.5 4 0 0 4 4 3 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 CCH59937.1 - 0.00031 20.9 1.5 0.3 11.2 0.0 3.1 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.22 CCH59937.1 - 0.00033 19.9 0.6 0.13 11.5 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 CCH59937.1 - 0.00041 20.9 29.9 0.13 12.7 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 CCH59937.1 - 0.00047 20.7 8.4 0.23 12.0 0.1 4.7 5 1 0 5 5 4 2 AAA domain AAA_24 PF13479.6 CCH59937.1 - 0.00065 19.5 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCH59937.1 - 0.00066 20.0 0.0 0.74 10.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CCH59937.1 - 0.0012 18.4 0.1 0.25 10.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 CCH59937.1 - 0.0014 18.9 0.1 1.6 9.0 0.1 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CCH59937.1 - 0.0018 18.3 0.0 0.24 11.4 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CCH59937.1 - 0.0047 16.1 0.0 2.9 7.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CCH59937.1 - 0.0049 16.2 0.0 1.5 8.0 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 CCH59937.1 - 0.0051 16.5 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.14 CCH59937.1 - 0.007 16.3 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 CCH59937.1 - 0.01 15.8 2.1 4.7 7.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) MeaB PF03308.16 CCH59937.1 - 0.011 14.8 0.0 0.86 8.5 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CCH59937.1 - 0.011 15.4 0.0 1.2 8.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 CCH59937.1 - 0.017 14.4 0.4 6.8 5.9 0.0 2.8 2 1 0 2 2 2 0 Septin FeoB_N PF02421.18 CCH59937.1 - 0.018 14.5 0.1 4.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Pox_A32 PF04665.12 CCH59937.1 - 0.019 14.4 0.1 0.55 9.6 0.0 2.6 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.19 CCH59937.1 - 0.02 14.5 0.1 3.5 7.2 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 CCH59937.1 - 0.02 14.5 0.1 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 CCH59937.1 - 0.021 14.0 4.3 0.65 9.1 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit NTPase_1 PF03266.15 CCH59937.1 - 0.023 14.6 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 NTPase MCM PF00493.23 CCH59937.1 - 0.042 12.9 0.0 0.95 8.5 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain SbcCD_C PF13558.6 CCH59937.1 - 0.046 13.9 0.0 29 5.0 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 CCH59937.1 - 0.14 12.0 8.7 0.15 12.0 0.0 3.2 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 CCH59937.1 - 0.19 11.1 0.3 9.9 5.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2813 PF11398.8 CCH59937.1 - 0.31 10.2 0.0 0.31 10.2 0.0 3.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2813) FtsK_SpoIIIE PF01580.18 CCH59937.1 - 0.41 9.9 2.5 2 7.7 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family Helo_like_N PF17111.5 CCH59937.1 - 0.86 8.9 8.6 4.1 6.7 1.2 3.9 4 1 1 5 5 4 0 Fungal N-terminal domain of STAND proteins DUF87 PF01935.17 CCH59937.1 - 1.3 9.0 0.0 1.3 9.0 0.0 4.8 4 1 1 5 5 5 0 Helicase HerA, central domain AAA_17 PF13207.6 CCH59937.1 - 1.8 9.0 8.1 37 4.7 0.1 4.4 3 1 0 4 4 4 0 AAA domain PhageMin_Tail PF10145.9 CCH59937.1 - 3.9 7.3 5.6 2.8 7.7 0.2 2.3 2 0 0 2 2 2 0 Phage-related minor tail protein LMBR1 PF04791.16 CCH59937.1 - 7.3 5.4 10.9 6.9 5.5 1.2 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein AA_permease PF00324.21 CCH59939.1 - 6.7e-133 443.8 32.4 7.9e-133 443.5 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH59939.1 - 6.9e-27 94.3 34.0 9.2e-27 93.9 34.0 1.2 1 0 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.12 CCH59939.1 - 0.49 10.6 6.6 0.43 10.8 0.9 2.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Aminotran_5 PF00266.19 CCH59940.1 - 7.1e-99 331.2 0.0 8.8e-99 330.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCH59940.1 - 3.4e-09 36.5 0.2 1.1e-07 31.6 0.2 2.4 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CCH59940.1 - 1.3e-07 31.2 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CCH59940.1 - 2.9e-07 30.0 0.0 4.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 CCH59940.1 - 0.00077 18.3 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CCH59940.1 - 0.0054 15.3 0.3 0.0083 14.7 0.3 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TssC PF17541.2 CCH59940.1 - 0.033 13.0 0.1 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB 4_1_CTD PF05902.13 CCH59940.1 - 0.27 11.3 5.5 0.048 13.7 1.5 1.8 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) Mito_carr PF00153.27 CCH59941.1 - 4.5e-48 161.1 9.3 7.9e-18 64.2 0.2 4.1 2 2 2 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 CCH59941.1 - 0.0028 16.9 0.1 0.0028 16.9 0.1 2.8 2 1 1 3 3 3 1 Gammaproteobacterial serine protease Dcc1 PF09724.9 CCH59942.1 - 1.6e-76 257.8 0.4 1.9e-76 257.5 0.4 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 ETS_PEA3_N PF04621.13 CCH59942.1 - 0.031 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain ICA69 PF04629.14 CCH59942.1 - 0.13 12.6 0.6 0.84 9.9 0.2 2.1 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain DUF3507 PF12015.8 CCH59943.1 - 2.6e-36 125.1 3.0 1.1e-35 123.0 3.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) ASFV_J13L PF05568.11 CCH59943.1 - 0.36 10.5 3.6 0.56 9.9 2.5 1.8 1 1 0 1 1 1 0 African swine fever virus J13L protein Iso_dh PF00180.20 CCH59944.1 - 1.4e-67 228.3 0.0 1.6e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Flavodoxin_2 PF02525.17 CCH59945.1 - 6.8e-54 182.6 0.1 8.4e-54 182.3 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCH59945.1 - 5.5e-14 52.2 0.0 8.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 CCH59945.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin PRESAN PF09687.10 CCH59945.1 - 0.05 14.2 0.3 0.083 13.4 0.3 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal UPF0052 PF01933.18 CCH59946.1 - 2.8e-64 217.2 0.2 3.5e-64 216.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Saf_2TM PF18303.1 CCH59946.1 - 0.0025 17.4 0.2 0.0079 15.8 0.0 1.8 2 0 0 2 2 2 1 SAVED-fused 2TM effector domain Pkinase PF00069.25 CCH59947.1 - 1.2e-60 205.2 0.1 3.1e-60 203.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59947.1 - 1.6e-21 76.7 0.0 2.7e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59947.1 - 1.2e-08 34.6 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCH59947.1 - 1.3e-05 24.2 0.1 6e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCH59947.1 - 8.4e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH59947.1 - 0.036 14.0 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNF2_N PF00176.23 CCH59948.1 - 7.1e-51 173.0 0.1 1.3e-50 172.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 CCH59948.1 - 2.8e-09 36.7 9.8 5.9e-09 35.7 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH59948.1 - 1e-08 34.8 7.6 2e-08 34.0 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH59948.1 - 1.8e-08 34.5 9.0 4.3e-08 33.3 9.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCH59948.1 - 1.1e-07 31.6 6.6 2.5e-07 30.5 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH59948.1 - 6.1e-06 26.2 6.0 2.7e-05 24.1 6.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCH59948.1 - 1.1e-05 25.2 7.5 2.7e-05 24.0 7.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CCH59948.1 - 0.00015 22.0 5.5 0.00046 20.4 5.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CCH59948.1 - 0.00037 20.3 6.0 0.00079 19.2 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCH59948.1 - 0.00087 19.4 9.0 0.0017 18.4 9.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CCH59948.1 - 0.0048 16.9 2.1 0.011 15.8 2.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Helicase_C PF00271.31 CCH59948.1 - 0.045 14.1 0.1 0.045 14.1 0.1 4.6 5 0 0 5 5 3 0 Helicase conserved C-terminal domain zf-Nse PF11789.8 CCH59948.1 - 0.054 13.3 2.9 0.17 11.7 2.9 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 CCH59948.1 - 0.35 10.5 6.3 0.72 9.5 6.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CCH59948.1 - 0.94 9.4 3.7 2.1 8.3 3.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CCH59948.1 - 4.8 7.0 13.3 0.082 12.7 5.8 2.1 2 0 0 2 2 1 0 RING-like zinc finger zf-RING_4 PF14570.6 CCH59948.1 - 6.5 6.6 8.0 14 5.6 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Methyltransf_25 PF13649.6 CCH59950.1 - 2.2e-13 50.7 0.0 3.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH59950.1 - 9.1e-11 42.3 0.0 1.4e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH59950.1 - 1.4e-10 41.2 0.0 1.7e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH59950.1 - 9.2e-09 36.0 0.0 2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH59950.1 - 2.1e-07 30.5 0.2 3.8e-07 29.7 0.2 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CCH59950.1 - 3.7e-07 29.8 0.1 6.4e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.7 CCH59950.1 - 8.9e-06 25.7 0.1 1.7e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH59950.1 - 6e-05 22.9 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCH59950.1 - 0.00023 20.8 0.1 0.00057 19.5 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CCH59950.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_5 PF01795.19 CCH59950.1 - 0.003 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family Methyltransf_16 PF10294.9 CCH59950.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase DOT1 PF08123.13 CCH59950.1 - 0.014 14.9 0.2 0.086 12.4 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.10 CCH59950.1 - 0.077 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 CCH59950.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CCH59951.1 - 1.8e-11 44.6 0.0 4.4e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH59951.1 - 5.4e-10 39.8 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH59951.1 - 2e-09 38.1 0.1 4.8e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH59951.1 - 1.5e-08 34.5 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH59951.1 - 4.3e-05 23.0 0.0 8.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CCH59951.1 - 0.00062 19.6 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH59951.1 - 0.017 14.4 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CCH59951.1 - 0.029 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 CCH59951.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 CCH59951.1 - 0.041 12.9 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.17 CCH59951.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_5 PF01795.19 CCH59951.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Oxidored_FMN PF00724.20 CCH59952.1 - 1.1e-125 419.5 0.0 1.2e-125 419.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Alpha-amylase_C PF02806.18 CCH59953.1 - 4.9e-26 91.0 0.0 2.4e-25 88.8 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CCH59953.1 - 2.7e-16 59.7 0.2 6.7e-16 58.4 0.2 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CCH59953.1 - 5.9e-15 55.7 0.2 5.9e-15 55.7 0.2 3.1 2 2 1 3 3 3 1 Alpha amylase, catalytic domain Glyco_hydro_66 PF13199.6 CCH59953.1 - 0.0043 15.8 0.0 0.0074 15.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 AMPK1_CBM PF16561.5 CCH59953.1 - 0.045 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Aminotran_5 PF00266.19 CCH59953.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V RabGAP-TBC PF00566.18 CCH59955.1 - 2.4e-17 63.3 2.0 3.5e-17 62.8 2.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 CCH59956.1 - 4.2e-05 23.3 0.2 0.0064 16.3 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CCH59956.1 - 0.024 14.3 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated BRAP2 PF07576.12 CCH59956.1 - 0.16 12.2 0.7 16 5.8 0.0 2.8 2 0 0 2 2 2 0 BRCA1-associated protein 2 HSP70 PF00012.20 CCH59957.1 - 7.1e-34 117.0 8.6 7.1e-34 117.0 8.6 2.5 2 1 0 2 2 2 1 Hsp70 protein DUF4482 PF14818.6 CCH59957.1 - 0.0084 17.0 2.2 0.0084 17.0 2.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4482) SlyX PF04102.12 CCH59957.1 - 0.52 11.0 3.1 5.3 7.7 0.3 3.2 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 CCH59958.1 - 1.4e-303 1008.9 4.0 1.6e-303 1008.7 4.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HC2 PF07382.11 CCH59959.1 - 0.51 10.4 12.6 0.86 9.7 12.6 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ATP_synt_H PF05493.13 CCH59960.1 - 1.7e-19 70.0 3.6 2.1e-19 69.7 3.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit H MFS_2 PF13347.6 CCH59960.1 - 0.0024 16.5 0.6 0.0025 16.4 0.6 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Git3 PF11710.8 CCH59960.1 - 0.0027 17.5 0.9 0.0027 17.5 0.9 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Fungus-induced PF10917.8 CCH59960.1 - 0.032 14.5 0.1 0.051 13.9 0.1 1.4 1 0 0 1 1 1 0 Fungus-induced protein DUF3429 PF11911.8 CCH59960.1 - 0.038 14.3 2.9 0.041 14.2 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) DUF3624 PF12292.8 CCH59960.1 - 0.12 12.8 2.5 0.18 12.2 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) DUF4131 PF13567.6 CCH59960.1 - 0.22 11.2 2.5 0.23 11.1 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) UEV PF05743.13 CCH59961.1 - 3.5e-28 97.9 0.1 7.1e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CCH59961.1 - 1.9e-23 82.2 1.3 2.9e-21 75.2 1.1 2.9 3 0 0 3 3 3 1 Vps23 core domain UQ_con PF00179.26 CCH59961.1 - 3.3e-05 23.6 0.3 3.3e-05 23.6 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme DKCLD PF08068.12 CCH59962.1 - 6.3e-32 109.4 0.3 6.7e-31 106.1 0.5 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CCH59962.1 - 2.8e-23 81.8 0.3 5.6e-23 80.9 0.3 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CCH59962.1 - 8.2e-20 70.6 1.2 1.6e-19 69.6 1.2 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CCH59962.1 - 1.7e-19 70.7 10.9 4.8e-19 69.2 0.0 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CCH59962.1 - 0.014 15.6 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain CENP-N PF05238.13 CCH59962.1 - 0.16 11.3 12.3 0.21 10.9 12.3 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like GAGA_bind PF06217.12 CCH59962.1 - 2 8.6 20.5 2.9 8.1 20.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family EOS1 PF12326.8 CCH59962.1 - 4 7.4 6.5 7.4 6.5 6.5 1.6 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 CCH59962.1 - 5.7 6.7 30.0 11 5.8 30.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DnaJ_C PF01556.18 CCH59963.1 - 2.7e-35 121.7 0.1 3.5e-35 121.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCH59963.1 - 2.8e-23 81.8 0.2 5.3e-23 80.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain RFX_DNA_binding PF02257.15 CCH59964.1 - 6e-31 106.9 0.0 1.4e-30 105.7 0.0 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain RAP1 PF07218.11 CCH59964.1 - 0.81 7.9 11.5 1.6 6.9 11.5 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Iso_dh PF00180.20 CCH59965.1 - 3.2e-124 414.6 0.0 3.6e-124 414.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L30 PF00327.20 CCH59966.1 - 3.4e-11 42.9 0.3 3.4e-11 42.9 0.3 2.2 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e PDCD2_C PF04194.13 CCH59967.1 - 6.6e-40 137.0 3.0 1.1e-35 123.2 1.8 3.3 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zinc_ribbon_10 PF10058.9 CCH59967.1 - 0.00087 19.0 0.4 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein GTP_EFTU PF00009.27 CCH59968.1 - 1.2e-29 103.2 0.9 2.6e-29 102.1 0.9 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCH59968.1 - 2.1e-27 95.3 1.9 9.2e-27 93.2 1.9 2.2 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CCH59968.1 - 3.7e-08 33.4 1.3 3.7e-08 33.4 1.3 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCH59968.1 - 3.1e-07 30.0 1.0 3.1e-07 30.0 1.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CCH59968.1 - 6.4e-07 29.1 1.3 1.7e-06 27.7 0.2 2.2 2 1 0 2 2 2 1 Ras family Roc PF08477.13 CCH59968.1 - 8.9e-06 25.9 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCH59968.1 - 2.9e-05 23.6 1.0 2.9e-05 23.6 1.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 CCH59968.1 - 0.00065 19.6 1.6 0.59 10.1 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 CCH59968.1 - 0.00096 19.5 0.5 0.015 15.7 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Arf PF00025.21 CCH59968.1 - 0.001 18.5 0.4 0.0032 16.9 0.4 1.8 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.27 CCH59968.1 - 0.014 15.9 1.4 0.11 13.0 0.2 2.7 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CCH59968.1 - 0.015 15.3 1.3 0.69 9.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CCH59968.1 - 0.088 12.9 9.7 0.12 12.5 1.4 3.3 3 1 1 4 4 4 0 Dynamin family Androgen_recep PF02166.16 CCH59969.1 - 0.15 10.8 3.5 0.21 10.4 3.5 1.2 1 0 0 1 1 1 0 Androgen receptor Mito_fiss_reg PF05308.11 CCH59969.1 - 0.22 11.6 3.6 0.23 11.5 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CCH59969.1 - 1 8.8 7.1 1.2 8.6 7.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPP_enzyme_N PF02776.18 CCH59970.1 - 3e-27 95.3 0.0 5.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH59970.1 - 1.6e-22 79.7 0.0 3.3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH59970.1 - 1.2e-21 77.1 0.1 3.5e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pet191_N PF10203.9 CCH59971.1 - 2.1e-21 76.0 3.8 3e-21 75.5 3.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 CCH59971.1 - 0.021 14.8 0.6 3.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CCH59971.1 - 0.095 12.9 1.5 1.5 9.1 0.3 2.5 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 CCH59971.1 - 0.15 12.1 7.2 1.1 9.3 0.7 3.1 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Rav1p_C PF12234.8 CCH59972.1 - 1.8e-244 812.9 1.6 1.8e-244 812.9 1.6 2.3 2 1 0 2 2 2 2 RAVE protein 1 C terminal Pro_isomerase PF00160.21 CCH59973.1 - 1.1e-42 145.9 0.0 2.4e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 CCH59973.1 - 1.4e-08 34.2 14.6 2.7e-06 27.0 4.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCH59973.1 - 1.8e-08 33.8 8.6 0.00015 21.6 2.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH59973.1 - 4.3e-05 23.4 9.0 0.0013 18.7 1.5 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCH59973.1 - 0.0005 20.3 1.2 0.067 13.5 1.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCH59973.1 - 0.0007 20.2 0.0 0.0016 19.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCH59973.1 - 0.0096 16.5 2.1 0.063 13.9 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Phage_term_smal PF05944.12 CCH59973.1 - 0.012 15.6 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Phage small terminase subunit TPR_19 PF14559.6 CCH59973.1 - 0.021 15.3 0.1 0.091 13.3 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Peripla_BP_4 PF13407.6 CCH59973.1 - 0.048 13.2 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain TPR_11 PF13414.6 CCH59973.1 - 0.084 12.6 1.0 8.1 6.2 0.1 3.2 3 0 0 3 3 3 0 TPR repeat DUF357 PF04010.13 CCH59973.1 - 0.33 11.1 3.1 0.94 9.6 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF357) Sec7 PF01369.20 CCH59974.1 - 2.5e-64 216.3 3.4 2.5e-64 216.3 3.4 2.9 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CCH59974.1 - 1.6e-10 41.1 5.3 1.6e-10 41.1 5.3 3.8 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CCH59974.1 - 0.00024 20.8 0.4 0.00024 20.8 0.4 4.1 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF3970 PF13113.6 CCH59974.1 - 0.037 14.2 0.5 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) OMPdecase PF00215.24 CCH59975.1 - 4.7e-74 248.8 0.0 5.5e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2235 PF09994.9 CCH59976.1 - 1.3e-78 264.3 0.1 1.9e-78 263.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FSH1 PF03959.13 CCH59976.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HECT PF00632.25 CCH59977.1 - 8.1e-78 262.0 1.1 8.1e-78 262.0 1.1 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Voltage_CLC PF00654.20 CCH59978.1 - 3.9e-79 266.5 25.2 3.9e-79 266.5 25.2 1.3 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CCH59978.1 - 1.7e-13 50.8 0.0 3.2e-06 27.5 0.0 3.4 3 0 0 3 3 3 2 CBS domain DUF4536 PF15055.6 CCH59978.1 - 6.9 7.0 9.9 0.21 11.8 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) Urb2 PF10441.9 CCH59979.1 - 1e-26 94.2 2.9 1e-26 94.2 2.9 2.7 2 0 0 2 2 2 1 Urb2/Npa2 family Nucleopor_Nup85 PF07575.13 CCH59980.1 - 4.8e-180 599.9 15.3 5.7e-180 599.6 15.3 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin ATP-synt_C PF00137.21 CCH59981.1 - 1.5e-34 118.2 31.0 2.4e-22 79.0 12.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 CCH59981.1 - 2.1 8.2 9.9 0.87 9.5 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) EMC3_TMCO1 PF01956.16 CCH59982.1 - 0.12 12.1 3.3 0.22 11.2 3.3 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like CDC27 PF09507.10 CCH59982.1 - 0.68 9.3 42.8 1.2 8.5 0.0 2.7 2 1 0 2 2 2 0 DNA polymerase subunit Cdc27 DUF349 PF03993.12 CCH59982.1 - 0.71 10.2 10.4 1.9 8.8 10.4 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Phos_pyr_kin PF08543.12 CCH59983.1 - 5.8e-07 29.1 0.0 8.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCH59983.1 - 0.002 17.5 0.1 0.0049 16.2 0.0 1.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Vps55 PF04133.14 CCH59984.1 - 4.2e-41 139.6 5.6 4.9e-41 139.4 5.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 SdpI PF13630.6 CCH59984.1 - 0.8 9.9 5.7 0.96 9.6 0.2 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family CDT1 PF08839.11 CCH59985.1 - 0.0039 17.5 5.3 0.015 15.6 5.3 2.1 1 1 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 CCH59985.1 - 0.086 13.3 0.1 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain DUF1691 PF07950.11 CCH59986.1 - 1.8e-10 41.5 3.3 0.00027 21.6 0.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 CCH59986.1 - 0.079 13.0 12.0 0.34 10.9 0.1 2.4 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PHD PF00628.29 CCH59987.1 - 3.2e-10 39.8 7.5 3.2e-10 39.8 7.5 2.6 2 0 0 2 2 2 1 PHD-finger PB1-F2 PF11986.8 CCH59987.1 - 0.061 13.5 0.3 0.17 12.1 0.3 1.7 1 0 0 1 1 1 0 Influenza A Proapoptotic protein YqfQ PF14181.6 CCH59987.1 - 0.1 12.8 1.7 0.22 11.7 1.7 1.5 1 0 0 1 1 1 0 YqfQ-like protein WD40 PF00400.32 CCH59988.1 - 0.017 16.0 4.0 3.9 8.5 0.0 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CCH59988.1 - 0.044 14.0 0.0 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.25 CCH59989.1 - 1.7e-61 207.9 0.0 2.9e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH59989.1 - 2.7e-35 121.9 0.0 4.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH59989.1 - 1.2e-07 31.4 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCH59989.1 - 0.02 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CCH59989.1 - 0.024 14.3 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CCH59989.1 - 0.046 13.1 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.18 CCH59990.1 - 9.1e-60 202.4 4.4 1.2e-57 195.5 4.4 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.11 CCH59991.1 - 1.5e-97 327.6 60.8 1.7e-97 327.3 60.8 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ABC_membrane_2 PF06472.15 CCH59992.1 - 2.5e-73 246.8 13.2 5.1e-73 245.8 13.2 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCH59992.1 - 2.4e-11 44.3 0.0 9.6e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCH59992.1 - 0.027 13.9 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Methyltransf_12 PF08242.12 CCH59993.1 - 1.2e-15 58.0 1.1 2.3e-14 53.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH59993.1 - 1.5e-14 54.2 0.0 2.8e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH59993.1 - 6.1e-11 42.9 0.0 1.3e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH59993.1 - 2.8e-09 37.5 0.0 6.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH59993.1 - 5.8e-06 26.2 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH59993.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 CCH59993.1 - 0.1 13.6 0.0 0.19 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain APG5 PF04106.12 CCH59994.1 - 8.6e-41 140.0 1.3 1.1e-40 139.7 1.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 RRM_1 PF00076.22 CCH59995.1 - 0.021 14.6 0.1 0.05 13.4 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TraI_2_C PF07515.11 CCH59995.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term TruD PF01142.18 CCH59996.1 - 3.7e-77 259.9 2.8 1.6e-72 244.7 1.1 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) YhzD PF14120.6 CCH59996.1 - 0.13 12.4 0.6 0.7 10.0 0.1 2.4 2 0 0 2 2 2 0 YhzD-like protein WD40 PF00400.32 CCH59997.1 - 9.7e-34 114.9 16.6 3e-07 31.0 0.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CCH59997.1 - 0.018 13.8 0.6 12 4.4 0.0 4.0 2 1 3 5 5 5 0 Nup133 N terminal like MOZ_SAS PF01853.18 CCH59998.1 - 3e-82 274.6 0.7 4.2e-82 274.1 0.7 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 CCH59998.1 - 1.3e-21 76.2 0.1 2.8e-21 75.2 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 CCH59998.1 - 5.5e-21 73.9 0.5 1.6e-20 72.5 0.5 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCH59998.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCH59998.1 - 0.0028 17.9 0.0 0.0079 16.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PTPA PF03095.15 CCH59999.1 - 4.3e-112 374.5 1.1 4.9e-112 374.3 1.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.13 CCH60000.1 - 2.1e-74 250.1 4.1 1.2e-72 244.4 4.1 2.0 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Kinesin PF00225.23 CCH60001.1 - 1.9e-77 260.4 0.2 2.6e-77 260.0 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCH60001.1 - 5.9e-19 68.5 0.0 1.2e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PAX PF00292.18 CCH60001.1 - 0.027 14.4 0.0 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 'Paired box' domain MPS2 PF17060.5 CCH60001.1 - 0.062 12.6 1.7 0.13 11.5 1.7 1.5 1 0 0 1 1 1 0 Monopolar spindle protein 2 FAM76 PF16046.5 CCH60001.1 - 0.12 11.7 0.4 0.26 10.6 0.4 1.5 1 0 0 1 1 1 0 FAM76 protein DUF4763 PF15960.5 CCH60001.1 - 0.91 8.8 5.6 0.49 9.7 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Ndc1_Nup PF09531.10 CCH60002.1 - 2.9e-96 323.6 4.0 3.4e-96 323.3 4.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.15 CCH60003.1 - 3.1e-52 176.6 0.0 4.8e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MSC PF09402.10 CCH60004.1 - 2.3e-98 329.8 5.1 2.3e-98 329.8 5.1 3.6 3 1 1 4 4 4 1 Man1-Src1p-C-terminal domain Zn_clus PF00172.18 CCH60004.1 - 1.2e-07 31.7 11.5 1.2e-07 31.7 11.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HeH PF12949.7 CCH60004.1 - 1.5e-07 31.0 0.3 3.5e-07 29.8 0.3 1.6 1 0 0 1 1 1 1 HeH/LEM domain Orf78 PF06024.12 CCH60004.1 - 0.14 12.4 0.1 0.14 12.4 0.1 6.2 5 1 1 6 6 6 0 Orf78 (ac78) A_deaminase PF00962.22 CCH60005.1 - 1e-128 429.3 0.0 1.4e-128 428.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MAT1 PF06391.13 CCH60006.1 - 1.7e-61 207.6 30.3 2.1e-61 207.3 30.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CCH60006.1 - 2.3e-27 94.6 8.5 5e-27 93.5 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH60006.1 - 0.00023 20.9 4.3 0.00052 19.8 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH60006.1 - 0.00048 20.4 6.5 0.00082 19.7 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCH60006.1 - 0.0011 18.7 6.4 0.0024 17.7 6.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH60006.1 - 0.017 14.9 6.8 0.075 12.9 6.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH60006.1 - 0.04 13.9 6.7 0.089 12.8 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCH60006.1 - 0.11 12.5 9.4 1.4 9.0 9.6 2.3 1 1 1 2 2 2 0 zinc-RING finger domain TFR_dimer PF04253.15 CCH60006.1 - 0.23 11.6 4.9 0.68 10.0 4.9 1.8 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain zf-RING_4 PF14570.6 CCH60006.1 - 1.2 9.0 10.3 15 5.5 10.4 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CCH60006.1 - 2.5 8.0 9.7 7.4 6.5 3.7 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Ead_Ea22 PF13935.6 CCH60006.1 - 5.4 7.7 12.4 3.3 8.4 5.3 2.2 1 1 1 2 2 2 0 Ead/Ea22-like protein CGI-121 PF08617.10 CCH60007.1 - 1.8e-31 109.4 5.0 2.3e-31 109.1 5.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 BCDHK_Adom3 PF10436.9 CCH60007.1 - 0.026 14.4 0.1 0.037 13.9 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase PRIMA1 PF16101.5 CCH60008.1 - 0.54 10.3 12.6 1.2 9.2 12.6 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 CCH60008.1 - 7.2 6.6 15.5 0.066 13.3 6.9 1.9 2 1 1 3 3 3 0 Mitochondrial fission regulator MRP-L28 PF09812.9 CCH60009.1 - 4.6e-20 72.4 1.5 5.1e-20 72.2 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Cyclin_C PF02984.19 CCH60009.1 - 0.073 13.2 0.4 0.092 12.8 0.4 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain TPT PF03151.16 CCH60010.1 - 3.8e-15 56.0 18.9 6.7e-08 32.2 1.6 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 CCH60010.1 - 4.8e-07 29.3 2.0 0.00068 18.9 1.2 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 CCH60010.1 - 0.0022 18.2 28.7 0.014 15.6 6.3 3.3 3 0 0 3 3 3 2 EamA-like transporter family HKR_ArcB_TM PF18415.1 CCH60010.1 - 0.04 14.7 0.7 0.04 14.7 0.7 2.7 2 1 1 3 3 3 0 Histidine kinase receptor ArcB trans-membrane domain DUF2231 PF09990.9 CCH60010.1 - 0.047 14.1 0.7 0.16 12.4 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Ni_hydr_CYTB PF01292.20 CCH60010.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 zf-C2H2 PF00096.26 CCH60012.1 - 4.8e-10 39.3 7.5 6.9e-05 23.1 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH60012.1 - 2.5e-08 34.0 4.4 2.5e-08 34.0 4.4 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH60012.1 - 3.1e-05 24.4 5.4 0.018 15.8 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH60012.1 - 0.003 17.8 2.6 0.0098 16.2 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCH60012.1 - 0.0035 17.7 1.7 0.13 12.7 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCH60012.1 - 0.0074 16.3 4.5 0.032 14.2 0.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.11 CCH60012.1 - 0.019 14.9 2.6 0.019 14.9 2.6 1.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_3rep PF18868.1 CCH60012.1 - 0.032 14.9 1.1 0.073 13.7 0.7 1.8 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 CCH60012.1 - 0.12 10.9 1.4 0.16 10.4 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Zf_RING PF16744.5 CCH60012.1 - 0.17 12.0 0.9 0.48 10.6 0.9 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zf-BED PF02892.15 CCH60012.1 - 0.29 11.2 4.9 0.96 9.5 4.9 1.9 1 0 0 1 1 1 0 BED zinc finger zf_C2H2_ZHX PF18387.1 CCH60012.1 - 4.4 7.0 11.4 0.68 9.6 2.7 3.0 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Fas_alpha_ACP PF18325.1 CCH60013.1 - 4.1e-71 238.6 0.0 8.4e-71 237.5 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 CCH60013.1 - 3.9e-69 232.3 0.2 8.5e-69 231.3 0.2 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 CCH60013.1 - 2.9e-20 72.9 0.0 6.1e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CCH60013.1 - 9.3e-13 48.2 0.0 2.2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 CCH60013.1 - 4.2e-12 46.2 0.0 1.5e-11 44.5 0.0 2.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily KR PF08659.10 CCH60013.1 - 0.00031 20.7 0.0 0.00088 19.2 0.0 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCH60013.1 - 0.088 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein BASP1 PF05466.12 CCH60013.1 - 3.2 7.7 22.7 6.8 6.6 22.7 1.5 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) Syntaxin PF00804.25 CCH60014.1 - 6.1e-21 75.0 16.9 6.1e-21 75.0 16.9 2.9 2 1 1 3 3 3 1 Syntaxin SNARE PF05739.19 CCH60014.1 - 1.4e-13 50.6 2.0 4.1e-13 49.1 2.0 1.9 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 CCH60014.1 - 0.00045 19.9 3.1 0.00045 19.9 3.1 2.3 2 1 0 2 2 2 1 Synaptobrevin SLATT_5 PF18160.1 CCH60014.1 - 0.0029 16.9 0.1 0.0029 16.9 0.1 2.5 3 1 1 4 4 4 1 SMODS and SLOG-associating 2TM effector domain family 5 BLOC1_2 PF10046.9 CCH60014.1 - 0.0036 17.6 11.9 0.021 15.1 0.3 3.5 2 1 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5345 PF17280.2 CCH60014.1 - 0.0067 16.4 0.6 0.023 14.7 0.1 2.2 2 1 0 2 2 2 1 Family of unknown function (DUF5345) T2SSF PF00482.23 CCH60014.1 - 0.02 14.8 0.4 0.049 13.6 0.4 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F MMPL PF03176.15 CCH60014.1 - 0.037 13.0 1.6 0.054 12.4 1.6 1.3 1 0 0 1 1 1 0 MMPL family DUF745 PF05335.13 CCH60014.1 - 0.28 10.9 18.3 0.028 14.1 12.4 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) NIBRIN_BRCT_II PF16508.5 CCH60014.1 - 0.48 10.8 3.1 2.4 8.5 1.0 2.6 2 0 0 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein SlyX PF04102.12 CCH60014.1 - 2.9 8.6 15.1 0.3 11.7 6.6 2.7 2 1 0 2 2 2 0 SlyX zf-CpG_bind_C PF12269.8 CCH60014.1 - 3.1 7.5 10.3 0.55 10.0 1.2 2.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain PCRF PF03462.18 CCH60014.1 - 3.2 7.6 19.3 1 9.2 0.8 2.8 1 1 2 3 3 3 0 PCRF domain Jnk-SapK_ap_N PF09744.9 CCH60014.1 - 3.2 8.0 19.8 3.7 7.8 7.3 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 EAP30 PF04157.16 CCH60015.1 - 0.057 12.7 0.7 0.098 11.9 0.7 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family TFA2_Winged_2 PF18121.1 CCH60016.1 - 7.4e-22 76.8 0.1 2.2e-21 75.3 0.1 1.9 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CCH60016.1 - 9.9e-15 54.6 2.4 2.6e-14 53.2 2.4 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain RNA_pol_3_Rpc31 PF11705.8 CCH60016.1 - 0.011 16.0 15.7 0.011 16.0 15.7 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SMYLE_N PF18615.1 CCH60016.1 - 0.044 13.4 6.9 0.065 12.8 6.9 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4144 PF13642.6 CCH60016.1 - 0.075 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 protein structure with unknown function PPP4R2 PF09184.11 CCH60016.1 - 0.11 12.1 22.1 0.26 10.9 22.1 1.6 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 CCH60016.1 - 0.19 11.0 13.3 0.32 10.3 13.3 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CCH60016.1 - 0.79 10.1 12.7 1.7 9.1 12.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4746 PF15928.5 CCH60016.1 - 1.1 8.6 13.1 1.9 7.8 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Prothymosin PF03247.14 CCH60016.1 - 3.8 8.0 28.8 0.21 12.1 22.6 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pox_Ag35 PF03286.14 CCH60016.1 - 4.1 7.2 22.5 0.44 10.3 17.3 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GEMIN8 PF15348.6 CCH60016.1 - 4.8 7.4 12.4 9.5 6.4 12.4 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DDRGK PF09756.9 CCH60016.1 - 6.3 6.3 22.9 0.098 12.2 15.8 1.6 2 0 0 2 2 2 0 DDRGK domain Presenilin PF01080.17 CCH60016.1 - 6.9 5.3 15.3 9.7 4.8 15.3 1.1 1 0 0 1 1 1 0 Presenilin Las1 PF04031.13 CCH60017.1 - 7.7e-48 162.5 1.8 1.1e-47 162.0 0.3 2.0 2 0 0 2 2 2 1 Las1-like Zn_clus PF00172.18 CCH60018.1 - 1.4e-08 34.7 9.9 2.7e-08 33.8 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AdenylateSensor PF16579.5 CCH60018.1 - 0.12 12.8 1.3 11 6.5 0.1 2.6 2 0 0 2 2 2 0 Adenylate sensor of SNF1-like protein kinase NAD_binding_5 PF07994.12 CCH60019.1 - 7.1e-140 465.9 0.7 8.4e-140 465.7 0.7 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CCH60019.1 - 3.1e-45 152.9 1.6 3.6e-45 152.7 0.2 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Vps39_1 PF10366.9 CCH60020.1 - 1.2e-25 89.9 17.2 4.7e-25 88.0 3.9 4.3 3 0 0 3 3 3 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CCH60020.1 - 1.4e-10 41.6 0.6 4.9e-10 39.8 0.1 2.4 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CENP-B_dimeris PF09026.10 CCH60020.1 - 0.22 11.9 20.4 0.18 12.2 4.6 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CCH60020.1 - 1.2 8.7 3.6 10 5.8 0.3 2.5 2 0 0 2 2 2 0 FAM176 family WRNPLPNID PF15017.6 CCH60020.1 - 6.3 7.7 10.8 15 6.6 1.7 2.7 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Utp21 PF04192.12 CCH60021.1 - 1.4e-76 257.1 0.1 2.5e-76 256.3 0.1 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CCH60021.1 - 1.4e-19 70.2 0.0 5.2e-05 23.5 0.0 6.3 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH60021.1 - 7.4e-13 48.8 18.9 1.9e-06 28.5 0.4 8.4 9 0 0 9 9 9 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CCH60021.1 - 0.067 11.7 0.0 0.23 10.0 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 CCH60021.1 - 0.44 10.5 2.7 0.94 9.5 0.1 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat His_Phos_2 PF00328.22 CCH60022.1 - 4.5e-123 411.4 0.4 6.8e-123 410.8 0.4 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CCH60022.1 - 3.4e-38 129.7 0.1 1e-37 128.1 0.1 1.9 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CCH60022.1 - 2.6e-09 36.9 0.0 7.8e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF5405 PF17399.2 CCH60022.1 - 0.01 16.0 0.1 0.092 13.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) PAS_12 PF18095.1 CCH60022.1 - 0.023 14.4 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain ATP-grasp_3 PF02655.14 CCH60022.1 - 0.077 13.0 0.1 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 ATP-grasp domain Pribosyltran_N PF13793.6 CCH60023.1 - 1.5e-40 137.8 0.0 8.9e-40 135.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCH60023.1 - 2.2e-36 125.6 3.7 5.9e-29 101.4 0.3 2.2 1 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCH60023.1 - 2.9e-08 33.4 0.9 0.0012 18.4 0.1 2.5 2 1 0 2 2 2 2 Phosphoribosyl transferase domain SRR1 PF07985.12 CCH60024.1 - 1.1e-16 60.6 0.0 2.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 SRR1 Voldacs PF03517.13 CCH60025.1 - 8.4e-12 45.4 0.1 1.5e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DUF2960 PF11173.8 CCH60026.1 - 0.064 13.7 0.2 0.16 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) CIMR PF00878.18 CCH60027.1 - 4.2e-11 43.1 1.1 6e-05 23.1 0.2 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 CCH60027.1 - 9.6e-07 28.1 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 CCH60027.1 - 0.00018 21.3 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein GTP_EFTU PF00009.27 CCH60028.1 - 2.4e-54 183.8 0.0 3.4e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCH60028.1 - 5.9e-40 136.1 0.0 1.2e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCH60028.1 - 1.6e-13 50.9 1.2 1.6e-13 50.9 1.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH60028.1 - 0.0002 21.4 0.2 0.005 16.9 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Met_asp_mut_E PF06368.11 CCH60028.1 - 0.023 13.2 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) GTP_EFTU_D4 PF14578.6 CCH60028.1 - 0.082 12.8 2.1 0.1 12.5 0.5 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 RRM_1 PF00076.22 CCH60029.1 - 6.9e-11 41.8 0.7 1.1e-05 25.1 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tn7_Tnp_TnsA_C PF08721.11 CCH60029.1 - 0.0093 16.6 3.9 1 10.0 0.0 3.3 3 0 0 3 3 3 2 TnsA endonuclease C terminal DUF1874 PF08960.10 CCH60029.1 - 0.015 15.4 0.1 0.052 13.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) HGTP_anticodon PF03129.20 CCH60030.1 - 8.5e-22 77.1 2.2 9.8e-22 76.9 0.3 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCH60030.1 - 3.6e-07 30.3 0.1 4.3e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DIM1 PF02966.16 CCH60031.1 - 4.5e-67 223.9 1.1 5.2e-67 223.7 1.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CCH60031.1 - 0.0019 18.2 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin RP1-2 PF12042.8 CCH60033.1 - 0.39 10.6 6.0 0.66 9.8 6.0 1.3 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain ATP-synt_ab PF00006.25 CCH60034.1 - 2.5e-66 223.4 0.0 3.5e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCH60034.1 - 7e-15 55.3 0.8 1.4e-14 54.3 0.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CCH60034.1 - 0.024 13.6 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Atg14 PF10186.9 CCH60035.1 - 7.7e-13 48.2 19.6 7.7e-13 48.2 19.6 2.3 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 NOB1_Zn_bind PF08772.11 CCH60035.1 - 0.083 13.1 2.6 0.12 12.5 0.2 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Peptidase_C50 PF03568.17 CCH60037.1 - 9.6e-131 436.5 0.2 9.6e-131 436.5 0.2 1.9 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 CCH60037.1 - 0.024 14.1 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 CHAT domain HARE-HTH PF05066.13 CCH60037.1 - 0.025 15.0 0.5 5.8 7.4 0.0 3.1 3 0 0 3 3 3 0 HB1, ASXL, restriction endonuclease HTH domain Mito_carr PF00153.27 CCH60039.1 - 9.2e-58 192.2 2.0 3.1e-19 68.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3084 PF11283.8 CCH60039.1 - 0.25 11.4 2.1 0.95 9.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) tRNA-synt_1 PF00133.22 CCH60040.1 - 5e-209 695.5 0.3 6.7e-208 691.8 0.3 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCH60040.1 - 6e-27 94.5 5.3 1.3e-26 93.4 5.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCH60040.1 - 1.5e-16 60.1 4.3 8.3e-09 34.7 0.1 5.1 4 2 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCH60040.1 - 1.1e-11 44.6 0.1 1.3e-07 31.3 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CCH60040.1 - 0.0044 16.4 0.7 0.053 12.9 0.7 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 CCH60040.1 - 0.02 15.1 1.7 0.034 14.4 0.5 2.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm RRM_1 PF00076.22 CCH60041.1 - 1.3e-68 226.8 13.1 4.7e-18 64.8 0.1 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCH60041.1 - 6.8e-08 32.2 0.2 3.9e-05 23.2 0.1 3.8 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCH60041.1 - 1.3e-05 25.1 0.3 0.18 11.9 0.0 4.3 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCH60041.1 - 9.6e-05 22.4 0.3 5.5 7.2 0.0 4.7 4 0 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 CCH60041.1 - 0.00067 19.5 0.1 0.63 9.9 0.0 3.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4944 PF16302.5 CCH60041.1 - 0.0026 17.8 3.2 0.022 14.8 0.1 3.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4944) Limkain-b1 PF11608.8 CCH60041.1 - 0.025 14.6 1.1 15 5.7 0.0 4.0 3 1 0 3 3 3 0 Limkain b1 RNA_bind PF08675.11 CCH60041.1 - 0.069 13.2 0.3 10 6.2 0.0 3.9 5 0 0 5 5 5 0 RNA binding domain Pkinase PF00069.25 CCH60042.1 - 9.3e-57 192.4 0.0 4e-56 190.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60042.1 - 1.6e-27 96.5 0.1 3.3e-19 69.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CCH60042.1 - 7.9e-05 23.3 2.9 0.00045 20.9 2.4 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCH60042.1 - 0.0011 17.9 1.5 0.0039 16.2 1.5 1.8 1 1 0 1 1 1 1 Haspin like kinase domain CAP_assoc_N PF14504.6 CCH60042.1 - 0.0026 17.5 0.6 0.51 10.1 0.0 2.4 1 1 1 2 2 2 2 CAP-associated N-terminal Kdo PF06293.14 CCH60042.1 - 0.0031 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCH60042.1 - 0.0067 15.8 0.0 0.073 12.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCH60042.1 - 0.15 12.0 0.1 0.59 10.0 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.18 CCH60043.1 - 3e-63 213.4 1.7 3e-63 213.4 1.7 1.7 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CCH60043.1 - 7.1e-27 94.7 3.3 7.1e-27 94.7 3.3 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain GldM_C PF12080.8 CCH60043.1 - 0.021 15.1 0.2 0.037 14.2 0.2 1.4 1 0 0 1 1 1 0 GldM C-terminal domain ExsD PF16806.5 CCH60043.1 - 0.61 10.0 11.2 0.12 12.3 4.4 2.6 3 0 0 3 3 3 0 Antiactivator protein ExsD Jnk-SapK_ap_N PF09744.9 CCH60043.1 - 1.5 9.0 11.4 0.21 11.8 1.4 3.2 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DUF1746 PF08508.10 CCH60044.1 - 1.4e-08 35.1 0.2 0.00065 20.0 0.0 2.7 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1746) RPN7 PF10602.9 CCH60046.1 - 2.5e-52 177.1 3.6 4.6e-52 176.2 3.6 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CCH60046.1 - 1.4e-16 60.9 0.1 1.4e-16 60.9 0.1 2.2 2 1 0 2 2 2 1 PCI domain HTH_11 PF08279.12 CCH60046.1 - 0.015 15.2 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 HTH domain BBS1 PF14779.6 CCH60046.1 - 0.017 14.6 0.4 0.032 13.7 0.4 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Interferon PF00143.19 CCH60046.1 - 0.11 12.7 2.8 0.24 11.6 2.8 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain zf-CCCH PF00642.24 CCH60047.1 - 1.2e-19 69.8 36.1 1.2e-05 25.1 1.0 5.9 6 0 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCH60047.1 - 8.9e-18 63.7 37.1 2.2e-06 27.5 3.4 6.0 5 1 0 5 5 5 5 Zinc finger domain Torus PF16131.5 CCH60047.1 - 2.8e-10 40.9 28.1 0.00038 21.1 0.8 5.2 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 CCH60047.1 - 4.7e-09 36.4 16.9 1.1e-07 32.0 7.2 2.7 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CCH60047.1 - 1e-06 28.4 32.6 1.3e-06 28.1 0.6 5.2 5 1 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCH60047.1 - 0.0032 17.9 40.1 0.39 11.3 2.5 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Defensin_int PF17858.1 CCH60047.1 - 1.6 8.7 25.2 2.1 8.4 0.4 4.7 5 0 0 5 5 5 0 Platypus intermediate defensin-like peptide YgbA_NO PF11756.8 CCH60047.1 - 4.5 7.7 7.9 1.6 9.1 4.0 2.2 1 1 1 2 2 2 0 Nitrous oxide-stimulated promoter Pil1 PF13805.6 CCH60048.1 - 7.1e-117 389.6 0.0 8.8e-117 389.3 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Forkhead PF00250.18 CCH60049.1 - 2.6e-24 85.3 0.1 7.7e-24 83.8 0.1 1.8 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CCH60049.1 - 6.3e-14 52.1 0.4 1.7e-13 50.7 0.4 1.9 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CCH60049.1 - 0.016 15.4 0.5 0.14 12.4 0.0 2.8 3 0 0 3 3 3 0 FHA domain Linker_histone PF00538.19 CCH60049.1 - 0.12 12.7 0.0 0.12 12.7 0.0 3.1 4 0 0 4 4 4 0 linker histone H1 and H5 family Ribosomal_L5_C PF00673.21 CCH60050.1 - 1.4e-21 76.4 0.0 2.3e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCH60050.1 - 5.1e-20 71.6 0.1 1.1e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CCH60050.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain BCAS2 PF05700.11 CCH60051.1 - 4.4e-05 23.3 10.9 0.00067 19.4 10.9 2.3 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Prefoldin_3 PF13758.6 CCH60051.1 - 2.5 8.2 6.7 0.27 11.3 0.5 2.4 3 0 0 3 3 3 0 Prefoldin subunit IF-2B PF01008.17 CCH60053.1 - 3e-104 348.2 0.4 3e-104 348.2 0.4 1.8 2 0 0 2 2 2 1 Initiation factor 2 subunit family Dsh_C PF12316.8 CCH60053.1 - 3.4 8.0 9.9 16 5.8 6.6 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal MAS20 PF02064.15 CCH60054.1 - 9.7e-37 125.9 0.5 1.2e-36 125.7 0.5 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor FIST_C PF10442.9 CCH60054.1 - 0.0023 17.9 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 FIST C domain SLX9 PF15341.6 CCH60055.1 - 8.4e-20 71.5 17.8 8.4e-20 71.5 17.8 2.0 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 MtaB PF12176.8 CCH60055.1 - 0.027 13.3 0.6 0.042 12.6 0.1 1.6 1 1 1 2 2 2 0 Methanol-cobalamin methyltransferase B subunit AKAP95 PF04988.12 CCH60055.1 - 0.15 12.2 4.9 0.19 12.0 0.7 2.4 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) STG PF15809.5 CCH60055.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 2 0 Simian taste bud-specific gene product family Tweety PF04906.13 CCH60055.1 - 0.25 9.9 1.3 0.34 9.5 1.3 1.2 1 0 0 1 1 1 0 Tweety CorA PF01544.18 CCH60055.1 - 0.28 10.5 6.0 0.41 9.9 6.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3818 PF12825.7 CCH60056.1 - 2.8e-116 388.2 24.6 2.8e-116 388.2 24.6 3.8 4 0 0 4 4 4 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CCH60056.1 - 2.6e-31 108.3 3.9 2.6e-31 108.3 3.9 3.5 4 0 0 4 4 4 1 PX-associated PX PF00787.24 CCH60056.1 - 4.2e-10 39.6 5.6 4.2e-10 39.6 5.6 3.1 3 1 0 3 3 3 1 PX domain 30K_MP_core PF17644.1 CCH60056.1 - 0.029 14.3 1.0 0.075 12.9 1.0 1.6 1 0 0 1 1 1 0 Core domain of 30K viral movement proteins Sec7 PF01369.20 CCH60057.1 - 2.2e-28 99.2 0.7 2.2e-28 99.2 0.7 2.6 2 0 0 2 2 2 1 Sec7 domain Nre_C PF04895.12 CCH60057.1 - 0.16 11.9 0.4 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Archaeal Nre, C-terminal PH PF00169.29 CCH60057.1 - 0.22 12.1 2.5 20 5.8 2.5 3.3 1 1 0 1 1 1 0 PH domain KdpD PF02702.17 CCH60058.1 - 0.2 11.1 0.7 0.4 10.1 0.7 1.5 1 1 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain DUF573 PF04504.14 CCH60058.1 - 0.35 11.6 2.6 1.8 9.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF573 CKS PF01111.19 CCH60059.1 - 5.2e-33 113.1 0.1 8.1e-33 112.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SUIM_assoc PF16619.5 CCH60059.1 - 0.0002 21.3 8.9 0.0059 16.7 8.9 2.2 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Presenilin PF01080.17 CCH60059.1 - 0.18 10.6 0.9 0.17 10.6 0.9 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 CCH60059.1 - 0.59 10.1 7.9 0.72 9.8 7.3 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 CCH60059.1 - 4.7 8.2 7.4 7.6 7.6 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PRMT5_TIM PF17285.2 CCH60060.1 - 8.3e-64 215.2 10.8 8.3e-64 215.2 10.8 2.3 2 0 0 2 2 2 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CCH60060.1 - 9.6e-54 181.9 5.8 1.8e-53 181.0 5.8 1.5 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 CCH60060.1 - 2.9e-48 164.0 2.7 4.8e-48 163.3 0.1 2.7 3 0 0 3 3 3 1 PRMT5 arginine-N-methyltransferase DIL PF01843.19 CCH60061.1 - 2.2e-11 44.0 9.0 5.2e-10 39.5 9.0 2.7 1 1 0 1 1 1 1 DIL domain Mucin PF01456.17 CCH60061.1 - 2 8.4 7.0 0.6 10.1 0.5 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein AA_permease PF00324.21 CCH60062.1 - 3.3e-128 428.3 38.0 3.8e-128 428.1 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH60062.1 - 2.1e-24 86.1 38.5 2.6e-24 85.8 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1712 PF08217.11 CCH60063.1 - 5.9e-100 335.5 69.7 7.1e-90 302.2 18.3 3.0 1 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) End3 PF12761.7 CCH60063.1 - 0.012 15.8 1.8 0.012 15.8 1.8 3.5 3 1 1 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 TFIIB PF00382.19 CCH60064.1 - 6.6e-42 141.4 2.1 1.3e-26 92.4 1.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CCH60064.1 - 1.8e-13 49.8 0.5 3.3e-13 48.9 0.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CCH60064.1 - 0.12 11.9 0.5 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF1456 PF07308.13 CCH60064.1 - 0.18 12.1 0.4 0.59 10.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) Fmp27_WPPW PF10359.9 CCH60065.1 - 1.6e-132 442.8 11.2 1.6e-132 442.8 11.2 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CCH60065.1 - 1.4e-99 334.2 5.2 1.4e-99 334.2 5.2 3.3 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CCH60065.1 - 1.7e-47 161.4 0.2 4.8e-47 160.0 0.1 1.9 2 0 0 2 2 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCH60065.1 - 1.6e-39 135.3 4.4 2.4e-39 134.7 2.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCH60065.1 - 4.6e-19 69.0 2.6 1e-18 67.9 0.1 3.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain HOOK PF05622.12 CCH60065.1 - 0.00081 17.7 6.5 0.0018 16.5 6.5 1.5 1 0 0 1 1 1 1 HOOK protein CENP-H PF05837.12 CCH60065.1 - 0.0061 17.0 3.9 0.022 15.2 3.9 1.9 1 0 0 1 1 1 1 Centromere protein H (CENP-H) FlxA PF14282.6 CCH60065.1 - 0.033 14.2 3.6 0.14 12.2 3.6 2.1 1 0 0 1 1 1 0 FlxA-like protein Noelin-1 PF12308.8 CCH60065.1 - 0.036 14.0 0.1 0.13 12.3 0.1 2.0 1 0 0 1 1 1 0 Neurogenesis glycoprotein ABC_tran_CTD PF16326.5 CCH60065.1 - 0.12 12.6 3.1 0.35 11.1 3.1 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain HIP1_clath_bdg PF16515.5 CCH60065.1 - 0.16 12.6 3.3 0.65 10.6 3.3 2.1 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF948 PF06103.11 CCH60065.1 - 0.22 11.8 2.8 0.62 10.4 0.3 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Jnk-SapK_ap_N PF09744.9 CCH60065.1 - 0.34 11.1 5.8 1.5 9.0 5.8 2.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Rx_N PF18052.1 CCH60065.1 - 1.2 9.5 6.3 6.2 7.2 1.7 3.2 3 0 0 3 3 3 0 Rx N-terminal domain ZapB PF06005.12 CCH60065.1 - 1.6 9.2 7.6 2.3 8.7 5.9 2.2 2 0 0 2 2 1 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 CCH60065.1 - 2.5 8.6 9.1 2.6 8.5 5.8 2.8 2 0 0 2 2 2 0 Snapin/Pallidin NESP55 PF06390.12 CCH60065.1 - 2.8 7.5 9.7 5.5 6.5 9.7 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) CK2S PF15011.6 CCH60065.1 - 3.2 7.6 5.7 0.72 9.7 0.9 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate Med18 PF09637.10 CCH60067.1 - 5.7e-52 177.0 2.0 1.1e-49 169.5 2.0 2.1 1 1 0 1 1 1 1 Med18 protein VMA21 PF09446.10 CCH60068.1 - 4e-11 42.8 17.0 4e-10 39.7 17.0 1.9 1 1 0 1 1 1 1 VMA21-like domain SecY PF00344.20 CCH60069.1 - 1.1e-39 136.5 22.8 2e-39 135.7 22.8 1.4 1 1 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCH60069.1 - 0.00039 20.2 0.5 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p Ninjurin PF04923.12 CCH60069.1 - 0.28 11.1 10.2 0.061 13.3 2.0 2.9 2 1 0 2 2 2 0 Ninjurin MRP-L27 PF09809.9 CCH60070.1 - 3.9e-31 107.2 1.2 6e-31 106.6 0.9 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 Peptidase_M20 PF01546.28 CCH60071.1 - 3.5e-23 82.4 0.0 7.6e-23 81.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCH60071.1 - 4e-10 39.6 0.0 8.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CCH60071.1 - 5.6e-07 30.2 8.4 1.3 10.0 0.0 6.1 5 2 0 5 5 5 2 WD domain, G-beta repeat Peptidase_M42 PF05343.14 CCH60071.1 - 0.0023 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase ANAPC4_WD40 PF12894.7 CCH60071.1 - 0.003 17.8 0.1 13 6.2 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCH60071.1 - 0.0083 14.8 0.2 0.36 9.4 0.1 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CCH60071.1 - 0.087 11.7 0.2 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain RCC1_2 PF13540.6 CCH60072.1 - 1.7e-17 62.7 9.0 1.6e-07 31.0 0.6 4.7 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CCH60072.1 - 1.4e-16 60.8 1.3 5.2e-06 27.0 0.3 5.9 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Elongin_A PF06881.11 CCH60072.1 - 0.0018 18.8 0.3 0.087 13.4 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 CCH60072.1 - 0.0025 17.7 0.0 0.0049 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like Paf1 PF03985.13 CCH60073.1 - 1.3e-93 314.4 9.3 1.4e-93 314.2 9.3 1.0 1 0 0 1 1 1 1 Paf1 MPM1 PF17234.2 CCH60074.1 - 1.8e-39 135.7 10.4 2.7e-38 131.9 10.4 2.3 1 1 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 Cyclin_N PF00134.23 CCH60075.1 - 2.7e-37 127.3 0.2 3.5e-34 117.3 0.4 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCH60075.1 - 1.2e-26 93.1 0.0 2.8e-26 92.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4154 PF13689.6 CCH60075.1 - 0.019 15.2 0.5 0.23 11.7 0.1 2.4 1 1 1 2 2 2 0 YfiR/HmsC-like Cyclin_N PF00134.23 CCH60076.1 - 6.2e-40 135.9 4.6 2.9e-39 133.7 2.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCH60076.1 - 1.2e-15 57.7 0.5 1.2e-15 57.7 0.5 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain A_deaminase PF00962.22 CCH60077.1 - 7.6e-28 97.8 0.0 1.1e-14 54.5 0.0 3.7 3 1 0 3 3 3 2 Adenosine/AMP deaminase Penicillinase_R PF03965.16 CCH60077.1 - 0.11 12.8 0.1 1.7 9.0 0.0 2.7 3 0 0 3 3 3 0 Penicillinase repressor Bac_export_1 PF01311.20 CCH60077.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 1 Folliculin PF11704.8 CCH60077.1 - 0.46 10.3 3.3 0.22 11.4 0.5 1.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport NAT PF04768.13 CCH60078.1 - 3.9e-46 156.8 0.8 1.6e-45 154.8 0.5 2.1 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Peptidase_M28 PF04389.17 CCH60079.1 - 3.3e-38 131.4 0.0 5.6e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCH60079.1 - 4.9e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CCH60079.1 - 0.0039 16.9 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ PF00226.31 CCH60080.1 - 7.1e-20 70.9 4.9 7.1e-20 70.9 4.9 2.7 2 0 0 2 2 2 1 DnaJ domain Vut_1 PF02592.15 CCH60080.1 - 0.042 14.2 1.0 0.083 13.2 1.0 1.4 1 0 0 1 1 1 0 Putative vitamin uptake transporter TPR_6 PF13174.6 CCH60080.1 - 0.046 14.4 1.0 4.3 8.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5327 PF17261.2 CCH60080.1 - 5.5 7.8 15.4 0.15 12.8 7.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Mem_trans PF03547.18 CCH60081.1 - 1.8e-63 214.3 6.1 2.3e-63 213.9 6.1 1.1 1 0 0 1 1 1 1 Membrane transport protein Casein PF00363.18 CCH60081.1 - 0.053 13.9 2.6 0.13 12.7 2.6 1.6 1 0 0 1 1 1 0 Casein FixS PF03597.15 CCH60081.1 - 0.4 10.4 6.3 7.1 6.4 0.3 3.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type SMC_hinge PF06470.13 CCH60082.1 - 4.7e-32 110.7 0.3 1.9e-31 108.8 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 CCH60082.1 - 2.3e-12 46.8 91.4 1.7e-10 40.7 91.4 4.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCH60082.1 - 5.9e-11 42.7 5.8 5.9e-11 42.7 5.8 4.0 2 2 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system HsbA PF12296.8 CCH60082.1 - 0.0019 18.6 7.2 0.21 12.0 0.2 4.8 4 0 0 4 4 4 1 Hydrophobic surface binding protein A TMF_TATA_bd PF12325.8 CCH60082.1 - 0.0089 16.2 7.0 0.0089 16.2 7.0 8.7 2 2 7 10 10 10 1 TATA element modulatory factor 1 TATA binding TrmB PF01978.19 CCH60082.1 - 0.0096 15.8 0.3 0.051 13.5 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TPR_MLP1_2 PF07926.12 CCH60082.1 - 0.01 15.9 10.5 0.01 15.9 10.5 7.8 3 2 6 9 9 9 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 CCH60082.1 - 0.018 15.3 2.8 0.018 15.3 2.8 8.8 3 2 6 9 9 9 0 Domain of unknown function (DUF5082) CAP PF00188.26 CCH60083.1 - 5.8e-17 62.7 1.6 1.4e-16 61.5 1.6 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_1 PF00013.29 CCH60084.1 - 1.3e-72 239.6 33.7 4.9e-12 45.5 0.2 12.0 13 0 0 13 13 13 7 KH domain KH_2 PF07650.17 CCH60084.1 - 6.4e-11 41.9 5.8 0.00062 19.5 0.1 6.0 5 0 0 5 5 5 3 KH domain KH_5 PF13184.6 CCH60084.1 - 0.001 19.1 17.8 0.68 10.1 0.1 6.9 7 0 0 7 7 7 3 NusA-like KH domain HSP20 PF00011.21 CCH60084.1 - 0.011 15.9 3.3 5.8 7.1 0.2 4.2 3 1 1 4 4 4 0 Hsp20/alpha crystallin family KH_4 PF13083.6 CCH60084.1 - 0.011 15.6 2.6 4.2 7.3 0.0 4.8 5 0 0 5 5 5 0 KH domain DUF4597 PF15366.6 CCH60084.1 - 0.05 13.4 0.1 0.2 11.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4597) HTH_19 PF12844.7 CCH60084.1 - 0.31 11.1 1.9 14 5.8 0.0 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain Ras PF00071.22 CCH60085.1 - 3.4e-57 192.6 1.2 4e-57 192.3 1.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH60085.1 - 3.7e-36 124.0 0.7 6e-36 123.3 0.1 1.6 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH60085.1 - 2.2e-16 59.8 0.5 2.9e-16 59.4 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH60085.1 - 3.1e-07 30.0 0.3 3.8e-07 29.7 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH60085.1 - 5.1e-07 29.8 0.1 9e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH60085.1 - 2.7e-06 27.1 0.1 5.1e-06 26.2 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCH60085.1 - 3e-06 27.2 2.1 0.045 13.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCH60085.1 - 0.0072 16.7 0.0 0.013 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 CCH60085.1 - 0.02 14.3 0.1 0.051 13.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Mitofilin PF09731.9 CCH60086.1 - 1.8e-25 89.9 22.4 1.3e-15 57.3 0.0 3.0 2 1 1 3 3 3 2 Mitochondrial inner membrane protein Tubulin_3 PF14881.6 CCH60086.1 - 0.071 12.8 1.3 0.14 11.9 0.6 1.8 2 0 0 2 2 2 0 Tubulin domain SecA_SW PF07516.13 CCH60086.1 - 0.23 11.5 6.5 0.18 11.8 4.5 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain RhoGEF67_u2 PF16614.5 CCH60086.1 - 6.9 6.8 7.6 6.4 6.9 0.1 3.1 3 1 0 3 3 3 0 Unstructured region two on RhoGEF 6 and 7 DUF4065 PF13274.6 CCH60086.1 - 8.6 7.3 9.0 27 5.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4065) IBR PF01485.21 CCH60087.1 - 2.1e-18 66.3 50.1 1.2e-10 41.4 11.9 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CCH60087.1 - 8.9e-06 25.5 13.8 8.9e-06 25.5 13.8 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH60087.1 - 0.00017 21.3 6.5 0.00017 21.3 6.5 4.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH60087.1 - 0.00076 19.8 10.5 0.00076 19.8 10.5 4.6 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCH60087.1 - 0.0022 17.8 9.0 0.0022 17.8 9.0 5.0 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH60087.1 - 0.0028 17.6 8.3 0.0028 17.6 8.3 3.6 3 0 0 3 3 3 1 RING-type zinc-finger DUF3808 PF10300.9 CCH60088.1 - 2.1e-162 541.2 0.7 3.1e-162 540.6 0.7 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CCH60088.1 - 0.0014 18.7 1.7 0.059 13.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat SGT1 PF07093.11 CCH60088.1 - 0.078 11.4 2.6 0.96 7.8 0.2 2.1 2 0 0 2 2 2 0 SGT1 protein TBCC PF07986.12 CCH60089.1 - 0.089 12.5 0.3 0.21 11.3 0.1 1.6 1 1 1 2 2 2 0 Tubulin binding cofactor C EF-hand_4 PF12763.7 CCH60090.1 - 0.0017 18.3 0.1 0.0017 18.3 0.1 3.1 5 0 0 5 5 5 1 Cytoskeletal-regulatory complex EF hand Arrestin_C PF02752.22 CCH60091.1 - 7.5e-14 52.3 0.9 7.5e-14 52.3 0.9 4.9 6 0 0 6 6 6 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCH60091.1 - 2.4e-07 30.9 0.2 9.8e-06 25.7 0.4 3.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.15 CCH60092.1 - 1.8e-83 280.7 9.0 2.9e-83 280.0 4.4 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit AF0941-like PF14591.6 CCH60092.1 - 0.0096 16.5 2.0 0.2 12.2 0.2 3.0 2 0 0 2 2 2 1 AF0941-like SAS4 PF15460.6 CCH60092.1 - 0.011 15.7 0.3 0.047 13.8 0.3 2.1 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 mCpol PF18182.1 CCH60092.1 - 0.64 10.4 3.9 0.64 10.4 0.7 2.7 3 0 0 3 3 3 0 minimal CRISPR polymerase domain RNA_lig_T4_1 PF09511.10 CCH60093.1 - 2.1e-80 269.7 0.3 3.7e-80 268.9 0.3 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 CCH60093.1 - 8.9e-69 230.9 0.1 3.3e-68 229.0 0.0 2.0 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 CCH60093.1 - 1.5e-60 204.8 1.0 2.1e-60 204.3 1.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain DUF5496 PF17600.2 CCH60093.1 - 0.081 13.0 0.1 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5496) NTR2 PF15458.6 CCH60094.1 - 5e-31 108.4 18.3 5.6e-31 108.2 18.3 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 PRANC PF09372.10 CCH60094.1 - 0.64 10.4 5.4 10 6.6 0.5 2.6 2 0 0 2 2 2 0 PRANC domain GWT1 PF06423.12 CCH60095.1 - 3.9e-38 130.9 3.6 3.9e-38 130.9 3.6 2.7 2 1 0 2 2 2 1 GWT1 Ion_trans_2 PF07885.16 CCH60096.1 - 7e-25 86.8 32.8 1.5e-16 60.1 12.5 3.9 5 0 0 5 5 5 2 Ion channel Ion_trans PF00520.31 CCH60096.1 - 0.032 13.5 30.6 0.04 13.1 4.8 2.9 3 0 0 3 3 3 0 Ion transport protein Lig_chan PF00060.26 CCH60096.1 - 0.69 9.7 13.5 5.2 6.9 0.0 4.2 3 1 0 3 3 3 0 Ligand-gated ion channel Na_H_Exchanger PF00999.21 CCH60097.1 - 7.2e-56 189.6 32.6 1.1e-55 189.1 32.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.25 CCH60098.1 - 2.5e-66 223.8 0.0 4.9e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60098.1 - 3.6e-45 154.3 0.0 7.4e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH60098.1 - 2.9e-10 39.9 0.0 1.5e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCH60098.1 - 0.012 14.4 0.0 0.012 14.4 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase PTPLA PF04387.14 CCH60099.1 - 5.3e-51 172.6 8.0 6.7e-51 172.3 8.0 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.15 CCH60100.1 - 3.4e-169 563.7 18.6 3.4e-169 563.7 18.6 4.2 3 1 0 4 4 4 1 SIT4 phosphatase-associated protein ChAPs PF09295.10 CCH60101.1 - 8.2e-39 133.7 10.2 3e-29 102.2 6.2 2.6 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 CCH60101.1 - 0.05 13.8 0.2 0.53 10.5 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Arg_repressor PF01316.21 CCH60102.1 - 0.063 13.0 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Baculo_p24 PF05073.12 CCH60102.1 - 0.67 9.7 8.0 0.59 9.9 0.5 3.2 2 0 0 2 2 2 0 Baculovirus P24 capsid protein DUF866 PF05907.13 CCH60103.1 - 0.17 11.8 1.6 0.14 12.1 0.3 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) RabGAP-TBC PF00566.18 CCH60104.1 - 1.2e-10 41.4 10.6 1.2e-10 41.4 10.6 2.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain His_Phos_1 PF00300.22 CCH60105.1 - 6.1e-36 123.9 0.0 1e-27 97.1 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DBR1 PF05011.13 CCH60106.1 - 2.8e-12 47.3 0.2 8.4e-12 45.7 0.2 1.9 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos_2 PF12850.7 CCH60106.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Aa_trans PF01490.18 CCH60107.1 - 1.9e-89 300.2 34.3 2.2e-89 300.0 34.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2207 PF09972.9 CCH60107.1 - 1.2 7.8 0.0 1.2 7.8 0.0 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) AAA PF00004.29 CCH60108.1 - 2.6e-40 137.9 0.0 6.4e-40 136.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH60108.1 - 4.3e-06 26.4 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CCH60108.1 - 6.1e-05 23.0 0.0 0.00021 21.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCH60108.1 - 6.1e-05 23.3 0.0 0.0029 17.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CCH60108.1 - 0.00022 21.6 0.1 0.0041 17.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CCH60108.1 - 0.00039 20.6 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CCH60108.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CCH60108.1 - 0.0045 17.5 0.3 0.08 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CCH60108.1 - 0.0049 16.6 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCH60108.1 - 0.012 15.8 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCH60108.1 - 0.024 15.0 0.0 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 CCH60108.1 - 0.024 14.8 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCH60108.1 - 0.026 14.2 0.1 0.09 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCH60108.1 - 0.04 13.4 0.0 0.092 12.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CCH60108.1 - 0.041 13.8 0.0 5.7 6.8 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 CCH60108.1 - 0.048 13.1 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCH60108.1 - 0.051 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CCH60108.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CCH60108.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CCH60108.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_pol_Rbc25 PF08292.12 CCH60109.1 - 2.2e-49 167.0 0.3 2.8e-49 166.6 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CCH60109.1 - 5.2e-21 74.8 0.0 7.8e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CCH60109.1 - 0.0022 18.3 0.0 0.0048 17.2 0.0 1.6 1 1 0 1 1 1 1 S1 RNA binding domain LTV PF04180.14 CCH60110.1 - 6e-109 365.3 31.4 7.2e-109 365.0 31.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.11 CCH60111.1 - 3.1e-88 295.1 3.5 3.8e-88 294.8 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DivIC PF04977.15 CCH60111.1 - 0.033 14.0 5.9 0.13 12.1 0.3 3.1 3 0 0 3 3 3 0 Septum formation initiator DUF2252 PF10009.9 CCH60111.1 - 0.046 12.8 0.5 0.071 12.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) MbeD_MobD PF04899.12 CCH60111.1 - 0.64 10.2 4.9 1 9.5 0.8 2.9 4 0 0 4 4 4 0 MbeD/MobD like Osmo_CC PF08946.10 CCH60111.1 - 2.1 8.7 5.9 1.5 9.2 0.8 2.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF16 PF01519.16 CCH60111.1 - 2.9 8.4 8.7 2 8.9 5.9 2.1 2 1 0 2 2 2 0 Protein of unknown function DUF16 Ribosomal_L29 PF00831.23 CCH60111.1 - 5.2 7.1 6.7 8.1 6.5 0.1 2.9 3 0 0 3 3 3 0 Ribosomal L29 protein PUF PF00806.19 CCH60112.1 - 4e-34 114.4 5.3 0.00016 21.2 0.0 8.6 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat OSCP PF00213.18 CCH60112.1 - 0.014 15.5 0.2 0.91 9.6 0.0 2.9 1 1 2 3 3 3 0 ATP synthase delta (OSCP) subunit FANCI_S2 PF14676.6 CCH60112.1 - 0.12 12.7 0.7 2 8.7 0.1 2.6 2 0 0 2 2 2 0 FANCI solenoid 2 Cpn60_TCP1 PF00118.24 CCH60113.1 - 2.7e-151 504.6 9.4 3.1e-151 504.4 9.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 CCH60113.1 - 0.0094 16.3 0.1 0.11 12.8 0.0 2.7 3 0 0 3 3 3 1 Dinitrogenase iron-molybdenum cofactor DUF1357 PF07094.11 CCH60113.1 - 0.15 12.1 0.7 0.26 11.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) MFS_1 PF07690.16 CCH60114.1 - 2e-33 115.8 23.9 1.1e-32 113.3 22.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S13 PF00416.22 CCH60115.1 - 0.82 10.1 3.1 0.48 10.8 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S13/S18 COX5A PF02284.16 CCH60116.1 - 2.5e-38 130.2 0.5 3.6e-38 129.7 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF1266 PF06889.11 CCH60116.1 - 0.11 12.5 0.3 0.21 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) PIF1 PF05970.14 CCH60117.1 - 6.2e-55 186.8 4.7 8.9e-53 179.7 4.7 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CCH60117.1 - 4e-20 72.4 0.0 6.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH60117.1 - 8.2e-10 39.2 0.0 1.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCH60117.1 - 0.00013 22.3 0.3 0.0017 18.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain SH3_13 PF18335.1 CCH60117.1 - 0.0016 18.2 0.0 0.0046 16.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain T2SSE PF00437.20 CCH60117.1 - 0.0024 17.0 0.3 0.0052 15.9 0.3 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_7 PF12775.7 CCH60117.1 - 0.0033 17.0 2.3 0.0037 16.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region PhoH PF02562.16 CCH60117.1 - 0.018 14.5 0.1 0.058 12.8 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein UvrD_C_2 PF13538.6 CCH60117.1 - 0.036 13.9 0.4 0.2 11.5 0.4 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 CCH60117.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CCH60117.1 - 0.059 13.9 0.3 0.42 11.1 0.1 2.5 2 0 0 2 2 2 0 ABC transporter DUF2075 PF09848.9 CCH60117.1 - 0.075 12.3 0.2 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 CCH60117.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 CCH60117.1 - 0.085 12.9 0.0 0.44 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CCH60117.1 - 0.096 13.1 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 CCH60118.1 - 5.1e-59 199.8 0.0 7.4e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60118.1 - 1.7e-26 93.1 0.0 2.6e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH60118.1 - 7.1e-05 21.9 0.3 0.00012 21.2 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCH60118.1 - 0.021 14.2 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPN1_RPN2_N PF17781.1 CCH60119.1 - 3.4e-113 378.1 1.7 4.6e-113 377.7 0.8 1.7 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CCH60119.1 - 4.6e-29 100.2 0.1 8.5e-29 99.4 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CCH60119.1 - 7.4e-24 82.9 15.1 7.5e-08 32.4 0.1 7.7 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCH60119.1 - 6.6e-05 23.2 0.6 1 9.8 0.0 3.8 3 1 0 3 3 3 2 HEAT repeats Arm-DNA-bind_4 PF14657.6 CCH60119.1 - 0.57 10.0 4.2 2.4 8.0 4.2 2.2 1 0 0 1 1 1 0 Arm DNA-binding domain Ribosomal_S27e PF01667.17 CCH60120.1 - 5.2e-30 102.9 2.6 6.5e-30 102.6 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CCH60120.1 - 0.008 16.4 0.8 0.0097 16.1 0.8 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CCH60120.1 - 0.03 13.8 4.7 0.046 13.3 4.7 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Rsm22 PF09243.10 CCH60121.1 - 5e-23 81.8 0.0 1.2e-07 31.3 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CCH60121.1 - 0.0048 16.7 0.0 0.016 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain HGTP_anticodon2 PF12745.7 CCH60122.1 - 7.3e-88 294.5 5.7 7.3e-88 294.5 5.7 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 CCH60122.1 - 4.3e-69 232.8 1.6 2.8e-39 135.1 0.1 3.7 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60122.1 - 6.4e-37 127.2 0.2 8.2e-20 71.2 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CCH60122.1 - 1.2e-19 70.7 3.9 6.3e-19 68.4 3.9 2.4 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CCH60122.1 - 3.4e-14 52.8 0.0 6.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 CCH60122.1 - 1.3e-06 27.9 0.0 0.022 14.1 0.0 2.6 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 CCH60122.1 - 0.044 13.4 0.2 9.7 5.7 0.0 3.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCH60122.1 - 0.064 13.2 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CCH60122.1 - 0.09 12.1 0.1 0.41 10.0 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRP-S26 PF14943.6 CCH60122.1 - 3.1 7.7 15.1 0.43 10.5 10.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PAP2 PF01569.21 CCH60123.1 - 8.7e-28 96.8 2.1 1.2e-27 96.4 1.2 1.6 1 1 1 2 2 2 1 PAP2 superfamily KdpA PF03814.15 CCH60123.1 - 0.047 11.9 0.3 0.093 10.9 0.0 1.5 1 1 0 1 1 1 0 Potassium-transporting ATPase A subunit PAP2_3 PF14378.6 CCH60123.1 - 0.065 12.9 7.9 0.26 10.9 6.2 2.4 1 1 0 1 1 1 0 PAP2 superfamily UPF0154 PF03672.13 CCH60123.1 - 0.11 12.5 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) MAGE PF01454.19 CCH60124.1 - 1.5e-47 162.0 0.5 1.9e-47 161.7 0.5 1.1 1 0 0 1 1 1 1 MAGE family SUa-2TM PF18179.1 CCH60124.1 - 0.026 13.8 3.2 0.038 13.3 3.2 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain FAD_binding_1 PF00667.20 CCH60125.1 - 1.9e-66 223.8 0.0 3.4e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCH60125.1 - 3.3e-26 92.2 0.5 6.2e-26 91.3 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCH60125.1 - 4e-21 75.7 0.0 1.1e-20 74.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.10 CCH60125.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) HAD_2 PF13419.6 CCH60126.1 - 1.9e-18 67.2 0.0 2.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCH60126.1 - 1.2e-05 25.7 0.0 0.0006 20.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCH60126.1 - 0.00033 20.6 0.1 0.00053 20.0 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like ADH_zinc_N PF00107.26 CCH60126.1 - 0.0017 18.4 0.1 0.0028 17.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HAD PF12710.7 CCH60126.1 - 0.06 13.7 0.0 0.1 13.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase RNase_H2-Ydr279 PF09468.10 CCH60127.1 - 8.8e-20 71.5 0.4 1.8e-19 70.5 0.4 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CCH60127.1 - 2.8e-06 27.5 0.1 1.2e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain Nramp PF01566.18 CCH60128.1 - 5.9e-92 308.4 15.6 1.1e-91 307.5 15.6 1.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Med20 PF08612.11 CCH60129.1 - 7.2e-30 104.0 0.1 7.9e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex XisH PF08814.10 CCH60129.1 - 0.039 14.1 0.6 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 XisH protein DUF5100 PF17029.5 CCH60129.1 - 0.19 11.6 7.9 0.043 13.7 3.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF5100) CTD_bind PF04818.13 CCH60130.1 - 2e-11 44.5 0.1 1e-10 42.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Aldedh PF00171.22 CCH60131.1 - 2.8e-112 375.6 0.0 3.5e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNB PF00773.19 CCH60132.1 - 1.7e-50 172.3 2.9 1.7e-50 172.3 2.9 1.9 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CCH60132.1 - 6.4e-22 77.4 0.1 1.6e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CCH60132.1 - 2.4e-21 75.9 0.0 9.1e-21 74.0 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CCH60132.1 - 1.4e-06 28.4 0.0 5e-05 23.4 0.0 2.9 2 0 0 2 2 2 1 Cold shock domain Rrp44_CSD1 PF17216.3 CCH60132.1 - 0.00094 18.9 0.0 0.0026 17.5 0.0 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CCH60132.1 - 0.062 13.0 0.1 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain Aldedh PF00171.22 CCH60133.1 - 6.6e-95 318.3 0.0 1.1e-94 317.5 0.0 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Brr6_like_C_C PF10104.9 CCH60134.1 - 5e-38 129.9 4.1 7.6e-38 129.3 4.1 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Endomucin PF07010.12 CCH60134.1 - 0.059 13.4 6.3 0.096 12.6 6.3 1.3 1 0 0 1 1 1 0 Endomucin HDA2-3 PF11496.8 CCH60135.1 - 6.3e-56 189.7 20.3 6.3e-56 189.7 20.3 3.4 2 2 1 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 SlyX PF04102.12 CCH60135.1 - 2.9 8.6 13.6 0.85 10.3 0.9 4.3 3 1 2 5 5 5 0 SlyX Laminin_II PF06009.12 CCH60135.1 - 5.1 7.1 24.7 0.091 12.8 6.1 3.9 3 1 0 3 3 3 0 Laminin Domain II Sec23_trunk PF04811.15 CCH60136.1 - 1.9e-15 57.1 0.0 3.5e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 CCH60136.1 - 0.0015 18.5 3.7 0.0036 17.3 3.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger PHD PF00628.29 CCH60136.1 - 0.019 14.8 2.4 0.047 13.6 2.4 1.6 1 0 0 1 1 1 0 PHD-finger Vps36-NZF-N PF16988.5 CCH60136.1 - 0.024 14.0 0.1 0.073 12.5 0.1 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FlhC PF05280.11 CCH60136.1 - 0.2 11.3 0.8 0.49 10.1 0.8 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) zinc_ribbon_10 PF10058.9 CCH60136.1 - 0.45 10.3 2.1 0.92 9.3 2.1 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Elf1 PF05129.13 CCH60136.1 - 2.6 8.2 5.7 11 6.1 0.2 3.3 2 1 2 4 4 4 0 Transcription elongation factor Elf1 like Mhr1 PF12829.7 CCH60137.1 - 4.9e-25 87.4 0.1 9.4e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination OSCP PF00213.18 CCH60138.1 - 8.4e-44 149.7 3.5 9.8e-44 149.5 3.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Tipalpha PF16753.5 CCH60138.1 - 0.051 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 TNF-alpha-Inducing protein of Helicobacter Pih1_fungal_CS PF18482.1 CCH60139.1 - 2.5e-30 104.8 5.3 2.5e-30 104.8 5.3 2.0 2 0 0 2 2 2 1 Fungal Pih1 CS domain PIH1 PF08190.12 CCH60139.1 - 1.1e-21 77.0 3.3 1.1e-20 73.7 3.3 2.2 1 1 0 1 1 1 1 PIH1 N-terminal domain DUF349 PF03993.12 CCH60139.1 - 0.027 14.8 0.2 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) PIG-F PF06699.11 CCH60140.1 - 3.2e-24 86.1 14.1 4e-23 82.5 13.7 2.2 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF5079 PF16882.5 CCH60140.1 - 0.007 16.3 8.4 0.0088 15.9 8.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5079) DUF5408 PF17402.2 CCH60140.1 - 0.051 13.5 2.2 0.072 13.0 1.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5408) AIM24 PF01987.17 CCH60141.1 - 4.7e-14 52.6 0.0 6.9e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.18 CCH60142.1 - 3.4e-07 30.3 7.7 6.1e-07 29.5 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 CCH60143.1 - 8.5e-48 162.6 0.2 1.1e-47 162.2 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Epimerase PF01370.21 CCH60144.1 - 1.5e-19 70.5 0.0 2.4e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CCH60144.1 - 7.4e-11 41.7 0.0 2.2e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CCH60144.1 - 1.1e-10 41.4 0.4 1.6e-10 41.0 0.4 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CCH60144.1 - 1.9e-07 30.4 0.2 2.8e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CCH60144.1 - 6.1e-06 26.3 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CCH60144.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCH60144.1 - 0.011 15.3 0.0 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 CCH60144.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 CCH60144.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF3463 PF11946.8 CCH60144.1 - 0.074 12.9 0.7 0.18 11.6 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3463) Epimerase PF01370.21 CCH60145.1 - 1.5e-16 60.6 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCH60145.1 - 1.9e-12 46.8 0.4 2.8e-12 46.2 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCH60145.1 - 1.2e-11 44.3 0.0 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 CCH60145.1 - 2.8e-09 36.9 0.8 1.4e-07 31.3 0.2 2.4 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CCH60145.1 - 5.3e-06 25.8 0.4 4.2e-05 22.8 0.2 2.4 2 1 0 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCH60145.1 - 0.00015 21.4 0.1 0.0006 19.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CCH60145.1 - 0.00016 21.6 0.0 0.0004 20.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CCH60145.1 - 0.00084 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 CCH60145.1 - 0.0013 18.2 0.0 0.0047 16.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CCH60145.1 - 0.043 12.9 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 CCH60146.1 - 7.1e-12 45.3 0.1 1.8e-11 44.0 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCH60146.1 - 7.1e-11 41.6 0.0 8.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCH60146.1 - 4.5e-08 32.6 0.0 5.3e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CCH60146.1 - 6.9e-07 29.0 0.1 1.4e-06 27.9 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCH60146.1 - 1.8e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CCH60146.1 - 0.0063 16.0 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CCH60146.1 - 0.0071 15.9 0.1 0.027 14.0 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family KR PF08659.10 CCH60146.1 - 0.011 15.6 0.0 0.037 14.0 0.0 1.9 2 1 0 2 2 2 0 KR domain LIAS_N PF16881.5 CCH60146.1 - 0.039 14.4 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family HIT PF01230.23 CCH60147.1 - 6.1e-24 84.6 0.1 1.7e-23 83.2 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CCH60147.1 - 0.00057 20.3 0.3 0.0012 19.4 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Med21 PF11221.8 CCH60148.1 - 7.4e-47 159.2 5.6 9.3e-47 158.9 5.6 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 CCH60148.1 - 0.00031 20.8 2.2 0.0009 19.3 1.9 2.0 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Katanin_con80 PF13925.6 CCH60148.1 - 0.0026 17.8 0.4 0.012 15.6 0.3 1.9 2 0 0 2 2 2 1 con80 domain of Katanin DUF2200 PF09966.9 CCH60148.1 - 0.0058 16.8 0.5 0.2 11.8 0.0 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2200) Rsa3 PF14615.6 CCH60148.1 - 0.18 11.4 0.3 8.9 6.0 0.0 2.9 3 0 0 3 3 3 0 Ribosome-assembly protein 3 SlyX PF04102.12 CCH60148.1 - 0.69 10.6 3.6 47 4.7 0.0 3.3 3 1 0 3 3 3 0 SlyX DUF1492 PF07374.11 CCH60148.1 - 0.71 10.1 4.7 3.5 7.9 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) Pyrid_oxidase_2 PF13883.6 CCH60149.1 - 0.63 10.0 3.5 0.66 9.9 0.4 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase HSP70 PF00012.20 CCH60151.1 - 3.7e-72 243.4 1.2 3.7e-72 243.4 1.2 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CCH60151.1 - 9.4e-11 41.1 0.0 1.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DEAD PF00270.29 CCH60152.1 - 1.5e-48 164.9 0.0 2.7e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60152.1 - 1.3e-31 109.2 0.2 1e-30 106.3 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CCH60152.1 - 0.0034 17.7 0.0 0.026 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain GLTP PF08718.11 CCH60152.1 - 0.03 14.6 0.0 0.099 12.9 0.0 1.9 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) TFB6 PF17110.5 CCH60152.1 - 1.7 8.4 8.3 3.9 7.2 8.3 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pox_Ag35 PF03286.14 CCH60152.1 - 3.5 7.4 18.5 6.4 6.5 18.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 CCH60152.1 - 4 7.1 9.5 7.6 6.2 8.7 1.9 2 0 0 2 2 2 0 FAM176 family Atrophin-1 PF03154.15 CCH60152.1 - 7.2 4.8 7.1 9.8 4.3 7.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family FYVE PF01363.21 CCH60153.1 - 1.7e-15 56.9 13.8 1.7e-15 56.9 13.8 3.2 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CCH60153.1 - 4.5e-07 30.1 2.3 4.5e-07 30.1 2.3 3.9 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 CCH60153.1 - 1.4e-05 24.7 5.4 5e-05 22.9 5.4 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CCH60153.1 - 0.0012 18.7 2.1 0.0012 18.7 2.1 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.9 CCH60153.1 - 2.4 6.6 10.3 3.6 6.0 10.3 1.2 1 0 0 1 1 1 0 Macoilin family BHD_3 PF10405.9 CCH60154.1 - 1.3e-15 57.5 0.1 2.9e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CCH60154.1 - 5.8e-13 48.5 0.0 1.6e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 CCH60154.1 - 2.3e-05 24.1 0.2 9.5e-05 22.1 0.2 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CCH60154.1 - 0.12 13.3 0.0 0.63 11.0 0.0 2.3 1 1 0 1 1 1 0 Rad4 beta-hairpin domain 2 MaoC_dehydrat_N PF13452.6 CCH60155.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase DS PF01916.17 CCH60156.1 - 1.1e-133 444.9 0.1 1.3e-133 444.7 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Met_10 PF02475.16 CCH60157.1 - 2.1e-74 249.6 0.0 4.6e-74 248.5 0.0 1.6 1 1 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 CCH60157.1 - 0.0091 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Ribosomal_L24e PF01246.20 CCH60159.1 - 6.5e-33 112.8 3.6 1.3e-32 111.8 3.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Presenilin PF01080.17 CCH60159.1 - 9.1 4.9 5.7 9 4.9 5.7 1.1 1 0 0 1 1 1 0 Presenilin Pam16 PF03656.13 CCH60160.1 - 2.3e-05 24.4 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CCH60160.1 - 0.0028 17.7 0.2 0.0054 16.8 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain SMC_Nse1 PF07574.13 CCH60161.1 - 5.1e-50 170.1 0.3 6.3e-50 169.8 0.3 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CCH60161.1 - 8.6e-11 42.0 11.8 2.3e-10 40.6 11.8 1.8 1 0 0 1 1 1 1 RING-like domain CMS1 PF14617.6 CCH60162.1 - 1.3e-18 67.3 18.0 7.3e-18 64.8 18.0 2.3 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Presenilin PF01080.17 CCH60162.1 - 0.3 9.8 3.8 0.39 9.4 3.8 1.1 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 CCH60163.1 - 3.2e-30 105.3 22.0 3.2e-30 105.3 22.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Ssl1 PF04056.14 CCH60165.1 - 8.2e-85 283.5 0.0 1.1e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 CCH60165.1 - 2.6e-25 88.4 11.4 2.6e-25 88.4 11.4 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CCH60165.1 - 2e-14 54.1 0.0 4.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CCH60165.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1451 PF07295.11 CCH60165.1 - 1.5 8.9 4.5 4.6 7.3 4.5 1.9 1 0 0 1 1 1 0 Zinc-ribbon containing domain IBR PF01485.21 CCH60165.1 - 1.6 9.0 19.5 0.038 14.2 6.6 2.9 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Tfb4 PF03850.14 CCH60165.1 - 1.8 8.0 8.1 4 6.9 8.1 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 zf-HIT PF04438.16 CCH60165.1 - 2.6 8.0 20.2 0.43 10.5 6.3 3.3 3 0 0 3 3 3 0 HIT zinc finger DZR PF12773.7 CCH60165.1 - 5.2 7.2 22.7 0.66 10.1 6.7 3.4 2 1 0 2 2 2 0 Double zinc ribbon PP2C PF00481.21 CCH60166.1 - 1.5e-54 185.3 0.0 1.5e-54 185.3 0.0 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 CCH60166.1 - 4.9e-33 112.7 87.2 1.4e-09 37.6 4.8 10.4 8 3 2 11 11 11 7 Leucine rich repeat LRR_4 PF12799.7 CCH60166.1 - 1.2e-27 95.5 99.0 0.00016 22.0 5.4 13.6 11 2 1 13 13 13 8 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CCH60166.1 - 4.2e-26 91.7 0.0 9.5e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CCH60166.1 - 0.001 18.6 6.5 0.001 18.6 6.5 4.7 2 1 2 4 4 4 2 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 CCH60166.1 - 0.0015 18.2 0.0 0.0063 16.2 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain PP2C_2 PF13672.6 CCH60166.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein phosphatase 2C LRR_6 PF13516.6 CCH60166.1 - 0.31 11.2 47.4 2.1 8.6 0.6 13.1 14 0 0 14 14 14 0 Leucine Rich repeat PH_12 PF16457.5 CCH60167.1 - 2.6e-08 34.5 0.1 4.7e-07 30.4 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain MMM1 PF10296.9 CCH60168.1 - 7.9e-132 439.3 2.7 1.1e-131 438.8 2.7 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 CRR7 PF12095.8 CCH60168.1 - 0.00072 20.0 0.1 0.11 13.0 0.0 2.7 2 0 0 2 2 2 2 Protein CHLORORESPIRATORY REDUCTION 7 RSN1_7TM PF02714.15 CCH60169.1 - 1.4e-66 224.7 30.5 1.4e-66 224.7 30.5 3.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCH60169.1 - 2.1e-29 102.3 5.5 2.1e-29 102.3 5.5 3.1 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCH60169.1 - 4.2e-06 27.1 0.0 1e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter EI24 PF07264.11 CCH60169.1 - 0.77 10.0 25.6 6.1 7.1 20.8 3.2 2 2 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) RRM_1 PF00076.22 CCH60170.1 - 0.021 14.6 0.2 0.09 12.6 0.1 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BNIP2 PF12496.8 CCH60170.1 - 0.24 11.9 7.0 0.074 13.5 2.5 2.5 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Pyrophosphatase PF00719.19 CCH60171.1 - 8.5e-53 178.4 0.1 1.2e-52 177.9 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase WD40 PF00400.32 CCH60172.1 - 1.2e-09 38.6 5.2 0.15 13.0 0.0 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH60172.1 - 8.4e-07 29.2 0.0 0.0028 17.9 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH60172.1 - 0.0004 20.3 0.0 0.03 14.2 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCH60172.1 - 0.097 11.6 0.1 0.49 9.3 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CCH60172.1 - 4.5 7.3 6.6 11 6.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Cue1_U7BR PF18499.1 CCH60173.1 - 1.3e-23 82.7 1.8 2.8e-23 81.7 1.8 1.6 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 CUE PF02845.16 CCH60173.1 - 1.1e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 CUE domain OATP PF03137.20 CCH60173.1 - 0.23 9.7 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SAP30_Sin3_bdg PF13867.6 CCH60174.1 - 5e-09 36.3 0.6 2.6e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Glyco_transf_20 PF00982.21 CCH60175.1 - 2e-158 528.0 2.6 4e-158 527.0 1.6 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCH60175.1 - 2.3e-31 108.8 0.0 7.3e-31 107.1 0.0 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase eIF-1a PF01176.19 CCH60176.1 - 1.7e-20 72.5 0.1 2.5e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Homeobox_KN PF05920.11 CCH60177.1 - 3.5e-17 62.0 0.5 3.5e-17 62.0 0.5 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CCH60177.1 - 2.6e-05 24.0 0.7 0.00013 21.8 0.2 2.3 2 0 0 2 2 2 1 Homeodomain RCC1 PF00415.18 CCH60179.1 - 2.3e-60 201.0 0.1 1.6e-07 31.8 0.0 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCH60179.1 - 7.1e-35 118.1 31.4 2.8e-07 30.1 2.1 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Na_trans_assoc PF06512.13 CCH60179.1 - 0.014 15.7 2.7 0.024 14.9 2.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Bystin PF05291.11 CCH60180.1 - 5.7e-122 406.6 0.0 9.4e-122 405.9 0.0 1.2 1 0 0 1 1 1 1 Bystin Use1 PF09753.9 CCH60181.1 - 4.6e-14 52.7 4.3 1.6e-13 50.9 4.3 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 Bacillus_HBL PF05791.11 CCH60181.1 - 0.018 14.8 1.7 0.018 14.8 1.7 3.1 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4829 PF16111.5 CCH60181.1 - 0.31 11.8 8.8 0.18 12.6 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4829) DUF4407 PF14362.6 CCH60181.1 - 2.3 7.5 9.6 7.8 5.8 9.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MMR_HSR1 PF01926.23 CCH60182.1 - 1.4e-16 60.6 0.5 6.9e-15 55.1 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH60182.1 - 3.1e-08 33.3 0.2 2.8e-06 26.9 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCH60182.1 - 8.3e-07 29.1 0.3 0.00077 19.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CCH60182.1 - 0.0012 18.2 0.1 0.0027 17.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CCH60182.1 - 2.1 8.3 10.3 0.1 12.7 2.1 3.1 3 1 0 3 3 3 0 Dynamin family SNF2_N PF00176.23 CCH60183.1 - 3.3e-73 246.4 0.3 3.3e-73 246.4 0.3 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCH60183.1 - 2.7e-38 130.5 0.8 2.7e-38 130.5 0.8 3.8 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 CCH60183.1 - 1.1e-29 103.4 7.0 1.1e-29 103.4 7.0 3.4 2 0 0 2 2 2 1 HAND Helicase_C PF00271.31 CCH60183.1 - 9.8e-19 67.7 0.8 2.7e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH60183.1 - 1.1e-11 45.0 4.3 1.6e-10 41.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCH60183.1 - 1.8e-10 40.5 0.5 4.8e-10 39.1 0.5 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CCH60183.1 - 4.5e-05 23.3 0.0 0.00017 21.4 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CCH60183.1 - 0.021 14.5 0.1 0.071 12.7 0.1 1.9 1 0 0 1 1 1 0 DEAD_2 Myb_DNA-binding PF00249.31 CCH60183.1 - 0.048 13.9 0.0 11 6.3 0.0 3.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain AAA_14 PF13173.6 CCH60183.1 - 0.05 13.7 0.4 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RT_RNaseH_2 PF17919.1 CCH60184.1 - 3.9e-26 91.0 0.0 8.9e-26 89.9 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH60184.1 - 5.9e-24 84.4 0.0 1.3e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCH60184.1 - 5.6e-12 45.6 0.3 2e-11 43.8 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CCH60184.1 - 2.4e-09 37.4 0.0 8.2e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.17 CCH60185.1 - 3e-14 53.0 0.1 1.9e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.23 CCH60185.1 - 0.015 15.4 0.7 0.034 14.2 0.7 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF4939 PF16297.5 CCH60185.1 - 0.022 14.6 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Corona_NSP4_C PF16348.5 CCH60185.1 - 0.37 11.6 2.3 0.42 11.5 0.6 2.0 2 1 0 2 2 2 0 Coronavirus nonstructural protein 4 C-terminus Glyco_hydro_76 PF03663.14 CCH60186.1 - 6.2e-146 486.6 15.1 8.7e-146 486.1 15.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PHBC_N PF12551.8 CCH60186.1 - 0.51 10.2 1.8 3.1 7.7 0.1 2.6 3 0 0 3 3 3 0 Poly-beta-hydroxybutyrate polymerase N terminal DASH_Dam1 PF08653.10 CCH60187.1 - 6.7e-24 83.5 0.2 6.7e-24 83.5 0.2 2.5 2 0 0 2 2 2 1 DASH complex subunit Dam1 Sas6_CC PF18594.1 CCH60187.1 - 0.48 10.2 3.2 1.4 8.8 3.2 1.8 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Myb_DNA-bind_3 PF12776.7 CCH60187.1 - 1.3 10.1 4.9 17 6.5 0.5 2.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SH2_2 PF14633.6 CCH60188.1 - 7.6e-69 231.4 2.7 7.6e-69 231.4 2.7 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 CCH60188.1 - 1.7e-63 212.9 0.0 7.9e-63 210.7 0.0 2.3 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CCH60188.1 - 7.4e-46 154.8 0.0 3.2e-45 152.8 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CCH60188.1 - 5e-36 123.6 1.8 2.3e-35 121.5 1.8 2.2 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CCH60188.1 - 7.3e-20 71.4 20.0 7.3e-20 71.4 20.0 5.5 4 1 1 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.24 CCH60188.1 - 5.9e-13 48.7 0.1 1.9e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 CCH60188.1 - 0.00086 20.2 0.6 0.00086 20.2 0.6 4.0 4 2 0 5 5 5 1 HHH domain HHH_3 PF12836.7 CCH60188.1 - 0.1 12.8 0.3 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Tex_YqgF PF16921.5 CCH60188.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 Tex protein YqgF-like domain Tom6 PF17112.5 CCH60188.1 - 0.22 11.1 0.0 0.52 9.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal LSM14 PF12701.7 CCH60189.1 - 3.5e-25 87.9 0.0 6.8e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CCH60189.1 - 1.1e-08 35.9 9.4 1.1e-08 35.9 9.4 3.8 2 1 1 3 3 3 1 FDF domain SM-ATX PF14438.6 CCH60189.1 - 0.003 17.6 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain CNH PF00780.22 CCH60190.1 - 0.0057 16.3 1.5 0.02 14.5 0.1 2.2 2 0 0 2 2 2 1 CNH domain LisH PF08513.11 CCH60190.1 - 0.087 12.8 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 LisH Ribosom_S12_S23 PF00164.25 CCH60191.1 - 4.8e-48 161.5 0.2 6.3e-48 161.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nup54 PF13874.6 CCH60192.1 - 1.3e-38 132.3 4.0 1.3e-38 132.3 4.0 2.8 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CCH60192.1 - 1.8e-16 60.8 122.0 1.1e-07 32.6 41.5 4.6 1 1 3 4 4 4 3 Nucleoporin FG repeat region Ammonium_transp PF00909.21 CCH60193.1 - 1.1e-118 396.4 20.7 1.3e-118 396.2 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SelP_N PF04592.14 CCH60193.1 - 0.42 10.0 20.4 0.66 9.3 20.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM163 PF15069.6 CCH60193.1 - 0.69 10.3 3.4 1.6 9.2 3.4 1.6 1 0 0 1 1 1 0 FAM163 family SDA1 PF05285.12 CCH60193.1 - 4.1 6.7 15.4 5.4 6.3 15.4 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CCH60193.1 - 7.2 4.8 15.1 9.3 4.4 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Acyltransferase PF01553.21 CCH60194.1 - 4.1e-12 45.9 0.0 6.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Peptidase_A4 PF01828.17 CCH60194.1 - 0.015 14.8 0.5 0.034 13.6 0.5 1.5 1 0 0 1 1 1 0 Peptidase A4 family TssO PF17561.2 CCH60194.1 - 0.064 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO Kinesin PF00225.23 CCH60195.1 - 5e-99 331.4 8.9 5e-99 331.4 8.9 3.1 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CCH60195.1 - 4.5e-52 176.0 2.2 4.5e-52 176.0 2.2 2.8 2 0 0 2 2 2 1 Microtubule binding EKAL PF17986.1 CCH60195.1 - 0.02 14.9 0.8 0.02 14.9 0.8 3.0 3 0 0 3 3 3 0 EMP3-KAHRP-like N-terminal domain DUF2737 PF10930.8 CCH60195.1 - 0.24 11.0 4.4 0.73 9.4 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) Metallophos PF00149.28 CCH60196.1 - 1.1e-32 114.3 0.2 1.8e-32 113.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CCH60196.1 - 8.1e-22 77.3 0.1 1.8e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 CCH60196.1 - 1.2e-14 53.3 0.3 0.00018 21.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCH60196.1 - 7.3e-14 50.7 0.0 0.00081 19.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH60196.1 - 7.3e-07 28.8 0.1 0.05 13.3 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CCH60196.1 - 2.4e-05 24.2 0.2 1.5 9.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH60196.1 - 0.0026 18.0 0.2 0.037 14.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCH60196.1 - 0.0042 17.2 0.0 0.009 16.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCH60196.1 - 0.0057 16.7 0.0 0.059 13.4 0.0 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CCH60196.1 - 0.019 15.6 0.0 1.6 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCH60196.1 - 0.05 13.9 0.0 15 5.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CCH60196.1 - 0.083 13.0 0.1 0.6 10.2 0.1 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 CCH60196.1 - 0.12 12.9 0.0 6.5 7.4 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat EMP24_GP25L PF01105.24 CCH60198.1 - 6.6e-46 156.5 0.3 7.8e-46 156.3 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SBDS PF01172.18 CCH60198.1 - 0.0031 17.5 0.1 0.0064 16.5 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein UPF0370 PF13980.6 CCH60198.1 - 0.29 11.2 1.6 0.84 9.7 1.6 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) WD40 PF00400.32 CCH60199.1 - 1.2e-14 54.4 1.7 9.2e-06 26.3 0.2 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH60199.1 - 4.6e-08 33.2 0.6 0.099 13.0 0.0 4.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH60199.1 - 2.1e-06 27.8 0.3 0.0018 18.2 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CCH60199.1 - 0.0039 16.0 0.5 0.059 12.1 0.1 2.3 2 1 0 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 CCH60199.1 - 0.0068 15.0 0.0 0.015 13.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome D1 heme domain DUF1623 PF07785.11 CCH60199.1 - 0.024 14.8 1.1 0.094 12.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) Pectate_lyase_3 PF12708.7 CCH60199.1 - 0.088 12.6 2.8 0.15 11.9 2.8 1.3 1 0 0 1 1 1 0 Pectate lyase superfamily protein Fungal_trans PF04082.18 CCH60200.1 - 6.1e-07 28.7 0.1 1.8e-06 27.2 0.1 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH60200.1 - 0.00015 21.8 9.0 0.00026 21.0 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 CCH60200.1 - 0.07 13.8 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RecR PF02132.15 CCH60200.1 - 7.6 6.2 10.3 0.78 9.4 3.2 2.3 2 0 0 2 2 2 0 RecR protein Cation_ATPase_C PF00689.21 CCH60201.1 - 4.4e-40 137.3 12.9 4.4e-40 137.3 12.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CCH60201.1 - 9.8e-37 126.2 0.5 9.8e-37 126.2 0.5 3.3 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 CCH60201.1 - 1.3e-20 73.3 0.0 2.6e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCH60201.1 - 2.5e-16 60.6 0.0 1.6e-12 48.2 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCH60201.1 - 1.8e-09 37.2 0.0 4.7e-09 35.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCH60201.1 - 9.1e-05 22.3 0.2 0.00046 20.0 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Spo7 PF03907.13 CCH60201.1 - 0.032 13.7 0.1 0.032 13.7 0.1 2.3 3 0 0 3 3 3 0 Spo7-like protein DUF2975 PF11188.8 CCH60201.1 - 0.51 10.2 6.3 2.5 8.0 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF2207 PF09972.9 CCH60201.1 - 8.7 5.0 8.1 6.7 5.4 1.9 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) tRNA_int_endo PF01974.17 CCH60202.1 - 3.8e-14 52.5 0.0 9.4e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain E1-E2_ATPase PF00122.20 CCH60203.1 - 7.2e-47 159.2 2.0 2e-46 157.8 2.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH60203.1 - 6e-20 72.4 0.1 2e-19 70.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCH60203.1 - 1.8e-11 43.5 0.0 1.8e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCH60203.1 - 0.004 16.9 0.1 0.0083 15.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH60203.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) PUF PF00806.19 CCH60204.1 - 2.2e-61 200.2 18.8 1e-08 34.4 0.1 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat CPL PF08144.11 CCH60204.1 - 0.0046 17.3 0.3 4.9 7.5 0.1 3.5 2 2 1 3 3 3 2 CPL (NUC119) domain Reg_prop PF07494.11 CCH60204.1 - 0.67 10.4 2.2 61 4.4 0.2 3.9 3 0 0 3 3 3 0 Two component regulator propeller Fungal_trans PF04082.18 CCH60205.1 - 2.2e-25 89.2 8.2 2.2e-25 89.2 8.2 3.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH60205.1 - 6.9e-10 38.9 13.2 1.3e-09 38.0 13.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIDA PF01134.22 CCH60205.1 - 0.091 11.8 0.1 0.22 10.6 0.1 1.6 1 0 0 1 1 1 0 Glucose inhibited division protein A ERG4_ERG24 PF01222.17 CCH60206.1 - 2.3e-179 596.7 30.6 2.6e-179 596.5 30.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Rsc14 PF08586.10 CCH60207.1 - 1.4e-36 125.2 4.7 1.4e-36 125.2 4.7 1.8 2 0 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit zinc_ribbon_10 PF10058.9 CCH60207.1 - 0.015 15.0 0.3 0.073 12.8 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein MMM1 PF10296.9 CCH60207.1 - 0.67 8.9 3.1 1.3 8.0 3.1 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Proteasome PF00227.26 CCH60208.1 - 2e-44 151.3 0.0 3.1e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH60208.1 - 2e-15 56.1 0.1 3.8e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cullin_binding PF03556.15 CCH60208.1 - 0.15 12.5 0.7 0.26 11.7 0.0 1.8 3 0 0 3 3 3 0 Cullin binding DUF962 PF06127.11 CCH60209.1 - 2.3e-22 78.9 6.1 1.7e-21 76.1 6.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SH3_1 PF00018.28 CCH60210.1 - 7.2e-33 112.0 4.8 7.7e-12 44.6 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 CCH60210.1 - 1.2e-32 111.5 0.0 2.2e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 CCH60210.1 - 5.1e-32 109.5 8.7 7.2e-12 45.0 0.5 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 CCH60210.1 - 1.2e-25 89.0 0.0 2.2e-07 30.5 0.0 4.7 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 CCH60210.1 - 0.00038 20.4 0.0 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SpoVAC_SpoVAEB PF03862.13 CCH60210.1 - 1.2 9.4 7.3 40 4.5 0.3 3.9 2 2 3 5 5 5 0 SpoVAC/SpoVAEB sporulation membrane protein WD40 PF00400.32 CCH60211.1 - 3.7e-32 109.8 18.6 6.4e-09 36.3 0.0 8.0 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH60211.1 - 2.1e-18 66.4 0.2 0.0025 18.1 0.0 6.3 3 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 CCH60211.1 - 5.9e-14 52.3 0.4 2.7e-13 50.2 0.1 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40_like PF17005.5 CCH60211.1 - 3.4e-11 43.0 0.1 0.018 14.4 0.0 3.8 4 0 0 4 4 4 3 WD40-like domain HIRA_B PF09453.10 CCH60211.1 - 4.3e-08 32.8 0.1 4.3e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 CCH60211.1 - 2.7e-06 27.2 0.0 2.8 8.0 0.0 4.4 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CCH60211.1 - 9.5e-05 21.5 0.1 0.43 9.5 0.0 4.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CCH60211.1 - 0.016 14.6 0.2 0.17 11.2 0.0 2.8 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Importin_rep_3 PF18806.1 CCH60212.1 - 0.00012 22.1 0.0 0.00046 20.2 0.0 2.1 1 0 0 1 1 1 1 Importin 13 repeat Forkhead PF00250.18 CCH60212.1 - 1.8 8.9 5.4 7.7 6.8 0.4 4.1 3 1 0 3 3 3 0 Forkhead domain ATE_C PF04377.15 CCH60213.1 - 1.6e-42 145.3 3.9 3.4e-42 144.3 3.9 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CCH60213.1 - 2.3e-23 82.4 2.7 5.1e-23 81.3 2.7 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus CK_II_beta PF01214.18 CCH60214.1 - 2.7e-60 203.3 0.0 3.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CHD5 PF04420.14 CCH60215.1 - 6.2e-39 133.4 1.4 8.4e-39 133.0 1.4 1.1 1 0 0 1 1 1 1 CHD5-like protein MOR2-PAG1_N PF14222.6 CCH60216.1 - 0.0066 15.5 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Acyltransferase PF01553.21 CCH60217.1 - 2.3e-06 27.3 0.0 3e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase NOA36 PF06524.12 CCH60217.1 - 1.7 7.9 20.2 3 7.1 20.2 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.9 CCH60217.1 - 4.3 7.3 18.8 7.6 6.5 18.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Formyl_trans_N PF00551.19 CCH60218.1 - 1.9e-28 99.4 0.0 3.5e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CCH60218.1 - 0.0015 18.7 0.0 0.004 17.4 0.0 1.8 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain Cgr1 PF03879.14 CCH60219.1 - 1.5e-32 112.2 28.8 1.7e-32 112.0 28.8 1.0 1 0 0 1 1 1 1 Cgr1 family LppC PF04348.13 CCH60219.1 - 0.037 12.8 8.0 0.04 12.7 8.0 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein DUF2048 PF09752.9 CCH60219.1 - 0.04 13.0 4.1 0.05 12.7 4.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Asp-B-Hydro_N PF05279.11 CCH60219.1 - 0.4 10.7 10.4 0.42 10.6 10.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FapA PF03961.13 CCH60219.1 - 0.51 8.9 8.3 0.55 8.8 8.3 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Macoilin PF09726.9 CCH60219.1 - 5.5 5.4 18.6 6.7 5.1 18.6 1.0 1 0 0 1 1 1 0 Macoilin family PPR_2 PF13041.6 CCH60220.1 - 6e-16 58.4 3.9 3.3e-11 43.2 0.1 4.2 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 CCH60220.1 - 5.6e-12 45.1 0.3 1.5e-06 28.1 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 CCH60220.1 - 3.6e-06 26.5 0.3 9.3e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CCH60220.1 - 0.00036 20.5 0.4 0.038 14.1 0.1 3.2 1 1 1 2 2 2 2 Pentatricopeptide repeat domain GAS PF13851.6 CCH60220.1 - 0.00058 19.3 12.8 0.0027 17.1 12.8 2.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding PPR_1 PF12854.7 CCH60220.1 - 0.0012 18.5 0.0 0.0094 15.6 0.0 2.4 2 0 0 2 2 2 1 PPR repeat Lebercilin PF15619.6 CCH60220.1 - 0.011 15.3 8.6 0.011 15.3 8.6 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Jnk-SapK_ap_N PF09744.9 CCH60220.1 - 0.44 10.8 9.4 1.1 9.4 9.4 1.7 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CCH60220.1 - 9.3 6.8 16.2 0.71 10.4 9.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF2838 PF10998.8 CCH60221.1 - 2.6e-40 137.1 11.4 2.6e-40 137.1 11.4 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Ribosomal_L7Ae PF01248.26 CCH60222.1 - 6.3e-24 83.5 0.1 7.1e-24 83.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AGA2 PF17366.2 CCH60223.1 - 3.4e-26 90.7 2.8 4.3e-26 90.4 2.8 1.1 1 0 0 1 1 1 1 A-agglutinin-binding subunit Aga2 TBPIP PF07106.13 CCH60224.1 - 1e-11 44.5 0.2 2.5e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF4490 PF14892.6 CCH60225.1 - 1.7 8.8 8.5 0.31 11.1 3.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4490) Pox_Ag35 PF03286.14 CCH60226.1 - 1.3 8.8 8.0 2.5 7.8 8.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Isochorismatase PF00857.20 CCH60227.1 - 2.5e-26 92.9 0.0 3e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Gly_transf_sug PF04488.15 CCH60228.1 - 2.4e-14 53.8 0.8 7.5e-14 52.2 0.1 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TFIIS_M PF07500.14 CCH60229.1 - 5.7e-26 91.2 8.8 1.1e-25 90.2 0.6 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CCH60229.1 - 1.9e-17 62.8 6.4 3.2e-17 62.1 6.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CCH60229.1 - 3.4e-10 39.8 1.7 3.4e-10 39.8 1.7 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain HypA PF01155.19 CCH60229.1 - 0.089 12.8 3.2 0.24 11.4 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4670 PF15709.5 CCH60229.1 - 1.8 7.8 9.7 2.7 7.2 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) RRM_1 PF00076.22 CCH60230.1 - 2e-19 69.1 0.0 3.5e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CCH60230.1 - 5.5e-08 32.3 0.2 1.3e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 CCH60230.1 - 7.1e-06 26.4 0.4 1.5e-05 25.3 0.4 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_occluded PF16842.5 CCH60230.1 - 0.00096 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CCH60230.1 - 0.15 12.2 0.0 0.57 10.3 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif CSTF2_hinge PF14327.6 CCH60231.1 - 5.5e-24 84.4 2.3 5.5e-24 84.4 2.3 2.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CCH60231.1 - 5.6e-09 35.4 1.3 1.4e-08 34.1 1.3 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 CCH60231.1 - 0.0017 18.1 0.0 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GWT1 PF06423.12 CCH60232.1 - 0.0053 16.9 0.4 0.0058 16.8 0.4 1.2 1 0 0 1 1 1 1 GWT1 DUF4384 PF14326.6 CCH60232.1 - 0.0078 16.3 0.0 0.024 14.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4384) RNase_PH PF01138.21 CCH60233.1 - 1.3e-18 67.8 0.2 1.7e-18 67.4 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RRM_1 PF00076.22 CCH60234.1 - 3.7e-44 148.4 0.0 3.3e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH60234.1 - 0.00014 21.9 0.0 0.065 13.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CCH60234.1 - 0.0082 15.7 0.0 0.38 10.3 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 CCH60234.1 - 0.012 15.6 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 CCH60234.1 - 0.025 14.6 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MIF4G PF02854.19 CCH60236.1 - 6.6e-44 150.1 0.0 6.6e-44 150.1 0.0 2.4 3 0 0 3 3 3 1 MIF4G domain eIF_4G1 PF12152.8 CCH60236.1 - 1.6e-22 79.5 0.1 6.5e-22 77.5 0.1 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Cys_Met_Meta_PP PF01053.20 CCH60237.1 - 2.5e-143 477.3 0.0 2.8e-143 477.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CCH60237.1 - 5.1e-09 35.9 0.0 7.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCH60237.1 - 2.1e-08 33.6 0.1 3.2e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCH60237.1 - 4.1e-08 32.8 0.0 6.5e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCH60237.1 - 2.3e-05 23.8 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CCH60237.1 - 0.0013 17.3 0.0 0.0021 16.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 CCH60237.1 - 0.015 15.5 0.0 0.045 14.0 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 CCH60237.1 - 0.025 13.4 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CPSase_L_D2 PF02786.17 CCH60237.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain TSNAXIP1_N PF15739.5 CCH60238.1 - 0.05 14.0 3.6 2.1 8.8 0.1 3.7 3 1 2 5 5 5 0 Translin-associated factor X-interacting N-terminus FlxA PF14282.6 CCH60238.1 - 0.074 13.0 5.3 0.19 11.8 5.3 1.6 1 0 0 1 1 1 0 FlxA-like protein Swi5 PF07061.11 CCH60238.1 - 2.3 8.3 5.1 0.59 10.3 1.2 2.1 2 0 0 2 2 2 0 Swi5 CBF PF03914.17 CCH60239.1 - 2.4e-33 115.6 2.1 4.4e-33 114.7 0.1 2.3 2 0 0 2 2 2 1 CBF/Mak21 family Asn_synthase PF00733.21 CCH60240.1 - 5.4e-94 315.8 1.1 2e-55 188.9 0.1 2.3 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCH60240.1 - 5.8e-34 116.6 0.0 9.3e-34 116.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCH60240.1 - 5.7e-28 97.8 0.0 1.2e-27 96.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCH60240.1 - 3.8e-08 33.0 0.0 8.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein QueC PF06508.13 CCH60240.1 - 0.0061 16.1 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 CCH60240.1 - 0.04 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Sulfate_transp PF00916.20 CCH60241.1 - 2.7e-76 256.8 27.1 4.1e-76 256.2 27.1 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCH60241.1 - 2.4e-14 53.0 1.5 4.3e-14 52.1 1.5 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 CCH60241.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain MFS_MOT1 PF16983.5 CCH60241.1 - 1.3 9.5 17.5 0.17 12.3 3.3 3.1 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily LIDHydrolase PF10230.9 CCH60242.1 - 1.5e-69 234.5 0.1 1.7e-69 234.3 0.1 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1057 PF06342.12 CCH60242.1 - 1.6e-05 24.1 1.8 0.012 14.6 1.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 CCH60242.1 - 0.0059 16.3 2.1 0.0068 16.2 0.7 1.8 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 CCH60242.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 CCH60242.1 - 0.054 12.6 0.4 0.74 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 CCH60242.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2235 PF09994.9 CCH60242.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_6 PF12697.7 CCH60242.1 - 0.085 13.4 0.0 0.097 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Utp8 PF10395.9 CCH60243.1 - 1.1e-219 731.5 32.4 1.3e-219 731.3 32.4 1.1 1 0 0 1 1 1 1 Utp8 family Gp-FAR-1 PF05823.12 CCH60244.1 - 0.0098 16.3 1.2 0.0098 16.3 1.2 2.5 1 1 2 3 3 3 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DCD PF06559.11 CCH60245.1 - 0.0076 15.1 1.5 0.014 14.2 1.5 1.4 1 0 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Jnk-SapK_ap_N PF09744.9 CCH60245.1 - 9.3 6.5 25.8 1.4 9.2 0.3 4.5 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 MARVEL PF01284.23 CCH60246.1 - 1.7e-25 89.8 6.7 2e-25 89.5 6.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain UQ_con PF00179.26 CCH60247.1 - 7.5e-36 122.9 0.9 8.5e-36 122.7 0.9 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCH60247.1 - 0.0037 17.0 0.1 0.0047 16.6 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CCH60247.1 - 0.0057 16.9 2.3 0.0079 16.5 2.3 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 CCH60247.1 - 0.014 15.2 0.6 0.021 14.7 0.6 1.3 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.11 CCH60247.1 - 0.094 12.4 0.1 0.19 11.4 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 CNOT11 PF10155.9 CCH60248.1 - 0.037 14.2 0.7 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Tmemb_170 PF10190.9 CCH60249.1 - 1.5e-13 51.0 10.5 1.7e-13 50.8 10.5 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 SH3_1 PF00018.28 CCH60250.1 - 2.5e-13 49.4 0.0 4.8e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH60250.1 - 2.9e-12 46.2 0.0 5.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH60250.1 - 9.9e-09 34.8 0.0 1.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF910 PF06014.11 CCH60250.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) Pex14_N PF04695.13 CCH60250.1 - 0.82 10.3 14.4 0.37 11.4 10.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Vps62 PF06101.11 CCH60251.1 - 6.6e-06 24.7 1.4 1.1e-05 24.0 0.8 1.6 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 HCMVantigenic_N PF12154.8 CCH60251.1 - 0.11 12.6 0.6 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV TFIIA PF03153.13 CCH60252.1 - 4.7 7.1 32.0 6.3 6.7 32.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKN1 PF03935.15 CCH60253.1 - 3.6e-248 824.0 5.2 3.6e-248 824.0 5.2 1.9 2 0 0 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) DUF1438 PF07270.11 CCH60253.1 - 0.041 14.0 2.7 3.9 7.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1438) DUF1772 PF08592.11 CCH60253.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) ANAPC4 PF12896.7 CCH60254.1 - 1.1e-28 100.1 2.6 2.4e-28 99.1 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 PHD PF00628.29 CCH60255.1 - 0.0037 17.1 2.5 0.013 15.4 2.5 1.9 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.25 CCH60256.1 - 4.2e-69 232.9 2.1 8e-67 225.4 2.1 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60256.1 - 2.1e-41 141.9 0.4 3.8e-40 137.8 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CCH60256.1 - 6.2e-18 64.3 0.0 1.1e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CCH60256.1 - 4.7e-08 32.7 0.0 9.7e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCH60256.1 - 4.5e-05 22.9 0.2 0.00011 21.7 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCH60256.1 - 0.0028 16.5 0.0 0.0028 16.5 0.0 3.4 4 0 0 4 4 4 1 Fungal protein kinase APH PF01636.23 CCH60256.1 - 0.0037 17.2 0.0 0.031 14.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCH60256.1 - 0.0049 15.9 2.9 0.0085 15.1 0.1 2.5 2 0 0 2 2 2 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CCH60256.1 - 0.11 12.1 2.0 0.22 11.0 0.1 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Transp_cyt_pur PF02133.15 CCH60258.1 - 1.2e-85 287.9 35.9 1.5e-85 287.6 35.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.26 CCH60259.1 - 2.4e-53 181.3 0.0 3.3e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CCH60259.1 - 2.6e-26 92.0 0.1 4.6e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Vhr1 PF04001.13 CCH60261.1 - 1.1e-45 153.8 2.6 3.2e-45 152.4 2.6 1.8 1 0 0 1 1 1 1 Transcription factor Vhr1 DUF4175 PF13779.6 CCH60261.1 - 0.56 8.0 35.0 1.1 7.1 35.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ICL PF00463.21 CCH60262.1 - 1.2e-261 868.8 2.7 1.4e-261 868.6 2.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCH60262.1 - 1.8e-09 37.4 0.3 4.1e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2663 PF10864.8 CCH60262.1 - 0.21 12.0 2.1 5.5 7.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) RGI1 PF10843.8 CCH60263.1 - 2.9e-34 118.4 7.9 3.8e-34 118.0 7.9 1.1 1 0 0 1 1 1 1 Respiratory growth induced protein 1 DUF3035 PF11233.8 CCH60263.1 - 0.16 12.2 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) U1snRNP70_N PF12220.8 CCH60264.1 - 4.1e-24 85.0 1.1 4.1e-24 85.0 1.1 2.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CCH60264.1 - 1.2e-13 50.7 0.8 1.3e-11 44.1 0.8 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH60264.1 - 1.5e-09 37.8 0.0 3.6e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif NAT PF04768.13 CCH60265.1 - 3.3e-55 186.4 0.5 7.2e-55 185.2 0.2 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 CCH60265.1 - 1.4e-30 106.3 0.0 3.5e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 CCH60265.1 - 4.5e-25 88.7 0.1 8.5e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 CCH60265.1 - 9.6e-11 42.1 0.0 2.1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 CCH60265.1 - 0.0071 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 40S_S4_C PF16121.5 CCH60265.1 - 0.13 11.9 0.1 0.42 10.3 0.1 1.9 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus P16-Arc PF04699.14 CCH60266.1 - 1.5e-45 155.3 0.0 1.6e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Sigma70_r4_2 PF08281.12 CCH60266.1 - 0.0087 15.7 0.0 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 Utp12 PF04003.12 CCH60266.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family Sigma70_r4 PF04545.16 CCH60266.1 - 0.18 11.3 0.0 0.39 10.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-70, region 4 Ran_BP1 PF00638.18 CCH60267.1 - 4.9e-35 120.5 0.8 4.9e-35 120.5 0.8 2.2 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.23 CCH60267.1 - 4.9e-05 23.2 0.0 9.9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 WH1 domain Methyltransf_31 PF13847.6 CCH60268.1 - 1.7e-27 96.1 0.0 2.8e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH60268.1 - 2.8e-09 37.6 0.0 6.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH60268.1 - 1.5e-08 35.2 0.0 2.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH60268.1 - 9.8e-08 32.5 0.0 1.5e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH60268.1 - 2.6e-05 24.1 0.0 3.8e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH60268.1 - 0.00026 20.4 0.0 0.00031 20.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CCH60268.1 - 0.00032 20.7 0.0 0.00044 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCH60268.1 - 0.0004 20.0 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CCH60268.1 - 0.0051 16.2 0.1 0.0072 15.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 CCH60268.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 CCH60268.1 - 0.024 14.1 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 CCH60268.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CCH60268.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 CCH60268.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Fis1_TPR_C PF14853.6 CCH60269.1 - 2.3e-21 75.6 0.7 3.8e-21 74.9 0.7 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CCH60269.1 - 2.1e-16 59.3 0.0 3.5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CCH60269.1 - 0.00026 20.8 1.2 0.0006 19.7 0.7 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH60269.1 - 0.029 15.2 0.2 0.088 13.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.15 CCH60270.1 - 1.3e-184 614.6 0.0 1.8e-184 614.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCH60270.1 - 7.7e-25 86.7 0.1 2.1e-24 85.3 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCH60270.1 - 4.9e-16 59.1 0.0 1.4e-15 57.6 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Sec6 PF06046.13 CCH60271.1 - 5.4e-173 576.4 15.4 8.1e-173 575.9 15.4 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF489 PF04356.12 CCH60271.1 - 2.1 8.3 5.9 0.94 9.5 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Tctex-1 PF03645.13 CCH60272.1 - 1.7e-08 34.6 0.1 2e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family CooC_C PF15976.5 CCH60272.1 - 0.019 15.0 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 CS1-pili formation C-terminal DUF202 PF02656.15 CCH60273.1 - 2.6e-15 56.6 5.5 3e-15 56.4 3.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ribosomal_S24e PF01282.19 CCH60274.1 - 6.8e-34 115.7 0.1 1.1e-33 115.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Y_phosphatase PF00102.27 CCH60275.1 - 3.5e-42 144.6 6.2 1.3e-35 123.0 1.7 3.2 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 CCH60275.1 - 2.1e-07 31.4 0.0 4e-06 27.3 0.0 2.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 CCH60275.1 - 0.027 14.3 0.1 0.027 14.3 0.1 4.0 4 0 0 4 4 4 0 Dual specificity phosphatase, catalytic domain AvrPtoB_bdg PF16847.5 CCH60275.1 - 0.099 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain DHBP_synthase PF00926.19 CCH60275.1 - 0.26 10.8 0.9 9.3 5.7 0.6 2.4 2 0 0 2 2 2 0 3,4-dihydroxy-2-butanone 4-phosphate synthase MAM33 PF02330.16 CCH60276.1 - 1.7e-57 194.8 12.8 2e-57 194.6 12.8 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein PPR_2 PF13041.6 CCH60277.1 - 2.4e-12 46.9 4.3 1e-09 38.4 0.0 4.0 5 0 0 5 5 5 2 PPR repeat family PCI PF01399.27 CCH60278.1 - 0.002 18.6 2.5 0.0071 16.8 0.1 2.8 2 1 0 2 2 2 1 PCI domain HTH_Tnp_Mu_1 PF02316.16 CCH60278.1 - 0.21 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain HIT PF01230.23 CCH60279.1 - 3.1e-25 88.8 0.2 4.5e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCH60279.1 - 8.5e-12 45.6 0.2 1.1e-11 45.1 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CCH60279.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AAA PF00004.29 CCH60280.1 - 3.2e-99 328.5 0.0 2.7e-48 163.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH60280.1 - 5.2e-26 90.2 6.4 2.3e-13 49.7 1.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CCH60280.1 - 2.9e-17 62.6 0.1 7.5e-17 61.3 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 CCH60280.1 - 1.2e-14 55.1 0.0 8.6e-05 23.0 0.1 4.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CCH60280.1 - 1.3e-14 54.7 0.3 7.2e-07 29.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCH60280.1 - 9.1e-14 51.5 0.0 2e-05 24.4 0.0 3.0 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CCH60280.1 - 5.7e-11 42.8 0.0 3.3e-05 24.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CCH60280.1 - 5.9e-11 42.5 0.9 1.5e-05 25.1 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CCH60280.1 - 1.5e-09 37.5 2.7 0.0013 18.0 0.0 3.3 3 0 0 3 3 3 2 TIP49 P-loop domain CDC48_2 PF02933.17 CCH60280.1 - 5e-09 35.8 0.0 1.6e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CCH60280.1 - 7e-09 36.1 3.9 0.027 14.7 0.0 4.4 3 2 2 5 5 4 2 AAA domain AAA_14 PF13173.6 CCH60280.1 - 3.7e-08 33.5 0.0 0.0062 16.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 CCH60280.1 - 1.1e-07 32.2 0.0 0.0098 16.3 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 CCH60280.1 - 2.1e-07 31.5 0.3 0.049 14.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain ATPase PF06745.13 CCH60280.1 - 2.3e-07 30.4 1.1 0.088 12.1 0.1 3.8 2 1 1 3 3 3 2 KaiC IstB_IS21 PF01695.17 CCH60280.1 - 5e-07 29.6 0.1 0.031 14.0 0.0 3.0 4 0 0 4 4 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCH60280.1 - 1.4e-06 27.8 0.2 0.027 13.9 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCH60280.1 - 2.2e-06 27.5 0.7 0.023 14.4 0.0 3.2 3 1 0 3 3 2 2 AAA domain Vps4_C PF09336.10 CCH60280.1 - 3e-06 27.2 2.0 7.3e-05 22.7 0.2 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 CCH60280.1 - 7.4e-06 25.8 0.1 0.077 12.7 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 CCH60280.1 - 1.2e-05 25.6 0.1 0.22 11.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CCH60280.1 - 1.3e-05 24.8 0.1 0.087 12.3 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 CCH60280.1 - 1.4e-05 24.8 9.0 0.58 9.7 0.1 4.5 2 2 2 4 4 4 1 AAA domain Bac_DnaA PF00308.18 CCH60280.1 - 1.6e-05 24.8 0.0 0.026 14.4 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 CCH60280.1 - 3.4e-05 23.1 0.1 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 CCH60280.1 - 4.8e-05 22.9 0.5 0.19 11.1 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 CCH60280.1 - 7.2e-05 23.3 3.0 0.092 13.3 0.0 4.2 5 1 0 5 5 2 1 ABC transporter ResIII PF04851.15 CCH60280.1 - 7.3e-05 22.8 0.3 0.032 14.3 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CCH60280.1 - 9.8e-05 21.7 0.5 0.2 10.8 0.0 2.7 3 0 0 3 3 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 CCH60280.1 - 0.00012 22.0 0.0 0.62 9.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CCH60280.1 - 0.00025 21.5 1.6 0.58 10.6 0.0 3.4 3 1 0 3 3 2 2 AAA domain DUF815 PF05673.13 CCH60280.1 - 0.00028 20.1 0.0 0.18 10.9 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 CCH60280.1 - 0.00041 20.3 0.2 2.3 8.1 0.0 3.5 4 0 0 4 4 3 1 NACHT domain TsaE PF02367.17 CCH60280.1 - 0.00056 19.9 0.0 0.67 10.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CCH60280.1 - 0.00076 19.2 0.4 1.2 8.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCH60280.1 - 0.0012 19.1 1.4 2.6 8.4 0.0 3.2 2 2 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 CCH60280.1 - 0.003 17.7 0.0 0.31 11.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IPT PF01745.16 CCH60280.1 - 0.0048 16.3 0.1 0.6 9.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase ATPase_2 PF01637.18 CCH60280.1 - 0.0068 16.3 5.9 0.33 10.8 0.1 4.0 3 2 0 3 3 2 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CCH60280.1 - 0.012 15.5 1.1 8.5 6.3 0.0 4.1 4 0 0 4 4 4 0 NTPase NB-ARC PF00931.22 CCH60280.1 - 0.012 14.8 0.0 5.5 6.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin PF02224.18 CCH60280.1 - 0.025 14.3 0.1 7.7 6.2 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 CCH60280.1 - 0.032 13.5 0.5 2.2 7.5 0.0 3.2 2 2 1 4 4 4 0 KAP family P-loop domain Zeta_toxin PF06414.12 CCH60280.1 - 0.035 13.4 0.2 15 4.8 0.0 3.3 4 0 0 4 4 3 0 Zeta toxin eIF-1a PF01176.19 CCH60280.1 - 0.042 13.7 0.1 0.41 10.5 0.0 2.5 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 AAA_11 PF13086.6 CCH60280.1 - 0.052 13.3 13.0 0.43 10.3 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_6 PF12774.7 CCH60280.1 - 0.073 12.0 0.3 4.2 6.3 0.0 2.7 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 CCH60280.1 - 0.15 11.8 0.0 26 4.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 CCH60280.1 - 0.17 11.6 0.1 19 4.9 0.0 2.9 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase Zot PF05707.12 CCH60280.1 - 0.25 10.9 2.5 3.7 7.1 0.0 3.3 3 2 0 3 3 2 0 Zonular occludens toxin (Zot) FKBP_N PF01346.18 CCH60280.1 - 0.36 11.8 6.6 0.14 13.1 1.4 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Hydin_ADK PF17213.3 CCH60280.1 - 2.2 8.5 5.7 51 4.1 0.0 4.0 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Cyclin_N PF00134.23 CCH60281.1 - 5.3e-17 61.8 0.1 9.4e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCH60281.1 - 2.4e-06 28.0 0.0 2.4e-06 28.0 0.0 2.6 2 1 0 2 2 2 1 Cyclin CDP-OH_P_transf PF01066.21 CCH60282.1 - 1.4e-10 41.8 0.3 1.4e-10 41.8 0.3 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Clathrin PF00637.20 CCH60283.1 - 7.6e-186 609.4 56.9 1.4e-33 115.8 0.1 9.0 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CCH60283.1 - 1.1e-26 92.5 0.4 4.3e-26 90.6 0.1 2.3 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 CCH60283.1 - 5.2e-24 83.3 6.7 1.6e-05 25.0 0.1 5.7 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.10 CCH60283.1 - 1.7e-07 30.5 0.0 1.7e-07 30.5 0.0 2.8 4 0 0 4 4 4 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CCH60283.1 - 0.00011 21.3 12.4 0.089 11.8 0.1 5.6 5 1 1 6 6 6 2 Coatomer WD associated region Bystin PF05291.11 CCH60283.1 - 0.0018 17.6 0.7 0.41 9.9 0.1 2.9 2 0 0 2 2 2 2 Bystin TPR_19 PF14559.6 CCH60283.1 - 0.66 10.5 3.4 20 5.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCH60283.1 - 0.72 10.0 2.9 72 3.8 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCH60283.1 - 4.2 7.3 5.9 21 5.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 CCH60284.1 - 1.7e-06 28.2 16.4 0.0011 19.2 2.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH60284.1 - 3.1e-05 24.2 17.3 0.00022 21.5 5.7 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH60284.1 - 7.5e-05 23.3 13.8 0.062 14.2 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH60284.1 - 0.017 15.4 7.4 0.062 13.6 2.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CCH60284.1 - 0.023 15.3 0.1 0.065 13.9 0.1 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain Pox_Ag35 PF03286.14 CCH60284.1 - 0.072 12.9 4.4 0.15 11.9 0.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein zf-H2C2_5 PF13909.6 CCH60284.1 - 0.19 11.5 9.2 0.53 10.1 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 CCH60284.1 - 0.94 9.6 7.9 7 6.8 0.0 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger RHINO PF15319.6 CCH60284.1 - 1.4 8.9 15.6 0.029 14.4 6.9 2.0 2 0 0 2 2 2 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein LSM PF01423.22 CCH60285.1 - 4.6e-19 67.9 0.9 9.1e-19 66.9 0.9 1.5 1 0 0 1 1 1 1 LSM domain Presenilin PF01080.17 CCH60285.1 - 2.7 6.6 4.7 3.3 6.4 4.7 1.1 1 0 0 1 1 1 0 Presenilin YfhO PF09586.10 CCH60285.1 - 5.1 5.2 8.0 5.6 5.1 8.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CHZ PF09649.10 CCH60286.1 - 2.7e-16 58.7 1.1 2.7e-16 58.7 1.1 2.5 3 0 0 3 3 3 1 Histone chaperone domain CHZ Spc42p PF11544.8 CCH60286.1 - 0.00011 22.1 2.8 0.00011 22.1 2.8 2.3 2 1 0 2 2 2 1 Spindle pole body component Spc42p Ras PF00071.22 CCH60287.1 - 8.5e-61 204.3 0.1 1e-60 204.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH60287.1 - 2e-33 115.2 0.2 3.6e-33 114.3 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH60287.1 - 5.7e-13 48.7 0.0 7.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCH60287.1 - 2.4e-06 27.6 0.0 4.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH60287.1 - 0.0018 17.9 0.1 0.0071 15.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 CCH60287.1 - 0.0027 17.0 0.1 0.0053 16.1 0.1 1.4 1 1 0 1 1 1 1 KAP family P-loop domain RsgA_GTPase PF03193.16 CCH60287.1 - 0.0029 17.6 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CCH60287.1 - 0.0041 16.5 0.0 0.006 16.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CCH60287.1 - 0.0058 16.4 0.0 0.0099 15.6 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CCH60287.1 - 0.012 15.1 0.1 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CCH60287.1 - 0.017 15.5 0.1 0.034 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CCH60287.1 - 0.029 14.1 0.1 0.064 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CCH60287.1 - 0.035 14.4 0.1 0.063 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CCH60287.1 - 0.039 13.2 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CCH60287.1 - 0.06 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 CCH60287.1 - 0.086 12.7 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 FeoB_N PF02421.18 CCH60287.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1128 PF06569.11 CCH60287.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) SLS PF14611.6 CCH60287.1 - 0.12 12.1 2.7 0.22 11.3 2.7 1.6 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator ABC_tran PF00005.27 CCH60287.1 - 0.15 12.6 2.6 0.37 11.3 2.5 1.9 1 1 0 1 1 1 0 ABC transporter ATP_bind_3 PF01171.20 CCH60290.1 - 3.5e-19 69.3 0.2 8.8e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 CCH60290.1 - 4.8e-18 64.3 3.8 4.8e-18 64.3 3.8 3.2 3 0 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CCH60290.1 - 0.00045 19.1 0.8 0.0011 17.9 0.1 1.9 2 1 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.14 CCH60290.1 - 0.044 13.4 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 CCH60290.1 - 0.083 12.0 0.2 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD synthase TF_Zn_Ribbon PF08271.12 CCH60290.1 - 0.87 9.1 8.4 1.1 8.8 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding Ribosomal_S14 PF00253.21 CCH60290.1 - 2.7 7.8 9.4 1.2 9.0 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e Cyclin PF08613.11 CCH60291.1 - 0.00046 20.6 0.0 0.00046 20.6 0.0 2.7 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 CCH60291.1 - 0.021 14.6 0.0 0.069 12.9 0.0 1.9 1 1 0 1 1 1 0 Cyclin, N-terminal domain EHN PF06441.12 CCH60291.1 - 0.11 12.9 0.3 0.26 11.7 0.3 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Kinesin PF00225.23 CCH60292.1 - 8e-114 380.0 6.9 1.8e-113 378.8 6.9 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCH60292.1 - 8.6e-26 90.7 0.2 8.6e-26 90.7 0.2 3.1 3 1 0 3 3 3 1 Microtubule binding AAA_33 PF13671.6 CCH60292.1 - 0.044 14.0 0.0 0.57 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain BolA PF01722.18 CCH60293.1 - 1.6e-15 57.2 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Hydantoinase_B PF02538.14 CCH60293.1 - 0.15 10.4 0.1 0.19 10.1 0.1 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase NIF3 PF01784.18 CCH60294.1 - 8.9e-63 212.2 0.0 1.1e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) HMA PF00403.26 CCH60296.1 - 0.019 15.4 0.3 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain DUF5442 PF17514.2 CCH60296.1 - 0.43 10.8 4.7 0.38 11.0 1.9 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5442) WD40 PF00400.32 CCH60297.1 - 1.3e-05 25.8 8.9 0.068 14.1 0.3 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 CCH60297.1 - 0.00059 18.6 2.6 0.0023 16.6 1.7 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCH60297.1 - 0.049 13.9 0.3 2.8 8.3 0.2 3.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CCH60297.1 - 0.091 13.3 0.2 0.99 10.0 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain NMT_C PF02799.15 CCH60298.1 - 1.4e-79 266.5 0.5 2.6e-79 265.6 0.5 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CCH60298.1 - 2.9e-74 248.2 1.1 4.9e-74 247.5 0.1 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 CCH60298.1 - 4.8e-06 26.7 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCH60298.1 - 0.034 14.8 0.0 0.52 11.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCH60298.1 - 0.034 14.4 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4731 PF15875.5 CCH60299.1 - 0.78 10.0 2.3 2.3 8.5 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4731) DUF3602 PF12223.8 CCH60300.1 - 4.9e-18 65.5 4.5 1.4e-08 35.2 0.0 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) eIF3_subunit PF08597.10 CCH60301.1 - 1.5e-46 159.3 16.8 1.8e-46 159.0 16.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Vps62 PF06101.11 CCH60301.1 - 0.033 12.5 0.0 0.046 12.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 BDHCT_assoc PF16204.5 CCH60301.1 - 3.6 7.2 7.4 0.41 10.3 0.9 2.3 2 1 1 3 3 3 0 BDHCT-box associated domain on Bloom syndrome protein G_glu_transpept PF01019.21 CCH60302.1 - 0.064 12.0 1.7 0.085 11.6 1.7 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase PALP PF00291.25 CCH60303.1 - 1.2e-76 257.9 0.1 1.6e-76 257.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CCH60303.1 - 1.3e-37 127.4 0.1 2.1e-24 85.1 0.0 3.3 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF4404 PF14357.6 CCH60303.1 - 0.29 11.8 1.9 0.34 11.6 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) tRNA-synt_2b PF00587.25 CCH60304.1 - 4e-35 121.4 0.1 7e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCH60304.1 - 0.013 15.6 0.2 0.028 14.6 0.2 1.6 1 0 0 1 1 1 0 Anticodon binding domain Sec61_beta PF03911.16 CCH60305.1 - 2.9e-14 52.8 2.8 3.6e-14 52.5 2.8 1.1 1 0 0 1 1 1 1 Sec61beta family Tir_receptor_N PF07490.11 CCH60305.1 - 0.032 14.0 0.0 0.035 13.9 0.0 1.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus MOZ_SAS PF01853.18 CCH60306.1 - 5.8e-70 234.6 0.0 8e-70 234.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCH60306.1 - 4.4e-15 55.0 0.3 9.4e-15 54.0 0.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCH60306.1 - 0.0014 19.0 0.0 0.0029 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.31 CCH60307.1 - 2.3e-12 46.9 2.0 1.9e-09 37.5 0.5 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH60307.1 - 2.4e-08 34.1 1.9 1.3e-07 31.7 0.7 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain TatD_DNase PF01026.21 CCH60308.1 - 2e-37 129.0 0.0 2.9e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Fanconi_A_N PF15865.5 CCH60308.1 - 0.002 17.6 0.6 0.0044 16.5 0.2 1.6 2 0 0 2 2 2 1 Fanconi anaemia group A protein N terminus TatD_DNase PF01026.21 CCH60309.1 - 1.6e-29 103.0 0.0 1.4e-28 100.0 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase PP2C PF00481.21 CCH60310.1 - 3.9e-78 262.7 0.1 6e-78 262.0 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PhageMin_Tail PF10145.9 CCH60310.1 - 0.055 13.3 0.0 1 9.2 0.0 2.2 1 1 0 2 2 2 0 Phage-related minor tail protein SEP PF08059.13 CCH60311.1 - 2.8e-21 75.9 2.3 3e-21 75.8 0.2 2.3 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 CCH60311.1 - 2.2e-16 59.8 0.1 4.4e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CCH60311.1 - 5e-05 23.0 0.4 0.00012 21.8 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain IES5 PF17335.2 CCH60312.1 - 2.3e-24 85.8 11.2 3.4e-13 49.8 3.7 2.1 1 1 1 2 2 2 2 Ino80 complex subunit 5 DUF2935 PF11155.8 CCH60312.1 - 0.11 12.8 1.4 0.16 12.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) RICTOR_N PF14664.6 CCH60313.1 - 2.3e-90 303.3 20.9 2.3e-90 303.3 20.9 2.1 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CCH60313.1 - 4.9e-30 103.4 0.0 4.9e-30 103.4 0.0 4.3 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CCH60313.1 - 4.8e-28 97.2 2.7 5.8e-27 93.7 0.2 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CCH60313.1 - 7.8e-27 93.8 2.9 3.5e-26 91.7 0.3 3.6 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain UPF0242 PF06785.11 CCH60313.1 - 9.5 6.3 28.8 0.11 12.6 8.2 3.7 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF2721 PF11026.8 CCH60314.1 - 0.0081 16.0 1.1 2.6 8.0 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2721) DUF758 PF05527.11 CCH60314.1 - 0.031 14.3 1.1 1.5 8.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF758) Sel1 PF08238.12 CCH60315.1 - 3.6e-46 154.6 18.3 9.5e-08 32.5 1.6 7.4 7 0 0 7 7 7 7 Sel1 repeat PLDc_2 PF13091.6 CCH60315.1 - 0.074 12.9 0.2 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 PLD-like domain Sel1 PF08238.12 CCH60316.1 - 4.8e-44 147.8 14.0 2.4e-07 31.2 1.1 7.4 7 0 0 7 7 7 7 Sel1 repeat GFD1 PF17331.2 CCH60317.1 - 1.3e-07 31.6 20.2 1.2e-06 28.5 12.4 2.8 2 0 0 2 2 2 2 GFD1 mRNA transport factor GA PF01468.17 CCH60317.1 - 0.045 14.0 2.1 0.091 13.1 1.3 2.0 1 1 0 1 1 1 0 GA module Snapin_Pallidin PF14712.6 CCH60317.1 - 0.075 13.5 5.6 2.3 8.7 1.3 2.6 1 1 1 2 2 2 0 Snapin/Pallidin ApbA PF02558.16 CCH60318.1 - 1.7e-29 102.4 0.0 2.5e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CCH60318.1 - 1.8e-23 83.1 0.0 2.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Citrate_synt PF00285.21 CCH60319.1 - 1.4e-91 307.3 0.0 1.7e-91 307.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Prefoldin_3 PF13758.6 CCH60319.1 - 0.12 12.4 0.0 0.9 9.6 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1921 PF09081.10 CCH60319.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) Urease_alpha PF00449.20 CCH60319.1 - 0.21 11.9 0.5 0.5 10.7 0.5 1.6 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain MmgE_PrpD PF03972.14 CCH60320.1 - 3.3e-146 487.3 0.0 4.1e-146 487.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nic96 PF04097.14 CCH60321.1 - 1.6e-159 532.3 7.5 2.5e-159 531.6 7.5 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Peptidase_M24 PF00557.24 CCH60322.1 - 4.6e-58 196.4 0.0 5.9e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCH60322.1 - 7.9e-22 77.3 0.0 2.8e-21 75.5 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 CCH60322.1 - 0.029 14.4 0.2 0.068 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Sulfate_transp PF00916.20 CCH60323.1 - 6.9e-87 291.7 21.1 9.3e-87 291.2 21.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCH60323.1 - 1.4e-14 53.7 0.0 3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CCH60323.1 - 0.0054 17.1 6.7 0.0054 17.1 6.7 2.6 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily Mpp10 PF04006.12 CCH60324.1 - 0.0034 15.9 19.5 0.0038 15.7 19.5 1.1 1 0 0 1 1 1 1 Mpp10 protein Astro_capsid_p PF12226.8 CCH60324.1 - 0.0034 16.6 20.0 0.0047 16.1 20.0 1.3 1 0 0 1 1 1 1 Turkey astrovirus capsid protein SDA1 PF05285.12 CCH60324.1 - 0.0099 15.3 22.1 0.011 15.1 22.1 1.2 1 0 0 1 1 1 1 SDA1 SAPS PF04499.15 CCH60324.1 - 4.2 6.0 10.7 4.4 6.0 10.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Roughex PF06020.11 CCH60324.1 - 5.3 6.0 12.8 6.8 5.7 12.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Trypan_PARP PF05887.11 CCH60324.1 - 7 6.6 20.7 9.9 6.1 20.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rad21_Rec8_N PF04825.13 CCH60325.1 - 2.8e-14 53.2 0.1 9.3e-14 51.5 0.1 1.9 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Noggin PF05806.12 CCH60325.1 - 0.028 14.3 0.2 6.2 6.7 0.0 2.7 2 0 0 2 2 2 0 Noggin Rrp15p PF07890.12 CCH60326.1 - 3.5e-28 98.6 11.6 3.5e-28 98.6 11.6 2.6 2 1 0 2 2 2 1 Rrp15p Glyco_hydro_63 PF03200.16 CCH60326.1 - 0.0014 17.4 0.6 0.0019 17.0 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain PAS_2 PF08446.11 CCH60326.1 - 0.16 12.7 0.3 0.43 11.3 0.3 1.8 1 1 0 1 1 1 0 PAS fold Kinesin PF00225.23 CCH60327.1 - 3.1e-99 332.1 5.5 6.3e-99 331.1 5.5 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCH60327.1 - 2.5e-48 163.8 0.0 2.5e-48 163.8 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding Acyltransferase PF01553.21 CCH60328.1 - 3.5e-16 59.1 0.0 6.4e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase VF530 PF09905.9 CCH60329.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 DNA-binding protein VF530 Acyltransferase PF01553.21 CCH60329.1 - 0.096 12.3 0.0 0.43 10.2 0.0 1.9 1 1 0 1 1 1 0 Acyltransferase DUF5355 PF17306.2 CCH60330.1 - 5.4e-97 324.8 15.8 9.2e-97 324.0 15.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5355) WD40 PF00400.32 CCH60331.1 - 2.5e-16 59.8 2.9 4.6e-05 24.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 CCH60331.1 - 0.0073 15.7 1.8 0.15 11.4 0.0 3.3 4 0 0 4 4 4 1 WD40-like domain ANAPC4_WD40 PF12894.7 CCH60331.1 - 0.015 15.6 0.0 0.2 12.0 0.0 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2452 PF10504.9 CCH60331.1 - 0.038 13.4 0.4 0.076 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Cytochrom_D1 PF02239.16 CCH60331.1 - 0.044 12.3 0.0 0.18 10.3 0.0 1.9 1 1 0 1 1 1 0 Cytochrome D1 heme domain PGA2 PF07543.12 CCH60331.1 - 5.7 6.9 11.3 11 6.0 11.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Mcl1_mid PF12341.8 CCH60332.1 - 2.5e-83 279.8 0.0 8e-83 278.2 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CCH60332.1 - 3.5e-06 27.2 0.1 0.17 12.2 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain COG2 PF06148.11 CCH60333.1 - 5e-07 29.9 3.7 1.4e-06 28.4 3.7 1.8 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 CCH60333.1 - 0.004 17.1 4.3 0.009 15.9 0.3 3.0 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain Med25_VWA PF11265.8 CCH60333.1 - 0.05 13.4 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A RRF PF01765.19 CCH60333.1 - 0.13 12.2 2.1 2.7 7.9 0.0 2.9 2 1 1 3 3 3 0 Ribosome recycling factor PilJ PF13675.6 CCH60333.1 - 0.25 11.4 1.3 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CopG_antitoxin PF12441.8 CCH60333.1 - 0.3 11.6 3.2 0.77 10.3 0.5 2.5 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system Cor1 PF04803.12 CCH60333.1 - 3.1 8.0 6.8 0.66 10.2 0.5 2.7 3 1 0 3 3 3 0 Cor1/Xlr/Xmr conserved region Tom5 PF10642.9 CCH60334.1 - 3.3e-19 68.6 0.4 3.6e-19 68.5 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DUF4267 PF14087.6 CCH60334.1 - 0.062 13.4 0.0 0.062 13.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) Med26 PF08711.11 CCH60335.1 - 2.4e-11 43.5 0.3 1.7e-10 40.7 0.0 2.7 3 0 0 3 3 3 1 TFIIS helical bundle-like domain Phasin PF05597.11 CCH60335.1 - 0.0055 16.7 0.6 0.0055 16.7 0.6 2.3 3 0 0 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Ribosom_S12_S23 PF00164.25 CCH60336.1 - 9.5e-51 170.2 0.3 1.2e-50 169.9 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.25 CCH60337.1 - 4.2e-07 30.2 0.0 5.4e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CCH60337.1 - 4.6e-06 26.5 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CCH60337.1 - 0.00022 21.2 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCH60337.1 - 0.00062 20.1 0.0 0.00092 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCH60337.1 - 0.0038 17.4 0.0 0.0057 16.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Aldo_ket_red PF00248.21 CCH60338.1 - 2.1e-48 165.0 0.0 2.5e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LETM1 PF07766.13 CCH60339.1 - 9.8e-93 310.4 4.5 9.8e-93 310.4 4.5 1.5 2 0 0 2 2 2 1 LETM1-like protein GPAT_N PF14829.6 CCH60339.1 - 0.0038 17.2 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 Glycerol-3-phosphate acyltransferase N-terminal AKNA PF12443.8 CCH60339.1 - 0.024 15.3 4.0 0.058 14.0 4.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Ctr PF04145.15 CCH60340.1 - 2.2e-17 64.0 1.7 2.2e-17 64.0 1.7 2.2 3 0 0 3 3 3 1 Ctr copper transporter family DUF4229 PF14012.6 CCH60340.1 - 0.025 14.7 3.5 0.025 14.7 3.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Tetraspanin PF00335.20 CCH60340.1 - 0.044 13.5 2.6 0.038 13.7 0.9 1.7 2 0 0 2 2 2 0 Tetraspanin family SURF1 PF02104.15 CCH60341.1 - 1.9e-41 142.3 0.1 2.5e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 SURF1 family DUF5634 PF18681.1 CCH60341.1 - 0.00035 20.9 0.0 0.00087 19.6 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5634) Plus-3 PF03126.18 CCH60341.1 - 0.083 13.4 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 Plus-3 domain Acetyltransf_7 PF13508.7 CCH60342.1 - 8.3e-05 22.9 0.1 0.00017 21.9 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCH60342.1 - 0.0031 18.2 0.0 0.0097 16.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCH60342.1 - 0.046 13.8 0.1 0.098 12.7 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCH60342.1 - 0.11 12.4 0.0 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_10 PF13673.7 CCH60342.1 - 0.12 12.3 0.1 0.34 10.9 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M16 PF00675.20 CCH60343.1 - 7.1e-31 107.2 0.2 2.4e-30 105.5 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCH60343.1 - 9.5e-20 71.4 1.7 3.4e-09 37.0 0.1 4.1 4 1 0 4 4 4 3 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 CCH60343.1 - 4.9e-19 68.7 0.9 1.1e-18 67.6 0.9 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 GCP_N_terminal PF17681.1 CCH60344.1 - 1.6e-30 106.8 3.3 3.2e-30 105.8 3.3 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CCH60344.1 - 1.9e-30 106.4 4.9 3.4e-30 105.6 4.9 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal MFS_1 PF07690.16 CCH60345.1 - 2.1e-22 79.6 42.9 2.1e-22 79.6 42.9 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CCH60345.1 - 0.00011 21.1 1.1 0.00011 21.1 1.1 2.7 2 2 0 2 2 2 1 MFS_1 like family SieB PF14163.6 CCH60345.1 - 0.013 15.0 0.1 0.013 15.0 0.1 2.9 4 0 0 4 4 4 0 Super-infection exclusion protein B MFS_1 PF07690.16 CCH60346.1 - 4.1e-23 81.9 36.4 2.1e-22 79.5 37.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Mrpl_C PF18502.1 CCH60346.1 - 0.84 9.9 3.2 0.99 9.7 0.3 2.2 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain ETRAMP PF09716.10 CCH60346.1 - 2.8 8.1 8.4 0.23 11.6 0.4 3.4 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) MutS_V PF00488.21 CCH60347.1 - 4.3e-70 235.6 0.2 7.8e-70 234.7 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCH60347.1 - 2.9e-35 122.2 1.7 7.3e-35 120.9 1.7 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CCH60347.1 - 1.6e-26 92.7 1.5 4.2e-26 91.4 0.1 2.4 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.17 CCH60347.1 - 3.3e-11 43.6 0.1 1.2e-10 41.8 0.1 1.9 1 0 0 1 1 1 1 MutS domain II Peptidase_S78 PF04586.17 CCH60347.1 - 0.012 15.8 0.1 0.16 12.1 0.0 2.8 3 0 0 3 3 3 0 Caudovirus prohead serine protease DUF2585 PF10755.9 CCH60347.1 - 0.035 13.8 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) N-SET PF11764.8 CCH60348.1 - 7.5e-45 153.1 3.2 7.5e-45 153.1 3.2 5.7 5 0 0 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 CCH60348.1 - 1e-16 61.8 0.0 1e-16 61.8 0.0 5.0 4 2 0 4 4 4 1 SET domain SET_assoc PF11767.8 CCH60348.1 - 1.7e-15 56.4 0.0 3.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated ORC6 PF05460.13 CCH60349.1 - 1.1e-71 242.1 12.6 1.6e-70 238.2 12.6 2.0 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF3861 PF12977.7 CCH60349.1 - 0.013 15.7 0.1 0.031 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) PDZ_1 PF12812.7 CCH60350.1 - 2.2e-46 155.7 2.7 3.2e-31 107.2 0.0 3.9 4 0 0 4 4 4 2 PDZ-like domain Trypsin_2 PF13365.6 CCH60350.1 - 7.3e-22 78.9 0.0 5.8e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 CCH60350.1 - 1.1e-12 48.0 0.8 0.00012 22.3 0.0 4.3 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 CCH60350.1 - 1.2e-12 47.9 0.1 1.5e-08 34.8 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CCH60350.1 - 2.9e-11 43.0 0.7 4.8e-06 26.3 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 CCH60350.1 - 0.0024 17.8 0.1 3.7 7.6 0.0 3.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.26 CCH60350.1 - 0.0024 17.7 0.0 0.0071 16.2 0.0 1.7 1 1 0 1 1 1 1 Trypsin DUF31 PF01732.16 CCH60350.1 - 0.014 15.0 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 CCH60350.1 - 0.14 12.0 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease TPR_1 PF00515.28 CCH60351.1 - 2.1e-19 68.4 36.4 1.2e-06 28.1 0.8 9.8 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 CCH60351.1 - 4e-19 67.1 33.7 0.002 18.1 0.0 11.0 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCH60351.1 - 1.1e-13 51.6 3.5 0.0075 16.9 0.0 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH60351.1 - 2.6e-12 45.9 29.7 0.0011 19.0 0.6 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCH60351.1 - 2.9e-11 43.5 15.0 0.047 14.0 0.0 7.4 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCH60351.1 - 5.4e-11 42.4 6.6 2.7 9.0 0.0 8.3 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH60351.1 - 2.6e-10 39.8 15.1 0.0063 16.2 0.3 6.8 5 2 2 7 7 7 3 TPR repeat TPR_19 PF14559.6 CCH60351.1 - 1.9e-09 37.9 15.9 0.0065 16.9 1.8 6.6 4 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH60351.1 - 8.6e-08 32.0 10.6 0.087 13.2 1.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CCH60351.1 - 1.5e-05 24.6 0.2 0.043 13.5 0.5 3.4 3 1 1 4 4 4 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 CCH60351.1 - 2.2e-05 24.5 0.8 0.085 13.0 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCH60351.1 - 0.0001 22.1 10.5 0.92 9.7 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 CCH60351.1 - 0.0004 20.1 10.9 0.17 11.6 0.4 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 CCH60351.1 - 0.00041 19.8 0.1 0.021 14.2 0.2 3.0 2 1 0 3 3 3 1 MalT-like TPR region NARP1 PF12569.8 CCH60351.1 - 0.13 11.1 27.3 0.1 11.5 0.4 4.2 2 1 3 5 5 5 0 NMDA receptor-regulated protein 1 Exonuc_VII_S PF02609.16 CCH60351.1 - 0.33 11.1 10.5 0.067 13.3 1.2 4.0 4 0 0 4 4 4 0 Exonuclease VII small subunit TPR_10 PF13374.6 CCH60351.1 - 5.9 6.9 8.7 39 4.3 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 CCH60351.1 - 8.1 6.9 6.7 1.4e+02 3.1 0.0 4.5 4 0 0 4 4 4 0 PPR repeat CTU2 PF10288.9 CCH60352.1 - 1.5e-21 76.7 0.8 1.5e-21 76.7 0.8 1.8 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Patched PF02460.18 CCH60352.1 - 0.0012 17.0 1.3 0.0024 16.1 1.3 1.4 1 0 0 1 1 1 1 Patched family DCP2 PF05026.13 CCH60353.1 - 2.3e-23 82.3 0.7 5.5e-23 81.1 0.7 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CCH60353.1 - 3.3e-13 49.8 0.0 7.7e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DHHA2 PF02833.14 CCH60353.1 - 0.024 14.8 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 DHHA2 domain SH3_1 PF00018.28 CCH60354.1 - 1.4e-26 91.8 0.3 3.5e-12 45.7 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CCH60354.1 - 2.8e-23 81.5 0.1 5.7e-11 42.1 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain FCH PF00611.23 CCH60354.1 - 1.9e-16 60.1 0.2 1.9e-16 60.1 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CCH60354.1 - 9e-10 38.1 0.0 0.00015 21.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CCH60354.1 - 0.0035 17.6 0.5 0.017 15.4 0.1 2.2 2 0 0 2 2 2 1 Bacterial SH3 domain ITAM PF02189.15 CCH60354.1 - 0.025 15.0 0.1 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif YscO PF07321.12 CCH60354.1 - 0.17 11.9 7.5 2.9 7.8 1.3 2.5 2 0 0 2 2 2 0 Type III secretion protein YscO LON_substr_bdg PF02190.16 CCH60354.1 - 0.67 9.8 5.8 0.079 12.8 1.2 1.8 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain TRAPP PF04051.16 CCH60355.1 - 4.3e-32 110.9 0.1 6.8e-32 110.2 0.1 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component DEAD PF00270.29 CCH60356.1 - 2e-48 164.5 0.0 5.8e-48 163.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60356.1 - 1.2e-32 112.6 0.0 1.6e-31 108.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH60356.1 - 0.0019 18.2 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5335 PF17269.2 CCH60356.1 - 0.0024 17.7 0.1 0.0053 16.6 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5335) UTP25 PF06862.12 CCH60356.1 - 0.0038 16.1 0.0 0.026 13.3 0.0 2.1 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 CCH60356.1 - 0.0055 17.0 0.0 0.59 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 CCH60356.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 CCH60356.1 - 0.17 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Cnd1 PF12717.7 CCH60357.1 - 5.1e-05 23.4 3.2 0.11 12.5 0.1 3.7 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCH60357.1 - 0.083 13.2 0.0 1.8e+02 2.8 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CCH60357.1 - 0.1 13.2 0.1 3.3 8.4 0.0 2.9 1 1 2 3 3 3 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CCH60357.1 - 0.11 12.0 3.7 0.15 11.6 0.0 2.7 3 1 0 3 3 3 0 CLASP N terminal RRM_1 PF00076.22 CCH60358.1 - 6.7e-18 64.3 0.1 1.5e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinocilin PF15033.6 CCH60358.1 - 0.24 11.0 0.5 0.39 10.4 0.5 1.3 1 0 0 1 1 1 0 Kinocilin protein Syja_N PF02383.18 CCH60359.1 - 2.1e-72 244.1 0.6 3.8e-72 243.3 0.6 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CCH60359.1 - 2e-13 50.4 0.0 3.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3857 PF12969.7 CCH60359.1 - 0.05 13.7 0.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) SNARE PF05739.19 CCH60360.1 - 3.3e-11 43.0 0.4 8.2e-11 41.7 0.4 1.7 1 0 0 1 1 1 1 SNARE domain DUF1319 PF07028.11 CCH60360.1 - 1.3e-05 25.3 2.6 7.4e-05 22.9 0.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1319) Rx_N PF18052.1 CCH60360.1 - 0.0017 18.6 1.0 0.013 15.8 0.1 2.4 2 0 0 2 2 2 1 Rx N-terminal domain Synaptobrevin PF00957.21 CCH60360.1 - 0.0019 18.0 0.4 0.0019 18.0 0.4 2.7 2 1 2 4 4 4 1 Synaptobrevin DUF1664 PF07889.12 CCH60360.1 - 0.016 15.2 11.8 0.17 11.9 0.8 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CCH60360.1 - 0.085 13.5 2.4 0.74 10.5 0.5 3.1 3 0 0 3 3 3 0 SlyX TEX12 PF15219.6 CCH60360.1 - 0.22 11.9 5.1 0.36 11.2 2.9 2.4 2 1 0 2 2 2 0 Testis-expressed 12 Spc7 PF08317.11 CCH60360.1 - 0.23 10.3 17.4 0.16 10.8 0.8 3.0 2 1 1 3 3 3 0 Spc7 kinetochore protein PI_PP_I PF18363.1 CCH60360.1 - 0.54 10.5 8.4 0.57 10.4 2.6 2.6 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Use1 PF09753.9 CCH60360.1 - 0.64 9.7 13.3 2.9 7.5 10.9 2.8 1 1 1 2 2 2 0 Membrane fusion protein Use1 LPD5 PF18799.1 CCH60360.1 - 2.1 8.8 6.9 0.87 10.0 4.0 1.9 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 HALZ PF02183.18 CCH60360.1 - 2.3 8.5 5.8 0.56 10.5 0.6 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF948 PF06103.11 CCH60360.1 - 2.4 8.5 6.6 8.3 6.7 0.7 3.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 CCH60360.1 - 3.1 8.4 7.7 3 8.4 3.6 2.9 2 2 0 2 2 2 0 Syntaxin 6, N-terminal THOC7 PF05615.13 CCH60360.1 - 3.4 8.0 11.3 0.73 10.1 0.5 3.4 2 2 1 3 3 3 0 Tho complex subunit 7 Aa_trans PF01490.18 CCH60361.1 - 6.8e-87 291.8 38.3 8.3e-87 291.5 38.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CCH60361.1 - 7.5e-05 21.7 39.8 0.0001 21.3 39.8 1.1 1 0 0 1 1 1 1 Amino acid permease ATP13 PF12921.7 CCH60361.1 - 0.088 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ATPase expression Glyco_transf_34 PF05637.12 CCH60362.1 - 4.8e-47 160.7 0.0 6.8e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF2971 PF11185.8 CCH60362.1 - 0.12 13.6 0.0 0.47 11.6 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) ATG27 PF09451.10 CCH60363.1 - 2.7e-40 138.9 0.1 3.5e-40 138.5 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Ribosomal_L22 PF00237.19 CCH60364.1 - 2.8e-38 130.3 1.7 1.2e-37 128.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CASP_C PF08172.12 CCH60365.1 - 1.2e-26 93.6 8.0 1.9e-22 79.8 5.5 5.8 4 1 0 4 4 4 2 CASP C terminal TRIQK PF15168.6 CCH60365.1 - 0.029 14.3 0.2 9.7 6.2 0.0 2.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Golgin_A5 PF09787.9 CCH60365.1 - 0.043 13.3 0.0 0.043 13.3 0.0 4.3 2 1 2 4 4 4 0 Golgin subfamily A member 5 MAAL_C PF07476.11 CCH60365.1 - 0.087 12.0 2.7 4.6 6.3 0.0 2.6 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus KRE9 PF05390.11 CCH60366.1 - 4.5e-44 149.4 6.1 1.2e-43 148.0 6.1 1.7 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCH60366.1 - 3.3e-09 37.4 0.6 3.3e-09 37.4 0.6 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rep_fac-A_3 PF08661.11 CCH60367.1 - 2.7e-22 79.1 0.0 3.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Replication factor A protein 3 MFS_1 PF07690.16 CCH60368.1 - 4.3e-34 118.0 22.0 6.1e-34 117.5 22.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CCH60368.1 - 2 8.1 12.5 0.077 12.7 6.1 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF2157 PF09925.9 CCH60368.1 - 7 6.4 15.4 1.9 8.3 5.7 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Arginosuc_synth PF00764.19 CCH60369.1 - 1.8e-162 541.1 0.0 2.1e-162 540.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CCH60369.1 - 1.5e-05 24.6 0.0 3.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CCH60369.1 - 0.00059 18.7 0.0 0.0009 18.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CCH60369.1 - 0.2 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DUF2401 PF10287.9 CCH60370.1 - 1.5e-81 273.3 0.7 2e-81 272.9 0.7 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCH60370.1 - 5.3e-23 81.2 0.0 1.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Longin_2 PF18639.1 CCH60371.1 - 1.2e-61 207.3 0.9 6.3e-61 205.0 0.2 2.3 2 0 0 2 2 2 1 Yeast longin domain DUF2079 PF09852.9 CCH60371.1 - 0.18 10.6 1.0 0.38 9.6 1.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) AA_permease PF00324.21 CCH60372.1 - 1e-76 258.5 47.0 1.3e-76 258.2 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH60372.1 - 1e-38 133.3 50.7 1.3e-38 132.9 50.7 1.0 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.27 CCH60373.1 - 3.1e-35 121.5 0.0 6.4e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCH60373.1 - 2.9e-15 56.1 0.0 9.1e-15 54.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CCH60373.1 - 1.2e-12 47.7 0.0 2.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 CCH60373.1 - 2.2e-10 41.2 11.5 5e-09 36.8 11.5 2.6 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_II PF14492.6 CCH60373.1 - 3.7e-07 30.2 0.0 8.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CCH60373.1 - 9.2e-05 22.8 0.1 0.00039 20.7 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu domain 2 Roc PF08477.13 CCH60373.1 - 0.0018 18.5 0.0 0.42 10.8 0.0 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCH60373.1 - 0.0029 17.1 0.0 0.16 11.4 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCH60373.1 - 0.016 15.3 0.5 0.042 13.9 0.1 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ebp2 PF05890.12 CCH60374.1 - 2.3e-89 299.5 29.5 2.3e-89 299.5 29.5 3.0 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.17 CCH60375.1 - 2.5e-96 321.6 0.1 3.7e-96 321.1 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.16 CCH60376.1 - 7.9e-34 115.4 1.1 9e-34 115.3 1.1 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CCH60376.1 - 0.028 14.8 0.0 0.036 14.4 0.0 1.3 1 1 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 Ribosomal_L14 PF00238.19 CCH60377.1 - 1.6e-40 138.0 2.2 1.8e-40 137.8 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 CCH60378.1 - 2.4e-40 138.6 2.0 8.1e-40 136.8 2.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60378.1 - 3.6e-18 65.8 0.1 6.5e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH60378.1 - 0.029 13.7 0.1 0.058 12.7 0.1 1.5 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 CCH60378.1 - 0.033 13.8 0.1 0.096 12.3 0.1 1.8 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CCH60378.1 - 0.037 13.4 0.3 0.07 12.5 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SelP_N PF04592.14 CCH60378.1 - 0.83 9.0 21.4 2.6 7.4 9.5 2.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region L51_S25_CI-B8 PF05047.16 CCH60379.1 - 2.4e-07 30.6 0.5 2.4e-07 30.6 0.5 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF16 PF01519.16 CCH60379.1 - 0.03 14.8 2.2 0.062 13.8 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Pkinase PF00069.25 CCH60380.1 - 1.4e-72 244.2 0.0 1.8e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60380.1 - 1.7e-41 142.3 0.0 2.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH60380.1 - 3e-05 23.5 0.0 6.2e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCH60380.1 - 0.011 14.7 0.2 0.027 13.4 0.2 1.6 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CCH60380.1 - 0.038 13.6 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCH60380.1 - 0.076 12.9 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CCH60380.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PigN PF04987.14 CCH60381.1 - 5.7e-131 437.5 50.4 8.2e-131 437.0 50.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CCH60381.1 - 2.7e-11 43.7 1.0 1.4e-08 34.8 1.1 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CCH60381.1 - 9.1e-11 41.7 0.1 1.4e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CCH60381.1 - 4.6e-05 22.9 0.0 8.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily TBCC_N PF16752.5 CCH60381.1 - 0.0035 17.8 0.5 0.0081 16.6 0.5 1.7 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain PIR PF00399.19 CCH60382.1 - 7.2e-56 184.7 118.9 2.3e-07 30.2 5.5 8.7 8 0 0 8 8 8 8 Yeast PIR protein repeat U3_snoRNA_assoc PF08297.11 CCH60382.1 - 0.66 10.7 3.5 2.3 9.0 3.5 1.9 1 0 0 1 1 1 0 U3 snoRNA associated PIR PF00399.19 CCH60383.1 - 9.1e-14 50.6 39.6 1.8e-05 24.1 4.9 3.9 4 0 0 4 4 4 3 Yeast PIR protein repeat YCII PF03795.14 CCH60384.1 - 7e-08 32.8 0.0 8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain PIR PF00399.19 CCH60385.1 - 7.4e-06 25.4 7.4 7.4e-06 25.4 7.4 2.5 2 0 0 2 2 2 1 Yeast PIR protein repeat zf-CCHC_2 PF13696.6 CCH60386.1 - 0.12 12.2 16.6 0.16 11.9 0.8 3.2 3 0 0 3 3 3 0 Zinc knuckle HypA PF01155.19 CCH60386.1 - 0.13 12.3 4.9 3 7.9 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2318 PF10080.9 CCH60386.1 - 0.18 11.9 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) C1_2 PF03107.16 CCH60386.1 - 2.5 8.5 12.3 4.6 7.6 3.7 2.4 2 0 0 2 2 2 0 C1 domain Vps35 PF03635.17 CCH60387.1 - 3.6e-259 862.2 39.7 4.6e-259 861.9 39.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 peroxidase PF00141.23 CCH60388.1 - 3.3e-39 134.9 0.0 6.8e-39 133.9 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Pam17 PF08566.10 CCH60389.1 - 7.5e-66 221.0 0.0 9.1e-66 220.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF4260 PF14079.6 CCH60389.1 - 0.044 13.7 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) F-box PF00646.33 CCH60390.1 - 4.7e-07 29.5 3.6 2e-06 27.5 1.2 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CCH60390.1 - 9.8e-07 28.6 0.6 9.8e-07 28.6 0.6 2.6 3 0 0 3 3 3 1 F-box-like Yip1 PF04893.17 CCH60391.1 - 7.9e-14 51.7 9.0 1.1e-13 51.3 9.0 1.3 1 0 0 1 1 1 1 Yip1 domain MMR_HSR1_Xtn PF16897.5 CCH60392.1 - 1.3e-35 121.6 0.7 2.3e-35 120.8 0.7 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CCH60392.1 - 9e-21 74.1 0.1 2e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCH60392.1 - 2.4e-19 69.1 0.0 5.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCH60392.1 - 1.2e-12 47.7 0.0 2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCH60392.1 - 0.00012 22.1 0.5 0.027 14.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 CCH60392.1 - 0.00099 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 CCH60392.1 - 0.029 13.8 0.3 0.097 12.1 0.1 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Roc PF08477.13 CCH60392.1 - 0.078 13.2 0.3 0.42 10.8 0.1 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase YchF-GTPase_C PF06071.13 CCH60392.1 - 0.14 12.4 0.1 0.82 9.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF933) RsgA_GTPase PF03193.16 CCH60392.1 - 0.52 10.2 2.6 2.3 8.1 0.2 2.8 2 1 1 3 3 3 0 RsgA GTPase Ribonuc_red_sm PF00268.21 CCH60393.1 - 1.4e-101 339.7 1.8 3.2e-101 338.4 1.8 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain SpoU_methylas_C PF12105.8 CCH60393.1 - 0.075 12.7 0.1 0.2 11.4 0.1 1.8 1 1 0 1 1 1 0 SpoU, rRNA methylase, C-terminal DUF4744 PF15918.5 CCH60393.1 - 0.17 12.7 0.0 0.47 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) zf-RRN7 PF11781.8 CCH60394.1 - 7.5e-07 28.7 0.2 1.3e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 KIX_2 PF16987.5 CCH60394.1 - 0.049 13.6 0.1 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 KIX domain SE PF08491.10 CCH60395.1 - 4.3e-119 396.6 0.0 6e-119 396.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CCH60395.1 - 1.1e-14 54.5 0.0 1.5e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCH60395.1 - 1e-05 25.3 0.1 0.00015 21.5 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH60395.1 - 0.0012 19.0 0.1 0.0027 17.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCH60395.1 - 0.0015 17.7 0.4 0.0026 16.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CCH60395.1 - 0.0049 16.1 0.7 0.025 13.8 0.1 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CCH60395.1 - 0.0065 17.0 0.1 0.017 15.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCH60395.1 - 0.037 12.7 0.8 0.093 11.4 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF2162 PF09930.9 CCH60395.1 - 0.041 13.3 0.2 0.066 12.6 0.2 1.3 1 0 0 1 1 1 0 Predicted transporter (DUF2162) Pyr_redox_2 PF07992.14 CCH60395.1 - 0.067 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCH60395.1 - 0.067 12.5 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CCH60395.1 - 0.067 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CCH60395.1 - 0.35 9.9 0.8 0.76 8.8 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A CBP4 PF07960.11 CCH60396.1 - 2.7e-45 153.4 1.3 3.1e-45 153.2 1.3 1.0 1 0 0 1 1 1 1 CBP4 HTH_WhiA PF02650.14 CCH60396.1 - 0.064 13.6 5.5 0.092 13.1 3.0 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain DUF600 PF04634.12 CCH60396.1 - 0.076 13.1 3.0 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF600 Sec10 PF07393.11 CCH60397.1 - 1.9e-51 175.4 39.8 2.5e-51 175.0 25.9 2.2 1 1 0 2 2 2 2 Exocyst complex component Sec10 SPX PF03105.19 CCH60398.1 - 7.4e-40 138.0 30.9 9.7e-40 137.7 30.9 1.1 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 CCH60398.1 - 2e-23 83.1 57.0 9.9e-21 74.2 40.7 1.9 2 1 1 3 3 3 2 Citrate transporter Peptidase_S49 PF01343.18 CCH60398.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 RNase_PH PF01138.21 CCH60399.1 - 8.9e-16 58.6 0.0 1.8e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF4909 PF16253.5 CCH60399.1 - 0.021 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) FYVE_2 PF02318.16 CCH60399.1 - 0.067 13.4 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger ELO PF01151.18 CCH60400.1 - 8.7e-58 195.8 24.8 1.2e-57 195.4 24.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family UCR_UQCRX_QCR9 PF05365.12 CCH60401.1 - 4.9e-25 87.2 4.7 5.4e-25 87.1 4.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like HlyIII PF03006.20 CCH60402.1 - 2.7e-64 217.0 15.0 3.3e-64 216.7 15.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related TssN PF17555.2 CCH60402.1 - 3 7.1 14.0 1.6 8.1 11.1 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssN Pannexin_like PF12534.8 CCH60402.1 - 7.1 5.6 8.9 0.12 11.4 1.6 1.7 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Abhydro_lipase PF04083.16 CCH60403.1 - 8.2e-11 41.3 0.0 1.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CCH60403.1 - 1e-05 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 CCH60403.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 CCH60403.1 - 0.037 13.3 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CCH60403.1 - 0.061 13.1 0.3 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Lipase_2 PF01674.18 CCH60403.1 - 0.064 12.8 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 2) POC3_POC4 PF10448.9 CCH60404.1 - 6.2e-29 100.9 1.5 7.3e-29 100.6 1.5 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 SBDS PF01172.18 CCH60405.1 - 2.4e-34 117.2 1.0 4.4e-34 116.4 1.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CCH60405.1 - 1.9e-29 102.0 0.6 1.9e-29 102.0 0.6 1.8 2 0 0 2 2 2 1 SBDS protein C-terminal domain SUV3_C PF12513.8 CCH60405.1 - 0.26 11.3 1.1 0.68 9.9 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal NIF PF03031.18 CCH60406.1 - 1.7e-52 177.3 0.5 1.7e-52 177.3 0.5 2.2 3 1 1 4 4 4 1 NLI interacting factor-like phosphatase HAD PF12710.7 CCH60406.1 - 0.074 13.4 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NPCC PF08058.11 CCH60407.1 - 5.4e-27 94.4 2.1 5.4e-27 94.4 2.1 1.9 2 0 0 2 2 2 1 Nuclear pore complex component PNP_UDP_1 PF01048.20 CCH60408.1 - 6.1e-35 120.6 0.0 7.4e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily COX17 PF05051.13 CCH60409.1 - 5.9e-23 81.0 7.7 7.3e-23 80.7 7.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 CCH60409.1 - 0.0094 16.1 5.5 0.018 15.1 5.5 1.6 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CCH60409.1 - 0.01 15.8 7.1 0.013 15.5 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 CCH60409.1 - 8 6.8 13.1 56 4.1 13.1 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) PP2C PF00481.21 CCH60410.1 - 1.4e-47 162.5 0.2 1.4e-47 162.5 0.2 2.7 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 CCH60410.1 - 2.1e-36 123.4 78.0 7.9e-10 38.4 5.0 10.8 7 3 2 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 CCH60410.1 - 1.7e-29 101.4 95.8 1.1e-05 25.7 1.6 12.1 9 4 3 12 12 12 8 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CCH60410.1 - 2e-24 86.2 0.0 4.2e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CCH60410.1 - 3.3e-05 23.4 7.2 3.3e-05 23.4 7.2 5.0 2 2 2 4 4 4 2 Leucine-rich repeat LRR_2 PF07723.13 CCH60410.1 - 0.28 11.9 1.5 50 4.8 0.2 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CCH60410.1 - 9.9 6.5 64.7 1.4 9.2 0.4 12.9 12 0 0 12 12 12 0 Leucine Rich repeat SYS1 PF09801.9 CCH60411.1 - 6.7e-49 165.7 14.0 7.8e-49 165.5 14.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DEAD PF00270.29 CCH60412.1 - 1.4e-47 161.7 0.6 3.8e-47 160.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60412.1 - 2.5e-28 98.7 1.9 1.5e-27 96.1 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCH60412.1 - 0.058 13.7 0.4 0.25 11.6 0.4 2.2 1 1 0 1 1 1 0 AAA domain COX16 PF14138.6 CCH60413.1 - 9.2e-31 106.2 0.4 1.4e-30 105.6 0.1 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 ORC_WH_C PF18137.1 CCH60414.1 - 4.5e-17 62.4 0.0 1.1e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 CCH60414.1 - 2.4e-06 26.9 9.0 4e-05 22.9 9.0 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Ribophorin_I PF04597.14 CCH60415.1 - 2.2e-119 399.6 5.8 2.4e-119 399.4 5.8 1.0 1 0 0 1 1 1 1 Ribophorin I Proteasome PF00227.26 CCH60416.1 - 1.1e-46 158.7 0.2 1.3e-46 158.5 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Fasciclin PF02469.22 CCH60417.1 - 1.8e-20 73.4 1.0 1.7e-05 25.0 0.0 6.1 5 2 0 5 5 5 5 Fasciclin domain FA_desaturase PF00487.24 CCH60418.1 - 2.5e-17 63.5 15.8 2.5e-17 63.5 15.8 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CCH60418.1 - 3.7e-14 52.6 0.0 5.9e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain YndJ PF14158.6 CCH60418.1 - 0.013 14.9 2.4 0.021 14.2 2.4 1.2 1 0 0 1 1 1 0 YndJ-like protein Zn_clus PF00172.18 CCH60419.1 - 1.9e-08 34.3 12.3 4e-08 33.3 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.17 CCH60419.1 - 2.1 8.3 17.9 3.6 7.6 17.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CCH60419.1 - 2.4 8.1 8.0 5.1 7.1 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mannosyl_trans3 PF11051.8 CCH60420.1 - 1.9e-68 230.8 3.2 3e-68 230.2 3.2 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Ribonuclease_3 PF00636.26 CCH60421.1 - 4.3e-18 65.9 0.0 4.3e-18 65.9 0.0 2.9 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 CCH60421.1 - 4.9e-14 52.8 0.1 5.1e-06 27.1 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 CCH60421.1 - 2.4e-13 50.3 0.0 6.9e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like Utp14 PF04615.13 CCH60421.1 - 6.1 5.3 22.9 11 4.4 22.9 1.5 1 0 0 1 1 1 0 Utp14 protein TFIID-18kDa PF02269.16 CCH60422.1 - 8.8e-33 112.2 0.0 1.3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 CCH60422.1 - 0.13 12.6 6.3 0.51 10.7 0.0 2.5 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF4611 PF15387.6 CCH60422.1 - 0.18 12.1 9.4 0.25 11.6 8.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 CCH60422.1 - 1.3 8.7 8.2 1.9 8.1 8.2 1.3 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 CCH60422.1 - 1.3 7.1 6.3 1.3 7.1 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 CCH60422.1 - 3.3 8.1 12.9 5.5 7.4 12.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ERO1 PF04137.15 CCH60423.1 - 3.9e-117 391.4 2.3 3.9e-117 391.4 2.3 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) VirB8 PF04335.13 CCH60423.1 - 0.089 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 VirB8 protein KIP1 PF07765.12 CCH60423.1 - 1.2 9.3 4.5 24 5.1 0.1 3.3 4 0 0 4 4 4 0 KIP1-like protein VPS9 PF02204.18 CCH60424.1 - 5.1e-27 94.1 0.0 1.5e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CCH60424.1 - 5.2e-12 45.9 0.5 5.2e-12 45.9 0.5 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF5601) CUE PF02845.16 CCH60424.1 - 7.9e-07 28.7 0.0 2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 CUE domain Mrr_N PF14338.6 CCH60424.1 - 0.1 12.7 0.9 0.75 10.0 0.0 2.8 3 1 0 3 3 3 0 Mrr N-terminal domain Asn_synthase PF00733.21 CCH60425.1 - 1.6e-19 70.8 0.0 1.7e-10 41.1 0.0 2.7 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCH60425.1 - 1.3e-13 51.0 0.0 3.1e-12 46.5 0.0 2.6 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCH60425.1 - 1.3e-06 28.6 0.0 6.5e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCH60425.1 - 0.0012 18.3 0.0 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein zf-NOSIP PF15906.5 CCH60425.1 - 0.068 13.3 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Rad10 PF03834.14 CCH60426.1 - 1.1e-37 128.5 0.4 1.6e-37 128.0 0.4 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Prefoldin PF02996.17 CCH60427.1 - 5.9e-26 90.7 3.7 7.2e-26 90.5 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Fib_alpha PF08702.10 CCH60427.1 - 0.048 13.8 10.0 1.6 8.9 10.0 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 CCH60427.1 - 0.095 12.7 5.4 1.1 9.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Utp14 PF04615.13 CCH60428.1 - 4.3e-190 634.0 80.2 4.3e-190 634.0 80.2 2.1 1 1 1 2 2 2 1 Utp14 protein DUF1773 PF08593.10 CCH60428.1 - 0.028 15.4 2.9 16 6.6 0.9 3.6 2 0 0 2 2 2 0 Domain of unknown function Proteasome PF00227.26 CCH60429.1 - 2e-56 190.5 0.0 2.5e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH60429.1 - 2e-09 37.0 0.4 4.8e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RPM2 PF08579.11 CCH60430.1 - 4.2e-36 124.0 2.9 4.2e-36 124.0 2.9 4.3 4 1 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) NMT PF01233.19 CCH60430.1 - 0.15 11.9 1.1 0.32 10.8 0.3 1.9 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain RVT_1 PF00078.27 CCH60431.1 - 1.5e-10 41.0 1.1 3e-10 40.0 0.6 1.7 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 CCH60431.1 - 4.9e-09 36.1 0.0 1.1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CheW PF01584.19 CCH60431.1 - 0.094 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 CheW-like domain rve PF00665.26 CCH60432.1 - 2e-09 37.7 0.0 2.9e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain IGPD PF00475.18 CCH60432.1 - 0.076 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase ABC_membrane PF00664.23 CCH60433.1 - 6.8e-62 209.6 44.0 1.2e-37 130.1 14.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCH60433.1 - 1.6e-47 161.5 0.2 7.5e-28 97.8 0.0 3.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCH60433.1 - 5.1e-13 49.0 0.0 0.00013 21.5 0.0 4.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCH60433.1 - 2.1e-09 38.2 17.0 8.3e-09 36.2 2.6 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CCH60433.1 - 3.7e-08 33.0 0.0 0.0014 18.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CCH60433.1 - 2.8e-06 27.4 1.0 0.19 11.5 0.0 4.6 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CCH60433.1 - 2.2e-05 24.5 0.0 0.051 13.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CCH60433.1 - 8e-05 22.3 0.2 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CCH60433.1 - 0.00011 22.2 2.8 0.37 10.9 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CCH60433.1 - 0.00018 22.0 0.2 0.25 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CCH60433.1 - 0.0002 21.9 0.0 0.86 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CCH60433.1 - 0.00023 21.0 0.4 1.7 8.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 CCH60433.1 - 0.00025 20.2 0.0 0.025 13.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 CCH60433.1 - 0.00032 21.0 0.6 2.1 8.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 CCH60433.1 - 0.0017 18.4 5.0 0.28 11.2 0.0 3.6 4 0 0 4 4 3 1 Dynamin family Mg_chelatase PF01078.21 CCH60433.1 - 0.014 14.8 0.0 0.068 12.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 CCH60433.1 - 0.018 14.8 0.5 6.2 6.5 0.0 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CCH60433.1 - 0.02 14.3 0.0 5.4 6.3 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 CCH60433.1 - 0.02 15.3 0.4 0.69 10.3 0.1 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 CCH60433.1 - 0.031 13.8 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Vps51 PF08700.11 CCH60433.1 - 0.034 14.2 3.3 3.1 7.9 0.1 3.0 2 0 0 2 2 2 0 Vps51/Vps67 DEAD PF00270.29 CCH60433.1 - 0.041 13.6 0.3 50 3.6 0.0 3.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase PduV-EutP PF10662.9 CCH60433.1 - 0.042 13.6 0.6 0.49 10.1 0.0 2.9 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 CCH60433.1 - 0.045 13.9 0.1 6.7 6.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCH60433.1 - 0.051 13.3 2.9 2.1 8.0 0.0 3.7 5 0 0 5 5 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.25 CCH60433.1 - 0.053 13.2 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.23 CCH60433.1 - 0.061 13.4 0.0 3.7 7.6 0.0 3.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CCH60433.1 - 0.08 12.9 0.2 0.87 9.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CCH60433.1 - 0.085 12.1 0.1 5 6.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 CCH60433.1 - 0.092 13.1 0.4 2.7 8.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 CCH60433.1 - 0.094 12.7 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 CCH60433.1 - 0.12 11.4 0.1 0.24 10.3 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 CCH60433.1 - 0.15 11.5 0.0 21 4.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 CCH60433.1 - 0.24 11.0 0.4 9.7 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CCH60433.1 - 0.57 10.2 0.0 0.57 10.2 0.0 2.6 3 0 0 3 3 1 0 Helicase HerA, central domain HA2 PF04408.23 CCH60435.1 - 4.1e-21 75.3 0.0 1.1e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCH60435.1 - 5.3e-13 49.1 0.0 1.6e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCH60435.1 - 1.4e-09 38.3 0.0 5e-09 36.5 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCH60435.1 - 6.7e-09 35.8 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH60435.1 - 9.4e-07 29.2 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH60435.1 - 0.00043 20.6 0.0 0.00096 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CCH60435.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CCH60435.1 - 0.0038 17.7 0.4 0.18 12.3 0.1 3.2 2 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CCH60435.1 - 0.0053 16.7 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase SRP54 PF00448.22 CCH60435.1 - 0.0062 16.2 0.0 0.023 14.3 0.0 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CCH60435.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCH60435.1 - 0.011 15.5 0.2 0.047 13.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCH60435.1 - 0.042 13.3 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 CCH60435.1 - 0.079 12.9 0.1 0.23 11.5 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CCH60435.1 - 0.097 12.6 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Flavi_DEAD PF07652.14 CCH60435.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Suf PF05843.14 CCH60436.1 - 1e-55 189.8 26.9 1.7e-50 172.7 5.9 4.0 2 2 2 4 4 4 2 Suppressor of forked protein (Suf) SH3_2 PF07653.17 CCH60437.1 - 3e-07 30.0 0.0 5.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCH60437.1 - 3.4e-07 29.7 0.1 9e-07 28.4 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH60437.1 - 7.2e-06 25.8 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain RseA_C PF03873.13 CCH60437.1 - 0.4 11.0 0.0 0.4 11.0 0.0 4.1 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain PseudoU_synth_2 PF00849.22 CCH60438.1 - 7.6e-25 87.9 0.0 1.1e-24 87.4 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0547 PF10571.9 CCH60438.1 - 0.11 12.6 0.2 0.2 11.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Ank_2 PF12796.7 CCH60440.1 - 6.3e-26 90.8 0.7 9.8e-11 42.1 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 CCH60440.1 - 3.2e-18 66.8 17.4 1.7e-08 34.8 0.0 3.5 2 1 2 4 4 4 3 SPX domain Ank_4 PF13637.6 CCH60440.1 - 1.8e-12 47.5 0.4 0.00041 20.9 0.3 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH60440.1 - 5.5e-12 44.8 0.5 0.72 10.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CCH60440.1 - 1.6e-11 44.1 2.6 0.04 14.4 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CCH60440.1 - 1.3e-10 41.2 10.8 0.00074 19.8 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) GDPD PF03009.17 CCH60440.1 - 1.8e-07 31.1 0.0 1.3e-05 25.0 0.0 2.6 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Lectin_N PF03954.14 CCH60441.1 - 0.013 15.2 0.1 0.043 13.6 0.1 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain RTT107_BRCT_6 PF16771.5 CCH60442.1 - 1.7e-30 105.5 12.0 1.3e-29 102.7 2.4 3.5 3 0 0 3 3 3 2 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CCH60442.1 - 6.6e-25 86.9 0.7 2e-23 82.2 0.2 3.1 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CCH60442.1 - 3.4e-07 30.6 12.1 0.00011 22.5 0.1 5.5 5 1 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCH60442.1 - 8.4e-07 29.3 11.2 0.063 13.7 0.3 5.4 6 0 0 6 6 6 3 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CCH60442.1 - 0.00035 20.6 0.2 2 8.6 0.0 3.8 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCH60442.1 - 0.0094 15.9 0.0 2.8 7.9 0.0 2.7 2 0 0 2 2 2 2 twin BRCT domain Globin PF00042.22 CCH60443.1 - 6.7e-09 36.3 0.0 2.6e-08 34.4 0.0 2.0 3 0 0 3 3 3 1 Globin FAD_binding_6 PF00970.24 CCH60443.1 - 1.4e-08 35.0 0.0 2.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCH60443.1 - 9.5e-08 32.7 0.0 2.1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 CCH60443.1 - 0.039 13.8 0.1 0.12 12.3 0.1 1.8 1 1 0 1 1 1 0 Protoglobin NAD_binding_6 PF08030.12 CCH60443.1 - 0.043 13.9 1.2 0.31 11.1 0.7 2.3 2 1 1 3 3 3 0 Ferric reductase NAD binding domain DUF416 PF04222.12 CCH60444.1 - 0.026 14.0 0.3 0.028 13.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF416) A_thal_3526 PF09713.10 CCH60444.1 - 0.053 13.8 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Polyoma_coat PF00718.20 CCH60444.1 - 0.16 11.2 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein REC104 PF17378.2 CCH60445.1 - 0.0041 16.9 0.6 0.0064 16.3 0.6 1.5 1 0 0 1 1 1 1 Meiotic recombination protein REC104 Kelch_5 PF13854.6 CCH60446.1 - 1.8e-29 101.2 4.2 1.1e-05 25.3 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CCH60446.1 - 5e-28 96.9 6.4 0.00041 20.3 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 CCH60446.1 - 6.8e-26 89.7 6.0 2.7e-05 24.3 0.1 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CCH60446.1 - 5e-24 84.0 1.8 0.00015 22.0 0.0 6.5 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 CCH60446.1 - 9.2e-19 66.8 0.5 9.5e-05 21.9 0.0 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CCH60446.1 - 3.5e-11 42.6 5.2 0.072 13.1 0.1 6.3 6 0 0 6 6 6 3 Kelch motif TSC22 PF01166.18 CCH60446.1 - 0.27 11.6 14.6 0.33 11.3 1.5 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family TDA11 PF17084.5 CCH60447.1 - 1.3e-13 50.7 39.8 1.6e-08 34.0 20.0 2.7 1 1 1 2 2 2 2 Topoisomerase I damage affected protein 11 FKS1_dom1 PF14288.6 CCH60448.1 - 0.96 9.8 4.4 0.46 10.8 1.8 1.8 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 ATP-grasp_2 PF08442.10 CCH60449.1 - 5.1e-72 241.7 2.1 8.2e-72 241.0 2.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CCH60449.1 - 1.7e-21 76.6 0.1 3.8e-20 72.3 0.1 2.4 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 CCH60449.1 - 4e-05 23.2 0.5 8.5e-05 22.1 0.5 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CCH60449.1 - 0.0029 17.4 0.2 0.0082 15.9 0.2 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HIN PF02760.15 CCH60449.1 - 0.042 13.5 0.4 0.11 12.2 0.4 1.6 1 0 0 1 1 1 0 HIN-200/IF120x domain RimK PF08443.11 CCH60449.1 - 0.064 12.8 0.2 1.2 8.7 0.0 2.4 1 1 1 2 2 2 0 RimK-like ATP-grasp domain SDA1 PF05285.12 CCH60450.1 - 4.7e-95 319.0 42.4 4.7e-95 319.0 42.4 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CCH60450.1 - 3.4e-22 78.5 0.4 1.1e-21 76.9 0.4 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Trans_reg_C PF00486.28 CCH60450.1 - 0.023 14.8 0.8 0.19 11.9 0.1 2.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Glucosamine_iso PF01182.20 CCH60451.1 - 7.4e-58 196.1 0.0 8.5e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GTP1_OBG PF01018.22 CCH60452.1 - 1.2e-36 125.7 1.0 1.3e-27 96.3 2.1 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CCH60452.1 - 3.2e-21 75.5 0.0 5.6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH60452.1 - 1e-08 34.8 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 CCH60452.1 - 4.3e-07 29.6 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCH60452.1 - 0.0042 16.5 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CCH60452.1 - 0.11 12.4 0.1 8.8 6.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase NMD3 PF04981.13 CCH60453.1 - 9.1e-84 280.7 3.4 1.6e-83 279.9 3.4 1.4 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 CCH60453.1 - 0.078 13.0 5.4 5 7.2 1.4 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CCH60453.1 - 0.21 11.6 7.3 3.7 7.7 7.3 2.6 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.12 CCH60453.1 - 0.44 10.4 4.9 13 5.7 0.5 3.5 4 0 0 4 4 4 0 NinF protein Bromodomain PF00439.25 CCH60454.1 - 1.5e-26 92.2 2.6 3.8e-26 91.0 2.6 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CCH60454.1 - 4.7e-09 36.5 0.0 8.7e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCH60454.1 - 1.9e-05 24.6 0.0 3.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCH60454.1 - 0.00051 20.4 0.1 0.0011 19.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasome PF00227.26 CCH60455.1 - 1.3e-55 187.8 0.1 1.8e-55 187.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH60455.1 - 2.2e-12 46.4 0.0 5.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RPAP3_C PF13877.6 CCH60456.1 - 0.096 13.2 0.1 0.58 10.7 0.0 2.2 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 GCP_N_terminal PF17681.1 CCH60457.1 - 5.3e-35 121.5 0.2 7.8e-34 117.7 0.0 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal Enolase_C PF00113.22 CCH60458.1 - 5.9e-148 491.9 0.0 8.4e-148 491.4 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CCH60458.1 - 2.3e-58 196.0 0.3 3.7e-58 195.4 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CCH60458.1 - 1.3e-05 24.9 0.0 2.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like Erv26 PF04148.13 CCH60459.1 - 3.1e-85 285.2 4.4 3.6e-85 285.0 4.4 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.13 CCH60459.1 - 0.0057 17.0 8.7 0.0079 16.5 7.7 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF996) ST7 PF04184.12 CCH60459.1 - 3.4 6.0 5.8 5.2 5.4 5.8 1.2 1 0 0 1 1 1 0 ST7 protein Cytochrom_C_asm PF01578.20 CCH60459.1 - 9.6 5.9 10.5 1.6 8.4 4.4 2.3 1 1 1 2 2 2 0 Cytochrome C assembly protein 6PGD PF00393.19 CCH60460.1 - 4.2e-127 423.5 0.0 5.2e-127 423.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CCH60460.1 - 9e-50 168.9 0.0 1.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CCH60460.1 - 0.087 13.1 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CCH60460.1 - 0.12 12.9 0.1 0.25 12.0 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF5612 PF18462.1 CCH60460.1 - 0.14 11.9 0.0 1 9.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5612) 2-Hacid_dh_C PF02826.19 CCH60460.1 - 0.17 11.2 0.0 0.42 10.0 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HA2 PF04408.23 CCH60461.1 - 4.4 7.6 6.0 53 4.1 6.0 3.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) MFS_1 PF07690.16 CCH60462.1 - 7.9e-33 113.8 21.8 9.3e-33 113.6 21.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CCH60462.1 - 0.078 11.8 12.8 0.23 10.3 1.5 2.5 3 0 0 3 3 3 0 MFS_1 like family Elong_Iki1 PF10483.9 CCH60463.1 - 1.3e-61 208.7 1.0 1.5e-61 208.5 1.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Vmethyltransf PF01660.17 CCH60463.1 - 0.043 12.7 0.1 0.1 11.5 0.1 1.7 1 1 0 1 1 1 0 Viral methyltransferase Gpi16 PF04113.14 CCH60464.1 - 3.8e-160 534.0 0.1 5.2e-160 533.6 0.1 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component TT_ORF1 PF02956.14 CCH60464.1 - 0.0034 16.1 0.6 0.0061 15.3 0.6 1.3 1 0 0 1 1 1 1 TT viral orf 1 HEAT_2 PF13646.6 CCH60465.1 - 3.9e-08 33.6 0.0 0.3 11.5 0.0 6.3 6 1 1 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 CCH60465.1 - 1.6e-05 25.3 0.0 6.7 7.3 0.0 6.0 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 CCH60465.1 - 0.0005 20.1 11.6 19 5.8 0.1 8.2 7 0 0 7 7 7 0 HEAT repeat UME PF08064.13 CCH60465.1 - 0.0008 19.3 4.8 0.098 12.6 0.1 5.1 4 1 2 6 6 6 1 UME (NUC010) domain IFRD PF05004.13 CCH60465.1 - 0.001 18.2 0.3 0.087 11.9 0.3 3.3 3 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 CCH60465.1 - 0.0011 19.0 20.8 0.25 11.4 0.1 5.3 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 CCH60465.1 - 0.0066 16.4 0.2 0.0066 16.4 0.2 5.4 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) SPG48 PF14764.6 CCH60465.1 - 0.0069 16.8 0.3 0.028 14.9 0.0 2.2 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking RTP1_C1 PF10363.9 CCH60465.1 - 0.022 15.0 4.6 6.9 6.9 0.2 4.6 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CCH60465.1 - 0.034 14.8 6.4 1e+02 3.6 0.0 6.6 4 2 4 8 8 8 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CCH60465.1 - 0.49 10.5 8.5 0.83 9.7 0.0 4.4 4 1 0 5 5 5 0 Parkin co-regulated protein RPAP3_C PF13877.6 CCH60465.1 - 7 7.3 14.2 45 4.7 1.3 6.1 5 2 1 6 6 6 0 Potential Monad-binding region of RPAP3 Adaptin_N PF01602.20 CCH60466.1 - 4e-80 269.8 25.3 5e-80 269.5 25.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCH60466.1 - 7.8e-09 35.8 0.7 7.8e-09 35.8 0.7 3.9 2 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCH60466.1 - 0.00015 22.1 1.1 0.69 10.3 0.0 3.6 2 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CCH60466.1 - 0.0061 16.7 2.5 26 5.5 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat RNA_pol_3_Rpc31 PF11705.8 CCH60466.1 - 0.085 13.1 22.6 0.15 12.3 22.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 CCH60466.1 - 0.44 9.8 20.3 0.16 11.3 17.6 1.7 2 0 0 2 2 2 0 NOA36 protein PPP4R2 PF09184.11 CCH60466.1 - 1.2 8.7 24.1 2.4 7.7 24.1 1.5 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 CCH60466.1 - 1.4 7.1 23.1 2.8 6.0 23.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CCH60466.1 - 6.8 4.8 16.5 10 4.2 16.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Aminotran_4 PF01063.19 CCH60467.1 - 1.6e-15 57.6 0.0 2.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Erf4 PF10256.9 CCH60467.1 - 0.033 14.3 1.9 0.31 11.1 1.9 2.4 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Kdo PF06293.14 CCH60468.1 - 3.9e-07 29.6 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CCH60468.1 - 0.0023 17.3 0.6 0.003 17.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 CCH60468.1 - 0.003 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CCH60468.1 - 0.0052 16.7 0.7 1.8 8.4 1.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIN_11 PF18479.1 CCH60468.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 PIN like domain DUF1679 PF07914.11 CCH60468.1 - 0.094 11.5 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) tRNA-synt_1g PF09334.11 CCH60469.1 - 2.3e-154 513.9 0.5 4.2e-154 513.0 0.5 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.10 CCH60469.1 - 2.7e-41 140.9 0.8 2.7e-41 140.9 0.8 1.9 2 0 0 2 2 2 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 CCH60469.1 - 1.5e-10 40.0 1.0 0.00029 19.3 0.0 2.7 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCH60469.1 - 0.0022 18.0 0.0 0.006 16.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCH60469.1 - 0.013 14.8 0.0 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.29 CCH60470.1 - 3.6e-47 160.4 0.8 7.4e-47 159.4 0.1 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60470.1 - 1.2e-25 90.0 0.1 8.1e-25 87.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCH60470.1 - 9e-19 67.5 0.6 1.6e-18 66.6 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCH60470.1 - 2.1e-05 24.6 0.0 4.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCH60470.1 - 4.4e-05 22.8 0.0 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 CCH60470.1 - 0.0098 15.2 0.0 0.029 13.6 0.0 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.6 CCH60470.1 - 0.13 12.0 0.0 1.6 8.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCH60470.1 - 0.18 12.1 1.7 0.61 10.4 1.0 2.4 2 1 0 2 2 2 0 AAA domain PhoD PF09423.10 CCH60471.1 - 0.00032 19.8 0.0 0.013 14.6 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Glyco_tranf_2_4 PF13704.6 CCH60473.1 - 0.08 13.5 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF3437 PF11919.8 CCH60473.1 - 0.2 11.6 1.3 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Ribosomal_L29 PF00831.23 CCH60473.1 - 1 9.4 3.3 3.5 7.7 0.0 3.0 3 0 0 3 3 3 0 Ribosomal L29 protein Pkinase PF00069.25 CCH60474.1 - 3.3e-46 157.8 4.1 4.7e-44 150.7 4.1 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60474.1 - 4.9e-24 85.0 1.9 3.5e-23 82.2 1.1 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH60474.1 - 2.1e-06 26.8 0.1 4.4e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CCH60474.1 - 0.0028 17.6 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CCH60474.1 - 0.16 11.3 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_3_Rpc31 PF11705.8 CCH60474.1 - 0.19 11.9 0.2 0.41 10.9 0.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GTP_cyclohydroI PF01227.22 CCH60475.1 - 3.4e-75 251.4 0.2 4.2e-75 251.1 0.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CCH60475.1 - 4.6e-05 23.5 0.0 0.00018 21.6 0.0 2.0 2 0 0 2 2 2 1 QueF-like protein DnaJ_CXXCXGXG PF00684.19 CCH60476.1 - 0.012 16.0 0.7 0.025 14.9 0.7 1.4 1 0 0 1 1 1 0 DnaJ central domain DUF5401 PF17380.2 CCH60476.1 - 0.041 12.0 18.3 0.064 11.3 18.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) eIF3_subunit PF08597.10 CCH60476.1 - 0.074 12.9 12.7 0.12 12.3 12.7 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AAA PF00004.29 CCH60477.1 - 6.1e-54 182.0 0.0 1.2e-42 145.4 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH60477.1 - 3.8e-08 33.0 0.0 4.4e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain IstB_IS21 PF01695.17 CCH60477.1 - 6.5e-07 29.3 0.0 7.4e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 CCH60477.1 - 1.2e-06 29.0 0.0 5.9e-05 23.5 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CCH60477.1 - 4e-06 27.1 0.0 1.8e-05 24.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCH60477.1 - 3.6e-05 23.8 0.0 0.0012 18.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCH60477.1 - 0.00051 19.5 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 CCH60477.1 - 0.00054 20.0 0.5 0.0067 16.4 0.0 3.1 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 CCH60477.1 - 0.00061 19.9 0.0 0.86 9.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CCH60477.1 - 0.0022 17.2 0.0 0.89 8.6 0.0 3.4 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 CCH60477.1 - 0.0027 17.0 0.0 0.034 13.4 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_14 PF13173.6 CCH60477.1 - 0.0034 17.4 0.5 0.039 14.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 CCH60477.1 - 0.0041 17.4 0.3 0.22 11.8 0.1 3.5 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CCH60477.1 - 0.011 15.5 0.0 0.85 9.3 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CCH60477.1 - 0.012 15.1 0.0 0.28 10.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 CCH60477.1 - 0.014 15.1 0.0 0.23 11.2 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCH60477.1 - 0.016 15.4 0.3 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCH60477.1 - 0.024 15.0 0.0 0.1 13.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CCH60477.1 - 0.026 15.0 1.5 0.14 12.7 0.0 3.1 3 0 0 3 3 2 0 ABC transporter AAA_33 PF13671.6 CCH60477.1 - 0.028 14.6 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 CCH60477.1 - 0.031 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 Bromodomain AAA_3 PF07726.11 CCH60477.1 - 0.074 12.9 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCH60477.1 - 0.085 12.6 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CCH60477.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH60477.1 - 0.21 12.1 0.0 0.21 12.1 0.0 4.0 5 0 0 5 5 3 0 AAA domain AAA_11 PF13086.6 CCH60477.1 - 0.59 9.9 0.0 0.59 9.9 0.0 4.1 4 0 0 4 4 3 0 AAA domain Amidase PF01425.21 CCH60478.1 - 1.4e-95 320.9 0.0 1.7e-95 320.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.14 CCH60479.1 - 3.5e-11 43.1 7.5 7.2e-11 42.0 7.1 1.6 1 1 0 1 1 1 1 Dynamitin Dynactin_p22 PF07426.11 CCH60479.1 - 0.029 14.2 14.3 0.012 15.4 6.4 3.0 2 1 0 2 2 2 0 Dynactin subunit p22 Cas6b_N PF17955.1 CCH60479.1 - 0.066 13.3 0.9 0.18 11.9 0.1 2.2 2 0 0 2 2 2 0 Cas6b N-terminal domain NPV_P10 PF05531.12 CCH60479.1 - 0.29 11.6 16.6 0.1 13.1 0.9 3.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.12 CCH60479.1 - 0.67 9.9 5.2 1 9.2 0.3 3.2 3 0 0 3 3 3 0 Heat shock factor binding protein 1 CLZ PF16526.5 CCH60479.1 - 3.8 7.9 6.4 7.5 7.0 0.0 3.8 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 CCH60479.1 - 3.9 7.9 14.5 0.68 10.4 1.0 3.4 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Sec63 PF02889.16 CCH60480.1 - 2.1e-115 384.3 1.7 1.6e-79 266.8 0.1 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 CCH60480.1 - 1.4e-49 168.2 0.8 5.1e-26 91.5 0.5 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 CCH60480.1 - 2.8e-30 105.6 0.2 1e-13 51.7 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCH60480.1 - 4.6e-18 65.6 0.0 1.9e-07 31.4 0.0 3.9 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA PF00004.29 CCH60480.1 - 2.5e-06 27.9 1.1 0.15 12.5 0.0 4.3 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CCH60480.1 - 7.1e-05 23.2 0.3 0.028 14.8 0.2 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CCH60480.1 - 0.00026 20.5 0.0 0.031 13.7 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 CCH60480.1 - 0.00063 20.0 6.4 0.18 12.1 0.3 4.5 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CCH60480.1 - 0.0029 17.3 0.6 2.7 7.7 0.0 3.9 5 0 0 5 5 5 1 IstB-like ATP binding protein Helicase_PWI PF18149.1 CCH60480.1 - 0.017 15.3 0.1 0.07 13.3 0.1 2.1 1 0 0 1 1 1 0 N-terminal helicase PWI domain FANCI_S1-cap PF14674.6 CCH60480.1 - 0.19 11.8 3.8 49 4.1 0.0 4.6 5 0 0 5 5 5 0 FANCI solenoid 1 cap AAA_11 PF13086.6 CCH60480.1 - 0.22 11.3 0.7 1 9.1 0.0 2.4 3 1 0 3 3 3 0 AAA domain Efg1 PF10153.9 CCH60481.1 - 6.1e-31 107.1 9.1 6.1e-31 107.1 9.1 2.3 3 0 0 3 3 3 1 rRNA-processing protein Efg1 DUF2406 PF10295.9 CCH60482.1 - 2.8e-28 98.4 0.7 6.3e-28 97.3 0.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.21 CCH60483.1 - 7.5e-61 206.3 0.1 1e-60 205.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Phage_Treg PF04761.12 CCH60483.1 - 0.013 15.6 0.3 0.077 13.1 0.1 2.4 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator Peptidase_S10 PF00450.22 CCH60484.1 - 8.2e-128 427.4 2.2 9.7e-128 427.1 2.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3591 PF12157.8 CCH60486.1 - 8.7e-168 558.5 0.5 8.7e-168 558.5 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CCH60486.1 - 3.8e-06 26.6 1.4 8.3e-06 25.5 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CCH60486.1 - 0.082 13.0 0.4 0.16 12.1 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle F-112 PF09645.10 CCH60486.1 - 0.56 10.3 4.7 0.79 9.9 3.1 2.0 2 0 0 2 2 2 0 F-112 protein RNase_T PF00929.24 CCH60488.1 - 3.4e-07 31.0 0.0 8.7e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Lambda_CIII PF02061.16 CCH60488.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.5 1 0 0 1 1 1 0 Lambda Phage CIII DLIC PF05783.11 CCH60489.1 - 0.00042 19.3 0.0 0.00055 18.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) Baculo_p74 PF04583.12 CCH60489.1 - 0.055 13.0 2.2 0.15 11.5 0.1 2.1 2 0 0 2 2 2 0 Baculoviridae p74 conserved region Phage_int_SAM_5 PF13102.6 CCH60489.1 - 0.07 13.5 1.3 2.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Phage integrase SAM-like domain CCM2_C PF16545.5 CCH60489.1 - 0.12 13.0 0.4 34 5.1 0.0 2.8 3 0 0 3 3 3 0 Cerebral cavernous malformation protein, harmonin-homology GATase_6 PF13522.6 CCH60490.1 - 2.5e-13 50.4 0.0 6.1e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCH60490.1 - 2.1e-09 37.4 0.0 3.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CCH60490.1 - 2.8e-08 33.4 0.0 5.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CCH60490.1 - 0.0027 16.6 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ABC_membrane PF00664.23 CCH60491.1 - 8.1e-46 156.9 13.6 1.1e-45 156.5 13.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCH60491.1 - 8.4e-36 123.5 0.1 3e-35 121.7 0.0 2.0 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 CCH60491.1 - 2.8e-08 33.5 0.1 0.00039 19.9 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH60491.1 - 0.00018 21.2 0.2 0.00043 20.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCH60491.1 - 0.00031 20.7 0.2 0.0029 17.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCH60491.1 - 0.00075 19.9 0.0 0.0016 18.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH60491.1 - 0.001 19.4 0.0 0.0082 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH60491.1 - 0.0034 17.1 0.0 0.012 15.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CCH60491.1 - 0.0057 16.4 7.9 0.0074 16.0 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 CCH60491.1 - 0.012 14.7 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 CCH60491.1 - 0.013 16.0 0.1 0.013 16.0 0.1 3.8 4 0 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 CCH60491.1 - 0.018 14.9 0.2 0.065 13.1 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 CCH60491.1 - 0.022 13.9 0.0 0.058 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CCH60491.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CCH60491.1 - 0.045 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP-synt_ab PF00006.25 CCH60491.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 CCH60491.1 - 0.09 12.8 0.0 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CCH60491.1 - 0.12 12.4 0.0 1.1 9.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA12 PF10443.9 CCH60492.1 - 7e-174 578.7 2.8 1.5e-173 577.6 1.1 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 CCH60492.1 - 2e-07 30.7 0.0 5.5e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 CCH60492.1 - 2e-05 24.6 1.8 9.1e-05 22.5 0.4 2.7 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCH60492.1 - 0.004 17.2 0.8 0.048 13.7 0.0 3.1 4 0 0 4 4 4 1 AAA domain USP7_C2 PF14533.6 CCH60493.1 - 4.7e-59 199.6 12.0 2.9e-57 193.7 4.1 3.0 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 CCH60493.1 - 9.2e-49 166.2 1.5 9.2e-49 166.2 1.5 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CCH60493.1 - 1.3e-36 126.1 11.3 2e-34 119.0 1.3 3.3 2 2 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CCH60493.1 - 2.6e-20 73.3 0.3 1.5e-19 70.8 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.8 CCH60493.1 - 0.00094 19.6 1.6 0.11 13.0 0.3 3.6 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 CCH60493.1 - 0.011 15.5 0.1 0.46 10.3 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin family CTP_transf_like PF01467.26 CCH60494.1 - 1.7e-13 51.0 0.0 3.2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like MA3 PF02847.17 CCH60495.1 - 4.3e-24 84.7 0.6 4.3e-24 84.7 0.6 2.3 2 0 0 2 2 2 1 MA3 domain RSF PF14876.6 CCH60495.1 - 0.0008 18.5 1.7 0.0008 18.5 1.7 1.6 2 0 0 2 2 2 1 Respiratory growth transcriptional regulator Glyco_hydro_17 PF00332.18 CCH60496.1 - 1.4e-09 38.0 0.3 1.4e-09 38.0 0.3 2.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 PAP1 PF08601.10 CCH60496.1 - 0.08 12.7 19.2 0.34 10.6 19.8 1.7 2 0 0 2 2 2 0 Transcription factor PAP1 EVI2A PF05399.11 CCH60496.1 - 1.2 8.7 16.4 2 8.0 16.4 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) GCOM2 PF15328.6 CCH60496.1 - 3 8.2 10.4 4.8 7.5 10.4 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Presenilin PF01080.17 CCH60496.1 - 3.5 6.3 8.6 4.7 5.9 8.6 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 CCH60496.1 - 3.9 5.9 14.0 4.7 5.6 14.0 1.1 1 0 0 1 1 1 0 Macoilin family Glucan_synthase PF02364.15 CCH60497.1 - 0 1295.2 14.8 0 1295.2 14.8 3.0 2 1 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCH60497.1 - 2.5e-43 147.5 0.4 1e-42 145.5 0.4 2.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 CCH60498.1 - 1.6e-144 481.0 13.7 2.1e-144 480.6 13.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CCH60498.1 - 2.8e-27 95.2 6.3 2.8e-27 95.2 6.3 3.0 3 0 0 3 3 3 1 X8 domain G-patch PF01585.23 CCH60499.1 - 3.1e-08 33.4 0.0 8.2e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CCH60499.1 - 0.0083 16.2 0.0 0.0083 16.2 0.0 4.2 2 1 0 2 2 2 1 G-patch domain MDM1 PF15501.6 CCH60499.1 - 0.064 12.4 37.0 0.08 12.1 37.0 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 GREB1 PF15782.5 CCH60499.1 - 0.25 8.4 20.8 0.28 8.3 20.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4551 PF15087.6 CCH60499.1 - 0.51 9.1 17.4 0.59 8.9 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF3435 PF11917.8 CCH60499.1 - 1.6 7.6 17.3 2.2 7.1 17.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) CDC45 PF02724.14 CCH60499.1 - 3.3 5.9 31.6 4.4 5.5 31.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Importin_rep_6 PF18829.1 CCH60500.1 - 4.3e-35 120.1 3.4 4.3e-35 120.1 3.4 4.0 3 0 0 3 3 3 1 Importin repeat 6 Importin_rep_4 PF18808.1 CCH60500.1 - 3.9e-31 107.2 0.6 3.9e-31 107.2 0.6 4.6 5 0 0 5 5 5 1 Importin repeat HEAT_EZ PF13513.6 CCH60500.1 - 9.7e-21 73.9 5.0 6.4e-11 42.5 0.1 6.6 6 0 0 6 6 5 2 HEAT-like repeat Importin_rep_5 PF18816.1 CCH60500.1 - 8.3e-19 67.6 0.9 3.6e-18 65.6 0.1 2.7 2 0 0 2 2 2 1 Importin repeat HEAT PF02985.22 CCH60500.1 - 4.3e-15 54.5 3.8 0.0012 18.9 0.0 8.0 8 0 0 8 8 7 3 HEAT repeat HEAT_2 PF13646.6 CCH60500.1 - 1.1e-13 51.4 0.0 8.3e-06 26.1 0.0 5.5 3 1 2 5 5 5 4 HEAT repeats RIX1 PF08167.12 CCH60500.1 - 2.8e-09 37.0 13.7 0.00091 19.0 0.2 6.1 5 2 1 6 6 6 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 CCH60500.1 - 5.9e-08 32.9 10.3 0.021 14.8 0.4 5.8 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCH60500.1 - 1.9e-06 28.4 2.5 0.021 15.4 0.0 6.3 4 2 4 8 8 8 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CCH60500.1 - 2.2e-05 24.7 7.9 0.0004 20.6 0.1 3.9 4 1 1 5 5 5 1 Parkin co-regulated protein DNA_alkylation PF08713.11 CCH60500.1 - 4.8e-05 23.2 0.1 0.0017 18.1 0.0 3.4 4 0 0 4 4 4 1 DNA alkylation repair enzyme MMS19_C PF12460.8 CCH60500.1 - 0.00047 19.4 3.3 0.00047 19.4 3.3 4.4 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal Arm PF00514.23 CCH60500.1 - 0.00052 20.0 4.9 5.4 7.2 0.1 5.6 5 0 0 5 5 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CCH60500.1 - 0.0026 17.3 6.5 0.16 11.5 0.2 4.8 3 2 1 4 4 4 1 CLASP N terminal UNC45-central PF11701.8 CCH60500.1 - 0.003 17.5 9.1 0.28 11.2 0.4 4.8 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central DUF3385 PF11865.8 CCH60500.1 - 0.0032 17.4 16.3 0.072 13.0 0.3 6.7 6 2 1 7 7 7 2 Domain of unknown function (DUF3385) IFRD PF05004.13 CCH60500.1 - 0.0048 16.0 8.0 0.4 9.7 0.1 3.8 4 1 0 4 4 4 2 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 CCH60500.1 - 0.013 15.7 0.7 51 4.1 0.1 4.5 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec23_helical PF04815.15 CCH60500.1 - 0.072 12.9 0.5 24 4.8 0.0 3.7 3 0 0 3 3 3 0 Sec23/Sec24 helical domain Telomere_reg-2 PF10193.9 CCH60500.1 - 3.8 8.0 8.3 42 4.6 0.6 4.2 4 0 0 4 4 4 0 Telomere length regulation protein ABC_membrane PF00664.23 CCH60501.1 - 1.3e-68 231.6 30.4 3.6e-45 154.7 11.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCH60501.1 - 5.2e-46 156.6 3.6 3.5e-28 98.8 0.1 3.8 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CCH60501.1 - 4.8e-10 39.2 12.0 0.0063 16.0 0.2 4.5 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCH60501.1 - 2.2e-09 37.6 4.6 0.02 14.7 0.1 4.5 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH60501.1 - 8.3e-07 28.7 0.2 0.05 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 CCH60501.1 - 2.5e-06 28.1 0.4 0.25 11.9 0.0 4.2 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 CCH60501.1 - 1.1e-05 25.4 0.2 0.037 13.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CCH60501.1 - 1.3e-05 25.8 0.7 0.0028 18.2 0.0 3.6 2 1 1 3 3 2 2 AAA domain AAA_22 PF13401.6 CCH60501.1 - 0.0001 22.6 2.7 1.3 9.3 0.1 3.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CCH60501.1 - 0.00012 21.9 0.5 0.63 9.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CCH60501.1 - 0.00014 21.9 0.3 0.0097 16.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 CCH60501.1 - 0.00015 20.9 0.0 0.18 10.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 CCH60501.1 - 0.00068 20.1 0.1 0.16 12.3 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.19 CCH60501.1 - 0.0013 18.4 4.1 0.15 11.7 0.1 3.0 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 CCH60501.1 - 0.0015 18.4 1.5 4.3 7.0 0.0 3.8 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 CCH60501.1 - 0.0022 17.8 0.3 3.1 7.5 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CCH60501.1 - 0.0026 17.7 0.9 2.1 8.2 0.0 3.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CCH60501.1 - 0.0077 15.8 0.1 0.085 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCH60501.1 - 0.0095 15.5 0.2 1.3 8.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region DEAD PF00270.29 CCH60501.1 - 0.021 14.6 0.6 12 5.6 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase NB-ARC PF00931.22 CCH60501.1 - 0.033 13.4 1.5 0.83 8.8 0.3 3.3 2 1 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CCH60501.1 - 0.05 14.0 0.1 7.8 6.9 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 CCH60501.1 - 0.059 13.4 0.8 15 5.7 0.0 3.5 2 1 1 3 3 3 0 AAA domain Dynamin_N PF00350.23 CCH60501.1 - 0.13 12.3 11.1 0.55 10.3 0.0 4.2 4 0 0 4 4 4 0 Dynamin family DUF87 PF01935.17 CCH60501.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.3 3 0 0 3 3 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 CCH60501.1 - 0.2 11.6 1.7 11 5.9 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_28 PF13521.6 CCH60501.1 - 0.39 11.0 3.9 2 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain Eapp_C PF10238.9 CCH60501.1 - 0.49 10.5 3.4 0.44 10.6 0.1 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein RPA43_OB PF17875.1 CCH60501.1 - 2.6 8.7 6.7 22 5.7 1.0 2.5 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I eIF-3c_N PF05470.12 CCH60502.1 - 3.9e-154 514.2 28.1 4.8e-125 418.2 9.7 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CCH60502.1 - 2.2e-11 44.2 5.1 9e-11 42.2 2.5 3.4 2 1 0 2 2 2 1 PCI domain DUF1815 PF08844.10 CCH60502.1 - 0.044 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Terminase_4 PF05119.12 CCH60502.1 - 0.17 12.3 1.8 17 6.0 0.6 2.9 2 0 0 2 2 2 0 Phage terminase, small subunit DUF4209 PF13910.6 CCH60502.1 - 1 9.6 3.9 37 4.6 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4209) AAA_21 PF13304.6 CCH60502.1 - 2.3 8.0 10.1 0.23 11.2 4.6 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Glyco_hydro_17 PF00332.18 CCH60503.1 - 2e-92 310.2 3.2 2.3e-92 310.0 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltrn_RNA_3 PF02598.17 CCH60504.1 - 2.5e-76 257.0 0.0 3.2e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.14 CCH60505.1 - 8.4e-24 84.8 21.6 8.4e-24 84.8 21.6 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SURF4 PF02077.15 CCH60506.1 - 2.1e-101 339.0 13.9 2.5e-101 338.8 13.9 1.1 1 0 0 1 1 1 1 SURF4 family TcdB_N PF12918.7 CCH60506.1 - 0.029 14.6 0.6 0.029 14.6 0.6 1.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF2207 PF09972.9 CCH60506.1 - 8.1 5.1 15.4 1.1 7.9 2.6 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) RAC_head PF16717.5 CCH60507.1 - 1.7e-17 64.2 8.5 1.7e-17 64.2 8.5 3.3 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 CCH60507.1 - 3.5e-15 55.9 0.2 1.5e-14 53.9 0.2 2.2 1 0 0 1 1 1 1 DnaJ domain EFG_II PF14492.6 CCH60507.1 - 0.097 12.8 0.5 0.26 11.4 0.5 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II DEPP PF15343.6 CCH60507.1 - 0.51 10.4 9.6 0.82 9.7 8.6 1.8 2 0 0 2 2 2 0 Decidual protein induced by progesterone family ELP6 PF09807.9 CCH60508.1 - 0.011 15.1 0.0 0.04 13.3 0.0 1.6 1 1 1 2 2 2 0 Elongation complex protein 6 DUF3336 PF11815.8 CCH60509.1 - 8.6e-30 103.3 0.3 1.6e-29 102.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCH60509.1 - 5.2e-07 30.1 0.1 9.5e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Proteasome PF00227.26 CCH60510.1 - 3.8e-42 143.9 0.0 4.5e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH60510.1 - 3.5e-11 42.5 0.1 8.2e-11 41.4 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Telomere_Sde2_2 PF13297.6 CCH60510.1 - 0.025 14.2 0.1 0.058 13.0 0.1 1.6 1 0 0 1 1 1 0 Telomere stability C-terminal RTA1 PF04479.13 CCH60511.1 - 1.6e-51 174.8 18.2 2e-51 174.6 18.2 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2214 PF09980.9 CCH60511.1 - 0.0097 15.7 1.1 0.019 14.8 1.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2214) DPM3 PF08285.11 CCH60511.1 - 3.7 7.8 5.6 1.4 9.2 0.1 2.5 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RTA1 PF04479.13 CCH60512.1 - 3.5e-56 190.1 16.6 6.5e-56 189.2 16.6 1.4 1 0 0 1 1 1 1 RTA1 like protein Orthoreo_P10 PF07204.11 CCH60512.1 - 0.00036 20.4 0.2 0.021 14.8 0.1 2.5 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 MFS_1 PF07690.16 CCH60513.1 - 5.7e-33 114.3 28.7 5.7e-33 114.3 28.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CCH60513.1 - 0.0025 16.2 1.4 0.0025 16.2 1.4 2.3 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF3589 PF12141.8 CCH60514.1 - 3.1e-79 266.8 2.4 8.4e-52 176.4 0.0 2.4 1 1 1 2 2 2 2 Beta-mannosyltransferases DUF3589 PF12141.8 CCH60515.1 - 1.4e-85 287.8 6.5 1.8e-52 178.6 0.1 2.3 1 1 1 2 2 2 2 Beta-mannosyltransferases DUF3589 PF12141.8 CCH60516.1 - 2.3e-85 287.1 5.2 1.5e-52 178.8 0.0 2.4 1 1 1 2 2 2 2 Beta-mannosyltransferases ANAPC1 PF12859.7 CCH60517.1 - 0.29 11.7 1.6 0.35 11.4 0.3 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF3589 PF12141.8 CCH60518.1 - 8.6e-62 209.3 5.1 1.5e-43 149.2 0.0 2.6 1 1 0 2 2 2 2 Beta-mannosyltransferases DUF3589 PF12141.8 CCH60519.1 - 1.9e-71 241.2 14.0 7.1e-51 173.3 0.0 3.3 3 1 0 3 3 3 2 Beta-mannosyltransferases DUF3589 PF12141.8 CCH60520.1 - 2.2e-82 277.3 3.9 3.3e-54 184.3 0.0 2.3 2 1 0 2 2 2 2 Beta-mannosyltransferases DUF2463 PF09591.10 CCH60520.1 - 0.0071 16.2 1.8 0.013 15.4 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2463) Oxidored_FMN PF00724.20 CCH60521.1 - 2.9e-89 299.7 0.0 3.3e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCH60521.1 - 0.0078 16.4 0.1 2.4 8.4 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5442) DUF3589 PF12141.8 CCH60522.1 - 8.8e-85 285.1 6.5 1.7e-56 191.8 0.0 2.3 2 1 0 2 2 2 2 Beta-mannosyltransferases Asp PF00026.23 CCH60524.1 - 3e-71 240.4 0.7 6e-71 239.4 0.0 1.8 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH60524.1 - 7.4e-10 39.3 0.5 7.4e-10 39.3 0.5 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CCH60524.1 - 0.033 14.8 1.0 16 6.2 0.1 3.5 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 CCH60524.1 - 0.59 10.7 3.4 29 5.3 0.1 3.9 5 0 0 5 5 5 0 gag-polyprotein putative aspartyl protease PIR PF00399.19 CCH60525.1 - 1.1e-41 139.6 67.8 4.5e-09 35.6 3.5 6.3 5 1 1 6 6 6 5 Yeast PIR protein repeat Oxidored_FMN PF00724.20 CCH60526.1 - 4e-114 381.4 0.0 4.8e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCH60526.1 - 0.032 14.4 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5442) DUF2401 PF10287.9 CCH60527.1 - 5.9e-63 212.5 0.0 8e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCH60527.1 - 1.9e-19 69.8 0.1 7e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) PS_Dcarbxylase PF02666.15 CCH60528.1 - 2.3e-68 229.7 0.0 4.3e-68 228.8 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase bZIP_1 PF00170.21 CCH60529.1 - 8.8e-07 28.9 1.1 1.7e-06 28.0 1.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCH60529.1 - 0.004 17.2 2.6 0.004 17.2 2.6 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 CCH60529.1 - 0.012 16.0 0.1 0.065 13.7 0.1 2.3 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Phage_T7_Capsid PF05396.11 CCH60529.1 - 0.2 12.0 1.3 1.7 9.0 0.4 2.4 2 0 0 2 2 2 0 Phage T7 capsid assembly protein GTP_EFTU PF00009.27 CCH60530.1 - 7.1e-57 192.1 0.0 1.4e-56 191.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCH60530.1 - 4.6e-13 49.0 0.0 1.4e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCH60530.1 - 2.6e-10 40.5 0.1 8.8e-10 38.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCH60530.1 - 3.9e-07 30.1 0.0 1.2e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CCH60530.1 - 0.0035 17.1 0.3 0.037 13.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CCH60530.1 - 0.0089 16.1 0.1 0.043 13.9 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ogr_Delta PF04606.12 CCH60531.1 - 0.0044 17.0 2.1 0.051 13.6 2.1 2.2 1 1 0 1 1 1 1 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 CCH60531.1 - 0.0064 16.8 0.4 0.0079 16.6 0.4 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar TRAF6_Z2 PF18048.1 CCH60531.1 - 0.095 12.8 2.6 3.7 7.7 1.8 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2 PF00096.26 CCH60531.1 - 0.22 12.1 2.0 0.71 10.5 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH60531.1 - 0.29 12.1 2.4 4.7 8.3 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 CCH60532.1 - 3.5e-61 206.9 0.5 1.1e-41 143.0 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60532.1 - 4.4e-27 95.0 1.2 1.3e-20 73.8 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH60532.1 - 2.5e-05 23.4 0.4 2.5e-05 23.4 0.4 2.7 2 1 1 3 3 3 1 Haspin like kinase domain APH PF01636.23 CCH60532.1 - 0.0023 17.9 0.1 0.73 9.7 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCH60532.1 - 0.0028 17.0 0.1 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCH60532.1 - 0.045 13.0 0.2 0.16 11.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CCH60532.1 - 0.058 12.2 0.0 0.058 12.2 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase A_deaminase PF00962.22 CCH60534.1 - 3.9e-81 272.9 0.0 4.5e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Cpn60_TCP1 PF00118.24 CCH60534.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family UPF0492 PF15744.5 CCH60534.1 - 0.21 10.7 0.1 0.39 9.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 Pkinase PF00069.25 CCH60535.1 - 3.5e-24 85.6 0.0 3.5e-24 85.6 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60535.1 - 7e-12 45.2 0.1 1.8e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH60535.1 - 2.2e-08 33.3 0.0 2.2e-08 33.3 0.0 3.0 2 1 0 2 2 2 1 Fungal protein kinase zf-AN1 PF01428.16 CCH60536.1 - 4.3e-11 42.8 12.0 7.5e-11 42.0 12.0 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger zf-CRD PF17979.1 CCH60536.1 - 0.92 9.6 7.8 4 7.5 7.8 2.0 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Pga1 PF10333.9 CCH60538.1 - 5.9e-22 78.3 12.3 3.8e-20 72.5 12.3 2.1 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator DUF2009 PF09418.10 CCH60539.1 - 2.3e-196 653.3 7.0 3e-196 652.9 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CCH60539.1 - 1.6e-06 28.2 7.0 3.1e-06 27.2 7.0 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CCH60539.1 - 0.19 12.0 8.8 0.061 13.6 5.2 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain PGA2 PF07543.12 CCH60540.1 - 1.1e-16 61.0 6.9 8.9e-12 45.2 0.7 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 DUF4574 PF15141.6 CCH60540.1 - 0.0042 16.9 1.0 0.0061 16.4 0.2 1.6 1 1 1 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Ly49 PF08391.10 CCH60540.1 - 0.094 13.1 0.7 0.12 12.7 0.7 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region OSTbeta PF15048.6 CCH60540.1 - 0.18 12.0 4.1 0.71 10.0 4.1 1.7 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein DUF5132 PF17195.4 CCH60540.1 - 0.26 11.4 4.6 6 7.1 1.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) COX16 PF14138.6 CCH60540.1 - 0.37 11.3 3.4 0.89 10.1 3.4 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Phage_Gp23 PF10669.9 CCH60540.1 - 1.4 9.2 12.6 5.1 7.4 12.6 1.8 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RNA_pol_3_Rpc31 PF11705.8 CCH60541.1 - 7.5e-54 183.4 11.5 9.5e-54 183.0 11.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 THOC2_N PF16134.5 CCH60542.1 - 6.2e-134 448.0 16.3 1.4e-133 446.9 16.3 1.5 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CCH60542.1 - 9.3e-37 126.8 5.8 9.3e-37 126.8 5.8 5.4 4 1 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CCH60542.1 - 1.2e-19 70.1 0.4 7e-19 67.7 0.2 2.6 2 0 0 2 2 2 1 Transcription- and export-related complex subunit SF3b10 PF07189.11 CCH60543.1 - 3.2e-26 91.3 1.4 4.1e-26 90.9 1.4 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Nefa_Nip30_N PF10187.9 CCH60544.1 - 7.5e-08 32.7 12.8 1.3e-07 31.9 12.8 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 NDT80_PhoG PF05224.12 CCH60545.1 - 7.8e-61 205.5 0.8 7.8e-61 205.5 0.8 2.3 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.6 CCH60546.1 - 4.7e-99 330.4 0.0 1.7e-98 328.6 0.0 2.0 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CCH60546.1 - 1.8e-91 306.0 9.2 3.4e-91 305.2 9.2 1.5 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CCH60546.1 - 7.7e-66 221.3 0.0 3.8e-65 219.0 0.0 2.2 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 CCH60546.1 - 2.3e-34 117.2 0.0 7.2e-34 115.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 CCH60546.1 - 0.014 15.6 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Sigma70_r4_2 PF08281.12 CCH60546.1 - 0.021 14.5 0.1 0.51 10.1 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 DEAD PF00270.29 CCH60546.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Tom22 PF04281.13 CCH60547.1 - 1.7e-45 154.2 0.5 1.9e-45 154.0 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 RRN3 PF05327.11 CCH60547.1 - 0.46 9.0 3.6 0.5 8.9 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 CCH60547.1 - 3.1 8.2 13.2 5.3 7.5 13.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 CCH60547.1 - 4.1 6.4 12.9 5.4 6.0 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CCH60547.1 - 8.5 5.6 13.3 11 5.2 13.3 1.2 1 0 0 1 1 1 0 NOA36 protein CDP-OH_P_transf PF01066.21 CCH60548.1 - 1.8e-16 60.6 0.1 1.8e-16 60.6 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase dNK PF01712.19 CCH60549.1 - 0.00034 20.5 0.4 0.64 9.8 0.0 2.6 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_18 PF13238.6 CCH60549.1 - 0.0017 18.9 1.0 0.015 15.8 1.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCH60549.1 - 0.0044 17.3 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CCH60549.1 - 0.013 15.2 0.3 0.059 13.1 0.3 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NUP214 PF16755.5 CCH60549.1 - 0.041 13.1 0.2 0.054 12.7 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 CPT PF07931.12 CCH60549.1 - 0.06 13.2 0.0 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein T2SSE PF00437.20 CCH60549.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 CCH60549.1 - 0.18 11.7 0.3 10 6.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF5344 PF17279.2 CCH60549.1 - 0.74 10.4 3.1 0.55 10.8 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5344) AD PF09793.9 CCH60550.1 - 1.3e-09 38.0 0.2 4.5e-09 36.3 0.1 1.9 2 1 0 2 2 2 1 Anticodon-binding domain LSM14 PF12701.7 CCH60550.1 - 0.048 13.8 0.2 0.097 12.8 0.2 1.5 1 0 0 1 1 1 0 Scd6-like Sm domain N1221 PF07923.13 CCH60551.1 - 1.5e-71 240.9 4.7 1.5e-71 240.9 4.7 2.2 2 0 0 2 2 2 1 N1221-like protein DUF3402 PF11882.8 CCH60551.1 - 1.9e-58 198.7 12.7 1.4e-37 130.0 5.4 3.5 2 2 2 4 4 4 2 Domain of unknown function (DUF3402) DUF5470 PF17564.2 CCH60551.1 - 0.35 11.1 2.0 3.6 7.9 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Mak16 PF04874.14 CCH60551.1 - 5.8 7.6 12.7 0.57 10.8 4.6 2.8 2 0 0 2 2 2 0 Mak16 protein C-terminal region PI3_PI4_kinase PF00454.27 CCH60552.1 - 7.4e-50 170.1 0.1 3.4e-49 167.9 0.1 2.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CCH60552.1 - 3e-27 95.6 4.5 3e-27 95.6 4.5 4.2 5 0 0 5 5 5 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CCH60552.1 - 2.6e-12 46.3 0.0 5.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 FATC domain Ribosomal_L14 PF00238.19 CCH60553.1 - 7.4e-34 116.5 0.0 8.7e-34 116.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4_3 PF13920.6 CCH60554.1 - 9.7e-10 38.2 6.8 1.6e-09 37.5 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH60554.1 - 2.3e-08 33.8 7.4 4.1e-08 33.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH60554.1 - 8.7e-08 32.1 6.0 1.7e-07 31.1 6.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCH60554.1 - 3.7e-07 29.9 8.2 4.8e-06 26.3 8.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH60554.1 - 4.6e-07 30.1 8.3 7.8e-07 29.3 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCH60554.1 - 1.2e-05 25.2 8.5 2.1e-05 24.4 8.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCH60554.1 - 2.4e-05 24.1 7.7 5e-05 23.1 7.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCH60554.1 - 0.00046 20.3 7.2 0.00088 19.4 7.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CCH60554.1 - 0.0079 16.2 3.7 0.013 15.6 3.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCH60554.1 - 0.13 12.6 7.2 0.42 10.9 7.2 1.9 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CCH60554.1 - 1.5 8.6 7.6 0.41 10.4 3.7 2.1 2 0 0 2 2 2 0 RING-like zinc finger PH PF00169.29 CCH60555.1 - 1.4e-13 51.3 0.4 4.9e-13 49.5 0.4 2.0 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 CCH60555.1 - 4.2e-11 42.3 0.0 1.1e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH60555.1 - 1e-08 34.9 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 CCH60555.1 - 6.7e-06 26.1 0.6 1.9e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) CRF PF00473.17 CCH60555.1 - 0.015 15.4 0.3 0.073 13.2 0.3 2.2 2 0 0 2 2 2 0 Corticotropin-releasing factor family SAM_1 PF00536.30 CCH60555.1 - 0.32 11.5 1.3 0.41 11.1 0.2 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) TPR_2 PF07719.17 CCH60556.1 - 9.4e-28 94.1 11.8 2.7e-07 30.2 0.2 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CCH60556.1 - 9.5e-28 94.9 15.1 3.2e-09 36.2 0.8 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCH60556.1 - 1.2e-23 81.3 14.7 3.9e-05 23.5 0.3 8.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 CCH60556.1 - 6.4e-18 64.2 11.1 0.0012 18.5 0.0 5.9 3 2 3 6 6 6 5 TPR repeat TPR_12 PF13424.6 CCH60556.1 - 1.4e-17 63.7 1.0 0.00045 20.4 0.2 6.2 4 1 3 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH60556.1 - 1e-13 51.3 27.6 4.5e-05 23.6 2.9 5.5 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CCH60556.1 - 2.1e-13 49.6 19.5 2e-07 30.9 0.7 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCH60556.1 - 1.4e-12 46.7 0.4 0.0096 15.9 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH60556.1 - 5.6e-12 46.0 0.7 8e-05 23.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCH60556.1 - 3.9e-11 43.4 0.0 4.9e-05 23.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH60556.1 - 1.1e-10 41.4 0.0 0.84 10.6 0.0 6.0 2 1 4 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCH60556.1 - 9.3e-08 32.2 13.3 0.081 13.6 0.5 7.2 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCH60556.1 - 9.5e-06 25.7 0.0 0.048 13.8 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 CCH60556.1 - 0.0002 20.7 0.0 0.059 12.6 0.1 3.7 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCH60556.1 - 0.0053 16.6 3.3 2.8 7.9 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Sel1 PF08238.12 CCH60556.1 - 0.014 16.1 2.7 31 5.4 0.0 4.4 4 0 0 4 4 3 0 Sel1 repeat SRP_TPR_like PF17004.5 CCH60556.1 - 0.032 14.3 0.0 0.032 14.3 0.0 3.9 4 2 1 5 5 5 0 Putative TPR-like repeat RF3_C PF16658.5 CCH60556.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain NMT PF01233.19 CCH60556.1 - 0.064 13.1 1.7 3 7.6 0.1 2.7 2 1 1 3 3 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain TPR_20 PF14561.6 CCH60556.1 - 0.096 13.0 0.0 4.1 7.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Phospholamban PF04272.14 CCH60556.1 - 0.26 10.8 1.9 0.35 10.4 0.1 2.2 2 0 0 2 2 1 0 Phospholamban Fis1_TPR_C PF14853.6 CCH60556.1 - 8.2 6.6 10.5 4 7.6 0.2 4.6 4 1 2 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat Ank_4 PF13637.6 CCH60558.1 - 9.7e-08 32.4 3.3 0.0054 17.3 0.9 3.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCH60558.1 - 1.1e-07 32.3 1.8 0.0093 16.5 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 CCH60558.1 - 6.3e-06 26.0 1.1 6.3e-06 26.0 1.1 6.2 4 2 1 5 5 5 1 KilA-N domain Ank_5 PF13857.6 CCH60558.1 - 8.6e-06 25.9 2.6 0.017 15.4 0.3 3.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH60558.1 - 2.4e-05 24.4 5.2 0.0066 16.9 0.3 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CCH60558.1 - 6.7e-05 23.2 6.1 0.035 14.6 0.7 4.2 4 0 0 4 4 4 2 Ankyrin repeat HEAT_EZ PF13513.6 CCH60559.1 - 7.7e-16 58.2 0.1 0.066 13.7 0.0 8.3 7 1 1 8 8 7 4 HEAT-like repeat IBN_N PF03810.19 CCH60559.1 - 3.3e-14 52.6 8.9 1.1e-10 41.3 1.0 4.7 4 0 0 4 4 4 2 Importin-beta N-terminal domain HEAT PF02985.22 CCH60559.1 - 8.8e-12 44.2 3.6 0.047 14.0 0.0 8.3 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 CCH60559.1 - 1.4e-06 28.6 3.9 5.3 7.5 0.3 6.7 6 2 2 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.7 CCH60559.1 - 5.1e-05 23.8 5.4 4.4 8.0 0.0 6.7 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CCH60559.1 - 0.00063 19.8 4.8 2.9 7.9 0.2 5.2 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 G-alpha PF00503.20 CCH60559.1 - 0.0048 16.1 0.1 0.012 14.8 0.1 1.7 1 0 0 1 1 1 1 G-protein alpha subunit PLN_propep PF16485.5 CCH60559.1 - 0.02 14.6 0.1 0.062 13.0 0.0 1.9 2 0 0 2 2 2 0 Protealysin propeptide Tti2 PF10521.9 CCH60559.1 - 0.022 14.3 0.5 0.34 10.4 0.0 3.2 3 1 0 3 3 3 0 Tti2 family PAD_M PF08527.10 CCH60559.1 - 0.025 14.2 0.2 0.068 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Arm PF00514.23 CCH60559.1 - 0.041 13.9 3.9 16 5.7 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Xpo1 PF08389.12 CCH60559.1 - 0.049 13.7 3.2 0.61 10.1 0.1 4.6 4 1 0 5 5 5 0 Exportin 1-like protein RTP1_C1 PF10363.9 CCH60559.1 - 0.16 12.1 0.9 2.1 8.5 0.1 3.4 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 CCH60559.1 - 0.22 11.4 7.3 9.9 6.0 0.0 6.1 6 2 0 6 6 6 0 Domain of unknown function (DUF3385) SapB_2 PF03489.17 CCH60559.1 - 5.1 7.3 5.4 53 4.0 0.2 4.5 5 0 0 5 5 5 0 Saposin-like type B, region 2 ALG3 PF05208.13 CCH60560.1 - 3.4e-127 424.8 28.0 4.5e-127 424.4 28.0 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.11 CCH60561.1 - 6.6e-08 32.2 0.3 1.6e-07 31.0 0.3 1.7 1 0 0 1 1 1 1 LisH CYSTM PF12734.7 CCH60561.1 - 8.4 6.8 6.9 52 4.3 6.9 2.5 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF5349 PF17298.2 CCH60562.1 - 4.4e-26 92.5 76.6 1.7e-14 54.4 57.2 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5349) GatB_N PF02934.15 CCH60563.1 - 1.7e-88 296.6 0.0 2.2e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CCH60563.1 - 1e-18 67.6 0.0 1.9e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 GatB domain Nucleoporin_N PF08801.11 CCH60564.1 - 4e-123 411.4 12.1 4e-123 411.4 12.1 3.7 4 0 0 4 4 4 2 Nup133 N terminal like Nucleoporin_C PF03177.14 CCH60564.1 - 1.1e-122 410.8 25.7 2.9e-122 409.4 25.7 1.7 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal G10 PF01125.17 CCH60564.1 - 0.17 11.6 0.3 0.47 10.2 0.3 1.7 1 0 0 1 1 1 0 G10 protein HSP70 PF00012.20 CCH60565.1 - 5.6e-258 857.1 5.8 6.3e-258 856.9 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH60565.1 - 7.2e-17 61.2 0.1 6.6e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCH60565.1 - 0.00046 20.0 0.0 0.0009 19.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CCH60565.1 - 0.026 14.0 0.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 CCH60565.1 - 0.058 12.4 0.6 0.35 9.8 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain OTCace_N PF02729.21 CCH60565.1 - 0.075 13.1 0.2 0.21 11.6 0.2 1.7 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Hydantoinase_A PF01968.18 CCH60565.1 - 0.11 11.7 0.2 0.26 10.5 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Golgin_A5 PF09787.9 CCH60565.1 - 2.1 7.7 7.7 1.1 8.6 3.6 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 AAR2 PF05282.11 CCH60566.1 - 2.5e-14 53.5 5.1 2.4e-13 50.2 5.1 1.9 1 1 0 1 1 1 1 AAR2 protein DUF4893 PF16233.5 CCH60566.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) DUF1765 PF08578.10 CCH60566.1 - 1.2 9.6 5.7 4.8 7.7 2.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) UQ_con PF00179.26 CCH60567.1 - 2.6e-21 75.7 0.1 4e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCH60567.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CCH60567.1 - 0.41 10.9 2.4 0.47 10.8 0.2 2.0 1 1 1 2 2 2 0 RWD domain Pribosyltran_N PF13793.6 CCH60568.1 - 3.5e-41 139.8 0.3 3.4e-39 133.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCH60568.1 - 3.6e-36 124.9 2.6 2.6e-30 105.8 0.4 2.4 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCH60568.1 - 1.2e-16 60.6 0.6 3.6e-16 59.1 0.6 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCH60568.1 - 0.0063 16.0 0.1 0.01 15.3 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UCH PF00443.29 CCH60569.1 - 1.6e-57 194.9 20.8 1.6e-57 194.9 20.8 3.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH60569.1 - 5e-10 39.5 32.4 5e-10 39.5 32.4 5.7 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Cytidylate_kin2 PF13189.6 CCH60569.1 - 0.029 14.5 0.8 0.073 13.2 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family Zn_clus PF00172.18 CCH60570.1 - 2.5e-08 33.9 12.5 4.2e-08 33.2 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.23 CCH60571.1 - 5.8e-100 334.5 12.1 5.8e-100 334.5 12.1 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CCH60571.1 - 4.2e-25 88.4 1.9 4.2e-25 88.4 1.9 3.7 3 1 0 3 3 3 1 Microtubule binding YebO PF13974.6 CCH60571.1 - 0.029 14.4 0.3 0.029 14.4 0.3 2.4 2 0 0 2 2 2 0 YebO-like protein DUF2120 PF09893.9 CCH60571.1 - 0.24 11.5 0.1 0.24 11.5 0.1 8.0 4 1 3 10 10 10 0 Uncharacterized protein conserved in archaea (DUF2120) DUF3636 PF12331.8 CCH60571.1 - 1.4 8.8 7.7 2.5 7.9 0.2 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3636) zf-RING_2 PF13639.6 CCH60572.1 - 6.1e-06 26.5 7.3 6.1e-06 26.5 7.3 2.2 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 CCH60572.1 - 2.4e-05 24.4 5.7 9.3e-05 22.5 5.7 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CCH60572.1 - 0.00018 21.7 6.9 0.00041 20.6 6.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCH60572.1 - 0.00044 20.2 1.7 0.00095 19.2 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CCH60572.1 - 0.03 14.2 5.4 7.2 6.6 5.5 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CCH60572.1 - 0.08 13.3 7.3 0.16 12.3 7.3 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 CCH60572.1 - 0.097 12.8 5.8 0.2 11.8 5.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 CCH60572.1 - 0.099 12.5 8.1 0.26 11.2 8.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCH60572.1 - 0.13 11.9 3.3 0.29 10.8 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CCH60572.1 - 0.42 10.5 7.0 1.2 9.0 7.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CCH60572.1 - 0.63 9.9 9.0 1.5 8.7 1.1 3.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain CPL PF08144.11 CCH60572.1 - 2.4 8.5 10.9 0.27 11.6 4.8 2.6 3 0 0 3 3 2 0 CPL (NUC119) domain PHD PF00628.29 CCH60572.1 - 2.8 7.9 6.4 5.6 6.9 6.4 1.5 1 0 0 1 1 1 0 PHD-finger AMP-binding PF00501.28 CCH60573.1 - 3.8e-89 299.2 0.0 5e-89 298.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EFF-AFF PF14884.6 CCH60573.1 - 0.016 13.3 0.3 0.025 12.7 0.3 1.2 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Imm53 PF15580.6 CCH60573.1 - 0.12 12.1 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 53 Bac_rhodopsin PF01036.18 CCH60574.1 - 9.8e-49 165.9 17.1 1.6e-48 165.2 17.1 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Esterase PF00756.20 CCH60575.1 - 2.7e-49 168.1 0.0 3.3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.25 CCH60575.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 CCH60575.1 - 0.21 10.8 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Bac_rhodopsin PF01036.18 CCH60576.1 - 9.8e-44 149.6 16.6 1.2e-43 149.3 16.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4792 PF16040.5 CCH60576.1 - 0.015 15.2 0.6 0.036 14.0 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4792) Bac_rhodopsin PF01036.18 CCH60577.1 - 1.7e-45 155.3 18.0 2.2e-45 155.0 18.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Cation_efflux PF01545.21 CCH60578.1 - 1.6e-52 178.1 7.1 5.5e-52 176.4 7.1 1.7 1 1 0 1 1 1 1 Cation efflux family Pheromone PF08015.11 CCH60578.1 - 3.1 8.9 6.6 8.2 7.6 0.6 2.9 3 0 0 3 3 3 0 Fungal mating-type pheromone Serglycin PF04360.12 CCH60579.1 - 0.37 10.7 10.4 0.19 11.7 4.2 2.8 3 0 0 3 3 3 0 Serglycin Mito_carr PF00153.27 CCH60581.1 - 3.8e-28 97.2 6.6 1.3e-13 50.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5341 PF17276.2 CCH60582.1 - 3e-15 56.8 10.0 1.3e-13 51.4 10.0 2.2 1 1 0 1 1 1 1 Family of unknown function (DUF5341) TMEM156 PF15106.6 CCH60582.1 - 0.17 11.3 2.1 0.3 10.5 2.1 1.3 1 0 0 1 1 1 0 TMEM156 protein family Epimerase PF01370.21 CCH60583.1 - 5.8e-17 62.0 0.1 8.6e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCH60583.1 - 1.4e-13 50.5 0.3 2e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CCH60583.1 - 3.7e-10 39.7 0.0 1.6e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCH60583.1 - 3.2e-09 36.9 0.1 8.3e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CCH60583.1 - 8.2e-09 35.0 0.3 8.7e-08 31.6 0.3 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CCH60583.1 - 4.8e-08 32.5 0.8 9.9e-08 31.5 0.4 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCH60583.1 - 5.5e-07 29.4 0.1 0.00025 20.7 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 CCH60583.1 - 4e-06 26.4 0.1 9.6e-06 25.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCH60583.1 - 0.00025 21.0 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CCH60583.1 - 0.001 18.3 0.1 0.0025 17.0 0.1 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short_C2 PF13561.6 CCH60583.1 - 0.033 13.7 0.1 0.066 12.8 0.1 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DapB_N PF01113.20 CCH60583.1 - 0.1 12.7 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RIIa PF02197.17 CCH60583.1 - 0.17 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit MFS_1 PF07690.16 CCH60584.1 - 3.3e-19 69.0 50.5 3.2e-18 65.8 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CCH60585.1 - 2.1e-22 79.5 44.7 3.8e-20 72.1 26.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_C_37 PF18665.1 CCH60585.1 - 0.045 14.4 0.5 0.17 12.5 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TraS PF10624.9 CCH60585.1 - 0.43 10.5 5.1 0.33 10.9 2.4 2.1 1 1 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF382 PF04037.13 CCH60587.1 - 6.9e-48 162.0 5.4 9.6e-48 161.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 CCH60587.1 - 8.1e-19 67.2 3.3 8.1e-19 67.2 3.3 1.8 2 0 0 2 2 2 1 PSP DUF1151 PF06625.11 CCH60587.1 - 0.019 14.9 9.9 0.046 13.7 9.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) DUF1992 PF09350.10 CCH60587.1 - 0.054 13.7 0.1 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) SNF2_N PF00176.23 CCH60588.1 - 1.1e-75 254.6 0.7 3.1e-75 253.1 0.7 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCH60588.1 - 6.8e-38 129.2 4.7 6.8e-38 129.2 4.7 3.2 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 CCH60588.1 - 3.7e-34 117.8 12.1 3.7e-34 117.8 12.1 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 CCH60588.1 - 6.3e-20 71.6 0.1 1.3e-18 67.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH60588.1 - 3.4e-12 46.7 0.0 3.4e-12 46.7 0.0 3.9 3 2 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCH60588.1 - 2.5e-05 24.1 0.2 8.5e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1086 PF06461.11 CCH60588.1 - 0.086 12.7 0.2 0.086 12.7 0.2 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) SNO PF01174.19 CCH60588.1 - 0.12 12.2 0.3 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 SNO glutamine amidotransferase family YhzD PF14120.6 CCH60588.1 - 0.48 10.6 5.8 3.9 7.6 0.5 4.2 4 0 0 4 4 4 0 YhzD-like protein AAA_14 PF13173.6 CCH60588.1 - 0.88 9.6 4.3 0.43 10.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain RCC1 PF00415.18 CCH60589.1 - 3.1e-24 85.3 0.7 1.6e-09 38.3 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCH60589.1 - 1.2e-16 60.0 10.9 2.8e-08 33.3 1.3 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CCH60589.1 - 5.7e-09 36.2 2.2 3.7e-05 23.9 0.2 2.9 2 0 0 2 2 2 2 BTB/POZ domain GATase PF00117.28 CCH60590.1 - 2.2e-48 164.6 0.0 3.4e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CCH60590.1 - 1.7e-45 154.0 0.0 2.8e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 CCH60590.1 - 7.5e-07 29.1 0.2 2.8e-05 24.0 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 Leader_CPA1 PF08252.11 CCH60591.1 - 1.1e-16 59.9 2.9 1.2e-16 59.8 2.9 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide RGS PF00615.19 CCH60592.1 - 1.8e-05 25.0 0.7 0.002 18.4 0.3 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF4834 PF16118.5 CCH60592.1 - 4.3 8.4 7.7 10 7.2 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) MBF1 PF08523.10 CCH60593.1 - 2.6e-23 82.2 1.6 2.6e-23 82.2 1.6 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CCH60593.1 - 2e-14 53.4 0.4 3.5e-14 52.6 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CCH60593.1 - 1.8e-06 28.2 0.0 3.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CCH60593.1 - 0.00041 20.3 0.2 0.0007 19.6 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 CCH60593.1 - 0.11 12.6 0.1 0.19 11.8 0.1 1.3 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA LRR_6 PF13516.6 CCH60594.1 - 9.5e-08 31.5 10.7 0.96 9.7 0.1 7.9 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CCH60594.1 - 0.00014 21.9 7.2 55 4.9 0.0 7.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 CCH60594.1 - 0.0013 19.1 31.3 0.4 11.2 0.3 7.3 5 3 3 9 9 9 3 Leucine Rich repeats (2 copies) Myc_N PF01056.18 CCH60594.1 - 0.91 9.4 6.8 1.3 8.8 6.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DNA_pol_phi PF04931.13 CCH60594.1 - 5.4 5.0 18.0 7.9 4.4 18.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CCH60594.1 - 6.9 7.1 14.4 16 6.0 14.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CybS PF05328.12 CCH60595.1 - 2.3e-44 150.3 0.1 3e-44 149.9 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cauli_VI PF01693.16 CCH60596.1 - 4e-31 107.1 9.1 4e-19 68.6 2.1 2.8 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 CCH60596.1 - 1.2e-29 103.3 1.2 3.1e-29 102.0 1.2 1.7 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 CCH60596.1 - 0.033 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Macin PF14865.6 CCH60596.1 - 0.045 14.3 9.2 0.18 12.3 0.8 3.1 3 0 0 3 3 3 0 Macin Membr_traf_MHD PF10540.9 CCH60597.1 - 1.5e-37 129.1 3.0 3.8e-37 127.8 0.0 3.1 3 0 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CCH60597.1 - 4.1e-08 33.4 0.0 9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 CCH60597.1 - 3.2e-05 22.7 1.9 5.6e-05 21.9 0.4 1.9 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) CCM2_C PF16545.5 CCH60597.1 - 0.0081 16.7 2.2 0.52 10.9 0.0 3.2 3 0 0 3 3 3 1 Cerebral cavernous malformation protein, harmonin-homology DnaB_2 PF07261.11 CCH60597.1 - 0.21 11.4 2.2 33 4.3 0.1 3.9 3 0 0 3 3 3 0 Replication initiation and membrane attachment SWIB PF02201.18 CCH60598.1 - 2.7e-24 84.8 0.4 2.7e-24 84.8 0.4 2.3 2 0 0 2 2 2 1 SWIB/MDM2 domain RRS1 PF04939.12 CCH60599.1 - 2.4e-60 203.1 4.5 2.8e-60 202.9 4.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.20 CCH60600.1 - 1.2e-13 51.7 10.6 1.2e-13 51.7 10.6 3.0 2 1 0 2 2 2 1 RhoGEF domain Uds1 PF15456.6 CCH60600.1 - 0.014 15.5 4.2 0.026 14.7 2.7 2.2 2 0 0 2 2 2 0 Up-regulated During Septation FAM76 PF16046.5 CCH60600.1 - 0.79 9.0 12.4 0.18 11.1 5.1 2.3 2 0 0 2 2 2 0 FAM76 protein S10_plectin PF03501.15 CCH60601.1 - 8e-43 144.4 0.3 9.1e-43 144.3 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain PadR PF03551.14 CCH60601.1 - 0.025 14.5 0.2 0.042 13.8 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family Replic_Relax PF13814.6 CCH60601.1 - 0.031 14.4 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation DUF4364 PF14277.6 CCH60601.1 - 0.061 13.1 0.2 0.12 12.1 0.1 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) MsyB PF13984.6 CCH60601.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 MsyB protein Mpv17_PMP22 PF04117.12 CCH60602.1 - 3.5e-20 72.0 0.6 3.5e-20 72.0 0.6 2.7 3 0 0 3 3 3 1 Mpv17 / PMP22 family P5-ATPase PF12409.8 CCH60603.1 - 1.5e-34 118.8 0.1 4.9e-34 117.1 0.1 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 CCH60603.1 - 5e-29 101.1 0.0 1.4e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH60603.1 - 5.7e-11 43.1 0.1 0.00019 21.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCH60603.1 - 3.3e-05 23.5 0.0 8.4e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CCH60603.1 - 4.1e-05 23.6 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCH60603.1 - 0.19 11.5 1.2 15 5.2 0.0 3.5 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase SCAMP PF04144.13 CCH60603.1 - 0.58 10.5 15.6 1.9 8.8 5.1 2.7 1 1 1 2 2 2 0 SCAMP family S1 PF00575.23 CCH60604.1 - 1.5e-49 166.2 27.1 1.2e-10 41.5 0.9 10.2 10 0 0 10 10 9 8 S1 RNA binding domain TPR_19 PF14559.6 CCH60604.1 - 1.8e-06 28.3 0.6 0.057 13.9 0.8 3.1 2 1 2 4 4 4 3 Tetratricopeptide repeat Suf PF05843.14 CCH60604.1 - 0.00022 21.3 8.2 0.0042 17.1 3.8 4.6 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_16 PF13432.6 CCH60604.1 - 0.0004 21.0 0.0 0.11 13.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH60604.1 - 0.001 19.7 1.4 22 6.2 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CCH60604.1 - 0.0095 15.9 3.2 0.07 13.1 0.8 2.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CCH60604.1 - 0.018 15.3 0.5 9.6 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CCH60604.1 - 0.074 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain S1_2 PF13509.6 CCH60604.1 - 0.079 13.0 0.6 10 6.3 0.1 4.6 4 0 0 4 4 4 0 S1 domain PCB_OB PF17092.5 CCH60604.1 - 0.25 12.1 0.7 16 6.3 0.1 4.1 4 1 1 5 5 5 0 Penicillin-binding protein OB-like domain MIIP PF15734.5 CCH60604.1 - 0.35 10.3 11.0 0.053 13.0 1.0 2.3 2 0 0 2 2 2 0 Migration and invasion-inhibitory TPR_15 PF13429.6 CCH60604.1 - 0.79 8.9 4.1 13 4.9 3.3 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat Synuclein PF01387.17 CCH60604.1 - 0.92 9.7 8.3 0.13 12.5 0.2 3.3 3 0 0 3 3 3 0 Synuclein DUF2681 PF10883.8 CCH60605.1 - 0.17 12.3 0.1 0.17 12.3 0.1 3.7 5 1 0 5 5 5 0 Protein of unknown function (DUF2681) Pox_EPC_I2-L1 PF12575.8 CCH60605.1 - 0.21 11.8 5.0 0.17 12.1 0.2 2.7 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 TAFII55_N PF04658.13 CCH60606.1 - 1.5e-50 171.0 0.0 1.5e-50 171.0 0.0 2.9 2 1 0 2 2 2 1 TAFII55 protein conserved region SNF2_N PF00176.23 CCH60607.1 - 4.9e-73 245.9 1.1 1.6e-72 244.1 1.1 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH60607.1 - 3.3e-22 78.9 2.2 1.7e-19 70.2 0.0 3.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 CCH60607.1 - 3.6e-17 62.2 0.7 1.4e-16 60.3 0.7 2.1 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 CCH60607.1 - 3.3e-15 56.4 5.0 3.3e-15 56.4 5.0 4.6 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 CCH60607.1 - 6.2e-05 23.2 11.1 6.2e-05 23.2 11.1 4.6 4 1 0 4 4 4 1 HSA adh_short PF00106.25 CCH60608.1 - 7.7e-54 182.1 0.0 1e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH60608.1 - 5e-34 117.9 0.0 6.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH60608.1 - 7.7e-10 39.0 0.0 1e-09 38.6 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CCH60608.1 - 0.0062 15.9 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Thioredoxin PF00085.20 CCH60609.1 - 3e-22 78.6 1.2 6.5e-22 77.5 0.1 2.1 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 CCH60609.1 - 2.1e-05 24.5 8.6 0.016 15.2 2.2 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CCH60609.1 - 0.0031 18.0 3.1 0.0034 17.8 0.1 2.5 3 1 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 CCH60609.1 - 0.004 17.0 0.1 0.0083 16.0 0.0 1.5 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 CCH60609.1 - 0.0077 16.4 0.1 0.03 14.6 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_8 PF13905.6 CCH60609.1 - 0.015 15.6 0.0 0.015 15.6 0.0 3.1 2 1 0 3 3 3 0 Thioredoxin-like Redoxin PF08534.10 CCH60609.1 - 0.035 13.8 0.1 0.098 12.4 0.1 1.7 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 CCH60609.1 - 0.039 14.2 0.1 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like DSBA PF01323.20 CCH60609.1 - 0.14 11.9 0.0 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain RRP36 PF06102.12 CCH60610.1 - 3.1e-37 128.1 25.7 3.1e-37 128.1 25.7 2.4 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Rhomboid_SP PF12595.8 CCH60610.1 - 0.0055 16.1 5.2 0.011 15.1 5.2 1.5 1 0 0 1 1 1 1 Rhomboid serine protease Rhodanese PF00581.20 CCH60611.1 - 3.5e-13 50.0 0.1 6.1e-13 49.2 0.0 1.5 2 0 0 2 2 2 1 Rhodanese-like domain TetR_N PF00440.23 CCH60611.1 - 0.51 10.2 0.0 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family His_Phos_1 PF00300.22 CCH60612.1 - 1.1e-36 126.4 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mre11_DNA_bind PF04152.14 CCH60613.1 - 4.3e-49 167.1 5.0 4.3e-49 167.1 5.0 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CCH60613.1 - 3.8e-12 47.2 1.0 7.2e-12 46.2 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCH60613.1 - 0.0038 17.4 0.0 0.024 14.8 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Phosducin PF02114.16 CCH60614.1 - 1.6e-07 30.5 6.6 0.00041 19.4 0.2 2.2 1 1 0 2 2 2 2 Phosducin RUN PF02759.19 CCH60614.1 - 0.068 13.1 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 RUN domain UCH PF00443.29 CCH60615.1 - 5.2e-49 167.1 6.9 7.6e-49 166.5 6.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH60615.1 - 2.4e-16 60.2 11.4 2.4e-16 60.2 11.4 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCH60615.1 - 8.7e-12 45.2 12.6 8.7e-12 45.2 12.6 3.1 2 1 1 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein FSH1 PF03959.13 CCH60616.1 - 1.8e-59 201.0 0.0 2e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCH60616.1 - 2.1e-05 24.5 0.0 6.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase GMP_synt_C PF00958.22 CCH60618.1 - 1.8e-43 146.5 0.0 3.2e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CCH60618.1 - 8.9e-41 139.7 0.0 1.5e-40 139.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CCH60618.1 - 4.6e-08 32.5 0.0 1.4e-05 24.4 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CCH60618.1 - 9.2e-07 28.8 0.0 5.8e-06 26.2 0.0 2.3 2 1 0 2 2 2 1 Peptidase C26 QueC PF06508.13 CCH60618.1 - 0.012 15.1 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 CCH60618.1 - 0.013 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 CCH60618.1 - 0.017 14.5 0.2 0.026 13.8 0.2 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase tRNA_Me_trans PF03054.16 CCH60618.1 - 0.023 13.5 0.1 0.051 12.4 0.1 1.6 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.14 CCH60618.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Pkinase PF00069.25 CCH60619.1 - 2.7e-42 145.0 1.9 3e-20 72.7 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60619.1 - 1.3e-10 41.1 1.2 4e-06 26.3 0.5 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 CCH60620.1 - 2.4e-125 418.0 7.7 7.5e-125 416.4 6.3 1.9 2 0 0 2 2 2 1 Glucanosyltransferase Cellulase PF00150.18 CCH60620.1 - 0.00062 19.3 0.2 0.0055 16.2 0.2 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4073 PF13285.6 CCH60620.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) BRO1 PF03097.18 CCH60621.1 - 1e-66 225.4 3.9 2.2e-66 224.3 3.9 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCH60621.1 - 9.7e-11 41.5 15.8 4.1e-08 32.9 2.1 3.3 2 1 1 3 3 3 2 ALIX V-shaped domain binding to HIV CotJB PF12652.7 CCH60621.1 - 0.18 12.0 1.8 17 5.7 0.5 3.2 2 1 0 2 2 2 0 CotJB protein IPPT PF01715.17 CCH60622.1 - 4.4e-69 232.8 1.4 6.4e-69 232.2 1.4 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 CCH60622.1 - 2.9e-05 23.6 0.2 0.00089 18.7 0.0 2.9 4 0 0 4 4 4 1 Isopentenyl transferase AAA_33 PF13671.6 CCH60622.1 - 0.0039 17.3 0.0 0.012 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCH60622.1 - 0.0075 16.8 1.6 0.015 15.9 0.1 2.5 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCH60622.1 - 0.056 13.3 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 CCH60622.1 - 0.12 12.6 0.3 0.91 9.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CCH60622.1 - 0.13 11.5 0.7 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 CCH60622.1 - 1.8 9.1 4.5 3.7 8.1 3.8 2.2 1 1 0 1 1 1 0 ABC transporter Abhydrolase_1 PF00561.20 CCH60623.1 - 4.6e-16 59.2 0.1 3.3e-15 56.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH60623.1 - 7.7e-06 25.3 0.0 2.4e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 CCH60623.1 - 0.0046 16.3 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.22 CCH60623.1 - 0.0076 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 CCH60623.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF726 PF05277.12 CCH60623.1 - 0.24 10.3 0.0 0.47 9.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) MFS_1 PF07690.16 CCH60624.1 - 1.7e-22 79.8 43.0 5.9e-22 78.1 38.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Mtc PF03820.17 CCH60625.1 - 9.2e-121 402.7 0.1 1e-120 402.5 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier GHMP_kinases_N PF00288.26 CCH60626.1 - 1e-19 70.5 0.1 2.2e-19 69.4 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCH60626.1 - 8.5e-11 42.1 0.0 2.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CCH60626.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature WD40 PF00400.32 CCH60627.1 - 2.5e-17 62.9 21.8 1.6e-05 25.5 1.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Pkinase PF00069.25 CCH60628.1 - 2.6e-50 171.2 0.3 6.6e-50 169.9 0.3 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60628.1 - 1.7e-21 76.7 0.0 5.3e-21 75.1 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH60628.1 - 0.003 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCH60628.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP_bind_1 PF03029.17 CCH60629.1 - 2.7e-76 256.6 2.9 5.9e-76 255.4 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 CCH60629.1 - 0.048 14.1 0.1 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 CCH60629.1 - 0.38 11.3 3.0 2.6 8.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain UbiA PF01040.18 CCH60630.1 - 8.8e-47 159.5 16.1 1.3e-46 158.9 16.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Fucokinase PF07959.12 CCH60631.1 - 2.1e-05 23.7 0.5 5.5e-05 22.3 0.5 1.7 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 CCH60631.1 - 0.00058 19.5 5.1 0.0054 16.4 2.0 3.2 1 1 1 2 2 2 1 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCH60631.1 - 0.00079 19.8 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 CCH60631.1 - 0.0057 16.3 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase DUF3666 PF12408.8 CCH60631.1 - 0.014 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase TFIIA PF03153.13 CCH60631.1 - 1.9 8.4 12.4 6 6.8 7.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.13 CCH60631.1 - 2.9 7.7 10.9 13 5.6 8.1 2.7 2 0 0 2 2 2 0 Sigma-70, non-essential region AAA PF00004.29 CCH60632.1 - 1.2e-42 145.5 0.0 2.1e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH60632.1 - 1.6e-08 34.2 0.0 3.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCH60632.1 - 1.1e-07 31.7 0.3 2.6e-07 30.5 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CCH60632.1 - 1.8e-07 31.7 0.0 8.7e-05 23.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CCH60632.1 - 2.2e-06 27.7 0.2 7.5e-05 22.8 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCH60632.1 - 1.5e-05 25.2 0.0 3.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCH60632.1 - 3.9e-05 23.4 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CCH60632.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CCH60632.1 - 0.0018 18.7 0.0 0.0042 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CCH60632.1 - 0.0028 16.9 0.1 0.0053 16.0 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CCH60632.1 - 0.0031 17.8 1.5 0.032 14.5 0.1 2.5 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CCH60632.1 - 0.0067 15.8 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCH60632.1 - 0.0083 16.7 0.0 0.03 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCH60632.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 CCH60632.1 - 0.011 15.3 0.2 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_24 PF13479.6 CCH60632.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCH60632.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Fib_alpha PF08702.10 CCH60632.1 - 0.017 15.3 1.3 0.04 14.1 1.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_28 PF13521.6 CCH60632.1 - 0.029 14.6 0.0 0.069 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CCH60632.1 - 0.032 14.3 0.0 0.088 12.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 CCH60632.1 - 0.053 12.9 1.7 0.11 11.8 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 CCH60632.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CCH60632.1 - 0.067 12.6 0.2 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CCH60632.1 - 0.079 12.5 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CCH60632.1 - 0.092 11.8 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CCH60632.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCH60632.1 - 0.15 11.8 0.1 0.64 9.7 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain Hanta_nucleocap PF00846.18 CCH60632.1 - 0.16 10.4 0.4 0.24 9.8 0.4 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein AAA_11 PF13086.6 CCH60632.1 - 0.22 11.3 4.4 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PEPcase PF00311.17 CCH60632.1 - 0.24 9.4 0.8 0.33 9.0 0.8 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase PIGA PF08288.12 CCH60633.1 - 1.7e-45 153.5 2.5 6.2e-45 151.7 2.5 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CCH60633.1 - 1.5e-31 109.7 1.1 3.5e-31 108.5 0.3 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CCH60633.1 - 3.9e-28 98.1 0.0 8.6e-28 97.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCH60633.1 - 1.9e-22 80.1 0.0 4.7e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CCH60633.1 - 1.5e-12 48.3 0.0 2.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CCH60633.1 - 0.0011 19.0 0.8 0.0024 17.9 0.6 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CCH60633.1 - 0.041 14.3 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 TFR_dimer PF04253.15 CCH60634.1 - 1.5e-30 105.7 0.1 1.5e-30 105.7 0.1 2.6 3 0 0 3 3 3 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCH60634.1 - 0.0074 16.0 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 Methyltransf_15 PF09445.10 CCH60635.1 - 1.7e-58 196.9 0.6 1.7e-58 196.9 0.6 1.8 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CCH60635.1 - 0.00016 21.5 0.1 0.00033 20.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CCH60635.1 - 0.00027 20.6 0.5 0.0028 17.3 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 CCH60635.1 - 0.00077 18.8 1.6 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 CCH60635.1 - 0.0015 19.2 0.0 0.0035 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CCH60635.1 - 0.039 13.6 0.1 0.15 11.7 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 LepA_C PF06421.12 CCH60635.1 - 3.8 7.7 8.7 3.9 7.7 7.0 1.8 1 1 0 1 1 1 0 GTP-binding protein LepA C-terminus STIMATE PF12400.8 CCH60636.1 - 2.1e-44 151.1 9.1 2.1e-44 151.1 9.1 1.9 2 0 0 2 2 2 1 STIMATE family HAUS4 PF14735.6 CCH60637.1 - 0.039 13.6 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 LOH1CR12 PF10158.9 CCH60637.1 - 0.053 13.6 1.2 0.11 12.5 1.2 1.4 1 0 0 1 1 1 0 Tumour suppressor protein HATPase_c_3 PF13589.6 CCH60638.1 - 2.7e-08 33.7 0.0 6.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 CCH60638.1 - 2.4e-05 24.0 0.3 6.5e-05 22.6 0.3 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 CCH60638.1 - 3.3e-05 24.4 0.1 7.4e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CCH60638.1 - 0.075 12.8 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 MutL C terminal dimerisation domain ANAPC5 PF12862.7 CCH60639.1 - 3.1e-19 68.8 5.9 3.1e-19 68.8 5.9 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 DUF1125 PF06563.11 CCH60639.1 - 0.015 15.2 0.1 0.048 13.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) CLP1_P PF16575.5 CCH60640.1 - 2.7e-28 99.0 0.0 4.1e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CCH60640.1 - 2.5e-24 85.3 0.0 5.5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CCH60640.1 - 1.5e-13 51.2 0.0 2.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_33 PF13671.6 CCH60640.1 - 0.0024 18.0 0.0 0.0091 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CCH60640.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CCH60640.1 - 0.039 13.2 0.1 0.39 10.0 0.0 2.4 3 0 0 3 3 3 0 Septin AAA_16 PF13191.6 CCH60640.1 - 0.055 13.8 0.0 0.093 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CCH60640.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rhodanese PF00581.20 CCH60641.1 - 7.6e-16 58.6 0.0 1.5e-06 28.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Atg29_N PF18388.1 CCH60642.1 - 1.4e-19 69.6 0.6 3.3e-19 68.5 0.6 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain Med7 PF05983.11 CCH60642.1 - 0.12 12.4 5.1 0.2 11.7 5.1 1.5 1 1 0 1 1 1 0 MED7 protein DNA_pol_B PF00136.21 CCH60643.1 - 9.3e-97 324.6 0.0 1.4e-96 324.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCH60643.1 - 3.5e-24 85.6 10.0 1.1e-12 47.7 0.5 2.9 2 1 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCH60643.1 - 1e-09 38.7 9.6 2.5e-09 37.5 9.6 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RT_RNaseH_2 PF17919.1 CCH60644.1 - 3.3e-22 78.4 0.0 7e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH60644.1 - 1.3e-19 70.5 0.0 2.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCH60644.1 - 1.2e-17 63.7 1.2 4.2e-17 62.0 0.4 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain rve PF00665.26 CCH60644.1 - 3.1e-10 40.3 0.0 1.4e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain HIG_1_N PF04588.13 CCH60645.1 - 8.4e-17 61.1 3.1 1.3e-16 60.5 3.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Serglycin PF04360.12 CCH60645.1 - 0.042 13.8 3.3 0.061 13.3 3.3 1.3 1 0 0 1 1 1 0 Serglycin Homeodomain PF00046.29 CCH60646.1 - 6.8e-15 54.6 9.1 1.4e-14 53.7 9.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCH60646.1 - 0.00043 20.1 3.3 0.0005 19.9 1.4 2.0 2 0 0 2 2 2 1 Homeobox KN domain VESA1_N PF12785.7 CCH60646.1 - 0.27 10.1 11.5 0.35 9.8 11.5 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Ribosomal_S13 PF00416.22 CCH60647.1 - 4.8e-56 188.6 3.2 5.5e-56 188.5 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCH60647.1 - 0.0024 16.7 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CCH60647.1 - 0.12 12.6 0.1 0.9 9.8 0.1 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix motif Ribosomal_S17e PF00833.18 CCH60648.1 - 1.3e-56 189.7 0.7 1.6e-56 189.4 0.7 1.2 1 0 0 1 1 1 1 Ribosomal S17 PemK_toxin PF02452.17 CCH60648.1 - 0.063 13.7 0.2 0.12 12.8 0.2 1.4 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system ECM11 PF15463.6 CCH60649.1 - 3.6e-10 40.5 8.9 3.6e-10 40.5 8.9 2.8 2 1 0 2 2 2 1 Extracellular mutant protein 11 Nse5 PF08691.10 CCH60650.1 - 1.2e-87 294.8 35.4 1.7e-87 294.3 35.4 1.2 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 NAD4L PF06235.11 CCH60650.1 - 0.052 13.6 3.6 0.17 11.9 3.6 1.9 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) DOT1 PF08123.13 CCH60651.1 - 2.8e-89 298.1 1.4 7.8e-89 296.6 1.4 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 CCH60651.1 - 0.091 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase HMw1_D2 PF18254.1 CCH60651.1 - 0.093 13.1 0.0 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 HMW1 domain 2 UDG PF03167.19 CCH60652.1 - 2e-20 73.4 0.1 2.9e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LRS4 PF10422.9 CCH60653.1 - 1.2e-05 25.0 37.0 0.0014 18.3 37.0 3.0 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 YabA PF06156.13 CCH60653.1 - 0.002 18.7 5.2 0.002 18.7 5.2 3.7 1 1 2 3 3 3 1 Initiation control protein YabA DUF641 PF04859.12 CCH60653.1 - 0.0073 16.6 5.1 0.0073 16.6 5.1 3.3 3 1 1 4 4 4 1 Plant protein of unknown function (DUF641) TPR_MLP1_2 PF07926.12 CCH60653.1 - 0.015 15.4 4.9 0.015 15.4 4.9 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 CCH60653.1 - 0.064 13.9 14.7 0.07 13.8 1.1 3.7 2 1 1 3 3 3 0 SlyX Fzo_mitofusin PF04799.13 CCH60653.1 - 0.43 10.1 13.2 0.53 9.8 4.5 2.4 2 0 0 2 2 2 0 fzo-like conserved region DUF3007 PF11460.8 CCH60653.1 - 0.74 10.1 2.3 35 4.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) GvpK PF05121.12 CCH60653.1 - 0.81 9.8 6.4 17 5.5 2.0 2.7 2 0 0 2 2 2 0 Gas vesicle protein K DUF1664 PF07889.12 CCH60653.1 - 2.5 8.2 9.7 3.7 7.6 2.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CCH60653.1 - 3.2 7.0 23.2 2.4e+02 0.9 23.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 CCH60653.1 - 6.6 7.3 24.9 5.1 7.6 11.2 2.5 2 0 0 2 2 2 0 Apg6 coiled-coil region KfrA_N PF11740.8 CCH60653.1 - 7.5 7.3 10.4 4.6 7.9 4.5 2.5 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term TSC22 PF01166.18 CCH60653.1 - 8.7 6.7 15.1 6.4 7.2 0.3 4.6 2 2 1 4 4 4 0 TSC-22/dip/bun family OST3_OST6 PF04756.13 CCH60654.1 - 2.2e-48 165.1 12.4 4.8e-25 88.5 9.6 2.0 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CCH60654.1 - 0.18 11.8 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain EamA PF00892.20 CCH60655.1 - 1.9e-11 44.3 39.7 4e-06 27.0 4.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 CCH60655.1 - 0.0003 20.3 15.1 0.00053 19.4 4.3 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF3955 PF13127.6 CCH60655.1 - 0.0011 18.7 0.4 0.0011 18.7 0.4 3.8 4 1 1 5 5 5 1 Protein of unknown function (DUF3955) Herpes_pp38 PF04846.13 CCH60655.1 - 0.18 11.7 0.3 0.18 11.7 0.3 2.6 2 0 0 2 2 2 0 Herpesvirus pp38 phosphoprotein Peptidase_A2B PF12384.8 CCH60656.1 - 2.1e-10 40.4 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase RVT_1 PF00078.27 CCH60656.1 - 8.8e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 CCH60656.1 - 0.0002 21.9 0.0 0.0005 20.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCH60656.1 - 0.0024 18.4 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CCH60656.1 - 0.006 16.4 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 CCH60657.1 - 1.7e-14 53.7 0.5 3.4e-14 52.7 0.5 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CCH60657.1 - 8.7e-07 29.1 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Metallophos PF00149.28 CCH60659.1 - 1.9e-35 123.2 0.2 3e-35 122.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCH60659.1 - 5.4e-18 65.2 0.1 9.9e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain LCM PF04072.14 CCH60660.1 - 9.2e-24 84.4 0.0 1.2e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TAFII28 PF04719.14 CCH60661.1 - 1e-25 89.6 0.9 9.1e-23 80.2 0.3 2.9 3 0 0 3 3 3 2 hTAFII28-like protein conserved region PIG-S PF10510.9 CCH60662.1 - 2.7e-117 392.8 9.7 3.8e-117 392.3 9.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein RRM_1 PF00076.22 CCH60663.1 - 4.4e-27 93.7 0.3 4.3e-17 61.7 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCH60663.1 - 0.0028 17.3 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH60663.1 - 0.2 11.8 0.1 0.92 9.7 0.1 2.1 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 CCH60663.1 - 0.24 11.3 0.0 0.52 10.2 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Rad33 PF08730.10 CCH60664.1 - 5.7e-12 45.9 5.9 1.8e-08 34.6 0.4 2.1 1 1 1 2 2 2 2 Rad33 Spt5_N PF11942.8 CCH60665.1 - 2.5e-21 76.5 10.1 2.5e-21 76.5 10.1 4.3 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 CCH60665.1 - 3.3e-21 75.0 0.0 8.1e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CCH60665.1 - 4.4e-14 51.9 13.2 0.0017 18.3 0.9 4.8 4 0 0 4 4 4 4 KOW motif DUF3912 PF13051.6 CCH60665.1 - 0.001 19.3 1.2 0.44 10.8 0.1 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) CTD PF12815.7 CCH60665.1 - 0.011 16.2 25.3 0.011 16.2 25.3 4.0 2 2 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF2118 PF09891.9 CCH60665.1 - 0.029 14.3 0.6 0.073 13.0 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Myosin_N PF02736.19 CCH60665.1 - 0.031 14.1 0.3 0.14 12.0 0.3 2.3 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain mCpol PF18182.1 CCH60665.1 - 0.37 11.2 4.3 1.9 8.8 0.0 3.2 4 0 0 4 4 4 0 minimal CRISPR polymerase domain Ribosomal_L33 PF00471.20 CCH60666.1 - 0.024 15.1 0.0 0.051 14.0 0.0 1.8 1 1 0 1 1 1 0 Ribosomal protein L33 DPM2 PF07297.12 CCH60667.1 - 6.6e-10 39.2 8.0 6.8e-10 39.1 8.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CCH60667.1 - 0.17 11.8 7.7 0.21 11.5 7.7 1.1 1 0 0 1 1 1 0 PIG-P Rpn9_C PF18261.1 CCH60668.1 - 5e-18 64.4 2.5 1.1e-17 63.3 2.5 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix PCI PF01399.27 CCH60668.1 - 1.9e-12 47.6 0.4 5.3e-12 46.2 0.4 1.8 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CCH60668.1 - 0.05 13.6 0.8 0.12 12.3 0.2 2.0 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family PX PF00787.24 CCH60669.1 - 4.7e-17 62.0 0.0 1.8e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 PX domain SesA PF17107.5 CCH60669.1 - 1.4 9.1 5.1 2 8.6 1.5 2.8 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Dynein_light PF01221.18 CCH60670.1 - 6.1e-33 113.0 0.3 6.7e-33 112.9 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CCH60670.1 - 0.034 14.8 0.0 0.044 14.5 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Sterol_MT_C PF08498.10 CCH60671.1 - 1.9e-24 85.8 1.3 3.2e-24 85.0 1.3 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CCH60671.1 - 1.7e-19 70.3 0.0 3.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH60671.1 - 1.5e-17 64.1 0.0 3.3e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH60671.1 - 1.7e-16 60.3 0.0 2.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH60671.1 - 1.8e-13 50.7 0.0 2.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH60671.1 - 4.6e-13 49.1 0.6 6.1e-13 48.7 0.6 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CCH60671.1 - 1.2e-12 48.4 0.1 3.9e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH60671.1 - 8.9e-10 38.3 0.0 1.9e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CCH60671.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 CCH60671.1 - 0.0028 17.1 0.1 0.0074 15.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CCH60671.1 - 0.0037 16.9 0.6 0.015 14.9 0.4 1.8 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CCH60671.1 - 0.019 14.5 0.0 0.054 13.0 0.0 1.8 1 0 0 1 1 1 0 Putative methyltransferase SBP_bac_5 PF00496.22 CCH60671.1 - 0.043 12.8 0.5 0.065 12.2 0.5 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Methyltransf_32 PF13679.6 CCH60671.1 - 0.079 13.0 0.2 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 CCH60671.1 - 0.084 12.4 0.1 0.23 11.0 0.1 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 CCH60671.1 - 0.12 11.4 0.0 0.3 10.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 CCH60671.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PAP1 PF08601.10 CCH60672.1 - 1.2e-20 74.6 4.8 1.2e-20 74.6 4.8 4.8 1 1 4 5 5 5 1 Transcription factor PAP1 bZIP_1 PF00170.21 CCH60672.1 - 3.6e-06 27.0 9.0 3.6e-06 27.0 9.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CCH60672.1 - 0.0043 17.1 9.4 0.0043 17.1 9.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CCH60672.1 - 0.13 12.8 13.0 0.53 10.8 10.6 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor AAA_lid_3 PF17862.1 CCH60672.1 - 0.23 11.3 0.6 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA+ lid domain AMPKBI PF04739.15 CCH60673.1 - 4.6e-17 62.0 0.4 4.6e-17 62.0 0.4 3.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CCH60673.1 - 1.7e-08 34.5 0.0 6.5e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Zn_clus PF00172.18 CCH60675.1 - 1.2e-07 31.8 7.5 2.1e-07 30.9 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup_retrotrp_bd PF10599.9 CCH60675.1 - 0.36 11.5 4.5 0.22 12.2 1.2 2.4 2 0 0 2 2 2 0 Retro-transposon transporting motif IMS PF00817.20 CCH60676.1 - 1.3e-40 138.8 0.0 2.7e-40 137.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 CCH60676.1 - 1.7e-07 30.7 1.9 5.1e-07 29.2 1.9 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 CCH60676.1 - 0.00055 20.1 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Ribosomal_L11_N PF03946.14 CCH60677.1 - 2.8e-21 75.1 1.2 5.9e-21 74.1 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCH60677.1 - 1.8e-16 60.4 1.1 4.1e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Mak10 PF04112.13 CCH60678.1 - 1.8e-43 148.0 1.4 8.6e-43 145.7 0.6 2.4 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Myb_DNA-bind_4 PF13837.6 CCH60678.1 - 0.21 12.0 0.9 1.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TPR_14 PF13428.6 CCH60679.1 - 6.6e-07 29.6 0.2 0.84 10.6 0.0 6.1 6 1 1 7 7 7 2 Tetratricopeptide repeat NRDE-2 PF08424.10 CCH60679.1 - 0.069 12.3 17.5 0.45 9.6 2.6 5.0 5 1 1 6 6 6 0 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 CCH60679.1 - 0.079 13.2 6.2 0.32 11.3 0.0 5.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCH60679.1 - 0.15 12.2 2.0 3.8 7.9 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CCH60679.1 - 0.17 12.4 1.4 70 4.1 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat EXS PF03124.14 CCH60680.1 - 6.8e-53 180.1 28.6 7.8e-53 179.9 28.6 1.0 1 0 0 1 1 1 1 EXS family Nop25 PF09805.9 CCH60681.1 - 1.1e-35 123.0 17.7 1.1e-35 123.0 17.7 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Formyl_trans_N PF00551.19 CCH60682.1 - 1.4e-47 161.7 0.2 1.7e-47 161.5 0.2 1.0 1 0 0 1 1 1 1 Formyl transferase Proteasome PF00227.26 CCH60683.1 - 1.2e-46 158.6 0.0 1.6e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CCH60683.1 - 4.4e-11 42.0 0.2 4.4e-11 42.0 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal ISN1 PF06437.11 CCH60684.1 - 8.8e-175 581.5 0.0 1e-174 581.3 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase ADH_zinc_N PF00107.26 CCH60685.1 - 8.3e-10 38.7 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH60685.1 - 0.004 17.0 0.0 0.045 13.6 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCH60685.1 - 0.099 13.7 0.0 0.17 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ABC2_membrane PF01061.24 CCH60686.1 - 4.6e-82 274.5 50.0 2.4e-43 148.0 18.9 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCH60686.1 - 9.5e-41 139.5 0.1 7e-19 68.7 0.0 3.8 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 CCH60686.1 - 3.9e-30 103.6 16.0 7.4e-29 99.5 0.0 3.8 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CCH60686.1 - 2.1e-15 57.1 2.3 2.3e-15 57.0 0.2 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CCH60686.1 - 1.4e-07 32.1 0.0 5.2e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CCH60686.1 - 6.1e-07 29.2 0.1 2.4e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCH60686.1 - 1.5e-05 25.1 0.0 0.052 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CCH60686.1 - 2.2e-05 24.4 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CCH60686.1 - 7.4e-05 23.3 0.0 0.0051 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CCH60686.1 - 0.00021 20.8 0.0 0.0075 15.7 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH60686.1 - 0.00046 19.9 0.6 0.0086 15.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCH60686.1 - 0.0011 18.9 0.0 0.3 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 CCH60686.1 - 0.0013 18.3 1.5 0.49 9.9 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CCH60686.1 - 0.0025 18.3 0.6 0.046 14.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 CCH60686.1 - 0.0071 16.6 2.7 0.47 10.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CCH60686.1 - 0.0084 16.0 2.5 3.1 7.7 0.1 2.9 3 0 0 3 3 3 2 NACHT domain AAA_28 PF13521.6 CCH60686.1 - 0.025 14.8 1.9 0.27 11.5 0.2 2.9 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CCH60686.1 - 0.026 13.8 0.0 0.61 9.4 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 CCH60686.1 - 0.053 13.2 1.3 3.8 7.2 0.3 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CCH60686.1 - 0.058 13.5 1.2 19 5.4 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_17 PF13207.6 CCH60686.1 - 0.086 13.3 0.1 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CCH60686.1 - 0.2 11.7 0.3 1.7 8.7 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mito_fiss_reg PF05308.11 CCH60686.1 - 0.54 10.3 5.6 1.2 9.2 5.6 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator AAA_13 PF13166.6 CCH60686.1 - 0.79 8.3 4.4 4.6 5.8 0.0 3.5 5 0 0 5 5 5 0 AAA domain Ribosomal_L13 PF00572.18 CCH60687.1 - 2.7e-45 153.7 0.6 3.3e-45 153.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 S1 PF00575.23 CCH60688.1 - 4.3e-18 65.4 0.1 6.7e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CCH60688.1 - 1.6e-16 60.4 0.0 3.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CCH60688.1 - 4.4e-06 27.0 0.0 7.6e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 IU_nuc_hydro PF01156.19 CCH60689.1 - 3.5e-64 217.3 0.0 4e-64 217.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ABC2_membrane PF01061.24 CCH60690.1 - 6.7e-85 283.8 49.4 1.8e-45 154.9 20.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCH60690.1 - 3.6e-40 137.7 0.1 6.7e-19 68.8 0.0 3.5 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 CCH60690.1 - 4.1e-37 125.9 3.6 1.9e-32 111.0 0.2 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCH60690.1 - 1.5e-18 67.2 0.8 2.9e-18 66.3 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CCH60690.1 - 1.3e-07 32.2 0.0 6.3e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CCH60690.1 - 4.3e-07 29.7 0.1 1.8e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CCH60690.1 - 7.3e-06 25.3 31.3 0.0016 17.6 8.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 CCH60690.1 - 1.1e-05 25.7 0.1 0.049 13.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CCH60690.1 - 3.8e-05 23.7 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CCH60690.1 - 5.4e-05 23.7 0.0 0.0049 17.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CCH60690.1 - 0.00036 20.1 0.0 0.0072 15.8 0.0 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH60690.1 - 0.00036 20.2 0.6 0.0083 15.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCH60690.1 - 0.00085 19.2 0.0 0.3 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 CCH60690.1 - 0.0013 18.4 1.5 0.48 10.0 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CCH60690.1 - 0.0014 18.9 1.3 0.46 10.8 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 CCH60690.1 - 0.0024 18.4 0.5 0.045 14.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CCH60690.1 - 0.012 15.5 3.1 3 7.7 0.1 2.9 3 0 0 3 3 3 0 NACHT domain DnaB_C PF03796.15 CCH60690.1 - 0.021 14.2 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 CCH60690.1 - 0.04 14.2 2.2 0.26 11.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CCH60690.1 - 0.049 13.4 1.3 3.7 7.2 0.3 2.5 2 0 0 2 2 2 0 AAA domain OCD_Mu_crystall PF02423.15 CCH60690.1 - 0.067 12.1 0.1 0.35 9.7 0.0 2.1 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family AAA_17 PF13207.6 CCH60690.1 - 0.077 13.4 0.3 1.6 9.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain CBFD_NFYB_HMF PF00808.23 CCH60691.1 - 4.6e-13 49.3 0.4 7.4e-13 48.6 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2956 PF11169.8 CCH60691.1 - 0.013 15.7 0.6 0.021 15.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Histone PF00125.24 CCH60691.1 - 0.1 12.9 1.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Glyco_transf_22 PF03901.17 CCH60692.1 - 7.4e-72 242.9 41.0 9.6e-72 242.5 41.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2368 PF10166.9 CCH60692.1 - 0.07 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) AAA PF00004.29 CCH60693.1 - 5.2e-46 156.3 2.2 1.2e-45 155.2 0.0 2.5 3 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCH60693.1 - 5e-09 36.0 0.2 3.5e-08 33.3 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCH60693.1 - 1.8e-08 34.7 0.0 4.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCH60693.1 - 1.2e-07 32.3 0.7 9.4e-06 26.1 0.2 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CCH60693.1 - 1.4e-07 31.6 0.1 6.6e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCH60693.1 - 8.3e-05 22.9 4.1 0.0031 17.8 0.7 3.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CCH60693.1 - 9.4e-05 21.7 0.0 0.00017 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 CCH60693.1 - 0.00016 21.4 0.1 0.00038 20.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CCH60693.1 - 0.00025 20.9 0.0 0.00074 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CCH60693.1 - 0.00081 19.3 0.2 0.0028 17.6 0.0 2.0 3 0 0 3 3 2 1 NTPase AAA_18 PF13238.6 CCH60693.1 - 0.0011 19.5 0.0 0.0074 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCH60693.1 - 0.0017 18.3 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CCH60693.1 - 0.0019 18.6 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 CCH60693.1 - 0.0021 17.8 0.0 0.0093 15.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 CCH60693.1 - 0.0035 16.8 0.4 0.49 9.8 0.0 3.0 3 0 0 3 3 3 1 Bacterial TniB protein AAA_14 PF13173.6 CCH60693.1 - 0.0036 17.3 0.0 0.0096 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCH60693.1 - 0.0036 16.8 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCH60693.1 - 0.0038 17.0 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCH60693.1 - 0.004 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCH60693.1 - 0.0057 16.4 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 CCH60693.1 - 0.0062 16.7 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCH60693.1 - 0.0063 15.9 0.1 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CCH60693.1 - 0.0065 16.3 0.3 0.069 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CCH60693.1 - 0.012 14.8 0.0 0.028 13.6 0.0 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CCH60693.1 - 0.012 15.3 0.1 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 CCH60693.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCH60693.1 - 0.017 15.1 0.1 0.16 11.9 0.0 2.4 1 1 1 2 2 2 0 NACHT domain ATPase_2 PF01637.18 CCH60693.1 - 0.022 14.7 2.1 0.35 10.7 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CCH60693.1 - 0.07 12.7 0.5 0.41 10.2 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCH60693.1 - 0.13 12.6 0.1 0.41 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 CCH60693.1 - 1 9.8 9.2 14 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain She9_MDM33 PF05546.11 CCH60694.1 - 2.3e-80 269.1 11.9 2.3e-80 269.1 11.9 2.3 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.20 CCH60694.1 - 0.0088 15.7 0.5 0.021 14.6 0.5 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein DUF4226 PF10774.9 CCH60694.1 - 0.023 15.0 0.2 0.023 15.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF4796 PF16044.5 CCH60694.1 - 0.033 13.8 3.0 0.087 12.4 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) DUF4407 PF14362.6 CCH60694.1 - 3.8 6.8 7.9 7.2 5.9 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BST2 PF16716.5 CCH60694.1 - 4.2 8.0 24.3 3.6 8.2 4.2 3.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 G-patch_2 PF12656.7 CCH60695.1 - 5.4e-19 68.0 0.2 5.4e-19 68.0 0.2 2.1 2 0 0 2 2 2 1 G-patch domain KH_8 PF17903.1 CCH60696.1 - 1.8e-05 24.7 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCH60696.1 - 0.34 10.8 3.2 0.16 11.8 0.4 1.9 2 0 0 2 2 2 0 KH domain AAA PF00004.29 CCH60697.1 - 0.0022 18.4 0.0 0.0057 17.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIID-18kDa PF02269.16 CCH60698.1 - 7.8e-33 112.4 0.2 3.8e-32 110.2 0.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF1931 PF09123.11 CCH60698.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) TPK_catalytic PF04263.16 CCH60699.1 - 1.4e-28 99.4 0.1 1.7e-27 95.9 0.1 2.0 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CCH60699.1 - 2.6e-09 36.7 0.1 5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Sec7 PF01369.20 CCH60700.1 - 4.8e-65 218.7 2.8 4.8e-65 218.7 2.8 2.4 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CCH60700.1 - 4.5e-10 39.7 2.8 4.5e-10 39.7 2.8 2.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CCH60700.1 - 0.001 18.8 4.6 0.001 18.8 4.6 3.5 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Rav1p_C PF12234.8 CCH60701.1 - 1.3e-218 727.5 9.5 1.5e-217 724.1 6.3 2.2 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 CCH60701.1 - 0.016 16.1 1.5 7.8 7.6 0.0 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat Orthopox_F14 PF06076.12 CCH60701.1 - 0.17 12.2 0.6 0.5 10.7 0.0 2.1 2 0 0 2 2 2 0 Orthopoxvirus F14 protein SNF2_N PF00176.23 CCH60703.1 - 9.3e-73 244.9 0.1 1.8e-72 244.0 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH60703.1 - 2.8e-18 66.3 0.4 2.6e-17 63.2 0.1 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH60703.1 - 1.3e-07 31.8 0.1 1.3e-07 31.8 0.1 3.9 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CCH60703.1 - 0.13 12.0 0.1 0.13 12.0 0.1 5.4 4 2 1 6 6 6 0 AAA domain Rieske PF00355.26 CCH60704.1 - 2.3e-11 43.4 0.0 3.8e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CCH60704.1 - 7.8e-10 39.1 0.3 1.8e-09 37.9 0.3 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Ribosomal_L7Ae PF01248.26 CCH60706.1 - 1.2e-26 92.2 0.1 1.5e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CCH60706.1 - 0.0043 16.9 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CCH60706.1 - 0.014 15.5 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 MULE PF10551.9 CCH60707.1 - 0.0068 16.8 0.1 0.039 14.4 0.1 2.4 2 0 0 2 2 2 1 MULE transposase domain FA_hydroxylase PF04116.13 CCH60708.1 - 7.6e-27 94.3 19.3 7.6e-27 94.3 19.3 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Metallophos PF00149.28 CCH60709.1 - 1.5e-15 58.3 0.1 1.5e-15 58.3 0.1 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Folliculin PF11704.8 CCH60710.1 - 4.3e-39 134.3 1.4 8.7e-39 133.3 1.4 1.5 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport BAH PF01426.18 CCH60711.1 - 2.9e-22 78.8 0.9 7.7e-22 77.4 0.1 2.2 2 0 0 2 2 2 1 BAH domain Bromodomain PF00439.25 CCH60711.1 - 2.4e-16 59.6 9.0 6.7e-11 42.1 0.6 3.3 3 0 0 3 3 3 2 Bromodomain DUF643 PF04867.12 CCH60711.1 - 0.083 13.5 1.5 2.7 8.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Flavodoxin_2 PF02525.17 CCH60712.1 - 1.3e-35 122.9 0.1 1.5e-35 122.8 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCH60712.1 - 5e-09 36.1 0.0 9.7e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase ApbA_C PF08546.11 CCH60712.1 - 0.031 14.5 0.0 0.066 13.4 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal AA_permease_2 PF13520.6 CCH60713.1 - 5.3e-85 285.8 48.7 6.8e-85 285.4 48.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCH60713.1 - 8.5e-19 67.5 45.0 1.1e-18 67.1 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 CCH60714.1 - 3.2e-45 154.6 0.9 3.7e-45 154.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60714.1 - 2.8e-26 92.3 0.0 5.2e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH60714.1 - 3.2e-06 26.7 0.0 6.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PDGLE PF13190.6 CCH60714.1 - 0.028 14.3 0.8 0.061 13.2 0.8 1.6 1 0 0 1 1 1 0 PDGLE domain Macoilin PF09726.9 CCH60714.1 - 0.71 8.4 10.3 1.1 7.8 10.3 1.2 1 0 0 1 1 1 0 Macoilin family Androgen_recep PF02166.16 CCH60714.1 - 1.5 7.6 5.1 2.4 6.9 5.1 1.3 1 0 0 1 1 1 0 Androgen receptor DUF2439 PF10382.9 CCH60715.1 - 8.7e-21 74.0 2.7 8.7e-21 74.0 2.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) Trypan_PARP PF05887.11 CCH60715.1 - 0.2 11.6 8.7 0.35 10.9 8.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3751 PF12571.8 CCH60716.1 - 0.13 12.4 3.2 0.3 11.1 3.2 1.6 1 0 0 1 1 1 0 Phage tail-collar fibre protein Kelch_4 PF13418.6 CCH60718.1 - 5.7e-13 48.6 0.2 1.6e-07 31.2 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CCH60718.1 - 7.9e-10 38.7 0.7 1.2e-05 25.4 0.0 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CCH60718.1 - 3e-08 33.8 0.2 0.00039 20.6 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CCH60718.1 - 1.1e-06 28.1 0.1 0.023 14.3 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CCH60718.1 - 0.0023 17.9 0.0 0.36 10.9 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CCH60718.1 - 0.004 17.1 0.0 0.36 10.9 0.0 3.1 2 0 0 2 2 2 1 Kelch motif CNDH2_N PF06278.11 CCH60718.1 - 0.065 13.4 6.0 0.88 9.8 0.4 3.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Hist_deacetyl PF00850.19 CCH60719.1 - 9e-82 275.0 0.0 1.2e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain COX6A PF02046.15 CCH60720.1 - 5.2e-34 117.1 0.5 5.9e-34 116.9 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.32 CCH60721.1 - 1.1e-16 60.9 0.5 0.0034 18.2 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Presenilin PF01080.17 CCH60721.1 - 5.7 5.6 7.6 8.7 5.0 7.6 1.2 1 0 0 1 1 1 0 Presenilin Ribosomal_S26e PF01283.19 CCH60722.1 - 6.2e-51 171.4 10.5 7.2e-51 171.1 10.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e COX5B PF01215.19 CCH60723.1 - 7.2e-62 206.8 0.2 9.1e-62 206.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Transp_cyt_pur PF02133.15 CCH60724.1 - 1.3e-11 44.0 36.3 1.3e-11 44.0 36.3 2.1 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sterol-sensing PF12349.8 CCH60724.1 - 0.0012 18.7 1.4 0.0046 16.8 1.4 2.0 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Mnd1 PF03962.15 CCH60725.1 - 2.1e-25 88.8 0.4 2.1e-25 88.8 0.4 3.3 4 0 0 4 4 4 1 Mnd1 HTH domain LZ3wCH PF18517.1 CCH60725.1 - 0.0012 18.9 0.7 0.0012 18.9 0.7 3.4 3 2 1 4 4 4 1 Leucine zipper with capping helix domain Seryl_tRNA_N PF02403.22 CCH60725.1 - 9.4 6.5 13.3 0.27 11.5 4.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArfGap PF01412.18 CCH60726.1 - 6.3e-31 106.9 0.2 6.3e-31 106.9 0.2 3.0 2 1 0 3 3 3 1 Putative GTPase activating protein for Arf Kri1_C PF12936.7 CCH60726.1 - 0.039 14.1 0.1 0.16 12.1 0.1 2.1 1 0 0 1 1 1 0 KRI1-like family C-terminal Ogr_Delta PF04606.12 CCH60726.1 - 0.074 13.0 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger HydF_dimer PF18128.1 CCH60726.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain DUF3543 PF12063.8 CCH60727.1 - 8.4e-72 241.6 2.4 8.4e-72 241.6 2.4 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CCH60727.1 - 8.7e-59 199.0 0.2 2.6e-58 197.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60727.1 - 1.8e-44 152.0 0.0 3.2e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CCH60728.1 - 1.5e-55 188.4 3.4 5.2e-49 167.0 0.2 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60728.1 - 1.3e-25 90.2 2.1 8.2e-23 81.0 0.2 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCH60728.1 - 1.8e-05 24.2 0.0 4.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Phage_pRha PF09669.10 CCH60728.1 - 0.1 13.2 1.7 6.7 7.3 0.0 3.7 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Vfa1 PF08432.10 CCH60729.1 - 1.4e-40 139.6 3.2 1.8e-40 139.2 3.2 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Prp19 PF08606.11 CCH60729.1 - 0.12 12.4 0.6 0.12 12.4 0.6 2.4 2 1 1 3 3 3 0 Prp19/Pso4-like DUF4407 PF14362.6 CCH60729.1 - 1.8 7.9 5.6 2.4 7.5 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 CCH60729.1 - 3.9 8.0 10.0 1.2 9.6 6.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Sas10_Utp3 PF04000.15 CCH60730.1 - 1.9e-12 47.6 3.7 1.9e-12 47.6 3.7 2.5 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CDV3 PF15359.6 CCH60730.1 - 0.024 15.1 4.3 0.024 15.1 4.3 2.3 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 DNA_repr_REX1B PF14966.6 CCH60730.1 - 0.35 11.6 7.1 0.17 12.6 2.6 2.5 3 0 0 3 3 3 0 DNA repair REX1-B Ribosomal_S8e PF01201.22 CCH60731.1 - 4.4e-46 156.4 0.1 7.1e-46 155.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.8 CCH60731.1 - 0.12 12.3 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) PUF PF00806.19 CCH60732.1 - 5.4e-48 158.1 32.2 2e-08 33.5 1.3 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fungal_trans PF04082.18 CCH60734.1 - 1e-62 211.6 10.2 1e-62 211.6 10.2 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CCH60734.1 - 5.8e-09 35.9 8.9 0.00069 19.9 3.6 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH60734.1 - 0.00022 21.8 12.4 0.018 15.8 2.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CCH60734.1 - 0.024 14.9 1.2 0.14 12.5 0.8 2.4 1 1 1 2 2 2 0 C2H2-type zinc ribbon DUF3764 PF12594.8 CCH60734.1 - 0.085 12.9 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) Lectin_leg-like PF03388.13 CCH60735.1 - 1.6e-40 138.9 0.0 2.7e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family ABC2_membrane_3 PF12698.7 CCH60735.1 - 0.032 13.4 6.9 0.02 14.0 5.5 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Striatin PF08232.12 CCH60735.1 - 0.06 13.9 2.2 0.1 13.2 2.2 1.3 1 0 0 1 1 1 0 Striatin family Tnp_22_dsRBD PF17490.2 CCH60735.1 - 0.062 13.3 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain DEP PF00610.21 CCH60736.1 - 5.9e-11 42.3 0.0 1.7e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 CCH60736.1 - 1.5e-08 34.6 8.8 7.7e-06 25.8 0.2 3.6 3 0 0 3 3 3 2 RhoGAP domain FCH PF00611.23 CCH60736.1 - 2.6e-07 30.8 0.7 1.1e-06 28.9 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1869 PF08956.10 CCH60736.1 - 0.033 14.1 0.3 0.48 10.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) PMM PF03332.13 CCH60738.1 - 3.7e-114 380.0 0.7 4.2e-114 379.8 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CCH60738.1 - 7.3e-05 22.6 0.0 0.0009 19.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCH60738.1 - 0.088 13.1 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-C2H2_jaz PF12171.8 CCH60739.1 - 1.9e-09 37.5 6.9 3.1e-09 36.9 4.8 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CCH60739.1 - 0.00053 20.3 0.1 0.00091 19.5 0.1 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-AD PF07776.15 CCH60739.1 - 0.055 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-U1 PF06220.12 CCH60739.1 - 0.085 12.6 1.5 0.14 11.9 1.5 1.3 1 0 0 1 1 1 0 U1 zinc finger DUF4752 PF15944.5 CCH60739.1 - 0.11 12.6 0.1 3.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4752) DUF3088 PF11287.8 CCH60739.1 - 0.13 12.1 0.1 0.53 10.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3088) zf-C2HE PF16278.5 CCH60739.1 - 1.4 9.4 4.2 1.3 9.6 1.7 2.2 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger VASt PF16016.5 CCH60740.1 - 6.9e-29 101.2 1.2 1.4e-28 100.3 1.2 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain SPX PF03105.19 CCH60740.1 - 0.97 9.3 15.1 0.063 13.2 10.2 1.5 2 0 0 2 2 2 0 SPX domain Macoilin PF09726.9 CCH60740.1 - 1.1 7.7 11.6 0.07 11.7 6.8 1.5 2 0 0 2 2 2 0 Macoilin family Apt1 PF10351.9 CCH60740.1 - 5.3 5.8 14.8 0.19 10.5 8.3 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cu-oxidase_3 PF07732.15 CCH60741.1 - 4.1e-45 152.6 1.4 8.2e-42 142.0 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CCH60741.1 - 3e-41 140.4 9.7 3.1e-38 130.6 0.2 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CCH60741.1 - 3.9e-15 56.3 1.9 6.4e-13 49.1 0.0 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.6 CCH60741.1 - 0.00014 21.9 0.0 2 8.6 0.0 3.7 4 0 0 4 4 4 2 Cupredoxin-like domain AATase PF07247.12 CCH60743.1 - 4.8e-44 150.7 8.1 1.2e-43 149.4 8.1 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase GTP_EFTU PF00009.27 CCH60744.1 - 1.1e-61 207.8 0.4 1.9e-61 207.0 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCH60744.1 - 3.9e-33 113.8 0.2 1.4e-32 112.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CCH60744.1 - 1.2e-28 99.0 0.0 2.5e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCH60744.1 - 3.8e-21 74.9 0.0 9.2e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCH60744.1 - 1.1e-13 51.4 0.5 3e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CCH60744.1 - 1.6e-06 27.9 0.0 4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CCH60744.1 - 0.005 16.9 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 CCH60744.1 - 0.0069 16.8 0.0 0.079 13.4 0.0 2.5 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain SPC22 PF04573.12 CCH60745.1 - 2.9e-56 189.6 2.0 3.4e-56 189.4 2.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit TMEM208_SND2 PF05620.11 CCH60746.1 - 5.1e-47 159.8 0.1 5.7e-47 159.6 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Tetraspanin PF00335.20 CCH60746.1 - 0.05 13.3 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family Methyltransf_34 PF11312.8 CCH60747.1 - 1e-84 284.4 0.0 1.4e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase ABC_tran_Xtn PF12848.7 CCH60748.1 - 0.014 15.5 0.7 0.014 15.5 0.7 2.6 1 1 1 2 2 2 0 ABC transporter DUF148 PF02520.17 CCH60748.1 - 0.16 12.1 17.5 0.52 10.4 4.2 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Ribosomal_L22e PF01776.17 CCH60749.1 - 6.5e-40 135.9 0.5 8.1e-40 135.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.12 CCH60750.1 - 1.5e-138 461.5 2.7 2.2e-138 460.9 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) bZIP_1 PF00170.21 CCH60751.1 - 8.2e-08 32.2 9.5 8.2e-08 32.2 9.5 2.2 2 0 0 2 2 2 1 bZIP transcription factor SHMT PF00464.19 CCH60752.1 - 1.5e-191 636.3 0.0 1.7e-191 636.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 CCH60752.1 - 3.8e-05 23.0 0.0 9.4e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Glyco_hydro_47 PF01532.20 CCH60753.1 - 5.2e-80 269.6 1.0 7.1e-80 269.1 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 CCH60753.1 - 0.029 12.9 0.0 4.1 5.8 0.0 2.9 3 1 0 3 3 3 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 CCH60753.1 - 0.14 11.7 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Pkinase PF00069.25 CCH60754.1 - 5.7e-25 88.2 0.4 8e-25 87.7 0.4 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60754.1 - 8.7e-15 54.7 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH60754.1 - 0.00081 18.3 0.2 0.00096 18.0 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CCH60754.1 - 0.0054 16.3 0.2 0.019 14.5 0.1 1.8 1 1 1 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.23 CCH60754.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CCH60754.1 - 0.049 13.0 0.1 0.14 11.5 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCH60754.1 - 0.063 12.9 0.4 0.13 11.9 0.4 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 FA_hydroxylase PF04116.13 CCH60755.1 - 1.8e-21 76.9 19.8 1.8e-21 76.9 19.8 2.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ABC_tran PF00005.27 CCH60756.1 - 9.8e-17 61.8 0.1 3e-16 60.2 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCH60756.1 - 2.8e-09 37.2 0.6 0.0011 18.9 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH60756.1 - 0.00051 19.5 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH60756.1 - 0.0019 17.9 0.1 0.0039 16.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCH60756.1 - 0.0045 16.8 0.1 0.03 14.0 0.1 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CCH60756.1 - 0.026 15.0 0.1 0.051 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 CCH60756.1 - 0.052 11.1 0.1 0.067 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RsgA_GTPase PF03193.16 CCH60756.1 - 0.082 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 CCH60756.1 - 0.09 13.3 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CCH60756.1 - 0.12 12.8 0.1 2.4 8.6 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH60756.1 - 0.13 12.6 0.4 0.29 11.4 0.1 1.7 2 0 0 2 2 2 0 AAA domain STE2 PF02116.15 CCH60757.1 - 5.5e-80 268.7 26.5 6.9e-80 268.3 26.5 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR CobD_Cbib PF03186.13 CCH60757.1 - 0.43 9.8 0.0 0.43 9.8 0.0 2.9 2 1 2 4 4 4 0 CobD/Cbib protein DUF1772 PF08592.11 CCH60757.1 - 6.2 7.1 10.4 13 6.1 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Fcf2 PF08698.11 CCH60759.1 - 6.1e-27 93.9 3.7 6.1e-27 93.9 3.7 2.3 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing DUF4706 PF15797.5 CCH60759.1 - 0.018 15.6 4.3 0.53 10.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) FANC_SAP PF18081.1 CCH60759.1 - 0.15 12.3 0.1 29 4.9 0.0 2.6 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain HisK_sensor PF18698.1 CCH60759.1 - 4.2 7.7 8.5 0.18 12.2 0.5 2.5 2 1 0 2 2 2 0 Histidine kinase sensor domain PRP1_N PF06424.12 CCH60759.1 - 9.4 6.6 17.2 0.42 11.0 9.9 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Pyr_redox_2 PF07992.14 CCH60760.1 - 5.4e-69 232.6 3.5 7.3e-69 232.2 3.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCH60760.1 - 1.3e-42 144.5 0.1 3.8e-42 143.0 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCH60760.1 - 3.5e-20 72.3 6.4 5.2e-17 62.2 0.2 3.4 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCH60760.1 - 6.2e-13 48.6 4.2 4.2e-12 45.9 0.5 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CCH60760.1 - 1.3e-11 44.5 3.7 2.2e-11 43.8 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH60760.1 - 1.9e-10 40.8 3.2 5.7e-05 23.3 1.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CCH60760.1 - 3.5e-09 36.3 6.6 9.3e-07 28.4 0.4 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CCH60760.1 - 2.1e-07 30.4 1.4 2.1e-07 30.4 1.4 2.9 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.21 CCH60760.1 - 2.6e-06 26.9 0.9 0.02 14.2 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CCH60760.1 - 1.1e-05 24.3 12.2 0.0003 19.6 0.7 4.1 3 1 1 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.19 CCH60760.1 - 1.5e-05 24.5 5.9 0.041 13.1 0.8 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 CCH60760.1 - 6.5e-05 22.7 10.3 0.14 11.7 0.3 4.0 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 CCH60760.1 - 0.00021 20.6 0.7 0.85 8.7 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CCH60760.1 - 0.00051 19.4 1.0 0.019 14.2 0.1 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 CCH60760.1 - 0.01 15.7 0.1 0.01 15.7 0.1 3.0 3 1 1 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CCH60760.1 - 0.021 14.1 0.1 0.085 12.2 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 CCH60760.1 - 0.11 11.5 0.8 2.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Rep_3 PF01051.21 CCH60760.1 - 0.6 9.9 7.0 4.3 7.1 1.4 2.8 2 1 1 3 3 3 0 Initiator Replication protein Acetyltransf_1 PF00583.25 CCH60761.1 - 5.3e-13 49.2 0.0 6.3e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCH60761.1 - 8.5e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCH60761.1 - 3.7e-09 36.6 0.0 4.6e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mastoparan_2 PF08251.11 CCH60761.1 - 0.013 15.6 0.9 0.041 14.1 0.9 1.8 1 0 0 1 1 1 0 Mastoparan peptide DUF1844 PF08899.11 CCH60761.1 - 0.092 13.1 0.1 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) DUF2781 PF10914.8 CCH60762.1 - 1.8e-30 106.3 10.2 2.1e-30 106.1 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DnaJ_C PF01556.18 CCH60763.1 - 2.1e-24 86.3 0.0 3.9e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCH60763.1 - 1.9e-23 82.4 6.8 2.8e-23 81.8 6.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCH60763.1 - 1.2e-11 44.8 18.9 2.1e-11 44.0 18.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CCH60763.1 - 8.1 6.5 9.3 13 5.9 1.5 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WW PF00397.26 CCH60765.1 - 2.1e-09 37.3 4.4 2.1e-09 37.3 4.4 1.9 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.9 CCH60765.1 - 0.00029 21.0 4.2 0.00037 20.6 4.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) SARAF PF06682.12 CCH60765.1 - 0.063 12.9 4.0 0.09 12.4 4.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Spt20 PF12090.8 CCH60765.1 - 0.98 9.0 5.7 1.2 8.7 5.7 1.1 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 CCH60766.1 - 1.9e-34 117.1 19.5 1.6e-06 28.7 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat CDC4_D PF16856.5 CCH60766.1 - 1e-19 70.2 7.7 3.6e-19 68.4 7.7 2.1 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 CCH60766.1 - 7.4e-12 45.0 1.1 1.7e-11 43.8 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCH60766.1 - 3e-07 30.2 0.4 7.1e-07 29.0 0.4 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CCH60766.1 - 0.0013 19.0 1.3 0.75 10.1 0.0 4.2 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Phage_terminase PF10668.9 CCH60766.1 - 0.14 12.2 0.1 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Phage terminase small subunit BLM10_mid PF16507.5 CCH60767.1 - 1.1e-164 548.9 16.9 1.1e-164 548.9 16.9 2.3 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 CCH60767.1 - 6.8e-30 103.2 0.6 2.9e-29 101.2 0.1 2.4 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 CCH60767.1 - 2.5e-26 91.4 0.0 1.3e-25 89.1 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) UTP15_C PF09384.10 CCH60767.1 - 0.018 14.7 0.2 0.094 12.4 0.1 2.3 2 0 0 2 2 2 0 UTP15 C terminal TAF6_C PF07571.13 CCH60767.1 - 0.034 14.5 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 CCH60767.1 - 0.13 12.6 0.0 7 7.2 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Ras PF00071.22 CCH60768.1 - 1.9e-63 212.9 0.3 2.4e-63 212.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH60768.1 - 1.3e-36 125.5 0.2 2.1e-36 124.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH60768.1 - 1.9e-18 66.5 0.2 2.4e-18 66.2 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH60768.1 - 2.6e-07 30.3 0.1 3e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCH60768.1 - 2.8e-06 27.3 0.2 0.066 13.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CCH60768.1 - 3.6e-06 26.5 0.1 6.1e-06 25.8 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCH60768.1 - 3.9e-06 26.9 0.1 7.2e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH60768.1 - 9.2e-06 25.3 0.2 0.00012 21.6 0.1 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CCH60768.1 - 0.0011 18.5 0.1 0.013 15.0 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 CCH60768.1 - 0.018 14.8 0.1 0.063 13.0 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CCH60768.1 - 0.02 14.4 0.1 0.05 13.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 CCH60768.1 - 0.023 13.8 0.1 0.085 11.9 0.0 1.8 2 1 0 2 2 2 0 MCM P-loop domain G-alpha PF00503.20 CCH60768.1 - 0.028 13.6 2.3 1.6 7.8 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 CCH60768.1 - 0.032 14.0 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH60768.1 - 0.046 14.0 0.0 0.24 11.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA PF00004.29 CCH60768.1 - 0.1 13.0 0.0 0.83 10.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH60768.1 - 0.15 12.4 0.0 0.17 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain VTC PF09359.10 CCH60769.1 - 4.7e-87 291.9 4.6 4.7e-87 291.9 4.6 3.0 2 1 0 2 2 2 1 VTC domain SPX PF03105.19 CCH60769.1 - 9.4e-13 48.8 23.8 4.2e-05 23.6 0.0 4.7 4 1 1 5 5 5 4 SPX domain DUF202 PF02656.15 CCH60769.1 - 3.3e-12 46.7 0.2 7e-12 45.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Peptidase_C48 PF02902.19 CCH60770.1 - 8.5e-38 130.4 0.9 8.5e-38 130.4 0.9 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SIR2 PF02146.17 CCH60771.1 - 3.8e-53 180.0 0.0 1.2e-52 178.4 0.0 1.8 1 1 0 1 1 1 1 Sir2 family rve PF00665.26 CCH60772.1 - 3.8e-07 30.3 0.0 9.4e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Clat_adaptor_s PF01217.20 CCH60773.1 - 1.1e-15 57.9 2.5 2.3e-15 56.8 2.5 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AdoMet_MTase PF07757.13 CCH60774.1 - 1.2e-41 141.5 0.1 2.3e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CCH60774.1 - 0.097 12.5 0.1 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain SUV3_C PF12513.8 CCH60775.1 - 6.6e-14 51.6 0.7 1.4e-13 50.5 0.7 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CCH60775.1 - 1.1e-13 51.5 0.0 3.2e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4771 PF15995.5 CCH60775.1 - 0.034 14.4 4.7 0.057 13.7 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) Pkinase PF00069.25 CCH60776.1 - 4.8e-38 131.0 0.0 2.2e-35 122.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60776.1 - 1.6e-20 73.5 0.0 4.1e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCH60776.1 - 3e-07 30.1 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sybindin PF04099.12 CCH60777.1 - 1.5e-31 109.2 0.1 7.2e-17 61.6 0.0 2.5 2 1 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 CCH60777.1 - 2.3e-07 31.0 0.0 2.7e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region RMI1_N PF08585.12 CCH60778.1 - 1.3e-12 47.9 0.0 1.3e-12 47.9 0.0 2.0 1 1 1 2 2 2 1 RecQ mediated genome instability protein MTHFR PF02219.17 CCH60779.1 - 1e-103 346.6 0.0 1.4e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Macoilin PF09726.9 CCH60779.1 - 0.22 10.0 6.4 0.29 9.7 6.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4196 PF13846.6 CCH60779.1 - 0.8 9.9 11.5 6.4 7.0 8.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4196) Tir_receptor_C PF07489.11 CCH60779.1 - 4.7 7.1 9.4 8.2 6.3 9.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus ERCC4 PF02732.15 CCH60780.1 - 2.3e-23 83.1 0.1 2.3e-23 83.1 0.1 2.5 2 0 0 2 2 2 1 ERCC4 domain Totivirus_coat PF05518.11 CCH60780.1 - 0.044 11.9 0.0 0.063 11.3 0.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein DEAD PF00270.29 CCH60781.1 - 7.1e-49 165.9 0.4 2.1e-47 161.1 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60781.1 - 1.3e-31 109.2 1.3 2.2e-29 102.0 0.1 3.4 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH60781.1 - 4.4e-07 30.1 0.4 2e-06 27.9 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Torus PF16131.5 CCH60782.1 - 3.1e-33 114.7 0.3 7.7e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 CCH60782.1 - 0.00069 19.4 0.8 0.0019 17.9 0.1 2.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CCH60782.1 - 0.0041 17.1 4.0 0.0041 17.1 4.0 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CCH60782.1 - 0.015 15.1 4.7 0.033 14.0 4.7 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 CCH60782.1 - 0.57 10.2 6.2 0.16 12.0 3.2 1.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CCH60782.1 - 5.2 7.7 6.1 2 9.0 1.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Zn-C2H2_12 PF18112.1 CCH60783.1 - 0.13 12.7 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain TFIIF_beta PF02270.15 CCH60784.1 - 0.058 13.5 0.2 0.34 11.1 0.2 2.2 2 0 0 2 2 2 0 TFIIF, beta subunit HTH domain TPP_enzyme_N PF02776.18 CCH60785.1 - 1.2e-32 112.9 0.0 1.9e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH60785.1 - 2.2e-27 95.5 0.0 5.3e-26 91.0 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH60785.1 - 1e-13 51.4 0.0 3.2e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CCH60785.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SKN1 PF03935.15 CCH60786.1 - 1.3e-248 825.5 6.0 1.9e-248 824.9 6.0 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF1438 PF07270.11 CCH60786.1 - 0.081 13.0 1.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Apc15p PF05841.11 CCH60786.1 - 4.9 8.0 11.8 2.7 8.8 7.9 2.6 2 0 0 2 2 2 0 Apc15p protein MULE PF10551.9 CCH60788.1 - 2.3e-08 34.3 0.0 6.7e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.18 CCH60788.1 - 0.00011 21.3 0.7 0.00017 20.6 0.7 1.2 1 0 0 1 1 1 1 Transposase, Mutator family HOCHOB PF17943.1 CCH60788.1 - 0.067 13.9 0.5 0.21 12.3 0.5 1.8 1 0 0 1 1 1 0 Homeobox-cysteine loop-homeobox STN1_2 PF09170.10 CCH60788.1 - 0.11 12.6 1.3 0.31 11.2 0.7 2.1 2 1 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 NDC10_II PF16787.5 CCH60789.1 - 4.9e-102 341.2 14.6 4.9e-102 341.2 14.6 2.3 3 0 0 3 3 3 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CCH60789.1 - 9.6e-15 54.7 0.2 3.6e-14 52.8 0.2 2.1 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MFS_1 PF07690.16 CCH60790.1 - 8.1e-33 113.8 40.2 1.8e-32 112.6 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH60790.1 - 3.6e-10 39.3 23.5 1.1e-09 37.7 23.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter SH3_9 PF14604.6 CCH60791.1 - 2.7e-11 43.1 0.0 6.1e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCH60791.1 - 4.2e-11 42.3 0.1 7.9e-11 41.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCH60791.1 - 8.5e-11 41.4 0.1 1.6e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain UBA_2 PF08587.11 CCH60791.1 - 0.14 12.3 0.3 40 4.4 0.0 3.1 3 0 0 3 3 3 0 Ubiquitin associated domain (UBA) PRCC PF10253.9 CCH60791.1 - 1.6 9.5 6.2 2.5 8.9 6.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Proteasome PF00227.26 CCH60792.1 - 1.2e-57 194.5 0.1 1.5e-57 194.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH60792.1 - 5.2e-12 45.2 0.9 8.4e-12 44.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FF PF01846.19 CCH60793.1 - 3.8e-11 43.0 1.6 8.2e-10 38.7 0.6 2.9 3 0 0 3 3 3 1 FF domain NESP55 PF06390.12 CCH60793.1 - 0.21 11.1 4.5 0.34 10.5 4.5 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pet20 PF08692.10 CCH60794.1 - 7.2e-17 62.3 0.1 8.2e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Band_7 PF01145.25 CCH60795.1 - 4.9e-24 85.3 5.5 9.7e-24 84.3 5.5 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CCH60795.1 - 0.0067 15.5 0.5 0.0089 15.1 0.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CCH60795.1 - 0.02 14.6 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family MARVEL PF01284.23 CCH60796.1 - 3.7e-27 95.1 3.9 4.7e-27 94.8 3.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2721 PF11026.8 CCH60796.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Tetraspanin PF00335.20 CCH60796.1 - 1.7 8.3 5.3 0.75 9.5 1.1 2.1 2 1 0 2 2 2 0 Tetraspanin family BAR_2 PF10455.9 CCH60798.1 - 3.8e-89 298.6 17.7 3.8e-89 298.6 17.7 1.4 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Herpes_UL33 PF03581.13 CCH60798.1 - 0.048 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL33-like protein BAR PF03114.18 CCH60798.1 - 0.066 12.8 22.8 0.043 13.5 8.4 4.0 3 2 2 5 5 5 0 BAR domain Fibin PF15819.5 CCH60798.1 - 4 7.2 8.6 1.3 8.8 2.7 2.5 1 1 1 2 2 2 0 Fin bud initiation factor homologue TANGO2 PF05742.12 CCH60799.1 - 2.9e-62 211.0 0.0 3.4e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Mis12 PF05859.12 CCH60799.1 - 0.033 14.2 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Mis12 protein Fer2_2 PF01799.20 CCH60799.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 [2Fe-2S] binding domain MFS_1 PF07690.16 CCH60800.1 - 1.7e-24 86.4 28.2 2.6e-24 85.8 28.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CCH60800.1 - 3.8e-05 23.2 4.4 3.8e-05 23.2 4.4 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3792 PF12670.7 CCH60800.1 - 0.021 15.0 0.9 0.021 15.0 0.9 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) DUF63 PF01889.17 CCH60800.1 - 0.37 10.9 4.6 0.22 11.7 1.0 2.3 2 1 0 2 2 2 0 Membrane protein of unknown function DUF63 SSB PF00436.25 CCH60801.1 - 1.1e-20 73.6 0.0 1.3e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family muHD PF10291.9 CCH60802.1 - 2e-69 234.0 0.0 4.1e-69 233.0 0.0 1.6 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mannosyl_trans3 PF11051.8 CCH60803.1 - 3.1e-83 279.3 0.0 5.9e-83 278.4 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Ribosomal_L39 PF00832.20 CCH60804.1 - 4.2e-22 77.5 12.7 4.9e-22 77.3 12.7 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S8 PF00410.19 CCH60805.1 - 1.6e-23 83.0 0.4 2.4e-23 82.4 0.4 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.19 CCH60806.1 - 4.7e-46 155.7 1.8 5.9e-46 155.4 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CCH60806.1 - 0.045 13.1 0.4 0.055 12.8 0.4 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme NFACT-R_1 PF05670.13 CCH60806.1 - 0.15 12.8 0.0 0.18 12.4 0.0 1.1 1 0 0 1 1 1 0 NFACT protein RNA binding domain SOP4 PF17081.5 CCH60807.1 - 2e-90 301.9 0.6 2.3e-90 301.7 0.6 1.0 1 0 0 1 1 1 1 Suppressor of PMA 1-7 protein Beach PF02138.18 CCH60808.1 - 2.5e-116 387.9 0.5 2.5e-116 387.9 0.5 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 CCH60808.1 - 2.7e-09 37.0 0.0 3.4e-08 33.5 0.0 3.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH TPT PF03151.16 CCH60809.1 - 1.1e-27 97.2 20.7 1.8e-14 53.8 1.8 3.4 3 1 0 3 3 3 3 Triose-phosphate Transporter family EamA PF00892.20 CCH60809.1 - 0.072 13.3 42.8 0.13 12.4 5.3 4.4 4 1 1 5 5 5 0 EamA-like transporter family AAA PF00004.29 CCH60810.1 - 4.5e-11 43.3 1.2 4.1e-10 40.2 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH60810.1 - 2.6e-09 37.4 0.0 7.9e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 CCH60810.1 - 2.1e-06 27.6 0.6 8.4e-06 25.7 0.2 2.2 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 CCH60810.1 - 3.3e-06 27.6 0.0 2.7e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CCH60810.1 - 0.00056 19.5 0.2 0.067 12.7 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CCH60810.1 - 0.00083 19.3 0.5 0.0024 17.8 0.1 1.9 1 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCH60810.1 - 0.0036 17.3 0.2 0.26 11.3 0.2 3.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH60810.1 - 0.0081 16.5 0.0 0.033 14.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CCH60810.1 - 0.016 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 CCH60810.1 - 0.066 13.0 4.1 0.079 12.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCH60810.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCH60810.1 - 0.21 11.3 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 CCH60811.1 - 8e-80 268.5 33.2 1e-79 268.2 33.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.12 CCH60812.1 - 4.8e-152 507.6 61.2 6e-152 507.3 61.2 1.0 1 0 0 1 1 1 1 Mpp10 protein SbcD_C PF12320.8 CCH60812.1 - 2.1 8.7 7.7 0.2 12.0 1.1 2.7 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain NOC3p PF07540.11 CCH60813.1 - 1.5e-27 95.9 0.1 1.5e-27 95.9 0.1 3.7 3 1 0 3 3 3 2 Nucleolar complex-associated protein CBF PF03914.17 CCH60813.1 - 4.7e-21 75.6 0.1 4.7e-21 75.6 0.1 2.5 3 0 0 3 3 3 1 CBF/Mak21 family Candida_ALS_N PF11766.8 CCH60814.1 - 1.8e-70 237.0 6.1 1.8e-70 237.0 6.1 2.7 2 1 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.18 CCH60814.1 - 3.3e-38 129.7 103.4 1.9e-14 53.6 29.6 9.3 8 1 1 9 9 9 3 Flocculin repeat Candida_ALS_N PF11766.8 CCH60815.1 - 6.6e-69 231.9 3.2 1.2e-68 231.1 3.2 1.4 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.18 CCH60815.1 - 4.4e-07 30.0 21.5 6.5e-05 23.1 7.3 4.3 5 0 0 5 5 5 2 Flocculin repeat Adaptin_N PF01602.20 CCH60816.1 - 1.9e-91 307.2 20.8 2.4e-91 306.9 20.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCH60816.1 - 6.5e-15 55.5 2.6 6.5e-15 55.5 2.6 3.8 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCH60816.1 - 3e-06 27.5 0.0 0.78 10.2 0.0 3.7 2 1 1 3 3 3 3 HEAT repeats DUF3385 PF11865.8 CCH60816.1 - 0.033 14.1 1.2 14 5.6 0.2 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) VHS PF00790.19 CCH60816.1 - 0.065 13.1 2.1 0.38 10.6 0.4 3.3 2 1 1 3 3 3 0 VHS domain HEAT PF02985.22 CCH60816.1 - 0.19 12.1 0.8 64 4.2 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat RTP1_C1 PF10363.9 CCH60816.1 - 1.9 8.7 5.1 4 7.7 0.7 3.5 2 1 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Response_reg PF00072.24 CCH60817.1 - 6.4e-19 68.2 0.0 8.5e-13 48.5 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Fimbrial_K88 PF02432.15 CCH60817.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Cyt-b5 PF00173.28 CCH60818.1 - 1.9e-17 63.1 0.4 1.9e-17 63.1 0.4 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CCH60818.1 - 7e-14 52.3 15.3 7e-14 52.3 15.3 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Zds_C PF08632.10 CCH60819.1 - 1.7e-28 98.1 1.7 4e-28 96.9 1.7 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CPBP PF02517.16 CCH60820.1 - 5.8e-15 55.4 3.2 1.6e-14 54.0 3.2 1.7 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Ubie_methyltran PF01209.18 CCH60821.1 - 7.2e-99 329.8 1.0 8.5e-99 329.6 1.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CCH60821.1 - 6e-15 55.7 0.0 1.6e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH60821.1 - 3.7e-14 53.1 0.0 9.8e-14 51.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH60821.1 - 7.8e-13 48.5 0.1 1.5e-12 47.5 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH60821.1 - 2.4e-10 41.0 0.1 4.3e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH60821.1 - 4.1e-07 30.0 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CCH60821.1 - 0.00092 19.2 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CCH60821.1 - 0.0038 17.1 0.0 0.041 13.7 0.0 2.5 2 1 0 3 3 3 1 Hypothetical methyltransferase ADH_zinc_N PF00107.26 CCH60821.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GidB PF02527.15 CCH60821.1 - 0.12 11.7 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G EutA PF06277.11 CCH60821.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA Bul1_N PF04425.12 CCH60822.1 - 4.5e-161 536.6 2.5 4.5e-161 536.6 2.5 3.1 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.12 CCH60822.1 - 9.5e-96 320.4 16.2 9.5e-96 320.4 16.2 2.9 3 1 0 3 3 3 1 Bul1 C terminus ubiquitin PF00240.23 CCH60823.1 - 2.5e-22 78.4 0.1 4.2e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCH60823.1 - 4.3e-09 36.1 0.2 7.5e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCH60823.1 - 5.2e-05 23.6 0.1 0.00012 22.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain UBA PF00627.31 CCH60823.1 - 9.3e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 CCH60823.1 - 0.00037 20.6 0.3 0.0016 18.5 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CCH60823.1 - 0.0085 16.1 0.5 5 7.2 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin-like domain GerD PF17898.1 CCH60823.1 - 0.014 15.3 1.7 0.03 14.3 1.7 1.5 1 0 0 1 1 1 0 Spore germination GerD central core domain TBK1_ULD PF18396.1 CCH60823.1 - 0.03 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain HOIP-UBA PF16678.5 CCH60823.1 - 0.034 14.2 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair YukD PF08817.10 CCH60823.1 - 0.13 13.0 0.0 0.43 11.3 0.0 2.0 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF2407 PF10302.9 CCH60823.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UN_NPL4 PF11543.8 CCH60823.1 - 0.14 12.6 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 PAS_4 PF08448.10 CCH60823.1 - 0.16 12.3 0.1 2 8.7 0.0 2.5 2 1 1 3 3 3 0 PAS fold Mucin PF01456.17 CCH60823.1 - 2.1 8.3 24.3 3.4 7.7 2.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.11 CCH60823.1 - 3.7 5.6 20.3 0.17 10.0 4.5 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 zf-CCHC PF00098.23 CCH60824.1 - 0.00012 22.0 3.6 0.00022 21.2 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle YgbA_NO PF11756.8 CCH60824.1 - 0.012 16.0 3.0 0.023 15.1 3.0 1.6 1 1 0 1 1 1 0 Nitrous oxide-stimulated promoter TSSC4 PF15264.6 CCH60824.1 - 0.13 12.5 1.6 5 7.4 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 TAF8_C PF10406.9 CCH60825.1 - 8e-17 61.5 0.1 8e-17 61.5 0.1 2.7 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term NIF PF03031.18 CCH60826.1 - 1.7e-23 83.1 0.9 2.6e-22 79.3 0.0 2.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CCH60826.1 - 1.7e-11 44.4 0.4 5.1e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCH60826.1 - 3.1e-06 27.1 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CCH60826.1 - 0.0018 18.6 0.0 0.0052 17.2 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CCH60826.1 - 0.035 14.4 1.4 0.049 13.9 0.1 1.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain ATP-synt_J PF04911.12 CCH60826.1 - 0.1 12.2 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 ATP synthase j chain InvH PF04741.12 CCH60826.1 - 0.12 12.3 5.9 4.4 7.2 1.1 2.8 2 1 1 3 3 3 0 InvH outer membrane lipoprotein BRCT_3 PF18428.1 CCH60826.1 - 0.16 12.0 0.1 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain MFS_1 PF07690.16 CCH60827.1 - 1.4e-32 113.0 53.0 1.4e-32 113.0 53.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Ac76 PF05814.11 CCH60827.1 - 0.045 13.8 1.0 0.18 11.9 1.0 2.0 1 0 0 1 1 1 0 Orf76 (Ac76) Muted PF14942.6 CCH60827.1 - 0.29 11.5 0.7 0.47 10.8 0.7 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein MFS_1 PF07690.16 CCH60828.1 - 1.4e-36 126.2 57.6 2.7e-34 118.7 57.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Ac76 PF05814.11 CCH60828.1 - 0.51 10.4 3.2 0.89 9.6 1.5 2.4 2 0 0 2 2 2 0 Orf76 (Ac76) NADH-u_ox-rdase PF10785.9 CCH60828.1 - 4.1 8.1 6.3 1.2e+02 3.5 2.2 3.8 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit TraQ PF09679.10 CCH60828.1 - 4.7 7.2 7.4 26 4.8 0.2 3.4 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) Oxidored_FMN PF00724.20 CCH60829.1 - 5.6e-120 400.7 0.0 6.4e-120 400.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SinI PF08671.10 CCH60829.1 - 0.54 10.1 2.7 0.92 9.4 0.3 2.5 2 1 0 2 2 2 0 Anti-repressor SinI Exo_endo_phos PF03372.23 CCH60830.1 - 1e-28 100.5 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyr_redox_2 PF07992.14 CCH60832.1 - 1.1e-48 166.0 0.0 1.4e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCH60832.1 - 1.7e-12 47.7 0.0 2.6e-09 37.5 0.1 2.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCH60832.1 - 0.0054 16.0 0.2 3.9 6.6 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase SQS_PSY PF00494.19 CCH60833.1 - 2.2e-36 125.7 0.0 2.7e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Cut8 PF08559.10 CCH60833.1 - 0.075 12.6 0.6 0.19 11.3 0.6 1.7 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Oxidored_FMN PF00724.20 CCH60834.1 - 2.4e-71 240.8 0.0 2.7e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 CCH60835.1 - 7.6e-31 107.6 0.0 8.3e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PX PF00787.24 CCH60836.1 - 2.3e-17 63.0 0.8 2.3e-17 63.0 0.8 2.8 3 0 0 3 3 3 1 PX domain LemA PF04011.12 CCH60836.1 - 0.075 12.9 0.4 0.075 12.9 0.4 2.9 2 0 0 2 2 2 0 LemA family DUF948 PF06103.11 CCH60836.1 - 0.13 12.6 7.0 0.052 13.8 1.4 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 CCH60836.1 - 0.3 11.6 21.4 0.034 14.6 6.8 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Phasin PF05597.11 CCH60836.1 - 3.1 7.8 7.9 7.2 6.6 1.2 2.9 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Uds1 PF15456.6 CCH60836.1 - 7.7 6.7 6.7 24 5.1 0.6 3.3 3 0 0 3 3 3 0 Up-regulated During Septation DALR_1 PF05746.15 CCH60836.1 - 8.2 6.6 7.7 1.5 9.0 0.5 2.9 2 1 0 2 2 2 0 DALR anticodon binding domain dCMP_cyt_deam_1 PF00383.23 CCH60837.1 - 5.2e-23 80.8 0.4 8.3e-23 80.2 0.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCH60837.1 - 3.1e-18 65.8 0.0 4.2e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 CCH60837.1 - 0.00021 21.4 0.1 0.00051 20.2 0.1 1.6 2 0 0 2 2 2 1 APOBEC3 APOBEC_N PF08210.11 CCH60837.1 - 0.00028 20.8 0.1 0.00044 20.2 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 CCH60837.1 - 0.00031 20.9 0.2 0.0012 19.0 0.1 1.8 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Inv-AAD PF18785.1 CCH60837.1 - 0.00093 19.1 0.1 0.0015 18.4 0.1 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC2 PF18772.1 CCH60837.1 - 0.00097 19.2 0.1 0.0016 18.5 0.1 1.3 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 CCH60837.1 - 0.001 19.2 0.2 0.0016 18.6 0.2 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 CCH60837.1 - 0.009 16.1 2.7 0.16 12.0 2.7 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC4_like PF18774.1 CCH60837.1 - 0.019 14.9 0.1 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NAD2 PF18782.1 CCH60837.1 - 0.043 13.9 0.1 0.065 13.3 0.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Toxin-deaminase PF14424.6 CCH60837.1 - 0.082 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases HSP70 PF00012.20 CCH60838.1 - 5.5e-265 880.2 12.8 6.3e-265 880.0 12.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH60838.1 - 2.5e-18 66.0 2.7 3.5e-17 62.2 0.8 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CCH60838.1 - 0.00035 20.9 2.9 0.57 10.6 0.1 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CCH60838.1 - 0.00064 19.1 1.2 0.11 11.8 0.1 3.2 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 CCH60838.1 - 0.0044 16.6 0.1 0.057 12.9 0.1 2.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Sec34 PF04136.15 CCH60838.1 - 0.0063 16.4 1.6 0.016 15.1 1.6 1.6 1 0 0 1 1 1 1 Sec34-like family Enolase_N PF03952.16 CCH60838.1 - 0.0076 16.4 1.2 0.78 9.9 0.0 2.9 2 1 0 2 2 2 1 Enolase, N-terminal domain DUF5300 PF17224.3 CCH60838.1 - 0.077 13.3 4.0 12 6.2 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) FHA PF00498.26 CCH60839.1 - 8.2e-08 32.5 0.1 1.6e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCH60839.1 - 0.016 15.5 0.3 0.057 13.7 0.3 1.9 1 1 1 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain DEAD PF00270.29 CCH60840.1 - 1.5e-46 158.4 0.1 8.3e-46 155.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60840.1 - 2.1e-25 89.2 0.1 8.4e-25 87.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCH60840.1 - 3e-20 72.2 0.0 6.4e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCH60840.1 - 4.2e-05 23.6 0.0 4.2e-05 23.6 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Cyclin_N PF00134.23 CCH60841.1 - 1e-07 31.7 2.0 2.2e-07 30.7 2.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain PPTA PF01239.22 CCH60843.1 - 2.6e-34 115.9 22.0 4.7e-07 29.3 3.7 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.6 CCH60843.1 - 0.051 13.3 0.5 3 7.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3950) HORMA PF02301.18 CCH60844.1 - 1.1e-18 67.6 0.0 1.4e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 HORMA domain YojJ PF10372.9 CCH60844.1 - 0.025 14.7 0.1 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus VPS53_C PF16854.5 CCH60845.1 - 2.4e-71 239.8 9.6 2.4e-71 239.8 9.6 3.5 3 1 1 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus Vps53_N PF04100.12 CCH60845.1 - 1.9e-67 227.9 30.4 6.8e-67 226.1 30.4 2.0 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF1729 PF08354.10 CCH60845.1 - 0.018 13.9 0.2 0.018 13.9 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) BORCS7 PF16088.5 CCH60845.1 - 1.4 9.2 10.7 2.9 8.2 0.1 3.9 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 KH_1 PF00013.29 CCH60847.1 - 2.4e-33 113.8 5.0 1.8e-12 46.9 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCH60847.1 - 2.7e-08 33.5 0.9 0.1 12.4 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CCH60847.1 - 0.00012 21.9 0.4 0.31 10.9 0.0 3.5 3 0 0 3 3 3 2 KH domain PQQ PF01011.21 CCH60849.1 - 0.071 13.1 0.0 0.26 11.3 0.0 2.0 1 0 0 1 1 1 0 PQQ enzyme repeat CUE PF02845.16 CCH60850.1 - 7e-07 28.8 0.2 2.4e-06 27.2 0.2 2.0 1 0 0 1 1 1 1 CUE domain Snapin_Pallidin PF14712.6 CCH60850.1 - 3.8 8.0 10.0 1 9.8 0.9 3.0 3 0 0 3 3 3 0 Snapin/Pallidin Pox_MCEL PF03291.16 CCH60851.1 - 4.5e-100 335.0 0.0 7.7e-100 334.2 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CCH60851.1 - 6.2e-11 42.9 0.0 1.3e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH60851.1 - 1e-07 32.6 0.1 4.9e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH60851.1 - 8.4e-07 29.6 0.0 2.6e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH60851.1 - 2e-05 24.4 0.0 5e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH60851.1 - 4.5e-05 23.3 0.0 8.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CCH60851.1 - 0.0018 17.5 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family CCDC71L PF15374.6 CCH60851.1 - 0.07 12.4 5.9 0.27 10.5 6.9 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L DUF2576 PF10845.8 CCH60851.1 - 0.12 12.0 0.9 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Use1 PF09753.9 CCH60851.1 - 0.81 9.4 13.6 1.3 8.7 13.6 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 TMEM214 PF10151.9 CCH60851.1 - 3.1 6.1 6.6 4.3 5.7 6.6 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF1509 PF07420.11 CCH60851.1 - 3.2 6.6 8.4 4.6 6.1 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DEAD PF00270.29 CCH60852.1 - 7.7e-44 149.5 0.0 3.1e-43 147.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH60852.1 - 6.2e-21 74.8 0.1 3.7e-20 72.3 0.1 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH60852.1 - 1.5e-07 31.6 0.0 1.5e-07 31.6 0.0 4.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Noggin PF05806.12 CCH60853.1 - 2.2 8.1 5.9 2.8 7.8 5.9 1.1 1 0 0 1 1 1 0 Noggin LptF_LptG PF03739.14 CCH60853.1 - 2.4 6.9 3.0 3.3 6.5 3.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG PAS PF00989.25 CCH60855.1 - 9.7e-16 57.8 0.0 3.5e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 CCH60855.1 - 6.3e-05 23.0 8.6 0.00012 22.1 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.12 CCH60855.1 - 0.085 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold Mito_carr PF00153.27 CCH60856.1 - 9.2e-47 156.9 4.6 1.3e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FoP_duplication PF13865.6 CCH60857.1 - 4.2e-06 27.2 0.8 6.7e-06 26.6 0.8 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 CCH60857.1 - 0.0011 18.8 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B5 PF03484.15 CCH60857.1 - 0.031 14.6 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase B5 domain PFU PF09070.11 CCH60858.1 - 3.3e-42 143.3 2.6 3.7e-42 143.2 0.9 2.0 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 CCH60858.1 - 3.7e-31 108.4 0.0 4.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 CCH60858.1 - 4.5e-22 77.9 11.5 0.0054 17.5 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 CCH60858.1 - 0.00049 20.1 0.6 2.7 8.1 0.0 3.7 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Herpes_glycop_H PF02489.16 CCH60858.1 - 0.093 11.2 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain Proteasome_A_N PF10584.9 CCH60858.1 - 0.61 9.8 0.0 0.61 9.8 0.0 2.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Syja_N PF02383.18 CCH60859.1 - 4.2e-80 269.4 1.7 6.3e-80 268.9 1.7 1.2 1 0 0 1 1 1 1 SacI homology domain Cofilin_ADF PF00241.20 CCH60859.1 - 0.025 14.4 0.1 0.056 13.2 0.1 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein IGPS PF00218.21 CCH60860.1 - 4.3e-81 271.8 0.0 5.6e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 CCH60860.1 - 1.7e-52 178.0 0.0 2.7e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCH60860.1 - 9.6e-09 35.3 0.1 3.3e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 Peripla_BP_2 PF01497.18 CCH60860.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein NanE PF04131.14 CCH60860.1 - 0.0091 15.2 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.19 CCH60860.1 - 0.14 11.9 0.2 0.46 10.2 0.0 1.9 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiF PF00899.21 CCH60861.1 - 5.1e-108 360.0 0.0 6.3e-75 251.7 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CCH60861.1 - 1.7e-87 293.5 0.2 2.6e-87 292.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CCH60861.1 - 1.1e-32 112.6 0.1 3.4e-32 111.0 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CCH60861.1 - 4e-27 94.2 0.6 1e-26 92.9 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CCH60861.1 - 1.5e-23 82.8 0.1 3.8e-23 81.5 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle PEMT PF04191.13 CCH60862.1 - 3.6e-34 117.3 0.7 3.6e-34 117.3 0.7 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase HEAT_2 PF13646.6 CCH60864.1 - 3.3e-34 117.1 0.0 2.7e-16 59.7 0.0 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CCH60864.1 - 2.3e-18 64.9 0.0 0.00026 21.4 0.2 5.9 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CCH60864.1 - 1.7e-11 43.3 1.2 0.17 12.2 0.0 5.4 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 CCH60864.1 - 0.0018 18.7 1.5 3.5 8.2 0.1 3.9 2 2 2 4 4 4 3 HEAT-like repeat FAT PF02259.23 CCH60866.1 - 1.8e-140 468.1 0.1 1.8e-140 468.1 0.1 3.1 3 1 1 4 4 4 1 FAT domain PI3_PI4_kinase PF00454.27 CCH60866.1 - 3.7e-71 239.9 0.0 7.9e-71 238.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CCH60866.1 - 4.5e-68 228.2 21.9 3.8e-65 218.7 0.7 6.1 5 1 1 6 6 6 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CCH60866.1 - 1.7e-43 147.1 3.8 3.6e-43 146.0 0.5 3.1 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CCH60866.1 - 5.4e-17 61.3 0.3 1.4e-16 60.0 0.3 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CCH60866.1 - 4.2e-12 46.3 2.4 0.3 11.5 0.0 8.4 8 1 1 9 9 9 2 HEAT repeats HEAT_EZ PF13513.6 CCH60866.1 - 4.2e-09 36.7 0.0 0.0093 16.5 0.0 8.0 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CCH60866.1 - 1.3e-06 28.1 1.7 0.026 14.8 0.0 7.0 8 0 0 8 8 8 1 HEAT repeat DUF3437 PF11919.8 CCH60866.1 - 0.0037 17.2 0.2 5.2 7.1 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) HrpB1_HrpK PF09613.10 CCH60866.1 - 0.027 14.1 0.0 0.15 11.7 0.0 2.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Imm30 PF15565.6 CCH60866.1 - 0.08 13.0 0.3 0.89 9.7 0.0 2.9 2 0 0 2 2 2 0 Immunity protein 30 CLASP_N PF12348.8 CCH60866.1 - 0.44 10.1 10.2 2.9 7.4 0.0 5.5 4 1 2 6 6 6 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 CCH60866.1 - 0.54 10.9 7.1 54 4.5 0.0 5.9 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Actin PF00022.19 CCH60867.1 - 3.7e-90 302.5 0.0 9.9e-88 294.5 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCH60867.1 - 1.6e-06 27.2 0.0 0.0032 16.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCH60867.1 - 0.00021 21.7 0.0 0.00066 20.1 0.0 1.9 2 1 0 2 2 2 1 Cell division protein FtsA Cpn60_TCP1 PF00118.24 CCH60868.1 - 3.4e-152 507.5 4.6 3.9e-152 507.3 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 CCH60868.1 - 0.0038 17.1 1.5 3.2 7.6 0.1 2.9 2 1 0 2 2 2 2 Chloramphenicol phosphotransferase-like protein Cation_ATPase PF13246.6 CCH60868.1 - 0.055 13.6 0.1 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) TFIIS_C PF01096.18 CCH60869.1 - 8e-18 64.0 7.7 1.3e-17 63.4 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCH60869.1 - 6.8e-13 48.3 9.1 5.5e-10 39.0 1.1 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 CCH60869.1 - 2.1e-05 24.5 7.0 0.0068 16.4 0.4 2.7 2 1 1 3 3 3 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 CCH60869.1 - 0.0032 17.4 3.2 0.043 13.8 0.6 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 CCH60869.1 - 0.0052 16.3 10.5 0.024 14.2 2.8 2.8 2 2 0 2 2 2 2 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 CCH60869.1 - 0.0092 15.7 13.9 0.32 10.8 0.4 4.2 4 0 0 4 4 4 1 zinc-ribbon domain zinc_ribbon_4 PF13717.6 CCH60869.1 - 0.011 15.6 11.1 0.83 9.6 0.8 3.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-TFIIB PF13453.6 CCH60869.1 - 0.015 14.6 0.7 0.015 14.6 0.7 2.2 2 0 0 2 2 2 0 Transcription factor zinc-finger DpnI PF06044.12 CCH60869.1 - 0.025 14.2 4.5 0.52 9.9 0.6 2.1 1 1 1 2 2 2 0 Dam-replacing family Ogr_Delta PF04606.12 CCH60869.1 - 0.032 14.2 6.5 0.18 11.8 3.6 2.6 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.6 CCH60869.1 - 0.033 14.6 4.3 2.1 8.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 CCH60869.1 - 0.037 14.1 11.2 2.3 8.4 0.4 3.3 3 0 0 3 3 3 0 Zinc ribbon domain TackOD1 PF18551.1 CCH60869.1 - 0.04 13.6 6.5 0.43 10.2 0.5 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 C1_1 PF00130.22 CCH60869.1 - 0.062 13.2 3.5 1.2 9.1 0.3 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_LEF5_C PF11792.8 CCH60869.1 - 0.078 12.7 3.6 0.27 10.9 0.0 2.8 3 0 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.19 CCH60869.1 - 0.082 12.9 8.3 0.35 10.9 4.6 2.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 CCH60869.1 - 0.2 11.7 8.2 5.2 7.2 0.4 2.8 1 1 1 2 2 2 0 Transposase zinc-binding domain DUF2072 PF09845.9 CCH60869.1 - 0.4 11.0 0.2 0.4 11.0 0.2 2.7 1 1 1 3 3 3 0 Zn-ribbon containing protein zf-C2HC5 PF06221.13 CCH60869.1 - 0.53 10.3 6.1 1 9.4 0.6 2.8 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zinc-ribbons_6 PF07191.12 CCH60869.1 - 0.58 10.2 9.9 2.7 8.0 1.4 2.7 2 2 0 2 2 2 0 zinc-ribbons zf-RING_5 PF14634.6 CCH60869.1 - 1.1 9.3 7.0 3 7.9 1.0 2.7 3 0 0 3 3 3 0 zinc-RING finger domain DUF951 PF06107.11 CCH60869.1 - 1.6 8.7 4.6 7.2 6.6 0.0 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF951) RecR PF02132.15 CCH60869.1 - 2 8.0 5.8 21 4.8 2.8 2.8 2 1 0 2 2 2 0 RecR protein zf-C4_Topoisom PF01396.19 CCH60869.1 - 2 8.2 12.6 0.096 12.5 3.2 3.2 3 1 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger CpXC PF14353.6 CCH60869.1 - 2.4 8.3 11.0 0.38 10.8 1.0 3.1 1 1 2 3 3 3 0 CpXC protein zf-ribbon_3 PF13248.6 CCH60869.1 - 3.1 7.4 16.3 1.8 8.1 0.6 4.2 4 0 0 4 4 4 0 zinc-ribbon domain NOB1_Zn_bind PF08772.11 CCH60869.1 - 4.3 7.6 10.1 3.3 7.9 1.9 3.0 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-ISL3 PF14690.6 CCH60869.1 - 5.2 7.8 9.0 8.3 7.2 0.1 3.3 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 OrfB_Zn_ribbon PF07282.11 CCH60869.1 - 5.2 7.1 8.6 26 4.8 2.7 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-AN1 PF01428.16 CCH60869.1 - 5.6 7.2 9.9 33 4.8 0.1 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger Nudix_N_2 PF14803.6 CCH60869.1 - 6.1 6.9 10.7 7.8 6.5 1.4 3.7 3 1 0 3 3 3 0 Nudix N-terminal zinc_ribbon_15 PF17032.5 CCH60869.1 - 9.2 7.1 12.5 4.1 8.2 5.1 3.1 1 1 0 2 2 2 0 zinc-ribbon family PRCC PF10253.9 CCH60870.1 - 0.0071 17.2 9.5 0.012 16.4 9.5 1.4 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2771 PF10969.8 CCH60870.1 - 0.012 15.6 0.1 0.014 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) LicD PF04991.13 CCH60871.1 - 2e-47 162.3 3.2 2e-47 162.3 3.2 3.6 3 0 0 3 3 3 1 LicD family SRP-alpha_N PF04086.13 CCH60871.1 - 0.21 11.5 33.6 0.077 12.9 30.0 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal PTPRCAP PF15713.5 CCH60871.1 - 0.43 10.8 28.6 1 9.6 28.6 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF913 PF06025.12 CCH60871.1 - 4 6.3 13.7 10 5.0 13.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_11 PF13086.6 CCH60871.1 - 5.1 6.8 20.6 8.8 6.0 18.9 2.2 2 0 0 2 2 2 0 AAA domain Endostatin PF06482.11 CCH60871.1 - 5.7 6.3 11.7 17 4.8 11.7 1.8 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin HLH PF00010.26 CCH60872.1 - 1.2e-12 47.6 5.7 2e-12 46.9 4.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Flu_NS2 PF00601.19 CCH60872.1 - 0.22 11.9 2.3 15 5.9 0.2 2.4 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) Pkinase PF00069.25 CCH60873.1 - 2.3e-40 138.7 0.0 4.6e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60873.1 - 7.5e-16 58.2 0.0 1.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCH60873.1 - 0.0052 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MukF_M PF17192.4 CCH60873.1 - 0.0081 15.9 1.8 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 MukF middle domain Kinase-like PF14531.6 CCH60873.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FragX_IP PF05994.11 CCH60873.1 - 0.046 11.8 4.2 0.072 11.1 4.2 1.2 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DUF948 PF06103.11 CCH60873.1 - 0.54 10.5 11.6 1.9 8.8 11.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 CCH60873.1 - 2.5 8.8 8.1 1.8 9.2 0.8 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 CCH60873.1 - 8.6 4.2 10.2 14 3.5 10.2 1.2 1 0 0 1 1 1 0 Prominin GFO_IDH_MocA PF01408.22 CCH60875.1 - 3.4e-09 37.6 0.0 5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCH60875.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Hit1_C PF18268.1 CCH60876.1 - 1.1e-39 134.5 0.1 1.1e-39 134.5 0.1 1.6 2 0 0 2 2 2 1 Hit1 C-terminal zf-HIT PF04438.16 CCH60876.1 - 5.1e-11 42.2 12.9 1.1e-10 41.1 12.9 1.6 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 CCH60876.1 - 0.0094 15.7 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 CCH60876.1 - 0.23 11.6 12.4 0.44 10.7 12.4 1.5 1 0 0 1 1 1 0 MYND finger MMS1_N PF10433.9 CCH60877.1 - 6.5e-74 249.3 7.1 6.5e-74 249.3 7.1 2.0 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CCH60877.1 - 6.5e-49 167.0 2.4 1.2e-48 166.1 0.1 2.7 3 1 0 3 3 3 1 CPSF A subunit region E7 PF00527.18 CCH60877.1 - 0.0071 16.5 1.6 2.7 8.2 0.6 2.6 2 0 0 2 2 2 2 E7 protein, Early protein FAM176 PF14851.6 CCH60877.1 - 0.081 12.6 8.3 0.22 11.2 3.5 2.4 2 0 0 2 2 2 0 FAM176 family GCIP PF13324.6 CCH60877.1 - 0.11 12.1 10.1 1.8 8.1 6.8 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MPP6 PF10175.9 CCH60877.1 - 3.2 8.3 8.5 11 6.5 6.3 2.6 2 0 0 2 2 2 0 M-phase phosphoprotein 6 TLP-20 PF06088.11 CCH60877.1 - 4.5 7.1 11.4 1.1 9.2 2.7 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) KCH PF16944.5 CCH60878.1 - 2.3e-89 299.5 22.7 3.6e-89 298.9 22.7 1.3 1 0 0 1 1 1 1 Fungal potassium channel Sedlin_N PF04628.13 CCH60879.1 - 4.2e-11 43.1 1.1 5.3e-11 42.8 1.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.24 CCH60880.1 - 1.1e-71 242.1 0.0 1.3e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCH60880.1 - 6.3e-11 42.5 0.0 7.2e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH60880.1 - 4e-06 27.0 0.1 1.2e-05 25.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCH60880.1 - 9.1e-06 25.1 0.1 5.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCH60880.1 - 0.00012 21.4 0.3 0.0095 15.2 0.0 2.5 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CCH60880.1 - 0.00041 19.7 0.0 0.094 11.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CCH60880.1 - 0.00082 18.5 0.0 0.15 11.1 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 CCH60880.1 - 0.0039 16.6 0.3 0.013 14.9 0.1 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 CCH60880.1 - 0.0081 15.0 0.1 0.95 8.2 0.0 2.1 2 0 0 2 2 2 2 MCRA family NAD_binding_9 PF13454.6 CCH60880.1 - 0.087 12.8 0.1 0.46 10.5 0.1 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding Beta_elim_lyase PF01212.21 CCH60881.1 - 8.2e-77 258.4 0.0 9.9e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase YL1_C PF08265.11 CCH60882.1 - 8.6e-11 41.4 0.3 8.6e-11 41.4 0.3 2.3 3 0 0 3 3 3 1 YL1 nuclear protein C-terminal domain Minor_capsid_3 PF12691.7 CCH60882.1 - 0.076 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Minor capsid protein from bacteriophage Lzipper-MIP1 PF14389.6 CCH60883.1 - 0.065 13.5 5.0 0.061 13.6 1.0 3.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GDA1_CD39 PF01150.17 CCH60884.1 - 2.9e-126 421.6 0.0 4.6e-126 420.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4020 PF13212.6 CCH60884.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) DUF3446 PF11928.8 CCH60884.1 - 2.8 8.3 10.8 2.7 8.4 6.4 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain NAD_kinase PF01513.21 CCH60885.1 - 1e-87 294.1 0.0 1.3e-87 293.7 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CCH60885.1 - 0.071 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain eIF-1a PF01176.19 CCH60885.1 - 0.11 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 TPALS PF18178.1 CCH60885.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 TIR- and PNP-associating SLOG family Glyco_hydro_16 PF00722.21 CCH60886.1 - 2.1e-44 151.1 4.3 2.1e-44 151.1 4.3 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Macoilin PF09726.9 CCH60886.1 - 0.41 9.2 23.4 0.6 8.6 23.4 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CCH60886.1 - 0.7 8.7 24.9 1 8.1 24.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CCH60886.1 - 0.75 9.6 23.9 1.1 9.1 23.9 1.2 1 0 0 1 1 1 0 SPX domain Lin-8 PF03353.15 CCH60886.1 - 0.8 9.2 5.3 1.3 8.5 5.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cytochrom_C PF00034.21 CCH60887.1 - 6.3e-12 46.5 0.6 9.1e-12 46.0 0.6 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CCH60887.1 - 1.6e-08 34.7 5.1 2.4e-07 31.0 5.1 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Ish1 PF10281.9 CCH60887.1 - 0.054 13.8 0.6 0.97 9.8 0.6 2.3 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Cytochrom_C550 PF14495.6 CCH60887.1 - 0.13 12.0 2.7 0.24 11.1 2.7 1.9 1 1 0 1 1 1 0 Cytochrome c-550 domain Cytochrome_P460 PF16694.5 CCH60887.1 - 0.17 12.3 1.6 9.2 6.6 0.2 2.1 2 0 0 2 2 2 0 Cytochrome P460 Hydrolase PF00702.26 CCH60888.1 - 4e-05 24.0 0.0 0.00025 21.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCH60888.1 - 0.0053 16.9 0.0 0.008 16.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF5639 PF18690.1 CCH60888.1 - 0.096 12.9 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5639) DUF433 PF04255.14 CCH60888.1 - 0.12 12.2 0.1 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF433) NifU_N PF01592.16 CCH60889.1 - 4.4e-54 182.1 0.0 5e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 CCH60889.1 - 0.024 14.8 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 TSCPD domain Flocculin_t3 PF13928.6 CCH60890.1 - 2e-14 53.8 16.2 2e-14 53.8 16.2 3.4 3 0 0 3 3 3 1 Flocculin type 3 repeat BTB_2 PF02214.22 CCH60891.1 - 1.6e-08 34.8 1.9 1.3e-05 25.5 0.1 3.1 2 1 0 2 2 2 2 BTB/POZ domain Uteroglobin PF01099.17 CCH60891.1 - 0.12 12.7 0.9 1.3 9.4 0.2 2.7 2 0 0 2 2 2 0 Uteroglobin family F-box-like PF12937.7 CCH60892.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like RNase_T PF00929.24 CCH60893.1 - 2.3e-05 25.0 0.1 6.7e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CCH60893.1 - 0.012 15.3 1.4 0.041 13.6 0.1 2.5 2 1 0 2 2 2 0 3'-5' exonuclease CHORD PF04968.12 CCH60893.1 - 1 10.1 5.7 1.8 9.3 5.7 1.4 1 0 0 1 1 1 0 CHORD AAA_5 PF07728.14 CCH60894.1 - 1.7e-126 416.8 1.5 4.1e-21 75.4 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CCH60894.1 - 1.2e-52 176.5 0.6 2.1e-19 69.7 0.0 6.4 6 0 0 6 6 5 3 Midasin AAA lid domain AAA_3 PF07726.11 CCH60894.1 - 1.4e-34 118.8 0.0 2.5e-11 43.5 0.0 8.0 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CCH60894.1 - 1.9e-31 108.2 0.0 2.7e-29 101.4 0.0 4.5 4 0 0 4 4 2 1 Midasin AAA lid domain AAA_7 PF12775.7 CCH60894.1 - 2e-30 105.7 6.1 4.2e-06 26.4 0.0 6.9 7 0 0 7 7 6 6 P-loop containing dynein motor region AAA PF00004.29 CCH60894.1 - 2e-26 93.0 2.9 0.0006 20.3 0.0 8.1 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 CCH60894.1 - 1.3e-23 83.6 1.3 0.0018 17.3 0.0 9.2 9 1 0 9 9 8 5 Hydrolytic ATP binding site of dynein motor region Dynein_heavy PF03028.15 CCH60894.1 - 7e-22 77.7 0.0 8.4e-06 25.9 0.0 8.4 8 1 0 8 8 7 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CCH60894.1 - 1.9e-21 76.5 0.1 0.0011 18.7 0.1 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_16 PF13191.6 CCH60894.1 - 3.1e-21 76.5 8.2 0.0051 17.2 0.6 8.7 7 2 0 7 7 6 5 AAA ATPase domain AAA_30 PF13604.6 CCH60894.1 - 2.2e-18 66.7 0.0 0.092 12.5 0.0 7.6 7 1 0 7 7 7 4 AAA domain TsaE PF02367.17 CCH60894.1 - 8.4e-18 64.6 3.5 0.077 13.0 0.0 7.0 6 0 0 6 6 6 5 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CCH60894.1 - 1.5e-17 64.0 0.2 0.0029 17.7 0.0 6.6 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_14 PF13173.6 CCH60894.1 - 6.4e-16 58.6 0.6 0.0049 16.9 0.0 8.6 7 0 0 7 7 7 2 AAA domain AAA_22 PF13401.6 CCH60894.1 - 1.4e-15 57.7 2.7 0.13 12.5 0.0 7.7 7 0 0 7 7 6 3 AAA domain T2SSE PF00437.20 CCH60894.1 - 1e-14 54.3 6.1 0.031 13.3 0.4 6.3 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_33 PF13671.6 CCH60894.1 - 2.9e-13 50.2 0.7 0.0018 18.4 0.1 6.7 6 0 0 6 6 6 1 AAA domain ABC_tran PF00005.27 CCH60894.1 - 1e-12 48.7 27.6 0.00059 20.4 0.2 8.5 7 1 1 8 8 6 4 ABC transporter RNA_helicase PF00910.22 CCH60894.1 - 9.8e-12 45.2 3.2 1.7 9.1 0.0 7.5 7 0 0 7 7 6 2 RNA helicase RsgA_GTPase PF03193.16 CCH60894.1 - 2.5e-11 43.8 10.2 0.15 12.0 0.0 6.6 6 0 0 6 6 6 3 RsgA GTPase IstB_IS21 PF01695.17 CCH60894.1 - 1.2e-10 41.4 0.1 0.97 9.1 0.0 6.4 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_19 PF13245.6 CCH60894.1 - 2.4e-10 40.9 5.3 0.51 10.7 0.1 7.1 7 0 0 7 7 6 2 AAA domain Zeta_toxin PF06414.12 CCH60894.1 - 4.2e-10 39.2 2.2 1.7 7.9 0.0 7.7 8 0 0 8 8 8 2 Zeta toxin Mg_chelatase PF01078.21 CCH60894.1 - 6.8e-10 38.7 5.5 3.5 6.9 0.0 8.6 9 1 1 10 10 9 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCH60894.1 - 9.4e-10 39.1 34.8 0.025 15.1 0.0 9.5 9 0 0 9 9 6 4 AAA domain PduV-EutP PF10662.9 CCH60894.1 - 1.2e-09 38.1 2.5 0.046 13.5 0.0 6.3 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 CCH60894.1 - 1e-08 35.3 10.0 0.52 10.2 0.0 7.2 7 0 0 7 7 6 2 Rad17 P-loop domain RuvB_N PF05496.12 CCH60894.1 - 1.6e-08 34.5 4.0 0.21 11.3 0.0 6.3 8 0 0 8 8 6 2 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 CCH60894.1 - 2.5e-08 33.5 4.0 1.7 8.5 0.0 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CCH60894.1 - 2.4e-07 30.5 5.6 0.082 12.5 0.0 5.7 6 0 0 6 6 5 1 AAA domain NACHT PF05729.12 CCH60894.1 - 4.6e-07 29.9 10.6 0.31 10.9 0.0 6.6 7 0 0 7 7 6 1 NACHT domain TniB PF05621.11 CCH60894.1 - 1.2e-06 28.1 1.1 1.3 8.4 0.0 5.9 6 0 0 6 6 6 1 Bacterial TniB protein SRP54 PF00448.22 CCH60894.1 - 1.9e-06 27.6 5.5 1.1 8.9 0.1 6.0 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CCH60894.1 - 2.6e-06 27.8 11.0 2.7 8.2 0.1 6.7 6 0 0 6 6 6 2 AAA domain MMR_HSR1 PF01926.23 CCH60894.1 - 2.7e-06 27.4 2.3 10 6.3 0.0 5.9 5 0 0 5 5 5 0 50S ribosome-binding GTPase PhoH PF02562.16 CCH60894.1 - 9e-06 25.3 1.4 6.1 6.2 0.0 5.4 5 0 0 5 5 5 0 PhoH-like protein Roc PF08477.13 CCH60894.1 - 2.9e-05 24.3 7.6 8 6.7 0.1 6.5 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase Bac_DnaA PF00308.18 CCH60894.1 - 3.7e-05 23.7 0.4 5.9 6.7 0.0 5.1 5 0 0 5 5 4 0 Bacterial dnaA protein AAA_8 PF12780.7 CCH60894.1 - 0.00048 19.5 2.0 3.6 6.9 0.0 5.9 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 ATP-synt_ab PF00006.25 CCH60894.1 - 0.00056 19.6 1.0 4.8 6.8 0.1 4.1 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.18 CCH60894.1 - 0.0012 18.7 5.1 0.7 9.6 0.0 5.9 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CCH60894.1 - 0.0018 18.2 11.9 3.1 7.7 0.4 5.6 6 0 0 6 6 5 1 NTPase ATPase PF06745.13 CCH60894.1 - 0.004 16.5 1.1 9 5.6 0.0 4.4 4 0 0 4 4 4 0 KaiC AAA_23 PF13476.6 CCH60894.1 - 0.0077 16.7 0.1 0.0077 16.7 0.1 11.6 10 1 2 12 12 5 2 AAA domain CPT PF07931.12 CCH60894.1 - 0.037 13.9 3.5 19 5.0 0.0 5.2 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.18 CCH60894.1 - 0.18 11.1 0.8 27 4.0 0.0 4.1 4 0 0 4 4 4 0 FtsK/SpoIIIE family tRNA_int_endo PF01974.17 CCH60895.1 - 3.7e-25 87.8 0.1 7.2e-25 86.9 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DivIC PF04977.15 CCH60895.1 - 0.099 12.4 6.3 0.2 11.5 6.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4140 PF13600.6 CCH60895.1 - 0.18 12.2 1.8 0.36 11.3 1.8 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Fmp27_WPPW PF10359.9 CCH60895.1 - 0.31 9.8 5.7 0.42 9.4 5.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CDC45 PF02724.14 CCH60896.1 - 2.3e-209 696.9 1.5 2.6e-209 696.7 1.5 1.0 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.7 CCH60896.1 - 5.3 6.8 13.9 2.2 8.1 8.3 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein ANAPC9 PF12856.7 CCH60897.1 - 2.9e-09 37.1 0.4 5.9e-09 36.1 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 9 DUF1651 PF07864.11 CCH60897.1 - 0.13 12.6 0.2 0.42 11.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1651) adh_short PF00106.25 CCH60898.1 - 2.3e-11 43.5 0.0 1.9e-10 40.5 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH60898.1 - 0.0021 17.7 0.5 0.037 13.6 0.0 2.7 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase PhoU_div PF01865.16 CCH60898.1 - 0.0098 15.2 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF47 Zn_ribbon_17 PF17120.5 CCH60899.1 - 2.6e-17 62.2 13.9 4.6e-17 61.4 13.9 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCH60899.1 - 1.8e-05 25.4 21.2 0.0091 16.8 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 CCH60899.1 - 0.00047 20.4 2.7 0.00048 20.4 0.1 2.4 2 1 1 3 3 3 1 RWD domain zf-rbx1 PF12678.7 CCH60899.1 - 0.0029 17.9 8.6 0.0064 16.7 8.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCH60899.1 - 0.12 12.7 9.9 0.28 11.5 9.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-ANAPC11 PF12861.7 CCH60899.1 - 0.22 11.6 9.6 0.5 10.4 9.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-ribbon_3 PF13248.6 CCH60899.1 - 0.9 9.0 6.5 0.33 10.4 3.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_16 PF17034.5 CCH60899.1 - 4.1 7.6 12.2 2.4 8.4 8.6 2.7 2 0 0 2 2 2 0 Zinc-ribbon like family EPSP_synthase PF00275.20 CCH60900.1 - 7e-142 473.0 0.0 1e-141 472.4 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CCH60900.1 - 1.1e-101 339.4 0.0 1.8e-101 338.7 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CCH60900.1 - 1e-56 192.8 0.0 2.1e-56 191.8 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CCH60900.1 - 9.3e-38 129.8 0.1 1.2e-35 123.0 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CCH60900.1 - 2.1e-21 76.0 0.0 9.7e-21 73.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CCH60900.1 - 2.1e-08 33.8 0.2 4.6e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CCH60900.1 - 2.9e-07 30.6 0.0 1.3e-06 28.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 CCH60900.1 - 1.1e-06 28.6 0.0 2.3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 CCH60900.1 - 0.012 15.8 0.0 0.046 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sacchrp_dh_NADP PF03435.18 CCH60900.1 - 0.067 13.4 0.0 0.25 11.6 0.0 2.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 CCH60900.1 - 0.11 11.8 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 ThiF family THF_DHG_CYH PF00763.23 CCH60900.1 - 0.13 12.6 0.0 0.44 10.8 0.0 1.9 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DHHC PF01529.20 CCH60901.1 - 2.9e-27 95.4 8.3 2.9e-27 95.4 8.3 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase Fungal_trans PF04082.18 CCH60902.1 - 4.9e-40 137.2 1.1 9.1e-40 136.4 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH60902.1 - 0.013 15.6 1.1 0.022 14.9 1.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain L31 PF09784.9 CCH60902.1 - 0.033 14.6 0.1 0.077 13.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF2841 PF11001.8 CCH60903.1 - 1.1e-35 122.3 1.6 2.2e-35 121.4 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2284 PF10050.9 CCH60903.1 - 0.001 18.8 0.1 0.0022 17.8 0.1 1.5 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) Chordopox_A30L PF06015.12 CCH60903.1 - 0.04 13.8 0.5 2.3 8.1 0.1 3.0 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Cyclin PF08613.11 CCH60904.1 - 6.8e-42 143.6 1.7 1.3e-26 93.9 0.2 4.3 5 1 0 5 5 5 2 Cyclin PET117 PF15786.5 CCH60905.1 - 7.8e-29 99.7 3.9 3.6e-28 97.6 3.9 1.8 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Ribonuc_L-PSP PF01042.21 CCH60906.1 - 1.7e-38 131.3 0.8 2.1e-38 131.0 0.8 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Transp_cyt_pur PF02133.15 CCH60907.1 - 8.4e-88 295.1 37.0 1e-87 294.8 37.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PhoLip_ATPase_C PF16212.5 CCH60908.1 - 5.5e-46 157.3 18.3 5.5e-46 157.3 18.3 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCH60908.1 - 1.2e-17 63.3 4.2 4.7e-17 61.4 4.2 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCH60908.1 - 1.5e-13 50.6 0.0 3.4e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH60908.1 - 3.4e-11 43.8 0.7 7.4e-06 26.4 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH60908.1 - 9.7e-09 35.2 0.0 7.8e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Nab2 PF11517.8 CCH60908.1 - 0.0088 16.3 0.2 4.5 7.6 0.1 2.7 2 0 0 2 2 2 2 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Hydrolase_3 PF08282.12 CCH60908.1 - 0.017 14.9 0.0 0.017 14.9 0.0 3.5 4 1 1 5 5 5 0 haloacid dehalogenase-like hydrolase EXS PF03124.14 CCH60909.1 - 7.3e-80 268.8 27.1 1.1e-79 268.2 27.1 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CCH60909.1 - 4.5e-17 63.0 11.7 7.5e-14 52.4 1.5 2.8 3 0 0 3 3 3 2 SPX domain DUF685 PF05085.12 CCH60909.1 - 0.15 11.3 1.7 0.38 10.0 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF685) WD40 PF00400.32 CCH60910.1 - 8.4e-34 115.1 29.3 1e-05 26.1 0.7 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 CCH60910.1 - 5.4e-13 48.6 1.9 1.1e-12 47.6 1.9 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CCH60910.1 - 6.3e-12 44.9 1.5 0.013 14.2 0.1 4.6 3 2 2 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.33 CCH60910.1 - 2.3e-09 36.9 1.6 4.9e-09 35.8 1.6 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CCH60910.1 - 6.2e-07 29.6 0.1 0.5 10.7 0.0 5.3 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCH60910.1 - 0.00083 18.8 0.6 0.2 10.9 0.1 2.9 2 1 1 3 3 3 2 WD40-like domain zf-MYND PF01753.18 CCH60910.1 - 0.025 14.6 1.1 0.11 12.6 1.1 2.1 1 0 0 1 1 1 0 MYND finger F-box_4 PF15966.5 CCH60910.1 - 0.028 14.3 0.0 0.081 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box BBS2_Mid PF14783.6 CCH60910.1 - 0.11 12.5 0.0 7.2 6.7 0.0 3.3 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region CBM_21 PF03370.13 CCH60911.1 - 2.5e-14 53.4 0.0 5.2e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCH60911.1 - 0.00063 20.3 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Putative_PNPOx PF01243.20 CCH60911.1 - 0.019 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Mito_carr PF00153.27 CCH60913.1 - 6.3e-46 154.2 6.1 2.5e-16 59.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ArfGap PF01412.18 CCH60914.1 - 4e-35 120.4 0.9 4e-35 120.4 0.9 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf AA_kinase PF00696.28 CCH60915.1 - 2.6e-41 141.8 0.0 6.9e-41 140.4 0.0 1.7 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CCH60915.1 - 1.7e-10 40.4 0.5 0.00031 20.4 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CCH60915.1 - 5.5e-08 32.5 2.5 1.3e-05 24.9 0.5 2.7 2 0 0 2 2 2 2 ACT domain NAD_binding_1 PF00175.21 CCH60916.1 - 3.1e-30 105.0 0.0 4.7e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CCH60916.1 - 3.4e-28 97.9 0.0 5.6e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CCH60916.1 - 0.00017 21.8 0.0 0.085 13.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CCH60916.1 - 0.0065 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain BAR_2 PF10455.9 CCH60917.1 - 4e-64 216.5 4.2 8.3e-64 215.5 4.2 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCH60917.1 - 9.8e-15 54.8 8.2 3.8e-14 52.9 6.7 2.3 1 1 1 2 2 2 1 BAR domain BAR_3 PF16746.5 CCH60917.1 - 0.0055 16.4 1.7 0.0055 16.4 1.7 2.1 2 1 0 2 2 2 1 BAR domain of APPL family P_C10 PF14974.6 CCH60917.1 - 0.24 11.5 2.9 0.25 11.4 0.3 2.3 3 0 0 3 3 3 0 Protein C10 Lectin_N PF03954.14 CCH60917.1 - 0.36 10.6 4.6 1 9.1 0.4 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 CCH60917.1 - 5.8 7.1 15.4 0.81 9.9 1.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ofd1_CTDD PF10637.9 CCH60918.1 - 1.8e-76 256.9 6.3 4.2e-74 249.1 4.4 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CCH60918.1 - 2.7e-25 88.9 0.0 6e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CCH60918.1 - 6e-15 55.9 0.0 2.1e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CCH60918.1 - 0.032 14.7 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily PdxA PF04166.12 CCH60918.1 - 0.25 10.7 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Complex1_LYR PF05347.15 CCH60919.1 - 9.1e-20 70.5 0.9 1.1e-19 70.2 0.9 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCH60919.1 - 5.2e-05 23.9 0.7 5.8e-05 23.8 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CCH60919.1 - 0.0053 17.3 0.0 0.0058 17.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like MIF4G PF02854.19 CCH60919.1 - 0.013 15.1 0.2 0.014 15.0 0.2 1.2 1 0 0 1 1 1 0 MIF4G domain Apq12 PF12716.7 CCH60920.1 - 0.032 14.2 10.4 0.032 14.2 10.4 2.0 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis DnaJ-X PF14308.6 CCH60921.1 - 1e-59 201.5 10.0 1e-59 201.5 10.0 2.0 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCH60921.1 - 1.2e-25 89.4 1.1 1.2e-25 89.4 1.1 2.6 3 0 0 3 3 3 1 DnaJ domain TipAS PF07739.13 CCH60921.1 - 0.3 11.6 4.1 0.43 11.1 0.5 2.9 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Ribosomal_L17 PF01196.19 CCH60921.1 - 3.8 8.5 6.1 1.2 10.1 2.2 2.2 2 1 0 2 2 2 0 Ribosomal protein L17 Metallophos PF00149.28 CCH60922.1 - 2.1e-06 28.4 9.8 8e-06 26.5 9.8 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.29 CCH60923.1 - 3.4e-39 134.3 0.0 7e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CCH60923.1 - 3.9e-09 36.4 0.1 1.7e-08 34.3 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 CCH60923.1 - 1.2e-07 32.0 0.1 0.00042 20.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 CCH60923.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CCH60923.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCH60923.1 - 0.00017 21.9 0.6 0.0066 16.7 0.6 2.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCH60923.1 - 0.00066 19.7 0.0 0.042 13.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CCH60923.1 - 0.00071 18.9 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 CCH60923.1 - 0.0033 17.4 0.1 0.018 15.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CCH60923.1 - 0.0039 16.8 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCH60923.1 - 0.0086 16.5 0.1 0.026 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCH60923.1 - 0.0092 16.1 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH60923.1 - 0.017 15.7 0.0 0.1 13.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CCH60923.1 - 0.02 14.3 2.0 0.025 14.0 0.2 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCH60923.1 - 0.022 14.5 0.9 0.35 10.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CCH60923.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CCH60923.1 - 0.088 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Fimbrial_CS1 PF04449.12 CCH60923.1 - 0.14 12.3 2.6 7.5 6.7 0.5 3.4 3 0 0 3 3 3 0 CS1 type fimbrial major subunit Not3 PF04065.15 CCH60924.1 - 4.8e-80 268.3 28.6 4.8e-80 268.3 28.6 2.7 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCH60924.1 - 8.4e-21 74.4 0.3 3.6e-20 72.4 0.3 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CCH60924.1 - 0.0079 16.5 2.2 0.0079 16.5 2.2 4.4 4 0 0 4 4 4 1 Syntaxin-like protein DUF3377 PF11857.8 CCH60925.1 - 2.2 8.3 5.1 1.8 8.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Septin PF00735.18 CCH60927.1 - 1.8e-105 352.3 0.4 2.1e-105 352.0 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCH60927.1 - 3.6e-09 36.7 0.2 7.1e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH60927.1 - 5.1e-07 29.7 1.0 8.4e-07 29.0 0.3 1.7 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CCH60927.1 - 3.8e-06 26.6 0.5 0.00031 20.3 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CCH60927.1 - 5.1e-06 26.0 0.5 1.1e-05 24.9 0.5 1.7 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CCH60927.1 - 5e-05 23.4 1.6 0.11 12.5 0.8 2.4 1 1 1 2 2 2 2 Dynamin family NB-ARC PF00931.22 CCH60927.1 - 0.00024 20.4 0.1 0.00047 19.4 0.1 1.4 1 1 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 CCH60927.1 - 0.001 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.6 CCH60927.1 - 0.0031 17.3 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH60927.1 - 0.0055 17.1 0.1 0.0096 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 CCH60927.1 - 0.0064 17.0 1.1 0.014 15.9 1.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CCH60927.1 - 0.0097 16.2 0.1 0.022 15.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCH60927.1 - 0.022 14.8 0.0 0.063 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 CCH60927.1 - 0.023 13.7 0.3 0.043 12.9 0.2 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 CCH60927.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CCH60927.1 - 0.032 14.0 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCH60927.1 - 0.045 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CCH60927.1 - 0.048 13.8 0.7 0.35 11.0 0.3 2.5 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CCH60927.1 - 0.09 12.3 0.3 3 7.4 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF815 PF05673.13 CCH60927.1 - 0.091 11.9 0.1 0.14 11.3 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CCH60927.1 - 0.12 12.1 0.1 1.4 8.7 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 CCH60927.1 - 0.13 12.7 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Citrate_synt PF00285.21 CCH60928.1 - 2.8e-100 335.9 0.0 3.6e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SRI PF08236.11 CCH60928.1 - 0.041 14.1 2.7 0.78 9.9 0.4 2.7 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain BAR PF03114.18 CCH60929.1 - 2.8e-54 184.3 3.8 3.3e-54 184.1 3.8 1.0 1 0 0 1 1 1 1 BAR domain Sigma70_ner PF04546.13 CCH60929.1 - 0.025 14.4 1.0 0.05 13.5 1.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region MgtE_N PF03448.17 CCH60929.1 - 0.026 15.1 0.4 0.23 12.1 0.0 2.6 3 0 0 3 3 3 0 MgtE intracellular N domain DUF5339 PF17274.2 CCH60929.1 - 0.028 15.3 1.6 0.12 13.2 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) DUF2303 PF10065.9 CCH60929.1 - 0.036 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Jnk-SapK_ap_N PF09744.9 CCH60929.1 - 0.26 11.5 3.8 0.48 10.6 0.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4164 PF13747.6 CCH60929.1 - 0.35 11.2 2.4 0.5 10.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) BRE1 PF08647.11 CCH60929.1 - 1.1 9.4 7.2 14 5.8 2.4 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 CCH60929.1 - 3.1 8.0 7.9 7.1 6.8 0.2 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Gpr1_Fun34_YaaH PF01184.19 CCH60930.1 - 3.2e-92 307.8 15.6 3.8e-92 307.6 15.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ABC2_membrane PF01061.24 CCH60931.1 - 8.2e-38 129.9 22.2 1.8e-37 128.9 22.2 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CCH60931.1 - 7.5e-30 104.2 0.0 1.6e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCH60931.1 - 0.00013 21.9 3.5 0.092 12.5 0.6 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CCH60931.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CCH60931.1 - 0.0075 16.0 0.3 0.026 14.3 0.3 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain EGF_2 PF07974.13 CCH60931.1 - 0.017 15.5 7.1 0.017 15.5 7.1 3.8 3 0 0 3 3 3 0 EGF-like domain AAA_25 PF13481.6 CCH60931.1 - 0.063 12.8 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CCH60931.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCH60931.1 - 0.094 12.6 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 NACHT domain ABC_ATPase PF09818.9 CCH60931.1 - 0.13 11.1 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_16 PF13191.6 CCH60931.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain PGK PF00162.19 CCH60932.1 - 3.8e-149 496.7 0.5 4.3e-149 496.6 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase F420_ligase PF01996.16 CCH60932.1 - 0.054 12.8 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 0 F420-0:Gamma-glutamyl ligase DNA_pol_B_thumb PF14791.6 CCH60933.1 - 7.3e-16 58.1 0.0 1.8e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CCH60933.1 - 1.5e-15 57.3 0.0 1.6e-14 54.1 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.6 CCH60933.1 - 2.4e-13 50.3 0.3 1e-12 48.2 0.4 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CCH60933.1 - 5.7e-09 35.7 0.0 1.9e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 CCH60933.1 - 0.017 15.5 0.9 0.32 11.4 0.2 3.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCH60933.1 - 0.079 13.4 0.1 0.24 11.8 0.1 1.9 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LPD7 PF18821.1 CCH60933.1 - 0.18 11.9 0.0 0.54 10.4 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 HAD PF12710.7 CCH60934.1 - 1.9e-19 70.8 0.0 2.4e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CCH60934.1 - 4.7e-07 29.5 0.1 6.2e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 CCH60934.1 - 2.7e-06 27.1 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 CCH60934.1 - 0.00041 20.7 0.0 0.02 15.2 0.0 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2683 PF10884.8 CCH60934.1 - 0.032 14.5 0.0 0.92 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) EF-hand_7 PF13499.6 CCH60935.1 - 9.5e-05 22.8 1.4 9.5e-05 22.8 1.4 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CCH60935.1 - 0.0089 15.9 2.7 1.2 9.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain WWE PF02825.20 CCH60935.1 - 0.13 12.9 0.6 0.85 10.3 0.0 2.2 2 0 0 2 2 2 0 WWE domain PLA2_B PF01735.18 CCH60936.1 - 8.5e-78 261.9 24.0 9.2e-35 120.0 4.2 3.3 2 2 0 3 3 3 3 Lysophospholipase catalytic domain Patatin PF01734.22 CCH60936.1 - 7.5e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 CCH60937.1 - 2e-43 148.2 0.2 8.8e-22 78.1 0.0 4.5 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 CCH60937.1 - 1.9e-29 101.5 0.4 1.1e-28 99.0 0.0 2.5 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 CCH60937.1 - 1.7e-17 64.2 0.4 0.0089 15.9 0.0 5.0 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH60937.1 - 4.3e-14 52.5 0.1 2.9e-05 23.6 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCH60937.1 - 1.5e-09 38.7 3.7 0.00046 20.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CCH60937.1 - 1.5e-08 34.7 0.1 0.00017 21.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CCH60937.1 - 2.1e-08 33.8 0.0 0.007 16.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH60937.1 - 7.7e-08 32.7 0.1 0.0059 16.9 0.0 3.9 4 1 0 4 4 3 2 AAA domain AAA_28 PF13521.6 CCH60937.1 - 4.5e-07 30.3 0.1 0.016 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CCH60937.1 - 5.7e-07 29.6 0.0 0.0024 17.9 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCH60937.1 - 1.2e-06 28.7 0.0 1.7e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Dynamin family HEAT_2 PF13646.6 CCH60937.1 - 2.1e-06 28.0 0.9 0.0049 17.2 0.1 2.9 1 1 1 2 2 2 2 HEAT repeats AAA PF00004.29 CCH60937.1 - 3.4e-06 27.5 0.3 0.38 11.2 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MMS19_C PF12460.8 CCH60937.1 - 8e-06 25.2 2.8 0.0043 16.2 0.2 3.2 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CCH60937.1 - 1.5e-05 25.3 3.2 0.48 11.0 0.1 4.4 5 0 0 5 5 3 2 HEAT-like repeat RNA_helicase PF00910.22 CCH60937.1 - 2.9e-05 24.4 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CCH60937.1 - 7.5e-05 22.9 0.0 0.57 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CCH60937.1 - 0.0001 22.9 0.1 0.77 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCH60937.1 - 0.00019 21.9 0.2 0.32 11.4 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain MeaB PF03308.16 CCH60937.1 - 0.00019 20.5 0.1 0.53 9.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_27 PF13514.6 CCH60937.1 - 0.00036 20.2 0.0 0.35 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain CLASP_N PF12348.8 CCH60937.1 - 0.00041 20.0 0.8 0.63 9.6 0.1 2.6 1 1 1 2 2 2 2 CLASP N terminal Rad17 PF03215.15 CCH60937.1 - 0.0013 18.7 0.0 0.6 10.0 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain ParcG PF10274.9 CCH60937.1 - 0.0018 18.4 0.9 4.6 7.3 0.0 3.1 2 1 1 3 3 3 0 Parkin co-regulated protein AAA_24 PF13479.6 CCH60937.1 - 0.0019 18.0 0.0 1.4 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain Vac14_Fab1_bd PF12755.7 CCH60937.1 - 0.0025 18.4 0.4 0.44 11.2 0.0 3.4 3 1 1 5 5 2 1 Vacuolar 14 Fab1-binding region AAA_30 PF13604.6 CCH60937.1 - 0.0028 17.4 0.2 3 7.5 0.0 3.2 4 0 0 4 4 2 1 AAA domain SbcCD_C PF13558.6 CCH60937.1 - 0.0032 17.7 0.1 1.7 9.0 0.0 3.6 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 CCH60937.1 - 0.0039 16.9 0.0 0.29 10.9 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation HEAT PF02985.22 CCH60937.1 - 0.0043 17.2 0.5 3.5 8.1 0.0 4.2 4 0 0 4 4 2 0 HEAT repeat NACHT PF05729.12 CCH60937.1 - 0.011 15.7 0.0 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 CCH60937.1 - 0.013 15.1 0.1 7.8 6.0 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 CCH60937.1 - 0.015 15.0 0.0 6.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_14 PF13173.6 CCH60937.1 - 0.02 14.9 0.0 8.6 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 CCH60937.1 - 0.021 15.0 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 CCH60937.1 - 0.025 14.3 0.1 21 4.8 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 CCH60937.1 - 0.026 14.1 0.0 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CCH60937.1 - 0.026 14.4 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 CCH60937.1 - 0.027 13.5 0.1 0.22 10.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 CCH60937.1 - 0.03 14.0 7.0 0.32 10.6 0.0 3.5 4 0 0 4 4 2 0 AAA ATPase domain MutS_V PF00488.21 CCH60937.1 - 0.031 14.3 0.1 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 MutS domain V ATP_bind_1 PF03029.17 CCH60937.1 - 0.042 13.6 0.2 8.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CCH60937.1 - 0.043 13.6 0.2 4.7 7.0 0.0 3.1 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 CCH60937.1 - 0.055 13.4 0.6 12 5.8 0.0 3.0 3 1 0 3 3 2 0 ATPase domain predominantly from Archaea UME PF08064.13 CCH60937.1 - 0.055 13.4 1.0 0.54 10.2 0.4 2.6 1 1 0 2 2 2 0 UME (NUC010) domain G-alpha PF00503.20 CCH60937.1 - 0.067 12.3 0.0 6.2 5.9 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit Ploopntkinase3 PF18751.1 CCH60937.1 - 0.069 13.1 0.0 13 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF87 PF01935.17 CCH60937.1 - 0.069 13.2 5.3 0.43 10.6 0.0 3.9 4 0 0 4 4 3 0 Helicase HerA, central domain Septin PF00735.18 CCH60937.1 - 0.078 12.2 0.3 2.6 7.3 0.0 2.7 3 0 0 3 3 2 0 Septin Adeno_IVa2 PF02456.15 CCH60937.1 - 0.082 11.7 0.0 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NUC173 PF08161.12 CCH60937.1 - 0.084 12.5 0.8 0.75 9.4 0.8 2.2 1 1 1 2 2 2 0 NUC173 domain Mg_chelatase PF01078.21 CCH60937.1 - 0.087 12.2 0.0 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CCH60937.1 - 0.11 12.5 0.1 11 6.0 0.1 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MukB PF04310.12 CCH60937.1 - 0.12 12.1 0.3 15 5.3 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal RE_HindVP PF09519.10 CCH60937.1 - 0.16 11.0 0.4 0.26 10.3 0.4 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease Adaptin_N PF01602.20 CCH60937.1 - 0.16 10.5 6.5 0.38 9.3 1.4 2.4 1 1 1 3 3 3 0 Adaptin N terminal region DUF3437 PF11919.8 CCH60937.1 - 1.1 9.2 3.8 6 6.9 0.2 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF3437) AAA_13 PF13166.6 CCH60937.1 - 1.5 7.3 9.4 5.6 5.5 0.0 3.9 4 1 0 4 4 4 0 AAA domain Pkinase PF00069.25 CCH60938.1 - 6.1e-60 202.8 0.0 3.5e-59 200.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60938.1 - 6.9e-26 91.1 0.0 1.9e-24 86.4 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH60938.1 - 6.4e-07 29.0 0.0 0.0061 15.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CCH60938.1 - 0.0025 17.2 0.0 0.0065 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.26 CCH60939.1 - 2.9e-45 154.1 0.0 3.4e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Uteroglobin PF01099.17 CCH60939.1 - 0.076 13.4 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family HA2 PF04408.23 CCH60940.1 - 1.1e-21 77.1 0.0 1.1e-21 77.1 0.0 2.2 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCH60940.1 - 1.7e-18 66.7 0.0 4.4e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCH60940.1 - 4.9e-14 52.6 0.0 2.5e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCH60940.1 - 7.8e-08 32.3 0.3 2e-07 30.9 0.3 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH60940.1 - 7.9e-06 26.2 0.1 2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CCH60940.1 - 0.00074 18.7 0.3 0.0042 16.2 0.1 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 CCH60940.1 - 0.0013 18.5 0.1 0.0048 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCH60940.1 - 0.0017 18.8 6.8 0.037 14.6 0.7 3.3 2 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.6 CCH60940.1 - 0.0049 16.9 0.5 0.13 12.3 0.5 3.0 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 CCH60940.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.9 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 CCH60940.1 - 0.013 15.1 0.3 0.046 13.3 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CCH60940.1 - 0.021 15.2 0.1 0.041 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCH60940.1 - 0.023 14.2 0.1 0.075 12.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 CCH60940.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 CCH60940.1 - 0.039 13.1 0.1 0.094 11.9 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain Amino_oxidase PF01593.24 CCH60941.1 - 1.1e-14 54.6 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCH60941.1 - 1.5e-12 47.5 0.0 3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCH60941.1 - 7e-06 26.5 0.0 0.0059 17.1 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CCH60941.1 - 3.3e-05 23.3 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCH60941.1 - 0.00041 19.7 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 CCH60941.1 - 0.0019 16.8 0.0 0.0086 14.7 0.0 1.9 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) DAO PF01266.24 CCH60941.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CCH60941.1 - 0.038 14.0 0.0 0.096 12.7 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding RRM_1 PF00076.22 CCH60942.1 - 1.6e-08 34.3 0.0 3.9e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCH60942.1 - 0.013 15.1 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CCH60942.1 - 0.037 14.1 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 Limkain b1 AMP-binding PF00501.28 CCH60943.1 - 2.2e-66 224.2 0.0 3.5e-66 223.5 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme DUF2104 PF09877.9 CCH60943.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) EB1 PF03271.17 CCH60944.1 - 9.1e-12 45.0 0.1 2.2e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CCH60944.1 - 5.2e-05 23.4 1.3 7.2e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain TolA_bind_tri PF16331.5 CCH60944.1 - 0.00045 20.2 0.5 0.00095 19.2 0.5 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation FlxA PF14282.6 CCH60944.1 - 0.0012 18.8 5.1 0.0039 17.2 5.1 1.9 1 0 0 1 1 1 1 FlxA-like protein Phage_GP20 PF06810.11 CCH60944.1 - 0.023 14.5 1.9 0.05 13.4 1.9 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3450 PF11932.8 CCH60944.1 - 0.036 13.4 1.3 0.058 12.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 CCH60944.1 - 0.042 14.2 1.6 0.096 13.1 1.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CCH60944.1 - 0.074 12.8 1.4 0.15 11.9 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5320 PF17253.2 CCH60944.1 - 0.12 13.4 0.2 0.29 12.2 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5320) ERM PF00769.19 CCH60944.1 - 0.34 10.7 8.7 0.045 13.6 4.5 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4124 PF13511.6 CCH60944.1 - 0.93 9.9 2.5 0.55 10.6 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Cep57_CLD PF14073.6 CCH60944.1 - 1.2 9.1 6.3 0.073 13.1 0.7 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Peptidase_M41 PF01434.18 CCH60945.1 - 1.3e-65 220.8 0.0 2.2e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CCH60945.1 - 4.1e-43 147.0 0.1 1.3e-42 145.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 CCH60945.1 - 2e-10 41.0 4.0 7.1e-10 39.2 4.0 2.0 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 CCH60945.1 - 2.3e-10 40.1 0.0 5.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 CCH60945.1 - 0.00065 19.0 0.9 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CCH60945.1 - 0.00083 19.6 1.7 0.12 12.6 0.3 3.3 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 CCH60945.1 - 0.0012 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCH60945.1 - 0.0055 17.1 0.1 0.024 15.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CCH60945.1 - 0.0086 16.1 0.1 0.036 14.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CCH60945.1 - 0.01 15.5 0.0 0.041 13.6 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 CCH60945.1 - 0.011 16.1 0.5 0.024 15.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 CCH60945.1 - 0.033 14.3 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 CCH60945.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCH60945.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CCH60945.1 - 0.078 12.3 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CCH60945.1 - 0.084 12.9 0.0 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CCH60945.1 - 0.23 12.0 2.5 0.46 11.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.25 CCH60946.1 - 6.5e-116 385.4 0.0 9.3e-116 384.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CCH60946.1 - 2.5e-44 150.0 0.0 4.7e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CCH60946.1 - 2.5e-17 63.1 2.2 5.4e-17 62.1 2.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Occludin_ELL PF07303.13 CCH60946.1 - 0.23 12.2 0.7 2.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Occludin homology domain MIS13 PF08202.11 CCH60947.1 - 9.7e-12 44.8 20.7 2.1e-09 37.1 18.1 3.0 3 1 0 3 3 3 2 Mis12-Mtw1 protein family Sedlin_N PF04628.13 CCH60948.1 - 4.3e-35 120.7 0.0 1e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CCH60948.1 - 7.4e-06 25.9 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family RVT_2 PF07727.14 CCH60949.1 - 9.8e-29 100.7 0.0 1.4e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4595 PF15283.6 CCH60949.1 - 0.011 15.9 3.3 0.017 15.2 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4595) with porin-like fold PB1 PF00564.24 CCH60949.1 - 0.11 12.5 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 PB1 domain Cut8 PF08559.10 CCH60951.1 - 2.1e-57 194.5 21.7 2.1e-57 194.5 21.7 1.5 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein SUIM_assoc PF16619.5 CCH60951.1 - 0.0049 16.9 4.6 0.0049 16.9 4.6 2.3 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 FHIPEP PF00771.20 CCH60951.1 - 0.02 13.4 2.6 0.26 9.7 2.1 2.1 2 0 0 2 2 2 0 FHIPEP family Phostensin_N PF13916.6 CCH60951.1 - 0.62 10.4 4.1 1.2 9.5 4.1 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal TFIIA PF03153.13 CCH60951.1 - 1.6 8.6 14.6 2.4 8.1 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 CCH60952.1 - 5e-12 46.0 0.1 5.5e-08 33.0 0.0 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH60952.1 - 3.5e-05 24.5 11.5 0.17 12.8 0.5 5.5 6 1 0 6 6 6 2 WD domain, G-beta repeat Lum_binding PF00677.17 CCH60953.1 - 5.2e-44 148.1 4.3 7.2e-23 80.4 0.9 2.2 2 0 0 2 2 2 2 Lumazine binding domain Asp PF00026.23 CCH60954.1 - 5.9e-48 163.9 4.3 7.3e-48 163.6 4.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH60954.1 - 5.7e-09 36.5 0.1 1.1e-07 32.2 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CCH60954.1 - 0.18 12.5 0.1 23 5.7 0.0 2.7 3 0 0 3 3 3 0 Aspartyl protease BAG PF02179.16 CCH60955.1 - 5.5e-15 55.5 4.7 7.3e-15 55.2 4.7 1.2 1 0 0 1 1 1 1 BAG domain tRNA-synt_1f PF01921.18 CCH60955.1 - 0.034 13.1 0.1 0.036 13.0 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) ANAPC5 PF12862.7 CCH60955.1 - 0.12 12.4 0.6 0.2 11.7 0.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 FAD_binding_1 PF00667.20 CCH60956.1 - 6.8e-67 225.3 0.0 1.2e-66 224.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CCH60956.1 - 1.1e-07 32.5 0.0 2.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 CCH60956.1 - 0.00042 20.6 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 CCH60956.1 - 0.089 13.1 0.0 0.69 10.3 0.0 2.4 3 0 0 3 3 3 0 Oxidoreductase FAD-binding domain SMC_N PF02463.19 CCH60957.1 - 4e-61 206.3 43.7 2.1e-39 135.2 5.1 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCH60957.1 - 1.5e-18 67.2 0.1 6.9e-18 65.1 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CCH60957.1 - 7.4e-11 42.4 20.1 7.4e-11 42.4 20.1 4.3 2 2 2 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 CCH60957.1 - 5.3e-05 23.2 0.5 5.3e-05 23.2 0.5 4.6 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH60957.1 - 5.7e-05 22.8 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ADH_zinc_N_2 PF13602.6 CCH60957.1 - 0.1 13.7 0.3 11 7.1 0.0 3.9 4 1 1 5 5 5 0 Zinc-binding dehydrogenase DUF3866 PF12982.7 CCH60957.1 - 0.14 11.2 0.9 4.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3866) ABC_tran PF00005.27 CCH60957.1 - 0.56 10.7 0.0 0.56 10.7 0.0 6.7 4 2 2 6 6 6 0 ABC transporter Ribosomal_L29e PF01779.17 CCH60958.1 - 1.9e-24 85.7 8.6 2.7e-24 85.2 8.6 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Peptidase_C48 PF02902.19 CCH60959.1 - 4.3e-35 121.5 0.6 4.3e-35 121.5 0.6 2.8 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RINGv PF12906.7 CCH60960.1 - 7.5e-16 58.0 8.4 1.3e-15 57.2 8.4 1.4 1 0 0 1 1 1 1 RING-variant domain UvrD-helicase PF00580.21 CCH60960.1 - 0.051 13.1 4.2 0.037 13.6 1.8 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain FANCL_C PF11793.8 CCH60960.1 - 0.14 12.3 5.4 0.43 10.8 5.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 CCH60960.1 - 1.4 9.3 9.9 3 8.2 9.9 1.6 1 1 0 1 1 1 0 Ring finger domain ANAPC_CDC26 PF10471.9 CCH60961.1 - 1.3e-13 51.5 13.5 2.2e-13 50.8 13.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Sulfatase_C PF14707.6 CCH60961.1 - 0.032 15.0 0.6 0.034 14.9 0.6 1.2 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Luciferase_N PF05295.11 CCH60961.1 - 0.062 13.3 0.3 0.074 13.1 0.3 1.2 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Pex14_N PF04695.13 CCH60961.1 - 1.3 9.7 8.0 1.7 9.3 8.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FlxA PF14282.6 CCH60961.1 - 1.3 9.0 21.2 1.1 9.2 20.5 1.3 1 1 0 1 1 1 0 FlxA-like protein MMgT PF10270.9 CCH60962.1 - 1.2e-26 93.0 0.3 4.9e-26 91.0 0.3 1.7 1 1 0 1 1 1 1 Membrane magnesium transporter STAG PF08514.11 CCH60963.1 - 1e-22 80.2 2.7 1e-22 80.2 2.7 3.5 3 0 0 3 3 3 1 STAG domain Ipi1_N PF12333.8 CCH60963.1 - 0.06 13.9 1.2 0.54 10.9 0.0 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation AMPK1_CBM PF16561.5 CCH60964.1 - 1.2e-05 25.4 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Zip PF02535.22 CCH60965.1 - 7.8e-58 196.3 16.6 1e-48 166.3 9.9 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter AP3D1 PF06375.11 CCH60965.1 - 0.014 15.6 3.4 0.022 15.0 3.4 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 PPL5 PF18168.1 CCH60965.1 - 0.11 11.8 3.2 0.16 11.2 3.2 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NST1 PF13945.6 CCH60965.1 - 2.7 8.0 12.0 4.8 7.2 12.0 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Ferlin_C PF16165.5 CCH60965.1 - 3.5 7.6 4.7 28 4.6 0.4 2.9 3 0 0 3 3 3 0 Ferlin C-terminus SWIRM PF04433.17 CCH60966.1 - 6.7e-30 103.3 0.8 3.2e-29 101.1 0.2 2.5 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 CCH60966.1 - 1.2e-11 44.2 2.0 1.8e-11 43.6 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CCH60966.1 - 1.1e-09 38.3 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH60966.1 - 4.5e-08 33.2 1.4 2e-07 31.1 0.1 2.8 4 0 0 4 4 4 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CCH60966.1 - 5.3e-08 32.7 7.5 1.5e-07 31.3 7.5 1.8 1 0 0 1 1 1 1 SWIRM-associated region 1 zf-UBR PF02207.20 CCH60966.1 - 0.0041 17.3 0.6 0.0077 16.4 0.6 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-CCHC_2 PF13696.6 CCH60966.1 - 0.0068 16.2 4.5 0.69 9.8 0.2 2.3 2 0 0 2 2 2 2 Zinc knuckle Elf1 PF05129.13 CCH60966.1 - 0.043 13.9 0.4 0.12 12.4 0.4 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CdiI_N PF18228.1 CCH60966.1 - 0.36 10.7 3.8 5.5 6.9 0.0 2.9 1 1 1 3 3 3 0 CdiI N-terminal domain MADF_DNA_bdg PF10545.9 CCH60966.1 - 0.4 11.0 2.8 1.7 9.0 0.0 3.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SNF2_N PF00176.23 CCH60967.1 - 1.7e-60 204.6 0.3 1.7e-60 204.6 0.3 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH60967.1 - 4.2e-21 75.4 0.0 4.9e-19 68.7 0.0 3.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCH60967.1 - 0.0006 19.6 0.0 0.0021 17.9 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ploopntkinase1 PF18748.1 CCH60967.1 - 0.033 13.7 0.1 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 Erg28 PF03694.13 CCH60968.1 - 2.3e-43 147.1 3.6 2.9e-43 146.7 3.6 1.1 1 0 0 1 1 1 1 Erg28 like protein F_actin_cap_B PF01115.17 CCH60969.1 - 5.7e-86 288.0 2.0 6.5e-86 287.8 2.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit CDC24_OB1 PF17246.2 CCH60969.1 - 0.02 15.0 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 1 DUF5641 PF18701.1 CCH60969.1 - 0.024 14.8 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5641) bZIP_1 PF00170.21 CCH60971.1 - 9.5e-14 51.2 5.2 2.1e-13 50.1 5.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCH60971.1 - 1e-05 25.5 7.0 3e-05 24.0 7.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Hamartin PF04388.12 CCH60971.1 - 0.042 12.5 7.7 0.049 12.3 7.7 1.2 1 0 0 1 1 1 0 Hamartin protein bZIP_Maf PF03131.17 CCH60971.1 - 0.093 13.3 8.7 0.04 14.4 5.6 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor eRF1_2 PF03464.15 CCH60972.1 - 8.8e-25 87.6 0.1 1.4e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCH60972.1 - 9.3e-25 87.3 1.9 2.1e-24 86.2 0.1 2.5 3 1 0 3 3 3 1 eRF1 domain 3 eRF1_1 PF03463.15 CCH60972.1 - 1.7e-16 60.4 0.1 2.6e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 SNF2_N PF00176.23 CCH60972.1 - 0.061 12.0 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Rer1 PF03248.13 CCH60973.1 - 4.4e-71 238.1 11.3 5.1e-71 237.9 11.3 1.0 1 0 0 1 1 1 1 Rer1 family PHZA_PHZB PF03284.13 CCH60973.1 - 0.049 13.3 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B PQ-loop PF04193.14 CCH60974.1 - 5.8e-06 26.0 6.6 5.8e-06 26.0 6.6 4.4 5 0 0 5 5 5 2 PQ loop repeat Atthog PF18800.1 CCH60974.1 - 0.74 9.7 9.3 0.097 12.6 1.5 2.6 3 0 0 3 3 3 0 Attenuator of Hedgehog Saf_2TM PF18303.1 CCH60974.1 - 0.92 9.1 7.0 0.11 12.1 1.3 2.1 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain PLDc_2 PF13091.6 CCH60975.1 - 7.4e-17 61.5 0.0 1.5e-07 31.3 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CCH60975.1 - 1.3e-10 41.0 0.4 0.00027 21.0 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif cNMP_binding PF00027.29 CCH60976.1 - 5.6e-42 141.7 0.0 3.9e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CCH60976.1 - 2.4e-07 30.3 1.5 7.9e-07 28.6 1.5 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ALS_ss_C PF10369.9 CCH60978.1 - 9.5e-17 61.0 0.1 5.6e-16 58.5 0.0 2.4 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 CCH60978.1 - 2.1e-13 49.8 0.1 4.6e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CCH60978.1 - 2.4e-07 30.5 0.1 4.9e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 CCH60978.1 - 0.02 15.5 0.5 0.16 12.6 0.0 2.2 2 0 0 2 2 2 0 ACT domain Cofilin_ADF PF00241.20 CCH60978.1 - 0.11 12.4 0.1 0.43 10.4 0.0 1.9 1 1 1 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein Limkain-b1 PF11608.8 CCH60978.1 - 0.11 12.5 0.0 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 HMGL-like PF00682.19 CCH60978.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 HMGL-like Ribosomal_L27_C PF18471.1 CCH60979.1 - 2.8e-52 177.5 26.5 4.4e-52 176.9 26.5 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 CCH60979.1 - 1e-32 111.9 3.3 7.7e-32 109.2 0.3 2.4 2 0 0 2 2 2 1 Ribosomal L27 protein Helicase_IV_N PF12462.8 CCH60979.1 - 0.0044 17.0 5.6 0.0068 16.4 4.9 1.6 1 1 0 1 1 1 1 DNA helicase IV / RNA helicase N terminal DUF2924 PF11149.8 CCH60979.1 - 1.5 9.2 10.0 0.42 11.0 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) Cyclin_C PF02984.19 CCH60979.1 - 4.5 7.4 9.7 2.5 8.2 0.8 2.9 1 1 2 3 3 3 0 Cyclin, C-terminal domain DUF1325 PF07039.11 CCH60980.1 - 9.8e-39 132.5 0.0 8.4e-38 129.4 0.0 2.3 2 0 0 2 2 2 1 SGF29 tudor-like domain Agenet PF05641.12 CCH60980.1 - 2.2e-05 24.8 1.3 0.062 13.8 0.1 3.5 3 0 0 3 3 3 2 Agenet domain Tudor_3 PF18115.1 CCH60980.1 - 0.00052 19.8 0.0 0.0018 18.1 0.0 1.9 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 CCH60980.1 - 0.0087 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) PilZ PF07238.14 CCH60980.1 - 0.15 12.4 0.0 0.9 9.9 0.0 2.3 1 1 0 1 1 1 0 PilZ domain RP-C_C PF11800.8 CCH60980.1 - 9.6 6.2 7.8 15 5.6 0.3 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region RRM_1 PF00076.22 CCH60981.1 - 7.2e-57 189.1 0.0 2.4e-17 62.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CCH60981.1 - 4.7e-05 23.3 0.0 0.078 12.8 0.0 3.1 3 0 0 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 CCH60981.1 - 6.6e-05 22.5 0.0 2 8.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2015 PF09435.10 CCH60982.1 - 3e-35 120.4 0.1 3.7e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Sid-5 PF17204.3 CCH60982.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Sid-5 family WD40 PF00400.32 CCH60983.1 - 2.5e-44 148.3 16.4 3e-08 34.2 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 CCH60983.1 - 1.1e-13 50.8 7.4 0.0037 16.0 0.1 5.1 2 1 3 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCH60983.1 - 3e-13 49.9 0.5 0.029 14.7 0.3 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCH60983.1 - 1.1e-10 41.0 0.2 0.093 11.7 0.0 5.3 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CCH60983.1 - 2.6e-07 30.3 0.8 0.12 11.6 0.0 4.2 3 2 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Hira PF07569.11 CCH60983.1 - 8.1e-07 29.0 0.2 0.014 15.1 0.0 4.6 3 1 2 5 5 5 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 CCH60983.1 - 5.9e-06 25.3 2.3 0.24 10.1 0.1 4.3 2 1 2 4 4 4 2 Nup133 N terminal like Frtz PF11768.8 CCH60983.1 - 0.0011 17.4 0.0 0.0044 15.4 0.0 2.0 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CCH60983.1 - 0.0015 17.1 0.0 0.43 9.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Choline_sulf_C PF12411.8 CCH60983.1 - 0.0045 16.8 1.1 0.63 9.9 0.4 2.9 3 0 0 3 3 3 1 Choline sulfatase enzyme C terminal PALB2_WD40 PF16756.5 CCH60983.1 - 0.013 14.5 2.8 0.036 13.0 0.0 2.9 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DUF2373 PF10180.9 CCH60984.1 - 3e-22 78.2 2.8 5.6e-22 77.3 2.8 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Swm2 PF17083.5 CCH60985.1 - 7.2e-20 71.3 17.6 3.2e-11 43.4 5.6 3.2 2 1 1 3 3 3 3 Nucleolar protein Swm2 Arrestin_C PF02752.22 CCH60986.1 - 9.8e-19 68.1 0.6 9.8e-19 68.1 0.6 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCH60986.1 - 3.5e-10 40.1 0.2 2.1e-06 27.8 0.1 2.6 1 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCH60986.1 - 0.005 16.6 0.0 0.014 15.1 0.0 1.8 1 0 0 1 1 1 1 Arrestin_N terminal like ANAPC4_WD40 PF12894.7 CCH60987.1 - 2.1e-07 31.1 0.1 0.0034 17.7 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH60987.1 - 1.8e-06 28.5 0.0 0.21 12.5 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat DSPn PF14671.6 CCH60988.1 - 7.3e-47 159.4 0.2 2e-46 157.9 0.1 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CCH60988.1 - 7.6e-26 90.5 1.0 1.9e-24 86.0 0.0 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CCH60988.1 - 0.00014 22.0 0.1 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CCH60988.1 - 0.0012 18.5 0.0 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CCH60988.1 - 0.002 17.8 0.5 0.0037 16.9 0.1 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) RRM_1 PF00076.22 CCH60989.1 - 3.5e-38 129.3 4.1 8.2e-13 48.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCH60989.1 - 0.0017 18.4 1.0 1.6 8.8 0.0 4.0 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 CCH60989.1 - 0.0017 18.4 0.1 0.12 12.5 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CCH60989.1 - 0.0048 16.9 0.7 0.44 10.6 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Ysc84 PF04366.12 CCH60990.1 - 3.7e-42 143.1 0.1 8.9e-42 141.9 0.1 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCH60990.1 - 3.1e-16 58.7 0.1 6.4e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH60990.1 - 4.7e-13 48.8 0.0 1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH60990.1 - 1.8e-12 46.7 0.1 4.3e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain ProRS-C_1 PF09180.11 CCH60991.1 - 7.6e-26 90.1 1.3 2e-25 88.7 1.3 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CCH60991.1 - 2.4e-19 69.3 0.1 6.1e-19 68.0 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCH60991.1 - 6.1e-17 62.2 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CCH60991.1 - 0.00021 21.4 0.0 0.00083 19.4 0.0 1.9 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain DUF5341 PF17276.2 CCH60992.1 - 4.4e-22 79.0 7.6 7.4e-22 78.3 7.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5341) DUF2427 PF10348.9 CCH60992.1 - 4.5 7.1 5.6 9.7 6.0 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) SUR7 PF06687.12 CCH60993.1 - 1e-10 41.6 22.9 3.6e-10 39.8 22.9 1.9 1 0 0 1 1 1 1 SUR7/PalI family Wzy_C PF04932.15 CCH60993.1 - 0.046 13.4 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 O-Antigen ligase DUF2070 PF09843.9 CCH60993.1 - 0.19 9.9 12.8 0.34 9.1 8.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) WHIM1 PF15612.6 CCH60994.1 - 0.00021 20.8 0.1 0.00055 19.4 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SOBP PF15279.6 CCH60994.1 - 3.9 8.0 9.4 11 6.5 9.4 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein Pkinase PF00069.25 CCH60995.1 - 1.1e-70 238.1 0.0 1.6e-70 237.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH60995.1 - 5.4e-39 134.0 0.0 7.6e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH60995.1 - 0.00021 20.2 0.7 0.0032 16.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCH60995.1 - 0.0015 17.9 0.0 0.028 13.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CCH60995.1 - 0.047 12.7 0.2 3.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Seadornavirus VP7 ABC1 PF03109.16 CCH60995.1 - 0.088 13.0 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 ABC1 family Glycogen_syn PF05693.13 CCH60996.1 - 0 1113.4 0.0 0 1113.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CCH60996.1 - 7.5e-10 38.6 0.0 1.3e-06 28.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCH60996.1 - 3.6e-07 30.7 0.0 0.0023 18.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCH60996.1 - 1.8e-05 24.8 0.4 4.1e-05 23.6 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CCH60996.1 - 2.4e-05 24.9 0.2 6.4e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 CCH60996.1 - 0.00013 21.8 0.1 0.00029 20.6 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain SLT_L PF14718.6 CCH60997.1 - 0.18 12.0 0.2 0.36 11.0 0.2 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain PAP2_3 PF14378.6 CCH61000.1 - 1.8e-23 83.3 12.5 1.8e-23 83.3 12.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CCH61000.1 - 2.5e-09 37.0 8.7 2.5e-09 37.0 8.7 2.6 1 1 2 3 3 3 1 PAP2 superfamily RNB PF00773.19 CCH61001.1 - 1.7e-98 330.0 0.1 3.5e-98 329.0 0.0 1.5 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 CCH61001.1 - 7.6e-77 256.1 0.4 2e-76 254.7 0.4 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CCH61001.1 - 3.7e-29 100.5 1.2 3.7e-29 100.5 1.2 1.9 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 CCH61001.1 - 3.1e-17 62.4 0.0 8.3e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CCH61001.1 - 1.3e-14 54.6 2.3 3.6e-14 53.2 2.3 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CCH61001.1 - 1.7e-05 24.9 0.0 0.012 15.8 0.0 3.1 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 CCH61001.1 - 0.045 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain Dis3l2_C_term PF17877.1 CCH61001.1 - 0.37 11.1 3.2 0.18 12.1 0.3 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal Acetyltransf_13 PF13880.6 CCH61002.1 - 3.4e-17 62.2 0.0 3.3e-16 59.0 0.0 2.3 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CCH61002.1 - 2.3e-10 40.1 0.3 4.1e-10 39.3 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 CCH61002.1 - 0.00077 19.8 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCH61002.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCH61002.1 - 0.015 15.3 0.3 0.097 12.6 0.0 2.4 3 1 1 4 4 4 0 Acetyltransferase (GNAT) domain DUF2380 PF09533.10 CCH61002.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Acetyltransf_9 PF13527.7 CCH61002.1 - 0.16 12.1 0.0 7.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_65m PF03632.15 CCH61003.1 - 2.7e-36 125.2 1.0 4.8e-35 121.1 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CCH61003.1 - 2.4e-21 76.4 0.2 4.4e-21 75.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Gly_transf_sug PF04488.15 CCH61003.1 - 0.076 13.6 0.2 0.44 11.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase sugar-binding region containing DXD motif NPR1_interact PF15699.5 CCH61004.1 - 0.011 16.4 8.7 0.022 15.4 0.5 2.7 1 1 1 2 2 2 0 NPR1 interacting PA26 PF04636.13 CCH61004.1 - 2.3 7.0 12.0 3.2 6.6 11.9 1.4 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.16 CCH61004.1 - 3 6.6 3.9 3.5 6.4 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0086 PF01868.16 CCH61005.1 - 2e-23 82.1 0.0 4.6e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function UPF0086 SMC_N PF02463.19 CCH61005.1 - 0.052 13.0 0.8 0.09 12.2 0.8 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain CTP-dep_RFKase PF01982.16 CCH61005.1 - 0.055 13.6 2.1 0.13 12.3 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF120 COMPASS-Shg1 PF05205.12 CCH61006.1 - 9.8e-19 68.0 8.4 1.2e-18 67.7 8.4 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RhoGAP PF00620.27 CCH61007.1 - 6.3e-41 139.7 3.1 5e-40 136.8 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CCH61007.1 - 0.0013 18.9 1.4 0.0013 18.9 1.4 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain UBX PF00789.20 CCH61008.1 - 2.6e-08 34.0 0.0 4.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain Vps26 PF03643.15 CCH61009.1 - 1.6e-102 342.2 0.7 1.9e-102 342.0 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CCH61009.1 - 0.0019 18.3 0.6 0.025 14.6 0.4 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Imm19 PF15563.6 CCH61009.1 - 0.0046 16.5 0.2 0.0066 16.0 0.2 1.2 1 0 0 1 1 1 1 Immunity protein 19 Rgp1 PF08737.10 CCH61009.1 - 0.01 15.0 0.3 0.04 13.1 0.1 1.8 2 0 0 2 2 2 0 Rgp1 IL17R_D_N PF16742.5 CCH61009.1 - 0.056 13.5 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Gypsy PF07253.11 CCH61010.1 - 0.14 10.6 0.1 0.26 9.8 0.1 1.3 1 0 0 1 1 1 0 Gypsy protein Tim54 PF11711.8 CCH61011.1 - 1.3e-122 409.2 0.3 1.1e-121 406.2 0.3 1.9 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Lysine_decarbox PF03641.14 CCH61012.1 - 3.9e-43 146.7 0.0 6.2e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CCH61012.1 - 8.2e-11 41.7 0.0 1.1e-10 41.3 0.0 1.3 1 1 0 1 1 1 1 SLOG cluster4 family Methyltransf_16 PF10294.9 CCH61013.1 - 2.1e-22 79.7 0.0 3.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCH61013.1 - 8.3e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH61013.1 - 0.0028 17.5 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH61013.1 - 0.025 15.3 0.0 0.049 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CCH61013.1 - 0.066 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CCH61013.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.25 CCH61014.1 - 9.7e-29 100.5 0.1 2e-27 96.2 0.1 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61014.1 - 2.5e-18 66.3 0.0 1.3e-17 64.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PhnA_Zn_Ribbon PF08274.12 CCH61014.1 - 0.098 12.6 0.3 0.25 11.3 0.3 1.7 1 0 0 1 1 1 0 PhnA Zinc-Ribbon HbrB PF08539.11 CCH61015.1 - 4.2e-33 114.7 1.8 4.2e-33 114.7 1.8 2.5 2 0 0 2 2 2 1 HbrB-like Lact-deh-memb PF09330.11 CCH61015.1 - 0.015 14.6 0.1 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding DUF2457 PF10446.9 CCH61015.1 - 0.3 10.2 18.2 0.53 9.4 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 CCH61015.1 - 0.94 9.5 8.9 1.6 8.8 8.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 CCH61015.1 - 1.9 7.8 7.9 3.3 6.9 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein Lin-8 PF03353.15 CCH61015.1 - 4.9 6.6 10.2 0.34 10.4 4.4 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PI3K_1B_p101 PF10486.9 CCH61015.1 - 5.5 4.6 9.7 7.6 4.2 9.7 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CLN3 PF02487.17 CCH61016.1 - 1.6e-121 406.1 27.7 4.9e-120 401.2 27.7 2.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CCH61016.1 - 0.00067 18.7 18.0 0.00067 18.7 18.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1674 PF07896.12 CCH61017.1 - 7.6e-19 67.9 7.2 2.4e-18 66.4 7.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) adh_short PF00106.25 CCH61018.1 - 7.5e-18 64.7 0.0 1.2e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 CCH61018.1 - 6.8e-09 35.9 0.0 1.7e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CCH61018.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 CCH61018.1 - 0.18 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Esterase PF00756.20 CCH61019.1 - 2.2e-24 86.5 0.1 2.6e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 CCH61019.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 CCH61019.1 - 0.2 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 CCH61020.1 - 2.4e-34 119.1 0.0 2.9e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CCH61020.1 - 0.01 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.13 CCH61020.1 - 0.17 11.6 2.8 0.89 9.2 2.8 2.0 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 CCH61021.1 - 4e-32 111.9 0.0 5e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 CCH61021.1 - 0.0064 16.2 0.2 0.014 15.1 0.2 1.5 1 1 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.21 CCH61021.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.11 CCH61021.1 - 0.077 12.3 0.1 0.89 8.8 0.1 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) WD40 PF00400.32 CCH61022.1 - 2.4e-11 44.0 0.1 0.0017 19.2 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61022.1 - 1.1e-07 32.0 0.0 0.32 11.3 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Sld5 PF05916.11 CCH61023.1 - 2.6e-17 63.3 1.7 4.3e-17 62.5 1.7 1.4 1 0 0 1 1 1 1 GINS complex protein Mem_trans PF03547.18 CCH61025.1 - 2.2e-66 223.9 16.4 4.5e-66 222.8 16.4 1.5 1 1 0 1 1 1 1 Membrane transport protein Cytokin_check_N PF10407.9 CCH61026.1 - 5.1e-30 103.2 5.2 1.6e-29 101.7 5.2 2.0 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.26 CCH61027.1 - 3.4e-17 63.5 4.4 3.4e-17 63.5 4.4 1.9 1 1 1 2 2 2 1 Cysteine-rich secretory protein family KH_1 PF00013.29 CCH61028.1 - 4.4e-58 193.0 42.0 5.1e-10 39.0 2.5 10.7 11 1 0 11 11 11 7 KH domain SLS PF14611.6 CCH61028.1 - 0.033 14.0 34.5 0.0096 15.8 4.4 5.9 4 2 2 6 6 6 0 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 CCH61028.1 - 0.32 10.9 9.3 0.19 11.6 0.1 4.2 5 0 0 5 5 5 0 KH domain Actin PF00022.19 CCH61029.1 - 3.7e-95 318.9 0.1 1.8e-92 310.1 0.1 3.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCH61029.1 - 0.0001 21.3 0.0 0.014 14.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein DDHD PF02862.17 CCH61029.1 - 0.11 12.7 5.9 0.43 10.7 2.7 2.2 2 0 0 2 2 2 0 DDHD domain Macoilin PF09726.9 CCH61029.1 - 0.77 8.2 13.6 0.72 8.3 7.7 2.0 2 0 0 2 2 2 0 Macoilin family DUF3808 PF10300.9 CCH61030.1 - 6e-148 493.5 4.5 7.3e-148 493.2 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 CCH61030.1 - 0.024 14.9 1.0 7.9 6.8 0.0 4.8 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CCH61030.1 - 0.059 13.9 0.8 0.48 11.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.8 CCH61030.1 - 0.1 12.8 0.2 0.1 12.8 0.2 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 TPR_2 PF07719.17 CCH61030.1 - 0.33 11.2 3.3 7.6 6.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 CCH61031.1 - 0.00097 19.1 0.6 0.0065 16.4 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CCH61031.1 - 0.69 9.6 0.0 0.69 9.6 0.0 2.2 3 0 0 3 3 3 0 EF hand Vps51 PF08700.11 CCH61032.1 - 4.7e-07 29.8 0.3 4.7e-07 29.8 0.3 1.8 2 0 0 2 2 2 1 Vps51/Vps67 RNA_pol_Rpb1_5 PF04998.17 CCH61032.1 - 0.0016 18.0 1.9 0.0018 17.7 1.9 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Arrestin_C PF02752.22 CCH61033.1 - 1.3e-13 51.5 0.4 1.3e-13 51.5 0.4 4.4 5 0 0 5 5 5 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCH61033.1 - 1e-07 32.1 0.0 2.9e-05 24.1 0.0 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain OTCace PF00185.24 CCH61034.1 - 8.7e-50 168.9 0.2 1.4e-49 168.1 0.2 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CCH61034.1 - 6.2e-43 146.3 0.1 1.1e-42 145.6 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain TetR_C_8 PF14278.6 CCH61034.1 - 0.039 14.1 0.3 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region Zn_clus PF00172.18 CCH61035.1 - 2.7e-11 43.4 10.6 4.3e-11 42.8 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LT-IIB PF06453.11 CCH61035.1 - 0.049 13.5 0.6 0.13 12.1 0.6 1.7 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) BRCT PF00533.26 CCH61036.1 - 6.2e-10 39.3 15.8 0.00057 20.2 0.6 5.1 4 2 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCH61036.1 - 2.6e-08 34.2 10.0 0.00025 21.4 2.6 4.5 4 1 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CCH61036.1 - 6.4e-05 22.8 0.3 0.063 13.2 0.1 3.5 3 0 0 3 3 3 2 twin BRCT domain UvrD-helicase PF00580.21 CCH61037.1 - 3.6e-64 217.3 0.3 3.6e-64 217.3 0.3 3.1 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CCH61037.1 - 5.4e-43 147.7 1.4 1.3e-40 139.8 0.0 3.6 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CCH61037.1 - 1.4e-28 100.1 0.0 3.3e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CCH61037.1 - 1.3e-07 31.4 0.1 0.0012 18.6 0.0 2.8 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CCH61037.1 - 0.00049 19.9 0.0 0.0039 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CCH61037.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Helicase Ribosomal_L21p PF00829.21 CCH61038.1 - 2e-06 28.0 0.0 2.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SAPS PF04499.15 CCH61039.1 - 2.6e-150 501.5 17.3 2.6e-150 501.5 17.3 3.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein IF-2B PF01008.17 CCH61040.1 - 1.1e-74 251.1 0.0 1.3e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 CCH61040.1 - 0.12 12.3 0.1 11 6.0 0.0 2.6 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sin_N PF04801.13 CCH61041.1 - 7.6e-17 61.6 1.5 1.2e-16 61.0 1.5 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region Calpain_inhib PF00748.19 CCH61041.1 - 0.029 14.9 0.5 0.058 13.9 0.5 1.6 1 0 0 1 1 1 0 Calpain inhibitor UPA_2 PF17809.1 CCH61041.1 - 0.17 11.7 0.5 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 UPA domain DEAD PF00270.29 CCH61042.1 - 4.7e-40 137.2 0.0 8.6e-40 136.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61042.1 - 3.7e-20 72.3 0.4 1.4e-19 70.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCH61042.1 - 2.7e-17 62.8 0.1 6.2e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCH61042.1 - 7e-06 26.2 2.2 1.4e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pam16 PF03656.13 CCH61043.1 - 4.7e-46 155.9 4.2 5.4e-46 155.7 4.2 1.1 1 0 0 1 1 1 1 Pam16 NTP_transferase PF00483.23 CCH61043.1 - 0.0038 16.8 0.2 0.0048 16.5 0.2 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase MLD PF11647.8 CCH61043.1 - 0.012 15.9 0.8 1.7 9.0 0.1 2.4 1 1 1 2 2 2 0 Membrane Localization Domain PHD PF00628.29 CCH61044.1 - 1.1e-08 34.8 7.4 2.4e-08 33.8 7.4 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CCH61044.1 - 2.2e-05 24.9 10.5 2.2e-05 24.9 10.5 3.4 2 2 0 2 2 2 1 SET domain PHD_2 PF13831.6 CCH61044.1 - 0.12 12.0 2.4 0.22 11.1 2.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-CW PF07496.15 CCH61044.1 - 0.14 12.2 1.1 0.42 10.7 1.1 1.9 1 0 0 1 1 1 0 CW-type Zinc Finger GATA PF00320.27 CCH61045.1 - 9.8e-16 57.1 3.3 2.2e-15 55.9 3.3 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCH61045.1 - 0.013 15.0 0.4 0.027 14.0 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CCH61045.1 - 0.25 11.5 0.5 0.42 10.8 0.5 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Cpn60_TCP1 PF00118.24 CCH61046.1 - 2.6e-155 517.8 4.3 2.9e-155 517.6 4.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CCH61046.1 - 0.027 13.7 0.7 0.055 12.7 0.1 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Herpes_U59 PF04529.12 CCH61046.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus U59 protein PNTB_4TM PF12769.7 CCH61046.1 - 0.19 12.2 0.0 0.47 10.9 0.0 1.6 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 CCH61047.1 - 4.6e-12 46.0 0.0 9.3e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH61047.1 - 9.5e-05 22.2 0.3 0.0013 18.6 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 CCH61047.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.32 CCH61048.1 - 7.1e-19 67.8 8.7 0.0012 19.6 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61048.1 - 1e-06 28.9 1.1 0.12 12.7 0.0 4.2 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GIT_CC PF16559.5 CCH61048.1 - 0.01 15.7 1.6 0.047 13.6 1.6 2.3 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4894 PF16235.5 CCH61048.1 - 0.077 13.4 4.9 0.15 12.4 3.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4894) DUF1647 PF07801.11 CCH61048.1 - 0.89 9.3 6.0 1.3 8.7 3.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) SUN PF03856.13 CCH61049.1 - 2.5e-83 279.3 5.8 3.7e-83 278.7 5.8 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.9 CCH61049.1 - 0.58 8.7 5.1 0.61 8.6 5.1 1.1 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 CCH61049.1 - 0.68 8.1 16.1 0.97 7.6 16.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.13 CCH61049.1 - 3.9 5.4 15.6 6 4.8 15.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Lectin_leg-like PF03388.13 CCH61050.1 - 3.9e-08 32.9 0.1 3.4e-07 29.8 0.3 2.0 2 0 0 2 2 2 1 Legume-like lectin family Bact_lectin PF18483.1 CCH61050.1 - 0.00021 21.3 1.0 0.00034 20.7 1.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Alb1 PF09135.11 CCH61052.1 - 5.6e-08 33.6 11.4 5.6e-08 33.6 11.4 1.7 1 1 1 2 2 2 1 Alb1 DUF5427 PF10310.9 CCH61053.1 - 6e-113 378.3 35.1 7e-113 378.0 35.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF2956 PF11169.8 CCH61053.1 - 0.15 12.3 0.2 0.15 12.3 0.2 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2956) LSM PF01423.22 CCH61054.1 - 5e-16 58.1 0.3 9.6e-16 57.2 0.3 1.4 1 0 0 1 1 1 1 LSM domain PUF PF00806.19 CCH61054.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat GCD14 PF08704.10 CCH61055.1 - 2.7e-80 269.6 5.1 3.9e-78 262.5 5.1 2.9 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CCH61055.1 - 5e-05 23.1 0.2 0.00013 21.8 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CCH61055.1 - 0.00026 20.2 0.0 0.00066 18.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CCH61055.1 - 0.001 19.7 0.0 0.0028 18.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH61055.1 - 0.0052 16.6 0.2 0.013 15.4 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain GCD14_N PF14801.6 CCH61055.1 - 0.021 14.7 0.0 0.066 13.1 0.0 1.9 2 0 0 2 2 1 0 tRNA methyltransferase complex GCD14 subunit N-term PCMT PF01135.19 CCH61055.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ta0938 PF11494.8 CCH61055.1 - 0.029 14.6 1.1 2.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Ta0938 Methyltransf_11 PF08241.12 CCH61055.1 - 0.075 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FliX PF10768.9 CCH61055.1 - 0.076 13.5 0.5 0.14 12.6 0.5 1.4 1 0 0 1 1 1 0 Class II flagellar assembly regulator CEP63 PF17045.5 CCH61055.1 - 0.14 12.0 7.8 0.21 11.4 7.8 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Siah-Interact_N PF09032.11 CCH61055.1 - 0.29 11.5 3.6 0.55 10.6 1.1 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal Atg14 PF10186.9 CCH61055.1 - 0.68 9.0 8.9 0.23 10.5 6.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 CCH61056.1 - 1.2e-60 205.1 0.1 3.6e-60 203.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61056.1 - 7.7e-36 123.7 0.0 1.5e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH61056.1 - 0.00027 20.4 0.0 0.00027 20.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCH61056.1 - 0.099 11.4 0.0 0.099 11.4 0.0 3.2 3 0 0 3 3 3 0 Fungal protein kinase TrkH PF02386.16 CCH61057.1 - 2.7e-153 511.1 13.2 7.4e-151 503.0 7.7 2.3 2 0 0 2 2 2 2 Cation transport protein Caps_assemb_Wzi PF14052.6 CCH61057.1 - 0.092 11.8 3.1 0.24 10.4 0.1 2.3 2 0 0 2 2 2 0 Capsule assembly protein Wzi FRB_dom PF08771.11 CCH61057.1 - 0.15 12.5 2.7 1.9 8.9 0.4 2.8 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain Zn_dep_PLPC PF00882.18 CCH61058.1 - 6.4e-21 75.2 2.6 1.2e-20 74.2 2.6 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C Mito_carr PF00153.27 CCH61059.1 - 3.6e-58 193.5 4.3 2.4e-19 69.1 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.21 CCH61060.1 - 5.6e-18 65.0 3.9 5.6e-18 65.0 3.9 1.9 2 0 0 2 2 2 1 PAP2 superfamily Fer4_5 PF12801.7 CCH61060.1 - 6.2 6.9 10.3 1.3 9.0 3.6 3.0 1 1 1 2 2 2 0 4Fe-4S binding domain AAA_6 PF12774.7 CCH61061.1 - 1.4e-82 277.3 0.0 1.1e-81 274.4 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CCH61061.1 - 2.7e-74 250.7 18.8 2.7e-74 250.7 18.8 6.2 5 2 0 5 5 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CCH61061.1 - 1.2e-49 168.4 8.3 1.2e-49 168.4 8.3 4.0 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CCH61061.1 - 5.8e-47 159.5 1.6 2e-38 131.7 0.0 4.7 5 0 0 5 5 4 3 P-loop containing dynein motor region AAA_8 PF12780.7 CCH61061.1 - 5.7e-45 153.7 0.8 5.7e-45 153.7 0.8 3.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 CCH61061.1 - 2.8e-26 92.3 31.3 2.8e-26 92.3 31.3 5.2 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 CCH61061.1 - 7.6e-26 90.8 0.0 8.3e-08 32.3 0.0 6.5 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) MT PF12777.7 CCH61061.1 - 6.4e-25 87.9 4.5 1.6e-24 86.6 4.5 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 CCH61061.1 - 5.5e-19 68.6 0.2 2.7e-18 66.3 0.2 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CCH61061.1 - 1.3e-17 64.4 7.3 6.9e-05 23.3 0.0 7.2 7 0 0 7 7 6 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH61061.1 - 1.3e-14 54.6 6.0 0.00035 20.9 0.0 6.4 5 1 0 5 5 5 3 AAA domain AAA_16 PF13191.6 CCH61061.1 - 2.2e-07 31.4 0.0 0.35 11.2 0.0 4.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_19 PF13245.6 CCH61061.1 - 5.4e-07 30.0 0.9 0.091 13.1 0.0 4.3 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.6 CCH61061.1 - 1.5e-06 28.3 8.6 0.017 15.1 0.0 7.4 7 0 0 7 7 5 1 AAA domain AAA_33 PF13671.6 CCH61061.1 - 4.4e-06 26.9 0.0 0.011 15.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CCH61061.1 - 1.6e-05 24.7 0.0 2 8.1 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CCH61061.1 - 1.8e-05 25.3 15.3 0.06 13.9 0.0 7.3 8 0 0 8 8 6 2 AAA domain Sigma54_activat PF00158.26 CCH61061.1 - 2.9e-05 23.8 0.4 3 7.5 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain Dynein_heavy PF03028.15 CCH61061.1 - 4.3e-05 23.6 0.3 0.0047 17.0 0.2 3.8 3 1 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain RNA_helicase PF00910.22 CCH61061.1 - 6.2e-05 23.3 0.0 4.4 7.7 0.0 4.8 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 CCH61061.1 - 0.00014 21.1 9.9 0.018 14.1 0.1 3.7 4 0 0 4 4 3 2 Type II/IV secretion system protein AAA_24 PF13479.6 CCH61061.1 - 0.00034 20.4 1.9 0.42 10.3 0.0 4.5 4 0 0 4 4 4 1 AAA domain cobW PF02492.19 CCH61061.1 - 0.00061 19.4 0.3 0.097 12.3 0.0 3.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 CCH61061.1 - 0.00062 20.3 0.8 7.6 7.1 0.0 4.9 4 0 0 4 4 4 0 ABC transporter IstB_IS21 PF01695.17 CCH61061.1 - 0.00062 19.5 0.1 2 8.1 0.0 3.9 4 0 0 4 4 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 CCH61061.1 - 0.00072 19.3 0.0 17 5.1 0.0 4.4 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CCH61061.1 - 0.001 18.4 0.0 4.4 6.5 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin AAA_lid_1 PF17857.1 CCH61061.1 - 0.0035 17.5 0.0 0.069 13.4 0.0 3.5 1 0 0 1 1 1 1 AAA+ lid domain NTPase_1 PF03266.15 CCH61061.1 - 0.0062 16.5 1.0 3.5 7.5 0.0 3.7 3 0 0 3 3 3 1 NTPase Guanylate_kin PF00625.21 CCH61061.1 - 0.013 15.2 6.4 6.4 6.4 0.0 5.2 5 0 0 5 5 4 0 Guanylate kinase Mg_chelatase PF01078.21 CCH61061.1 - 0.015 14.7 0.0 0.83 9.0 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 CCH61061.1 - 0.016 15.3 0.1 5.3 7.2 0.0 4.0 3 0 0 3 3 3 0 Sigma-54 interaction domain ResIII PF04851.15 CCH61061.1 - 0.021 14.8 17.0 0.11 12.5 0.0 7.2 8 0 0 8 8 6 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CCH61061.1 - 0.03 14.2 0.5 2.2 8.2 0.0 3.7 4 0 0 4 4 3 0 NACHT domain DEAD PF00270.29 CCH61061.1 - 0.044 13.5 0.1 16 5.2 0.1 3.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.6 CCH61061.1 - 1.1 8.8 2.1 2.3 7.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain Ras PF00071.22 CCH61062.1 - 8.7e-36 123.0 0.0 1.3e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH61062.1 - 3.6e-22 78.8 0.0 7.7e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH61062.1 - 2.6e-08 33.5 0.0 5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 CCH61062.1 - 0.00068 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CCH61062.1 - 0.007 16.6 0.1 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCH61062.1 - 0.0077 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CCH61062.1 - 0.0093 16.0 0.0 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH61062.1 - 0.014 15.3 2.6 1.1 9.1 0.0 2.8 1 1 1 3 3 3 0 RsgA GTPase MCM PF00493.23 CCH61062.1 - 0.025 13.7 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain NACHT PF05729.12 CCH61062.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 CCH61062.1 - 0.064 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CCH61062.1 - 0.082 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CCH61062.1 - 0.089 12.4 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CCH61062.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA_U5-meth_tr PF05958.11 CCH61063.1 - 8.6e-23 80.9 0.2 4.4e-22 78.5 0.2 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 CCH61063.1 - 1.2e-11 44.4 0.0 2.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 CCH61063.1 - 2.3e-07 30.7 0.1 6.1e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CCH61063.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CCH61063.1 - 8.8e-05 23.1 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CCH61063.1 - 0.00023 20.8 0.1 0.00086 19.0 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 CCH61063.1 - 0.0038 16.8 0.0 0.0086 15.7 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CCH61063.1 - 0.007 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CCH61063.1 - 0.0071 16.1 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CCH61063.1 - 0.016 15.9 0.0 0.041 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SusE PF14292.6 CCH61063.1 - 0.087 13.1 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 SusE outer membrane protein Ribosomal_S21e PF01249.18 CCH61064.1 - 1.7e-38 130.6 0.1 1.9e-38 130.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e VCH_CASS14 PF18315.1 CCH61064.1 - 0.072 13.1 0.0 0.18 11.9 0.0 1.6 1 1 1 2 2 2 0 Integron cassette protein VCH_CASS1 chain Glyco_transf_8 PF01501.20 CCH61065.1 - 2.8e-23 82.8 4.8 2.8e-23 82.8 4.8 3.4 3 1 1 4 4 4 1 Glycosyl transferase family 8 DEAD PF00270.29 CCH61066.1 - 4.1e-44 150.5 1.7 9.2e-44 149.3 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61066.1 - 2.3e-31 108.4 0.4 7.5e-31 106.8 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH61066.1 - 2.7e-07 30.7 0.0 5.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCH61066.1 - 0.0075 16.6 0.1 0.1 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH61066.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L10 PF00466.20 CCH61066.1 - 0.044 13.9 0.1 1.2 9.3 0.0 3.0 2 1 1 3 3 3 0 Ribosomal protein L10 Glyco_transf_15 PF01793.16 CCH61067.1 - 5.9e-100 334.7 8.6 7e-100 334.4 8.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.25 CCH61068.1 - 2.5e-48 164.7 0.5 5.1e-48 163.7 0.5 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61068.1 - 1.7e-18 66.9 0.0 4.8e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCH61068.1 - 0.00097 19.1 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCH61068.1 - 0.0011 18.6 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 CCH61068.1 - 0.047 13.2 0.2 0.13 11.7 0.2 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NOA36 PF06524.12 CCH61068.1 - 0.095 12.0 23.9 0.18 11.1 23.9 1.5 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 CCH61068.1 - 1.5 8.1 15.8 3.1 7.0 15.8 1.5 1 0 0 1 1 1 0 BUD22 Tim17 PF02466.19 CCH61069.1 - 3.4e-31 107.9 6.1 4.2e-31 107.6 6.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.24 CCH61071.1 - 5.1e-164 546.4 33.0 5.9e-164 546.2 33.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH61071.1 - 6.5e-33 114.1 30.9 4.5e-30 104.8 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH61071.1 - 0.0061 15.0 1.6 0.0061 15.0 1.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 CCH61071.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Arylesterase PF01731.20 CCH61071.1 - 0.43 10.8 2.1 0.69 10.1 0.1 2.3 3 0 0 3 3 3 0 Arylesterase Sugar_tr PF00083.24 CCH61072.1 - 2.7e-158 527.6 32.2 3.2e-158 527.3 32.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH61072.1 - 5.8e-33 114.3 31.6 4.1e-29 101.6 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH61072.1 - 0.004 15.6 1.7 0.004 15.6 1.7 1.8 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) Peptidase_C39_2 PF13529.6 CCH61073.1 - 0.14 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family Hexokinase_2 PF03727.16 CCH61074.1 - 1.1e-79 267.3 0.0 1.4e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCH61074.1 - 9e-69 231.4 0.0 3.1e-68 229.6 0.0 1.9 3 0 0 3 3 3 1 Hexokinase Sec63 PF02889.16 CCH61075.1 - 7.9e-27 94.0 3.7 7.9e-27 94.0 3.7 1.8 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.29 CCH61075.1 - 1.9e-25 89.7 0.0 4.4e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CCH61075.1 - 4e-13 49.7 1.9 6.6e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCH61075.1 - 1.5e-12 47.9 0.3 1.1e-11 45.0 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCH61075.1 - 0.00026 21.3 0.0 0.0012 19.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH61075.1 - 0.017 15.5 0.0 0.052 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 CCH61075.1 - 0.029 13.9 0.0 0.029 13.9 0.0 3.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.6 CCH61075.1 - 0.035 13.9 1.4 0.29 10.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CCH61075.1 - 0.094 11.8 0.0 0.22 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CCH61075.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2420 PF10336.9 CCH61076.1 - 3e-33 114.1 2.7 6.2e-33 113.1 2.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 CCH61077.1 - 3.5e-15 56.1 1.1 5.2e-15 55.5 1.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCH61077.1 - 7.2e-09 35.7 3.3 1.3e-08 34.9 1.5 2.1 2 0 0 2 2 2 1 Clathrin adaptor complex small chain NAD_binding_6 PF08030.12 CCH61077.1 - 7.7 6.6 8.9 11 6.1 6.0 2.8 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Proteasome PF00227.26 CCH61078.1 - 9.5e-27 93.7 0.2 1.2e-26 93.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit AP_endonuc_2 PF01261.24 CCH61078.1 - 0.021 14.3 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel PDEase_II PF02112.15 CCH61079.1 - 1.5e-55 188.7 2.0 4.1e-33 114.9 0.1 2.6 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 CCH61079.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Surface_antigen PF11054.8 CCH61079.1 - 0.08 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Sporozoite TA4 surface antigen Brr6_like_C_C PF10104.9 CCH61080.1 - 1.6e-38 131.5 1.7 2.2e-38 131.0 1.7 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RAI1 PF08652.11 CCH61081.1 - 5.4e-25 87.4 0.3 1.1e-24 86.4 0.3 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.21 CCH61082.1 - 1.8e-120 401.6 0.1 2.4e-120 401.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CCH61082.1 - 2.4e-39 135.0 1.9 6.8e-39 133.5 0.8 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 CCH61082.1 - 6.4e-10 39.3 2.2 2.2e-09 37.5 2.2 2.0 1 0 0 1 1 1 1 Glutamate--tRNA ligase N-terminal domain GST_C_2 PF13410.6 CCH61082.1 - 9.3e-05 22.4 0.0 0.00026 20.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCH61082.1 - 0.0095 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PocR PF10114.9 CCH61082.1 - 0.027 14.2 0.1 3.5 7.4 0.0 2.4 1 1 1 2 2 2 0 Sensory domain found in PocR tRNA-synt_1e PF01406.19 CCH61082.1 - 0.031 13.6 0.2 0.099 12.0 0.1 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF155 PF02582.14 CCH61083.1 - 4.5e-54 183.2 0.1 9e-54 182.2 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Plus-3 PF03126.18 CCH61084.1 - 1.2e-23 83.7 1.2 2e-23 83.0 0.1 2.1 2 0 0 2 2 2 1 Plus-3 domain TEA PF01285.18 CCH61084.1 - 0.38 10.9 3.9 0.49 10.5 1.1 2.5 2 0 0 2 2 2 0 TEA/ATTS domain A_deamin PF02137.18 CCH61085.1 - 4.1e-30 105.4 0.1 5.4e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain IBN_N PF03810.19 CCH61086.1 - 3.7e-09 36.4 1.3 1.3e-07 31.5 0.2 4.0 5 0 0 5 5 5 1 Importin-beta N-terminal domain ANAPC10 PF03256.16 CCH61087.1 - 2.8e-37 128.1 0.4 3.9e-37 127.7 0.4 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 CCH61087.1 - 0.00048 20.4 2.9 0.00048 20.4 2.9 2.1 1 1 1 2 2 2 1 PITH domain CBFB_NFYA PF02045.15 CCH61088.1 - 9.4e-25 87.0 6.3 1.6e-24 86.3 6.3 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GARS_A PF01071.19 CCH61089.1 - 2.7e-78 262.2 0.0 4.5e-78 261.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CCH61089.1 - 3.8e-34 117.4 0.0 1.7e-33 115.3 0.0 2.2 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CCH61089.1 - 6.6e-33 114.0 0.0 1.3e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CCH61089.1 - 1.4e-21 76.6 0.0 4.3e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CCH61089.1 - 9.2e-17 61.5 1.0 6.2e-16 58.8 1.5 2.1 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 CCH61089.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CCH61089.1 - 0.00024 20.7 0.0 0.00068 19.2 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CCH61089.1 - 0.0035 17.4 0.0 0.017 15.2 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 CCH61089.1 - 0.014 15.0 0.3 0.061 12.9 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 CCH61089.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CCH61089.1 - 0.085 12.4 0.1 0.69 9.4 0.0 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Mito_carr PF00153.27 CCH61090.1 - 1.2e-34 118.1 9.0 1.5e-14 53.7 0.4 3.9 3 2 0 3 3 3 3 Mitochondrial carrier protein Sec15 PF04091.12 CCH61091.1 - 2.8e-103 345.7 14.7 2.8e-103 345.7 14.7 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like THUMP PF02926.17 CCH61092.1 - 7.3e-24 84.5 2.4 7.3e-24 84.5 2.4 1.9 1 1 1 2 2 2 1 THUMP domain DUF1077 PF06417.12 CCH61093.1 - 9.9e-42 141.7 1.8 1.3e-41 141.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF2417 PF10329.9 CCH61094.1 - 0.033 13.6 0.7 0.037 13.4 0.7 1.2 1 1 0 1 1 1 0 Region of unknown function (DUF2417) SAPS PF04499.15 CCH61095.1 - 1.3e-142 476.0 22.9 1.3e-142 476.0 22.9 3.2 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein AdoHcyase PF05221.17 CCH61097.1 - 4.3e-130 433.2 0.0 2.3e-74 250.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CCH61097.1 - 1.6e-84 281.9 2.5 2.6e-84 281.2 2.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCH61097.1 - 1.8e-07 30.7 0.1 3.3e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CCH61097.1 - 0.00045 19.8 0.3 0.00085 18.9 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CCH61097.1 - 0.003 17.8 0.1 0.0057 16.9 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.19 CCH61097.1 - 0.051 12.3 1.1 0.41 9.3 0.2 2.2 1 1 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase SPRY PF00622.28 CCH61098.1 - 8.9e-23 80.7 1.7 1.2e-22 80.3 0.2 2.0 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 CCH61098.1 - 2.2e-13 50.3 5.7 2.2e-13 50.3 5.7 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain DpnI_C PF17726.1 CCH61098.1 - 0.0096 16.0 1.6 0.0096 16.0 1.6 2.7 2 0 0 2 2 2 1 Dam-replacing HTH domain LisH PF08513.11 CCH61098.1 - 0.037 14.0 0.6 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 LisH Ost5 PF05251.12 CCH61099.1 - 5.2e-16 58.7 8.6 5.9e-16 58.5 8.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 ADH_N PF08240.12 CCH61100.1 - 9.7e-25 86.6 4.7 2.2e-24 85.5 4.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH61100.1 - 2.2e-20 72.9 0.3 4.6e-20 71.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CCH61100.1 - 0.0021 17.4 0.7 0.0037 16.6 0.7 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CCH61100.1 - 0.0054 17.8 0.0 0.01 16.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCH61100.1 - 0.006 16.0 0.1 0.0098 15.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CCH61100.1 - 0.033 13.8 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GATA PF00320.27 CCH61101.1 - 1.9e-15 56.2 4.2 3.9e-15 55.2 4.2 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCH61101.1 - 2 8.0 6.5 0.14 11.7 0.7 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding EamA PF00892.20 CCH61102.1 - 1.2e-06 28.7 31.9 0.0012 19.0 8.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 CCH61102.1 - 2.6 8.8 12.8 0.38 11.4 5.2 2.8 3 0 0 3 3 3 0 Small Multidrug Resistance protein Nse5 PF08691.10 CCH61103.1 - 1.7e-14 53.4 29.9 2.9e-14 52.6 29.9 1.3 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Hydrolase PF00702.26 CCH61104.1 - 2.8e-07 31.1 0.0 4.5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCH61104.1 - 0.00014 22.0 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prefoldin_2 PF01920.20 CCH61105.1 - 4.6e-23 81.2 11.8 5.5e-23 80.9 11.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit MscS_porin PF12795.7 CCH61105.1 - 0.0038 16.8 3.3 0.016 14.8 0.2 2.0 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF1192 PF06698.11 CCH61105.1 - 0.0048 16.9 1.1 0.021 14.8 1.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) UPF0242 PF06785.11 CCH61105.1 - 0.093 12.8 10.2 0.12 12.5 10.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_3 PF13758.6 CCH61105.1 - 0.1 12.7 4.1 0.48 10.5 4.1 2.1 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 CCH61105.1 - 0.13 12.8 1.2 0.69 10.4 0.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.6 CCH61105.1 - 0.19 12.4 5.4 2.7 8.7 5.4 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Cortex-I_coil PF09304.10 CCH61105.1 - 0.2 11.9 7.3 0.76 10.0 0.6 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil pRN1_helical PF13010.6 CCH61105.1 - 0.21 11.6 2.4 0.3 11.0 2.4 1.3 1 0 0 1 1 1 0 Primase helical domain DUF641 PF04859.12 CCH61105.1 - 0.35 11.2 7.7 0.42 10.9 3.1 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ABC_tran_CTD PF16326.5 CCH61105.1 - 0.51 10.6 9.4 1 9.7 1.2 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain OmpH PF03938.14 CCH61105.1 - 0.52 10.7 11.1 4.5 7.6 11.2 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 CCH61105.1 - 0.52 10.2 9.4 6.1 6.8 9.4 2.2 1 1 0 1 1 1 0 Prefoldin subunit FliJ PF02050.16 CCH61105.1 - 0.59 10.4 7.8 2.3 8.5 0.8 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Spc24 PF08286.11 CCH61105.1 - 0.74 10.1 6.7 4 7.7 0.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Bcr-Abl_Oligo PF09036.10 CCH61105.1 - 0.76 9.8 4.3 0.58 10.2 0.6 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Seryl_tRNA_N PF02403.22 CCH61105.1 - 0.78 10.0 10.2 0.78 10.0 2.6 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.6 CCH61105.1 - 0.91 9.8 5.8 1.3 9.4 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) PEARLI-4 PF05278.12 CCH61105.1 - 0.93 9.0 8.1 1.1 8.8 1.6 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) APG6_N PF17675.1 CCH61105.1 - 1.3 9.6 10.5 9.1 6.8 10.5 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 CCH61105.1 - 2 8.8 7.8 3.4 8.1 1.5 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 CCH61105.1 - 3.7 8.0 8.0 7 7.1 0.6 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 CCH61105.1 - 4.7 7.9 10.0 90 3.8 10.0 2.2 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YojJ PF10372.9 CCH61105.1 - 4.9 7.3 6.7 1.3 9.2 1.1 2.2 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus COQ9 PF08511.11 CCH61106.1 - 7.9e-22 76.8 0.9 3.7e-21 74.7 0.6 2.2 2 0 0 2 2 2 1 COQ9 SCF PF02404.15 CCH61106.1 - 0.015 14.7 0.3 0.024 14.0 0.3 1.3 1 0 0 1 1 1 0 Stem cell factor Cornichon PF03311.14 CCH61107.1 - 2.6e-43 147.2 11.5 3e-43 147.0 11.5 1.0 1 0 0 1 1 1 1 Cornichon protein CENP-X PF09415.10 CCH61108.1 - 9.4e-24 83.5 1.6 1.3e-23 83.1 1.6 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 CCH61108.1 - 0.00067 19.9 0.3 0.0013 18.9 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ENTH PF01417.20 CCH61109.1 - 5.3e-38 129.9 0.1 9.9e-38 129.0 0.1 1.5 1 0 0 1 1 1 1 ENTH domain DUF1713 PF08213.11 CCH61110.1 - 1e-11 44.5 22.8 1.4e-11 44.1 22.8 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) zf-Mss51 PF13824.6 CCH61111.1 - 1.5e-16 60.2 1.0 3.1e-16 59.2 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 NOT2_3_5 PF04153.18 CCH61112.1 - 6.5e-30 103.9 1.7 6.5e-30 103.9 1.7 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Nop14 PF04147.12 CCH61112.1 - 0.00063 18.1 11.9 0.00071 17.9 11.9 1.0 1 0 0 1 1 1 1 Nop14-like family F-protein PF00469.20 CCH61112.1 - 0.023 14.3 3.4 0.04 13.5 3.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef RRN3 PF05327.11 CCH61112.1 - 0.026 13.1 8.0 0.028 13.0 8.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5580 PF17743.1 CCH61112.1 - 0.03 12.9 10.0 0.041 12.4 10.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Vfa1 PF08432.10 CCH61112.1 - 0.077 13.3 12.1 0.11 12.8 12.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 CCH61112.1 - 0.12 12.5 4.7 0.17 12.1 4.7 1.3 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.6 CCH61112.1 - 0.33 9.6 9.5 0.44 9.2 9.5 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 CCH61112.1 - 0.64 8.2 17.7 0.88 7.8 17.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 CCH61112.1 - 0.91 8.1 4.9 1.1 7.8 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 CCH61112.1 - 1.1 8.2 10.1 1.4 7.8 10.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 CCH61112.1 - 1.5 7.5 12.2 2.3 6.9 12.2 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 CCH61112.1 - 1.9 7.2 8.6 3.1 6.5 8.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CCH61112.1 - 2.4 7.3 10.9 3.4 6.8 10.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LAP1C PF05609.12 CCH61112.1 - 2.7 7.0 13.6 3.3 6.7 13.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 CCH61112.1 - 8 4.9 13.1 9.8 4.6 13.1 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CCH61112.1 - 8.3 5.1 15.5 9.9 4.9 15.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_18 PF13238.6 CCH61113.1 - 4.3e-28 98.4 0.4 7.1e-28 97.7 0.1 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCH61113.1 - 1.3e-05 25.7 0.0 5.5e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CCH61113.1 - 0.00045 20.7 0.2 0.0026 18.2 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH61113.1 - 0.0012 19.3 0.0 0.0014 19.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH61113.1 - 0.0014 18.9 0.1 0.0027 18.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCH61113.1 - 0.0015 18.8 0.0 0.0042 17.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CCH61113.1 - 0.0015 18.2 0.2 1 9.0 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 CCH61113.1 - 0.016 14.5 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 CCH61113.1 - 0.019 15.4 0.2 0.076 13.4 0.0 2.0 2 1 1 3 3 3 0 RNA helicase KTI12 PF08433.10 CCH61113.1 - 0.023 14.2 0.1 0.098 12.1 0.0 1.9 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 CCH61113.1 - 0.037 14.2 0.1 7.7 6.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 CCH61113.1 - 0.12 12.4 0.1 0.57 10.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CCH61113.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CCH61113.1 - 0.29 11.6 3.8 5.7 7.5 3.8 2.1 1 1 0 1 1 1 0 ABC transporter Cyclin_N PF00134.23 CCH61114.1 - 9.9e-42 141.7 1.4 2.1e-41 140.6 1.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCH61114.1 - 3.4e-18 65.8 0.0 1.2e-17 64.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CCH61115.1 - 6.3e-39 132.6 0.1 3.1e-38 130.4 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCH61115.1 - 1.5e-32 112.2 0.0 3.8e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain IF-2B PF01008.17 CCH61116.1 - 3e-79 266.2 0.0 3.6e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ATP-synt_S1 PF05827.12 CCH61117.1 - 0.00089 19.1 0.1 0.003 17.4 0.0 1.9 2 0 0 2 2 2 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SwrA PF17423.2 CCH61117.1 - 0.0056 16.7 1.7 0.013 15.5 1.7 1.6 1 0 0 1 1 1 1 Swarming motility protein CdiA_C PF18451.1 CCH61117.1 - 0.035 14.3 1.3 2.8 8.2 0.1 3.2 2 1 1 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain YiaAB PF05360.14 CCH61117.1 - 0.12 12.6 1.4 0.34 11.2 1.4 1.8 1 0 0 1 1 1 0 yiaA/B two helix domain DUF3397 PF11877.8 CCH61117.1 - 0.25 11.6 0.1 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) Pescadillo_N PF06732.11 CCH61118.1 - 5.8e-122 406.5 0.9 5.8e-122 406.5 0.9 2.2 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CCH61118.1 - 3.7e-11 43.3 0.0 1.2e-10 41.7 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CCH61118.1 - 0.00037 20.8 0.0 0.0014 19.0 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CCH61118.1 - 0.0051 17.1 0.0 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Rhomboid PF01694.22 CCH61119.1 - 2.2e-32 112.1 16.4 2.2e-32 112.1 16.4 1.8 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.18 CCH61120.1 - 1.5e-55 188.2 0.9 3.9e-55 186.8 0.9 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CCH61120.1 - 6.3e-16 58.3 0.1 1.7e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 CCH61120.1 - 0.00022 20.9 1.3 0.02 14.8 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CCH61120.1 - 0.0045 17.4 1.5 0.032 14.7 1.5 2.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CCH61120.1 - 0.0056 16.1 0.8 0.077 12.6 0.1 2.9 2 0 0 2 2 2 1 EF hand Vps36_ESCRT-II PF11605.8 CCH61120.1 - 0.021 15.0 0.0 0.064 13.4 0.0 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Telomere_reg-2 PF10193.9 CCH61121.1 - 3.3e-21 75.8 2.7 9.4e-21 74.3 0.3 2.6 2 1 0 2 2 2 1 Telomere length regulation protein RRG8 PF17068.5 CCH61122.1 - 1.9e-37 129.2 9.8 2.3e-37 128.9 9.8 1.0 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial Cas6_N PF17952.1 CCH61123.1 - 0.01 16.1 0.4 0.01 16.1 0.4 3.6 4 0 0 4 4 4 0 Cas6 N-terminal domain SUIM_assoc PF16619.5 CCH61123.1 - 0.02 14.9 1.9 0.12 12.4 1.9 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PX PF00787.24 CCH61124.1 - 1.8e-22 79.5 0.0 2.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 PX domain CBFD_NFYB_HMF PF00808.23 CCH61125.1 - 1.4e-16 60.5 0.2 1.9e-16 60.1 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCH61125.1 - 2.6e-08 34.3 0.5 3.4e-08 33.9 0.5 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CCH61125.1 - 0.036 14.4 0.2 0.055 13.8 0.2 1.2 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TraF PF13728.6 CCH61125.1 - 0.46 10.3 4.8 0.64 9.8 4.4 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF3453 PF11935.8 CCH61126.1 - 6.7e-46 156.7 4.7 3.4e-44 151.2 4.7 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3453) SR-25 PF10500.9 CCH61126.1 - 0.0057 16.3 12.3 0.0057 16.3 12.3 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Oxidored_FMN PF00724.20 CCH61127.1 - 4.3e-116 387.9 0.0 5e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GCV_H PF01597.19 CCH61128.1 - 1.5e-43 147.5 0.6 1.8e-43 147.3 0.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CCH61128.1 - 0.011 15.6 0.9 0.052 13.4 0.3 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme eIF2A PF08662.11 CCH61129.1 - 3.6e-22 79.2 1.6 8.4e-11 42.1 0.2 3.8 3 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CCH61129.1 - 5.8e-05 22.8 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CCH61129.1 - 0.26 12.3 1.8 2.7e+02 2.7 0.0 5.0 5 1 1 6 6 6 0 WD domain, G-beta repeat Proteasome PF00227.26 CCH61130.1 - 1.2e-53 181.5 0.0 1.8e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH61130.1 - 5.9e-12 45.0 0.0 5.9e-12 45.0 0.0 2.2 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.18 CCH61131.1 - 2.2e-10 40.5 10.0 4e-10 39.6 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma54_DBD PF04552.13 CCH61131.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.6 3 0 0 3 3 3 0 Sigma-54, DNA binding domain Phage_GP20 PF06810.11 CCH61132.1 - 0.016 15.0 4.3 0.039 13.8 4.3 1.6 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF641 PF04859.12 CCH61132.1 - 0.056 13.8 2.5 0.093 13.1 0.7 2.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) IZUMO PF15005.6 CCH61132.1 - 0.37 11.3 4.8 0.36 11.3 1.6 2.1 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated AMP-binding PF00501.28 CCH61133.1 - 2.3e-89 299.9 0.1 2.8e-89 299.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCH61133.1 - 1.1e-23 84.0 0.0 1.4e-22 80.4 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCH61133.1 - 2.6e-16 59.3 0.8 5.5e-16 58.2 0.8 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Kelch_6 PF13964.6 CCH61134.1 - 2.2e-09 37.3 1.8 0.31 11.4 0.0 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CCH61134.1 - 2.6e-06 26.9 6.6 0.26 10.9 0.2 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CCH61134.1 - 9.7e-06 25.5 2.9 0.26 11.3 0.1 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCH61134.1 - 6e-05 22.9 0.1 3.1 7.9 0.0 4.3 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CCH61134.1 - 0.00027 20.8 4.7 2 8.5 0.5 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CCH61134.1 - 0.012 15.9 0.1 4.2 7.8 0.0 3.3 2 0 0 2 2 2 0 Galactose oxidase, central domain LRR_4 PF12799.7 CCH61136.1 - 4.1e-13 49.3 21.8 8e-07 29.3 1.6 7.0 5 1 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCH61136.1 - 1.1e-07 31.5 15.4 1.5e-05 24.6 2.3 5.6 2 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 CCH61136.1 - 0.047 13.8 9.3 70 3.9 0.0 7.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_9 PF14580.6 CCH61136.1 - 0.091 12.3 13.6 0.11 12.0 2.2 3.7 2 1 1 3 3 3 0 Leucine-rich repeat WD40 PF00400.32 CCH61137.1 - 2.3e-25 88.3 21.1 5.2e-05 23.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61137.1 - 8.7e-20 70.8 0.8 1.4e-06 28.5 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCH61137.1 - 2e-05 23.8 0.0 0.0057 15.7 0.0 2.9 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCH61137.1 - 3.4e-05 23.8 0.3 0.3 10.9 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CCH61137.1 - 0.016 14.6 0.0 4.2 6.6 0.0 3.1 2 1 0 3 3 3 0 WD40-like domain Nbas_N PF15492.6 CCH61137.1 - 0.035 13.4 0.1 0.6 9.4 0.0 2.5 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal NPC1_N PF16414.5 CCH61138.1 - 6e-77 258.5 10.6 1.2e-76 257.6 10.6 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CCH61138.1 - 9e-34 116.7 20.5 1.2e-20 73.3 7.0 2.5 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CCH61138.1 - 4.9e-28 97.9 8.0 4.9e-28 97.9 8.0 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Ly49 PF08391.10 CCH61138.1 - 0.034 14.5 2.3 0.088 13.2 1.1 2.4 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF446 PF04287.12 CCH61138.1 - 0.56 10.3 2.5 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 tRNA pseudouridine synthase C Bap31_Bap29_C PF18035.1 CCH61138.1 - 0.85 9.7 2.0 0.78 9.8 0.2 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2701 PF10857.8 CCH61138.1 - 2.5 8.2 6.8 4.1 7.5 1.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) PT PF04886.12 CCH61139.1 - 1.8e-08 33.8 92.5 5.1e-06 25.9 0.8 10.1 2 2 3 5 5 5 4 PT repeat Ribosomal_L21p PF00829.21 CCH61139.1 - 7.5e-06 26.1 0.1 3.8 7.8 0.0 4.8 5 0 0 5 5 5 2 Ribosomal prokaryotic L21 protein Flocculin_t3 PF13928.6 CCH61139.1 - 0.00013 22.3 34.4 0.00052 20.5 7.9 15.5 5 3 9 14 14 14 5 Flocculin type 3 repeat Rhodanese_C PF12368.8 CCH61139.1 - 2.2 8.7 13.2 15 6.0 0.0 5.0 3 1 1 5 5 5 0 Rhodanase C-terminal Arv1 PF04161.13 CCH61139.1 - 2.4 8.3 10.6 43 4.2 0.1 4.9 5 0 0 5 5 5 0 Arv1-like family Prenyltrans PF00432.21 CCH61140.1 - 1.1e-53 178.6 5.3 1.2e-11 44.1 0.2 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CCH61140.1 - 5.9e-06 25.6 0.0 1.3 8.1 0.0 4.7 2 1 3 5 5 5 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CCH61140.1 - 1.1e-05 24.8 0.0 0.0002 20.6 0.0 2.1 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CCH61140.1 - 0.0045 16.0 0.0 0.57 9.1 0.0 2.6 2 1 0 2 2 2 2 A-macroglobulin TED domain DUF4375 PF14300.6 CCH61140.1 - 0.12 12.6 0.1 0.73 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) DNA_pol_E_B PF04042.16 CCH61141.1 - 4.4e-47 160.2 0.4 7.2e-47 159.5 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Nitr_red_bet_C PF14711.6 CCH61142.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal NBP1 PF08537.10 CCH61144.1 - 1.6e-110 369.7 37.4 1.8e-110 369.6 37.4 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 AAA PF00004.29 CCH61145.1 - 3.2e-43 147.3 0.0 6.7e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CCH61145.1 - 2.2e-30 104.4 0.3 6.7e-30 102.9 0.2 2.0 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CCH61145.1 - 2.8e-22 78.6 5.0 2.8e-22 78.6 5.0 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CCH61145.1 - 2.2e-07 30.5 0.0 2.6e-05 23.9 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 CCH61145.1 - 5e-06 26.4 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCH61145.1 - 6.7e-06 26.6 0.2 0.001 19.4 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CCH61145.1 - 3.7e-05 23.7 0.0 0.00015 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCH61145.1 - 5.5e-05 23.5 0.3 0.0012 19.1 0.1 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 CCH61145.1 - 6.5e-05 22.2 0.0 0.00025 20.3 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCH61145.1 - 0.0001 22.1 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CCH61145.1 - 0.00011 22.2 0.0 0.00041 20.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CCH61145.1 - 0.00012 21.5 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CCH61145.1 - 0.00021 21.6 0.0 0.0087 16.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CCH61145.1 - 0.00049 20.6 0.2 0.0013 19.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CCH61145.1 - 0.00076 19.6 0.1 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCH61145.1 - 0.0025 18.0 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCH61145.1 - 0.0038 17.0 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCH61145.1 - 0.013 15.9 1.4 0.03 14.7 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 CCH61145.1 - 0.017 14.7 0.2 0.24 11.0 0.1 2.3 1 1 0 2 2 2 0 AAA domain Torsin PF06309.11 CCH61145.1 - 0.024 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_7 PF12775.7 CCH61145.1 - 0.027 14.0 0.0 0.067 12.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CCH61145.1 - 0.032 13.6 1.4 5.4 6.3 0.0 2.8 2 1 1 3 3 3 0 KaiC Mg_chelatase PF01078.21 CCH61145.1 - 0.035 13.5 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CCH61145.1 - 0.061 12.6 0.2 1.1 8.5 0.1 2.6 1 1 2 3 3 3 0 Zeta toxin T2SSE PF00437.20 CCH61145.1 - 0.072 12.1 0.0 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 CCH61145.1 - 0.074 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 CCH61145.1 - 0.084 12.8 0.0 0.75 9.7 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 CCH61145.1 - 0.085 12.6 0.0 0.27 10.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CCH61145.1 - 0.094 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.12 CCH61145.1 - 0.12 12.2 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Methyltransf_32 PF13679.6 CCH61145.1 - 0.15 12.0 0.4 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ATPase_2 PF01637.18 CCH61145.1 - 0.71 9.7 3.4 2.3 8.1 0.0 2.8 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea PWWP PF00855.17 CCH61146.1 - 6.2e-18 65.0 0.6 2.3e-17 63.2 0.0 2.3 2 0 0 2 2 2 1 PWWP domain Thymidylat_synt PF00303.19 CCH61147.1 - 3.9e-115 383.6 0.0 4.5e-115 383.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.11 CCH61148.1 - 1.6e-14 53.5 11.8 2.3e-14 53.0 9.1 2.6 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 CCH61148.1 - 2.8e-09 36.6 10.9 1.2e-08 34.6 10.9 2.2 1 0 0 1 1 1 1 Shugoshin C terminus TSC22 PF01166.18 CCH61148.1 - 0.25 11.7 6.5 0.28 11.5 2.2 3.3 3 1 0 3 3 3 0 TSC-22/dip/bun family Nucleoporin_N PF08801.11 CCH61149.1 - 2.1e-49 168.5 10.9 3.7e-49 167.6 10.9 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CCH61149.1 - 8.7e-22 77.6 21.5 1.8e-21 76.5 21.5 1.4 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Brix PF04427.18 CCH61150.1 - 1e-38 133.4 0.3 1.4e-38 132.9 0.3 1.2 1 0 0 1 1 1 1 Brix domain DUF1086 PF06461.11 CCH61150.1 - 0.04 13.8 1.7 0.071 13.0 0.3 2.0 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1086) RabGAP-TBC PF00566.18 CCH61151.1 - 1.2e-51 175.4 4.5 1.2e-51 175.4 4.5 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ArAE_1_C PF11728.8 CCH61151.1 - 0.083 12.9 1.1 0.18 11.8 1.1 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Pneumovirus_M2 PF06436.11 CCH61151.1 - 0.11 12.0 1.0 0.32 10.5 0.3 2.1 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) SelP_N PF04592.14 CCH61151.1 - 1.1 8.7 14.3 2 7.7 14.3 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lactamase_B_4 PF13691.6 CCH61152.1 - 8.6e-25 86.2 0.0 2e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CCH61152.1 - 5.1e-09 35.9 0.0 0.00055 19.5 0.0 2.6 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Vps5 PF09325.10 CCH61153.1 - 1.9e-66 224.0 11.5 1.9e-66 224.0 11.5 2.1 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CCH61153.1 - 2.6e-22 78.9 0.4 1.5e-21 76.5 0.0 2.5 3 0 0 3 3 3 1 PX domain BAR_3_WASP_bdg PF10456.9 CCH61153.1 - 0.012 15.1 0.5 0.054 12.9 0.5 2.2 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Ribosomal_L18_c PF14204.6 CCH61153.1 - 4.5 8.3 8.1 4.5 8.3 0.2 3.8 3 1 0 3 3 3 0 Ribosomal L18 C-terminal region RecG_N PF17190.4 CCH61153.1 - 7.6 7.3 9.9 2.5 8.9 0.7 4.1 3 1 1 4 4 4 0 RecG N-terminal helical domain Ribosomal_L3 PF00297.22 CCH61154.1 - 5.7e-188 624.4 9.8 6.5e-188 624.2 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Big_3_3 PF13750.6 CCH61154.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) HRI1 PF16815.5 CCH61155.1 - 2e-44 152.0 0.7 2.3e-44 151.8 0.7 1.0 1 0 0 1 1 1 1 Protein HRI1 Cellulase PF00150.18 CCH61156.1 - 8.7e-15 54.9 6.5 1.7e-14 53.9 6.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NUFIP1 PF10453.9 CCH61156.1 - 0.14 12.1 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1708 PF08101.11 CCH61157.1 - 1.6e-141 472.4 15.4 1.6e-141 472.4 15.4 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF1708) Ras PF00071.22 CCH61158.1 - 4.8e-50 169.3 0.0 6e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH61158.1 - 2.1e-30 105.4 0.1 5.8e-30 104.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH61158.1 - 3.9e-11 42.7 0.0 5.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 CCH61158.1 - 0.00097 19.5 0.2 0.0083 16.5 0.2 2.2 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CCH61158.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCH61158.1 - 0.0048 16.3 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCH61158.1 - 0.012 15.2 0.2 0.059 12.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CCH61158.1 - 0.019 14.1 1.9 1.5 7.9 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 CCH61158.1 - 0.021 14.3 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 CCH61158.1 - 0.029 14.3 0.1 9.2 6.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 CCH61158.1 - 0.029 13.7 0.3 0.043 13.1 0.3 1.2 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 CCH61158.1 - 0.03 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CCH61158.1 - 0.052 13.0 0.0 0.087 12.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CCH61158.1 - 0.063 13.0 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CCH61158.1 - 0.074 13.1 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CCH61158.1 - 0.093 12.9 0.4 0.22 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCH61158.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TPR_2 PF07719.17 CCH61159.1 - 0.007 16.4 0.1 0.066 13.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH61159.1 - 0.017 15.9 0.1 0.038 14.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat IF-2B PF01008.17 CCH61160.1 - 1.3e-76 257.5 0.2 5.2e-76 255.5 0.2 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family Focal_AT PF03623.13 CCH61160.1 - 0.016 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Focal adhesion targeting region Fes1 PF08609.10 CCH61160.1 - 0.096 13.6 2.1 0.22 12.4 2.1 1.6 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Syntaxin_2 PF14523.6 CCH61160.1 - 1.3 9.4 6.7 11 6.4 3.1 2.6 1 1 1 2 2 2 0 Syntaxin-like protein NAD_binding_10 PF13460.6 CCH61161.1 - 7.9e-07 29.1 0.0 6.1e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CCH61161.1 - 9.5e-06 25.2 0.0 2.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CCH61161.1 - 5e-05 22.9 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CCH61161.1 - 0.0006 19.1 0.0 0.0019 17.4 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CCH61161.1 - 0.0009 18.3 0.0 0.0034 16.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CCH61161.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.6 CCH61161.1 - 0.0059 16.2 0.0 0.089 12.3 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 CCH61161.1 - 0.032 13.3 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain Ribosomal_S30 PF04758.14 CCH61162.1 - 1.7e-30 104.9 6.1 1.9e-30 104.8 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.6 CCH61163.1 - 6.1e-37 127.6 3.9 8.4e-37 127.2 3.9 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Inos-1-P_synth PF01658.17 CCH61163.1 - 0.04 14.2 0.6 0.13 12.5 0.6 2.0 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Rogdi_lz PF10259.9 CCH61163.1 - 0.084 12.3 5.1 0.55 9.6 0.2 2.3 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein FACT-Spt16_Nlob PF14826.6 CCH61163.1 - 0.1 12.4 13.2 0.083 12.7 1.1 2.7 3 0 0 3 3 3 0 FACT complex subunit SPT16 N-terminal lobe domain SlyX PF04102.12 CCH61163.1 - 0.16 12.6 0.1 43 4.8 0.0 2.8 2 0 0 2 2 2 0 SlyX DNTTIP1_dimer PF18192.1 CCH61163.1 - 0.98 9.8 6.4 0.2 12.0 0.9 2.6 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain WH1 PF00568.23 CCH61164.1 - 2e-34 117.9 0.0 2.8e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CCH61164.1 - 3.8e-06 26.5 0.8 1.6e-05 24.6 1.0 2.0 2 0 0 2 2 2 1 WH2 motif Glyco_hydro_18 PF00704.28 CCH61165.1 - 3.6e-25 89.4 0.7 1.2e-24 87.7 0.3 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CCH61165.1 - 1.3e-08 34.6 3.4 1.3e-08 34.6 3.4 4.6 4 1 1 5 5 5 1 Carbohydrate binding domain (family 19) DUF1199 PF06712.11 CCH61165.1 - 0.82 9.8 3.9 0.76 9.8 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1199) Methyltransf_16 PF10294.9 CCH61166.1 - 2.8e-11 43.5 0.0 1.5e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCH61166.1 - 0.00043 20.1 0.0 0.00062 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CCH61166.1 - 0.004 16.6 0.0 0.0062 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) ECH_1 PF00378.20 CCH61167.1 - 1.1e-16 60.9 0.0 1.4e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCH61167.1 - 4.5e-12 46.1 0.0 5.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Init_tRNA_PT PF04179.12 CCH61167.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Ribosomal_L39 PF00832.20 CCH61167.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L39 protein ECH_1 PF00378.20 CCH61168.1 - 1.5e-14 54.0 0.0 2.1e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCH61168.1 - 3.7e-08 33.3 0.0 5.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Init_tRNA_PT PF04179.12 CCH61168.1 - 0.018 15.3 1.1 0.027 14.8 0.1 1.8 2 0 0 2 2 2 0 Rit1 DUSP-like domain DUF1640 PF07798.11 CCH61169.1 - 1.1e-21 77.7 3.9 1.6e-21 77.2 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LRRFIP PF09738.9 CCH61169.1 - 4.6 6.6 9.4 15 5.0 9.6 1.6 1 1 0 1 1 1 0 LRRFIP family RF-1 PF00472.20 CCH61170.1 - 9.4e-21 73.9 7.8 1.9e-20 73.0 7.8 1.5 1 1 0 1 1 1 1 RF-1 domain Fungal_trans PF04082.18 CCH61171.1 - 2.5e-10 39.8 1.6 3.5e-10 39.4 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH61171.1 - 3.6e-05 23.8 11.0 3.6e-05 23.8 11.0 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP2 PF01569.21 CCH61171.1 - 0.2 11.4 4.4 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 PAP2 superfamily CBM_21 PF03370.13 CCH61172.1 - 2e-21 76.3 13.6 2e-21 76.3 13.6 2.6 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) DUF4746 PF15928.5 CCH61172.1 - 0.011 15.2 11.8 0.017 14.5 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CBM53 PF16760.5 CCH61172.1 - 0.017 15.7 10.1 0.017 15.7 10.1 3.6 2 1 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) PBP_sp32 PF07222.12 CCH61172.1 - 0.021 14.3 12.0 0.048 13.1 12.0 1.6 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FYDLN_acid PF09538.10 CCH61172.1 - 2.1 9.1 23.2 7.6 7.3 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF853 PF05872.12 CCH61172.1 - 3.8 6.0 5.6 5.9 5.4 5.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Tim54 PF11711.8 CCH61172.1 - 6.5 5.4 16.6 20 3.8 16.6 1.8 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTR2 PF00854.21 CCH61173.1 - 6.2e-102 341.4 11.0 1e-100 337.4 10.9 2.5 1 1 1 2 2 2 1 POT family MFS_1 PF07690.16 CCH61173.1 - 5.4e-09 35.4 10.9 2.1e-07 30.2 3.6 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily TMEM237 PF15383.6 CCH61173.1 - 0.031 13.4 0.1 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 237 SLATT_1 PF18181.1 CCH61173.1 - 0.14 12.1 0.6 2 8.4 0.0 2.8 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 PPV_E1_N PF00524.18 CCH61174.1 - 0.062 13.7 0.5 0.12 12.8 0.5 1.4 1 0 0 1 1 1 0 E1 Protein, N terminal domain SET PF00856.28 CCH61175.1 - 4.3e-12 46.7 0.0 1.1e-11 45.5 0.0 1.7 1 1 0 1 1 1 1 SET domain Cofilin_ADF PF00241.20 CCH61176.1 - 3.1e-40 136.7 0.5 3.5e-40 136.6 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.17 CCH61176.1 - 0.0008 19.7 0.1 0.0013 19.0 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain MitMem_reg PF13012.6 CCH61177.1 - 0.049 14.1 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF5344 PF17279.2 CCH61177.1 - 0.099 13.2 3.6 1 10.0 0.1 2.7 3 1 0 3 3 3 0 Family of unknown function (DUF5344) NPV_P10 PF05531.12 CCH61177.1 - 1.4 9.4 4.5 0.68 10.4 0.3 2.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Pneumo_M2 PF07380.11 CCH61178.1 - 0.03 14.6 0.1 0.14 12.4 0.1 2.2 1 0 0 1 1 1 0 Pneumovirus M2 protein RRM_1 PF00076.22 CCH61179.1 - 1.2e-14 53.9 5.1 3.8e-06 26.6 1.9 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_Crp_2 PF13545.6 CCH61179.1 - 0.031 14.2 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain RRM_Rrp7 PF17799.1 CCH61179.1 - 0.091 12.6 0.1 15 5.4 0.0 2.6 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain PITH PF06201.13 CCH61180.1 - 7.3e-34 117.2 1.9 9.1e-34 116.9 1.9 1.1 1 0 0 1 1 1 1 PITH domain MHC_I_2 PF14586.6 CCH61180.1 - 0.02 14.8 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 PHC2_SAM_assoc PF16616.5 CCH61182.1 - 0.081 13.7 0.6 0.24 12.2 0.6 1.8 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 PWI PF01480.17 CCH61182.1 - 0.081 13.3 4.3 0.074 13.4 1.2 2.5 2 0 0 2 2 2 0 PWI domain DUF668 PF05003.12 CCH61182.1 - 0.22 12.0 0.9 1.3 9.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF668) pXO2-72 PF17443.2 CCH61182.1 - 6.4 7.1 7.2 11 6.3 0.5 3.4 3 1 0 3 3 3 0 Uncharacterized protein pXO2-72 PALP PF00291.25 CCH61183.1 - 6e-66 222.8 0.0 6.9e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CTP_transf_like PF01467.26 CCH61184.1 - 3.4e-31 108.4 0.0 6e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Pannexin_like PF12534.8 CCH61184.1 - 0.15 11.1 1.4 0.21 10.6 1.4 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Macoilin PF09726.9 CCH61184.1 - 0.94 8.0 5.3 1.2 7.6 5.3 1.1 1 0 0 1 1 1 0 Macoilin family CTP_transf_like PF01467.26 CCH61185.1 - 5e-27 94.9 0.1 2.2e-21 76.5 0.1 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CCH61185.1 - 0.0078 16.1 1.5 1.4 8.8 0.3 3.1 2 1 0 2 2 2 1 FAD synthetase DUF4112 PF13430.6 CCH61186.1 - 2.8e-29 101.5 0.2 3.9e-29 101.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF3819 PF12842.7 CCH61186.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) FAM220 PF15487.6 CCH61186.1 - 0.24 11.0 3.3 0.39 10.3 3.3 1.3 1 0 0 1 1 1 0 FAM220 family Pex24p PF06398.11 CCH61187.1 - 6.6e-92 308.3 11.9 8.4e-92 308.0 11.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-CCCH PF00642.24 CCH61188.1 - 9.9e-09 34.9 3.9 9.9e-09 34.9 3.9 1.7 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 CCH61188.1 - 3.6e-07 29.9 10.0 3.6e-07 29.9 10.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 CCH61188.1 - 1.6e-05 24.6 3.9 3.9e-05 23.3 3.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CCH61188.1 - 2.1e-05 24.4 7.7 4.8e-05 23.3 7.7 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_3 PF13920.6 CCH61188.1 - 3.7e-05 23.5 8.4 6.4e-05 22.7 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH61188.1 - 4.3e-05 23.4 11.3 8.1e-05 22.5 11.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCH61188.1 - 5.5e-05 22.9 13.4 0.00013 21.7 13.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH61188.1 - 5.6e-05 22.9 7.3 0.00012 21.9 7.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CCH61188.1 - 0.00038 20.7 9.4 0.00038 20.7 9.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CCH61188.1 - 0.00081 19.4 7.4 0.00081 19.4 7.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 CCH61188.1 - 0.001 18.8 7.1 0.0022 17.8 7.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 CCH61188.1 - 0.0087 16.2 7.4 0.0087 16.2 7.4 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 CCH61188.1 - 0.017 15.0 3.7 0.039 13.8 3.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_2 PF14608.6 CCH61188.1 - 0.059 13.9 5.2 0.17 12.4 5.2 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-P11 PF03854.14 CCH61188.1 - 0.06 13.0 7.2 0.11 12.2 7.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger Ribosomal_L40e PF01020.17 CCH61188.1 - 0.072 13.0 7.2 0.2 11.6 7.2 1.9 1 0 0 1 1 1 0 Ribosomal L40e family Siva PF05458.12 CCH61188.1 - 0.11 12.1 6.7 0.061 13.0 2.4 2.1 2 0 0 2 2 2 0 Cd27 binding protein (Siva) zf-rbx1 PF12678.7 CCH61188.1 - 0.13 12.6 5.8 0.37 11.1 5.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Torus PF16131.5 CCH61188.1 - 0.2 12.3 7.2 0.25 12.1 5.6 2.1 1 1 0 1 1 1 0 Torus domain DZR PF12773.7 CCH61188.1 - 0.24 11.5 6.2 0.56 10.3 6.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 CCH61188.1 - 0.45 10.7 14.5 0.14 12.3 9.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING C1_2 PF03107.16 CCH61188.1 - 3.8 7.9 13.5 13 6.2 0.4 2.6 1 1 1 2 2 2 0 C1 domain Telomerase_RBD PF12009.8 CCH61189.1 - 1.2e-31 109.6 7.5 1.2e-31 109.6 7.5 2.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CCH61189.1 - 1.4e-10 41.0 9.7 2.2e-07 30.6 0.1 3.6 3 2 1 5 5 5 2 Reverse transcriptase (RNA-dependent DNA polymerase) Vps8 PF12816.7 CCH61190.1 - 8.6e-36 123.3 5.9 8.6e-36 123.3 5.9 2.3 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CCH61190.1 - 0.0034 17.2 28.5 0.17 11.7 0.3 5.6 5 1 0 5 5 5 3 Region in Clathrin and VPS zf-RING_5 PF14634.6 CCH61190.1 - 0.0095 15.9 3.6 0.0095 15.9 3.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CCH61190.1 - 0.011 15.5 3.5 0.027 14.2 3.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 CCH61190.1 - 0.018 14.9 3.3 0.064 13.1 3.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH61190.1 - 0.11 12.4 1.6 0.32 10.9 1.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FerA PF08165.11 CCH61190.1 - 0.14 12.1 1.0 1.7 8.7 1.0 3.0 1 0 0 1 1 1 0 FerA (NUC095) domain zf-RING_UBOX PF13445.6 CCH61190.1 - 0.72 9.9 3.3 2 8.5 3.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 CCH61190.1 - 2 8.7 13.7 0.028 14.7 2.8 2.9 3 0 0 3 3 3 0 RING-H2 zinc finger domain B-block_TFIIIC PF04182.12 CCH61191.1 - 8.1e-16 58.0 0.8 2.6e-15 56.3 0.0 2.4 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 CCH61191.1 - 0.017 14.7 0.0 0.051 13.1 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PheRS_DBD1 PF18552.1 CCH61191.1 - 0.099 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 PheRS DNA binding domain 1 Presenilin PF01080.17 CCH61191.1 - 0.17 10.6 2.9 0.28 9.9 2.9 1.4 1 0 0 1 1 1 0 Presenilin MarR_2 PF12802.7 CCH61191.1 - 0.19 11.7 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 MarR family N6-adenineMlase PF10237.9 CCH61192.1 - 7.2e-57 191.7 0.1 1.1e-56 191.0 0.1 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Ribosomal_L7Ae PF01248.26 CCH61193.1 - 4.2e-23 80.9 0.3 8.7e-23 79.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CCH61193.1 - 0.0072 16.4 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.16 CCH61194.1 - 1.1e-61 208.1 0.2 6.7e-61 205.5 0.2 2.3 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCH61194.1 - 4.8e-45 154.0 0.0 3.9e-37 128.1 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 CCH61195.1 - 9e-59 198.9 7.0 1.5e-58 198.2 7.0 1.3 1 0 0 1 1 1 1 Major intrinsic protein Nnf1 PF03980.14 CCH61196.1 - 2.8e-17 63.1 1.2 2.8e-17 63.1 1.2 1.8 2 0 0 2 2 2 1 Nnf1 UPF0242 PF06785.11 CCH61196.1 - 0.0059 16.7 0.9 0.0075 16.4 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus CcdA PF07362.12 CCH61196.1 - 0.041 14.3 0.4 0.36 11.3 0.1 2.4 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DUF2884 PF11101.8 CCH61196.1 - 0.064 12.7 2.8 1.1 8.7 1.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Pup PF05639.11 CCH61196.1 - 0.079 13.9 1.2 6.7 7.7 0.3 2.5 2 0 0 2 2 2 0 Pup-like protein bZIP_1 PF00170.21 CCH61196.1 - 8 6.6 9.8 0.89 9.7 1.6 2.8 3 0 0 3 3 3 0 bZIP transcription factor MIP PF00230.20 CCH61197.1 - 1.5e-73 247.3 5.3 2.6e-73 246.5 5.3 1.4 1 0 0 1 1 1 1 Major intrinsic protein Autophagy_act_C PF03987.15 CCH61198.1 - 2.2e-09 37.8 2.0 3.2e-09 37.2 0.5 2.0 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.6 CCH61199.1 - 9.9e-34 115.6 0.0 1.7e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CCH61199.1 - 7.4e-10 39.2 7.9 7.4e-10 39.2 7.9 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CCH61199.1 - 7.3e-08 32.8 8.6 7.3e-08 32.8 8.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CCH61199.1 - 1.1e-06 28.6 3.7 1.1e-06 28.6 3.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CCH61199.1 - 0.00078 19.3 4.2 0.0051 16.7 1.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 CCH61199.1 - 0.025 14.5 0.3 0.045 13.6 0.3 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Fer4_9 PF13187.6 CCH61199.1 - 0.029 14.5 7.6 0.029 14.5 7.6 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CCH61199.1 - 0.13 12.9 12.6 0.084 13.5 9.1 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain SHR-BD PF06650.12 CCH61200.1 - 2.6e-52 177.9 6.1 8.1e-50 169.7 0.8 3.8 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 CCH61200.1 - 3.3e-40 138.4 9.5 3.3e-40 138.4 9.5 4.0 4 1 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 CCH61200.1 - 1.5e-29 103.1 1.0 2.2e-27 96.0 0.0 4.1 3 1 1 4 4 4 1 Repeating coiled region of VPS13 Chorein_N PF12624.7 CCH61200.1 - 5e-24 84.7 0.1 2.5e-23 82.4 0.1 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CCH61200.1 - 7.9e-24 84.4 1.7 1.8e-23 83.2 0.1 2.4 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Ecm29 PF13001.7 CCH61201.1 - 4.2e-148 494.1 0.1 4.2e-148 494.1 0.1 4.4 4 0 0 4 4 4 2 Proteasome stabiliser HEAT PF02985.22 CCH61201.1 - 4.1e-15 54.6 3.1 0.29 11.5 0.0 9.7 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 CCH61201.1 - 4e-08 33.8 3.2 0.017 15.7 0.0 6.7 4 3 2 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CCH61201.1 - 0.00014 21.5 9.2 0.037 13.6 0.0 5.4 6 0 0 6 6 6 2 CLASP N terminal ParcG PF10274.9 CCH61201.1 - 0.0025 18.0 0.6 0.16 12.1 0.0 4.3 3 1 2 5 5 5 1 Parkin co-regulated protein RTP1_C1 PF10363.9 CCH61201.1 - 0.0046 17.1 0.0 2.5 8.3 0.0 4.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CCH61201.1 - 0.013 16.0 0.0 67 4.1 0.0 5.0 4 0 0 4 4 4 0 HEAT-like repeat L27 PF02828.16 CCH61201.1 - 0.12 12.1 0.1 0.99 9.2 0.0 2.6 2 0 0 2 2 2 0 L27 domain WSC PF01822.19 CCH61202.1 - 4.6e-10 39.6 15.9 4.6e-10 39.6 15.9 2.6 2 0 0 2 2 2 1 WSC domain AAA PF00004.29 CCH61203.1 - 4e-93 308.8 0.0 3.1e-47 160.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH61203.1 - 4.2e-22 77.7 0.1 2.9e-10 39.8 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCH61203.1 - 4.5e-15 55.7 0.0 1.1e-07 31.7 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCH61203.1 - 3e-13 50.5 0.9 9.1e-05 22.9 0.0 4.0 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CCH61203.1 - 5.8e-10 39.6 0.4 0.019 15.3 0.0 4.7 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 CCH61203.1 - 8.2e-10 39.1 0.0 0.00095 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCH61203.1 - 1.6e-09 38.1 0.0 0.00049 20.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CCH61203.1 - 1.9e-09 37.6 0.2 0.0008 19.4 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 CCH61203.1 - 7.9e-09 35.4 0.1 0.00084 19.3 0.0 2.9 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CCH61203.1 - 1.7e-08 34.1 0.0 0.00061 19.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CCH61203.1 - 2e-08 34.9 0.1 0.00077 20.0 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CCH61203.1 - 1.8e-07 31.3 0.0 0.038 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCH61203.1 - 4e-07 30.4 0.0 0.034 14.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 CCH61203.1 - 4.2e-07 30.6 0.0 0.017 15.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 CCH61203.1 - 1.2e-06 28.0 0.0 0.046 13.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Rad17 PF03215.15 CCH61203.1 - 2.2e-06 27.8 0.0 0.0097 15.8 0.0 2.7 2 0 0 2 2 2 2 Rad17 P-loop domain IstB_IS21 PF01695.17 CCH61203.1 - 3.2e-06 27.0 0.1 0.047 13.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCH61203.1 - 3.4e-06 26.6 0.1 0.051 12.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 CCH61203.1 - 6.4e-06 26.4 0.0 0.0003 21.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.6 CCH61203.1 - 7.2e-06 26.3 0.0 0.073 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CCH61203.1 - 9.5e-06 25.5 0.0 0.07 13.0 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 CCH61203.1 - 1.5e-05 24.5 0.0 2.5 7.5 0.0 3.8 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 CCH61203.1 - 2.8e-05 24.6 0.8 0.15 12.5 0.1 3.9 3 1 0 3 3 2 1 AAA domain TsaE PF02367.17 CCH61203.1 - 6.1e-05 23.0 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CCH61203.1 - 7.8e-05 22.3 0.0 0.45 10.0 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region NACHT PF05729.12 CCH61203.1 - 8.1e-05 22.6 0.1 0.62 10.0 0.0 3.1 3 0 0 3 3 2 2 NACHT domain SKI PF01202.22 CCH61203.1 - 0.00017 21.7 0.3 0.22 11.6 0.0 3.1 3 0 0 3 3 2 1 Shikimate kinase Sigma54_activat PF00158.26 CCH61203.1 - 0.00037 20.2 0.0 0.29 10.8 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CCH61203.1 - 0.00042 20.1 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CCH61203.1 - 0.00049 19.3 0.0 0.15 11.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 CCH61203.1 - 0.00051 19.7 0.2 2 8.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CCH61203.1 - 0.0006 19.8 0.0 2.4 8.0 0.0 3.6 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CCH61203.1 - 0.00095 18.9 0.0 0.9 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CCH61203.1 - 0.00096 19.3 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 CCH61203.1 - 0.0011 18.2 0.0 1.1 8.4 0.0 2.9 3 0 0 3 3 2 1 NB-ARC domain CPT PF07931.12 CCH61203.1 - 0.0017 18.2 0.0 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CCH61203.1 - 0.0018 17.7 0.0 1.5 8.1 0.0 3.1 3 0 0 3 3 3 1 KaiC Hydin_ADK PF17213.3 CCH61203.1 - 0.0024 18.2 3.0 0.81 9.9 0.0 3.3 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain Parvo_NS1 PF01057.17 CCH61203.1 - 0.0028 16.8 0.0 2 7.4 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 CCH61203.1 - 0.0066 16.2 0.1 0.47 10.2 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_19 PF13245.6 CCH61203.1 - 0.015 15.6 0.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CCH61203.1 - 0.019 14.7 0.0 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CCH61203.1 - 0.023 14.1 0.1 3 7.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.16 CCH61203.1 - 0.025 13.5 0.0 5.4 5.8 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase MCM PF00493.23 CCH61203.1 - 0.035 13.2 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain NTPase_1 PF03266.15 CCH61203.1 - 0.036 14.0 0.0 13 5.6 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 CCH61203.1 - 0.053 13.3 11.0 0.49 10.1 0.0 3.7 3 1 0 3 3 2 0 AAA domain FeoB_N PF02421.18 CCH61203.1 - 0.062 12.8 0.1 2.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Endonuc-BglII PF09195.11 CCH61203.1 - 0.065 13.1 3.4 1.7 8.5 0.2 2.5 2 0 0 2 2 2 0 Restriction endonuclease BglII RsgA_GTPase PF03193.16 CCH61203.1 - 0.071 13.0 0.0 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 CCH61203.1 - 0.089 12.9 0.2 3 8.0 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 CCH61203.1 - 0.097 12.1 0.0 21 4.4 0.0 2.8 2 1 1 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 CCH61203.1 - 0.17 11.6 0.0 16 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 CCH61203.1 - 0.28 10.6 0.6 23 4.3 0.0 2.7 3 0 0 3 3 2 0 Isopentenyl transferase AAA_23 PF13476.6 CCH61203.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.8 3 1 0 3 3 2 0 AAA domain DUF2456 PF10445.9 CCH61204.1 - 2.8e-20 72.2 3.6 5.8e-20 71.2 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) V_ATPase_I PF01496.19 CCH61204.1 - 4 5.2 19.5 3.3 5.5 0.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 CCH61205.1 - 0.41 9.1 29.6 0.65 8.4 29.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Creatinase_N_2 PF16189.5 CCH61207.1 - 1.2e-43 149.0 0.2 3.3e-43 147.6 0.2 1.8 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CCH61207.1 - 8.2e-40 136.7 0.0 1.3e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CCH61207.1 - 1.9e-20 72.7 1.3 9.8e-20 70.4 1.5 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CCH61207.1 - 6.4e-09 36.6 0.0 8e-08 33.0 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DUF3896 PF13035.6 CCH61207.1 - 0.43 10.8 6.7 17 5.7 0.4 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3896) MFS_1 PF07690.16 CCH61208.1 - 3.9e-42 144.4 28.5 3.9e-42 144.4 28.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH61208.1 - 8.8e-14 51.2 10.2 2.3e-13 49.8 10.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CCH61208.1 - 0.00015 20.3 2.0 0.00026 19.6 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M56 PF05569.11 CCH61208.1 - 0.079 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Macoilin PF09726.9 CCH61208.1 - 2.2 6.7 6.7 3 6.3 6.7 1.1 1 0 0 1 1 1 0 Macoilin family Fe-S_biosyn PF01521.20 CCH61209.1 - 1.2e-18 67.3 0.0 3e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NPR3 PF03666.13 CCH61210.1 - 2.6e-164 547.4 12.7 2.6e-164 547.4 12.7 3.3 3 0 0 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Enolase_C PF00113.22 CCH61211.1 - 2.6e-140 466.8 0.0 3.4e-140 466.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CCH61211.1 - 9.5e-55 184.3 0.1 1.5e-54 183.7 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CCH61211.1 - 8e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like Septin PF00735.18 CCH61212.1 - 2.2e-100 335.6 2.4 2.2e-100 335.6 2.4 2.0 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 CCH61212.1 - 3.1e-05 23.9 3.5 0.00024 21.0 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 CCH61212.1 - 0.00016 22.2 3.8 0.0082 16.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 CCH61212.1 - 0.00017 21.2 6.4 0.00017 21.2 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCH61212.1 - 0.00048 20.2 0.8 0.00098 19.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCH61212.1 - 0.0015 18.8 0.3 0.0086 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCH61212.1 - 0.0018 18.7 0.0 0.022 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 CCH61212.1 - 0.0036 17.5 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CCH61212.1 - 0.012 15.0 0.0 0.012 15.0 0.0 2.0 2 0 0 2 2 2 0 AIG1 family Exonuc_VII_L PF02601.15 CCH61212.1 - 0.022 14.4 7.3 0.032 13.8 7.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 CCH61212.1 - 0.029 13.0 9.9 0.046 12.3 9.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_29 PF13555.6 CCH61212.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF883 PF05957.13 CCH61212.1 - 0.26 11.9 5.3 0.53 10.9 5.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Sds3 PF08598.11 CCH61212.1 - 1.2 9.0 14.8 3 7.8 14.8 1.6 1 0 0 1 1 1 0 Sds3-like DUF3987 PF13148.6 CCH61212.1 - 3.8 6.4 6.8 18 4.2 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3987) RasGEF PF00617.19 CCH61213.1 - 3e-53 180.6 6.0 3.1e-53 180.6 0.3 3.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CCH61213.1 - 1.8e-19 69.9 0.5 1.8e-19 69.9 0.5 4.2 5 0 0 5 5 5 1 RasGEF N-terminal motif SH3_9 PF14604.6 CCH61213.1 - 1.6e-07 31.1 0.0 8.1e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CCH61213.1 - 2e-06 27.3 0.0 5.7e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CCH61213.1 - 9.5e-06 25.2 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UQ_con PF00179.26 CCH61214.1 - 7.8e-36 122.8 0.8 8.3e-36 122.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CCH61214.1 - 0.0091 15.9 1.0 0.048 13.5 0.5 2.1 1 1 1 2 2 2 1 UEV domain PALP PF00291.25 CCH61215.1 - 5.6e-63 213.1 0.0 7.2e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CCH61215.1 - 3.1e-15 56.4 0.1 6.5e-08 32.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain GAD PF02938.14 CCH61215.1 - 0.002 18.3 0.1 2.5 8.4 0.1 3.2 3 0 0 3 3 3 2 GAD domain GHMP_kinases_C PF08544.13 CCH61215.1 - 0.0067 16.8 0.0 0.028 14.8 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal ALAD PF00490.21 CCH61216.1 - 2.1e-119 398.4 0.0 2.6e-119 398.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HSP70 PF00012.20 CCH61217.1 - 5e-262 870.4 8.4 5.6e-262 870.3 8.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH61217.1 - 5.4e-18 64.9 0.2 1.3e-16 60.3 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 CCH61217.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCH61217.1 - 0.0084 16.5 1.2 14 6.2 0.0 3.6 3 1 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 CCH61217.1 - 0.021 13.8 0.2 0.095 11.7 0.1 1.9 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain S-AdoMet_synt_M PF02772.16 CCH61217.1 - 0.049 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain Hydantoinase_A PF01968.18 CCH61217.1 - 0.085 12.1 0.1 0.27 10.5 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase GARP PF16731.5 CCH61217.1 - 0.7 9.5 9.1 1.1 8.9 5.0 2.2 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma PMBR PF09373.10 CCH61217.1 - 1.5 9.1 4.5 2.8 8.2 0.0 3.1 4 0 0 4 4 4 0 Pseudomurein-binding repeat SWI-SNF_Ssr4 PF08549.10 CCH61217.1 - 3.4 6.2 9.3 18 3.8 0.1 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) UPF0121 PF03661.13 CCH61218.1 - 2.3e-29 102.5 13.9 2.8e-29 102.2 13.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_12 PF13424.6 CCH61219.1 - 6.3e-09 36.0 0.2 0.00023 21.4 0.0 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCH61219.1 - 6.7e-07 28.9 2.2 0.00026 20.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCH61219.1 - 3.3e-06 26.7 5.4 6.1e-06 25.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCH61219.1 - 4.1e-06 26.6 0.1 4.1e-06 26.6 0.1 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCH61219.1 - 5.8e-05 22.7 2.3 6.7e-05 22.5 0.3 2.2 2 0 0 2 2 2 1 TPR repeat SHNi-TPR PF10516.9 CCH61219.1 - 0.0005 19.5 0.3 0.0011 18.4 0.3 1.5 1 0 0 1 1 1 1 SHNi-TPR TPR_7 PF13176.6 CCH61219.1 - 0.0046 16.9 2.9 0.0053 16.7 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat SDA1 PF05285.12 CCH61219.1 - 0.045 13.2 14.7 0.065 12.6 14.7 1.3 1 0 0 1 1 1 0 SDA1 TPR_14 PF13428.6 CCH61219.1 - 0.12 13.3 0.7 0.7 10.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Presenilin PF01080.17 CCH61219.1 - 1.8 7.2 3.3 2.4 6.8 3.3 1.2 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 CCH61219.1 - 5.6 7.6 10.9 19 5.9 6.4 2.4 1 1 1 2 2 2 0 RPA43 OB domain in RNA Pol I 3Beta_HSD PF01073.19 CCH61220.1 - 6e-85 284.6 0.0 7.3e-85 284.4 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCH61220.1 - 1.3e-29 103.4 0.0 1.7e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCH61220.1 - 8.9e-19 68.1 0.0 5.9e-18 65.4 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CCH61220.1 - 2.5e-12 46.5 0.0 5e-11 42.3 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CCH61220.1 - 1.4e-09 37.5 0.0 2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CCH61220.1 - 6.5e-06 26.2 0.0 9.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CCH61220.1 - 8.2e-06 25.2 0.0 5.3e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CCH61220.1 - 0.039 13.9 0.0 0.46 10.4 0.0 2.2 1 1 0 1 1 1 0 KR domain DUP PF00674.18 CCH61221.1 - 7.8e-20 70.9 0.1 1.5e-19 70.0 0.1 1.4 1 0 0 1 1 1 1 DUP family PMI_typeI PF01238.21 CCH61222.1 - 1.6e-157 524.5 0.1 1.9e-157 524.3 0.1 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CCH61222.1 - 3.1e-05 23.9 0.0 0.009 15.9 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.11 CCH61222.1 - 0.0037 16.9 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain SEN1_N PF12726.7 CCH61222.1 - 0.22 9.7 0.0 0.31 9.2 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal DUF5314 PF17241.2 CCH61223.1 - 7.3e-10 38.8 3.5 9.2e-10 38.5 3.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5314) GN3L_Grn1 PF08701.11 CCH61224.1 - 3.8e-22 78.2 14.5 3.8e-22 78.2 14.5 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CCH61224.1 - 3.5e-17 62.5 0.3 1.6e-13 50.7 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH61224.1 - 2.2e-08 33.8 0.1 1.5e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCH61224.1 - 0.00068 19.6 1.6 0.009 15.9 0.4 2.7 1 1 1 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CCH61224.1 - 0.0013 18.8 7.9 0.68 10.0 0.1 3.9 2 2 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 CCH61224.1 - 0.0024 17.5 0.0 0.18 11.3 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CCH61224.1 - 0.016 14.2 0.1 0.042 12.8 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CCH61224.1 - 0.082 13.3 0.8 5.1 7.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 CCH61224.1 - 0.21 12.2 1.6 0.91 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain CAP_GLY PF01302.25 CCH61225.1 - 1.7e-12 47.2 0.2 3.1e-12 46.3 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 CCH61225.1 - 2.6e-11 43.6 39.7 0.0016 18.8 4.4 6.3 4 1 3 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCH61225.1 - 1.2e-08 34.6 28.8 7e-05 22.5 7.0 4.9 3 2 0 4 4 4 2 Leucine rich repeat Pentapeptide_4 PF13599.6 CCH61225.1 - 0.0053 16.9 1.1 0.4 10.9 0.2 3.0 1 1 0 2 2 2 1 Pentapeptide repeats (9 copies) LRR_1 PF00560.33 CCH61225.1 - 0.0098 16.3 26.9 15 6.6 0.1 8.3 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 CCH61225.1 - 0.034 14.2 34.9 0.084 13.0 0.2 7.8 8 0 0 8 8 8 0 Leucine Rich repeat LRR_9 PF14580.6 CCH61225.1 - 0.042 13.3 14.4 0.018 14.5 3.9 3.6 1 1 1 2 2 2 0 Leucine-rich repeat PTPA PF03095.15 CCH61226.1 - 1.4e-100 336.6 0.0 1.8e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PEPCK_ATP PF01293.20 CCH61227.1 - 1e-215 716.8 0.0 1.2e-215 716.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CCH61227.1 - 0.21 11.7 0.0 0.39 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 CCH61229.1 - 8e-22 77.7 21.4 8e-22 77.7 21.4 17.9 4 3 9 17 17 17 9 TPR/MLP1/MLP2-like protein DAO PF01266.24 CCH61231.1 - 2e-46 159.2 0.0 7.2e-46 157.4 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CCH61231.1 - 4.9e-39 133.1 0.0 8.4e-39 132.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CCH61231.1 - 2.9e-09 36.5 0.0 6.8e-09 35.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CCH61231.1 - 7.8e-06 25.5 0.7 0.0012 18.3 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CCH61231.1 - 0.00039 19.2 0.2 0.00072 18.4 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CCH61231.1 - 0.00045 19.4 0.5 0.0063 15.6 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CCH61231.1 - 0.00095 18.5 0.9 0.0043 16.3 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 CCH61231.1 - 0.0087 15.5 0.3 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CCH61231.1 - 0.0092 16.2 0.4 0.028 14.7 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CCH61231.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CCH61231.1 - 0.014 14.6 0.0 1.7 7.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CCH61231.1 - 0.014 14.6 0.1 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 CCH61231.1 - 0.051 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCH61231.1 - 0.095 13.3 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CCH61231.1 - 0.17 11.7 1.0 0.58 10.0 1.0 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UCH PF00443.29 CCH61232.1 - 1.6e-61 208.0 0.4 1.6e-61 208.0 0.4 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH61232.1 - 4.3e-20 72.6 0.5 4.3e-20 72.6 0.5 3.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCH61232.1 - 2.8e-05 24.6 0.0 8.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain A2L_zn_ribbon PF08792.10 CCH61232.1 - 0.07 12.9 1.1 0.38 10.5 0.5 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Pur_ac_phosph_N PF16656.5 CCH61232.1 - 4.3 8.0 9.2 17 6.1 2.4 2.8 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Myb_DNA-binding PF00249.31 CCH61233.1 - 2.4e-28 98.0 7.6 1e-12 48.0 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH61233.1 - 1.7e-27 95.4 1.6 3e-10 40.2 0.6 3.9 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CCH61233.1 - 0.00059 19.8 0.0 1.6 8.8 0.0 3.0 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 CCH61233.1 - 0.0077 16.4 0.0 8 6.7 0.0 3.4 3 1 1 4 4 4 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 CCH61233.1 - 0.059 13.3 0.0 2.4 8.1 0.0 3.1 2 0 0 2 2 2 0 Myb DNA-binding like Rap1_C PF11626.8 CCH61233.1 - 0.1 12.7 0.2 9.6 6.4 0.1 2.7 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Coa1 PF08695.10 CCH61234.1 - 1e-38 131.7 0.0 1.3e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SKG6 PF08693.10 CCH61235.1 - 8.9e-05 21.8 0.1 0.00017 20.9 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NifW PF03206.14 CCH61235.1 - 0.1 13.1 0.8 1.2 9.6 0.1 2.9 3 0 0 3 3 3 0 Nitrogen fixation protein NifW FH2 PF02181.23 CCH61236.1 - 2.4e-69 234.3 7.8 2.4e-69 234.3 7.8 2.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Lant_dehydr_C PF14028.6 CCH61236.1 - 0.11 12.0 0.8 0.17 11.4 0.2 1.5 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF1515 PF07439.11 CCH61236.1 - 1.1 9.4 7.9 0.18 11.9 2.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) EF-hand_2 PF09068.11 CCH61236.1 - 2.5 8.3 7.5 0.72 10.0 0.2 3.5 2 1 0 2 2 2 0 EF hand Thiolase_N PF00108.23 CCH61237.1 - 1.2e-78 264.1 0.0 1.6e-78 263.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCH61237.1 - 1.5e-49 166.8 0.3 3.1e-49 165.7 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCH61237.1 - 0.00065 19.3 0.2 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF4945 PF16303.5 CCH61238.1 - 0.012 15.6 0.6 0.03 14.3 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4945) RWD PF05773.22 CCH61238.1 - 0.048 13.9 3.9 0.11 12.8 3.9 1.8 1 1 0 1 1 1 0 RWD domain LAP1C PF05609.12 CCH61238.1 - 0.74 8.8 16.4 0.93 8.5 16.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF1460 PF07313.12 CCH61239.1 - 0.021 14.2 3.2 0.076 12.4 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) vATP-synt_E PF01991.18 CCH61240.1 - 1.1e-60 204.5 15.9 1.3e-60 204.3 15.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.11 CCH61240.1 - 1.8 7.8 12.2 0.49 9.7 9.4 1.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Folliculin PF11704.8 CCH61240.1 - 8.7 6.2 9.2 16 5.3 8.8 1.7 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CorA PF01544.18 CCH61241.1 - 0.0014 18.0 9.3 0.0049 16.2 9.3 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Casein_kappa PF00997.18 CCH61241.1 - 0.61 10.2 3.3 2.3 8.3 3.3 2.0 1 1 0 1 1 1 0 Kappa casein RNase_P_Rpp14 PF01900.19 CCH61243.1 - 5.1e-34 116.6 0.1 6.7e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family RRM_4 PF10598.9 CCH61243.1 - 0.056 13.8 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 RNA recognition motif of the spliceosomal PrP8 Fungal_trans PF04082.18 CCH61244.1 - 8.7e-35 120.0 4.0 1.8e-34 119.0 4.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH61244.1 - 4.1e-07 30.0 11.3 6.7e-07 29.3 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.17 CCH61245.1 - 3.5e-09 36.9 0.0 8.6e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain DTHCT PF08070.11 CCH61245.1 - 0.025 15.3 4.1 0.084 13.6 4.2 1.8 1 1 0 1 1 1 0 DTHCT (NUC029) region Mis12 PF05859.12 CCH61246.1 - 1.2e-28 99.8 1.6 1.2e-28 99.8 1.6 1.9 1 1 1 2 2 2 1 Mis12 protein RNA_pol_Rpb1_5 PF04998.17 CCH61247.1 - 4.4e-96 321.4 1.6 4.4e-96 321.4 1.6 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCH61247.1 - 1.8e-68 230.0 0.2 6.7e-68 228.1 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCH61247.1 - 2.9e-39 134.5 0.3 1.2e-37 129.2 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CCH61247.1 - 1.2e-25 90.5 4.4 1.2e-25 90.5 4.4 3.4 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CCH61247.1 - 1e-23 83.4 2.9 2.9e-23 81.9 0.0 3.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 TFIIA PF03153.13 CCH61247.1 - 0.0003 20.9 11.7 0.00067 19.8 11.7 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 CCH61247.1 - 3.2 8.5 17.5 1.5e+02 3.1 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) GTP_EFTU PF00009.27 CCH61248.1 - 5.4e-34 117.4 2.2 7.7e-34 116.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCH61248.1 - 1.8e-20 73.0 0.0 5.4e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CCH61248.1 - 2.4e-16 59.9 1.1 2.1e-09 37.6 0.0 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH61248.1 - 8.8e-08 32.2 0.3 2e-06 27.9 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCH61248.1 - 5e-06 26.3 1.3 3.2e-05 23.7 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu domain 4 Roc PF08477.13 CCH61248.1 - 0.00032 20.9 0.0 0.00032 20.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CCH61248.1 - 0.017 14.6 0.0 0.13 11.8 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 CCH61249.1 - 1.3e-38 131.2 0.0 2.6e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CCH61249.1 - 3.7e-21 74.9 0.1 6.9e-21 74.1 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CCH61249.1 - 3.4e-19 69.0 0.1 8.4e-19 67.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH61249.1 - 6.9e-09 35.4 0.1 1.8e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCH61249.1 - 0.011 15.8 0.3 6.5 6.8 0.3 2.5 1 1 1 2 2 2 0 Dynamin family MeaB PF03308.16 CCH61249.1 - 0.012 14.6 0.2 0.025 13.6 0.2 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CCH61249.1 - 0.026 14.8 0.1 13 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain Arf PF00025.21 CCH61249.1 - 0.077 12.5 0.2 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCH61249.1 - 0.16 11.8 0.2 4.1 7.3 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase Sugar_tr PF00083.24 CCH61250.1 - 1.7e-157 524.9 37.7 2e-157 524.7 37.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH61250.1 - 6.9e-33 114.0 38.7 4.6e-31 108.0 26.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH61250.1 - 0.00028 19.4 4.7 0.00049 18.6 4.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PRP21_like_P PF12230.8 CCH61251.1 - 3.8e-27 95.6 7.1 3.8e-27 95.6 7.1 1.6 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Pro_isomerase PF00160.21 CCH61252.1 - 7.4e-43 146.6 0.0 1.2e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 CCH61252.1 - 1.4e-09 37.4 5.0 3.5e-09 36.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCH61252.1 - 2.6e-08 33.4 2.7 1.9e-07 30.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCH61252.1 - 0.00022 21.2 0.5 0.00058 19.9 0.0 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCH61252.1 - 0.0013 18.4 0.7 0.04 13.6 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 CCH61252.1 - 0.0013 19.2 2.2 0.0049 17.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCH61252.1 - 0.0024 17.1 0.1 0.0035 16.6 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH61252.1 - 0.0026 18.4 0.2 0.038 14.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CCH61252.1 - 0.0038 17.3 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCH61252.1 - 0.0048 17.1 0.5 0.015 15.6 0.3 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCH61252.1 - 0.034 14.5 0.1 1.2 9.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCH61252.1 - 0.055 14.1 0.1 0.61 10.8 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCH61252.1 - 0.19 12.2 0.5 1.3 9.5 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.21 CCH61253.1 - 5e-16 59.2 0.2 1.3e-15 57.9 0.1 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tubulin PF00091.25 CCH61254.1 - 1.2e-66 224.7 0.0 2.4e-66 223.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCH61254.1 - 4.4e-10 39.8 1.7 4.4e-10 39.8 1.7 2.4 2 1 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCH61254.1 - 8.3e-05 22.9 0.2 0.00019 21.7 0.2 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF2013 PF09431.10 CCH61255.1 - 8.7e-41 139.3 13.7 8.7e-41 139.3 13.7 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2013) Sel1 PF08238.12 CCH61256.1 - 5.4e-18 65.0 16.8 2.7e-06 27.8 1.2 9.6 10 0 0 10 10 10 4 Sel1 repeat TPR_1 PF00515.28 CCH61256.1 - 3.6e-07 29.7 5.7 0.48 10.3 0.1 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCH61256.1 - 8.7e-05 22.4 2.0 1.2 9.5 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH61256.1 - 0.00065 19.5 0.6 15 5.9 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCH61256.1 - 0.04 14.1 14.0 1.2 9.6 0.0 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCH61256.1 - 0.071 13.6 0.2 39 4.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ENTH PF01417.20 CCH61257.1 - 2.4e-35 121.3 0.0 4.9e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 ENTH domain DNA_ligase_A_M PF01068.21 CCH61258.1 - 6.2e-63 212.1 0.0 1e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCH61258.1 - 3.3e-44 151.3 0.1 6.3e-44 150.3 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CCH61258.1 - 4e-25 88.3 0.0 1.6e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region TMEM51 PF15345.6 CCH61258.1 - 0.022 14.6 4.5 0.059 13.2 3.0 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 DNA_ligase_OB_2 PF14743.6 CCH61258.1 - 0.076 13.0 0.6 11 6.2 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain BORG_CEP PF14957.6 CCH61258.1 - 0.17 13.1 1.8 0.4 11.8 1.8 1.6 1 0 0 1 1 1 0 Cdc42 effector zf-RanBP PF00641.18 CCH61259.1 - 1.2e-21 75.7 10.9 2.2e-10 39.7 1.0 3.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CCH61259.1 - 3.1e-06 26.9 0.0 0.0005 19.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Utp14 PF04615.13 CCH61259.1 - 1.8 7.0 12.3 2.6 6.5 12.3 1.2 1 0 0 1 1 1 0 Utp14 protein DZR PF12773.7 CCH61259.1 - 5.3 7.2 9.4 12 6.0 3.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon NOA36 PF06524.12 CCH61259.1 - 5.6 6.2 17.1 0.72 9.1 11.5 2.1 2 0 0 2 2 2 0 NOA36 protein Rubredoxin PF00301.20 CCH61259.1 - 9.3 6.4 8.9 1.2 9.3 0.7 2.9 3 0 0 3 3 3 0 Rubredoxin POC1 PF10450.9 CCH61260.1 - 4.5e-63 212.8 5.0 8.6e-45 152.8 1.0 2.0 1 1 1 2 2 2 2 POC1 chaperone Nop PF01798.18 CCH61261.1 - 3.3e-84 282.0 0.1 3.3e-84 282.0 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCH61261.1 - 3.3e-20 72.2 0.8 3.3e-20 72.2 0.8 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 CCH61261.1 - 0.19 12.0 20.1 0.32 11.2 20.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 CCH61261.1 - 1.7 8.7 55.0 3.5 7.6 55.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MCM_bind PF09739.9 CCH61261.1 - 2.2 6.6 21.5 3.2 6.1 21.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 CCH61261.1 - 2.9 7.6 32.5 4.7 6.9 32.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Response_reg PF00072.24 CCH61263.1 - 7.8e-26 90.4 1.0 1.8e-25 89.3 1.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CCH61263.1 - 7.4e-25 87.6 0.4 2.4e-19 69.9 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CCH61263.1 - 1.1e-10 41.4 0.1 3.1e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CCH61263.1 - 0.087 13.2 0.0 0.68 10.4 0.0 2.3 2 0 0 2 2 2 0 HAMP domain ubiquitin PF00240.23 CCH61264.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CCH61264.1 - 1.2e-30 105.1 11.3 1.8e-30 104.5 11.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CCH61264.1 - 1.9e-16 59.6 0.7 3e-16 59.0 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCH61264.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CCH61264.1 - 0.0037 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCH61264.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCH61264.1 - 0.0048 17.0 0.1 0.011 15.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CCH61264.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CCH61264.1 - 0.025 15.2 0.1 0.033 14.8 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCH61264.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain EMP24_GP25L PF01105.24 CCH61265.1 - 2.7e-32 112.2 0.3 3.4e-32 111.9 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4298 PF14131.6 CCH61265.1 - 0.051 13.5 0.3 0.089 12.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) FUN14 PF04930.15 CCH61266.1 - 0.00097 19.5 0.7 0.0019 18.5 0.7 1.6 1 0 0 1 1 1 1 FUN14 family DUF4462 PF14692.6 CCH61266.1 - 0.7 9.4 3.1 0.47 10.0 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) B56 PF01603.20 CCH61267.1 - 2.7e-158 527.3 12.6 5.9e-158 526.2 12.6 1.5 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CCH61267.1 - 0.7 9.8 4.6 2.2 8.2 2.0 2.9 2 1 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Spo7 PF03907.13 CCH61268.1 - 4.3e-65 219.3 6.7 5.4e-65 219.0 6.7 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF2208 PF09973.9 CCH61268.1 - 0.0012 18.5 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) DUF3169 PF11368.8 CCH61268.1 - 0.0063 16.1 1.4 0.42 10.1 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3169) Pox_EPC_I2-L1 PF12575.8 CCH61268.1 - 3.4 8.0 5.0 11 6.3 0.1 2.9 2 1 1 3 3 3 0 Poxvirus entry protein complex L1 and I2 MDM10 PF12519.8 CCH61269.1 - 1.1e-28 100.3 19.6 3.1e-24 85.7 8.3 2.6 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 DUF5371 PF17341.2 CCH61269.1 - 0.19 11.9 1.1 9.5 6.5 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5371) DUF775 PF05603.12 CCH61270.1 - 5.6e-60 202.3 0.1 6.7e-60 202.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA-synt_1c PF00749.21 CCH61271.1 - 4.5e-107 357.6 0.0 5.7e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain RuvB_C PF05491.13 CCH61271.1 - 0.035 14.0 0.1 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain AAA_23 PF13476.6 CCH61272.1 - 1.3e-20 74.8 6.6 1.3e-20 74.8 6.6 5.7 2 2 1 3 3 1 1 AAA domain SMC_N PF02463.19 CCH61272.1 - 5.4e-14 52.2 39.8 3.2e-13 49.6 39.8 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH61272.1 - 1.5e-05 24.6 0.0 3.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCH61272.1 - 2.3e-05 24.3 32.3 2.3e-05 24.3 32.3 3.9 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 CCH61272.1 - 0.015 15.1 0.1 0.015 15.1 0.1 4.0 3 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CCH61272.1 - 0.032 14.1 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CCH61272.1 - 0.052 13.1 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCH61272.1 - 0.084 13.4 0.0 0.084 13.4 0.0 4.7 3 2 0 3 3 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 CCH61272.1 - 0.11 11.9 3.4 2.2 7.6 0.0 3.3 2 1 0 3 3 3 0 FtsK/SpoIIIE family AAA_33 PF13671.6 CCH61272.1 - 0.16 12.2 1.0 0.71 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Abi_C PF14355.6 CCH61272.1 - 1.9 8.6 5.8 6.3 7.0 0.1 4.3 4 0 0 4 4 4 0 Abortive infection C-terminus CAF-1_p150 PF11600.8 CCH61273.1 - 0.0092 15.7 35.5 0.0092 15.7 35.5 3.2 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SKIP_SNW PF02731.15 CCH61274.1 - 1.7e-46 157.8 9.1 1.7e-46 157.8 9.1 1.7 2 0 0 2 2 2 1 SKIP/SNW domain DUF4675 PF15720.5 CCH61274.1 - 0.11 12.2 1.3 0.22 11.3 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4675) IFT20 PF14931.6 CCH61274.1 - 3.7 7.7 15.8 0.17 12.1 9.0 2.3 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 SNARE PF05739.19 CCH61275.1 - 7.7e-08 32.2 0.5 1.7e-07 31.1 0.5 1.6 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 CCH61275.1 - 8.1e-05 22.5 2.1 0.00011 22.0 2.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sds3 PF08598.11 CCH61276.1 - 4e-44 151.2 0.0 4e-44 151.2 0.0 2.0 2 0 0 2 2 2 1 Sds3-like Cys_Met_Meta_PP PF01053.20 CCH61277.1 - 2.1e-145 484.1 0.0 2.4e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CCH61277.1 - 3.2e-06 25.9 0.0 4.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CCH61277.1 - 0.0099 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCH61277.1 - 0.016 14.2 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V DUF805 PF05656.14 CCH61278.1 - 0.12 12.8 1.8 0.26 11.7 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF3899 PF13038.6 CCH61278.1 - 3.8 8.1 9.0 0.092 13.3 1.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Exo_endo_phos PF03372.23 CCH61279.1 - 0.00011 21.8 0.0 0.00024 20.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5529 PF17669.1 CCH61279.1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5529) HEAT PF02985.22 CCH61280.1 - 2.3e-33 111.3 13.1 0.049 13.9 0.0 12.5 13 0 0 13 13 13 9 HEAT repeat HEAT_2 PF13646.6 CCH61280.1 - 9.7e-28 96.4 0.6 4.1e-07 30.3 0.0 7.4 3 2 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 CCH61280.1 - 7.4e-12 45.7 6.3 0.014 15.9 0.0 6.9 4 1 4 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CCH61280.1 - 3.6e-10 40.1 1.9 6.3 7.4 0.0 8.3 8 0 0 8 8 8 3 HEAT-like repeat Cnd1 PF12717.7 CCH61280.1 - 3.3e-05 24.0 14.5 0.0093 16.0 2.2 5.6 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 API5 PF05918.11 CCH61280.1 - 0.021 13.6 13.7 0.14 11.0 2.1 4.5 4 2 1 5 5 5 0 Apoptosis inhibitory protein 5 (API5) Arm PF00514.23 CCH61280.1 - 0.099 12.7 1.8 20 5.4 0.0 4.6 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat ADP_PFK_GK PF04587.15 CCH61280.1 - 0.11 11.1 0.3 0.2 10.2 0.3 1.3 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region VPDSG-CTERM PF18205.1 CCH61281.1 - 0.16 11.8 1.0 0.25 11.2 1.0 1.3 1 0 0 1 1 1 0 VPDSG-CTERM motif Pkinase PF00069.25 CCH61282.1 - 9e-62 208.8 0.0 1.8e-61 207.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61282.1 - 6.9e-22 78.0 0.0 1.1e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH61282.1 - 2.5e-06 27.0 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCH61282.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CCH61282.1 - 0.0054 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCH61282.1 - 0.015 14.1 0.2 0.039 12.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 CCH61282.1 - 0.064 12.9 1.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PAS_8 PF13188.7 CCH61282.1 - 0.071 13.2 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 CCH61282.1 - 0.14 12.1 0.0 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 PAS fold Med15_fungi PF05397.12 CCH61284.1 - 3.9e-33 114.1 6.8 3.9e-33 114.1 6.8 7.9 7 1 0 7 7 7 1 Mediator complex subunit 15 PMT PF02366.18 CCH61285.1 - 6.9e-81 271.4 18.0 6.9e-81 271.4 18.0 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCH61285.1 - 6.1e-59 199.0 12.1 6.1e-59 199.0 12.1 2.3 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCH61285.1 - 6.3e-21 75.1 0.2 1.2e-20 74.2 0.2 1.3 1 0 0 1 1 1 1 MIR domain LDB19 PF13002.7 CCH61286.1 - 4.9e-63 212.3 0.1 7.1e-63 211.8 0.1 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 CCH61286.1 - 0.0057 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain RasGEF PF00617.19 CCH61287.1 - 4.1e-40 137.8 4.1 4.1e-40 137.8 4.1 3.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CCH61287.1 - 2.5e-14 53.4 3.4 2.5e-14 53.4 3.4 4.4 4 0 0 4 4 4 1 RasGEF N-terminal motif Androgen_recep PF02166.16 CCH61287.1 - 0.56 9.0 5.9 1.1 8.0 5.9 1.4 1 0 0 1 1 1 0 Androgen receptor Ribosomal_L28e PF01778.17 CCH61288.1 - 6.4e-41 139.7 3.4 6.4e-41 139.7 3.4 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CCH61288.1 - 6.3e-31 106.9 18.7 6.3e-31 106.9 18.7 2.5 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CCH61288.1 - 0.00014 21.4 19.1 0.00016 21.1 19.1 1.1 1 0 0 1 1 1 1 BUD22 Ribosomal_L24e PF01246.20 CCH61288.1 - 0.0083 16.3 0.2 0.021 15.1 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e PYC_OADA PF02436.18 CCH61288.1 - 0.1 12.3 1.7 0.16 11.7 1.7 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain Cypo_polyhedrin PF05865.11 CCH61290.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.3 1 1 0 1 1 1 0 Cypovirus polyhedrin protein rve PF00665.26 CCH61291.1 - 0.0011 19.1 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain FRB_dom PF08771.11 CCH61292.1 - 0.013 15.9 0.5 0.087 13.2 0.2 2.0 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain DUF5049 PF16468.5 CCH61292.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) Aldedh PF00171.22 CCH61293.1 - 8.6e-15 54.2 1.8 1.9e-09 36.6 0.1 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 CCH61293.1 - 0.066 12.3 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Saw1 PF11561.8 CCH61294.1 - 2.4e-86 289.3 8.0 2.7e-86 289.1 8.0 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Myosin_head PF00063.21 CCH61296.1 - 4.7e-276 917.4 17.6 9.7e-276 916.4 17.6 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CCH61296.1 - 9.3e-27 93.3 2.4 9.3e-27 93.3 2.4 3.5 4 0 0 4 4 4 1 DIL domain IQ PF00612.27 CCH61296.1 - 2.1e-10 39.5 19.2 6.4e-05 22.4 0.3 6.5 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_16 PF13191.6 CCH61296.1 - 0.0054 17.1 1.8 0.029 14.8 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Myosin_N PF02736.19 CCH61296.1 - 0.0081 16.0 0.1 0.022 14.6 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CCH61296.1 - 0.011 16.0 2.2 0.019 15.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CCH61296.1 - 0.12 12.9 0.0 0.12 12.9 0.0 3.4 3 1 0 3 3 3 0 ABC transporter DUF4398 PF14346.6 CCH61296.1 - 3.7 8.3 9.4 11 6.7 9.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Synaptobrevin PF00957.21 CCH61297.1 - 1.8e-31 107.8 2.0 2e-31 107.6 2.0 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.12 CCH61297.1 - 0.16 12.1 2.3 0.23 11.6 2.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DNApol_Exo PF18136.1 CCH61299.1 - 1.4e-96 322.9 0.3 1.4e-96 322.9 0.3 1.8 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CCH61299.1 - 3.9e-57 194.0 0.0 2.3e-56 191.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family A Nif11 PF07862.11 CCH61299.1 - 8.1 6.8 7.0 6.9 7.1 0.1 3.7 4 0 0 4 4 4 0 Nif11 domain Pkinase PF00069.25 CCH61300.1 - 2.2e-53 181.3 6.7 8.9e-48 162.9 1.5 2.0 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61300.1 - 9.4e-16 57.9 1.1 1e-11 44.6 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CCH61300.1 - 7.4e-05 22.8 0.0 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCH61300.1 - 0.011 14.5 0.3 0.038 12.8 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase Kdo PF06293.14 CCH61300.1 - 0.035 13.5 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 CCH61301.1 - 1.2e-08 35.0 7.6 2e-08 34.2 7.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCH61301.1 - 1.9e-06 27.9 8.1 3.6e-06 26.9 8.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Metallophos PF00149.28 CCH61302.1 - 1.7e-06 28.7 10.7 7.9e-06 26.5 10.7 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DnaJ-X PF14308.6 CCH61303.1 - 3.7e-55 186.7 8.8 3.7e-55 186.7 8.8 2.2 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCH61303.1 - 1.3e-26 92.5 1.6 4.1e-26 90.9 1.6 1.9 1 0 0 1 1 1 1 DnaJ domain HLH PF00010.26 CCH61303.1 - 0.076 13.0 0.7 0.21 11.6 0.7 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 CCH61304.1 - 2.6e-28 99.0 42.5 2.6e-28 99.0 42.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH61304.1 - 6.8e-05 21.5 6.1 0.00011 20.8 6.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CCH61304.1 - 0.0019 16.5 10.7 0.0059 15.0 10.6 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4690 PF15756.5 CCH61304.1 - 0.27 11.9 0.4 0.7 10.5 0.4 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage SGL PF08450.12 CCH61305.1 - 1.6e-48 165.4 0.0 2e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CCH61305.1 - 0.061 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Arylesterase MFS_1 PF07690.16 CCH61306.1 - 8.6e-37 126.9 32.9 8.6e-37 126.9 32.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCH61306.1 - 6.3e-06 24.9 2.8 1.2e-05 23.9 2.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CCH61306.1 - 1.9 6.6 18.3 0.14 10.5 10.7 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RVT_1 PF00078.27 CCH61308.1 - 6.3e-15 55.3 0.0 9.7e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A2B PF12384.8 CCH61308.1 - 3.9e-12 46.1 0.0 6.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.11 CCH61308.1 - 1.5e-06 28.0 0.2 4.1e-06 26.6 0.1 1.7 1 1 1 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CCH61308.1 - 9.8e-05 22.8 0.0 0.00017 22.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCH61308.1 - 0.00029 21.4 0.0 0.00051 20.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.17 CCH61309.1 - 1.4e-13 50.9 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4939 PF16297.5 CCH61309.1 - 0.012 15.4 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Cbl_N2 PF02761.14 CCH61309.1 - 0.09 13.5 0.5 0.51 11.1 0.2 2.2 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain CYSTM PF12734.7 CCH61310.1 - 4.4e-08 33.3 42.4 0.0002 21.6 42.4 3.1 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance DUF4452 PF14618.6 CCH61310.1 - 0.77 9.6 5.5 0.99 9.3 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) DAHP_synth_1 PF00793.20 CCH61311.1 - 6e-104 346.8 0.0 7e-104 346.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family HALZ PF02183.18 CCH61312.1 - 0.16 12.2 16.7 0.24 11.7 2.4 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper LMBR1 PF04791.16 CCH61312.1 - 3.9 6.3 8.7 6.5 5.5 8.7 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 CCH61312.1 - 7.3 7.1 19.5 5.1 7.6 0.5 4.7 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) UCH PF00443.29 CCH61313.1 - 1.9e-41 142.3 0.3 1.9e-41 142.3 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCH61313.1 - 1e-21 77.0 4.8 1e-21 77.0 4.8 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CCH61313.1 - 2.5e-14 53.6 9.9 5.2e-14 52.5 3.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CCH61313.1 - 3.9e-13 49.0 0.1 9.9e-09 34.9 0.7 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 CCH61313.1 - 2.4e-06 27.2 10.8 8.5e-05 22.2 5.4 3.3 2 1 0 2 2 2 2 Variant UBP zinc finger ECH_2 PF16113.5 CCH61314.1 - 1.9e-89 300.5 0.0 2.3e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CCH61314.1 - 6e-26 91.3 0.0 8.9e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SeleniumBinding PF11524.8 CCH61314.1 - 0.014 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Selenium binding protein DUF2683 PF10884.8 CCH61314.1 - 0.033 14.5 0.7 20 5.5 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2683) Pkinase PF00069.25 CCH61315.1 - 3.8e-39 134.6 0.0 7.2e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61315.1 - 1.2e-23 83.7 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCH61315.1 - 0.00089 18.7 0.0 0.0052 16.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH61315.1 - 0.0054 16.7 0.0 0.71 9.7 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCH61315.1 - 0.028 13.4 0.0 0.028 13.4 0.0 3.1 3 0 0 3 3 3 0 Haspin like kinase domain CaM-KIIN PF15170.6 CCH61315.1 - 0.083 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor Pkinase_fungal PF17667.1 CCH61315.1 - 0.11 11.2 0.1 0.31 9.8 0.1 1.7 1 0 0 1 1 1 0 Fungal protein kinase ORC2 PF04084.14 CCH61316.1 - 1.6e-107 359.3 0.9 2e-107 358.9 0.9 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 tRNA-synt_2 PF00152.20 CCH61317.1 - 2.9e-75 253.3 0.6 3.9e-75 252.8 0.6 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCH61317.1 - 3.4e-13 49.4 0.3 2.9e-12 46.4 0.3 2.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCH61317.1 - 2.9e-07 30.2 0.0 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) E1-E2_ATPase PF00122.20 CCH61318.1 - 1.3e-34 119.3 11.2 2.4e-31 108.6 0.1 4.4 4 1 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCH61318.1 - 7.5e-31 107.2 0.7 7.5e-31 107.2 0.7 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCH61318.1 - 8.5e-22 78.5 0.0 2.7e-20 73.6 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH61318.1 - 2e-17 63.1 0.6 7.7e-17 61.2 0.6 2.0 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CCH61318.1 - 5.3e-13 48.5 1.1 8.1e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCH61318.1 - 0.0018 18.0 0.5 0.0018 18.0 0.5 3.5 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Asp PF00026.23 CCH61319.1 - 7.4e-68 229.3 13.0 2.1e-57 195.0 5.6 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH61319.1 - 5.2e-12 46.3 3.9 4.7e-06 26.9 0.1 2.7 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal BCSC_C PF05420.11 CCH61319.1 - 0.00048 19.4 0.3 0.001 18.3 0.3 1.5 1 0 0 1 1 1 1 Cellulose synthase operon protein C C-terminus (BCSC_C) PAPS_reduct PF01507.19 CCH61322.1 - 8e-34 117.2 0.0 5.3e-33 114.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sdh5 PF03937.16 CCH61323.1 - 6.8e-27 93.2 0.6 1.1e-26 92.6 0.6 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase DUF2606 PF10794.9 CCH61324.1 - 0.088 12.6 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) PRP3 PF08572.10 CCH61325.1 - 7.1e-57 192.7 17.1 9.7e-57 192.3 17.1 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CCH61325.1 - 2.9e-29 102.0 0.1 2.9e-29 102.0 0.1 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1115) TRAPP PF04051.16 CCH61327.1 - 4.6e-46 156.2 0.0 5.8e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.25 CCH61328.1 - 5.6e-14 52.4 0.0 8.4e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCH61328.1 - 1.7e-07 31.2 0.1 2.3e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCH61328.1 - 5.9e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CCH61328.1 - 8.3e-05 22.9 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCH61328.1 - 0.0014 18.2 0.7 0.0017 17.8 0.3 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CCH61328.1 - 0.0098 16.0 0.4 0.02 14.9 0.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Metallophos_2 PF12850.7 CCH61329.1 - 4.4e-09 36.7 0.0 9.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Autophagy_C PF10381.9 CCH61329.1 - 0.0081 15.7 0.4 0.015 14.8 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Brr6_like_C_C PF10104.9 CCH61329.1 - 0.18 11.6 1.6 0.37 10.6 1.6 1.5 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain ABC2_membrane_3 PF12698.7 CCH61329.1 - 0.91 8.6 8.5 1.2 8.2 8.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein GREB1 PF15782.5 CCH61329.1 - 4.5 4.3 15.1 5.4 4.0 15.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer tRNA-synt_2b PF00587.25 CCH61330.1 - 2e-24 86.5 0.5 7.3e-24 84.7 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CCH61330.1 - 0.00015 22.0 7.0 0.00036 20.7 7.0 1.7 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Lip_prot_lig_C PF10437.9 CCH61330.1 - 0.13 12.2 2.8 1.4 8.9 0.6 2.9 2 1 1 3 3 3 0 Bacterial lipoate protein ligase C-terminus Occludin_ELL PF07303.13 CCH61330.1 - 0.15 12.8 3.4 0.4 11.4 2.7 2.1 1 1 0 1 1 1 0 Occludin homology domain Syntaxin-6_N PF09177.11 CCH61330.1 - 0.17 12.4 5.1 0.79 10.3 5.1 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 CCH61330.1 - 0.22 11.5 5.7 0.67 10.0 0.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 CCH61330.1 - 0.34 10.9 8.0 0.66 10.0 8.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PI_PP_I PF18363.1 CCH61330.1 - 0.47 10.7 6.0 0.85 9.8 0.9 2.6 1 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain HIP1_clath_bdg PF16515.5 CCH61330.1 - 2.2 9.0 4.9 7.7 7.2 2.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dad3 PF08656.10 CCH61330.1 - 2.3 8.3 6.7 2.6 8.2 0.7 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad3 FapA PF03961.13 CCH61330.1 - 3.8 6.0 9.3 2.8 6.5 5.3 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A FliD_N PF02465.18 CCH61330.1 - 9.8 6.9 8.0 24 5.7 0.2 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_L27e PF01777.18 CCH61331.1 - 1.2e-35 121.7 7.5 1.7e-35 121.2 7.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CCH61331.1 - 0.00069 19.5 1.6 0.0012 18.7 1.6 1.5 1 0 0 1 1 1 1 KOW motif Mito_carr PF00153.27 CCH61332.1 - 1.6e-09 37.5 0.0 0.0059 16.5 0.0 3.9 4 1 0 4 4 4 3 Mitochondrial carrier protein Dpy-30 PF05186.13 CCH61333.1 - 2.7e-11 42.9 0.1 4.2e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif DAO PF01266.24 CCH61334.1 - 1.7e-68 231.8 0.0 1.2e-67 229.0 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH61334.1 - 1.5e-05 25.1 0.1 3.5e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCH61334.1 - 0.00068 19.0 0.0 0.16 11.2 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCH61334.1 - 0.0057 15.9 0.5 0.021 14.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family MCRA PF06100.11 CCH61334.1 - 0.0097 14.7 0.1 0.019 13.7 0.0 1.6 2 0 0 2 2 2 1 MCRA family Sacchrp_dh_NADP PF03435.18 CCH61334.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 CCH61334.1 - 0.045 13.7 0.1 0.55 10.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pex14_N PF04695.13 CCH61334.1 - 4 8.1 16.5 14 6.3 10.9 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 CCH61335.1 - 5.3e-66 222.7 0.4 9.6e-66 221.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61335.1 - 8.8e-31 107.1 0.0 1.3e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH61335.1 - 2.5e-06 27.0 0.0 6.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CCH61335.1 - 0.00067 19.4 0.4 1.5 8.4 0.0 2.7 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Sod_Fe_C PF02777.18 CCH61336.1 - 2.3e-27 95.1 0.7 4.5e-27 94.2 0.7 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CCH61336.1 - 1.1e-20 73.8 0.5 4.6e-20 71.9 0.5 2.0 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain p450 PF00067.22 CCH61337.1 - 7e-107 358.0 0.0 8e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ERGIC_N PF13850.6 CCH61337.1 - 0.14 12.5 0.1 0.4 11.1 0.1 1.8 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C2H2 PF00096.26 CCH61338.1 - 0.00049 20.4 3.3 0.00049 20.4 3.3 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH61338.1 - 0.004 17.5 0.5 0.004 17.5 0.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH61338.1 - 0.0064 17.2 1.6 0.0064 17.2 1.6 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2HE PF16278.5 CCH61338.1 - 0.057 13.9 0.0 0.057 13.9 0.0 4.1 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3660 PF12398.8 CCH61338.1 - 0.17 11.9 0.4 0.17 11.9 0.4 2.2 2 0 0 2 2 2 0 Receptor serine/threonine kinase zf-Di19 PF05605.12 CCH61338.1 - 1.9 8.9 6.8 1.2 9.5 4.4 2.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Elf1 PF05129.13 CCH61338.1 - 7 6.8 6.9 26 4.9 3.4 3.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DHHC PF01529.20 CCH61339.1 - 8.1e-28 97.2 8.4 8.1e-28 97.2 8.4 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF3723 PF12520.8 CCH61339.1 - 0.023 13.4 0.1 0.033 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) MARVEL PF01284.23 CCH61339.1 - 0.8 9.7 6.9 0.076 13.0 1.8 1.9 2 0 0 2 2 2 0 Membrane-associating domain SdpI PF13630.6 CCH61339.1 - 1.3 9.2 6.4 1.5 9.0 2.0 2.4 2 1 0 2 2 2 0 SdpI/YhfL protein family A_deaminase PF00962.22 CCH61340.1 - 6e-131 436.6 0.0 8.9e-131 436.1 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase MSC PF09402.10 CCH61341.1 - 3.9e-58 197.5 0.1 3.9e-58 197.5 0.1 2.5 3 0 0 3 3 3 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CCH61341.1 - 1.6e-08 34.1 0.9 5e-08 32.5 0.9 1.9 1 0 0 1 1 1 1 HeH/LEM domain Endonuc-dimeris PF09124.10 CCH61341.1 - 0.00025 21.2 0.5 0.00092 19.3 0.5 2.0 1 0 0 1 1 1 1 T4 recombination endonuclease VII, dimerisation RNA_pol_A_CTD PF03118.15 CCH61341.1 - 0.037 13.8 3.2 0.052 13.3 0.5 2.5 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain YicC_N PF03755.13 CCH61341.1 - 0.06 13.8 0.5 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 YicC-like family, N-terminal region HECT PF00632.25 CCH61342.1 - 3.9e-90 302.4 0.1 1.4e-89 300.6 0.1 2.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CCH61342.1 - 3.9e-78 263.4 14.4 3.9e-78 263.4 14.4 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CCH61342.1 - 1.2e-49 169.3 0.5 1.2e-49 169.3 0.5 4.1 5 1 1 6 6 6 1 Domain of Unknown Function (DUF913) UBM PF14377.6 CCH61342.1 - 1.3e-14 53.0 6.6 6.2e-07 28.7 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin binding region Ndc1_Nup PF09531.10 CCH61343.1 - 5.6e-24 84.8 30.3 8e-18 64.5 28.1 3.4 2 1 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Na_H_Exchanger PF00999.21 CCH61344.1 - 6.7e-69 232.5 34.5 8.6e-69 232.1 34.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Wzy_C PF04932.15 CCH61344.1 - 2.5 7.7 0.0 2.5 7.7 0.0 3.3 3 2 0 3 3 3 0 O-Antigen ligase Guanylate_kin PF00625.21 CCH61345.1 - 6.4e-69 231.3 0.0 7e-69 231.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CCH61345.1 - 1.3e-06 28.7 0.0 4.6e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH61345.1 - 4.4e-06 27.2 0.2 1.4e-05 25.6 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CCH61345.1 - 1.6e-05 24.7 0.5 0.00066 19.4 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH61345.1 - 0.0001 22.8 0.0 0.00018 22.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCH61345.1 - 0.00014 22.1 0.0 0.00055 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCH61345.1 - 0.00026 21.0 0.1 0.0045 17.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CCH61345.1 - 0.00083 19.9 0.0 0.00098 19.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA PF00004.29 CCH61345.1 - 0.00098 19.6 0.0 0.0032 17.9 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CCH61345.1 - 0.0012 18.5 0.4 0.026 14.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CCH61345.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCH61345.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 CCH61345.1 - 0.0027 18.1 0.0 0.0046 17.3 0.0 1.7 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CCH61345.1 - 0.0028 17.7 0.0 0.0078 16.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH61345.1 - 0.0031 17.2 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCH61345.1 - 0.0048 16.4 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CCH61345.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain T2SSE PF00437.20 CCH61345.1 - 0.022 13.8 0.4 0.099 11.7 0.1 1.9 1 1 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 CCH61345.1 - 0.03 14.7 0.1 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCH61345.1 - 0.033 14.1 0.0 0.067 13.1 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 CCH61345.1 - 0.036 14.1 0.1 0.12 12.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 CCH61345.1 - 0.041 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 CCH61345.1 - 0.073 12.7 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 CCH61345.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Roc PF08477.13 CCH61345.1 - 0.085 13.1 0.0 0.76 10.0 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase KAP_NTPase PF07693.14 CCH61345.1 - 0.091 12.0 0.0 0.13 11.5 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 CCH61345.1 - 0.095 13.2 1.7 0.25 11.8 1.7 1.9 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CCH61345.1 - 0.1 12.6 0.3 0.69 9.9 0.0 2.2 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 CCH61345.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCH61345.1 - 0.16 11.5 0.1 0.52 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ubiquitin PF00240.23 CCH61346.1 - 0.0082 15.9 0.2 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 CCH61346.1 - 0.046 14.3 0.1 0.3 11.7 0.0 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain PRIMA1 PF16101.5 CCH61346.1 - 5.3 7.1 8.7 7.2 6.7 7.1 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 AhpC-TSA PF00578.21 CCH61347.1 - 2.2e-35 121.2 0.0 6e-35 119.9 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CCH61347.1 - 2.9e-16 59.5 0.0 5.2e-16 58.7 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CCH61347.1 - 1.5e-08 34.4 0.2 2.6e-08 33.5 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CCH61347.1 - 0.024 14.5 0.2 0.046 13.6 0.2 1.4 1 0 0 1 1 1 0 SCO1/SenC sCache_like PF16736.5 CCH61348.1 - 4.6 7.4 12.0 1.6 8.8 3.1 3.1 2 1 0 2 2 2 0 Single Cache-like Lipase_GDSL PF00657.22 CCH61349.1 - 0.0033 17.4 0.7 0.48 10.4 0.6 2.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nrf1_DNA-bind PF10491.9 CCH61349.1 - 0.041 13.6 0.2 0.089 12.5 0.2 1.5 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Med19 PF10278.9 CCH61349.1 - 2.1 8.2 10.4 5 7.0 10.4 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SPT16 PF08644.11 CCH61349.1 - 3.2 7.9 7.8 3.1 8.0 0.3 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Homeodomain PF00046.29 CCH61350.1 - 1.2e-16 60.2 4.8 2.7e-16 59.1 4.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCH61350.1 - 0.002 18.0 1.4 0.014 15.3 1.4 2.4 1 1 0 1 1 1 1 Homeobox KN domain NAD_Gly3P_dh_N PF01210.23 CCH61350.1 - 0.15 12.0 0.6 0.29 11.1 0.6 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribosomal_L4 PF00573.22 CCH61351.1 - 6.2e-36 123.9 0.6 1.7e-33 115.9 0.2 2.2 1 1 1 2 2 2 2 Ribosomal protein L4/L1 family U3_assoc_6 PF08640.11 CCH61352.1 - 9.2e-31 105.8 4.0 9.2e-31 105.8 4.0 3.2 3 1 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CCH61352.1 - 3.9e-05 23.0 5.1 0.046 12.9 0.6 2.6 1 1 0 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.14 CCH61352.1 - 0.13 12.2 5.3 2.7 7.9 4.0 3.3 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) ZZ PF00569.17 CCH61353.1 - 1.9e-16 59.6 8.3 3.3e-16 58.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CCH61353.1 - 6.3e-09 35.9 0.0 1.6e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 CCH61353.1 - 8.5e-07 29.2 0.2 8.5e-07 29.2 0.2 3.1 3 1 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 CCH61353.1 - 0.00025 21.2 1.0 0.0021 18.2 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain PRP38 PF03371.15 CCH61353.1 - 0.014 15.3 0.8 0.026 14.4 0.8 1.4 1 0 0 1 1 1 0 PRP38 family Methyltransf_4 PF02390.17 CCH61353.1 - 0.042 13.3 0.3 0.094 12.2 0.3 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF676 PF05057.14 CCH61354.1 - 9.2e-47 159.4 0.0 1.4e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CCH61354.1 - 2.1e-05 24.4 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 CCH61354.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Med13_N PF11597.8 CCH61355.1 - 1.3e-56 192.3 5.8 2.6e-56 191.3 5.8 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 CCH61355.1 - 1.5e-25 90.2 0.5 1.5e-19 70.5 0.1 4.3 3 2 2 5 5 5 2 Mediator complex subunit 13 C-terminal domain Pribosyltran PF00156.27 CCH61356.1 - 5e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCH61356.1 - 0.0043 16.5 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YfdX PF10938.8 CCH61356.1 - 0.13 12.2 0.0 4.6 7.2 0.0 2.1 2 0 0 2 2 2 0 YfdX protein DOT1 PF08123.13 CCH61357.1 - 6.3e-79 264.3 0.0 1.3e-78 263.3 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 2-Hacid_dh_C PF02826.19 CCH61357.1 - 0.17 11.3 0.0 10 5.4 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.18 CCH61359.1 - 2.2e-07 30.9 9.5 3.9e-07 30.1 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.20 CCH61360.1 - 2.9e-57 194.0 14.2 3.4e-57 193.7 14.2 1.0 1 0 0 1 1 1 1 Haemolysin-III related 7TMR-DISM_7TM PF07695.11 CCH61360.1 - 0.003 17.5 13.6 0.003 17.5 13.6 2.0 1 1 1 2 2 2 1 7TM diverse intracellular signalling DUF998 PF06197.13 CCH61360.1 - 0.12 11.9 2.2 6.9 6.2 2.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Cation_ATPase_C PF00689.21 CCH61360.1 - 0.56 9.9 9.9 1.3 8.7 5.5 2.5 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus TPP_enzyme_N PF02776.18 CCH61361.1 - 1.6e-31 109.2 0.0 2.7e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH61361.1 - 4e-27 94.6 0.0 1.5e-26 92.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCH61361.1 - 7.9e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CCH61361.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit PLA2_B PF01735.18 CCH61362.1 - 4.6e-218 724.5 1.5 6.6e-218 724.1 1.5 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCH61362.1 - 0.16 12.2 1.0 0.32 11.2 1.0 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Apt1 PF10351.9 CCH61362.1 - 4.1 6.2 7.4 6.6 5.5 7.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 CCH61362.1 - 6.9 5.6 14.8 15 4.5 14.8 1.5 1 0 0 1 1 1 0 Protein family FAM199X RTC PF01137.21 CCH61363.1 - 7.5e-45 152.8 0.0 9.5e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CCH61363.1 - 4.2e-27 94.7 0.0 6.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.24 CCH61364.1 - 3.1e-21 75.5 0.4 7.4e-21 74.2 0.1 1.9 2 0 0 2 2 2 1 PX domain Polyketide_cyc PF03364.20 CCH61365.1 - 3.2e-15 56.5 0.0 3.9e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CCH61365.1 - 0.03 14.6 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport CHCH PF06747.13 CCH61366.1 - 1.8e-05 24.8 3.9 2.6e-05 24.2 3.9 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 CCH61366.1 - 0.014 15.5 21.1 0.037 14.1 20.8 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) COX6B PF02297.17 CCH61366.1 - 0.22 11.8 2.2 0.33 11.2 2.2 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CCH61366.1 - 0.43 10.6 3.0 0.68 10.0 3.0 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2981 PF11200.8 CCH61367.1 - 0.33 10.7 2.5 0.27 10.9 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2981) Topoisom_I_N PF02919.15 CCH61368.1 - 1e-97 325.8 1.3 1e-97 325.8 1.3 3.5 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CCH61368.1 - 4.2e-97 324.0 0.6 4.2e-97 324.0 0.6 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 CCH61368.1 - 2.5e-32 110.6 0.4 2.5e-32 110.6 0.4 3.1 3 0 0 3 3 3 1 C-terminal topoisomerase domain GPW_gp25 PF04965.14 CCH61368.1 - 0.06 13.1 0.0 0.2 11.4 0.0 1.9 1 0 0 1 1 1 0 Gene 25-like lysozyme GREB1 PF15782.5 CCH61368.1 - 3.3 4.7 29.6 5.5 4.0 29.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RNA_pol_L_2 PF13656.6 CCH61369.1 - 2.7e-26 91.1 0.0 3.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCH61369.1 - 2.9e-09 36.2 0.0 4.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sin3a_C PF16879.5 CCH61370.1 - 8e-80 268.6 12.4 8e-80 268.6 12.4 4.7 4 1 1 5 5 5 1 C-terminal domain of Sin3a protein PAH PF02671.21 CCH61370.1 - 5.1e-44 148.2 14.7 1.9e-18 66.3 0.0 4.2 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CCH61370.1 - 2.5e-33 114.0 0.0 1e-32 112.0 0.0 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor Histone PF00125.24 CCH61371.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CCH61371.1 - 2e-13 49.8 0.3 4.1e-13 48.8 0.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CCH61371.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DAGK_cat PF00781.24 CCH61372.1 - 5.6e-27 93.8 0.0 8.8e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SDA1 PF05285.12 CCH61372.1 - 0.0047 16.4 17.9 0.0077 15.7 17.9 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 CCH61372.1 - 0.01 14.1 12.1 0.015 13.5 12.1 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 CCH61372.1 - 0.013 15.6 16.2 0.023 14.8 16.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FYDLN_acid PF09538.10 CCH61372.1 - 0.12 13.1 15.8 0.33 11.6 15.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 CCH61372.1 - 0.69 9.2 19.8 1.2 8.4 19.8 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4746 PF15928.5 CCH61372.1 - 0.71 9.2 4.3 1.5 8.2 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BUD22 PF09073.10 CCH61372.1 - 1 8.6 38.2 0.052 12.9 23.7 2.1 2 0 0 2 2 2 0 BUD22 DUF572 PF04502.13 CCH61372.1 - 5.2 6.6 17.7 0.055 13.1 8.6 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) DNA_pol_phi PF04931.13 CCH61372.1 - 5.4 5.0 21.4 7.8 4.5 21.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CCH61372.1 - 5.6 5.1 15.9 9.3 4.4 15.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ras PF00071.22 CCH61373.1 - 4.1e-57 192.3 0.3 4.8e-57 192.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH61373.1 - 1.7e-37 128.3 0.8 2.3e-37 127.9 0.2 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH61373.1 - 9.5e-16 57.7 0.6 1.1e-15 57.6 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCH61373.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCH61373.1 - 2e-05 24.6 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH61373.1 - 4.1e-05 23.5 0.0 0.06 13.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CCH61373.1 - 0.00014 21.3 0.1 0.00018 21.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCH61373.1 - 0.0011 18.6 0.1 0.0085 15.6 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 CCH61373.1 - 0.0019 18.2 0.4 0.0075 16.2 0.0 1.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CCH61373.1 - 0.0032 17.0 0.1 0.0046 16.5 0.1 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 CCH61373.1 - 0.0042 16.8 0.5 0.025 14.3 0.5 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CCH61373.1 - 0.006 16.9 0.0 0.015 15.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 CCH61373.1 - 0.015 15.1 0.1 0.021 14.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 CCH61373.1 - 0.021 13.7 0.1 0.033 13.0 0.1 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 CCH61373.1 - 0.04 14.3 0.0 0.062 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CCH61373.1 - 0.062 13.3 0.2 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CCH61373.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 CCH61373.1 - 0.1 11.7 0.5 0.14 11.3 0.5 1.5 1 1 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.6 CCH61373.1 - 0.67 9.6 6.1 12 5.5 6.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Cas_GSU0054 PF09609.10 CCH61374.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) SURF2 PF05477.11 CCH61374.1 - 1.4 8.5 12.2 2.1 8.0 12.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) YqfQ PF14181.6 CCH61374.1 - 3.3 7.9 4.8 5.5 7.2 4.8 1.3 1 0 0 1 1 1 0 YqfQ-like protein Rtt102p PF09510.10 CCH61375.1 - 0.16 12.2 6.2 0.11 12.7 3.9 1.8 1 1 0 1 1 1 0 Rtt102p-like transcription regulator protein Oxidored_FMN PF00724.20 CCH61376.1 - 1.1e-121 406.4 0.0 1.2e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Jag_N PF14804.6 CCH61376.1 - 0.16 12.3 0.1 0.53 10.7 0.2 1.7 2 0 0 2 2 2 0 Jag N-terminus SinI PF08671.10 CCH61376.1 - 0.31 10.9 2.5 0.92 9.4 0.3 2.8 2 1 0 2 2 2 0 Anti-repressor SinI RHD3 PF05879.12 CCH61377.1 - 4e-218 726.2 28.2 1.9e-217 724.0 28.2 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 CCH61377.1 - 0.00017 21.6 0.1 0.00055 20.0 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCH61377.1 - 0.0007 19.7 0.1 0.0007 19.7 0.1 2.7 3 0 0 3 3 3 1 Dynamin family AAA_28 PF13521.6 CCH61377.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Erf4 PF10256.9 CCH61377.1 - 1.2 9.3 5.5 0.47 10.6 0.5 2.9 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family IZUMO PF15005.6 CCH61377.1 - 4.5 7.8 7.0 1.9 9.0 1.1 3.0 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated DUF410 PF04190.13 CCH61378.1 - 5.8e-75 252.4 1.6 7e-75 252.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.28 CCH61379.1 - 9e-15 54.9 0.1 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain LEF-9 PF05094.12 CCH61379.1 - 0.086 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) PalH PF08733.10 CCH61380.1 - 6.1e-92 308.2 39.5 6.1e-92 308.2 39.5 1.7 2 0 0 2 2 2 1 PalH/RIM21 bZIP_1 PF00170.21 CCH61382.1 - 3.4e-10 39.9 10.3 9.4e-10 38.5 10.3 1.8 1 0 0 1 1 1 1 bZIP transcription factor LAGLIDADG_WhiA PF14527.6 CCH61382.1 - 0.081 13.0 0.9 0.18 11.9 0.9 1.6 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain bZIP_2 PF07716.15 CCH61382.1 - 0.64 10.1 9.8 1.7 8.8 9.8 1.8 1 0 0 1 1 1 0 Basic region leucine zipper DUF5122 PF17164.4 CCH61382.1 - 1.7 9.0 3.9 5.5 7.4 3.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller AAA_2 PF07724.14 CCH61383.1 - 9e-52 175.6 0.4 1e-48 165.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCH61383.1 - 1.4e-34 118.1 1.4 1.4e-34 118.1 1.4 3.0 2 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CCH61383.1 - 1.6e-26 92.1 0.2 1.6e-26 92.1 0.2 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CCH61383.1 - 5.9e-21 75.3 0.1 3.5e-10 40.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCH61383.1 - 5e-17 62.2 0.1 2e-12 47.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCH61383.1 - 2e-11 44.5 1.3 0.001 19.5 0.0 4.1 2 2 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 CCH61383.1 - 9.5e-08 31.9 0.1 6.3e-06 26.0 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CCH61383.1 - 1.7e-07 31.4 0.0 0.0023 18.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CCH61383.1 - 3e-07 30.8 0.0 0.04 14.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain TniB PF05621.11 CCH61383.1 - 1.9e-06 27.4 0.2 0.0011 18.4 0.0 3.9 3 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 CCH61383.1 - 4e-06 26.5 0.0 0.059 12.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CCH61383.1 - 8.6e-06 25.6 0.1 0.041 13.6 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 CCH61383.1 - 6.2e-05 22.4 0.0 0.0044 16.3 0.0 3.2 2 1 1 3 3 3 1 Zeta toxin DUF815 PF05673.13 CCH61383.1 - 6.9e-05 22.1 3.3 0.45 9.6 0.2 3.7 2 2 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 CCH61383.1 - 0.00014 21.8 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 CCH61383.1 - 0.00017 21.6 13.3 0.14 12.0 0.1 4.6 3 2 2 6 6 4 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CCH61383.1 - 0.00026 21.5 7.8 0.15 12.6 0.0 4.3 4 1 1 5 5 5 2 AAA domain AAA_30 PF13604.6 CCH61383.1 - 0.00031 20.5 0.3 1.7 8.3 0.0 3.3 3 1 0 3 3 3 2 AAA domain TsaE PF02367.17 CCH61383.1 - 0.00054 20.0 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CCH61383.1 - 0.00064 20.0 0.0 0.33 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 CCH61383.1 - 0.00097 18.9 0.0 0.72 9.6 0.0 2.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CCH61383.1 - 0.0012 18.5 0.0 0.19 11.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 CCH61383.1 - 0.0013 19.0 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CCH61383.1 - 0.002 18.5 0.1 3.2 8.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 CCH61383.1 - 0.0023 17.8 5.1 0.057 13.3 0.0 3.2 4 0 0 4 4 2 1 RsgA GTPase AAA_6 PF12774.7 CCH61383.1 - 0.0032 16.5 0.1 0.37 9.7 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region AAA_24 PF13479.6 CCH61383.1 - 0.0033 17.2 0.5 0.49 10.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCH61383.1 - 0.0042 17.6 7.0 0.32 11.5 0.0 3.8 3 2 0 3 3 2 1 ABC transporter SRP54 PF00448.22 CCH61383.1 - 0.009 15.7 0.0 1.6 8.4 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 CCH61383.1 - 0.011 15.1 0.0 1.2 8.5 0.0 3.0 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCH61383.1 - 0.013 15.9 0.7 17 5.7 0.2 3.9 2 2 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CCH61383.1 - 0.014 15.2 6.4 0.64 9.8 0.1 4.2 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Torsin PF06309.11 CCH61383.1 - 0.023 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.6 CCH61383.1 - 0.033 14.3 0.0 5 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CCH61383.1 - 0.035 13.5 0.2 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein MMR_HSR1 PF01926.23 CCH61383.1 - 0.036 14.1 1.1 2.5 8.2 0.0 3.4 3 2 0 3 3 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 CCH61383.1 - 0.047 12.7 0.8 0.2 10.7 0.8 2.1 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.11 CCH61383.1 - 0.049 13.5 0.1 0.91 9.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CCH61383.1 - 0.059 13.1 0.0 6.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ResIII PF04851.15 CCH61383.1 - 0.067 13.2 4.8 0.48 10.4 0.0 4.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CCH61383.1 - 0.098 12.2 0.0 6.1 6.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 CCH61383.1 - 0.25 11.8 30.3 0.14 12.6 0.6 3.9 3 1 0 3 3 2 0 AAA domain TPR_1 PF00515.28 CCH61384.1 - 1.3e-47 157.7 11.6 7.9e-09 35.0 0.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 CCH61384.1 - 5.3e-39 129.2 10.9 8.8e-07 28.6 0.1 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CCH61384.1 - 9.2e-37 124.8 16.0 1.6e-18 66.4 4.2 3.0 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 CCH61384.1 - 3.7e-26 90.5 14.4 1.1e-05 25.1 0.0 7.7 7 0 0 7 7 7 6 TPR repeat TPR_12 PF13424.6 CCH61384.1 - 5e-19 68.4 7.7 1.3e-05 25.3 0.2 6.5 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCH61384.1 - 8.3e-19 66.2 13.3 7.5e-06 25.8 0.1 9.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCH61384.1 - 6.6e-18 65.1 3.8 0.00024 21.7 0.0 6.6 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCH61384.1 - 6.8e-17 60.7 0.4 0.019 15.7 0.0 8.0 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCH61384.1 - 2.5e-16 58.4 4.4 0.024 14.7 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CCH61384.1 - 1.6e-14 54.1 8.9 0.034 14.7 0.0 7.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 CCH61384.1 - 2.1e-12 46.5 0.7 0.73 10.3 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCH61384.1 - 3.2e-08 33.6 0.0 0.0032 17.6 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCH61384.1 - 1.6e-07 31.0 6.8 0.031 14.2 0.1 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCH61384.1 - 2.6e-06 27.7 10.2 10 7.0 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH61384.1 - 0.00019 21.6 9.9 1.5 9.1 0.8 5.3 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 CCH61384.1 - 0.00053 18.9 6.5 0.0011 17.7 0.0 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) MIT PF04212.18 CCH61384.1 - 0.003 17.6 16.0 1.5 9.0 0.1 6.5 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain TPM_phosphatase PF04536.14 CCH61384.1 - 0.015 15.5 1.8 18 5.5 0.0 3.6 3 0 0 3 3 3 0 TPM domain RPN7 PF10602.9 CCH61384.1 - 0.017 14.9 14.3 1.6 8.4 0.0 5.8 2 2 0 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 CCH61384.1 - 0.11 11.9 6.5 28 4.3 0.0 5.3 7 0 0 7 7 7 0 SHNi-TPR DUF5113 PF17140.4 CCH61384.1 - 0.24 11.2 6.0 0.37 10.6 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) TPR_3 PF07720.12 CCH61384.1 - 0.35 10.9 10.7 7.3 6.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.15 CCH61384.1 - 0.94 9.6 0.0 0.94 9.6 0.0 4.5 4 1 2 6 6 6 0 MAS20 protein import receptor XPC-binding PF09280.11 CCH61384.1 - 1.3 8.8 9.5 0.31 10.8 1.7 2.9 2 1 0 2 2 2 0 XPC-binding domain Vta1_C PF18097.1 CCH61384.1 - 2.7 7.8 6.8 29 4.5 0.0 4.7 5 0 0 5 5 5 0 Vta1 C-terminal domain TPR_20 PF14561.6 CCH61384.1 - 5.5 7.4 10.2 18 5.8 0.1 4.6 5 3 2 7 7 4 0 Tetratricopeptide repeat SET PF00856.28 CCH61385.1 - 4.2e-17 63.1 0.0 9.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 SET domain Methyltransf_3 PF01596.17 CCH61385.1 - 0.0087 15.2 0.0 0.063 12.4 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase WD40 PF00400.32 CCH61386.1 - 2.2e-08 34.6 3.2 0.00092 20.0 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61386.1 - 6e-06 26.5 0.0 1.1 9.6 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCH61386.1 - 0.00061 19.2 2.4 0.077 12.3 0.2 3.0 1 1 2 3 3 3 3 WD40-like domain BBS2_Mid PF14783.6 CCH61386.1 - 0.003 17.6 0.2 0.86 9.7 0.0 3.4 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CPSF_A PF03178.15 CCH61386.1 - 0.016 14.6 0.2 3.4 6.9 0.1 2.8 1 1 1 3 3 3 0 CPSF A subunit region PHTB1_N PF14727.6 CCH61386.1 - 0.13 11.6 0.1 2.5 7.3 0.0 2.3 1 1 0 2 2 2 0 PTHB1 N-terminus Pex24p PF06398.11 CCH61387.1 - 2.4e-78 263.7 7.0 2.9e-78 263.4 7.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpr2 PF04032.16 CCH61388.1 - 1.6e-11 44.4 2.2 3.1e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain SIR2 PF02146.17 CCH61389.1 - 9.4e-36 123.4 0.0 5.1e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Sir2 family Pkinase PF00069.25 CCH61390.1 - 9.4e-77 257.9 0.1 1.4e-76 257.4 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 CCH61390.1 - 2.2e-54 182.9 0.6 2.8e-53 179.4 0.1 2.6 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 CCH61390.1 - 2e-37 128.9 0.0 3.5e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 CCH61390.1 - 2.4e-18 66.0 5.0 2.5e-18 65.9 1.5 2.4 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CCH61390.1 - 2.7e-10 40.1 0.0 4.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 CCH61390.1 - 0.00023 20.1 0.9 0.00034 19.6 0.9 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.22 CCH61390.1 - 0.00035 20.2 0.9 0.00075 19.1 0.9 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 CCH61390.1 - 0.0044 16.4 0.4 0.011 15.1 0.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCH61390.1 - 0.0075 15.3 1.0 0.014 14.3 0.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCH61390.1 - 0.04 13.8 0.4 0.15 12.0 0.3 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family LSM PF01423.22 CCH61391.1 - 2.7e-21 75.0 0.2 4e-21 74.5 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCH61391.1 - 0.0083 16.2 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Mitoc_mL59 PF18126.1 CCH61392.1 - 3.4e-26 92.1 0.3 3.4e-26 92.1 0.3 1.8 1 1 1 2 2 2 1 Mitochondrial ribosomal protein mL59 Prefoldin PF02996.17 CCH61393.1 - 2.4e-35 121.1 3.8 3.3e-35 120.6 3.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit SOGA PF11365.8 CCH61393.1 - 0.0064 17.6 4.2 1.1 10.5 0.3 2.4 2 0 0 2 2 2 2 Protein SOGA SNAD4 PF18750.1 CCH61393.1 - 0.068 13.3 0.1 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 CENP-F_leu_zip PF10473.9 CCH61393.1 - 0.61 10.1 10.4 3.4 7.7 1.4 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATP19 PF11022.8 CCH61394.1 - 3e-16 59.6 0.0 3.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Bmt2 PF11968.8 CCH61395.1 - 7.8e-73 245.0 3.3 7.8e-73 245.0 3.3 1.8 2 1 0 2 2 2 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CCH61395.1 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH61395.1 - 0.011 16.4 0.0 0.035 14.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CCH61395.1 - 0.017 15.8 1.2 0.037 14.8 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.18 CCH61395.1 - 0.026 14.0 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain DEAD PF00270.29 CCH61396.1 - 5.3e-36 124.0 0.0 1.4e-35 122.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61396.1 - 6.2e-30 103.8 0.4 4.4e-27 94.6 0.2 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCH61396.1 - 3.1e-07 30.6 0.0 3.1e-07 30.6 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit NACHT PF05729.12 CCH61396.1 - 0.013 15.5 0.0 0.099 12.6 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CCH61396.1 - 0.34 11.2 5.0 0.22 11.8 0.3 3.1 2 1 1 3 3 3 0 AAA domain CPSF100_C PF13299.6 CCH61396.1 - 1 9.5 10.6 0.5 10.5 6.7 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA PF00004.29 CCH61396.1 - 1.1 9.6 3.6 16 5.9 0.1 3.6 3 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) ADH_N PF08240.12 CCH61397.1 - 5.7e-29 100.2 0.4 1.4e-28 99.0 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH61397.1 - 1.5e-22 79.9 1.0 2.5e-22 79.2 1.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCH61397.1 - 4.9e-05 24.4 0.1 8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NqrM PF04400.13 CCH61397.1 - 4.1 7.2 6.6 0.36 10.6 0.4 2.3 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM ADH_N PF08240.12 CCH61398.1 - 2.7e-29 101.2 0.4 5.8e-29 100.2 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH61398.1 - 6.1e-23 81.2 0.5 1e-22 80.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCH61398.1 - 2.7e-05 25.3 0.0 5.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NqrM PF04400.13 CCH61398.1 - 2.6 7.9 6.9 0.2 11.4 0.5 2.3 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM Tetraspanin PF00335.20 CCH61399.1 - 0.033 13.9 0.2 0.033 13.9 0.2 1.9 1 1 1 2 2 2 0 Tetraspanin family D5_N PF08706.11 CCH61400.1 - 0.1 12.9 2.6 0.15 12.3 2.6 1.3 1 0 0 1 1 1 0 D5 N terminal like DUF3337 PF11816.8 CCH61401.1 - 2.7e-30 105.5 1.6 1e-29 103.6 1.6 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CCH61401.1 - 8.9e-05 23.2 9.9 0.093 13.6 0.1 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat RAWUL PF16207.5 CCH61401.1 - 0.098 13.3 0.1 0.098 13.3 0.1 2.8 3 0 0 3 3 3 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like PEPcase_2 PF14010.6 CCH61401.1 - 0.11 10.9 1.1 0.2 10.1 1.1 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Rad60-SLD_2 PF13881.6 CCH61401.1 - 0.12 12.4 0.1 0.47 10.6 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Thioredoxin PF00085.20 CCH61402.1 - 6.6e-16 58.2 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CCH61402.1 - 0.0011 19.2 0.5 0.0033 17.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 CCH61402.1 - 0.0073 15.7 0.1 0.012 14.9 0.1 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CCH61402.1 - 0.0081 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Fungal_trans PF04082.18 CCH61403.1 - 1.1e-10 41.0 1.6 1.1e-10 41.0 1.6 3.2 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH61403.1 - 3.3e-08 33.5 12.4 6.1e-08 32.6 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP1_TM PF14812.6 CCH61404.1 - 0.096 13.1 3.2 0.46 10.9 3.2 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PQ-loop PF04193.14 CCH61405.1 - 1.3e-39 133.7 14.6 8.6e-22 76.7 1.0 3.0 3 0 0 3 3 3 2 PQ loop repeat Steroid_dh PF02544.16 CCH61405.1 - 0.053 13.5 0.7 0.053 13.5 0.7 2.5 2 1 1 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase MtN3_slv PF03083.16 CCH61405.1 - 0.46 10.6 6.0 0.19 11.8 0.8 2.7 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Rep_fac_C PF08542.11 CCH61406.1 - 3.7e-21 75.3 0.1 9e-21 74.1 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 CCH61406.1 - 1.6e-13 51.3 0.0 3.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CCH61406.1 - 4.8e-13 49.2 0.1 3.4e-10 39.9 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_14 PF13173.6 CCH61406.1 - 1.2e-07 31.9 0.0 2.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH61406.1 - 1.4e-06 28.8 0.0 0.00018 21.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 CCH61406.1 - 4.5e-06 26.6 0.0 1.3e-05 25.1 0.0 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CCH61406.1 - 7.1e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CCH61406.1 - 9.7e-06 25.6 0.0 3e-05 24.0 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 CCH61406.1 - 3.2e-05 24.2 0.1 0.064 13.5 0.1 2.5 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.12 CCH61406.1 - 8.6e-05 22.3 0.0 0.0005 19.8 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CCH61406.1 - 0.00018 21.0 0.1 0.003 17.0 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 CCH61406.1 - 0.0007 19.4 0.3 0.0012 18.7 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CCH61406.1 - 0.0036 17.6 0.1 0.011 16.1 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain MeaB PF03308.16 CCH61406.1 - 0.0044 16.1 0.0 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CCH61406.1 - 0.0065 16.4 0.1 0.041 13.8 0.0 2.2 1 1 1 2 2 2 1 NTPase TniB PF05621.11 CCH61406.1 - 0.0096 15.3 0.1 3.4 7.0 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein AAA_19 PF13245.6 CCH61406.1 - 0.012 16.0 0.2 0.061 13.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CCH61406.1 - 0.032 14.0 0.4 0.055 13.2 0.4 1.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CCH61406.1 - 0.034 13.5 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CCH61406.1 - 0.041 13.4 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 CCH61406.1 - 0.054 12.7 0.0 0.12 11.6 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 CCH61406.1 - 0.057 13.1 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CCH61406.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCH61406.1 - 0.062 13.8 0.1 0.15 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 CCH61406.1 - 0.08 12.9 0.2 0.87 9.6 0.0 2.6 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCH61406.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase SRP54 PF00448.22 CCH61406.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CCH61406.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 NACHT domain DEAD PF00270.29 CCH61406.1 - 0.12 12.2 0.1 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase YL1 PF05764.13 CCH61407.1 - 1.1e-49 169.8 38.2 1.1e-49 169.8 38.2 3.0 2 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 CCH61407.1 - 4.2e-12 45.6 0.8 6.8e-12 44.9 0.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain POPLD PF08170.12 CCH61407.1 - 8 6.9 6.0 2.8 8.3 1.1 2.6 2 0 0 2 2 2 0 POPLD (NUC188) domain Tctex-1 PF03645.13 CCH61407.1 - 8.9 6.6 8.5 5.5 7.3 1.4 3.1 2 0 0 2 2 2 0 Tctex-1 family Snf7 PF03357.21 CCH61408.1 - 1.3e-38 132.3 20.3 1.5e-38 132.1 20.3 1.1 1 0 0 1 1 1 1 Snf7 Fmp27_WPPW PF10359.9 CCH61408.1 - 0.0004 19.4 10.3 0.00049 19.1 9.8 1.3 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain FliJ PF02050.16 CCH61408.1 - 0.0016 18.7 8.9 0.0016 18.7 8.9 2.3 1 1 1 2 2 2 1 Flagellar FliJ protein DUF5082 PF16888.5 CCH61408.1 - 0.021 15.1 3.0 0.021 15.1 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) YlqD PF11068.8 CCH61408.1 - 0.081 13.3 20.5 1.4 9.3 20.5 2.3 1 1 0 1 1 1 0 YlqD protein Not3 PF04065.15 CCH61408.1 - 0.13 11.7 15.8 0.021 14.2 10.5 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component TrfA PF07042.11 CCH61408.1 - 0.2 10.7 1.7 0.26 10.3 1.7 1.1 1 0 0 1 1 1 0 TrfA protein SKA1 PF07160.12 CCH61408.1 - 0.2 11.5 14.3 0.14 12.0 11.9 1.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Tropomyosin_1 PF12718.7 CCH61408.1 - 0.41 10.8 14.2 0.11 12.7 10.4 1.9 1 1 1 2 2 2 0 Tropomyosin like IL2 PF00715.17 CCH61408.1 - 0.43 10.5 7.3 0.65 9.9 7.3 1.3 1 0 0 1 1 1 0 Interleukin 2 Vps4_C PF09336.10 CCH61408.1 - 0.48 10.5 3.0 5.2 7.2 0.8 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Exonuc_VII_L PF02601.15 CCH61408.1 - 0.54 9.8 10.9 0.75 9.3 10.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.6 CCH61408.1 - 0.76 9.9 9.6 15 5.8 3.0 3.4 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 CCH61408.1 - 0.9 10.0 9.5 0.34 11.4 4.2 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 OmpH PF03938.14 CCH61408.1 - 1.1 9.6 22.7 0.3 11.4 14.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 CCH61408.1 - 2.6 8.5 8.5 2.6 8.5 0.2 3.5 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 CCH61408.1 - 2.8 6.5 11.1 2.1 6.8 9.2 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A Ntox28 PF15605.6 CCH61408.1 - 3.2 8.1 11.5 0.55 10.5 0.3 3.1 3 1 1 4 4 3 0 Bacterial toxin 28 GrpE PF01025.19 CCH61408.1 - 3.6 7.2 12.7 0.84 9.3 8.4 1.9 1 1 1 2 2 2 0 GrpE DUF1664 PF07889.12 CCH61408.1 - 3.9 7.5 17.2 3.4 7.7 5.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IFT20 PF14931.6 CCH61408.1 - 4.5 7.5 13.2 0.18 12.0 2.9 2.9 1 1 2 3 3 3 0 Intraflagellar transport complex B, subunit 20 Prefoldin PF02996.17 CCH61408.1 - 4.7 7.1 13.9 0.14 12.1 1.5 3.3 1 1 3 4 4 4 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 CCH61408.1 - 4.9 7.4 14.3 2 8.6 3.3 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 CCH61408.1 - 5.5 6.0 15.3 6.1 5.8 14.3 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 CCH61408.1 - 5.5 7.2 18.9 6.4 7.0 4.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 CCH61408.1 - 8.9 5.6 15.5 18 4.6 15.5 1.4 1 1 0 1 1 1 0 FAM76 protein IZUMO PF15005.6 CCH61408.1 - 9.4 6.8 9.3 27 5.2 8.4 2.0 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Cob_adeno_trans PF01923.18 CCH61408.1 - 9.4 6.3 7.5 2.6 8.2 2.1 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase rve PF00665.26 CCH61409.1 - 1.6e-08 34.7 0.1 3.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Tubulin-binding PF00418.19 CCH61409.1 - 0.082 12.9 0.0 0.32 11.0 0.0 2.1 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat AcetylCoA_hydro PF02550.15 CCH61410.1 - 3.1e-66 223.1 0.0 6.3e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CCH61410.1 - 5.7e-41 140.0 0.0 9.1e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 CCH61410.1 - 0.06 12.7 0.0 0.45 9.9 0.0 2.3 2 1 0 2 2 2 0 Coenzyme A transferase CitF PF04223.12 CCH61410.1 - 0.17 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) DNA_topoisoIV PF00521.20 CCH61411.1 - 2.2e-125 418.9 1.1 2.2e-125 418.9 1.1 2.5 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CCH61411.1 - 8.2e-50 168.4 1.4 8.2e-50 168.4 1.4 2.6 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CCH61411.1 - 1.7e-24 86.3 2.5 3.6e-24 85.2 2.5 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CCH61411.1 - 1.9e-13 50.9 0.4 2.2e-12 47.4 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CCH61411.1 - 3.4e-07 30.4 0.0 1.2e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Toprim domain C2 PF00168.30 CCH61412.1 - 3.7e-56 187.8 3.9 8.8e-22 77.3 0.3 4.9 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 CCH61412.1 - 0.00086 18.8 0.2 0.0015 18.1 0.2 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain OST3_OST6 PF04756.13 CCH61413.1 - 1.3e-81 274.2 0.9 1.5e-81 273.9 0.9 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CCH61413.1 - 0.0034 17.3 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Wzy_C PF04932.15 CCH61413.1 - 1.2 8.8 8.9 1.7 8.2 0.6 3.0 3 0 0 3 3 3 0 O-Antigen ligase MKT1_C PF12246.8 CCH61414.1 - 4.6e-58 196.3 4.0 4.8e-57 193.0 4.5 2.2 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CCH61414.1 - 5.3e-27 94.0 0.1 2.5e-26 91.8 0.1 2.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CCH61414.1 - 8.4e-22 77.6 0.0 3.4e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 CCH61414.1 - 0.0081 16.5 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 XPG I-region CC190 PF15768.5 CCH61414.1 - 0.55 10.2 9.1 1.1 9.3 9.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 4HBT PF03061.22 CCH61415.1 - 9.4e-05 22.7 0.2 0.086 13.2 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily EF-hand_4 PF12763.7 CCH61416.1 - 7e-49 164.1 5.3 1.3e-45 153.6 1.2 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 CCH61416.1 - 5.7e-40 137.6 9.6 5.7e-40 137.6 9.6 1.7 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 DUF3829 PF12889.7 CCH61416.1 - 0.00051 19.6 8.2 0.0025 17.3 6.6 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3829) Phage_GP20 PF06810.11 CCH61416.1 - 0.018 14.8 6.3 0.15 11.8 2.2 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 L27 PF02828.16 CCH61416.1 - 0.03 14.1 0.0 0.072 12.9 0.0 1.6 1 0 0 1 1 1 0 L27 domain Phage_lysis PF03245.13 CCH61416.1 - 0.041 14.0 0.8 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Mito_fiss_reg PF05308.11 CCH61416.1 - 0.07 13.2 5.7 0.12 12.4 5.7 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator ABC_tran_CTD PF16326.5 CCH61416.1 - 0.089 13.1 7.6 1.8 8.9 5.2 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF5320 PF17253.2 CCH61416.1 - 0.12 13.5 5.3 1.4 10.0 0.3 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF4140 PF13600.6 CCH61416.1 - 0.12 12.8 3.8 1.4 9.4 1.5 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CorA PF01544.18 CCH61416.1 - 0.5 9.6 6.4 1.1 8.5 6.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FlxA PF14282.6 CCH61416.1 - 0.5 10.4 22.4 0.03 14.3 7.2 3.1 2 1 0 3 3 2 0 FlxA-like protein CENP-F_leu_zip PF10473.9 CCH61416.1 - 0.5 10.4 14.4 17 5.4 14.4 2.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 CCH61416.1 - 0.89 10.2 8.4 3.3 8.4 2.9 2.7 2 0 0 2 2 2 0 SlyX DUF641 PF04859.12 CCH61416.1 - 0.93 9.8 6.7 4.1 7.7 0.2 2.6 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) CCDC-167 PF15188.6 CCH61416.1 - 1.3 9.4 13.9 15 6.0 9.0 3.4 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 SprA-related PF12118.8 CCH61416.1 - 1.7 7.7 12.8 0.42 9.7 9.5 1.5 2 0 0 2 2 2 0 SprA-related family EF-hand_1 PF00036.32 CCH61416.1 - 1.7 8.3 10.4 0.076 12.6 2.9 2.6 3 0 0 3 3 2 0 EF hand Tropomyosin_1 PF12718.7 CCH61416.1 - 1.9 8.7 14.6 16 5.6 9.2 2.5 1 1 0 2 2 2 0 Tropomyosin like FlaC_arch PF05377.11 CCH61416.1 - 2.2 8.7 8.2 19 5.7 2.1 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2408 PF10303.9 CCH61416.1 - 4.9 7.7 12.6 9 6.9 8.7 2.6 2 1 0 2 2 1 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.8 CCH61416.1 - 5.2 7.1 15.7 11 6.1 0.6 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 CCH61416.1 - 6 7.2 11.7 2.8e+02 1.9 11.7 2.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc24 PF08286.11 CCH61416.1 - 9.2 6.6 15.0 2.8 8.2 5.8 2.9 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.11 CCH61416.1 - 9.6 6.8 12.9 42 4.8 8.0 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Ribosomal_S13 PF00416.22 CCH61417.1 - 3.4e-18 66.3 0.0 3.8e-16 59.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 IMS_HHH PF11798.8 CCH61417.1 - 0.0018 18.5 0.2 0.017 15.4 0.0 2.6 3 0 0 3 3 3 1 IMS family HHH motif FbpA PF05833.11 CCH61417.1 - 0.0075 15.1 0.0 0.0075 15.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Tropomyosin_1 PF12718.7 CCH61418.1 - 3.6e-48 163.4 47.3 4.2e-48 163.1 47.3 1.0 1 0 0 1 1 1 1 Tropomyosin like CENP-F_leu_zip PF10473.9 CCH61418.1 - 1.4e-05 25.1 46.3 0.00063 19.8 15.0 2.9 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Lebercilin PF15619.6 CCH61418.1 - 6.8e-05 22.6 38.5 8.4e-05 22.3 38.5 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 CCH61418.1 - 8.3e-05 22.0 43.0 0.0031 16.9 36.1 3.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 CCH61418.1 - 0.00019 20.9 42.7 0.014 14.8 22.9 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 CCH61418.1 - 0.00048 20.3 31.6 0.055 13.7 13.5 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein Filament PF00038.21 CCH61418.1 - 0.0023 17.6 34.4 0.0089 15.7 18.1 2.0 1 1 1 2 2 2 1 Intermediate filament protein MbeD_MobD PF04899.12 CCH61418.1 - 0.0025 17.9 1.2 0.0025 17.9 1.2 3.0 2 1 1 3 3 3 1 MbeD/MobD like ATG16 PF08614.11 CCH61418.1 - 0.0031 17.8 40.8 0.078 13.2 12.7 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CCH61418.1 - 0.0037 16.6 35.6 0.11 11.8 11.7 2.5 1 1 2 3 3 3 2 Protein of unknown function (DUF3450) Spc7 PF08317.11 CCH61418.1 - 0.0061 15.5 41.5 0.053 12.4 14.4 2.1 1 1 1 2 2 2 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CCH61418.1 - 0.0069 16.5 48.3 1.5 8.9 18.6 3.2 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein KELK PF15796.5 CCH61418.1 - 0.0096 16.4 9.3 0.0096 16.4 9.3 3.4 1 1 1 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Laminin_II PF06009.12 CCH61418.1 - 0.011 15.8 26.8 0.3 11.1 10.4 2.2 1 1 1 2 2 2 0 Laminin Domain II ZapB PF06005.12 CCH61418.1 - 0.013 15.9 50.7 1.6 9.2 11.7 3.7 2 1 1 3 3 3 0 Cell division protein ZapB DUF4201 PF13870.6 CCH61418.1 - 0.018 14.8 33.2 0.19 11.4 24.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) bZIP_1 PF00170.21 CCH61418.1 - 0.018 15.1 42.8 0.095 12.8 7.0 4.4 1 1 3 4 4 4 0 bZIP transcription factor TMF_DNA_bd PF12329.8 CCH61418.1 - 0.022 14.8 53.4 0.23 11.5 17.3 3.2 1 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding WXG100 PF06013.12 CCH61418.1 - 0.023 14.9 16.9 0.77 10.0 0.8 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Lectin_N PF03954.14 CCH61418.1 - 0.023 14.4 19.8 0.045 13.5 9.1 2.6 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Uso1_p115_C PF04871.13 CCH61418.1 - 0.024 15.0 48.1 0.81 10.1 25.8 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 CCH61418.1 - 0.031 14.4 38.4 0.27 11.3 11.3 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 CCH61418.1 - 0.037 14.3 32.2 0.22 11.8 7.4 3.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 CCH61418.1 - 0.05 14.0 35.9 0.03 14.8 31.4 1.9 1 1 1 2 2 2 0 Fez1 ERM PF00769.19 CCH61418.1 - 0.07 12.9 45.8 0.034 13.9 26.8 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 CCH61418.1 - 0.073 13.1 19.8 0.14 12.2 11.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Rho_Binding PF08912.11 CCH61418.1 - 0.086 13.7 7.9 0.086 13.7 7.9 3.9 1 1 2 3 3 2 0 Rho Binding DUF4472 PF14739.6 CCH61418.1 - 0.089 13.5 32.9 0.2 12.4 5.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) FlaC_arch PF05377.11 CCH61418.1 - 0.15 12.4 34.0 0.82 10.1 5.1 5.0 1 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.6 CCH61418.1 - 0.18 12.2 44.9 2 8.8 26.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Sec2p PF06428.11 CCH61418.1 - 0.22 11.5 39.9 0.043 13.8 21.7 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.9 CCH61418.1 - 0.32 11.2 42.3 0.75 10.0 27.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 EzrA PF06160.12 CCH61418.1 - 0.32 9.1 37.8 0.88 7.7 29.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF724 PF05266.14 CCH61418.1 - 0.34 10.7 34.2 0.4 10.5 17.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG17 PF04108.12 CCH61418.1 - 0.39 9.8 25.8 0.21 10.6 4.3 2.9 1 1 2 3 3 3 0 Autophagy protein Apg17 Ax_dynein_light PF10211.9 CCH61418.1 - 0.4 10.6 42.7 0.39 10.6 9.7 3.4 1 1 3 4 4 4 0 Axonemal dynein light chain DivIC PF04977.15 CCH61418.1 - 0.4 10.5 43.2 0.17 11.6 10.0 4.3 1 1 3 4 4 4 0 Septum formation initiator AAA_13 PF13166.6 CCH61418.1 - 0.46 9.1 34.9 0.038 12.6 9.9 2.0 1 1 1 2 2 2 0 AAA domain DUF3584 PF12128.8 CCH61418.1 - 0.55 7.7 34.8 0.61 7.5 34.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FapA PF03961.13 CCH61418.1 - 0.57 8.7 35.5 0.11 11.1 12.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FemAB PF02388.16 CCH61418.1 - 0.61 8.9 30.5 0.17 10.8 13.8 2.0 1 1 1 2 2 2 0 FemAB family APG6_N PF17675.1 CCH61418.1 - 0.63 10.6 52.6 8.9 6.9 30.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 CCH61418.1 - 0.65 10.2 36.6 0.43 10.8 5.2 4.3 1 1 3 4 4 4 0 Haemolysin XhlA DUF4407 PF14362.6 CCH61418.1 - 0.76 9.1 28.3 1.6 8.1 28.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) IFT57 PF10498.9 CCH61418.1 - 0.81 8.6 33.2 0.23 10.4 13.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HIP1_clath_bdg PF16515.5 CCH61418.1 - 0.84 10.3 38.9 0.12 12.9 20.4 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PI3K_P85_iSH2 PF16454.5 CCH61418.1 - 1 9.0 34.0 0.65 9.6 27.8 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HOOK PF05622.12 CCH61418.1 - 1.1 7.4 38.3 1.3 7.0 38.3 1.2 1 0 0 1 1 1 0 HOOK protein HALZ PF02183.18 CCH61418.1 - 1.1 9.5 35.6 0.94 9.8 9.5 5.1 3 2 1 4 4 3 0 Homeobox associated leucine zipper CASP_C PF08172.12 CCH61418.1 - 1.2 8.5 29.1 1.5 8.1 21.3 2.2 1 1 1 2 2 2 0 CASP C terminal FUSC PF04632.12 CCH61418.1 - 1.2 7.5 5.4 1.3 7.4 5.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Sec34 PF04136.15 CCH61418.1 - 1.3 8.9 26.3 4.4 7.2 9.8 2.1 1 1 1 2 2 2 0 Sec34-like family Mod_r PF07200.13 CCH61418.1 - 1.3 9.1 41.1 0.43 10.7 17.7 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CENP-H PF05837.12 CCH61418.1 - 1.7 9.1 35.8 1.2 9.6 10.6 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4795 PF16043.5 CCH61418.1 - 1.7 8.2 34.8 9.6 5.7 34.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 CCH61418.1 - 1.8 9.1 28.3 5 7.7 12.5 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 CCH61418.1 - 1.8 7.7 30.3 3 7.0 15.9 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF5082 PF16888.5 CCH61418.1 - 1.9 8.8 28.2 8.5 6.7 15.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) OmpH PF03938.14 CCH61418.1 - 2 8.7 42.5 2.5 8.4 23.7 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 CCH61418.1 - 2.1 8.4 44.5 9.8 6.2 25.8 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 CCH61418.1 - 2.1 8.6 40.9 2.5 8.3 18.1 3.7 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 Leu_zip PF15294.6 CCH61418.1 - 2.1 7.8 35.3 7.4 6.0 35.3 1.7 1 1 0 1 1 1 0 Leucine zipper bZIP_2 PF07716.15 CCH61418.1 - 2.3 8.4 42.4 0.24 11.5 3.8 5.0 2 2 3 5 5 5 0 Basic region leucine zipper NPV_P10 PF05531.12 CCH61418.1 - 2.7 8.5 18.0 1 9.9 0.7 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 CCH61418.1 - 2.8 6.7 40.4 8.6 5.1 23.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FliD_C PF07195.12 CCH61418.1 - 2.8 7.3 25.7 0.9 8.9 1.6 3.4 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus CLZ PF16526.5 CCH61418.1 - 3.8 7.9 32.9 4.4 7.7 3.4 3.9 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3573 PF12097.8 CCH61418.1 - 4 6.2 7.0 4.3 6.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) CENP-K PF11802.8 CCH61418.1 - 4.4 6.8 34.0 1 8.8 15.2 1.8 1 1 1 2 2 2 0 Centromere-associated protein K HAUS6_N PF14661.6 CCH61418.1 - 4.5 6.8 27.7 1.3 8.5 13.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Acetyltransf_11 PF13720.6 CCH61418.1 - 4.7 7.8 9.2 0.72 10.4 0.7 2.9 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF948 PF06103.11 CCH61418.1 - 4.7 7.5 15.9 1.4 9.3 2.7 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 CCH61418.1 - 4.7 6.2 33.3 0.77 8.8 16.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SYCE1 PF15233.6 CCH61418.1 - 5.2 7.1 40.5 2.8 8.0 31.6 2.0 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Prefoldin_3 PF13758.6 CCH61418.1 - 5.3 7.2 25.1 0.23 11.5 6.3 3.5 1 1 1 2 2 1 0 Prefoldin subunit Spc24 PF08286.11 CCH61418.1 - 5.6 7.3 41.8 6.7 7.0 7.8 4.0 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 Occludin_ELL PF07303.13 CCH61418.1 - 6.5 7.5 25.3 8.9 7.1 8.9 3.0 1 1 1 2 2 2 0 Occludin homology domain KASH_CCD PF14662.6 CCH61418.1 - 6.9 6.5 43.8 0.78 9.5 32.7 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 CCH61418.1 - 7.2 6.6 48.7 1.7 8.6 9.1 4.1 1 1 3 4 4 4 0 Prefoldin subunit SlyX PF04102.12 CCH61418.1 - 8.3 7.1 21.9 3 8.5 3.1 3.7 1 1 3 4 4 4 0 SlyX Fib_alpha PF08702.10 CCH61418.1 - 8.5 6.6 26.4 18 5.5 7.6 2.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3552 PF12072.8 CCH61418.1 - 9 5.6 40.1 1.8 7.9 20.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) TMF_TATA_bd PF12325.8 CCH61418.1 - 9.5 6.5 37.9 3.9 7.7 11.2 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.11 CCH61418.1 - 10 5.9 41.8 46 3.8 23.0 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 Peptidase_M1 PF01433.20 CCH61419.1 - 1.5e-52 178.3 3.6 3.2e-52 177.2 3.6 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCH61419.1 - 1.7e-33 116.4 7.9 4.2e-33 115.1 7.9 1.8 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CCH61419.1 - 6e-28 98.3 0.2 8.8e-28 97.8 0.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain BSP PF04450.12 CCH61419.1 - 0.0084 15.9 0.3 0.035 13.9 0.1 2.0 2 0 0 2 2 2 1 Peptidase of plants and bacteria DnaJ_C PF01556.18 CCH61420.1 - 3.9e-30 104.9 0.3 5.5e-30 104.4 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCH61420.1 - 2.5e-23 82.0 3.3 6.2e-23 80.7 3.3 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCH61420.1 - 1.4e-10 41.4 14.7 2.8e-10 40.4 14.7 1.5 1 0 0 1 1 1 1 DnaJ central domain zf-RING_10 PF16685.5 CCH61420.1 - 0.82 9.9 3.4 7.9 6.7 2.4 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 VWA_N2 PF16164.5 CCH61420.1 - 2.1 8.5 7.2 1.5 9.0 4.0 2.2 1 1 1 2 2 2 0 VWA N-terminal DUF5351 PF17302.2 CCH61420.1 - 7.2 6.9 17.2 1.3 9.3 5.1 3.9 3 1 1 4 4 4 0 Family of unknown function (DUF5351) tRNA-synt_2 PF00152.20 CCH61422.1 - 1.3e-60 205.2 0.0 1.8e-60 204.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCH61422.1 - 3.3e-07 30.2 0.0 6.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCH61422.1 - 8.3e-07 28.7 0.1 0.0014 18.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 CCH61422.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF3605 PF12239.8 CCH61423.1 - 6e-38 130.6 7.2 7.1e-38 130.3 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) RNase_HII PF01351.18 CCH61424.1 - 4.7e-66 222.4 0.0 6e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII LPD29 PF18847.1 CCH61424.1 - 0.042 14.8 0.5 0.19 12.7 0.2 2.2 1 1 1 2 2 2 0 Large polyvalent protein associated domain 29 Tom7 PF08038.12 CCH61425.1 - 8.7e-19 66.9 0.1 1.1e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 TOM7 family CSM2 PF16834.5 CCH61426.1 - 2.8e-68 229.5 12.1 6.9e-68 228.2 12.1 1.5 1 1 0 1 1 1 1 Shu complex component Csm2, DNA-binding Forkhead PF00250.18 CCH61427.1 - 1.2e-32 112.0 0.2 1.2e-32 112.0 0.2 2.2 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CCH61427.1 - 2.6e-11 43.7 0.1 2.3e-10 40.6 0.1 2.6 1 1 1 2 2 2 1 FHA domain Linker_histone PF00538.19 CCH61427.1 - 0.00091 19.5 0.1 0.0036 17.6 0.1 2.1 1 0 0 1 1 1 1 linker histone H1 and H5 family MOR2-PAG1_N PF14222.6 CCH61428.1 - 4.8e-172 573.8 5.4 8.9e-172 572.9 5.4 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CCH61428.1 - 5.7e-87 291.8 1.2 1.8e-86 290.1 1.2 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CCH61428.1 - 3.8e-24 84.5 15.5 1.4e-09 36.3 0.7 3.8 3 2 0 3 3 3 3 Cell morphogenesis central region Symplekin_C PF12295.8 CCH61428.1 - 0.016 15.3 0.6 8.1 6.5 0.0 3.2 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal Cnd1 PF12717.7 CCH61428.1 - 0.049 13.7 6.7 0.12 12.5 0.1 4.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RRT14 PF17075.5 CCH61429.1 - 6.9e-51 173.2 23.4 8.1e-51 173.0 23.4 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 Ribonuclease_3 PF00636.26 CCH61429.1 - 0.089 13.4 1.0 0.19 12.4 0.3 1.9 1 1 1 2 2 2 0 Ribonuclease III domain DNApol_Exo PF18136.1 CCH61429.1 - 0.8 8.8 9.3 1 8.4 9.3 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain Ribosomal_L6 PF00347.23 CCH61430.1 - 1.2e-27 96.4 12.6 6.4e-15 55.6 4.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.16 CCH61430.1 - 0.12 12.0 0.5 0.25 11.0 0.1 1.7 2 0 0 2 2 2 0 Transcriptional Coactivator p15 (PC4) Transket_pyr PF02779.24 CCH61431.1 - 2.2e-64 216.4 0.0 3.7e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CCH61431.1 - 7e-58 195.9 0.0 9.9e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CCH61431.1 - 4.6e-49 166.0 0.0 7.3e-49 165.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CCH61431.1 - 6e-19 67.4 2.7 6e-19 67.4 2.7 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus SUN PF03856.13 CCH61432.1 - 5.6e-100 333.8 10.7 9e-100 333.2 10.7 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Dehydrin PF00257.19 CCH61432.1 - 0.32 11.5 11.1 0.6 10.6 11.1 1.4 1 0 0 1 1 1 0 Dehydrin MFS_1 PF07690.16 CCH61433.1 - 2.2e-41 142.0 28.7 7.5e-40 136.9 12.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH61433.1 - 3.1e-12 46.1 2.9 3.1e-12 46.1 2.9 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CCH61433.1 - 1.2e-06 27.2 4.3 2.3e-06 26.3 4.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 CCH61433.1 - 0.001 18.1 0.8 0.0018 17.3 0.8 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF2953 PF11167.8 CCH61433.1 - 0.036 14.2 0.1 0.098 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) CxC2 PF18803.1 CCH61433.1 - 0.072 13.3 0.3 7.5 6.8 0.0 2.7 2 0 0 2 2 2 0 CxC2 like cysteine cluster associated with KDZ transposases Gly-zipper_Omp PF13488.6 CCH61433.1 - 0.65 10.0 3.2 1.3 9.1 3.2 1.5 1 0 0 1 1 1 0 Glycine zipper MFS_1 PF07690.16 CCH61434.1 - 1.1e-36 126.5 29.7 3.3e-36 125.0 9.6 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH61434.1 - 4.6e-08 32.3 9.7 4.6e-08 32.3 9.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CCH61434.1 - 3.5e-07 29.0 5.3 5.9e-07 28.3 5.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 CCH61434.1 - 0.0065 15.4 1.2 0.0065 15.4 1.2 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Claudin_2 PF13903.6 CCH61434.1 - 0.066 13.0 0.0 0.066 13.0 0.0 3.2 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction DnaJ_C PF01556.18 CCH61435.1 - 5.3e-40 136.9 0.3 7e-40 136.5 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCH61435.1 - 2.6e-26 91.5 0.6 4.3e-26 90.8 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCH61435.1 - 3.8e-15 56.0 17.8 7.7e-15 55.0 17.8 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CCH61435.1 - 0.14 12.2 9.5 0.51 10.4 1.2 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 CCH61435.1 - 0.17 11.9 9.0 1.4 9.0 8.9 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 CCH61435.1 - 0.61 10.1 15.3 0.2 11.7 2.7 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 CCH61435.1 - 2.4 8.7 11.5 0.62 10.6 1.8 3.1 2 1 1 3 3 3 0 Cytochrome c3 Myb_DNA-bind_4 PF13837.6 CCH61436.1 - 0.00073 19.9 0.2 0.00073 19.9 0.2 3.0 3 1 1 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH61436.1 - 0.03 14.6 4.3 0.034 14.4 0.4 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Methyltransf_31 PF13847.6 CCH61437.1 - 2.6e-07 30.6 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCH61437.1 - 3.4e-07 30.0 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CCH61437.1 - 3.9e-06 27.5 0.0 6.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 CCH61437.1 - 2.1e-05 24.0 0.1 5.1e-05 22.7 0.0 1.6 1 1 1 2 2 2 1 N-6 DNA Methylase Methyltransf_23 PF13489.6 CCH61437.1 - 8.5e-05 22.4 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CCH61437.1 - 0.00013 21.7 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 CCH61437.1 - 0.0023 17.4 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.8 CCH61437.1 - 0.0033 16.9 0.0 0.0055 16.2 0.0 1.4 1 1 0 1 1 1 1 RRNA methyltransferase AviRa TRM PF02005.16 CCH61437.1 - 0.0059 15.8 0.0 0.0067 15.6 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_10 PF05971.12 CCH61437.1 - 0.0071 15.7 0.1 0.013 14.8 0.1 1.4 1 1 0 1 1 1 1 RNA methyltransferase FtsJ PF01728.19 CCH61437.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 CCH61437.1 - 0.019 15.6 0.0 0.036 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CCH61437.1 - 0.031 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 CCH61437.1 - 0.053 13.3 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 CCH61437.1 - 0.069 13.9 0.0 0.11 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Gcd10p PF04189.13 CCH61438.1 - 7.5e-92 307.6 8.6 1e-91 307.2 8.6 1.2 1 0 0 1 1 1 1 Gcd10p family CNP_C_terminal PF17839.1 CCH61438.1 - 0.025 15.3 4.7 0.059 14.1 0.2 2.8 2 0 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Cnd1 PF12717.7 CCH61438.1 - 0.34 10.9 2.6 0.7 9.9 2.6 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Methyltr_RsmB-F PF01189.17 CCH61439.1 - 7.8e-81 270.5 1.4 8.8e-81 270.3 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CCH61439.1 - 5.4e-08 33.2 0.4 2.9e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CCH61439.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase SelP_N PF04592.14 CCH61439.1 - 3.4 7.0 16.9 7.1 6.0 16.9 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Actin PF00022.19 CCH61440.1 - 5e-51 173.6 0.0 5.6e-30 104.3 0.0 2.5 2 2 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CCH61440.1 - 0.081 11.7 0.0 0.69 8.7 0.0 2.5 4 0 0 4 4 4 0 MreB/Mbl protein Ras PF00071.22 CCH61441.1 - 2e-57 193.3 0.1 2.3e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH61441.1 - 3.8e-22 78.8 0.0 6.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH61441.1 - 2.1e-09 37.1 0.0 3.2e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCH61441.1 - 0.0026 17.0 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CCH61441.1 - 0.003 17.6 0.0 0.0068 16.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CCH61441.1 - 0.004 16.6 0.0 0.0056 16.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCH61441.1 - 0.0092 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCH61441.1 - 0.023 14.6 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CCH61441.1 - 0.051 14.1 0.2 0.1 13.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CCH61441.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF3113 PF11310.8 CCH61442.1 - 0.071 13.1 1.2 0.17 11.8 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) Antimicrobial24 PF16049.5 CCH61442.1 - 0.48 10.4 2.7 0.82 9.7 2.7 1.3 1 0 0 1 1 1 0 Frog antimicrobial peptide Y_phosphatase2 PF03162.13 CCH61443.1 - 1.4e-51 174.3 0.0 1.7e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCH61443.1 - 5.1e-06 26.6 0.0 6.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family NUP214 PF16755.5 CCH61444.1 - 2.6e-105 352.6 11.1 2.6e-105 352.6 11.1 2.2 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Sua5_yciO_yrdC PF01300.18 CCH61445.1 - 2e-48 164.3 0.0 3.2e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CCH61445.1 - 1.1e-31 110.2 0.0 1.7e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding KAR9 PF08580.10 CCH61445.1 - 0.047 12.2 3.6 0.029 13.0 0.8 1.8 2 0 0 2 2 2 0 Yeast cortical protein KAR9 DUF928 PF06051.12 CCH61445.1 - 0.15 11.9 1.0 0.33 10.8 0.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF928) RNA_pol_Rpb2_6 PF00562.28 CCH61446.1 - 1.4e-115 386.5 0.0 2.7e-115 385.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCH61446.1 - 3.9e-46 157.1 0.0 5.5e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCH61446.1 - 6.8e-34 117.2 0.0 1.3e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CCH61446.1 - 2.8e-27 94.7 0.1 1.6e-26 92.3 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CCH61446.1 - 1.1e-23 83.0 0.0 2.4e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CCH61446.1 - 8.3e-17 61.4 0.0 6.6e-15 55.3 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 B12D PF06522.11 CCH61447.1 - 0.00076 19.2 0.0 0.00091 19.0 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-C2H2 PF00096.26 CCH61448.1 - 2e-09 37.4 10.4 0.00018 21.8 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH61448.1 - 3.2e-06 27.5 9.3 0.019 15.8 1.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCH61448.1 - 0.00037 20.8 12.1 0.0005 20.4 0.8 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CCH61448.1 - 0.011 16.1 0.5 0.011 16.1 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCH61448.1 - 0.028 15.0 1.7 0.055 14.1 0.1 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF5320 PF17253.2 CCH61449.1 - 0.06 14.4 0.2 0.21 12.7 0.2 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5320) CAF1A PF12253.8 CCH61450.1 - 3.3e-22 78.4 9.3 3.3e-22 78.4 9.3 3.4 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A MCM PF00493.23 CCH61451.1 - 2.2e-100 334.4 0.0 3.5e-100 333.7 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCH61451.1 - 1.3e-37 128.4 0.6 2.4e-37 127.6 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCH61451.1 - 1.7e-30 105.3 1.6 4.2e-30 104.0 1.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCH61451.1 - 3e-18 66.3 3.6 1.1e-17 64.5 3.6 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCH61451.1 - 1.6e-05 24.4 0.0 0.00064 19.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCH61451.1 - 2.3e-05 24.4 0.0 6.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCH61451.1 - 0.00074 19.4 0.0 0.011 15.6 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCH61451.1 - 0.1 12.3 0.1 3.5 7.3 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain N_Asn_amidohyd PF14736.6 CCH61451.1 - 0.12 11.5 0.3 0.26 10.4 0.3 1.5 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase AAA_16 PF13191.6 CCH61451.1 - 0.14 12.5 2.4 1.1 9.6 0.1 3.2 3 1 0 3 3 3 0 AAA ATPase domain HTH_40 PF14493.6 CCH61451.1 - 1.1 9.7 5.6 23 5.5 0.3 3.1 2 1 1 3 3 3 0 Helix-turn-helix domain Bud13 PF09736.9 CCH61452.1 - 4.6e-27 95.2 3.3 4.6e-27 95.2 3.3 3.5 2 2 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF4637 PF15470.6 CCH61452.1 - 0.36 10.5 0.1 0.36 10.5 0.1 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF4637) Mannosyl_trans3 PF11051.8 CCH61454.1 - 1.8e-68 230.9 1.6 3.5e-68 229.9 1.6 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Rpp20 PF12328.8 CCH61455.1 - 2.4e-17 63.2 1.4 1.1e-15 57.8 1.4 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CCH61455.1 - 2.4e-07 30.5 0.1 4.3e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Alba Transketolase_C PF02780.20 CCH61455.1 - 0.0099 15.8 0.0 0.02 14.7 0.0 1.6 1 1 0 1 1 1 1 Transketolase, C-terminal domain PDH PF02153.17 CCH61456.1 - 1.1e-10 40.9 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 CCH61456.1 - 0.00047 19.6 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CCH61456.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CCH61456.1 - 0.0048 17.1 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CCH61456.1 - 0.007 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCH61456.1 - 0.016 15.7 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 CCH61456.1 - 0.15 12.3 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 CCH61456.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Arf PF00025.21 CCH61457.1 - 5.4e-76 253.9 0.2 6.1e-76 253.7 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCH61457.1 - 2.5e-16 60.0 0.1 3.4e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCH61457.1 - 2.3e-11 43.6 0.0 2.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCH61457.1 - 4.3e-11 42.6 0.0 5.1e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCH61457.1 - 5.8e-11 42.1 0.5 1.3e-06 27.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCH61457.1 - 1.2e-09 37.9 0.0 1.5e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH61457.1 - 7.1e-05 22.9 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH61457.1 - 0.00015 21.3 0.2 0.0014 18.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CCH61457.1 - 0.00097 19.7 0.9 0.004 17.7 0.9 1.8 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CCH61457.1 - 0.0025 16.9 0.7 0.11 11.5 0.2 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CCH61457.1 - 0.053 14.1 0.1 0.13 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 CCH61457.1 - 0.13 11.8 0.7 9.3 5.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 CCH61457.1 - 0.13 11.8 0.4 0.7 9.5 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 2-Hacid_dh_C PF02826.19 CCH61459.1 - 1.2e-35 122.5 0.0 1.8e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCH61459.1 - 2.9e-05 23.7 0.0 3.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 CCH61459.1 - 0.055 13.5 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CCH61459.1 - 0.11 12.9 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding UPF0728 PF15092.6 CCH61459.1 - 0.12 12.3 0.1 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 TFIIA PF03153.13 CCH61460.1 - 5.9e-43 148.4 26.1 2.1e-23 84.0 18.1 2.2 1 1 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit D123 PF07065.14 CCH61460.1 - 0.0096 15.1 2.8 0.017 14.3 2.8 1.4 1 0 0 1 1 1 1 D123 AceK PF06315.11 CCH61460.1 - 0.11 11.0 0.2 0.17 10.4 0.2 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Presenilin PF01080.17 CCH61460.1 - 2.9 6.6 7.0 3.8 6.2 7.0 1.1 1 0 0 1 1 1 0 Presenilin Fungal_TACC PF12709.7 CCH61461.1 - 3e-10 40.4 1.3 3e-10 40.4 1.3 10.1 2 2 7 10 10 10 2 Fungal Transforming acidic coiled-coil (TACC) proteins RhoGAP PF00620.27 CCH61462.1 - 1.7e-32 112.4 0.5 1.7e-32 112.4 0.5 2.4 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 CCH61462.1 - 1.1e-10 41.9 0.0 5.8e-10 39.6 0.0 2.3 1 0 0 1 1 1 1 PH domain PX PF00787.24 CCH61462.1 - 2.1e-05 24.5 0.1 0.00018 21.4 0.0 2.7 3 0 0 3 3 3 1 PX domain Hist_deacetyl PF00850.19 CCH61463.1 - 3.8e-53 181.0 0.1 8.9e-53 179.8 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain FapA PF03961.13 CCH61464.1 - 0.00011 21.0 16.6 0.00011 21.0 16.6 4.0 1 1 3 4 4 4 1 Flagellar Assembly Protein A AP_endonuc_2 PF01261.24 CCH61464.1 - 0.034 13.6 0.2 0.072 12.5 0.2 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Pox_A_type_inc PF04508.12 CCH61464.1 - 0.062 13.2 2.4 0.16 11.9 0.1 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Pox_F11 PF04943.12 CCH61464.1 - 0.11 11.5 11.7 0.33 10.0 10.8 2.0 2 0 0 2 2 2 0 Poxvirus F11 protein Baculo_PEP_C PF04513.12 CCH61464.1 - 0.37 10.8 30.9 1.2 9.1 3.7 5.2 2 1 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CCH61464.1 - 8.6 6.9 29.3 0.16 12.4 2.2 5.2 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.29 CCH61465.1 - 5.2e-48 163.1 0.0 1e-47 162.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61465.1 - 1e-31 109.5 0.3 7.8e-31 106.7 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH61465.1 - 0.00011 22.3 0.0 0.00011 22.3 0.0 4.2 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CCH61465.1 - 0.029 13.7 0.0 0.1 11.9 0.0 1.9 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit APG6 PF04111.12 CCH61466.1 - 1.5e-55 187.9 8.4 1.2e-41 142.6 2.8 2.8 1 1 0 2 2 2 2 Apg6 BARA domain APG6_N PF17675.1 CCH61466.1 - 1.3e-26 93.6 16.0 1.3e-26 93.6 16.0 2.8 3 0 0 3 3 3 1 Apg6 coiled-coil region PH_9 PF15410.6 CCH61466.1 - 0.0052 17.1 0.1 0.017 15.5 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Noc2 PF03715.13 CCH61467.1 - 6.1e-82 275.2 10.9 6.1e-82 275.2 10.9 2.0 2 0 0 2 2 2 1 Noc2p family DUF2729 PF10870.8 CCH61467.1 - 0.011 15.6 0.3 0.037 13.9 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2729) DUF5012 PF16404.5 CCH61467.1 - 0.11 12.7 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) Mei5 PF10376.9 CCH61468.1 - 2.8e-29 102.5 24.4 3.6e-29 102.1 24.4 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein Tox-REase-9 PF15650.6 CCH61468.1 - 0.26 11.6 5.6 0.13 12.6 2.3 2.2 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 Tfb2 PF03849.14 CCH61469.1 - 6.1e-140 466.2 6.8 6.1e-140 466.2 6.8 1.5 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CCH61469.1 - 3.3e-21 75.5 0.2 1e-20 73.9 0.2 1.9 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CCH61469.1 - 2.7e-05 24.3 0.0 6.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SLS PF14611.6 CCH61469.1 - 2.1 8.1 6.5 2.5 7.9 3.0 2.8 2 1 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator SPX PF03105.19 CCH61470.1 - 2e-05 24.7 0.1 2e-05 24.7 0.1 3.7 3 1 1 4 4 4 1 SPX domain TFIIE_beta PF02186.15 CCH61470.1 - 1.5 9.1 5.6 3 8.2 0.2 4.1 3 1 0 3 3 3 0 TFIIE beta subunit core domain Rad4 PF03835.15 CCH61471.1 - 1.4e-31 109.2 2.4 1.4e-31 109.2 2.4 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CCH61471.1 - 9.7e-23 80.4 0.0 2.2e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CCH61471.1 - 5.5e-15 54.9 0.0 3.7e-14 52.3 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CCH61471.1 - 6.4e-07 30.2 0.1 6.4e-07 30.2 0.1 3.8 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CCH61471.1 - 1.2e-05 25.7 0.0 4.2e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily ChaC PF04752.12 CCH61472.1 - 5.3e-48 163.4 0.0 6.8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein PhoLip_ATPase_C PF16212.5 CCH61473.1 - 2.5e-76 256.7 29.0 2.5e-76 256.7 29.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCH61473.1 - 1.1e-18 66.7 1.0 1.1e-18 66.7 1.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCH61473.1 - 1.7e-12 47.2 0.0 7.7e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCH61473.1 - 4e-08 33.8 0.9 0.0035 17.7 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCH61473.1 - 5.2e-05 22.9 0.0 0.00019 21.0 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCH61473.1 - 0.0049 16.6 0.2 0.0049 16.6 0.2 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase IMUP PF15761.5 CCH61473.1 - 4.3 8.1 10.8 6.2 7.6 5.0 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein PolyA_pol PF01743.20 CCH61474.1 - 2.3e-32 112.1 0.1 3.7e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CCH61474.1 - 6e-07 29.1 0.0 1.8e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 CCH61474.1 - 0.0021 18.0 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative zf-H2C2_2 PF13465.6 CCH61475.1 - 3.9e-05 23.9 6.5 3.9e-05 23.9 6.5 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH61475.1 - 0.00025 21.6 18.7 0.084 13.8 2.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH61475.1 - 0.0056 17.1 19.5 0.055 13.9 2.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CCH61475.1 - 0.047 14.1 0.2 0.047 14.1 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc_ribbon_9 PF14369.6 CCH61475.1 - 0.3 11.4 5.4 0.95 9.8 5.4 1.9 1 1 0 1 1 1 0 zinc-ribbon zf-C2H2_11 PF16622.5 CCH61475.1 - 0.43 10.4 6.1 1 9.1 6.1 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CCH61475.1 - 1 9.7 10.7 8.5 6.8 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CCH61476.1 - 4.2e-07 30.1 16.4 0.0015 18.9 1.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH61476.1 - 1.8e-06 28.1 5.4 1.8e-06 28.1 5.4 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH61476.1 - 0.00039 21.0 19.1 0.014 16.2 1.5 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH61476.1 - 0.033 14.5 1.7 0.033 14.5 1.7 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 CCH61476.1 - 0.064 13.5 2.1 0.2 11.9 2.1 1.9 1 1 0 1 1 1 0 zinc-ribbon DZR PF12773.7 CCH61476.1 - 0.067 13.2 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_11 PF16622.5 CCH61476.1 - 0.18 11.6 9.7 0.037 13.8 5.2 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_5 PF13719.6 CCH61476.1 - 0.36 10.6 1.3 0.74 9.6 1.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain LicD PF04991.13 CCH61476.1 - 1.4 9.0 16.7 0.29 11.3 11.5 2.4 1 1 1 2 2 2 0 LicD family zf-met PF12874.7 CCH61476.1 - 1.9 9.0 6.2 2.6 8.6 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DEAD_2 PF06733.15 CCH61477.1 - 4e-57 192.7 4.1 7.6e-57 191.8 4.1 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CCH61477.1 - 1.2e-44 152.5 0.0 4.9e-44 150.5 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain HBB PF06777.11 CCH61477.1 - 1.9e-43 148.4 4.4 1.8e-39 135.4 1.3 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CCH61477.1 - 0.00091 19.3 3.6 0.0046 17.0 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Sec63 PF02889.16 CCH61478.1 - 3.8e-129 429.3 17.7 2.4e-73 246.5 1.9 2.9 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 CCH61478.1 - 3.9e-36 124.5 1.0 8.2e-25 87.6 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 CCH61478.1 - 2.1e-17 63.7 14.2 9.5e-16 58.3 0.0 4.3 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 CCH61478.1 - 1.5e-16 60.6 2.3 1.5e-16 60.6 2.3 3.7 3 1 1 4 4 4 1 N-terminal helicase PWI domain Helicase_C PF00271.31 CCH61478.1 - 4.9e-10 39.7 0.1 3.6e-07 30.5 0.0 5.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCH61478.1 - 0.0046 17.2 0.0 0.053 13.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CCH61479.1 - 1.1e-40 139.5 0.2 3.1e-40 138.1 0.2 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CCH61479.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CCH61479.1 - 0.04 13.7 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CCH61479.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 NTPase EndoU_bacteria PF14436.6 CCH61479.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial EndoU nuclease AAA_12 PF13087.6 CCH61480.1 - 4.4e-57 192.9 0.2 4.4e-57 192.9 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCH61480.1 - 1.1e-34 120.5 0.2 4.2e-19 69.4 0.1 5.4 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 CCH61480.1 - 7.6e-11 42.5 0.0 2.6e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCH61480.1 - 2e-09 37.5 0.0 1.8e-08 34.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CCH61480.1 - 3.9e-06 27.3 0.5 0.00043 20.7 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CCH61480.1 - 9.6e-06 25.5 5.5 0.6 9.8 0.0 5.1 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCH61480.1 - 1.7e-05 24.9 0.0 1.7e-05 24.9 0.0 4.8 3 2 0 4 4 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCH61480.1 - 4.6e-05 23.3 0.2 0.00042 20.1 0.2 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 CCH61480.1 - 0.00074 19.0 0.0 0.0052 16.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_26 PF13500.6 CCH61480.1 - 0.002 18.0 0.1 0.0054 16.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CCH61480.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CCH61480.1 - 0.035 14.5 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CCH61480.1 - 0.049 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CCH61480.1 - 0.09 13.1 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-CHY PF05495.12 CCH61480.1 - 0.096 13.2 13.2 0.03 14.8 4.7 2.7 2 0 0 2 2 2 0 CHY zinc finger DUF3316 PF11777.8 CCH61481.1 - 0.085 12.9 3.2 0.25 11.4 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3316) DUF826 PF05696.11 CCH61481.1 - 0.095 12.8 0.3 0.095 12.8 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF826) 14-3-3 PF00244.20 CCH61482.1 - 2.6e-105 350.8 3.5 3.2e-105 350.6 3.5 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CCH61482.1 - 0.04 13.9 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF FRG PF08867.11 CCH61482.1 - 0.076 14.0 0.5 0.24 12.4 0.1 2.0 2 1 0 2 2 2 0 FRG domain Peptidase_C98 PF15499.6 CCH61482.1 - 0.095 12.2 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MitMem_reg PF13012.6 CCH61482.1 - 0.16 12.4 2.1 0.23 11.9 0.3 2.0 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function COPI_assoc PF08507.10 CCH61483.1 - 1.3e-34 119.0 8.6 1.4e-34 118.9 8.6 1.0 1 0 0 1 1 1 1 COPI associated protein CbiQ PF02361.16 CCH61483.1 - 0.021 14.4 8.6 0.04 13.5 0.2 2.0 2 0 0 2 2 2 0 Cobalt transport protein Sec62 PF03839.16 CCH61483.1 - 6.3 6.2 5.8 7.4 6.0 5.3 1.3 1 1 0 1 1 1 0 Translocation protein Sec62 Peptidase_M24 PF00557.24 CCH61484.1 - 1.4e-06 28.2 0.0 2.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF5633 PF18656.1 CCH61484.1 - 0.096 12.6 2.4 0.34 10.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Ste5_C PF12194.8 CCH61485.1 - 3e-71 239.3 2.7 3e-71 239.3 2.7 1.7 2 0 0 2 2 2 1 Protein kinase Fus3-binding zf-RING_2 PF13639.6 CCH61485.1 - 0.014 15.7 5.7 0.032 14.6 5.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CCH61485.1 - 0.02 14.9 1.4 0.054 13.5 1.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 CCH61485.1 - 0.094 12.5 1.3 0.26 11.1 1.3 1.8 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 CCH61485.1 - 0.16 11.6 1.1 0.32 10.7 1.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CCH61485.1 - 0.41 10.5 6.7 1 9.3 6.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH61485.1 - 0.63 10.1 3.4 1.6 8.8 3.4 1.7 1 1 0 1 1 1 0 zinc-RING finger domain PH_10 PF15411.6 CCH61485.1 - 0.81 10.0 3.5 0.42 10.9 0.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Actin PF00022.19 CCH61486.1 - 3.2e-10 39.2 0.0 1.2e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Actin Actin_micro PF17003.5 CCH61486.1 - 0.00021 20.6 0.5 0.00029 20.1 0.5 1.2 1 0 0 1 1 1 1 Putative actin-like family DUF2205 PF10224.9 CCH61488.1 - 5.2e-08 32.8 1.4 5.7e-08 32.6 1.4 1.0 1 0 0 1 1 1 1 Short coiled-coil protein DUP PF00674.18 CCH61489.1 - 1.5e-17 63.6 0.8 1.5e-17 63.6 0.8 2.2 1 1 0 2 2 2 1 DUP family DUP PF00674.18 CCH61490.1 - 5.9e-15 55.3 0.2 1e-14 54.5 0.2 1.5 1 1 0 1 1 1 1 DUP family EMP70 PF02990.16 CCH61491.1 - 6.9e-189 628.8 15.8 1e-188 628.3 15.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 TRAPPC-Trs85 PF12739.7 CCH61492.1 - 1.7e-110 369.8 6.3 1.7e-110 369.8 6.3 1.8 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EntA_Immun PF08951.10 CCH61492.1 - 0.012 15.9 1.3 0.2 12.0 0.1 3.2 2 0 0 2 2 2 0 Enterocin A Immunity Rax2 PF12768.7 CCH61493.1 - 1.6e-52 178.1 6.8 1.6e-52 178.1 6.8 5.5 5 2 0 6 6 6 2 Cortical protein marker for cell polarity HARP PF07443.13 CCH61493.1 - 0.11 12.1 0.1 0.33 10.6 0.1 1.8 1 0 0 1 1 1 0 HepA-related protein (HARP) FGGY_C PF02782.16 CCH61494.1 - 2.9e-49 167.5 0.0 4.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCH61494.1 - 2.5e-20 73.1 0.2 1.9e-18 67.0 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 CCH61494.1 - 0.0032 17.4 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase SMC_N PF02463.19 CCH61495.1 - 1.1e-57 195.0 81.7 2.6e-31 108.8 31.7 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCH61495.1 - 7.6e-22 77.8 0.0 2.7e-21 76.1 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCH61495.1 - 1.1e-07 31.9 32.9 0.00029 20.8 4.0 5.2 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH61495.1 - 5.4e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF5345 PF17280.2 CCH61495.1 - 0.25 11.3 2.7 18 5.4 0.2 3.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Aminotran_1_2 PF00155.21 CCH61498.1 - 3.8e-38 131.6 0.0 5.6e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II SirA PF10747.9 CCH61498.1 - 0.082 13.2 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA DUF2407_C PF13373.6 CCH61499.1 - 1 9.5 5.9 0.4 10.9 2.4 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Ribosomal_L34 PF00468.17 CCH61500.1 - 5.7e-19 67.8 5.8 5.7e-19 67.8 5.8 1.6 1 1 1 2 2 2 1 Ribosomal protein L34 PP-binding PF00550.25 CCH61502.1 - 6.5e-11 42.4 0.4 1e-10 41.8 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CCH61502.1 - 7.3e-07 29.3 1.4 1.5e-06 28.3 1.2 1.7 2 1 0 2 2 2 1 Acyl-carrier DUF1493 PF07377.12 CCH61502.1 - 0.05 14.1 1.1 0.083 13.4 0.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1493) LRR_4 PF12799.7 CCH61503.1 - 2.4e-35 119.9 65.8 8.6e-09 35.5 2.4 7.3 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCH61503.1 - 4.8e-23 80.7 32.5 3.2e-07 30.0 0.3 6.3 5 1 0 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CCH61503.1 - 2.7e-18 66.1 22.5 1.4e-06 28.0 1.1 5.2 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 CCH61503.1 - 7.3e-08 31.9 16.6 0.16 12.1 0.2 7.4 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 CCH61503.1 - 0.00055 20.1 34.7 0.12 13.0 0.1 10.4 10 2 0 10 10 10 2 Leucine Rich Repeat tRNA-synt_2b PF00587.25 CCH61504.1 - 4.8e-46 157.0 0.0 7.2e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCH61504.1 - 2.4e-15 56.4 0.0 4.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.12 CCH61505.1 - 2.1e-85 287.3 23.8 2.3e-85 287.1 23.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DegT_DnrJ_EryC1 PF01041.17 CCH61505.1 - 0.27 10.5 2.7 2.3 7.4 0.2 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family BRAP2 PF07576.12 CCH61505.1 - 0.27 11.5 4.5 0.48 10.7 0.0 3.0 3 0 0 3 3 3 0 BRCA1-associated protein 2 Turandot PF07240.11 CCH61505.1 - 4.3 7.4 6.2 16 5.6 0.2 3.8 3 1 0 3 3 3 0 Stress-inducible humoral factor Turandot DUF1664 PF07889.12 CCH61505.1 - 6 6.9 18.2 0.34 11.0 0.4 4.4 4 2 0 4 4 4 0 Protein of unknown function (DUF1664) G-patch PF01585.23 CCH61506.1 - 1.8e-09 37.3 4.0 4.6e-09 36.0 4.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CCH61506.1 - 0.0019 18.3 1.2 0.0019 18.3 1.2 2.2 2 0 0 2 2 2 1 G-patch domain Sp38 PF07354.12 CCH61506.1 - 0.02 14.4 0.3 0.02 14.4 0.3 2.7 4 0 0 4 4 4 0 Zona-pellucida-binding protein (Sp38) YdiH PF15930.5 CCH61506.1 - 0.044 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function Plasmod_dom_1 PF09715.10 CCH61506.1 - 4.2 7.5 12.8 0.43 10.7 1.4 4.1 4 0 0 4 4 4 0 Plasmodium protein of unknown function (Plasmod_dom_1) CNH PF00780.22 CCH61507.1 - 6.7e-17 62.0 0.2 3e-16 59.8 0.1 2.2 2 1 0 2 2 2 1 CNH domain RhoGEF PF00621.20 CCH61507.1 - 2.1e-07 31.4 0.8 2.1e-07 31.4 0.8 4.2 3 1 0 4 4 4 1 RhoGEF domain PH_5 PF15405.6 CCH61507.1 - 1.8e-06 28.1 0.1 1.8e-06 28.1 0.1 4.5 5 0 0 5 5 5 1 Pleckstrin homology domain Flu_C_NS1 PF03506.13 CCH61507.1 - 0.054 13.5 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Influenza C non-structural protein (NS1) zf-RING_UBOX PF13445.6 CCH61508.1 - 2.1e-06 27.6 6.8 5.3e-06 26.3 6.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCH61508.1 - 3.1e-06 27.0 5.8 8.8e-06 25.6 5.8 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CCH61508.1 - 5.8e-06 26.5 5.5 1.2e-05 25.5 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCH61508.1 - 1.9e-05 24.4 6.7 4.9e-05 23.1 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCH61508.1 - 0.00022 21.0 5.5 0.00088 19.1 5.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH61508.1 - 0.0011 19.1 6.7 0.003 17.7 6.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CCH61508.1 - 0.0094 15.8 3.8 0.0094 15.8 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH61508.1 - 0.079 12.8 12.2 6.5 6.7 0.1 3.0 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF1676 PF07898.13 CCH61508.1 - 0.64 10.0 7.2 0.064 13.3 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) zf-rbx1 PF12678.7 CCH61508.1 - 1.2 9.5 5.3 4.8 7.6 5.3 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain IBR PF01485.21 CCH61508.1 - 8.6 6.7 7.0 31 4.9 0.2 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1899 PF08953.11 CCH61509.1 - 1.3e-26 92.3 0.2 2.8e-26 91.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CCH61509.1 - 6.3e-17 61.7 7.0 4.8e-05 24.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_4 PF16300.5 CCH61509.1 - 1.3e-15 57.0 0.1 2.5e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 CCH61509.1 - 6.2e-05 23.2 0.1 0.0015 18.8 0.1 3.2 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain V-SNARE PF05008.15 CCH61509.1 - 0.023 15.1 1.8 0.041 14.3 1.8 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus IMPDH PF00478.25 CCH61511.1 - 2.8e-133 444.2 3.5 3.3e-133 444.0 3.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CCH61511.1 - 1.5e-14 54.1 0.0 5.6e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CCH61511.1 - 1.3e-06 27.7 3.2 2.9e-06 26.6 3.1 1.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CCH61511.1 - 3.9e-05 23.2 2.6 0.00081 18.9 2.6 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein NMO PF03060.15 CCH61511.1 - 0.00035 20.1 8.3 0.044 13.2 7.2 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase Aldolase PF01081.19 CCH61511.1 - 0.0018 17.7 0.8 0.011 15.2 0.2 2.2 2 0 0 2 2 2 1 KDPG and KHG aldolase NanE PF04131.14 CCH61511.1 - 0.0055 15.9 0.4 0.012 14.8 0.4 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase YpsA PF06908.11 CCH61511.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 YspA SLOG family PK PF00224.21 CCH61511.1 - 0.03 13.2 0.2 0.63 8.9 0.0 2.5 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain ThiG PF05690.14 CCH61511.1 - 0.095 12.0 2.6 0.11 11.7 1.0 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Metallophos PF00149.28 CCH61512.1 - 7.8e-36 124.5 0.1 1.3e-35 123.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hid1 PF12722.7 CCH61513.1 - 6e-37 127.2 89.3 5.6e-29 100.9 18.5 6.2 4 2 2 7 7 7 5 High-temperature-induced dauer-formation protein cNMP_binding PF00027.29 CCH61514.1 - 1e-25 89.6 0.3 8.5e-13 48.2 0.0 6.3 6 1 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CCH61514.1 - 3.2e-18 66.7 0.8 1.3e-11 45.1 0.6 3.2 3 0 0 3 3 3 2 Patatin-like phospholipase LSM PF01423.22 CCH61515.1 - 2.1e-18 65.8 0.1 2.4e-18 65.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CCH61515.1 - 0.01 16.0 0.0 0.033 14.3 0.0 1.7 1 1 1 2 2 2 1 RimP C-terminal SH3 domain MRP-L47 PF06984.13 CCH61516.1 - 2.9e-23 81.8 0.5 2.9e-23 81.8 0.5 2.1 3 0 0 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF1509 PF07420.11 CCH61516.1 - 0.029 13.3 0.6 0.045 12.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) OGG_N PF07934.12 CCH61517.1 - 3.1e-19 69.2 2.4 6.2e-19 68.3 2.4 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CCH61517.1 - 7.5e-16 58.5 0.0 3.1e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIF1 PF05970.14 CCH61518.1 - 2.1e-72 244.3 1.9 8e-54 183.2 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CCH61518.1 - 4.5e-17 62.4 0.0 1.9e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCH61518.1 - 1.1e-09 38.8 0.0 2.3e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCH61518.1 - 1.1e-05 25.7 0.1 5.2e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCH61518.1 - 0.0043 16.6 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CCH61518.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 CCH61518.1 - 0.0073 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_32 PF13654.6 CCH61518.1 - 0.0098 14.7 0.1 0.0098 14.7 0.1 2.1 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 CCH61518.1 - 0.031 14.0 4.1 2.3 7.9 0.1 3.3 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CCH61518.1 - 0.044 12.8 0.0 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CCH61518.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Helicase_RecD PF05127.14 CCH61518.1 - 0.28 11.0 2.7 0.35 10.7 0.2 2.5 2 1 0 2 2 2 0 Helicase THOC7 PF05615.13 CCH61519.1 - 8.7e-10 39.0 6.5 8.7e-10 39.0 6.5 2.8 3 0 0 3 3 3 1 Tho complex subunit 7 PI_PP_I PF18363.1 CCH61519.1 - 0.25 11.5 4.3 0.14 12.4 1.3 2.2 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Myb_DNA-bind_3 PF12776.7 CCH61519.1 - 1.3 10.1 12.7 0.16 13.0 1.8 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Prominin PF05478.11 CCH61519.1 - 7.8 4.3 17.0 1.4 6.8 8.1 2.3 1 1 0 2 2 2 0 Prominin Ribosomal_S3Ae PF01015.18 CCH61520.1 - 6.2e-86 287.1 5.1 7.3e-86 286.9 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 CCH61520.1 - 0.022 14.4 0.0 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region AAA_lid_10 PF17872.1 CCH61521.1 - 1.9e-44 149.8 0.1 1.9e-44 149.8 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CCH61521.1 - 7.6e-21 74.9 0.0 9.6e-20 71.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH61521.1 - 7.4e-09 36.2 0.0 4.9e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain BAH PF01426.18 CCH61521.1 - 1.3e-07 31.5 0.1 3.3e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.6 CCH61521.1 - 4.1e-07 30.3 0.4 4.7e-06 26.9 0.0 2.8 4 0 0 4 4 4 1 AAA domain ATPase_2 PF01637.18 CCH61521.1 - 2.4e-05 24.4 14.8 0.00012 22.1 0.2 4.2 4 1 0 4 4 4 2 ATPase domain predominantly from Archaea NACHT PF05729.12 CCH61521.1 - 0.0057 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 CCH61521.1 - 0.025 14.9 0.0 0.081 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH61521.1 - 0.041 14.4 0.0 0.21 12.1 0.0 2.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CCH61521.1 - 0.46 10.5 4.4 0.67 9.9 0.0 3.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Dor1 PF04124.12 CCH61523.1 - 2.6e-42 144.7 7.0 4.7e-42 143.9 7.0 1.3 1 0 0 1 1 1 1 Dor1-like family Clathrin PF00637.20 CCH61523.1 - 0.0043 16.9 0.3 0.068 13.0 0.0 2.8 2 1 1 3 3 3 1 Region in Clathrin and VPS TPR_7 PF13176.6 CCH61523.1 - 0.074 13.1 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SPATA3 PF15662.5 CCH61523.1 - 6.8 7.3 9.3 12 6.5 9.3 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family C2 PF00168.30 CCH61524.1 - 2.2e-58 194.9 0.2 2.6e-19 69.4 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 CCH61524.1 - 0.00049 19.6 0.2 0.0071 15.8 0.2 2.4 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain Cornifin PF02389.15 CCH61524.1 - 0.11 12.7 13.6 0.26 11.5 13.6 1.6 1 0 0 1 1 1 0 Cornifin (SPRR) family Piwi PF02171.17 CCH61525.1 - 7.9e-64 215.8 0.3 1.3e-63 215.1 0.3 1.3 1 0 0 1 1 1 1 Piwi domain AGO_N PF18236.1 CCH61525.1 - 6.9e-58 194.2 0.0 6.9e-58 194.2 0.0 5.9 2 1 2 4 4 4 1 Argonaute N domain Ago_N_1 PF18351.1 CCH61525.1 - 3e-45 152.6 0.5 5.6e-44 148.5 0.3 3.3 2 0 0 2 2 2 1 Fungal Argonaute N-terminal domain HMG-CoA_red PF00368.18 CCH61526.1 - 2.1e-140 467.9 0.1 3.2e-140 467.3 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 CCH61526.1 - 2.4e-47 160.7 0.6 2.4e-47 160.7 0.6 2.5 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CCH61526.1 - 6.1e-07 29.4 6.2 6.1e-07 29.4 6.2 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SR-25 PF10500.9 CCH61526.1 - 0.23 11.1 14.6 0.38 10.3 14.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4337 PF14235.6 CCH61526.1 - 5.2 7.2 5.5 9.9 6.3 5.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GEMIN8 PF15348.6 CCH61526.1 - 9.8 6.4 10.0 15 5.8 10.0 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Zn_clus PF00172.18 CCH61527.1 - 7.6e-07 29.1 8.1 1.8e-06 28.0 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ENTH PF01417.20 CCH61528.1 - 1.9e-41 141.0 0.0 3.9e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CCH61528.1 - 0.0002 20.5 0.0 0.00042 19.4 0.0 1.5 1 0 0 1 1 1 1 ANTH domain DUF4070 PF13282.6 CCH61528.1 - 0.13 12.4 0.3 0.26 11.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) zf-C2H2 PF00096.26 CCH61529.1 - 4.3e-05 23.7 16.5 0.00046 20.5 1.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH61529.1 - 6.6e-05 23.2 7.7 0.00032 21.0 3.9 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH61529.1 - 0.00089 19.9 12.6 0.0081 16.9 1.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger ATP-synt_J PF04911.12 CCH61530.1 - 1.3e-23 82.3 0.4 1.4e-23 82.2 0.4 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.20 CCH61531.1 - 2.4e-05 23.1 0.2 0.0004 19.0 0.1 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Ctf8 PF09696.10 CCH61532.1 - 3.9e-21 75.9 1.0 6.3e-19 68.7 1.0 2.1 1 1 0 1 1 1 1 Ctf8 Pox_I6 PF04595.13 CCH61532.1 - 0.074 12.0 0.0 0.094 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family zinc_ribbon_10 PF10058.9 CCH61533.1 - 7.1e-11 41.7 1.9 1.1e-10 41.0 1.9 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein HlyD_2 PF12700.7 CCH61533.1 - 0.0047 15.7 3.9 0.0047 15.7 3.9 1.7 2 0 0 2 2 2 1 HlyD family secretion protein Phage_holin_6_1 PF09682.10 CCH61533.1 - 0.02 15.3 0.3 0.041 14.3 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Vps23_core PF09454.10 CCH61533.1 - 0.022 14.7 0.2 0.15 12.0 0.2 2.1 2 0 0 2 2 2 0 Vps23 core domain Lip_prot_lig_C PF10437.9 CCH61533.1 - 0.26 11.3 3.5 1.9 8.5 1.1 2.3 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Vps36-NZF-N PF16988.5 CCH61533.1 - 0.3 10.5 0.1 0.3 10.5 0.1 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Babuvirus_MP PF07234.11 CCH61533.1 - 0.33 11.1 3.3 0.32 11.2 2.3 1.4 1 1 0 1 1 1 0 Movement and RNA silencing protein SlyX PF04102.12 CCH61533.1 - 0.54 10.9 2.8 0.89 10.2 1.0 2.1 2 0 0 2 2 2 0 SlyX Prefoldin PF02996.17 CCH61533.1 - 0.73 9.8 11.6 0.62 10.0 3.8 2.4 3 0 0 3 3 3 0 Prefoldin subunit KxDL PF10241.9 CCH61533.1 - 2.5 8.5 7.7 0.24 11.7 0.8 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF2207 PF09972.9 CCH61533.1 - 4.4 6.0 16.5 0.087 11.6 2.4 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) NAC PF01849.18 CCH61534.1 - 2.4e-20 72.3 0.3 4e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 NAC domain SPT6_acidic PF14632.6 CCH61534.1 - 0.064 13.8 0.2 0.12 13.0 0.2 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 IBN_N PF03810.19 CCH61535.1 - 5.8e-19 67.8 0.1 4.8e-18 64.9 0.1 2.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain RIX1 PF08167.12 CCH61535.1 - 0.0097 15.7 0.9 0.89 9.3 0.7 3.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis putAbiC PF16872.5 CCH61535.1 - 7 7.4 10.1 16 6.2 1.9 4.5 2 1 1 3 3 3 0 Putative phage abortive infection protein Pribosyltran PF00156.27 CCH61536.1 - 1.4e-09 37.7 0.0 2.5e-09 36.9 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Trimer_CC PF08954.11 CCH61536.1 - 0.028 14.0 0.7 0.046 13.3 0.7 1.3 1 0 0 1 1 1 0 Trimerisation motif RIX1 PF08167.12 CCH61537.1 - 3.1e-50 170.5 4.5 3.1e-50 170.5 4.5 2.5 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis IML1 PF12257.8 CCH61538.1 - 1.9e-104 348.8 3.0 1.9e-104 348.8 3.0 2.1 3 0 0 3 3 3 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CCH61538.1 - 4.7e-24 84.2 0.4 1.1e-23 83.1 0.4 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.19 CCH61539.1 - 5.1e-53 179.5 0.0 6.9e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CCH61539.1 - 9.3e-21 74.7 0.0 1.7e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1889 PF08986.10 CCH61539.1 - 0.071 13.5 0.0 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) Hydrolase_6 PF13344.6 CCH61539.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HECT_2 PF09814.9 CCH61541.1 - 9.9e-75 251.7 0.2 1.1e-74 251.6 0.2 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 CCH61541.1 - 0.037 14.2 0.8 0.12 12.6 0.8 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-P11 PF03854.14 CCH61541.1 - 0.21 11.3 2.7 0.2 11.4 0.3 2.1 2 0 0 2 2 2 0 P-11 zinc finger DHHA2 PF02833.14 CCH61542.1 - 6.1e-29 101.1 0.4 9.8e-29 100.4 0.4 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CCH61542.1 - 2.2e-09 37.5 0.0 5.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 DHH family Thiol_cytolys_C PF17440.2 CCH61542.1 - 0.043 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Thiol-activated cytolysin beta sandwich domain 5_nucleotid_C PF02872.18 CCH61543.1 - 0.0021 18.3 0.1 0.014 15.6 0.0 2.3 2 1 1 3 3 3 1 5'-nucleotidase, C-terminal domain Ribosomal_S4e PF00900.20 CCH61544.1 - 6.4e-39 131.7 1.5 2.1e-37 126.9 1.1 2.3 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CCH61544.1 - 9e-26 89.3 0.0 1.9e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CCH61544.1 - 3.9e-19 68.5 6.9 1.1e-18 67.0 6.9 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CCH61544.1 - 8.1e-09 35.1 0.8 1.3e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CCH61544.1 - 4.1e-06 26.5 1.8 4.1e-06 26.5 1.8 3.3 4 0 0 4 4 4 1 KOW motif Sipho_tail PF05709.11 CCH61544.1 - 0.078 12.4 0.2 0.18 11.2 0.2 1.6 1 1 0 1 1 1 0 Phage tail protein Glyco_hydro_47 PF01532.20 CCH61545.1 - 2.4e-108 363.0 0.4 3.3e-108 362.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 CCH61546.1 - 1.6e-59 201.4 0.0 2.6e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61546.1 - 1.9e-31 109.3 0.0 2.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH61546.1 - 0.00089 18.3 1.0 0.00089 18.3 1.0 2.1 2 1 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 CCH61546.1 - 0.089 12.1 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like HSF_DNA-bind PF00447.17 CCH61547.1 - 1e-24 86.9 3.8 1e-24 86.9 3.8 2.9 3 1 0 3 3 3 1 HSF-type DNA-binding Response_reg PF00072.24 CCH61547.1 - 2.2e-12 47.1 0.6 3.2e-11 43.4 0.1 2.9 3 0 0 3 3 3 1 Response regulator receiver domain Ets PF00178.22 CCH61547.1 - 0.03 14.8 1.8 0.59 10.6 0.0 3.2 3 0 0 3 3 3 0 Ets-domain SET PF00856.28 CCH61548.1 - 2.1e-10 41.3 5.4 2.5e-10 41.0 3.0 2.4 2 1 0 2 2 2 1 SET domain Myticin-prepro PF10690.9 CCH61548.1 - 0.2 11.9 2.9 3.6 7.9 0.4 2.6 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Aminotran_4 PF01063.19 CCH61550.1 - 6e-36 124.4 0.0 8e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV DnaJ_CXXCXGXG PF00684.19 CCH61551.1 - 9.4 6.7 14.8 0.15 12.5 4.6 2.6 2 1 0 2 2 2 0 DnaJ central domain Zn_clus PF00172.18 CCH61552.1 - 2.5e-07 30.7 8.4 5e-07 29.7 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 CCH61553.1 - 1.8e-60 204.7 0.1 2.1e-60 204.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Torsin PF06309.11 CCH61553.1 - 0.14 12.3 0.2 1 9.5 0.2 2.1 1 1 1 2 2 2 0 Torsin SPOB_a PF14689.6 CCH61554.1 - 0.029 14.1 0.2 0.075 12.8 0.1 1.8 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain EzrA PF06160.12 CCH61554.1 - 0.082 11.1 0.6 0.13 10.5 0.2 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 CCH61554.1 - 0.088 13.0 0.5 0.43 10.8 0.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BORCS6 PF10157.9 CCH61554.1 - 0.089 13.0 3.1 0.42 10.8 0.1 2.2 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 DNA_Packaging PF11053.8 CCH61554.1 - 0.097 12.5 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Terminase DNA packaging enzyme DUF3533 PF12051.8 CCH61555.1 - 2.7e-92 309.6 21.8 2.7e-92 309.6 21.8 1.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 CCH61555.1 - 0.037 13.9 0.2 0.037 13.9 0.2 4.1 6 1 1 7 7 7 0 CDR ABC transporter DUF3533 PF12051.8 CCH61557.1 - 2.3e-88 296.7 24.2 2.3e-88 296.7 24.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) CitMHS PF03600.16 CCH61557.1 - 0.055 12.6 5.5 0.1 11.8 5.5 1.4 1 0 0 1 1 1 0 Citrate transporter DUF1676 PF07898.13 CCH61557.1 - 0.35 10.9 3.4 4 7.5 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) RRM_1 PF00076.22 CCH61558.1 - 0.006 16.4 0.1 1.3 8.9 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NGP1NT PF08153.12 CCH61559.1 - 6.2e-51 171.9 0.2 1.2e-50 171.0 0.2 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CCH61559.1 - 8.4e-18 64.5 0.0 1.5e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCH61559.1 - 1.6e-05 24.4 0.0 8.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CCH61559.1 - 0.0014 18.1 0.1 0.25 10.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCH61559.1 - 0.0039 17.1 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CCH61559.1 - 0.0049 16.4 0.0 0.47 10.0 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCH61559.1 - 0.014 15.4 5.4 0.81 9.7 0.0 3.7 3 1 1 4 4 4 0 Dynamin family SusD-like_3 PF14322.6 CCH61559.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane CAF1 PF04857.20 CCH61560.1 - 2.2e-11 43.5 13.7 1e-05 24.9 0.0 3.2 2 1 1 3 3 3 2 CAF1 family ribonuclease TERB2 PF15101.6 CCH61560.1 - 0.041 14.0 9.8 0.096 12.7 9.8 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDHD PF02862.17 CCH61560.1 - 0.045 13.9 7.6 0.069 13.3 7.6 1.4 1 0 0 1 1 1 0 DDHD domain Exonuc_VII_L PF02601.15 CCH61560.1 - 0.065 12.8 12.2 0.094 12.3 12.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR1 PF08505.10 CCH61560.1 - 0.21 11.9 28.1 0.42 10.9 28.1 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PepSY_TM PF03929.16 CCH61560.1 - 1.3 8.6 4.9 5.9 6.5 3.9 2.2 2 0 0 2 2 2 0 PepSY-associated TM region Tristanin_u2 PF16638.5 CCH61560.1 - 2.5 9.0 12.6 9.6 7.0 12.6 2.0 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Membralin PF09746.9 CCH61560.1 - 5.2 6.0 8.9 7.9 5.4 8.9 1.2 1 0 0 1 1 1 0 Tumour-associated protein CDK5_activator PF03261.15 CCH61560.1 - 5.6 6.4 23.5 9.5 5.6 23.5 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Neur_chan_memb PF02932.16 CCH61560.1 - 7 6.6 11.8 12 5.8 11.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 CCH61560.1 - 7.5 6.6 11.6 16 5.6 11.6 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S49_N PF08496.10 CCH61560.1 - 8.3 6.5 11.1 19 5.3 11.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_23 PF13476.6 CCH61560.1 - 8.6 6.8 20.2 1.7 9.1 16.0 2.1 2 0 0 2 2 2 0 AAA domain NTF2 PF02136.20 CCH61561.1 - 2.5e-17 63.5 2.3 3.4e-17 63.1 0.0 2.2 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Y_phosphatase2 PF03162.13 CCH61562.1 - 5.2e-35 120.5 3.9 2.6e-24 85.6 0.4 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Sacchrp_dh_C PF16653.5 CCH61563.1 - 2.9e-95 319.4 0.0 1.9e-94 316.7 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CCH61563.1 - 1.9e-22 79.9 0.2 2.9e-22 79.3 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CCH61563.1 - 2e-08 34.4 0.1 4.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CCH61563.1 - 2.4e-07 30.8 0.1 3.8e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 CCH61563.1 - 6.8e-05 23.4 0.1 0.00014 22.4 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 CCH61563.1 - 0.0015 18.1 0.1 0.005 16.4 0.1 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_3 PF03447.16 CCH61563.1 - 0.0033 18.1 0.2 0.0068 17.1 0.2 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCH61563.1 - 0.029 13.7 0.4 0.066 12.5 0.3 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 CCH61563.1 - 0.15 12.9 0.0 0.29 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Mso1_Sec1_bdg PF14475.6 CCH61564.1 - 2.7e-15 55.7 0.0 6.8e-15 54.4 0.0 1.7 1 0 0 1 1 1 1 Sec1-binding region of Mso1 CDC50 PF03381.15 CCH61565.1 - 4e-90 302.1 3.7 5.1e-90 301.8 3.7 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Not1 PF04054.15 CCH61566.1 - 7.1e-124 413.5 9.4 7.1e-124 413.5 9.4 3.4 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CCH61566.1 - 6e-85 284.2 6.8 3.4e-84 281.7 6.8 2.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT_N PF16419.5 CCH61566.1 - 1.2e-81 273.7 11.8 1.2e-81 273.7 11.8 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 CCH61566.1 - 1.2e-41 142.0 0.1 7.1e-41 139.5 0.1 2.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CCH61566.1 - 8.9e-41 139.2 4.4 8.9e-41 139.2 4.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CCH61566.1 - 3.2e-14 53.3 0.6 3.2e-14 53.3 0.6 3.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat MutS_V PF00488.21 CCH61567.1 - 4.1e-62 209.6 0.2 1.6e-61 207.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CCH61567.1 - 3.1e-31 109.1 1.2 3.1e-31 109.1 1.2 2.8 4 1 0 4 4 4 1 MutS domain III MutS_I PF01624.20 CCH61567.1 - 6.9e-29 100.4 0.1 1.7e-28 99.1 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CCH61567.1 - 2e-08 34.5 0.8 1.2e-07 31.9 0.8 2.4 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CCH61567.1 - 8.6e-05 22.8 2.9 0.00012 22.4 0.4 2.6 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.6 CCH61567.1 - 0.14 12.2 0.0 0.14 12.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 CCH61568.1 - 1e-76 257.8 0.1 2.8e-76 256.4 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61568.1 - 2.8e-31 108.7 0.1 6.6e-30 104.2 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH61568.1 - 1.1e-06 28.1 0.1 0.00055 19.3 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 CCH61568.1 - 0.083 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF866 PF05907.13 CCH61570.1 - 6.6e-42 143.0 5.8 7.8e-42 142.8 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) RNA_pol_Rpb2_7 PF04560.20 CCH61570.1 - 0.11 12.9 0.5 0.24 11.8 0.4 1.7 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 7 DUF3795 PF12675.7 CCH61570.1 - 0.15 12.5 4.2 4.4 7.8 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) Elf1 PF05129.13 CCH61570.1 - 5.3 7.2 9.3 9.3 6.4 0.8 3.1 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Flocculin_t3 PF13928.6 CCH61571.1 - 2e-11 44.2 46.9 1.9e-07 31.4 18.5 20.2 7 6 8 15 15 15 3 Flocculin type 3 repeat Cofilin_ADF PF00241.20 CCH61572.1 - 2.1e-22 79.2 0.0 6.1e-22 77.7 0.0 1.8 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 CCH61572.1 - 3.7e-17 61.7 0.6 1.1e-16 60.1 0.6 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH61572.1 - 1.7e-13 50.2 0.2 3.4e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH61572.1 - 3e-07 30.0 0.1 8e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Trehalase PF01204.18 CCH61573.1 - 1.4e-188 628.0 0.0 1.7e-188 627.7 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CCH61573.1 - 6e-16 57.9 0.4 1.1e-15 57.0 0.4 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain OCRE PF17780.1 CCH61573.1 - 0.03 14.3 0.2 0.093 12.8 0.2 1.8 1 0 0 1 1 1 0 OCRE domain Thiamine_BP PF01910.17 CCH61574.1 - 5e-28 96.8 0.0 5.7e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein WD40_3 PF15911.5 CCH61574.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 WD domain, G-beta repeat Histone PF00125.24 CCH61575.1 - 3.3e-20 72.8 3.1 4.5e-20 72.4 3.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCH61575.1 - 7.3e-06 26.2 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCH61575.1 - 0.0015 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CCH61575.1 - 0.0065 16.7 0.0 0.0092 16.2 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 CCH61575.1 - 0.046 13.7 0.4 0.056 13.5 0.4 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 CCH61576.1 - 2e-21 75.4 1.6 3.3e-21 74.7 1.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCH61576.1 - 6.7e-18 65.3 0.0 9.3e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCH61576.1 - 8.8e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DRIM PF07539.12 CCH61577.1 - 4.9e-162 540.5 7.7 4.9e-162 540.5 7.7 4.9 6 0 0 6 6 6 2 Down-regulated in metastasis UME PF08064.13 CCH61577.1 - 1.6 8.6 4.7 4.6 7.2 0.1 4.4 5 0 0 5 5 5 0 UME (NUC010) domain Rad21_Rec8_N PF04825.13 CCH61578.1 - 5.9e-22 77.9 0.3 1.3e-21 76.8 0.3 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CCH61578.1 - 1e-09 37.6 0.0 2.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Med2 PF11214.8 CCH61579.1 - 4.6e-34 116.6 10.1 4.6e-34 116.6 10.1 4.9 3 1 0 3 3 3 1 Mediator complex subunit 2 Utp14 PF04615.13 CCH61579.1 - 3 6.3 52.6 4 5.9 52.6 1.1 1 0 0 1 1 1 0 Utp14 protein COX6A PF02046.15 CCH61580.1 - 1.1e-36 125.7 1.0 1.3e-36 125.5 0.7 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa zf-C2H2 PF00096.26 CCH61581.1 - 2.5e-12 46.5 14.4 4.9e-06 26.7 2.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCH61581.1 - 5.3e-08 32.9 12.2 0.0013 18.9 4.4 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCH61581.1 - 1.8e-07 31.4 11.5 0.0024 18.6 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCH61581.1 - 1.6e-05 24.8 9.7 0.0034 17.3 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCH61581.1 - 1.7e-05 25.0 16.1 1.9e-05 24.9 4.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 CCH61581.1 - 7.6e-05 22.9 5.0 0.00013 22.2 5.0 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CCH61581.1 - 0.00016 21.9 9.5 0.11 12.9 4.1 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 CCH61581.1 - 0.00073 19.1 3.1 0.0022 17.6 0.6 2.4 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 CCH61581.1 - 0.16 12.3 10.9 4.7 7.6 2.8 3.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 CCH61581.1 - 0.2 11.3 0.1 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 CCH61581.1 - 0.21 11.5 9.5 1.4 8.9 3.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2HE PF16278.5 CCH61581.1 - 3.3 8.2 8.7 3.9e+02 1.6 8.7 3.2 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger PUF PF00806.19 CCH61582.1 - 3.1e-40 133.6 28.9 1.1e-05 24.9 0.1 8.9 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MT-A70 PF05063.14 CCH61583.1 - 1.3e-55 187.9 0.2 2.9e-55 186.8 0.2 1.6 1 0 0 1 1 1 1 MT-A70 HEAT_EZ PF13513.6 CCH61585.1 - 9.7e-31 105.8 8.3 0.0026 18.2 0.0 14.4 13 1 1 14 14 14 7 HEAT-like repeat HEAT_2 PF13646.6 CCH61585.1 - 4.3e-27 94.3 10.2 0.00087 19.6 0.2 13.2 10 2 4 14 14 14 7 HEAT repeats HEAT PF02985.22 CCH61585.1 - 2.8e-26 89.3 14.1 0.011 15.9 0.0 17.7 22 0 0 22 22 22 5 HEAT repeat Gcn1_N PF12074.8 CCH61585.1 - 2e-21 76.7 7.2 4.6e-12 45.9 0.0 3.8 5 0 0 5 5 5 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Cnd1 PF12717.7 CCH61585.1 - 1.2e-12 48.2 12.6 0.18 11.8 0.0 10.4 6 2 2 9 9 9 5 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCH61585.1 - 3.7e-10 40.3 0.5 3.5 8.3 0.0 8.3 7 1 1 8 8 8 2 Vacuolar 14 Fab1-binding region Phage_Coat_Gp8 PF05371.12 CCH61585.1 - 0.05 13.4 0.0 0.65 9.8 0.0 2.6 2 0 0 2 2 2 0 Phage major coat protein, Gp8 QueF PF14489.6 CCH61585.1 - 0.075 13.2 0.0 0.81 9.9 0.0 2.8 2 0 0 2 2 2 0 QueF-like protein RTP1_C1 PF10363.9 CCH61585.1 - 0.54 10.4 7.1 52 4.1 0.2 6.5 7 0 0 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Kelch_4 PF13418.6 CCH61586.1 - 5.9e-12 45.4 4.5 2e-05 24.5 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CCH61586.1 - 2.3e-11 43.5 1.5 1.1e-06 28.7 0.1 4.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 CCH61586.1 - 3.1e-07 29.8 0.7 0.0072 15.9 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CCH61586.1 - 1.7e-06 27.8 0.7 0.0078 16.2 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CCH61586.1 - 4.4e-05 23.4 0.0 0.001 19.0 0.0 3.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CCH61586.1 - 0.0059 16.9 0.8 3 8.3 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Yip1 PF04893.17 CCH61587.1 - 6.1e-07 29.3 8.7 8e-07 28.9 8.7 1.2 1 0 0 1 1 1 1 Yip1 domain Lgl_C PF08596.10 CCH61588.1 - 8.7e-118 393.4 0.7 1.8e-117 392.4 0.1 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CCH61588.1 - 1.3e-07 31.8 0.2 0.094 13.0 0.0 5.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH61588.1 - 1.3e-06 29.0 3.3 1.2 10.2 0.0 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 CCH61588.1 - 0.054 12.1 0.2 0.28 9.8 0.0 2.2 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Actin PF00022.19 CCH61589.1 - 8.1e-49 166.3 0.3 1.1e-34 119.8 0.0 2.3 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CCH61589.1 - 0.0031 16.4 0.1 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Sugar_tr PF00083.24 CCH61591.1 - 5.4e-06 25.5 5.0 5.4e-06 25.5 5.0 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CCH61591.1 - 1.5e-05 23.7 14.2 1.5e-05 23.7 14.2 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CCH61591.1 - 2.8e-05 23.2 46.4 0.00044 19.3 43.2 3.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ARD PF03079.14 CCH61591.1 - 0.059 13.6 5.1 0.13 12.4 5.1 1.5 1 0 0 1 1 1 0 ARD/ARD' family DUF3452 PF11934.8 CCH61591.1 - 0.09 12.3 0.2 0.26 10.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) TIP41 PF04176.13 CCH61592.1 - 3.7e-65 218.6 3.0 5.6e-65 218.0 3.0 1.3 1 0 0 1 1 1 1 TIP41-like family BIR PF00653.21 CCH61593.1 - 4.5e-09 36.8 0.3 0.0059 17.2 0.0 2.8 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain UbiA PF01040.18 CCH61595.1 - 3.6e-42 144.4 11.6 4.8e-42 144.0 11.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family WD40 PF00400.32 CCH61596.1 - 3.4e-53 176.4 16.0 1.9e-08 34.8 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CCH61596.1 - 3.6e-28 97.7 11.7 1.2e-27 96.0 10.7 2.2 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CCH61596.1 - 1e-17 64.2 1.5 0.00058 20.1 0.0 6.4 3 1 3 7 7 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCH61596.1 - 7.7e-07 28.1 11.9 0.14 10.7 0.1 4.4 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCH61596.1 - 1.3e-06 27.6 0.2 0.22 10.4 0.0 4.3 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCH61596.1 - 1.4e-05 24.6 4.8 1.5 8.1 0.0 5.2 4 1 1 5 5 5 2 WD40-like domain Trypan_PARP PF05887.11 CCH61596.1 - 0.00015 21.8 15.3 0.00028 20.9 15.3 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Frtz PF11768.8 CCH61596.1 - 0.0015 17.0 0.8 0.085 11.2 0.1 3.5 2 2 1 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 CCH61596.1 - 0.0047 16.8 0.3 38 4.4 0.0 4.7 4 1 1 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 CCH61596.1 - 0.032 13.8 3.7 0.055 13.0 2.0 2.2 1 1 2 3 3 3 0 PQQ-like domain CCDC-167 PF15188.6 CCH61596.1 - 0.1 12.9 5.6 0.19 12.1 5.2 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Neisseria_TspB PF05616.13 CCH61596.1 - 0.29 9.6 14.5 0.47 8.9 14.5 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Csm1_N PF18504.1 CCH61597.1 - 7e-24 84.0 8.4 1.1e-23 83.3 8.4 1.3 1 0 0 1 1 1 1 Csm1 N-terminal domain Csm1 PF12539.8 CCH61597.1 - 4.5e-21 75.3 0.2 8.7e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF16 PF01519.16 CCH61597.1 - 0.00047 20.6 2.2 0.0009 19.7 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 RasGAP_C PF03836.15 CCH61597.1 - 0.0038 17.4 0.9 0.0047 17.1 0.9 1.3 1 0 0 1 1 1 1 RasGAP C-terminus Syntaxin-6_N PF09177.11 CCH61597.1 - 0.075 13.6 1.2 0.12 13.0 1.2 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal MPS2 PF17060.5 CCH61597.1 - 0.093 12.0 5.2 0.14 11.4 5.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 zf-LYAR PF08790.11 CCH61598.1 - 5.2e-13 48.7 9.4 9.7e-13 47.8 9.4 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 CCH61598.1 - 0.0031 17.8 4.6 0.097 13.0 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 CCH61598.1 - 0.03 13.9 1.3 5.8 6.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger XPA_N PF01286.18 CCH61598.1 - 0.033 14.2 4.2 0.74 9.9 0.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_4 PF13894.6 CCH61598.1 - 0.042 14.7 6.2 0.33 11.9 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TMEM214 PF10151.9 CCH61598.1 - 0.069 11.6 5.8 0.081 11.4 5.8 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator zf-C2H2 PF00096.26 CCH61598.1 - 0.33 11.5 7.0 0.35 11.4 1.8 2.5 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 CCH61598.1 - 0.86 10.1 5.5 2 8.9 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-ACC PF17848.1 CCH61598.1 - 6 7.0 8.1 1.3 9.2 3.8 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Prenyltransf PF01255.19 CCH61599.1 - 6.1e-76 254.8 0.1 7.3e-76 254.6 0.1 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PNKP_ligase PF16542.5 CCH61599.1 - 0.035 13.6 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain NAGidase PF07555.13 CCH61599.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase TMEMspv1-c74-12 PF11044.8 CCH61599.1 - 0.65 10.0 4.0 12 5.9 0.2 3.4 4 0 0 4 4 4 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein polyprenyl_synt PF00348.17 CCH61600.1 - 3.1e-66 223.0 0.0 1.6e-59 201.1 0.0 3.0 2 1 0 2 2 2 2 Polyprenyl synthetase BRE1 PF08647.11 CCH61601.1 - 0.22 11.6 4.6 0.11 12.5 0.5 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Aldedh PF00171.22 CCH61602.1 - 3.6e-160 533.5 0.0 4e-160 533.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CCH61602.1 - 0.022 14.2 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) RCR PF12273.8 CCH61604.1 - 0.00092 19.9 0.0 0.0018 18.9 0.0 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Topo_C_assoc PF14370.6 CCH61604.1 - 0.19 11.7 0.2 26 4.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal topoisomerase domain DUF5305 PF17231.2 CCH61605.1 - 0.0044 16.5 0.6 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5305) Maf1 PF09174.10 CCH61606.1 - 4.7e-43 147.3 15.4 4.3e-36 124.7 11.1 2.6 1 1 1 2 2 2 2 Maf1 regulator Macoilin PF09726.9 CCH61606.1 - 0.27 9.8 15.2 0.34 9.4 15.2 1.1 1 0 0 1 1 1 0 Macoilin family CAC1F_C PF16885.5 CCH61606.1 - 1.4 8.5 8.7 2.1 7.9 8.7 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Sel1 PF08238.12 CCH61607.1 - 0.00011 22.7 3.0 0.03 15.0 0.1 3.4 3 0 0 3 3 3 2 Sel1 repeat Tcp11 PF05794.13 CCH61608.1 - 4e-132 441.4 3.4 6.8e-132 440.7 3.4 1.4 1 0 0 1 1 1 1 T-complex protein 11 PRESAN PF09687.10 CCH61608.1 - 0.065 13.8 2.6 0.5 10.9 0.1 3.1 3 0 0 3 3 3 0 Plasmodium RESA N-terminal Peptidase_A2B PF12384.8 CCH61609.1 - 1.3e-12 47.6 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase RVT_1 PF00078.27 CCH61609.1 - 1.2e-07 31.5 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.11 CCH61609.1 - 4.4e-07 29.7 0.1 9.7e-07 28.6 0.1 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 CCH61609.1 - 6.2e-06 26.7 0.0 9.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCH61609.1 - 1.7e-05 25.3 0.0 3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 CCH61610.1 - 3.1e-27 94.5 0.0 5.5e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH61610.1 - 1e-24 86.8 0.0 2e-24 85.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 CCH61611.1 - 1.1e-17 63.8 1.3 2.1e-17 63.0 0.8 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 CCH61611.1 - 1.4e-10 41.4 0.0 2.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain PIR PF00399.19 CCH61612.1 - 1.5e-49 164.5 80.0 4.3e-09 35.7 3.1 6.9 6 0 0 6 6 6 6 Yeast PIR protein repeat DUF4942 PF13708.6 CCH61612.1 - 0.052 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Aldo_ket_red PF00248.21 CCH61613.1 - 1.2e-38 133.0 0.0 1.3e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family REC114-like PF15165.6 CCH61613.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like AAA PF00004.29 CCH61614.1 - 3.7e-41 140.6 0.0 6.6e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH61614.1 - 1.9e-11 43.6 0.3 3.4e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCH61614.1 - 9.9e-09 35.0 0.1 2e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCH61614.1 - 9.9e-06 25.8 0.0 2.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CCH61614.1 - 1.1e-05 24.8 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CCH61614.1 - 1.7e-05 25.1 0.3 0.015 15.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 CCH61614.1 - 2e-05 24.6 0.0 9.1e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCH61614.1 - 0.00043 20.7 0.1 0.0023 18.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CCH61614.1 - 0.00063 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCH61614.1 - 0.0037 17.5 0.0 0.0083 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH61614.1 - 0.0083 16.7 0.1 0.034 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCH61614.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CCH61614.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 CCH61614.1 - 0.016 14.4 0.0 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_14 PF13173.6 CCH61614.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCH61614.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 CCH61614.1 - 0.04 13.1 0.1 0.6 9.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CCH61614.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CCH61614.1 - 0.045 13.1 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 CCH61614.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CCH61614.1 - 0.062 12.9 1.0 0.46 10.0 0.4 2.4 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCH61614.1 - 0.089 12.7 0.1 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 CCH61614.1 - 0.097 12.1 0.2 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 CCH61614.1 - 0.097 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 CCH61614.1 - 0.099 12.5 0.2 0.58 10.1 0.1 2.2 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.27 CCH61614.1 - 0.12 12.9 0.5 0.94 10.0 0.5 2.3 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CCH61614.1 - 0.15 11.8 1.2 0.3 10.8 0.3 2.1 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CCH61614.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C PF00481.21 CCH61615.1 - 1.8e-75 253.9 0.4 3.5e-75 253.0 0.4 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C EMP24_GP25L PF01105.24 CCH61616.1 - 4.7e-26 91.8 0.5 5.4e-26 91.6 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Njmu-R1 PF15053.6 CCH61616.1 - 0.00076 18.7 0.2 0.00094 18.4 0.2 1.1 1 0 0 1 1 1 1 Mjmu-R1-like protein family HTH_50 PF18024.1 CCH61616.1 - 0.046 13.3 0.5 0.075 12.7 0.5 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Rad50_zn_hook PF04423.14 CCH61616.1 - 0.14 12.0 1.5 0.23 11.3 1.5 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif CHD5 PF04420.14 CCH61616.1 - 0.2 11.5 1.1 0.35 10.7 1.1 1.5 1 1 0 1 1 1 0 CHD5-like protein zf-C3HC4_2 PF13923.6 CCH61617.1 - 0.0011 18.8 0.2 0.0024 17.6 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH61617.1 - 0.0018 18.2 0.3 0.0018 18.2 0.3 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCH61617.1 - 0.0019 18.0 0.2 0.0056 16.5 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH61617.1 - 0.0044 17.0 0.1 0.012 15.6 0.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCH61617.1 - 0.049 13.8 0.4 0.049 13.8 0.4 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CCH61617.1 - 0.059 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CCH61617.1 - 0.081 13.3 0.3 0.081 13.3 0.3 1.9 2 0 0 2 2 1 0 Ring finger domain Dynamin_N PF00350.23 CCH61617.1 - 0.12 12.4 3.5 3.5 7.7 0.6 2.7 3 0 0 3 3 3 0 Dynamin family Fer2_3 PF13085.6 CCH61617.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain IBR PF01485.21 CCH61617.1 - 0.21 11.8 0.9 2.8 8.2 0.1 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Vps36-NZF-N PF16988.5 CCH61617.1 - 0.6 9.6 2.3 0.61 9.5 0.1 2.2 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Com_YlbF PF06133.11 CCH61617.1 - 1.9 9.1 10.3 0.87 10.2 2.3 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA CYSTM PF12734.7 CCH61618.1 - 1.7 9.0 30.0 26 5.2 18.8 3.6 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance Mannosyl_trans3 PF11051.8 CCH61619.1 - 9.9e-86 287.5 0.0 1.8e-85 286.6 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative DUF2977 PF11192.8 CCH61619.1 - 0.028 14.5 0.3 4.7 7.4 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Secretin_N_2 PF07655.13 CCH61619.1 - 0.4 11.2 10.7 0.85 10.2 10.7 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Glutaredoxin PF00462.24 CCH61620.1 - 1.1e-11 44.8 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Pyrophosphatase PF00719.19 CCH61621.1 - 8.7e-59 197.9 0.3 1.4e-58 197.3 0.3 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Histone PF00125.24 CCH61622.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCH61622.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCH61622.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCH61622.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCH61622.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCH61622.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CCH61623.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCH61623.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CCH61623.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCH61623.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCH61623.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCH61623.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCH61623.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCH61623.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A NAD_Gly3P_dh_N PF01210.23 CCH61624.1 - 3.9e-50 169.9 0.1 8.2e-50 168.8 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CCH61624.1 - 9.8e-41 139.4 0.1 1.6e-40 138.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CCH61624.1 - 0.00061 20.3 0.0 2.3 8.9 0.0 3.3 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 CCH61624.1 - 0.12 12.9 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF21 PF01595.20 CCH61625.1 - 5.7e-30 104.3 0.2 9.5e-30 103.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CCH61625.1 - 0.00024 21.5 0.0 0.061 13.8 0.0 2.9 3 0 0 3 3 3 2 CBS domain Pkinase PF00069.25 CCH61626.1 - 1.8e-49 168.5 0.0 3.2e-49 167.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61626.1 - 3.3e-20 72.5 0.0 6.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CCH61626.1 - 0.012 15.3 0.3 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CCH61626.1 - 0.013 14.9 0.0 0.059 12.7 0.0 2.0 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 CCH61626.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pribosyl_synth PF14572.6 CCH61627.1 - 1.2e-43 149.2 0.4 2.1e-43 148.5 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CCH61627.1 - 5.6e-39 132.7 0.1 3.7e-38 130.0 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CCH61627.1 - 1.6e-12 47.2 1.2 9.6e-12 44.7 1.2 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCH61627.1 - 0.0099 15.3 0.2 0.018 14.5 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Adap_comp_sub PF00928.21 CCH61628.1 - 1.6e-76 257.2 0.2 2.1e-76 256.8 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family CRT10 PF08728.10 CCH61629.1 - 7.2e-135 450.9 0.7 1.1e-134 450.3 0.7 1.3 1 0 0 1 1 1 1 CRT10 Pkinase PF00069.25 CCH61630.1 - 1.5e-50 172.0 0.3 7.1e-50 169.8 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61630.1 - 2.8e-24 85.8 0.0 6.1e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2407 PF10302.9 CCH61630.1 - 1.5 9.4 7.3 5.9 7.5 5.0 3.3 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Actin PF00022.19 CCH61631.1 - 2.9e-110 368.7 0.0 8.9e-110 367.1 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCH61631.1 - 0.041 12.7 0.0 0.34 9.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein tRNA_Me_trans PF03054.16 CCH61632.1 - 7.3e-111 370.4 0.0 8.6e-111 370.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 CCH61632.1 - 8.6e-07 28.3 0.0 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 CCH61632.1 - 0.065 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Exo_endo_phos PF03372.23 CCH61633.1 - 0.017 14.6 0.0 0.055 13.0 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Transglut_core2 PF13369.6 CCH61633.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily NARP1 PF12569.8 CCH61634.1 - 2.3e-111 373.3 24.3 3.1e-81 273.8 1.7 3.4 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CCH61634.1 - 4.3e-16 57.7 5.9 0.0009 19.2 0.0 8.0 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH61634.1 - 1.3e-09 37.5 14.4 0.00027 20.9 0.0 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH61634.1 - 1.1e-08 35.4 0.5 0.065 13.7 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH61634.1 - 2.4e-08 34.1 0.0 0.23 12.4 0.0 6.4 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCH61634.1 - 4.7e-08 32.5 7.9 0.018 14.9 0.0 6.5 8 0 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH61634.1 - 3.1e-07 30.5 13.1 0.0044 17.2 0.0 5.2 6 0 0 6 6 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CCH61634.1 - 4.3e-07 30.5 0.0 0.95 10.2 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH61634.1 - 5.2e-07 29.6 2.1 0.14 12.6 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH61634.1 - 1.3e-05 25.4 0.2 6.7 7.1 0.0 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat YcaO_C PF18381.1 CCH61634.1 - 0.00057 19.8 0.1 0.0032 17.4 0.1 2.4 2 0 0 2 2 1 1 YcaO cyclodehydratase C-terminal domain TPR_11 PF13414.6 CCH61634.1 - 0.0022 17.6 3.9 0.012 15.3 0.0 3.9 5 0 0 5 5 4 1 TPR repeat TPR_7 PF13176.6 CCH61634.1 - 0.0072 16.3 5.0 7.7 6.8 0.0 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 CCH61634.1 - 0.011 15.8 0.3 8.6 6.5 0.0 3.3 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.6 CCH61634.1 - 0.013 15.6 9.7 1 9.5 0.1 4.7 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 CCH61634.1 - 0.019 14.5 2.3 0.13 11.7 0.1 3.1 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 CCH61634.1 - 0.029 15.0 4.1 0.67 10.7 0.0 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF3632 PF12311.8 CCH61634.1 - 0.084 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Trimer_CC PF08954.11 CCH61634.1 - 0.64 9.6 2.6 2 8.0 0.1 2.3 2 0 0 2 2 2 0 Trimerisation motif HLH PF00010.26 CCH61635.1 - 7.5e-17 61.0 0.1 1.7e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIR2 PF02146.17 CCH61636.1 - 1.6e-63 213.8 0.0 6e-63 212.0 0.0 1.8 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.13 CCH61636.1 - 1e-40 139.0 0.0 1.8e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 CCH61636.1 - 0.0071 16.1 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain SF3A2 PF16835.5 CCH61637.1 - 3.5e-18 65.7 0.3 6.7e-18 64.8 0.3 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CCH61637.1 - 5.3e-06 26.6 1.4 1.1e-05 25.7 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CCH61637.1 - 0.037 14.4 0.3 0.075 13.4 0.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CHCH PF06747.13 CCH61639.1 - 0.00035 20.6 1.2 0.00049 20.2 1.2 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CCH61639.1 - 0.0051 16.8 2.7 0.0077 16.2 2.7 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, E1_DerP2_DerF2 PF02221.15 CCH61640.1 - 3.8e-23 82.4 0.0 4.2e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 ML domain NPCBM_assoc PF10633.9 CCH61640.1 - 0.17 12.1 0.0 0.46 10.8 0.0 1.6 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Alph_Pro_TM PF09608.10 CCH61640.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Metallophos PF00149.28 CCH61641.1 - 2.5e-38 132.6 0.1 3.3e-38 132.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCH61641.1 - 0.0032 17.9 0.6 0.0067 16.8 0.6 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CCH61641.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PCI PF01399.27 CCH61642.1 - 7.5e-13 48.9 0.3 7.5e-13 48.9 0.3 2.9 3 1 0 3 3 3 1 PCI domain Smg4_UPF3 PF03467.15 CCH61643.1 - 3.6e-24 85.7 17.0 3.6e-24 85.7 17.0 4.4 2 2 0 2 2 2 1 Smg-4/UPF3 family PRP38 PF03371.15 CCH61644.1 - 2.4e-44 151.3 2.0 3e-44 151.0 2.0 1.0 1 0 0 1 1 1 1 PRP38 family DER1 PF04511.15 CCH61646.1 - 0.0044 17.0 7.7 0.0062 16.5 7.7 1.3 1 0 0 1 1 1 1 Der1-like family ABC_tran PF00005.27 CCH61647.1 - 1.5e-52 177.7 0.0 1.3e-25 90.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 CCH61647.1 - 1.5e-38 132.4 40.2 1.4e-26 93.3 13.2 2.6 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.6 CCH61647.1 - 2.1e-12 47.5 8.9 0.00034 20.5 0.1 4.7 4 1 1 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CCH61647.1 - 4.1e-09 36.6 5.6 0.00016 21.7 0.1 3.2 2 1 1 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CCH61647.1 - 2.1e-06 28.2 0.0 0.079 13.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 CCH61647.1 - 2.9e-06 26.9 3.3 0.0028 17.1 0.1 4.0 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCH61647.1 - 2.3e-05 24.5 0.4 0.048 13.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CCH61647.1 - 2.3e-05 24.7 0.5 1.2 9.4 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CCH61647.1 - 5.4e-05 22.9 8.1 0.049 13.4 0.1 3.2 4 0 0 4 4 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CCH61647.1 - 5.8e-05 23.4 0.1 0.059 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCH61647.1 - 7.3e-05 23.3 0.0 0.68 10.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CCH61647.1 - 0.00021 20.9 0.0 0.033 13.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 CCH61647.1 - 0.00024 21.7 8.2 0.18 12.3 0.0 3.4 2 1 1 3 3 2 2 AAA domain T2SSE PF00437.20 CCH61647.1 - 0.00032 19.9 0.1 0.066 12.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 CCH61647.1 - 0.00033 20.6 0.1 0.041 13.8 0.1 2.5 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 CCH61647.1 - 0.00045 20.2 0.0 0.86 9.5 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_30 PF13604.6 CCH61647.1 - 0.00065 19.5 0.1 0.55 9.9 0.2 2.3 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 CCH61647.1 - 0.0013 18.0 0.5 7.1 5.8 0.0 3.3 3 0 0 3 3 3 0 KAP family P-loop domain AAA_24 PF13479.6 CCH61647.1 - 0.0014 18.4 0.5 1.5 8.5 0.0 2.6 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CCH61647.1 - 0.0035 17.7 0.4 1.8 9.0 0.1 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 CCH61647.1 - 0.0043 17.0 0.1 3.8 7.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 CCH61647.1 - 0.0054 16.1 0.3 0.8 9.0 0.1 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.12 CCH61647.1 - 0.0078 15.7 1.3 0.094 12.2 0.2 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein Cytidylate_kin PF02224.18 CCH61647.1 - 0.023 14.4 0.8 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase Adeno_IVa2 PF02456.15 CCH61647.1 - 0.034 12.9 0.6 0.076 11.8 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 CCH61647.1 - 0.04 13.9 0.2 3 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 CCH61647.1 - 0.044 13.9 3.2 1.8 8.6 0.5 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 CCH61647.1 - 0.069 12.3 0.1 0.87 8.7 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 CCH61647.1 - 0.07 13.5 0.3 0.67 10.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CCH61647.1 - 0.079 13.4 0.0 25 5.3 0.0 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CCH61647.1 - 0.081 13.4 0.1 3.1 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CCH61647.1 - 0.084 12.9 0.0 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CCH61647.1 - 0.084 12.7 0.1 12 5.6 0.1 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 CCH61647.1 - 0.089 12.4 3.2 2.7 7.5 0.9 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 CCH61647.1 - 0.096 12.9 0.3 38 4.6 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 CCH61647.1 - 0.12 12.5 0.1 10 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CCH61647.1 - 0.16 11.7 0.6 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LapA_dom PF06305.11 CCH61647.1 - 0.27 11.1 1.1 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Zeta_toxin PF06414.12 CCH61647.1 - 0.33 10.2 0.8 6.5 6.0 0.4 2.2 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 CCH61647.1 - 0.42 10.5 1.4 1.9 8.4 0.3 2.4 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 CCH61647.1 - 0.61 9.8 2.2 22 4.7 0.6 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC2_membrane_3 PF12698.7 CCH61647.1 - 0.71 8.9 37.7 0.1 11.7 17.8 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein SRPRB PF09439.10 CCH61647.1 - 5.1 6.5 7.4 21 4.5 0.0 3.5 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit Haem_degrading PF03928.14 CCH61648.1 - 5.4e-28 97.4 0.0 7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading NatB_MDM20 PF09797.9 CCH61649.1 - 1.7e-42 145.7 10.7 1.7e-42 145.7 10.7 3.3 3 1 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit Brix PF04427.18 CCH61650.1 - 2.4e-40 138.7 0.2 3.8e-40 138.1 0.2 1.3 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 CCH61650.1 - 0.098 11.2 0.2 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin CRIM PF16978.5 CCH61651.1 - 5.5e-38 130.3 9.2 4.5e-36 124.1 1.3 3.3 3 0 0 3 3 3 2 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CCH61651.1 - 4e-29 101.1 1.7 4e-29 101.1 1.7 3.0 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PH PF00169.29 CCH61651.1 - 0.0043 17.5 2.7 0.0099 16.4 0.3 3.1 3 0 0 3 3 3 1 PH domain RNase_T PF00929.24 CCH61652.1 - 1.1e-17 65.1 0.2 2.6e-17 63.8 0.0 1.7 2 1 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CCH61652.1 - 0.00052 19.8 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Str_synth PF03088.16 CCH61652.1 - 0.055 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Strictosidine synthase RasGAP PF00616.19 CCH61653.1 - 7.8e-25 87.8 0.7 1e-16 61.3 0.3 3.8 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase ParcG PF10274.9 CCH61653.1 - 0.0092 16.1 1.4 0.2 11.7 0.6 3.1 2 0 0 2 2 2 1 Parkin co-regulated protein eRF1_2 PF03464.15 CCH61654.1 - 9.9e-47 158.6 0.2 2.1e-46 157.5 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCH61654.1 - 3.1e-39 134.0 0.3 6.3e-39 133.0 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCH61654.1 - 4e-19 68.9 0.0 7.3e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CCH61654.1 - 1.9e-10 41.1 0.1 2.9e-10 40.5 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CCH61654.1 - 4.6e-09 36.6 0.1 7.3e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Tnp_DNA_bind PF14706.6 CCH61654.1 - 0.0092 15.8 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 Transposase DNA-binding DUF4825 PF16107.5 CCH61654.1 - 0.048 13.8 1.0 5.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4825) ATG19_autophagy PF12744.7 CCH61655.1 - 6e-09 35.5 3.9 6e-09 35.5 3.9 3.2 2 1 0 3 3 3 2 Autophagy protein Atg19, Atg8-binding ZZ PF00569.17 CCH61655.1 - 8.3e-08 31.9 5.3 1.9e-07 30.8 5.3 1.6 1 1 0 1 1 1 1 Zinc finger, ZZ type 7TMR-HDED PF07697.11 CCH61655.1 - 0.036 14.2 0.9 0.036 14.2 0.9 2.8 3 0 0 3 3 3 0 7TM-HD extracellular DUF3795 PF12675.7 CCH61655.1 - 1.2 9.6 4.9 0.22 12.0 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) Ribosomal_S9 PF00380.19 CCH61656.1 - 7.7e-42 142.6 0.5 2.2e-41 141.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 CENP-S PF15630.6 CCH61657.1 - 8.7e-24 83.7 0.0 1e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CCH61657.1 - 4e-08 33.3 0.0 4.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 CCH61657.1 - 0.018 15.1 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3337 PF11816.8 CCH61658.1 - 3.3e-15 56.4 2.0 7.4e-13 48.7 0.3 3.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 CCH61658.1 - 0.0055 17.5 7.4 1.7 9.6 0.3 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat RAWUL PF16207.5 CCH61658.1 - 0.0059 17.2 1.5 0.033 14.9 0.2 2.7 2 0 0 2 2 2 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like RNA_pol_Rpb5_C PF01191.19 CCH61659.1 - 2.1e-33 114.0 0.4 4.2e-33 113.0 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CCH61659.1 - 1.2e-28 99.5 0.1 2.2e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 CCH61659.1 - 0.0095 16.2 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 Sof1-like domain Mrr_cat PF04471.12 CCH61659.1 - 0.035 14.1 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease PTase_Orf2 PF11468.8 CCH61659.1 - 0.039 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 RibD_C PF01872.17 CCH61660.1 - 1.7e-31 109.7 0.0 1.9e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain TRAP_alpha PF03896.16 CCH61661.1 - 1.2 8.2 8.3 0.061 12.5 2.6 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SUZ PF12752.7 CCH61661.1 - 3.2 8.6 6.5 25 5.7 0.6 2.7 2 0 0 2 2 2 0 SUZ domain MFAP1 PF06991.11 CCH61661.1 - 8.1 6.2 22.4 1.9e+02 1.8 22.3 2.4 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Sbi-IV PF11621.8 CCH61661.1 - 8.4 6.8 10.0 6 7.3 0.9 2.9 2 1 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Suc_Fer-like PF06999.12 CCH61662.1 - 9.5e-47 159.4 0.0 1.3e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF3530 PF12048.8 CCH61662.1 - 0.028 13.9 0.3 0.039 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF899 PF05988.12 CCH61662.1 - 0.063 12.8 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Fungal_trans PF04082.18 CCH61663.1 - 3.2e-21 75.6 12.2 3.2e-21 75.6 12.2 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH61663.1 - 7.5e-07 29.2 12.4 1.5e-06 28.2 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 CCH61664.1 - 7.2e-15 55.2 0.0 1.8e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain EnY2 PF10163.9 CCH61665.1 - 7.3e-22 77.6 5.0 8.4e-22 77.4 5.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Rep_fac_C PF08542.11 CCH61665.1 - 0.042 14.3 1.8 0.19 12.2 1.8 1.9 1 1 0 1 1 1 0 Replication factor C C-terminal domain COMPASS-Shg1 PF05205.12 CCH61665.1 - 1.1 9.9 8.5 3.4 8.4 0.9 2.1 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 TPR_1 PF00515.28 CCH61666.1 - 1.2e-43 145.2 21.2 3e-07 30.0 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CCH61666.1 - 1.9e-39 130.6 24.3 0.00016 21.5 0.0 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 CCH61666.1 - 8.2e-27 91.6 22.2 0.00011 22.3 0.0 11.6 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 CCH61666.1 - 2.5e-22 77.2 18.2 0.09 13.0 0.0 10.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.6 CCH61666.1 - 1.5e-19 69.4 16.1 0.0015 18.1 0.0 8.0 3 2 5 8 8 8 5 TPR repeat TPR_16 PF13432.6 CCH61666.1 - 2.4e-18 66.5 17.2 6e-05 23.6 0.8 6.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CCH61666.1 - 2.4e-18 65.2 22.0 0.02 15.7 0.2 9.7 4 2 6 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 CCH61666.1 - 3e-14 53.0 31.4 0.0005 20.3 0.3 8.0 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCH61666.1 - 9.1e-13 48.5 20.6 0.0028 18.1 0.4 7.9 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCH61666.1 - 9.2e-13 47.3 20.7 0.066 13.3 0.2 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCH61666.1 - 1.1e-11 44.7 15.6 0.072 13.3 1.6 6.5 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 CCH61666.1 - 3.4e-11 43.0 14.9 0.8 10.5 0.0 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCH61666.1 - 0.12 12.3 11.4 9.8 6.2 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.16 CCH61667.1 - 5.9e-76 255.1 0.0 7.6e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CCH61667.1 - 5.6e-17 61.8 0.0 8.1e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.27 CCH61668.1 - 1.4e-07 31.0 13.1 3.7e-07 29.6 10.1 2.6 2 0 0 2 2 2 1 GATA zinc finger Serglycin PF04360.12 CCH61669.1 - 2.9e-05 24.1 0.3 4.2e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 Serglycin AF-4 PF05110.13 CCH61669.1 - 0.0052 15.0 1.5 0.0065 14.6 1.5 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein HSM3_C PF18794.1 CCH61670.1 - 4.4e-50 169.7 2.9 9.6e-50 168.6 2.9 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, C terminal domain HSM3_N PF18795.1 CCH61670.1 - 4.9e-29 101.4 12.3 8.5e-29 100.7 12.3 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain DASH_Duo1 PF08651.10 CCH61670.1 - 0.12 12.2 4.3 0.45 10.3 4.3 2.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 NPV_P10 PF05531.12 CCH61670.1 - 1.1 9.8 6.5 0.45 11.0 3.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein rRNA_proc-arch PF13234.6 CCH61671.1 - 9.6e-82 274.9 1.7 9.6e-82 274.9 1.7 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CCH61671.1 - 3.7e-52 176.3 0.9 9e-52 175.0 0.9 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CCH61671.1 - 3e-19 69.4 0.1 1.9e-17 63.6 0.0 3.1 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61671.1 - 2e-06 28.1 0.0 2.2e-05 24.8 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH61671.1 - 0.0014 18.6 0.0 0.0063 16.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCH61671.1 - 0.044 14.1 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCH61671.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein PDR_assoc PF08370.11 CCH61672.1 - 0.11 12.2 0.8 0.46 10.3 0.8 2.0 1 0 0 1 1 1 0 Plant PDR ABC transporter associated zf-C2H2 PF00096.26 CCH61673.1 - 3.2e-23 80.8 52.4 1.2e-05 25.5 0.5 8.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH61673.1 - 1.3e-18 66.5 45.4 4.5e-08 33.2 0.7 7.0 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH61673.1 - 3.1e-14 52.5 65.9 0.00053 20.6 0.5 9.2 9 0 0 9 9 8 6 C2H2-type zinc finger Zap1_zf2 PF18217.1 CCH61673.1 - 3.1e-11 43.0 9.9 3.1e-11 43.0 9.9 6.4 6 0 0 6 6 6 1 Zap1 zinc finger 2 zf-met PF12874.7 CCH61673.1 - 3.9e-05 23.9 25.4 0.049 14.0 2.7 5.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCH61673.1 - 0.008 16.4 36.3 0.14 12.5 1.9 6.7 7 0 0 7 7 5 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CCH61673.1 - 0.014 16.0 6.7 0.046 14.4 1.4 6.9 7 2 2 9 9 5 0 FOXP coiled-coil domain zf_Hakai PF18408.1 CCH61673.1 - 0.024 14.3 0.1 0.1 12.3 0.1 2.2 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-C2HC_2 PF13913.6 CCH61673.1 - 0.15 12.0 0.1 0.15 12.0 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CCH61673.1 - 0.16 11.7 13.7 0.65 9.8 0.2 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type zf_ZIC PF18366.1 CCH61673.1 - 0.24 11.5 0.1 0.24 11.5 0.1 5.9 6 1 1 7 7 7 0 Zic proteins zinc finger domain Zn-ribbon_8 PF09723.10 CCH61673.1 - 6.5 7.0 12.8 0.51 10.5 1.5 3.7 2 2 2 4 4 4 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 CCH61673.1 - 9.9 6.3 35.4 1 9.4 1.6 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger Nup88 PF10168.9 CCH61674.1 - 2e-06 26.0 18.2 1.7e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 Nuclear pore component Ribosomal_L37 PF08561.10 CCH61675.1 - 6.5e-21 75.1 11.0 1.2e-16 61.3 0.4 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.22 CCH61676.1 - 8.3e-14 51.9 1.3 6.8e-09 35.8 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCH61676.1 - 8.2e-05 22.1 0.4 0.00015 21.2 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily zf-C2H2_2 PF12756.7 CCH61677.1 - 4.4e-34 116.8 6.2 4.5e-32 110.4 3.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) NOA36 PF06524.12 CCH61677.1 - 0.36 10.1 9.3 0.21 10.9 1.6 2.2 2 0 0 2 2 2 0 NOA36 protein Presenilin PF01080.17 CCH61677.1 - 0.44 9.3 1.8 0.66 8.7 1.8 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_L17 PF01196.19 CCH61679.1 - 1.5e-17 64.3 1.1 5.8e-17 62.4 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein L17 Mrpl_C PF18502.1 CCH61679.1 - 0.00095 19.4 2.2 0.00095 19.4 2.2 2.6 2 1 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain DSPc PF00782.20 CCH61680.1 - 1.6e-31 108.9 5.2 2e-23 82.7 0.3 3.7 4 0 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCH61680.1 - 0.00023 20.8 0.0 0.024 14.2 0.0 2.6 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CCH61680.1 - 0.0044 17.3 0.3 0.53 10.6 0.0 2.9 3 0 0 3 3 3 1 Rit1 DUSP-like domain CDKN3 PF05706.12 CCH61680.1 - 0.027 14.1 0.1 0.027 14.1 0.1 2.7 3 1 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) CBFD_NFYB_HMF PF00808.23 CCH61681.1 - 6.9e-06 26.3 0.4 1.3e-05 25.4 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndufs5 PF10200.9 CCH61681.1 - 0.008 16.4 0.1 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa BslA PF17735.1 CCH61681.1 - 0.069 13.1 1.0 0.18 11.8 0.2 1.9 1 1 1 2 2 2 0 Biofilm surface layer A Aa_trans PF01490.18 CCH61682.1 - 3.2e-92 309.4 27.0 3.7e-92 309.2 27.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2970 PF11174.8 CCH61682.1 - 0.48 10.3 0.0 0.48 10.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) Aa_trans PF01490.18 CCH61683.1 - 1.3e-93 314.0 22.5 1.4e-93 313.8 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein JAKMIP_CC3 PF16034.5 CCH61683.1 - 0.25 11.2 0.2 0.37 10.7 0.2 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain SLATT_4 PF18186.1 CCH61683.1 - 7.7 6.1 6.0 0.56 9.8 0.2 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Ribosomal_S21 PF01165.20 CCH61684.1 - 5.8e-09 35.5 0.1 9.8e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Urm1 PF09138.11 CCH61685.1 - 1.1e-32 112.3 0.1 1.2e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) Motile_Sperm PF00635.26 CCH61686.1 - 7.3e-26 90.2 1.1 1e-25 89.6 0.1 1.9 2 0 0 2 2 2 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CCH61686.1 - 0.0042 17.3 0.7 0.01 16.1 0.1 1.9 2 0 0 2 2 2 1 Transmembrane protein 131-like TFIIA PF03153.13 CCH61686.1 - 0.017 15.1 30.2 0.026 14.6 30.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PapD-like PF14874.6 CCH61686.1 - 0.026 14.7 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like MRP-S27 PF10037.9 CCH61686.1 - 0.064 12.1 6.8 0.09 11.6 6.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 UPF0669 PF17065.5 CCH61686.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.0 1 1 1 2 2 2 0 Putative cytokine, C6ORF120 MetallophosN PF16371.5 CCH61686.1 - 0.24 11.7 2.7 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Presenilin PF01080.17 CCH61686.1 - 0.42 9.3 7.7 0.59 8.8 7.7 1.3 1 0 0 1 1 1 0 Presenilin DUF4813 PF16072.5 CCH61686.1 - 1.8 8.2 28.5 3.4 7.3 28.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF4834 PF16118.5 CCH61686.1 - 4.1 8.4 9.5 9.2 7.3 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 CCH61686.1 - 5.1 7.5 6.9 4.6e+02 1.2 6.8 2.6 1 1 0 1 1 1 0 Orf78 (ac78) CCDC53 PF10152.9 CCH61686.1 - 9.4 6.6 20.7 3.3 8.1 15.3 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex ArfGap PF01412.18 CCH61687.1 - 7.9e-31 106.6 0.2 7.9e-31 106.6 0.2 3.0 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf 4HBT PF03061.22 CCH61688.1 - 1.8e-07 31.4 0.0 4e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily Cnd2 PF05786.14 CCH61689.1 - 7.3e-129 431.7 60.4 5.9e-127 425.4 60.4 2.2 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CCH61689.1 - 0.00063 19.9 0.1 0.00063 19.9 0.1 4.0 5 0 0 5 5 5 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Peptidase_M41 PF01434.18 CCH61690.1 - 1.9e-57 194.2 0.0 3.6e-57 193.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CCH61690.1 - 6e-41 140.0 0.0 1.5e-40 138.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH61690.1 - 4e-08 32.9 0.0 1.2e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CCH61690.1 - 1.3e-05 25.7 0.4 8.9e-05 22.9 0.4 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH61690.1 - 4.1e-05 23.9 0.2 0.13 12.5 0.0 3.3 4 0 0 4 4 3 2 AAA domain RuvB_N PF05496.12 CCH61690.1 - 0.0003 20.6 0.0 0.0041 16.9 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CCH61690.1 - 0.00036 19.9 0.0 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 CCH61690.1 - 0.0025 17.8 0.1 0.011 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CCH61690.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CCH61690.1 - 0.025 15.2 0.3 0.42 11.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CCH61690.1 - 0.03 13.9 1.1 1.5 8.4 0.4 2.5 1 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CCH61690.1 - 0.033 13.5 0.0 0.57 9.5 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 CCH61690.1 - 0.057 13.6 0.0 0.24 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CCH61690.1 - 0.058 12.8 0.2 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CCH61690.1 - 0.07 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CCH61690.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CCH61690.1 - 0.093 12.8 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCH61690.1 - 0.18 11.5 0.1 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Cyclin_C_2 PF16899.5 CCH61691.1 - 1.7e-26 92.6 8.1 8.2e-26 90.4 6.4 2.7 2 1 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CCH61691.1 - 8.9e-10 38.4 0.5 2.4e-09 37.0 0.5 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain SIN1 PF05422.12 CCH61691.1 - 0.0041 17.7 7.3 0.0041 17.7 7.3 1.9 2 0 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) Menin PF05053.13 CCH61691.1 - 0.86 7.9 11.2 1.3 7.3 11.2 1.3 1 0 0 1 1 1 0 Menin Ndc1_Nup PF09531.10 CCH61691.1 - 1.2 7.7 10.8 2.2 6.9 10.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TB2_DP1_HVA22 PF03134.19 CCH61692.1 - 2.3e-23 81.9 3.2 3.9e-23 81.2 3.2 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2207 PF09972.9 CCH61692.1 - 0.58 8.9 3.2 1.3 7.7 3.3 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Arrestin_C PF02752.22 CCH61693.1 - 3.2e-11 43.8 5.5 1.3e-09 38.6 2.6 3.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain HLH PF00010.26 CCH61694.1 - 5.2e-13 48.7 0.4 5.2e-13 48.7 0.4 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain zf-HC5HC2H_2 PF13832.6 CCH61695.1 - 5.3e-31 107.0 5.8 5.3e-31 107.0 5.8 2.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CCH61695.1 - 3.7e-27 94.4 3.5 3.7e-27 94.4 3.5 3.6 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CCH61695.1 - 8.8e-14 50.8 2.5 8.8e-14 50.8 2.5 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CCH61695.1 - 1.2e-10 41.1 4.7 1.2e-10 41.1 4.7 3.0 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 CCH61695.1 - 6.5e-07 29.9 2.8 6.5e-07 29.9 2.8 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.22 CCH61695.1 - 0.0075 16.1 0.3 0.0075 16.1 0.3 3.2 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CCH61695.1 - 0.0084 16.0 3.4 0.0084 16.0 3.4 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 CCH61695.1 - 0.62 10.4 21.0 0.28 11.5 8.3 3.1 2 0 0 2 2 2 0 RING-like domain HLH PF00010.26 CCH61696.1 - 1.7e-19 69.5 0.8 3.6e-19 68.4 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 CCH61697.1 - 1.6e-50 171.9 0.5 4.1e-49 167.3 0.5 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61697.1 - 4.3e-27 95.0 0.0 1.3e-26 93.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCH61697.1 - 6.4e-15 55.3 0.0 2.3e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 CCH61697.1 - 0.00043 19.2 0.0 0.00072 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 CCH61697.1 - 0.001 19.3 0.0 0.0071 16.6 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 CCH61697.1 - 0.034 13.5 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3589 PF12141.8 CCH61698.1 - 1.4e-73 248.2 10.8 8.3e-48 163.2 0.1 2.8 1 1 1 2 2 2 2 Beta-mannosyltransferases TFB6 PF17110.5 CCH61699.1 - 2.6e-36 125.0 0.0 9.2e-33 113.4 0.0 2.5 2 1 1 3 3 3 2 Subunit 11 of the general transcription factor TFIIH SOG2 PF10428.9 CCH61700.1 - 6.8e-123 411.5 43.7 6.8e-123 411.5 43.7 3.5 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.7 CCH61700.1 - 1.4e-13 50.7 17.0 1.3e-08 35.0 1.2 6.3 4 3 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCH61700.1 - 4.6e-11 42.3 21.0 2.5e-08 33.5 3.4 4.6 4 1 1 5 5 5 3 Leucine rich repeat SpecificRecomb PF10136.9 CCH61700.1 - 0.0078 14.6 2.2 0.015 13.6 2.2 1.4 1 0 0 1 1 1 1 Site-specific recombinase Cyto_heme_lyase PF01265.17 CCH61701.1 - 1.4e-95 320.2 1.5 2.9e-95 319.2 1.5 1.4 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Sugar_tr PF00083.24 CCH61702.1 - 1.6e-160 534.9 36.6 1.9e-160 534.7 36.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH61702.1 - 3.9e-35 121.4 31.7 8.5e-35 120.3 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COPIIcoated_ERV PF07970.12 CCH61703.1 - 2.4e-72 243.4 0.1 2.9e-72 243.1 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCH61703.1 - 1.6e-27 95.7 0.1 4e-27 94.4 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) YmaF PF12788.7 CCH61703.1 - 0.095 13.3 0.1 0.28 11.7 0.1 1.8 1 0 0 1 1 1 0 YmaF family ETF_QO PF05187.13 CCH61704.1 - 6.9e-44 148.2 0.7 1.3e-43 147.4 0.7 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CCH61704.1 - 4.5e-08 33.1 0.0 1.8e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH61704.1 - 8.7e-07 29.1 0.0 6e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCH61704.1 - 2.3e-06 27.0 0.0 0.0096 15.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CCH61704.1 - 8.6e-06 25.2 0.0 0.005 16.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 CCH61704.1 - 8.5e-05 21.9 0.0 0.00073 18.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CCH61704.1 - 0.00011 21.6 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCH61704.1 - 0.00082 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Fer4_7 PF12838.7 CCH61704.1 - 0.0013 19.3 1.0 0.0031 18.1 1.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_oxidored PF12831.7 CCH61704.1 - 0.0033 16.8 0.0 0.0053 16.2 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CCH61704.1 - 0.004 16.4 0.1 0.0067 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CCH61704.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CCH61704.1 - 0.0073 16.8 0.1 4.3 8.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CCH61704.1 - 0.054 12.3 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 CCH61704.1 - 0.13 11.2 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.6 CCH61704.1 - 0.19 10.8 0.0 1.1 8.4 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyclin_N PF00134.23 CCH61705.1 - 6.1e-21 74.5 0.5 1.3e-20 73.4 0.5 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain TRAM_LAG1_CLN8 PF03798.16 CCH61707.1 - 5.4e-35 120.9 13.0 5.4e-35 120.9 13.0 1.8 2 0 0 2 2 2 1 TLC domain CDP-OH_P_transf PF01066.21 CCH61708.1 - 6.5e-13 49.2 0.3 6.5e-13 49.2 0.3 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GWT1 PF06423.12 CCH61708.1 - 0.19 11.8 3.5 0.22 11.6 1.3 1.9 2 0 0 2 2 2 0 GWT1 RNase_PH PF01138.21 CCH61709.1 - 1.4e-20 74.1 0.0 2.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCH61709.1 - 2.8e-07 30.5 2.0 8.1e-07 29.0 0.7 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF3977 PF13122.6 CCH61709.1 - 0.078 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3977) tRNA-synt_1 PF00133.22 CCH61710.1 - 1.6e-234 779.7 4.4 1.7e-234 779.6 0.1 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCH61710.1 - 4.8e-30 104.5 2.8 4.8e-30 104.5 2.8 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCH61710.1 - 4.3e-14 52.1 0.3 2.9e-07 29.6 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCH61710.1 - 5e-08 32.7 0.1 9.7e-07 28.5 0.0 3.2 3 1 1 4 4 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CCH61710.1 - 0.00013 22.1 8.0 0.00013 22.1 8.0 3.1 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CCH61710.1 - 0.0017 17.7 1.9 0.52 9.6 0.0 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Lzipper-MIP1 PF14389.6 CCH61710.1 - 0.016 15.5 4.1 0.041 14.2 4.1 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 tRNA-synt_1b PF00579.25 CCH61710.1 - 0.13 11.5 5.3 1.1 8.5 0.0 3.3 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) tRNA-synt_1c PF00749.21 CCH61710.1 - 3.2 6.6 8.8 1.3 7.9 0.0 3.6 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain ABC_transp_aux PF09822.9 CCH61710.1 - 4.1 6.8 8.2 3.7 6.9 1.3 2.3 2 0 0 2 2 2 0 ABC-type uncharacterized transport system Alpha_Helical PF18489.1 CCH61710.1 - 8.2 6.6 6.9 2.9 8.1 2.4 2.5 2 0 0 2 2 2 0 Alpha helical domain CwfJ_C_1 PF04677.15 CCH61711.1 - 5.4e-27 94.1 0.6 5.4e-27 94.1 0.6 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CCH61711.1 - 2.8e-15 57.0 0.1 9.5e-15 55.3 0.1 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF4548 PF15081.6 CCH61711.1 - 0.032 14.1 0.2 3 7.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4548) RNA_pol_A_bac PF01000.26 CCH61712.1 - 2.6e-30 105.1 0.0 5.3e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCH61712.1 - 3.7e-21 74.3 0.0 5.2e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nrap_D5 PF17406.2 CCH61713.1 - 1.9e-51 174.0 0.0 5.5e-51 172.5 0.0 1.9 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CCH61713.1 - 4.5e-50 170.0 0.8 8.6e-50 169.1 0.8 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CCH61713.1 - 1.6e-48 164.4 2.4 3.7e-46 156.7 1.0 3.1 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 CCH61713.1 - 2.3e-43 147.9 4.8 2.3e-43 147.9 4.8 2.5 3 0 0 3 3 3 1 Nrap protein domain 1 Nrap_D3 PF17404.2 CCH61713.1 - 6e-39 133.7 0.0 1.7e-38 132.3 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 CCH61713.1 - 1.7e-28 99.5 0.4 1.7e-28 99.5 0.4 2.2 2 0 0 2 2 2 1 Nrap protein domain 6 DUF2052 PF09747.9 CCH61713.1 - 1.5 8.9 17.5 2.9 8.0 17.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.11 CCH61713.1 - 1.9 8.1 19.4 3.1 7.4 19.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Tim54 PF11711.8 CCH61713.1 - 2.5 6.8 8.5 4.1 6.1 8.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.14 CCH61713.1 - 3.6 7.3 16.0 8.9 6.0 16.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 CCH61713.1 - 5.3 5.2 14.7 8.1 4.6 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein GPCR_chapero_1 PF11904.8 CCH61713.1 - 6 6.2 10.5 11 5.3 10.5 1.4 1 0 0 1 1 1 0 GPCR-chaperone Presenilin PF01080.17 CCH61713.1 - 6.9 5.3 7.4 9.3 4.9 7.4 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CCH61713.1 - 7.2 6.8 9.4 14 5.9 9.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Aldo_ket_red PF00248.21 CCH61714.1 - 1.1e-41 143.0 0.0 1.5e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.25 CCH61715.1 - 1.1e-20 74.1 2.7 1.4e-20 73.8 2.4 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61715.1 - 3.9e-10 39.4 0.9 9.5e-10 38.2 0.9 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4934 PF16288.5 CCH61715.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) FTA2 PF13095.6 CCH61715.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pil1 PF13805.6 CCH61716.1 - 5.2e-118 393.3 0.1 7.4e-118 392.8 0.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 COG4 PF08318.12 CCH61717.1 - 4.1e-87 292.4 5.2 8.8e-87 291.3 5.2 1.6 1 0 0 1 1 1 1 COG4 transport protein Proteasome PF00227.26 CCH61718.1 - 1.2e-48 165.1 0.1 1.5e-48 164.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit L51_S25_CI-B8 PF05047.16 CCH61719.1 - 3.9e-08 33.1 0.0 6.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RPM2 PF08579.11 CCH61719.1 - 0.064 13.7 0.1 0.08 13.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4149 PF13664.6 CCH61720.1 - 5.3e-18 65.2 1.6 8.8e-18 64.5 1.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF3818 PF12825.7 CCH61721.1 - 6.9e-109 363.9 23.1 6.9e-109 363.9 23.1 3.3 3 0 0 3 3 3 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CCH61721.1 - 1.6e-34 118.7 1.9 6.4e-34 116.7 1.9 2.1 1 0 0 1 1 1 1 PX-associated PX PF00787.24 CCH61721.1 - 3.8e-09 36.5 3.6 6.8e-09 35.7 1.5 2.7 2 0 0 2 2 2 1 PX domain Response_reg PF00072.24 CCH61721.1 - 0.027 14.6 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 0 Response regulator receiver domain ELFV_dehydrog PF00208.21 CCH61722.1 - 2.7e-80 269.6 2.7 3.3e-80 269.3 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CCH61722.1 - 5.5e-48 162.1 0.0 9.8e-48 161.3 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Calreticulin PF00262.18 CCH61723.1 - 2.1e-125 418.4 14.0 2.9e-125 417.9 14.0 1.2 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.22 CCH61724.1 - 5.6e-177 588.9 0.4 6.4e-177 588.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CCH61724.1 - 0.064 12.7 0.1 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) MCM PF00493.23 CCH61726.1 - 1.5e-103 344.7 0.1 2.1e-103 344.2 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCH61726.1 - 1.5e-39 134.7 0.0 4.6e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 CCH61726.1 - 4.9e-29 100.7 0.1 1.5e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CCH61726.1 - 3.7e-25 88.2 0.3 1.3e-24 86.4 0.2 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CCH61726.1 - 1.1e-22 80.5 0.2 6e-22 78.2 0.1 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCH61726.1 - 4.2e-07 29.6 0.0 1.5e-06 27.7 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCH61726.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CCH61726.1 - 0.02 14.7 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pepsin-I3 PF06394.13 CCH61726.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Tir_receptor_M PF03549.14 CCH61726.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Phosphorylase PF00343.20 CCH61727.1 - 0 1029.2 0.0 0 1028.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Repressor_Mnt PF11423.8 CCH61727.1 - 0.16 11.8 0.2 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 Regulatory protein Mnt DUF5341 PF17276.2 CCH61728.1 - 1.5e-15 57.7 5.4 2.8e-15 56.9 5.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5341) SNARE PF05739.19 CCH61728.1 - 8.8 6.4 7.9 36 4.5 0.1 2.4 2 0 0 2 2 2 0 SNARE domain zf-CCHC PF00098.23 CCH61731.1 - 8.2e-10 38.3 37.2 0.0006 19.8 2.2 4.9 4 1 0 4 4 4 3 Zinc knuckle zf-C2H2_10 PF16588.5 CCH61731.1 - 0.0031 17.2 2.0 0.0031 17.2 2.0 4.4 3 1 1 4 4 4 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CCH61731.1 - 0.011 15.5 30.7 1.2 8.9 0.6 5.3 4 1 1 5 5 5 0 Zinc knuckle DUF1689 PF07954.11 CCH61732.1 - 5.6e-43 146.8 2.6 7.8e-43 146.4 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) MgtC PF02308.16 CCH61732.1 - 0.25 11.7 0.0 0.36 11.2 0.0 1.1 1 0 0 1 1 1 0 MgtC family Coatomer_E PF04733.14 CCH61733.1 - 3e-05 23.6 8.5 0.00021 20.8 8.5 2.1 1 1 0 1 1 1 1 Coatomer epsilon subunit NBD94 PF16830.5 CCH61733.1 - 0.017 15.5 1.6 0.017 15.5 1.6 3.4 3 1 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH DUF4248 PF14053.6 CCH61733.1 - 0.044 13.8 0.4 0.52 10.4 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) DHO_dh PF01180.21 CCH61734.1 - 6.7e-99 330.8 0.2 8.1e-99 330.6 0.2 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CCH61734.1 - 0.048 12.7 0.0 1.6 7.7 0.1 2.3 2 1 0 2 2 2 0 FMN-dependent dehydrogenase RPN2_C PF18004.1 CCH61735.1 - 9.1e-50 168.7 4.4 1.5e-49 168.0 4.4 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CCH61735.1 - 2e-38 128.9 23.5 6.6e-06 26.3 0.7 9.6 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCH61735.1 - 9.2e-19 67.6 0.9 5.4e-14 52.3 0.1 4.8 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 CCH61735.1 - 2.4e-09 36.7 1.2 1.6 9.2 0.0 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 CCH61735.1 - 5.1e-08 33.3 3.0 0.25 11.9 0.0 5.3 5 1 1 6 6 6 2 HEAT-like repeat Cnd1 PF12717.7 CCH61735.1 - 0.0042 17.2 5.4 12 6.0 0.0 4.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 CCH61735.1 - 0.024 14.9 0.9 0.19 12.0 0.0 3.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Vfa1 PF08432.10 CCH61735.1 - 0.063 13.6 12.3 0.3 11.4 9.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ERAP1_C PF11838.8 CCH61735.1 - 0.11 12.1 2.6 2.7 7.4 0.0 3.4 3 1 1 4 4 4 0 ERAP1-like C-terminal domain Arm PF00514.23 CCH61735.1 - 0.16 12.1 0.3 67 3.7 0.1 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Striatin PF08232.12 CCH61735.1 - 8.7 6.9 8.7 18 5.9 8.7 1.4 1 0 0 1 1 1 0 Striatin family 2-Hacid_dh_C PF02826.19 CCH61736.1 - 9e-51 171.8 0.0 1.6e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCH61736.1 - 1.6e-39 134.7 0.1 2.1e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCH61736.1 - 0.00022 21.4 0.4 0.0029 17.8 0.1 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 CCH61736.1 - 0.0034 17.9 0.1 0.016 15.7 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 CCH61736.1 - 0.025 14.7 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain APH PF01636.23 CCH61737.1 - 1.1e-12 48.5 0.0 1.5e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_M24 PF00557.24 CCH61738.1 - 4.8e-46 157.1 0.0 7.2e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCH61738.1 - 5.9e-39 132.6 0.0 1.6e-38 131.2 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain CAF1C_H4-bd PF12265.8 CCH61738.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex RTP PF02334.16 CCH61738.1 - 0.16 12.6 0.1 10 6.8 0.0 2.4 2 0 0 2 2 2 0 Replication terminator protein DUF2639 PF11121.8 CCH61738.1 - 0.22 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) SR-25 PF10500.9 CCH61738.1 - 2.6 7.6 6.1 4.2 6.9 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAD-oxidase_C PF02913.19 CCH61739.1 - 5.2e-59 199.9 0.0 6.8e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCH61739.1 - 4.7e-35 120.4 0.0 7.3e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SR-25 PF10500.9 CCH61739.1 - 3.5 7.2 5.4 7 6.2 5.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aldo_ket_red PF00248.21 CCH61740.1 - 1.4e-38 132.8 0.1 2.9e-37 128.5 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0029 PF01205.19 CCH61741.1 - 5.7e-29 100.6 0.0 6.4e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Pmp3 PF01679.17 CCH61742.1 - 5.4e-21 74.5 5.6 7.6e-21 74.1 5.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Na_Ca_ex PF01699.24 CCH61743.1 - 2.3e-50 170.5 38.1 3.4e-25 88.8 11.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.6 CCH61743.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 YWFCY protein DUF2489 PF10675.9 CCH61743.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) ATP-synt_8 PF00895.20 CCH61743.1 - 0.49 10.9 0.1 0.49 10.9 0.1 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 IATP PF04568.12 CCH61745.1 - 1.4e-13 51.1 1.1 1.9e-13 50.7 1.1 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Cortex-I_coil PF09304.10 CCH61745.1 - 0.003 17.8 1.8 0.0037 17.4 1.8 1.2 1 0 0 1 1 1 1 Cortexillin I, coiled coil FbpA PF05833.11 CCH61745.1 - 0.0047 15.8 3.2 0.0046 15.8 3.2 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) P4Ha_N PF08336.11 CCH61745.1 - 0.028 14.4 2.5 0.048 13.7 2.5 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region AAA_23 PF13476.6 CCH61745.1 - 0.039 14.5 3.0 0.04 14.4 3.0 1.1 1 0 0 1 1 1 0 AAA domain MARVEL PF01284.23 CCH61746.1 - 1.4e-06 28.4 0.7 2.2e-06 27.8 0.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain tRNA-synt_2_TM PF16995.5 CCH61746.1 - 0.13 12.0 0.6 0.21 11.2 0.6 1.2 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase DUF2314 PF10077.9 CCH61747.1 - 0.021 14.9 1.9 0.053 13.6 1.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) DUF3824 PF12868.7 CCH61747.1 - 0.027 15.1 5.9 0.083 13.6 5.9 1.8 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Phage_Gp23 PF10669.9 CCH61747.1 - 0.067 13.5 5.3 0.15 12.4 5.3 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) NumbF PF06311.12 CCH61747.1 - 1.1 9.9 4.2 10 6.8 0.1 2.8 1 1 0 2 2 2 0 NUMB domain Ferlin_C PF16165.5 CCH61747.1 - 2.9 7.8 7.0 7.9 6.4 7.0 1.7 1 0 0 1 1 1 0 Ferlin C-terminus Atrophin-1 PF03154.15 CCH61747.1 - 3.2 5.9 9.7 4.8 5.3 9.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family Metallophos PF00149.28 CCH61748.1 - 8.4e-33 114.6 0.3 1.4e-32 113.9 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.17 CCH61749.1 - 2.5e-58 197.0 3.6 2.9e-58 196.9 3.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor R3H PF01424.22 CCH61750.1 - 5.6e-09 35.9 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 CCH61750.1 - 0.0097 16.6 4.0 0.0097 16.6 4.0 4.9 5 1 1 6 6 6 1 SUZ domain Ufd2P_core PF10408.9 CCH61751.1 - 4.5e-194 646.6 27.4 4.5e-194 646.6 27.4 1.7 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 CCH61751.1 - 1.1e-27 95.9 0.7 5.3e-27 93.8 0.7 2.3 1 0 0 1 1 1 1 U-box domain Peptidase_M32 PF02074.15 CCH61751.1 - 0.0021 16.9 0.2 0.0036 16.1 0.2 1.3 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase TRAPPC-Trs85 PF12739.7 CCH61751.1 - 0.069 12.1 0.1 0.14 11.1 0.1 1.5 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Tfb5 PF06331.12 CCH61751.1 - 0.25 11.4 2.3 0.62 10.1 0.3 2.9 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 Ribosomal_L29 PF00831.23 CCH61752.1 - 8.1e-17 60.9 10.4 9.6e-17 60.7 3.4 2.1 2 0 0 2 2 2 2 Ribosomal L29 protein FAM167 PF11652.8 CCH61752.1 - 0.037 14.5 1.2 0.059 13.9 1.2 1.7 1 1 0 1 1 1 0 FAM167 Arf PF00025.21 CCH61753.1 - 1.3e-77 259.2 0.0 1.4e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCH61753.1 - 1.8e-14 54.0 0.1 2.4e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCH61753.1 - 7e-14 51.7 0.0 7.4e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCH61753.1 - 2.4e-13 49.9 0.0 2.9e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCH61753.1 - 7.7e-12 45.0 0.8 6.5e-08 32.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCH61753.1 - 7.3e-10 38.6 0.0 9.1e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCH61753.1 - 2.2e-05 24.5 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCH61753.1 - 0.0084 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NACHT PF05729.12 CCH61753.1 - 0.027 14.4 0.4 2.7 7.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 CCH61753.1 - 0.034 13.7 0.0 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CCH61753.1 - 0.043 14.0 0.4 0.092 12.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCH61753.1 - 0.05 14.1 0.0 0.083 13.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.18 CCH61753.1 - 0.056 12.7 0.1 0.079 12.3 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 CCH61753.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCH61753.1 - 0.097 12.6 0.0 13 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 CCH61753.1 - 0.11 11.4 0.1 8.1 5.3 0.0 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CCH61753.1 - 0.11 13.0 0.1 0.16 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain DUF5099 PF17025.5 CCH61754.1 - 0.0091 16.4 0.0 0.038 14.4 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5099) Sugar_tr PF00083.24 CCH61755.1 - 2.2e-124 415.8 25.4 2.6e-124 415.5 25.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH61755.1 - 2.1e-16 59.8 31.4 2.1e-16 59.8 31.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CarS-like PF01864.17 CCH61755.1 - 2.8 7.9 10.6 0.12 12.3 3.7 2.1 2 0 0 2 2 2 0 CDP-archaeol synthase Sec31 PF11549.8 CCH61756.1 - 5.6e-24 83.8 5.1 2e-23 82.0 5.1 2.1 1 0 0 1 1 1 1 Protein transport protein SEC31 ANAPC4_WD40 PF12894.7 CCH61756.1 - 4.7e-09 36.4 1.7 0.056 13.8 0.1 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH61756.1 - 7.4e-07 29.8 8.6 0.055 14.4 0.0 6.2 6 1 0 6 6 6 2 WD domain, G-beta repeat Prp18 PF02840.15 CCH61756.1 - 1.9e-06 28.0 1.7 3.9e-06 27.0 0.3 2.3 2 1 0 2 2 2 1 Prp18 domain SRA1 PF07304.11 CCH61756.1 - 4.6e-05 23.2 0.0 4.6e-05 23.2 0.0 3.1 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 CCH61756.1 - 0.0012 18.5 0.9 0.0032 17.2 0.9 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 MmlI PF09448.10 CCH61756.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase ERp29 PF07749.12 CCH61756.1 - 1.3 9.9 9.2 2.9 8.8 0.1 3.7 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain CHCH PF06747.13 CCH61757.1 - 0.00022 21.3 4.4 0.00042 20.4 4.4 1.5 1 0 0 1 1 1 1 CHCH domain Helo_like_N PF17111.5 CCH61757.1 - 0.024 14.0 0.2 0.03 13.7 0.2 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Ndufs5 PF10200.9 CCH61757.1 - 0.038 14.3 0.3 0.048 13.9 0.3 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Scm3 PF10384.9 CCH61758.1 - 4.1e-18 64.9 1.5 4.1e-18 64.9 1.5 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 RNA_pol_Rpb1_1 PF04997.12 CCH61759.1 - 7.2e-117 390.2 0.2 1.7e-116 389.0 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CCH61759.1 - 1.8e-105 352.2 0.2 2.7e-105 351.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCH61759.1 - 9e-78 260.2 0.1 3.3e-77 258.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CCH61759.1 - 2.3e-60 203.7 0.3 5.2e-60 202.6 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CCH61759.1 - 2.4e-46 157.1 4.3 4.7e-46 156.1 4.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CCH61759.1 - 6.4e-46 156.1 0.1 1.9e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCH61759.1 - 1.2e-35 121.7 0.1 3.7e-35 120.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CCH61759.1 - 2.6e-13 49.6 288.0 0.011 16.0 9.9 14.6 2 1 23 25 25 25 22 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.6 CCH61759.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BPL_N PF09825.9 CCH61760.1 - 1.1e-117 393.4 0.0 1.3e-117 393.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CCH61760.1 - 3e-20 72.5 0.0 5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CCH61760.1 - 1.3e-13 50.6 0.1 2.6e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DJ-1_PfpI PF01965.24 CCH61760.1 - 0.0035 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 CCH61760.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Cpn60_TCP1 PF00118.24 CCH61761.1 - 1.3e-144 482.6 14.5 1.4e-144 482.4 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family D123 PF07065.14 CCH61762.1 - 1.3e-112 376.0 10.4 1.3e-112 376.0 10.4 1.4 2 0 0 2 2 2 1 D123 Hydrolase_3 PF08282.12 CCH61762.1 - 0.077 12.7 2.2 0.088 12.5 0.3 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.21 CCH61763.1 - 1.2e-43 148.6 0.5 3.2e-43 147.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 GlgS PF08971.11 CCH61763.1 - 0.039 14.0 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein Nodulin_late PF07127.11 CCH61763.1 - 0.25 11.7 1.3 0.5 10.7 1.3 1.5 1 0 0 1 1 1 0 Late nodulin protein Chitin_bind_1 PF00187.19 CCH61763.1 - 2.1 8.9 12.9 4.1 8.0 12.9 1.4 1 0 0 1 1 1 0 Chitin recognition protein ApbA_C PF08546.11 CCH61764.1 - 8.9e-23 80.8 0.0 1.4e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CCH61764.1 - 4.8e-21 75.0 0.0 9.8e-21 74.0 0.0 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 CCH61764.1 - 0.046 12.9 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CCH61764.1 - 0.06 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Rossmann-like PF10727.9 CCH61764.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain Sacchrp_dh_NADP PF03435.18 CCH61764.1 - 0.17 12.2 0.8 0.7 10.2 0.8 2.1 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 CCH61764.1 - 0.18 12.4 0.6 0.41 11.2 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CCH61764.1 - 0.28 10.7 0.5 0.42 10.1 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Coatomer_WDAD PF04053.14 CCH61765.1 - 6.2e-129 430.9 8.3 9.7e-129 430.3 8.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CCH61765.1 - 1.5e-85 287.4 0.1 2.3e-85 286.8 0.1 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CCH61765.1 - 3e-40 135.5 19.5 3.3e-08 34.1 0.3 7.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61765.1 - 2.8e-13 50.0 1.0 1.7e-05 25.0 0.0 6.0 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCH61765.1 - 5.6e-06 25.3 5.2 0.076 11.7 0.1 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CCH61765.1 - 6.2e-06 26.2 2.4 0.22 11.4 0.0 4.4 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A ENTH PF01417.20 CCH61765.1 - 0.088 12.9 0.4 0.3 11.1 0.4 1.9 1 0 0 1 1 1 0 ENTH domain HALZ PF02183.18 CCH61766.1 - 0.034 14.4 2.7 0.034 14.4 2.7 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper VD10_N PF08476.10 CCH61766.1 - 0.24 11.1 0.2 0.24 11.1 0.2 1.9 2 0 0 2 2 2 0 Viral D10 N-terminal Spectrin PF00435.21 CCH61766.1 - 1.1 9.8 10.5 3.2 8.3 4.0 2.5 2 1 0 2 2 2 0 Spectrin repeat Ly49 PF08391.10 CCH61766.1 - 2.8 8.3 7.7 0.79 10.1 4.0 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PCI PF01399.27 CCH61767.1 - 4.8e-23 81.7 3.4 4.9e-23 81.6 0.5 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CCH61767.1 - 2.1e-14 53.3 4.3 2.1e-14 53.3 4.3 1.9 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Nop14 PF04147.12 CCH61768.1 - 6.3e-167 557.4 64.3 3.7e-101 339.8 7.6 2.5 1 1 1 2 2 2 2 Nop14-like family DUF4798 PF16055.5 CCH61768.1 - 0.062 13.6 0.1 0.062 13.6 0.1 4.2 5 1 1 6 6 6 0 Domain of unknown function (DUF4798) APG9 PF04109.16 CCH61769.1 - 1.3e-192 641.1 23.4 1.7e-192 640.7 23.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.14 CCH61770.1 - 2.4e-26 93.0 0.3 2.4e-26 93.0 0.3 2.6 2 1 0 2 2 2 1 RNA polymerase III RPC4 Sas10 PF09368.10 CCH61771.1 - 1.7e-28 98.9 12.6 1.7e-28 98.9 12.6 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CCH61771.1 - 2.9e-07 31.0 0.3 1.6e-06 28.6 0.3 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pyr_excise PF03013.14 CCH61771.1 - 0.028 14.4 0.8 0.12 12.3 0.8 2.2 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Transposase_22 PF02994.14 CCH61771.1 - 7.9 6.7 8.6 0.91 9.7 1.1 3.0 3 0 0 3 3 3 0 L1 transposable element RBD-like domain MutS_V PF00488.21 CCH61772.1 - 4.5e-46 157.2 0.1 3.2e-45 154.5 0.0 2.4 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CCH61772.1 - 4.3e-20 72.8 5.5 4.3e-20 72.8 5.5 2.7 3 1 0 3 3 3 1 MutS domain III AAA_14 PF13173.6 CCH61772.1 - 0.0088 16.1 10.2 0.32 11.0 0.0 4.8 3 1 2 5 5 5 2 AAA domain AAA_16 PF13191.6 CCH61772.1 - 0.097 13.0 0.0 3.5 8.0 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CCH61772.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_IV PF05190.18 CCH61772.1 - 0.14 12.5 2.7 1.3 9.4 2.7 2.6 1 1 0 1 1 1 0 MutS family domain IV Cyclin_N PF00134.23 CCH61773.1 - 1.1e-44 151.2 0.1 2.5e-44 150.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCH61773.1 - 3.3e-38 130.4 0.2 8e-38 129.2 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain BUD22 PF09073.10 CCH61773.1 - 0.46 9.8 15.9 0.71 9.1 15.9 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CCH61773.1 - 1.8 6.7 26.7 2.6 6.2 26.7 1.1 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.32 CCH61774.1 - 1.1e-09 38.7 3.1 0.013 16.4 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61774.1 - 0.00065 19.9 0.1 2.3 8.6 0.0 3.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CCH61776.1 - 1.6e-69 234.2 0.0 2.4e-69 233.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH61776.1 - 1.3e-40 139.4 0.0 2e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH61776.1 - 3.6e-05 22.9 1.7 0.00019 20.5 0.9 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CCH61776.1 - 0.00063 18.6 0.0 0.0016 17.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCH61776.1 - 0.012 14.9 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 CCH61776.1 - 0.43 10.1 0.0 0.43 10.1 0.0 2.8 3 0 0 3 3 3 0 RIO1 family DEAD PF00270.29 CCH61777.1 - 5.1e-44 150.1 0.1 8.4e-44 149.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61777.1 - 4.1e-29 101.2 2.4 1.8e-28 99.1 0.4 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Phage_integrase PF00589.22 CCH61777.1 - 0.14 12.0 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 2 0 Phage integrase family PNP_UDP_1 PF01048.20 CCH61778.1 - 8.9e-46 156.0 0.0 1.1e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Zip PF02535.22 CCH61779.1 - 8.9e-74 248.7 0.0 1.3e-73 248.1 0.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.13 CCH61779.1 - 5.5e-05 22.8 0.6 0.0026 17.4 0.3 2.3 2 0 0 2 2 2 2 UNC-50 family WD40 PF00400.32 CCH61780.1 - 7.6e-21 74.0 19.2 2.5e-05 25.0 0.5 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61780.1 - 2.3e-05 24.6 5.2 0.33 11.3 0.2 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 CCH61780.1 - 0.13 12.4 0.0 14 5.9 0.0 3.1 3 0 0 3 3 3 0 YmzC-like protein NAD_binding_7 PF13241.6 CCH61781.1 - 2.5e-20 72.9 0.0 3.6e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CCH61781.1 - 3.4e-06 26.6 0.0 6.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CCH61781.1 - 0.012 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 CCH61781.1 - 0.029 14.4 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 CCH61781.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CBS PF00571.28 CCH61782.1 - 1.3e-23 83.1 3.4 4.6e-06 27.0 0.1 5.3 5 0 0 5 5 5 5 CBS domain Cytomega_UL20A PF05984.12 CCH61782.1 - 0.05 13.9 0.2 0.095 13.0 0.2 1.4 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein UQ_con PF00179.26 CCH61784.1 - 8.2e-51 171.3 0.1 9.7e-51 171.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCH61784.1 - 0.013 15.8 0.1 0.036 14.4 0.1 1.8 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 CCH61784.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 CCH61784.1 - 0.048 13.5 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain Drc1-Sld2 PF11719.8 CCH61784.1 - 0.82 9.2 6.1 1 8.8 6.1 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NOA36 PF06524.12 CCH61784.1 - 4.2 6.6 10.2 5 6.4 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein BCDHK_Adom3 PF10436.9 CCH61785.1 - 2.4e-28 99.0 0.9 4.3e-28 98.2 0.9 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCH61785.1 - 4.8e-05 23.8 0.0 0.012 16.1 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_Treg PF04761.12 CCH61785.1 - 0.027 14.6 0.0 0.37 10.9 0.0 2.9 4 0 0 4 4 4 0 Lactococcus bacteriophage putative transcription regulator Kinetochor_Ybp2 PF08568.10 CCH61786.1 - 1.5e-77 261.6 31.9 1.7e-77 261.4 31.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DASH_Duo1 PF08651.10 CCH61787.1 - 3.6e-18 65.1 2.7 3.6e-18 65.1 2.7 2.1 2 0 0 2 2 2 1 DASH complex subunit Duo1 DASH_Spc34 PF08657.10 CCH61787.1 - 0.19 11.5 11.4 0.076 12.8 7.8 2.1 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF2400 PF09674.10 CCH61787.1 - 0.36 10.8 3.1 0.35 10.8 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) DUF2098 PF09871.9 CCH61787.1 - 4.2 7.8 7.7 3.1 8.2 3.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Uds1 PF15456.6 CCH61787.1 - 7.6 6.7 9.9 0.27 11.4 2.5 2.3 1 1 2 3 3 3 0 Up-regulated During Septation CPSase_L_D2 PF02786.17 CCH61788.1 - 7.5e-82 273.9 0.5 1.2e-81 273.3 0.5 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCH61788.1 - 1.2e-65 221.0 0.0 2.3e-65 220.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CCH61788.1 - 8.6e-36 122.8 0.0 2.3e-35 121.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCH61788.1 - 1.3e-30 105.6 0.0 5.4e-30 103.7 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCH61788.1 - 9.9e-23 81.0 0.0 2.4e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CCH61788.1 - 3.7e-18 65.1 2.6 1.4e-17 63.3 2.6 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CCH61788.1 - 1.4e-07 31.3 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CCH61788.1 - 2.5e-07 30.4 0.6 0.0088 15.8 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 CCH61788.1 - 8.7e-07 28.7 0.1 1.8e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CCH61788.1 - 4.4e-06 26.8 0.0 9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CCH61788.1 - 6.1e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 CCH61788.1 - 0.00063 19.1 0.0 0.0019 17.5 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 CCH61788.1 - 0.0033 18.1 0.1 5.3 7.8 0.0 3.3 3 1 1 4 4 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 CCH61788.1 - 0.0087 15.3 0.0 0.59 9.3 0.0 2.7 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 CCH61788.1 - 0.068 12.8 0.2 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_YheCD PF14398.6 CCH61788.1 - 0.085 12.1 0.0 5.9 6.1 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp Med31 PF05669.12 CCH61789.1 - 8.4e-22 77.0 0.0 1e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.9 CCH61790.1 - 2.3e-49 168.2 2.7 8.1e-42 143.4 0.0 2.1 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM SUa-2TM PF18179.1 CCH61790.1 - 0.016 14.5 4.6 0.033 13.5 4.6 1.5 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain PAP2 PF01569.21 CCH61790.1 - 0.034 13.9 0.5 0.034 13.9 0.5 2.3 2 0 0 2 2 2 0 PAP2 superfamily Acatn PF13000.7 CCH61791.1 - 1.8e-250 832.2 26.5 2.6e-250 831.6 26.5 1.2 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 MTHFR PF02219.17 CCH61792.1 - 2.4e-102 342.1 0.1 2.7e-101 338.7 0.1 2.1 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_11 PF08241.12 CCH61793.1 - 0.002 18.7 0.0 0.0055 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AAA_2 PF07724.14 CCH61794.1 - 1.3e-34 119.8 4.1 1.2e-33 116.6 1.5 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CCH61794.1 - 7.8e-13 49.0 0.8 1.6e-12 48.0 0.1 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CCH61794.1 - 9.8e-08 32.0 0.0 3.9e-07 30.0 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CCH61794.1 - 9.5e-07 28.9 0.2 2.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCH61794.1 - 8.8e-05 22.8 1.6 0.003 17.8 0.5 3.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCH61794.1 - 0.0013 18.2 0.0 0.021 14.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CCH61794.1 - 0.0023 18.3 0.2 0.0088 16.4 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CCH61794.1 - 0.0027 17.3 0.0 0.0058 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCH61794.1 - 0.0084 15.8 0.0 1 9.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CCH61794.1 - 0.009 16.1 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 CCH61794.1 - 0.012 15.6 0.7 0.038 14.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCH61794.1 - 0.024 14.4 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 CCH61794.1 - 0.026 14.3 0.3 0.078 12.7 0.3 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 CCH61794.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 CCH61794.1 - 0.039 13.9 0.2 2.2 8.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain ALMT PF11744.8 CCH61794.1 - 0.85 8.4 4.6 2.4 6.9 1.4 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter GIY-YIG PF01541.24 CCH61795.1 - 2.3e-12 47.0 0.1 4.7e-12 46.0 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Mon1 PF03164.14 CCH61796.1 - 1.4e-131 439.4 21.3 2.7e-131 438.4 21.3 1.5 1 0 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_S5 PF00333.20 CCH61797.1 - 8.9e-26 89.7 3.1 6.5e-25 86.9 2.2 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CCH61797.1 - 3.1e-23 81.0 0.0 5.6e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Nab2 PF11517.8 CCH61798.1 - 2.6e-49 165.7 3.7 4.3e-49 165.0 3.7 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Nab2p_Zf1 PF18260.1 CCH61798.1 - 3.5e-16 58.8 10.1 3.5e-16 58.8 10.1 3.4 3 0 0 3 3 3 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 zf-CCCH_2 PF14608.6 CCH61798.1 - 1.9e-15 56.7 72.8 8.9e-05 22.8 4.4 7.3 7 0 0 7 7 7 5 RNA-binding, Nab2-type zinc finger Imm19 PF15563.6 CCH61798.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 19 DUF2508 PF10704.9 CCH61798.1 - 0.13 12.4 0.4 0.42 10.8 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Glyco_tranf_2_2 PF10111.9 CCH61798.1 - 0.19 11.2 0.1 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 TFIIA PF03153.13 CCH61798.1 - 0.47 10.4 17.3 0.094 12.7 11.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3847 PF12958.7 CCH61798.1 - 1.7 8.8 8.8 11 6.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3847) FoP_duplication PF13865.6 CCH61798.1 - 6.6 7.4 12.2 20 5.8 12.2 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 OB_NTP_bind PF07717.16 CCH61799.1 - 2.7e-22 78.9 0.0 1e-21 77.1 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CCH61799.1 - 4.7e-21 75.1 0.0 1.2e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCH61799.1 - 1.8e-11 44.4 0.0 4.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCH61799.1 - 4.8e-10 39.5 0.2 8.4e-10 38.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH61799.1 - 1.4e-06 28.7 0.3 4.8e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CCH61799.1 - 3.2e-05 23.7 0.1 9.1e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CCH61799.1 - 0.00023 21.5 0.2 0.00042 20.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CCH61799.1 - 0.0005 20.1 0.2 0.00099 19.1 0.2 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 CCH61799.1 - 0.00062 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CCH61799.1 - 0.0018 18.8 0.1 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CCH61799.1 - 0.0025 17.8 0.1 0.28 11.2 0.1 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CCH61799.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CCH61799.1 - 0.024 14.1 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 CCH61799.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 CCH61799.1 - 0.2 11.8 0.4 1.2 9.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain Peptidase_C12 PF01088.21 CCH61800.1 - 1.8e-46 158.5 0.0 2.1e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.16 CCH61801.1 - 9.6e-18 64.6 4.7 8.3e-16 58.2 4.7 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CCH61801.1 - 0.00069 19.6 1.5 0.0014 18.6 1.1 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family ESCRT-II PF05871.12 CCH61802.1 - 5.5e-45 153.0 1.0 6.7e-45 152.8 1.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Myb_CC_LHEQLE PF14379.6 CCH61803.1 - 0.0013 18.4 0.1 0.12 12.1 0.0 2.7 3 0 0 3 3 3 1 MYB-CC type transfactor, LHEQLE motif Fmp27_WPPW PF10359.9 CCH61803.1 - 0.012 14.4 1.6 0.014 14.2 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2408 PF10303.9 CCH61803.1 - 0.016 15.8 2.5 0.024 15.2 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) MerR-DNA-bind PF09278.11 CCH61803.1 - 0.019 15.5 0.4 0.019 15.5 0.4 2.1 2 0 0 2 2 2 0 MerR, DNA binding Syntaxin-6_N PF09177.11 CCH61803.1 - 0.042 14.4 1.6 0.048 14.2 0.3 1.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 CCH61803.1 - 0.72 10.0 7.1 0.67 10.1 0.2 3.1 3 1 1 4 4 4 0 bZIP transcription factor Prefoldin PF02996.17 CCH61803.1 - 4 7.4 10.2 0.97 9.4 0.9 3.2 3 1 1 4 4 4 0 Prefoldin subunit CTP_synth_N PF06418.14 CCH61804.1 - 9.7e-125 415.2 0.2 1.3e-124 414.8 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CCH61804.1 - 1.3e-56 191.4 0.0 2e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCH61804.1 - 0.00037 20.3 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 Transket_pyr PF02779.24 CCH61804.1 - 0.13 11.9 0.0 0.7 9.5 0.0 2.0 1 1 1 2 2 2 0 Transketolase, pyrimidine binding domain ER_lumen_recept PF00810.18 CCH61806.1 - 9.6e-48 162.7 13.4 9.6e-48 162.7 13.4 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor Proteasome PF00227.26 CCH61807.1 - 1.2e-35 122.8 0.0 8.5e-35 120.0 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit KilA-N PF04383.13 CCH61809.1 - 0.093 12.6 1.5 0.16 11.8 1.5 1.4 1 0 0 1 1 1 0 KilA-N domain Peptidase_M16_C PF05193.21 CCH61810.1 - 6.9e-20 71.8 0.1 6.9e-20 71.8 0.1 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCH61810.1 - 1.7e-17 63.8 0.4 2.8e-17 63.1 0.4 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.11 CCH61811.1 - 4.1e-46 157.9 53.1 4.1e-46 157.9 53.1 3.8 1 1 2 3 3 3 1 PPP4R2 DUF1133 PF06576.11 CCH61811.1 - 0.028 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) ASFV_J13L PF05568.11 CCH61811.1 - 2.1 8.1 8.0 3.4 7.4 8.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_S7 PF00177.21 CCH61812.1 - 2.4e-33 114.9 0.0 3.7e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Apolipoprotein PF01442.18 CCH61812.1 - 0.0015 18.5 0.1 0.005 16.7 0.1 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CCH61812.1 - 0.078 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) VanZ PF04892.12 CCH61813.1 - 2.5e-08 34.6 2.6 3.6e-08 34.1 2.6 1.2 1 0 0 1 1 1 1 VanZ like family DUF3836 PF12930.7 CCH61813.1 - 0.079 12.7 0.6 0.11 12.2 0.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF3836) Adeno_E3_14_5 PF04834.12 CCH61813.1 - 0.093 13.3 0.2 0.19 12.3 0.1 1.6 1 1 0 1 1 1 0 Early E3 14.5 kDa protein EF-hand_4 PF12763.7 CCH61814.1 - 4e-34 116.7 0.1 6.2e-11 42.2 0.0 4.1 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 CCH61814.1 - 2.2e-10 40.2 0.0 5.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 CCH61814.1 - 7.4e-10 37.7 0.3 0.0001 21.6 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CCH61814.1 - 1.2e-07 31.1 0.0 0.027 14.4 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CCH61814.1 - 1.5e-06 28.5 0.3 0.065 13.7 0.0 4.6 4 0 0 4 4 4 2 EF-hand domain pair UBA_4 PF14555.6 CCH61814.1 - 0.0001 22.0 0.2 0.00023 20.9 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CCH61814.1 - 0.012 15.3 0.4 0.1 12.2 0.1 2.7 2 0 0 2 2 2 0 TAP C-terminal domain TPR_MLP1_2 PF07926.12 CCH61814.1 - 6.8 6.8 58.7 4.3 7.4 7.0 4.6 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein CMD PF02627.20 CCH61815.1 - 5.7e-05 23.1 0.0 0.00043 20.3 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family GrpB PF04229.14 CCH61815.1 - 0.05 13.8 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 GrpB protein PRESAN PF09687.10 CCH61815.1 - 1 9.9 8.3 0.3 11.6 0.6 2.7 2 1 1 3 3 3 0 Plasmodium RESA N-terminal Myotub-related PF06602.14 CCH61816.1 - 1.4e-136 455.1 8.9 2.4e-136 454.3 8.9 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 CCH61816.1 - 0.037 13.8 0.1 0.037 13.8 0.1 3.1 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCH61816.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PH_BEACH PF14844.6 CCH61816.1 - 0.44 10.7 2.5 4.9 7.3 2.5 2.7 1 1 0 1 1 1 0 PH domain associated with Beige/BEACH Yippee-Mis18 PF03226.14 CCH61817.1 - 5.2e-14 52.3 4.6 8.4e-14 51.7 4.6 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNAP PF14938.6 CCH61818.1 - 1.6e-107 359.2 13.5 1.8e-107 359.0 13.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Foie-gras_1 PF11817.8 CCH61818.1 - 7.2e-06 25.8 0.2 1.1e-05 25.2 0.2 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_6 PF13174.6 CCH61818.1 - 0.0011 19.4 2.8 2.8 8.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCH61818.1 - 0.0032 17.7 3.2 1 9.7 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH61818.1 - 0.0039 17.1 0.8 0.12 12.5 0.1 3.6 4 1 0 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 CCH61818.1 - 0.017 14.2 5.7 0.041 13.0 2.1 2.3 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_2 PF07719.17 CCH61818.1 - 0.02 15.0 11.1 3.6 7.9 0.6 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CCH61818.1 - 4.9 7.3 9.9 4.7 7.4 0.3 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CPSase_L_D2 PF02786.17 CCH61819.1 - 5.7e-107 356.0 0.0 1.1e-81 273.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CCH61819.1 - 3.4e-36 124.3 2.2 5.8e-36 123.5 1.3 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CCH61819.1 - 7.9e-16 58.1 0.0 6e-07 29.2 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCH61819.1 - 1e-13 51.2 0.0 1.7e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 CCH61819.1 - 1e-11 44.8 0.1 8.5e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 CCH61819.1 - 0.061 12.8 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain MGS PF02142.22 CCH61819.1 - 0.12 12.6 0.1 0.64 10.2 0.1 2.4 2 0 0 2 2 2 0 MGS-like domain DUF5137 PF17220.3 CCH61820.1 - 1.1e-25 90.2 6.4 1.6e-25 89.8 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF5137) Pap_E4 PF02711.14 CCH61820.1 - 0.48 11.4 5.0 0.37 11.8 2.4 1.8 1 1 1 2 2 2 0 E4 protein Na_Ca_ex PF01699.24 CCH61821.1 - 7e-43 146.2 44.9 4.9e-25 88.2 14.8 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein TRAM_LAG1_CLN8 PF03798.16 CCH61822.1 - 7.8e-32 110.6 24.3 7.8e-32 110.6 24.3 1.9 2 0 0 2 2 2 1 TLC domain DUF1240 PF06836.12 CCH61822.1 - 4.6 7.8 15.3 0.13 12.9 6.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) TRAM_LAG1_CLN8 PF03798.16 CCH61823.1 - 4.6e-23 82.0 19.1 4.6e-23 82.0 19.1 2.0 2 1 0 2 2 2 1 TLC domain Peptidase_M48_N PF16491.5 CCH61824.1 - 4e-60 202.8 11.8 4e-60 202.8 11.8 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CCH61824.1 - 3.4e-42 144.5 0.1 7.1e-42 143.4 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 CCH61824.1 - 0.0021 17.6 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 Predicted Zn-dependent protease (DUF2268) Peptidase_M56 PF05569.11 CCH61824.1 - 0.02 14.1 1.1 0.04 13.1 1.1 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 CCH61824.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 SprT-like family PCI PF01399.27 CCH61825.1 - 9e-21 74.4 1.2 2.1e-20 73.2 0.5 2.1 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 CCH61825.1 - 1.1e-20 73.8 0.2 2.2e-20 72.9 0.2 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal Med17 PF10156.9 CCH61826.1 - 7.3e-174 578.8 18.3 9.8e-174 578.4 18.3 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Npun_R1517 PF18068.1 CCH61826.1 - 0.1 13.0 3.4 0.12 12.7 0.0 2.9 3 1 0 3 3 3 0 Npun R1517 Ilm1 PF10311.9 CCH61827.1 - 1.5e-12 47.5 10.9 2.1e-07 30.8 4.0 2.1 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 Astro_capsid_p PF12226.8 CCH61827.1 - 0.071 12.3 11.3 0.08 12.1 11.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 CCH61827.1 - 0.35 10.0 8.1 0.49 9.6 8.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CCH61827.1 - 9.1 4.4 15.6 11 4.2 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein P5CR_dimer PF14748.6 CCH61828.1 - 1.8e-33 114.9 0.4 3.3e-33 114.0 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CCH61828.1 - 3.7e-09 37.0 0.1 8.6e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CCH61828.1 - 0.0012 18.5 0.4 0.0035 17.0 0.4 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CCH61828.1 - 0.026 14.5 0.2 0.062 13.3 0.2 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ATP-synt_ab PF00006.25 CCH61829.1 - 4.6e-62 209.4 0.0 6.9e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCH61829.1 - 1.9e-23 82.8 0.8 5.6e-23 81.2 0.8 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 CCH61829.1 - 0.0019 17.6 0.2 0.0034 16.8 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 CCH61829.1 - 0.016 14.4 0.6 0.078 12.2 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 CCH61829.1 - 0.036 14.0 0.1 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 NACHT domain T3SS_ATPase_C PF18269.1 CCH61829.1 - 0.037 13.9 0.6 0.21 11.5 0.6 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain RsgA_GTPase PF03193.16 CCH61829.1 - 0.043 13.7 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CCH61829.1 - 0.062 13.7 0.1 0.7 10.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH61829.1 - 0.069 13.5 0.2 0.33 11.3 0.2 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 CCH61829.1 - 0.11 12.8 0.5 0.48 10.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCH61829.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CCH61829.1 - 0.18 11.8 0.1 0.46 10.5 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 CCH61829.1 - 0.26 10.7 0.1 0.51 9.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Carn_acyltransf PF00755.20 CCH61830.1 - 2.8e-107 359.8 0.2 3.5e-106 356.2 0.2 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Colicin_immun PF09204.10 CCH61830.1 - 1.8 9.2 7.5 0.86 10.2 2.3 2.7 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Zn_clus PF00172.18 CCH61831.1 - 1.6e-08 34.5 7.8 1.6e-08 34.5 7.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P_C PF06640.11 CCH61831.1 - 0.36 10.9 1.5 4.8 7.3 0.1 2.3 2 0 0 2 2 2 0 P protein C-terminus Phage_TAC_12 PF12363.8 CCH61831.1 - 0.79 10.2 4.5 0.75 10.2 1.6 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Fmp27_WPPW PF10359.9 CCH61833.1 - 5e-111 371.9 4.8 5e-111 371.9 4.8 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CCH61833.1 - 3.6e-69 233.9 9.7 4.2e-47 161.1 0.1 3.4 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27 PF10344.9 CCH61833.1 - 6.6e-61 206.5 68.9 2.2e-50 171.7 61.1 2.5 2 0 0 2 2 2 2 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 CCH61833.1 - 2.9e-55 186.6 1.1 7.6e-54 182.0 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCH61833.1 - 3.1e-51 173.3 2.8 3.1e-51 173.3 2.8 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCH61833.1 - 7.3e-30 103.7 0.8 7e-29 100.6 0.0 3.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain GH43_C PF16369.5 CCH61834.1 - 0.077 13.6 0.0 0.52 11.0 0.0 2.3 2 0 0 2 2 2 0 C-terminal lipocalin-like domain Ras PF00071.22 CCH61835.1 - 2e-54 183.5 0.0 2.4e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH61835.1 - 3.4e-21 75.7 0.0 5.6e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH61835.1 - 1.9e-08 34.0 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCH61835.1 - 0.068 12.6 0.0 0.099 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCH61835.1 - 0.19 11.0 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.21 CCH61836.1 - 1.7e-21 75.7 0.4 2.6e-21 75.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.19 CCH61837.1 - 6.6e-38 130.5 0.0 8.4e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ANAPC4_WD40 PF12894.7 CCH61838.1 - 6e-06 26.5 0.3 0.093 13.0 0.0 3.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Na_trans_assoc PF06512.13 CCH61838.1 - 5e-05 23.7 3.8 0.021 15.1 0.0 2.8 1 1 1 2 2 2 1 Sodium ion transport-associated PQQ_3 PF13570.6 CCH61838.1 - 0.0033 17.9 0.0 14 6.4 0.0 3.5 3 0 0 3 3 3 2 PQQ-like domain WD40 PF00400.32 CCH61838.1 - 0.029 15.3 0.2 9.9 7.2 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat SDA1 PF05285.12 CCH61838.1 - 1 8.7 26.8 2.6 7.4 26.8 1.7 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CCH61838.1 - 1.8 6.8 23.7 3.1 6.0 23.7 1.3 1 0 0 1 1 1 0 CDC45-like protein PH_4 PF15404.6 CCH61839.1 - 2e-70 236.3 0.0 2e-70 236.3 0.0 3.1 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 CCH61839.1 - 6.8e-21 73.7 0.2 2.5e-20 71.9 0.2 2.1 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 CCH61839.1 - 0.75 10.3 11.1 1.4 9.5 0.1 4.9 5 0 0 5 5 5 0 PH domain Rad51 PF08423.11 CCH61840.1 - 4.1e-114 380.1 0.1 9.5e-114 378.9 0.0 1.6 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 CCH61840.1 - 1.2e-09 38.0 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CCH61840.1 - 1.9e-07 30.7 0.3 6.8e-07 28.9 0.0 2.1 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.6 CCH61840.1 - 2e-06 28.3 0.9 1.1e-05 25.9 0.2 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.6 CCH61840.1 - 4.3e-06 26.4 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain CAMSAP_CKK PF08683.11 CCH61840.1 - 0.06 13.5 0.3 0.28 11.4 0.0 2.0 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated RNA_pol_A_CTD PF03118.15 CCH61840.1 - 0.24 11.2 1.3 0.32 10.8 0.3 1.7 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Serinc PF03348.15 CCH61841.1 - 5.7e-136 453.9 15.1 6.8e-136 453.6 15.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Telomerase_RBD PF12009.8 CCH61841.1 - 0.51 10.4 3.0 0.22 11.6 0.5 1.7 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain TMEM173 PF15009.6 CCH61841.1 - 1.2 8.3 7.0 0.18 10.9 3.1 1.6 2 0 0 2 2 2 0 Transmembrane protein 173 DUF1129 PF06570.11 CCH61841.1 - 1.5 8.3 13.6 0.2 11.1 4.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3302 PF11742.8 CCH61842.1 - 0.011 15.9 0.3 0.014 15.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) MFS_1 PF07690.16 CCH61843.1 - 7.9e-44 150.0 47.2 1.2e-43 149.4 47.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH61843.1 - 2.4e-14 53.0 14.8 2.4e-14 53.0 14.8 3.3 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CCH61843.1 - 5.8e-06 25.0 20.3 8.9e-06 24.4 20.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5392 PF17370.2 CCH61843.1 - 0.048 13.7 1.1 8.2 6.5 0.1 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5392) Sulfate_transp PF00916.20 CCH61844.1 - 7.1e-102 341.0 14.2 9.1e-102 340.6 14.2 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCH61844.1 - 2.3e-09 36.9 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CCH61844.1 - 0.00082 19.7 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF1509 PF07420.11 CCH61844.1 - 0.032 13.2 1.5 0.05 12.6 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF5411 PF17424.2 CCH61844.1 - 0.12 12.3 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5411) Aminotran_1_2 PF00155.21 CCH61845.1 - 1.4e-38 133.0 0.0 2.1e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Gaa1 PF04114.14 CCH61847.1 - 1e-116 391.0 14.5 3.6e-116 389.1 14.5 1.7 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component FixS PF03597.15 CCH61847.1 - 2.6 7.9 6.2 1.9 8.3 0.2 2.9 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type GTP_EFTU PF00009.27 CCH61848.1 - 2.4e-54 183.8 0.0 3.4e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCH61848.1 - 3.8e-39 133.5 0.0 7.8e-39 132.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCH61848.1 - 1.6e-13 50.9 1.2 1.6e-13 50.9 1.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH61848.1 - 0.00021 21.4 0.2 0.005 16.9 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Met_asp_mut_E PF06368.11 CCH61848.1 - 0.023 13.2 0.0 0.035 12.6 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) GTP_EFTU_D4 PF14578.6 CCH61848.1 - 0.085 12.8 2.1 0.1 12.5 0.5 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 HGTP_anticodon PF03129.20 CCH61850.1 - 2.4e-20 72.5 0.1 6.7e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCH61850.1 - 1.9e-06 28.0 0.0 6.3e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) InPase PF18823.1 CCH61850.1 - 0.14 11.9 0.1 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Inorganic Pyrophosphatase Tau95 PF09734.9 CCH61851.1 - 8.2e-34 117.4 0.3 8.2e-34 117.4 0.3 3.3 3 1 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CCH61851.1 - 4e-25 88.5 1.0 4e-25 88.5 1.0 2.3 2 0 0 2 2 2 1 Tau95 Triple barrel domain PP2C PF00481.21 CCH61852.1 - 8.9e-66 222.1 0.0 1.7e-59 201.6 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CCH61852.1 - 0.00021 21.0 0.0 0.001 18.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CCH61852.1 - 0.0062 16.5 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Glyco_transf_20 PF00982.21 CCH61853.1 - 3.1e-203 675.7 0.0 3.6e-203 675.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 CCH61853.1 - 5e-05 22.9 0.4 0.0043 16.6 0.1 3.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCH61853.1 - 0.00012 22.5 0.0 0.00033 21.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 YopH_N PF09013.10 CCH61853.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 YopH, N-terminal Retrotrans_gag PF03732.17 CCH61854.1 - 5.5e-14 52.2 0.1 1.6e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 CCH61854.1 - 0.019 14.8 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Corona_NSP4_C PF16348.5 CCH61854.1 - 0.14 13.0 0.6 0.36 11.6 0.6 1.8 1 1 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus Ras PF00071.22 CCH61855.1 - 0.00027 20.6 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.6 CCH61855.1 - 0.002 18.5 0.1 0.0043 17.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCH61855.1 - 0.0021 18.0 0.1 0.054 13.4 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 CCH61855.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCH61855.1 - 0.011 16.0 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CCH61855.1 - 0.034 14.3 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CCH61855.1 - 0.048 14.2 0.0 0.093 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SurA_N_2 PF13623.6 CCH61855.1 - 0.05 13.5 0.5 0.08 12.8 0.5 1.2 1 0 0 1 1 1 0 SurA N-terminal domain TniB PF05621.11 CCH61855.1 - 0.067 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 CCH61855.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CCH61855.1 - 0.21 10.8 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 CCH61855.1 - 0.21 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB WD40 PF00400.32 CCH61856.1 - 0.035 15.0 0.0 9.4 7.3 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat RVT_2 PF07727.14 CCH61857.1 - 7.9e-84 281.1 0.0 9.2e-84 280.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 CCH61857.1 - 0.016 14.7 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NAR PF16251.5 CCH61857.1 - 0.078 13.7 0.1 2.6 8.7 0.0 2.7 2 1 1 3 3 3 0 Nucleic acid-binding domain (NAR) PH PF00169.29 CCH61858.1 - 2.2e-05 24.9 15.4 0.00039 20.9 0.3 3.3 3 2 0 3 3 3 2 PH domain SHE3 PF17078.5 CCH61859.1 - 1.2e-67 228.0 41.3 1.2e-67 228.0 41.3 1.9 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 Jnk-SapK_ap_N PF09744.9 CCH61859.1 - 0.011 16.0 20.3 0.011 16.0 20.3 3.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 CCH61859.1 - 0.21 10.5 34.3 1.1 8.1 19.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein ISG65-75 PF11727.8 CCH61859.1 - 0.25 10.6 16.8 0.1 11.8 6.5 2.5 1 1 1 2 2 2 0 Invariant surface glycoprotein TSC22 PF01166.18 CCH61859.1 - 0.52 10.7 23.7 0.58 10.5 4.2 4.8 2 1 2 4 4 4 0 TSC-22/dip/bun family DUF2935 PF11155.8 CCH61859.1 - 1.2 9.5 13.8 7.1 7.0 9.9 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) TMF_DNA_bd PF12329.8 CCH61859.1 - 7.3 6.7 29.5 0.12 12.4 10.6 3.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding HJURP_C PF12347.8 CCH61859.1 - 9.8 6.3 14.6 1.1 9.3 0.3 3.6 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat SRP54 PF00448.22 CCH61860.1 - 4e-80 268.1 2.7 5.8e-79 264.3 0.7 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CCH61860.1 - 4.3e-29 101.1 9.8 4.3e-29 101.1 9.8 4.3 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CCH61860.1 - 1.5e-15 57.1 2.4 4.6e-15 55.6 2.4 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CCH61860.1 - 6.4e-05 22.6 3.5 0.00043 19.9 1.5 2.9 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CCH61860.1 - 0.00012 22.3 0.1 0.00051 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CCH61860.1 - 0.00015 21.8 0.0 0.00041 20.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 CCH61860.1 - 0.00023 20.6 5.1 0.81 9.1 0.0 4.2 3 1 1 4 4 4 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 CCH61860.1 - 0.00069 20.0 0.1 0.00069 20.0 0.1 2.7 3 0 0 3 3 2 1 AAA domain MeaB PF03308.16 CCH61860.1 - 0.0018 17.3 0.7 0.011 14.7 0.1 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 CCH61860.1 - 0.0022 17.9 0.0 0.0069 16.3 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MipZ PF09140.11 CCH61860.1 - 0.0091 15.3 1.6 0.22 10.8 0.2 2.8 2 1 0 2 2 2 1 ATPase MipZ Zeta_toxin PF06414.12 CCH61860.1 - 0.016 14.5 0.0 0.043 13.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 CCH61860.1 - 0.022 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 CCH61860.1 - 0.022 14.5 0.2 0.075 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCH61860.1 - 0.025 15.1 0.1 0.14 12.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCH61860.1 - 0.034 14.5 0.0 0.06 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 CCH61860.1 - 0.057 13.3 0.3 0.057 13.3 0.3 3.1 3 1 0 3 3 3 0 AAA domain DDE_Tnp_1_3 PF13612.6 CCH61860.1 - 0.071 13.1 0.9 0.19 11.7 0.9 1.7 1 0 0 1 1 1 0 Transposase DDE domain ATP_bind_1 PF03029.17 CCH61860.1 - 0.087 12.6 0.2 0.087 12.6 0.2 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CCH61860.1 - 0.091 13.0 0.8 0.42 10.9 0.4 2.5 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 CCH61860.1 - 0.099 12.9 0.0 0.4 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCH61860.1 - 0.18 11.5 0.1 0.18 11.5 0.1 2.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CCH61860.1 - 0.22 11.6 2.2 0.49 10.5 0.1 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase CLP1_P PF16575.5 CCH61860.1 - 0.24 11.2 2.2 19 5.0 0.1 3.0 4 0 0 4 4 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop KTI12 PF08433.10 CCH61860.1 - 0.52 9.7 4.8 1.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA PF00004.29 CCH61860.1 - 0.52 10.7 7.7 0.69 10.3 1.2 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CCH61860.1 - 0.83 9.5 6.2 3.9 7.4 2.8 2.9 2 1 0 2 2 2 0 NTPase Aa_trans PF01490.18 CCH61861.1 - 1.2e-85 287.7 32.2 1.4e-85 287.5 32.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PBP1_TM PF14812.6 CCH61861.1 - 0.071 13.5 0.9 8 6.9 0.0 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AA_permease PF00324.21 CCH61862.1 - 4.2e-119 398.3 32.9 5.3e-119 397.9 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH61862.1 - 8.6e-19 67.7 34.7 1.1e-18 67.3 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease PI3_PI4_kinase PF00454.27 CCH61863.1 - 3.7e-52 177.6 0.4 1.3e-51 175.9 0.4 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CCH61863.1 - 7.7e-20 70.7 3.7 3.8e-19 68.5 0.2 3.6 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 CCH61863.1 - 6.6e-14 51.4 0.4 1.5e-13 50.3 0.4 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 CCH61863.1 - 0.00028 20.2 4.8 0.0011 18.3 4.7 2.0 1 1 0 1 1 1 1 FAT domain TPR_19 PF14559.6 CCH61863.1 - 0.058 13.9 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat MMM1 PF10296.9 CCH61864.1 - 1.8e-08 33.8 2.1 1.8e-08 33.8 2.1 3.1 2 1 1 3 3 3 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 CCH61864.1 - 3.9e-08 33.6 0.4 3.9e-08 33.6 0.4 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CCH61864.1 - 2.7e-05 24.6 4.0 0.00027 21.4 1.9 2.9 1 1 1 2 2 2 1 PH domain Cofilin_ADF PF00241.20 CCH61865.1 - 4.2e-27 94.4 4.4 1.3e-13 50.8 0.6 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein T4BSS_DotH_IcmK PF12293.8 CCH61865.1 - 0.0052 16.1 0.3 0.66 9.2 0.1 2.1 2 0 0 2 2 2 2 Putative outer membrane core complex of type IVb secretion COS PF18568.1 CCH61865.1 - 0.031 14.2 0.4 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 TRIM C-terminal subgroup One Signature domain FAINT PF04385.15 CCH61865.1 - 0.86 9.7 9.2 0.057 13.5 2.2 2.7 3 0 0 3 3 3 0 Domain of unknown function, DUF529 zf-RING_2 PF13639.6 CCH61866.1 - 3e-11 43.5 21.8 6.6e-10 39.2 7.7 3.0 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 CCH61866.1 - 1.7e-07 31.0 6.8 1.7e-07 31.0 6.8 3.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH61866.1 - 1.7e-07 30.9 6.9 1.7e-07 30.9 6.9 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH61866.1 - 6.7e-07 29.2 2.2 6.7e-07 29.2 2.2 4.1 4 2 2 6 6 5 1 RING-type zinc-finger zf-rbx1 PF12678.7 CCH61866.1 - 2.3e-06 27.8 6.2 2.3e-06 27.8 6.2 3.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCH61866.1 - 0.00025 21.0 2.7 0.00025 21.0 2.7 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CCH61866.1 - 0.00027 20.5 5.1 0.00027 20.5 5.1 2.9 3 1 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CCH61866.1 - 0.00028 20.6 4.8 0.00028 20.6 4.8 3.4 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CCH61866.1 - 0.0053 16.6 5.0 0.0053 16.6 5.0 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CCH61866.1 - 0.0058 16.5 7.3 0.0058 16.5 7.3 3.1 3 0 0 3 3 3 1 PHD-finger zf-C3HC4_4 PF15227.6 CCH61866.1 - 0.02 15.1 4.3 0.02 15.1 4.3 3.8 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 CCH61866.1 - 0.046 13.8 20.2 0.087 12.9 7.6 3.3 2 1 1 3 3 3 0 KIAA1045 RING finger zf-Nse PF11789.8 CCH61866.1 - 0.65 9.9 9.1 0.12 12.2 4.1 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHF5 PF03660.14 CCH61867.1 - 1.8e-43 147.0 11.4 2e-43 146.8 11.4 1.0 1 0 0 1 1 1 1 PHF5-like protein Sec7 PF01369.20 CCH61868.1 - 1.1e-25 90.4 2.5 4.4e-25 88.4 2.5 2.1 1 0 0 1 1 1 1 Sec7 domain HIM1 PF08732.10 CCH61869.1 - 4.1e-09 36.2 0.0 5.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 CCH61869.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Proteasom_Rpn13 PF04683.13 CCH61870.1 - 4.1e-20 72.1 0.0 5.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DHR-2 PF06920.13 CCH61871.1 - 7.2e-39 133.8 2.1 1.8e-38 132.5 0.6 2.3 2 1 0 2 2 2 1 Dock homology region 2 DOCK_N PF16172.5 CCH61871.1 - 1.9e-14 53.4 0.0 6.9e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 DOCK N-terminus Elf4 PF07011.11 CCH61871.1 - 0.18 11.8 1.1 0.95 9.4 0.1 2.8 2 0 0 2 2 2 0 Early Flowering 4 domain CHCH PF06747.13 CCH61872.1 - 2.7e-08 33.7 3.9 6e-08 32.6 3.9 1.6 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CCH61872.1 - 8.2e-05 22.9 2.8 0.00023 21.5 2.8 1.8 1 0 0 1 1 1 1 GCK domain MGC-24 PF05283.11 CCH61872.1 - 3.2 8.2 8.2 4.4 7.7 0.2 2.5 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Synaptobrevin PF00957.21 CCH61873.1 - 1.3e-14 53.8 1.3 2e-14 53.1 1.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CCH61873.1 - 1e-11 44.7 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUR7 PF06687.12 CCH61874.1 - 4.7e-14 52.5 15.8 7.1e-11 42.1 10.9 2.6 2 1 0 2 2 2 2 SUR7/PalI family Dynein_C PF18199.1 CCH61874.1 - 0.022 14.0 3.8 0.02 14.1 1.9 1.7 1 1 1 2 2 2 0 Dynein heavy chain C-terminal domain RNase_3_N PF18497.1 CCH61874.1 - 0.071 13.3 1.2 0.2 11.9 0.5 2.2 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain DUF4512 PF14975.6 CCH61874.1 - 0.084 13.7 0.6 5.8 7.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) ATP-cone PF03477.16 CCH61874.1 - 0.12 12.9 0.6 1.7 9.3 0.0 2.6 2 0 0 2 2 2 0 ATP cone domain Fig1 PF12351.8 CCH61874.1 - 0.17 11.8 15.0 0.41 10.5 9.3 2.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 MARVEL PF01284.23 CCH61874.1 - 8.6 6.4 16.6 4.3 7.4 10.9 3.0 2 1 1 3 3 3 0 Membrane-associating domain Rif1_N PF12231.8 CCH61875.1 - 1.9e-29 102.8 15.8 1.9e-29 102.8 15.8 2.7 2 1 1 3 3 3 1 Rap1-interacting factor 1 N terminal Carm_PH PF17888.1 CCH61875.1 - 0.26 11.7 2.8 18 5.8 0.0 3.6 3 0 0 3 3 3 0 Carmil pleckstrin homology domain SHMT PF00464.19 CCH61876.1 - 5.4e-192 637.7 0.0 6.4e-192 637.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF3287 PF11690.8 CCH61876.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) AIM5 PF17050.5 CCH61877.1 - 7.9e-06 26.6 0.0 1.1e-05 26.2 0.0 1.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria 5 Methyltransf_PK PF05891.12 CCH61878.1 - 3.6e-92 307.8 0.0 4.1e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CCH61878.1 - 3.1e-05 24.6 0.0 5.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH61878.1 - 8.3e-05 22.5 0.0 0.00017 21.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH61878.1 - 0.0081 16.8 0.0 0.022 15.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Bin3 PF06859.12 CCH61878.1 - 0.014 16.0 0.0 0.023 15.4 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) RrnaAD PF00398.20 CCH61878.1 - 0.075 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 CCH61878.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain RhoGAP PF00620.27 CCH61879.1 - 9e-20 71.0 0.0 9e-20 71.0 0.0 2.4 2 1 1 3 3 3 1 RhoGAP domain DUF1027 PF06265.11 CCH61879.1 - 0.031 14.2 1.3 0.14 12.2 1.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) FCH PF00611.23 CCH61879.1 - 5.7 7.3 9.4 3.1 8.1 1.6 3.2 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2250 PF10007.9 CCH61880.1 - 0.098 12.8 0.3 16 5.7 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) Abhydrolase_1 PF00561.20 CCH61883.1 - 1.6e-14 54.1 2.4 3.6e-14 53.0 2.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH61883.1 - 7.6e-13 48.3 0.0 1.7e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCH61883.1 - 2.1e-11 44.9 0.0 4.7e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CCH61883.1 - 0.00092 18.2 0.0 0.0019 17.2 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 CCH61883.1 - 0.0019 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CCH61883.1 - 0.0055 16.6 0.0 0.0095 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase tRNA-synt_2 PF00152.20 CCH61884.1 - 2.2e-91 306.2 0.0 2.9e-91 305.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCH61884.1 - 3.8e-11 42.8 0.3 7.1e-11 41.9 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2540 PF10802.8 CCH61884.1 - 0.04 14.0 0.3 0.069 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Ins134_P3_kin PF05770.11 CCH61884.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain tRNA_anti_2 PF13742.6 CCH61884.1 - 0.055 13.7 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Lyase_1 PF00206.20 CCH61885.1 - 2.6e-94 316.1 0.0 3.8e-94 315.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CCH61885.1 - 1e-20 74.2 0.0 2.9e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Ysc84 PF04366.12 CCH61886.1 - 1.2e-42 144.7 0.2 2.1e-42 143.9 0.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCH61886.1 - 6.7e-17 60.8 0.0 1.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH61886.1 - 1.1e-13 50.8 0.0 2.2e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH61886.1 - 9.2e-13 47.7 0.1 2.1e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.22 CCH61887.1 - 8.1e-20 70.4 16.3 4.4e-10 39.2 1.2 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CbeA_antitoxin PF06154.11 CCH61887.1 - 0.03 14.9 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A BRAP2 PF07576.12 CCH61887.1 - 0.062 13.5 0.1 0.062 13.5 0.1 4.2 4 0 0 4 4 4 0 BRCA1-associated protein 2 Nup35_RRM_2 PF14605.6 CCH61887.1 - 0.5 10.4 4.0 0.54 10.3 0.7 2.6 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Endonuc-EcoRV PF09233.11 CCH61888.1 - 0.04 13.3 0.2 0.04 13.3 0.2 1.7 2 0 0 2 2 2 0 Restriction endonuclease EcoRV CENP-X PF09415.10 CCH61888.1 - 0.62 10.4 3.1 3.4 8.0 1.7 2.5 2 1 0 2 2 2 0 CENP-S associating Centromere protein X RVT_2 PF07727.14 CCH61890.1 - 8.9e-50 169.6 0.9 1.4e-49 168.9 0.9 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5341 PF17276.2 CCH61891.1 - 1.8e-21 77.0 8.5 2.6e-21 76.5 8.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5341) Zn_clus PF00172.18 CCH61892.1 - 0.0013 18.8 15.1 0.0023 18.0 3.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Cohesin_load PF10345.9 CCH61893.1 - 4.6e-29 101.3 64.7 4.6e-28 98.0 64.7 2.7 1 1 0 1 1 1 1 Cohesin loading factor Glyco_transf_20 PF00982.21 CCH61894.1 - 1.3e-144 482.4 3.8 1.8e-144 482.0 3.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCH61894.1 - 5.3e-77 258.1 0.4 1.1e-76 257.1 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase PAP2_3 PF14378.6 CCH61896.1 - 3.8e-11 43.0 25.9 7.2e-11 42.1 7.5 2.9 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CCH61896.1 - 8.4e-07 28.8 17.6 0.00022 21.0 1.5 3.8 3 1 0 3 3 3 2 PAP2 superfamily Tetraspanin PF00335.20 CCH61896.1 - 0.61 9.8 4.5 1.2 8.8 4.5 1.5 1 0 0 1 1 1 0 Tetraspanin family Acetyltransf_1 PF00583.25 CCH61897.1 - 7.3e-18 64.9 0.0 9.6e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCH61897.1 - 3e-12 46.6 0.0 4.3e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCH61897.1 - 1.8e-05 25.1 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCH61897.1 - 0.00072 19.1 0.1 0.00081 18.9 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CCH61897.1 - 0.032 14.3 0.0 0.51 10.4 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCH61897.1 - 0.076 13.1 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCH61897.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein UCH PF00443.29 CCH61898.1 - 3.3e-61 207.0 2.1 3.3e-61 207.0 2.1 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCH61898.1 - 1.7e-22 80.4 1.6 1.7e-22 80.4 1.6 4.6 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCH61898.1 - 1.9e-05 25.1 0.1 6.9e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S10 PF00338.22 CCH61898.1 - 0.0036 17.5 0.0 0.032 14.4 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e BSD PF03909.17 CCH61899.1 - 1.6e-15 56.8 0.1 5.6e-15 55.1 0.1 2.0 1 0 0 1 1 1 1 BSD domain DUF1890 PF09001.11 CCH61899.1 - 0.44 10.9 2.6 0.73 10.2 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1890) GAT PF03127.14 CCH61899.1 - 0.59 10.5 9.6 9.6 6.6 0.0 3.6 3 1 1 4 4 4 0 GAT domain HhH-GPD PF00730.25 CCH61900.1 - 8e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EFG_II PF14492.6 CCH61900.1 - 0.2 11.8 0.9 16 5.7 0.0 2.7 3 0 0 3 3 3 0 Elongation Factor G, domain II RPAP2_Rtr1 PF04181.13 CCH61901.1 - 2e-16 60.0 2.8 2.5e-16 59.8 1.4 1.9 2 0 0 2 2 2 1 Rtr1/RPAP2 family DUF4252 PF14060.6 CCH61901.1 - 0.072 13.0 1.0 0.35 10.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Utp13 PF08625.11 CCH61901.1 - 0.32 10.9 2.9 0.31 10.9 0.6 2.1 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain EutQ PF06249.12 CCH61902.1 - 0.073 12.8 1.4 0.35 10.6 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutQ CTP_transf_like PF01467.26 CCH61902.1 - 0.21 11.7 4.8 0.068 13.4 0.6 2.1 2 1 0 2 2 2 0 Cytidylyltransferase-like Pet100 PF09803.9 CCH61903.1 - 4e-09 36.9 2.0 6.1e-09 36.3 0.7 1.8 1 1 1 2 2 2 1 Pet100 Sec34 PF04136.15 CCH61904.1 - 2.2e-38 131.5 11.4 2.2e-38 131.5 11.4 5.5 5 2 1 6 6 6 1 Sec34-like family DDE_1 PF03184.19 CCH61905.1 - 7e-67 224.4 5.7 1.9e-66 223.1 5.7 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CCH61905.1 - 2.4e-13 49.9 0.6 5.5e-13 48.7 0.6 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CCH61905.1 - 0.00042 20.0 0.1 0.0013 18.4 0.1 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Stn1 PF10451.9 CCH61906.1 - 6.2e-21 74.5 0.8 1.7e-20 73.0 0.8 1.7 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.7 CCH61906.1 - 5.3e-06 26.4 6.5 5.3e-06 26.4 6.5 2.8 1 1 1 2 2 2 1 Telomere capping C-terminal wHTH SNAD2 PF18745.1 CCH61906.1 - 0.026 14.2 0.6 0.073 12.8 0.6 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 Slu7 PF11708.8 CCH61908.1 - 4e-18 66.1 17.6 4e-18 66.1 17.6 3.3 2 2 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor PHD PF00628.29 CCH61908.1 - 0.1 12.5 0.6 0.26 11.2 0.6 1.6 1 0 0 1 1 1 0 PHD-finger zf-CCHC PF00098.23 CCH61908.1 - 0.11 12.6 1.8 0.26 11.4 1.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CCH61908.1 - 0.13 12.0 0.7 0.31 10.8 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Zn_clus PF00172.18 CCH61909.1 - 0.00031 20.8 12.0 0.00031 20.8 12.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_gyraseB PF00204.25 CCH61909.1 - 0.0077 15.7 1.9 0.13 11.8 0.1 3.1 3 0 0 3 3 3 1 DNA gyrase B GNAT_C PF18164.1 CCH61909.1 - 0.091 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 GNAT-like C-terminal domain PAS PF00989.25 CCH61909.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 PAS fold SPT2 PF08243.11 CCH61910.1 - 2.5e-28 98.8 29.7 2.5e-28 98.8 29.7 2.7 3 0 0 3 3 3 1 SPT2 chromatin protein Sigma70_r3 PF04539.16 CCH61910.1 - 0.0067 16.5 1.0 0.021 14.9 1.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 3 ABC_tran PF00005.27 CCH61911.1 - 1.6e-34 119.4 0.0 4.6e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 CCH61911.1 - 1.6e-14 53.4 5.9 4.2e-14 52.1 5.9 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 CCH61911.1 - 7.3e-10 38.7 2.1 0.0045 16.5 0.3 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCH61911.1 - 1.1e-09 38.6 8.3 0.16 11.7 0.2 4.2 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 CCH61911.1 - 2.8e-07 30.1 3.8 2.8e-07 30.1 3.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 CCH61911.1 - 1.3e-06 28.3 0.2 0.14 11.9 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 CCH61911.1 - 3.3e-06 27.6 0.1 0.011 16.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CCH61911.1 - 4e-06 26.8 0.0 0.028 14.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCH61911.1 - 9.6e-06 26.1 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCH61911.1 - 5.5e-05 23.4 0.0 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCH61911.1 - 0.00024 20.8 0.9 0.6 9.9 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CCH61911.1 - 0.00026 21.0 0.3 0.38 10.7 0.1 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4_6 PF12837.7 CCH61911.1 - 0.00078 19.4 3.1 0.00078 19.4 3.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 CCH61911.1 - 0.00088 19.8 0.3 0.00088 19.8 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_33 PF13671.6 CCH61911.1 - 0.0015 18.7 0.1 1.5 8.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain Fer4_21 PF14697.6 CCH61911.1 - 0.0021 18.2 11.8 0.0053 16.9 11.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_28 PF13521.6 CCH61911.1 - 0.0025 18.1 0.2 1.8 8.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 CCH61911.1 - 0.0033 17.2 0.3 0.29 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCH61911.1 - 0.0039 17.5 0.1 1.5 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 CCH61911.1 - 0.0043 16.3 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_10 PF13237.6 CCH61911.1 - 0.005 16.9 1.4 0.005 16.9 1.4 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 CCH61911.1 - 0.0056 16.7 0.8 0.0056 16.7 0.8 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 CCH61911.1 - 0.0079 16.3 11.4 0.017 15.3 11.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 CCH61911.1 - 0.0088 15.7 3.0 0.38 10.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 CCH61911.1 - 0.0091 15.9 1.7 0.54 10.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 CCH61911.1 - 0.011 15.4 2.1 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 CCH61911.1 - 0.014 16.4 0.3 0.014 16.4 0.3 2.8 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain AAA_18 PF13238.6 CCH61911.1 - 0.015 15.8 0.0 11 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 CCH61911.1 - 0.016 15.3 0.5 2.7 8.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CCH61911.1 - 0.02 14.9 0.0 0.81 9.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CCH61911.1 - 0.025 14.7 0.1 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CCH61911.1 - 0.029 13.9 0.2 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_17 PF13534.6 CCH61911.1 - 0.042 14.4 0.2 0.042 14.4 0.2 2.5 2 0 0 2 2 1 0 4Fe-4S dicluster domain AAA_5 PF07728.14 CCH61911.1 - 0.059 13.4 1.3 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) VirE PF05272.11 CCH61911.1 - 0.074 12.8 0.0 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 Virulence-associated protein E Septin PF00735.18 CCH61911.1 - 0.094 12.0 0.0 4.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Septin TniB PF05621.11 CCH61911.1 - 0.098 12.1 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 CCH61911.1 - 0.15 12.5 0.2 0.15 12.5 0.2 2.8 2 1 0 3 3 3 0 AAA domain Fer4_8 PF13183.6 CCH61911.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 CCH61911.1 - 0.16 10.6 0.7 0.53 8.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain DLIC PF05783.11 CCH61911.1 - 0.17 10.7 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Thymidylate_kin PF02223.17 CCH61911.1 - 0.17 11.5 0.8 30 4.2 0.1 3.3 3 0 0 3 3 3 0 Thymidylate kinase Roc PF08477.13 CCH61911.1 - 0.18 12.1 0.5 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CCH61911.1 - 0.18 10.9 0.0 6.2 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Fer4_4 PF12800.7 CCH61911.1 - 0.9 10.2 15.2 0.45 11.2 3.0 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 CCH61912.1 - 1.1e-63 215.2 0.0 3.5e-63 213.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 CCH61912.1 - 1.7e-45 154.2 5.0 1.7e-45 154.2 5.0 3.6 3 1 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 CCH61912.1 - 5.6e-28 97.2 0.4 5.6e-28 97.2 0.4 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CCH61912.1 - 3.2e-20 71.8 2.4 9e-13 47.9 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CCH61912.1 - 9.5e-20 71.0 0.0 3.1e-19 69.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH61912.1 - 2.8e-09 37.2 0.0 2.3e-07 30.9 0.0 3.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CCH61912.1 - 0.015 15.4 0.0 0.065 13.4 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain SLIDE PF09111.10 CCH61912.1 - 0.18 11.8 0.0 0.18 11.8 0.0 3.7 4 0 0 4 4 4 0 SLIDE Roughex PF06020.11 CCH61912.1 - 0.26 10.3 11.7 0.57 9.2 11.7 1.4 1 0 0 1 1 1 0 Drosophila roughex protein RRM_1 PF00076.22 CCH61913.1 - 1.1e-86 284.6 10.0 6.6e-23 80.3 0.2 4.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CCH61913.1 - 5.4e-19 68.1 1.9 4.8e-18 65.1 0.2 3.0 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CCH61913.1 - 6.1e-10 38.8 0.0 0.028 14.0 0.0 4.4 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CCH61913.1 - 1.6e-07 31.3 3.7 0.092 12.8 0.6 4.7 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.5 CCH61913.1 - 1.7e-06 28.0 0.5 0.03 14.4 0.0 4.9 4 3 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 CCH61913.1 - 0.0003 20.6 0.0 0.0088 15.9 0.0 3.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif YflT PF11181.8 CCH61913.1 - 0.0024 18.4 10.0 0.037 14.5 0.4 3.7 4 0 0 4 4 3 1 Heat induced stress protein YflT Nup35_RRM PF05172.13 CCH61913.1 - 0.0038 17.2 0.0 0.92 9.5 0.0 2.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CCH61913.1 - 0.0054 16.7 0.6 27 4.8 0.1 3.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 CCH61913.1 - 0.0078 16.0 0.0 2 8.2 0.0 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) OB_RNB PF08206.11 CCH61913.1 - 0.072 12.8 7.0 7.1 6.4 0.2 3.7 3 1 0 3 3 3 0 Ribonuclease B OB domain DbpA PF03880.15 CCH61913.1 - 0.089 12.8 0.0 71 3.5 0.0 3.5 3 0 0 3 3 3 0 DbpA RNA binding domain PNPase PF03726.14 CCH61913.1 - 1 9.9 3.7 2.2 8.9 0.0 3.1 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain NOP5NT PF08156.13 CCH61913.1 - 2.2 8.7 4.9 41 4.7 0.1 4.5 4 0 0 4 4 4 0 NOP5NT (NUC127) domain UQ_con PF00179.26 CCH61914.1 - 2.1e-47 160.3 0.0 2.4e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCH61914.1 - 0.0063 16.2 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CCH61914.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CCH61914.1 - 0.029 14.7 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain PhoLip_ATPase_C PF16212.5 CCH61915.1 - 1.9e-78 263.7 24.1 1.9e-78 263.7 24.1 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCH61915.1 - 1.6e-17 63.0 1.8 1.6e-17 63.0 1.8 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCH61915.1 - 1.9e-11 43.9 0.0 9.5e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCH61915.1 - 1.3e-08 35.4 1.9 0.0002 21.7 0.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCH61915.1 - 0.00029 20.4 0.2 0.00029 20.4 0.2 2.2 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCH61915.1 - 0.0012 18.6 0.2 0.0041 16.9 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3274 PF11678.8 CCH61916.1 - 0.026 13.8 3.8 0.059 12.6 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) DUF3439 PF11921.8 CCH61916.1 - 0.46 10.5 4.3 0.41 10.6 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FUSC-like PF12805.7 CCH61916.1 - 1.6 7.7 6.0 3 6.8 6.0 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Bac_chlorC PF02043.17 CCH61916.1 - 2.3 8.3 5.9 17 5.5 0.7 3.2 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein Methyltransf_12 PF08242.12 CCH61916.1 - 5.5 7.8 6.9 5.8 7.7 0.1 3.0 2 0 0 2 2 2 0 Methyltransferase domain JmjC PF02373.22 CCH61917.1 - 6.6e-08 33.0 0.2 3.4e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-H2C2_2 PF13465.6 CCH61917.1 - 5.3e-07 29.8 11.2 1.9e-06 28.0 6.7 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCH61917.1 - 2e-05 24.8 15.5 0.01 16.3 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CCH61917.1 - 0.0002 21.3 12.1 0.00056 19.8 4.9 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CCH61917.1 - 0.00023 21.8 15.2 0.11 13.4 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CCH61917.1 - 0.0026 17.8 3.3 0.0053 16.8 3.3 1.5 1 0 0 1 1 1 1 Zinc ribbon domain zf-C2H2_8 PF15909.5 CCH61917.1 - 0.079 13.3 2.5 0.31 11.4 2.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 CCH61917.1 - 0.31 10.7 3.6 11 5.7 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CCH61917.1 - 1 9.7 11.4 0.67 10.3 5.0 2.6 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding LIM PF00412.22 CCH61917.1 - 1.9 8.8 4.9 18 5.7 5.1 2.2 1 1 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 CCH61917.1 - 3.1 7.6 10.1 0.2 11.5 3.9 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type MutS_V PF00488.21 CCH61918.1 - 8.8e-66 221.5 0.2 2e-65 220.4 0.1 1.6 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CCH61918.1 - 1e-34 120.4 2.0 1.8e-34 119.6 0.5 2.2 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CCH61918.1 - 2.7e-32 111.3 0.0 9.9e-32 109.5 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CCH61918.1 - 7.3e-14 51.9 0.1 1.7e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CCH61918.1 - 2e-10 41.1 0.1 7.5e-10 39.2 0.1 2.0 1 1 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 CCH61918.1 - 0.049 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCH61918.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.9 3 2 0 3 3 3 0 AAA domain ADK PF00406.22 CCH61919.1 - 6.2e-45 153.0 0.0 7.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCH61919.1 - 9e-22 78.0 0.0 2.2e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CCH61919.1 - 9.4e-14 51.1 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CCH61919.1 - 1.4e-05 25.7 0.0 2.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCH61919.1 - 0.00019 21.6 0.0 0.00046 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CCH61919.1 - 0.12 12.4 0.7 0.3 11.1 0.3 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCH61919.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glutaredoxin PF00462.24 CCH61920.1 - 1.5e-19 70.0 0.2 2.1e-17 63.1 0.0 2.8 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 CCH61920.1 - 1.5e-13 50.6 0.0 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CCH61920.1 - 6.1e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CCH61920.1 - 7.9e-05 22.9 0.0 0.0024 18.1 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 CCH61920.1 - 0.0066 15.8 0.0 0.0075 15.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family MRNIP PF15749.5 CCH61920.1 - 0.0077 16.9 0.1 0.011 16.4 0.1 1.3 1 0 0 1 1 1 1 MRN-interacting protein D123 PF07065.14 CCH61920.1 - 0.026 13.7 0.5 0.038 13.2 0.5 1.2 1 0 0 1 1 1 0 D123 Thioredoxin_2 PF13098.6 CCH61920.1 - 0.038 14.4 0.2 0.23 11.9 0.0 2.3 2 2 1 3 3 3 0 Thioredoxin-like domain Myc_N PF01056.18 CCH61920.1 - 0.051 13.5 1.3 0.062 13.2 1.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Redoxin PF08534.10 CCH61920.1 - 0.086 12.6 0.0 0.29 10.9 0.0 1.7 1 1 1 2 2 2 0 Redoxin Eapp_C PF10238.9 CCH61920.1 - 0.14 12.3 0.1 0.2 11.7 0.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein FAM176 PF14851.6 CCH61920.1 - 0.18 11.5 2.3 0.29 10.8 2.3 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CCH61920.1 - 1.5 8.0 4.6 2.3 7.5 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein Methyltransf_25 PF13649.6 CCH61921.1 - 2.3e-09 37.8 0.0 3.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH61921.1 - 3.2e-09 37.3 0.0 4.9e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH61921.1 - 1.7e-08 35.1 0.0 3.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH61921.1 - 8.3e-08 32.2 0.2 1.5e-07 31.3 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH61921.1 - 1.5e-05 24.9 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCH61921.1 - 0.00088 18.7 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family BNR_6 PF15899.5 CCH61921.1 - 0.058 13.5 0.0 0.27 11.4 0.0 2.2 1 0 0 1 1 1 0 BNR-Asp box repeat MTS PF05175.14 CCH61921.1 - 0.082 12.4 0.0 0.43 10.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain 14-3-3 PF00244.20 CCH61922.1 - 9.3e-105 349.0 5.8 1.1e-104 348.8 5.8 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CCH61922.1 - 0.0011 18.9 0.2 0.0033 17.4 0.2 1.8 1 0 0 1 1 1 1 Flagellar protein FlaF TPR_12 PF13424.6 CCH61922.1 - 0.033 14.5 0.4 3.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PhoU_div PF01865.16 CCH61922.1 - 0.039 13.3 1.1 0.35 10.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF47 COPI_assoc PF08507.10 CCH61923.1 - 3.7e-28 98.2 7.5 4.5e-28 97.9 7.5 1.1 1 0 0 1 1 1 1 COPI associated protein E1_dh PF00676.20 CCH61924.1 - 3.7e-120 400.4 0.2 6.5e-120 399.6 0.0 1.4 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CCH61924.1 - 0.0042 16.3 0.4 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase ABC_trans_N PF14510.6 CCH61924.1 - 0.16 12.6 0.0 0.46 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC-transporter N-terminal KRTAP7 PF15034.6 CCH61924.1 - 0.26 12.3 5.6 0.69 10.9 0.2 3.1 2 2 1 3 3 3 0 KRTAP type 7 family Serglycin PF04360.12 CCH61925.1 - 0.031 14.2 6.4 0.066 13.2 6.4 1.5 1 0 0 1 1 1 0 Serglycin zf-RING_2 PF13639.6 CCH61925.1 - 6.6 7.2 9.4 0.59 10.5 2.8 2.4 2 0 0 2 2 2 0 Ring finger domain BUD22 PF09073.10 CCH61926.1 - 3e-63 214.7 53.6 2.1e-60 205.3 53.6 2.9 1 1 0 1 1 1 1 BUD22 Pre-PUA PF17832.1 CCH61926.1 - 0.11 13.2 9.1 4 8.2 0.1 4.0 3 0 0 3 3 3 0 Pre-PUA-like domain Bcr-Abl_Oligo PF09036.10 CCH61927.1 - 0.19 11.8 1.6 1.4 8.9 0.9 2.6 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Fez1 PF06818.15 CCH61927.1 - 1.7 9.1 22.0 3.8 7.9 7.8 2.4 1 1 2 3 3 3 0 Fez1 Lzipper-MIP1 PF14389.6 CCH61927.1 - 2.1 8.7 12.2 24 5.3 2.3 4.3 3 3 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1619 PF07773.11 CCH61927.1 - 2.5 8.0 11.6 0.13 12.2 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1619) DUF2347 PF09804.9 CCH61928.1 - 6.7e-71 239.2 0.8 9.5e-71 238.7 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 CCH61928.1 - 1.1e-10 40.8 0.3 5.7e-08 31.9 0.1 2.7 1 1 0 2 2 2 1 Transport protein Avl9 DUF4484 PF14831.6 CCH61928.1 - 1.9e-07 31.3 0.1 3.3e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 CCH61928.1 - 1.5e-05 25.0 0.1 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis dsrm PF00035.26 CCH61929.1 - 5e-07 30.3 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CCH61929.1 - 0.015 15.9 0.0 0.041 14.5 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain Tim17 PF02466.19 CCH61930.1 - 5.2e-25 88.0 3.9 7.2e-25 87.5 3.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 CCH61930.1 - 0.038 14.1 6.7 0.91 9.7 0.1 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Peptidase_S8 PF00082.22 CCH61931.1 - 1.5e-16 60.6 58.1 1e-14 54.6 57.7 3.6 1 1 0 1 1 1 1 Subtilase family DUF3139 PF11337.8 CCH61931.1 - 3.4 8.4 14.4 0.1 13.3 4.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) WBS_methylT PF12589.8 CCH61932.1 - 2.6e-12 47.3 4.1 2.6e-12 47.3 4.1 1.7 2 0 0 2 2 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CCH61932.1 - 7.9e-12 45.7 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCH61932.1 - 3.2e-10 40.6 0.0 9.4e-10 39.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCH61932.1 - 3.5e-06 27.0 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCH61932.1 - 4.1e-06 27.5 0.1 4.3e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CCH61932.1 - 0.00035 20.4 0.0 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CCH61932.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH61932.1 - 0.0032 16.8 0.0 0.019 14.3 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 CCH61932.1 - 0.0041 17.5 0.0 0.0083 16.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.12 CCH61932.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.18 CCH61932.1 - 0.019 14.7 0.1 0.4 10.4 0.0 2.3 2 1 0 2 2 2 0 DNA methylase PrmA PF06325.13 CCH61932.1 - 0.034 13.6 0.1 0.085 12.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 CCH61932.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MBOAT PF03062.19 CCH61933.1 - 9.4e-74 248.8 40.2 1.3e-73 248.3 40.2 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CCH61933.1 - 0.00021 21.5 6.2 0.00065 19.9 6.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Bacteriocin_IIi PF11758.8 CCH61933.1 - 0.11 12.4 0.6 0.34 10.8 0.3 2.0 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin Peptidase_M76 PF09768.9 CCH61934.1 - 1.2e-70 236.7 0.9 1.7e-70 236.2 0.9 1.2 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 CCH61934.1 - 0.034 14.0 0.3 0.066 13.1 0.3 1.7 1 1 0 1 1 1 0 SprT-like family Ank_5 PF13857.6 CCH61935.1 - 1.9e-18 66.3 0.7 9.1e-13 48.2 0.6 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH61935.1 - 5.6e-13 49.1 2.8 2.1e-07 31.4 0.4 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCH61935.1 - 2.9e-12 47.0 0.5 9.3e-12 45.4 0.4 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCH61935.1 - 1.1e-08 34.6 0.6 1.7e-05 24.8 0.2 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 CCH61935.1 - 3.3e-08 33.6 1.3 6.5e-05 23.2 0.6 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF1682 PF07946.14 CCH61936.1 - 7.6e-72 242.2 8.4 9.2e-72 242.0 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Drc1-Sld2 PF11719.8 CCH61936.1 - 0.00057 19.6 3.2 0.00069 19.3 3.2 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein GCD14 PF08704.10 CCH61936.1 - 0.13 11.9 5.1 0.25 11.0 5.1 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FlaC_arch PF05377.11 CCH61936.1 - 0.26 11.7 0.1 0.26 11.7 0.1 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_L9_N PF01281.19 CCH61937.1 - 0.0038 16.8 0.1 0.0075 15.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Thr_synth_N PF14821.6 CCH61938.1 - 2.1e-26 91.9 0.0 7.5e-26 90.1 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 CCH61938.1 - 1.6e-13 50.8 0.0 3.7e-13 49.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.9 CCH61939.1 - 1.3e-37 127.7 1.0 1.3e-37 127.7 1.0 3.0 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Forkhead PF00250.18 CCH61940.1 - 2.6e-33 114.1 0.6 2.6e-33 114.1 0.6 3.0 3 0 0 3 3 3 1 Forkhead domain ANAPC4_WD40 PF12894.7 CCH61941.1 - 1.3e-06 28.6 0.0 0.0015 18.8 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH61941.1 - 0.00042 21.1 2.4 4.4 8.3 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat HMA PF00403.26 CCH61941.1 - 0.17 12.4 0.7 2.6 8.6 0.1 3.1 2 0 0 2 2 2 0 Heavy-metal-associated domain Pro_isomerase PF00160.21 CCH61942.1 - 4.2e-18 66.1 0.0 6.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DMT_6 PF04342.12 CCH61942.1 - 0.12 12.6 0.4 2.5 8.4 0.1 2.4 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) cobW PF02492.19 CCH61943.1 - 4.4e-44 150.2 0.1 7e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CCH61943.1 - 0.00062 19.5 0.1 0.0023 17.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCH61943.1 - 0.001 19.6 0.3 0.006 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain CobW_C PF07683.14 CCH61943.1 - 0.0041 17.0 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 CCH61943.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 CCH61943.1 - 0.014 14.7 0.1 0.033 13.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 CCH61943.1 - 0.02 14.8 1.6 0.79 9.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_21 PF13304.6 CCH61943.1 - 0.028 14.2 2.3 0.041 13.7 0.1 2.2 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CCH61943.1 - 0.029 14.5 0.0 0.093 12.8 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CCH61943.1 - 0.037 14.6 0.1 0.13 12.8 0.1 2.0 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CCH61943.1 - 0.067 13.2 0.5 0.38 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 CCH61943.1 - 0.074 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CCH61943.1 - 0.086 11.9 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CCH61943.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CCH61943.1 - 0.19 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CCH61943.1 - 0.23 11.4 3.5 0.24 11.3 0.2 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CCH61943.1 - 0.34 11.4 14.6 0.54 10.7 7.9 3.3 1 1 1 2 2 2 0 AAA domain Glyco_transf_22 PF03901.17 CCH61944.1 - 4.9e-24 85.3 16.7 6.6e-24 84.9 16.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Img2 PF05046.14 CCH61945.1 - 6.9e-24 84.0 0.2 1e-23 83.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 CCH61945.1 - 0.047 14.2 1.0 0.69 10.5 1.0 2.2 1 1 0 1 1 1 0 Translation initiation factor SUI1 WD40 PF00400.32 CCH61946.1 - 6.1e-60 197.8 36.3 7.6e-11 42.4 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH61946.1 - 1e-17 64.2 7.4 0.00033 20.9 0.0 5.6 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CCH61946.1 - 1.2e-09 38.5 0.0 2.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CCH61946.1 - 1e-07 31.0 10.8 0.032 12.9 0.1 5.7 3 3 2 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CCH61946.1 - 1.3e-07 31.7 0.1 0.0013 18.6 0.0 3.1 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCH61946.1 - 2.2e-05 23.6 0.2 1 8.2 0.0 4.1 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CCH61946.1 - 0.00062 18.6 0.9 0.14 10.9 0.3 3.3 2 1 0 2 2 2 1 Nup133 N terminal like Nbas_N PF15492.6 CCH61946.1 - 0.0027 17.1 2.2 0.59 9.4 0.1 3.3 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 CCH61946.1 - 0.038 12.3 0.1 2 6.7 0.0 2.8 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CCH61946.1 - 0.07 11.6 0.1 0.41 9.1 0.1 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain ubiquitin PF00240.23 CCH61947.1 - 2.7e-06 27.0 0.1 3.3e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCH61947.1 - 0.089 12.6 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glucosamine_iso PF01182.20 CCH61948.1 - 7.5e-54 183.0 0.0 1.3e-53 182.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Macoilin PF09726.9 CCH61948.1 - 0.16 10.5 8.3 0.19 10.2 8.3 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 CCH61948.1 - 4.5 5.9 4.9 6 5.5 4.9 1.1 1 0 0 1 1 1 0 Presenilin DUF3215 PF11503.8 CCH61949.1 - 1.2e-09 37.9 0.8 3e-09 36.6 0.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3215) GutM PF06923.11 CCH61949.1 - 0.078 13.1 0.2 0.14 12.2 0.2 1.5 1 1 0 1 1 1 0 Glucitol operon activator protein (GutM) PAT1 PF09770.9 CCH61950.1 - 9.1e-89 298.8 88.7 1.7e-80 271.5 87.8 4.8 2 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.14 CCH61951.1 - 2.3e-87 292.7 4.4 2.9e-87 292.3 4.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ribosom_S12_S23 PF00164.25 CCH61952.1 - 1.9e-33 114.5 0.4 2.7e-33 114.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.21 CCH61953.1 - 1.8e-23 82.2 0.0 2.2e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_M60_C PF18630.1 CCH61953.1 - 0.063 13.4 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase M60 C-terminal domain DEAD PF00270.29 CCH61954.1 - 1.2e-41 142.4 0.4 1.2e-41 142.4 0.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH61954.1 - 2e-21 76.4 0.8 2e-21 76.4 0.8 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH61954.1 - 3.2e-09 37.0 0.1 3.2e-09 37.0 0.1 3.4 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CCH61954.1 - 0.0048 16.9 0.0 0.35 10.8 0.0 2.7 1 1 0 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.6 CCH61954.1 - 0.27 11.5 2.2 1.4 9.2 2.2 2.2 1 1 0 1 1 1 0 AAA domain NESP55 PF06390.12 CCH61954.1 - 9.3 5.8 11.4 15 5.1 11.4 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Med12 PF09497.10 CCH61955.1 - 3.5e-22 78.4 0.5 1e-21 77.0 0.2 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Trm112p PF03966.16 CCH61956.1 - 9.9e-20 70.9 0.1 1.2e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-CCHC_6 PF15288.6 CCH61956.1 - 0.089 12.6 1.7 2 8.3 0.5 2.3 2 0 0 2 2 2 0 Zinc knuckle WD40 PF00400.32 CCH61957.1 - 5.2e-50 166.3 11.5 1.6e-08 35.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CCH61957.1 - 6.6e-25 87.2 14.3 6.6e-25 87.2 14.3 2.5 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CCH61957.1 - 1.7e-16 60.3 0.0 3e-05 24.3 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCH61957.1 - 1.4e-06 27.9 0.3 1.5 8.0 0.0 4.8 2 1 2 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 CCH61957.1 - 0.0003 19.9 0.0 1.3 7.9 0.0 3.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CCH61957.1 - 0.098 12.6 0.0 52 4.0 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MDD_C PF18376.1 CCH61958.1 - 1.9e-65 220.1 0.0 2.6e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CCH61958.1 - 2.2e-07 31.0 2.4 6.6e-07 29.5 2.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Thioredoxin PF00085.20 CCH61959.1 - 1.6e-26 92.3 0.2 2.5e-26 91.7 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CCH61959.1 - 3.2e-07 30.6 1.3 1.9e-05 24.9 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CCH61959.1 - 6.5e-06 26.6 0.2 1.8e-05 25.1 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CCH61959.1 - 2.9e-05 23.6 0.4 5.7e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CCH61959.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 CCH61959.1 - 0.00034 20.4 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CCH61959.1 - 0.0027 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CCH61959.1 - 0.0042 17.1 0.4 0.011 15.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin domain Redoxin PF08534.10 CCH61959.1 - 0.0066 16.2 0.3 0.02 14.6 0.3 1.8 1 1 0 1 1 1 1 Redoxin TrbC_Ftype PF09673.10 CCH61959.1 - 0.037 14.1 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein DSBA PF01323.20 CCH61959.1 - 0.041 13.6 0.3 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CCH61959.1 - 0.041 14.0 1.2 0.61 10.2 0.2 2.3 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 CCH61959.1 - 0.08 13.2 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 Glutaredoxin KaiB PF07689.12 CCH61959.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 KaiB domain MdcG PF10620.9 CCH61960.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG FBD PF08387.10 CCH61960.1 - 0.1 12.5 0.3 4.1 7.4 0.0 2.3 2 0 0 2 2 2 0 FBD PilO PF04350.13 CCH61960.1 - 0.11 12.6 6.4 0.16 12.1 6.4 1.3 1 1 0 1 1 1 0 Pilus assembly protein, PilO DUF4446 PF14584.6 CCH61960.1 - 0.19 11.7 3.1 0.3 11.1 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) YabA PF06156.13 CCH61960.1 - 4.9 7.8 9.9 1 10.1 5.7 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Flavodoxin_2 PF02525.17 CCH61961.1 - 2.6e-43 148.0 0.1 2.9e-43 147.9 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCH61961.1 - 2.2e-11 43.7 0.0 5.7e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase DUF3589 PF12141.8 CCH61962.1 - 7.5e-55 186.4 14.3 1e-38 133.2 0.0 2.7 1 1 1 2 2 2 2 Beta-mannosyltransferases RhoGAP PF00620.27 CCH61963.1 - 8.9e-34 116.5 2.2 4.1e-32 111.1 0.2 2.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CCH61963.1 - 6e-23 80.8 54.2 5.9e-09 36.0 7.8 4.6 4 0 0 4 4 4 4 LIM domain Mut7-C PF01927.16 CCH61963.1 - 0.0089 16.1 1.1 0.0089 16.1 1.1 2.7 2 0 0 2 2 2 1 Mut7-C RNAse domain DUF1487 PF07368.11 CCH61963.1 - 0.084 12.3 4.2 0.028 13.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Siva PF05458.12 CCH61963.1 - 0.26 10.9 4.2 0.78 9.4 4.2 1.8 1 0 0 1 1 1 0 Cd27 binding protein (Siva) G6PD_C PF02781.16 CCH61964.1 - 3.6e-108 361.1 0.0 4.9e-108 360.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCH61964.1 - 1.6e-57 195.0 0.0 2.6e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Globin PF00042.22 CCH61965.1 - 8.4e-05 23.1 0.0 0.00034 21.1 0.0 2.1 1 1 0 1 1 1 1 Globin PDZ_5 PF17817.1 CCH61966.1 - 0.046 14.0 0.3 0.046 14.0 0.3 3.1 3 0 0 3 3 3 0 PDZ domain CRAL_TRIO PF00650.20 CCH61967.1 - 1.6e-39 135.2 0.0 2.6e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH61967.1 - 6.5e-18 64.7 0.2 1.6e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.31 CCH61968.1 - 1.2e-23 83.0 5.7 1.6e-23 82.6 2.2 3.1 3 0 0 3 3 3 1 DnaJ domain zf-C2H2 PF00096.26 CCH61968.1 - 2.4e-07 30.8 4.5 0.00052 20.3 0.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH61968.1 - 1.7e-06 28.4 1.5 0.0023 18.6 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCH61968.1 - 2.4e-06 27.7 0.9 8.6e-06 26.0 0.9 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCH61968.1 - 5.3e-06 26.6 1.5 5.3e-06 26.6 1.5 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCH61968.1 - 1.6e-05 24.8 0.7 6e-05 22.9 0.7 2.1 1 1 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CCH61968.1 - 0.0018 18.5 11.2 0.031 14.6 4.9 3.2 3 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 CCH61968.1 - 0.0038 17.5 0.8 0.0038 17.5 0.8 3.2 3 1 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) Gal4_dimer PF03902.13 CCH61968.1 - 0.022 14.9 0.4 0.076 13.2 0.4 1.9 1 0 0 1 1 1 0 Gal4-like dimerisation domain Nrap_D5 PF17406.2 CCH61968.1 - 0.12 12.1 0.7 0.35 10.6 0.7 1.8 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 DASH_Dad3 PF08656.10 CCH61968.1 - 2 8.6 5.9 32 4.7 0.2 3.8 3 1 0 3 3 3 0 DASH complex subunit Dad3 SID PF11778.8 CCH61969.1 - 4e-44 150.0 6.8 4e-44 150.0 6.8 3.5 3 1 1 4 4 4 1 Septation initiation Peptidase_C54 PF03416.19 CCH61970.1 - 5.1e-84 282.0 0.0 7.4e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 CCH61971.1 - 2.8e-83 278.2 0.0 3.1e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF4030 PF13222.6 CCH61971.1 - 0.0021 18.2 0.1 0.0097 16.1 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4030) B_solenoid_dext PF18841.1 CCH61972.1 - 0.43 10.9 1.6 0.75 10.2 0.3 2.1 2 0 0 2 2 2 0 Beta solenoid repeat from Dextranase POP1 PF06978.11 CCH61973.1 - 3.6e-72 242.7 12.3 3.6e-72 242.7 12.3 2.5 3 1 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CCH61973.1 - 3.4e-35 120.3 1.1 8.4e-35 119.0 1.1 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain Adenylsucc_synt PF00709.21 CCH61974.1 - 3.5e-176 586.2 0.0 4e-176 586.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF713 PF05218.14 CCH61974.1 - 0.12 12.1 0.1 4.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) DUF2507 PF10702.9 CCH61975.1 - 0.046 13.6 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) IATP PF04568.12 CCH61975.1 - 3 8.3 10.0 0.076 13.4 2.5 2.2 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Glyco_transf_22 PF03901.17 CCH61976.1 - 5.3e-85 286.2 39.0 6.7e-85 285.8 39.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Hydrolase_6 PF13344.6 CCH61977.1 - 1.2e-30 105.6 0.0 7e-30 103.1 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCH61977.1 - 1.3e-14 54.0 0.0 2.5e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CCH61977.1 - 2.3e-14 54.2 0.0 3.4e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCH61977.1 - 2.7e-06 27.6 0.5 0.017 15.2 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CCH61977.1 - 0.023 14.3 0.4 0.046 13.3 0.1 1.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.10 CCH61977.1 - 0.18 11.4 0.0 1.4 8.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase MgsA_C PF12002.8 CCH61978.1 - 8.5e-51 172.2 0.0 2.5e-50 170.7 0.0 1.8 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CCH61978.1 - 1.7e-18 66.7 5.2 7e-16 58.3 5.2 2.9 1 1 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CCH61978.1 - 3.7e-15 56.5 0.1 3.7e-15 56.5 0.1 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCH61978.1 - 3.4e-12 46.4 0.0 7.7e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CCH61978.1 - 9.7e-09 35.4 0.0 9.7e-09 35.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCH61978.1 - 1.1e-06 29.1 0.1 0.0011 19.3 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CCH61978.1 - 2.8e-06 27.4 1.3 1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CCH61978.1 - 1.1e-05 25.2 0.0 7.3e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 CCH61978.1 - 1.2e-05 25.6 0.6 0.0017 18.6 0.6 2.8 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCH61978.1 - 8.2e-05 22.1 0.2 0.11 11.9 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCH61978.1 - 0.0001 22.6 0.3 0.26 11.6 0.1 2.6 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCH61978.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 CCH61978.1 - 0.00038 19.7 0.0 0.001 18.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 CCH61978.1 - 0.004 16.9 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CCH61978.1 - 0.0044 17.0 0.0 0.0044 17.0 0.0 2.9 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 CCH61978.1 - 0.0056 16.1 0.2 0.046 13.1 0.2 2.2 1 1 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 CCH61978.1 - 0.02 15.1 0.1 0.064 13.5 0.1 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 CCH61978.1 - 0.02 14.6 0.0 0.081 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH61978.1 - 0.022 15.3 3.2 0.06 13.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain Sigma54_activ_2 PF14532.6 CCH61978.1 - 0.025 14.7 0.0 0.069 13.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CCH61978.1 - 0.029 14.7 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CCH61978.1 - 0.086 12.3 0.0 0.086 12.3 0.0 2.0 3 0 0 3 3 2 0 P-loop containing dynein motor region NACHT PF05729.12 CCH61978.1 - 0.12 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain DUF3987 PF13148.6 CCH61978.1 - 4.8 6.1 5.3 27 3.6 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Hpt PF01627.23 CCH61979.1 - 8.2e-12 45.2 0.0 1.5e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Hpt domain DinB PF05163.12 CCH61979.1 - 0.028 14.3 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 DinB family DUF1729 PF08354.10 CCH61979.1 - 0.056 12.3 0.0 0.064 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) Metallophos PF00149.28 CCH61980.1 - 1.7e-11 45.0 3.8 3.4e-11 44.0 3.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCH61980.1 - 2.2e-05 24.7 0.0 4.8e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CCH61980.1 - 0.0063 15.9 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily BAH PF01426.18 CCH61980.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.6 1 1 0 1 1 1 0 BAH domain LIM_bind PF01803.16 CCH61981.1 - 1.4e-50 172.1 8.8 1.4e-50 172.1 8.8 4.2 3 1 0 3 3 3 1 LIM-domain binding protein TraD_N PF12615.8 CCH61981.1 - 0.021 15.6 1.0 0.084 13.6 0.1 2.4 2 0 0 2 2 2 0 F sex factor protein N terminal DUF4407 PF14362.6 CCH61981.1 - 0.1 11.9 6.6 0.28 10.5 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VID27_N PF17748.1 CCH61982.1 - 5e-34 117.6 2.7 7.3e-34 117.1 2.7 1.2 1 0 0 1 1 1 1 VID27 N-terminal region Ost4 PF10215.9 CCH61983.1 - 1.7e-16 59.7 3.7 1.9e-16 59.6 3.7 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase FUSC_2 PF13515.6 CCH61984.1 - 0.00024 21.2 11.7 0.00024 21.2 11.7 2.8 2 1 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CCH61984.1 - 0.00076 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 CCH61984.1 - 8 5.4 35.6 0.012 14.7 3.6 4.0 2 2 1 4 4 4 0 Putative ER transporter, 6TM, N-terminal Rick_17kDa_Anti PF05433.15 CCH61985.1 - 1.5e-08 34.4 8.3 4.1e-08 32.9 8.3 1.8 1 0 0 1 1 1 1 Glycine zipper 2TM domain RTX PF02382.15 CCH61985.1 - 0.08 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein Phage_holin_2_4 PF16082.5 CCH61985.1 - 0.17 11.7 3.2 0.46 10.3 3.2 1.8 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Gly-zipper_Omp PF13488.6 CCH61985.1 - 1 9.4 13.0 3 7.9 12.5 2.1 1 1 1 2 2 2 0 Glycine zipper Spt20 PF12090.8 CCH61985.1 - 2.4 7.7 11.1 1.5 8.3 3.7 2.0 2 0 0 2 2 2 0 Spt20 family DUF3824 PF12868.7 CCH61985.1 - 2.5 8.7 14.0 0.048 14.3 6.7 1.8 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) RIO1 PF01163.22 CCH61986.1 - 3.7e-38 131.0 2.6 1.2e-34 119.5 2.6 2.3 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CCH61986.1 - 5.5e-30 103.4 0.1 1.6e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CCH61986.1 - 0.00015 21.7 0.0 0.58 10.0 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family NOA36 PF06524.12 CCH61986.1 - 1.1 8.5 14.7 2.5 7.3 14.7 1.5 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 CCH61986.1 - 1.6 8.1 17.1 9.7 5.5 0.0 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CCH61986.1 - 7.6 4.6 15.4 3.3 5.8 10.8 2.0 2 0 0 2 2 2 0 Nop14-like family PH_18 PF18469.1 CCH61987.1 - 3.8e-45 153.3 8.4 3.8e-45 153.3 8.4 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 CCH61987.1 - 4e-26 91.3 0.4 4e-26 91.3 0.4 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 CCH61987.1 - 6.2e-09 35.5 0.0 2.1e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain CDC45 PF02724.14 CCH61987.1 - 4 5.6 14.9 6.1 5.0 14.9 1.3 1 0 0 1 1 1 0 CDC45-like protein ArfGap PF01412.18 CCH61988.1 - 8.6e-32 109.7 1.3 2.1e-31 108.4 0.0 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf YjeF_N PF03853.15 CCH61989.1 - 2e-35 122.2 0.0 2.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Septin PF00735.18 CCH61991.1 - 1.9e-63 214.4 5.1 7.7e-57 192.7 2.9 2.3 2 0 0 2 2 2 2 Septin AAA_33 PF13671.6 CCH61991.1 - 0.00065 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCH61991.1 - 0.00086 19.6 0.0 0.0031 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH61991.1 - 0.00088 19.8 0.1 0.013 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCH61991.1 - 0.0011 18.5 2.1 0.0027 17.2 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCH61991.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 CCH61991.1 - 0.045 13.1 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family RNA_helicase PF00910.22 CCH61991.1 - 0.051 14.0 0.0 0.2 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase DUF4611 PF15387.6 CCH61991.1 - 0.065 13.5 3.4 0.2 11.9 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AAA_28 PF13521.6 CCH61991.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCH61991.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF5097 PF17020.5 CCH61991.1 - 0.18 12.1 1.4 1.5 9.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5097) DAGK_cat PF00781.24 CCH61992.1 - 5.2e-24 84.3 0.0 9.5e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SnAC PF14619.6 CCH61992.1 - 0.49 11.0 8.5 0.9 10.2 5.1 2.7 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex TMA7 PF09072.10 CCH61993.1 - 1.6e-23 83.3 18.7 1.7e-23 83.2 18.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 tRNA-synt_1c PF00749.21 CCH61994.1 - 2.6e-115 384.6 0.0 3.7e-115 384.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CCH61994.1 - 1.7e-50 171.2 0.8 2.7e-50 170.5 0.8 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CCH61994.1 - 2.5e-33 115.4 0.0 1.5e-31 109.6 0.0 2.5 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CCH61994.1 - 3.6e-14 53.5 4.5 9.4e-14 52.1 4.5 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Red1 PF07964.11 CCH61995.1 - 6.2e-80 269.4 66.0 2.1e-46 158.6 47.6 2.1 1 1 1 2 2 2 2 Rec10 / Red1 Ribosomal_S28e PF01200.18 CCH61996.1 - 1.6e-32 111.2 2.0 1.8e-32 111.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 CCH61996.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region PIN_4 PF13638.6 CCH61997.1 - 4.3e-30 104.7 0.4 4.3e-30 104.7 0.4 2.0 2 0 0 2 2 2 1 PIN domain Zn_clus PF00172.18 CCH61998.1 - 4.6e-08 33.0 11.0 4.6e-08 33.0 11.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP1_TIP1 PF00660.17 CCH61999.1 - 4.3e-37 126.2 0.8 4.3e-37 126.2 0.8 2.0 2 0 0 2 2 2 1 Seripauperin and TIP1 family Tcp11 PF05794.13 CCH61999.1 - 0.28 10.2 2.8 0.38 9.8 2.8 1.3 1 0 0 1 1 1 0 T-complex protein 11 Zn_clus PF00172.18 CCH62000.1 - 6.3e-08 32.6 8.4 1.6e-07 31.3 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORF6N PF10543.9 CCH62000.1 - 0.063 13.5 0.2 0.17 12.1 0.2 1.7 1 0 0 1 1 1 0 ORF6N domain DUF2576 PF10845.8 CCH62000.1 - 0.084 12.5 0.1 0.26 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Zn_clus PF00172.18 CCH62001.1 - 6.3e-08 32.6 11.6 6.3e-08 32.6 11.6 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3808 PF10300.9 CCH62001.1 - 0.0028 16.5 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Longin PF13774.6 CCH62002.1 - 7.2e-19 67.6 0.2 1.2e-18 66.9 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CCH62002.1 - 7.6e-17 60.9 0.3 1.2e-16 60.3 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 CCH62002.1 - 0.0041 17.1 0.1 0.0066 16.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Lipoprotein_9 PF03180.14 CCH62002.1 - 0.023 13.8 0.6 0.071 12.2 0.1 1.8 1 1 0 2 2 2 0 NLPA lipoprotein E1-E2_ATPase PF00122.20 CCH62002.1 - 0.044 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 E1-E2 ATPase DcpS PF05652.12 CCH62003.1 - 1.6e-36 125.3 0.1 2.7e-36 124.6 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CCH62003.1 - 6.1e-28 97.6 0.8 2.2e-27 95.8 0.1 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Med4 PF10018.9 CCH62004.1 - 5.4e-33 114.3 3.8 5.4e-33 114.3 3.8 2.5 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 NAGLU_C PF12972.7 CCH62004.1 - 0.00039 20.1 1.4 0.00068 19.3 1.4 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain DUF3535 PF12054.8 CCH62004.1 - 0.025 13.8 0.2 0.025 13.8 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) MLD PF11647.8 CCH62004.1 - 0.035 14.4 1.8 0.077 13.3 0.2 2.3 2 1 1 3 3 3 0 Membrane Localization Domain HMMR_N PF15905.5 CCH62004.1 - 7.6 5.9 15.4 0.47 9.9 8.7 2.2 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Cnd1 PF12717.7 CCH62005.1 - 7e-44 149.7 10.0 2e-42 145.0 0.3 6.7 7 1 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CCH62005.1 - 2.7e-18 66.4 4.8 2.7e-18 66.4 4.8 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 CCH62005.1 - 2.6e-13 49.0 0.0 0.27 11.6 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 CCH62005.1 - 1.1e-06 29.0 0.0 0.017 15.5 0.0 3.9 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 CCH62005.1 - 0.0021 18.5 0.1 32 5.1 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat PXB PF12828.7 CCH62005.1 - 0.05 13.6 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 PX-associated fn3_2 PF16893.5 CCH62006.1 - 9.3e-39 131.5 0.2 1.9e-38 130.5 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CCH62006.1 - 9.3e-23 79.9 0.2 1.6e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CCH62006.1 - 5.7e-12 45.8 0.0 1.8e-11 44.2 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 CCH62006.1 - 0.00059 20.0 0.3 0.0028 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.7 CCH62006.1 - 0.00092 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CCH62006.1 - 0.0022 18.3 0.1 0.0086 16.5 0.1 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ATP-synt_F PF01990.17 CCH62007.1 - 1.7e-32 111.6 0.2 1.9e-32 111.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Transcrip_reg PF01709.20 CCH62008.1 - 5e-72 242.2 5.1 5.8e-72 242.0 5.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator DDE_Tnp_ISAZ013 PF07592.11 CCH62008.1 - 0.056 12.4 1.9 0.13 11.3 0.6 1.9 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain Mid2 PF04478.12 CCH62009.1 - 6e-44 149.5 4.0 6e-44 149.5 4.0 4.6 5 0 0 5 5 5 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 CCH62009.1 - 0.15 11.5 1.0 0.65 9.4 0.1 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Oxidored_FMN PF00724.20 CCH62010.1 - 4.7e-106 354.9 0.0 5.4e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RabGAP-TBC PF00566.18 CCH62011.1 - 1.6e-05 24.7 9.5 0.0073 16.0 0.2 3.1 3 1 1 4 4 4 2 Rab-GTPase-TBC domain CelTOS PF18659.1 CCH62011.1 - 0.088 13.2 0.8 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites Prp19 PF08606.11 CCH62012.1 - 8.4e-29 99.4 1.7 1.6e-28 98.5 1.7 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 CCH62012.1 - 0.0018 18.4 0.1 0.0091 16.2 0.0 2.3 2 0 0 2 2 2 1 U-box domain DUF5640 PF18692.1 CCH62012.1 - 0.4 10.8 6.4 0.7 10.0 0.1 3.9 4 1 0 4 4 4 0 Family of unknown function (DUF5640) HALZ PF02183.18 CCH62012.1 - 0.88 9.9 5.1 7 7.0 0.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ENTH PF01417.20 CCH62013.1 - 1.9e-30 105.5 2.2 3.3e-30 104.7 2.2 1.4 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 CCH62013.1 - 0.046 13.6 0.6 0.084 12.7 0.6 1.4 1 0 0 1 1 1 0 VHS domain Cullin_Nedd8 PF10557.9 CCH62013.1 - 0.12 12.4 2.5 2.5 8.2 0.9 2.5 1 1 1 2 2 2 0 Cullin protein neddylation domain ubiquitin PF00240.23 CCH62014.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 CCH62014.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCH62014.1 - 7.6e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 CCH62014.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CCH62014.1 - 1.8e-12 47.5 2.2 0.013 15.8 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCH62014.1 - 4.7e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCH62014.1 - 7.2e-10 39.4 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCH62014.1 - 2.4e-08 34.0 0.2 0.39 10.5 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 CCH62014.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 CCH62014.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 CCH62014.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 CCH62014.1 - 0.00028 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 CCH62014.1 - 0.00061 19.2 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 CCH62014.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 CCH62014.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 CCH62014.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 CCH62014.1 - 0.0077 15.7 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 CCH62014.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 CCH62014.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 CCH62014.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 CCH62014.1 - 0.083 13.0 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 CCH62014.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 CCH62014.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 CCH62014.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 CCH62014.1 - 0.46 10.1 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 CCH62014.1 - 0.53 8.9 10.5 8.3 4.9 0.4 3.9 2 1 1 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 CCH62014.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 CCH62014.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain SHR-BD PF06650.12 CCH62015.1 - 4.1e-85 285.4 6.1 9.8e-84 280.9 0.6 3.7 2 1 1 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CCH62015.1 - 2.8e-83 278.9 10.4 1.6e-79 266.6 1.3 5.1 5 0 0 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 CCH62015.1 - 5.8e-77 258.7 10.0 3.6e-76 256.1 4.7 3.5 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CCH62015.1 - 3.1e-71 238.8 7.9 9.5e-67 224.2 1.1 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CCH62015.1 - 6.1e-37 126.3 1.6 2.1e-36 124.5 0.5 2.6 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CCH62015.1 - 0.0097 16.2 0.3 0.063 13.6 0.1 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain V-SNARE_C PF12352.8 CCH62016.1 - 2.2e-15 56.7 2.7 2.2e-15 56.7 2.7 3.2 4 1 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Peptidase_M32 PF02074.15 CCH62016.1 - 0.021 13.6 6.3 0.025 13.4 6.3 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase Sec20 PF03908.13 CCH62016.1 - 0.022 14.7 3.9 0.19 11.7 0.0 2.6 2 1 1 3 3 3 0 Sec20 WXG100 PF06013.12 CCH62016.1 - 0.056 13.7 5.6 4.1 7.7 0.1 3.7 2 1 2 4 4 4 0 Proteins of 100 residues with WXG FUSC PF04632.12 CCH62016.1 - 0.28 9.7 5.5 1 7.8 5.5 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family Na_Ca_ex_C PF16494.5 CCH62016.1 - 1.2 9.6 5.2 0.31 11.5 1.5 1.8 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Syntaxin-6_N PF09177.11 CCH62016.1 - 2.2 8.9 14.6 0.31 11.6 4.5 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Gastrin PF00918.17 CCH62016.1 - 10 7.1 11.1 0.57 11.1 2.4 2.2 1 1 2 3 3 3 0 Gastrin/cholecystokinin family RRM_1 PF00076.22 CCH62017.1 - 3.7e-08 33.1 5.3 0.15 11.9 0.6 4.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADPRTs_Tse2 PF18648.1 CCH62017.1 - 0.02 14.9 1.0 0.064 13.3 0.9 1.9 1 1 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins ABC_tran PF00005.27 CCH62018.1 - 1.8e-58 196.9 0.1 9.7e-34 116.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CCH62018.1 - 4.4e-55 187.3 29.4 4.3e-38 131.5 10.1 3.8 4 0 0 4 4 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 CCH62018.1 - 2.5e-09 37.4 1.8 0.0025 17.7 0.0 3.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH62018.1 - 1.9e-08 34.0 5.2 0.013 14.9 1.8 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH62018.1 - 2.4e-07 30.4 0.8 0.0038 16.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CCH62018.1 - 2.9e-07 31.2 0.3 0.00012 22.6 0.0 4.1 5 0 0 5 5 3 2 AAA domain RsgA_GTPase PF03193.16 CCH62018.1 - 1.1e-06 28.7 0.0 0.024 14.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CCH62018.1 - 1.5e-06 28.3 0.1 0.0025 17.9 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCH62018.1 - 1.1e-05 25.7 0.1 0.25 11.6 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 CCH62018.1 - 6.5e-05 23.4 0.0 0.74 10.2 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCH62018.1 - 0.00011 22.6 0.0 1.2 9.5 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 CCH62018.1 - 0.00012 21.3 0.1 0.061 12.4 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein ATP_bind_1 PF03029.17 CCH62018.1 - 0.00033 20.5 0.4 2.6 7.8 0.0 3.8 4 0 0 4 4 4 2 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CCH62018.1 - 0.0007 19.1 0.1 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 CCH62018.1 - 0.0015 18.6 0.3 0.54 10.3 0.1 2.8 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 CCH62018.1 - 0.0047 16.7 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CCH62018.1 - 0.005 16.2 0.3 3.3 7.0 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 CCH62018.1 - 0.0051 16.9 2.9 0.4 10.7 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 CCH62018.1 - 0.0081 15.5 0.0 2 7.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 CCH62018.1 - 0.022 14.5 0.1 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CCH62018.1 - 0.024 14.8 0.1 14 6.0 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CCH62018.1 - 0.025 14.2 1.0 1.6 8.3 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 CCH62018.1 - 0.034 13.7 0.0 0.99 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CCH62018.1 - 0.036 14.0 0.3 26 4.8 0.0 3.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CCH62018.1 - 0.051 13.3 0.1 11 5.7 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF1699 PF08004.11 CCH62018.1 - 0.053 13.2 0.1 0.19 11.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) AAA_18 PF13238.6 CCH62018.1 - 0.053 14.1 0.3 21 5.7 0.0 3.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 CCH62018.1 - 0.073 13.5 0.2 36 4.8 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.6 CCH62018.1 - 0.095 12.7 0.1 35 4.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CCH62018.1 - 0.097 12.8 0.1 6.7 6.9 0.1 2.7 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 CCH62018.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activat PF00158.26 CCH62018.1 - 0.16 11.6 0.1 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.14 CCH62018.1 - 0.17 11.8 0.1 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 CCH62018.1 - 0.26 11.6 0.5 17 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AA_permease_2 PF13520.6 CCH62019.1 - 3.9e-61 207.2 48.1 5.2e-61 206.7 48.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCH62019.1 - 2.8e-14 52.6 43.4 4.7e-14 51.8 43.4 1.3 1 1 0 1 1 1 1 Amino acid permease MotB_plug PF13677.6 CCH62019.1 - 0.052 13.2 0.1 1.3 8.7 0.0 3.0 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB DPM3 PF08285.11 CCH62019.1 - 0.28 11.4 0.1 0.28 11.4 0.1 4.6 5 1 0 5 5 5 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Zn_clus PF00172.18 CCH62020.1 - 5.1e-10 39.3 12.4 9.2e-10 38.5 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxysterol_BP PF01237.18 CCH62022.1 - 2e-83 280.3 0.1 1.5e-75 254.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein PAP_central PF04928.17 CCH62023.1 - 1.3e-108 361.7 0.0 2.3e-108 360.9 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CCH62023.1 - 4.8e-54 182.6 3.2 9.7e-54 181.5 3.2 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CCH62023.1 - 6.5e-14 52.0 1.8 1.3e-13 51.0 0.0 2.5 2 1 1 3 3 3 1 Nucleotidyltransferase domain Polbeta PF18765.1 CCH62023.1 - 0.0038 17.3 0.6 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 CCH62023.1 - 0.033 14.4 0.1 0.47 10.7 0.0 2.5 1 1 0 2 2 2 0 DNA polymerase beta palm ATP-synt_DE_N PF02823.16 CCH62024.1 - 1.7e-14 53.4 0.0 2.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain S4 PF01479.25 CCH62024.1 - 0.18 11.5 0.2 0.35 10.6 0.2 1.5 1 0 0 1 1 1 0 S4 domain Trehalase PF01204.18 CCH62025.1 - 5.7e-186 619.3 0.1 9.3e-186 618.6 0.1 1.3 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CCH62025.1 - 8.1e-15 54.2 0.4 1.6e-14 53.3 0.4 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain OCRE PF17780.1 CCH62025.1 - 0.038 14.0 0.8 0.15 12.1 0.8 2.1 1 0 0 1 1 1 0 OCRE domain HEAT PF02985.22 CCH62026.1 - 5.6e-20 69.7 1.2 0.0014 18.8 0.0 8.0 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.6 CCH62026.1 - 1.8e-18 66.6 0.9 1.1e-10 41.8 0.0 6.7 5 1 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 CCH62026.1 - 2.8e-09 37.2 0.0 0.00098 19.5 0.0 6.0 5 2 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CCH62026.1 - 2.9e-07 31.0 1.1 0.089 13.4 0.0 5.4 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CCH62026.1 - 4.6e-06 26.8 7.6 0.0014 18.7 0.1 3.8 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CCH62026.1 - 0.0078 16.1 0.5 0.0078 16.1 0.5 3.8 4 1 0 4 4 4 1 Importin-beta N-terminal domain S-AdoMet_synt_M PF02772.16 CCH62027.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain SAICAR_synt PF01259.18 CCH62028.1 - 5.6e-102 340.7 0.1 6.8e-102 340.4 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase Pkinase PF00069.25 CCH62029.1 - 1.7e-52 178.4 2.7 1.4e-50 172.1 2.7 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62029.1 - 2.8e-32 112.0 0.0 8e-31 107.2 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH62029.1 - 0.0061 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCH62029.1 - 0.04 13.2 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CCH62029.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Carn_acyltransf PF00755.20 CCH62030.1 - 3.1e-202 673.4 0.3 3.5e-202 673.1 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase zf-rbx1 PF12678.7 CCH62030.1 - 1.2 9.4 2.9 0.86 9.9 0.6 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Oxysterol_BP PF01237.18 CCH62031.1 - 2.1e-137 458.0 1.2 2.1e-137 458.0 1.2 3.1 2 1 1 3 3 3 1 Oxysterol-binding protein PH PF00169.29 CCH62031.1 - 6.3e-10 39.5 0.1 2.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 CCH62031.1 - 4.3e-09 36.7 0.0 0.0066 17.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCH62031.1 - 6.3e-09 35.9 0.1 0.001 19.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCH62031.1 - 1.7e-08 34.9 0.0 0.013 16.1 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCH62031.1 - 7.2e-08 32.1 0.1 0.5 11.1 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CCH62031.1 - 1.2e-06 28.6 0.1 0.0082 16.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 CCH62031.1 - 2.2e-06 27.9 0.8 9.8e-06 25.8 0.1 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Phos_pyr_kin PF08543.12 CCH62032.1 - 1.9e-78 263.2 0.0 2.8e-78 262.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CCH62032.1 - 4.4e-54 183.5 0.2 7e-54 182.8 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CCH62032.1 - 4.7e-05 22.8 0.0 8.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1852 PF08908.11 CCH62032.1 - 0.028 13.4 0.3 0.042 12.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Glyco_transf_54 PF04666.13 CCH62032.1 - 0.059 12.2 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region zf-C2H2 PF00096.26 CCH62033.1 - 0.0015 18.9 7.2 0.24 11.9 0.3 3.2 2 1 0 2 2 2 2 Zinc finger, C2H2 type Utp13 PF08625.11 CCH62033.1 - 0.075 12.9 0.1 0.075 12.9 0.1 2.5 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain MetJ PF01340.20 CCH62033.1 - 0.43 10.6 0.1 0.43 10.6 0.1 3.2 3 0 0 3 3 3 0 Met Apo-repressor, MetJ His_Phos_1 PF00300.22 CCH62034.1 - 2.9e-31 108.7 0.0 4.8e-15 55.8 0.0 3.0 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) AFG1_ATPase PF03969.16 CCH62036.1 - 8.6e-72 242.0 0.0 4.7e-67 226.4 0.0 3.1 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CCH62036.1 - 5e-05 23.7 0.1 0.0011 19.4 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH62036.1 - 0.00014 22.1 0.0 0.00045 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CCH62036.1 - 0.00068 19.6 0.1 0.0025 17.8 0.0 2.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA PF00004.29 CCH62036.1 - 0.0013 19.2 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCH62036.1 - 0.0061 16.6 0.3 0.047 13.7 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 CCH62036.1 - 0.0072 16.3 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCH62036.1 - 0.016 15.6 0.0 0.056 13.8 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.18 CCH62036.1 - 0.048 13.5 0.9 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein DUF366 PF04017.12 CCH62036.1 - 0.064 12.7 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF366) TsaE PF02367.17 CCH62036.1 - 0.078 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CCH62036.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain IZUMO PF15005.6 CCH62036.1 - 0.24 11.9 1.0 0.98 9.9 0.0 2.4 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated ATP-synt_D PF01813.17 CCH62037.1 - 2.1e-70 236.5 5.4 2.1e-70 236.5 5.4 1.4 2 0 0 2 2 2 1 ATP synthase subunit D HtrL_YibB PF09612.10 CCH62037.1 - 0.024 14.2 1.1 0.037 13.5 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) GAS PF13851.6 CCH62037.1 - 0.2 11.0 0.1 0.2 11.0 0.1 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Glyco_tran_WbsX PF14307.6 CCH62037.1 - 0.95 8.8 3.9 0.67 9.4 1.6 1.8 1 1 1 2 2 2 0 Glycosyltransferase WbsX Laminin_II PF06009.12 CCH62037.1 - 2.4 8.2 9.5 0.74 9.8 0.1 3.1 2 2 1 3 3 3 0 Laminin Domain II Ribosomal_L6e PF01159.19 CCH62037.1 - 4.4 7.9 8.4 0.59 10.7 3.4 2.1 2 1 0 2 2 2 0 Ribosomal protein L6e TSP_NTD PF17804.1 CCH62037.1 - 6.7 6.9 11.3 4.6 7.5 5.9 2.2 2 0 0 2 2 2 0 Tail specific protease N-terminal domain eIF3g PF12353.8 CCH62038.1 - 5.8e-42 143.0 1.3 9.5e-42 142.3 1.3 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CCH62038.1 - 6.2e-14 51.6 0.1 1.1e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCH62038.1 - 0.05 13.2 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C41 PF05417.11 CCH62038.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Hepatitis E cysteine protease zf-CCCH_7 PF18586.1 CCH62038.1 - 0.35 11.2 1.7 0.63 10.4 0.4 2.0 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 DUF5341 PF17276.2 CCH62039.1 - 1e-22 81.0 5.4 1.8e-22 80.3 5.4 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5341) PAP1 PF08601.10 CCH62040.1 - 1.6e-16 61.1 0.9 1.6e-16 61.1 0.9 5.2 1 1 2 4 4 4 1 Transcription factor PAP1 bZIP_1 PF00170.21 CCH62040.1 - 2.7e-07 30.6 9.6 9.5e-07 28.8 9.6 2.0 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCH62040.1 - 0.0019 18.2 12.8 0.0019 18.2 12.8 2.4 2 1 0 2 2 2 1 Basic region leucine zipper CALCOCO1 PF07888.11 CCH62040.1 - 0.083 11.8 13.3 0.018 13.9 9.5 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4116 PF13475.6 CCH62040.1 - 0.099 12.4 0.3 0.099 12.4 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Aldo_ket_red PF00248.21 CCH62043.1 - 2.1e-62 211.0 0.1 2.3e-62 210.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Trimer_CC PF08954.11 CCH62043.1 - 0.74 9.4 2.3 2.9 7.5 0.0 2.6 2 1 0 2 2 2 0 Trimerisation motif Alg6_Alg8 PF03155.15 CCH62044.1 - 2.2e-147 492.0 25.5 2.6e-147 491.7 25.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PGM_PMM_I PF02878.16 CCH62045.1 - 2.3e-16 59.8 0.0 1.7e-08 34.3 0.0 2.5 1 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CCH62045.1 - 6.9e-11 42.2 0.1 2.9e-10 40.2 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CCH62045.1 - 0.014 16.0 0.0 0.12 13.0 0.0 2.6 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Mitochondr_Som1 PF11093.8 CCH62046.1 - 4.5e-11 42.6 0.4 5.1e-11 42.4 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Lyase_1 PF00206.20 CCH62047.1 - 1.1e-114 383.0 0.0 1.5e-114 382.6 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CCH62047.1 - 3.3e-25 88.3 0.2 1.2e-24 86.4 0.1 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.12 CCH62047.1 - 0.039 13.8 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain NPR2 PF06218.11 CCH62048.1 - 1.5e-122 409.6 4.9 1.5e-122 409.6 4.9 1.9 2 0 0 2 2 2 1 Nitrogen permease regulator 2 UPF0122 PF04297.14 CCH62048.1 - 0.032 14.5 0.4 4.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like zf-primase PF09329.11 CCH62049.1 - 9.7e-16 57.3 1.3 1.8e-15 56.5 1.3 1.5 1 0 0 1 1 1 1 Primase zinc finger DUF5088 PF17008.5 CCH62049.1 - 0.0016 18.2 0.1 0.0042 16.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5088) IreB PF06135.12 CCH62049.1 - 0.01 16.0 0.5 0.12 12.6 0.1 2.6 2 0 0 2 2 2 0 IreB regulatory phosphoprotein tRNA_anti-codon PF01336.25 CCH62049.1 - 0.035 14.1 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Nkap_C PF06047.11 CCH62049.1 - 0.052 13.7 0.5 0.052 13.7 0.5 2.2 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain SUB1_ProdP9 PF18213.1 CCH62049.1 - 0.24 11.2 5.1 0.27 11.1 1.0 3.0 3 0 0 3 3 3 0 SUB1 protease Prodomain ProdP9 Pcc1 PF09341.10 CCH62050.1 - 1.6e-19 69.8 0.0 1.8e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 Pih1_fungal_CS PF18482.1 CCH62050.1 - 0.1 13.2 0.1 1.3 9.6 0.0 2.2 1 1 1 2 2 2 0 Fungal Pih1 CS domain DNA_ligase_A_M PF01068.21 CCH62051.1 - 2.9e-51 174.0 0.0 6e-51 173.0 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCH62051.1 - 6.3e-26 91.7 2.0 1.4e-25 90.6 0.6 2.3 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 CCH62051.1 - 1.7e-23 82.8 0.8 9.2e-13 48.4 0.0 3.6 3 1 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 CCH62051.1 - 1.9e-10 41.3 0.1 4.3e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 CCH62051.1 - 2e-08 34.5 0.4 9.7e-05 22.7 0.0 3.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 CCH62051.1 - 1.2e-05 25.8 0.0 3.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 CCH62051.1 - 0.00088 19.2 0.6 0.59 9.9 0.6 2.9 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain DUF3960 PF13142.6 CCH62051.1 - 0.048 13.8 0.1 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3960) SGTA_dimer PF16546.5 CCH62052.1 - 7e-24 83.4 2.7 2e-23 81.9 2.7 1.8 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CCH62052.1 - 4.2e-18 64.3 15.0 2.5e-07 30.2 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62052.1 - 2.3e-16 58.5 13.4 3.1e-05 23.7 0.2 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62052.1 - 6e-12 45.1 13.9 0.00017 21.2 4.4 3.5 1 1 2 3 3 3 3 TPR repeat TPR_10 PF13374.6 CCH62052.1 - 6.9e-07 28.9 1.9 0.011 15.5 0.3 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH62052.1 - 7.4e-07 29.4 6.4 0.014 15.7 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62052.1 - 1.4e-06 28.0 19.3 0.0019 18.2 0.8 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCH62052.1 - 2.3e-06 28.1 6.2 0.002 18.7 1.8 2.9 2 1 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH62052.1 - 1.1e-05 25.5 9.2 0.0029 17.9 0.7 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCH62052.1 - 4.4e-05 23.2 2.5 0.7 10.1 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH62052.1 - 0.00024 21.6 3.3 1.1 10.3 0.1 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCH62052.1 - 0.0004 20.5 0.0 0.02 15.0 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 CCH62052.1 - 0.0024 18.3 0.7 0.043 14.3 0.1 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain GerD PF17898.1 CCH62052.1 - 0.0044 16.9 0.3 0.02 14.8 0.1 2.2 2 0 0 2 2 1 1 Spore germination GerD central core domain TPR_19 PF14559.6 CCH62052.1 - 0.0059 17.1 7.6 0.61 10.6 0.3 3.2 1 1 1 3 3 2 2 Tetratricopeptide repeat STI1 PF17830.1 CCH62052.1 - 0.017 15.0 12.5 0.64 10.0 1.6 2.5 1 1 1 2 2 2 0 STI1 domain Fis1_TPR_C PF14853.6 CCH62052.1 - 0.021 14.9 2.8 2.9 8.0 0.1 3.4 4 0 0 4 4 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CCH62052.1 - 0.028 15.0 6.8 1.2 9.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat LemA PF04011.12 CCH62052.1 - 0.076 12.9 0.5 0.076 12.9 0.5 1.9 2 0 0 2 2 2 0 LemA family Beta-Casp PF10996.8 CCH62052.1 - 0.091 13.1 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Beta-Casp domain TPR_20 PF14561.6 CCH62052.1 - 0.12 12.7 2.5 2.7 8.4 0.5 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CCH62052.1 - 0.26 11.4 21.9 1.5 8.9 1.0 4.9 4 2 0 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CCH62052.1 - 0.36 10.3 3.2 0.77 9.3 0.1 2.8 3 0 0 3 3 3 0 SHNi-TPR DUF5113 PF17140.4 CCH62052.1 - 0.36 10.6 4.7 8.2 6.2 0.5 2.8 1 1 1 3 3 3 0 Domain of unknown function (DUF5113) Homeodomain PF00046.29 CCH62053.1 - 2e-14 53.2 1.4 2e-14 53.2 1.4 2.2 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 CCH62053.1 - 6.4e-05 22.8 0.0 6.4e-05 22.8 0.0 2.7 4 0 0 4 4 4 1 Homeobox KN domain Put_DNA-bind_N PF06971.13 CCH62053.1 - 0.0045 17.0 0.1 1.7 8.7 0.0 2.6 2 0 0 2 2 2 2 Putative DNA-binding protein N-terminus Peptidase_A3 PF02160.15 CCH62053.1 - 0.009 15.5 1.8 0.011 15.3 0.5 1.9 1 1 0 1 1 1 1 Cauliflower mosaic virus peptidase (A3) Gifsy-2 PF13856.6 CCH62053.1 - 0.057 13.8 0.0 16 6.0 0.0 2.2 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage Homez PF11569.8 CCH62053.1 - 0.072 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Mis14 PF08641.12 CCH62053.1 - 0.11 12.8 4.3 0.54 10.6 0.1 2.4 2 1 0 2 2 2 0 Kinetochore protein Mis14 like Peptidase_S46 PF10459.9 CCH62053.1 - 0.27 9.8 4.0 0.33 9.6 4.0 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2120 PF09893.9 CCH62053.1 - 0.4 10.8 4.3 0.25 11.5 2.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) COMPASS-Shg1 PF05205.12 CCH62053.1 - 2.1 9.1 8.0 9.5 7.0 0.1 2.8 2 1 1 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 FapA PF03961.13 CCH62053.1 - 4.4 5.8 8.3 1.9 7.0 6.2 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A PIR PF00399.19 CCH62054.1 - 4.5e-41 137.5 68.6 8.1e-09 34.8 7.6 5.6 5 0 0 5 5 5 5 Yeast PIR protein repeat PP2C_2 PF13672.6 CCH62054.1 - 0.0062 16.2 9.2 0.64 9.6 2.9 3.1 1 1 1 2 2 2 2 Protein phosphatase 2C LeuA_dimer PF08502.10 CCH62054.1 - 0.59 10.0 9.3 1.6 8.6 1.5 3.0 1 1 2 3 3 3 0 LeuA allosteric (dimerisation) domain Phostensin PF13914.6 CCH62054.1 - 0.7 10.5 11.2 2.2 8.9 3.0 2.4 1 1 1 2 2 2 0 Phostensin PP1-binding and SH3-binding region TFIIA PF03153.13 CCH62054.1 - 5.7 6.8 13.9 7.2 6.5 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zn_clus PF00172.18 CCH62055.1 - 4.9e-06 26.6 8.9 1e-05 25.6 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 CCH62056.1 - 1.1e-08 35.1 14.6 2e-08 34.2 14.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3112 PF11309.8 CCH62056.1 - 0.85 9.0 5.8 3.2 7.2 5.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) GCD14 PF08704.10 CCH62056.1 - 1.3 8.7 6.3 5.4 6.6 6.3 2.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Menin PF05053.13 CCH62056.1 - 1.9 6.7 15.9 4.8 5.4 15.9 1.7 1 0 0 1 1 1 0 Menin Kelch_4 PF13418.6 CCH62057.1 - 6.2e-30 103.0 15.0 3.6e-07 30.1 0.1 7.2 6 2 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CCH62057.1 - 7.5e-30 102.6 3.5 2.3e-09 37.3 0.0 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF4110 PF13422.6 CCH62057.1 - 5.3e-26 90.5 0.6 5.3e-26 90.5 0.6 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 CCH62057.1 - 4.1e-18 65.0 11.3 0.00095 19.4 0.1 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 CCH62057.1 - 4.1e-16 58.6 0.2 0.0018 18.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CCH62057.1 - 1.6e-13 50.0 6.9 0.0067 16.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CCH62057.1 - 8.7e-12 44.5 15.2 0.0014 18.5 0.1 6.2 6 0 0 6 6 6 3 Kelch motif Flot PF15975.5 CCH62057.1 - 9.9e-05 22.5 1.5 0.00029 21.0 1.5 1.8 1 0 0 1 1 1 1 Flotillin BUD22 PF09073.10 CCH62057.1 - 0.92 8.8 31.1 1 8.6 15.8 2.4 2 0 0 2 2 2 0 BUD22 Aldo_ket_red PF00248.21 CCH62058.1 - 1.2e-64 218.3 0.0 1.5e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family REC114-like PF15165.6 CCH62058.1 - 0.021 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Focadhesin PF11229.8 CCH62058.1 - 0.028 12.7 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Focadhesin Fungal_trans_2 PF11951.8 CCH62059.1 - 1.9e-95 319.9 3.4 3.2e-95 319.2 3.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH62059.1 - 8.2e-10 38.6 14.2 1.5e-09 37.8 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spo0A_C PF08769.11 CCH62059.1 - 0.021 14.9 0.5 3.6 7.7 0.2 3.2 3 0 0 3 3 3 0 Sporulation initiation factor Spo0A C terminal DnaA_N PF11638.8 CCH62060.1 - 0.17 11.7 2.0 0.87 9.4 0.0 3.2 3 0 0 3 3 3 0 DnaA N-terminal domain AAA PF00004.29 CCH62060.1 - 0.27 11.7 1.6 0.46 10.9 0.3 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma70_ner PF04546.13 CCH62061.1 - 0.0019 18.1 2.1 0.0039 17.1 2.1 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region MULE PF10551.9 CCH62061.1 - 0.0078 16.6 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain CENP-B_dimeris PF09026.10 CCH62061.1 - 1.2 9.6 11.8 3.3 8.1 11.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L10 PF00466.20 CCH62063.1 - 7.6e-25 87.0 0.1 1.2e-24 86.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CCH62063.1 - 9.2e-22 76.8 0.0 1.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CCH62063.1 - 8.2e-18 64.8 1.6 8.2e-18 64.8 1.6 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein RNase_H2_suC PF08615.11 CCH62063.1 - 0.19 11.9 0.1 0.36 11.0 0.1 1.4 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Evr1_Alr PF04777.13 CCH62064.1 - 1.7e-30 105.4 5.4 1.7e-30 105.4 5.4 1.5 2 0 0 2 2 2 1 Erv1 / Alr family UPF0121 PF03661.13 CCH62065.1 - 1.2e-06 28.2 4.6 1.2e-06 28.2 4.6 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0121) Thg1 PF04446.12 CCH62066.1 - 2.7e-50 169.6 0.8 4e-50 169.0 0.8 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CCH62066.1 - 9.3e-38 129.1 0.5 1.7e-37 128.3 0.5 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Xpo1 PF08389.12 CCH62066.1 - 0.024 14.7 0.6 0.09 12.8 0.6 1.9 1 1 0 1 1 1 0 Exportin 1-like protein HABP4_PAI-RBP1 PF04774.15 CCH62067.1 - 0.0013 19.5 1.0 0.0015 19.4 0.7 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Mid2 PF04478.12 CCH62070.1 - 6.7e-52 175.3 2.1 6.7e-52 175.3 2.1 3.8 2 1 2 4 4 4 1 Mid2 like cell wall stress sensor TFIIA PF03153.13 CCH62070.1 - 0.015 15.4 4.9 0.023 14.7 4.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKG6 PF08693.10 CCH62070.1 - 0.026 13.9 0.1 0.026 13.9 0.1 2.6 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Ribosomal_S25 PF03297.15 CCH62072.1 - 1.9e-38 130.8 6.2 2.1e-38 130.6 6.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 CCH62072.1 - 6.3e-05 22.7 0.1 9.5e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 CCH62072.1 - 0.049 12.9 0.0 0.059 12.6 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 CCH62072.1 - 0.073 12.6 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.12 CCH62072.1 - 0.089 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain GntR PF00392.21 CCH62072.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ran_BP1 PF00638.18 CCH62073.1 - 3e-34 117.9 0.1 7.1e-34 116.7 0.1 1.7 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 CCH62073.1 - 1.7e-13 51.0 2.4 1.7e-13 51.0 2.4 3.4 2 1 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.17 CCH62074.1 - 1.6e-28 98.9 1.2 6.5e-28 97.0 0.3 2.6 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CCH62074.1 - 3.4e-20 72.6 11.1 1.5e-19 70.5 11.1 2.2 1 0 0 1 1 1 1 MIF4G domain WH2 PF02205.20 CCH62075.1 - 2.8e-08 33.3 0.7 1.1e-07 31.4 0.2 2.3 2 0 0 2 2 2 1 WH2 motif Alba PF01918.21 CCH62076.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Alba Glucan_synthase PF02364.15 CCH62077.1 - 0 1347.7 0.0 0 1347.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCH62077.1 - 7.7e-41 139.4 5.3 9.2e-40 136.0 5.3 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribosomal_L26 PF16906.5 CCH62078.1 - 3.6e-36 123.5 3.3 5.5e-36 122.9 3.3 1.3 1 1 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CCH62078.1 - 8.8e-05 22.3 1.2 0.00014 21.7 0.4 1.8 2 0 0 2 2 2 1 KOW motif 6PF2K PF01591.18 CCH62079.1 - 3.7e-48 163.8 3.7 3.7e-48 163.8 3.7 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCH62079.1 - 4.4e-13 49.4 0.0 8.2e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCH62079.1 - 0.095 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PAP2 PF01569.21 CCH62080.1 - 7.9e-20 71.0 0.4 7.9e-20 71.0 0.4 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 CCH62080.1 - 0.0031 17.7 0.0 0.03 14.5 0.0 2.1 2 0 0 2 2 2 1 Divergent PAP2 family HEAT_EZ PF13513.6 CCH62081.1 - 1.7e-13 50.8 8.0 4.1e-09 36.7 0.0 7.6 8 1 0 8 8 8 1 HEAT-like repeat HEAT PF02985.22 CCH62081.1 - 6.2e-12 44.7 16.1 0.0002 21.3 0.1 10.0 10 0 0 10 10 10 2 HEAT repeat IBN_N PF03810.19 CCH62081.1 - 2e-10 40.4 10.6 8.3e-09 35.2 1.7 4.8 4 1 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 CCH62081.1 - 7.2e-09 35.9 0.8 0.0064 16.9 0.0 6.5 3 2 5 8 8 8 2 HEAT repeats Arm PF00514.23 CCH62081.1 - 4.7e-05 23.3 1.5 0.0054 16.7 0.0 4.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 CCH62081.1 - 0.0019 17.8 0.1 0.034 13.7 0.0 2.7 1 1 0 2 2 2 1 Tti2 family RIX1 PF08167.12 CCH62081.1 - 0.0032 17.3 3.3 0.2 11.4 0.6 4.2 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 CCH62081.1 - 0.0042 16.7 7.9 2.3 7.7 0.0 5.0 4 1 2 6 6 6 2 CLASP N terminal RTP1_C1 PF10363.9 CCH62081.1 - 0.02 15.1 3.2 13 6.0 0.8 5.5 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CCH62081.1 - 0.048 14.3 3.6 14 6.4 0.1 5.3 3 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 CCH62081.1 - 0.054 13.3 5.9 0.33 10.7 0.1 3.8 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Telomere_reg-2 PF10193.9 CCH62081.1 - 0.12 12.8 9.7 0.31 11.5 0.2 4.8 5 1 0 5 5 5 0 Telomere length regulation protein Sec7_N PF12783.7 CCH62081.1 - 0.13 12.1 9.3 0.25 11.2 2.0 4.2 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ACBP PF00887.19 CCH62082.1 - 7.1e-28 96.7 0.8 7.8e-28 96.5 0.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CCH62082.1 - 0.0039 17.6 0.1 0.12 12.8 0.0 2.0 2 0 0 2 2 2 1 FERM central domain ORMDL PF04061.14 CCH62083.1 - 4.8e-55 185.1 7.1 6.6e-55 184.6 7.1 1.2 1 0 0 1 1 1 1 ORMDL family EF1_GNE PF00736.19 CCH62084.1 - 2.8e-32 110.8 1.5 2.8e-32 110.8 1.5 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CCH62084.1 - 1.7e-11 44.3 4.9 1.7e-11 44.3 4.9 2.9 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 CCH62084.1 - 0.052 13.6 1.2 0.15 12.1 0.0 2.2 2 1 1 3 3 3 0 Glutathione S-transferase, C-terminal domain Fic_N PF13784.6 CCH62084.1 - 0.055 13.5 0.1 0.94 9.6 0.0 2.6 2 0 0 2 2 2 0 Fic/DOC family N-terminal GST_C PF00043.25 CCH62084.1 - 0.2 11.9 3.4 1.8 8.8 1.0 2.8 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SNF5 PF04855.12 CCH62085.1 - 4.4e-46 157.6 3.6 7.9e-26 91.3 0.2 2.5 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 dCMP_cyt_deam_1 PF00383.23 CCH62086.1 - 8.4e-10 38.4 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCH62086.1 - 5.8e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 MafB19-like deaminase AIP3 PF03915.13 CCH62087.1 - 4.9e-123 411.2 27.0 4.9e-123 411.2 27.0 2.3 2 0 0 2 2 2 1 Actin interacting protein 3 DNA_pol3_a_NI PF14480.6 CCH62087.1 - 0.0076 16.2 2.8 0.017 15.1 0.7 2.7 2 0 0 2 2 2 1 DNA polymerase III polC-type N-terminus I Tweety PF04906.13 CCH62087.1 - 0.39 9.3 3.7 0.61 8.7 0.0 2.8 3 0 0 3 3 3 0 Tweety SANT_DAMP1_like PF16282.5 CCH62089.1 - 3.1e-22 78.5 6.6 6.6e-19 67.9 1.5 3.1 3 0 0 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 CCH62089.1 - 0.0019 18.3 0.4 0.015 15.5 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cullin PF00888.22 CCH62090.1 - 1.2e-117 394.1 39.8 1.2e-117 394.1 39.8 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CCH62090.1 - 2.5e-22 78.7 4.1 2.9e-22 78.5 1.1 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Laterosporulin PF17861.1 CCH62090.1 - 0.21 12.0 0.1 0.82 10.1 0.0 2.0 2 0 0 2 2 2 0 Laterosporulin defensin-like peptide Pex24p PF06398.11 CCH62091.1 - 1.5e-49 169.0 16.5 2.6e-49 168.2 16.5 1.3 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Holin_BhlA PF10960.8 CCH62091.1 - 0.0046 16.9 0.9 0.0046 16.9 0.9 2.0 2 0 0 2 2 2 1 BhlA holin family Ribosomal_L38e PF01781.18 CCH62092.1 - 6.7e-30 103.0 3.0 7.6e-30 102.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta_N PF17683.1 CCH62093.1 - 2.9e-35 121.9 9.8 1.6e-34 119.5 9.8 2.2 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CCH62093.1 - 2e-27 95.1 0.7 4.3e-27 94.0 0.7 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 CCH62093.1 - 0.0022 18.8 0.2 0.0022 18.8 0.2 2.4 1 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Prp18 PF02840.15 CCH62094.1 - 1.4e-25 90.0 0.6 2.2e-25 89.4 0.5 1.5 1 1 0 1 1 1 1 Prp18 domain Cas_CXXC_CXXC PF09706.10 CCH62094.1 - 0.074 13.3 1.5 0.092 13.0 0.4 1.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) WD40 PF00400.32 CCH62095.1 - 3.7e-20 71.9 13.6 0.0018 19.1 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62095.1 - 3e-14 53.1 11.6 1.4e-08 35.0 0.2 4.2 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH62095.1 - 8.2e-08 32.4 0.5 0.0015 18.4 0.1 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 CCH62095.1 - 0.036 14.1 0.1 4 7.5 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 CCH62095.1 - 0.07 12.1 0.1 0.28 10.1 0.0 2.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Rep_fac-A_C PF08646.10 CCH62096.1 - 2.4e-60 202.5 4.1 9.8e-59 197.3 1.7 2.9 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CCH62096.1 - 1.3e-32 111.6 1.0 8.9e-30 102.5 0.1 3.4 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CCH62096.1 - 7.5e-18 64.3 1.0 2.8e-10 40.1 0.0 4.5 4 1 0 4 4 4 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CCH62096.1 - 6.4e-09 35.9 0.0 1.8e-05 24.6 0.0 3.3 2 1 0 2 2 2 2 Cell division control protein 24, OB domain 3 Rep-A_N PF04057.12 CCH62096.1 - 9.7e-05 22.3 0.1 0.00083 19.3 0.0 2.5 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.14 CCH62096.1 - 0.026 14.8 3.9 0.037 14.3 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 DUF4539 PF15072.6 CCH62096.1 - 0.038 14.0 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) tRNA_anti_2 PF13742.6 CCH62096.1 - 0.049 13.8 0.0 0.34 11.1 0.0 2.4 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain EPL1 PF10513.9 CCH62096.1 - 0.12 12.7 6.1 0.37 11.2 0.3 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Flocculin PF00624.18 CCH62097.1 - 4.2e-20 71.7 102.5 1.9e-11 44.0 16.5 36.6 35 3 2 37 37 37 8 Flocculin repeat Ank_2 PF12796.7 CCH62099.1 - 2.3e-13 50.5 0.2 7.9e-13 48.8 0.0 2.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCH62099.1 - 4.4e-11 42.8 0.1 7.9e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH62099.1 - 1.5e-09 37.3 0.0 0.00013 22.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CCH62099.1 - 2.7e-09 37.0 0.0 5e-06 26.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CCH62099.1 - 7e-09 36.1 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Phage_Arf PF17585.2 CCH62099.1 - 0.024 14.6 1.8 0.24 11.4 0.0 3.1 2 1 1 3 3 3 0 Accessory recombination function protein SapB_1 PF05184.15 CCH62099.1 - 0.098 12.7 0.1 0.3 11.2 0.1 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 1 RTP1_C1 PF10363.9 CCH62100.1 - 9.1e-29 99.9 1.0 9.1e-29 99.9 1.0 3.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CPSF100_C PF13299.6 CCH62100.1 - 0.012 15.8 1.6 0.024 14.8 1.6 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DegT_DnrJ_EryC1 PF01041.17 CCH62100.1 - 0.016 14.5 0.1 0.032 13.5 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PHD_Oberon PF07227.11 CCH62100.1 - 0.035 14.0 0.6 13 5.7 0.0 3.3 3 0 0 3 3 3 0 PHD - plant homeodomain finger protein RTP1_C2 PF10304.9 CCH62100.1 - 0.038 13.7 0.2 0.12 12.1 0.2 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 HSP90 PF00183.18 CCH62101.1 - 3.1e-218 725.9 34.0 4.6e-218 725.3 34.0 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CCH62101.1 - 4e-15 56.3 0.0 7.6e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCH62101.1 - 2.8e-09 36.9 0.0 7.3e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tau95 PF09734.9 CCH62101.1 - 2.1 9.2 5.6 2.1 9.1 3.1 2.3 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TBCC PF07986.12 CCH62102.1 - 3e-08 33.4 4.3 1.1e-07 31.5 4.3 2.0 1 1 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CCH62102.1 - 0.02 15.4 2.3 0.02 15.4 2.3 2.3 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Sec2p PF06428.11 CCH62102.1 - 0.03 14.3 0.8 0.03 14.3 0.8 2.7 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p UAA PF08449.11 CCH62103.1 - 6.7e-39 133.9 17.4 7.9e-39 133.6 17.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CCH62103.1 - 3.8e-08 33.6 20.6 9.7e-08 32.3 5.7 3.5 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.16 CCH62103.1 - 6e-07 29.1 12.4 0.00019 20.9 3.7 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family Rhomboid PF01694.22 CCH62104.1 - 2e-19 70.1 12.2 3.4e-19 69.3 12.2 1.3 1 0 0 1 1 1 1 Rhomboid family Ribosomal_S17 PF00366.20 CCH62105.1 - 1.2e-21 76.6 0.4 2.1e-21 75.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 TPD52 PF04201.15 CCH62105.1 - 0.016 14.8 4.0 0.066 12.8 1.0 2.3 1 1 1 2 2 2 0 Tumour protein D52 family YlbD_coat PF14071.6 CCH62105.1 - 1.8 8.8 10.4 0.19 12.0 5.4 2.1 2 1 0 2 2 2 0 Putative coat protein GDC-P PF02347.16 CCH62106.1 - 2.6e-188 626.2 0.0 1.3e-177 591.0 0.0 2.7 2 1 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 CCH62106.1 - 0.00031 19.4 0.0 0.0011 17.6 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme AstB PF04996.12 CCH62106.1 - 0.027 13.2 0.0 0.048 12.3 0.0 1.3 1 0 0 1 1 1 0 Succinylarginine dihydrolase Beta_elim_lyase PF01212.21 CCH62106.1 - 0.06 12.6 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CCH62107.1 - 1.3e-38 133.1 0.0 2.1e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCH62107.1 - 0.0062 15.9 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4667 PF15700.5 CCH62108.1 - 1.7e-24 87.3 9.1 3.5e-22 79.7 9.1 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4667) SPX PF03105.19 CCH62109.1 - 1.4e-35 123.9 13.1 5.7e-16 59.4 8.5 4.1 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 CCH62109.1 - 2e-26 93.1 38.6 2.8e-26 92.6 38.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CCH62109.1 - 8.2e-23 81.0 52.1 3.5e-18 65.8 20.5 2.5 2 1 1 3 3 3 2 Citrate transporter DUF373 PF04123.13 CCH62109.1 - 0.013 15.0 25.5 0.041 13.3 9.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF373) DUF835 PF05763.12 CCH62109.1 - 0.043 13.6 1.7 0.12 12.1 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF835) CBF PF03914.17 CCH62109.1 - 0.051 13.6 0.7 0.13 12.3 0.7 1.6 1 0 0 1 1 1 0 CBF/Mak21 family PFK PF00365.20 CCH62110.1 - 5e-184 610.1 2.1 2.2e-101 339.0 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Porin_3 PF01459.22 CCH62111.1 - 1.2e-86 290.6 0.2 1.4e-86 290.3 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Med9 PF07544.13 CCH62112.1 - 4.7e-22 77.9 2.4 1e-21 76.8 2.4 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 SPAM PF02090.15 CCH62112.1 - 0.0048 16.7 1.4 0.0068 16.2 1.4 1.2 1 0 0 1 1 1 1 Salmonella surface presentation of antigen gene type M protein Phage_HK97_TLTM PF06120.11 CCH62112.1 - 0.011 14.9 4.7 0.011 14.9 4.7 1.6 1 1 1 2 2 2 0 Tail length tape measure protein Cortex-I_coil PF09304.10 CCH62112.1 - 0.02 15.1 5.1 0.032 14.4 5.1 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Sipho_Gp157 PF05565.11 CCH62112.1 - 0.036 14.1 4.4 0.062 13.3 4.4 1.4 1 0 0 1 1 1 0 Siphovirus Gp157 DUF3243 PF11588.8 CCH62112.1 - 0.075 13.4 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) FAM76 PF16046.5 CCH62112.1 - 0.26 10.6 2.7 0.43 9.9 2.7 1.4 1 0 0 1 1 1 0 FAM76 protein Whi5 PF08528.11 CCH62113.1 - 2.1e-05 24.0 0.4 4.1e-05 23.1 0.4 1.5 1 0 0 1 1 1 1 Whi5 like Fibrinogen_C PF00147.18 CCH62113.1 - 0.11 12.3 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain XPA_C PF05181.12 CCH62114.1 - 2.7e-21 75.3 0.3 5.1e-21 74.4 0.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Cytochrome_C554 PF13435.6 CCH62114.1 - 8.6 7.4 7.1 19 6.2 0.6 3.0 2 1 0 2 2 2 0 Cytochrome c554 and c-prime Cyclin_N PF00134.23 CCH62115.1 - 5.5e-33 113.4 0.0 1.1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4621 PF15414.6 CCH62115.1 - 4.1 6.2 8.1 7.4 5.4 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) SAGA-Tad1 PF12767.7 CCH62116.1 - 1.5e-73 247.5 2.7 2.6e-73 246.6 2.7 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Myosin_tail_1 PF01576.19 CCH62117.1 - 0.00072 17.5 41.1 0.0013 16.7 30.3 2.1 1 1 1 2 2 2 2 Myosin tail DUF1664 PF07889.12 CCH62117.1 - 0.33 11.0 21.3 0.42 10.7 3.7 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CCH62117.1 - 2.4 8.3 35.0 0.67 10.1 4.1 3.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Noelin-1 PF12308.8 CCH62117.1 - 6.3 6.8 8.8 3.5 7.7 0.6 3.5 2 1 1 3 3 3 0 Neurogenesis glycoprotein Fer2 PF00111.27 CCH62118.1 - 8.7e-14 51.2 0.5 1.2e-13 50.8 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.8 CCH62119.1 - 5.1e-22 77.9 8.7 1.3e-21 76.6 4.8 2.6 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CCH62119.1 - 1e-14 54.6 3.2 1e-14 54.6 3.2 2.6 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CCH62119.1 - 0.00016 21.6 1.3 0.00016 21.6 1.3 2.4 2 1 0 2 2 2 1 Sec20 Catalase-rel PF06628.12 CCH62119.1 - 0.014 15.6 0.5 0.49 10.6 0.1 2.9 3 0 0 3 3 3 0 Catalase-related immune-responsive Mg_trans_NIPA PF05653.14 CCH62119.1 - 0.041 13.0 0.2 0.054 12.6 0.2 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA Apolipoprotein PF01442.18 CCH62119.1 - 0.18 11.7 3.9 2.6 7.9 0.5 2.9 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Methyltransf_9 PF08003.11 CCH62119.1 - 0.53 9.1 5.3 0.091 11.7 1.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) GPS2_interact PF15784.5 CCH62119.1 - 1.1 9.8 5.9 0.33 11.4 0.8 2.4 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain KTI12 PF08433.10 CCH62119.1 - 1.4 8.3 10.8 0.56 9.6 2.3 2.1 1 1 1 2 2 2 0 Chromatin associated protein KTI12 DUF745 PF05335.13 CCH62119.1 - 3.7 7.2 6.8 0.44 10.3 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 CCH62119.1 - 5.6 6.4 10.3 24 4.4 10.3 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_63 PF03200.16 CCH62120.1 - 1.1e-07 31.1 6.5 4.3e-05 22.5 0.2 4.1 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain DUF4019 PF13211.6 CCH62120.1 - 0.019 15.3 0.0 0.069 13.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) RabGAP-TBC PF00566.18 CCH62122.1 - 8.5e-52 175.9 0.4 8.5e-52 175.9 0.4 3.3 2 1 1 3 3 3 1 Rab-GTPase-TBC domain KASH_CCD PF14662.6 CCH62122.1 - 0.016 15.0 28.8 0.016 15.1 24.6 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cnn_1N PF07989.11 CCH62122.1 - 1.6 8.9 24.9 0.047 13.9 9.8 3.4 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 CCH62122.1 - 5 7.0 26.9 0.67 9.8 6.1 3.7 1 1 2 3 3 3 0 Septum formation initiator Fungal_trans PF04082.18 CCH62123.1 - 1.4e-18 66.9 16.6 1.4e-18 66.9 16.6 2.9 3 1 0 3 3 3 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CCH62123.1 - 4.2e-11 42.8 2.2 1.9e-10 40.8 0.8 2.6 2 0 0 2 2 2 1 Gal4-like dimerisation domain Zn_clus PF00172.18 CCH62123.1 - 9e-07 28.9 18.4 2e-06 27.8 18.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACC_central PF08326.12 CCH62124.1 - 3.3e-264 878.6 0.0 3.3e-264 878.6 0.0 1.4 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CCH62124.1 - 4.7e-186 619.2 0.0 6.1e-186 618.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CCH62124.1 - 5.9e-52 176.2 0.0 1.5e-51 174.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CCH62124.1 - 2e-29 102.4 0.0 4.2e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCH62124.1 - 4.5e-21 75.0 0.0 2.4e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CCH62124.1 - 2e-18 66.0 0.1 6.7e-18 64.3 0.1 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CCH62124.1 - 0.0037 17.0 0.0 3.3 7.6 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CCH62124.1 - 0.0047 17.0 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CCH62124.1 - 0.0094 15.5 0.0 0.028 13.9 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CCH62124.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon GxGYxYP_N PF16216.5 CCH62124.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal F_bP_aldolase PF01116.20 CCH62125.1 - 2.7e-87 292.8 0.1 3e-87 292.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.11 CCH62125.1 - 0.025 14.7 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Torsin SNAP PF14938.6 CCH62125.1 - 0.041 13.3 0.1 0.069 12.6 0.1 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF89 PF01937.19 CCH62126.1 - 2.9e-109 365.3 3.7 3.3e-109 365.1 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 TAP42 PF04177.12 CCH62127.1 - 1.5e-80 270.8 25.6 1.7e-80 270.6 25.6 1.0 1 0 0 1 1 1 1 TAP42-like family PB1-F2 PF11986.8 CCH62127.1 - 0.022 15.0 0.2 5.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Influenza A Proapoptotic protein ER PF01133.17 CCH62127.1 - 0.069 13.2 0.5 0.069 13.2 0.5 3.1 3 1 1 4 4 4 0 Enhancer of rudimentary DUF573 PF04504.14 CCH62127.1 - 8.7 7.1 11.9 0.38 11.4 4.0 3.0 3 1 0 3 3 3 0 Protein of unknown function, DUF573 adh_short PF00106.25 CCH62128.1 - 8.9e-21 74.2 0.4 3.4e-12 46.2 0.2 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCH62128.1 - 1e-06 28.5 0.0 1.3e-05 24.9 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH62128.1 - 0.00017 21.5 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 2 KR domain Frag1 PF10277.9 CCH62129.1 - 6.1e-71 238.4 9.6 8.1e-71 238.0 9.6 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Mem_trans PF03547.18 CCH62129.1 - 0.0087 14.5 0.0 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein Eisosome1 PF12757.7 CCH62130.1 - 5e-26 91.4 0.5 5e-26 91.4 0.5 4.2 6 0 0 6 6 6 1 Eisosome protein 1 FCH PF00611.23 CCH62131.1 - 3.5e-10 40.0 0.1 3.5e-10 40.0 0.1 3.2 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CCH62131.1 - 0.0015 18.1 0.0 0.0036 16.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain Histone PF00125.24 CCH62132.1 - 3.5e-35 121.2 2.0 3.5e-35 121.2 2.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CCH62132.1 - 0.011 15.8 0.1 0.025 14.7 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CCH62132.1 - 0.051 14.0 0.1 0.092 13.1 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein Pkinase PF00069.25 CCH62133.1 - 9.5e-33 113.7 0.0 2.6e-26 92.6 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62133.1 - 2.1e-21 76.4 0.5 1.5e-12 47.3 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 CCH62133.1 - 0.00023 20.6 0.0 0.00085 18.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCH62133.1 - 0.047 12.5 0.0 0.091 11.5 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CCH62133.1 - 0.072 13.0 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CCH62134.1 - 1.9e-11 43.7 12.2 2.1e-05 24.7 2.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH62134.1 - 1e-09 38.4 12.0 7.6e-05 23.2 1.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCH62134.1 - 1e-07 32.0 17.1 1.8e-06 28.1 3.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCH62134.1 - 8.3e-07 29.1 7.9 0.0005 20.3 2.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CCH62134.1 - 0.0011 19.0 5.3 0.53 10.4 0.6 2.9 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.6 CCH62134.1 - 0.0029 17.5 3.1 0.0029 17.5 3.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CCH62134.1 - 0.0065 16.7 3.5 0.015 15.6 3.5 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CCH62134.1 - 0.008 16.5 4.4 0.048 14.1 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CCH62134.1 - 0.053 14.0 8.7 0.44 11.0 1.0 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Nanovirus_coat PF04660.12 CCH62134.1 - 0.089 12.8 0.8 0.69 9.9 0.1 2.4 2 0 0 2 2 2 0 Nanovirus coat protein zf-C2H2_3rep PF18868.1 CCH62134.1 - 0.11 13.1 2.3 0.45 11.2 1.6 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CCH62134.1 - 0.18 11.6 17.1 0.078 12.7 2.3 3.5 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF629 PF04780.12 CCH62134.1 - 2.8 6.4 6.8 1.5 7.3 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 CCH62134.1 - 9.4 6.6 14.6 2.7 8.4 0.4 3.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) CorA PF01544.18 CCH62135.1 - 3.2e-39 135.0 3.2 1.2e-21 77.4 0.1 3.7 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein PC4 PF02229.16 CCH62136.1 - 1.8e-22 78.7 0.1 3.3e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Virul_Fac PF10139.9 CCH62136.1 - 1 7.5 7.4 0.031 12.5 1.4 1.4 2 0 0 2 2 2 0 Putative bacterial virulence factor XAP5 PF04921.14 CCH62136.1 - 6.2 6.6 15.5 0.28 11.0 9.3 1.8 2 0 0 2 2 2 0 XAP5, circadian clock regulator Bap31 PF05529.12 CCH62137.1 - 1.8e-18 66.7 1.0 4.1e-18 65.5 1.0 1.6 1 1 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CCH62137.1 - 0.23 11.5 3.5 0.12 12.4 1.4 1.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain SRF-TF PF00319.18 CCH62138.1 - 7.1e-21 73.4 0.2 1.1e-20 72.8 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GST_N_2 PF13409.6 CCH62139.1 - 1.6e-15 57.2 0.0 5.8e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCH62139.1 - 6.4e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCH62139.1 - 0.094 13.1 0.0 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCH62140.1 - 8.3e-11 42.0 0.1 1.3e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCH62140.1 - 1.4e-05 25.2 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH62140.1 - 7.4e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCH62140.1 - 0.0015 18.9 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PX PF00787.24 CCH62140.1 - 0.013 15.4 0.6 0.036 14.1 0.2 1.8 2 1 0 2 2 2 0 PX domain Sod_Fe_C PF02777.18 CCH62141.1 - 2.3e-13 50.2 1.5 3.9e-11 43.0 1.5 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Cu PF00080.20 CCH62142.1 - 5.1e-43 146.6 2.9 5.8e-43 146.5 2.9 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Kei1 PF08552.11 CCH62143.1 - 1.7e-36 125.9 16.9 5.6e-34 117.7 16.9 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF5445 PF17520.2 CCH62143.1 - 1.1 9.2 4.8 0.22 11.4 0.5 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5445) Helicase_C PF00271.31 CCH62145.1 - 3.2e-16 59.6 0.1 1.3e-15 57.7 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCH62145.1 - 2.9e-12 46.8 0.0 9.2e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 CCH62145.1 - 6.3e-11 42.6 3.9 6.3e-11 42.6 3.9 2.9 2 1 0 2 2 2 1 RWD domain DEAD PF00270.29 CCH62145.1 - 9.1e-09 35.3 1.3 3.3e-08 33.5 1.3 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 CCH62145.1 - 1.1e-05 25.6 0.0 1.1e-05 25.6 0.0 3.0 3 0 0 3 3 2 1 Helicase associated domain (HA2) AAA_19 PF13245.6 CCH62145.1 - 0.00018 21.9 0.1 0.00058 20.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCH62145.1 - 0.0012 18.3 2.1 0.0017 17.7 0.0 2.3 3 0 0 3 3 3 1 KaiC AAA_22 PF13401.6 CCH62145.1 - 0.0012 19.1 1.7 0.0083 16.4 0.1 2.9 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 CCH62145.1 - 0.0016 17.5 0.1 0.0038 16.3 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 CCH62145.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 CCH62145.1 - 0.015 14.8 0.1 0.044 13.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CCH62145.1 - 0.024 14.5 0.0 0.091 12.7 0.0 2.0 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 CCH62145.1 - 0.031 14.8 0.1 0.031 14.8 0.1 5.4 2 1 1 4 4 3 0 AAA domain AAA_16 PF13191.6 CCH62145.1 - 0.033 14.6 0.0 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 CCH62145.1 - 0.04 13.5 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 CCH62145.1 - 0.053 13.1 0.1 0.17 11.5 0.1 2.0 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.18 CCH62145.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glyco_hydro_4C PF11975.8 CCH62145.1 - 0.075 13.1 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain AAA_30 PF13604.6 CCH62145.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CCH62145.1 - 0.11 12.0 0.2 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 CCH62145.1 - 1.3 9.5 5.0 0.78 10.3 0.0 3.1 3 0 0 3 3 2 0 ABC transporter Vps36_ESCRT-II PF11605.8 CCH62146.1 - 4.2e-32 110.2 0.1 1.2e-31 108.7 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 CCH62146.1 - 4.2e-24 85.1 0.2 6.4e-24 84.5 0.2 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 CCH62146.1 - 2.3e-20 71.7 1.3 2.3e-20 71.7 1.3 2.8 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 CCH62146.1 - 0.0017 18.3 4.0 0.0096 15.9 0.5 2.4 2 0 0 2 2 2 1 Double zinc ribbon zf-RanBP PF00641.18 CCH62146.1 - 0.0021 17.3 8.6 0.0024 17.1 0.7 2.9 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others bPH_3 PF14470.6 CCH62146.1 - 0.0052 17.1 0.1 0.017 15.5 0.1 1.9 1 0 0 1 1 1 1 Bacterial PH domain GRAM PF02893.20 CCH62146.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 GRAM domain zf-Sec23_Sec24 PF04810.15 CCH62146.1 - 0.014 15.4 11.7 0.49 10.5 2.0 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger CNOT1_TTP_bind PF16417.5 CCH62146.1 - 0.14 11.4 2.9 0.22 10.7 0.7 2.3 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Cas_CXXC_CXXC PF09706.10 CCH62146.1 - 1.7 9.0 9.5 9.1 6.6 0.5 3.8 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zinc_ribbon_15 PF17032.5 CCH62146.1 - 2.4 9.0 6.2 7.7 7.3 5.7 2.1 1 1 1 2 2 2 0 zinc-ribbon family ABC_membrane_2 PF06472.15 CCH62147.1 - 1e-64 218.6 12.5 7.3e-42 143.6 1.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCH62147.1 - 7.5e-16 58.9 1.1 1.4e-14 54.8 0.0 3.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CCH62147.1 - 0.00022 21.2 0.1 0.00022 21.2 0.1 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH62147.1 - 0.037 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH62147.1 - 0.042 14.1 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Phage_holin_2_1 PF04971.12 CCH62147.1 - 0.096 12.7 0.1 0.096 12.7 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S RuvB_N PF05496.12 CCH62147.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain SUR7 PF06687.12 CCH62148.1 - 4.6e-33 114.6 13.5 5.7e-33 114.3 13.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF2070 PF09843.9 CCH62148.1 - 0.088 11.1 1.3 0.13 10.5 1.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CcmE PF03100.15 CCH62148.1 - 0.69 9.9 0.0 0.69 9.9 0.0 2.2 3 0 0 3 3 3 0 CcmE LapA_dom PF06305.11 CCH62148.1 - 1.8 8.5 7.9 0.15 11.9 1.6 2.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain adh_short PF00106.25 CCH62149.1 - 1.8e-22 79.8 0.0 2.2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH62149.1 - 6.9e-11 42.2 0.0 8.6e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 CCH62149.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Herpes_PAP PF03325.13 CCH62149.1 - 0.03 13.9 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein KR PF08659.10 CCH62149.1 - 0.033 14.1 1.0 2.9 7.8 0.1 2.9 2 1 0 2 2 2 0 KR domain BsuBI_PstI_RE PF06616.11 CCH62149.1 - 0.11 11.8 0.3 0.54 9.5 0.1 2.0 2 0 0 2 2 2 0 BsuBI/PstI restriction endonuclease domain DUF1951 PF09188.10 CCH62149.1 - 1 9.3 5.1 4.4 7.3 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1951) SPC25 PF06703.11 CCH62150.1 - 6.3e-39 133.4 2.0 7.1e-39 133.2 2.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DDE_Tnp_1_3 PF13612.6 CCH62150.1 - 0.0027 17.7 0.3 0.0046 17.0 0.3 1.4 1 0 0 1 1 1 1 Transposase DDE domain DUF1899 PF08953.11 CCH62151.1 - 2e-31 107.7 0.9 2e-31 107.7 0.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CCH62151.1 - 5.4e-17 61.4 0.5 5.4e-17 61.4 0.5 1.9 2 0 0 2 2 2 1 Type of WD40 repeat WD40 PF00400.32 CCH62151.1 - 5.8e-17 61.8 3.9 0.00017 22.3 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CCH62151.1 - 6.5e-06 25.1 3.5 0.00063 18.5 0.0 2.6 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCH62151.1 - 8.2e-05 22.8 0.0 0.028 14.7 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCH62151.1 - 0.0025 17.7 0.2 0.25 11.2 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CCH62151.1 - 0.018 13.6 0.1 0.029 12.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 CCH62151.1 - 0.027 13.4 0.0 0.93 8.4 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SlyX PF04102.12 CCH62151.1 - 0.42 11.3 6.3 0.06 14.0 2.1 1.9 2 0 0 2 2 2 0 SlyX SEN1_N PF12726.7 CCH62152.1 - 9.6e-199 662.3 22.0 9.6e-199 662.3 22.0 1.7 2 0 0 2 2 2 1 SEN1 N terminal AAA_11 PF13086.6 CCH62152.1 - 9.7e-75 251.7 0.3 9.7e-75 251.7 0.3 3.9 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CCH62152.1 - 3.4e-61 206.3 0.0 9.3e-61 204.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH62152.1 - 5.2e-09 36.6 0.0 3.3e-08 34.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCH62152.1 - 7.5e-09 35.6 0.0 9.5e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CCH62152.1 - 0.0022 17.8 0.0 1.1 8.9 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF3813 PF12758.7 CCH62152.1 - 0.044 14.1 1.2 5.7 7.4 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Metallophos PF00149.28 CCH62154.1 - 1.5e-26 94.2 1.2 1.5e-26 94.2 1.2 4.0 2 2 1 3 3 3 1 Calcineurin-like phosphoesterase WGG PF10273.9 CCH62155.1 - 1.3e-27 96.3 1.3 2.5e-27 95.4 1.3 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RNR_inhib PF08591.10 CCH62156.1 - 0.72 11.2 5.4 0.16 13.3 1.7 1.9 2 1 0 2 2 2 0 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.21 CCH62157.1 - 1e-114 383.4 0.0 1.2e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CCH62157.1 - 0.028 13.6 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Sec39 PF08314.11 CCH62158.1 - 1.9e-93 314.3 33.6 2.5e-92 310.7 33.6 2.0 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Phage_int_SAM_4 PF13495.6 CCH62158.1 - 9.7 6.7 9.6 8.6 6.9 0.1 3.7 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain BAH PF01426.18 CCH62159.1 - 2e-13 50.2 0.8 1.1e-12 47.8 0.8 2.4 1 0 0 1 1 1 1 BAH domain AAA_lid_10 PF17872.1 CCH62159.1 - 0.0004 20.4 0.9 0.0004 20.4 0.9 3.1 2 0 0 2 2 2 1 AAA lid domain SUR7 PF06687.12 CCH62160.1 - 3e-08 33.5 12.9 6.4e-08 32.5 12.9 1.6 1 0 0 1 1 1 1 SUR7/PalI family Fur_reg_FbpB PF13040.6 CCH62161.1 - 0.078 12.5 4.6 0.27 10.8 4.6 2.0 1 0 0 1 1 1 0 Fur-regulated basic protein B Acetyltransf_1 PF00583.25 CCH62162.1 - 1.1e-05 25.6 0.2 4.9e-05 23.5 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCH62162.1 - 1.7e-05 25.1 0.0 4.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4811 PF16069.5 CCH62162.1 - 0.0028 17.6 0.9 0.0048 16.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4811) Acetyltransf_16 PF05301.11 CCH62162.1 - 0.0031 17.3 0.4 0.0059 16.4 0.3 1.5 1 1 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_10 PF13673.7 CCH62162.1 - 0.0038 17.2 0.1 0.017 15.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1910 PF08928.10 CCH62162.1 - 0.015 15.2 0.1 0.015 15.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Acetyltransf_CG PF14542.6 CCH62162.1 - 0.026 14.6 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TFIID-18kDa PF02269.16 CCH62162.1 - 0.042 13.9 0.5 3 7.9 0.1 2.7 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit zf-C2H2_4 PF13894.6 CCH62163.1 - 1.1e-06 28.9 15.4 0.00011 22.8 4.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CCH62163.1 - 4.9e-06 26.7 3.6 8.4e-06 26.0 3.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 CCH62163.1 - 7.7e-06 26.1 4.5 7.7e-06 26.1 4.5 3.1 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH62163.1 - 0.00018 21.8 13.6 0.23 12.0 0.3 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 CCH62163.1 - 0.0068 16.7 8.4 0.34 11.3 1.2 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 CCH62163.1 - 0.015 15.1 21.0 0.11 12.3 5.0 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain UPF0167 PF03691.14 CCH62163.1 - 0.026 14.3 0.7 0.051 13.4 0.5 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) TRAF6_Z2 PF18048.1 CCH62163.1 - 0.026 14.6 2.9 0.029 14.5 0.3 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 Zn-C2H2_12 PF18112.1 CCH62163.1 - 0.068 13.6 1.0 0.068 13.6 1.0 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 CCH62163.1 - 0.24 11.6 2.8 0.44 10.7 1.8 2.0 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_9 PF16293.5 CCH62163.1 - 0.24 11.3 5.4 0.72 9.7 0.1 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-UDP PF14569.6 CCH62163.1 - 1.5 9.0 8.4 3.6 7.8 1.4 3.1 2 1 1 3 3 3 0 Zinc-binding RING-finger zf-C2H2_6 PF13912.6 CCH62163.1 - 6 7.0 8.0 0.22 11.6 1.7 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Cg6151-P PF10233.9 CCH62164.1 - 1.5e-38 131.6 15.7 1.9e-38 131.3 15.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P HMG_box PF00505.19 CCH62166.1 - 9e-33 112.5 9.9 1.6e-17 63.6 2.1 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CCH62166.1 - 1.8e-17 63.7 6.1 1.9e-09 38.0 1.8 2.7 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 CCH62166.1 - 3.2e-11 43.0 0.3 0.00011 22.0 0.0 3.5 4 0 0 4 4 4 2 CHDNT (NUC034) domain dsDNA_bind PF01984.20 CCH62167.1 - 7.5e-23 80.9 2.2 1.3e-22 80.2 2.2 1.4 1 1 0 1 1 1 1 Double-stranded DNA-binding domain Glu_cyclase_2 PF05096.12 CCH62167.1 - 0.095 12.1 0.1 9.4 5.6 0.1 2.0 1 1 1 2 2 2 0 Glutamine cyclotransferase EF-1_beta_acid PF10587.9 CCH62167.1 - 0.12 12.8 0.5 0.12 12.8 0.5 2.9 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region PHD PF00628.29 CCH62168.1 - 5.6e-15 55.0 18.5 3.5e-11 42.8 8.0 3.0 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 CCH62168.1 - 0.0028 17.9 6.3 0.0091 16.2 1.4 2.8 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CCH62168.1 - 0.62 9.7 8.0 7.3 6.2 0.1 3.5 3 0 0 3 3 3 0 PHD-finger LON_substr_bdg PF02190.16 CCH62169.1 - 0.69 9.7 8.7 1.3 8.8 4.8 3.3 1 1 1 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain Stap_Strp_toxin PF01123.20 CCH62169.1 - 7.2 7.5 7.2 25 5.8 1.1 4.5 4 0 0 4 4 4 0 Staphylococcal/Streptococcal toxin, OB-fold domain Cnd1 PF12717.7 CCH62169.1 - 9.2 6.3 17.0 0.19 11.8 0.7 5.6 7 1 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Form_Nir_trans PF01226.17 CCH62170.1 - 2.9e-55 187.2 23.7 3.7e-55 186.9 23.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BRAP2 PF07576.12 CCH62171.1 - 1.2e-26 92.8 3.9 3.6e-25 88.1 1.3 2.6 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CCH62171.1 - 1.9e-20 72.9 7.5 1.9e-20 72.9 7.5 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CCH62171.1 - 1.8e-08 34.6 11.6 1.8e-08 34.6 11.6 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCH62171.1 - 3.6e-06 26.7 11.3 3.6e-06 26.7 11.3 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCH62171.1 - 1.4e-05 24.7 6.2 4.9e-05 23.0 6.2 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CCH62171.1 - 1.6e-05 25.1 7.3 6.2e-05 23.2 7.3 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CCH62171.1 - 1.7e-05 24.7 5.6 1.7e-05 24.7 5.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCH62171.1 - 6.2e-05 22.8 7.6 6.2e-05 22.8 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH62171.1 - 0.00011 22.0 9.9 0.00011 22.0 9.9 2.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCH62171.1 - 0.00013 21.8 12.0 0.00037 20.3 12.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH62171.1 - 0.0034 17.2 8.2 0.0034 17.2 8.2 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CCH62171.1 - 0.014 15.4 4.2 0.039 14.0 4.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CCH62171.1 - 0.028 14.2 7.9 0.07 12.9 7.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UBP_var PF17807.1 CCH62171.1 - 0.045 13.5 1.0 0.11 12.2 1.0 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger zf-C3HC4_4 PF15227.6 CCH62171.1 - 0.38 11.0 7.4 1.9 8.7 7.5 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF641 PF04859.12 CCH62171.1 - 2.9 8.3 13.6 3.7 7.9 6.1 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Pribosyltran_N PF13793.6 CCH62172.1 - 1.4e-34 118.5 0.1 2.2e-32 111.4 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCH62172.1 - 2.6e-27 96.0 8.9 6e-24 85.1 5.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCH62172.1 - 8.3e-07 28.7 0.6 2.3e-06 27.2 0.6 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HAD_2 PF13419.6 CCH62173.1 - 1.4e-22 80.6 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCH62173.1 - 4.8e-12 46.6 0.0 2.1e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CCH62173.1 - 1e-05 25.6 0.0 0.0028 17.8 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CCH62173.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UDPGP PF01704.18 CCH62174.1 - 3.2e-184 612.3 0.0 4.7e-184 611.8 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 CCH62174.1 - 0.031 13.1 0.1 0.089 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Zn_clus PF00172.18 CCH62175.1 - 2.7e-08 33.8 8.9 5.2e-08 32.9 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.19 CCH62176.1 - 7.2e-19 68.5 0.4 1.3e-18 67.7 0.1 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CCH62176.1 - 0.00091 18.7 0.1 0.018 14.5 0.0 2.2 1 1 0 1 1 1 1 Peptidase C65 Otubain eIF3_subunit PF08597.10 CCH62176.1 - 0.0073 16.3 3.8 0.009 16.0 3.8 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Cpn60_TCP1 PF00118.24 CCH62177.1 - 4.5e-146 487.3 3.2 5.1e-146 487.2 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family POTRA_1 PF08478.10 CCH62177.1 - 0.57 10.5 2.1 14 6.1 0.0 3.1 2 1 1 3 3 3 0 POTRA domain, FtsQ-type COG6 PF06419.11 CCH62179.1 - 1.1e-139 466.6 40.5 1.1e-139 466.6 40.5 1.4 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Phage_Integr_2 PF13009.6 CCH62179.1 - 2.4 7.2 6.8 3.1 6.8 0.4 2.9 3 0 0 3 3 3 0 Putative phage integrase Vac_Fusion PF02346.16 CCH62179.1 - 3 7.6 4.8 23 4.7 0.1 3.9 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Diphthamide_syn PF01866.17 CCH62180.1 - 3.9e-114 381.2 0.1 4.7e-114 380.9 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.15 CCH62181.1 - 1.2e-69 233.4 3.2 1.9e-69 232.8 3.2 1.3 1 0 0 1 1 1 1 SHQ1 protein DUF5383 PF17355.2 CCH62181.1 - 0.024 15.0 1.4 0.024 15.0 1.4 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5383) ENTH PF01417.20 CCH62181.1 - 0.065 13.3 0.7 0.23 11.5 0.7 1.9 1 0 0 1 1 1 0 ENTH domain DUF2722 PF10846.8 CCH62182.1 - 1.4e-21 77.0 48.8 1.1e-18 67.5 48.8 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) PRA1 PF03208.19 CCH62183.1 - 2.2e-39 134.4 0.2 2.6e-39 134.1 0.2 1.1 1 0 0 1 1 1 1 PRA1 family protein Peptidase_M1 PF01433.20 CCH62184.1 - 1.4e-49 168.6 1.9 2.4e-49 167.9 1.9 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CCH62184.1 - 7.5e-37 125.9 0.1 2.2e-36 124.4 0.1 1.9 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CCH62184.1 - 1.2e-35 123.4 0.3 2.5e-35 122.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 CCH62184.1 - 0.063 12.9 0.1 0.29 10.8 0.1 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M64 PF09471.10 CCH62184.1 - 0.081 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M48 PF01435.18 CCH62184.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_M61 PF05299.12 CCH62184.1 - 1 9.8 3.8 8.4 6.8 2.0 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase PH PF00169.29 CCH62185.1 - 1e-09 38.8 0.8 4.3e-09 36.8 0.8 2.2 1 0 0 1 1 1 1 PH domain 6PF2K PF01591.18 CCH62186.1 - 1.3e-77 260.0 4.7 2.7e-77 259.1 4.7 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCH62186.1 - 5.6e-28 98.0 0.0 3.5e-24 85.6 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCH62186.1 - 8.5e-05 22.7 0.0 0.00033 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCH62186.1 - 0.00014 22.5 0.0 0.00063 20.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCH62186.1 - 0.0027 17.2 0.7 0.0058 16.1 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CCH62186.1 - 0.0035 17.8 0.0 0.012 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CCH62186.1 - 0.0077 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Pox_A28 PF04584.14 CCH62186.1 - 0.0088 16.2 0.2 0.027 14.7 0.2 1.8 1 0 0 1 1 1 1 Poxvirus A28 family APS_kinase PF01583.20 CCH62186.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase ECD PF18432.1 CCH62186.1 - 0.031 14.2 0.4 0.1 12.6 0.4 1.8 1 0 0 1 1 1 0 Extracellular Cadherin domain Sec23_trunk PF04811.15 CCH62187.1 - 2.1e-66 224.0 0.0 4e-66 223.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCH62187.1 - 1.3e-20 73.2 0.4 4.6e-20 71.4 0.2 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCH62187.1 - 2e-17 63.0 5.3 4.1e-17 61.9 5.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CCH62187.1 - 3.9e-16 59.6 0.3 1.3e-15 57.9 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CCH62187.1 - 3.5e-10 39.6 0.0 9.5e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat NR_Repeat PF14046.6 CCH62187.1 - 2.7 8.2 8.4 0.28 11.3 3.3 2.0 2 0 0 2 2 2 0 Nuclear receptor repeat DUF5376 PF17346.2 CCH62188.1 - 0.25 11.7 2.6 0.25 11.7 0.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5376) Ank_2 PF12796.7 CCH62189.1 - 1.6e-32 111.9 0.1 2.5e-13 50.4 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCH62189.1 - 7.3e-29 99.5 1.2 1.1e-08 35.2 0.3 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH62189.1 - 7.3e-29 99.8 1.9 1.1e-09 38.6 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH62189.1 - 2.3e-23 79.7 1.0 8.7e-07 28.8 0.2 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CCH62189.1 - 7.3e-21 73.6 4.3 1.2e-06 28.7 0.2 5.4 5 0 0 5 5 5 3 Ankyrin repeat DSPc PF00782.20 CCH62190.1 - 4.7e-36 123.5 2.3 4.7e-36 123.5 2.3 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCH62190.1 - 4.7e-05 23.1 0.8 9.3e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPn PF14671.6 CCH62190.1 - 0.031 14.7 0.6 0.031 14.7 0.6 1.9 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half PTPlike_phytase PF14566.6 CCH62190.1 - 0.094 12.8 0.0 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Vac7 PF12751.7 CCH62191.1 - 1.9e-25 90.1 19.2 9.8e-21 74.6 0.0 7.0 4 2 2 7 7 7 2 Vacuolar segregation subunit 7 DUF4668 PF15701.5 CCH62191.1 - 0.056 13.3 0.7 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) MFS_1 PF07690.16 CCH62193.1 - 3.3e-36 125.0 23.7 5.5e-36 124.2 22.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH62193.1 - 1.2e-14 54.1 5.6 1.2e-14 54.1 5.6 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter SUN PF03856.13 CCH62195.1 - 1.4e-98 329.2 16.1 2.5e-98 328.4 16.1 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) AMP_N PF05195.16 CCH62195.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain adh_short PF00106.25 CCH62196.1 - 4e-46 157.0 0.0 5.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH62196.1 - 1.1e-30 107.0 0.0 1.4e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CCH62196.1 - 1.2e-08 34.7 0.0 1e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CCH62196.1 - 5.8e-08 32.8 0.0 9.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CCH62196.1 - 0.019 14.1 0.0 0.042 12.9 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.26 CCH62196.1 - 0.02 14.9 0.0 0.082 12.9 0.0 1.9 1 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1776 PF08643.10 CCH62196.1 - 0.02 14.2 0.0 0.15 11.4 0.0 2.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 CCH62196.1 - 0.031 13.7 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Calici_coat PF00915.20 CCH62196.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Calicivirus coat protein NAD_binding_10 PF13460.6 CCH62196.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding SNF2_N PF00176.23 CCH62197.1 - 6.1e-75 252.1 0.2 1.9e-74 250.5 0.2 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH62197.1 - 8.3e-23 80.9 0.1 7e-21 74.6 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CCH62197.1 - 7.3e-21 74.0 1.2 2.2e-20 72.5 0.7 2.2 2 0 0 2 2 2 1 Bromodomain HSA PF07529.13 CCH62197.1 - 6e-09 36.1 10.2 6e-09 36.1 10.2 3.3 2 0 0 2 2 2 1 HSA SnAC PF14619.6 CCH62197.1 - 5.5e-07 30.1 0.2 5.5e-07 30.1 0.2 5.1 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex Ribosomal_S13 PF00416.22 CCH62197.1 - 0.046 14.1 2.4 0.4 11.1 2.4 2.7 1 0 0 1 1 1 0 Ribosomal protein S13/S18 MMS19_C PF12460.8 CCH62198.1 - 5.7e-83 279.4 21.2 5.7e-83 279.4 21.2 3.4 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CCH62198.1 - 2.6e-77 260.0 17.8 7.3e-76 255.2 3.6 4.4 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 CCH62198.1 - 2.2e-06 27.8 13.2 0.0093 16.1 0.2 5.0 4 1 1 5 5 5 4 Required for nuclear transport of RNA pol II C-terminus 1 Ipi1_N PF12333.8 CCH62198.1 - 0.024 15.2 0.8 1.2e+02 3.3 0.0 4.5 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.7 CCH62198.1 - 0.026 15.1 4.9 1 10.0 0.0 4.9 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region VHS PF00790.19 CCH62198.1 - 0.065 13.1 1.5 0.28 11.0 0.0 2.9 3 0 0 3 3 3 0 VHS domain V-ATPase_H_C PF11698.8 CCH62198.1 - 0.24 11.5 5.5 1 9.5 0.3 4.3 3 1 0 3 3 3 0 V-ATPase subunit H MGDG_synth PF06925.11 CCH62198.1 - 6.5 6.8 9.8 14 5.7 0.1 4.0 3 1 0 4 4 4 0 Monogalactosyldiacylglycerol (MGDG) synthase Fungal_trans PF04082.18 CCH62199.1 - 1.4e-33 116.0 5.5 1.4e-33 116.0 5.5 3.7 4 2 1 5 5 5 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH62199.1 - 1.2e-11 44.6 11.5 2.5e-11 43.5 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma_reg_N PF13800.6 CCH62199.1 - 5.6 7.3 8.1 10 6.5 3.6 3.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Forkhead PF00250.18 CCH62200.1 - 1.1e-30 105.7 0.6 1.1e-30 105.7 0.6 2.3 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CCH62200.1 - 7.5e-07 29.4 0.0 6.7e-06 26.4 0.0 2.7 1 1 1 2 2 2 1 FHA domain Ribosomal_L13 PF00572.18 CCH62201.1 - 3.6e-11 43.4 0.9 2.5e-09 37.5 0.1 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 Mito_carr PF00153.27 CCH62202.1 - 2.7e-64 213.1 5.6 2.7e-21 75.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR19-TM PF15176.6 CCH62203.1 - 5.9 6.9 8.3 0.39 10.7 1.3 2.5 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain 2-oxoacid_dh PF00198.23 CCH62204.1 - 4.7e-71 238.9 0.3 6e-71 238.6 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CCH62204.1 - 1.9e-14 53.7 0.1 5.1e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 CCH62204.1 - 5.6e-13 48.5 0.0 1.7e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme MSA-2c PF12238.8 CCH62204.1 - 7.9 6.4 8.1 18 5.2 8.1 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c Brix PF04427.18 CCH62205.1 - 3.1e-29 102.4 0.4 4.1e-29 102.1 0.4 1.1 1 0 0 1 1 1 1 Brix domain DUF1752 PF08550.10 CCH62206.1 - 1.1e-08 34.8 0.7 1.1e-08 34.8 0.7 2.1 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DUF4407 PF14362.6 CCH62207.1 - 0.075 12.4 3.8 0.11 11.9 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSF_DNA-bind PF00447.17 CCH62208.1 - 5.8e-31 107.0 3.6 1.2e-30 106.0 3.6 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1633 PF07794.11 CCH62208.1 - 0.014 13.6 1.3 0.02 13.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) RIFIN PF02009.16 CCH62208.1 - 0.027 14.4 2.1 0.039 13.9 2.1 1.3 1 0 0 1 1 1 0 Rifin Mucin PF01456.17 CCH62208.1 - 1.7 8.6 28.0 0.46 10.5 8.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3446 PF11928.8 CCH62208.1 - 2.7 8.4 6.1 2 8.8 0.6 2.7 2 0 0 2 2 2 0 Early growth response N-terminal domain zf-TFIIIC PF12660.7 CCH62209.1 - 6.2e-06 26.1 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex SusF_SusE PF16411.5 CCH62209.1 - 0.0049 17.4 0.0 0.68 10.5 0.0 2.9 2 1 0 2 2 2 1 Outer membrane protein SusF_SusE ANAPC4_WD40 PF12894.7 CCH62209.1 - 0.03 14.6 0.1 0.64 10.4 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S16 PF00886.19 CCH62211.1 - 1.1e-25 89.4 0.1 1.6e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 PDR_assoc PF08370.11 CCH62211.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Nucleoporin_FG PF13634.6 CCH62212.1 - 1.4e-32 112.4 223.2 6e-11 43.0 42.1 4.4 1 1 4 5 5 5 5 Nucleoporin FG repeat region zf-C4H2 PF10146.9 CCH62212.1 - 0.0014 19.0 1.9 0.0014 19.0 1.9 1.6 2 0 0 2 2 2 1 Zinc finger-containing protein Nucleoporin_FG2 PF15967.5 CCH62212.1 - 0.016 13.8 53.7 0.0094 14.5 38.9 2.1 1 1 1 2 2 2 0 Nucleoporin FG repeated region DUF1664 PF07889.12 CCH62212.1 - 0.039 14.0 6.5 0.28 11.2 2.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) XRN_N PF03159.18 CCH62213.1 - 6.5e-96 320.4 0.1 6.5e-96 320.4 0.1 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CCH62213.1 - 2.5e-80 270.6 12.4 2.5e-80 270.6 12.4 3.1 2 1 0 2 2 2 1 Xrn1 helical domain XRN1_D1 PF18332.1 CCH62213.1 - 1.3e-68 230.6 0.2 1.3e-68 230.6 0.2 3.0 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain Xrn1_D3 PF18194.1 CCH62213.1 - 4.3e-36 122.9 2.2 8.1e-35 118.8 0.6 3.4 3 0 0 3 3 3 1 Exoribonuclease 1 Domain-3 XRN1_D2_D3 PF18334.1 CCH62213.1 - 8.9e-30 102.7 0.1 8.9e-30 102.7 0.1 2.8 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 CCH62213.1 - 1e-19 70.4 0.2 1.9e-19 69.5 0.2 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Mito_carr PF00153.27 CCH62214.1 - 2.3e-73 242.2 0.3 3.9e-25 87.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein MRG PF05712.13 CCH62215.1 - 8e-39 133.0 1.5 1.3e-38 132.3 1.5 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CCH62215.1 - 1.6e-07 31.1 0.4 5.2e-07 29.5 0.4 1.9 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.25 CCH62216.1 - 4.4e-20 72.2 0.0 6.9e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62216.1 - 1.3e-10 41.0 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH62216.1 - 2e-05 23.5 1.9 2.2e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase KHA PF11834.8 CCH62216.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel HECT PF00632.25 CCH62217.1 - 6.2e-96 321.5 0.0 8.3e-96 321.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CCH62217.1 - 4.3e-34 116.3 22.8 4.4e-12 45.9 1.3 4.2 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CCH62217.1 - 2e-19 69.7 0.2 5.6e-19 68.3 0.2 1.8 1 0 0 1 1 1 1 C2 domain Raftlin PF15250.6 CCH62217.1 - 0.06 12.1 4.1 0.11 11.2 4.1 1.4 1 0 0 1 1 1 0 Raftlin GalKase_gal_bdg PF10509.9 CCH62218.1 - 2.4e-20 71.8 0.0 6.8e-20 70.4 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CCH62218.1 - 2.8e-17 62.7 0.2 6.1e-17 61.6 0.2 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCH62218.1 - 1.8e-12 47.5 0.0 4.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal FRB_dom PF08771.11 CCH62218.1 - 0.035 14.5 0.6 0.11 13.0 0.6 1.8 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain MRP-S23 PF10484.9 CCH62218.1 - 1.6 9.0 3.8 18 5.6 2.1 2.7 2 1 0 2 2 2 0 Mitochondrial ribosomal protein S23 ABC2_membrane PF01061.24 CCH62219.1 - 1.3e-66 224.0 61.0 5.3e-39 133.8 14.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCH62219.1 - 3.4e-37 128.0 0.0 9.9e-19 68.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCH62219.1 - 4.4e-36 122.6 7.8 1.8e-30 104.7 0.0 4.3 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CCH62219.1 - 4.3e-12 45.8 3.3 4.3e-12 45.8 3.3 3.0 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CCH62219.1 - 1e-06 29.3 0.6 2.8e-06 27.8 0.6 1.9 1 1 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCH62219.1 - 4.4e-06 26.7 0.0 0.0005 20.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CCH62219.1 - 3.5e-05 24.3 0.0 0.0029 18.0 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain SMC_N PF02463.19 CCH62219.1 - 0.00011 21.8 0.2 0.36 10.2 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCH62219.1 - 0.00084 19.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CCH62219.1 - 0.0013 19.0 0.1 0.0088 16.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CCH62219.1 - 0.0016 19.0 0.0 0.006 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CCH62219.1 - 0.0026 17.8 0.1 0.13 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CCH62219.1 - 0.0051 16.5 0.2 0.092 12.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 CCH62219.1 - 0.0093 16.3 0.2 5.1 7.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase cobW PF02492.19 CCH62219.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TrpP PF17099.5 CCH62219.1 - 0.021 14.6 0.8 4.8 6.9 0.3 2.6 2 0 0 2 2 2 0 Tryptophan transporter TrpP AAA_25 PF13481.6 CCH62219.1 - 0.03 13.9 0.2 0.12 11.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CCH62219.1 - 0.052 13.3 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CCH62219.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CCH62219.1 - 0.14 11.9 0.1 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCH62219.1 - 0.17 11.8 0.3 0.59 10.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 CCH62219.1 - 0.19 11.7 0.3 0.88 9.6 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Transp_cyt_pur PF02133.15 CCH62220.1 - 5.8e-172 572.4 43.9 6.8e-172 572.2 43.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAYSvFN PF10260.9 CCH62220.1 - 0.035 14.0 0.4 0.035 14.0 0.4 3.8 3 1 1 4 4 4 0 Uncharacterized conserved domain (SAYSvFN) Chitin_synth_1 PF01644.17 CCH62221.1 - 3e-67 225.6 0.1 4.8e-67 225.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CCH62221.1 - 2.6e-22 78.6 0.1 6.1e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CCH62221.1 - 2e-20 73.0 9.5 3.6e-17 62.2 0.0 3.0 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CCH62221.1 - 1.1e-07 32.0 1.3 1.1e-07 32.0 1.3 2.2 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCH62221.1 - 0.0001 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 KIX PF02172.16 CCH62221.1 - 0.018 15.3 0.3 0.04 14.2 0.3 1.5 1 0 0 1 1 1 0 KIX domain DUF5337 PF17272.2 CCH62221.1 - 0.37 10.6 7.8 1 9.3 1.4 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) SCO1-SenC PF02630.14 CCH62222.1 - 2.8e-44 150.3 0.0 4.1e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Gram_pos_anchor PF00746.21 CCH62222.1 - 0.12 12.3 0.2 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif YchF-GTPase_C PF06071.13 CCH62223.1 - 4e-37 126.3 0.2 1.2e-36 124.7 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCH62223.1 - 7.6e-17 61.4 0.0 1.9e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCH62223.1 - 0.00033 20.7 0.0 0.00082 19.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCH62223.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B BetaGal_dom3 PF13363.6 CCH62223.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Cupin_2 PF07883.11 CCH62223.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain CSG2 PF16965.5 CCH62224.1 - 4.4e-165 549.5 4.6 5e-165 549.3 4.6 1.0 1 0 0 1 1 1 1 Ceramide synthase regulator CDP-OH_P_transf PF01066.21 CCH62224.1 - 0.56 11.0 0.1 0.56 11.0 0.1 3.5 3 2 0 3 3 3 0 CDP-alcohol phosphatidyltransferase ADH_zinc_N PF00107.26 CCH62225.1 - 1.6e-09 37.8 0.0 2.8e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF5614 PF18474.1 CCH62225.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5614) CTP_transf_1 PF01148.20 CCH62226.1 - 5.5e-74 249.3 21.7 7.7e-74 248.8 21.7 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family SET PF00856.28 CCH62227.1 - 2.6e-11 44.2 0.0 2.9e-07 31.0 0.0 2.7 1 1 0 2 2 2 2 SET domain zf-CCHC PF00098.23 CCH62227.1 - 0.14 12.3 1.7 0.28 11.3 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle PNISR PF15996.5 CCH62227.1 - 2.5 8.3 7.0 4 7.7 0.2 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Ribosomal_L4 PF00573.22 CCH62228.1 - 4e-44 150.6 1.3 7.3e-44 149.8 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CCH62228.1 - 6.5e-31 106.2 1.4 7.7e-30 102.8 0.7 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PrmA PF06325.13 CCH62229.1 - 1.6e-12 47.4 0.0 2.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CCH62229.1 - 1.2e-11 45.1 0.0 4.1e-11 43.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH62229.1 - 7.4e-11 42.1 0.0 2e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCH62229.1 - 1.5e-08 35.2 0.0 5.2e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCH62229.1 - 5.3e-08 32.2 0.0 6.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 CCH62229.1 - 1.2e-07 31.7 0.0 1.7e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCH62229.1 - 1.5e-05 24.6 0.1 3.1e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CCH62229.1 - 1.6e-05 24.9 0.1 2.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CCH62229.1 - 2.8e-05 23.5 0.1 3.8e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 CCH62229.1 - 0.00014 21.6 0.2 0.00024 20.9 0.2 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CCH62229.1 - 0.00047 20.9 0.1 0.0024 18.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 CCH62229.1 - 0.0015 17.9 0.1 0.003 16.9 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain FtsJ PF01728.19 CCH62229.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 CCH62229.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CCH62229.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 CCH62229.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Met_10 PF02475.16 CCH62229.1 - 0.036 13.8 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 CCH62229.1 - 0.085 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.13 CCH62229.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 PRMT5 PF05185.16 CCH62229.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 CCH62229.1 - 0.16 13.0 0.0 0.28 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CCH62229.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Sld5 PF05916.11 CCH62230.1 - 3.4e-09 37.1 0.0 5.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Occludin_ELL PF07303.13 CCH62230.1 - 0.032 14.9 1.1 0.032 14.9 1.1 2.1 3 0 0 3 3 3 0 Occludin homology domain DUF3016 PF11454.8 CCH62230.1 - 0.14 12.0 0.5 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) Peptidase_M24_C PF16188.5 CCH62230.1 - 0.85 9.7 3.7 13 6.0 0.1 3.2 2 2 1 3 3 3 0 C-terminal region of peptidase_M24 DASH_Dad3 PF08656.10 CCH62230.1 - 0.86 9.7 0.0 0.86 9.7 0.0 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad3 Wap1 PF16997.5 CCH62231.1 - 8.7e-128 426.7 38.1 8.7e-128 426.7 38.1 1.7 2 0 0 2 2 2 1 Wap1 domain VraX PF17412.2 CCH62231.1 - 0.0051 16.4 4.0 1.3 8.7 0.3 3.4 2 0 0 2 2 2 2 Family of unknown function PNP_phzG_C PF10590.9 CCH62232.1 - 5.7e-20 71.1 2.8 1.2e-19 70.1 2.8 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CCH62232.1 - 5.6e-12 45.7 0.0 7.7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CRCB PF02537.15 CCH62233.1 - 3.7e-29 100.9 11.5 5.5e-17 61.9 1.4 2.5 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) ATP-synt PF00231.19 CCH62234.1 - 3.6e-73 246.7 7.4 4.1e-73 246.5 7.4 1.0 1 0 0 1 1 1 1 ATP synthase AMP-binding PF00501.28 CCH62235.1 - 2.7e-58 197.6 0.0 3.2e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCH62235.1 - 4.9e-05 24.2 0.0 9.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Renin_r PF07850.14 CCH62235.1 - 0.12 13.0 0.1 0.35 11.5 0.0 1.8 2 0 0 2 2 2 0 Renin receptor-like protein GCV_T PF01571.21 CCH62236.1 - 3.8e-83 278.8 0.0 4.6e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CCH62236.1 - 3.6e-12 46.0 0.0 1e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain pXO2-72 PF17443.2 CCH62236.1 - 0.06 13.6 0.0 0.53 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 DUF3417 PF11897.8 CCH62236.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) YtzH PF14165.6 CCH62237.1 - 1.3 9.5 7.6 3.3 8.2 0.3 3.3 2 1 0 2 2 2 0 YtzH-like protein Atg31 PF09795.9 CCH62238.1 - 4.6e-47 159.9 10.3 5.3e-47 159.7 10.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 IpaB_EvcA PF03278.13 CCH62238.1 - 0.0049 16.6 1.2 0.0084 15.8 1.2 1.4 1 0 0 1 1 1 1 IpaB/EvcA family tRNA-synt_2b PF00587.25 CCH62239.1 - 1.9e-32 112.7 0.0 2.9e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CCH62239.1 - 2e-20 73.0 8.9 2e-20 73.0 8.9 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain IL22 PF14565.6 CCH62240.1 - 0.43 10.8 3.9 11 6.2 0.2 3.3 3 0 0 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Ribosomal_S17_N PF16205.5 CCH62241.1 - 1.2e-32 112.0 1.2 2.4e-32 111.1 1.2 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CCH62241.1 - 4.6e-27 93.9 3.2 4.6e-27 93.9 3.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 dsrm PF00035.26 CCH62241.1 - 3.9 8.2 6.2 48 4.8 2.1 3.1 2 1 0 2 2 2 0 Double-stranded RNA binding motif Myb_DNA-binding PF00249.31 CCH62242.1 - 1.9e-20 72.8 22.8 5.7e-12 45.6 1.5 4.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH62242.1 - 2.9e-17 62.6 16.0 1.7e-13 50.6 3.1 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CCH62242.1 - 0.25 11.6 1.8 0.9 9.8 0.2 2.6 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Peptidase_M2 PF01401.18 CCH62243.1 - 0.0042 15.8 0.6 0.011 14.5 0.6 1.6 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF1752 PF08550.10 CCH62244.1 - 8.6e-12 44.7 3.6 2.2e-11 43.4 3.6 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF5428 PF17493.2 CCH62244.1 - 0.098 13.1 0.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5428) WD40 PF00400.32 CCH62245.1 - 7.3e-09 36.1 0.5 0.022 15.6 0.4 4.3 3 0 0 3 3 3 3 WD domain, G-beta repeat PAP1 PF08601.10 CCH62245.1 - 2.8 7.6 7.5 5 6.8 7.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 CX9C PF16860.5 CCH62246.1 - 4e-16 58.7 16.7 2e-12 46.9 3.5 2.6 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 CCH62246.1 - 0.0021 18.2 10.3 0.29 11.4 5.5 3.4 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 CCH62246.1 - 0.0051 17.1 11.2 0.012 15.9 6.7 2.3 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 CCH62246.1 - 0.0093 16.0 9.6 0.015 15.3 2.1 2.7 1 1 2 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like SHE3 PF17078.5 CCH62246.1 - 0.033 13.9 0.9 0.041 13.6 0.9 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 COX6B PF02297.17 CCH62246.1 - 0.092 13.0 11.2 0.4 10.9 7.8 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb A1_Propeptide PF07966.12 CCH62246.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 A1 Propeptide OS-D PF03392.13 CCH62246.1 - 0.14 12.3 11.4 0.12 12.5 1.2 2.2 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D CHCH PF06747.13 CCH62246.1 - 0.2 11.8 11.9 0.73 10.0 2.2 2.9 2 1 0 2 2 2 0 CHCH domain GCK PF07802.11 CCH62246.1 - 0.25 11.8 5.0 3.5 8.1 1.7 2.7 1 1 2 3 3 3 0 GCK domain COX17 PF05051.13 CCH62246.1 - 0.54 10.7 7.7 0.39 11.1 1.2 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.13 CCH62246.1 - 2.5 7.9 9.9 24 4.7 2.3 3.2 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) FMN_red PF03358.15 CCH62247.1 - 7.7e-08 32.2 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CCH62247.1 - 5.2e-05 23.0 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CCH62247.1 - 0.0034 17.6 0.2 0.059 13.6 0.2 2.2 1 1 0 1 1 1 1 Flavodoxin Inositol_P PF00459.25 CCH62248.1 - 1.7e-52 178.7 0.0 3e-52 177.8 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2237 PF09996.9 CCH62248.1 - 0.066 13.2 0.0 1 9.4 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2237) AA_permease PF00324.21 CCH62249.1 - 3.8e-121 405.0 40.0 4.9e-121 404.7 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH62249.1 - 1.1e-29 103.5 40.0 1.4e-29 103.2 39.2 1.5 1 1 0 1 1 1 1 Amino acid permease Coprogen_oxidas PF01218.18 CCH62250.1 - 1.9e-127 424.1 0.0 2.1e-127 423.9 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Nuf2 PF03800.14 CCH62252.1 - 8.4e-26 90.8 2.9 8.4e-26 90.8 2.9 3.3 2 1 2 4 4 4 1 Nuf2 family DUF592 PF04574.13 CCH62253.1 - 1.5e-62 209.9 4.7 2.8e-62 209.0 4.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.17 CCH62253.1 - 3.5e-49 167.1 0.0 1.3e-48 165.3 0.0 1.9 2 0 0 2 2 2 1 Sir2 family Inv-AAD PF18785.1 CCH62254.1 - 2.4e-36 124.5 0.0 4.8e-36 123.5 0.0 1.5 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 CCH62254.1 - 1.9e-30 106.1 0.7 3.4e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 CCH62254.1 - 1.2e-16 60.4 0.0 2.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCH62254.1 - 6.4e-05 22.7 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Git3 PF11710.8 CCH62255.1 - 8.5e-72 241.2 14.3 8.5e-72 241.2 14.3 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 CCH62255.1 - 3.3e-31 107.2 1.3 3.3e-31 107.2 1.3 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Rhabdo_ncap PF00945.18 CCH62255.1 - 0.009 14.9 1.2 0.009 14.9 1.2 1.8 2 0 0 2 2 2 1 Rhabdovirus nucleocapsid protein 7tm_1 PF00001.21 CCH62255.1 - 0.026 13.9 0.5 0.13 11.6 0.5 2.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PBP1_TM PF14812.6 CCH62255.1 - 0.026 14.9 0.6 0.026 14.9 0.6 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR19-TM PF15176.6 CCH62255.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.7 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain CENP-B_dimeris PF09026.10 CCH62255.1 - 6.8 7.1 12.0 4 7.9 2.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SNF2_N PF00176.23 CCH62256.1 - 5.5e-62 209.5 0.0 8.2e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH62256.1 - 9e-16 58.2 0.0 2.6e-14 53.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH62256.1 - 3.4e-10 40.2 0.3 9.7e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCH62256.1 - 4.5e-07 29.3 3.8 3.7e-06 26.3 3.8 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CCH62256.1 - 3.2e-06 27.0 0.0 7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.9 CCH62256.1 - 0.016 15.5 0.1 0.081 13.3 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) bVLRF1 PF18826.1 CCH62257.1 - 3.1e-58 195.9 0.2 6.8e-58 194.8 0.2 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 CCH62257.1 - 0.011 16.3 0.1 0.028 15.0 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.7 CCH62257.1 - 0.018 15.4 0.3 0.049 14.0 0.3 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF678 PF05077.12 CCH62257.1 - 0.076 13.1 0.5 0.29 11.3 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Ank PF00023.30 CCH62257.1 - 0.14 12.6 0.1 0.31 11.6 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat DUF3744 PF12558.8 CCH62257.1 - 3.5 8.5 8.1 43 5.0 0.6 4.2 3 0 0 3 3 3 0 ATP-binding cassette cobalt transporter URO-D PF01208.17 CCH62258.1 - 9.6e-128 426.2 0.0 1.1e-127 426.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.17 CCH62259.1 - 2e-36 125.5 0.1 5.4e-36 124.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CCH62259.1 - 3.6e-05 23.6 0.0 7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CCH62259.1 - 0.00044 19.4 0.0 0.0024 16.9 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase DUF4451 PF14616.6 CCH62260.1 - 0.00028 21.1 3.8 0.0047 17.1 3.8 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) zf-C2H2 PF00096.26 CCH62261.1 - 1.2e-07 31.8 14.3 0.00014 22.1 5.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH62261.1 - 5.5e-05 23.7 11.7 0.033 15.0 3.7 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCH62261.1 - 0.0014 19.0 1.3 0.0014 19.0 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CCH62261.1 - 0.0014 19.0 0.9 0.0014 19.0 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCH62261.1 - 0.78 10.1 7.7 0.12 12.6 1.1 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Dfp1_Him1_M PF08630.10 CCH62262.1 - 1.6e-40 138.2 1.0 1.6e-40 138.2 1.0 3.8 4 0 0 4 4 4 1 Dfp1/Him1, central region zf-DBF PF07535.12 CCH62262.1 - 1.2e-19 70.1 1.1 2.4e-19 69.2 1.1 1.5 1 0 0 1 1 1 1 DBF zinc finger SLM4 PF16818.5 CCH62263.1 - 1.2e-45 155.3 11.6 1.8e-44 151.6 11.6 2.0 1 1 0 1 1 1 1 Protein SLM4 AlgF PF11182.8 CCH62263.1 - 0.0093 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Alginate O-acetyl transferase AlgF DUF4062 PF13271.6 CCH62263.1 - 0.069 13.5 0.0 0.18 12.2 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4062) UQ_con PF00179.26 CCH62264.1 - 2.6e-43 147.0 0.1 3.9e-43 146.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BUD22 PF09073.10 CCH62264.1 - 6.3 6.0 18.8 8.1 5.7 18.8 1.1 1 0 0 1 1 1 0 BUD22 Type2_restr_D3 PF16902.5 CCH62265.1 - 0.61 10.0 3.3 16 5.5 0.0 4.0 3 0 0 3 3 3 0 Type-2 restriction enzyme D3 domain ANAPC5 PF12862.7 CCH62265.1 - 1.4 9.0 6.5 0.4 10.8 0.4 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 AAA PF00004.29 CCH62266.1 - 9e-51 171.8 0.1 1.6e-38 132.1 0.0 2.7 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 CCH62266.1 - 2.1e-11 43.4 1.0 1.9e-10 40.3 0.2 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 CCH62266.1 - 1.9e-10 40.4 0.0 6e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CCH62266.1 - 4.5e-09 36.7 1.0 0.00023 21.5 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCH62266.1 - 2.3e-08 34.6 0.1 0.0083 16.5 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain CDC48_N PF02359.18 CCH62266.1 - 4.4e-08 33.2 0.0 2.6e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.13 CCH62266.1 - 1.3e-07 31.2 0.4 0.013 14.7 0.0 2.7 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_5 PF07728.14 CCH62266.1 - 2.9e-06 27.3 0.1 0.0042 17.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCH62266.1 - 6.6e-06 26.0 0.4 0.067 12.9 0.1 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CCH62266.1 - 6.9e-06 25.6 0.1 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 CCH62266.1 - 8.3e-06 26.0 0.0 0.0011 19.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CCH62266.1 - 9.5e-06 25.8 0.0 0.095 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 CCH62266.1 - 1.3e-05 24.7 0.0 0.017 14.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 CCH62266.1 - 1.7e-05 24.6 0.3 0.087 12.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CCH62266.1 - 2e-05 25.1 0.9 0.047 14.2 0.2 2.8 2 1 0 2 2 2 2 ABC transporter RNA_helicase PF00910.22 CCH62266.1 - 3e-05 24.3 0.0 0.095 13.1 0.0 3.2 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.17 CCH62266.1 - 6.1e-05 22.8 0.0 0.21 11.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 CCH62266.1 - 0.00014 21.6 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ResIII PF04851.15 CCH62266.1 - 0.00014 21.9 0.0 0.44 10.5 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CCH62266.1 - 0.00019 21.5 0.0 0.6 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CCH62266.1 - 0.0002 21.3 1.1 0.93 9.4 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_23 PF13476.6 CCH62266.1 - 0.00021 21.9 1.7 0.27 11.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CCH62266.1 - 0.00028 21.4 0.0 0.27 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCH62266.1 - 0.00035 20.6 0.1 0.58 10.2 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 CCH62266.1 - 0.00042 20.2 0.0 0.78 9.5 0.0 3.3 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_7 PF12775.7 CCH62266.1 - 0.00043 19.8 0.0 0.078 12.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 CCH62266.1 - 0.00054 19.2 0.3 0.45 9.6 0.0 2.7 3 0 0 3 3 2 2 NB-ARC domain TniB PF05621.11 CCH62266.1 - 0.00054 19.4 1.7 2.9 7.2 0.0 4.0 3 1 0 3 3 3 2 Bacterial TniB protein ATPase_2 PF01637.18 CCH62266.1 - 0.00058 19.9 0.5 1.2 9.0 0.0 3.3 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CCH62266.1 - 0.002 17.9 0.2 0.45 10.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 CCH62266.1 - 0.0044 16.4 1.2 0.33 10.3 0.1 2.9 3 0 0 3 3 3 1 KaiC AAA_30 PF13604.6 CCH62266.1 - 0.0053 16.5 0.0 0.83 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CCH62266.1 - 0.0053 16.0 0.1 0.37 10.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 CCH62266.1 - 0.0077 16.0 1.1 0.55 10.0 0.0 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 CCH62266.1 - 0.018 15.3 0.1 1.1 9.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_3 PF07726.11 CCH62266.1 - 0.021 14.7 0.0 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CCH62266.1 - 0.023 15.0 0.0 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CCH62266.1 - 0.024 14.6 0.1 7.2 6.5 0.0 3.0 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 CCH62266.1 - 0.038 13.6 0.7 4.8 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CCH62266.1 - 0.042 12.9 0.0 5.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Vps4_C PF09336.10 CCH62266.1 - 0.055 13.5 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Cytidylate_kin PF02224.18 CCH62266.1 - 0.08 12.7 0.1 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 CCH62266.1 - 0.12 11.6 0.1 4.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin IPT PF01745.16 CCH62266.1 - 0.13 11.6 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase cobW PF02492.19 CCH62266.1 - 0.39 10.3 2.1 40 3.7 0.1 3.3 2 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TEA PF01285.18 CCH62268.1 - 2.5e-22 78.7 0.2 5e-22 77.8 0.2 1.5 1 0 0 1 1 1 1 TEA/ATTS domain Ribosomal_60s PF00428.19 CCH62268.1 - 0.02 15.5 0.8 0.02 15.5 0.8 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sec62 PF03839.16 CCH62269.1 - 6.3 6.3 14.0 2.8 7.4 11.8 1.5 1 1 0 1 1 1 0 Translocation protein Sec62 LSM PF01423.22 CCH62270.1 - 6.7e-18 64.2 1.4 7.3e-18 64.0 1.4 1.0 1 0 0 1 1 1 1 LSM domain SelP_N PF04592.14 CCH62271.1 - 5 6.4 17.5 0.46 9.8 10.8 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF3835 PF12927.7 CCH62272.1 - 3.6e-17 63.0 0.1 3.6e-17 63.0 0.1 7.3 4 1 1 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin PF02996.17 CCH62272.1 - 3.6e-07 30.1 1.8 3.6e-07 30.1 1.8 4.4 5 1 0 5 5 5 1 Prefoldin subunit RasGAP_C PF03836.15 CCH62272.1 - 0.02 15.0 0.1 0.02 15.0 0.1 4.6 4 0 0 4 4 4 0 RasGAP C-terminus DUF3035 PF11233.8 CCH62272.1 - 1.1 9.5 7.5 6.2 7.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3035) MRP-S24 PF14955.6 CCH62272.1 - 9.9 6.1 8.3 11 6.0 0.5 3.3 2 1 1 3 3 3 0 Mitochondrial ribosome subunit S24 EPL1 PF10513.9 CCH62273.1 - 1.5e-19 70.9 6.4 1.5e-19 70.9 6.4 5.1 3 2 1 4 4 4 1 Enhancer of polycomb-like PGAP1 PF07819.13 CCH62274.1 - 3.7e-93 311.5 0.0 5.9e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CCH62274.1 - 0.00034 21.3 0.0 0.00061 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CCH62274.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 CCH62274.1 - 0.0024 17.5 0.0 0.0063 16.2 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 CCH62274.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 CCH62274.1 - 0.017 14.4 0.1 3 7.1 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 CCH62274.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CCH62274.1 - 0.072 13.0 0.0 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.8 CCH62274.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 CCH62274.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CCH62274.1 - 0.21 11.4 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold RabGAP-TBC PF00566.18 CCH62275.1 - 4.1e-16 59.3 10.7 4.1e-16 59.3 10.7 2.7 3 2 0 3 3 3 1 Rab-GTPase-TBC domain SRI PF08236.11 CCH62275.1 - 0.023 14.9 5.9 1.6 9.0 0.1 3.9 4 0 0 4 4 4 0 SRI (Set2 Rpb1 interacting) domain WD40 PF00400.32 CCH62276.1 - 2.9e-05 24.7 2.2 56 4.8 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat SHMT PF00464.19 CCH62277.1 - 7.3e-208 690.0 0.0 8.5e-208 689.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 CCH62277.1 - 9.2e-09 34.9 0.0 1.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCH62277.1 - 0.00012 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCH62277.1 - 0.00029 20.2 0.0 0.00065 19.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CCH62278.1 - 5.8e-24 84.7 0.0 8e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 CCH62278.1 - 0.2 11.7 0.0 1.4 9.0 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain bZIP_2 PF07716.15 CCH62279.1 - 2.7e-05 24.1 6.9 6.9e-05 22.8 6.9 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CCH62279.1 - 3.8e-05 23.7 3.5 8.4e-05 22.6 3.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor RNase_T PF00929.24 CCH62280.1 - 8.2e-25 88.3 0.0 1.3e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.25 CCH62281.1 - 9.3e-60 202.2 3.2 9.6e-38 130.0 0.1 4.0 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62281.1 - 4.1e-27 95.1 0.1 9.3e-22 77.5 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 CCH62281.1 - 1.7e-05 24.9 0.7 4.1e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain Kinase-like PF14531.6 CCH62281.1 - 0.00021 20.7 0.0 0.028 13.8 0.0 2.6 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CCH62281.1 - 0.00095 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCH62281.1 - 0.052 13.5 0.1 0.85 9.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family tRNA_synthFbeta PF17759.1 CCH62282.1 - 8.3e-42 143.0 0.0 1.3e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CCH62282.1 - 6.5e-30 103.2 1.3 2.5e-28 98.1 0.3 2.5 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CCH62282.1 - 6.6e-29 100.8 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CCH62282.1 - 2.7e-16 59.6 0.0 5.3e-15 55.5 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 CCH62282.1 - 0.015 14.8 0.0 0.13 11.8 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) Ribosomal_L22e PF01776.17 CCH62283.1 - 1.3e-39 134.9 0.9 1.5e-39 134.7 0.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mob1_phocein PF03637.17 CCH62284.1 - 6.9e-65 218.2 1.6 6.9e-65 218.2 1.6 1.9 2 0 0 2 2 2 1 Mob1/phocein family PAT1 PF09770.9 CCH62284.1 - 5 5.3 19.9 6.4 4.9 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 CCH62284.1 - 5.2 7.0 24.8 7 6.5 24.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 CCH62284.1 - 6 6.5 9.2 10 5.7 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RNA_pol PF00940.19 CCH62285.1 - 3.9e-181 602.4 0.0 5.9e-181 601.8 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CCH62285.1 - 1.4e-96 323.8 1.1 2.5e-96 323.0 1.1 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF3027 PF11228.8 CCH62285.1 - 0.12 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) Tubulin PF00091.25 CCH62286.1 - 1.5e-69 234.2 0.0 3.2e-69 233.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCH62286.1 - 2.1e-42 144.3 0.0 3.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCH62286.1 - 4.9e-05 23.6 0.0 0.00011 22.5 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CCH62286.1 - 0.00071 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CCH62286.1 - 0.0045 16.2 0.0 0.0098 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin like MutS_V PF00488.21 CCH62287.1 - 1.6e-50 171.8 0.1 4.9e-50 170.2 0.1 1.9 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCH62287.1 - 2.4e-24 86.6 13.5 2.4e-24 86.6 13.5 3.3 3 1 0 3 3 3 1 MutS domain III MutS_II PF05188.17 CCH62287.1 - 5.8e-13 49.3 0.1 3.3e-12 46.9 0.1 2.4 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CCH62287.1 - 2.5e-12 47.0 1.2 2.5e-12 47.0 1.2 4.4 4 1 0 4 4 4 1 MutS family domain IV Caprin-1_C PF12287.8 CCH62287.1 - 0.23 11.6 2.4 0.4 10.8 2.4 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Toprim PF01751.22 CCH62287.1 - 0.23 11.7 1.5 0.85 9.9 0.0 2.8 3 0 0 3 3 3 0 Toprim domain BLM10_mid PF16507.5 CCH62288.1 - 2e-152 508.5 17.8 2e-152 508.5 17.8 1.9 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 CCH62288.1 - 4e-31 107.1 0.8 9.5e-31 105.9 0.1 2.1 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 CCH62288.1 - 4.5e-25 87.4 0.0 3e-24 84.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 CCH62288.1 - 0.029 14.6 0.0 20 5.8 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat SMC_N PF02463.19 CCH62289.1 - 7.6e-58 195.5 41.2 1.9e-34 119.0 5.4 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCH62289.1 - 1.6e-24 86.4 2.0 2.7e-24 85.7 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCH62289.1 - 7.2e-11 42.4 4.8 1.6e-06 28.2 0.1 5.8 2 2 2 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCH62289.1 - 4.1e-08 32.8 0.1 1.1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH62289.1 - 0.0063 16.8 2.5 14 6.0 0.0 4.6 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 CCH62289.1 - 0.054 14.0 0.0 0.054 14.0 0.0 6.5 4 2 0 4 4 4 0 ABC transporter SbcCD_C PF13558.6 CCH62289.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 CCH62289.1 - 0.06 12.9 0.0 0.06 12.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain WW PF00397.26 CCH62290.1 - 2.2e-11 43.6 0.9 4e-11 42.8 0.9 1.5 1 0 0 1 1 1 1 WW domain TFIIA PF03153.13 CCH62290.1 - 0.62 10.0 18.5 0.7 9.8 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CCH62290.1 - 2.8 6.1 16.6 3.6 5.7 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFR_dimer PF04253.15 CCH62291.1 - 0.11 12.6 0.3 0.69 10.0 0.0 2.2 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Mito_carr PF00153.27 CCH62292.1 - 1.1e-70 233.7 4.2 7.3e-25 86.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.29 CCH62293.1 - 5e-28 96.7 11.7 1.9e-09 37.2 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCH62293.1 - 1.9e-07 30.8 5.4 0.084 12.7 0.4 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CCH62293.1 - 2.5e-05 24.1 0.8 3.7 7.5 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CCH62293.1 - 0.0001 22.3 3.1 0.23 11.6 0.1 3.8 3 0 0 3 3 3 2 NusA-like KH domain Mucin PF01456.17 CCH62293.1 - 0.18 11.8 9.9 0.33 10.9 9.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.13 CCH62293.1 - 1.2 7.4 8.2 1.8 6.8 8.2 1.1 1 0 0 1 1 1 0 Menin HMG_CoA_synt_C PF08540.10 CCH62294.1 - 6.8e-107 357.3 5.7 8.8e-107 356.9 5.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CCH62294.1 - 1.9e-95 317.6 0.5 3.2e-95 316.9 0.5 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Utp12 PF04003.12 CCH62295.1 - 0.012 15.9 0.2 0.061 13.6 0.2 2.2 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF1398 PF07166.11 CCH62295.1 - 2 8.5 6.9 1.5 8.9 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1398) COX14 PF14880.6 CCH62297.1 - 1.7e-16 59.8 0.3 2.2e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF1772 PF08592.11 CCH62297.1 - 0.0099 16.2 0.0 0.0099 16.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Torus PF16131.5 CCH62298.1 - 1.9e-05 25.3 0.4 0.14 12.9 0.0 2.3 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 CCH62298.1 - 0.0015 18.3 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CCH62298.1 - 0.0055 16.7 14.4 0.047 13.8 2.7 3.4 2 1 1 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 CCH62298.1 - 0.096 12.6 13.6 0.81 9.7 1.8 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CAP_N PF01213.19 CCH62298.1 - 0.5 9.8 2.7 0.65 9.4 2.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HiaBD2 PF15403.6 CCH62298.1 - 1.6 9.2 5.9 2.5 8.6 3.3 2.3 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) PI-PLC-X PF00388.19 CCH62299.1 - 4.7e-18 65.2 0.0 9e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L18A PF01775.17 CCH62299.1 - 0.0034 17.5 0.0 0.0064 16.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF3589 PF12141.8 CCH62300.1 - 4.6e-82 276.2 1.2 1.3e-51 175.8 0.0 3.0 3 0 0 3 3 3 2 Beta-mannosyltransferases Oxidored_FMN PF00724.20 CCH62301.1 - 2.4e-121 405.2 0.0 2.8e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCH62301.1 - 0.0042 17.3 0.1 3.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5442) Mannosyl_trans3 PF11051.8 CCH62302.1 - 2.1e-73 247.0 3.0 3.1e-73 246.5 3.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3119 PF11317.8 CCH62302.1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) Rotamase_2 PF13145.6 CCH62304.1 - 0.0022 18.8 1.5 0.0029 18.5 1.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain TipE PF16972.5 CCH62304.1 - 1 8.5 8.3 1.2 8.3 8.3 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Folliculin PF11704.8 CCH62304.1 - 3.1 7.6 7.3 5.5 6.8 7.3 1.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport zf-C2H2_9 PF16293.5 CCH62305.1 - 0.064 13.1 0.1 0.32 10.9 0.1 2.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) DUF3324 PF11797.8 CCH62305.1 - 0.7 9.9 5.4 0.22 11.5 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function C-terminal (DUF3324) Mannosyl_trans3 PF11051.8 CCH62306.1 - 7.9e-69 232.1 0.1 1.1e-68 231.5 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CshA_NR2 PF18651.1 CCH62306.1 - 0.017 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Surface adhesin CshA non-repetitive domain 2 Pam16 PF03656.13 CCH62307.1 - 0.00051 20.1 0.0 0.00079 19.4 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CCH62307.1 - 0.014 15.5 0.2 0.035 14.2 0.2 1.6 1 1 0 1 1 1 0 DnaJ domain Pesticin PF16754.5 CCH62307.1 - 0.14 12.1 0.3 2.3 8.2 0.0 2.1 1 1 1 2 2 2 0 Bacterial toxin homologue of phage lysozyme, C-term DHHC PF01529.20 CCH62308.1 - 4.2e-35 120.8 15.2 4.2e-35 120.8 15.2 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase KH_6 PF15985.5 CCH62309.1 - 1.1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CCH62309.1 - 0.00037 20.4 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain E1_UFD PF09358.10 CCH62309.1 - 0.0015 19.2 0.0 0.0035 18.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain MOSP_C PF02722.15 CCH62309.1 - 0.077 12.7 0.0 2.3 7.9 0.0 2.1 1 1 0 2 2 2 0 Major Outer Sheath Protein C-terminal domain Syja_N PF02383.18 CCH62310.1 - 1.8e-75 254.2 0.2 1.8e-75 254.2 0.2 1.8 2 0 0 2 2 2 1 SacI homology domain HTH_CodY PF08222.11 CCH62310.1 - 0.025 14.1 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 CodY helix-turn-helix domain LCM PF04072.14 CCH62311.1 - 5e-25 88.6 0.0 8.1e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 CCH62311.1 - 7e-11 42.0 11.9 4.6e-08 32.9 0.1 4.8 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CCH62311.1 - 1.7e-09 37.2 4.3 0.00048 20.0 0.1 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CCH62311.1 - 4.8e-08 32.8 2.4 0.0038 17.2 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CCH62311.1 - 9.1e-08 32.1 6.7 0.0084 16.4 0.1 4.9 4 1 1 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CCH62311.1 - 0.0085 15.7 6.3 0.34 10.5 0.1 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 CCH62311.1 - 0.32 11.3 4.6 25 5.3 0.1 4.0 6 0 0 6 6 6 0 Galactose oxidase, central domain CDC50 PF03381.15 CCH62312.1 - 9.1e-85 284.6 2.3 9.1e-85 284.6 2.3 1.4 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Aminotran_3 PF00202.21 CCH62313.1 - 3e-122 408.2 0.0 3.7e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Na_Ca_ex PF01699.24 CCH62314.1 - 3.4e-19 69.3 36.0 1.2e-13 51.3 16.0 3.8 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 CCH62314.1 - 8.2e-10 39.2 1.7 8.2e-10 39.2 1.7 5.1 3 0 0 3 3 3 1 Inner membrane component domain IF4E PF01652.18 CCH62315.1 - 1.9e-52 177.3 1.7 2.2e-52 177.1 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Zn_ribbon_17 PF17120.5 CCH62316.1 - 1.2e-08 34.4 4.9 3e-08 33.2 4.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCH62316.1 - 1.6e-08 35.0 8.3 0.0013 19.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.6 CCH62316.1 - 7.1e-06 26.3 8.2 7.1e-06 26.3 8.2 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CCH62316.1 - 0.00083 19.6 11.0 0.0023 18.2 11.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCH62316.1 - 0.00088 19.1 8.6 0.0025 17.6 8.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH62316.1 - 0.0015 18.4 4.5 0.0015 18.4 4.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCH62316.1 - 0.0058 16.4 8.6 0.017 14.8 8.6 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CCH62316.1 - 0.12 12.4 7.6 0.28 11.3 7.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CCH62316.1 - 0.53 10.3 16.1 0.8 9.7 11.8 2.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CCH62316.1 - 0.69 10.0 5.9 2.4 8.2 5.9 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Sugar_tr PF00083.24 CCH62317.1 - 2e-113 379.7 26.3 2.2e-113 379.5 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH62317.1 - 5.3e-24 84.8 46.8 1.5e-23 83.3 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SelK_SelG PF10961.8 CCH62317.1 - 5.9 7.6 6.9 1.6 9.4 0.3 2.9 3 0 0 3 3 3 0 Selenoprotein SelK_SelG MFS_1 PF07690.16 CCH62318.1 - 2.7e-19 69.3 22.5 7.5e-12 44.8 0.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily HAD_2 PF13419.6 CCH62319.1 - 2.4e-06 27.8 0.0 4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCH62319.1 - 0.00046 20.2 0.0 0.00083 19.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CCH62319.1 - 0.0063 16.8 0.0 0.0098 16.2 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lipoprotein_1 PF00820.19 CCH62319.1 - 0.013 14.6 1.1 0.022 13.8 1.1 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein DNA_mis_repair PF01119.19 CCH62320.1 - 1.4e-13 50.5 0.4 3.1e-13 49.5 0.4 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCH62320.1 - 3.1e-08 33.5 0.0 8.2e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCH62320.1 - 0.0004 20.9 0.1 0.00091 19.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF108 PF01958.18 CCH62320.1 - 0.15 12.5 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF108 Mltc_N PF11873.8 CCH62321.1 - 0.017 14.8 0.1 0.05 13.3 0.1 1.7 1 0 0 1 1 1 0 Membrane-bound lytic murein transglycosylase C, N-terminal domain Bromodomain PF00439.25 CCH62322.1 - 0.00032 20.7 5.0 0.0025 17.8 5.0 2.5 1 1 0 1 1 1 1 Bromodomain Iron_permease PF04120.12 CCH62322.1 - 3.6 7.4 6.0 1.2 8.9 2.3 2.1 2 0 0 2 2 2 0 Low affinity iron permease HA2 PF04408.23 CCH62323.1 - 2.2e-24 85.8 0.0 2.2e-24 85.8 0.0 2.9 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCH62323.1 - 1.2e-13 51.4 0.4 3.5e-11 43.4 0.0 4.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCH62323.1 - 4.8e-10 39.7 0.0 1.3e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCH62323.1 - 1.9e-08 34.3 0.0 5.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH62323.1 - 2.2e-05 24.7 1.2 9.1e-05 22.7 0.0 2.4 2 1 1 3 3 3 1 AAA domain HTH_37 PF13744.6 CCH62323.1 - 0.0029 17.5 0.4 0.013 15.4 0.4 2.2 1 0 0 1 1 1 1 Helix-turn-helix domain ATPase PF06745.13 CCH62323.1 - 0.0049 16.3 1.1 0.011 15.1 0.1 2.2 2 1 0 2 2 2 1 KaiC AAA_19 PF13245.6 CCH62323.1 - 0.014 15.7 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCH62323.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 CCH62323.1 - 0.067 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 CCH62323.1 - 0.097 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4704 PF15787.5 CCH62323.1 - 0.15 11.3 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) MOZ_SAS PF01853.18 CCH62324.1 - 1.5e-56 190.9 1.3 2e-56 190.5 1.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCH62324.1 - 3.8e-09 36.0 4.0 1.1e-07 31.3 1.7 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCH62324.1 - 0.0091 16.4 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCH62324.1 - 0.056 13.7 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 CCH62325.1 - 1.2e-69 234.7 0.2 1.2e-69 234.7 0.2 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH62325.1 - 2.5e-12 47.1 0.0 1.5e-11 44.6 0.0 2.4 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 CCH62325.1 - 2.7e-12 46.4 0.0 6.1e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.6 CCH62325.1 - 4.8e-10 39.6 7.4 9.9e-10 38.6 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCH62325.1 - 1.6e-09 37.4 4.7 3e-09 36.6 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH62325.1 - 2.5e-07 30.5 7.6 5e-07 29.5 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH62325.1 - 3.2e-06 27.0 7.6 7.2e-06 25.9 7.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CCH62325.1 - 3.3e-06 27.0 6.3 7.4e-06 25.9 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCH62325.1 - 0.00029 20.6 7.8 0.00077 19.3 7.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH62325.1 - 0.00035 20.4 8.1 0.0033 17.2 8.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCH62325.1 - 0.00043 20.4 7.7 0.0011 19.1 7.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CCH62325.1 - 0.00054 20.2 5.0 0.0012 19.1 5.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CCH62325.1 - 0.0015 18.3 7.6 0.0035 17.1 7.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CCH62325.1 - 0.0022 18.0 2.1 0.0043 17.1 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF5601 PF18151.1 CCH62325.1 - 0.19 12.1 3.0 17 5.8 1.7 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) zf-Nse PF11789.8 CCH62325.1 - 1.2 9.0 3.8 5.6 6.9 3.8 2.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CCH62325.1 - 5.7 7.0 6.0 16 5.6 6.0 1.8 1 1 0 1 1 1 0 Double zinc ribbon MIF4G_like PF09088.11 CCH62326.1 - 4.3e-53 179.9 0.5 1.1e-52 178.6 0.5 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 CCH62326.1 - 1.4e-47 162.4 9.5 5.8e-46 157.1 6.5 2.7 2 1 0 2 2 2 1 MIF4G like Pkr1 PF08636.10 CCH62327.1 - 2.3e-20 72.5 5.1 2.8e-20 72.2 5.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 TMEM208_SND2 PF05620.11 CCH62327.1 - 0.0033 17.2 0.1 0.0042 16.9 0.1 1.1 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Halogen_Hydrol PF10112.9 CCH62327.1 - 0.012 15.6 0.3 0.014 15.4 0.3 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Wzy_C PF04932.15 CCH62327.1 - 0.031 13.9 0.3 0.037 13.7 0.3 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF2500 PF10694.9 CCH62327.1 - 0.041 14.4 0.1 0.041 14.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Sarcoglycan_2 PF05510.13 CCH62327.1 - 0.043 12.6 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF2207 PF09972.9 CCH62327.1 - 0.06 12.1 1.0 0.08 11.7 1.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AICARFT_IMPCHas PF01808.18 CCH62328.1 - 4.4e-90 302.1 0.0 1.5e-89 300.4 0.0 1.7 2 0 0 2 2 2 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCH62328.1 - 3.2e-22 78.5 0.9 6.7e-22 77.5 0.1 2.0 2 0 0 2 2 2 1 MGS-like domain Sdh_cyt PF01127.22 CCH62329.1 - 6.8e-18 64.8 0.3 9.1e-18 64.5 0.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit COX7B PF05392.11 CCH62329.1 - 0.55 9.9 3.9 0.82 9.4 0.1 2.7 3 0 0 3 3 3 0 Cytochrome C oxidase chain VIIB Pkinase PF00069.25 CCH62330.1 - 2.6e-65 220.4 0.1 4.2e-65 219.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62330.1 - 2.5e-27 95.8 0.3 3.5e-26 92.0 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH62330.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF5584 PF17822.1 CCH62330.1 - 0.051 13.0 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5584) DASH_Hsk3 PF08227.11 CCH62331.1 - 5.8e-08 33.0 5.3 1.3e-07 31.9 5.3 1.6 1 1 0 1 1 1 1 DASH complex subunit Hsk3 like ORF6C PF10552.9 CCH62331.1 - 0.026 14.6 0.2 0.032 14.3 0.2 1.1 1 0 0 1 1 1 0 ORF6C domain DUF4763 PF15960.5 CCH62331.1 - 0.048 13.0 1.0 0.058 12.7 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DASH_Dad3 PF08656.10 CCH62331.1 - 0.099 12.7 1.8 0.2 11.7 1.8 1.5 1 1 0 1 1 1 0 DASH complex subunit Dad3 Spc24 PF08286.11 CCH62332.1 - 1.6e-05 25.1 2.7 1.6e-05 25.1 2.7 2.8 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Met_synt_B12 PF02965.17 CCH62332.1 - 0.0011 18.5 4.6 0.0014 18.1 4.6 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain BLOC1_2 PF10046.9 CCH62332.1 - 0.067 13.5 9.9 0.065 13.5 7.9 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CCH62332.1 - 0.4 10.9 16.6 0.13 12.5 9.4 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family UPF0231 PF06062.11 CCH62332.1 - 0.56 10.5 7.7 0.24 11.7 4.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) NPV_P10 PF05531.12 CCH62332.1 - 0.83 10.2 16.3 1 9.8 7.6 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein ApoO PF09769.9 CCH62332.1 - 0.88 9.5 3.6 2.7 7.9 1.1 2.2 1 1 1 2 2 2 0 Apolipoprotein O Csm1_N PF18504.1 CCH62332.1 - 3.6 8.0 13.2 0.83 10.0 1.4 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain L31 PF09784.9 CCH62333.1 - 3.2e-42 143.1 0.9 3.8e-42 142.9 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Adaptin_N PF01602.20 CCH62334.1 - 5.6e-83 279.3 30.6 7.5e-83 278.9 30.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCH62334.1 - 8.7e-37 126.7 9.0 8.7e-37 126.7 9.0 4.8 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCH62334.1 - 9.7e-06 25.4 0.0 0.023 14.9 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 CCH62334.1 - 6.8e-05 23.2 0.0 0.00028 21.2 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats RTP1_C1 PF10363.9 CCH62334.1 - 0.0044 17.2 3.8 0.44 10.8 0.1 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 S10_plectin PF03501.15 CCH62335.1 - 0.008 16.2 0.3 0.023 14.7 0.3 1.8 1 0 0 1 1 1 1 Plectin/S10 domain NP1-WLL PF11733.8 CCH62335.1 - 0.093 12.5 1.6 0.15 11.8 1.6 1.3 1 0 0 1 1 1 0 Non-capsid protein NP1 Dapper PF15268.6 CCH62336.1 - 0.0051 15.7 10.1 0.0067 15.4 10.1 1.1 1 0 0 1 1 1 1 Dapper KH_1 PF00013.29 CCH62336.1 - 0.12 12.3 0.0 0.52 10.2 0.0 2.2 1 1 0 1 1 1 0 KH domain BLOC1_2 PF10046.9 CCH62337.1 - 2.2 8.6 8.0 0.3 11.4 0.1 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L5_C PF00673.21 CCH62338.1 - 4.4e-28 97.3 0.0 1.7e-27 95.4 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCH62338.1 - 1.3e-11 44.6 0.0 2.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Flavokinase PF01687.17 CCH62339.1 - 2.9e-25 88.7 0.0 4e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase DUF4250 PF14056.6 CCH62339.1 - 0.046 13.7 0.1 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Reticulon PF02453.17 CCH62340.1 - 0.001 19.1 7.9 0.0022 18.0 7.9 1.6 1 1 0 1 1 1 1 Reticulon Sel1 PF08238.12 CCH62341.1 - 3.7e-23 81.4 13.1 0.0038 17.9 0.0 8.4 8 1 0 8 8 8 6 Sel1 repeat TPR_6 PF13174.6 CCH62341.1 - 0.008 16.8 1.9 48 4.9 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCH62341.1 - 3.9 7.4 16.5 15 5.6 0.3 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP1_TIP1 PF00660.17 CCH62342.1 - 9.8e-27 92.9 0.2 9.8e-27 92.9 0.2 3.6 4 1 0 4 4 4 1 Seripauperin and TIP1 family Flocculin_t3 PF13928.6 CCH62342.1 - 0.00036 21.0 11.1 0.00036 21.0 11.1 11.4 4 3 5 10 10 10 6 Flocculin type 3 repeat DUF1385 PF07136.11 CCH62343.1 - 0.18 11.1 7.1 0.57 9.4 7.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1385) Zn_clus PF00172.18 CCH62344.1 - 2e-08 34.2 10.5 4.2e-08 33.2 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L10 PF00466.20 CCH62345.1 - 3.4e-05 23.9 0.0 6.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Fimbrillin_C PF15495.6 CCH62345.1 - 0.032 14.7 0.0 0.088 13.2 0.0 1.7 1 1 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal Methyltransf_4 PF02390.17 CCH62346.1 - 2.9e-61 205.9 0.0 5e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CCH62346.1 - 5.3e-06 27.1 0.0 0.00016 22.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.16 CCH62346.1 - 0.00017 20.8 0.1 0.00029 20.0 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.12 CCH62346.1 - 0.0012 19.5 0.1 0.0043 17.8 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCH62346.1 - 0.0013 18.5 0.0 0.0032 17.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCH62346.1 - 0.0014 18.2 0.0 0.0053 16.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CCH62346.1 - 0.0043 16.4 0.0 0.017 14.5 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CCH62346.1 - 0.016 15.8 0.0 1.5 9.5 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 CCH62346.1 - 0.13 11.8 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 Mito_carr PF00153.27 CCH62347.1 - 3.1e-34 116.8 1.5 4.7e-14 52.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SIR4_SID PF16991.5 CCH62348.1 - 3.1e-44 150.9 4.1 3.1e-44 150.9 4.1 12.8 8 2 6 15 15 15 1 Sir4 SID domain Phage_ABA_S PF18066.1 CCH62348.1 - 4.2 8.1 5.6 14 6.4 0.0 4.0 4 0 0 4 4 4 0 Phage ABA sandwich domain DUF4110 PF13422.6 CCH62349.1 - 7.9 6.6 10.8 1.4 9.0 0.1 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4110) VIT1 PF01988.19 CCH62350.1 - 1.2e-60 205.1 1.1 1.4e-60 204.9 1.1 1.1 1 0 0 1 1 1 1 VIT family PsbI PF02532.14 CCH62350.1 - 0.39 10.7 1.8 0.81 9.7 1.8 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) CRF1 PF10380.9 CCH62351.1 - 4.5e-35 120.4 4.9 4.5e-35 120.4 4.9 4.7 4 1 0 4 4 4 1 Transcription factor CRF1 PRKCSH-like PF12999.7 CCH62352.1 - 1.5e-38 132.3 5.3 4.9e-38 130.7 5.3 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CCH62352.1 - 4.5e-18 65.4 4.6 9.2e-18 64.4 0.5 3.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CCH62352.1 - 4.2e-06 27.7 0.2 1.7e-05 25.7 0.2 2.2 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein IFT20 PF14931.6 CCH62352.1 - 3.8 7.7 17.9 1.2 9.3 6.3 3.1 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 ABC_tran_CTD PF16326.5 CCH62352.1 - 7.6 6.9 11.0 1.3 9.3 5.9 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain ING PF12998.7 CCH62352.1 - 9.4 6.9 17.6 0.32 11.6 0.8 3.8 3 1 1 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Cyclin_N PF00134.23 CCH62354.1 - 0.02 14.6 0.3 0.046 13.5 0.3 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Septin PF00735.18 CCH62355.1 - 2.3e-69 233.8 5.1 3.2e-69 233.3 5.1 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 CCH62355.1 - 0.00013 22.1 0.1 0.00013 22.1 0.1 2.5 2 2 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CCH62355.1 - 0.00029 20.8 0.3 0.034 14.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CCH62355.1 - 0.00042 20.9 0.8 0.00091 19.8 0.0 1.9 3 0 0 3 3 2 1 ABC transporter AAA_33 PF13671.6 CCH62355.1 - 0.0024 18.1 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CCH62355.1 - 0.0046 17.0 1.4 0.021 14.9 0.6 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CCH62355.1 - 0.0064 16.5 0.7 0.034 14.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 CCH62355.1 - 0.0085 16.3 0.0 0.044 14.0 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CCH62355.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CCH62355.1 - 0.027 14.4 3.1 0.043 13.7 1.1 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Microtub_bd PF16796.5 CCH62355.1 - 0.037 14.0 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Microtubule binding AAA_29 PF13555.6 CCH62355.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CCH62355.1 - 0.043 14.2 0.0 0.27 11.6 0.0 2.4 2 1 1 3 3 3 0 RNA helicase AAA_24 PF13479.6 CCH62355.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH62355.1 - 0.071 13.7 0.1 0.071 13.7 0.1 2.1 2 1 1 3 3 2 0 AAA domain AAA_22 PF13401.6 CCH62355.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CCH62355.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rad9_Rad53_bind PF08605.10 CCH62356.1 - 1.7e-28 99.4 0.6 7e-28 97.4 0.6 2.2 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 CCH62356.1 - 1.1e-08 35.3 4.1 1.4e-08 35.0 1.2 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCH62356.1 - 3.2e-05 24.3 0.9 0.00025 21.4 0.9 2.6 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CCH62356.1 - 0.0001 22.1 0.7 0.00052 19.8 0.1 2.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain Tudor_3 PF18115.1 CCH62356.1 - 0.14 12.0 0.1 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain zf-C2H2 PF00096.26 CCH62357.1 - 4.3e-07 30.0 11.3 0.0039 17.5 3.7 3.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH62357.1 - 5e-06 26.7 10.1 3.6e-05 24.0 5.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH62357.1 - 0.0057 17.4 17.1 0.11 13.3 3.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 CCH62357.1 - 0.022 14.4 3.4 2.3 7.9 0.5 2.7 1 1 1 2 2 2 0 MYST family zinc finger domain zf-Di19 PF05605.12 CCH62357.1 - 0.042 14.1 1.3 0.095 13.0 1.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CCH62357.1 - 0.69 10.0 5.6 0.13 12.3 1.6 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger Aha1_N PF09229.11 CCH62358.1 - 1.8e-37 128.6 0.1 3.2e-37 127.8 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CCH62358.1 - 2e-06 28.1 0.0 3.4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein APC1_C PF18122.1 CCH62358.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF3439 PF11921.8 CCH62358.1 - 0.084 12.8 1.3 0.17 11.9 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Fungal_trans_2 PF11951.8 CCH62359.1 - 2.8e-13 49.4 0.2 2.8e-13 49.4 0.2 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH62359.1 - 7.6e-08 32.4 10.1 1.3e-07 31.6 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 CCH62360.1 - 4.9e-51 172.6 0.0 5.8e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH62360.1 - 6.4e-19 68.3 0.0 9.6e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH62360.1 - 4.6e-07 29.4 0.0 6.2e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Zn_clus PF00172.18 CCH62361.1 - 1.8e-08 34.4 9.5 3.2e-08 33.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RT_RNaseH_2 PF17919.1 CCH62362.1 - 2.7e-28 97.9 0.0 4.1e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCH62362.1 - 4.2e-20 72.0 0.0 7.6e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CCH62362.1 - 1.7e-19 70.2 0.0 3.9e-19 69.1 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_pol_viral_C PF00336.18 CCH62362.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Transp_cyt_pur PF02133.15 CCH62363.1 - 1.1e-72 245.3 38.1 1.1e-72 245.3 38.1 1.3 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 CCH62364.1 - 1.2e-29 103.4 25.2 1.2e-29 103.4 25.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCH62364.1 - 0.0006 18.8 28.4 0.00079 18.4 13.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CCH62364.1 - 0.00072 18.1 6.6 0.0011 17.5 6.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2754 PF10953.8 CCH62364.1 - 0.006 16.8 0.0 0.024 14.9 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2754) Rick_17kDa_Anti PF05433.15 CCH62364.1 - 0.054 13.4 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain YqhR PF11085.8 CCH62364.1 - 1.8 8.5 10.9 0.39 10.6 6.6 2.0 2 0 0 2 2 2 0 Conserved membrane protein YqhR Thi4 PF01946.17 CCH62365.1 - 4e-107 356.8 0.2 4.7e-107 356.6 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CCH62365.1 - 5.6e-05 22.9 2.2 7.3e-05 22.5 0.5 1.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH62365.1 - 0.00013 22.1 0.3 0.00067 19.8 0.3 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CCH62365.1 - 0.00035 20.6 0.1 0.0016 18.5 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CCH62365.1 - 0.00036 19.7 0.7 0.0056 15.8 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 CCH62365.1 - 0.00071 18.7 0.4 0.0011 18.1 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CCH62365.1 - 0.0019 17.5 0.4 0.0062 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCH62365.1 - 0.004 16.6 0.1 0.006 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCH62365.1 - 0.021 13.5 0.6 0.035 12.8 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CCH62365.1 - 0.034 13.4 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Coq4 PF05019.13 CCH62366.1 - 4.4e-90 300.8 0.0 5.4e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SMI1_KNR4 PF09346.10 CCH62366.1 - 0.034 14.5 0.1 0.07 13.5 0.1 1.5 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Rogdi_lz PF10259.9 CCH62367.1 - 1.1e-53 182.4 0.0 1.3e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DASH_Spc19 PF08287.11 CCH62368.1 - 1e-23 83.9 14.1 1.2e-23 83.8 14.1 1.0 1 0 0 1 1 1 1 Spc19 FapA PF03961.13 CCH62368.1 - 0.52 8.8 7.5 0.67 8.5 7.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CHD5 PF04420.14 CCH62368.1 - 0.87 9.4 8.0 0.58 10.0 2.8 2.2 1 1 1 2 2 2 0 CHD5-like protein APG6_N PF17675.1 CCH62368.1 - 4.2 7.9 15.8 66 4.0 15.8 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region FHA PF00498.26 CCH62369.1 - 7.2e-15 55.1 2.3 2.3e-14 53.5 1.0 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CCH62369.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain XRN1_DBM PF18245.1 CCH62369.1 - 0.11 12.4 1.2 0.25 11.4 1.2 1.5 1 0 0 1 1 1 0 5-3 exonuclease XRN1 DCP1-binding motif HR1 PF02185.16 CCH62369.1 - 0.45 10.7 7.7 1.9 8.6 1.2 2.6 2 1 0 2 2 2 0 Hr1 repeat Cnn_1N PF07989.11 CCH62369.1 - 0.55 10.4 8.5 0.093 12.9 2.6 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Uds1 PF15456.6 CCH62369.1 - 1.2 9.3 4.4 0.81 9.9 2.3 1.8 2 0 0 2 2 2 0 Up-regulated During Septation BPL_LplA_LipB PF03099.19 CCH62370.1 - 6.1e-14 52.1 0.1 1.1e-13 51.3 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Vps4_C PF09336.10 CCH62370.1 - 0.01 15.8 1.0 0.53 10.3 0.1 3.4 4 0 0 4 4 4 0 Vps4 C terminal oligomerisation domain DUF4168 PF13767.6 CCH62370.1 - 0.055 14.7 0.1 0.14 13.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) HTH_6 PF01418.17 CCH62370.1 - 0.1 12.6 1.4 0.35 10.9 0.3 2.6 2 2 1 3 3 3 0 Helix-turn-helix domain, rpiR family SET PF00856.28 CCH62371.1 - 0.016 15.6 0.0 0.04 14.3 0.0 1.8 1 1 0 1 1 1 0 SET domain YlaH PF14036.6 CCH62373.1 - 0.04 14.3 5.1 0.04 14.3 5.1 3.2 2 2 1 3 3 3 0 YlaH-like protein Yip1 PF04893.17 CCH62373.1 - 2.2 7.9 17.2 1 9.1 4.1 2.1 2 0 0 2 2 2 0 Yip1 domain PI3Ka PF00613.20 CCH62374.1 - 8.3e-68 227.4 0.0 1.1e-66 223.8 0.0 2.3 1 1 1 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CCH62374.1 - 1.4e-50 172.4 1.8 1.2e-33 117.0 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CCH62374.1 - 2.8e-21 75.9 2.5 7.3e-21 74.6 2.5 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Dicer_dimer PF03368.14 CCH62374.1 - 0.14 12.4 0.0 1.7 8.9 0.0 2.7 3 0 0 3 3 3 0 Dicer dimerisation domain Arv1 PF04161.13 CCH62375.1 - 1.3e-59 201.9 6.9 1.3e-59 201.9 6.9 1.4 2 0 0 2 2 2 1 Arv1-like family TIP49 PF06068.13 CCH62377.1 - 1.3e-168 560.7 0.5 1.6e-168 560.4 0.5 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCH62377.1 - 3.1e-21 75.3 0.3 9.1e-21 73.8 0.3 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CCH62377.1 - 1.9e-08 34.8 0.2 8.5e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCH62377.1 - 1.2e-07 31.6 0.1 5.9e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCH62377.1 - 0.0011 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CCH62377.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 CCH62377.1 - 0.015 15.6 2.2 4.5 7.6 0.2 2.5 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCH62377.1 - 0.026 13.9 0.1 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCH62377.1 - 0.028 14.4 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCH62377.1 - 0.034 14.5 0.1 0.16 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CCH62377.1 - 0.051 12.6 0.2 0.31 10.1 0.0 2.3 3 0 0 3 3 3 0 Type II/IV secretion system protein CPT PF07931.12 CCH62377.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 CCH62377.1 - 0.07 12.4 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Cpn60_TCP1 PF00118.24 CCH62378.1 - 2.5e-157 524.5 1.6 2.8e-157 524.3 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.24 CCH62379.1 - 1.7e-52 178.2 0.1 2.2e-52 177.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CCH62379.1 - 1.6e-16 60.3 8.7 1.6e-16 60.3 8.7 2.0 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding CBM39 PF15886.5 CCH62379.1 - 0.082 12.8 0.1 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 32) DUF851 PF05867.11 CCH62379.1 - 0.12 11.8 0.2 0.2 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF851) DHHC PF01529.20 CCH62381.1 - 2.4e-33 115.1 12.0 2.4e-33 115.1 12.0 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase LysE PF01810.18 CCH62381.1 - 6.4 6.2 9.9 0.39 10.1 0.7 2.4 2 1 1 3 3 3 0 LysE type translocator PRELI PF04707.14 CCH62382.1 - 2.9e-53 179.9 1.2 3.8e-53 179.5 1.2 1.1 1 0 0 1 1 1 1 PRELI-like family VirDNA-topo-I_N PF09266.10 CCH62382.1 - 0.021 15.0 0.2 0.059 13.5 0.2 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal DUF3707 PF12499.8 CCH62383.1 - 1.5 9.4 10.6 5.8 7.5 7.9 2.6 2 1 0 2 2 2 0 Pherophorin Thioredoxin PF00085.20 CCH62384.1 - 9e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF5123 PF17161.4 CCH62384.1 - 0.48 11.5 4.9 0.17 12.9 1.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5123) Sec10 PF07393.11 CCH62385.1 - 6.4e-186 619.9 26.9 6.4e-186 619.9 26.9 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec10 GST_C_3 PF14497.6 CCH62385.1 - 0.00034 20.7 0.1 0.0018 18.4 0.1 2.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Occludin_ELL PF07303.13 CCH62385.1 - 0.063 14.0 0.6 0.76 10.5 0.1 3.2 2 1 1 3 3 3 0 Occludin homology domain SAS4 PF15460.6 CCH62386.1 - 3.3e-25 88.0 4.1 3.3e-25 88.0 4.1 2.3 2 1 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PCI PF01399.27 CCH62387.1 - 8.7e-05 23.0 0.7 0.00013 22.4 0.7 1.5 1 0 0 1 1 1 1 PCI domain DUF1827 PF08860.10 CCH62387.1 - 0.026 14.8 1.7 0.79 10.0 1.7 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1827) Sigma70_r1_1 PF03979.14 CCH62387.1 - 0.29 11.2 3.3 1.3 9.2 3.3 2.0 1 1 0 1 1 1 0 Sigma-70 factor, region 1.1 CybS PF05328.12 CCH62388.1 - 9.8e-41 138.6 0.0 1.4e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Peptidase_M16 PF00675.20 CCH62389.1 - 2.6e-51 173.5 0.0 6.8e-51 172.2 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCH62389.1 - 7.5e-38 130.4 0.0 5.5e-36 124.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain HMG_box PF00505.19 CCH62390.1 - 3.3e-11 43.4 2.1 5.9e-11 42.6 2.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCH62390.1 - 1.4e-06 28.8 0.5 3.1e-06 27.7 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain TssC PF17541.2 CCH62390.1 - 0.012 14.5 0.2 0.018 13.9 0.2 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB IPK PF03770.16 CCH62391.1 - 1.6e-46 158.7 0.6 2.1e-46 158.3 0.6 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase PABP PF00658.18 CCH62391.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain CENP-B_dimeris PF09026.10 CCH62391.1 - 0.15 12.4 8.9 0.46 10.9 8.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GP67 PF17634.2 CCH62391.1 - 0.24 11.9 10.9 0.43 11.0 10.9 1.4 1 0 0 1 1 1 0 Gene product 67 DUF2457 PF10446.9 CCH62391.1 - 9.9 5.2 11.6 15 4.5 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sec7 PF01369.20 CCH62392.1 - 5.7e-71 238.0 0.2 2.6e-70 235.9 0.2 2.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CCH62392.1 - 1.9e-38 131.9 0.5 1.9e-38 131.9 0.5 4.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CCH62392.1 - 1.2e-24 86.0 16.4 2.3e-24 85.0 2.4 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 CCH62392.1 - 5.7e-12 45.6 3.1 5.7e-12 45.6 3.1 3.8 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 TEX19 PF15553.6 CCH62392.1 - 0.043 13.8 0.0 0.41 10.6 0.0 2.8 1 1 0 1 1 1 0 Testis-expressed protein 19 AMP-binding PF00501.28 CCH62393.1 - 1.1e-83 281.2 0.0 1.3e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCH62393.1 - 2.6e-23 82.8 0.0 7e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCH62393.1 - 3.8e-18 65.1 2.5 8.2e-18 64.1 2.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Mem_trans PF03547.18 CCH62394.1 - 1.1e-31 109.7 3.9 1.3e-30 106.1 3.9 2.0 1 1 0 1 1 1 1 Membrane transport protein TcpE PF12648.7 CCH62394.1 - 0.12 12.9 0.2 0.12 12.9 0.2 3.6 3 1 0 3 3 3 0 TcpE family Stb3 PF10330.9 CCH62395.1 - 3.8e-29 100.6 0.1 9e-29 99.4 0.1 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein CDC37_N PF03234.14 CCH62396.1 - 2.4e-43 148.1 6.9 2.4e-43 148.1 6.9 4.3 5 1 0 5 5 5 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CCH62396.1 - 1.1e-41 141.5 4.7 1.1e-41 141.5 4.7 2.7 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CCH62396.1 - 2.6e-29 101.3 4.9 2.6e-29 101.3 4.9 3.0 3 1 0 3 3 3 1 Cdc37 C terminal domain hnRNP_Q_AcD PF18360.1 CCH62396.1 - 0.061 13.3 0.2 0.51 10.3 0.2 2.7 1 1 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain KfrA_N PF11740.8 CCH62396.1 - 0.11 13.2 1.3 0.53 11.0 0.0 2.6 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term TFIID_30kDa PF03540.13 CCH62397.1 - 1.8e-24 85.5 0.1 2.8e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Sec5 PF15469.6 CCH62398.1 - 1.3e-47 162.1 16.3 1.3e-47 162.1 16.3 2.5 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.11 CCH62398.1 - 0.046 13.8 6.2 0.048 13.7 1.8 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4477 PF14780.6 CCH62399.1 - 0.13 11.9 8.0 0.26 10.9 0.6 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Glyco_hydro81C PF17652.1 CCH62400.1 - 1.2e-153 511.5 2.4 1.6e-153 511.1 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CCH62400.1 - 1.5e-98 329.9 1.7 1.5e-98 329.9 1.7 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Sec1 PF00995.23 CCH62401.1 - 6.8e-96 322.8 6.4 6.8e-96 322.8 6.4 1.4 2 0 0 2 2 2 1 Sec1 family Pro_dh PF01619.18 CCH62402.1 - 3.8e-55 187.5 0.1 4.7e-55 187.2 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase HNH PF01844.23 CCH62402.1 - 0.1 12.8 2.4 0.32 11.2 2.4 1.8 1 0 0 1 1 1 0 HNH endonuclease Cwf_Cwc_15 PF04889.12 CCH62403.1 - 3e-07 30.4 4.8 3e-07 30.4 4.8 1.8 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.28 CCH62404.1 - 2e-13 49.7 1.2 6.8e-13 48.0 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCH62404.1 - 1.5e-09 37.6 1.0 4.1e-09 36.2 0.0 2.3 4 0 0 4 4 4 1 Variant SH3 domain SH3_2 PF07653.17 CCH62404.1 - 9.7e-06 25.2 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5599 PF18141.1 CCH62404.1 - 0.098 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) TPR_2 PF07719.17 CCH62405.1 - 2.6e-05 24.0 0.2 0.01 15.9 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62405.1 - 9.6e-05 22.3 3.4 0.0058 16.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCH62405.1 - 0.0004 20.1 2.2 0.024 14.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCH62405.1 - 0.0048 17.4 0.7 4.1 8.0 0.0 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCH62405.1 - 0.057 13.7 0.1 0.55 10.6 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCH62405.1 - 0.11 13.4 0.0 7.7 7.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Gly_radical PF01228.21 CCH62405.1 - 0.43 11.1 2.6 0.78 10.3 0.2 2.5 3 0 0 3 3 3 0 Glycine radical TACC_C PF05010.14 CCH62405.1 - 0.81 9.4 17.9 0.019 14.8 3.5 2.8 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TPR_11 PF13414.6 CCH62405.1 - 2.1 8.1 4.8 5.7 6.7 0.0 3.5 4 0 0 4 4 4 0 TPR repeat Na_H_Exchanger PF00999.21 CCH62406.1 - 9.2e-85 284.7 26.4 1.1e-84 284.4 26.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 CCH62406.1 - 2.6e-60 205.0 65.5 4.8e-59 200.8 65.5 2.6 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus YrhC PF14143.6 CCH62406.1 - 0.1 12.7 0.3 0.4 10.8 0.3 2.0 1 0 0 1 1 1 0 YrhC-like protein Methyltransf_16 PF10294.9 CCH62407.1 - 1.5e-08 34.6 2.7 3.3e-06 26.9 0.2 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Semialdhyde_dhC PF02774.18 CCH62408.1 - 1.5e-43 149.0 0.0 2e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CCH62408.1 - 3.6e-32 111.4 0.0 6.7e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CCH62408.1 - 0.047 13.8 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 CCH62408.1 - 0.055 14.2 0.0 0.15 12.8 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ENTH PF01417.20 CCH62409.1 - 1.1e-24 86.8 0.4 1.9e-24 86.1 0.4 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CCH62409.1 - 0.025 13.6 0.0 2.3 7.1 0.0 2.4 2 0 0 2 2 2 0 ANTH domain zf-CCCH PF00642.24 CCH62410.1 - 9.4e-19 66.9 15.0 1.5e-09 37.5 2.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCH62410.1 - 2.3e-10 40.1 18.0 2.7e-05 24.0 4.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CCH62410.1 - 7.2e-07 28.9 12.1 8.3e-05 22.3 1.4 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCH62410.1 - 0.0015 18.9 12.6 0.15 12.6 4.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger N1221 PF07923.13 CCH62410.1 - 0.022 13.9 0.8 0.04 13.1 0.8 1.3 1 0 0 1 1 1 0 N1221-like protein Torus PF16131.5 CCH62410.1 - 0.027 15.2 1.4 0.027 15.2 1.4 3.2 2 1 1 3 3 3 0 Torus domain AWS PF17907.1 CCH62410.1 - 1.5 8.9 3.7 24 5.1 0.1 2.4 2 0 0 2 2 2 0 AWS domain Androgen_recep PF02166.16 CCH62410.1 - 9.4 4.9 10.9 18 4.0 10.9 1.3 1 0 0 1 1 1 0 Androgen receptor Mcp5_PH PF12814.7 CCH62411.1 - 9.1e-42 142.0 0.2 3.1e-41 140.3 0.2 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology SAP PF02037.27 CCH62411.1 - 2.5e-08 33.4 0.0 5.8 6.8 0.1 13.0 15 0 0 15 15 15 1 SAP domain Tup_N PF08581.10 CCH62411.1 - 0.01 16.1 7.8 0.01 16.1 7.8 5.3 5 1 1 6 6 6 0 Tup N-terminal PSD5 PF07637.11 CCH62411.1 - 0.039 14.3 0.0 34 4.9 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1595) Homeodomain PF00046.29 CCH62411.1 - 0.053 13.4 3.8 16 5.5 0.0 5.9 4 0 0 4 4 4 0 Homeodomain PHY PF00360.20 CCH62411.1 - 0.13 11.5 4.2 1.8e+02 1.3 0.0 6.0 4 2 3 7 7 7 0 Phytochrome region Mto2_bdg PF12808.7 CCH62411.1 - 0.43 10.9 6.1 16 5.9 0.0 3.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region T3SS_needle_E PF08988.10 CCH62411.1 - 1.5 9.0 7.9 6.4 7.0 0.1 5.7 5 2 2 7 7 7 0 Type III secretion system, cytoplasmic E component of needle 2-oxoacid_dh PF00198.23 CCH62412.1 - 4.6e-76 255.3 0.1 7.1e-76 254.7 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCH62412.1 - 3e-15 55.8 1.2 5e-15 55.1 1.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.19 CCH62412.1 - 0.00038 20.4 0.4 0.00087 19.2 0.4 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 CCH62412.1 - 0.0004 21.0 0.7 0.0039 17.9 0.6 2.3 1 1 1 2 2 2 1 HlyD family secretion protein CABS1 PF15367.6 CCH62412.1 - 0.0036 16.5 1.4 0.0036 16.5 1.4 1.6 2 0 0 2 2 2 1 Calcium-binding and spermatid-specific protein 1 Biotin_lipoyl_2 PF13533.6 CCH62412.1 - 0.004 16.9 0.0 0.058 13.2 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like FAP PF07174.11 CCH62412.1 - 0.55 9.6 17.0 0.89 8.9 17.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) zf-C2H2 PF00096.26 CCH62413.1 - 1.3e-09 38.0 15.1 0.0031 17.9 3.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH62413.1 - 2.2e-05 24.9 13.8 0.049 14.5 1.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCH62413.1 - 0.046 14.2 0.2 0.046 14.2 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CCH62413.1 - 0.18 11.9 5.1 0.4 10.8 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH62413.1 - 5.3 7.4 5.5 40 4.6 0.3 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zip PF02535.22 CCH62414.1 - 2.9e-80 270.0 5.5 3.6e-80 269.7 5.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Connexin PF00029.19 CCH62414.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Connexin UNC-50 PF05216.13 CCH62414.1 - 0.85 9.1 9.1 0.15 11.6 2.8 2.2 2 1 0 2 2 2 0 UNC-50 family DUF4728 PF15860.5 CCH62414.1 - 9.7 7.0 7.3 7.1 7.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4728) TFIID_20kDa PF03847.13 CCH62415.1 - 1.8e-25 89.2 2.6 6.2e-25 87.5 2.6 2.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CCH62415.1 - 0.0064 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCH62415.1 - 0.0069 16.4 1.1 0.028 14.5 0.0 2.6 2 1 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit zf-C4H2 PF10146.9 CCH62415.1 - 0.62 10.3 19.8 0.025 14.9 7.5 2.3 1 1 0 2 2 2 0 Zinc finger-containing protein AviRa PF11599.8 CCH62415.1 - 1.7 8.0 8.5 0.34 10.3 3.9 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Asp PF00026.23 CCH62416.1 - 4.5e-68 230.0 16.0 9.4e-58 196.1 6.9 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH62416.1 - 6.8e-09 36.2 10.3 9.4e-09 35.7 3.7 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal MFMR_assoc PF16596.5 CCH62416.1 - 4.2 7.8 19.5 2.7 8.5 8.2 2.5 2 0 0 2 2 2 0 Disordered region downstream of MFMR Mod_r PF07200.13 CCH62417.1 - 1.1e-16 61.3 19.4 1.1e-16 61.3 19.4 1.7 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Nup54 PF13874.6 CCH62417.1 - 0.051 13.7 6.9 0.066 13.3 6.0 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Enkurin PF13864.6 CCH62417.1 - 1.8 9.0 13.9 1.7 9.1 10.8 2.5 2 1 0 2 2 2 0 Calmodulin-binding YojJ PF10372.9 CCH62417.1 - 5.9 7.1 10.4 4.4 7.5 1.9 2.9 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus ubiquitin PF00240.23 CCH62418.1 - 1.7e-15 56.5 0.7 2e-15 56.3 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCH62418.1 - 3.9e-09 36.2 0.4 4.5e-09 36.0 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCH62418.1 - 0.082 13.4 0.1 0.091 13.2 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Rgp1 PF08737.10 CCH62419.1 - 8.9e-91 305.1 11.2 8.9e-91 305.1 11.2 2.0 2 0 0 2 2 2 1 Rgp1 Pkinase PF00069.25 CCH62420.1 - 7.6e-68 228.7 1.8 2.4e-67 227.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62420.1 - 5.1e-32 111.2 0.4 1.7e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCH62420.1 - 3.3e-06 26.3 0.1 3.3e-06 26.3 0.1 2.2 2 0 0 2 2 1 1 Haspin like kinase domain APH PF01636.23 CCH62420.1 - 0.0011 18.9 8.1 0.0028 17.6 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 CCH62420.1 - 0.066 12.8 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FAM199X PF15814.5 CCH62420.1 - 0.17 10.9 4.6 0.26 10.3 4.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X Neur_chan_memb PF02932.16 CCH62420.1 - 0.2 11.7 4.8 0.27 11.3 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase_fungal PF17667.1 CCH62420.1 - 0.21 10.3 8.3 0.85 8.3 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase TFIIA PF03153.13 CCH62420.1 - 0.54 10.2 40.8 0.74 9.7 40.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 CCH62420.1 - 2.4 7.8 17.0 4 7.1 17.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) UPF0565 PF10561.9 CCH62420.1 - 5.5 6.1 17.9 9.2 5.4 17.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Exonuc_VII_L PF02601.15 CCH62420.1 - 5.7 6.4 24.1 8 5.9 24.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Plasmodium_Vir PF05795.11 CCH62420.1 - 5.9 6.2 12.3 8.9 5.6 12.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PepSY_2 PF13670.6 CCH62420.1 - 6.7 6.8 10.1 14 5.8 10.1 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Flocculin_t3 PF13928.6 CCH62421.1 - 1.6e-11 44.6 13.0 1.6e-11 44.6 13.0 3.1 3 0 0 3 3 3 1 Flocculin type 3 repeat Redoxin PF08534.10 CCH62422.1 - 8e-32 110.0 0.1 9.4e-32 109.7 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CCH62422.1 - 6.9e-08 32.4 0.0 9.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Hydrolase PF00702.26 CCH62422.1 - 0.028 14.7 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FIN1 PF17300.2 CCH62423.1 - 6.6e-09 35.6 24.6 1.3e-08 34.7 23.8 2.0 1 1 0 1 1 1 1 Filaments in between nuclei protein-1 PPI_Ypi1 PF07491.11 CCH62424.1 - 0.055 13.3 0.4 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 Protein phosphatase inhibitor SUIM_assoc PF16619.5 CCH62424.1 - 0.085 12.9 7.1 0.13 12.4 7.1 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CCH62424.1 - 0.17 11.1 1.4 0.22 10.7 1.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2967 PF11179.8 CCH62424.1 - 0.97 7.5 2.3 1.3 7.1 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) CH PF00307.31 CCH62425.1 - 6.8e-85 280.5 0.5 1.1e-21 77.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CCH62425.1 - 8.5e-07 29.3 0.4 2.5e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair CH_2 PF06294.11 CCH62425.1 - 0.0021 18.1 0.1 28 4.9 0.0 4.3 4 1 0 4 4 4 1 CH-like domain in sperm protein EF-hand_6 PF13405.6 CCH62425.1 - 0.031 14.2 0.1 3.2 7.9 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CCH62425.1 - 0.097 12.3 0.2 16 5.4 0.0 3.3 3 0 0 3 3 3 0 EF hand SUFU_C PF12470.8 CCH62426.1 - 0.066 13.3 2.1 0.086 12.9 2.1 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Myc_N PF01056.18 CCH62426.1 - 0.14 12.1 6.1 0.14 12.0 6.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Zip PF02535.22 CCH62426.1 - 0.48 9.6 2.4 0.51 9.5 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 CCH62426.1 - 1 8.7 7.9 1.3 8.4 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sporozoite_P67 PF05642.11 CCH62426.1 - 1.6 6.7 8.0 2 6.4 8.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 CCH62426.1 - 8 5.7 11.6 9.8 5.4 11.6 1.1 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_1 PF00561.20 CCH62427.1 - 3.9e-16 59.5 5.1 2.5e-15 56.8 5.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH62427.1 - 1e-12 47.9 0.0 1.5e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCH62427.1 - 1.3e-08 35.8 0.0 3.6e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CCH62427.1 - 3.5e-05 23.3 3.7 0.004 16.5 0.5 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 CCH62427.1 - 0.00013 20.8 0.0 0.0026 16.5 0.0 2.1 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 CCH62427.1 - 0.0002 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 CCH62427.1 - 0.0022 17.6 0.0 0.048 13.2 0.0 2.3 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF676 PF05057.14 CCH62427.1 - 0.011 15.2 1.2 0.65 9.5 0.0 2.8 3 0 0 3 3 3 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 CCH62427.1 - 0.015 15.4 0.0 0.33 11.0 0.0 2.6 3 0 0 3 3 3 0 Thioesterase domain Abhydrolase_5 PF12695.7 CCH62427.1 - 0.023 14.4 0.3 0.26 11.1 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CCH62427.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 CCH62427.1 - 0.035 13.6 0.1 4.3 6.8 0.0 2.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family BAAT_C PF08840.11 CCH62427.1 - 0.043 13.7 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 CCH62427.1 - 0.2 11.5 0.0 3.5 7.4 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold F-box-like PF12937.7 CCH62428.1 - 2.7e-05 23.9 0.1 4.6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 F-box-like MIT PF04212.18 CCH62428.1 - 0.00059 19.9 0.9 0.0019 18.3 0.6 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain F-box PF00646.33 CCH62428.1 - 0.0022 17.8 0.4 0.0044 16.9 0.4 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 CCH62428.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62428.1 - 0.075 13.3 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62428.1 - 0.083 13.1 0.0 0.36 11.0 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62428.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 TPR repeat Complex1_LYR PF05347.15 CCH62428.1 - 5.8 7.0 7.2 0.56 10.3 1.2 2.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Nyv1_N PF09426.10 CCH62429.1 - 5e-54 182.1 1.3 5e-54 182.1 1.3 1.6 2 0 0 2 2 2 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.21 CCH62429.1 - 2.8e-25 87.9 5.4 2.8e-25 87.9 5.4 1.9 1 1 1 2 2 2 1 Synaptobrevin L27_1 PF09058.10 CCH62429.1 - 0.00079 19.4 0.4 0.0028 17.6 0.0 2.1 2 0 0 2 2 2 1 L27_1 LMBR1 PF04791.16 CCH62429.1 - 0.002 17.1 0.8 0.002 17.1 0.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Ribonuc_red_2_N PF08471.10 CCH62429.1 - 0.015 15.5 0.3 0.13 12.4 0.3 2.2 1 1 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase ADIP PF11559.8 CCH62429.1 - 0.016 15.3 9.7 0.023 14.8 9.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FtsK_SpoIIIE PF01580.18 CCH62429.1 - 0.016 14.6 0.3 0.021 14.2 0.3 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family EMP24_GP25L PF01105.24 CCH62429.1 - 0.044 13.7 8.4 0.62 10.0 8.4 2.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PrmA PF06325.13 CCH62429.1 - 0.057 12.8 2.4 0.098 12.0 2.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4413 PF14372.6 CCH62429.1 - 2.7 8.4 8.2 1.6 9.2 3.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4413) CBFD_NFYB_HMF PF00808.23 CCH62430.1 - 3.3e-05 24.1 0.0 9.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF792 PF05632.11 CCH62430.1 - 0.25 11.2 2.3 0.21 11.5 0.3 1.7 2 0 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF792) Histone PF00125.24 CCH62430.1 - 0.28 11.5 0.0 0.28 11.5 0.0 2.6 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 TRM PF02005.16 CCH62431.1 - 2.4e-142 474.6 0.0 3.2e-142 474.2 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CCH62431.1 - 5.3e-05 23.1 0.1 0.0001 22.1 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CCH62431.1 - 0.14 12.9 0.0 0.39 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 CCH62431.1 - 0.15 11.7 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EMP70 PF02990.16 CCH62432.1 - 1.8e-191 637.4 17.4 1.8e-191 637.4 17.4 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Actin PF00022.19 CCH62433.1 - 8.4e-52 176.1 0.0 2.4e-50 171.4 0.0 2.5 1 1 0 1 1 1 1 Actin PEX-2N PF09263.10 CCH62433.1 - 0.12 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Opy2 PF09463.10 CCH62434.1 - 2.1e-09 37.5 17.7 3.2e-09 36.9 17.7 1.3 1 0 0 1 1 1 1 Opy2 protein Herpes_gE PF02480.16 CCH62434.1 - 0.0088 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.20 CCH62434.1 - 0.06 13.3 0.3 0.42 10.6 0.0 2.4 3 0 0 3 3 3 0 Syndecan domain YajC PF02699.15 CCH62434.1 - 0.061 13.2 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit Orf78 PF06024.12 CCH62434.1 - 0.95 9.8 0.0 0.95 9.8 0.0 3.2 3 1 0 3 3 3 0 Orf78 (ac78) Transketolase_N PF00456.21 CCH62435.1 - 1.4e-155 517.4 0.0 2e-155 516.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CCH62435.1 - 1.5e-43 148.6 0.0 2.4e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCH62435.1 - 7.4e-11 42.0 0.0 1.6e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CCH62435.1 - 0.0018 17.5 0.0 0.0031 16.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CCH62435.1 - 0.0022 17.0 0.0 0.005 15.8 0.0 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component Not3 PF04065.15 CCH62436.1 - 1.6e-29 103.0 9.9 1.6e-29 103.0 9.9 4.5 3 1 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCH62436.1 - 1.2e-24 86.9 39.8 2.3e-23 82.7 32.4 4.2 2 2 1 3 3 3 1 NOT2 / NOT3 / NOT5 family Presenilin PF01080.17 CCH62436.1 - 0.0044 15.8 19.7 0.0044 15.8 19.7 2.2 2 0 0 2 2 2 1 Presenilin DUF5053 PF16476.5 CCH62436.1 - 0.03 14.0 0.7 0.091 12.4 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) PepSY_TM PF03929.16 CCH62436.1 - 0.27 10.9 0.7 0.44 10.2 0.7 1.4 1 0 0 1 1 1 0 PepSY-associated TM region Macoilin PF09726.9 CCH62436.1 - 0.88 8.0 42.2 1.2 7.7 14.5 2.1 2 0 0 2 2 2 0 Macoilin family MMR1 PF08505.10 CCH62436.1 - 1.6 9.0 56.4 0.032 14.5 22.7 2.7 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein NAD_binding_4 PF07993.12 CCH62437.1 - 3.9e-70 236.0 0.0 7e-70 235.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CCH62437.1 - 2.1e-69 234.2 0.0 2.8e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CCH62437.1 - 2.4e-14 53.4 0.0 5.8e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CCH62437.1 - 2.2e-09 37.1 0.0 3.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCH62437.1 - 0.00035 19.7 0.1 0.0017 17.4 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CCH62437.1 - 0.01 16.8 0.1 0.047 14.7 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 CCH62437.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Condensation PF00668.20 CCH62437.1 - 0.013 14.2 0.1 0.044 12.4 0.1 1.8 2 0 0 2 2 2 0 Condensation domain SNF2_N PF00176.23 CCH62438.1 - 5.7e-55 186.4 0.1 2.1e-54 184.6 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH62438.1 - 1.1e-14 54.7 0.0 2.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CCH62438.1 - 7e-09 35.4 9.6 7e-09 35.4 9.6 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CCH62438.1 - 1.1e-07 32.1 0.0 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCH62438.1 - 6.2e-07 29.4 0.0 1.6e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase YL1 PF05764.13 CCH62438.1 - 5.5e-06 26.7 6.9 8.3e-06 26.1 6.9 1.3 1 0 0 1 1 1 1 YL1 nuclear protein zf-C3HC4_2 PF13923.6 CCH62438.1 - 0.00014 21.6 8.9 0.00014 21.6 8.9 2.6 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCH62438.1 - 0.00058 19.7 6.5 0.00058 19.7 6.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH62438.1 - 0.0014 18.8 10.0 0.0014 18.8 10.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CCH62438.1 - 0.0014 18.6 6.0 0.0014 18.6 6.0 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCH62438.1 - 0.0038 17.5 8.8 0.0038 17.5 8.8 2.5 2 0 0 2 2 2 1 Ring finger domain MH2 PF03166.14 CCH62438.1 - 0.011 16.0 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 MH2 domain DUF3410 PF11890.8 CCH62438.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Drc1-Sld2 PF11719.8 CCH62438.1 - 0.89 9.0 15.4 1.3 8.5 15.4 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Zn_Tnp_IS91 PF14319.6 CCH62438.1 - 1.3 9.1 11.7 0.19 11.8 1.8 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain BUD22 PF09073.10 CCH62438.1 - 3.9 6.7 17.4 6.2 6.1 17.4 1.2 1 0 0 1 1 1 0 BUD22 TPR_1 PF00515.28 CCH62439.1 - 1e-47 158.1 17.7 8.7e-07 28.5 0.0 11.2 12 1 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62439.1 - 4.4e-46 151.3 8.5 0.00011 22.0 0.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62439.1 - 7.3e-35 116.3 8.6 0.0073 16.4 0.0 10.2 11 0 0 11 11 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 CCH62439.1 - 2.1e-29 99.7 23.2 4.3e-05 23.6 0.1 12.2 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62439.1 - 6.7e-27 92.9 16.4 9.9e-06 25.2 0.0 9.7 5 2 5 10 10 9 6 TPR repeat TPR_14 PF13428.6 CCH62439.1 - 1.9e-25 87.4 2.1 0.0023 18.6 0.0 9.6 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 CCH62439.1 - 2.7e-22 79.1 1.0 0.00028 21.3 1.1 5.7 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCH62439.1 - 1.4e-21 76.6 13.5 5.6e-05 23.4 0.1 7.2 4 2 3 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 CCH62439.1 - 6.6e-19 66.5 7.3 0.002 18.0 0.1 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 CCH62439.1 - 9.7e-18 64.6 4.3 0.00085 19.9 0.1 5.8 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCH62439.1 - 6.5e-16 57.8 6.5 2 9.2 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 CCH62439.1 - 1.2e-11 44.6 2.4 0.016 15.4 0.0 5.8 2 2 4 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 CCH62439.1 - 5.7e-10 38.9 2.2 0.0031 16.8 0.0 4.8 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCH62439.1 - 2e-07 30.6 6.4 0.45 10.5 0.2 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH62439.1 - 1.3e-06 28.5 17.9 0.0013 18.9 0.0 4.1 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CCH62439.1 - 2.3e-05 23.9 0.7 0.77 9.1 0.8 3.6 2 1 1 3 3 3 2 MalT-like TPR region TPR_21 PF09976.9 CCH62439.1 - 8.2e-05 22.4 3.8 2.4 7.9 1.7 5.0 5 1 0 5 5 4 1 Tetratricopeptide repeat-like domain ChAPs PF09295.10 CCH62439.1 - 8.8e-05 21.7 2.4 0.64 9.0 0.1 3.7 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 CCH62439.1 - 0.00039 19.5 0.5 1.2 7.9 0.0 3.6 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 RPN7 PF10602.9 CCH62439.1 - 0.0015 18.3 1.6 7.7 6.2 0.0 4.2 2 2 2 4 4 4 0 26S proteasome subunit RPN7 BTAD PF03704.17 CCH62439.1 - 0.0028 18.1 1.2 1.2 9.6 0.0 3.1 3 1 1 4 4 3 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 CCH62439.1 - 0.038 14.3 0.0 8.2 6.8 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 CCH62439.1 - 0.039 13.7 0.0 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2225 PF09986.9 CCH62439.1 - 0.16 11.7 1.7 16 5.1 0.1 3.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 CCH62439.1 - 8.3 6.6 6.9 16 5.6 0.2 4.3 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Med1 PF10744.9 CCH62440.1 - 2.3e-69 234.5 15.4 2.3e-69 234.5 15.4 1.6 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 DUF3440 PF11922.8 CCH62440.1 - 0.14 11.9 1.4 0.27 10.9 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3440) Spore_III_AF PF09581.10 CCH62440.1 - 2.1 8.3 9.1 0.32 11.0 0.7 3.1 3 0 0 3 3 3 0 Stage III sporulation protein AF (Spore_III_AF) Spermine_synth PF01564.17 CCH62441.1 - 3.8e-75 251.5 0.0 5.3e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCH62441.1 - 1.9e-26 91.7 0.1 3.5e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CCH62441.1 - 0.0038 17.9 0.0 0.0075 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF226 PF02890.14 CCH62441.1 - 0.039 14.0 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Methyltransf_12 PF08242.12 CCH62441.1 - 0.1 13.3 0.1 0.38 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Glycos_transf_1 PF00534.20 CCH62442.1 - 2.6e-12 46.6 0.0 4.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCH62442.1 - 3.6e-08 33.9 0.0 3.3e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCH62442.1 - 4.3e-07 30.1 0.0 6.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CCH62442.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 CCH62442.1 - 0.021 14.8 0.2 0.054 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase 4-like EF-hand_1 PF00036.32 CCH62443.1 - 6.7e-30 100.4 7.5 5.6e-09 34.9 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCH62443.1 - 4.4e-29 100.7 2.6 1.9e-15 57.1 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCH62443.1 - 4.6e-26 88.5 4.4 6.5e-09 35.0 0.0 4.7 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CCH62443.1 - 1.7e-21 75.8 7.8 3.4e-11 42.8 0.1 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CCH62443.1 - 2.1e-16 58.6 8.7 2.1e-08 33.3 0.0 4.6 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 CCH62443.1 - 4.8e-14 52.4 0.0 3.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCH62443.1 - 9.7e-08 32.3 0.2 0.0034 17.7 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CCH62443.1 - 1.8e-06 27.9 0.9 1.9e-05 24.6 0.1 2.1 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 CCH62443.1 - 3.4e-05 23.8 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 CCH62443.1 - 7.4e-05 23.0 0.2 0.028 14.8 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 CCH62443.1 - 0.0023 18.8 0.0 0.53 11.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain DUF892 PF05974.12 CCH62443.1 - 0.012 15.7 0.2 2 8.4 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF892) EFhand_Ca_insen PF08726.10 CCH62443.1 - 0.016 15.3 0.3 0.033 14.3 0.0 1.7 2 0 0 2 2 1 0 Ca2+ insensitive EF hand Caleosin PF05042.13 CCH62443.1 - 0.02 14.8 0.0 6.5 6.7 0.0 2.9 1 1 2 3 3 3 0 Caleosin related protein Glycos_trans_3N PF02885.17 CCH62443.1 - 0.024 14.5 1.4 0.13 12.1 0.0 2.8 3 1 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Dockerin_1 PF00404.18 CCH62443.1 - 0.031 14.5 0.1 0.21 11.8 0.1 2.3 1 1 0 1 1 1 0 Dockerin type I domain AIM3 PF17096.5 CCH62444.1 - 3.3e-24 85.6 29.0 3.3e-24 85.6 29.0 14.6 11 6 0 11 11 11 1 Altered inheritance of mitochondria protein 3 Fe-S_biosyn PF01521.20 CCH62445.1 - 2.6e-11 43.7 0.1 2.3e-07 31.0 0.1 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ThiF PF00899.21 CCH62446.1 - 1.1e-44 152.6 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Malic_M PF03949.15 CCH62446.1 - 0.016 14.5 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Peptidase_S48 PF03574.15 CCH62446.1 - 0.11 12.7 0.1 0.39 10.9 0.1 1.8 1 1 1 2 2 2 0 Peptidase family S48 Pho88 PF10032.9 CCH62447.1 - 2.5e-75 251.7 0.3 2.8e-75 251.6 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ArsP_1 PF03773.13 CCH62447.1 - 0.072 12.2 0.2 0.092 11.9 0.2 1.1 1 0 0 1 1 1 0 Predicted permease Septin PF00735.18 CCH62448.1 - 4.4e-107 357.5 3.1 4.4e-107 357.5 3.1 2.5 1 1 1 2 2 2 1 Septin MMR_HSR1 PF01926.23 CCH62448.1 - 7.5e-08 32.5 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CCH62448.1 - 0.00029 20.3 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 CCH62448.1 - 0.0003 20.9 4.8 0.21 11.7 0.0 3.4 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 CCH62448.1 - 0.00032 20.7 0.3 0.00032 20.7 0.3 3.4 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CCH62448.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 CCH62448.1 - 0.0023 18.2 0.0 0.006 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Roc PF08477.13 CCH62448.1 - 0.0026 18.0 0.1 0.0073 16.5 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CCH62448.1 - 0.0028 17.2 2.8 0.12 11.9 0.1 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 CCH62448.1 - 0.0044 16.1 0.1 0.0099 15.0 0.1 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 CCH62448.1 - 0.0089 16.4 0.0 0.023 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 CCH62448.1 - 0.0091 16.4 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Helo_like_N PF17111.5 CCH62448.1 - 0.021 14.2 0.7 0.04 13.3 0.7 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins AAA_29 PF13555.6 CCH62448.1 - 0.027 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 CCH62448.1 - 0.039 13.6 0.0 0.15 11.6 0.0 2.0 1 1 1 2 2 2 0 Ras family AAA_33 PF13671.6 CCH62448.1 - 0.049 13.8 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 CCH62448.1 - 0.058 13.2 0.1 8.5 6.1 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 CCH62448.1 - 0.078 12.7 1.9 0.11 12.2 0.2 2.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CCH62448.1 - 0.56 10.7 5.0 0.17 12.4 0.6 2.3 2 1 0 2 2 2 0 ABC transporter SIS PF01380.22 CCH62449.1 - 6.3e-64 213.7 0.0 1.3e-31 109.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CCH62449.1 - 3.5e-14 53.1 0.0 7e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCH62449.1 - 4.2e-08 33.1 0.0 8.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CCH62449.1 - 6.1e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pyr_redox_2 PF07992.14 CCH62450.1 - 7e-50 169.9 0.0 8.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCH62450.1 - 7e-19 68.2 0.1 2.7e-16 59.9 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCH62450.1 - 2.6e-15 56.5 0.0 8.7e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCH62450.1 - 3.8e-06 26.2 0.7 0.57 9.2 0.1 4.2 4 1 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CCH62450.1 - 0.00041 20.8 0.0 0.16 12.5 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CCH62450.1 - 0.00055 20.1 0.1 0.035 14.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCH62450.1 - 0.0035 16.5 1.2 0.78 8.7 0.2 2.6 3 1 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 CCH62450.1 - 0.0066 15.7 0.1 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CCH62450.1 - 0.023 13.8 0.0 2 7.5 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CCH62450.1 - 0.032 13.5 0.0 3 7.0 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 CCH62450.1 - 0.055 13.5 0.0 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CCDC158 PF15921.5 CCH62450.1 - 0.22 9.3 0.1 0.3 8.9 0.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 PQ-loop PF04193.14 CCH62451.1 - 1.4e-31 108.0 5.3 9.7e-16 57.3 0.5 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 CCH62451.1 - 0.0049 16.9 2.6 0.73 9.9 4.4 2.7 2 1 0 2 2 2 1 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.18 CCH62451.1 - 0.016 16.0 0.1 0.016 16.0 0.1 1.9 3 0 0 3 3 3 0 ER lumen protein retaining receptor SBE2 PF17076.5 CCH62452.1 - 6e-158 527.6 57.3 2.2e-156 522.4 57.3 2.0 1 1 0 1 1 1 1 SBE2, cell-wall formation Pkinase PF00069.25 CCH62453.1 - 7.7e-67 225.4 0.2 1.7e-66 224.3 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62453.1 - 1.8e-47 161.8 0.0 4.9e-47 160.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCH62453.1 - 4.3e-05 22.5 0.0 4.3e-05 22.5 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CCH62453.1 - 0.00017 21.0 0.0 0.0006 19.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like DUF3388 PF11868.8 CCH62454.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) Glyco_hydro_114 PF03537.13 CCH62454.1 - 0.095 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 Ac76 PF05814.11 CCH62454.1 - 0.19 11.8 6.7 0.23 11.5 2.5 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) OAD_gamma PF04277.13 CCH62454.1 - 0.68 10.6 5.9 5.8 7.6 4.4 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Asp PF00026.23 CCH62455.1 - 4.4e-25 88.8 0.0 9.6e-24 84.4 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCH62455.1 - 0.0084 16.4 0.0 0.023 14.9 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Sec23_trunk PF04811.15 CCH62456.1 - 3.7e-57 193.7 0.0 7.5e-57 192.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCH62456.1 - 1.2e-19 70.0 0.4 3.6e-19 68.5 0.3 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCH62456.1 - 2.9e-11 43.2 3.4 8e-11 41.8 3.4 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CCH62456.1 - 9.6e-08 32.7 0.0 2.9e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CCH62456.1 - 1e-06 28.5 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 CCH62456.1 - 0.075 13.7 0.0 1.2 9.8 0.0 2.6 2 0 0 2 2 2 0 von Willebrand factor type A domain Pal1 PF08316.11 CCH62457.1 - 2.8e-49 167.4 0.8 2.8e-49 167.4 0.8 4.6 2 2 2 4 4 4 1 Pal1 cell morphology protein Sod_Fe_C PF02777.18 CCH62458.1 - 1.1e-15 57.7 1.0 3.8e-07 30.2 0.0 2.5 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Svf1 PF08622.10 CCH62459.1 - 2.2e-67 226.2 1.0 3.7e-67 225.4 1.0 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CCH62459.1 - 4.2e-66 221.8 1.5 9e-66 220.8 1.5 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain DUF3612 PF12268.8 CCH62459.1 - 0.14 12.3 0.0 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3612) Nop14 PF04147.12 CCH62459.1 - 1 7.5 9.4 1.4 7.1 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 CCH62459.1 - 1.1 9.0 9.6 3.3 7.4 9.6 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein tRNA-synt_1d PF00750.19 CCH62460.1 - 3.5e-120 401.1 6.0 4.3e-120 400.8 6.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CCH62460.1 - 1.3e-28 99.6 0.0 3.3e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CCH62460.1 - 3.9e-10 40.2 0.0 1.3e-09 38.5 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Cpn60_TCP1 PF00118.24 CCH62461.1 - 7.8e-154 512.9 14.5 8.8e-154 512.7 14.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bac_DnaA PF00308.18 CCH62461.1 - 0.0029 17.5 0.1 0.27 11.0 0.1 2.7 1 1 1 2 2 2 2 Bacterial dnaA protein HTH_19 PF12844.7 CCH62461.1 - 0.044 13.8 0.2 4.3 7.4 0.1 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Fcf1 PF04900.12 CCH62462.1 - 6.2e-33 113.1 0.7 9.7e-33 112.5 0.1 1.6 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CCH62462.1 - 6.2e-14 52.3 0.0 9.9e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 CCH62462.1 - 0.0086 16.4 0.0 0.021 15.1 0.0 1.6 2 0 0 2 2 2 1 NTF2 fold immunity protein ING PF12998.7 CCH62463.1 - 2.4e-13 50.5 5.4 2.4e-13 50.5 5.4 2.4 3 1 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCH62463.1 - 4e-06 26.6 7.7 4e-06 26.6 7.7 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 CCH62463.1 - 0.039 14.2 4.5 0.048 13.9 1.5 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain PDCD7 PF16021.5 CCH62463.1 - 0.11 11.6 8.3 0.017 14.3 2.0 2.1 1 1 1 2 2 2 0 Programmed cell death protein 7 Utp14 PF04615.13 CCH62463.1 - 0.79 8.2 17.9 0.98 7.9 17.9 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 CCH62463.1 - 0.88 8.0 15.9 1.3 7.5 15.9 1.3 1 0 0 1 1 1 0 Macoilin family MatE PF01554.18 CCH62464.1 - 1.8e-62 209.8 36.7 6.4e-40 136.5 9.1 3.1 3 0 0 3 3 3 2 MatE DUF818 PF05677.12 CCH62464.1 - 0.093 11.7 1.2 0.14 11.0 1.2 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Brix PF04427.18 CCH62465.1 - 9.6e-26 91.1 1.3 1.8e-25 90.2 1.3 1.4 1 0 0 1 1 1 1 Brix domain Pex19 PF04614.12 CCH62465.1 - 0.013 15.3 1.6 0.018 14.8 1.6 1.3 1 0 0 1 1 1 0 Pex19 protein family RRM_1 PF00076.22 CCH62466.1 - 5e-40 135.2 0.1 2.2e-15 56.2 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH62466.1 - 0.00041 20.4 2.2 0.74 10.0 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 CCH62466.1 - 0.003 17.6 0.1 0.003 17.6 0.1 3.0 3 1 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.6 CCH62466.1 - 0.056 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif STE PF02200.16 CCH62467.1 - 7.3e-57 190.5 2.7 1.7e-56 189.3 2.7 1.7 1 0 0 1 1 1 1 STE like transcription factor ResIII PF04851.15 CCH62468.1 - 2.9e-29 102.3 0.0 2.9e-29 102.3 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCH62468.1 - 3.6e-14 52.9 1.5 7.7e-14 51.8 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH62468.1 - 4.1e-14 52.8 10.6 6.8e-14 52.2 0.4 4.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF2075 PF09848.9 CCH62468.1 - 0.00014 21.3 1.2 0.00075 18.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CCH62468.1 - 0.0039 17.5 1.2 0.043 14.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain NPC1_N PF16414.5 CCH62468.1 - 0.21 11.1 1.5 0.43 10.1 0.1 2.0 2 0 0 2 2 2 0 Niemann-Pick C1 N terminus AAA_11 PF13086.6 CCH62468.1 - 1.3 8.8 7.2 3 7.5 0.1 3.2 2 2 1 3 3 3 0 AAA domain Pkinase PF00069.25 CCH62469.1 - 3.5e-43 147.9 5.9 3.2e-40 138.2 1.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62469.1 - 4.8e-23 81.8 0.2 2.1e-22 79.7 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH62469.1 - 0.00043 19.7 0.0 0.00078 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Peptidase_C13 PF01650.18 CCH62470.1 - 1e-44 153.0 0.3 1e-44 153.0 0.3 1.8 2 0 0 2 2 2 1 Peptidase C13 family Put_DNA-bind_N PF06971.13 CCH62470.1 - 0.12 12.4 0.1 3 7.9 0.0 2.8 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Thioredoxin_7 PF13899.6 CCH62471.1 - 2.2e-21 75.8 0.0 4.5e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 CCH62471.1 - 1e-12 47.6 0.2 4.7e-12 45.5 0.3 2.1 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 CCH62471.1 - 1.6e-12 47.4 0.1 4.2e-12 46.1 0.1 1.8 1 0 0 1 1 1 1 UBX domain C2-set PF05790.15 CCH62471.1 - 0.0076 16.4 0.2 0.02 15.1 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin C2-set domain Thioredoxin_2 PF13098.6 CCH62471.1 - 0.095 13.2 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Peroxin-3 PF04882.12 CCH62472.1 - 1.3e-51 176.1 29.3 1.5e-42 146.2 24.2 3.1 1 1 1 2 2 2 2 Peroxin-3 Secretin_N_2 PF07655.13 CCH62472.1 - 0.0001 22.8 9.9 0.00011 22.7 5.8 2.4 2 0 0 2 2 2 1 Secretin N-terminal domain Connexin PF00029.19 CCH62472.1 - 0.88 9.3 8.5 0.57 9.9 1.9 2.5 2 1 1 3 3 3 0 Connexin Skp1 PF01466.19 CCH62473.1 - 8.7e-25 86.6 0.1 1.4e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CCH62473.1 - 2e-12 47.1 0.1 6.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain VASt PF16016.5 CCH62474.1 - 4.3e-71 238.3 7.7 9.8e-36 123.5 0.1 4.3 4 0 0 4 4 4 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCH62474.1 - 1.4e-26 92.6 0.1 6.6e-26 90.4 0.1 2.3 1 0 0 1 1 1 1 GRAM domain Cnd3 PF12719.7 CCH62475.1 - 2.9e-90 302.5 9.5 4.6e-89 298.5 7.0 2.6 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CCH62475.1 - 1.6e-08 34.1 2.1 0.6 10.5 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Adaptin_N PF01602.20 CCH62475.1 - 4.6e-07 28.8 4.0 0.0011 17.6 0.0 3.5 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 CCH62475.1 - 7e-05 22.9 0.1 7e-05 22.9 0.1 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCH62475.1 - 0.0015 18.9 0.1 0.074 13.5 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats Cohesin_HEAT PF12765.7 CCH62475.1 - 0.0021 18.3 0.1 6.1 7.3 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.8 CCH62475.1 - 0.013 15.1 0.8 0.35 10.4 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal UNC45-central PF11701.8 CCH62475.1 - 0.019 15.0 6.2 0.051 13.5 0.2 4.1 3 2 0 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 CCH62475.1 - 0.14 12.7 0.8 1.7 9.3 0.1 3.3 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CCH62475.1 - 0.22 12.1 0.2 16 6.1 0.1 3.6 3 1 1 4 4 4 0 HEAT-like repeat FANCI_S2 PF14676.6 CCH62475.1 - 0.25 11.6 3.4 3.2 8.0 0.0 3.5 4 0 0 4 4 4 0 FANCI solenoid 2 ABA_GPCR PF12430.8 CCH62476.1 - 2.8e-59 199.9 4.8 2.8e-59 199.9 4.8 2.4 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CCH62476.1 - 1.3e-16 60.4 1.1 3.6e-16 59.0 1.1 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal FYVE PF01363.21 CCH62477.1 - 3.6e-18 65.5 29.6 1.6e-14 53.8 6.7 3.5 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 CCH62477.1 - 5.9e-16 57.9 2.9 1.5e-15 56.6 2.9 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.6 CCH62477.1 - 0.017 16.0 0.1 0.017 16.0 0.1 5.4 6 1 1 7 7 7 0 C2H2-type zinc finger zf-met2 PF12907.7 CCH62477.1 - 0.027 14.6 2.8 2.6 8.3 0.6 2.7 2 0 0 2 2 2 0 Zinc-binding zf-C2H2 PF00096.26 CCH62477.1 - 0.11 13.0 0.2 0.11 13.0 0.2 4.7 5 0 0 5 5 5 0 Zinc finger, C2H2 type SpoIIE PF07228.12 CCH62478.1 - 1.3e-27 96.9 0.0 1.9e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CCH62478.1 - 5.3e-06 26.3 0.2 0.06 13.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C HPIH PF13323.6 CCH62478.1 - 0.041 13.7 0.5 0.14 12.0 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain with HPIH motif HisG_C PF08029.11 CCH62479.1 - 0.018 15.2 0.4 3.3 7.9 0.1 2.6 1 1 1 2 2 2 0 HisG, C-terminal domain Peptidase_M1 PF01433.20 CCH62480.1 - 1.9e-69 233.6 0.4 3.6e-69 232.7 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCH62480.1 - 2.3e-45 155.1 7.1 3.2e-45 154.6 4.6 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CCH62480.1 - 1.6e-33 116.6 0.8 2.4e-33 116.0 0.8 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain SPA PF08616.10 CCH62480.1 - 0.0056 16.6 2.3 0.0065 16.4 0.1 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis CN_hydrolase PF00795.22 CCH62481.1 - 7.8e-44 150.0 0.0 1.1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CCH62481.1 - 1.7e-22 79.7 0.0 4.2e-22 78.4 0.0 1.5 1 1 0 1 1 1 1 NAD synthase PTPlike_phytase PF14566.6 CCH62481.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Nop10p PF04135.12 CCH62482.1 - 1.5e-22 79.4 1.0 1.7e-22 79.2 1.0 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ubiq-assoc PF09145.10 CCH62483.1 - 3.7e-23 81.2 2.7 9.7e-23 79.9 2.7 1.7 1 0 0 1 1 1 1 Ubiquitin-associated TPR_2 PF07719.17 CCH62483.1 - 0.00033 20.6 0.7 1.5 9.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCH62483.1 - 0.0011 18.7 5.8 2.1 8.3 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.31 CCH62483.1 - 0.02 15.0 0.1 0.067 13.3 0.1 1.9 1 0 0 1 1 1 0 DnaJ domain TPR_11 PF13414.6 CCH62483.1 - 0.049 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 CCH62483.1 - 0.072 13.4 0.1 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCH62483.1 - 0.12 12.4 0.0 0.71 10.0 0.0 2.2 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CENP-O PF09496.10 CCH62484.1 - 1.1e-11 45.1 1.0 2.8e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component SipA_VBS PF17985.1 CCH62484.1 - 0.018 14.9 0.2 0.045 13.6 0.2 1.7 1 0 0 1 1 1 0 SipA vinculin binding site SKA1 PF07160.12 CCH62484.1 - 0.24 11.2 5.6 0.49 10.2 5.6 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 NIF PF03031.18 CCH62485.1 - 4.3e-53 179.3 0.2 1.3e-52 177.7 0.2 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sof1 PF04158.14 CCH62486.1 - 3.1e-30 104.3 16.0 3.4e-29 100.9 17.5 2.0 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 CCH62486.1 - 5e-27 93.6 4.8 3.1e-06 27.8 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62486.1 - 9.1e-08 32.3 0.5 0.31 11.4 0.0 5.3 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCH62486.1 - 0.00049 19.2 0.4 0.21 10.5 0.1 3.5 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCH62486.1 - 0.013 14.9 0.1 0.035 13.4 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Abhydro_lipase PF04083.16 CCH62487.1 - 8.5e-12 44.5 0.0 1.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CCH62487.1 - 2.7e-08 33.8 0.0 5.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH62487.1 - 5.1e-06 25.9 0.0 8.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCH62487.1 - 0.003 18.2 0.0 0.0045 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 CCH62487.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PRP38_assoc PF12871.7 CCH62487.1 - 0.014 16.0 11.7 0.022 15.4 11.7 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAS_I_H PF18314.1 CCH62487.1 - 0.025 14.2 0.9 0.056 13.1 0.5 1.7 2 0 0 2 2 2 0 Fatty acid synthase type I helical domain FSH1 PF03959.13 CCH62487.1 - 0.056 13.1 0.3 1 9.0 0.1 2.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) RSRP PF17069.5 CCH62487.1 - 2.6 7.6 20.7 4.2 6.9 20.7 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Corona_nucleoca PF00937.18 CCH62487.1 - 4.4 6.2 12.8 6.7 5.6 12.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PUF PF00806.19 CCH62488.1 - 9.7e-59 191.9 20.6 1.4e-07 30.8 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.12 CCH62489.1 - 5.1e-21 75.1 4.8 6e-21 74.8 4.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.14 CCH62490.1 - 4.8e-64 215.5 2.7 4.8e-64 215.5 2.7 3.2 2 1 2 4 4 4 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CCH62490.1 - 3.7e-19 68.3 0.9 9.8e-19 67.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 CCH62490.1 - 0.014 15.8 0.1 0.076 13.4 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats Ca_bind_SSO6904 PF18249.1 CCH62490.1 - 5.1 7.5 7.6 5 7.5 0.3 3.6 4 0 0 4 4 4 0 Calcium binding protein SSO6904 DUF2870 PF11069.8 CCH62491.1 - 0.00018 21.8 2.5 0.00018 21.8 2.5 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF2870) DUF421 PF04239.12 CCH62491.1 - 0.023 14.4 1.0 0.023 14.4 1.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF421) Cnn_1N PF07989.11 CCH62491.1 - 3.9 7.7 13.3 3.4 7.9 5.3 3.1 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 MIP PF00230.20 CCH62492.1 - 2.1e-35 122.5 9.4 2.6e-35 122.2 9.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2273 PF10031.9 CCH62492.1 - 0.038 14.0 1.5 0.64 10.1 0.0 3.0 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) DUF1146 PF06612.11 CCH62492.1 - 0.09 12.8 2.0 1.8 8.7 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) tRNA-synt_1b PF00579.25 CCH62494.1 - 8e-78 261.7 0.0 1.1e-77 261.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.20 CCH62496.1 - 5.9e-16 58.4 15.7 5.9e-16 58.4 15.7 2.9 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CCH62496.1 - 0.00052 19.7 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 CCH62496.1 - 0.0018 18.6 1.4 0.0018 18.6 1.4 3.0 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 CCH62496.1 - 0.0055 17.0 0.2 0.0055 17.0 0.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCH62496.1 - 0.048 13.5 1.6 0.25 11.2 1.6 2.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AI-2E_transport PF01594.16 CCH62496.1 - 0.18 10.9 0.7 0.47 9.5 0.7 1.7 1 0 0 1 1 1 0 AI-2E family transporter zf-C3HC4 PF00097.25 CCH62496.1 - 0.95 9.4 9.0 0.023 14.6 1.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Tim10_DDP PF02953.15 CCH62497.1 - 2.7e-15 55.7 2.4 4.2e-15 55.1 2.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CCDC117 PF15810.5 CCH62497.1 - 0.019 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 Clat_adaptor_s PF01217.20 CCH62498.1 - 2.1e-55 186.5 3.5 2.6e-55 186.3 3.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain pP_pnuc_1 PF18165.1 CCH62498.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease SE PF08491.10 CCH62499.1 - 3.4e-111 370.7 0.2 4.6e-111 370.3 0.2 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CCH62499.1 - 1.1e-12 47.9 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCH62499.1 - 1.1e-05 25.2 0.0 7.8e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCH62499.1 - 0.00063 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCH62499.1 - 0.0033 16.6 0.3 0.0072 15.4 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 CCH62499.1 - 0.0037 17.2 0.2 0.006 16.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 CCH62499.1 - 0.019 15.5 0.1 0.061 13.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CCH62499.1 - 0.022 14.0 0.2 0.059 12.6 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCH62499.1 - 0.028 13.7 0.4 0.057 12.7 0.1 1.6 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 CCH62499.1 - 0.039 12.6 1.0 0.13 10.9 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 CCH62499.1 - 0.075 12.4 0.7 0.12 11.6 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.16 CCH62499.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 CCH62499.1 - 0.31 10.0 0.5 1.5 7.8 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein LsmAD PF06741.13 CCH62500.1 - 1.4e-28 99.2 0.2 1.4e-28 99.2 0.2 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CCH62500.1 - 1.1e-12 47.9 1.8 7.4e-12 45.2 0.1 3.0 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 CCH62500.1 - 0.007 16.4 0.3 0.018 15.1 0.3 1.8 1 1 0 1 1 1 1 Scd6-like Sm domain FerA PF08165.11 CCH62501.1 - 0.035 14.1 0.5 3.5 7.6 0.1 2.6 2 0 0 2 2 2 0 FerA (NUC095) domain RRF_GI PF12614.8 CCH62501.1 - 0.091 12.9 5.0 0.33 11.1 0.1 3.0 1 1 2 3 3 3 0 Ribosome recycling factor FKBP26_C PF18046.1 CCH62501.1 - 9.5 6.4 9.1 3.3 7.9 0.5 3.2 3 1 0 3 3 3 0 FKBP26_C-terminal Ribonuc_red_sm PF00268.21 CCH62502.1 - 1.7e-112 375.4 1.0 2.3e-112 375.0 1.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 CCH62502.1 - 0.13 13.1 0.1 0.37 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Ribonuc_red_sm PF00268.21 CCH62503.1 - 1.7e-78 263.9 11.2 2.1e-78 263.6 11.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Pox_F11 PF04943.12 CCH62503.1 - 0.079 12.0 1.1 0.11 11.5 0.5 1.5 1 1 1 2 2 2 0 Poxvirus F11 protein TAD2 PF18521.1 CCH62503.1 - 3.7 7.7 5.9 6.8 6.9 0.1 3.6 4 0 0 4 4 4 0 Transactivation domain 2 tRNA-synt_1g PF09334.11 CCH62504.1 - 1.2e-85 287.7 1.0 3.1e-83 279.7 1.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CCH62504.1 - 2.1e-18 66.0 0.3 1.2e-11 43.6 0.0 3.9 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CCH62504.1 - 3.8e-06 26.5 0.8 0.0018 17.7 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CCH62504.1 - 0.0005 19.1 0.0 0.00089 18.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) DNA_pol_E_B PF04042.16 CCH62505.1 - 1.1e-38 132.8 0.0 1.8e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CCH62505.1 - 1.6e-37 128.5 0.0 2.9e-37 127.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain PS_Dcarbxylase PF02666.15 CCH62506.1 - 2.6e-54 183.8 0.0 5.5e-54 182.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CCH62506.1 - 1.1e-15 57.7 0.3 4.1e-11 43.1 0.1 2.7 2 0 0 2 2 2 2 C2 domain MAJIN PF15077.6 CCH62507.1 - 0.68 9.7 11.0 0.78 9.5 11.0 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF3602 PF12223.8 CCH62507.1 - 1.8 9.2 7.4 25 5.6 7.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) DUF4407 PF14362.6 CCH62507.1 - 9.1 5.5 11.1 10 5.4 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Band_7 PF01145.25 CCH62508.1 - 2.6e-22 79.7 0.5 4.7e-22 78.8 0.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Spo12 PF05032.12 CCH62509.1 - 4.1e-17 61.8 0.4 4.1e-17 61.8 0.4 2.9 3 0 0 3 3 3 1 Spo12 family ATAD4 PF15321.6 CCH62509.1 - 0.72 11.2 4.9 8.9 7.7 4.9 2.4 1 1 0 1 1 1 0 ATPase family AAA domain containing 4 SMI1_KNR4 PF09346.10 CCH62510.1 - 4.1e-34 117.8 0.3 5.2e-33 114.3 0.0 2.6 2 1 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 CCH62510.1 - 0.16 12.4 4.2 0.21 12.0 0.0 3.2 3 2 0 3 3 3 0 SMI1-KNR4 cell-wall Lectin_C PF00059.21 CCH62511.1 - 0.02 15.6 0.9 0.38 11.5 0.1 2.9 3 0 0 3 3 3 0 Lectin C-type domain Pex24p PF06398.11 CCH62512.1 - 9.5e-23 80.8 10.1 1.4e-22 80.2 10.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Wzy_C PF04932.15 CCH62512.1 - 0.0082 15.8 2.0 0.051 13.2 0.4 2.1 2 0 0 2 2 2 1 O-Antigen ligase ELF PF03317.13 CCH62512.1 - 0.063 13.3 0.2 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 ELF protein DUF2207 PF09972.9 CCH62512.1 - 0.083 11.6 5.3 0.048 12.4 0.3 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Inhibitor_I29 PF08246.12 CCH62512.1 - 0.26 11.7 3.4 9.1 6.8 1.7 3.2 3 0 0 3 3 3 0 Cathepsin propeptide inhibitor domain (I29) PRT_C PF08372.10 CCH62512.1 - 0.33 10.7 2.3 1.4 8.7 0.1 2.6 2 1 1 3 3 3 0 Plant phosphoribosyltransferase C-terminal Ribosomal_S4 PF00163.19 CCH62513.1 - 3.2e-12 47.2 2.0 4.2e-12 46.8 1.5 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CCH62513.1 - 4.5e-12 45.5 0.0 8.8e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain DUF5065 PF16723.5 CCH62513.1 - 0.036 14.1 0.9 0.066 13.3 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) Ion_trans PF00520.31 CCH62514.1 - 6e-96 320.4 123.9 1.1e-35 123.0 6.3 5.2 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.12 CCH62514.1 - 0.0013 17.5 9.2 0.0013 17.5 9.2 7.1 6 1 1 7 7 7 4 Polycystin cation channel Gpi1 PF05024.15 CCH62515.1 - 3.5e-60 203.3 18.9 8.2e-60 202.1 18.9 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MRP-S33 PF08293.11 CCH62516.1 - 2.6e-30 104.5 0.5 3.2e-30 104.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribosomal_S2 PF00318.20 CCH62517.1 - 5.7e-24 84.6 3.4 1.7e-13 50.4 0.0 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 CCH62517.1 - 0.0036 18.6 13.5 0.0074 17.6 13.5 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus zf-ZPR1 PF03367.13 CCH62518.1 - 7.1e-114 377.0 12.9 1.4e-57 194.0 0.9 2.4 3 0 0 3 3 3 2 ZPR1 zinc-finger domain HypA PF01155.19 CCH62518.1 - 0.0027 17.7 4.4 0.63 10.1 1.2 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HEXIM PF15313.6 CCH62518.1 - 0.011 15.9 0.4 0.028 14.6 0.4 1.6 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DUF2294 PF10057.9 CCH62518.1 - 0.041 14.0 1.3 0.073 13.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) OrfB_Zn_ribbon PF07282.11 CCH62518.1 - 0.54 10.2 6.0 12 5.9 0.8 3.1 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.12 CCH62518.1 - 0.67 10.0 6.1 0.84 9.7 1.2 2.6 2 1 0 2 2 2 0 zinc-ribbons CpXC PF14353.6 CCH62518.1 - 1.9 8.6 7.6 2.4 8.2 0.0 3.5 2 1 1 3 3 3 0 CpXC protein zinc_ribbon_2 PF13240.6 CCH62518.1 - 2.1 8.2 17.6 1.9 8.3 0.5 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CCH62518.1 - 3.2 8.2 6.8 14 6.1 1.4 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 CCH62518.1 - 6.2 6.9 12.0 12 6.1 2.5 3.7 2 2 1 3 3 3 0 Double zinc ribbon CIAPIN1 PF05093.13 CCH62518.1 - 6.4 7.4 7.2 1.5 9.4 1.6 2.8 2 1 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ETF PF01012.21 CCH62519.1 - 6e-24 84.9 0.0 7.9e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF1548 PF07579.11 CCH62519.1 - 0.11 12.8 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) LSM PF01423.22 CCH62520.1 - 3.2e-05 23.5 0.3 0.00011 21.8 0.1 1.9 2 1 0 2 2 2 1 LSM domain 4HBT_3 PF13622.6 CCH62521.1 - 1.2e-25 91.2 0.0 1.4e-25 91.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CCH62521.1 - 5.3e-20 71.6 0.1 3.3e-15 56.1 0.1 3.1 2 1 1 3 3 3 3 Acyl-CoA thioesterase ILVD_EDD PF00920.21 CCH62522.1 - 2.8e-207 689.4 0.0 3.3e-207 689.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.32 CCH62523.1 - 1.5e-34 117.4 28.5 5.1e-07 30.3 0.1 12.0 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62523.1 - 4.5e-09 36.5 6.4 3.6 7.9 0.0 7.7 5 4 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain DUF3533 PF12051.8 CCH62525.1 - 1.4e-113 379.7 17.1 2.1e-113 379.1 17.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) SUI1 PF01253.22 CCH62526.1 - 4.3e-18 65.6 2.2 4.8e-18 65.5 1.3 1.6 1 1 0 1 1 1 1 Translation initiation factor SUI1 ACP PF06857.11 CCH62526.1 - 0.094 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) RNase_PH PF01138.21 CCH62527.1 - 4.3e-29 101.7 0.0 7.8e-29 100.8 0.0 1.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCH62527.1 - 1.3e-07 31.5 0.3 4.3e-07 29.9 0.2 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Gp_dh_C PF02800.20 CCH62529.1 - 1.9e-71 238.8 0.0 3.4e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCH62529.1 - 3e-38 130.2 0.0 8.1e-38 128.8 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCH62529.1 - 0.0045 17.1 1.1 0.009 16.1 0.3 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ThiJ_like PF17124.5 CCH62530.1 - 0.003 17.3 0.5 0.018 14.8 0.5 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 CCH62530.1 - 0.0043 16.9 0.0 0.023 14.5 0.0 2.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI PF01965.24 CCH62531.1 - 1.9e-07 31.0 0.0 1.8e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CCH62531.1 - 0.0038 16.9 0.1 0.043 13.5 0.1 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like PocR PF10114.9 CCH62531.1 - 0.031 14.1 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR RNA_pol_Rpb4 PF03874.16 CCH62532.1 - 1.3e-28 99.8 8.8 2.5e-28 98.9 8.8 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 OAF PF14941.6 CCH62532.1 - 0.069 12.6 0.1 0.27 10.6 0.0 1.7 1 1 0 2 2 2 0 Transcriptional regulator, Out at first HSF_DNA-bind PF00447.17 CCH62532.1 - 0.087 13.4 1.1 1.5 9.5 0.2 2.2 1 1 1 2 2 2 0 HSF-type DNA-binding Cpn60_TCP1 PF00118.24 CCH62533.1 - 1.4e-160 535.2 5.8 1.6e-160 535.0 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CCDC142 PF14923.6 CCH62533.1 - 0.11 11.2 0.1 7.5 5.2 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil protein 142 Sad1_UNC PF07738.13 CCH62535.1 - 9.6e-07 28.9 0.4 0.019 15.0 0.0 3.2 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Spore_YhaL PF14147.6 CCH62535.1 - 0.061 13.0 0.3 3.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL XhlA PF10779.9 CCH62535.1 - 0.74 10.1 3.1 4.2 7.7 0.1 2.9 2 1 0 2 2 2 0 Haemolysin XhlA TBCC_N PF16752.5 CCH62535.1 - 1.9 9.0 6.0 0.76 10.2 2.2 2.1 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Baculo_PEP_C PF04513.12 CCH62535.1 - 3.3 7.8 7.0 3.9 7.5 2.9 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CCH62535.1 - 3.7 8.1 8.0 2.2 8.8 2.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 CCH62535.1 - 7.8 6.6 9.3 1.1e+02 2.8 8.9 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF3445 PF11927.8 CCH62536.1 - 0.0034 17.1 0.9 0.0081 15.8 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3637 PF12337.8 CCH62536.1 - 0.048 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) DUF2457 PF10446.9 CCH62536.1 - 0.057 12.6 28.3 0.09 11.9 28.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_11 PF13720.6 CCH62536.1 - 3 8.4 8.4 15 6.1 1.1 2.8 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Tom37_C PF11801.8 CCH62537.1 - 1.1e-42 145.5 0.2 1.9e-42 144.7 0.2 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.9 CCH62537.1 - 2.9e-28 98.7 2.2 5.8e-28 97.7 2.2 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF4448 PF14610.6 CCH62538.1 - 2.3e-48 164.5 0.0 3.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Glyco_hydro_42M PF08532.10 CCH62538.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain ApoM PF11032.8 CCH62538.1 - 0.15 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 ApoM domain UPF0113_N PF17833.1 CCH62539.1 - 0.016 15.7 1.2 0.24 12.0 0.0 2.9 1 1 2 3 3 3 0 UPF0113 Pre-PUA domain DASH_Spc19 PF08287.11 CCH62539.1 - 0.07 13.0 6.1 0.16 11.9 6.1 1.6 1 0 0 1 1 1 0 Spc19 TrmE_N PF10396.9 CCH62540.1 - 3.4e-33 114.4 0.0 8.5e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 CCH62540.1 - 9.4e-29 101.0 5.4 1.4e-28 100.5 5.4 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 CCH62540.1 - 8.9e-22 77.3 1.9 8.9e-22 77.3 1.9 2.4 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH62540.1 - 4.6e-10 39.4 2.6 2.6e-08 33.7 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CCH62540.1 - 5.8e-10 38.9 4.0 1.4e-09 37.6 4.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCH62540.1 - 2.8e-09 37.1 1.4 0.00038 20.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Ras PF00071.22 CCH62540.1 - 4.1e-07 29.8 0.3 0.029 14.0 0.0 2.6 2 0 0 2 2 2 2 Ras family Dynamin_N PF00350.23 CCH62540.1 - 7.9e-05 22.8 0.2 7.9e-05 22.8 0.2 3.6 2 2 1 3 3 3 1 Dynamin family MMR_HSR1_Xtn PF16897.5 CCH62540.1 - 0.00014 21.9 0.6 0.00014 21.9 0.6 3.3 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain Roc PF08477.13 CCH62540.1 - 0.001 19.3 2.2 0.0043 17.3 0.0 2.7 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CCH62540.1 - 0.0094 15.4 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein PduV-EutP PF10662.9 CCH62540.1 - 0.03 14.1 4.1 2.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation EDR1 PF14381.6 CCH62540.1 - 0.044 13.5 3.0 0.18 11.5 0.4 2.3 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 Arf PF00025.21 CCH62540.1 - 0.06 12.8 7.4 0.27 10.7 0.1 3.4 3 1 1 4 4 4 0 ADP-ribosylation factor family DUF3760 PF12586.8 CCH62540.1 - 0.098 12.9 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) DUF2779 PF11074.8 CCH62540.1 - 0.35 11.3 3.2 0.67 10.4 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function(DUF2779) AAA_22 PF13401.6 CCH62540.1 - 0.9 9.8 2.8 16 5.8 0.0 3.7 2 2 0 3 3 3 0 AAA domain BLI1 PF17324.2 CCH62541.1 - 5.8e-26 91.3 10.3 6.6e-26 91.1 10.3 1.0 1 0 0 1 1 1 1 BLOC-1 interactor 1 BLOC1_2 PF10046.9 CCH62541.1 - 0.01 16.1 10.3 0.021 15.1 10.2 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Holin_BhlA PF10960.8 CCH62541.1 - 0.017 15.1 1.9 0.017 15.1 1.9 2.3 1 1 1 2 2 2 0 BhlA holin family ACCA PF03255.14 CCH62541.1 - 0.022 14.7 2.0 0.027 14.4 2.0 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2250 PF10007.9 CCH62541.1 - 0.039 14.1 1.0 0.052 13.7 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) FMP23 PF17315.2 CCH62541.1 - 0.048 13.8 1.1 0.048 13.8 1.1 1.8 1 1 1 2 2 2 0 Found in mitochondrial proteome Na_Ca_ex_C PF16494.5 CCH62541.1 - 0.069 13.6 3.7 0.073 13.5 2.1 1.7 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain DUF2536 PF10750.9 CCH62541.1 - 0.22 11.5 3.1 0.26 11.2 0.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2536) Glyco_hydro_76 PF03663.14 CCH62542.1 - 1.3e-157 525.1 24.5 1.4e-157 524.9 24.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CCH62542.1 - 0.028 13.5 14.4 0.035 13.2 0.4 3.0 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 CCH62543.1 - 4.3e-158 526.6 25.2 5.4e-158 526.3 25.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.14 CCH62544.1 - 4e-158 526.7 26.6 4.7e-158 526.5 26.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UQ_con PF00179.26 CCH62545.1 - 2.5e-48 163.3 0.0 2.8e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Tht1 PF04163.12 CCH62546.1 - 1.6e-32 113.0 33.2 1.6e-30 106.4 33.2 2.0 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Apolipoprotein PF01442.18 CCH62546.1 - 0.051 13.4 1.1 0.3 10.9 0.6 2.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain FliD_C PF07195.12 CCH62546.1 - 0.14 11.6 21.7 0.041 13.3 6.9 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Histidinol_dh PF00815.20 CCH62546.1 - 0.24 10.3 2.9 0.24 10.4 1.1 1.8 1 1 1 2 2 2 0 Histidinol dehydrogenase Salp15 PF12115.8 CCH62546.1 - 0.45 11.0 3.7 1.6 9.2 0.2 2.4 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF4164 PF13747.6 CCH62546.1 - 0.76 10.1 2.8 2.9 8.3 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF1664 PF07889.12 CCH62546.1 - 2.1 8.4 11.9 2.9 7.9 3.8 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CCH62546.1 - 9.2 6.3 33.5 0.28 11.2 9.4 3.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_primase_lrg PF04104.14 CCH62548.1 - 1.6e-75 253.9 0.0 2.9e-75 253.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Prp18 PF02840.15 CCH62548.1 - 0.031 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain p450 PF00067.22 CCH62549.1 - 7.5e-56 189.8 0.2 9.6e-56 189.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 T6PP_N PF18572.1 CCH62550.1 - 0.022 14.6 3.3 0.16 11.8 0.6 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Pex2_Pex12 PF04757.14 CCH62551.1 - 1.1e-40 139.6 15.6 1.4e-40 139.3 15.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCH62551.1 - 3e-06 27.0 7.2 4.7e-06 26.4 7.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH62551.1 - 0.0061 16.4 9.4 0.0095 15.8 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCH62551.1 - 0.021 15.0 10.7 0.04 14.1 10.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 CCH62551.1 - 0.086 12.7 1.0 13 5.8 0.1 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4 PF00097.25 CCH62551.1 - 0.27 11.2 9.5 0.46 10.4 9.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCH62551.1 - 0.52 10.7 9.0 0.88 10.0 9.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CCH62551.1 - 4.6 7.4 11.2 9.1 6.4 11.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger F_bP_aldolase PF01116.20 CCH62552.1 - 2.5e-87 292.9 0.1 2.8e-87 292.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MG4 PF17789.1 CCH62552.1 - 0.018 15.2 0.0 0.072 13.3 0.0 1.9 2 0 0 2 2 2 0 Macroglobulin domain MG4 DWNN PF08783.11 CCH62553.1 - 1.5e-29 102.1 2.5 7.3e-29 99.9 0.0 2.4 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 CCH62553.1 - 8e-08 32.0 5.3 1.5e-07 31.1 5.3 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 CCH62553.1 - 6e-06 26.4 0.2 1.6e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 CCH62553.1 - 6.8e-06 25.8 0.9 1.9e-05 24.4 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC PF00098.23 CCH62553.1 - 0.00091 19.2 2.2 0.0017 18.3 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 CCH62553.1 - 0.026 14.3 0.4 0.026 14.3 0.4 1.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Rubredoxin PF00301.20 CCH62553.1 - 0.13 12.3 1.8 22 5.2 0.1 3.0 3 0 0 3 3 3 0 Rubredoxin TF_Zn_Ribbon PF08271.12 CCH62553.1 - 0.24 10.9 2.8 0.3 10.6 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding TipE PF16972.5 CCH62553.1 - 2.6 7.2 9.6 5.2 6.1 9.6 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE zf-C3HC4_2 PF13923.6 CCH62553.1 - 4.7 7.1 6.8 0.53 10.2 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TFIIA_gamma_C PF02751.14 CCH62554.1 - 3.9e-24 84.5 0.5 5.4e-24 84.1 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CCH62554.1 - 2.1e-20 72.5 0.1 2.7e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Striatin PF08232.12 CCH62556.1 - 3.1e-19 70.1 0.6 3.1e-19 70.1 0.6 4.3 4 2 1 5 5 5 1 Striatin family ALP_N PF17989.1 CCH62556.1 - 0.2 11.8 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Actin like proteins N terminal domain TMEM51 PF15345.6 CCH62556.1 - 0.49 10.2 13.2 3 7.6 9.3 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 Alpha-amyl_C PF09071.10 CCH62556.1 - 0.49 10.3 2.6 0.58 10.0 0.1 2.5 3 0 0 3 3 3 0 Alpha-amylase, C terminal TCTP PF00838.17 CCH62557.1 - 3.4e-72 242.2 1.1 3.8e-72 242.0 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RcbX PF02341.15 CCH62557.1 - 0.2 12.0 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 RbcX protein CUE PF02845.16 CCH62558.1 - 1.6e-05 24.5 0.1 3.8e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.12 CCH62559.1 - 8.5e-27 93.2 5.6 9.9e-27 93.0 5.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 CCH62559.1 - 0.015 15.6 2.2 0.039 14.3 2.2 1.6 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 CCH62559.1 - 0.019 15.1 5.7 0.066 13.4 5.7 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 CCH62559.1 - 0.025 14.6 4.8 1 9.4 0.6 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 CCH62559.1 - 0.047 14.0 3.4 0.13 12.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Pet191_N PF10203.9 CCH62559.1 - 0.075 13.3 4.8 1.6 9.1 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DASH_Ask1 PF08655.10 CCH62560.1 - 3.5e-25 87.6 0.2 5.6e-25 87.0 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 GLE1 PF07817.13 CCH62560.1 - 0.066 12.4 0.2 0.11 11.7 0.2 1.3 1 0 0 1 1 1 0 GLE1-like protein SH3-RhoG_link PF16609.5 CCH62560.1 - 0.092 12.5 5.0 0.15 11.8 5.0 1.3 1 1 0 1 1 1 0 SH3-RhoGEF linking unstructured region Frag1 PF10277.9 CCH62561.1 - 1.2e-74 250.5 21.6 1.5e-74 250.3 21.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Collectrin PF16959.5 CCH62562.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Renal amino acid transporter SH3_2 PF07653.17 CCH62563.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCH62563.1 - 0.0044 16.6 0.0 0.0096 15.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH62563.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Actin PF00022.19 CCH62564.1 - 5.3e-23 81.3 0.4 1.4e-21 76.6 0.1 2.6 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.13 CCH62564.1 - 0.021 13.6 0.0 7.3 5.3 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein Peptidase_S24 PF00717.23 CCH62565.1 - 0.00034 20.5 0.1 0.0019 18.1 0.1 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CCH62565.1 - 0.0056 16.5 0.0 0.28 11.0 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Rhodanese PF00581.20 CCH62566.1 - 8.2e-10 39.2 0.0 1.6e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.26 CCH62567.1 - 1.5e-11 44.1 12.3 3e-06 27.4 3.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH62567.1 - 1.9e-08 34.4 11.2 0.0012 19.5 2.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCH62567.1 - 7e-07 29.4 16.6 5.9e-06 26.5 1.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCH62567.1 - 6.9e-06 26.2 9.8 0.0087 16.3 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCH62567.1 - 3e-05 24.2 6.0 0.015 15.6 1.6 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCH62567.1 - 0.0021 18.0 14.9 0.0049 16.8 3.5 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CCH62567.1 - 0.0026 18.0 1.9 0.0026 18.0 1.9 2.7 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2HE PF16278.5 CCH62567.1 - 0.081 13.4 0.4 0.081 13.4 0.4 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger GAGA PF09237.11 CCH62567.1 - 0.091 12.6 3.9 2.7 7.9 0.1 3.2 2 1 1 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.7 CCH62567.1 - 0.16 12.3 5.3 5 7.5 0.2 3.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-MYST PF17772.1 CCH62567.1 - 0.18 11.5 0.8 6.9 6.4 0.1 2.5 1 1 1 2 2 2 0 MYST family zinc finger domain Dynamin_M PF01031.20 CCH62569.1 - 1.2e-104 349.6 0.1 3.4e-104 348.1 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CCH62569.1 - 1.8e-55 187.6 0.4 4.1e-55 186.4 0.4 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CCH62569.1 - 5.5e-30 103.4 4.1 1.5e-29 102.0 4.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCH62569.1 - 0.00013 22.0 1.2 0.001 19.1 1.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CCH62569.1 - 0.021 14.6 0.2 0.051 13.4 0.2 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system HAT_KAT11 PF08214.11 CCH62571.1 - 1.9e-99 333.3 1.6 2.5e-99 332.9 1.6 1.0 1 0 0 1 1 1 1 Histone acetylation protein Sfi1_C PF10638.9 CCH62572.1 - 9.3e-13 48.8 1.9 9.3e-13 48.8 1.9 3.1 3 0 0 3 3 3 1 Spindle body associated protein C-terminus Sfi1 PF08457.10 CCH62572.1 - 1.5e-12 46.9 66.7 7.3e-09 34.7 56.0 4.5 1 1 2 3 3 3 3 Sfi1 spindle body protein Nsp1_C PF05064.13 CCH62573.1 - 3.3e-40 136.5 5.5 3.3e-40 136.5 5.5 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CCH62573.1 - 6.6e-12 46.1 85.0 2.6e-08 34.6 30.0 10.0 1 1 5 6 6 6 2 Nucleoporin FG repeat region PRP9_N PF16958.5 CCH62573.1 - 0.38 10.8 6.9 0.86 9.6 6.3 2.0 1 1 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF1664 PF07889.12 CCH62573.1 - 1.4 8.9 5.9 0.85 9.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CCH62573.1 - 2 9.0 12.0 2.9 8.4 10.9 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 CCH62573.1 - 3.8 8.1 8.9 2.6 8.6 1.4 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GCS PF03074.16 CCH62574.1 - 2.3e-150 501.0 0.0 3e-150 500.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GTP_EFTU PF00009.27 CCH62575.1 - 3.9e-58 196.2 0.0 6.7e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CCH62575.1 - 9.4e-24 83.3 0.0 2.8e-23 81.8 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCH62575.1 - 1.2e-17 63.7 0.3 6.4e-10 38.9 0.0 3.1 3 0 0 3 3 3 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCH62575.1 - 1.6e-06 28.4 0.3 3.4e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.10 CCH62575.1 - 0.035 13.5 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CT_C_D PF02682.16 CCH62575.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D zf-C2HC5 PF06221.13 CCH62576.1 - 1.1e-21 76.5 6.2 2e-21 75.7 6.2 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-C2H2_aberr PF17017.5 CCH62576.1 - 4 7.5 8.6 2.7 8.1 4.1 2.4 1 1 1 2 2 2 0 Aberrant zinc-finger PHD PF00628.29 CCH62578.1 - 0.018 14.9 11.0 0.11 12.4 11.0 2.3 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CCH62578.1 - 0.21 11.5 4.6 0.66 10.0 4.6 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Pkinase PF00069.25 CCH62579.1 - 7.1e-55 186.2 1.6 2.4e-53 181.2 0.5 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62579.1 - 1.7e-28 99.6 1.6 2.8e-26 92.4 0.6 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase BP28CT PF08146.12 CCH62580.1 - 2.2e-34 118.6 2.2 2.2e-34 118.6 2.2 3.2 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CCH62580.1 - 8.1e-17 61.6 1.4 8.1e-17 61.6 1.4 6.2 6 1 0 6 6 6 2 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 CCH62580.1 - 0.034 14.5 0.0 7.4 7.0 0.0 4.0 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 CCH62580.1 - 0.035 14.6 0.1 6 7.5 0.1 3.2 2 0 0 2 2 2 0 HEAT-like repeat DUF3385 PF11865.8 CCH62580.1 - 0.042 13.8 16.7 0.33 10.9 1.8 6.4 6 1 0 6 6 6 0 Domain of unknown function (DUF3385) VPS9 PF02204.18 CCH62580.1 - 0.084 13.1 8.3 0.31 11.3 1.4 4.7 4 1 0 4 4 4 0 Vacuolar sorting protein 9 (VPS9) domain UNC-50 PF05216.13 CCH62581.1 - 1.4e-85 286.4 23.3 1.6e-85 286.2 23.3 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.22 CCH62582.1 - 3.3e-16 58.7 1.6 5.1e-08 32.8 0.2 3.2 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CCH62582.1 - 8.9e-08 32.1 0.1 1.5e-05 24.9 0.0 4.3 3 2 0 3 3 3 2 PLD-like domain PX PF00787.24 CCH62582.1 - 6.9e-05 22.8 9.5 0.00055 19.9 0.4 4.7 5 0 0 5 5 5 2 PX domain GATA PF00320.27 CCH62584.1 - 1e-13 50.6 3.5 1e-13 50.6 3.5 1.8 2 0 0 2 2 2 1 GATA zinc finger Nudix_N_2 PF14803.6 CCH62584.1 - 0.13 12.2 1.5 0.74 9.8 0.3 2.3 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 CCH62584.1 - 0.18 11.3 0.4 0.28 10.7 0.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding FSA_C PF10479.9 CCH62584.1 - 3.7 5.6 9.1 4.4 5.3 9.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Snf7 PF03357.21 CCH62586.1 - 1.9e-09 37.3 21.1 1.9e-09 37.3 21.1 1.3 1 1 0 1 1 1 1 Snf7 IBN_N PF03810.19 CCH62586.1 - 0.024 14.6 1.7 0.056 13.4 1.7 1.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain PNPase PF03726.14 CCH62586.1 - 0.16 12.4 7.9 0.11 12.9 1.7 2.5 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF3496 PF12001.8 CCH62586.1 - 0.26 11.7 9.6 0.57 10.6 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Laps PF10169.9 CCH62586.1 - 7.1 7.2 17.1 0.17 12.5 8.6 2.3 1 1 1 2 2 2 0 Learning-associated protein WD40 PF00400.32 CCH62587.1 - 3.9e-19 68.6 8.7 0.00016 22.4 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62587.1 - 0.00057 20.1 5.3 0.048 14.0 0.0 4.8 4 2 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain FapA PF03961.13 CCH62587.1 - 7.6 5.0 16.6 34 2.9 13.7 2.4 2 1 0 2 2 2 0 Flagellar Assembly Protein A DASH_Spc34 PF08657.10 CCH62588.1 - 6e-78 262.2 8.6 6.9e-78 262.0 8.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 eIF-4B PF06273.11 CCH62588.1 - 0.18 10.8 2.0 0.32 10.0 2.0 1.4 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DASH_Spc19 PF08287.11 CCH62588.1 - 3.3 7.6 9.8 1.4 8.8 3.2 2.7 2 1 0 2 2 2 0 Spc19 PIR PF00399.19 CCH62589.1 - 7.8e-14 50.8 24.1 9.2e-07 28.3 8.0 3.9 3 0 0 3 3 3 3 Yeast PIR protein repeat DUF4942 PF13708.6 CCH62589.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) Mucin PF01456.17 CCH62589.1 - 0.84 9.6 19.4 1.5 8.8 19.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PIR PF00399.19 CCH62591.1 - 2.7e-34 116.0 50.5 3.9e-09 35.8 3.5 5.0 4 0 0 4 4 4 4 Yeast PIR protein repeat DUF4942 PF13708.6 CCH62591.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) MRP-S28 PF10213.9 CCH62592.1 - 2e-33 115.5 0.1 3e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ada3 PF10198.9 CCH62593.1 - 1.3e-39 135.3 6.0 5.7e-39 133.3 6.0 2.2 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF968 PF06147.11 CCH62593.1 - 0.68 10.2 4.3 0.25 11.6 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF968) UQ_con PF00179.26 CCH62594.1 - 8.3e-45 151.9 0.0 1.1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CCH62594.1 - 5e-27 93.5 2.2 1e-26 92.5 2.2 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Calsarcin PF05556.11 CCH62594.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) DUF1421 PF07223.11 CCH62594.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) PXA PF02194.15 CCH62595.1 - 1.9e-14 54.1 0.8 4e-14 53.0 0.5 2.0 2 1 0 2 2 2 1 PXA domain Syja_N PF02383.18 CCH62595.1 - 0.38 10.0 3.6 0.69 9.2 3.6 1.4 1 0 0 1 1 1 0 SacI homology domain PseudoU_synth_2 PF00849.22 CCH62596.1 - 1.6e-17 64.0 0.2 5e-16 59.2 0.2 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase Nipped-B_C PF12830.7 CCH62597.1 - 2.2e-38 132.1 1.9 1.6e-37 129.3 0.5 2.8 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CCH62597.1 - 7.5e-13 48.5 0.3 1.4e-09 38.1 0.9 3.1 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion PWI PF01480.17 CCH62597.1 - 0.024 14.9 2.5 0.23 11.8 0.3 3.7 3 0 0 3 3 3 0 PWI domain TAF6_C PF07571.13 CCH62597.1 - 0.19 12.1 1.5 0.87 10.0 0.1 3.0 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Metallophos PF00149.28 CCH62598.1 - 2.4e-13 51.0 2.4 3.8e-13 50.4 2.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UreD PF01774.17 CCH62598.1 - 0.097 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 UreD urease accessory protein ubiquitin PF00240.23 CCH62599.1 - 4.3e-34 116.1 0.6 7.7e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CCH62599.1 - 5.2e-23 80.9 3.0 1.2e-22 79.8 3.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CCH62599.1 - 4.7e-16 58.4 0.7 4.7e-16 58.4 0.7 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCH62599.1 - 2.5e-05 24.6 0.2 0.00012 22.4 0.1 2.0 2 1 0 2 2 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCH62599.1 - 0.0013 18.8 0.3 0.0037 17.3 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCH62599.1 - 0.0033 17.8 0.2 0.0077 16.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCH62599.1 - 0.0051 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CCH62599.1 - 0.017 15.7 0.3 0.023 15.3 0.3 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CCH62599.1 - 0.02 14.9 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Fer2_3 PF13085.6 CCH62599.1 - 0.055 13.5 0.3 0.096 12.7 0.3 1.5 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Sde2_N_Ubi PF13019.6 CCH62599.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Sec1 PF00995.23 CCH62601.1 - 6.8e-114 382.2 21.4 7.9e-114 382.0 21.4 1.0 1 0 0 1 1 1 1 Sec1 family APP_E2 PF12925.7 CCH62601.1 - 0.066 12.9 0.3 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein LZ3wCH PF18517.1 CCH62601.1 - 1.6 8.9 6.0 0.61 10.2 1.6 2.4 2 0 0 2 2 2 0 Leucine zipper with capping helix domain DUF2115 PF09888.9 CCH62601.1 - 3.8 8.0 6.2 1.1 9.7 1.7 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) SIR2 PF02146.17 CCH62602.1 - 2.9e-30 105.5 0.0 6.6e-30 104.3 0.0 1.6 1 1 0 1 1 1 1 Sir2 family RED_N PF07808.13 CCH62602.1 - 0.00021 20.9 0.4 0.00044 19.9 0.4 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region Peptidase_C71 PF12386.8 CCH62602.1 - 0.033 13.8 0.4 3.2 7.4 0.0 3.3 3 1 1 4 4 4 0 Pseudomurein endo-isopeptidase Pei ATP_bind_1 PF03029.17 CCH62603.1 - 1.5e-88 296.7 0.0 1.7e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CCH62603.1 - 0.00086 18.4 0.1 0.0022 17.0 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CCH62603.1 - 0.0016 18.4 0.2 0.031 14.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CCH62603.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.1 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CCH62603.1 - 0.0033 17.9 0.1 0.0097 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 CCH62603.1 - 0.0034 17.2 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RNA_helicase PF00910.22 CCH62603.1 - 0.0037 17.6 0.0 0.025 15.0 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_10 PF12846.7 CCH62603.1 - 0.0045 16.0 0.0 0.0073 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.27 CCH62603.1 - 0.011 16.3 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CCH62603.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCH62603.1 - 0.013 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.27 CCH62603.1 - 0.013 15.1 0.0 0.37 10.3 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 CCH62603.1 - 0.016 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 CCH62603.1 - 0.026 14.8 0.0 0.06 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCH62603.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CCH62603.1 - 0.039 13.7 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 CCH62603.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 CCH62603.1 - 0.048 14.0 0.1 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CCH62603.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CCH62603.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CCH62603.1 - 0.061 12.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CCH62603.1 - 0.066 13.6 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 CCH62603.1 - 0.067 12.4 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.18 CCH62603.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 CCH62603.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_14 PF13173.6 CCH62603.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CCH62603.1 - 0.14 11.5 0.1 1.3 8.4 0.0 2.4 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region NACHT PF05729.12 CCH62603.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 CCH62603.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.23 CCH62603.1 - 0.17 11.9 0.0 0.43 10.6 0.0 1.7 2 0 0 2 2 1 0 Dynamin family Viral_helicase1 PF01443.18 CCH62603.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RSN1_7TM PF02714.15 CCH62604.1 - 3.7e-80 269.2 24.5 3.7e-80 269.2 24.5 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCH62604.1 - 3.5e-39 134.1 1.4 3.5e-39 134.1 1.4 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCH62604.1 - 4.3e-33 115.0 0.0 1e-32 113.8 0.0 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF3930 PF13067.6 CCH62604.1 - 0.075 13.3 0.4 0.32 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) NAD_binding_6 PF08030.12 CCH62604.1 - 0.16 12.1 0.6 0.32 11.1 0.6 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DEAD PF00270.29 CCH62605.1 - 1.2e-39 135.9 0.1 2.5e-39 134.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH62605.1 - 5.1e-24 84.7 0.1 3.4e-23 82.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH62605.1 - 9.7e-06 25.7 0.0 4e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCH62605.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 CCH62606.1 - 1.4e-63 213.8 0.0 1.9e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CCH62606.1 - 0.00068 20.2 0.1 0.0042 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCH62606.1 - 0.0023 18.2 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CCH62606.1 - 0.0034 17.2 0.0 0.025 14.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SKI PF01202.22 CCH62606.1 - 0.0066 16.6 0.0 0.081 13.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 CCH62606.1 - 0.0076 16.4 0.0 0.02 15.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain ALC PF17527.2 CCH62606.1 - 0.012 15.3 0.4 0.027 14.1 0.4 1.6 1 0 0 1 1 1 0 Phage ALC protein AAA_17 PF13207.6 CCH62606.1 - 0.014 15.8 0.1 0.037 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain TetR_C_19 PF17924.1 CCH62606.1 - 0.12 13.0 1.1 0.2 12.3 0.5 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ApbA_C PF08546.11 CCH62607.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal FHA PF00498.26 CCH62608.1 - 4.2e-17 62.2 0.2 1.4e-16 60.6 0.2 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCH62608.1 - 1.1e-05 25.7 0.1 4.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF4321 PF14209.6 CCH62608.1 - 0.068 13.0 1.7 0.14 12.0 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) Exonuc_VII_L PF02601.15 CCH62608.1 - 1.2 8.6 9.0 1.6 8.2 9.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4337 PF14235.6 CCH62608.1 - 4.3 7.4 12.7 10 6.2 12.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 CCH62608.1 - 6.2 6.1 9.1 10 5.3 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cation_efflux PF01545.21 CCH62609.1 - 2.5e-44 151.4 13.4 2.5e-44 151.4 13.4 2.7 3 1 0 3 3 3 1 Cation efflux family GWT1 PF06423.12 CCH62609.1 - 3.2 7.9 11.5 6.7 6.8 3.9 3.1 2 1 1 3 3 3 0 GWT1 SelP_N PF04592.14 CCH62609.1 - 8 5.8 22.0 3.5 6.9 1.9 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Topoisom_bac PF01131.20 CCH62610.1 - 1.2e-100 337.4 0.0 1.7e-99 333.6 0.0 2.0 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CCH62610.1 - 7.6e-21 74.3 0.0 1.6e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain EST1_DNA_bind PF10373.9 CCH62611.1 - 5e-53 180.4 10.4 5e-53 180.4 10.4 2.9 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CCH62611.1 - 4.4e-23 82.4 2.6 4.4e-23 82.4 2.6 4.5 4 2 0 4 4 4 1 Telomerase activating protein Est1 BUD22 PF09073.10 CCH62611.1 - 4.9 6.4 19.8 9.2 5.5 19.2 1.7 1 1 0 1 1 1 0 BUD22 PIP5K PF01504.18 CCH62612.1 - 6.4e-91 304.4 2.0 6.4e-91 304.4 2.0 3.0 4 0 0 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase W2 PF02020.18 CCH62613.1 - 1.4e-16 60.4 4.7 1.4e-16 60.4 4.7 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CCH62613.1 - 1.7e-12 46.5 23.8 4.9e-05 22.9 11.5 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CCH62613.1 - 2.2e-09 37.3 0.0 4.7e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 CCH62613.1 - 0.00071 17.8 1.6 0.00071 17.8 1.6 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CCH62613.1 - 0.0011 18.0 7.1 0.0049 15.9 7.0 1.9 1 1 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 CCH62613.1 - 0.01 16.2 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain CTP_transf_3 PF02348.19 CCH62613.1 - 0.038 13.9 0.6 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Cytidylyltransferase Hexapep_2 PF14602.6 CCH62613.1 - 8.5 6.2 23.6 0.87 9.4 5.5 3.7 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Ras PF00071.22 CCH62614.1 - 5.4e-51 172.4 0.0 6.3e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH62614.1 - 7.9e-19 68.1 0.0 1.1e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH62614.1 - 8.1e-08 31.9 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Anp1 PF03452.14 CCH62615.1 - 4.9e-107 357.2 0.1 6e-107 357.0 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CCH62615.1 - 0.004 17.0 0.0 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Alk_phosphatase PF00245.20 CCH62616.1 - 7.3e-123 410.6 0.0 9.1e-123 410.3 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CCH62616.1 - 2.6e-06 27.0 0.0 8.2e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily GP41 PF00517.17 CCH62616.1 - 0.35 10.7 2.3 0.3 10.9 0.6 1.7 2 0 0 2 2 2 0 Retroviral envelope protein cwf21 PF08312.12 CCH62617.1 - 2.2e-11 43.7 1.5 2.2e-11 43.7 1.5 1.8 1 1 1 2 2 2 1 cwf21 domain PAD PF03068.15 CCH62617.1 - 0.014 14.4 1.4 0.016 14.2 1.4 1.0 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) TSP_C PF05735.12 CCH62617.1 - 0.068 13.1 0.5 0.094 12.6 0.5 1.2 1 0 0 1 1 1 0 Thrombospondin C-terminal region Ribosomal_L28 PF00830.19 CCH62617.1 - 2.4 8.4 6.9 0.91 9.8 3.5 2.1 2 1 0 2 2 2 0 Ribosomal L28 family Glyco_transf_15 PF01793.16 CCH62618.1 - 1.3e-101 340.1 5.3 1.7e-101 339.7 5.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TPR_1 PF00515.28 CCH62619.1 - 2.4e-15 55.6 3.1 5.6e-05 22.8 0.6 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62619.1 - 1.2e-09 37.5 1.3 0.035 14.2 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62619.1 - 4.2e-06 26.5 2.9 0.69 10.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62619.1 - 0.00011 21.8 1.2 0.18 11.5 0.1 3.2 2 1 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 CCH62619.1 - 0.003 17.8 0.3 4.5 7.6 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCH62619.1 - 0.0047 17.0 1.1 0.27 11.3 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CCH62619.1 - 0.034 14.4 2.9 0.18 12.1 2.1 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 INCENP_ARK-bind PF03941.15 CCH62620.1 - 9.5e-12 44.7 0.3 2.2e-11 43.5 0.3 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region LPD38 PF18857.1 CCH62620.1 - 0.0036 17.5 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 Large polyvalent protein associated domain 38 Methyltransf_19 PF04672.12 CCH62620.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl methyltransferase F-box PF00646.33 CCH62622.1 - 0.00044 20.1 0.1 0.0016 18.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CCH62622.1 - 0.0028 17.5 0.6 0.0064 16.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 CCH62622.1 - 0.076 13.5 0.6 0.076 13.5 0.6 7.6 5 2 3 8 8 8 0 Leucine Rich repeats (2 copies) Lge1 PF11488.8 CCH62623.1 - 1.5e-21 76.4 3.7 3.4e-21 75.2 3.7 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.25 CCH62624.1 - 1.1e-32 113.1 0.1 1.4e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCH62624.1 - 2.1e-18 66.7 0.0 2.8e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCH62624.1 - 2.2e-05 24.5 0.0 7.2e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 KR domain T_Ag_DNA_bind PF02217.16 CCH62624.1 - 0.047 14.3 0.4 1.2 9.8 0.1 2.8 3 0 0 3 3 3 0 Origin of replication binding protein Pkinase PF00069.25 CCH62625.1 - 3.1e-73 246.4 0.0 3.5e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62625.1 - 1.3e-32 113.2 0.0 1.6e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCH62625.1 - 2.8e-05 23.6 0.0 4.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCH62625.1 - 0.0016 17.5 0.1 0.011 14.8 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCH62625.1 - 0.0076 16.2 0.2 0.053 13.4 0.2 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCH62625.1 - 0.0095 15.3 0.2 0.037 13.4 0.2 1.9 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.15 CCH62626.1 - 1.1e-21 77.2 0.3 2.9e-21 75.9 0.3 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif 7TM_GPCR_Srh PF10318.9 CCH62626.1 - 0.0019 17.3 1.4 0.0033 16.5 1.4 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF5357 PF17310.2 CCH62626.1 - 0.041 12.4 0.1 0.066 11.8 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Ecl1 PF12855.7 CCH62626.1 - 0.11 13.7 4.5 0.24 12.5 4.5 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins DUF2401 PF10287.9 CCH62627.1 - 6.8e-95 317.0 0.4 6.8e-95 317.0 0.4 1.6 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCH62627.1 - 9.3e-31 106.1 0.2 2.3e-30 104.8 0.2 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SOG2 PF10428.9 CCH62627.1 - 0.26 10.5 9.0 0.33 10.1 9.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.10 CCH62627.1 - 0.48 10.1 12.3 0.78 9.4 12.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 ABC2_membrane PF01061.24 CCH62628.1 - 9.7e-66 221.2 45.0 2.4e-35 121.9 11.0 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCH62628.1 - 8e-37 126.8 0.0 2.4e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCH62628.1 - 8e-33 112.2 7.4 2.4e-28 97.8 0.2 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCH62628.1 - 1.9e-10 41.2 0.0 4.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCH62628.1 - 7.2e-08 32.5 0.0 6.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCH62628.1 - 2.9e-05 24.5 0.5 0.0076 16.6 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCH62628.1 - 0.00012 22.1 0.3 0.75 9.9 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CCH62628.1 - 0.00017 21.9 0.1 0.085 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCH62628.1 - 0.00054 19.9 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.6 CCH62628.1 - 0.00076 19.2 0.5 0.099 12.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCH62628.1 - 0.0022 18.5 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCH62628.1 - 0.0023 17.8 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH62628.1 - 0.0027 17.2 0.0 4.4 6.7 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CCH62628.1 - 0.003 17.3 0.3 0.71 9.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CCH62628.1 - 0.0034 16.6 5.2 0.0034 16.6 5.2 3.5 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.6 CCH62628.1 - 0.0084 15.7 0.0 0.3 10.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CCH62628.1 - 0.011 15.3 0.4 0.7 9.5 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CCH62628.1 - 0.015 15.6 0.0 2.2 8.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 CCH62628.1 - 0.027 14.4 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CCH62628.1 - 0.032 13.5 0.2 2.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Poxvirus PF06227.12 CCH62628.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 dsDNA Poxvirus TsaE PF02367.17 CCH62628.1 - 0.043 13.8 0.3 0.17 11.9 0.2 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CCH62628.1 - 0.069 12.3 0.6 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 CCH62628.1 - 0.08 13.1 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CCH62628.1 - 0.098 12.9 0.1 24 5.2 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 CCH62628.1 - 0.099 12.4 0.3 2 8.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCH62628.1 - 0.12 12.3 0.2 22 4.9 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 CCH62628.1 - 0.24 11.9 0.6 0.51 10.8 0.1 1.8 2 0 0 2 2 1 0 AAA domain Exo5 PF09810.9 CCH62629.1 - 2.9e-57 194.8 0.2 4.3e-57 194.3 0.2 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 CCH62629.1 - 0.00071 19.6 4.5 1.3 8.9 3.0 3.1 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 CCH62629.1 - 4.7 7.3 6.3 12 5.9 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function DUF83 Exo5 PF09810.9 CCH62630.1 - 2.1e-11 44.0 0.0 3.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Glutaredoxin PF00462.24 CCH62631.1 - 2.4e-17 62.9 0.0 3.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin FTR1 PF03239.14 CCH62632.1 - 2.2e-95 319.4 0.0 1.1e-93 313.8 0.0 2.0 1 1 0 1 1 1 1 Iron permease FTR1 family DUF2207 PF09972.9 CCH62632.1 - 0.04 12.7 0.0 0.04 12.7 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Amidase_5 PF05382.13 CCH62632.1 - 1.9 8.4 5.6 0.15 11.9 0.4 1.8 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase CorA PF01544.18 CCH62633.1 - 0.00079 18.8 6.0 0.00079 18.8 6.0 2.8 2 2 1 3 3 3 1 CorA-like Mg2+ transporter protein SapB_1 PF05184.15 CCH62633.1 - 0.25 11.4 3.5 4.9 7.3 1.0 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 Glyco_transf_15 PF01793.16 CCH62634.1 - 4.5e-114 381.1 8.9 5.9e-114 380.7 8.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Abhydrolase_1 PF00561.20 CCH62635.1 - 7.4e-19 68.4 0.0 1.2e-18 67.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCH62635.1 - 2.6e-11 44.6 0.0 3.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCH62635.1 - 4.7e-11 42.4 0.0 1.4e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CCH62635.1 - 9e-07 28.7 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CCH62635.1 - 0.00025 20.9 0.0 0.00045 20.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase DUF900 PF05990.12 CCH62635.1 - 0.0011 18.6 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 CCH62635.1 - 0.0011 18.7 0.0 0.0052 16.5 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein DUF1749 PF08538.10 CCH62635.1 - 0.0028 16.8 0.1 0.59 9.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.7 CCH62635.1 - 0.0064 15.4 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.15 CCH62635.1 - 0.0083 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 CCH62635.1 - 0.14 11.4 0.1 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 CCH62635.1 - 0.24 11.2 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3605 PF12239.8 CCH62637.1 - 1.2e-38 132.9 1.5 1.4e-38 132.6 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) VPS9 PF02204.18 CCH62639.1 - 3.5e-16 59.3 2.5 7.5e-16 58.2 2.5 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain s48_45 PF07422.13 CCH62639.1 - 7.7 7.1 10.0 0.36 11.4 2.3 2.9 2 1 0 2 2 2 0 Sexual stage antigen s48/45 domain ISP1_C PF18161.1 CCH62640.1 - 0.035 14.1 0.4 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 ISP1 C-terminal SH3_1 PF00018.28 CCH62641.1 - 1.3e-17 63.1 0.0 8.3e-10 38.1 0.0 3.2 3 0 0 3 3 3 2 SH3 domain PX PF00787.24 CCH62641.1 - 9.8e-17 61.0 0.0 2.1e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 CCH62641.1 - 2.2e-10 40.3 0.0 0.00057 19.7 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CCH62641.1 - 2.5e-07 30.3 0.0 4.6e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.24 CCH62641.1 - 0.00032 20.6 0.1 0.00086 19.2 0.1 1.7 1 0 0 1 1 1 1 PB1 domain UCH PF00443.29 CCH62642.1 - 2.9e-33 115.5 1.3 3.8e-33 115.1 1.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sec34 PF04136.15 CCH62642.1 - 0.028 14.3 0.8 1.1 9.2 0.0 3.0 3 0 0 3 3 3 0 Sec34-like family GCR1_C PF12550.8 CCH62643.1 - 0.00063 20.0 0.4 0.025 14.9 0.4 2.8 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Mitofilin PF09731.9 CCH62643.1 - 0.98 8.2 6.7 1.8 7.3 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.32 CCH62644.1 - 1.7e-51 171.1 20.7 2.5e-09 37.6 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CCH62644.1 - 8e-40 136.1 1.6 1.5e-39 135.2 1.6 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CCH62644.1 - 4.1e-12 46.2 0.0 0.032 14.5 0.0 6.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CCH62644.1 - 8.7e-07 28.7 0.1 2.2e-06 27.4 0.1 1.8 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 CCH62644.1 - 2.7e-05 23.6 0.0 0.59 9.4 0.0 3.6 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 CCH62644.1 - 5.6e-05 22.3 0.0 0.1 11.5 0.0 3.7 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CCH62644.1 - 0.0024 16.5 0.3 0.25 9.8 0.1 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain nos_propeller PF18764.1 CCH62644.1 - 0.0025 17.7 0.1 4.6 7.2 0.0 3.4 3 0 0 3 3 3 2 Nitrous oxide reductase propeller repeat DUF5570 PF17731.1 CCH62644.1 - 0.099 12.7 1.0 0.34 11.0 0.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5570) DUF5315 PF17242.2 CCH62645.1 - 4.3e-21 74.5 0.6 4.3e-21 74.5 0.6 1.7 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Mei5 PF10376.9 CCH62645.1 - 8.5 6.2 12.8 6.1 6.7 0.5 2.2 1 1 0 2 2 2 0 Double-strand recombination repair protein PGI PF00342.19 CCH62646.1 - 4.2e-245 813.9 2.8 4.9e-245 813.7 2.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Lipoprotein_18 PF06804.11 CCH62646.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 NlpB/DapX lipoprotein CAF1C_H4-bd PF12265.8 CCH62647.1 - 2.1e-19 69.5 3.4 2.8e-18 65.9 1.5 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCH62647.1 - 7.3e-15 55.1 10.8 0.0013 19.5 0.7 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62647.1 - 1.7e-05 25.0 3.7 0.17 12.2 0.2 4.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mt_ATP-synt_B PF05405.14 CCH62648.1 - 1e-48 165.0 5.9 1.5e-48 164.5 5.9 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2605 PF10792.9 CCH62648.1 - 0.0066 16.3 0.4 0.017 15.0 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2605) RRP36 PF06102.12 CCH62648.1 - 0.16 11.9 2.2 0.26 11.2 2.2 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Med8 PF10232.9 CCH62649.1 - 5.1e-12 45.9 0.2 6.7e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 HCV_core PF01542.18 CCH62649.1 - 0.06 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus core protein Rogdi_lz PF10259.9 CCH62649.1 - 0.11 11.9 1.6 0.15 11.5 1.6 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF3535 PF12054.8 CCH62650.1 - 3e-116 389.2 2.2 3e-116 389.2 2.2 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CCH62650.1 - 7.5e-66 222.2 0.1 1.6e-65 221.1 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCH62650.1 - 1.8e-19 70.1 0.0 1.5e-18 67.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 CCH62650.1 - 2.6e-13 49.0 0.3 0.56 10.6 0.0 8.0 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.7 CCH62650.1 - 1e-08 35.7 1.8 0.57 10.8 0.1 6.5 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 CCH62650.1 - 4.6e-06 26.9 0.1 1.8 8.9 0.0 5.1 4 1 1 5 5 5 2 TAF6 C-terminal HEAT repeat domain ResIII PF04851.15 CCH62650.1 - 9.5e-06 25.7 0.1 7.5e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HEAT_EZ PF13513.6 CCH62650.1 - 9.6e-06 26.0 1.5 0.43 11.1 0.1 5.6 6 0 0 6 6 6 2 HEAT-like repeat UME PF08064.13 CCH62650.1 - 0.0027 17.6 0.9 51 3.9 0.0 5.7 5 1 1 6 6 6 0 UME (NUC010) domain GUN4_N PF16416.5 CCH62650.1 - 0.0078 16.2 0.7 0.39 10.7 0.0 3.2 2 0 0 2 2 2 1 ARM-like repeat domain, GUN4-N terminal ERCC3_RAD25_C PF16203.5 CCH62650.1 - 0.022 14.0 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Condensin2nSMC PF12422.8 CCH62650.1 - 0.32 11.2 2.0 31 4.7 0.0 4.0 4 0 0 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit STAR_dimer PF16544.5 CCH62650.1 - 5 6.8 5.9 2.9 7.5 0.1 3.5 4 0 0 4 4 4 0 Homodimerisation region of STAR domain protein cwf18 PF08315.12 CCH62651.1 - 2 9.1 30.1 0.25 12.0 23.5 2.2 2 1 0 2 2 2 0 cwf18 pre-mRNA splicing factor UPF0016 PF01169.19 CCH62652.1 - 2.6e-39 133.4 22.6 1.9e-19 69.7 8.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 AAA PF00004.29 CCH62653.1 - 4.5e-31 108.0 0.0 1.2e-30 106.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH62653.1 - 1.7e-06 28.4 0.1 6.4e-06 26.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CCH62653.1 - 0.0003 21.2 0.0 0.00083 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CCH62653.1 - 0.00033 20.6 0.1 0.036 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCH62653.1 - 0.00038 20.6 0.0 0.02 15.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCH62653.1 - 0.00046 19.7 0.0 0.00096 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CCH62653.1 - 0.00065 19.6 0.4 0.0033 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCH62653.1 - 0.00084 19.7 0.0 0.01 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCH62653.1 - 0.00099 19.6 0.0 0.0039 17.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 CCH62653.1 - 0.0016 19.0 0.1 0.0058 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCH62653.1 - 0.0017 18.8 0.2 0.0092 16.4 0.1 2.5 2 1 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 CCH62653.1 - 0.002 18.2 4.0 0.0029 17.7 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.11 CCH62653.1 - 0.0064 16.4 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CCH62653.1 - 0.0098 15.2 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 CCH62653.1 - 0.01 15.6 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CCH62653.1 - 0.015 15.3 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CCH62653.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CCH62653.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCH62653.1 - 0.024 15.1 0.4 0.024 15.1 0.4 2.5 1 1 0 2 2 1 0 AAA domain RuvB_N PF05496.12 CCH62653.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CCH62653.1 - 0.04 13.8 0.3 0.04 13.8 0.3 2.5 2 1 1 3 3 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CCH62653.1 - 0.049 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 CCH62653.1 - 0.053 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase DUF815 PF05673.13 CCH62653.1 - 0.061 12.5 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 CCH62653.1 - 0.071 12.3 0.1 0.57 9.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 CCH62653.1 - 0.12 12.3 4.0 0.81 9.7 0.1 3.2 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CCH62653.1 - 0.17 11.3 0.0 0.37 10.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 CCH62653.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain BRO1 PF03097.18 CCH62654.1 - 6.3e-91 305.1 8.2 9.9e-91 304.4 8.2 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCH62654.1 - 2.6e-23 82.8 13.8 9.5e-23 80.9 13.8 1.9 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Flexi_CP_N PF08358.10 CCH62654.1 - 1 9.4 6.9 23 5.1 0.1 4.2 4 0 0 4 4 4 0 Carlavirus coat MBA1 PF07961.11 CCH62655.1 - 2.7e-76 255.7 0.7 3.2e-76 255.5 0.7 1.0 1 0 0 1 1 1 1 MBA1-like protein Sec16_C PF12931.7 CCH62656.1 - 3.4e-65 220.7 2.5 7.5e-65 219.5 2.5 1.6 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CCH62656.1 - 2.4e-05 24.9 0.3 0.00025 21.6 0.0 2.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 CCH62656.1 - 0.00043 20.5 12.8 0.00043 20.5 12.8 3.3 2 1 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus Nup96 PF12110.8 CCH62656.1 - 0.00072 18.8 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Ceramidase PF05875.12 CCH62657.1 - 3.6e-89 298.7 15.8 4.5e-89 298.4 15.8 1.0 1 0 0 1 1 1 1 Ceramidase DUF4405 PF14358.6 CCH62657.1 - 0.00048 20.6 1.4 1.7 9.3 0.0 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4405) DUF4181 PF13789.6 CCH62657.1 - 0.012 15.9 2.5 0.012 15.9 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF4079 PF13301.6 CCH62657.1 - 0.026 14.7 0.0 0.082 13.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 CCH62657.1 - 0.052 12.5 17.0 0.0092 14.9 8.0 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF3043 PF11241.8 CCH62657.1 - 0.5 10.4 1.0 0.91 9.5 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Leader_Trp PF08255.11 CCH62657.1 - 3 8.0 8.5 0.36 10.9 2.1 3.0 2 0 0 2 2 2 0 Trp-operon Leader Peptide SRF-TF PF00319.18 CCH62658.1 - 3e-20 71.4 0.1 6.1e-20 70.5 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) QSregVF_b PF12843.7 CCH62658.1 - 0.033 14.1 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Pyr_redox_2 PF07992.14 CCH62659.1 - 6.5e-58 196.3 0.8 1.1e-57 195.5 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCH62659.1 - 3.8e-34 117.3 0.0 3e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCH62659.1 - 5.2e-19 68.6 5.7 7.1e-18 65.0 1.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCH62659.1 - 4.7e-12 45.8 4.1 1.6e-11 44.0 4.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCH62659.1 - 8.2e-07 28.7 0.9 1.4e-06 27.9 0.3 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CCH62659.1 - 6.5e-06 25.5 0.3 0.00065 18.9 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 CCH62659.1 - 1.8e-05 24.0 0.0 2.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CCH62659.1 - 1.9e-05 24.0 0.3 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CCH62659.1 - 4.7e-05 22.3 5.8 0.082 11.6 0.3 3.7 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 CCH62659.1 - 0.0067 15.6 1.4 0.057 12.5 1.2 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CCH62659.1 - 0.031 13.9 10.1 0.14 11.7 0.4 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CCH62659.1 - 0.047 13.1 1.4 11 5.3 0.1 3.2 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CCH62659.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CCH62659.1 - 0.081 13.4 0.1 4.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CCH62659.1 - 0.21 10.8 1.9 3.3 6.9 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 CCH62659.1 - 6 7.2 10.0 0.052 13.8 1.8 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain SLAC1 PF03595.17 CCH62660.1 - 1.7e-72 244.4 35.2 2e-72 244.2 35.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SAYSvFN PF10260.9 CCH62660.1 - 0.28 11.2 0.1 0.28 11.2 0.1 4.8 5 0 0 5 5 5 0 Uncharacterized conserved domain (SAYSvFN) Sec62 PF03839.16 CCH62661.1 - 1.2e-61 208.0 4.6 1.3e-61 207.9 0.0 2.1 1 1 1 2 2 2 1 Translocation protein Sec62 Dynamin_N PF00350.23 CCH62662.1 - 2.8e-11 43.8 2.7 2.8e-11 43.8 2.7 4.5 5 1 0 5 5 5 1 Dynamin family MMR_HSR1 PF01926.23 CCH62662.1 - 2e-08 34.3 2.7 2e-07 31.1 1.5 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCH62662.1 - 1.4e-07 31.3 0.3 0.00014 21.5 0.1 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Hpr_kinase_C PF07475.12 CCH62662.1 - 0.14 11.7 0.9 7.3 6.1 0.0 3.3 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 CCH62662.1 - 2.3 8.8 0.0 2.3 8.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain Abhydrolase_1 PF00561.20 CCH62663.1 - 9.5e-24 84.4 0.0 1.7e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCH62663.1 - 7.5e-10 38.5 0.0 3.1e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCH62663.1 - 1.8e-05 25.5 0.0 3.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CCH62663.1 - 0.0076 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF1648 PF07853.11 CCH62663.1 - 0.044 13.4 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Rad4 PF03835.15 CCH62664.1 - 1.6e-11 44.1 0.8 4.8e-11 42.5 0.8 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CCH62664.1 - 3.6e-10 40.3 0.1 7.1e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Zn-ribbon_8 PF09723.10 CCH62664.1 - 0.0061 16.7 0.9 4.8 7.4 0.2 2.9 2 0 0 2 2 2 2 Zinc ribbon domain HisK_N PF09385.10 CCH62664.1 - 0.012 15.6 0.2 0.029 14.3 0.1 1.8 2 0 0 2 2 2 0 Histidine kinase N terminal Zn_Tnp_IS1595 PF12760.7 CCH62664.1 - 0.089 12.8 4.0 0.32 11.0 4.0 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zf-HIT PF04438.16 CCH62664.1 - 2.7 8.0 5.6 2.7 7.9 0.7 2.8 2 0 0 2 2 2 0 HIT zinc finger zf-TFIIB PF13453.6 CCH62664.1 - 3.5 7.0 8.5 4.6 6.7 6.0 2.4 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF35_N PF12172.8 CCH62664.1 - 5.7 6.9 5.9 5 7.1 0.0 2.7 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PIG-Y PF15159.6 CCH62665.1 - 0.0088 16.9 12.7 0.015 16.2 12.7 1.3 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Bax1-I PF01027.20 CCH62665.1 - 0.012 15.4 2.6 0.012 15.4 2.6 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 tRNA-synt_1b PF00579.25 CCH62666.1 - 1.8e-75 254.0 0.2 2.3e-75 253.6 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 CCH62666.1 - 0.037 13.7 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 S4 domain Polysacc_syn_2C PF08485.10 CCH62666.1 - 0.083 12.6 0.1 0.19 11.4 0.1 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal NAD_synthase PF02540.17 CCH62666.1 - 0.1 11.7 0.1 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 NAD synthase Romo1 PF10247.9 CCH62667.1 - 1.6e-26 92.4 10.0 2.1e-26 92.1 10.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 ANAPC4_WD40 PF12894.7 CCH62668.1 - 4.2e-05 23.7 0.0 6.9 7.0 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH62668.1 - 0.023 15.6 0.9 7.8 7.6 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat NPL4 PF05021.15 CCH62669.1 - 2.2e-130 434.5 0.1 3.3e-130 433.9 0.1 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CCH62669.1 - 3.6e-67 225.0 1.5 7.3e-67 224.0 1.5 1.5 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CCH62669.1 - 5.5e-07 30.0 0.0 1.8e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF1906 PF08924.11 CCH62669.1 - 0.0022 18.2 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1906) HSP70 PF00012.20 CCH62670.1 - 1.1e-151 506.0 1.3 1.6e-151 505.5 1.3 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH62670.1 - 4.1e-09 35.7 0.3 1.1e-08 34.3 0.1 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CCH62670.1 - 0.02 15.3 2.2 0.063 13.7 0.6 2.5 2 1 0 2 2 2 0 Cell division protein FtsA Oxidored-like PF09791.9 CCH62671.1 - 2.4e-22 78.3 2.7 3.7e-22 77.7 2.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PRANC PF09372.10 CCH62671.1 - 0.073 13.4 1.4 12 6.3 0.2 2.4 2 0 0 2 2 2 0 PRANC domain Sec31 PF11549.8 CCH62671.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein transport protein SEC31 Zn_clus PF00172.18 CCH62672.1 - 2.1e-09 37.3 12.3 2.1e-09 37.3 12.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3589 PF12141.8 CCH62673.1 - 2.2e-78 264.0 9.4 4.3e-50 170.7 0.3 2.5 1 1 1 2 2 2 2 Beta-mannosyltransferases Flocculin PF00624.18 CCH62675.1 - 1.4e-100 329.3 499.6 6.7e-14 51.9 21.5 24.1 24 0 0 24 24 24 15 Flocculin repeat GFO_IDH_MocA PF01408.22 CCH62676.1 - 1.8e-18 67.5 0.0 3.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCH62676.1 - 1.9e-09 37.6 0.0 3.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DCP1 PF06058.13 CCH62677.1 - 1.4e-25 89.5 0.1 4e-23 81.6 0.1 2.4 1 1 0 1 1 1 1 Dcp1-like decapping family Kelch_1 PF01344.25 CCH62677.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Kelch motif Spt20 PF12090.8 CCH62678.1 - 1.7e-56 191.5 57.0 3.6e-40 138.1 26.4 6.1 3 2 1 4 4 4 2 Spt20 family PEX11 PF05648.14 CCH62679.1 - 1.2e-59 201.5 4.6 1.4e-59 201.3 4.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sld5 PF05916.11 CCH62680.1 - 2.2e-13 50.6 0.0 2.8e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein TPR_2 PF07719.17 CCH62681.1 - 1.3e-25 87.4 29.1 0.001 19.0 0.1 13.8 15 1 0 15 15 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 CCH62681.1 - 1.7e-21 75.1 42.4 2.9e-05 23.7 0.1 14.2 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62681.1 - 1.4e-19 68.6 37.7 0.0047 17.0 0.0 14.5 16 1 0 16 16 16 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCH62681.1 - 2.2e-18 66.3 16.3 0.001 19.3 0.0 10.7 7 4 4 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCH62681.1 - 2.2e-13 50.5 2.5 0.013 16.0 0.0 8.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCH62681.1 - 4.7e-12 45.7 9.8 0.35 11.6 0.0 11.6 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH62681.1 - 2.1e-11 43.7 0.1 8.4 7.5 0.0 10.4 8 3 4 12 12 12 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCH62681.1 - 3.9e-10 40.2 0.0 0.074 13.7 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCH62681.1 - 3.9e-08 33.1 9.5 9.2 6.9 0.0 9.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH62681.1 - 9.7e-06 25.3 14.7 0.057 13.5 0.0 8.8 11 0 0 11 11 10 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH62681.1 - 1.2e-05 25.4 17.5 0.8 10.0 0.0 8.6 8 2 3 11 11 11 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCH62681.1 - 0.00011 22.0 15.1 1.2 9.1 0.0 8.4 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62681.1 - 0.0066 16.1 22.0 3.6 7.3 0.0 9.4 11 2 2 13 13 13 2 TPR repeat PPR PF01535.20 CCH62681.1 - 0.068 13.5 1.2 38 4.9 0.0 5.2 6 0 0 6 6 5 0 PPR repeat Fis1_TPR_C PF14853.6 CCH62681.1 - 0.74 9.9 17.8 21 5.3 0.0 7.4 9 0 0 9 9 9 0 Fis1 C-terminal tetratricopeptide repeat LAMTOR PF15454.6 CCH62682.1 - 2.7e-17 63.2 3.7 3.3e-17 62.9 3.7 1.1 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Ribosomal_L50 PF10501.9 CCH62683.1 - 1.2e-27 96.3 1.8 2.4e-27 95.3 1.8 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF809 PF05663.11 CCH62683.1 - 0.023 14.8 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Nas2_N PF18265.1 CCH62683.1 - 0.024 14.6 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Nas2 N_terminal domain Snf7 PF03357.21 CCH62684.1 - 2.6e-33 115.0 21.5 3.9e-31 107.9 21.8 2.0 1 1 1 2 2 2 2 Snf7 Ist1 PF03398.14 CCH62684.1 - 1.1e-05 25.4 7.0 1.5e-05 25.0 7.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Uds1 PF15456.6 CCH62684.1 - 0.061 13.5 4.0 0.24 11.6 0.1 2.3 2 0 0 2 2 2 0 Up-regulated During Septation PAXX PF15384.6 CCH62684.1 - 0.1 12.3 1.0 0.14 11.8 1.0 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Hpt PF01627.23 CCH62684.1 - 0.53 10.6 3.7 0.25 11.6 0.5 2.1 2 1 0 2 2 2 0 Hpt domain Ribosomal_S6 PF01250.17 CCH62685.1 - 2.7e-24 85.3 0.0 3.4e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 NAD_binding_10 PF13460.6 CCH62686.1 - 1.8e-40 138.8 0.0 2.1e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CCH62686.1 - 1.3e-06 27.7 0.2 1.7e-06 27.2 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCH62686.1 - 2.4e-06 28.0 0.0 4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CCH62686.1 - 0.00011 22.3 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 CCH62686.1 - 0.003 18.1 0.0 0.0064 17.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 CCH62686.1 - 0.0091 15.5 0.1 0.024 14.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 CCH62686.1 - 0.019 15.1 0.1 0.032 14.3 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CCH62686.1 - 0.065 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 CCH62686.1 - 0.091 13.6 0.0 0.17 12.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DHOase PF12890.7 CCH62686.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydro-orotase-like Thymidylate_kin PF02223.17 CCH62687.1 - 4.1e-38 130.9 0.0 5.5e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 CCH62687.1 - 0.023 14.8 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L14e PF01929.17 CCH62688.1 - 1.6e-31 108.6 2.8 2.5e-31 108.0 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CCH62688.1 - 0.0012 18.7 0.1 0.003 17.5 0.1 1.7 1 0 0 1 1 1 1 KOW motif TRAM_LAG1_CLN8 PF03798.16 CCH62689.1 - 3.9e-41 141.0 24.5 3.9e-41 141.0 24.5 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CCH62689.1 - 2.3e-22 78.4 1.7 5.3e-22 77.2 1.7 1.7 1 0 0 1 1 1 1 TRAM1-like protein FAM176 PF14851.6 CCH62689.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 CCH62689.1 - 0.034 12.2 7.2 0.05 11.7 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 CCH62689.1 - 0.073 13.5 10.3 0.17 12.3 10.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CCH62689.1 - 0.24 10.7 9.2 0.36 10.1 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 CCH62689.1 - 1.9 8.5 5.3 1.6 8.8 3.5 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 CCH62689.1 - 3.2 5.8 10.6 5 5.1 10.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CCH62689.1 - 5.3 5.2 5.8 7.3 4.8 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CCH62689.1 - 6.5 4.8 8.8 9.3 4.3 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S2 PF00318.20 CCH62690.1 - 6.1e-54 182.5 9.2 3.9e-53 179.9 5.9 3.0 2 1 0 2 2 2 1 Ribosomal protein S2 Methyltransf_18 PF12847.7 CCH62690.1 - 0.078 12.9 2.7 0.19 11.7 0.3 2.2 2 0 0 2 2 2 0 Methyltransferase domain HECT PF00632.25 CCH62692.1 - 1.1e-67 228.7 9.6 1.9e-67 227.9 1.4 2.7 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 CCH62693.1 - 5e-73 245.7 0.0 9.6e-73 244.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62693.1 - 4.3e-48 163.9 0.0 8.7e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCH62693.1 - 8.7e-23 80.5 0.0 4e-22 78.3 0.0 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CCH62693.1 - 1.9e-05 24.1 0.0 4.5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CCH62693.1 - 0.21 11.5 0.0 1.9 8.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family CUE PF02845.16 CCH62694.1 - 5.3e-05 22.8 1.0 0.0021 17.7 0.4 2.6 2 0 0 2 2 2 1 CUE domain Smr PF01713.21 CCH62694.1 - 0.00082 19.7 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 Smr domain TAP_C PF03943.13 CCH62694.1 - 0.0079 15.8 0.1 0.13 11.9 0.0 2.7 3 0 0 3 3 3 1 TAP C-terminal domain DMA PF03474.14 CCH62694.1 - 0.12 12.0 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif bZIP_1 PF00170.21 CCH62695.1 - 0.00046 20.2 22.3 0.00076 19.5 20.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 CCH62695.1 - 0.031 14.1 3.1 0.062 13.1 3.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Exo84_C PF16528.5 CCH62695.1 - 0.25 11.2 4.5 0.48 10.2 4.5 1.4 1 0 0 1 1 1 0 Exocyst component 84 C-terminal bZIP_Maf PF03131.17 CCH62695.1 - 0.31 11.6 11.1 0.72 10.4 11.1 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.19 CCH62695.1 - 0.43 8.4 4.8 0.55 8.1 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 CCH62695.1 - 0.61 10.2 24.7 0.17 11.9 21.1 1.9 1 1 1 2 2 2 0 Basic region leucine zipper Myosin-VI_CBD PF16521.5 CCH62696.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Myosin VI cargo binding domain EMP70 PF02990.16 CCH62697.1 - 7.2e-107 358.2 29.8 1.4e-106 357.2 29.8 1.5 1 0 0 1 1 1 1 Endomembrane protein 70 LSM PF01423.22 CCH62698.1 - 4.5e-15 55.1 0.6 7.6e-15 54.4 0.6 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCH62698.1 - 7.2e-05 22.8 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Hydin_ADK PF17213.3 CCH62698.1 - 0.98 9.7 7.9 1.4 9.2 7.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain WD40 PF00400.32 CCH62699.1 - 1.8e-17 63.4 10.6 4.6e-05 24.1 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62699.1 - 3.7e-09 36.8 0.2 0.11 12.8 0.0 4.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCH62699.1 - 0.0025 16.5 0.5 0.98 8.0 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCH62699.1 - 0.0082 15.1 0.4 0.041 12.8 0.0 2.4 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCH62699.1 - 0.039 13.3 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain MAM1 PF10434.9 CCH62700.1 - 5.2e-37 127.9 19.7 5.2e-37 127.9 19.7 2.2 1 1 1 2 2 2 1 Monopolin complex protein MAM1 Tox-PL-2 PF15643.6 CCH62700.1 - 0.54 10.4 5.1 0.19 11.8 1.5 2.2 2 0 0 2 2 2 0 Papain fold toxin 2 Atg8 PF02991.16 CCH62701.1 - 1.4e-49 166.6 0.1 1.6e-49 166.4 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CCH62701.1 - 2.2e-06 28.0 0.0 2.8e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.22 CCH62703.1 - 3e-237 788.7 1.2 3e-237 788.7 1.2 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCH62703.1 - 5.2e-27 94.7 0.1 1.7e-26 93.0 0.0 2.0 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCH62703.1 - 5.5e-17 61.6 2.1 4.2e-05 22.5 0.2 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CCH62703.1 - 7e-05 22.3 0.0 0.00056 19.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Ribosomal_S8e PF01201.22 CCH62704.1 - 6.5e-56 188.3 1.5 7.5e-56 188.1 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.13 CCH62705.1 - 3.1e-17 62.0 0.5 4.1e-17 61.7 0.5 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CCH62705.1 - 0.004 17.3 0.8 0.0065 16.6 0.8 1.3 1 0 0 1 1 1 1 Zinc ribbon domain DUF5348 PF17295.2 CCH62705.1 - 0.034 14.0 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Nudix_N_2 PF14803.6 CCH62705.1 - 0.062 13.2 0.4 0.11 12.5 0.4 1.4 1 1 0 1 1 1 0 Nudix N-terminal ADH_zinc_N_2 PF13602.6 CCH62706.1 - 8.9e-12 46.2 0.0 1.9e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH62706.1 - 0.00033 20.5 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rad51 PF08423.11 CCH62707.1 - 3.8e-128 426.1 0.0 6.3e-128 425.4 0.0 1.4 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CCH62707.1 - 1.7e-12 47.4 0.0 2.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CCH62707.1 - 3.7e-10 39.7 0.1 5.9e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CCH62707.1 - 8.6e-08 32.7 0.2 1.8e-07 31.6 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CCH62707.1 - 4.1e-07 29.6 1.9 1.1e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 KaiC Sec7 PF01369.20 CCH62708.1 - 2.3e-12 46.9 0.8 8.1e-12 45.2 0.8 1.9 1 0 0 1 1 1 1 Sec7 domain Proteasome PF00227.26 CCH62709.1 - 2.5e-42 144.5 0.0 3e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.10 CCH62710.1 - 6.1e-11 42.2 5.7 1e-10 41.4 5.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CCH62710.1 - 0.025 14.3 4.2 0.048 13.4 4.2 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 CCH62710.1 - 0.15 12.2 2.5 3.1 8.1 2.8 2.2 1 1 1 2 2 2 0 CHCH domain Meth_synt_2 PF01717.18 CCH62711.1 - 1e-148 494.9 0.0 1.6e-144 481.1 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CCH62711.1 - 3.4e-119 398.0 0.0 1.2e-111 373.3 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain VbhA PF18495.1 CCH62711.1 - 0.057 13.3 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Antitoxin VbhA Na_Ca_ex PF01699.24 CCH62712.1 - 5.9e-21 75.0 36.3 1.6e-15 57.4 12.8 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 CCH62712.1 - 2e-12 47.6 5.9 2e-12 47.6 5.9 3.8 4 0 0 4 4 4 1 Inner membrane component domain PrmA PF06325.13 CCH62712.1 - 0.4 10.0 4.4 0.69 9.2 4.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) KRE1 PF17056.5 CCH62713.1 - 2.8e-17 62.2 5.3 2.8e-17 62.2 5.3 7.4 3 1 4 7 7 7 1 Killer toxin-resistance protein 1 baeRF_family11 PF18855.1 CCH62713.1 - 0.25 11.7 5.8 5.1 7.4 0.4 2.9 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 11 DUF824 PF05688.11 CCH62713.1 - 1.7 8.6 15.3 0.66 9.9 0.2 4.9 4 0 0 4 4 4 0 Salmonella repeat of unknown function (DUF824) CDC50 PF03381.15 CCH62714.1 - 3.6e-83 279.3 2.4 5e-83 278.9 2.4 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA PF00004.29 CCH62715.1 - 2.7e-52 176.7 0.0 1.6e-44 151.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH62715.1 - 8.8e-09 35.0 0.0 9.3e-06 25.4 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CCH62715.1 - 0.00026 21.4 0.0 0.044 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.17 CCH62715.1 - 0.00029 20.0 0.0 0.00074 18.7 0.0 1.6 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RuvB_N PF05496.12 CCH62715.1 - 0.00088 19.1 0.0 0.0039 16.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCH62715.1 - 0.0018 18.4 0.0 0.028 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 CCH62715.1 - 0.0038 16.8 0.1 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 CCH62715.1 - 0.0078 16.2 0.0 0.058 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCH62715.1 - 0.0095 16.3 0.0 0.041 14.3 0.0 2.2 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.13 CCH62715.1 - 0.011 14.9 0.0 0.033 13.4 0.0 1.8 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 CCH62715.1 - 0.014 15.6 0.0 0.11 12.7 0.0 2.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CCH62715.1 - 0.018 14.4 0.1 0.04 13.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 CCH62715.1 - 0.021 14.8 0.0 0.09 12.8 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 CCH62715.1 - 0.025 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CCH62715.1 - 0.088 12.8 0.1 0.53 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCH62715.1 - 0.13 12.8 0.0 0.5 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Hist_deacetyl PF00850.19 CCH62716.1 - 1.2e-83 281.2 0.1 1.9e-83 280.5 0.0 1.3 2 0 0 2 2 2 1 Histone deacetylase domain DMRL_synthase PF00885.19 CCH62717.1 - 5.1e-52 175.5 0.1 6e-52 175.2 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2390 PF09523.10 CCH62717.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) RRM_1 PF00076.22 CCH62718.1 - 0.039 13.8 0.5 0.1 12.4 0.5 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.25 CCH62719.1 - 2.2e-29 101.3 9.7 2.5e-20 72.3 0.5 2.9 3 0 0 3 3 3 2 Bromodomain adh_short PF00106.25 CCH62720.1 - 3.9e-86 287.5 7.9 2.8e-44 150.9 0.4 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCH62720.1 - 7.5e-69 231.8 0.2 2e-36 125.7 0.0 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CCH62720.1 - 8.3e-31 106.1 0.0 1.9e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CCH62720.1 - 9.2e-31 107.1 1.0 2.2e-14 53.8 0.1 2.3 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 CCH62720.1 - 0.27 11.1 2.1 18 5.2 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Adap_comp_sub PF00928.21 CCH62721.1 - 3e-33 115.3 3.9 3.9e-25 88.7 0.1 2.5 2 1 0 2 2 2 2 Adaptor complexes medium subunit family Myc_N PF01056.18 CCH62721.1 - 0.023 14.6 4.3 0.025 14.5 2.1 1.9 2 0 0 2 2 2 0 Myc amino-terminal region LAT PF15234.6 CCH62721.1 - 1.1 8.9 4.0 2.4 7.8 4.0 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells Prothymosin PF03247.14 CCH62721.1 - 5.2 7.6 22.1 0.16 12.4 11.8 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Ribosomal_60s PF00428.19 CCH62721.1 - 5.4 7.7 10.5 12 6.6 10.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein SNF5 PF04855.12 CCH62722.1 - 1.1e-48 166.2 1.4 1.1e-48 166.2 1.4 6.0 3 3 1 4 4 4 1 SNF5 / SMARCB1 / INI1 Mito_carr PF00153.27 CCH62723.1 - 6.3e-58 192.7 3.6 1.6e-20 72.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_morph_reg PF14972.6 CCH62723.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator MgtC PF02308.16 CCH62723.1 - 0.19 12.1 1.6 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 MgtC family Aldedh PF00171.22 CCH62724.1 - 1.9e-74 250.8 0.0 2.4e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family She2p PF11435.8 CCH62725.1 - 1e-78 263.6 13.8 1.6e-78 263.0 13.8 1.3 1 0 0 1 1 1 1 RNA binding protein She2p GCR1_C PF12550.8 CCH62726.1 - 2.7e-23 82.1 0.0 1.1e-22 80.1 0.0 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes TylF PF05711.11 CCH62726.1 - 0.13 11.5 0.2 1.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Macrocin-O-methyltransferase (TylF) Peroxin-13_N PF04088.13 CCH62726.1 - 0.89 9.8 8.5 1.2 9.4 2.9 2.6 2 1 0 2 2 2 0 Peroxin 13, N-terminal region Fucokinase PF07959.12 CCH62726.1 - 3.6 6.4 12.0 0.12 11.3 6.1 1.4 2 0 0 2 2 2 0 L-fucokinase Mur_ligase_M PF08245.12 CCH62727.1 - 1.6e-07 31.5 0.5 4.1e-07 30.2 0.3 1.9 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CCH62727.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPR_12 PF13424.6 CCH62728.1 - 1.9e-05 24.9 6.0 0.0032 17.7 0.5 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCH62728.1 - 4.7e-05 23.1 2.3 0.53 10.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62728.1 - 9.9e-05 22.2 5.0 0.58 10.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat KBP_C PF12309.8 CCH62728.1 - 0.0015 18.1 1.0 1.1 8.7 0.1 2.5 2 0 0 2 2 2 2 KIF-1 binding protein C terminal TPR_1 PF00515.28 CCH62728.1 - 0.0021 17.8 5.1 3.6 7.6 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCH62728.1 - 0.0023 18.4 3.0 0.29 11.7 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH62728.1 - 0.0023 18.6 1.8 6.8 7.8 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62728.1 - 0.0035 17.4 9.1 0.96 9.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCH62728.1 - 0.012 15.6 0.1 1.5 9.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCH62728.1 - 0.037 14.7 2.6 0.14 12.9 1.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M3 PF01432.20 CCH62729.1 - 2e-130 436.2 0.0 2.4e-130 435.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CCH62729.1 - 0.28 10.8 0.4 0.44 10.2 0.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like SAC3_GANP PF03399.16 CCH62730.1 - 1.9e-11 43.9 14.3 1.2e-09 38.0 14.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 CCH62730.1 - 0.03 14.8 9.7 0.84 10.2 7.8 3.4 2 1 0 2 2 2 0 PCI domain SF3A3 PF16837.5 CCH62730.1 - 0.24 12.0 7.8 0.33 11.5 0.9 2.7 2 2 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 QueH PF02677.14 CCH62730.1 - 2.1 8.4 6.3 0.25 11.4 1.6 1.9 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH PX PF00787.24 CCH62731.1 - 9e-06 25.6 0.4 0.00014 21.8 0.0 2.6 2 0 0 2 2 2 1 PX domain Mito_carr PF00153.27 CCH62732.1 - 1e-69 230.5 9.5 1.9e-24 85.4 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ysc84 PF04366.12 CCH62732.1 - 0.00078 19.2 1.8 0.0014 18.4 1.8 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Fip1 PF05182.13 CCH62734.1 - 7.3e-20 70.2 0.7 1.3e-19 69.4 0.7 1.4 1 0 0 1 1 1 1 Fip1 motif eIF-5_eIF-2B PF01873.17 CCH62735.1 - 5.4e-37 126.2 0.0 1e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CCH62735.1 - 3.3e-22 78.4 0.0 3.3e-22 78.4 0.0 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon TPR_2 PF07719.17 CCH62736.1 - 3e-05 23.8 2.4 0.00033 20.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCH62736.1 - 0.013 15.3 0.7 0.17 11.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62736.1 - 0.081 12.6 0.1 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 TPR repeat dsrm PF00035.26 CCH62737.1 - 0.0003 21.4 0.4 0.0057 17.3 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF3666 PF12408.8 CCH62737.1 - 0.092 12.0 0.3 0.5 9.6 0.0 2.4 3 0 0 3 3 3 0 Ribose-5-phosphate isomerase SIS PF01380.22 CCH62738.1 - 1.9e-62 208.9 0.0 2.3e-31 108.4 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CCH62738.1 - 1.5e-14 54.3 0.0 2.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCH62738.1 - 2.7e-09 37.0 0.0 5.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CCH62738.1 - 4.6e-06 25.7 0.0 7.7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Evr1_Alr PF04777.13 CCH62739.1 - 4.4e-23 81.6 0.1 6.5e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 CCH62739.1 - 0.038 14.2 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 APOBEC1 SNAD4 PF18750.1 CCH62739.1 - 0.046 13.9 0.1 0.069 13.3 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 CCH62739.1 - 0.076 13.1 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 CCH62739.1 - 0.089 12.7 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase G-gamma PF00631.22 CCH62740.1 - 2.3e-18 65.9 0.1 3.2e-18 65.5 0.1 1.2 1 0 0 1 1 1 1 GGL domain PCI PF01399.27 CCH62742.1 - 3.2e-10 40.4 0.2 4.3e-09 36.8 0.0 2.6 3 0 0 3 3 3 1 PCI domain V-ATPase_H_N PF03224.14 CCH62743.1 - 1.3e-50 172.5 12.6 1.3e-50 172.5 12.6 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CCH62743.1 - 5.1e-39 133.0 0.2 5.1e-39 133.0 0.2 3.8 2 1 1 4 4 4 1 V-ATPase subunit H RICTOR_M PF14666.6 CCH62743.1 - 0.093 12.5 3.5 0.29 10.9 0.1 3.3 2 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain Gln-synt_C PF00120.24 CCH62744.1 - 8.9e-22 77.5 0.0 6.5e-17 61.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CCH62744.1 - 5e-13 48.6 0.0 9.2e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain NuA4 PF09340.10 CCH62745.1 - 4.4e-24 84.2 1.1 4.4e-24 84.2 1.1 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Tmemb_cc2 PF10267.9 CCH62745.1 - 0.016 14.4 6.4 0.022 13.9 6.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4407 PF14362.6 CCH62745.1 - 1.7 7.9 7.1 2.2 7.6 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIM24 PF01987.17 CCH62746.1 - 6.5e-22 78.3 0.0 9.8e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 tRNA-synt_His PF13393.6 CCH62747.1 - 4.4e-36 124.7 0.0 3e-31 108.9 0.0 2.0 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CCH62747.1 - 6.8e-15 55.0 0.0 1.4e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCH62747.1 - 0.0011 19.0 0.2 0.0055 16.7 0.4 2.2 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 CCH62747.1 - 0.033 13.7 0.5 0.088 12.3 0.0 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 CCH62747.1 - 0.13 11.8 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) OGG_N PF07934.12 CCH62747.1 - 0.16 12.1 0.4 0.39 10.8 0.0 1.9 2 1 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Cid2 PF09774.9 CCH62748.1 - 3.5e-39 134.8 10.2 4.9e-39 134.3 10.2 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Lgl_C PF08596.10 CCH62749.1 - 5.7e-109 364.4 0.3 9.7e-109 363.6 0.3 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CCH62749.1 - 2.3e-11 43.8 0.5 0.045 14.0 0.0 6.1 5 1 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCH62749.1 - 5.2e-06 27.1 0.6 0.077 13.9 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 CCH62749.1 - 0.00018 20.9 0.1 0.00045 19.6 0.1 1.6 1 0 0 1 1 1 1 WD40-like domain Pkinase PF00069.25 CCH62750.1 - 1.8e-59 201.2 0.1 6.1e-59 199.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62750.1 - 4.1e-34 118.0 0.0 7.9e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CCH62750.1 - 1.4e-21 76.3 29.3 2.3e-13 50.0 7.2 2.9 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 CCH62750.1 - 4.7e-20 71.2 32.1 4.1e-12 45.8 11.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CCH62750.1 - 1.1e-10 42.0 0.8 7.4e-10 39.4 0.8 2.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CCH62750.1 - 5.2e-06 26.7 0.1 1.5e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CCH62750.1 - 0.0011 18.3 3.1 0.0025 17.2 0.1 2.7 2 1 1 3 3 3 1 Kinase-like C1_2 PF03107.16 CCH62750.1 - 5.4 7.4 26.5 5 7.5 7.7 2.5 2 0 0 2 2 2 0 C1 domain zinc_ribbon_16 PF17034.5 CCH62751.1 - 4.2e-25 88.4 18.9 7.6e-24 84.3 17.0 3.0 2 1 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CCH62751.1 - 0.00024 20.6 6.7 0.00024 20.6 6.7 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Malectin PF11721.8 CCH62751.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Malectin domain HLH PF00010.26 CCH62752.1 - 8e-12 44.9 2.0 1.9e-11 43.7 2.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 CCH62753.1 - 4.8e-32 110.7 14.6 8.2e-32 110.0 14.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.16 CCH62753.1 - 0.0007 18.6 9.1 0.00082 18.4 9.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4085 PF13315.6 CCH62753.1 - 0.049 13.3 0.1 0.072 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) WXG100 PF06013.12 CCH62753.1 - 0.3 11.3 2.3 0.42 10.9 2.3 1.1 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF2157 PF09925.9 CCH62753.1 - 0.5 10.1 6.9 0.45 10.3 5.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 CCH62753.1 - 1.3 7.7 5.7 6.4 5.4 5.7 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Arrestin_C PF02752.22 CCH62754.1 - 1e-14 55.2 0.0 7.4e-13 49.1 0.0 3.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCH62754.1 - 0.0053 16.8 0.2 0.047 13.8 0.1 2.5 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RepB-RCR_reg PF10723.9 CCH62754.1 - 0.016 15.2 0.2 0.042 13.8 0.2 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB Adaptin_N PF01602.20 CCH62755.1 - 1.3e-104 350.7 15.2 1.5e-104 350.4 15.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CCH62755.1 - 1.7e-08 34.7 2.7 3.8e-08 33.6 0.8 2.4 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 CCH62755.1 - 0.046 13.8 3.5 5.7 7.0 0.0 3.6 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 LPP20 PF02169.16 CCH62755.1 - 0.37 11.2 5.8 13 6.3 0.0 3.5 4 0 0 4 4 4 0 LPP20 lipoprotein TB2_DP1_HVA22 PF03134.19 CCH62756.1 - 5.7e-26 90.3 5.7 5.7e-26 90.3 5.7 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Glyco_hydro_65m PF03632.15 CCH62757.1 - 1.5e-32 113.0 1.4 1.7e-29 102.9 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CCH62757.1 - 3.3e-19 69.4 0.7 6.9e-19 68.4 0.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CCH62757.1 - 3.7e-06 26.7 0.1 9.6e-05 22.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain ATP-synt_ab PF00006.25 CCH62758.1 - 3.6e-71 239.2 0.0 5.6e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CCH62758.1 - 7.2e-48 162.1 0.2 1.3e-47 161.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CCH62758.1 - 1.6e-17 63.8 0.9 4e-17 62.5 0.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ArfGap PF01412.18 CCH62759.1 - 6.9e-34 116.4 0.9 6.9e-34 116.4 0.9 2.4 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Rox3 PF08633.10 CCH62760.1 - 2.3e-34 119.5 3.2 2.7e-34 119.2 3.2 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.18 CCH62761.1 - 9.3e-47 157.9 3.3 1.1e-46 157.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Motile_Sperm PF00635.26 CCH62762.1 - 1.3e-27 95.8 0.0 2.5e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CCH62762.1 - 0.0056 16.9 0.1 0.0099 16.1 0.1 1.4 1 0 0 1 1 1 1 Transmembrane protein 131-like PapD-like PF14874.6 CCH62762.1 - 0.019 15.1 0.1 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 Flagellar-associated PapD-like DUF5001 PF16392.5 CCH62762.1 - 0.072 13.0 0.1 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Ig-like domain Zip PF02535.22 CCH62762.1 - 0.13 11.4 2.5 0.18 11.0 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_M24 PF00557.24 CCH62763.1 - 9.6e-48 162.6 0.0 1.3e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 LIN37 PF15306.6 CCH62763.1 - 0.77 10.0 6.0 1.5 9.0 6.0 1.5 1 0 0 1 1 1 0 LIN37 DUF4710 PF15828.5 CCH62763.1 - 7.5 6.8 10.9 0.51 10.5 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) SH3_1 PF00018.28 CCH62764.1 - 6.2e-11 41.7 0.1 1.2e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH62764.1 - 1.9e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCH62764.1 - 1.3e-07 31.2 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain NT-C2 PF10358.9 CCH62766.1 - 5e-40 136.6 12.9 5.5e-38 130.0 12.9 2.6 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins RPN6_C_helix PF18503.1 CCH62766.1 - 0.042 13.6 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain PH PF00169.29 CCH62767.1 - 2.9e-19 69.5 0.0 2.3e-18 66.6 0.0 2.7 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 CCH62767.1 - 1.4e-13 50.2 0.3 2.9e-13 49.2 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH62767.1 - 9.1e-10 38.3 0.2 1.8e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 CCH62767.1 - 1.6e-08 34.5 0.1 3.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 CCH62767.1 - 0.00014 22.1 0.0 0.003 17.8 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.30 CCH62767.1 - 0.0048 17.3 0.1 0.009 16.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 CCH62767.1 - 0.007 16.0 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain MIP PF00230.20 CCH62768.1 - 3.4e-46 157.8 12.3 4.3e-46 157.5 12.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Snf7 PF03357.21 CCH62769.1 - 2.4e-31 108.6 12.3 2.7e-31 108.5 12.3 1.0 1 0 0 1 1 1 1 Snf7 HHH_2 PF12826.7 CCH62769.1 - 0.033 14.3 0.6 0.062 13.4 0.1 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Mating_N PF12731.7 CCH62769.1 - 0.045 13.8 0.3 2.6 8.2 0.0 2.4 1 1 1 2 2 2 0 Mating-type protein beta 1 S_100 PF01023.19 CCH62769.1 - 0.054 13.2 0.3 0.53 10.0 0.1 2.6 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain UvsY PF11056.8 CCH62769.1 - 0.12 12.7 9.0 0.48 10.8 5.0 2.2 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY SMC_hinge PF06470.13 CCH62769.1 - 0.17 12.2 1.2 1.7 9.0 0.2 2.1 1 1 1 2 2 2 0 SMC proteins Flexible Hinge Domain BORCS7 PF16088.5 CCH62769.1 - 0.62 10.4 11.7 1.4 9.2 0.6 2.9 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Mit_KHE1 PF10173.9 CCH62769.1 - 0.74 9.9 6.7 2.3 8.2 6.7 1.8 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF948 PF06103.11 CCH62769.1 - 2.2 8.6 6.8 1.3 9.4 1.6 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.10 CCH62769.1 - 6 7.1 9.0 4.8 7.5 0.2 2.8 1 1 2 3 3 3 0 Cortexillin I, coiled coil AAA PF00004.29 CCH62770.1 - 4.9e-11 43.2 0.1 1.9e-10 41.3 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CCH62770.1 - 5.6e-07 29.7 0.3 5.6e-07 29.7 0.3 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CCH62770.1 - 5.8e-06 26.4 0.6 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CCH62770.1 - 8e-06 25.9 0.0 3.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCH62770.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CCH62770.1 - 2.6e-05 24.5 0.0 7.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CCH62770.1 - 6.5e-05 23.2 0.0 0.00024 21.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH62770.1 - 0.00012 22.5 0.0 0.00041 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCH62770.1 - 0.0036 17.5 1.2 0.008 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CCH62770.1 - 0.0081 16.5 0.0 0.034 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA C-terminal domain Band_3_cyto PF07565.13 CCH62770.1 - 0.022 14.6 4.3 0.043 13.6 4.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AAA_11 PF13086.6 CCH62770.1 - 0.028 14.2 7.5 0.041 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CCH62770.1 - 0.035 14.2 0.5 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase TIP49 PF06068.13 CCH62770.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IPT PF01745.16 CCH62770.1 - 0.089 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase FSA_C PF10479.9 CCH62770.1 - 0.24 9.5 15.2 0.36 8.9 15.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Hydin_ADK PF17213.3 CCH62770.1 - 0.26 11.6 13.9 0.26 11.5 0.1 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain MBR1 PF17058.5 CCH62771.1 - 7e-17 62.4 17.1 7.1e-11 42.8 4.6 3.2 2 1 1 3 3 3 2 Mitochondrial biogenesis regulation protein 1 IMUP PF15761.5 CCH62771.1 - 2.9 8.6 10.8 1.1 10.0 6.1 2.2 2 0 0 2 2 2 0 Immortalisation up-regulated protein PIR PF00399.19 CCH62772.1 - 1.7e-06 27.4 5.1 1.7e-06 27.4 5.1 2.2 2 0 0 2 2 2 1 Yeast PIR protein repeat Utp11 PF03998.13 CCH62773.1 - 1.8e-58 198.4 22.5 2e-58 198.2 22.5 1.0 1 0 0 1 1 1 1 Utp11 protein ADH_N PF08240.12 CCH62774.1 - 6e-29 100.1 0.5 1.3e-28 99.1 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCH62774.1 - 3e-24 85.5 0.2 5e-24 84.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCH62774.1 - 0.0013 19.8 0.0 0.0023 19.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CCH62774.1 - 0.057 12.7 0.3 0.12 11.7 0.2 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.25 CCH62775.1 - 2.7e-69 233.5 5.1 2.3e-64 217.3 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62775.1 - 1.8e-34 119.2 0.0 2.9e-32 112.0 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CCH62775.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CCH62775.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 CCH62775.1 - 0.019 14.6 0.8 6.3 6.3 0.0 3.3 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 CCH62775.1 - 0.019 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M18 PF02127.15 CCH62776.1 - 1.2e-137 459.2 0.0 1.5e-137 459.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Aminotran_1_2 PF00155.21 CCH62778.1 - 4.8e-75 253.0 0.0 5.5e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M41 PF01434.18 CCH62779.1 - 4e-65 219.2 0.6 5.6e-64 215.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CCH62779.1 - 4.2e-42 143.7 0.0 1.1e-41 142.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH62779.1 - 2.2e-12 46.6 0.0 8.1e-12 44.8 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CCH62779.1 - 1.3e-09 38.4 3.6 1.3e-09 38.4 3.6 2.9 1 1 1 2 2 1 1 FtsH Extracellular TIP49 PF06068.13 CCH62779.1 - 0.00013 21.3 0.3 0.0085 15.3 0.0 2.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_17 PF13207.6 CCH62779.1 - 0.00032 21.1 0.6 0.0012 19.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CCH62779.1 - 0.0015 18.7 1.7 0.0067 16.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCH62779.1 - 0.0022 18.4 0.1 0.0096 16.3 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CCH62779.1 - 0.0022 17.7 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCH62779.1 - 0.004 17.4 0.1 0.7 10.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CCH62779.1 - 0.0051 16.8 0.8 0.022 14.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2281 PF10047.9 CCH62779.1 - 0.037 14.7 2.1 8.8 7.1 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2281) IstB_IS21 PF01695.17 CCH62779.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 CCH62779.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCH62779.1 - 0.16 12.6 5.4 0.81 10.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CCH62779.1 - 3.6 6.9 7.0 2.2 7.5 0.0 2.8 3 0 0 3 3 3 0 KaiC CRC_subunit PF08624.10 CCH62781.1 - 5.4e-52 175.8 0.1 1.1e-51 174.8 0.1 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit UTP15_C PF09384.10 CCH62782.1 - 2.6e-44 150.4 0.5 4.3e-44 149.8 0.5 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CCH62782.1 - 3.3e-16 59.4 5.5 0.029 15.2 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62782.1 - 3.5e-06 27.2 0.0 0.16 12.3 0.0 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CCH62782.1 - 0.018 15.0 0.0 3 7.9 0.0 3.9 1 1 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region DUF5122 PF17164.4 CCH62782.1 - 0.11 12.8 0.1 0.5 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Drc1-Sld2 PF11719.8 CCH62783.1 - 5.1e-39 135.1 43.8 1.2e-36 127.2 43.8 2.2 1 1 0 1 1 1 1 DNA replication and checkpoint protein Lipid_DES PF08557.10 CCH62783.1 - 0.068 12.7 1.2 0.17 11.4 1.2 1.6 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Apc13p PF05839.11 CCH62783.1 - 0.83 9.9 4.8 2.8 8.2 0.6 2.6 2 0 0 2 2 2 0 Apc13p protein E7 PF00527.18 CCH62783.1 - 5.1 7.4 9.0 9.5 6.5 1.2 2.7 2 0 0 2 2 2 0 E7 protein, Early protein MMR_HSR1 PF01926.23 CCH62785.1 - 3e-12 46.6 0.0 9.2e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH62785.1 - 3.9e-08 33.4 0.1 6.9e-08 32.6 0.1 1.4 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CCH62785.1 - 0.00083 18.9 0.1 0.0019 17.8 0.1 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 CCH62785.1 - 0.0026 18.3 0.7 0.018 15.6 0.0 2.5 2 1 1 3 3 3 1 AAA domain IIGP PF05049.13 CCH62785.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 CCH62785.1 - 0.018 14.8 0.0 0.069 12.9 0.0 2.0 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 CCH62785.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 CCH62785.1 - 0.042 13.6 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CCH62785.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 CCH62785.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCH62785.1 - 0.093 12.6 0.1 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 CCH62785.1 - 0.1 13.0 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Methyltrn_RNA_4 PF09936.9 CCH62785.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase ABC_tran PF00005.27 CCH62785.1 - 0.14 12.6 0.2 0.34 11.4 0.0 1.7 1 1 1 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 CCH62785.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain KTI12 PF08433.10 CCH62786.1 - 1.3e-89 300.3 0.4 1.5e-89 300.1 0.4 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 CCH62786.1 - 0.00033 20.6 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCH62786.1 - 0.00044 20.4 0.0 0.00094 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH62786.1 - 0.0056 17.2 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCH62786.1 - 0.021 15.1 0.0 0.24 11.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CCH62786.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.12 CCH62786.1 - 0.14 12.0 0.1 3.8 7.3 0.0 2.4 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RasGEF_N PF00618.20 CCH62786.1 - 0.19 12.0 2.0 1.8 8.8 0.2 2.5 2 1 0 2 2 2 0 RasGEF N-terminal motif RsfS PF02410.15 CCH62787.1 - 5.2e-19 68.5 0.0 1.7e-18 66.9 0.0 2.0 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 CCH62787.1 - 4.6e-16 58.6 16.1 8.7e-16 57.7 16.1 1.5 1 0 0 1 1 1 1 mRNA stabilisation DUF3399 PF11879.8 CCH62787.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) BAF1_ABF1 PF04684.13 CCH62788.1 - 3.4e-195 650.3 110.0 6.5e-193 642.8 110.0 3.6 1 1 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CCH62788.1 - 0.00066 19.6 0.4 0.0018 18.2 0.2 1.8 2 0 0 2 2 2 1 MuDR family transposase TM1586_NiRdase PF14512.6 CCH62788.1 - 0.89 9.1 9.1 0.025 14.2 2.5 1.7 2 0 0 2 2 2 0 Putative TM nitroreductase XPG_N PF00752.17 CCH62789.1 - 6.8e-39 132.4 1.2 7.3e-39 132.3 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 CCH62789.1 - 6.8e-28 96.9 0.4 4.1e-27 94.4 0.0 2.4 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CCH62789.1 - 2.8e-07 31.0 4.2 4.1e-07 30.5 0.0 2.9 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 CCH62789.1 - 0.00042 20.4 0.1 0.0032 17.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CCH62789.1 - 0.00053 20.5 0.0 0.0032 18.0 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.16 CCH62789.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain HXXSHH PF07586.11 CCH62789.1 - 0.11 12.0 1.2 0.22 11.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Transposase_20 PF02371.16 CCH62789.1 - 0.14 12.5 0.0 0.49 10.8 0.0 2.0 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Rrp15p PF07890.12 CCH62789.1 - 0.54 10.6 11.5 1.2 9.5 1.1 2.3 2 0 0 2 2 2 0 Rrp15p AP_endonuc_2 PF01261.24 CCH62790.1 - 3.7e-28 98.4 0.0 5.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DCX PF03607.17 CCH62790.1 - 0.086 13.0 0.0 0.38 10.9 0.0 2.1 1 1 0 1 1 1 0 Doublecortin Pkinase PF00069.25 CCH62791.1 - 2.3e-41 141.9 0.0 3.5e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62791.1 - 1.2e-19 70.7 0.0 6.2e-19 68.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCH62791.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldose_epim PF01263.20 CCH62792.1 - 5.2e-47 160.6 0.4 6.3e-47 160.3 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-MYND PF01753.18 CCH62794.1 - 3.5e-08 33.4 18.0 6.8e-08 32.5 18.0 1.5 1 0 0 1 1 1 1 MYND finger SPRY PF00622.28 CCH62795.1 - 1.3e-10 41.4 0.0 3.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Cwf_Cwc_15 PF04889.12 CCH62795.1 - 0.071 12.8 0.2 0.071 12.8 0.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FimH_man-bind PF09160.10 CCH62795.1 - 0.29 10.8 3.0 0.31 10.7 0.9 2.1 2 0 0 2 2 2 0 FimH, mannose binding RRN3 PF05327.11 CCH62796.1 - 1.8e-183 611.1 13.0 2.2e-183 610.8 13.0 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 CCH62796.1 - 0.001 17.5 7.3 0.0017 16.8 7.3 1.3 1 0 0 1 1 1 1 CDC45-like protein GCIP PF13324.6 CCH62796.1 - 0.0012 18.5 6.4 0.0012 18.5 6.4 1.9 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting DNA_pol_phi PF04931.13 CCH62796.1 - 0.32 9.1 28.9 0.0092 14.1 20.0 2.6 3 0 0 3 3 3 0 DNA polymerase phi DUF1539 PF07560.11 CCH62796.1 - 0.57 10.3 9.2 0.21 11.7 0.6 3.8 2 2 0 2 2 2 0 Domain of Unknown Function (DUF1539) Nop53 PF07767.11 CCH62796.1 - 0.73 9.2 11.0 1.2 8.5 11.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DASH_Dad3 PF08656.10 CCH62796.1 - 1.1 9.4 4.4 24 5.1 1.2 3.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 Sigma70_ner PF04546.13 CCH62796.1 - 1.2 9.0 17.4 3 7.7 17.4 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF3385 PF11865.8 CCH62796.1 - 2.5 8.0 9.5 1.3 8.9 0.8 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF3385) CobT PF06213.12 CCH62796.1 - 5.9 6.2 17.7 9.3 5.5 17.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 CCH62796.1 - 8.8 5.4 12.6 16 4.6 12.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 CCH62797.1 - 1.2e-68 231.4 0.0 2.7e-68 230.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62797.1 - 4.2e-30 104.9 0.0 1e-29 103.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCH62797.1 - 3.2e-11 43.7 0.3 1.7e-10 41.4 0.3 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCH62797.1 - 0.0001 21.4 0.2 0.0001 21.4 0.2 2.5 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 CCH62797.1 - 0.0062 16.2 0.5 2.5 7.7 0.1 2.9 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CCH62797.1 - 0.018 14.4 0.0 0.057 12.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CCH62797.1 - 0.052 12.9 0.2 0.11 11.8 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGM_PMM_I PF02878.16 CCH62798.1 - 7.8e-35 119.6 0.1 1.5e-34 118.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CCH62798.1 - 1.5e-24 86.4 0.0 2.6e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCH62798.1 - 4.3e-14 53.0 0.0 1.3e-13 51.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CCH62798.1 - 0.00023 21.2 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPG4 PF17325.2 CCH62799.1 - 9.3e-41 139.3 4.2 1.1e-40 139.2 4.2 1.0 1 0 0 1 1 1 1 Stationary phase protein 4 TPP_enzyme_N PF02776.18 CCH62800.1 - 5.4e-58 195.4 0.1 2.2e-57 193.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCH62800.1 - 2.5e-50 170.2 0.0 1.5e-48 164.4 0.1 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCH62800.1 - 4.4e-40 136.6 0.4 1.2e-39 135.1 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 CCH62800.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Glyco_tran_WecB PF03808.13 CCH62800.1 - 0.17 11.8 0.0 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family PIR PF00399.19 CCH62801.1 - 3.6e-39 131.5 82.8 7.8e-09 34.9 7.6 6.4 6 0 0 6 6 6 5 Yeast PIR protein repeat KAR9 PF08580.10 CCH62801.1 - 0.13 10.8 7.9 0.16 10.5 7.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TFIIA PF03153.13 CCH62801.1 - 5.6 6.9 15.7 6.1 6.7 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_head PF00063.21 CCH62802.1 - 6.7e-231 768.2 8.1 8.9e-231 767.8 8.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CCH62802.1 - 3.2e-38 131.3 0.0 5.3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CCH62802.1 - 7.3e-10 38.3 0.0 1.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH62802.1 - 1.3e-06 28.2 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 CCH62802.1 - 0.02 15.3 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CCH62802.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCH62802.1 - 0.034 14.6 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Hpr_kinase_C PF07475.12 CCH62802.1 - 0.058 12.9 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 CCH62802.1 - 0.076 12.9 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 CCH62802.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CCH62802.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IQ PF00612.27 CCH62802.1 - 0.21 11.5 8.8 0.8 9.7 1.1 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif TFIIE_alpha PF02002.17 CCH62803.1 - 7.6e-35 119.0 0.2 3e-34 117.0 0.0 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 CCH62803.1 - 1.7e-11 43.4 0.7 5.9e-11 41.7 0.7 2.0 1 0 0 1 1 1 1 TFIIB zinc-binding Malic_M PF03949.15 CCH62804.1 - 3.7e-74 249.3 0.0 4.8e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CCH62804.1 - 2.7e-65 219.6 0.0 4.1e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain RPM2 PF08579.11 CCH62804.1 - 0.069 13.6 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) NIF PF03031.18 CCH62805.1 - 1.1e-48 165.0 0.1 1.5e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PGP_phosphatase PF09419.10 CCH62805.1 - 0.19 11.3 0.7 13 5.4 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial PGP phosphatase zf-C2H2 PF00096.26 CCH62807.1 - 1.4e-05 25.2 4.1 1.4e-05 25.2 4.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH62807.1 - 0.0024 18.6 4.7 0.0024 18.6 4.7 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 CCH62807.1 - 0.0026 18.0 5.9 0.0052 17.1 5.9 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CCH62807.1 - 0.076 13.4 8.3 0.52 10.7 0.8 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CCH62807.1 - 0.8 10.2 0.1 0.8 10.2 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 CCH62807.1 - 5.1 7.6 18.5 1.1 9.7 2.7 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-rbx1 PF12678.7 CCH62808.1 - 1.1e-08 35.3 5.7 1.8e-08 34.5 5.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCH62808.1 - 3e-08 33.9 8.8 9.6e-08 32.2 8.8 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCH62808.1 - 3.8e-07 29.8 2.5 3.8e-07 29.8 2.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH62808.1 - 5.4e-07 29.5 4.2 9e-07 28.8 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CCH62808.1 - 2.9e-05 23.7 5.4 0.0011 18.7 0.7 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 CCH62808.1 - 4.1e-05 23.4 7.4 7.9e-05 22.5 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCH62808.1 - 7.4e-05 22.5 2.5 0.00016 21.4 2.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CCH62808.1 - 0.00057 19.8 4.9 0.0014 18.6 4.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCH62808.1 - 0.00085 19.1 5.8 0.0031 17.3 5.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCH62808.1 - 0.0015 18.1 1.7 0.0015 18.1 1.7 1.6 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CCH62808.1 - 0.0021 18.1 2.0 0.0047 17.0 2.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Lact_bio_phlase PF09508.10 CCH62808.1 - 0.024 13.1 0.1 0.047 12.1 0.1 1.4 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain FANCL_C PF11793.8 CCH62808.1 - 0.062 13.5 6.6 0.25 11.5 6.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3490 PF11995.8 CCH62808.1 - 0.068 13.0 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) zf-RING_6 PF14835.6 CCH62808.1 - 0.18 11.7 1.6 0.58 10.1 0.2 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-C3H2C3 PF17122.5 CCH62808.1 - 0.37 10.9 3.0 0.98 9.5 3.0 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CCH62808.1 - 0.63 10.2 5.1 0.37 10.9 2.2 2.0 2 0 0 2 2 2 0 RING-variant domain zf-P11 PF03854.14 CCH62808.1 - 1.6 8.5 6.2 0.37 10.5 2.4 1.9 2 0 0 2 2 2 0 P-11 zinc finger Herpes_UL73 PF03554.13 CCH62808.1 - 2 8.5 5.2 0.98 9.5 0.6 2.9 3 0 0 3 3 3 0 UL73 viral envelope glycoprotein Pribosyl_synth PF14572.6 CCH62809.1 - 1.1e-40 139.7 2.6 6.3e-35 120.9 1.6 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CCH62809.1 - 2.2e-40 137.2 0.1 1.2e-38 131.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CCH62809.1 - 9.1e-16 57.8 1.2 1.9e-15 56.7 1.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCH62809.1 - 0.0094 15.4 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase MSG PF02349.15 CCH62810.1 - 0.69 10.1 4.1 2.8 8.2 4.1 2.1 1 0 0 1 1 1 0 Major surface glycoprotein Form_Nir_trans PF01226.17 CCH62811.1 - 3.2e-51 174.0 20.2 4e-51 173.6 20.2 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Ycf1 PF05758.12 CCH62811.1 - 0.41 8.4 2.4 0.77 7.6 2.4 1.3 1 0 0 1 1 1 0 Ycf1 Cyt-b5 PF00173.28 CCH62812.1 - 2.7e-19 69.1 0.0 4.6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CCDC85 PF10226.9 CCH62812.1 - 0.097 12.3 0.7 0.15 11.7 0.7 1.3 1 0 0 1 1 1 0 CCDC85 family UDPGP PF01704.18 CCH62813.1 - 1.3e-187 623.6 0.7 1.5e-187 623.3 0.7 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Opi1 PF08618.10 CCH62814.1 - 3.2e-15 56.3 29.0 2.5e-07 30.3 0.0 4.6 3 2 1 4 4 4 3 Transcription factor Opi1 KLRAQ PF10205.9 CCH62814.1 - 0.1 12.8 0.4 0.1 12.8 0.4 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein Snf7 PF03357.21 CCH62815.1 - 1.3e-32 112.8 19.6 1.3e-32 112.8 19.6 1.9 2 0 0 2 2 2 1 Snf7 Eno-Rase_FAD_bd PF07055.12 CCH62815.1 - 0.03 14.7 2.2 0.03 14.7 2.2 2.3 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF489 PF04356.12 CCH62815.1 - 0.1 12.6 9.8 0.44 10.5 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) CLU PF13236.6 CCH62816.1 - 1.5e-60 204.8 0.1 3.5e-60 203.6 0.1 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CCH62816.1 - 4.3e-34 118.1 0.0 1.6e-32 113.0 0.0 3.3 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CCH62816.1 - 1.9e-22 79.4 1.4 1.9e-22 79.4 1.4 3.1 4 0 0 4 4 4 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 CCH62816.1 - 1.5e-06 28.4 0.0 0.098 13.0 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat DUF727 PF05303.12 CCH62816.1 - 0.0028 17.7 0.1 0.015 15.3 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_10 PF13374.6 CCH62816.1 - 0.035 14.0 0.0 3.2 7.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SecE PF00584.20 CCH62817.1 - 0.007 16.3 0.4 0.038 13.9 0.4 2.3 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex GTP_EFTU PF00009.27 CCH62818.1 - 1.1e-21 77.3 0.1 1.1e-21 77.3 0.1 2.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CCH62818.1 - 0.00021 21.6 0.7 0.00056 20.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 AAA_29 PF13555.6 CCH62818.1 - 0.00063 19.4 0.2 0.0033 17.1 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 CCH62818.1 - 0.0031 17.6 0.0 0.0031 17.6 0.0 3.1 2 1 1 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 CCH62818.1 - 0.0035 17.3 0.7 0.015 15.2 0.2 2.2 2 0 0 2 2 2 1 RsgA GTPase Roc PF08477.13 CCH62818.1 - 0.0037 17.5 0.9 0.34 11.1 0.1 3.5 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CCH62818.1 - 0.0042 16.5 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family T2SSE PF00437.20 CCH62818.1 - 0.0049 16.0 0.1 0.027 13.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 CCH62818.1 - 0.03 14.9 0.0 0.13 12.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCH62818.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCH62818.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCH62818.1 - 0.061 13.8 0.1 0.061 13.8 0.1 3.3 2 2 1 3 3 2 0 ABC transporter NACHT PF05729.12 CCH62818.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 CCH62818.1 - 0.074 13.1 1.9 0.21 11.7 0.1 2.8 3 1 0 3 3 3 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CCH62818.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 HA2 PF04408.23 CCH62819.1 - 3.1e-21 75.7 0.0 1e-20 74.0 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCH62819.1 - 3.7e-14 53.0 0.6 1.8e-13 50.8 0.1 2.5 3 0 0 3 3 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCH62819.1 - 3.5e-13 49.7 0.0 3.5e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCH62819.1 - 9e-10 38.6 0.2 2.5e-09 37.1 0.2 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCH62819.1 - 5.7e-07 29.9 0.1 3.7e-06 27.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCH62819.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH62819.1 - 0.00012 22.5 0.1 0.00031 21.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CCH62819.1 - 0.00015 21.2 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CCH62819.1 - 0.002 17.9 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 CCH62819.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CCH62819.1 - 0.0023 17.8 0.1 0.71 9.7 0.0 3.0 2 1 1 3 3 3 1 Helicase AAA_14 PF13173.6 CCH62819.1 - 0.012 15.6 1.1 0.71 9.9 1.1 3.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCH62819.1 - 0.02 14.6 0.1 0.049 13.2 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 CCH62819.1 - 0.029 13.7 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 CCH62819.1 - 0.055 14.0 0.0 0.24 11.9 0.0 2.1 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 CCH62819.1 - 0.055 13.5 3.7 0.076 13.0 0.2 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CCH62819.1 - 0.062 12.7 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 CCH62819.1 - 0.074 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 CCH62819.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF3336 PF11815.8 CCH62820.1 - 2.8e-30 104.9 6.6 2.8e-30 104.9 6.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCH62820.1 - 6.2e-25 88.6 0.2 2.8e-24 86.4 0.0 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase Abhydrolase_6 PF12697.7 CCH62822.1 - 4.4e-12 47.1 0.0 6.3e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCH62822.1 - 7.9e-06 25.7 0.1 0.0017 18.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold LIDHydrolase PF10230.9 CCH62822.1 - 0.0011 18.6 0.2 0.052 13.1 0.1 2.4 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 CCH62822.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein RuvB_C PF05491.13 CCH62822.1 - 0.0044 16.9 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 RuvB C-terminal winged helix domain Hydrolase_4 PF12146.8 CCH62822.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 CCH62822.1 - 0.061 13.0 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Desmo_N PF06771.11 CCH62822.1 - 0.16 12.4 4.5 7 7.1 0.5 3.2 2 1 1 3 3 3 0 Viral Desmoplakin N-terminus ERCC3_RAD25_C PF16203.5 CCH62823.1 - 1.2e-125 417.7 0.9 2.3e-125 416.8 0.9 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CCH62823.1 - 1.7e-35 121.9 0.0 4.4e-35 120.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH62823.1 - 1.4e-16 61.0 0.1 4.8e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCH62823.1 - 5.2e-12 46.1 0.1 1.4e-11 44.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CCH62823.1 - 2.5e-09 36.3 0.0 3.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CCH62823.1 - 3.6e-05 23.6 0.0 8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 CCH62823.1 - 0.038 13.4 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Ndc80_HEC PF03801.13 CCH62824.1 - 1.5e-48 164.3 0.3 6.9e-48 162.2 0.1 2.2 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 CCH62824.1 - 3.2e-07 30.3 3.6 3.2e-07 30.3 3.6 6.3 6 1 1 7 7 7 2 Domain of unknown function (DUF5595) Jnk-SapK_ap_N PF09744.9 CCH62824.1 - 3.5 7.8 46.4 0.26 11.5 20.1 3.3 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Pantoate_ligase PF02569.15 CCH62825.1 - 5.7e-96 320.8 0.0 6.4e-96 320.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CTP_transf_like PF01467.26 CCH62825.1 - 0.024 14.8 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase-like FAD_syn PF06574.12 CCH62825.1 - 0.033 14.1 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD synthetase Response_reg PF00072.24 CCH62826.1 - 2.4e-27 95.3 1.1 4.8e-27 94.4 0.3 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 CCH62826.1 - 4.4e-27 94.8 0.3 1.3e-20 73.9 0.1 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CCH62826.1 - 1.1e-11 44.6 0.1 3.2e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CCH62826.1 - 0.00061 20.1 0.1 0.42 11.0 0.0 2.5 2 0 0 2 2 2 2 HAMP domain NPF PF16601.5 CCH62827.1 - 0.26 11.7 2.4 0.27 11.7 1.1 1.7 1 1 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif Myb_DNA-bind_6 PF13921.6 CCH62828.1 - 6.1e-28 96.8 3.8 2.9e-10 40.2 0.4 3.7 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CCH62828.1 - 3.4e-27 94.4 10.8 7.4e-12 45.3 0.1 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CCH62828.1 - 0.00024 21.1 2.7 4.1 7.5 0.0 4.0 2 1 2 4 4 4 2 SLIDE Rap1_C PF11626.8 CCH62828.1 - 0.00056 19.9 0.0 0.44 10.7 0.0 3.2 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 CCH62828.1 - 0.2 11.9 2.6 20 5.5 0.0 3.8 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 DUF1748 PF08520.10 CCH62829.1 - 3.8e-29 100.4 0.0 4.2e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) FG-GAP_2 PF14312.6 CCH62829.1 - 0.15 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 FG-GAP repeat DUF4639 PF15479.6 CCH62830.1 - 0.37 9.7 1.9 0.52 9.2 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) G10 PF01125.17 CCH62830.1 - 3 7.6 9.7 0.82 9.4 0.5 2.9 3 1 0 3 3 3 0 G10 protein Endomucin PF07010.12 CCH62830.1 - 4 7.3 25.7 0.77 9.7 16.5 2.4 3 0 0 3 3 3 0 Endomucin GalP_UDP_tr_C PF02744.17 CCH62831.1 - 3.5e-67 225.3 1.5 3.6e-67 225.2 0.4 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CCH62831.1 - 1.6e-66 224.3 0.0 2.2e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 CCH62831.1 - 0.018 15.7 0.0 0.14 12.9 0.0 2.2 2 0 0 2 2 2 0 HIT domain WG_beta_rep PF14903.6 CCH62831.1 - 0.089 13.1 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 WG containing repeat DUF4921 PF16268.5 CCH62831.1 - 0.16 10.8 0.3 8 5.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) DUF3721 PF12518.8 CCH62831.1 - 0.31 10.9 1.6 0.9 9.4 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function Aldose_epim PF01263.20 CCH62832.1 - 5.4e-77 259.1 0.3 8.1e-77 258.5 0.3 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 CCH62832.1 - 2.2e-56 191.7 0.0 9.3e-56 189.6 0.0 2.0 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CCH62832.1 - 2.7e-54 184.2 0.0 7.6e-54 182.7 0.0 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CCH62832.1 - 1.3e-19 70.5 0.0 1e-17 64.2 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CCH62832.1 - 1.1e-16 60.6 0.0 6.7e-16 58.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CCH62832.1 - 3.6e-10 39.4 0.0 6.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CCH62832.1 - 8e-08 31.7 0.0 6.6e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CCH62832.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCH62832.1 - 8.8e-07 29.0 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CCH62832.1 - 5.1e-06 26.5 0.0 9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCH62832.1 - 0.029 13.9 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family TrkA_N PF02254.18 CCH62832.1 - 0.069 13.4 0.2 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain GalKase_gal_bdg PF10509.9 CCH62833.1 - 1.7e-21 75.5 0.0 4.6e-21 74.1 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CCH62833.1 - 3e-16 59.4 0.2 7.4e-16 58.1 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCH62833.1 - 9.7e-14 51.5 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1748 PF08520.10 CCH62833.1 - 0.016 15.1 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) ABC2_membrane PF01061.24 CCH62834.1 - 1.1e-59 201.5 69.1 2.3e-36 125.2 15.0 3.0 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCH62834.1 - 3.2e-36 124.9 0.0 6.2e-17 62.4 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CCH62834.1 - 9.9e-30 102.3 18.2 5.7e-29 99.9 0.0 4.1 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CCH62834.1 - 4.9e-14 52.2 5.9 4.9e-14 52.2 5.9 3.2 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC_trans_N PF14510.6 CCH62834.1 - 3e-07 31.0 1.2 3e-07 31.0 1.2 2.3 2 1 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCH62834.1 - 2e-06 27.8 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CCH62834.1 - 6.4e-05 23.4 0.1 0.0045 17.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CCH62834.1 - 0.0013 18.4 0.1 0.19 11.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CCH62834.1 - 0.0015 18.3 0.2 0.17 11.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCH62834.1 - 0.0015 18.4 2.1 1.3 8.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CCH62834.1 - 0.0019 18.2 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCH62834.1 - 0.0029 17.9 0.7 0.015 15.6 0.2 2.5 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 CCH62834.1 - 0.0032 16.9 0.0 0.57 9.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 CCH62834.1 - 0.011 15.8 0.9 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 CCH62834.1 - 0.011 15.3 1.4 0.039 13.6 0.1 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CCH62834.1 - 0.021 15.4 0.3 0.12 12.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCH62834.1 - 0.036 13.7 0.0 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CCH62834.1 - 0.054 14.0 1.8 0.53 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCH62834.1 - 0.11 12.3 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCH62834.1 - 0.14 12.1 0.6 0.54 10.2 0.1 2.1 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 CCH62834.1 - 0.2 11.7 0.4 0.94 9.5 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Macro PF01661.21 CCH62835.1 - 8.4e-26 90.3 0.0 1.9e-25 89.2 0.0 1.5 1 1 0 1 1 1 1 Macro domain IL4 PF00727.18 CCH62835.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Interleukin 4 SCO1-SenC PF02630.14 CCH62836.1 - 2.4e-45 153.8 0.1 3.4e-45 153.3 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CCH62836.1 - 0.0012 18.8 0.3 0.013 15.5 0.3 2.4 1 1 0 1 1 1 1 AhpC/TSA family CSG2 PF16965.5 CCH62837.1 - 1.6e-117 392.8 13.3 1.8e-117 392.7 13.3 1.0 1 0 0 1 1 1 1 Ceramide synthase regulator DUF2207 PF09972.9 CCH62837.1 - 0.052 12.3 3.1 1.5 7.5 3.1 2.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FixQ PF05545.11 CCH62837.1 - 0.64 10.0 0.0 0.64 10.0 0.0 3.1 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Sigma_reg_N PF13800.6 CCH62837.1 - 1.9 8.8 0.0 1.9 8.8 0.0 4.0 4 1 1 5 5 5 0 Sigma factor regulator N-terminal Pkinase PF00069.25 CCH62838.1 - 1.5e-62 211.3 0.2 1.1e-60 205.3 0.2 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62838.1 - 6.7e-30 104.2 0.1 2.8e-20 72.7 0.1 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCH62838.1 - 0.0012 18.2 0.1 0.096 12.0 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 CCH62838.1 - 0.06 14.1 6.7 0.26 12.0 6.7 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain DASH_Dad1 PF08649.10 CCH62839.1 - 5.9e-20 71.2 0.2 7.4e-20 70.9 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 GCR1_C PF12550.8 CCH62839.1 - 0.0053 17.0 0.1 1.5 9.2 0.0 2.1 2 0 0 2 2 2 2 Transcriptional activator of glycolytic enzymes DUF4283 PF14111.6 CCH62839.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) IPK PF03770.16 CCH62840.1 - 3.3e-47 160.9 0.1 3.3e-47 160.9 0.1 3.3 3 0 0 3 3 3 1 Inositol polyphosphate kinase Fig1 PF12351.8 CCH62841.1 - 5.5e-47 160.1 5.2 5.5e-47 160.1 5.2 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 CitMHS PF03600.16 CCH62841.1 - 0.062 12.5 3.7 1.9 7.6 1.8 2.1 2 0 0 2 2 2 0 Citrate transporter MARVEL PF01284.23 CCH62841.1 - 0.33 11.0 11.8 2.7 8.0 11.8 2.2 1 1 0 1 1 1 0 Membrane-associating domain ODV-E18 PF10717.9 CCH62841.1 - 9.9 6.1 8.1 14 5.6 0.3 3.0 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 AMP-binding PF00501.28 CCH62842.1 - 6.3e-18 64.6 0.0 5.1e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Acyltransferase PF01553.21 CCH62843.1 - 5.9e-29 100.4 0.0 1.1e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CCH62843.1 - 1.4e-13 50.7 0.5 2.4e-13 50.0 0.1 1.7 2 0 0 2 2 2 1 Acyltransferase C-terminus Spermine_synth PF01564.17 CCH62843.1 - 0.098 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase domain DEAD PF00270.29 CCH62844.1 - 8.4e-44 149.4 2.1 1.5e-43 148.6 2.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH62844.1 - 1.2e-33 115.8 1.4 1.1e-31 109.4 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCH62844.1 - 9.1e-07 29.0 0.4 1.8e-06 28.1 0.1 1.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCH62844.1 - 0.00013 21.7 0.1 0.00026 20.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCH62844.1 - 0.00028 21.2 0.2 0.00084 19.7 0.1 1.8 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 CCH62844.1 - 0.00062 19.2 0.1 0.0027 17.1 0.0 2.0 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 CCH62844.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.6 CCH62844.1 - 0.0041 17.4 0.5 0.012 15.9 0.5 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 CCH62844.1 - 0.008 15.7 3.0 0.058 12.8 3.0 2.2 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 CCH62844.1 - 0.019 14.5 0.2 0.025 14.1 0.2 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CobA_CobO_BtuR PF02572.15 CCH62844.1 - 0.03 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.14 CCH62844.1 - 0.058 13.4 0.0 0.22 11.5 0.0 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain TniB PF05621.11 CCH62844.1 - 0.072 12.5 0.1 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein BATS PF06968.13 CCH62844.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain RNA_pol_Rpc4 PF05132.14 CCH62845.1 - 2.4 8.6 12.6 0.74 10.2 4.8 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 PRP1_N PF06424.12 CCH62845.1 - 6.9 7.1 25.4 1.4 9.3 12.0 2.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF1752 PF08550.10 CCH62846.1 - 0.00095 19.0 1.4 0.002 17.9 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans_2 PF11951.8 CCH62847.1 - 1.3e-18 67.0 1.4 2.7e-18 66.0 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCH62847.1 - 4.8e-06 26.6 12.6 8.3e-06 25.8 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.12 CCH62848.1 - 7.3e-27 94.6 6.9 7.3e-27 94.6 6.9 2.3 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 CCH62848.1 - 1.2e-08 35.4 0.1 0.0051 17.3 0.0 5.9 6 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCH62848.1 - 3.1e-07 30.7 0.0 2.7 9.0 0.0 7.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH62848.1 - 0.00015 21.9 0.0 1 9.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62848.1 - 0.00066 19.6 0.2 1.8 8.9 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62848.1 - 0.039 14.2 11.4 6.8 7.2 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH62848.1 - 0.059 13.6 0.3 2 8.7 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 CCH62848.1 - 0.089 12.8 4.3 4.9 7.2 0.9 4.1 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 CCH62848.1 - 0.16 12.7 0.0 1.8 9.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3347 PF11827.8 CCH62848.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3347) CYSTM PF12734.7 CCH62849.1 - 3.5e-07 30.4 7.5 3.5e-07 30.4 7.5 2.8 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Wtap PF17098.5 CCH62850.1 - 9.3e-09 35.4 10.8 9.3e-09 35.4 10.8 2.0 2 2 0 2 2 2 1 WTAP/Mum2p family Pkinase PF00069.25 CCH62852.1 - 6.3e-35 120.8 0.4 1.4e-34 119.7 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62852.1 - 2.5e-22 79.4 0.1 3.9e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FtsJ PF01728.19 CCH62853.1 - 3.9e-66 222.5 0.0 5e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ribosomal_S10 PF00338.22 CCH62854.1 - 1.1e-26 92.9 0.0 3e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.6 CCH62855.1 - 4.2e-10 39.8 10.8 5.8e-10 39.3 8.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CCH62855.1 - 4e-08 33.4 8.1 2e-07 31.2 8.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCH62855.1 - 3e-07 30.4 4.1 8.1e-07 29.0 3.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CCH62855.1 - 0.00015 21.7 3.7 0.00015 21.7 3.7 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CCH62855.1 - 0.00025 20.8 8.3 0.00025 20.8 8.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCH62855.1 - 0.00057 19.7 8.0 0.00057 19.7 8.0 1.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCH62855.1 - 0.00098 19.0 6.0 0.00098 19.0 6.0 1.7 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCH62855.1 - 0.0019 18.0 6.9 0.0052 16.6 6.8 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCH62855.1 - 0.0044 16.7 5.0 0.0044 16.7 5.0 2.4 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 CCH62855.1 - 0.01 15.7 7.3 0.04 13.8 7.3 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 GET2 PF08690.10 CCH62855.1 - 0.037 13.7 5.0 0.048 13.3 5.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 zf-P11 PF03854.14 CCH62855.1 - 0.061 13.0 8.3 0.19 11.4 8.3 1.8 1 1 1 2 2 2 0 P-11 zinc finger FANCL_C PF11793.8 CCH62855.1 - 0.11 12.7 6.4 0.85 9.8 6.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RRN7 PF11781.8 CCH62855.1 - 0.29 10.8 2.4 2 8.2 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-Nse PF11789.8 CCH62855.1 - 0.33 10.8 4.9 0.19 11.5 2.4 2.0 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CCH62855.1 - 0.34 11.1 6.2 0.44 10.7 5.1 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 CCH62855.1 - 4.3 7.6 8.7 20 5.4 8.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2 PF00096.26 CCH62856.1 - 6e-05 23.3 17.4 0.0011 19.3 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH62856.1 - 7e-05 23.1 2.2 7e-05 23.1 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH62856.1 - 0.00082 20.0 13.8 0.02 15.7 1.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCH62856.1 - 0.02 15.3 1.0 0.02 15.3 1.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING-like PF08746.11 CCH62856.1 - 4.1 7.8 9.1 0.53 10.6 3.8 2.0 2 0 0 2 2 2 0 RING-like domain TFIIS_C PF01096.18 CCH62857.1 - 4.7e-22 77.6 1.2 4.7e-22 77.6 1.2 2.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCH62857.1 - 1.6e-12 47.0 3.0 6.7e-12 45.1 0.6 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CCH62857.1 - 0.0012 18.8 3.9 0.42 10.6 0.4 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Elf1 PF05129.13 CCH62857.1 - 0.0077 16.3 3.7 0.052 13.6 0.2 2.4 2 1 0 2 2 2 1 Transcription elongation factor Elf1 like DpnI PF06044.12 CCH62857.1 - 0.035 13.7 0.5 0.035 13.7 0.5 1.7 1 1 1 2 2 2 0 Dam-replacing family Lar_restr_allev PF14354.6 CCH62857.1 - 0.071 13.5 4.7 18 5.8 4.7 2.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar Baculo_LEF5_C PF11792.8 CCH62857.1 - 0.073 12.8 3.1 0.38 10.5 0.1 2.8 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain IBR PF01485.21 CCH62857.1 - 0.13 12.5 10.1 0.91 9.8 0.6 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zinc_ribbon_10 PF10058.9 CCH62857.1 - 0.18 11.6 5.9 3.9 7.3 0.1 3.0 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 CCH62857.1 - 0.72 9.9 6.6 3.4 7.7 0.3 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-piccolo PF05715.13 CCH62857.1 - 2 8.6 9.5 0.45 10.7 2.0 2.8 3 0 0 3 3 3 0 Piccolo Zn-finger zinc_ribbon_5 PF13719.6 CCH62857.1 - 4.6 7.1 5.8 3.3 7.5 0.3 3.0 3 1 0 3 3 3 0 zinc-ribbon domain AA_permease PF00324.21 CCH62858.1 - 1.3e-120 403.2 40.7 1.6e-120 403.0 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH62858.1 - 6.3e-31 107.6 42.3 8.4e-31 107.2 42.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCH62859.1 - 5.2e-121 404.6 31.5 6.4e-121 404.3 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCH62859.1 - 6e-39 134.1 31.1 7.8e-39 133.7 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease Thioredoxin PF00085.20 CCH62860.1 - 0.00035 20.5 0.0 0.00044 20.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 CCH62860.1 - 0.0029 17.6 0.2 0.0043 17.0 0.2 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CCH62860.1 - 0.011 16.2 0.0 0.041 14.3 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CCH62860.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain His_Phos_1 PF00300.22 CCH62861.1 - 1.5e-25 90.0 0.0 2.2e-14 53.6 0.0 3.1 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) TIM PF00121.18 CCH62862.1 - 2.6e-89 298.8 1.1 3e-89 298.6 1.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MreB_Mbl PF06723.13 CCH62862.1 - 0.013 14.4 0.8 0.089 11.6 0.0 2.2 2 1 0 2 2 2 0 MreB/Mbl protein Alg14 PF08660.11 CCH62863.1 - 2.6e-52 177.3 0.1 3.5e-52 176.8 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like zf-C2H2 PF00096.26 CCH62864.1 - 9.5e-09 35.2 11.5 0.00053 20.3 1.8 3.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCH62864.1 - 0.00019 22.0 9.8 0.044 14.6 1.1 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCH62864.1 - 0.00044 20.5 3.6 0.31 11.5 0.5 3.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CCH62864.1 - 0.00086 19.6 0.4 0.00086 19.6 0.4 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 CCH62864.1 - 0.024 14.9 12.8 0.093 13.0 0.6 3.6 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CCH62864.1 - 1.9 8.9 8.5 1.1 9.7 0.6 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CCH62864.1 - 8.4 6.5 10.1 0.25 11.4 2.0 2.8 2 0 0 2 2 2 0 BED zinc finger zf-DBF PF07535.12 CCH62865.1 - 1.3e-14 54.0 2.3 1.3e-14 54.0 2.3 3.3 4 0 0 4 4 4 1 DBF zinc finger Presenilin PF01080.17 CCH62865.1 - 7.3 5.2 8.6 10 4.7 8.6 1.1 1 0 0 1 1 1 0 Presenilin Recep_L_domain PF01030.24 CCH62866.1 - 4.2e-08 33.3 7.1 0.0029 17.7 0.2 4.6 1 1 4 5 5 5 3 Receptor L domain CPSF100_C PF13299.6 CCH62866.1 - 0.0082 16.3 1.4 0.021 15.0 1.4 1.7 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal LRR_9 PF14580.6 CCH62866.1 - 0.11 12.0 0.4 0.21 11.0 0.4 1.6 1 0 0 1 1 1 0 Leucine-rich repeat Macoilin PF09726.9 CCH62866.1 - 0.28 9.7 15.7 0.45 9.0 15.7 1.3 1 0 0 1 1 1 0 Macoilin family Ima1_N PF09779.9 CCH62866.1 - 1.4 9.8 5.0 3.1 8.7 5.0 1.5 1 0 0 1 1 1 0 Ima1 N-terminal domain Lin-8 PF03353.15 CCH62866.1 - 6.1 6.3 6.0 12 5.4 6.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF5521 PF17659.1 CCH62866.1 - 9.4 3.9 9.2 14 3.3 9.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) AAA PF00004.29 CCH62867.1 - 1.4e-52 177.6 1.3 2.2e-38 131.7 0.0 3.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCH62867.1 - 1.1e-09 38.7 0.4 0.00027 21.2 0.1 3.8 2 2 1 3 3 2 2 AAA domain AAA_lid_3 PF17862.1 CCH62867.1 - 4.6e-09 35.9 0.0 8.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 CCH62867.1 - 3.8e-08 32.9 0.1 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 CCH62867.1 - 1.1e-07 32.4 0.1 0.027 14.8 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CCH62867.1 - 4.2e-07 30.0 0.0 0.0053 16.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CCH62867.1 - 6.9e-07 29.0 0.5 2.9e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 CCH62867.1 - 1.2e-06 28.7 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CCH62867.1 - 1.7e-06 28.3 0.0 0.0016 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CCH62867.1 - 5.6e-06 25.9 4.0 0.0024 17.3 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCH62867.1 - 1e-05 25.3 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CCH62867.1 - 1.1e-05 25.3 0.1 0.073 12.8 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 CCH62867.1 - 1.2e-05 25.4 0.1 0.063 13.3 0.0 3.1 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CCH62867.1 - 1.6e-05 25.3 0.0 0.16 12.4 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 CCH62867.1 - 2.1e-05 24.1 0.0 0.046 13.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCH62867.1 - 2.7e-05 24.0 0.0 0.084 12.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CCH62867.1 - 9.1e-05 22.3 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein PhoH PF02562.16 CCH62867.1 - 0.00011 21.7 0.0 0.29 10.5 0.0 2.7 3 0 0 3 3 2 2 PhoH-like protein ABC_tran PF00005.27 CCH62867.1 - 0.00017 22.1 0.3 0.068 13.7 0.1 2.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.12 CCH62867.1 - 0.00017 21.5 2.1 0.13 12.1 0.0 3.3 4 0 0 4 4 2 1 NACHT domain TsaE PF02367.17 CCH62867.1 - 0.00018 21.5 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 CCH62867.1 - 0.00023 21.7 1.3 0.49 11.0 0.0 3.4 4 0 0 4 4 2 2 AAA domain NB-ARC PF00931.22 CCH62867.1 - 0.00042 19.6 0.1 0.4 9.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase PF06745.13 CCH62867.1 - 0.00045 19.6 0.3 0.19 11.0 0.1 3.0 2 0 0 2 2 2 1 KaiC CDC48_N PF02359.18 CCH62867.1 - 0.0012 19.0 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TniB PF05621.11 CCH62867.1 - 0.0014 18.1 0.2 2.6 7.4 0.1 3.2 2 1 0 2 2 2 1 Bacterial TniB protein AAA_11 PF13086.6 CCH62867.1 - 0.0057 16.5 0.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CCH62867.1 - 0.0071 16.3 1.4 6.3 6.6 0.0 3.6 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CCH62867.1 - 0.0083 15.7 0.3 4 7.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 CCH62867.1 - 0.0091 15.9 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCH62867.1 - 0.01 15.6 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CCH62867.1 - 0.029 13.4 0.0 3.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.9 CCH62867.1 - 0.03 13.6 0.0 0.73 9.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 CCH62867.1 - 0.036 14.5 0.0 9.6 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCH62867.1 - 0.045 14.1 0.2 1.4 9.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CCH62867.1 - 0.046 13.3 0.2 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CCH62867.1 - 0.046 13.9 0.0 7.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCH62867.1 - 0.051 13.3 0.4 3 7.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.16 CCH62867.1 - 0.077 12.4 0.0 3.2 7.1 0.0 3.1 3 0 0 3 3 3 0 Isopentenyl transferase Cytidylate_kin PF02224.18 CCH62867.1 - 0.11 12.2 0.1 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Yos9_DD PF17880.1 CCH62869.1 - 1.7e-27 96.1 0.1 1.7e-27 96.1 0.1 3.7 3 1 0 3 3 3 1 Yos9 dimerzation domain PRKCSH PF07915.13 CCH62869.1 - 2.4e-11 44.5 0.3 2.4e-11 44.5 0.3 4.6 3 2 0 3 3 3 1 Glucosidase II beta subunit-like protein PROCT PF08084.11 CCH62869.1 - 0.03 14.3 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 PROCT (NUC072) domain Bromodomain PF00439.25 CCH62870.1 - 2e-14 53.4 2.3 3.5e-14 52.6 0.4 2.6 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 CCH62870.1 - 5.6e-05 23.1 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 CCH62870.1 - 0.0027 17.8 2.8 0.0027 17.8 2.8 3.8 4 0 0 4 4 4 1 Histone-fold protein TAFH PF07531.14 CCH62870.1 - 0.77 9.9 4.4 0.72 10.0 0.6 2.9 3 0 0 3 3 3 0 NHR1 homology to TAF UQ_con PF00179.26 CCH62871.1 - 3.9e-52 175.6 0.0 4.4e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCH62871.1 - 0.00099 19.4 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CCH62871.1 - 0.0045 16.7 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CCH62871.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain CBF PF03914.17 CCH62872.1 - 2.2e-50 171.0 0.2 2.2e-50 171.0 0.2 4.2 4 1 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 CCH62872.1 - 0.49 10.4 5.0 0.27 11.3 0.3 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TEA PF01285.18 CCH62873.1 - 8.5e-23 80.2 0.1 2.4e-22 78.8 0.1 1.8 1 0 0 1 1 1 1 TEA/ATTS domain FTHFS PF01268.19 CCH62874.1 - 8.3e-230 763.7 0.1 1.2e-229 763.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCH62874.1 - 5.9e-66 220.7 0.5 1.1e-65 219.8 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCH62874.1 - 2.8e-35 121.1 0.4 9.3e-35 119.4 0.4 2.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 CCH62874.1 - 0.014 15.5 1.6 0.16 12.0 1.1 2.7 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.20 CCH62874.1 - 0.053 13.6 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 CCH62874.1 - 0.16 11.3 1.0 1.2 8.4 0.5 2.3 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CbiA PF01656.23 CCH62874.1 - 0.23 11.5 1.6 9.2 6.3 0.1 3.8 4 1 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ribosomal_L19e PF01280.20 CCH62875.1 - 1.1e-58 197.4 8.8 1.1e-58 197.4 8.8 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.9 CCH62876.1 - 9.9e-17 60.9 0.4 9.9e-17 60.9 0.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) HSP20 PF00011.21 CCH62876.1 - 0.0033 17.6 0.4 0.0048 17.0 0.4 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family FokI_N PF02981.15 CCH62876.1 - 0.022 14.9 0.3 0.026 14.7 0.3 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain AAA_lid_7 PF17867.1 CCH62876.1 - 0.064 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain zinc_ribbon_15 PF17032.5 CCH62877.1 - 6.9e-07 29.9 2.3 7.6e-07 29.8 1.3 1.6 2 0 0 2 2 2 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 CCH62877.1 - 0.022 14.7 3.2 0.12 12.4 3.2 2.0 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RecR PF02132.15 CCH62877.1 - 0.12 11.9 2.2 2.1 8.0 0.2 2.3 2 0 0 2 2 2 0 RecR protein zf-LITAF-like PF10601.9 CCH62877.1 - 0.41 10.9 4.5 0.65 10.3 0.1 2.4 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain Msap1 PF17077.5 CCH62878.1 - 0.1 11.8 0.0 0.1 11.8 0.0 3.4 1 1 2 3 3 3 0 Mitotic spindle associated protein SHE1 Ala_racemase_N PF01168.20 CCH62880.1 - 9.1e-22 77.8 0.0 1.1e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 CCH62881.1 - 2.3e-65 221.2 32.8 2.7e-65 220.9 32.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CCH62881.1 - 0.051 13.8 0.0 0.24 11.6 0.0 2.2 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain Scm3 PF10384.9 CCH62881.1 - 0.23 11.2 2.1 19 5.1 0.1 3.3 3 0 0 3 3 3 0 Centromere protein Scm3 HMG_box PF00505.19 CCH62882.1 - 2e-25 89.0 0.5 3.2e-25 88.3 0.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCH62882.1 - 4.5e-19 68.8 0.6 6.7e-19 68.3 0.6 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 CCH62882.1 - 0.0035 17.9 0.5 0.012 16.2 0.0 1.8 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 CCH62882.1 - 0.016 15.2 2.7 0.021 14.8 2.4 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 CCH62882.1 - 0.022 14.7 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain RXT2_N PF08595.11 CCH62883.1 - 3.7e-28 98.5 4.9 3.7e-28 98.5 4.9 3.6 2 2 0 2 2 2 1 RXT2-like, N-terminal DUF3461 PF11944.8 CCH62883.1 - 0.018 15.1 0.9 0.055 13.6 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) MBOAT PF03062.19 CCH62884.1 - 2.1e-51 175.3 37.5 4.6e-51 174.2 37.5 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SWIB PF02201.18 CCH62885.1 - 0.00026 20.8 0.0 0.00073 19.4 0.0 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3270 PF11674.8 CCH62885.1 - 0.22 11.7 0.4 0.7 10.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) WD40 PF00400.32 CCH62886.1 - 1.8e-46 155.2 12.9 3e-08 34.2 0.1 12.8 13 0 0 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62886.1 - 4.8e-32 110.1 0.0 0.00079 19.7 0.0 9.6 4 2 7 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CCH62886.1 - 1.8e-23 82.8 0.0 3.3e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 CCH62886.1 - 9.4e-10 38.7 3.2 0.0013 18.7 0.0 5.7 3 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCH62886.1 - 2.5e-08 33.3 3.9 0.032 13.2 0.0 6.7 4 3 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCH62886.1 - 2.6e-07 29.7 7.1 0.26 9.9 0.0 5.9 3 2 1 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 CCH62886.1 - 0.00022 20.7 3.5 0.61 9.4 0.5 4.5 4 2 2 6 6 6 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 CCH62886.1 - 0.00024 20.9 3.9 0.095 12.7 0.2 4.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 CCH62886.1 - 0.0077 16.2 0.1 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CCH62886.1 - 0.0078 14.8 0.4 0.26 9.8 0.0 3.1 3 1 0 3 3 3 1 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 CCH62886.1 - 0.015 14.6 0.1 0.11 11.7 0.0 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 CCH62886.1 - 0.025 14.2 1.6 0.17 11.5 0.3 2.7 2 1 0 2 2 2 0 PQQ-like domain PALB2_WD40 PF16756.5 CCH62886.1 - 0.026 13.5 0.1 4 6.3 0.0 2.5 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain MPP6 PF10175.9 CCH62887.1 - 2.4e-22 79.9 10.9 2.8e-22 79.6 10.9 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 UPF0029 PF01205.19 CCH62888.1 - 8.5e-30 103.2 0.0 1.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CCH62888.1 - 3.4e-07 30.5 0.7 1.6e-06 28.4 0.7 2.0 1 1 0 1 1 1 1 RWD domain TPR_1 PF00515.28 CCH62889.1 - 2.8e-14 52.2 0.0 2.8e-06 26.9 0.0 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62889.1 - 6.2e-12 44.7 0.0 3.6e-05 23.5 0.0 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCH62889.1 - 9.7e-11 41.0 0.4 3.1e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCH62889.1 - 2.1e-09 36.9 0.0 1.7e-08 34.0 0.0 2.2 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.6 CCH62889.1 - 1e-05 25.7 0.0 0.017 15.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCH62889.1 - 1.4e-05 25.1 0.0 4.7e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCH62889.1 - 2.5e-05 24.7 0.0 4.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCH62889.1 - 6.1e-05 23.5 0.0 0.6 11.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCH62889.1 - 0.00044 20.1 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCH62889.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CCH62889.1 - 0.016 14.7 0.0 0.89 9.1 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_16 PF13432.6 CCH62889.1 - 0.017 15.8 0.0 1.7 9.4 0.0 2.2 1 1 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 CCH62889.1 - 0.017 14.6 0.3 0.47 9.9 0.1 2.1 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like SRP_TPR_like PF17004.5 CCH62889.1 - 0.018 15.1 0.1 0.033 14.2 0.1 1.5 1 1 1 2 2 2 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 CCH62889.1 - 0.023 14.8 0.0 0.84 9.8 0.0 2.4 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 CCH62889.1 - 0.03 14.4 0.5 6.7 6.9 0.0 2.5 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain U3_assoc_6 PF08640.11 CCH62889.1 - 0.041 14.0 0.3 0.062 13.4 0.3 1.3 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 DUF5398 PF17376.2 CCH62889.1 - 0.079 13.6 0.1 0.12 13.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5398) PH PF00169.29 CCH62890.1 - 6.7e-11 42.6 2.5 5e-10 39.8 0.3 3.0 2 0 0 2 2 2 1 PH domain VASt PF16016.5 CCH62890.1 - 1.2e-07 32.2 0.5 3.2e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CCH62890.1 - 1.8e-07 31.1 8.9 5.8e-07 29.5 8.9 1.9 1 0 0 1 1 1 1 BAR domain of APPL family ANTH PF07651.16 CCH62891.1 - 7.8e-57 192.4 0.1 1.2e-56 191.8 0.1 1.3 1 0 0 1 1 1 1 ANTH domain MPS2 PF17060.5 CCH62891.1 - 0.00017 21.0 0.7 0.0003 20.2 0.7 1.3 1 0 0 1 1 1 1 Monopolar spindle protein 2 Atg14 PF10186.9 CCH62891.1 - 0.0052 15.9 0.2 0.0087 15.2 0.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CCH62891.1 - 0.0076 15.2 2.1 0.013 14.4 2.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein ENTH PF01417.20 CCH62891.1 - 0.014 15.4 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 ENTH domain DUF3417 PF11897.8 CCH62891.1 - 0.057 13.9 0.6 20 5.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) DUF641 PF04859.12 CCH62891.1 - 0.061 13.7 0.8 0.13 12.6 0.8 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.15 CCH62891.1 - 0.077 12.5 0.8 0.12 11.9 0.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 CCH62891.1 - 0.14 11.6 4.1 0.24 10.8 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF745 PF05335.13 CCH62891.1 - 0.24 11.1 0.1 0.45 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TFIIA PF03153.13 CCH62891.1 - 0.29 11.1 15.6 0.015 15.4 8.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAM76 PF16046.5 CCH62891.1 - 0.5 9.7 1.1 0.79 9.0 1.1 1.3 1 0 0 1 1 1 0 FAM76 protein ATG16 PF08614.11 CCH62891.1 - 1.2 9.3 10.1 3.7 7.7 9.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) G10 PF01125.17 CCH62892.1 - 1.6e-61 206.4 6.8 1.8e-61 206.2 6.8 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 CCH62893.1 - 1.1e-33 115.4 0.1 1.1e-33 115.4 0.1 2.3 2 0 0 2 2 2 1 Forkhead domain SDA1 PF05285.12 CCH62893.1 - 0.75 9.2 25.3 0.098 12.1 21.2 1.5 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CCH62893.1 - 1.3 7.1 21.3 2.2 6.4 21.3 1.3 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4_2 PF13923.6 CCH62894.1 - 1e-11 44.5 10.4 1e-11 44.5 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCH62894.1 - 1.9e-10 40.4 10.3 1.9e-10 40.4 10.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCH62894.1 - 2.5e-08 33.6 9.3 1.5e-07 31.2 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH62894.1 - 3.9e-08 33.2 17.5 9.3e-08 32.0 10.5 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCH62894.1 - 1.7e-06 28.0 9.8 1.7e-06 28.0 9.8 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CCH62894.1 - 3.2e-06 27.4 14.5 4.6e-06 26.9 9.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CCH62894.1 - 4.6e-06 26.5 13.4 6e-06 26.1 8.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCH62894.1 - 5.1e-06 26.2 13.0 3.6e-05 23.5 7.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SAP PF02037.27 CCH62894.1 - 6.1e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_6 PF14835.6 CCH62894.1 - 2.8e-05 23.9 4.7 2.8e-05 23.9 4.7 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CCH62894.1 - 0.00038 20.7 4.4 0.00038 20.7 4.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CCH62894.1 - 0.001 19.1 7.3 0.0026 17.9 7.3 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 CCH62894.1 - 0.011 15.9 0.2 0.077 13.2 0.0 2.5 3 0 0 3 3 3 0 U-box domain zf-RING_4 PF14570.6 CCH62894.1 - 0.63 9.9 6.4 0.7 9.7 2.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Phos_pyr_kin PF08543.12 CCH62895.1 - 9.5e-10 38.3 0.0 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCH62895.1 - 0.052 12.9 0.1 0.26 10.5 0.0 2.1 1 1 1 2 2 2 0 pfkB family carbohydrate kinase Lipase_3 PF01764.25 CCH62896.1 - 5.9e-10 39.2 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CCH62896.1 - 0.016 15.8 0.0 0.027 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CCH62896.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 CCH62896.1 - 0.079 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pro_isomerase PF00160.21 CCH62897.1 - 1.9e-17 64.0 0.1 2.9e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 CCH62898.1 - 6.9e-64 215.8 0.0 2.4e-63 214.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH62898.1 - 2.5e-37 128.5 0.2 1.4e-26 93.3 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCH62898.1 - 0.00037 19.9 0.3 0.0041 16.5 0.0 2.6 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 CCH62898.1 - 0.061 12.9 0.0 0.45 10.1 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCH62898.1 - 0.12 11.2 0.0 0.12 11.2 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 CCH62898.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.28 CCH62899.1 - 1.3e-35 123.7 0.9 2e-35 123.1 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Chorismate_bind PF00425.18 CCH62900.1 - 4.5e-64 216.5 0.0 6.9e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CCH62900.1 - 4.2e-30 104.9 0.0 7.1e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CCH62900.1 - 1.9e-19 70.3 0.1 5.9e-19 68.7 0.1 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CCH62900.1 - 1.3e-08 34.9 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Orthopox_F6 PF06601.12 CCH62900.1 - 0.13 12.4 3.2 0.8 9.9 0.9 3.2 2 0 0 2 2 2 0 Orthopoxvirus F6 protein Glucosamine_iso PF01182.20 CCH62901.1 - 1.2e-53 182.3 0.0 2.2e-53 181.4 0.0 1.4 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PQ-loop PF04193.14 CCH62902.1 - 4.3e-20 71.2 11.9 8.7e-13 47.8 0.3 3.6 3 1 1 4 4 4 2 PQ loop repeat COX14 PF14880.6 CCH62902.1 - 0.025 14.4 0.1 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly LMBR1 PF04791.16 CCH62903.1 - 3.1e-25 89.1 35.2 5.2e-25 88.3 35.2 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Orthopox_A49R PF06489.11 CCH62903.1 - 0.013 15.8 1.9 0.013 15.8 1.9 2.2 2 1 0 2 2 2 0 Orthopoxvirus A49R protein SPC25 PF06703.11 CCH62903.1 - 0.37 10.5 4.3 6.9 6.4 0.4 2.8 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3341 PF11821.8 CCH62903.1 - 0.85 9.2 3.6 0.73 9.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Cyt_bd_oxida_II PF02322.15 CCH62903.1 - 2.2 7.6 12.6 0.25 10.7 0.2 3.0 3 0 0 3 3 3 0 Cytochrome bd terminal oxidase subunit II PI31_Prot_C PF08577.11 CCH62904.1 - 5.1e-10 40.4 4.5 5.1e-10 40.4 4.5 2.4 3 0 0 3 3 3 1 PI31 proteasome regulator PP2C PF00481.21 CCH62905.1 - 3.3e-27 95.7 0.0 7.3e-26 91.3 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CCH62905.1 - 0.025 14.2 0.0 0.073 12.7 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C LRR_4 PF12799.7 CCH62907.1 - 2.3e-06 27.8 13.0 0.25 11.8 0.3 7.8 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) F-box PF00646.33 CCH62907.1 - 0.00028 20.7 0.2 0.00077 19.3 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CCH62907.1 - 0.00053 19.8 0.1 0.0015 18.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 CCH62907.1 - 1.3 9.8 6.5 1.2e+02 3.9 0.8 6.4 5 1 0 5 5 5 0 Leucine Rich Repeat PUF PF00806.19 CCH62908.1 - 5.4e-30 101.4 0.7 9.7e-05 21.9 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CCH62908.1 - 3.1e-06 26.9 0.0 1.1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.29 CCH62909.1 - 0.11 13.0 1.5 0.43 11.1 0.0 3.0 3 0 0 3 3 3 0 PH domain Ribosomal_L37ae PF01780.19 CCH62910.1 - 9e-41 137.9 9.1 1e-40 137.7 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CCH62910.1 - 0.00056 20.0 2.7 0.00076 19.6 2.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1364 PF07102.12 CCH62910.1 - 0.0016 18.2 0.7 0.0024 17.7 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) zf-H2C2_2 PF13465.6 CCH62910.1 - 0.0019 18.6 0.7 0.45 11.0 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 CCH62910.1 - 0.0035 17.3 3.5 0.0062 16.5 3.5 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Rep_fac-A_C PF08646.10 CCH62910.1 - 0.0062 16.3 0.4 0.007 16.1 0.4 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain CarbpepA_inh PF02977.15 CCH62910.1 - 0.0063 16.3 0.6 0.0063 16.3 0.6 2.0 1 1 1 2 2 2 1 Carboxypeptidase A inhibitor zf-ribbon_3 PF13248.6 CCH62910.1 - 0.022 14.2 1.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain C1_2 PF03107.16 CCH62910.1 - 0.028 14.7 1.9 0.26 11.6 2.0 2.0 1 1 1 2 2 2 0 C1 domain Sgf11 PF08209.11 CCH62910.1 - 0.039 13.5 0.4 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF1451 PF07295.11 CCH62910.1 - 0.047 13.7 0.4 0.067 13.2 0.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ima1_N PF09779.9 CCH62910.1 - 0.05 14.5 0.2 0.064 14.1 0.2 1.3 1 0 0 1 1 1 0 Ima1 N-terminal domain zf_UBZ PF18439.1 CCH62910.1 - 0.073 12.7 0.7 8.3 6.1 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2175 PF09943.9 CCH62910.1 - 0.074 13.3 0.6 2.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zinc_ribbon_10 PF10058.9 CCH62910.1 - 0.075 12.8 0.8 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C4_ClpX PF06689.13 CCH62910.1 - 0.13 12.1 3.4 0.25 11.2 0.4 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger A2L_zn_ribbon PF08792.10 CCH62910.1 - 0.15 11.8 2.5 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Sec23_Sec24 PF04810.15 CCH62910.1 - 0.16 12.0 4.0 2.2 8.4 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-BED PF02892.15 CCH62910.1 - 0.53 10.4 5.5 2.4 8.2 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger Zn_clus PF00172.18 CCH62911.1 - 1e-07 31.9 10.4 1.7e-07 31.2 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Svf1 PF08622.10 CCH62912.1 - 1.9e-40 138.6 0.4 3.2e-40 137.9 0.4 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CCH62912.1 - 1.6e-39 135.4 1.0 7.9e-39 133.1 1.0 2.1 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Utp13 PF08625.11 CCH62913.1 - 2.1e-47 160.6 0.1 3.6e-47 159.8 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CCH62913.1 - 4.9e-42 141.1 23.9 1.9e-06 28.5 0.0 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62913.1 - 1.4e-19 70.2 1.1 0.00055 20.2 0.0 6.5 5 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCH62913.1 - 3.8e-08 33.0 10.5 0.0004 19.8 0.2 4.2 3 2 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 CCH62913.1 - 9.1e-05 21.3 4.8 0.37 9.4 0.1 5.1 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCH62913.1 - 0.0069 15.4 12.1 6 5.7 0.4 6.5 3 2 4 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CCH62913.1 - 0.11 12.5 0.0 0.85 9.6 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Rsa3 PF14615.6 CCH62914.1 - 1.3e-17 63.0 0.1 2.4e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 VIT1 PF01988.19 CCH62915.1 - 4.1e-60 203.3 0.1 5.1e-60 203.0 0.1 1.1 1 0 0 1 1 1 1 VIT family ABC2_membrane_5 PF13346.6 CCH62915.1 - 0.025 14.1 1.9 0.043 13.4 1.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein T3RM_EcoP15I_C PF18273.1 CCH62915.1 - 0.043 14.1 0.3 0.079 13.3 0.3 1.4 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain Histone PF00125.24 CCH62916.1 - 2e-19 70.2 3.1 2.5e-19 69.9 3.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCH62916.1 - 7.7e-06 26.1 0.1 1.4e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCH62916.1 - 0.0015 19.0 0.0 0.0026 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CCH62916.1 - 0.015 15.4 0.6 0.016 15.2 0.6 1.1 1 0 0 1 1 1 0 YscO-like protein CENP-W PF15510.6 CCH62916.1 - 0.037 14.2 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein Histone_H2A_C PF16211.5 CCH62917.1 - 4.2e-21 74.4 1.8 6.9e-21 73.7 1.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCH62917.1 - 6.6e-18 65.3 0.0 9.3e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCH62917.1 - 8.9e-06 25.9 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Orthopox_C10L PF07020.11 CCH62918.1 - 0.0032 18.2 0.0 0.013 16.3 0.0 2.1 1 1 0 1 1 1 1 Orthopoxvirus C10L protein sCache_like PF16736.5 CCH62918.1 - 6.1 7.0 19.8 0.039 14.1 1.5 4.8 3 1 1 4 4 4 0 Single Cache-like ADK PF00406.22 CCH62919.1 - 4.5e-60 202.1 0.0 5.3e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCH62919.1 - 6.7e-23 81.6 0.1 1.7e-22 80.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 CCH62919.1 - 4.9e-17 61.6 0.0 9.4e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CCH62919.1 - 1.3e-05 25.4 0.0 2.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCH62919.1 - 5.9e-05 23.6 0.0 0.0002 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CCH62919.1 - 0.063 13.0 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase CFIA_Pcf11 PF11526.8 CCH62920.1 - 1.2e-17 64.1 28.2 1.2e-17 64.1 28.2 3.9 3 1 0 3 3 3 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 CCH62920.1 - 0.015 16.1 0.7 0.13 13.2 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase II-binding domain. Roughex PF06020.11 CCH62920.1 - 0.11 11.5 7.0 0.12 11.5 5.6 1.7 2 0 0 2 2 2 0 Drosophila roughex protein zf-C2H2_4 PF13894.6 CCH62920.1 - 0.32 12.0 3.7 2 9.5 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger MalF_P2 PF14785.6 CCH62921.1 - 0.019 15.0 1.9 0.019 15.0 1.9 2.1 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain RNase_E_G PF10150.9 CCH62921.1 - 0.022 14.2 4.0 0.052 13.0 4.0 1.8 1 0 0 1 1 1 0 Ribonuclease E/G family DUF3767 PF12597.8 CCH62922.1 - 3.5e-36 123.0 0.0 4.8e-36 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) 60KD_IMP PF02096.20 CCH62923.1 - 8.5e-11 42.0 2.7 1.7e-09 37.8 2.7 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.13 CCH62924.1 - 3.3e-27 94.4 0.3 3.8e-27 94.2 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf_Rg PF17915.1 CCH62924.1 - 0.028 13.8 0.4 0.056 12.9 0.4 1.5 1 0 0 1 1 1 0 Reverse gyrase zinc finger MFS_1 PF07690.16 CCH62925.1 - 3.6e-18 65.6 23.5 3.6e-18 65.6 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 CCH62925.1 - 0.071 12.9 0.5 0.2 11.5 0.5 1.8 1 0 0 1 1 1 0 Bacteriophage holin family HP1 zf-C2H2 PF00096.26 CCH62926.1 - 8.2e-07 29.1 14.3 0.00011 22.5 1.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH62926.1 - 0.00022 21.5 14.3 0.00026 21.3 3.0 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH62926.1 - 0.0014 19.3 13.5 0.012 16.3 1.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH62926.1 - 0.21 11.9 5.6 2 8.8 1.7 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCH62926.1 - 8.7 6.9 6.1 72 4.0 1.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Arrestin_C PF02752.22 CCH62927.1 - 1.6e-11 44.8 0.2 2.1e-09 38.0 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCH62927.1 - 0.0003 20.9 0.3 0.0027 17.8 0.3 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain FSA_C PF10479.9 CCH62927.1 - 0.13 10.4 1.9 0.2 9.8 1.9 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HSP70 PF00012.20 CCH62929.1 - 1.2e-207 690.8 8.7 1.5e-207 690.5 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCH62929.1 - 6e-19 68.0 0.9 4.7e-16 58.5 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCH62929.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CCH62929.1 - 0.0069 15.9 0.1 0.32 10.4 0.0 2.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family P21-Arc PF04062.14 CCH62930.1 - 7.5e-73 244.2 0.1 8.4e-73 244.1 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit RSB_motif PF16294.5 CCH62930.1 - 0.14 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif CNH PF00780.22 CCH62931.1 - 4e-75 253.0 0.6 8.8e-75 251.8 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 CCH62931.1 - 6.3e-37 126.7 0.0 6.3e-37 126.7 0.0 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain RhoGEF PF00621.20 CCH62931.1 - 9.3e-30 104.2 0.0 2.2e-29 103.0 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 CCH62931.1 - 7.4e-14 51.6 0.0 1.6e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CdiA_C_tRNase PF18664.1 CCH62931.1 - 0.17 12.1 2.2 16 5.7 0.4 3.4 3 0 0 3 3 3 0 CdiA C-terminal tRNase domain ELO PF01151.18 CCH62932.1 - 1.2e-60 205.2 30.6 1.5e-60 204.8 30.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family OAD_gamma PF04277.13 CCH62932.1 - 0.015 15.9 0.3 0.062 13.9 0.3 2.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-C2H2_4 PF13894.6 CCH62933.1 - 5.1e-08 33.1 19.8 0.0017 19.1 1.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCH62933.1 - 5.5e-05 23.0 0.4 5.5e-05 23.0 0.4 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH62933.1 - 0.0014 19.0 2.5 0.0014 19.0 2.5 5.5 5 0 0 5 5 5 1 Zinc finger, C2H2 type DUF2242 PF10001.9 CCH62933.1 - 0.051 13.7 0.3 0.15 12.2 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) zf-C2H2_jaz PF12171.8 CCH62933.1 - 0.059 13.7 4.5 0.081 13.2 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CCH62933.1 - 0.31 11.4 5.8 0.12 12.6 0.8 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 CCH62933.1 - 0.34 10.8 11.8 2.9 7.9 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.7 CCH62933.1 - 4.1 7.9 7.4 0.3 11.6 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type KRE9 PF05390.11 CCH62934.1 - 6.4e-28 97.5 0.3 4.1e-15 56.4 0.0 2.4 1 1 1 2 2 2 2 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCH62934.1 - 1.6e-06 28.8 0.5 4.4e-06 27.4 0.5 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family La PF05383.17 CCH62935.1 - 4.8e-22 77.8 0.1 1.5e-21 76.2 0.0 1.9 2 0 0 2 2 2 1 La domain SprB PF13573.6 CCH62935.1 - 0.13 12.1 2.3 0.27 11.0 2.3 1.6 1 0 0 1 1 1 0 SprB repeat K_channel_TID PF07941.11 CCH62936.1 - 1.2 9.7 7.4 1.4 9.5 6.1 1.9 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.16 CCH62937.1 - 6.5e-19 68.1 18.3 8.6e-19 67.7 18.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Imm17 PF15562.6 CCH62937.1 - 0.012 15.4 1.5 0.066 13.1 1.5 2.4 1 1 0 1 1 1 0 Immunity protein 17 SecY PF00344.20 CCH62938.1 - 2.1e-60 204.6 12.5 2.6e-60 204.2 12.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCH62938.1 - 3.1e-17 62.1 1.6 6.8e-17 61.0 0.1 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p DUF2975 PF11188.8 CCH62938.1 - 8.5 6.3 12.7 0.11 12.3 1.7 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2975) ADH_zinc_N PF00107.26 CCH62939.1 - 1.2e-11 44.6 0.1 6.5e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCH62939.1 - 0.00045 20.1 0.3 0.0011 18.8 0.2 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.7 CCH62940.1 - 1.7e-07 31.7 0.0 0.033 14.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 CCH62940.1 - 1.9e-07 30.9 3.4 1.5e-06 28.0 0.1 3.5 2 1 0 2 2 2 1 KilA-N domain Ank_5 PF13857.6 CCH62940.1 - 4.7e-05 23.6 0.1 0.082 13.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH62940.1 - 5.7e-05 23.6 0.1 0.36 11.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CCH62940.1 - 0.00073 19.9 0.1 0.52 10.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CCH62940.1 - 0.0045 17.4 0.2 12 6.8 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Y_phosphatase3 PF13350.6 CCH62941.1 - 7.1e-52 176.7 0.0 1.1e-51 176.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 CCH62941.1 - 8.6e-08 31.7 0.0 7.2e-07 28.7 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCH62941.1 - 2.7e-05 23.9 0.8 0.082 12.5 0.3 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCH62941.1 - 0.00021 22.0 0.0 0.00031 21.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase2 PF03162.13 CCH62941.1 - 0.00042 19.9 0.0 0.0014 18.3 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Chlorophyllase2 PF12740.7 CCH62941.1 - 0.0099 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.11 CCH62941.1 - 0.011 15.1 0.2 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Y_phosphatase PF00102.27 CCH62941.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_S9 PF00326.21 CCH62941.1 - 0.076 12.5 0.0 1 8.8 0.0 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family CRAL_TRIO PF00650.20 CCH62942.1 - 2.4e-42 144.4 0.1 4.9e-42 143.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CCH62942.1 - 8e-11 42.3 0.2 1.3e-10 41.6 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCH62942.1 - 0.0013 18.8 3.2 0.0015 18.6 0.5 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain RAM PF15320.6 CCH62942.1 - 1.9 9.2 3.7 3.7 8.2 0.0 2.4 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Macoilin PF09726.9 CCH62942.1 - 1.9 6.9 11.0 3.3 6.1 11.0 1.3 1 0 0 1 1 1 0 Macoilin family tRNA-synt_1 PF00133.22 CCH62944.1 - 1.7e-50 171.9 1.0 1.1e-15 57.0 0.5 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CCH62944.1 - 4.9e-39 133.8 0.0 9.2e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CCH62944.1 - 5.7e-29 101.1 1.0 1.7e-20 73.2 0.0 5.1 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCH62944.1 - 8e-08 32.4 0.7 8e-08 32.4 0.7 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCH62944.1 - 0.00029 20.3 0.0 0.22 10.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 CCH62944.1 - 0.002 17.1 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) SMC_N PF02463.19 CCH62945.1 - 2.6e-14 53.2 0.5 2.6e-14 53.2 0.5 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCH62945.1 - 2.2e-09 38.1 39.8 2.2e-09 38.1 39.8 6.5 2 1 1 4 4 3 1 AAA domain AAA_15 PF13175.6 CCH62945.1 - 1.3e-08 34.9 35.7 1.3e-08 34.9 35.7 4.1 2 2 0 2 2 1 1 AAA ATPase domain AAA_29 PF13555.6 CCH62945.1 - 0.00028 20.5 0.1 0.00072 19.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 CCH62945.1 - 0.00039 20.7 0.0 0.0032 17.8 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCH62945.1 - 0.00098 19.0 1.2 0.00098 19.0 1.2 4.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system COG5 PF10392.9 CCH62945.1 - 0.0018 18.5 2.6 0.0018 18.5 2.6 4.4 4 1 0 4 4 4 1 Golgi transport complex subunit 5 Spc7 PF08317.11 CCH62945.1 - 0.0027 16.7 78.3 0.0047 15.9 14.8 4.6 2 2 2 4 4 4 3 Spc7 kinetochore protein Ploopntkinase3 PF18751.1 CCH62945.1 - 0.073 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 CCH62945.1 - 0.08 13.5 0.1 0.08 13.5 0.1 5.7 4 2 0 4 4 1 0 ABC transporter AAA_27 PF13514.6 CCH62945.1 - 0.21 11.2 0.1 0.21 11.2 0.1 4.5 4 1 0 4 4 4 0 AAA domain Cytochrom_C_2 PF01322.20 CCH62945.1 - 0.28 12.1 0.1 0.28 12.1 0.1 4.0 2 2 1 4 4 4 0 Cytochrome C' UPF0227 PF05728.12 CCH62945.1 - 0.62 10.0 6.9 0.38 10.7 0.6 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Baculo_PEP_C PF04513.12 CCH62945.1 - 0.76 9.8 44.9 3.1 7.9 10.0 5.9 2 2 5 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 CCH62945.1 - 2.1 5.7 66.8 2.7 5.4 28.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) HrpB7 PF09486.10 CCH62945.1 - 2.3 8.6 32.3 0.91 9.9 5.4 5.3 2 2 3 5 5 5 0 Bacterial type III secretion protein (HrpB7) DUF4094 PF13334.6 CCH62945.1 - 2.9 8.4 18.0 0.47 10.9 3.8 4.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Fib_alpha PF08702.10 CCH62945.1 - 4.7 7.4 75.4 0.036 14.3 8.2 6.1 3 2 2 5 5 5 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CCH62945.1 - 6 7.3 66.4 3.3 8.1 14.9 4.5 2 2 3 5 5 5 0 Fez1 Uso1_p115_head PF04869.14 CCH62946.1 - 1.7e-87 293.5 2.1 2.3e-56 191.2 0.3 3.5 3 0 0 3 3 3 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CCH62946.1 - 2.9e-15 56.7 28.9 2.9e-15 56.7 28.9 13.3 2 1 8 11 11 11 2 Uso1 / p115 like vesicle tethering protein, C terminal region ATG16 PF08614.11 CCH62946.1 - 0.0024 18.1 25.4 0.0024 18.1 25.4 10.3 2 2 7 9 9 9 3 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CCH62946.1 - 0.0028 17.7 24.6 0.0028 17.7 24.6 11.7 1 1 12 14 14 14 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Arm_vescicular PF18770.1 CCH62946.1 - 0.019 14.9 0.0 0.067 13.1 0.0 2.0 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Rad52_Rad22 PF04098.15 CCH62947.1 - 3.1e-28 98.6 0.3 3.9e-28 98.3 0.3 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.12 CCH62948.1 - 0 1109.7 8.8 0 1109.2 8.8 1.3 1 0 0 1 1 1 1 IKI3 family Methyltransf_31 PF13847.6 CCH62948.1 - 0.1 12.4 0.1 0.44 10.3 0.1 2.1 1 0 0 1 1 1 0 Methyltransferase domain MIT PF04212.18 CCH62948.1 - 6.3 6.9 10.3 21 5.3 0.0 4.3 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 CCH62948.1 - 9.1 6.8 10.5 7.9 7.0 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.21 CCH62949.1 - 1.5e-15 56.7 4.3 1.6e-15 56.6 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.12 CCH62949.1 - 0.039 14.2 1.8 2.3 8.6 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Peptidase_M16_M PF16187.5 CCH62950.1 - 9e-82 274.5 6.5 9e-82 274.5 6.5 2.4 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CCH62950.1 - 5.4e-38 130.3 0.0 4.4e-37 127.4 0.0 2.6 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCH62950.1 - 1.7e-31 109.7 4.9 2e-16 60.6 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Phage_connect_1 PF05135.13 CCH62951.1 - 0.0074 16.8 1.2 0.031 14.8 0.3 2.5 2 0 0 2 2 2 1 Phage gp6-like head-tail connector protein APG5 PF04106.12 CCH62951.1 - 0.041 13.5 1.2 0.1 12.2 1.1 1.8 1 1 0 1 1 1 0 Autophagy protein Apg5 SBDS_C PF09377.10 CCH62951.1 - 0.61 10.1 4.6 1.8 8.6 3.7 2.3 2 1 0 2 2 2 0 SBDS protein C-terminal domain Bromo_TP_like PF17027.5 CCH62951.1 - 4.7 7.4 15.7 0.15 12.2 5.2 3.5 4 0 0 4 4 4 0 Histone-fold protein UQ_con PF00179.26 CCH62952.1 - 2.3e-43 147.2 0.1 2.6e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCH62952.1 - 3.5e-05 23.5 0.0 4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CCH62952.1 - 0.16 12.3 1.3 0.24 11.7 1.3 1.6 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 CCH62953.1 - 2.5e-56 191.2 20.1 3.3e-56 190.8 20.1 1.2 1 0 0 1 1 1 1 Pex19 protein family Helo_like_N PF17111.5 CCH62953.1 - 2.1 7.7 6.2 0.44 9.9 0.9 2.3 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins DUF2408 PF10303.9 CCH62953.1 - 3.5 8.2 17.8 0.18 12.4 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) MSC PF09402.10 CCH62953.1 - 3.8 6.9 9.0 0.63 9.4 5.0 1.6 1 1 0 2 2 2 0 Man1-Src1p-C-terminal domain CFEM PF05730.11 CCH62954.1 - 1.2e-09 38.1 14.0 2.5e-09 37.1 14.0 1.5 1 0 0 1 1 1 1 CFEM domain Sec10 PF07393.11 CCH62954.1 - 2.6 6.4 7.7 3.1 6.1 7.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Macoilin PF09726.9 CCH62954.1 - 6.5 5.2 21.0 7.6 4.9 21.0 1.1 1 0 0 1 1 1 0 Macoilin family zf-RING_5 PF14634.6 CCH62955.1 - 2.7e-07 30.4 8.5 4.8e-07 29.6 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 CCH62955.1 - 0.36 11.0 4.4 0.17 12.1 1.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 CCH62955.1 - 0.94 9.4 5.3 2.4 8.1 5.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CCH62955.1 - 1.1 9.6 6.8 2.2 8.7 6.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 CCH62955.1 - 2.3 8.1 6.7 5.1 7.0 6.7 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH62955.1 - 2.9 8.0 6.4 6.8 6.8 6.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Sec1 PF00995.23 CCH62956.1 - 2e-84 284.9 25.7 2.3e-84 284.7 25.7 1.0 1 0 0 1 1 1 1 Sec1 family Lzipper-MIP1 PF14389.6 CCH62958.1 - 0.00034 20.9 3.5 0.00065 19.9 3.5 1.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Swi5 PF07061.11 CCH62958.1 - 6.4 6.9 12.2 36 4.5 9.2 2.9 2 1 0 2 2 2 0 Swi5 Dus PF01207.17 CCH62959.1 - 2.4e-42 145.1 0.0 2.2e-32 112.4 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CCH62959.1 - 5.7 7.0 9.1 0.39 10.7 3.5 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_aberr PF17017.5 CCH62960.1 - 6.4e-06 26.4 6.0 0.0039 17.4 0.2 3.2 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CCH62960.1 - 0.00012 22.6 12.7 0.046 14.6 0.6 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCH62960.1 - 0.00015 22.0 15.6 0.017 15.6 0.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCH62960.1 - 0.00045 20.4 0.6 1.6 9.1 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCH62960.1 - 0.03 14.7 1.5 2.7 8.5 0.1 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CCH62960.1 - 0.11 13.0 17.9 0.14 12.6 1.2 4.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CCH62960.1 - 2.7 8.1 9.2 3 7.9 1.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger CoiA PF06054.11 CCH62961.1 - 0.0035 16.6 1.4 0.0046 16.2 1.4 1.2 1 0 0 1 1 1 1 Competence protein CoiA-like family DUF1765 PF08578.10 CCH62962.1 - 4.3e-11 43.3 6.9 4.3e-11 43.3 6.9 4.1 3 1 2 5 5 5 1 Protein of unknown function (DUF1765) PMT PF02366.18 CCH62962.1 - 0.076 12.6 2.0 0.14 11.7 2.0 1.4 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4050 PF13259.6 CCH62963.1 - 1.3e-09 38.7 20.2 2e-09 38.1 0.1 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) His_Phos_2 PF00328.22 CCH62964.1 - 3.2e-131 438.2 1.6 4.5e-131 437.7 1.6 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CCH62964.1 - 1.4e-37 127.7 0.1 4e-37 126.3 0.1 1.9 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CCH62964.1 - 2e-05 24.3 0.1 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CCH62964.1 - 0.028 14.5 0.2 0.15 12.1 0.0 2.2 3 0 0 3 3 3 0 ATP-grasp domain MFS_1_like PF12832.7 CCH62965.1 - 0.0056 15.6 0.7 0.0059 15.5 0.7 1.1 1 0 0 1 1 1 1 MFS_1 like family Pribosyltran_N PF13793.6 CCH62966.1 - 6.1e-40 135.8 0.0 1.5e-39 134.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCH62966.1 - 7.3e-40 137.0 2.2 1.3e-31 110.1 0.2 2.2 1 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCH62966.1 - 7.6e-06 25.5 0.1 0.0042 16.6 0.0 2.5 2 1 0 2 2 2 2 Phosphoribosyl transferase domain DUF1729 PF08354.10 CCH62967.1 - 5.3e-151 502.5 0.0 7.9e-151 501.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CCH62967.1 - 4.3e-101 338.6 0.0 1.1e-100 337.3 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain FAS_N PF17828.1 CCH62967.1 - 6.1e-44 149.1 2.2 1.6e-43 147.8 2.2 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta FAS_meander PF17951.1 CCH62967.1 - 9.8e-36 122.8 0.9 7.4e-35 119.9 0.9 2.4 1 1 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 CCH62967.1 - 7.4e-35 119.2 0.1 1.8e-34 118.0 0.1 1.7 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 CCH62967.1 - 4.5e-34 118.2 0.0 1.1e-33 117.0 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 CCH62967.1 - 4.7e-14 52.7 0.0 1.5e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.15 CCH62967.1 - 0.19 11.1 0.1 1.5 8.1 0.1 2.3 1 1 0 1 1 1 0 Nitronate monooxygenase Mtr2 PF10429.9 CCH62968.1 - 8.7e-64 214.4 0.8 1e-63 214.2 0.8 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Mo25 PF08569.11 CCH62969.1 - 1.2e-103 347.0 24.8 1.4e-103 346.8 24.8 1.0 1 0 0 1 1 1 1 Mo25-like CDC73_C PF05179.14 CCH62970.1 - 2.1e-53 180.2 3.4 4.2e-53 179.2 3.4 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal EF-hand_1 PF00036.32 CCH62971.1 - 7.7e-26 87.7 13.5 5e-06 25.7 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCH62971.1 - 9.2e-23 80.5 15.6 3.2e-13 49.9 2.4 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CCH62971.1 - 1.8e-20 71.1 6.5 0.00024 20.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CCH62971.1 - 1.8e-16 58.8 13.5 0.00087 18.7 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CCH62971.1 - 6.2e-12 45.2 14.3 0.01 15.6 0.2 4.4 4 1 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CCH62971.1 - 4.4e-07 30.2 0.2 0.044 14.1 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CCH62971.1 - 8.7e-07 28.8 11.0 0.14 12.1 0.4 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CCH62971.1 - 0.00018 21.8 0.2 1 9.8 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain DUF3349 PF11829.8 CCH62971.1 - 0.19 12.5 0.1 1.9 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Diphthamide_syn PF01866.17 CCH62972.1 - 5.4e-63 213.2 0.7 8.3e-63 212.6 0.7 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DUF4116 PF13475.6 CCH62972.1 - 0.092 12.5 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) Amidohydro_1 PF01979.20 CCH62973.1 - 8.9e-07 28.5 0.0 1.7e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 CCH62973.1 - 4e-05 23.6 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Ribosomal_L1 PF00687.21 CCH62974.1 - 3.6e-22 79.1 1.0 4.6e-22 78.8 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SUI1 PF01253.22 CCH62975.1 - 2e-18 66.7 0.0 5.5e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CCH62975.1 - 1.2e-08 35.6 1.3 2.5e-08 34.5 0.2 2.3 2 0 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 CCH62975.1 - 6e-06 26.1 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.20 CCH62975.1 - 0.011 15.7 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 PUA domain Phosphorylase PF00343.20 CCH62976.1 - 0 1024.3 0.4 0 1024.0 0.4 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3417 PF11897.8 CCH62976.1 - 0.74 10.3 3.2 1.1 9.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) Peptidase_S10 PF00450.22 CCH62977.1 - 1.1e-100 338.0 0.1 1.7e-100 337.4 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase CDC45 PF02724.14 CCH62977.1 - 0.00067 18.1 11.2 0.00093 17.6 11.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Mpp10 PF04006.12 CCH62977.1 - 0.0029 16.2 13.0 0.0041 15.6 13.0 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 CCH62977.1 - 0.0032 16.9 10.3 0.0055 16.1 10.3 1.3 1 0 0 1 1 1 1 BUD22 DUF4366 PF14283.6 CCH62977.1 - 0.0047 17.0 0.3 0.012 15.6 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Nop14 PF04147.12 CCH62977.1 - 0.0069 14.7 16.2 0.0092 14.3 16.2 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CCH62977.1 - 0.008 15.6 16.5 0.012 15.1 16.5 1.2 1 0 0 1 1 1 1 SDA1 Orf78 PF06024.12 CCH62977.1 - 0.017 15.4 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 Orf78 (ac78) Serinc PF03348.15 CCH62977.1 - 0.061 12.3 0.1 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RNA_pol_Rpc4 PF05132.14 CCH62977.1 - 0.11 12.9 0.3 0.19 12.1 0.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 YL1 PF05764.13 CCH62977.1 - 0.18 11.9 14.7 0.29 11.2 14.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein FAM60A PF15396.6 CCH62977.1 - 0.42 10.6 2.5 0.85 9.6 2.5 1.4 1 0 0 1 1 1 0 Protein Family FAM60A CD99L2 PF12301.8 CCH62977.1 - 0.64 10.3 7.7 0.13 12.5 3.1 2.0 1 1 1 2 2 2 0 CD99 antigen like protein 2 Presenilin PF01080.17 CCH62977.1 - 1 8.0 3.2 1.5 7.5 3.2 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CCH62977.1 - 2.3 6.9 7.2 3.4 6.3 7.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytomega_UL84 PF06284.11 CCH62977.1 - 7 5.0 5.4 10 4.4 5.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nop53 PF07767.11 CCH62977.1 - 9.9 5.4 18.0 17 4.7 18.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDP-OH_P_transf PF01066.21 CCH62978.1 - 2.9e-10 40.8 0.3 2.9e-10 40.8 0.3 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MMPL PF03176.15 CCH62978.1 - 0.12 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 MMPL family EutQ PF06249.12 CCH62978.1 - 0.15 11.8 0.3 0.27 11.0 0.3 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ ACOX PF01756.19 CCH62979.1 - 3.6e-45 153.7 0.0 8.8e-45 152.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CCH62979.1 - 1.2e-20 73.5 0.0 2.1e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CCH62979.1 - 5.8e-13 49.5 0.3 4.2e-12 46.7 0.1 2.5 2 1 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CCH62979.1 - 0.00063 20.0 0.0 0.0022 18.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF5365 PF17326.2 CCH62979.1 - 1.7 9.0 4.6 1.9 8.9 0.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5365) Clathrin PF00637.20 CCH62980.1 - 6.7e-175 574.0 61.2 1.2e-29 103.0 1.4 8.5 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CCH62980.1 - 5.4e-21 74.3 0.4 5.4e-19 67.9 0.0 3.8 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 CCH62980.1 - 7.8e-12 44.9 8.1 0.0019 18.4 0.5 5.8 5 0 0 5 5 5 4 Clathrin propeller repeat TPR_8 PF13181.6 CCH62980.1 - 6.4e-05 22.8 2.7 0.015 15.5 0.2 5.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCH62980.1 - 0.00042 20.2 4.3 1.6 9.0 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat Clathrin-link PF09268.10 CCH62980.1 - 0.00052 19.3 0.0 0.0036 16.6 0.0 2.5 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_12 PF13424.6 CCH62980.1 - 0.0039 17.4 1.7 1.6 9.0 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Ank_2 PF12796.7 CCH62980.1 - 0.085 13.5 0.1 1.2 9.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Vps39_1 PF10366.9 CCH62980.1 - 0.93 9.8 25.0 0.17 12.1 0.4 7.9 9 2 0 9 9 9 0 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 CCH62980.1 - 1.3 10.0 4.2 1.3e+02 3.8 0.0 5.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCH62980.1 - 2.2 8.6 14.0 3.2 8.1 0.1 6.6 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCH62980.1 - 9 6.3 13.9 5.1 7.1 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat SPT16 PF08644.11 CCH62981.1 - 2.9e-47 160.6 0.1 2.9e-47 160.6 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CCH62981.1 - 6.1e-45 152.9 0.1 6.1e-45 152.9 0.1 3.2 4 0 0 4 4 4 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CCH62981.1 - 3.8e-31 108.4 0.0 6.5e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CCH62981.1 - 1e-12 48.3 0.1 3.9e-12 46.4 0.1 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like AMPKBI PF04739.15 CCH62982.1 - 1.3e-29 102.3 0.9 5.1e-29 100.3 0.9 2.1 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CCH62982.1 - 2.1e-29 101.6 0.0 7.1e-29 99.9 0.0 1.9 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase zf-C2H2 PF00096.26 CCH62983.1 - 6.6e-10 38.9 14.8 2e-05 24.8 1.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCH62983.1 - 1.4e-08 34.8 17.6 1.6e-06 28.2 3.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCH62983.1 - 9.6e-07 29.1 11.6 0.00068 20.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCH62983.1 - 0.0047 17.2 5.2 0.087 13.1 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CCH62983.1 - 0.13 12.6 4.7 0.25 11.6 4.7 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CCH62983.1 - 0.16 12.0 0.3 0.16 12.0 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CCH62983.1 - 0.31 11.5 5.0 2.9 8.4 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CCH62983.1 - 1.1 9.1 12.1 0.71 9.7 0.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain PX PF00787.24 CCH62984.1 - 2e-09 37.4 0.2 6.9e-09 35.7 0.2 1.9 1 0 0 1 1 1 1 PX domain COX5A PF02284.16 CCH62984.1 - 0.088 12.8 0.3 6.2 6.9 0.1 3.3 3 0 0 3 3 3 0 Cytochrome c oxidase subunit Va WD40 PF00400.32 CCH62985.1 - 5e-10 39.8 14.3 2.1e-05 25.2 0.7 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH62985.1 - 4.2e-08 33.4 0.0 0.001 19.3 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4028 PF13220.6 CCH62986.1 - 0.1 12.3 0.2 0.31 10.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) DUF5364 PF17322.2 CCH62987.1 - 3.8e-18 66.5 11.2 4.6e-18 66.2 11.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5364) DUF572 PF04502.13 CCH62987.1 - 0.71 9.4 9.8 0.79 9.3 9.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) ABC_tran PF00005.27 CCH62988.1 - 1.5e-48 164.8 1.2 1.4e-23 83.9 0.0 2.8 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCH62988.1 - 3.2e-22 78.4 2.7 3.2e-22 78.4 2.7 2.9 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 CCH62988.1 - 1.5e-18 67.7 6.1 4.7e-06 26.6 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCH62988.1 - 1.1e-08 34.8 7.4 0.03 13.7 0.2 4.8 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCH62988.1 - 1.4e-07 31.2 0.0 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCH62988.1 - 4.1e-07 30.4 0.0 0.054 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CCH62988.1 - 4.1e-07 30.0 0.8 0.00061 19.7 0.0 3.1 3 0 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 CCH62988.1 - 7.1e-07 29.8 0.3 0.0022 18.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 CCH62988.1 - 2.2e-06 27.7 0.1 0.0073 16.4 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA PF00004.29 CCH62988.1 - 7.1e-06 26.5 0.0 0.14 12.6 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCH62988.1 - 9.8e-06 25.9 0.1 0.07 13.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_23 PF13476.6 CCH62988.1 - 1.2e-05 25.9 17.2 0.022 15.2 0.0 4.3 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 CCH62988.1 - 3.4e-05 23.7 11.6 0.038 13.7 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.12 CCH62988.1 - 4.7e-05 23.4 0.5 0.29 11.0 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.6 CCH62988.1 - 6.3e-05 23.4 0.0 0.21 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 CCH62988.1 - 6.5e-05 23.2 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CCH62988.1 - 9.5e-05 22.6 0.0 0.2 11.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CCH62988.1 - 0.00018 21.6 0.0 0.8 9.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain MCM PF00493.23 CCH62988.1 - 0.00023 20.3 0.1 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_24 PF13479.6 CCH62988.1 - 0.00044 20.0 0.6 0.38 10.5 0.1 3.4 3 1 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CCH62988.1 - 0.00085 18.6 2.2 0.42 9.8 0.0 3.7 4 1 0 4 4 3 1 NB-ARC domain Rad17 PF03215.15 CCH62988.1 - 0.0011 18.9 0.0 0.84 9.5 0.0 2.6 3 0 0 3 3 2 1 Rad17 P-loop domain Roc PF08477.13 CCH62988.1 - 0.0019 18.4 0.0 0.87 9.8 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CCH62988.1 - 0.0021 17.2 0.2 2.2 7.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) VirE PF05272.11 CCH62988.1 - 0.0037 17.0 0.0 0.35 10.6 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E TsaE PF02367.17 CCH62988.1 - 0.004 17.1 0.2 1.7 8.7 0.0 2.9 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 CCH62988.1 - 0.0041 17.2 5.0 1.8 8.6 0.0 3.9 3 1 1 4 4 3 1 Dynamin family AAA_5 PF07728.14 CCH62988.1 - 0.0059 16.6 0.0 3.5 7.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 CCH62988.1 - 0.007 15.6 1.5 2.1 7.4 0.0 3.2 2 2 1 4 4 4 1 G-protein alpha subunit AAA_7 PF12775.7 CCH62988.1 - 0.0075 15.8 0.2 1.4 8.4 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region NTPase_1 PF03266.15 CCH62988.1 - 0.0075 16.2 0.1 0.61 10.0 0.1 2.6 2 0 0 2 2 2 1 NTPase T2SSE PF00437.20 CCH62988.1 - 0.0082 15.2 0.0 0.077 12.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 CCH62988.1 - 0.0096 15.7 0.1 0.29 10.9 0.0 3.0 4 0 0 4 4 4 1 IstB-like ATP binding protein CLP1_P PF16575.5 CCH62988.1 - 0.011 15.5 0.3 5.2 6.8 0.0 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 CCH62988.1 - 0.021 14.5 0.1 6.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CCH62988.1 - 0.022 13.7 0.2 1.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CCH62988.1 - 0.038 13.6 0.0 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CCH62988.1 - 0.049 13.7 8.9 0.27 11.3 0.0 3.4 4 1 0 4 4 2 0 Helicase HerA, central domain AAA_30 PF13604.6 CCH62988.1 - 0.052 13.3 1.9 1.6 8.4 0.1 3.2 3 1 0 3 3 3 0 AAA domain FeoB_N PF02421.18 CCH62988.1 - 0.059 12.9 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.6 CCH62988.1 - 0.084 13.3 1.4 32 4.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 CCH62988.1 - 0.12 12.2 0.2 24 4.6 0.1 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 CCH62988.1 - 0.26 11.1 6.2 2.6 7.9 0.0 3.2 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_27 PF13514.6 CCH62988.1 - 0.37 10.3 8.4 0.91 9.1 0.0 3.1 4 0 0 4 4 2 0 AAA domain DASH_Dad2 PF08654.10 CCH62989.1 - 0.0092 16.4 1.3 0.0092 16.4 1.3 3.5 3 2 0 3 3 3 1 DASH complex subunit Dad2 Mrr_N PF14338.6 CCH62989.1 - 2.1 8.6 4.4 12 6.1 0.1 3.6 3 0 0 3 3 3 0 Mrr N-terminal domain GATA PF00320.27 CCH62991.1 - 3.4e-15 55.4 5.1 9.7e-15 53.9 5.1 1.9 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCH62991.1 - 0.14 11.7 3.3 0.17 11.5 1.6 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Rib_recp_KP_reg PF05104.12 CCH62991.1 - 6.8 7.7 10.4 10 7.1 8.8 2.1 1 1 0 1 1 1 0 Ribosome receptor lysine/proline rich region XPG_I PF00867.18 CCH62992.1 - 1.5e-25 89.4 0.0 1.8e-23 82.7 0.0 3.4 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CCH62992.1 - 7.8e-06 26.3 0.0 2.6e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain PMSR PF01625.21 CCH62993.1 - 7.5e-51 172.3 0.5 9.1e-51 172.1 0.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase IL28A PF15177.6 CCH62994.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 2.6 2 1 0 2 2 2 1 Interleukin-28A SAPS PF04499.15 CCH62995.1 - 2e-113 379.8 54.3 2e-113 379.8 54.3 3.2 2 2 0 2 2 2 1 SIT4 phosphatase-associated protein HEPN_RES_NTD1 PF18870.1 CCH62995.1 - 0.021 15.0 0.1 0.073 13.3 0.1 1.9 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 DnaJ PF00226.31 CCH62996.1 - 1.5e-13 50.6 5.5 2.9e-13 49.7 5.5 1.5 1 0 0 1 1 1 1 DnaJ domain Adaptin_binding PF10199.9 CCH62998.1 - 1.5e-05 25.6 2.2 0.00076 20.1 2.2 2.4 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Peptidase_M20 PF01546.28 CCH62999.1 - 4.4e-33 114.7 0.0 5.8e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCH62999.1 - 6.1e-13 48.6 0.0 9.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CCH62999.1 - 0.0015 18.2 0.0 0.0075 16.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 GIDA PF01134.22 CCH63000.1 - 2.7e-154 514.0 0.0 3.5e-154 513.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CCH63000.1 - 8.2e-64 215.7 0.1 1.1e-63 215.2 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 CCH63000.1 - 8.4e-07 28.5 0.6 3.2e-06 26.6 0.5 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCH63000.1 - 8.3e-06 25.4 0.2 1.2e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCH63000.1 - 6.9e-05 22.1 3.5 0.0026 16.9 3.5 2.3 1 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 CCH63000.1 - 0.0025 17.5 1.0 1.6 8.2 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CCH63000.1 - 0.035 13.4 0.3 0.069 12.4 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CCH63000.1 - 0.036 14.6 0.2 0.084 13.5 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CCH63000.1 - 0.042 12.9 0.4 0.35 9.9 0.8 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CCH63000.1 - 0.043 12.5 2.3 1.7 7.3 1.0 2.3 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 CCH63000.1 - 0.084 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.6 CCH63000.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cse1 PF08506.10 CCH63001.1 - 7.3e-166 551.5 12.8 7.3e-166 551.5 12.8 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CCH63001.1 - 2.1e-108 362.7 7.0 3.8e-108 361.8 7.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CCH63001.1 - 2.3e-17 62.7 2.6 1.7e-16 59.9 0.0 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCH63001.1 - 0.00022 21.3 5.9 0.0028 17.7 0.1 4.6 4 0 0 4 4 4 1 Exportin 1-like protein Ank PF00023.30 CCH63002.1 - 7.6e-11 42.0 0.7 0.00047 20.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CCH63002.1 - 2.6e-10 39.6 0.2 0.0018 18.6 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CCH63002.1 - 3.9e-09 37.0 0.2 7.9e-09 36.0 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCH63002.1 - 2.5e-07 30.8 0.4 0.0071 16.6 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH63002.1 - 1.4e-06 28.7 0.7 0.0031 18.1 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) S36_mt PF10937.8 CCH63003.1 - 6.2e-24 85.8 0.1 8.1e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Ribosomal_L18_c PF14204.6 CCH63004.1 - 1.4 9.9 5.7 0.54 11.2 2.3 2.1 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Ppx-GppA PF02541.16 CCH63005.1 - 1.7e-54 185.2 0.0 2.2e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family CSN8_PSD8_EIF3K PF10075.9 CCH63006.1 - 4.9e-16 59.0 0.1 7.5e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CCH63006.1 - 4.3e-06 26.3 0.1 5.4e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP family Vip3A_N PF12495.8 CCH63006.1 - 0.026 14.4 2.1 0.046 13.6 2.1 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Hexokinase_2 PF03727.16 CCH63007.1 - 1.3e-73 247.4 0.0 1.7e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCH63007.1 - 1.6e-70 237.1 0.0 2.5e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 CCH63007.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain YdjM PF04307.14 CCH63008.1 - 0.088 12.1 1.3 0.18 11.1 1.3 1.6 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Oxidored_FMN PF00724.20 CCH63010.1 - 2.5e-121 405.1 0.0 2.9e-121 404.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SCO1-SenC PF02630.14 CCH63010.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 SCO1/SenC Sugar_tr PF00083.24 CCH63011.1 - 5.3e-161 536.5 36.5 6e-161 536.3 36.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCH63011.1 - 3.2e-30 105.3 35.0 1.5e-27 96.4 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 CCH63011.1 - 0.036 13.5 1.9 1 8.9 0.4 3.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family MFS_3 PF05977.13 CCH63011.1 - 0.063 11.7 8.1 0.014 13.8 3.8 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 CCH63011.1 - 0.43 11.1 4.3 15 6.2 1.0 3.5 3 0 0 3 3 3 0 Phage holin family 2 DUF1772 PF08592.11 CCH63011.1 - 0.64 10.3 3.7 7.7 6.8 3.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) hDGE_amylase PF14701.6 CCH63012.1 - 4e-171 569.9 4.4 5.8e-171 569.4 4.4 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CCH63012.1 - 1.8e-129 432.1 0.0 2.7e-129 431.4 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CCH63012.1 - 4.8e-79 265.6 0.0 9.7e-79 264.6 0.0 1.6 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CCH63012.1 - 7.1e-25 87.0 0.3 1.8e-23 82.5 0.1 2.7 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CCH63012.1 - 0.00019 21.1 0.9 0.0016 18.1 0.7 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain TMEM219 PF14940.6 CCH63012.1 - 0.092 12.3 0.3 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 Transmembrane 219 Glycos_transf_2 PF00535.26 CCH63013.1 - 2.2e-30 105.7 0.0 3e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCH63013.1 - 1.2e-05 25.3 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CCH63013.1 - 0.007 15.9 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Sec23_trunk PF04811.15 CCH63014.1 - 1.3e-67 227.9 0.0 1.8e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CCH63014.1 - 9.2e-30 103.3 0.6 1.8e-29 102.3 0.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCH63014.1 - 6.5e-27 93.4 0.0 1.8e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCH63014.1 - 3.2e-12 46.3 8.4 5.9e-12 45.4 8.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCH63014.1 - 5.5e-12 45.4 0.0 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CCH63014.1 - 0.0013 18.1 2.7 0.0029 17.0 2.7 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Tagatose_6_P_K PF08013.11 CCH63014.1 - 0.2 10.3 0.5 0.4 9.3 0.1 1.6 2 0 0 2 2 2 0 Tagatose 6 phosphate kinase zf-MIZ PF02891.20 CCH63014.1 - 0.4 10.5 2.7 1 9.2 2.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger NBP1 PF08537.10 CCH63015.1 - 6.3e-40 137.6 28.8 7.6e-40 137.3 28.8 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Csm1_N PF18504.1 CCH63015.1 - 0.019 15.3 1.1 0.019 15.3 1.1 3.4 3 1 1 4 4 4 0 Csm1 N-terminal domain Lzipper-MIP1 PF14389.6 CCH63015.1 - 0.067 13.5 4.6 0.2 12.0 4.6 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4140 PF13600.6 CCH63015.1 - 0.13 12.7 0.4 0.47 10.9 0.2 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) EKAL PF17986.1 CCH63015.1 - 0.27 11.3 1.1 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain FlxA PF14282.6 CCH63015.1 - 1.8 8.6 11.0 0.17 11.9 2.5 3.0 2 1 1 3 3 3 0 FlxA-like protein Prefoldin PF02996.17 CCH63015.1 - 2.9 7.8 10.4 0.12 12.3 1.4 2.9 2 1 1 3 3 3 0 Prefoldin subunit Putative_PNPOx PF01243.20 CCH63016.1 - 9.3e-17 61.0 0.0 3.6e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 CCH63016.1 - 0.00011 22.2 0.2 0.00083 19.4 0.2 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 CCH63016.1 - 0.0032 17.5 0.0 0.029 14.4 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CCH63016.1 - 0.037 13.6 0.1 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like PWWP PF00855.17 CCH63017.1 - 8.2e-13 48.6 0.4 2.5e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 PWWP domain ABC_membrane PF00664.23 CCH63019.1 - 0.021 14.5 1.0 0.025 14.2 1.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region Aa_trans PF01490.18 CCH63019.1 - 0.052 12.3 2.0 0.081 11.6 2.0 1.3 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein Med10 PF09748.9 CCH63020.1 - 3.1e-38 130.4 0.5 4.8e-38 129.8 0.5 1.3 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Laminin_II PF06009.12 CCH63020.1 - 0.033 14.2 1.9 0.038 14.0 0.9 1.5 2 0 0 2 2 2 0 Laminin Domain II DUF615 PF04751.14 CCH63020.1 - 0.039 13.9 0.9 0.83 9.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF615) DUF3877 PF12993.7 CCH63020.1 - 0.052 13.4 0.1 0.083 12.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) BST2 PF16716.5 CCH63020.1 - 0.098 13.3 1.1 0.25 11.9 0.5 1.9 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PBS_linker_poly PF00427.21 CCH63020.1 - 0.13 12.3 0.8 0.67 10.0 0.1 2.3 2 1 1 3 3 3 0 Phycobilisome Linker polypeptide NPV_P10 PF05531.12 CCH63020.1 - 1 9.9 5.9 10 6.6 0.4 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Ras PF00071.22 CCH63021.1 - 1.3e-55 187.5 0.0 1.5e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCH63021.1 - 2.5e-21 76.1 0.0 5e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCH63021.1 - 4.6e-07 29.4 0.0 6.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCH63021.1 - 0.03 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Fmp27_WPPW PF10359.9 CCH63022.1 - 1.3e-109 367.2 1.3 3.6e-109 365.8 1.3 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 CCH63022.1 - 4.9e-83 279.7 72.8 8e-83 279.0 72.8 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 CCH63022.1 - 2.9e-65 221.0 10.4 7.4e-44 150.4 5.7 2.9 1 1 1 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CCH63022.1 - 5.8e-59 198.7 0.7 1.5e-58 197.3 0.7 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCH63022.1 - 2.3e-52 177.0 0.4 7.6e-51 172.1 0.7 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCH63022.1 - 9.2e-30 103.4 0.1 1e-28 100.0 0.1 3.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain AAA_lid_4 PF17864.1 CCH63022.1 - 0.025 14.3 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 RuvB AAA lid domain RRM_1 PF00076.22 CCH63023.1 - 2.7e-05 23.9 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N36 PF11438.8 CCH63023.1 - 1.6 8.6 32.7 1.5 8.7 0.7 5.8 6 0 0 6 6 6 0 36-mer N-terminal peptide of the N protein (N36) ORC4_C PF14629.6 CCH63024.1 - 6.4e-41 140.1 4.0 1.4e-40 139.0 4.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CCH63024.1 - 7.8e-05 23.1 0.0 0.00022 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCH63024.1 - 0.00024 21.4 0.7 0.0021 18.4 0.1 2.9 3 1 0 3 3 3 1 AAA domain AbiJ_NTD5 PF18865.1 CCH63024.1 - 0.0086 15.9 0.8 1.7 8.5 0.1 2.8 2 0 0 2 2 2 2 AbiJ N-terminal domain 5 AAA_7 PF12775.7 CCH63024.1 - 0.043 13.3 0.4 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Pneumo_matrix PF03393.16 CCH63024.1 - 0.087 12.0 1.5 0.21 10.8 0.5 2.1 2 1 0 2 2 2 0 Pneumovirus matrix protein Pkinase PF00069.25 CCH63025.1 - 7e-75 251.8 0.0 1.2e-74 251.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH63025.1 - 6.6e-30 104.3 0.1 4.5e-29 101.5 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 CCH63026.1 - 7.5e-14 52.0 0.1 5.8e-09 36.2 0.0 2.8 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 CCH63026.1 - 2.7e-09 37.0 0.1 8.8e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF2_C PF09173.11 CCH63027.1 - 1.9e-34 117.8 0.4 4.5e-34 116.6 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CCH63027.1 - 3e-23 82.4 0.2 2.7e-22 79.3 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CCH63027.1 - 1.2e-11 44.8 0.5 3.6e-11 43.3 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCH63027.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCH63027.1 - 0.0039 17.1 0.1 0.056 13.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase ProQ_C PF17516.2 CCH63027.1 - 0.017 14.6 0.5 0.038 13.4 0.5 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain MMR_HSR1_Xtn PF16897.5 CCH63027.1 - 0.052 13.6 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MFS_1 PF07690.16 CCH63028.1 - 3.6e-25 88.6 28.2 1.4e-15 57.1 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CCH63028.1 - 1.2e-11 43.8 10.7 3.5e-05 22.5 0.6 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 CCH63028.1 - 0.00015 20.8 7.9 0.00015 20.8 7.9 2.4 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 CCH63028.1 - 0.002 16.5 12.0 0.0093 14.3 1.4 2.5 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S26 PF10502.9 CCH63028.1 - 0.11 12.3 0.1 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 Sugar_tr PF00083.24 CCH63028.1 - 0.14 11.0 25.5 1 8.2 25.6 2.7 1 1 0 1 1 1 0 Sugar (and other) transporter Antimicrobial24 PF16049.5 CCH63028.1 - 2.9 8.0 4.2 1.1 9.3 0.7 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide Ribosomal_S7 PF00177.21 CCH63029.1 - 6e-37 126.6 2.7 8.7e-37 126.1 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Baculo_IE-1 PF05290.11 CCH63029.1 - 0.087 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) ComS PF17584.2 CCH63030.1 - 0.061 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Bacillus competence protein S JmjC PF02373.22 CCH63031.1 - 1.2e-35 122.4 1.7 1.5e-35 122.0 0.2 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 CCH63031.1 - 3e-13 49.5 0.5 1.1e-12 47.6 0.4 2.1 2 0 0 2 2 2 1 jmjN domain PHD PF00628.29 CCH63031.1 - 2.1e-11 43.5 2.8 2.1e-11 43.5 2.8 2.4 2 0 0 2 2 2 1 PHD-finger PfkB PF00294.24 CCH63032.1 - 9e-72 241.9 1.7 1.1e-71 241.6 1.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CCH63032.1 - 1.3e-05 24.7 0.1 2.9e-05 23.6 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Lipase_3 PF01764.25 CCH63033.1 - 1.4e-35 122.2 0.0 2.2e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CCH63033.1 - 0.036 13.6 0.1 4.9 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CCH63033.1 - 0.057 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 CCH63033.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Folate_carrier PF01770.18 CCH63033.1 - 0.24 10.1 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier G-alpha PF00503.20 CCH63034.1 - 2.2e-93 313.3 36.6 2.2e-93 313.3 36.6 2.9 1 1 1 2 2 2 1 G-protein alpha subunit Arf PF00025.21 CCH63034.1 - 4.4e-16 58.8 0.8 1.3e-10 41.1 0.4 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CCH63034.1 - 0.088 13.0 7.6 2.9 8.2 0.1 3.5 3 1 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Macoilin PF09726.9 CCH63034.1 - 5.5 5.4 50.1 0.14 10.7 13.1 2.1 2 0 0 2 2 2 0 Macoilin family RNA_pol_Rpb8 PF03870.15 CCH63035.1 - 3.3e-46 156.9 0.0 3.7e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CCH63035.1 - 4.5e-06 26.7 0.2 0.062 13.4 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G SPC22 PF04573.12 CCH63035.1 - 0.078 12.5 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Signal peptidase subunit TcpA PF05946.12 CCH63035.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA DUF2407_C PF13373.6 CCH63036.1 - 1.1e-39 135.7 2.2 1.4e-39 135.5 0.5 1.8 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CCH63036.1 - 5.2e-21 75.2 0.2 1e-20 74.3 0.2 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Zn_clus PF00172.18 CCH63037.1 - 1.1e-05 25.4 6.7 2.3e-05 24.4 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CCH63037.1 - 0.00061 19.8 0.0 0.0029 17.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold CtaG_Cox11 PF04442.14 CCH63038.1 - 9.5e-58 194.5 0.6 2.9e-57 192.9 0.0 1.9 2 1 1 3 3 3 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Lactonase PF10282.9 CCH63039.1 - 0.029 13.6 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Ribosomal_L5e PF17144.4 CCH63040.1 - 1.5e-82 275.4 0.8 1.6e-82 275.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CCH63040.1 - 7.9e-32 110.1 3.8 7.9e-32 110.1 3.8 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CCH63040.1 - 0.0027 18.0 0.4 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Com_YlbF PF06133.11 CCH63040.1 - 0.046 14.3 2.5 0.11 13.2 2.5 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Thr_synth_N PF14821.6 CCH63040.1 - 0.049 13.9 0.4 0.91 9.8 0.0 2.7 3 0 0 3 3 3 0 Threonine synthase N terminus Phage_holin_3_3 PF16083.5 CCH63040.1 - 0.079 13.1 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III SPT6_acidic PF14632.6 CCH63040.1 - 6.7 7.4 7.1 23 5.7 7.1 1.9 1 1 0 1 1 1 0 Acidic N-terminal SPT6 RFC1 PF08519.12 CCH63041.1 - 2.7e-60 203.1 2.9 2.8e-60 203.0 1.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CCH63041.1 - 1.2e-11 45.2 0.1 6.3e-11 42.8 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CCH63041.1 - 4.8e-11 42.9 0.0 2.5e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CCH63041.1 - 3.3e-05 23.9 0.0 0.00011 22.1 0.0 2.0 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CCH63041.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CCH63041.1 - 0.00014 22.0 0.0 0.00055 20.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCH63041.1 - 0.0025 18.2 0.0 0.0078 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 CCH63041.1 - 0.0046 17.4 4.6 0.0073 16.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CCH63041.1 - 0.0063 17.1 0.2 0.034 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCH63041.1 - 0.0068 16.7 0.0 0.071 13.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCH63041.1 - 0.0074 16.7 0.0 0.03 14.7 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CCH63041.1 - 0.017 15.2 0.0 0.093 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCH63041.1 - 0.025 14.5 0.0 0.24 11.3 0.0 2.4 1 1 0 1 1 1 0 NACHT domain AAA_assoc_2 PF16193.5 CCH63041.1 - 0.05 14.0 0.7 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA C-terminal domain GRAB PF10375.9 CCH63042.1 - 3e-07 30.1 7.0 4.1e-07 29.6 2.2 2.6 2 0 0 2 2 2 1 GRIP-related Arf-binding domain ERM PF00769.19 CCH63042.1 - 0.0025 17.7 63.9 0.038 13.8 28.1 3.2 1 1 2 3 3 3 2 Ezrin/radixin/moesin family KLRAQ PF10205.9 CCH63042.1 - 0.0042 17.3 11.6 0.0042 17.3 11.6 5.5 1 1 4 5 5 5 1 Predicted coiled-coil domain-containing protein ATG16 PF08614.11 CCH63042.1 - 0.0062 16.8 69.4 0.019 15.2 19.3 4.2 1 1 3 4 4 4 2 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CCH63042.1 - 0.011 15.0 7.6 0.011 15.0 7.6 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) DUF4472 PF14739.6 CCH63042.1 - 0.019 15.7 20.6 0.019 15.7 20.6 4.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) CEP63 PF17045.5 CCH63042.1 - 0.047 13.6 62.8 0.011 15.6 40.1 2.3 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Spc7 PF08317.11 CCH63042.1 - 0.13 11.2 72.7 0.037 12.9 14.1 4.6 1 1 3 4 4 4 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CCH63042.1 - 0.13 12.3 60.4 0.11 12.6 0.8 7.2 6 1 0 7 7 7 0 bZIP transcription factor Tropomyosin PF00261.20 CCH63042.1 - 0.16 11.4 63.9 0.032 13.6 37.7 3.3 2 1 1 3 3 3 0 Tropomyosin Fez1 PF06818.15 CCH63042.1 - 0.19 12.2 60.3 0.072 13.5 25.0 3.3 1 1 2 3 3 3 0 Fez1 FUSC PF04632.12 CCH63042.1 - 0.28 9.7 4.2 3.1 6.2 0.4 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Golgin_A5 PF09787.9 CCH63042.1 - 0.41 10.1 70.3 0.041 13.3 19.1 4.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 CCH63042.1 - 0.5 10.6 67.8 0.09 13.0 12.8 5.5 1 1 5 6 6 6 0 TATA element modulatory factor 1 TATA binding Uso1_p115_C PF04871.13 CCH63042.1 - 0.63 10.4 68.5 0.48 10.8 18.6 5.2 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADIP PF11559.8 CCH63042.1 - 4.9 7.2 68.5 0.16 12.1 19.8 4.4 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 CCH63042.1 - 5 7.2 70.1 4.3 7.4 14.4 4.9 2 2 1 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 CCH63042.1 - 5.7 7.0 40.3 0.5 10.4 10.1 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Acetyltransf_10 PF13673.7 CCH63043.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain YqeY PF09424.10 CCH63044.1 - 1.3e-20 73.9 12.2 1.5e-20 73.7 11.3 1.5 1 1 1 2 2 2 1 Yqey-like protein Nucleopor_Nup85 PF07575.13 CCH63044.1 - 0.0079 14.8 3.2 0.011 14.4 3.2 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin Pex24p PF06398.11 CCH63044.1 - 0.17 10.8 1.8 0.18 10.8 0.9 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin GerE PF00196.19 CCH63044.1 - 0.2 11.2 1.9 0.24 11.0 0.4 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family YEATS PF03366.16 CCH63045.1 - 8.7e-17 60.9 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family TRF PF08558.10 CCH63046.1 - 3.9e-18 65.9 16.7 2e-16 60.4 15.8 2.7 2 1 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CCH63046.1 - 8.2e-06 25.9 0.8 1.9e-05 24.8 0.8 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH63046.1 - 0.019 15.2 0.3 0.062 13.6 0.3 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain IBN_N PF03810.19 CCH63047.1 - 9e-18 64.0 1.9 2.1e-15 56.4 0.4 3.2 3 0 0 3 3 3 2 Importin-beta N-terminal domain Mog1 PF04603.12 CCH63047.1 - 0.0085 16.5 0.6 0.028 14.8 0.2 2.0 2 0 0 2 2 2 1 Ran-interacting Mog1 protein ANTH PF07651.16 CCH63048.1 - 0.00094 18.2 2.4 0.0013 17.7 2.4 1.1 1 0 0 1 1 1 1 ANTH domain TetR_C_24 PF17932.1 CCH63048.1 - 0.37 11.1 1.6 8.6 6.7 0.3 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FliT PF05400.13 CCH63048.1 - 0.75 10.6 6.4 28 5.6 4.4 2.3 2 0 0 2 2 2 0 Flagellar protein FliT XhlA PF10779.9 CCH63048.1 - 3.1 8.1 5.6 1.6 9.0 0.6 2.6 3 0 0 3 3 3 0 Haemolysin XhlA Ribonuclease_T2 PF00445.18 CCH63049.1 - 1e-41 143.2 4.7 1.6e-41 142.5 4.7 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family PSP94 PF05825.11 CCH63049.1 - 0.037 14.6 0.5 0.1 13.1 0.5 1.8 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) Nop52 PF05997.12 CCH63050.1 - 8.7e-70 234.9 2.7 1e-69 234.7 2.7 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 GlutR_dimer PF00745.20 CCH63050.1 - 0.01 16.2 0.0 1.3 9.5 0.0 2.4 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain SecE PF00584.20 CCH63051.1 - 6.3e-13 48.4 0.1 7.2e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CBFD_NFYB_HMF PF00808.23 CCH63052.1 - 2.2e-11 43.8 0.0 3.3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Oxidored_FMN PF00724.20 CCH63053.1 - 1.3e-122 409.4 0.0 1.4e-122 409.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCH63053.1 - 0.036 14.3 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5442) TENA_THI-4 PF03070.16 CCH63054.1 - 0.00032 20.6 4.2 0.0006 19.7 4.2 1.5 1 1 0 1 1 1 1 TENA/THI-4/PQQC family MFA1_2 PF17317.2 CCH63055.1 - 7.1e-24 83.3 0.1 7.5e-24 83.2 0.1 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 CRAL_TRIO_2 PF13716.6 CCH63056.1 - 8e-27 94.1 2.3 1.9e-26 92.9 2.3 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CCH63056.1 - 1.4e-12 47.7 0.3 1.4e-11 44.4 0.3 2.6 1 1 0 1 1 1 1 RhoGAP domain SEF14_adhesin PF06443.11 CCH63056.1 - 0.086 12.7 0.4 0.21 11.5 0.4 1.6 1 0 0 1 1 1 0 SEF14-like adhesin RasGEF PF00617.19 CCH63057.1 - 2.8e-45 154.7 2.7 2.8e-45 154.7 2.7 3.2 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CCH63057.1 - 7.1e-14 51.9 0.9 8.7e-13 48.4 0.9 3.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 CCH63057.1 - 0.0027 17.3 0.1 0.0072 15.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCH63057.1 - 0.016 15.1 0.1 0.045 13.6 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain NUMOD1 PF07453.13 CCH63057.1 - 0.81 10.0 3.7 35 4.8 0.3 4.0 2 0 0 2 2 2 0 NUMOD1 domain Aconitase PF00330.20 CCH63058.1 - 4.3e-142 474.4 0.0 5.3e-142 474.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCH63058.1 - 1e-38 132.6 0.0 2.5e-38 131.3 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Beta-prism_lec PF16458.5 CCH63058.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Beta-prism lectin SPX PF03105.19 CCH63059.1 - 7.1e-38 131.5 24.4 1.4e-20 74.6 14.3 2.1 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 CCH63059.1 - 2.6e-19 69.5 60.0 6.2e-17 61.7 32.6 2.2 1 1 1 2 2 2 2 Citrate transporter UCH PF00443.29 CCH63060.1 - 9.9e-78 261.2 0.0 1.1e-75 254.5 0.0 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PfkB PF00294.24 CCH63061.1 - 4.3e-52 177.3 0.6 1.4e-51 175.6 0.6 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 CCH63062.1 - 2.5e-08 33.9 9.9 5.4e-08 32.8 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF749 PF05370.11 CCH63063.1 - 0.013 15.6 2.3 9 6.5 0.1 4.0 3 2 0 3 3 3 0 Domain of unknown function (DUF749) AAA PF00004.29 CCH63064.1 - 5.1e-98 324.6 0.0 5.4e-48 162.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCH63064.1 - 7.7e-25 86.4 8.0 2.4e-13 49.7 1.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CCH63064.1 - 1.9e-18 66.4 0.5 6e-18 64.8 0.5 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CCH63064.1 - 7.1e-14 51.8 0.0 1.2e-05 25.1 0.0 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCH63064.1 - 8.8e-14 52.0 0.1 3.3e-07 30.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCH63064.1 - 6.4e-13 49.4 0.1 0.00017 22.0 0.0 4.7 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 CCH63064.1 - 9.3e-12 45.1 0.4 8.1e-06 25.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCH63064.1 - 1.2e-11 44.9 0.0 1e-05 25.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCH63064.1 - 2.9e-09 36.6 0.1 0.0017 17.7 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 CCH63064.1 - 4e-08 32.9 0.0 1e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CCH63064.1 - 9.6e-08 32.4 4.4 0.076 13.3 0.1 4.5 3 2 1 4 4 4 2 AAA domain AAA_14 PF13173.6 CCH63064.1 - 2.3e-07 30.9 0.0 0.026 14.5 0.0 3.4 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 CCH63064.1 - 2.5e-07 31.1 0.0 0.012 15.9 0.0 3.1 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CCH63064.1 - 3.3e-07 29.9 0.3 0.026 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CCH63064.1 - 8e-07 29.0 0.1 0.032 14.0 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein ATPase PF06745.13 CCH63064.1 - 1.3e-06 28.0 1.0 0.35 10.2 0.0 3.9 2 1 0 3 3 3 2 KaiC Vps4_C PF09336.10 CCH63064.1 - 1.8e-06 27.8 1.5 5.9e-05 23.0 0.1 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 CCH63064.1 - 6e-06 26.8 0.0 0.22 12.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CCH63064.1 - 6.6e-06 26.0 0.0 0.092 12.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CCH63064.1 - 9.8e-06 25.2 0.1 0.087 12.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Bac_DnaA PF00308.18 CCH63064.1 - 1.1e-05 25.4 0.0 0.091 12.6 0.0 3.3 3 0 0 3 3 3 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 CCH63064.1 - 1.4e-05 24.3 0.0 0.16 11.1 0.0 3.0 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CCH63064.1 - 1.7e-05 25.1 0.4 0.59 10.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 CCH63064.1 - 2.1e-05 24.3 0.1 0.21 11.3 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 CCH63064.1 - 2.3e-05 24.0 5.4 0.073 12.6 0.4 4.0 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 CCH63064.1 - 4e-05 24.2 0.1 0.12 12.9 0.0 3.8 3 1 0 3 3 2 1 ABC transporter AAA_17 PF13207.6 CCH63064.1 - 7.7e-05 23.1 0.3 0.59 10.6 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_3 PF07726.11 CCH63064.1 - 0.00012 21.9 0.0 0.78 9.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CCH63064.1 - 0.00013 21.3 0.0 0.12 11.5 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) PhoH PF02562.16 CCH63064.1 - 0.00014 21.4 2.7 0.2 11.1 0.1 2.8 3 0 0 3 3 3 2 PhoH-like protein TsaE PF02367.17 CCH63064.1 - 0.00034 20.6 0.0 0.64 10.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CCH63064.1 - 0.00041 20.4 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CCH63064.1 - 0.00068 19.0 0.0 1.1 8.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CCH63064.1 - 0.00096 18.9 0.3 2.4 7.9 0.1 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CCH63064.1 - 0.0016 18.4 0.1 2.3 8.1 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_11 PF13086.6 CCH63064.1 - 0.0049 16.7 7.5 1 9.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CCH63064.1 - 0.0095 15.9 4.2 3.1 7.7 0.1 4.5 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CCH63064.1 - 0.015 14.6 0.0 7.6 5.8 0.0 3.2 3 0 0 3 3 2 0 Zeta toxin Sigma54_activ_2 PF14532.6 CCH63064.1 - 0.015 15.4 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 CCH63064.1 - 0.019 14.4 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 CCH63064.1 - 0.031 13.5 0.2 2.3 7.4 0.0 3.1 2 2 0 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 CCH63064.1 - 0.033 13.4 0.0 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Zot PF05707.12 CCH63064.1 - 0.046 13.4 0.0 2.9 7.5 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 CCH63064.1 - 0.068 13.5 5.4 3.3 8.0 0.0 3.4 3 1 1 4 4 2 0 AAA domain NTPase_1 PF03266.15 CCH63064.1 - 0.074 13.0 1.5 8.4 6.3 0.0 3.9 4 0 0 4 4 3 0 NTPase Molydop_binding PF01568.21 CCH63064.1 - 0.092 12.8 0.1 0.35 10.9 0.1 2.0 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain HHV-5_US34A PF17087.5 CCH63064.1 - 0.1 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus US34A protein family eIF-1a PF01176.19 CCH63064.1 - 0.11 12.3 0.7 1.7 8.5 0.1 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 AAA_6 PF12774.7 CCH63064.1 - 0.14 11.1 0.5 5.4 5.9 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Viral_helicase1 PF01443.18 CCH63064.1 - 0.19 11.5 0.1 19 4.9 0.0 3.2 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase Cyclin_N PF00134.23 CCH63065.1 - 8e-16 57.9 0.1 1.9e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCH63065.1 - 3.9e-06 27.3 0.1 3.9e-06 27.3 0.1 2.4 2 1 0 2 2 2 1 Cyclin Na_Ca_ex PF01699.24 CCH63066.1 - 1.9e-47 161.0 35.5 4.8e-24 85.0 8.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein ERGIC_N PF13850.6 CCH63066.1 - 1.4 9.3 7.4 13 6.3 0.2 3.9 2 1 2 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3020 PF11223.8 CCH63067.1 - 5e-11 42.9 12.4 5e-11 42.9 12.4 11.8 7 2 3 10 10 10 1 Protein of unknown function (DUF3020) FBPase_2 PF06874.11 CCH63068.1 - 0.085 11.1 1.2 0.15 10.3 1.2 1.3 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Methyltransf_11 PF08241.12 CCH63068.1 - 0.096 13.4 0.0 1.5 9.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain SNARE PF05739.19 CCH63069.1 - 7.4e-06 25.9 0.2 7.4e-06 25.9 0.2 3.1 3 0 0 3 3 3 1 SNARE domain HrpB7 PF09486.10 CCH63069.1 - 0.0066 16.9 0.7 0.012 16.0 0.7 1.3 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Use1 PF09753.9 CCH63069.1 - 0.0083 15.9 7.5 0.057 13.1 7.5 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF4763 PF15960.5 CCH63069.1 - 0.011 15.1 7.7 0.089 12.1 1.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) MIS13 PF08202.11 CCH63069.1 - 0.016 14.5 11.7 0.021 14.1 11.7 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Ino80_Iec3 PF14612.6 CCH63069.1 - 0.024 15.3 8.0 0.03 15.0 8.0 1.1 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Laminin_II PF06009.12 CCH63069.1 - 0.025 14.6 10.4 2.4 8.2 2.6 3.0 2 1 1 3 3 3 0 Laminin Domain II SlyX PF04102.12 CCH63069.1 - 0.046 14.3 12.3 13 6.4 2.9 4.3 2 2 2 4 4 4 0 SlyX DUF1664 PF07889.12 CCH63069.1 - 0.055 13.5 8.0 2.1 8.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 CCH63069.1 - 0.067 12.9 7.0 0.27 10.9 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Allexi_40kDa PF05549.11 CCH63069.1 - 0.084 12.4 11.2 0.035 13.6 6.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein PI3K_1B_p101 PF10486.9 CCH63069.1 - 0.1 10.4 6.8 0.13 10.1 6.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TMPIT PF07851.13 CCH63069.1 - 0.14 11.4 7.0 0.28 10.4 1.6 2.1 1 1 1 2 2 2 0 TMPIT-like protein Exonuc_VII_L PF02601.15 CCH63069.1 - 0.23 11.0 9.2 0.4 10.2 9.2 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DivIVA PF05103.13 CCH63069.1 - 0.29 11.2 7.8 1.5 8.9 6.8 2.2 1 1 1 2 2 2 0 DivIVA protein Syntaxin_2 PF14523.6 CCH63069.1 - 0.46 10.9 14.0 3.9 7.9 5.8 2.9 1 1 0 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 CCH63069.1 - 0.57 10.6 10.2 1.6 9.1 10.2 1.7 1 1 0 1 1 1 0 Fez1 CLZ PF16526.5 CCH63069.1 - 0.58 10.6 6.5 13 6.2 0.3 3.5 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Wtap PF17098.5 CCH63069.1 - 0.85 9.5 10.2 2.6 7.9 0.4 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family Golgin_A5 PF09787.9 CCH63069.1 - 0.9 9.0 10.8 0.82 9.1 9.8 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 Atg14 PF10186.9 CCH63069.1 - 1.6 7.7 8.3 1.3 8.0 2.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 CCH63069.1 - 2.1 8.8 9.9 1.2 9.6 0.2 3.7 2 2 1 3 3 3 0 Lipoprotein leucine-zipper HIP1_clath_bdg PF16515.5 CCH63069.1 - 3 8.5 12.8 8.6 7.0 2.3 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ALMT PF11744.8 CCH63069.1 - 4.7 5.9 8.4 7 5.4 8.3 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter Uso1_p115_C PF04871.13 CCH63069.1 - 5.2 7.5 9.2 18 5.7 8.2 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 CCH63069.1 - 5.8 6.2 9.0 9.5 5.5 9.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.17 CCH63071.1 - 4.5e-36 125.1 0.2 9.6e-22 78.2 0.0 3.1 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.15 CCH63071.1 - 1.8e-05 24.1 0.1 0.00053 19.3 0.0 2.3 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 CCH63071.1 - 0.014 15.2 0.4 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 Palmitoyl protein thioesterase OLF PF02191.16 CCH63071.1 - 0.11 12.1 2.5 0.14 11.7 0.8 1.9 2 0 0 2 2 2 0 Olfactomedin-like domain RNA_Me_trans PF04252.13 CCH63072.1 - 1.5e-78 263.0 0.0 1.7e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase ATP19 PF11022.8 CCH63073.1 - 2.9e-19 69.2 0.0 3.3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Cpn10 PF00166.21 CCH63074.1 - 6.7e-26 90.2 0.2 7.6e-26 90.0 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit HU-CCDC81_bac_1 PF18174.1 CCH63074.1 - 0.054 13.4 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 TA0956 PF11513.8 CCH63075.1 - 0.48 10.7 7.0 1.5 9.1 0.1 4.1 4 0 0 4 4 4 0 Thermoplasma acidophilum protein TA0956 SIR2 PF02146.17 CCH63076.1 - 9.4e-39 133.1 0.2 1.2e-37 129.5 0.0 2.2 2 0 0 2 2 2 1 Sir2 family FYVE_2 PF02318.16 CCH63076.1 - 0.018 15.2 0.5 0.018 15.2 0.5 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 CCH63076.1 - 0.15 12.2 1.0 0.35 11.0 0.4 1.9 2 0 0 2 2 2 0 Zinc ribbon domain bZIP_1 PF00170.21 CCH63077.1 - 2.5e-11 43.5 9.8 4.4e-11 42.7 9.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor FAM199X PF15814.5 CCH63077.1 - 0.011 14.8 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X HALZ PF02183.18 CCH63077.1 - 0.017 15.3 3.1 0.033 14.4 3.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cellulase PF00150.18 CCH63078.1 - 8.3e-13 48.4 25.3 5.5e-12 45.7 25.3 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) VD10_N PF08476.10 CCH63078.1 - 0.056 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Viral D10 N-terminal Fasciclin PF02469.22 CCH63079.1 - 0.00016 21.9 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain EPV_E5 PF08135.11 CCH63079.1 - 0.098 13.0 1.6 0.17 12.3 1.6 1.3 1 0 0 1 1 1 0 Major transforming protein E5 family VPS11_C PF12451.8 CCH63079.1 - 0.25 11.6 0.0 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal HLH PF00010.26 CCH63080.1 - 1.4e-16 60.1 1.6 2.2e-16 59.5 1.6 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DHHC PF01529.20 CCH63081.1 - 9e-26 90.6 5.4 9e-26 90.6 5.4 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CCH63081.1 - 9.1e-25 86.7 0.1 1.1e-08 35.4 0.2 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCH63081.1 - 9.5e-25 87.0 0.0 8.5e-13 48.7 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCH63081.1 - 1.1e-21 74.5 0.1 0.0011 19.2 0.1 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CCH63081.1 - 4e-19 68.1 0.1 1.1e-05 25.6 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CCH63081.1 - 2.3e-17 62.8 1.2 3.4e-06 27.2 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) UNC45-central PF11701.8 CCH63082.1 - 2.5e-27 95.7 0.2 1.2e-26 93.5 0.2 2.3 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central HAGH_C PF16123.5 CCH63083.1 - 2.4e-16 60.0 0.0 5.9e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CCH63083.1 - 1.7e-11 44.5 0.1 9.9e-11 42.0 0.1 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CCH63083.1 - 2e-05 24.2 0.0 3.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Tom6 PF17112.5 CCH63085.1 - 1.6e-25 88.3 0.1 2.3e-25 87.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal TOM6p PF15184.6 CCH63085.1 - 0.2 11.5 0.3 0.21 11.4 0.2 1.4 1 1 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Pmp3 PF01679.17 CCH63086.1 - 4e-15 55.7 9.2 4.3e-15 55.6 9.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.12 CCH63086.1 - 0.03 14.4 2.9 0.036 14.1 2.9 1.1 1 0 0 1 1 1 0 Chlorhexidine efflux transporter YbhQ PF11076.8 CCH63086.1 - 0.093 12.7 0.6 0.092 12.8 0.6 1.1 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ DEAD PF00270.29 CCH63087.1 - 5e-35 120.8 0.6 1e-34 119.8 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCH63087.1 - 2.3e-29 102.0 0.2 2.4e-28 98.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CCH63087.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCH63087.1 - 0.32 11.2 1.4 1.9 8.7 1.4 2.3 1 1 0 1 1 1 0 AAA domain STD1 PF17235.2 CCH63088.1 - 2.6e-14 53.4 1.7 1e-13 51.4 1.7 1.9 1 1 0 1 1 1 1 STD1/MTH1 Orthopox_F14 PF06076.12 CCH63088.1 - 0.13 12.6 0.3 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 Orthopoxvirus F14 protein RAP PF08373.10 CCH63088.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.2 2 0 0 2 2 2 0 RAP domain Acyltransferase PF01553.21 CCH63089.1 - 3.5e-06 26.7 0.0 7.1e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase DUF2985 PF11204.8 CCH63089.1 - 0.067 13.4 0.0 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF4680 PF15730.5 CCH63089.1 - 0.15 12.4 2.0 0.3 11.4 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Nro1 PF12753.7 CCH63090.1 - 8.3e-124 413.7 25.2 9.4e-124 413.5 25.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Telomere_reg-2 PF10193.9 CCH63090.1 - 0.19 12.2 2.5 11 6.5 0.2 2.9 2 1 0 2 2 2 0 Telomere length regulation protein zf-AN1 PF01428.16 CCH63091.1 - 1.2e-10 41.4 8.0 2e-10 40.6 8.0 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger C5HCH PF17982.1 CCH63091.1 - 0.39 10.9 4.8 0.76 10.0 4.8 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain Flavoprotein PF02441.19 CCH63092.1 - 5.1e-52 175.8 0.0 1.5e-51 174.3 0.0 1.9 1 0 0 1 1 1 1 Flavoprotein SGS PF05002.15 CCH63093.1 - 8.1e-32 109.2 1.8 2.6e-31 107.6 1.8 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CCH63093.1 - 1.3e-11 45.3 1.5 2.7e-11 44.3 1.5 1.6 1 0 0 1 1 1 1 CS domain MAP65_ASE1 PF03999.12 CCH63094.1 - 3.5e-85 286.9 55.5 3.5e-85 286.9 55.5 2.1 2 1 1 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) DnaJ PF00226.31 CCH63095.1 - 5e-18 65.0 0.2 1.7e-17 63.3 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain DUF2121 PF09894.9 CCH63095.1 - 0.12 11.9 5.9 0.14 11.7 1.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) MFS_1 PF07690.16 CCH63096.1 - 1e-24 87.1 14.2 2.4e-24 85.9 14.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 CCH63097.1 - 8.4e-39 133.5 0.0 4.6e-38 131.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCH63097.1 - 5.7e-17 61.9 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CCH63098.1 - 1.9e-38 132.4 0.0 3.6e-25 88.8 0.2 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH63098.1 - 8.7e-20 71.1 0.0 1.7e-15 57.0 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCH63098.1 - 0.014 14.8 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Zip PF02535.22 CCH63099.1 - 1.4e-17 63.9 20.9 5.8e-15 55.3 9.7 3.0 2 2 1 3 3 3 2 ZIP Zinc transporter Presenilin PF01080.17 CCH63099.1 - 1.7 7.3 4.1 2.9 6.6 4.1 1.4 1 0 0 1 1 1 0 Presenilin GST_C PF00043.25 CCH63100.1 - 3.9e-07 30.2 0.0 6e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH63100.1 - 5.2e-05 23.2 0.0 8.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCH63100.1 - 0.098 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCH63101.1 - 2.3e-08 34.1 0.0 3.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCH63101.1 - 0.00088 19.2 0.2 0.0019 18.2 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SRI PF08236.11 CCH63102.1 - 8.6e-21 73.9 6.6 8.6e-21 73.9 6.6 3.0 4 0 0 4 4 4 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CCH63102.1 - 1.9e-18 67.4 0.4 1.9e-18 67.4 0.4 3.9 3 2 0 3 3 3 1 SET domain WW_1 PF18507.1 CCH63102.1 - 2.8e-17 62.1 2.5 6.3e-17 60.9 2.5 1.6 1 0 0 1 1 1 1 WW domain AWS PF17907.1 CCH63102.1 - 9.1e-13 48.0 12.0 9.1e-13 48.0 12.0 2.2 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 CCH63102.1 - 0.00024 21.1 0.1 0.00024 21.1 0.1 3.3 4 0 0 4 4 4 1 TFIIS helical bundle-like domain WW PF00397.26 CCH63102.1 - 0.017 15.2 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 WW domain Glyco_hydro_49N PF17433.2 CCH63102.1 - 0.022 14.4 0.1 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain SUIM_assoc PF16619.5 CCH63102.1 - 0.07 13.2 0.5 0.21 11.7 0.5 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2976 PF11190.8 CCH63103.1 - 0.0046 16.7 0.1 2 8.3 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2976) BPD_transp_1 PF00528.22 CCH63103.1 - 0.03 14.1 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF2401 PF10287.9 CCH63104.1 - 4.4e-73 245.7 1.0 5.6e-73 245.3 1.0 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCH63104.1 - 8.2e-23 80.6 0.1 1.7e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) STE3 PF02076.15 CCH63105.1 - 8.5e-87 291.0 27.5 1.1e-86 290.7 27.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor KRE9 PF05390.11 CCH63106.1 - 3.6e-46 156.1 4.6 3.6e-46 156.1 4.6 2.3 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCH63106.1 - 2.9e-10 40.8 0.3 2.9e-10 40.8 0.3 2.6 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SWIRM PF04433.17 CCH63107.1 - 8.2e-27 93.4 0.1 2.4e-26 91.9 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 CCH63107.1 - 6.3e-14 51.9 0.7 6.3e-14 51.9 0.7 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CCH63107.1 - 3.8e-13 49.2 0.8 9.3e-13 47.9 0.8 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 CCH63107.1 - 2.4e-09 37.3 0.1 1.2e-08 35.1 0.1 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CCH63107.1 - 0.0048 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 ATG27 PF09451.10 CCH63108.1 - 1.1e-19 71.4 3.9 1.3e-19 71.1 3.9 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 SUIM_assoc PF16619.5 CCH63108.1 - 0.011 15.8 1.0 0.011 15.8 1.0 1.9 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Prefoldin_2 PF01920.20 CCH63110.1 - 2.1e-18 66.2 9.9 2.8e-18 65.8 9.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1699 PF08004.11 CCH63110.1 - 0.0059 16.3 0.2 0.023 14.4 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1699) YL1 PF05764.13 CCH63110.1 - 0.13 12.4 4.9 0.15 12.1 4.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RasGAP_C PF03836.15 CCH63110.1 - 0.38 10.9 9.5 2.2 8.4 3.2 2.2 2 0 0 2 2 2 0 RasGAP C-terminus DUF5320 PF17253.2 CCH63110.1 - 0.41 11.7 1.7 1.2 10.2 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) APG6_N PF17675.1 CCH63110.1 - 0.81 10.2 11.3 4 8.0 11.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 CCH63110.1 - 1.5 8.6 11.8 4.4 7.2 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 CCH63110.1 - 7.1 5.9 13.0 37 3.5 13.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FlxA PF14282.6 CCH63110.1 - 8.3 6.5 19.7 4.4 7.3 0.2 2.5 2 1 0 2 2 2 0 FlxA-like protein ATP12 PF07542.11 CCH63111.1 - 7.3e-27 94.0 0.0 1.6e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_transf_34 PF05637.12 CCH63113.1 - 8.9e-29 100.9 4.2 1.2e-28 100.4 4.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Gon7 PF08738.10 CCH63114.1 - 7.4e-43 145.0 0.2 9e-43 144.8 0.2 1.1 1 0 0 1 1 1 1 Gon7 family muHD PF10291.9 CCH63115.1 - 9.4e-64 215.4 0.1 1.5e-63 214.7 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mannosyl_trans3 PF11051.8 CCH63116.1 - 1.1e-72 244.7 0.0 1.9e-72 243.9 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.25 CCH63117.1 - 2.8e-44 151.5 1.4 4.2e-42 144.3 0.2 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCH63117.1 - 4.4e-26 91.7 0.0 7.8e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S11 PF00411.19 CCH63118.1 - 3.1e-46 156.3 1.8 4.2e-46 155.9 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CCH63118.1 - 0.052 12.9 0.4 0.063 12.6 0.4 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Myb_DNA-binding PF00249.31 CCH63119.1 - 1.2e-14 54.2 0.0 1.2e-06 28.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCH63119.1 - 4.3e-07 30.1 1.7 0.0028 17.9 0.2 3.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CCH63119.1 - 9.1e-06 25.5 0.2 9.1e-06 25.5 0.2 3.6 3 0 0 3 3 3 1 Myb DNA-binding like ELO PF01151.18 CCH63120.1 - 3.2e-57 193.9 22.3 4.1e-57 193.6 22.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.21 CCH63121.1 - 2.5e-18 66.8 0.0 6.9e-18 65.4 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 zf-CCHC PF00098.23 CCH63122.1 - 9.6e-08 31.8 26.3 8e-05 22.5 2.3 4.9 5 1 0 5 5 5 3 Zinc knuckle zf-C2H2_10 PF16588.5 CCH63122.1 - 0.00046 19.8 1.1 0.00046 19.8 1.1 4.7 4 1 1 5 5 5 2 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CCH63122.1 - 0.0042 16.9 3.0 0.0042 16.9 3.0 4.1 4 0 0 4 4 4 3 Zinc knuckle tRNA-synt_2b PF00587.25 CCH63123.1 - 5.5e-36 124.2 0.0 1e-35 123.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCH63123.1 - 3.9e-19 68.6 0.5 9.7e-19 67.3 0.5 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CCH63123.1 - 2.8e-13 49.7 0.0 5.8e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CCH63123.1 - 8.7e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain ROF PF07073.12 CCH63123.1 - 0.13 12.4 0.0 30 4.8 0.0 2.6 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) GET2 PF08690.10 CCH63124.1 - 1.7e-87 294.0 0.0 1.9e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 GTP1_OBG PF01018.22 CCH63124.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 GTP1/OBG BING4CT PF08149.11 CCH63125.1 - 2.5e-35 120.1 0.7 4.3e-33 112.9 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 CCH63125.1 - 5.3e-07 30.2 0.4 0.0006 20.6 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCH63125.1 - 7.7e-06 26.1 0.0 6.4 7.1 0.0 4.8 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain GLYCAM-1 PF05242.11 CCH63125.1 - 4.8 7.3 8.8 1.1 9.4 3.1 2.4 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) SPO22 PF08631.10 CCH63126.1 - 2.7e-59 200.9 17.7 6.3e-59 199.7 1.5 4.2 4 2 1 5 5 5 2 Meiosis protein SPO22/ZIP4 like PIR PF00399.19 CCH63127.1 - 2.7e-22 77.7 47.1 3e-08 33.0 5.8 7.0 7 0 0 7 7 7 4 Yeast PIR protein repeat TFIIA PF03153.13 CCH63127.1 - 2.3 8.1 20.7 3.8 7.4 20.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HORMA PF02301.18 CCH63128.1 - 8.1e-60 202.0 1.4 1.7e-59 201.0 1.4 1.5 1 0 0 1 1 1 1 HORMA domain Dpoe2NT PF12213.8 CCH63128.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal PHD_2 PF13831.6 CCH63128.1 - 3.8 7.1 6.3 12 5.6 6.3 1.8 1 0 0 1 1 1 0 PHD-finger Yos1 PF08571.10 CCH63129.1 - 8.3e-32 109.3 2.1 9.3e-32 109.1 2.1 1.0 1 0 0 1 1 1 1 Yos1-like DUF3671 PF12420.8 CCH63129.1 - 0.048 13.7 0.4 0.064 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function ArsC PF03960.15 CCH63129.1 - 0.059 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 ArsC family LCCL PF03815.19 CCH63130.1 - 1.5e-07 31.4 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Ribonuc_red_lgC PF02867.15 CCH63131.1 - 1.4e-182 607.9 0.0 1.8e-182 607.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCH63131.1 - 4.7e-22 77.8 0.0 1.3e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCH63131.1 - 2e-16 60.3 0.0 8.9e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NAT PF04768.13 CCH63132.1 - 1.5e-40 138.7 0.3 4.2e-40 137.2 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 CCH63132.1 - 7.1e-17 61.8 0.0 9.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family zf-RING_4 PF14570.6 CCH63133.1 - 2.7e-20 71.9 12.9 5e-20 71.0 12.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CCH63133.1 - 2.1e-07 30.7 8.2 4.4e-07 29.7 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CCH63133.1 - 1.4e-06 28.0 0.1 0.002 17.9 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 CCH63133.1 - 0.00013 21.9 3.7 0.00013 21.9 3.7 2.4 2 1 0 2 2 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 CCH63133.1 - 0.00013 22.2 9.5 0.00025 21.3 9.5 1.5 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 CCH63133.1 - 0.0002 21.0 0.1 0.0034 17.0 0.1 2.4 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CCH63133.1 - 0.00031 20.5 6.8 0.0098 15.7 7.6 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CCH63133.1 - 0.00046 19.6 3.2 0.00046 19.6 3.2 4.4 4 1 0 4 4 3 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 CCH63133.1 - 0.0015 18.3 10.6 0.0036 17.2 10.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCH63133.1 - 0.11 12.5 9.2 0.43 10.7 9.2 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCH63133.1 - 0.24 11.4 10.0 0.61 10.1 10.0 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCH63133.1 - 0.64 9.9 9.2 1.4 8.8 9.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RGI1 PF10843.8 CCH63134.1 - 4.2e-30 104.9 15.5 7e-30 104.1 15.5 1.3 1 1 0 1 1 1 1 Respiratory growth induced protein 1 HEPN_RiboL-PSP PF18735.1 CCH63134.1 - 0.019 14.9 4.9 0.025 14.5 4.9 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN FRQ PF09421.10 CCH63134.1 - 0.033 12.3 0.7 0.04 12.0 0.7 1.0 1 0 0 1 1 1 0 Frequency clock protein Mrx7 PF10906.8 CCH63134.1 - 0.75 10.1 7.3 0.55 10.5 3.4 2.7 1 1 1 2 2 2 0 MIOREX complex component 7 Tho1_MOS11_C PF18592.1 CCH63135.1 - 2e-23 81.9 0.5 4.5e-23 80.8 0.5 1.6 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 CCH63135.1 - 5.9e-13 48.2 0.0 1.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain DUF3450 PF11932.8 CCH63135.1 - 0.088 12.1 3.8 0.13 11.6 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 CCH63135.1 - 0.38 10.0 1.8 0.56 9.4 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein ASD2 PF08687.11 CCH63135.1 - 0.77 9.3 12.4 0.14 11.7 8.6 1.7 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 HAD_2 PF13419.6 CCH63137.1 - 8.1e-16 58.6 0.0 1e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCH63137.1 - 3.6e-09 37.2 0.0 5.2e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCH63137.1 - 0.0027 18.1 0.0 0.0037 17.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCH63137.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribonuc_L-PSP PF01042.21 CCH63138.1 - 1.4e-38 131.6 0.1 1.6e-38 131.4 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_L34e PF01199.18 CCH63139.1 - 6.6e-44 148.1 5.9 6.6e-44 148.1 5.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e Steroid_dh PF02544.16 CCH63140.1 - 3.4e-09 36.8 10.8 5.1e-09 36.3 9.2 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1385 PF07136.11 CCH63141.1 - 0.0096 15.2 1.7 0.073 12.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1385) PhoLip_ATPase_C PF16212.5 CCH63142.1 - 4e-50 170.9 18.1 4e-50 170.9 18.1 2.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCH63142.1 - 2.1e-18 65.7 1.8 8.9e-18 63.8 1.8 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCH63142.1 - 4e-12 46.0 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCH63142.1 - 1.2e-11 45.3 0.9 1.9e-06 28.4 0.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCH63142.1 - 8.5e-10 38.6 0.0 1.2e-08 34.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCH63142.1 - 0.0045 16.8 0.1 0.039 13.7 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EXS PF03124.14 CCH63143.1 - 3e-83 279.9 26.9 4.3e-83 279.4 26.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CCH63143.1 - 9.7e-21 75.1 19.8 1.8e-11 44.6 1.4 3.9 3 1 0 3 3 3 2 SPX domain CBM_21 PF03370.13 CCH63144.1 - 4.6e-26 91.2 1.8 1.2e-25 89.9 1.8 1.7 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCH63144.1 - 1.9e-09 38.0 1.2 6.7e-09 36.2 1.2 2.0 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) bZIP_2 PF07716.15 CCH63145.1 - 7e-06 26.0 11.1 2.4e-05 24.3 11.2 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CCH63145.1 - 0.21 11.7 8.8 0.37 10.9 8.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor Tim44 PF04280.15 CCH63146.1 - 1.5e-34 119.2 0.2 3.7e-34 117.9 0.0 1.8 2 0 0 2 2 2 1 Tim44-like domain RGS-like PF09128.11 CCH63146.1 - 0.042 13.6 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain MscS_porin PF12795.7 CCH63146.1 - 1.7 8.2 8.8 2.9 7.4 8.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain RNA_pol_A_bac PF01000.26 CCH63148.1 - 9.9e-32 109.6 0.3 3.4e-31 107.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCH63148.1 - 8.9e-17 60.3 0.0 1.2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GRP PF07172.11 CCH63148.1 - 0.11 13.1 8.4 0.19 12.5 8.4 1.3 1 0 0 1 1 1 0 Glycine rich protein family His_biosynth PF00977.21 CCH63149.1 - 3.4e-19 69.2 0.1 4.3e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Flagellar_put PF12611.8 CCH63149.1 - 0.068 13.0 1.0 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 Putative flagellar X PF00739.19 CCH63150.1 - 0.2 11.8 0.0 0.53 10.4 0.0 1.7 1 1 0 1 1 1 0 Trans-activation protein X HLH PF00010.26 CCH63151.1 - 1.2e-11 44.4 0.1 3.2e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UCR_hinge PF02320.16 CCH63152.1 - 4.6e-25 87.6 6.7 6.8e-25 87.1 6.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Nop14 PF04147.12 CCH63152.1 - 0.0013 17.1 23.8 0.0015 16.9 23.8 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 CCH63152.1 - 0.0028 16.1 16.2 0.003 15.9 16.2 1.0 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 CCH63152.1 - 0.0082 14.3 33.9 0.0087 14.2 33.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi Sigma70_ner PF04546.13 CCH63152.1 - 0.019 14.9 18.0 0.028 14.3 18.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop53 PF07767.11 CCH63152.1 - 0.039 13.4 8.3 0.054 12.9 8.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mpp10 PF04006.12 CCH63152.1 - 0.09 11.2 21.2 0.11 11.0 21.2 1.0 1 0 0 1 1 1 0 Mpp10 protein YL1 PF05764.13 CCH63152.1 - 0.13 12.4 26.8 0.15 12.1 26.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 CCH63152.1 - 0.13 10.8 19.7 0.13 10.7 19.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PDDEXK_6 PF04720.12 CCH63152.1 - 0.2 11.5 5.9 0.25 11.3 5.9 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function RPN2_C PF18004.1 CCH63152.1 - 0.23 11.4 9.1 0.38 10.7 9.1 1.4 1 1 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF1115 PF06544.12 CCH63152.1 - 0.38 10.8 4.1 0.51 10.4 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF2796 PF10986.8 CCH63152.1 - 1.2 9.1 11.6 1.5 8.7 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SDA1 PF05285.12 CCH63152.1 - 2.2 7.6 27.3 2.6 7.4 27.3 1.1 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.7 CCH63152.1 - 2.4 7.9 9.6 2.9 7.7 9.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 CCH63152.1 - 4.1 6.1 9.2 4.3 6.0 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CNDH2_C PF16858.5 CCH63152.1 - 8.8 6.1 17.0 10 5.9 17.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CobT PF06213.12 CCH63152.1 - 9 5.6 22.1 12 5.2 22.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RRM_1 PF00076.22 CCH63153.1 - 8.2e-15 54.4 0.1 7.1e-09 35.4 0.1 3.4 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3BGR PF04908.15 CCH63153.1 - 0.021 15.0 1.9 0.065 13.4 1.9 1.9 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ribosomal_L2_C PF03947.18 CCH63154.1 - 3.4e-44 150.1 3.9 5.8e-44 149.3 3.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCH63154.1 - 1.1e-14 54.2 0.2 2.9e-14 52.8 0.2 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HEAT PF02985.22 CCH63155.1 - 0.13 12.6 0.0 1.2 9.6 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat LktC PF06261.11 CCH63155.1 - 0.36 10.7 5.3 0.11 12.4 1.3 2.3 2 0 0 2 2 2 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Steroid_dh PF02544.16 CCH63156.1 - 0.041 13.9 0.1 0.055 13.4 0.1 1.2 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2680 PF10925.8 CCH63156.1 - 0.076 13.0 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Xrn1_D3 PF18194.1 CCH63157.1 - 0.063 13.4 0.8 0.2 11.8 0.8 1.9 1 0 0 1 1 1 0 Exoribonuclease 1 Domain-3 Sedlin_N PF04628.13 CCH63158.1 - 3e-32 111.5 0.0 4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CCH63158.1 - 8.4e-05 22.5 0.1 0.00026 21.0 0.0 1.8 2 0 0 2 2 2 1 Sybindin-like family Med22 PF06179.12 CCH63159.1 - 5.2e-19 68.4 5.9 1e-18 67.4 5.9 1.5 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex dUTPase PF00692.19 CCH63160.1 - 8.8e-46 154.8 0.0 1e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase Ribosomal_S5_C PF03719.15 CCH63161.1 - 7.3e-24 83.0 0.0 1.3e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CCH63161.1 - 5.4e-20 71.1 0.1 8.5e-20 70.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain HMG_box PF00505.19 CCH63162.1 - 2.2e-13 50.4 4.7 8.6e-13 48.5 4.7 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCH63162.1 - 0.00012 22.6 2.5 0.00046 20.7 1.2 2.3 1 1 1 2 2 2 1 HMG-box domain Amino_oxidase PF01593.24 CCH63163.1 - 4.6e-18 65.7 0.1 6e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCH63163.1 - 3e-11 43.4 0.0 1e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.15 CCH63163.1 - 0.0016 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.27 CCH63163.1 - 0.019 15.5 0.0 0.3 11.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCH63163.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 CCH63163.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCH63163.1 - 0.11 11.6 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lact-deh-memb PF09330.11 CCH63163.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Gti1_Pac2 PF09729.9 CCH63164.1 - 3.3e-44 151.1 1.4 6e-41 140.5 0.0 3.7 2 2 1 3 3 3 2 Gti1/Pac2 family Thioredoxin PF00085.20 CCH63165.1 - 5.1e-21 74.6 3.8 4.9e-19 68.2 0.1 3.9 6 0 0 6 6 6 2 Thioredoxin Herpes_UL14 PF03580.14 CCH63166.1 - 0.029 14.6 1.2 0.029 14.6 1.2 2.3 3 0 0 3 3 3 0 Herpesvirus UL14-like protein Prefoldin_2 PF01920.20 CCH63167.1 - 8.6e-21 73.9 10.2 1.1e-20 73.6 10.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit CLZ PF16526.5 CCH63167.1 - 0.035 14.5 2.7 1.3 9.5 0.3 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATP_bind_3 PF01171.20 CCH63167.1 - 0.049 13.4 0.2 0.06 13.1 0.2 1.1 1 0 0 1 1 1 0 PP-loop family Prefoldin PF02996.17 CCH63167.1 - 0.066 13.1 5.0 0.4 10.6 0.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF5603 PF18231.1 CCH63167.1 - 0.15 12.4 2.2 1.1 9.6 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5603) SlyX PF04102.12 CCH63167.1 - 0.25 12.0 3.3 6.4 7.5 0.3 2.1 2 0 0 2 2 2 0 SlyX Spc24 PF08286.11 CCH63167.1 - 0.29 11.4 8.0 1.2 9.4 1.3 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DDOST_48kD PF03345.14 CCH63168.1 - 1.2e-116 390.0 0.8 1.5e-116 389.7 0.8 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Viral_P18 PF04521.13 CCH63169.1 - 0.016 15.0 0.1 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Laminin_II PF06009.12 CCH63169.1 - 0.077 13.0 0.5 0.088 12.8 0.5 1.1 1 0 0 1 1 1 0 Laminin Domain II ThrE PF06738.12 CCH63169.1 - 0.24 10.8 0.1 0.27 10.6 0.1 1.1 1 0 0 1 1 1 0 Putative threonine/serine exporter GET2 PF08690.10 CCH63169.1 - 0.66 9.6 4.6 0.67 9.6 4.6 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 Syja_N PF02383.18 CCH63170.1 - 1.3e-51 175.8 1.3 5.7e-51 173.7 0.3 2.1 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 CCH63170.1 - 1.7e-10 40.8 0.1 4.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.31 CCH63171.1 - 2.2e-19 69.7 1.7 9.5e-14 51.6 0.2 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 CCH63171.1 - 7.2e-06 26.5 0.0 2.3e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CCH63171.1 - 7.4e-06 26.2 0.3 0.0018 18.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CCH63171.1 - 1.4e-05 25.2 0.1 0.0047 17.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCH63171.1 - 1.7e-05 25.3 0.1 0.00016 22.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCH63171.1 - 0.00022 21.4 0.6 0.044 14.3 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat DUF3342 PF11822.8 CCH63171.1 - 0.028 14.6 0.5 0.096 12.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) SRP1_TIP1 PF00660.17 CCH63173.1 - 2.6e-37 126.9 0.8 5.8e-37 125.8 0.8 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family SRP1_TIP1 PF00660.17 CCH63174.1 - 8.2e-35 118.8 0.2 1.1e-34 118.4 0.2 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family SRP1_TIP1 PF00660.17 CCH63175.1 - 2.9e-25 88.2 1.0 2.9e-25 88.2 1.0 4.0 2 1 1 4 4 4 1 Seripauperin and TIP1 family EF-hand_4 PF12763.7 CCH63176.1 - 2.5e-23 82.0 0.5 2.6e-12 46.6 0.0 3.2 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCH63176.1 - 5.6e-09 36.3 0.0 8.5e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CCH63176.1 - 1.2e-08 33.9 0.0 0.0029 17.0 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CCH63176.1 - 8e-06 25.4 0.0 0.088 12.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain DUF1720 PF08226.11 CCH63176.1 - 3.8e-05 24.0 27.4 3.8e-05 24.0 27.4 9.1 3 3 3 6 6 6 3 Domain of unknown function (DUF1720) EF-hand_8 PF13833.6 CCH63176.1 - 0.0037 17.1 0.0 0.99 9.3 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair RRM_1 PF00076.22 CCH63177.1 - 1.5e-18 66.4 0.5 3.3e-18 65.3 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCH63177.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 CCH63177.1 - 0.019 14.5 0.2 0.041 13.5 0.1 1.6 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CCH63177.1 - 0.042 13.7 0.1 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif PIR PF00399.19 CCH63178.1 - 1e-05 24.9 4.0 1e-05 24.9 4.0 5.4 7 0 0 7 7 7 1 Yeast PIR protein repeat zf-FCS PF06467.14 CCH63178.1 - 2.6 8.1 15.1 17 5.4 0.0 4.9 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif zf-NADH-PPase PF09297.11 CCH63178.1 - 5.3 6.8 21.2 16 5.3 0.7 4.5 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain SRP1_TIP1 PF00660.17 CCH63179.1 - 9.2e-35 118.7 0.2 1.6e-34 117.9 0.2 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family Cornifin PF02389.15 CCH63179.1 - 2.6e-06 27.7 0.5 3.8e-06 27.1 0.5 1.2 1 0 0 1 1 1 1 Cornifin (SPRR) family SOBP PF15279.6 CCH63179.1 - 0.22 12.1 6.6 0.34 11.5 6.3 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein GEMIN8 PF15348.6 CCH63179.1 - 0.35 11.1 3.7 0.57 10.5 3.7 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 UPF0688 PF15772.5 CCH63179.1 - 1.1 9.5 14.2 1.9 8.7 14.2 1.3 1 0 0 1 1 1 0 UPF0688 family GCOM2 PF15328.6 CCH63179.1 - 1.8 8.9 10.0 2.6 8.3 10.0 1.2 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Mucin PF01456.17 CCH63179.1 - 2.5 8.1 20.0 4.5 7.3 20.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RAP1 PF07218.11 CCH63179.1 - 8.5 4.5 11.2 11 4.1 11.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SRP1_TIP1 PF00660.17 CCH63180.1 - 1.4e-24 86.0 0.8 1.4e-24 86.0 0.8 3.3 4 1 0 4 4 4 1 Seripauperin and TIP1 family EF-hand_4 PF12763.7 CCH63181.1 - 6.3e-29 100.0 0.0 1e-13 51.1 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CCH63181.1 - 8.8e-09 34.3 0.0 0.0041 16.6 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CCH63181.1 - 1.1e-08 35.4 0.0 0.00034 21.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF1720 PF08226.11 CCH63181.1 - 4.3e-07 30.2 66.0 3.7e-05 24.1 27.1 12.7 5 2 7 12 12 12 6 Domain of unknown function (DUF1720) EF-hand_6 PF13405.6 CCH63181.1 - 2.2e-06 27.1 0.0 0.32 11.0 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CCH63181.1 - 0.00011 22.0 0.0 0.28 11.1 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair Cwf_Cwc_15 PF04889.12 CCH63181.1 - 0.0017 18.2 16.6 0.0017 18.2 16.6 4.2 5 0 0 5 5 5 1 Cwf15/Cwc15 cell cycle control protein E3_binding PF02817.17 CCH63181.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 e3 binding domain SRP1_TIP1 PF00660.17 CCH63182.1 - 1.3e-27 95.8 0.4 1.3e-27 95.8 0.4 1.6 2 0 0 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.19 CCH63182.1 - 5.5e-06 25.8 7.0 5.5e-06 25.8 7.0 3.1 2 0 0 2 2 2 1 Yeast PIR protein repeat XRN_M PF17846.1 CCH63182.1 - 0.015 14.3 2.3 0.019 13.9 2.3 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 CCH63182.1 - 0.63 8.7 13.8 0.79 8.4 13.8 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CCH63182.1 - 0.64 10.0 6.9 0.8 9.7 6.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SRP-alpha_N PF04086.13 CCH63182.1 - 0.76 9.6 16.5 0.92 9.4 16.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mitofilin PF09731.9 CCH63182.1 - 0.79 8.5 18.7 1 8.1 18.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SAPS PF04499.15 CCH63182.1 - 1.1 8.0 8.4 1.1 8.0 8.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 CCH63182.1 - 1.1 6.3 11.4 1 6.4 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5427 PF10310.9 CCH63182.1 - 1.1 8.1 19.2 1.3 7.9 19.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Zip PF02535.22 CCH63182.1 - 2.4 7.3 7.6 3.1 6.9 7.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TP53IP5 PF15331.6 CCH63182.1 - 2.7 8.1 12.7 3.6 7.7 12.7 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SOBP PF15279.6 CCH63182.1 - 2.7 8.5 14.0 3.4 8.2 14.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.9 CCH63182.1 - 3 6.3 15.0 3.6 6.0 15.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF913 PF06025.12 CCH63182.1 - 4.2 6.2 10.7 5.7 5.8 10.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.7 CCH63182.1 - 4.4 5.3 15.9 5.2 5.1 15.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 CCH63182.1 - 4.8 5.7 14.3 5.5 5.5 14.3 1.1 1 0 0 1 1 1 0 Hamartin protein SKA1 PF07160.12 CCH63182.1 - 5.3 6.8 16.6 6.7 6.5 0.0 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 SLC12 PF03522.15 CCH63182.1 - 5.4 5.9 13.1 6.7 5.6 13.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Paramyxo_ncap PF00973.19 CCH63182.1 - 6.8 5.5 10.5 9.4 5.0 10.5 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ASD2 PF08687.11 CCH63182.1 - 9.5 5.7 10.8 14 5.2 10.8 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 DnaJ-X PF14308.6 CCH63183.1 - 4.6e-69 232.1 8.1 4.6e-69 232.1 8.1 2.8 2 1 1 3 3 3 2 X-domain of DnaJ-containing DnaJ PF00226.31 CCH63183.1 - 2e-26 91.9 1.6 5.9e-26 90.4 1.6 1.9 1 0 0 1 1 1 1 DnaJ domain Condensin2nSMC PF12422.8 CCH63183.1 - 0.03 14.5 0.6 0.093 12.9 0.2 2.0 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Presenilin PF01080.17 CCH63183.1 - 0.82 8.4 10.0 1.6 7.4 10.0 1.5 1 0 0 1 1 1 0 Presenilin DUF2149 PF09919.9 CCH63183.1 - 1.7 8.9 5.5 8.2 6.8 0.9 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Aim21 PF11489.8 CCH63184.1 - 5.9e-17 61.9 52.6 5.9e-17 61.9 52.6 4.6 2 1 2 4 4 4 1 Altered inheritance of mitochondria protein 21 Caskin-Pro-rich PF16907.5 CCH63184.1 - 0.0036 17.8 0.8 0.0036 17.8 0.8 3.1 3 0 0 3 3 3 1 Proline rich region of Caskin proteins Sec3-PIP2_bind PF15277.6 CCH63185.1 - 8.7e-21 73.9 1.3 8.7e-21 73.9 1.3 2.9 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 CCH63186.1 - 3.5e-136 455.4 29.3 3.5e-136 455.4 29.3 2.9 2 1 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CCH63186.1 - 1.5e-23 82.8 0.1 6e-23 80.8 0.1 2.2 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF3673 PF12425.8 CCH63186.1 - 0.081 12.9 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) ResIII PF04851.15 CCH63187.1 - 1.3e-20 74.1 0.3 8.5e-20 71.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCH63187.1 - 3.7e-20 72.3 1.0 3.4e-19 69.2 0.3 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCH63187.1 - 9.3e-17 61.3 0.0 4e-16 59.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 CCH63187.1 - 0.00046 19.0 0.0 0.00093 18.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.16 CCH63187.1 - 0.024 14.1 0.0 0.074 12.5 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein Sigma70_r1_2 PF00140.20 CCH63187.1 - 0.072 13.1 1.4 0.15 12.1 1.4 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 GAGA_bind PF06217.12 CCH63187.1 - 0.44 10.8 15.2 0.06 13.6 7.7 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family Mucin PF01456.17 CCH63187.1 - 4.5 7.3 12.0 9.5 6.2 12.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein bZIP_1 PF00170.21 CCH63188.1 - 0.00019 21.4 9.9 0.00019 21.4 9.9 3.1 2 1 1 3 3 3 2 bZIP transcription factor SlyX PF04102.12 CCH63188.1 - 0.19 12.3 1.0 1.4 9.6 0.1 2.6 1 1 1 2 2 2 0 SlyX UPF0242 PF06785.11 CCH63188.1 - 2.4 8.2 23.1 0.13 12.3 11.4 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LETM1 PF07766.13 CCH63189.1 - 1.3e-81 273.9 11.1 1.7e-81 273.5 11.1 1.2 1 0 0 1 1 1 1 LETM1-like protein DUF3674 PF12426.8 CCH63189.1 - 0.11 12.6 0.1 0.28 11.2 0.1 1.6 1 0 0 1 1 1 0 RNA dependent RNA polymerase Fibrinogen_BP PF08017.11 CCH63189.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen binding protein DUF1746 PF08508.10 CCH63190.1 - 0.0021 18.4 5.8 0.0036 17.6 5.8 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Dimerisation PF08100.11 CCH63190.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Rpr2 PF04032.16 CCH63191.1 - 8.1e-21 74.1 3.3 1e-20 73.8 3.3 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Proteasome PF00227.26 CCH63192.1 - 2.4e-56 190.2 0.0 3.2e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCH63192.1 - 1.6e-13 50.1 0.3 5.9e-13 48.2 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YqzE PF14038.6 CCH63192.1 - 0.029 14.4 2.6 0.057 13.4 2.6 1.5 1 0 0 1 1 1 0 YqzE-like protein Snapin_Pallidin PF14712.6 CCH63193.1 - 2.1e-07 31.2 5.6 2.6e-07 31.0 5.6 1.1 1 0 0 1 1 1 1 Snapin/Pallidin DHR10 PF18595.1 CCH63193.1 - 0.0068 16.4 2.5 0.0085 16.1 2.5 1.1 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Allexi_40kDa PF05549.11 CCH63193.1 - 0.014 14.9 1.4 0.015 14.8 1.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein SKA2 PF16740.5 CCH63193.1 - 0.52 10.1 4.4 3.1 7.6 5.1 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 CCH63193.1 - 0.66 10.2 5.6 0.87 9.8 5.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TssO PF17561.2 CCH63193.1 - 0.73 9.9 8.7 11 6.1 9.0 1.9 1 1 0 1 1 1 0 Type VI secretion system, TssO OST3_OST6 PF04756.13 CCH63194.1 - 4.8e-48 164.0 13.3 6.3e-48 163.6 13.3 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF5455 PF17537.2 CCH63194.1 - 0.063 13.7 0.4 0.063 13.7 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5455) EF-hand_4 PF12763.7 CCH63195.1 - 2.6e-44 149.4 2.2 2.6e-44 149.4 2.2 2.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 CCH63195.1 - 6.7e-23 81.9 7.5 3.3e-12 47.0 0.2 2.8 2 1 0 3 3 3 2 Actin cytoskeleton-regulatory complex protein END3 MNE1 PF13762.6 CCH63195.1 - 0.0036 17.3 1.1 0.0095 15.9 1.1 1.7 1 0 0 1 1 1 1 Mitochondrial splicing apparatus component EF-hand_1 PF00036.32 CCH63195.1 - 0.0066 15.9 2.0 0.021 14.4 1.1 2.4 3 0 0 3 3 3 1 EF hand ATG16 PF08614.11 CCH63195.1 - 0.042 14.1 4.0 0.099 12.9 2.3 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.11 CCH63195.1 - 0.089 12.9 2.3 1.5 8.9 0.3 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 He_PIG PF05345.12 CCH63196.1 - 5.6e-12 45.7 4.7 7e-05 22.9 0.1 4.8 4 0 0 4 4 4 4 Putative Ig domain SKG6 PF08693.10 CCH63196.1 - 1.1e-10 40.7 0.3 1.1e-10 40.7 0.3 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mito_carr PF00153.27 CCH63197.1 - 7.1e-63 208.6 2.3 1.2e-21 76.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CCH63197.1 - 2.3e-13 50.4 9.7 3.5e-10 40.2 2.6 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCH63197.1 - 6.5e-12 44.1 8.0 8.7e-05 21.8 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CCH63197.1 - 2.7e-11 42.4 9.5 0.0079 16.0 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CCH63197.1 - 1.7e-06 27.2 9.4 0.005 16.3 0.3 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CCH63197.1 - 2.8e-06 27.1 1.1 0.073 12.9 0.6 2.9 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CCH63197.1 - 0.00066 20.0 0.4 0.3 11.4 0.2 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF2177 PF09945.9 CCH63197.1 - 0.12 12.4 0.1 0.43 10.7 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) HORMA PF02301.18 CCH63198.1 - 2.3e-12 46.9 0.4 5.8e-12 45.7 0.4 1.7 1 1 0 1 1 1 1 HORMA domain Glyco_transf_17 PF04724.13 CCH63198.1 - 0.024 13.7 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 17 MutL_C PF08676.11 CCH63199.1 - 3.8e-25 88.4 0.1 2.2e-24 85.9 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CCH63199.1 - 2.9e-24 85.0 0.8 1.4e-23 82.9 0.2 2.3 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCH63199.1 - 2.9e-11 43.3 0.1 1e-10 41.5 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCH63199.1 - 3.2e-06 27.6 0.8 1.2e-05 25.8 0.1 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PIN_9 PF18477.1 CCH63199.1 - 0.03 14.6 1.5 0.096 13.0 1.5 1.9 1 0 0 1 1 1 0 PIN like domain EOS1 PF12326.8 CCH63200.1 - 7.4e-60 201.8 11.9 7.4e-60 201.8 11.9 1.6 2 0 0 2 2 2 1 N-glycosylation protein DUF4834 PF16118.5 CCH63200.1 - 1.8 9.6 6.7 0.3 12.1 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1214 PF06742.11 CCH63201.1 - 4e-09 36.9 24.6 30 5.1 0.0 10.8 11 1 0 11 11 11 8 Protein of unknown function (DUF1214) Ribosomal_S21e PF01249.18 CCH63201.1 - 1.7e-08 34.4 11.7 63 3.8 0.0 9.2 8 1 1 9 9 9 0 Ribosomal protein S21e Rieske_2 PF13806.6 CCH63201.1 - 0.038 13.9 4.1 90 3.1 0.1 4.7 4 0 0 4 4 4 0 Rieske-like [2Fe-2S] domain Glutenin_hmw PF03157.13 CCH63201.1 - 1.2 7.5 70.9 2.6 6.4 38.4 1.9 1 1 1 2 2 2 0 High molecular weight glutenin subunit # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tetrapisispora_blattae_CBS_6284-ASM31591v1/GCA_000315915.1_ASM31591v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tetrapisispora_blattae_CBS_6284-ASM31591v1/GCA_000315915.1_ASM31591v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tetrapisispora_blattae_CBS_6284-ASM31591v1/GCA_000315915.1_ASM31591v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Tetrapisispora_blattae_CBS_6284-ASM31591v1/GCA_000315915.1_ASM31591v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 06:31:45 2019 # [ok]