# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SNAP PF14938.1 CCH57813.1 - 2 7.4 33.0 1.6 7.8 0.2 8.7 10 0 0 10 10 10 0 Soluble NSF attachment protein, SNAP DUF1771 PF08590.5 CCH57813.1 - 2.7 8.0 18.4 2.2e+02 1.9 0.1 9.9 9 0 0 9 9 9 0 Domain of unknown function (DUF1771) Rad51 PF08423.6 CCH57814.1 - 2.6e-22 78.9 0.1 1.9e-19 69.6 0.0 2.7 3 0 0 3 3 3 2 Rad51 AAA_25 PF13481.1 CCH57814.1 - 4.3e-09 36.0 0.0 1.1e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCH57814.1 - 2.2e-06 26.9 1.1 5.3e-06 25.7 0.2 2.1 2 1 0 2 2 2 1 KaiC RecA PF00154.16 CCH57814.1 - 5.4e-05 22.3 0.0 0.00011 21.4 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DUF4263 PF14082.1 CCH57814.1 - 0.0023 17.9 3.0 0.0054 16.6 2.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4263) T2SE PF00437.15 CCH57814.1 - 0.028 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3571 PF12095.3 CCH57814.1 - 0.055 13.7 0.3 0.17 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF972 PF06156.8 CCH57814.1 - 1 9.7 5.2 0.53 10.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) RCR PF12273.3 CCH57815.1 - 1.7e-32 112.7 0.5 1.7e-32 112.7 0.4 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF3328 PF11807.3 CCH57815.1 - 0.039 13.6 0.4 0.064 12.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) GP41 PF00517.12 CCH57815.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Mannosyl_trans2 PF04188.8 CCH57816.1 - 8.4e-69 232.5 38.4 2.5e-66 224.4 26.6 2.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) Ran_BP1 PF00638.13 CCH57817.1 - 6.2e-53 178.0 2.2 1.2e-52 177.0 1.6 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CCH57817.1 - 0.00035 20.2 1.2 0.0028 17.3 0.8 2.1 1 1 0 1 1 1 1 WH1 domain Cellulose_synt PF03552.9 CCH57817.1 - 0.27 9.4 1.9 0.39 8.9 1.3 1.2 1 0 0 1 1 1 0 Cellulose synthase HMG_box PF00505.14 CCH57818.1 - 3.1e-16 59.3 2.3 7.1e-16 58.2 1.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCH57818.1 - 7e-16 58.3 1.3 1.4e-15 57.4 0.9 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CCH57818.1 - 0.0011 18.7 0.5 0.0023 17.6 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 Prothymosin PF03247.9 CCH57818.1 - 0.027 14.6 20.3 0.11 12.7 14.1 2.0 1 0 0 1 1 1 0 Prothymosin/parathymosin family TFIIA PF03153.8 CCH57818.1 - 1.4 8.7 30.4 2.5 7.8 21.0 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF155 PF02582.9 CCH57819.1 - 2.9e-59 199.9 1.5 5.2e-59 199.0 1.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CCH57819.1 - 0.0045 17.1 0.2 0.068 13.3 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein family UPF0449 DUF77 PF01910.12 CCH57820.1 - 3.7e-27 93.8 0.0 4.3e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Tcp11 PF05794.8 CCH57821.1 - 1.7e-48 165.4 8.1 2.3e-46 158.4 5.6 2.2 1 1 0 1 1 1 1 T-complex protein 11 PRAI PF00697.17 CCH57822.1 - 1.9e-41 141.8 0.2 5.9e-41 140.2 0.1 1.6 1 1 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase RVT_1 PF00078.22 CCH57823.1 - 1.2e-07 31.3 0.4 5.5e-07 29.1 0.1 2.2 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tbf5 PF06331.7 CCH57823.1 - 0.091 12.5 0.2 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 RVT_2 PF07727.9 CCH57825.1 - 3.2e-21 75.4 0.0 4.8e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tubulin-binding PF00418.14 CCH57826.1 - 0.0059 16.2 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Tau and MAP protein, tubulin-binding repeat zf-Apc11 PF12861.2 CCH57827.1 - 4.2e-39 132.2 6.7 6.8e-39 131.6 4.7 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCH57827.1 - 7.6e-26 90.0 10.4 6.9e-25 86.9 7.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCH57827.1 - 1.6e-05 24.6 18.7 0.00022 20.9 13.1 2.5 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CCH57827.1 - 0.0014 18.2 12.8 0.03 14.0 9.4 2.2 1 1 1 2 2 2 1 zinc-RING finger domain FANCL_C PF11793.3 CCH57827.1 - 0.02 14.8 11.4 0.088 12.7 7.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HIT PF04438.11 CCH57827.1 - 0.02 14.4 5.0 0.02 14.4 3.5 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-C3HC4_3 PF13920.1 CCH57827.1 - 0.058 13.0 13.1 0.16 11.6 6.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 CCH57827.1 - 0.11 11.6 0.7 0.14 11.3 0.1 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.1 CCH57827.1 - 0.21 11.2 15.6 0.058 12.9 2.0 3.1 1 1 2 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 CCH57827.1 - 0.22 11.6 15.8 2.3 8.3 11.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH57827.1 - 0.27 10.9 16.5 4 7.1 11.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CCH57827.1 - 0.45 10.5 10.7 0.21 11.6 5.6 1.9 1 1 1 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.1 CCH57827.1 - 1.3 9.2 9.0 3.3 7.9 6.2 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain DZR PF12773.2 CCH57827.1 - 2.2 8.1 9.6 17 5.2 4.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon Mannosyl_trans3 PF11051.3 CCH57828.1 - 6.1e-49 166.8 0.2 1.2e-48 165.8 0.1 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative SSXRD PF09514.5 CCH57828.1 - 0.0076 15.5 1.2 0.048 12.9 0.0 2.6 2 0 0 2 2 2 1 SSXRD motif Zn_clus PF00172.13 CCH57829.1 - 7e-06 25.8 12.0 1.2e-05 25.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.5 CCH57829.1 - 4.4 7.0 14.0 0.49 10.0 6.5 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain Zn_clus PF00172.13 CCH57830.1 - 4.3e-05 23.3 10.5 7.6e-05 22.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD_2 PF06733.10 CCH57831.1 - 2.4e-46 157.3 6.5 5.1e-46 156.2 4.5 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCH57831.1 - 1.6e-44 151.8 0.1 4.3e-44 150.4 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CCH57831.1 - 0.0018 17.7 1.6 0.56 9.6 0.3 3.0 2 1 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH57831.1 - 0.003 17.6 1.7 1.3 9.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 CCH57831.1 - 0.013 14.7 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 CCH57831.1 - 0.3 10.8 0.0 0.59 9.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NAC PF01849.13 CCH57834.1 - 1.1e-13 50.5 0.3 2.4e-13 49.3 0.2 1.6 1 0 0 1 1 1 1 NAC domain DUF755 PF05501.6 CCH57834.1 - 0.29 11.1 5.4 1.1 9.3 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) zf-C2H2 PF00096.21 CCH57835.1 - 1.7e-09 37.4 10.1 0.00025 21.1 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH57835.1 - 1.1e-07 31.6 5.7 0.0082 16.4 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH57835.1 - 0.0019 18.4 8.2 0.0069 16.6 0.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCH57835.1 - 0.058 13.5 5.7 0.27 11.4 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SprT-like PF10263.4 CCH57835.1 - 0.061 12.9 1.9 0.11 12.1 1.3 1.6 1 1 0 1 1 1 0 SprT-like family zf-H2C2_5 PF13909.1 CCH57835.1 - 1.1 9.6 5.1 0.49 10.7 0.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FLILHELTA PF10306.4 CCH57837.1 - 2.7e-20 72.1 0.1 5.9e-20 71.1 0.1 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Vps16_C PF04840.7 CCH57838.1 - 4.7e-68 229.4 17.3 1.1e-67 228.2 12.0 1.6 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CCH57838.1 - 1.5e-44 152.1 3.5 2.6e-44 151.3 2.4 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region DHDPS PF00701.17 CCH57838.1 - 0.17 10.4 1.5 2.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family Skp1_POZ PF03931.10 CCH57839.1 - 2.4e-07 30.7 1.6 2.4e-07 30.7 1.1 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CCH57839.1 - 0.0062 16.5 0.2 0.0071 16.3 0.1 1.1 1 0 0 1 1 1 1 BTB/POZ domain Sgf11 PF08209.6 CCH57840.1 - 1.5e-14 52.9 3.6 2e-14 52.5 2.5 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 CCH57840.1 - 0.021 14.4 1.3 0.03 13.9 0.9 1.2 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF2083 PF09856.4 CCH57840.1 - 0.065 12.8 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 Predicted transcriptional regulator (DUF2083) Catalase PF00199.14 CCH57841.1 - 5.7e-173 574.9 2.5 6.8e-173 574.7 1.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCH57841.1 - 2.3e-12 46.5 0.3 1e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 Catalase-related immune-responsive Peptidase_C48 PF02902.14 CCH57842.1 - 0.0082 15.7 0.1 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GST_C_2 PF13410.1 CCH57843.1 - 2.7e-12 46.3 0.1 5.5e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCH57843.1 - 9.5e-12 44.7 0.0 1.5e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCH57843.1 - 2.4e-10 40.4 0.0 5.8e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCH57843.1 - 2.5e-07 31.0 0.1 4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCH57843.1 - 3.3e-07 30.4 0.0 6.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCH57843.1 - 0.0001 22.2 0.0 0.00027 20.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Arf PF00025.16 CCH57845.1 - 8.1e-46 155.4 0.5 1e-45 155.1 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCH57845.1 - 1e-14 54.2 0.1 1.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH57845.1 - 5.1e-14 52.7 0.1 7.7e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCH57845.1 - 3e-13 49.3 0.2 3.8e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCH57845.1 - 2e-10 39.9 1.6 4e-07 29.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.22 CCH57845.1 - 9.7e-10 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCH57845.1 - 6.7e-09 35.2 0.1 8.5e-09 34.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCH57845.1 - 4.6e-08 33.0 0.1 8.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCH57845.1 - 0.0036 17.4 0.1 0.018 15.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCH57845.1 - 0.02 14.5 0.1 0.038 13.6 0.0 1.6 1 1 1 2 2 2 0 NACHT domain Thymidylate_kin PF02223.12 CCH57845.1 - 0.022 14.1 0.2 0.05 12.9 0.0 1.7 2 0 0 2 2 2 0 Thymidylate kinase FlaC_arch PF05377.6 CCH57845.1 - 0.043 13.7 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.22 CCH57845.1 - 0.06 13.6 0.0 0.078 13.2 0.0 1.3 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 CCH57845.1 - 0.081 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 CCH57845.1 - 0.084 12.7 0.4 0.27 11.1 0.3 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CCH57845.1 - 0.1 11.6 0.3 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Septin Glyco_transf_15 PF01793.11 CCH57847.1 - 2.1e-128 427.9 26.7 7e-128 426.2 18.5 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 CCH57848.1 - 5e-134 446.4 7.2 8e-134 445.7 5.0 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Gly_transf_sug PF04488.10 CCH57849.1 - 1.1e-23 83.5 0.5 2.9e-23 82.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCH57849.1 - 0.015 13.8 1.1 0.54 8.6 0.1 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 CCH57850.1 - 1.8e-94 315.6 3.6 2.7e-94 315.0 2.5 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCH57850.1 - 3.2e-27 94.4 0.1 9.7e-27 92.9 0.1 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) RAMP4 PF06624.7 CCH57851.1 - 0.0027 17.2 0.1 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3394 PF11874.3 CCH57851.1 - 0.095 12.2 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) Peptidase_A2B PF12384.3 CCH57852.1 - 2.9e-12 46.2 0.0 5.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCH57852.1 - 1.6e-05 25.2 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CCH57852.1 - 2.3e-05 24.3 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCH57852.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.21 CCH57854.1 - 2.6e-12 46.9 0.0 6.5e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain NIF PF03031.13 CCH57855.1 - 1.9e-41 141.3 0.3 3.1e-41 140.7 0.2 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CTI PF06934.6 CCH57855.1 - 0.01 14.1 0.5 0.016 13.5 0.3 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) Pro_isomerase PF00160.16 CCH57856.1 - 6.7e-09 36.1 0.0 4e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cadherin-like PF12733.2 CCH57856.1 - 0.037 14.2 0.3 0.072 13.3 0.2 1.5 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain GBA2_N PF12215.3 CCH57856.1 - 0.045 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Cmc1 PF08583.5 CCH57856.1 - 0.064 13.0 0.4 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like VPS28 PF03997.7 CCH57857.1 - 4.1e-67 225.4 1.0 4.7e-67 225.2 0.7 1.0 1 0 0 1 1 1 1 VPS28 protein N6_N4_Mtase PF01555.13 CCH57857.1 - 0.052 13.0 1.9 0.11 12.0 1.4 1.6 1 1 0 1 1 1 0 DNA methylase Imm3 PF14425.1 CCH57857.1 - 0.16 11.9 4.0 0.2 11.5 0.1 2.3 2 1 0 2 2 2 0 Immunity protein Imm3 DUF3890 PF13029.1 CCH57857.1 - 1.3 9.1 4.7 2.2 8.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3890) MCM PF00493.18 CCH57859.1 - 8.7e-135 448.7 0.0 1.6e-134 447.9 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCH57859.1 - 1.1e-27 96.8 0.2 5.9e-27 94.5 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCH57859.1 - 1.1e-07 31.2 0.1 3.1e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCH57859.1 - 2.4e-06 27.3 0.0 2.9e-05 23.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CCH57859.1 - 1e-05 25.8 0.2 4.6e-05 23.7 0.2 2.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCH57859.1 - 0.016 14.7 0.0 0.092 12.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DER1 PF04511.10 CCH57860.1 - 2.8e-38 131.4 13.0 3.4e-38 131.1 9.0 1.1 1 0 0 1 1 1 1 Der1-like family Daxx PF03344.10 CCH57860.1 - 2.1 6.7 25.3 2.8 6.3 17.5 1.0 1 0 0 1 1 1 0 Daxx Family polyprenyl_synt PF00348.12 CCH57861.1 - 9.3e-35 119.7 0.0 1.2e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase PET122 PF05476.6 CCH57861.1 - 0.023 13.9 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 PET122 TEBP_beta PF07404.6 CCH57861.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) SH3_1 PF00018.23 CCH57862.1 - 2e-14 52.6 0.1 1.3e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.19 CCH57862.1 - 8e-14 51.4 0.1 2.1e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 CCH57862.1 - 5.4e-13 48.2 0.2 3.7e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CCH57862.1 - 3.3e-07 29.6 0.1 0.0022 17.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 CCH57862.1 - 4e-06 26.3 0.1 8e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Hydantoinase_B PF02538.9 CCH57863.1 - 9.8e-211 700.5 0.2 1.4e-210 700.0 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CCH57863.1 - 1.1e-90 303.6 0.0 2.4e-90 302.5 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CCH57863.1 - 1.6e-52 177.5 0.6 1.5e-50 171.1 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Aldo_ket_red PF00248.16 CCH57864.1 - 5.3e-46 156.6 0.0 6.4e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mannosyl_trans3 PF11051.3 CCH57865.1 - 1.5e-61 208.0 0.5 2.4e-61 207.4 0.3 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative SIN1 PF05422.7 CCH57865.1 - 0.0025 16.4 0.2 0.004 15.7 0.2 1.2 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) GSHPx PF00255.14 CCH57868.1 - 5.7e-30 102.8 0.3 7.3e-30 102.5 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 CCH57868.1 - 0.00031 20.2 0.1 0.0006 19.3 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCH57868.1 - 0.00053 19.6 0.2 0.0014 18.2 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 CCH57868.1 - 0.0029 17.6 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Ank PF00023.25 CCH57870.1 - 3.5e-15 54.9 0.0 5.9e-07 28.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCH57870.1 - 1.8e-13 50.6 0.1 1.8e-13 50.6 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCH57870.1 - 1e-10 41.7 0.1 6.6e-10 39.2 0.1 2.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH57870.1 - 1.5e-09 37.1 0.2 3.2e-05 23.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCH57870.1 - 2.4e-07 30.7 0.0 2.4e-07 30.7 0.0 5.7 4 1 0 4 4 4 1 Ankyrin repeats (many copies) PPTA PF01239.17 CCH57871.1 - 1.4e-30 103.3 23.6 2.9e-07 29.5 0.1 5.8 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF3373 PF11853.3 CCH57871.1 - 0.011 14.3 0.1 0.018 13.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Bacteriocin_IIi PF11758.3 CCH57871.1 - 0.014 14.9 1.0 0.11 12.1 0.1 2.7 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin BTP PF05232.7 CCH57871.1 - 0.026 14.2 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF2097 PF09870.4 CCH57871.1 - 0.22 11.6 1.4 3.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2097) PSCyt2 PF07583.6 CCH57871.1 - 0.24 10.8 3.4 1.6 8.2 2.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1549) DSPc PF00782.15 CCH57872.1 - 2.6e-25 88.5 2.6 1.7e-24 85.9 0.5 2.7 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCH57872.1 - 0.00023 20.5 0.1 0.00052 19.4 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCH57872.1 - 0.0027 17.7 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Yippee-Mis18 PF03226.9 CCH57872.1 - 0.0068 16.4 1.0 0.042 13.8 0.7 2.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF35_N PF12172.3 CCH57872.1 - 0.036 13.9 3.4 2.2 8.3 0.0 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Elf1 PF05129.8 CCH57872.1 - 0.037 13.7 3.7 5.9 6.6 0.2 3.1 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Apc15p PF05841.6 CCH57873.1 - 2e-20 73.8 4.3 2e-20 73.8 3.0 4.2 2 2 2 4 4 4 1 Apc15p protein Med15 PF09606.5 CCH57873.1 - 0.029 12.5 16.9 0.036 12.2 11.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Phi-29_GP16_7 PF06720.6 CCH57873.1 - 0.068 12.8 0.3 0.068 12.8 0.2 2.6 2 1 1 3 3 3 0 Bacteriophage phi-29 early protein GP16.7 Fungal_trans PF04082.13 CCH57874.1 - 3.2e-21 75.3 0.0 1.2e-20 73.4 0.0 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH57874.1 - 3.7e-07 29.9 11.4 7.7e-07 28.9 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtIP_N PF10482.4 CCH57874.1 - 0.0007 19.3 0.5 0.002 17.9 0.4 1.7 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain DUF972 PF06156.8 CCH57874.1 - 0.0058 16.9 1.1 0.025 14.9 0.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF972) bZIP_1 PF00170.16 CCH57874.1 - 0.15 12.0 2.8 0.41 10.6 2.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor Npa1 PF11707.3 CCH57875.1 - 2.8e-75 253.3 8.8 2.8e-75 253.3 6.1 3.9 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal YjgP_YjgQ PF03739.9 CCH57876.1 - 0.11 11.2 0.9 0.12 11.0 0.6 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family ARPC4 PF05856.7 CCH57877.1 - 1e-72 243.0 4.3 1.1e-72 242.9 3.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ParBc PF02195.13 CCH57878.1 - 3.7e-15 55.8 0.0 7e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 ParB-like nuclease domain Ank PF00023.25 CCH57879.1 - 1.3e-22 78.3 7.3 8e-06 25.4 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 CCH57879.1 - 5.4e-22 77.9 0.3 5.4e-10 39.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCH57879.1 - 6.1e-21 74.3 1.8 4.9e-08 33.2 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH57879.1 - 2.7e-12 45.6 6.2 0.047 13.9 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CCH57879.1 - 5.3e-10 39.2 1.1 0.00013 22.1 0.0 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) PPR_3 PF13812.1 CCH57880.1 - 0.00074 19.6 0.0 0.057 13.7 0.0 3.3 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CCH57880.1 - 0.11 12.4 2.2 2.5 8.1 0.0 3.7 4 0 0 4 4 4 0 PPR repeat family SURF6 PF04935.7 CCH57881.1 - 2e-47 161.2 59.4 2e-47 161.2 41.2 3.0 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 CCH57881.1 - 8.1e-18 64.2 4.5 8.1e-18 64.2 3.1 7.7 5 3 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 V-ATPase_C PF03223.10 CCH57882.1 - 9.4e-121 403.2 4.6 1.1e-120 403.0 3.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF713 PF05218.9 CCH57882.1 - 1.3 8.7 6.7 0.5 10.0 0.4 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF713) Kinesin PF00225.18 CCH57883.1 - 7.2e-46 156.4 12.1 3e-45 154.4 8.4 2.1 1 1 0 1 1 1 1 Kinesin motor domain NDK PF00334.14 CCH57884.1 - 1.6e-56 189.8 0.0 1.7e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Peptidase_M22 PF00814.20 CCH57885.1 - 2.1e-80 270.1 0.0 2.5e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family TrbM PF07424.6 CCH57886.1 - 1.8 8.5 5.8 0.75 9.7 0.9 2.2 2 0 0 2 2 2 0 TrbM PIR PF00399.14 CCH57887.1 - 4.6e-33 111.4 47.9 1.2e-08 33.9 2.7 4.8 4 0 0 4 4 4 4 Yeast PIR protein repeat DUF4644 PF15486.1 CCH57887.1 - 0.14 12.1 2.3 0.24 11.3 1.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4644) DUF973 PF06157.6 CCH57887.1 - 2.1 7.2 6.0 8.2 5.3 1.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF973) NESP55 PF06390.7 CCH57889.1 - 1.5 8.1 7.2 2 7.7 5.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) ABC2_membrane_3 PF12698.2 CCH57889.1 - 2.5 7.0 11.0 2.9 6.8 7.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ashwin PF15323.1 CCH57889.1 - 4.3 7.2 9.4 8.3 6.3 6.5 1.6 1 1 0 1 1 1 0 Developmental protein DNA_primase_S PF01896.14 CCH57890.1 - 6.9e-53 178.3 1.0 1.2e-52 177.5 0.7 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Cellulase PF00150.13 CCH57891.1 - 2.3e-14 53.2 0.6 2.6e-08 33.3 0.1 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) WSC PF01822.14 CCH57892.1 - 6.5e-14 51.6 15.7 6.5e-14 51.6 10.9 3.5 2 1 0 2 2 2 1 WSC domain EphA2_TM PF14575.1 CCH57892.1 - 0.23 11.8 2.1 0.3 11.5 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pox_Ag35 PF03286.9 CCH57892.1 - 4.8 6.6 23.1 0.12 11.8 9.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2408 PF10303.4 CCH57893.1 - 1.7e-63 212.6 21.7 1.6e-39 135.0 2.6 5.0 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) AhpC-TSA PF00578.16 CCH57894.1 - 2.4e-31 107.9 0.0 6.1e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCH57894.1 - 7.6e-21 74.1 0.1 1.9e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CCH57894.1 - 0.0064 16.4 0.3 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme MIP-T3 PF10243.4 CCH57894.1 - 0.01 14.3 28.1 0.01 14.3 19.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Adap_comp_sub PF00928.16 CCH57895.1 - 1.3e-86 289.9 1.4 1.7e-86 289.5 0.9 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCH57895.1 - 2.7e-08 33.6 1.0 5.4e-08 32.6 0.7 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 CCH57895.1 - 0.00032 19.9 0.1 0.0023 17.1 0.0 2.1 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain TPP1 PF10341.4 CCH57896.1 - 3.4e-20 71.9 2.1 4.3e-20 71.6 1.5 1.4 1 1 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD PDZ_2 PF13180.1 CCH57897.1 - 8.2e-05 22.4 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 CCH57897.1 - 0.00033 20.6 0.0 0.00082 19.3 0.0 1.6 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 CCH57897.1 - 0.005 16.9 0.1 0.01 15.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) ERK-JNK_inhib PF15002.1 CCH57897.1 - 0.0084 15.5 0.5 0.019 14.3 0.1 1.6 1 1 0 1 1 1 1 ERK and JNK pathways, inhibitor bZIP_1 PF00170.16 CCH57898.1 - 1.7e-13 50.3 8.0 1.7e-13 50.3 5.5 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCH57898.1 - 1.6e-11 43.8 8.2 3.9e-11 42.5 5.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper KIAA1328 PF15369.1 CCH57898.1 - 0.0097 15.7 3.7 0.024 14.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised protein KIAA1328 bZIP_Maf PF03131.12 CCH57898.1 - 0.026 14.7 5.7 0.026 14.7 4.0 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF904 PF06005.7 CCH57898.1 - 0.03 14.5 9.2 0.13 12.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Gti1_Pac2 PF09729.4 CCH57899.1 - 3.9e-50 170.0 2.1 3.9e-50 170.0 1.5 3.4 2 2 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.22 CCH57900.1 - 2.1e-71 235.7 1.4 1.3e-24 85.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF515 PF04415.7 CCH57900.1 - 0.18 10.0 2.8 1.7 6.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Thioredoxin PF00085.15 CCH57901.1 - 1.7e-24 85.4 6.6 8.4e-21 73.6 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_8 PF13905.1 CCH57901.1 - 0.14 12.3 7.1 2.5 8.2 0.1 4.4 3 1 1 4 4 4 0 Thioredoxin-like Exonuc_VII_L PF02601.10 CCH57901.1 - 0.94 8.5 8.4 1.5 7.9 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit SNARE PF05739.14 CCH57902.1 - 2.1e-09 36.8 1.4 7.5e-09 35.1 0.5 1.9 1 1 1 2 2 2 1 SNARE domain Use1 PF09753.4 CCH57902.1 - 0.0024 17.3 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 SecY PF00344.15 CCH57902.1 - 0.067 12.1 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 SecY translocase Sec8_exocyst PF04048.9 CCH57902.1 - 0.11 12.0 0.8 3.4 7.2 0.1 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Lectin_N PF03954.9 CCH57902.1 - 0.15 11.4 0.8 2.1 7.7 0.0 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DegQ PF08181.6 CCH57902.1 - 0.16 11.6 0.5 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 DegQ (SacQ) family Synaptobrevin PF00957.16 CCH57902.1 - 1.7 8.2 4.2 4 7.1 2.9 1.8 1 1 0 1 1 1 0 Synaptobrevin ParA PF10609.4 CCH57903.1 - 1.6e-36 123.9 0.0 3.5e-36 122.9 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCH57903.1 - 4e-16 59.0 0.0 6.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCH57903.1 - 6.5e-07 28.6 0.0 6.2e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CCH57903.1 - 2.1e-05 23.7 1.0 7.7e-05 21.8 0.2 2.2 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 CCH57903.1 - 4.2e-05 23.5 0.1 0.00055 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCH57903.1 - 0.0071 15.1 0.3 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 ArgK protein Fer4_NifH PF00142.13 CCH57903.1 - 0.011 14.9 0.1 0.22 10.6 0.0 2.2 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 CCH57903.1 - 0.029 13.7 0.1 0.052 12.9 0.1 1.4 1 1 0 1 1 1 0 YhjQ protein zf-C4_ClpX PF06689.8 CCH57903.1 - 0.042 13.3 2.9 0.085 12.3 2.0 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger APS_kinase PF01583.15 CCH57903.1 - 0.046 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 CCH57903.1 - 0.053 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCH57903.1 - 0.078 12.1 0.2 0.24 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RRM_1 PF00076.17 CCH57904.1 - 2.6e-16 59.0 0.4 5.7e-16 57.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH57904.1 - 7.3e-13 48.3 0.2 1.3e-12 47.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH57904.1 - 3.3e-06 26.8 0.4 6.9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CCH57904.1 - 0.046 13.4 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nop16 PF09420.5 CCH57905.1 - 3.4e-59 199.6 12.6 4.2e-59 199.3 8.7 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 GDA1_CD39 PF01150.12 CCH57906.1 - 1.8e-144 481.4 0.2 2.5e-144 481.0 0.2 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CCH57906.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family PUA PF01472.15 CCH57907.1 - 9.6e-21 73.3 0.0 1.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 CCH57907.1 - 0.015 15.0 1.0 0.024 14.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Sec3_C PF09763.4 CCH57908.1 - 1.2e-129 433.5 35.3 1.2e-129 433.5 24.4 3.1 3 2 1 4 4 4 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CCH57908.1 - 7.3e-24 83.4 7.8 1.5e-23 82.4 2.0 3.2 3 0 0 3 3 3 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Polysacc_synt PF01943.12 CCH57908.1 - 0.14 11.3 0.1 0.26 10.4 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NTF2 PF02136.15 CCH57909.1 - 1.7e-36 125.1 0.4 1.9e-36 125.0 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 CCH57909.1 - 0.00021 20.4 0.1 0.00031 19.8 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.1 CCH57909.1 - 0.018 15.2 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DnaJ-X PF14308.1 CCH57910.1 - 3.5e-56 189.6 1.3 3.5e-56 189.6 0.9 2.4 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCH57910.1 - 6.4e-26 89.8 2.1 6.4e-26 89.8 1.5 2.2 2 0 0 2 2 2 1 DnaJ domain SOBP PF15279.1 CCH57910.1 - 0.006 17.0 1.1 0.0092 16.3 0.7 1.4 1 0 0 1 1 1 1 Sine oculis-binding protein Hid1 PF12722.2 CCH57910.1 - 0.19 9.3 13.0 0.31 8.6 9.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CCH57910.1 - 0.82 8.0 3.5 1.1 7.6 2.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP1_TIP1 PF00660.12 CCH57911.1 - 1.2e-25 89.3 1.8 3.1e-25 88.0 1.3 1.6 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 CCH57911.1 - 3.3e-06 26.2 7.3 3.3e-06 26.2 5.1 3.0 2 0 0 2 2 1 1 Yeast PIR protein repeat Herpes_BLLF1 PF05109.8 CCH57911.1 - 0.012 13.6 20.1 0.012 13.6 13.9 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF605 PF04652.11 CCH57911.1 - 0.043 13.2 16.3 0.051 12.9 11.3 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CCH57911.1 - 0.045 13.6 17.4 0.056 13.3 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAGA_bind PF06217.7 CCH57911.1 - 0.22 11.4 7.4 0.26 11.2 5.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S64 PF08192.6 CCH57911.1 - 1.1 7.4 13.3 1.3 7.2 9.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 CCH57911.1 - 1.3 6.5 11.1 1.5 6.3 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CCH57911.1 - 2.2 7.5 20.3 4 6.7 14.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 CCH57911.1 - 2.3 6.9 25.2 3.2 6.4 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mitofilin PF09731.4 CCH57911.1 - 2.5 6.6 20.4 3.6 6.1 14.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOBP PF15279.1 CCH57911.1 - 2.5 8.3 11.7 3.2 8.0 8.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Neur_chan_memb PF02932.11 CCH57911.1 - 3 7.6 7.5 4.2 7.1 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 CCH57911.1 - 3 6.6 15.9 4.9 6.0 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 CCH57911.1 - 5.9 6.6 16.7 8.2 6.2 11.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 CCH57911.1 - 6 5.5 13.4 8.2 5.1 9.3 1.2 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.14 CCH57911.1 - 6.1 5.4 8.4 8.5 4.9 5.8 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SRP1_TIP1 PF00660.12 CCH57912.1 - 2.2e-28 98.1 0.2 4e-28 97.2 0.2 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family CAP_N PF01213.14 CCH57912.1 - 0.088 12.0 3.6 0.13 11.5 2.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Macoilin PF09726.4 CCH57912.1 - 0.78 7.9 11.6 0.81 7.8 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 CCH57912.1 - 3.6 6.0 6.4 3.8 6.0 4.5 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF533 PF04391.7 CCH57912.1 - 8.4 5.7 7.7 5.5 6.3 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF533) Methyltransf_6 PF03737.10 CCH57913.1 - 4.9e-29 101.1 0.0 6.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase SRP1_TIP1 PF00660.12 CCH57914.1 - 2.9e-24 84.8 1.4 2.9e-24 84.8 1.0 1.8 1 1 1 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.14 CCH57914.1 - 4.9e-06 25.6 5.5 4.9e-06 25.6 3.8 2.7 2 0 0 2 2 2 1 Yeast PIR protein repeat LPP PF04728.8 CCH57914.1 - 0.0043 16.8 0.4 0.021 14.6 0.3 2.2 1 1 1 2 2 2 2 Lipoprotein leucine-zipper COG2 PF06148.6 CCH57914.1 - 0.041 13.7 2.9 1.3 8.9 0.4 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ICAT PF06384.6 CCH57914.1 - 0.047 13.4 0.3 0.14 11.9 0.2 1.8 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT DivIVA PF05103.8 CCH57914.1 - 0.32 11.0 2.5 0.6 10.1 1.8 1.5 1 0 0 1 1 1 0 DivIVA protein GSH_synth_ATP PF03917.12 CCH57914.1 - 0.44 9.0 5.4 4.3 5.8 3.7 2.1 1 1 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain FlaC_arch PF05377.6 CCH57914.1 - 1.2 9.0 4.3 1 9.3 0.4 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DNA_pol_viral_N PF00242.12 CCH57914.1 - 2.6 7.0 6.7 3.1 6.7 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ABC2_membrane PF01061.19 CCH57915.1 - 5.9e-64 215.0 57.7 3.3e-32 111.3 20.7 2.7 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCH57915.1 - 7.4e-34 116.9 0.0 1.2e-17 64.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCH57915.1 - 2.3e-26 91.4 17.8 1.7e-23 82.2 0.7 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CCH57915.1 - 2.4e-06 26.8 58.0 0.00033 19.7 10.5 4.0 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.14 CCH57915.1 - 3.4e-05 23.1 0.0 0.0024 17.1 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CCH57915.1 - 4e-05 22.8 0.1 8.1e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CCH57915.1 - 0.00049 20.1 23.8 0.00091 19.2 1.4 4.9 3 2 1 4 4 4 1 AAA domain AAA_18 PF13238.1 CCH57915.1 - 0.0011 19.2 0.1 0.0051 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CCH57915.1 - 0.013 14.9 0.2 0.028 13.8 0.2 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CCH57915.1 - 0.017 15.2 0.0 0.053 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCH57915.1 - 0.052 13.5 0.1 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CCH57915.1 - 0.066 12.7 1.2 0.29 10.6 0.7 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCH57915.1 - 0.22 10.8 0.0 0.64 9.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCH57915.1 - 4.3 7.6 9.2 0.072 13.4 0.4 2.3 2 1 0 2 2 2 0 AAA domain Mannosyl_trans3 PF11051.3 CCH57916.1 - 1.9e-61 207.7 1.4 2.8e-61 207.2 1.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative HMG_box PF00505.14 CCH57917.1 - 4.3e-11 42.9 2.4 1e-10 41.7 1.6 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCH57917.1 - 3.1e-06 27.4 1.8 3.1e-06 27.4 1.2 1.8 1 1 0 1 1 1 1 HMG-box domain Protocadherin PF08374.6 CCH57917.1 - 0.32 10.5 3.3 0.17 11.4 0.8 1.6 2 0 0 2 2 2 0 Protocadherin PIR PF00399.14 CCH57919.1 - 8.5e-18 62.9 15.0 9.5e-09 34.2 2.7 2.9 2 0 0 2 2 2 2 Yeast PIR protein repeat Mpv17_PMP22 PF04117.7 CCH57920.1 - 5.7e-22 77.1 0.7 1.2e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family PspC PF04024.7 CCH57920.1 - 0.085 12.3 1.0 0.14 11.6 0.7 1.3 1 0 0 1 1 1 0 PspC domain Zn_clus PF00172.13 CCH57921.1 - 5.9e-08 32.4 10.4 1.2e-07 31.4 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ferric_reduct PF01794.14 CCH57922.1 - 3e-19 69.3 14.1 3e-19 69.3 9.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCH57922.1 - 2.3e-16 60.0 0.0 4.1e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCH57922.1 - 4.2e-08 33.0 0.1 9.7e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 CCH57922.1 - 0.0052 17.3 0.0 1.7 9.2 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Sugar_tr PF00083.19 CCH57923.1 - 5.1e-160 532.9 30.2 5.8e-160 532.7 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH57923.1 - 9.9e-32 110.0 30.6 2.1e-29 102.3 12.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH57923.1 - 1.6e-06 26.6 2.2 1.6e-06 26.6 1.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCH57923.1 - 0.25 9.3 6.1 0.034 12.2 1.1 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 CCH57924.1 - 7.1e-155 515.9 30.0 8e-155 515.8 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH57924.1 - 5.9e-33 114.0 27.1 1.5e-30 106.1 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH57924.1 - 1e-06 27.3 1.5 1e-06 27.3 1.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCH57924.1 - 0.041 12.0 4.5 0.015 13.4 0.8 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Clat_adaptor_s PF01217.15 CCH57925.1 - 5.1e-55 185.0 3.4 6e-55 184.8 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MFS_1 PF07690.11 CCH57926.1 - 4.7e-23 81.4 51.6 2.4e-20 72.5 21.7 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH57926.1 - 1.1e-06 27.5 32.4 6.9e-05 21.6 7.2 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter UQ_con PF00179.21 CCH57928.1 - 3.4e-38 130.2 0.1 4.4e-38 129.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CDC45 PF02724.9 CCH57928.1 - 0.017 13.2 8.5 0.019 13.0 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 CCH57928.1 - 0.038 14.0 8.0 0.051 13.5 5.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RWD PF05773.17 CCH57928.1 - 0.063 13.1 0.1 0.088 12.7 0.0 1.5 1 1 0 1 1 1 0 RWD domain DUF3245 PF11595.3 CCH57928.1 - 0.12 12.7 7.8 0.21 11.8 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) BTV_NS2 PF04514.7 CCH57928.1 - 2.2 7.0 9.8 5.8 5.6 6.5 1.7 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 RXT2_N PF08595.6 CCH57928.1 - 3.2 7.5 11.3 7 6.4 7.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 CCH57928.1 - 4.2 7.0 6.8 6.2 6.4 4.7 1.3 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 CCH57928.1 - 5.4 6.1 13.6 7.1 5.7 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 CCH57928.1 - 9.7 5.7 21.6 4.6 6.8 13.5 1.6 1 1 0 1 1 1 0 Sigma-70, non-essential region LSM PF01423.17 CCH57930.1 - 3.3e-11 42.5 0.2 4.3e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain TENA_THI-4 PF03070.11 CCH57931.1 - 3.3e-09 36.8 5.2 5.4e-09 36.1 3.6 1.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family Arm PF00514.18 CCH57932.1 - 1.3e-68 224.6 30.1 1.8e-11 43.4 0.0 11.1 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCH57932.1 - 2e-23 82.4 9.8 1.8e-06 28.1 0.1 7.5 2 2 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 CCH57932.1 - 5.9e-15 55.2 14.1 0.00025 21.4 0.2 7.3 6 2 2 8 8 8 3 HEAT-like repeat HEAT PF02985.17 CCH57932.1 - 8.2e-15 53.4 24.9 0.02 14.9 0.1 10.5 11 0 0 11 11 11 3 HEAT repeat KAP PF05804.7 CCH57932.1 - 1.5e-11 42.9 0.2 3.6e-11 41.7 0.1 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CCH57932.1 - 2.6e-10 39.8 7.5 8.7e-05 21.7 0.3 3.8 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 CCH57932.1 - 3.9e-10 38.6 11.3 3.9e-07 28.7 1.3 3.1 1 1 2 3 3 3 3 Adaptin N terminal region DUF2454 PF10521.4 CCH57932.1 - 2.1e-05 23.6 0.1 0.034 13.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 CCH57932.1 - 0.00011 22.4 0.1 0.19 12.1 0.0 3.6 1 1 0 2 2 2 1 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 CCH57932.1 - 0.019 14.8 4.3 0.76 9.7 0.1 4.2 3 1 2 5 5 5 0 V-ATPase subunit H YjeF_N PF03853.10 CCH57933.1 - 2.8e-25 88.8 0.0 5.6e-25 87.8 0.0 1.5 1 1 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 CCH57933.1 - 8.4e-09 35.9 16.4 8.4e-09 35.9 11.4 3.6 2 1 0 2 2 2 1 FDF domain Ras PF00071.17 CCH57934.1 - 1.2e-22 80.0 0.5 1.8e-12 46.9 0.3 3.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 CCH57934.1 - 2.2e-06 28.1 0.3 0.2 12.1 0.0 3.6 2 1 1 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 CCH57934.1 - 0.00034 20.5 2.8 0.00096 19.1 0.5 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Phosphodiest PF01663.17 CCH57935.1 - 6.8e-39 134.2 1.7 1.2e-38 133.4 1.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PMP1_2 PF08114.6 CCH57936.1 - 4.1e-16 58.1 1.5 4.3e-16 58.1 1.0 1.0 1 0 0 1 1 1 1 ATPase proteolipid family DUF1049 PF06305.6 CCH57936.1 - 0.036 13.5 0.3 0.044 13.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2069 PF09842.4 CCH57936.1 - 0.085 12.8 0.0 0.094 12.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) P12 PF12669.2 CCH57936.1 - 0.13 12.4 3.1 0.15 12.2 2.2 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family TMEMspv1-c74-12 PF11044.3 CCH57936.1 - 0.21 11.1 2.0 0.28 10.7 1.4 1.4 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2461 PF09365.5 CCH57937.1 - 0.17 11.2 4.4 0.063 12.6 1.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) RFC1 PF08519.7 CCH57937.1 - 4.1 7.1 7.5 1.3 8.7 2.3 2.0 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain zf-Nse PF11789.3 CCH57938.1 - 5.3e-19 67.4 1.1 1.4e-18 66.1 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit PTPA PF03095.10 CCH57938.1 - 0.039 13.1 0.2 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein ParB PF08775.5 CCH57938.1 - 0.09 13.0 5.0 0.072 13.4 1.3 2.2 1 1 1 2 2 2 0 ParB family FliS PF02561.9 CCH57938.1 - 0.14 12.0 2.8 0.27 11.1 1.9 1.4 1 0 0 1 1 1 0 Flagellar protein FliS zf-MIZ PF02891.15 CCH57938.1 - 0.99 8.9 6.8 1.1 8.8 2.8 2.5 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger tRNA-synt_2 PF00152.15 CCH57939.1 - 7.6e-77 258.3 0.0 1.1e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCH57939.1 - 8.8e-07 28.7 0.1 3.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCH57939.1 - 0.00019 20.7 0.0 0.67 9.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) ssDNA-exonuc_C PF10141.4 CCH57939.1 - 0.012 15.1 0.5 0.033 13.6 0.1 1.8 2 0 0 2 2 2 0 Single-strand DNA-specific exonuclease, C terminal domain Abi_2 PF07751.6 CCH57939.1 - 0.13 12.4 1.5 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Abi-like protein Siah-Interact_N PF09032.6 CCH57939.1 - 0.27 11.3 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal MFS_1 PF07690.11 CCH57940.1 - 1.2e-28 99.8 9.0 4.7e-28 97.9 6.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CCH57940.1 - 0.00028 19.4 6.0 0.00028 19.4 4.2 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 CCH57940.1 - 0.0012 17.1 0.4 0.0012 17.1 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CCH57941.1 - 6.6e-29 100.7 13.7 2.1e-28 99.0 9.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 CCH57941.1 - 0.0077 16.0 5.6 0.32 10.8 0.0 3.5 3 0 0 3 3 3 2 MFS_1 like family zf-Tim10_DDP PF02953.10 CCH57942.1 - 2.2e-20 71.7 5.9 3e-20 71.2 4.1 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Gemini_AL1_M PF08283.6 CCH57942.1 - 0.028 14.2 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Geminivirus rep protein central domain Ku_PK_bind PF08785.6 CCH57942.1 - 0.038 13.8 2.1 0.043 13.7 1.4 1.1 1 0 0 1 1 1 0 Ku C terminal domain like Mmp37 PF09139.6 CCH57942.1 - 0.051 12.5 0.4 0.054 12.5 0.3 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Phasin_2 PF09361.5 CCH57942.1 - 0.053 13.5 0.3 0.21 11.6 0.1 1.9 1 1 1 2 2 2 0 Phasin protein Pepsin-I3 PF06394.8 CCH57942.1 - 0.16 11.6 2.1 3 7.5 0.0 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Aminotran_1_2 PF00155.16 CCH57943.1 - 7e-65 219.3 0.0 8.7e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CCH57943.1 - 6.9e-07 27.8 0.0 1.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CCH57943.1 - 7.9e-05 21.9 0.0 0.00024 20.3 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCH57943.1 - 0.00011 21.0 0.0 0.0002 20.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Reticulon PF02453.12 CCH57944.1 - 5.2e-36 123.7 4.4 7.2e-36 123.3 3.1 1.1 1 0 0 1 1 1 1 Reticulon DUF2547 PF10818.3 CCH57944.1 - 0.056 14.0 0.1 0.11 13.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2547) Aconitase PF00330.15 CCH57945.1 - 2.2e-79 267.1 0.0 1.1e-48 165.8 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCH57945.1 - 6.5e-24 84.5 0.0 1.3e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Porphobil_deam PF01379.15 CCH57946.1 - 5.4e-81 270.6 0.0 7.1e-81 270.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CCH57946.1 - 2.2e-16 59.6 0.9 3.7e-16 58.9 0.6 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain WD40 PF00400.27 CCH57947.1 - 4e-16 58.1 13.0 2.2e-05 24.1 0.3 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 CCH57947.1 - 0.0076 15.9 0.3 0.048 13.3 0.1 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 CCH57947.1 - 0.012 14.8 0.3 0.068 12.3 0.1 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity mRNA_cap_C PF03919.10 CCH57947.1 - 0.04 14.2 0.2 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain DASH_Dad3 PF08656.5 CCH57948.1 - 1.7e-17 62.8 4.9 2.3e-17 62.4 3.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 TALPID3 PF15324.1 CCH57948.1 - 0.0044 14.4 0.7 0.0053 14.1 0.5 1.0 1 0 0 1 1 1 1 Hedgehog signalling target DUF3573 PF12097.3 CCH57948.1 - 0.11 11.1 2.5 0.11 11.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1546 PF07571.8 CCH57949.1 - 2.8e-27 94.6 0.0 1.5e-26 92.2 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CCH57949.1 - 4.7e-25 87.3 0.1 8.7e-25 86.4 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CCH57949.1 - 0.022 14.8 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 RP-C_C PF11800.3 CCH57949.1 - 0.12 12.0 0.7 0.3 10.7 0.5 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region SLD3 PF08639.5 CCH57950.1 - 7.9e-60 202.9 37.7 2.8e-59 201.1 26.1 1.8 1 1 0 1 1 1 1 DNA replication regulator SLD3 BCNT PF07572.7 CCH57951.1 - 2.1e-27 94.8 0.4 2.1e-27 94.8 0.3 2.6 2 1 1 3 3 3 1 Bucentaur or craniofacial development CBS PF00571.23 CCH57952.1 - 3.8e-32 109.8 1.7 1.2e-11 44.1 0.0 4.5 4 1 0 4 4 4 4 CBS domain HTH_9 PF08221.6 CCH57952.1 - 0.073 12.9 0.6 1.1 9.1 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain WD40 PF00400.27 CCH57953.1 - 3e-21 74.4 13.1 1.2e-06 28.2 0.2 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCH57953.1 - 0.035 13.6 0.1 5.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FcoT PF10862.3 CCH57953.1 - 0.076 12.5 0.5 0.31 10.5 0.1 2.2 3 0 0 3 3 3 0 FcoT-like thioesterase domain DUF3484 PF11983.3 CCH57953.1 - 0.37 11.6 4.3 6 7.7 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) zf-RING_UBOX PF13445.1 CCH57954.1 - 7.7e-14 51.1 3.5 2.6e-13 49.4 2.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CCH57954.1 - 5.4e-07 29.4 6.1 5.4e-07 29.4 4.2 2.1 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 CCH57954.1 - 7.8e-05 22.4 3.2 0.00014 21.5 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CCH57954.1 - 0.00011 21.9 1.3 0.00032 20.5 0.9 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCH57954.1 - 0.0002 21.0 3.1 0.00043 19.9 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCH57954.1 - 0.0027 17.6 3.5 0.0061 16.5 2.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH57954.1 - 0.0046 16.6 1.8 0.0089 15.6 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 CCH57954.1 - 0.0064 15.9 3.1 0.012 15.0 2.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 CCH57954.1 - 0.0079 15.8 4.6 0.019 14.5 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-N PF05238.8 CCH57955.1 - 1.7e-98 330.3 1.9 2.4e-98 329.8 1.3 1.2 1 0 0 1 1 1 1 Kinetochore protein CHL4 like RRM_1 PF00076.17 CCH57956.1 - 3.9e-55 183.3 0.6 1.2e-17 63.2 0.1 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH57956.1 - 4.1e-44 148.4 0.4 9.3e-12 44.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH57956.1 - 1.4e-21 76.0 0.8 9.5e-08 31.7 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CCH57957.1 - 2.5e-53 180.9 0.1 2.5e-53 180.9 0.1 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH57957.1 - 1.3e-26 93.2 0.1 2.5e-25 89.0 0.1 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Epimerase PF01370.16 CCH57958.1 - 5.3e-21 75.1 0.1 1.1e-20 74.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCH57958.1 - 1.1e-11 43.9 0.1 1.6e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCH57958.1 - 2.6e-10 40.5 0.1 6.5e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCH57958.1 - 4.2e-10 38.9 0.2 3e-09 36.2 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCH57958.1 - 1.4e-08 34.8 0.0 3.2e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCH57958.1 - 3.1e-07 29.5 1.0 1e-06 27.8 0.2 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 CCH57958.1 - 5e-05 23.0 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CCH57958.1 - 0.00012 21.1 0.0 0.0073 15.2 0.0 2.5 2 1 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 CCH57958.1 - 0.00026 20.3 0.1 0.00099 18.4 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 CCH57958.1 - 0.0079 16.1 0.0 0.063 13.1 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 CCH57958.1 - 0.012 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase tRNA-synt_1 PF00133.17 CCH57959.1 - 1.5e-155 518.5 1.1 2e-155 518.1 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCH57959.1 - 3.5e-21 75.5 2.2 1.2e-20 73.8 1.5 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCH57959.1 - 2.7e-20 72.4 7.5 6.8e-11 41.4 0.1 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 CCH57959.1 - 0.001 18.6 4.6 0.0019 17.8 3.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 CCH57959.1 - 0.019 14.2 0.0 0.082 12.1 0.0 2.0 1 1 1 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 zf-UDP PF14569.1 CCH57959.1 - 0.052 13.3 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.2 CCH57959.1 - 0.22 11.3 1.4 0.43 10.4 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 CCH57960.1 - 2.3e-10 40.1 12.2 7.1e-06 26.0 0.7 2.8 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH57960.1 - 1.6e-09 37.4 3.0 0.00057 20.0 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH57960.1 - 7.5e-05 22.8 5.8 0.00012 22.1 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CCH57960.1 - 0.0025 17.6 2.3 0.38 10.7 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger C1_4 PF07975.7 CCH57960.1 - 0.0067 16.4 1.7 0.47 10.4 0.0 2.5 2 0 0 2 2 2 1 TFIIH C1-like domain zf-BED PF02892.10 CCH57960.1 - 0.039 13.7 6.1 0.47 10.2 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 CCH57960.1 - 0.078 13.1 9.5 0.18 12.0 0.6 2.9 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 CCH57960.1 - 0.081 12.8 2.8 0.16 11.8 1.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2_3 PF13878.1 CCH57960.1 - 0.094 12.3 6.3 0.12 12.0 1.0 2.5 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-CHY PF05495.7 CCH57960.1 - 0.12 12.5 5.9 0.25 11.5 1.2 2.2 1 1 1 2 2 2 0 CHY zinc finger XPA_N PF01286.13 CCH57960.1 - 0.15 11.7 1.6 5.4 6.7 0.1 2.4 2 0 0 2 2 2 0 XPA protein N-terminal SprT-like PF10263.4 CCH57960.1 - 0.2 11.2 3.5 0.68 9.5 2.4 1.9 1 1 0 1 1 1 0 SprT-like family Zn-ribbon_8 PF09723.5 CCH57960.1 - 0.39 10.7 4.7 2 8.4 0.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 CCH57960.1 - 0.43 10.8 4.5 1.3 9.3 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 CCH57960.1 - 0.85 10.2 4.3 3.5 8.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2_2 PF12756.2 CCH57960.1 - 8.8 6.5 10.1 18 5.5 2.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 CCH57963.1 - 1.9e-73 246.8 0.0 1.9e-72 243.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH57963.1 - 2.2e-36 125.2 0.0 3.3e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH57963.1 - 6.5e-05 22.0 0.1 0.00023 20.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCH57963.1 - 0.018 14.8 0.0 0.081 12.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1573 PF07610.6 CCH57963.1 - 0.1 12.1 0.3 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) Thiolase_N PF00108.18 CCH57964.1 - 1.9e-102 341.7 1.8 2.4e-102 341.4 1.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCH57964.1 - 6.9e-43 144.9 0.6 1.5e-42 143.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCH57964.1 - 0.022 14.2 1.9 0.041 13.3 1.0 1.6 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCH57964.1 - 0.075 12.7 0.8 2.4 7.8 0.4 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AAA_17 PF13207.1 CCH57965.1 - 4.6e-08 33.8 0.1 6.2e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH57965.1 - 1.5e-07 31.7 0.2 3.1e-07 30.7 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH57965.1 - 7.4e-06 25.8 0.0 2.8e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCH57965.1 - 2.6e-05 23.9 0.0 3.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 CCH57965.1 - 8.8e-05 22.1 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 CCH57965.1 - 9.9e-05 22.1 0.6 0.0003 20.5 0.1 1.8 1 1 1 2 2 2 1 Archaeal ATPase CbiA PF01656.18 CCH57965.1 - 0.00081 18.8 0.5 0.19 11.0 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 CCH57965.1 - 0.0031 16.9 0.0 0.012 15.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 CCH57965.1 - 0.0035 17.4 0.0 0.015 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 CCH57965.1 - 0.0058 16.5 0.2 0.0081 16.0 0.2 1.2 1 0 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.7 CCH57965.1 - 0.008 15.2 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 CCH57965.1 - 0.0086 15.9 0.0 0.021 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCH57965.1 - 0.015 15.2 0.0 0.057 13.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.16 CCH57965.1 - 0.016 14.6 0.4 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase T2SE PF00437.15 CCH57965.1 - 0.02 13.7 0.1 0.055 12.3 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 CCH57965.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 CCH57965.1 - 0.024 14.5 0.0 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 CCH57965.1 - 0.03 14.2 0.3 0.069 13.1 0.2 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 CCH57965.1 - 0.038 13.6 0.2 0.085 12.5 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCH57965.1 - 0.065 13.4 0.1 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 CCH57965.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 CCH57966.1 - 1.2e-49 168.7 0.3 1.4e-48 165.3 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH57966.1 - 2.9e-20 72.4 0.0 6.1e-18 64.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH57966.1 - 5.6e-08 32.0 0.0 3.3e-07 29.5 0.0 2.0 1 1 0 2 2 2 1 Kinase-like ARID PF01388.16 CCH57967.1 - 2.2e-20 72.3 0.7 2.2e-20 72.3 0.5 4.1 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain Glyco_transf_34 PF05637.7 CCH57968.1 - 4.7e-75 252.1 0.9 5.8e-75 251.8 0.6 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.11 CCH57968.1 - 0.0035 17.1 0.1 0.0058 16.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.9 CCH57968.1 - 0.013 14.8 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF273 Glyco_tranf_2_4 PF13704.1 CCH57968.1 - 0.06 13.6 0.6 0.39 11.0 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 2 TPR_11 PF13414.1 CCH57969.1 - 1.5e-21 75.7 2.9 1.2e-09 37.6 0.0 4.5 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 CCH57969.1 - 8.8e-18 63.0 2.3 2e-05 23.9 0.0 5.9 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCH57969.1 - 1.7e-15 55.6 0.4 0.00042 20.0 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCH57969.1 - 7.3e-13 47.6 7.9 0.039 14.1 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCH57969.1 - 8.3e-13 47.7 0.0 0.0039 17.6 0.2 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCH57969.1 - 1.2e-11 44.8 0.1 5.4e-05 23.7 0.0 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCH57969.1 - 2.5e-10 40.5 0.5 0.057 13.7 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 CCH57969.1 - 1.8e-08 34.4 1.1 0.17 12.0 0.0 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH57969.1 - 1.5e-06 28.0 3.1 0.00037 20.3 0.0 3.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCH57969.1 - 4.3e-06 26.1 1.4 1.1 9.2 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCH57969.1 - 0.00011 22.0 0.0 0.053 13.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCH57969.1 - 0.00042 19.8 0.2 0.66 9.9 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCH57969.1 - 0.00072 19.8 0.1 17 6.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CCH57969.1 - 0.0019 18.3 2.8 0.12 12.4 0.1 3.4 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CCH57969.1 - 0.007 15.4 0.1 0.031 13.3 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.21 CCH57970.1 - 1.4e-25 88.6 0.2 2.6e-25 87.7 0.1 1.5 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adaptin_N PF01602.15 CCH57971.1 - 5.4e-107 358.3 13.2 9.1e-107 357.5 9.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CCH57971.1 - 5.6e-59 197.5 0.0 1.8e-58 195.8 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CCH57971.1 - 5.5e-53 178.4 0.1 5.5e-53 178.4 0.1 2.7 3 0 0 3 3 3 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CCH57971.1 - 2e-08 34.3 3.5 5.5e-05 23.3 0.0 4.2 2 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 CCH57971.1 - 0.002 18.0 5.8 0.47 10.2 0.0 4.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCH57971.1 - 0.024 14.6 0.0 1 9.6 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.1 CCH57971.1 - 0.067 13.7 0.1 6.7 7.3 0.0 3.9 3 1 0 3 3 3 0 HEAT-like repeat IZUMO PF15005.1 CCH57971.1 - 0.65 10.0 3.9 0.39 10.7 0.2 2.5 2 0 0 2 2 2 0 Izumo sperm-egg fusion GLE1 PF07817.8 CCH57972.1 - 4.8e-86 287.8 0.3 4.8e-86 287.8 0.2 2.1 2 1 0 2 2 2 1 GLE1-like protein LMBR1 PF04791.11 CCH57972.1 - 0.034 12.7 7.3 0.25 9.8 5.0 2.1 1 1 0 1 1 1 0 LMBR1-like membrane protein Na_Ca_ex PF01699.19 CCH57973.1 - 7e-48 161.7 19.5 2.9e-27 94.9 3.8 3.8 3 1 1 4 4 4 2 Sodium/calcium exchanger protein OPT PF03169.10 CCH57976.1 - 2.7e-129 432.4 32.8 3.3e-129 432.1 22.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AA_permease PF00324.16 CCH57977.1 - 3.7e-50 170.6 41.3 4.9e-50 170.2 28.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH57977.1 - 2.9e-14 52.4 46.8 5.9e-14 51.4 32.4 1.4 1 0 0 1 1 1 1 Amino acid permease EF-hand_7 PF13499.1 CCH57979.1 - 5.3e-12 45.6 3.2 7.6e-09 35.5 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCH57979.1 - 9.9e-09 33.8 4.2 0.00051 19.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CCH57979.1 - 8.1e-08 31.7 2.3 7.8e-05 22.2 0.1 3.8 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CCH57979.1 - 2.1e-07 30.7 0.0 0.0029 17.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 CCH57979.1 - 2.1e-07 30.2 5.9 0.0012 18.5 0.1 3.5 4 1 0 4 4 4 2 EF-hand domain UPF0154 PF03672.8 CCH57979.1 - 0.015 14.9 0.0 0.089 12.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 CCH57979.1 - 0.039 13.3 5.0 0.6 9.5 0.1 3.2 3 0 0 3 3 3 0 EF hand HD_3 PF13023.1 CCH57980.1 - 3.3e-37 127.7 1.1 4.2e-37 127.4 0.8 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CCH57980.1 - 4.1e-06 26.8 1.5 2.9e-05 24.0 1.0 2.2 1 1 0 1 1 1 1 HD domain Cactin_mid PF10312.4 CCH57980.1 - 0.09 12.0 3.2 4 6.6 0.6 2.2 1 1 1 2 2 2 0 Conserved mid region of cactin WD40 PF00400.27 CCH57981.1 - 8.4e-10 38.1 4.5 0.022 14.6 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat RCC1 PF00415.13 CCH57982.1 - 3.2e-55 184.1 0.6 4.8e-07 29.8 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCH57982.1 - 6e-35 118.1 17.6 4.6e-09 35.6 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat DAHP_synth_1 PF00793.15 CCH57983.1 - 6.4e-103 343.1 0.0 7.7e-103 342.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF4116 PF13475.1 CCH57983.1 - 0.077 12.5 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) RRM_1 PF00076.17 CCH57984.1 - 7.5e-15 54.3 0.1 1.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH57984.1 - 5.4e-11 42.3 0.0 8.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH57984.1 - 1.7e-07 30.9 0.1 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 CCH57985.1 - 2e-11 43.4 7.0 3.9e-11 42.4 4.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCH57985.1 - 1.5 8.1 5.6 2.8 7.3 3.9 1.4 1 0 0 1 1 1 0 PHD-finger Sec1 PF00995.18 CCH57986.1 - 4e-132 441.7 24.3 4.6e-132 441.5 16.8 1.0 1 0 0 1 1 1 1 Sec1 family TCO89 PF10452.4 CCH57987.1 - 7.4e-98 329.0 96.9 2.7e-95 320.5 67.1 2.2 1 1 0 1 1 1 1 TORC1 subunit TCO89 WD40 PF00400.27 CCH57988.1 - 2.1e-24 84.4 16.7 1.4e-08 34.3 0.0 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat DUF4476 PF14771.1 CCH57988.1 - 0.029 14.3 2.0 0.063 13.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) YmzC PF14157.1 CCH57988.1 - 7.2 6.5 16.2 0.082 12.7 0.2 4.7 6 0 0 6 6 6 0 YmzC-like protein Nup96 PF12110.3 CCH57989.1 - 7e-55 186.1 4.6 7e-55 186.1 3.2 1.8 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CCH57989.1 - 6.5e-49 165.3 0.0 2e-48 163.8 0.0 1.9 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCH57989.1 - 2.9e-15 56.4 87.7 3.4e-09 36.9 26.2 4.9 3 1 2 5 5 5 3 Nucleoporin FG repeat region ParA PF10609.4 CCH57990.1 - 3e-36 123.1 0.0 6.3e-36 122.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCH57990.1 - 1.8e-16 60.1 0.0 2.5e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCH57990.1 - 1.4e-06 27.5 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CCH57990.1 - 2.8e-05 24.1 0.0 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CCH57990.1 - 2.9e-05 23.2 0.1 0.0033 16.5 0.0 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 CCH57990.1 - 0.0031 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCH57990.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.1 CCH57990.1 - 0.067 12.7 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP1_OBG PF01018.17 CCH57990.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 GTP1/OBG Rad17 PF03215.10 CCH57990.1 - 0.19 10.3 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein UQ_con PF00179.21 CCH57991.1 - 2.1e-16 59.5 0.0 2.5e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCH57991.1 - 0.0062 16.4 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Exonuc_VII_L PF02601.10 CCH57993.1 - 1.6 7.8 8.9 16 4.5 0.0 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit MPC PF03650.8 CCH57994.1 - 3.7e-41 139.8 0.1 4.5e-41 139.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Rad9 PF04139.8 CCH57995.1 - 1.7e-11 43.7 5.2 6e-10 38.6 3.6 2.2 1 1 0 1 1 1 1 Rad9 TLD PF07534.11 CCH57996.1 - 2.2e-29 102.2 0.3 3.7e-27 94.9 0.2 2.2 1 1 0 1 1 1 1 TLD AA_permease_2 PF13520.1 CCH57997.1 - 7.8e-50 169.6 46.3 9.1e-50 169.4 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCH57997.1 - 1.2e-23 83.1 35.3 1.6e-23 82.8 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin PF01024.14 CCH57997.1 - 0.0049 16.4 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Colicin pore forming domain DUF2678 PF10856.3 CCH57997.1 - 0.14 11.8 5.8 0.1 12.3 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) Ribosomal_L30_N PF08079.7 CCH57998.1 - 1.3e-21 76.3 17.6 2.2e-21 75.6 12.2 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CCH57998.1 - 4.5e-18 64.5 2.1 9.4e-18 63.5 1.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Lipoprotein_7 PF01540.11 CCH57998.1 - 0.036 13.1 2.9 0.062 12.3 2.0 1.3 1 0 0 1 1 1 0 Adhesin lipoprotein DUF1771 PF08590.5 CCH57999.1 - 2.9e-18 65.6 10.1 2.9e-18 65.6 7.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CCH57999.1 - 1.1e-15 57.6 0.2 2.6e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Smr domain HSF_DNA-bind PF00447.12 CCH58001.1 - 1.3e-35 121.6 4.1 4.1e-35 120.0 2.8 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding POX PF07526.6 CCH58001.1 - 0.0015 18.8 2.9 0.0015 18.8 2.0 2.2 2 0 0 2 2 2 1 Associated with HOX DivIC PF04977.10 CCH58001.1 - 1.4 8.4 10.0 2.2 7.8 0.1 2.7 2 1 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CCH58001.1 - 7.5 6.1 8.5 19 4.7 3.5 2.2 2 0 0 2 2 2 0 IncA protein RE_CfrBI PF09516.5 CCH58002.1 - 0.064 12.1 1.0 0.33 9.8 0.2 2.1 2 0 0 2 2 2 0 CfrBI restriction endonuclease AFT PF08731.6 CCH58003.1 - 2.5e-43 146.7 4.5 2.5e-43 146.7 3.1 3.6 4 0 0 4 4 4 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CCH58003.1 - 0.00091 18.7 4.5 0.36 10.4 0.2 2.7 2 0 0 2 2 2 2 MuDR family transposase Pkinase PF00069.20 CCH58004.1 - 5.3e-73 245.3 0.2 1.1e-72 244.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58004.1 - 3.1e-41 141.1 0.0 4.7e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58004.1 - 1.4e-05 24.1 0.0 2.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCH58004.1 - 0.024 13.9 0.2 0.097 12.0 0.2 2.0 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 CCH58005.1 - 3.6e-36 124.6 0.2 3.6e-36 124.6 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58005.1 - 1.6e-15 56.8 1.1 1.7e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCH58005.1 - 0.026 14.2 0.0 0.069 12.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ERp29_N PF07912.8 CCH58005.1 - 0.057 13.3 1.1 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 ERp29, N-terminal domain EF-hand_6 PF13405.1 CCH58005.1 - 0.12 12.3 0.3 0.84 9.6 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.20 CCH58006.1 - 3.7e-70 236.0 0.0 4.9e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58006.1 - 2e-43 148.3 0.0 2.7e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58006.1 - 4.5e-06 25.8 0.0 4.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCH58006.1 - 0.00036 19.9 0.1 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CCH58006.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCH58006.1 - 0.041 13.2 3.2 0.099 11.9 0.9 2.3 2 1 0 2 2 2 0 RIO1 family DAP3 PF10236.4 CCH58007.1 - 5.8e-74 248.8 0.9 7.3e-74 248.4 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CCH58007.1 - 5.8e-07 29.6 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCH58007.1 - 7.9e-05 22.8 0.0 0.00046 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCH58007.1 - 0.0034 17.2 0.5 0.014 15.3 0.1 2.3 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 CCH58007.1 - 0.024 14.0 0.0 0.47 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCH58007.1 - 0.033 13.8 0.1 0.37 10.4 0.1 2.9 3 1 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 CCH58007.1 - 0.048 13.0 0.1 0.93 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 CCH58007.1 - 0.05 12.5 0.0 0.087 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CCH58007.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 CCH58007.1 - 0.061 12.5 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCH58007.1 - 0.079 12.5 0.1 0.29 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 CCH58007.1 - 0.095 12.4 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 NTPase mRNA_cap_enzyme PF01331.14 CCH58008.1 - 1.5e-56 191.1 0.1 2.4e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CCH58008.1 - 1.8e-22 79.6 1.1 2.4e-21 76.0 0.8 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CCH58008.1 - 2.5e-06 27.0 0.0 3.2e-05 23.4 0.0 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PC4 PF02229.11 CCH58008.1 - 0.041 13.1 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Carbpep_Y_N PF05388.6 CCH58008.1 - 0.24 11.5 1.4 1.6 8.9 0.3 2.4 1 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide Ubiq_cyt_C_chap PF03981.7 CCH58009.1 - 1.8e-41 141.3 0.3 2.9e-41 140.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WAC_Acf1_DNA_bd PF10537.4 CCH58010.1 - 1.4e-37 127.8 5.4 2.5e-37 127.1 1.3 3.5 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCH58010.1 - 1.3e-15 56.8 1.7 2.5e-15 55.9 0.4 2.0 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 CCH58010.1 - 3.2e-08 33.1 0.2 1.1e-07 31.5 0.1 2.0 1 1 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Cyclin PF08613.6 CCH58011.1 - 3.1e-16 60.1 1.6 4.9e-16 59.4 0.4 1.8 2 0 0 2 2 2 1 Cyclin Ribosomal_L1 PF00687.16 CCH58012.1 - 5.2e-46 156.7 1.6 6.5e-46 156.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TRP PF06011.7 CCH58013.1 - 4.1e-139 463.9 34.1 4.1e-139 463.9 23.6 2.0 3 0 0 3 3 3 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCH58013.1 - 5.4e-42 143.1 0.2 5.4e-42 143.1 0.1 2.0 2 0 0 2 2 2 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCH58013.1 - 0.002 18.3 0.1 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 ML domain DUF1019 PF06254.6 CCH58013.1 - 0.086 13.0 0.1 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) TRP PF06011.7 CCH58014.1 - 1.7e-138 461.9 34.0 2.2e-138 461.5 23.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCH58014.1 - 1.4e-41 141.8 0.3 2.4e-41 141.0 0.2 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCH58014.1 - 0.004 17.4 0.1 0.0068 16.6 0.0 1.4 1 0 0 1 1 1 1 ML domain DUF1019 PF06254.6 CCH58014.1 - 0.073 13.2 0.1 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) JmjC PF02373.17 CCH58016.1 - 4.7e-13 49.3 7.7 1e-06 28.9 0.2 3.6 2 1 0 3 3 3 2 JmjC domain, hydroxylase PHD PF00628.24 CCH58016.1 - 9e-08 31.6 10.3 1.7e-07 30.8 7.1 1.5 1 0 0 1 1 1 1 PHD-finger ARID PF01388.16 CCH58016.1 - 6e-07 29.2 0.5 4.2e-06 26.5 0.4 2.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain C1_1 PF00130.17 CCH58016.1 - 0.093 12.4 0.8 0.21 11.3 0.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 CCH58016.1 - 0.22 11.6 4.2 0.56 10.3 2.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain ADK_lid PF05191.9 CCH58016.1 - 1 9.0 4.0 2.3 7.9 2.8 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid Cation_efflux PF01545.16 CCH58017.1 - 2.7e-44 151.3 5.3 3.7e-44 150.9 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family NID PF07292.8 CCH58018.1 - 0.12 12.4 3.6 3.8 7.6 0.0 3.4 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Glycos_transf_2 PF00535.21 CCH58019.1 - 7.5e-26 90.8 0.1 1.4e-25 89.9 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCH58019.1 - 2.6e-09 37.2 0.0 5.6e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCH58019.1 - 2.9e-05 23.2 0.1 4.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CCH58019.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 mRNA_triPase PF02940.10 CCH58020.1 - 9.5e-59 198.7 3.7 9.5e-59 198.7 2.6 2.4 3 0 0 3 3 3 1 mRNA capping enzyme, beta chain SIP1 PF04938.7 CCH58020.1 - 0.025 13.9 5.0 0.042 13.2 2.6 2.0 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF1758 PF05585.7 CCH58020.1 - 0.11 12.0 3.5 4.3 6.8 0.2 2.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Mis14 PF08641.7 CCH58021.1 - 2.3e-12 47.1 0.7 3.6e-12 46.5 0.5 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like TPR_MLP1_2 PF07926.7 CCH58021.1 - 0.051 13.3 0.5 0.096 12.4 0.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF2683 PF10884.3 CCH58021.1 - 0.067 13.1 0.5 0.91 9.5 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2683) ATP-synt_C PF00137.16 CCH58022.1 - 9.9e-29 99.0 28.6 1.4e-15 56.9 3.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 CCH58022.1 - 0.11 11.9 5.2 0.032 13.6 0.6 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein DUF2686 PF10887.3 CCH58022.1 - 0.17 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) KRTAP PF11759.3 CCH58022.1 - 0.77 10.0 7.9 3.4 7.9 0.7 2.2 2 0 0 2 2 2 0 Keratin-associated matrix 2TM PF13239.1 CCH58022.1 - 1.4 9.0 4.3 1.8 8.6 0.1 2.7 2 1 1 3 3 3 0 2TM domain TIP49 PF06068.8 CCH58023.1 - 1.9e-178 593.2 4.0 2.3e-178 592.9 2.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCH58023.1 - 7.5e-09 35.8 0.8 1.1e-05 25.6 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCH58023.1 - 1.8e-07 30.4 1.7 0.00029 19.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 CCH58023.1 - 1.9e-05 23.6 0.1 3.6e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CCH58023.1 - 4e-05 23.7 0.2 0.076 13.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CCH58023.1 - 4.3e-05 23.5 0.0 0.00054 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CCH58023.1 - 0.0024 17.7 0.1 3.9 7.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 CCH58023.1 - 0.0097 15.6 0.2 1.8 8.2 0.0 2.8 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCH58023.1 - 0.022 14.1 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCH58023.1 - 0.023 14.4 0.1 0.052 13.3 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 CCH58023.1 - 0.024 13.8 0.5 0.5 9.5 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCH58023.1 - 0.11 11.5 0.2 0.22 10.5 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CCH58023.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CCH58024.1 - 6.9e-37 126.9 0.0 3.6e-24 85.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58024.1 - 3.4e-16 59.0 0.0 8.2e-12 44.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase eIF-5_eIF-2B PF01873.12 CCH58026.1 - 1.4e-44 150.7 0.8 2.5e-44 149.9 0.1 1.7 2 0 0 2 2 2 1 Domain found in IF2B/IF5 Leu_zip PF15294.1 CCH58026.1 - 0.0037 16.4 9.3 0.0063 15.6 6.4 1.4 1 0 0 1 1 1 1 Leucine zipper DUF1743 PF08489.6 CCH58026.1 - 0.067 12.9 2.6 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) TF_Zn_Ribbon PF08271.7 CCH58026.1 - 0.097 12.0 0.2 0.25 10.7 0.1 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding RasGAP_C PF03836.10 CCH58027.1 - 9.9e-25 86.8 2.9 9.9e-25 86.8 2.0 3.2 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.14 CCH58027.1 - 5.9e-20 71.7 5.7 5.9e-20 71.7 3.9 4.5 4 2 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 CCH58027.1 - 2.7e-07 30.5 0.1 1.7e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 CCH58027.1 - 1.2e-06 27.5 29.0 0.0015 18.0 0.3 9.2 10 0 0 10 10 10 2 IQ calmodulin-binding motif RINGv PF12906.2 CCH58028.1 - 0.00069 19.6 8.0 0.0013 18.6 5.5 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 CCH58028.1 - 0.17 11.8 8.8 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_2 PF13639.1 CCH58028.1 - 0.49 10.2 10.4 0.1 12.4 3.4 2.3 2 0 0 2 2 2 0 Ring finger domain DUF2075 PF09848.4 CCH58030.1 - 2.9e-101 338.9 0.1 4.2e-101 338.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCH58030.1 - 7.6e-09 35.8 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH58030.1 - 2.3e-05 24.4 0.0 4.2e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCH58030.1 - 0.00019 21.6 0.0 0.00041 20.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCH58030.1 - 0.0012 18.4 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CCH58030.1 - 0.0033 17.2 0.4 0.051 13.4 0.1 2.6 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CCH58030.1 - 0.0061 16.4 0.2 0.028 14.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCH58030.1 - 0.022 13.6 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 CCH58030.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CCH58030.1 - 0.032 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 CCH58030.1 - 0.044 13.3 0.6 1.6 8.2 0.0 2.7 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 CCH58030.1 - 0.052 13.7 1.4 0.53 10.4 0.0 3.4 3 1 1 4 4 4 0 RNA helicase WD40 PF00400.27 CCH58031.1 - 2.2e-21 74.8 12.3 5e-08 32.5 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF2638 PF10937.3 CCH58031.1 - 3.6 8.6 5.5 1.4 9.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2638) RQC PF09382.5 CCH58032.1 - 1.6e-23 82.3 0.0 3.8e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 CCH58032.1 - 9e-22 77.3 0.0 2.6e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_Sgs1 PF11408.3 CCH58032.1 - 4.4e-21 74.5 0.0 2.1e-20 72.3 0.0 2.3 1 0 0 1 1 1 1 Sgs1 RecQ helicase Helicase_C PF00271.26 CCH58032.1 - 2.1e-20 72.3 0.0 4.1e-19 68.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF713 PF05218.9 CCH58033.1 - 0.079 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Ribosomal_L28 PF00830.14 CCH58034.1 - 3.4e-19 68.4 0.1 5.7e-19 67.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family DUF4108 PF13390.1 CCH58034.1 - 0.054 13.2 0.2 0.15 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) Ribosomal_L36e PF01158.13 CCH58035.1 - 4.4e-36 122.7 4.5 4.9e-36 122.6 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Cyclin_N PF00134.18 CCH58037.1 - 4.1e-34 116.8 0.0 8.3e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med4 PF10018.4 CCH58037.1 - 0.006 16.0 0.4 0.011 15.0 0.3 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 RXT2_N PF08595.6 CCH58037.1 - 0.013 15.3 3.8 0.028 14.2 2.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal ASFV_J13L PF05568.6 CCH58037.1 - 0.5 9.8 7.7 0.93 9.0 5.3 1.4 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_60s PF00428.14 CCH58037.1 - 2.1 8.7 10.7 4.7 7.6 7.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2457 PF10446.4 CCH58037.1 - 7.6 5.1 10.7 14 4.2 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rot1 PF10681.4 CCH58039.1 - 5.8e-94 313.3 0.4 7.7e-94 312.9 0.3 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VHS PF00790.14 CCH58040.1 - 5.5e-35 120.0 0.2 1.4e-34 118.7 0.1 1.7 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 CCH58040.1 - 4.7e-19 68.0 6.6 1.6e-18 66.3 4.6 1.9 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 CCH58040.1 - 0.003 16.9 7.8 0.012 15.0 2.0 3.5 2 0 0 2 2 2 1 Ubiquitin interaction motif zf-AN1 PF01428.11 CCH58040.1 - 0.046 13.5 7.4 0.1 12.4 5.1 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger zf-RING_5 PF14634.1 CCH58040.1 - 5.9 6.6 11.2 48 3.8 7.8 2.4 1 1 0 1 1 1 0 zinc-RING finger domain Autophagy_N PF03986.8 CCH58041.1 - 5.9e-40 136.3 0.9 5.9e-40 136.3 0.6 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CCH58041.1 - 8.3e-24 83.5 1.3 2.4e-23 82.0 0.2 2.4 3 0 0 3 3 3 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CCH58041.1 - 2.9e-14 51.8 2.5 6.2e-14 50.7 1.7 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal LCAT PF02450.10 CCH58042.1 - 7.4e-128 426.8 0.0 9.2e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CCH58042.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 CCH58042.1 - 0.00028 20.2 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.2 CCH58042.1 - 0.0006 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH58042.1 - 0.013 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.5 CCH58042.1 - 0.079 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF676 PF05057.9 CCH58042.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ABC2_membrane PF01061.19 CCH58043.1 - 5.1e-85 283.8 58.0 7.2e-44 149.4 14.1 2.5 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 CCH58043.1 - 1.4e-42 143.5 6.6 2.5e-38 129.8 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 CCH58043.1 - 2.2e-39 134.9 0.4 6.5e-18 65.3 0.0 3.6 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 CCH58043.1 - 7e-16 58.0 0.0 1.9e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCH58043.1 - 1.2e-07 31.3 0.0 0.00025 20.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCH58043.1 - 4.6e-06 26.5 0.2 0.041 13.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CCH58043.1 - 1.4e-05 25.1 0.6 0.00097 19.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 CCH58043.1 - 2.2e-05 24.0 1.0 0.023 14.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.2 CCH58043.1 - 3e-05 23.2 7.1 3e-05 23.2 4.9 3.9 4 0 0 4 4 2 2 ABC-2 family transporter protein DUF258 PF03193.11 CCH58043.1 - 8.1e-05 21.8 0.2 0.0054 15.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CCH58043.1 - 0.00064 19.0 0.1 0.21 10.7 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH58043.1 - 0.00098 18.6 1.6 0.0058 16.1 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CCH58043.1 - 0.0012 18.8 2.4 0.078 12.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CCH58043.1 - 0.0014 18.8 0.0 0.45 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH58043.1 - 0.0018 19.0 0.1 0.33 11.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 CCH58043.1 - 0.0021 18.3 6.6 0.015 15.5 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 CCH58043.1 - 0.0049 16.5 0.7 2.4 7.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 CCH58043.1 - 0.006 17.0 0.2 6.2 7.3 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein PduV-EutP PF10662.4 CCH58043.1 - 0.017 14.6 1.4 1.7 8.1 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CCH58043.1 - 0.025 14.2 1.4 3.7 7.1 0.1 2.6 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 CCH58043.1 - 0.026 14.1 1.0 1.2 8.7 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CCH58043.1 - 0.24 10.9 1.3 9.6 5.7 0.2 2.3 2 0 0 2 2 2 0 AAA domain Ribosomal_L23 PF00276.15 CCH58044.1 - 4.2e-20 71.4 0.0 8.4e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpb2_6 PF00562.23 CCH58045.1 - 8.3e-126 419.8 0.6 1.1e-125 419.3 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCH58045.1 - 4.9e-72 241.1 0.1 7.5e-72 240.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCH58045.1 - 9.5e-52 175.1 0.0 1.9e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCH58045.1 - 2.1e-30 104.8 0.1 5.2e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCH58045.1 - 3.1e-28 97.3 1.8 3.9e-28 97.0 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCH58045.1 - 6.3e-22 77.1 0.1 1.8e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCH58045.1 - 4.2e-17 61.8 1.8 1.1e-16 60.5 1.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DIT1_PvcA PF05141.7 CCH58046.1 - 2.6e-103 345.1 0.0 3.3e-103 344.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 CCH58047.1 - 4.4e-57 193.6 0.0 5.7e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pribosyltran PF00156.22 CCH58048.1 - 1.3e-11 44.2 0.0 2.2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 CCH58048.1 - 0.049 12.2 0.0 0.078 11.5 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase 3Beta_HSD PF01073.14 CCH58048.1 - 0.095 11.3 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peripla_BP_6 PF13458.1 CCH58048.1 - 0.12 11.6 0.0 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein Utp12 PF04003.7 CCH58049.1 - 1.3e-19 70.1 1.5 2.1e-19 69.4 1.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family IBN_N PF03810.14 CCH58050.1 - 1.8e-13 50.2 2.2 5.5e-13 48.6 0.6 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain MDM31_MDM32 PF08118.6 CCH58051.1 - 9.3e-71 238.7 23.0 5.6e-67 226.3 11.8 3.1 2 1 0 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins Actin PF00022.14 CCH58052.1 - 6.9e-26 90.5 0.0 6.4e-19 67.6 0.0 3.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCH58052.1 - 9.6e-05 21.1 0.3 0.031 12.8 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein UBA_4 PF14555.1 CCH58053.1 - 0.0082 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Metallophos PF00149.23 CCH58054.1 - 2.2e-07 30.4 2.5 7.1e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH58054.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain RhoGAP PF00620.22 CCH58055.1 - 4e-30 104.4 0.1 3.1e-20 72.3 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain BAR PF03114.13 CCH58056.1 - 2.9e-61 206.9 7.7 3.7e-61 206.5 5.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CCH58056.1 - 1e-13 50.4 0.1 2.1e-13 49.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH58056.1 - 1.1e-12 47.3 0.5 2.4e-12 46.2 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCH58056.1 - 1.3e-07 30.9 0.0 3.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pro-rich PF15240.1 CCH58056.1 - 0.00018 21.6 14.0 0.00035 20.7 9.7 1.6 1 0 0 1 1 1 1 Proline-rich ERCC4 PF02732.10 CCH58057.1 - 2.1e-20 72.9 0.2 5.1e-20 71.6 0.2 1.7 1 0 0 1 1 1 1 ERCC4 domain HTH_45 PF14947.1 CCH58057.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix HHH_3 PF12836.2 CCH58057.1 - 0.022 14.7 0.0 0.066 13.1 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif GTP_EFTU PF00009.22 CCH58058.1 - 2.6e-62 209.5 0.3 3.8e-62 209.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCH58058.1 - 4.1e-36 123.1 0.1 1.4e-35 121.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCH58058.1 - 4.1e-21 74.6 0.0 1.3e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCH58058.1 - 2.1e-13 49.9 0.0 7.4e-13 48.1 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCH58058.1 - 3.6e-12 46.2 0.9 1.4e-11 44.3 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH58058.1 - 5e-05 23.2 0.1 0.00011 22.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PX PF00787.19 CCH58059.1 - 2.2e-08 33.8 0.8 5.8e-08 32.5 0.5 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 CCH58059.1 - 3.6e-05 23.1 13.0 0.00025 20.3 9.0 2.0 1 1 0 1 1 1 1 Vps5 C terminal like Grp1_Fun34_YaaH PF01184.14 CCH58060.1 - 9.4e-64 214.5 17.1 1.2e-63 214.2 11.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_60s PF00428.14 CCH58061.1 - 3.2e-23 81.9 15.4 3.6e-23 81.7 10.7 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DLIC PF05783.6 CCH58061.1 - 0.15 10.6 0.9 0.16 10.6 0.6 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Treacle PF03546.9 CCH58061.1 - 2.3 6.9 13.0 1.2 7.8 7.2 1.6 1 1 1 2 2 2 0 Treacher Collins syndrome protein Treacle Mito_carr PF00153.22 CCH58062.1 - 5.2e-60 199.1 2.7 1.9e-20 72.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 CCH58064.1 - 4.3e-13 48.6 0.0 8.3e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58064.1 - 8.2e-12 44.9 0.0 1.9e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58064.1 - 3.3e-07 30.0 0.0 8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM117 PF15388.1 CCH58064.1 - 9.9e-05 21.7 10.6 0.012 14.8 3.0 2.1 2 0 0 2 2 2 2 Protein Family FAM117 Limkain-b1 PF11608.3 CCH58064.1 - 0.018 14.7 0.1 0.069 12.9 0.0 2.2 1 1 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.1 CCH58064.1 - 0.044 13.5 0.0 0.093 12.5 0.0 1.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FoP_duplication PF13865.1 CCH58064.1 - 5 7.6 34.2 0.62 10.5 11.2 3.7 2 2 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Afi1 PF07792.7 CCH58065.1 - 1e-16 61.2 0.1 1e-16 61.2 0.1 3.6 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CCH58065.1 - 6.7e-08 32.2 6.4 6.7e-08 32.2 2.7 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis TPP_enzyme_N PF02776.13 CCH58066.1 - 4.1e-22 78.4 0.0 8.1e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCH58066.1 - 5.1e-18 65.1 0.0 9.6e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCH58066.1 - 1.7e-12 47.1 0.0 3.5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4639 PF15479.1 CCH58066.1 - 0.19 10.3 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) AIRC PF00731.15 CCH58067.1 - 6.1e-66 220.3 1.7 1e-65 219.6 1.2 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CCH58067.1 - 7.4e-57 191.4 0.0 1.3e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCH58067.1 - 1.9e-07 31.0 0.0 3.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CCH58067.1 - 6e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 CCH58067.1 - 0.00077 18.3 0.0 0.0051 15.6 0.0 2.2 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon 2-Hacid_dh_C PF02826.14 CCH58067.1 - 0.0046 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CCH58067.1 - 0.019 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 CCH58067.1 - 0.036 14.2 0.2 12 6.1 0.0 2.5 1 1 1 2 2 2 0 CoA binding domain TrkA_N PF02254.13 CCH58067.1 - 0.15 12.1 0.9 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain RhoGAP PF00620.22 CCH58068.1 - 4.8e-42 143.1 2.0 4.8e-42 143.1 1.4 2.4 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CCH58068.1 - 3.5e-13 49.3 28.6 2.3e-06 27.5 9.2 2.7 2 0 0 2 2 2 2 LIM domain CCDC155 PF14662.1 CCH58068.1 - 0.0008 19.0 3.0 0.0018 17.8 2.1 1.6 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 V_ATPase_I PF01496.14 CCH58068.1 - 0.0019 16.1 3.9 0.0031 15.4 2.7 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PDZ_assoc PF10600.4 CCH58068.1 - 0.0056 16.9 1.2 0.029 14.6 0.2 2.7 2 0 0 2 2 2 1 PDZ-associated domain of NMDA receptors APG6 PF04111.7 CCH58068.1 - 0.0086 15.1 6.3 0.023 13.7 4.4 1.7 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF3086 PF11285.3 CCH58068.1 - 0.068 11.9 0.7 0.17 10.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) IncA PF04156.9 CCH58068.1 - 0.31 10.5 5.0 0.32 10.5 1.8 2.3 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 CCH58068.1 - 2.5 7.6 5.7 3.4 7.2 2.4 2.0 1 1 0 1 1 1 0 Septum formation initiator Pyr_redox_3 PF13738.1 CCH58069.1 - 1e-05 25.7 0.0 0.035 14.1 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCH58069.1 - 8.4e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCH58069.1 - 0.0028 17.4 0.0 0.0098 15.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 CCH58069.1 - 0.023 14.9 0.0 6.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 CCH58069.1 - 0.035 13.9 0.0 0.25 11.2 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCH58069.1 - 0.11 12.9 0.1 19 5.7 0.1 3.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCH58069.1 - 0.13 11.3 0.0 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lipase_GDSL PF00657.17 CCH58070.1 - 1.4e-19 70.8 0.0 1.7e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 CCH58070.1 - 1.3e-17 64.4 0.0 1.6e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BCS1_N PF08740.6 CCH58071.1 - 4.4e-49 166.6 0.2 7.8e-49 165.8 0.1 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCH58071.1 - 6.2e-23 81.4 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCH58071.1 - 4.1e-06 27.6 0.0 1.1e-05 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH58071.1 - 0.00038 20.3 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH58071.1 - 0.001 19.1 0.0 0.0032 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CCH58071.1 - 0.0015 18.6 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCH58071.1 - 0.0015 17.6 0.0 0.0028 16.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCH58071.1 - 0.0019 18.3 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH58071.1 - 0.0021 18.3 0.0 0.0066 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCH58071.1 - 0.0026 16.7 0.0 0.0048 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CCH58071.1 - 0.0028 17.3 0.0 0.01 15.5 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCH58071.1 - 0.0031 16.9 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCH58071.1 - 0.0055 16.6 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCH58071.1 - 0.014 14.8 0.0 0.05 13.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCH58071.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 CCH58071.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 CCH58071.1 - 0.018 14.6 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCH58071.1 - 0.023 14.8 0.0 0.076 13.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase NACHT PF05729.7 CCH58071.1 - 0.027 14.1 0.0 0.27 10.8 0.0 2.5 2 1 1 3 3 3 0 NACHT domain AAA_19 PF13245.1 CCH58071.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.7 1 1 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 CCH58071.1 - 0.043 14.1 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCH58071.1 - 0.043 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 CCH58071.1 - 0.049 12.7 0.0 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 KaiC Miro PF08477.8 CCH58071.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 CCH58071.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CCH58071.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.7 CCH58072.1 - 2.7e-24 85.0 2.8 2.7e-24 85.0 2.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH58072.1 - 1.2e-16 60.4 0.0 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCH58072.1 - 4.4e-06 25.9 0.1 7.3e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CCH58072.1 - 0.037 13.8 0.1 0.055 13.2 0.1 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CCH58072.1 - 0.11 12.0 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain YTH PF04146.10 CCH58073.1 - 5.4e-41 139.4 0.5 1.3e-40 138.2 0.4 1.7 1 0 0 1 1 1 1 YT521-B-like domain COQ7 PF03232.8 CCH58074.1 - 8.4e-74 246.7 0.0 1e-73 246.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 EF-hand_7 PF13499.1 CCH58075.1 - 1e-27 96.0 14.1 2.6e-14 53.0 0.5 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CCH58075.1 - 3.1e-26 88.6 5.9 1.3e-07 30.3 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CCH58075.1 - 4.6e-24 82.0 1.9 2.2e-06 27.0 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CCH58075.1 - 6.8e-20 69.4 4.9 1e-05 24.6 0.2 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CCH58075.1 - 2.3e-19 68.7 4.8 2.4e-07 30.2 0.2 3.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 CCH58075.1 - 3e-06 26.8 5.8 0.22 11.2 0.0 3.5 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCH58075.1 - 6.7e-05 22.7 0.3 0.0016 18.3 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CCH58075.1 - 0.00057 19.9 0.8 0.029 14.3 0.6 3.1 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CCH58075.1 - 0.0017 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_10 PF14788.1 CCH58075.1 - 0.14 11.8 0.3 14 5.4 0.0 2.7 2 0 0 2 2 2 0 EF hand GPP34 PF05719.6 CCH58076.1 - 4.2e-46 157.6 0.0 5.2e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.23 CCH58077.1 - 2.7e-79 267.1 6.1 5.8e-79 266.0 4.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 RAI1 PF08652.6 CCH58078.1 - 0.0026 17.5 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease RBFA PF02033.13 CCH58078.1 - 0.086 12.8 0.0 0.27 11.2 0.0 1.9 1 1 0 1 1 1 0 Ribosome-binding factor A FHA PF00498.21 CCH58080.1 - 7.9e-05 22.7 0.1 7.9e-05 22.7 0.1 2.5 3 0 0 3 3 3 1 FHA domain Aldo_ket_red PF00248.16 CCH58081.1 - 5.1e-49 166.6 0.0 6.2e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BHD_3 PF10405.4 CCH58081.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.8 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 Aldo_ket_red PF00248.16 CCH58082.1 - 1.7e-48 164.9 0.0 2.2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2800 PF10926.3 CCH58082.1 - 0.057 12.5 0.1 0.93 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) zf-HIT PF04438.11 CCH58083.1 - 2.4e-09 36.6 11.0 4e-09 35.9 7.6 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.8 CCH58083.1 - 3.7 5.1 8.9 5 4.6 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 V-ATPase_G PF03179.10 CCH58084.1 - 7e-31 106.6 12.4 7.8e-31 106.4 8.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Prominin PF05478.6 CCH58084.1 - 0.18 9.3 1.2 0.19 9.2 0.8 1.0 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.3 CCH58084.1 - 0.23 10.6 17.9 0.039 13.1 6.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 CCH58084.1 - 0.34 10.7 17.4 0.064 13.0 5.7 2.0 1 1 0 2 2 2 0 ATP synthase B/B' CF(0) Mitofilin PF09731.4 CCH58084.1 - 0.63 8.6 12.0 0.76 8.3 8.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Atrophin-1 PF03154.10 CCH58084.1 - 1.2 7.1 4.3 1.3 7.1 3.0 1.0 1 0 0 1 1 1 0 Atrophin-1 family GA PF01468.12 CCH58084.1 - 6.9 6.9 10.1 0.63 10.2 2.9 2.4 2 1 1 3 3 3 0 GA module RRF PF01765.14 CCH58085.1 - 1.3e-34 119.0 8.0 2e-34 118.4 5.5 1.3 1 0 0 1 1 1 1 Ribosome recycling factor NifW PF03206.9 CCH58085.1 - 0.0061 16.6 1.5 0.014 15.4 0.2 2.0 2 0 0 2 2 2 1 Nitrogen fixation protein NifW FCH PF00611.18 CCH58085.1 - 1.9 8.7 8.2 0.95 9.6 0.4 3.0 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain ABC_tran_2 PF12848.2 CCH58085.1 - 3.9 7.3 9.6 1.7 8.5 2.6 2.5 2 2 0 2 2 2 0 ABC transporter RNB PF00773.14 CCH58086.1 - 6.6e-59 199.8 2.4 6.6e-59 199.8 1.7 3.7 4 0 0 4 4 4 1 RNB domain OB_RNB PF08206.6 CCH58086.1 - 0.00068 19.0 0.0 0.43 10.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain SseC PF04888.7 CCH58086.1 - 6.2 6.0 8.3 13 4.9 5.8 1.5 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Claudin_3 PF06653.6 CCH58087.1 - 3.4 7.3 13.3 0.64 9.7 1.3 2.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Pyridoxal_deC PF00282.14 CCH58088.1 - 4.7e-22 77.9 0.0 7e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CCH58088.1 - 1.9e-05 23.9 0.0 3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CCH58088.1 - 0.00057 18.7 0.0 0.0014 17.4 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V FRG2 PF15315.1 CCH58089.1 - 0.033 14.1 12.2 0.05 13.5 8.5 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 SAPS PF04499.10 CCH58089.1 - 0.16 10.5 1.1 0.17 10.5 0.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4614 PF15391.1 CCH58089.1 - 0.37 10.5 5.1 0.57 9.9 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) BRF1 PF07741.8 CCH58089.1 - 0.6 10.3 8.9 0.99 9.6 6.2 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Atg14 PF10186.4 CCH58089.1 - 0.95 8.3 12.9 1.2 7.9 8.9 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 CCH58089.1 - 9.2 5.1 11.1 12 4.7 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FA_hydroxylase PF04116.8 CCH58090.1 - 8.1e-17 61.6 9.5 8.1e-17 61.6 6.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TRAUB PF08164.7 CCH58091.1 - 2.3e-26 91.7 0.1 2.3e-26 91.7 0.0 3.0 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CCH58091.1 - 3.3e-25 88.7 3.5 3.3e-25 88.7 2.5 2.3 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor AA_kinase PF00696.23 CCH58092.1 - 1.3e-35 123.1 0.2 2.7e-35 122.0 0.1 1.6 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 CCH58092.1 - 1.6e-18 66.1 0.1 5.5e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 PUA domain Nucleotid_trans PF03407.11 CCH58092.1 - 0.07 12.9 0.2 0.37 10.5 0.1 2.0 1 1 1 2 2 2 0 Nucleotide-diphospho-sugar transferase HAD_2 PF13419.1 CCH58092.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Gal4_dimer PF03902.8 CCH58092.1 - 0.14 12.0 1.1 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Gal4-like dimerisation domain CPSF_A PF03178.10 CCH58093.1 - 2.4e-77 260.1 0.3 8.9e-77 258.3 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region Nop14 PF04147.7 CCH58093.1 - 8.5 4.1 23.9 1.6 6.5 1.4 2.1 2 0 0 2 2 2 0 Nop14-like family PIG-F PF06699.6 CCH58094.1 - 5.8e-40 137.2 21.3 3.6e-39 134.6 14.8 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Claudin_3 PF06653.6 CCH58094.1 - 0.0097 15.6 9.2 0.0097 15.6 6.4 1.5 1 1 0 1 1 1 1 Tight junction protein, Claudin-like Flp_Fap PF04964.9 CCH58094.1 - 0.046 13.3 0.6 0.097 12.2 0.4 1.5 1 0 0 1 1 1 0 Flp/Fap pilin component Zn_clus PF00172.13 CCH58095.1 - 2.2e-07 30.6 8.6 4.7e-07 29.6 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med6 PF04934.9 CCH58096.1 - 6.7e-47 158.5 0.0 8.5e-47 158.2 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 CCH58097.1 - 2.1e-17 62.7 0.7 3.2e-17 62.1 0.5 1.3 1 0 0 1 1 1 1 IGR protein motif Profilin PF00235.14 CCH58097.1 - 0.063 13.3 0.0 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Profilin F-box-like PF12937.2 CCH58098.1 - 0.00031 20.3 0.3 0.00081 19.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like FNIP PF05725.7 CCH58098.1 - 0.23 11.4 4.0 1.3 9.0 0.1 3.6 3 1 0 3 3 3 0 FNIP Repeat MIR PF02815.14 CCH58099.1 - 1.5e-08 34.4 0.1 3.7e-08 33.1 0.1 1.5 2 0 0 2 2 2 1 MIR domain PMT PF02366.13 CCH58099.1 - 0.00028 20.3 16.6 0.00085 18.7 11.5 1.8 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MerT PF02411.10 CCH58099.1 - 3.9 7.3 8.7 3.1 7.6 0.0 3.5 3 1 0 3 3 3 0 MerT mercuric transport protein GAGA_bind PF06217.7 CCH58100.1 - 0.11 12.5 7.9 0.12 12.3 5.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_P_p30 PF01876.11 CCH58101.1 - 2.5e-43 146.8 0.2 3.4e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 BSD PF03909.12 CCH58103.1 - 1.5e-26 91.8 5.9 2.8e-14 52.5 0.3 3.0 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CCH58103.1 - 4.8e-23 80.5 1.0 3.4e-22 77.8 0.1 2.4 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DUF3349 PF11829.3 CCH58103.1 - 0.07 13.5 0.6 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Brix PF04427.13 CCH58104.1 - 1e-58 198.1 4.7 1.6e-58 197.5 3.2 1.3 1 0 0 1 1 1 1 Brix domain FYVE PF01363.16 CCH58105.1 - 6.4e-21 74.0 5.2 6.4e-21 74.0 3.6 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CCH58105.1 - 1.4e-08 34.4 2.7 1.4e-08 34.4 1.9 3.7 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.1 CCH58105.1 - 0.0098 15.5 2.3 0.0098 15.5 1.6 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-DHHC PF01529.15 CCH58105.1 - 0.017 14.4 5.9 0.19 11.1 3.7 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-C3HC4_2 PF13923.1 CCH58105.1 - 0.02 14.9 3.6 0.02 14.9 2.5 4.2 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) PilI PF10623.4 CCH58105.1 - 0.38 10.7 3.6 1.6 8.7 0.0 2.6 3 0 0 3 3 3 0 Plasmid conjugative transfer protein PilI DUF3133 PF11331.3 CCH58105.1 - 0.49 9.9 4.0 1.3 8.6 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zf-rbx1 PF12678.2 CCH58105.1 - 4.8 7.3 18.0 0.11 12.6 1.6 3.7 3 1 0 3 3 3 0 RING-H2 zinc finger FYVE_2 PF02318.11 CCH58105.1 - 5.6 6.8 12.5 0.51 10.2 4.6 2.3 2 1 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.1 CCH58105.1 - 6.6 6.5 28.2 0.21 11.3 2.1 4.2 4 1 0 4 4 4 0 zinc-RING finger domain Ins_P5_2-kin PF06090.7 CCH58106.1 - 2.1e-34 119.0 3.4 3.5e-34 118.2 2.4 1.4 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase P4Ha_N PF08336.6 CCH58106.1 - 0.082 12.7 0.2 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Methyltransf_23 PF13489.1 CCH58107.1 - 1.2e-17 64.1 0.0 1.8e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH58107.1 - 7.9e-14 51.9 0.0 1.9e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH58107.1 - 3.3e-11 43.0 0.7 6.3e-11 42.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH58107.1 - 6.8e-10 39.3 0.0 1.5e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH58107.1 - 3.2e-09 37.3 0.0 7.3e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH58107.1 - 3.3e-09 36.2 0.0 5.8e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CCH58107.1 - 3.5e-07 30.5 0.0 7.9e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH58107.1 - 0.069 12.5 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DUF4435 PF14491.1 CCH58107.1 - 0.41 10.4 9.9 0.33 10.7 2.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4435) ECR1_N PF14382.1 CCH58108.1 - 7.9e-11 41.0 0.2 1.7e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CCH58108.1 - 0.0067 16.3 0.0 0.081 12.8 0.0 2.6 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 Cyclin PF08613.6 CCH58109.1 - 1.7e-10 41.4 0.9 3e-10 40.6 0.6 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCH58109.1 - 4e-07 29.6 0.4 6.3e-07 29.0 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain HIM1 PF08732.5 CCH58110.1 - 1.9e-35 122.1 9.6 5.2e-35 120.6 6.6 1.7 1 1 0 1 1 1 1 HIM1 Scs3p PF10261.4 CCH58111.1 - 1.5e-30 105.9 19.4 7.8e-30 103.6 13.5 2.1 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 CCH58111.1 - 0.00014 21.5 2.3 0.00014 21.5 1.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily Orai-1 PF07856.7 CCH58111.1 - 0.11 12.1 1.8 0.23 11.0 1.3 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF4029 PF13221.1 CCH58111.1 - 8.8 6.7 13.2 0.26 11.7 3.8 2.3 2 2 0 2 2 2 0 Protein of unknown function (DUF4029) Prenyltrans PF00432.16 CCH58112.1 - 3.4e-26 90.4 0.3 5.8e-08 32.1 0.0 4.7 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCH58112.1 - 5.3e-22 78.3 0.0 1.3e-11 44.8 0.0 4.8 4 1 1 5 5 5 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCH58112.1 - 1.1e-21 76.8 0.0 4e-17 62.2 0.1 4.6 3 2 2 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 CCH58112.1 - 0.0081 15.3 0.2 1.1 8.4 0.0 3.2 1 1 1 3 3 3 1 Pectic acid lyase HCV_NS4a PF01006.15 CCH58112.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a DASH_Dad4 PF08650.5 CCH58113.1 - 1.1e-25 89.3 0.3 1.2e-25 89.2 0.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 CagA PF03507.8 CCH58113.1 - 0.025 14.4 0.0 0.026 14.3 0.0 1.1 1 0 0 1 1 1 0 CagA exotoxin COG6 PF06419.6 CCH58113.1 - 0.07 11.2 0.4 0.076 11.1 0.3 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 SNARE PF05739.14 CCH58113.1 - 0.13 11.9 0.6 0.2 11.3 0.4 1.3 1 0 0 1 1 1 0 SNARE domain Oxysterol_BP PF01237.13 CCH58114.1 - 1.2e-95 319.9 0.8 2.7e-95 318.8 0.6 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CCH58114.1 - 7.3e-31 106.1 0.5 2.2e-30 104.5 0.3 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CCH58114.1 - 5.4 7.2 9.7 1.3 9.3 2.5 3.4 2 1 0 2 2 2 0 Pleckstrin homology domain Asparaginase PF00710.15 CCH58115.1 - 6.9e-72 241.9 0.0 8.5e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ribosomal_L19 PF01245.15 CCH58115.1 - 0.01 15.6 0.0 5 6.9 0.0 3.3 3 1 0 3 3 3 0 Ribosomal protein L19 Abhydrolase_6 PF12697.2 CCH58116.1 - 2.2e-14 53.9 0.0 3.6e-14 53.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH58116.1 - 2.3e-08 33.8 0.0 3.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCH58116.1 - 1.9e-07 30.9 0.0 3.4e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 CCH58116.1 - 0.0041 15.4 0.1 0.34 9.1 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II VirJ PF06057.6 CCH58116.1 - 0.015 15.1 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) PGAP1 PF07819.8 CCH58116.1 - 0.065 12.8 0.5 0.12 11.9 0.3 1.6 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CCH58116.1 - 0.096 12.3 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) PBP PF01161.15 CCH58117.1 - 6.6e-11 42.2 0.1 1.2e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATP-synt_E PF05680.7 CCH58118.1 - 4e-15 55.5 0.0 4e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain SpoIIE PF07228.7 CCH58119.1 - 2.9e-29 102.1 0.0 4.1e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CCH58119.1 - 1.2e-06 28.1 0.2 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCH58119.1 - 2.2e-06 27.2 0.0 4.3e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C MIF4G PF02854.14 CCH58120.1 - 2e-47 161.2 38.1 3.4e-21 75.6 4.2 4.3 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CCH58120.1 - 2.6e-17 63.1 22.9 2.6e-17 63.1 15.9 2.8 1 1 1 2 2 2 1 Up-frameshift suppressor 2 Nop14 PF04147.7 CCH58120.1 - 4.4 5.1 41.4 2.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Nop14-like family WD40 PF00400.27 CCH58121.1 - 1.3e-11 43.8 16.5 0.047 13.5 0.2 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF4623 PF15416.1 CCH58121.1 - 0.024 13.0 0.0 0.059 11.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4623) Pkinase PF00069.20 CCH58122.1 - 3.8e-48 163.9 0.1 8.3e-48 162.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CCH58122.1 - 2.9e-34 117.7 2.7 1.4e-33 115.5 1.9 2.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CCH58122.1 - 9.3e-27 93.7 0.0 8.1e-25 87.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 CCH58122.1 - 3.8e-05 23.0 0.0 0.18 11.3 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 CCH58122.1 - 0.0029 17.0 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 CCH58122.1 - 0.033 13.2 0.1 0.067 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH58122.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Swi5 PF07061.6 CCH58123.1 - 3.9e-17 61.8 3.8 4.7e-17 61.5 2.7 1.2 1 0 0 1 1 1 1 Swi5 HTH_DeoR PF08220.7 CCH58123.1 - 0.0062 16.0 0.6 0.015 14.8 0.1 1.9 2 0 0 2 2 2 1 DeoR-like helix-turn-helix domain TBPIP PF07106.8 CCH58123.1 - 0.049 13.1 5.7 0.056 12.9 4.0 1.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2935 PF11155.3 CCH58123.1 - 0.053 13.6 1.5 0.059 13.4 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) HTH_28 PF13518.1 CCH58123.1 - 0.057 13.4 0.1 8 6.5 0.0 2.7 1 1 1 2 2 2 0 Helix-turn-helix domain CCDC92 PF14916.1 CCH58123.1 - 0.079 12.5 1.8 0.11 12.0 1.0 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function YlqD PF11068.3 CCH58123.1 - 0.089 12.8 2.8 0.1 12.6 2.0 1.0 1 0 0 1 1 1 0 YlqD protein DUF342 PF03961.8 CCH58123.1 - 0.25 9.6 4.9 0.26 9.6 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Viral_P18 PF04521.8 CCH58123.1 - 1.3 8.4 4.0 2.2 7.7 0.7 2.0 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HALZ PF02183.13 CCH58123.1 - 1.7 8.3 6.6 0.3 10.8 1.0 2.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper GRAM PF02893.15 CCH58124.1 - 1.5e-18 66.0 0.1 3.5e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 GRAM domain BRE1 PF08647.6 CCH58125.1 - 0.093 12.7 3.1 0.13 12.2 1.9 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF2731 PF10806.3 CCH58126.1 - 1.4e-28 99.6 1.3 1.4e-28 99.6 0.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2731) STE PF02200.11 CCH58127.1 - 7e-60 199.9 4.1 1.5e-59 198.8 2.9 1.6 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.9 CCH58128.1 - 3.5e-76 256.5 2.5 6.4e-76 255.6 1.7 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 GAGA_bind PF06217.7 CCH58128.1 - 9.7 6.0 13.0 16 5.3 9.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ipi1_N PF12333.3 CCH58129.1 - 1.3e-25 89.2 0.2 4.1e-25 87.7 0.2 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 CCH58129.1 - 0.009 16.0 0.0 0.089 12.9 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat Lambda_Bor PF06291.6 CCH58129.1 - 0.096 12.6 0.0 0.36 10.7 0.0 1.9 2 0 0 2 2 2 0 Bor protein RRM_1 PF00076.17 CCH58130.1 - 1.6e-25 88.5 0.0 3.7e-16 58.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58130.1 - 3.4e-18 65.4 0.0 1.5e-10 40.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58130.1 - 2.2e-14 53.0 0.0 2.1e-11 43.4 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCH58130.1 - 5.5e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCH58130.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SNF2_N PF00176.18 CCH58131.1 - 6.1e-76 255.0 0.3 6.1e-76 255.0 0.2 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH58131.1 - 1.8e-14 53.3 0.0 6.9e-14 51.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 CCH58131.1 - 1.8e-13 50.0 0.7 1.8e-13 50.0 0.5 3.0 3 0 0 3 3 3 1 HSA DEAD PF00270.24 CCH58131.1 - 2.7e-07 30.2 0.0 1.9e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase IBN_N PF03810.14 CCH58132.1 - 0.54 10.2 8.4 0.069 13.0 0.5 3.7 4 0 0 4 4 4 0 Importin-beta N-terminal domain MMR_HSR1 PF01926.18 CCH58133.1 - 2.3e-15 56.5 0.5 5e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCH58133.1 - 1.4e-07 31.5 1.8 0.0012 18.7 0.0 2.7 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCH58133.1 - 5.2e-07 28.9 0.1 3.1e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCH58133.1 - 8.5e-06 25.3 0.1 3.6e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CCH58133.1 - 1.1e-05 24.6 0.1 1.7e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 CCH58133.1 - 7.4e-05 22.0 0.3 0.0002 20.6 0.2 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 CCH58133.1 - 8.5e-05 21.7 1.4 0.00013 21.1 0.1 1.9 2 0 0 2 2 2 1 Septin Gtr1_RagA PF04670.7 CCH58133.1 - 0.00033 19.8 0.5 0.0005 19.2 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CCH58133.1 - 0.00045 19.5 0.1 0.0008 18.7 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 CCH58133.1 - 0.00054 19.4 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ras PF00071.17 CCH58133.1 - 0.00078 18.8 0.1 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH58133.1 - 0.0046 17.4 2.9 0.015 15.7 0.4 2.6 2 1 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 CCH58133.1 - 0.0059 16.3 1.0 0.012 15.3 0.0 1.9 2 1 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 CCH58133.1 - 0.0069 16.0 1.0 0.0094 15.6 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CCH58133.1 - 0.0071 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF3688 PF12461.3 CCH58133.1 - 0.013 15.8 2.1 0.013 15.8 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3688) AAA_10 PF12846.2 CCH58133.1 - 0.015 14.7 0.1 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 CCH58133.1 - 0.046 14.0 0.2 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 CCH58133.1 - 0.049 13.1 1.1 0.089 12.2 0.1 2.0 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCH58133.1 - 0.067 13.3 0.4 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Gar1 PF04410.9 CCH58134.1 - 1.1e-44 151.5 0.2 1.1e-44 151.5 0.1 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Ribosomal_S15 PF00312.17 CCH58135.1 - 1e-23 82.8 1.1 1.9e-23 81.9 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 KRAP_IP3R_bind PF14722.1 CCH58135.1 - 0.041 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain ING PF12998.2 CCH58136.1 - 4.8e-12 46.0 5.5 4.8e-12 46.0 3.8 2.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCH58136.1 - 6.5e-10 38.5 10.4 1.4e-09 37.4 7.2 1.6 1 0 0 1 1 1 1 PHD-finger DUF4112 PF13430.1 CCH58137.1 - 8.8e-25 86.6 0.2 1.3e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) EcsC PF12787.2 CCH58137.1 - 0.0024 17.3 0.2 0.037 13.4 0.1 2.4 2 1 1 3 3 3 1 EcsC protein family tRNA-synt_1d PF00750.14 CCH58138.1 - 3.5e-90 302.3 2.9 4.7e-90 301.9 2.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCH58138.1 - 3.3e-26 91.5 0.3 9.2e-26 90.1 0.2 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CCH58138.1 - 0.00095 19.6 0.0 0.0026 18.2 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Sugar_tr PF00083.19 CCH58139.1 - 2.7e-158 527.2 31.9 3.2e-158 527.0 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58139.1 - 2.8e-31 108.5 31.1 9.4e-30 103.4 11.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58139.1 - 4.6e-07 28.4 4.6 6.8e-07 27.8 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCH58139.1 - 0.13 10.3 5.6 0.026 12.6 1.0 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 CCH58140.1 - 5.4e-164 546.0 35.6 6.3e-164 545.8 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58140.1 - 1.6e-29 102.7 30.6 4.3e-29 101.3 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58140.1 - 0.00077 17.7 2.0 0.00077 17.7 1.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCH58141.1 - 6.3e-150 499.6 22.8 7.2e-150 499.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58141.1 - 4.2e-31 107.9 24.7 8.4e-28 97.0 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58142.1 - 1.8e-153 511.3 29.0 2e-153 511.1 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58142.1 - 1.4e-29 102.9 28.5 1.1e-25 90.1 11.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2868 PF11067.3 CCH58142.1 - 0.098 11.7 0.2 0.2 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Sugar_tr PF00083.19 CCH58143.1 - 2.6e-163 543.7 32.9 3e-163 543.5 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58143.1 - 8e-34 116.8 25.5 2.2e-33 115.4 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58143.1 - 0.00051 18.3 2.8 0.00086 17.6 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.11 CCH58143.1 - 0.49 9.4 3.2 0.49 9.4 0.6 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Sugar_tr PF00083.19 CCH58144.1 - 1.5e-152 508.3 30.3 1.7e-152 508.1 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58144.1 - 1.6e-31 109.2 41.7 1.1e-26 93.4 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58144.1 - 2.4e-05 22.7 1.4 2.4e-05 22.7 1.0 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCH58145.1 - 1.5e-162 541.3 33.0 1.7e-162 541.0 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58145.1 - 5.6e-32 110.8 28.0 1.3e-31 109.5 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 CCH58145.1 - 0.14 11.2 2.4 2.9 6.9 0.7 2.9 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family MFS_3 PF05977.8 CCH58145.1 - 0.87 7.6 8.2 0.063 11.3 2.2 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 CCH58146.1 - 4.6e-155 516.6 34.5 5.4e-155 516.3 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58146.1 - 7.3e-33 113.7 31.5 5.1e-29 101.1 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58146.1 - 0.00018 19.8 1.9 0.00033 18.9 1.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCH58147.1 - 1.5e-156 521.5 33.2 1.7e-156 521.3 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58147.1 - 3.5e-32 111.4 32.9 3.9e-29 101.4 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58147.1 - 0.00027 19.2 1.6 0.00044 18.5 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCH58148.1 - 3.6e-164 546.6 33.4 4.1e-164 546.4 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58148.1 - 4.4e-34 117.7 28.8 1.8e-31 109.1 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCH58148.1 - 0.00051 18.5 9.2 0.00051 18.5 6.4 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 CCH58148.1 - 0.0019 16.4 1.5 0.0019 16.4 1.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATP1G1_PLM_MAT8 PF02038.11 CCH58148.1 - 0.0055 15.6 2.8 0.16 11.0 0.8 3.1 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family MFS_3 PF05977.8 CCH58148.1 - 0.13 10.3 5.3 0.035 12.2 1.2 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 CCH58149.1 - 8.5e-153 509.1 33.5 9.8e-153 508.9 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58149.1 - 1.5e-28 99.5 30.8 8.2e-25 87.2 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58149.1 - 5.2e-05 21.6 1.7 9.1e-05 20.8 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) E1-E2_ATPase PF00122.15 CCH58149.1 - 0.047 12.7 0.4 0.11 11.4 0.3 1.6 1 0 0 1 1 1 0 E1-E2 ATPase ATP1G1_PLM_MAT8 PF02038.11 CCH58149.1 - 0.62 9.1 10.2 0.13 11.2 0.8 3.3 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family Sugar_tr PF00083.19 CCH58150.1 - 1.4e-169 564.4 35.9 1.6e-169 564.2 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58150.1 - 2.1e-31 108.9 39.6 2.4e-26 92.3 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1 PF08622.5 CCH58151.1 - 1.1e-119 399.2 19.2 3.6e-118 394.2 13.3 2.5 1 1 0 1 1 1 1 Svf1-like DUF3235 PF11574.3 CCH58151.1 - 0.0013 18.8 0.7 0.066 13.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3235) CENP-B_dimeris PF09026.5 CCH58151.1 - 4.9 7.4 14.3 2.3 8.4 7.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sec23_trunk PF04811.10 CCH58152.1 - 7.1e-48 163.0 0.1 1.2e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 CCH58152.1 - 2.1e-12 46.4 5.3 4.4e-12 45.3 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCH58152.1 - 2.8e-10 40.5 0.0 9.1e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CCH58152.1 - 6.2e-06 25.5 0.1 4.2e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 CCH58152.1 - 0.00018 21.1 0.0 0.00044 19.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat FAT PF02259.18 CCH58153.1 - 1.8e-69 234.3 6.7 3.6e-69 233.4 4.7 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CCH58153.1 - 1.4e-37 129.4 0.4 1.4e-37 129.4 0.2 3.5 4 0 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CCH58153.1 - 7.6e-05 22.0 0.0 0.00023 20.5 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 CCH58153.1 - 0.0021 17.6 0.7 0.024 14.2 0.1 2.8 2 0 0 2 2 2 1 TPR repeat PGP_phosphatase PF09419.5 CCH58154.1 - 1.3e-63 213.2 0.0 1.5e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CCH58154.1 - 8.7e-05 22.1 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Rep-A_N PF04057.7 CCH58155.1 - 0.018 14.8 0.4 0.057 13.2 0.0 2.1 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Pkinase PF00069.20 CCH58156.1 - 1.1e-69 234.4 0.0 1.9e-69 233.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58156.1 - 3.9e-50 170.3 0.0 6.7e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58156.1 - 3.6e-07 29.4 0.0 2.1e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCH58156.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PQ-loop PF04193.9 CCH58158.1 - 4.4e-31 106.2 20.4 1.6e-17 62.7 2.0 2.9 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 CCH58158.1 - 0.083 12.7 15.2 0.44 10.4 0.5 2.6 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 CCH58158.1 - 0.11 13.0 0.2 0.11 13.0 0.1 3.6 2 2 1 3 3 3 0 ER lumen protein retaining receptor Herpes_LMP1 PF05297.6 CCH58158.1 - 0.53 9.1 2.3 0.97 8.2 1.6 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3784 PF12650.2 CCH58158.1 - 7.8 6.5 15.1 1.7 8.6 0.8 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) PX PF00787.19 CCH58159.1 - 2.1e-14 53.2 0.2 3.1e-14 52.7 0.1 1.4 1 0 0 1 1 1 1 PX domain Reo_sigmaC PF04582.7 CCH58160.1 - 2.7e-05 23.5 23.5 0.00022 20.5 5.0 5.5 1 1 5 6 6 6 5 Reovirus sigma C capsid protein Filament PF00038.16 CCH58160.1 - 0.037 13.5 132.3 0.13 11.6 24.2 4.2 2 1 2 4 4 4 0 Intermediate filament protein Myosin_tail_1 PF01576.14 CCH58160.1 - 4.8 4.7 147.1 0.0054 14.5 37.7 3.9 1 1 2 3 3 3 0 Myosin tail VHS PF00790.14 CCH58162.1 - 1.1e-46 158.0 0.0 4.1e-46 156.1 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CCH58162.1 - 1.1e-17 64.4 1.8 1.1e-17 64.4 1.2 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.9 CCH58162.1 - 5.2e-15 55.2 6.4 5.9e-15 55.0 1.6 2.9 3 0 0 3 3 3 1 GAT domain TraG-D_C PF12696.2 CCH58162.1 - 0.12 12.2 3.5 3.2 7.6 1.6 3.2 2 1 1 3 3 3 0 TraM recognition site of TraD and TraG Myb_DNA-bind_6 PF13921.1 CCH58163.1 - 3.6e-08 33.3 1.0 3.6e-08 33.3 0.7 4.3 3 1 0 3 3 3 1 Myb-like DNA-binding domain EMP24_GP25L PF01105.19 CCH58164.1 - 5.5e-44 150.0 1.9 6.6e-44 149.8 1.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3753 PF12575.3 CCH58164.1 - 0.073 12.8 1.6 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) ThiF PF00899.16 CCH58165.1 - 8.5e-41 138.9 0.1 1.4e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CCH58165.1 - 5.6e-25 86.7 0.3 9e-25 86.0 0.2 1.3 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CCH58165.1 - 1.1e-14 54.7 0.0 2.2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CCH58165.1 - 0.00043 20.4 0.0 0.0036 17.4 0.0 2.3 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase TPR_MLP1_2 PF07926.7 CCH58165.1 - 0.004 16.9 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF3330 PF11809.3 CCH58165.1 - 0.069 13.0 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) DUF3166 PF11365.3 CCH58165.1 - 0.078 13.4 2.9 0.17 12.3 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) NAD_binding_7 PF13241.1 CCH58165.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Mto2_bdg PF12808.2 CCH58165.1 - 0.22 11.6 4.9 0.14 12.3 1.8 1.8 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region HALZ PF02183.13 CCH58165.1 - 0.38 10.5 7.0 0.4 10.4 3.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cys_Met_Meta_PP PF01053.15 CCH58166.1 - 2.8e-62 210.2 0.0 9e-62 208.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCH58166.1 - 4.8e-07 28.8 0.0 3.1e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCH58166.1 - 0.00064 18.7 0.1 0.0021 17.0 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Alpha-amylase PF00128.19 CCH58166.1 - 0.017 14.4 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, catalytic domain gag_pre-integrs PF13976.1 CCH58166.1 - 0.02 14.5 0.0 0.046 13.3 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Peptidase_M18 PF02127.10 CCH58167.1 - 5.5e-173 575.4 0.1 6.3e-173 575.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CCH58167.1 - 2.1e-08 33.3 0.0 1.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Sugar_tr PF00083.19 CCH58168.1 - 2.8e-153 510.7 32.6 3.2e-153 510.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58168.1 - 2.4e-29 102.1 30.6 5.1e-26 91.2 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58168.1 - 6e-05 21.4 3.1 0.0001 20.6 2.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rad60-SLD PF11976.3 CCH58169.1 - 5.8e-28 96.3 5.1 1.3e-25 88.8 2.3 2.7 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCH58169.1 - 0.0091 15.3 0.3 0.024 14.0 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family Rabaptin PF03528.10 CCH58169.1 - 0.65 9.9 11.1 0.095 12.6 4.5 2.0 2 0 0 2 2 2 0 Rabaptin TUG-UBL1 PF11470.3 CCH58169.1 - 1.6 8.7 5.4 1.7 8.6 0.2 3.3 3 0 0 3 3 3 0 GLUT4 regulating protein TUG RNA_pol_Rpb1_5 PF04998.12 CCH58170.1 - 4.9e-97 324.5 0.1 7.4e-97 323.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CCH58170.1 - 5.7e-84 282.2 0.0 9.1e-84 281.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CCH58170.1 - 1.4e-69 233.3 0.2 2.8e-69 232.3 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCH58170.1 - 7.5e-39 132.9 0.0 2.2e-38 131.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCH58170.1 - 6.8e-32 109.4 0.1 1.9e-31 107.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.8 CCH58171.1 - 6.7e-20 70.6 17.3 9.7e-20 70.1 11.7 1.5 1 1 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.24 CCH58172.1 - 1.1e-40 138.9 0.0 2.4e-40 137.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH58172.1 - 3.4e-05 23.5 1.6 0.00059 19.5 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH58172.1 - 3.6e-05 23.8 0.3 0.011 15.7 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 CCH58172.1 - 3.8e-05 23.6 0.2 0.00018 21.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCH58172.1 - 0.00032 20.8 0.2 0.0077 16.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCH58172.1 - 0.0007 18.7 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCH58172.1 - 0.0033 17.3 0.3 0.017 15.0 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CCH58172.1 - 0.0071 17.1 0.1 0.024 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCH58172.1 - 0.0071 15.5 0.2 0.035 13.3 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 CCH58172.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCH58172.1 - 0.0095 15.6 0.2 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CCH58172.1 - 0.01 15.0 0.1 0.031 13.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 CCH58172.1 - 0.018 14.0 0.0 0.034 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 CCH58172.1 - 0.026 13.9 0.6 0.17 11.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCH58172.1 - 0.035 13.9 0.0 0.099 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCH58172.1 - 0.063 12.3 0.9 0.35 9.9 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 CCH58172.1 - 0.081 12.4 1.8 0.14 11.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCH58172.1 - 0.11 11.5 1.1 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF1192 PF06698.6 CCH58172.1 - 0.26 11.1 2.3 0.71 9.7 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) WD40 PF00400.27 CCH58173.1 - 6.1e-39 130.5 6.3 6.2e-09 35.4 0.0 7.3 6 1 0 6 6 6 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCH58173.1 - 0.04 12.7 0.1 0.42 9.3 0.0 2.5 2 1 0 3 3 3 0 Coatomer WD associated region RIO1 PF01163.17 CCH58174.1 - 3.5e-72 241.7 2.3 3.5e-72 241.7 1.6 2.4 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 CCH58174.1 - 0.017 14.8 0.0 0.29 10.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop14 PF04147.7 CCH58174.1 - 0.02 12.8 26.4 0.031 12.2 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CCH58174.1 - 0.68 9.4 31.7 1.3 8.5 22.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 CCH58174.1 - 1.1 7.2 23.6 1.7 6.5 16.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 CCH58174.1 - 4.7 5.0 16.8 7.3 4.4 11.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Herpes_DNAp_acc PF04929.7 CCH58174.1 - 5.5 5.8 12.3 9 5.1 8.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_M20 PF01546.23 CCH58175.1 - 6.6e-24 84.4 0.0 8.6e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCH58175.1 - 1.4e-09 37.6 0.0 2.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2457 PF10446.4 CCH58176.1 - 0.019 13.7 13.7 0.024 13.3 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP90 PF00183.13 CCH58176.1 - 0.05 11.9 3.5 0.066 11.5 2.4 1.1 1 0 0 1 1 1 0 Hsp90 protein RXT2_N PF08595.6 CCH58176.1 - 0.07 12.9 4.8 0.095 12.4 3.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 CCH58176.1 - 0.24 9.2 4.9 0.27 9.0 3.4 1.1 1 0 0 1 1 1 0 Nop14-like family Herpes_UL32 PF06070.6 CCH58176.1 - 0.26 9.7 2.7 0.33 9.3 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Cwf_Cwc_15 PF04889.7 CCH58176.1 - 0.55 9.9 6.3 0.72 9.5 4.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 CCH58176.1 - 1.1 8.8 7.2 1.4 8.4 5.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Osteopontin PF00865.13 CCH58176.1 - 3 6.9 16.7 4 6.6 11.6 1.1 1 0 0 1 1 1 0 Osteopontin Tom22 PF04281.8 CCH58176.1 - 3 7.3 8.5 4.4 6.8 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CIMR PF00878.13 CCH58177.1 - 0.093 12.4 0.6 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat ABC_membrane PF00664.18 CCH58178.1 - 3.4e-93 312.0 37.3 3.7e-50 170.8 9.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCH58178.1 - 1.1e-46 158.5 1.9 4.1e-28 98.3 1.3 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCH58178.1 - 2.6e-09 36.6 10.4 0.00012 21.3 2.7 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCH58178.1 - 2.3e-08 34.2 0.1 0.011 15.7 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 CCH58178.1 - 4e-06 26.2 0.2 0.057 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCH58178.1 - 1.5e-05 24.9 0.1 0.12 12.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 CCH58178.1 - 2.6e-05 23.6 0.0 0.055 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCH58178.1 - 9.7e-05 22.7 6.6 0.02 15.2 0.1 3.4 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 CCH58178.1 - 0.00017 22.1 1.2 0.31 11.5 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 CCH58178.1 - 0.00023 20.3 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCH58178.1 - 0.002 17.5 0.6 0.6 9.4 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 CCH58178.1 - 0.0033 16.9 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family NTPase_1 PF03266.10 CCH58178.1 - 0.0036 17.0 0.4 2.1 8.0 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_17 PF13207.1 CCH58178.1 - 0.015 16.1 0.2 2.6 8.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCH58178.1 - 0.025 13.5 0.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CCH58178.1 - 0.031 13.3 0.1 5.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 CCH58178.1 - 0.033 14.3 0.2 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 CCH58178.1 - 0.037 13.8 1.3 1.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 CCH58178.1 - 0.044 13.4 1.3 3.3 7.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CCH58178.1 - 0.046 13.4 2.4 0.1 12.3 0.0 2.7 4 0 0 4 4 3 0 Archaeal ATPase DUF87 PF01935.12 CCH58178.1 - 0.078 12.7 6.4 0.78 9.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 cobW PF02492.14 CCH58178.1 - 0.13 11.7 0.8 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CCH58178.1 - 0.14 11.8 0.9 0.75 9.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 CCH58178.1 - 0.24 10.1 0.0 15 4.2 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AIG1 PF04548.11 CCH58178.1 - 0.72 8.9 6.8 0.32 10.0 0.1 2.8 3 0 0 3 3 3 0 AIG1 family Avl9 PF09794.4 CCH58179.1 - 6e-140 466.0 2.0 8.9e-140 465.4 1.4 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CCH58179.1 - 5.8e-07 29.2 0.1 0.0033 17.0 0.0 2.9 3 0 0 3 3 3 2 Stabilization of polarity axis DENN PF02141.16 CCH58179.1 - 0.0066 16.1 1.4 0.082 12.6 0.9 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain DUF1388 PF07142.7 CCH58179.1 - 0.013 15.1 0.2 0.013 15.1 0.1 1.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) efThoc1 PF11957.3 CCH58180.1 - 1.9e-71 241.0 37.4 1.9e-71 241.0 25.9 1.8 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor CPSF100_C PF13299.1 CCH58181.1 - 2.6e-28 99.2 0.3 2.6e-28 99.2 0.2 3.3 2 2 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CCH58181.1 - 9e-12 45.0 0.0 2.3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain zf-CCHC PF00098.18 CCH58182.1 - 2e-07 30.5 11.4 0.00034 20.3 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_3 PF13014.1 CCH58182.1 - 5.4e-06 25.9 0.1 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 CCH58182.1 - 9.1e-06 25.2 0.1 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 CCH58182.1 - 0.011 15.4 6.2 0.34 10.6 1.1 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CCH58182.1 - 0.3 10.8 8.0 0.16 11.6 0.5 2.7 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 CCH58182.1 - 0.42 10.5 5.4 11 5.9 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_4 PF14392.1 CCH58182.1 - 1.3 8.7 6.2 4.8 6.9 0.4 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-HIT PF04438.11 CCH58182.1 - 1.5 8.5 6.8 4.8 6.9 0.4 2.4 1 1 1 2 2 2 0 HIT zinc finger TPR_14 PF13428.1 CCH58183.1 - 3.2e-15 55.2 0.0 0.037 14.6 0.0 7.5 6 2 2 8 8 8 3 Tetratricopeptide repeat HAT PF02184.11 CCH58183.1 - 3.9e-14 52.0 42.6 2.8e-06 26.9 0.1 9.8 11 0 0 11 11 10 5 HAT (Half-A-TPR) repeat Suf PF05843.9 CCH58183.1 - 1.8e-08 34.4 27.0 0.00017 21.3 1.1 5.4 4 1 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CCH58183.1 - 1.6e-07 31.8 0.2 0.17 12.5 0.0 5.4 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCH58183.1 - 1.1e-06 28.8 0.1 0.016 15.5 0.0 4.6 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCH58183.1 - 6.7e-05 22.0 2.8 0.4 9.7 0.6 4.3 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH58183.1 - 0.00013 21.9 2.0 0.81 10.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CCH58183.1 - 0.0036 17.0 2.1 0.0036 17.0 1.4 5.1 4 2 2 6 6 5 2 U3 small nucleolar RNA-associated protein 6 TPR_11 PF13414.1 CCH58183.1 - 0.0037 16.8 9.5 0.16 11.5 0.0 5.0 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.1 CCH58183.1 - 0.0062 16.2 5.7 22 5.1 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCH58183.1 - 0.02 15.3 8.8 35 5.1 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3702 PF12486.3 CCH58183.1 - 0.036 13.7 0.1 0.036 13.7 0.1 2.4 3 0 0 3 3 2 0 ImpA domain protein TPR_7 PF13176.1 CCH58183.1 - 0.083 12.7 7.4 9 6.3 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat HemeBinding_Shp PF11545.3 CCH58183.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp TPR_12 PF13424.1 CCH58183.1 - 0.23 11.4 3.7 56 3.7 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCH58183.1 - 3 7.9 8.3 26 5.0 0.0 5.2 8 0 0 8 8 6 0 Tetratricopeptide repeat Methyltransf_26 PF13659.1 CCH58184.1 - 2.3e-13 50.1 0.0 3e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH58184.1 - 8.3e-09 35.0 0.0 9.6e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CCH58184.1 - 0.00017 20.8 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 CCH58184.1 - 0.077 12.7 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CCH58184.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Dopey_N PF04118.9 CCH58185.1 - 3.5e-116 387.3 3.5 3.5e-116 387.3 2.4 2.5 2 1 1 3 3 3 1 Dopey, N-terminal Abhydrolase_2 PF02230.11 CCH58186.1 - 3e-59 200.0 0.0 3.4e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCH58186.1 - 3.9e-11 42.8 0.0 5.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCH58186.1 - 3.2e-09 36.5 0.1 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CCH58186.1 - 7.3e-07 28.6 0.0 5.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 CCH58186.1 - 9.1e-06 25.7 0.0 0.11 12.3 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCH58186.1 - 0.00015 21.0 0.0 0.0017 17.6 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIP PF03583.9 CCH58186.1 - 0.021 14.0 0.1 0.056 12.6 0.0 1.6 1 1 0 2 2 2 0 Secretory lipase Abhydrolase_3 PF07859.8 CCH58186.1 - 0.028 13.9 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold WD40 PF00400.27 CCH58187.1 - 1.7e-23 81.5 15.4 5.7e-07 29.1 0.1 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-RING_2 PF13639.1 CCH58188.1 - 1.5e-10 40.6 10.0 3.6e-09 36.2 4.1 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CCH58188.1 - 5.3e-08 32.8 2.0 6e-06 26.2 0.9 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCH58188.1 - 1.3e-07 31.2 7.5 1.2e-06 28.0 2.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCH58188.1 - 2.4e-06 27.0 7.1 5.6e-06 25.9 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH58188.1 - 7.2e-06 25.9 10.8 9e-06 25.6 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH58188.1 - 2e-05 24.3 5.6 2e-05 24.3 3.9 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCH58188.1 - 8.7e-05 22.1 10.9 0.00023 20.7 4.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH58188.1 - 0.00022 20.8 2.9 0.00022 20.8 2.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CCH58188.1 - 0.001 18.8 0.3 0.0057 16.4 0.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 CCH58188.1 - 0.025 14.1 1.7 0.067 12.7 1.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CCH58188.1 - 0.066 13.0 0.5 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.16 CCH58188.1 - 0.23 11.3 4.1 0.96 9.3 1.4 2.4 2 0 0 2 2 2 0 IBR domain zf-RING_4 PF14570.1 CCH58188.1 - 0.95 9.1 7.9 0.18 11.3 2.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Asp PF00026.18 CCH58189.1 - 1.8e-68 231.1 5.7 3e-68 230.4 3.9 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH58189.1 - 9.8e-08 32.1 2.3 0.0076 16.2 0.1 3.3 3 1 0 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCH58189.1 - 0.019 15.4 0.3 15 6.1 0.0 3.5 3 0 0 3 3 3 0 Aspartyl protease Cullin PF00888.17 CCH58190.1 - 2.1e-25 89.3 6.7 2.1e-25 89.3 4.6 2.5 2 0 0 2 2 2 2 Cullin family FeoC PF09012.5 CCH58190.1 - 0.002 17.7 0.0 0.011 15.4 0.0 2.2 2 0 0 2 2 2 1 FeoC like transcriptional regulator DUF3804 PF12707.2 CCH58190.1 - 0.0029 17.1 0.1 0.012 15.1 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3804) Cullin_binding PF03556.10 CCH58191.1 - 2e-26 92.3 9.5 3.9e-26 91.4 6.6 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CCH58191.1 - 1.6e-10 40.3 0.2 4.9e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain TFIID_20kDa PF03847.8 CCH58192.1 - 1.3e-26 92.6 0.1 3.3e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A WD40 PF00400.27 CCH58193.1 - 4.5e-71 232.4 32.4 7.1e-09 35.2 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 CCH58193.1 - 2.9e-22 78.6 0.3 5.4e-22 77.7 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCH58193.1 - 2.7e-09 35.7 10.3 3.3e-05 22.2 0.1 5.1 4 1 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCH58193.1 - 9.9e-08 31.1 15.3 0.038 12.7 0.0 6.1 1 1 3 5 5 5 4 Nup133 N terminal like eIF2A PF08662.6 CCH58193.1 - 0.0032 17.2 2.1 0.3 10.7 0.0 4.2 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 CCH58193.1 - 0.094 11.9 4.0 3.1 6.9 0.0 3.5 5 0 0 5 5 5 0 TUP1-like enhancer of split zf-C2H2 PF00096.21 CCH58194.1 - 6.9e-09 35.5 16.3 0.0033 17.6 0.8 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH58194.1 - 1.7e-06 27.9 9.7 0.16 12.3 0.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH58194.1 - 2.3e-05 24.4 9.5 0.0078 16.4 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger double domain HVSL PF09749.4 CCH58195.1 - 4.5e-27 94.6 0.2 7.4e-27 93.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein Guanylin PF02058.10 CCH58195.1 - 0.049 13.6 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Guanylin precursor Choline_kinase PF01633.15 CCH58196.1 - 2.7e-67 226.4 0.1 3.8e-67 225.9 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 CCH58196.1 - 8.7e-12 44.3 0.2 2.3e-11 42.9 0.2 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 CCH58196.1 - 3.7e-10 39.9 0.0 0.00057 19.6 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF3445 PF11927.3 CCH58196.1 - 0.029 13.7 0.2 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Slx4 PF09494.5 CCH58197.1 - 4.3e-14 51.9 0.0 1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Peptidase_M28 PF04389.12 CCH58198.1 - 6e-16 58.6 0.0 1.4e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CCH58198.1 - 5.8e-13 48.5 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCH58198.1 - 3.9e-06 26.4 0.0 8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 CCH58198.1 - 0.016 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Nicastrin DUF4413 PF14372.1 CCH58198.1 - 0.055 13.4 1.2 0.25 11.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Crp PF00325.15 CCH58198.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family RWD PF05773.17 CCH58199.1 - 1.2e-22 79.9 9.8 1.2e-22 79.9 6.8 2.3 1 1 1 2 2 2 1 RWD domain UEV PF05743.8 CCH58199.1 - 0.0096 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 UEV domain ENTH PF01417.15 CCH58200.1 - 1.5e-28 99.1 0.1 2.8e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 ENTH domain Pro_isomerase PF00160.16 CCH58201.1 - 1.2e-47 161.9 0.0 1.3e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_polI_A14 PF08203.6 CCH58202.1 - 1.7e-23 82.6 0.1 1.7e-23 82.6 0.1 1.6 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 MTBP_C PF14920.1 CCH58202.1 - 0.028 13.9 0.2 0.032 13.7 0.2 1.2 1 0 0 1 1 1 0 MDM2-binding Lpp-LpqN PF10738.4 CCH58202.1 - 0.061 12.5 0.1 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Probable lipoprotein LpqN SSP160 PF06933.6 CCH58202.1 - 3.6 5.4 10.3 0.085 10.8 1.2 1.9 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 SAC3_GANP PF03399.11 CCH58203.1 - 6.8e-54 182.5 0.7 6.8e-54 182.5 0.5 2.5 3 0 0 3 3 3 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 CCH58203.1 - 7.9e-13 48.3 1.1 7.9e-13 48.3 0.8 2.2 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Na_H_Exchanger PF00999.16 CCH58204.1 - 2.7e-69 233.5 22.7 3.4e-69 233.2 15.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SLS PF14611.1 CCH58205.1 - 3e-17 62.7 1.5 5.9e-17 61.7 1.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator PAM2 PF07145.10 CCH58206.1 - 0.23 11.0 1.0 15 5.3 0.1 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region ATP_bind_4 PF01902.12 CCH58207.1 - 1.7e-33 115.8 0.0 2.3e-32 112.1 0.0 2.6 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CCH58207.1 - 8.7e-21 73.9 0.0 9.1e-12 44.7 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Glyco_hydro_81 PF03639.8 CCH58209.1 - 1.1e-99 334.4 16.1 1.4e-99 334.0 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Spermine_synth PF01564.12 CCH58210.1 - 5.5e-90 300.5 0.1 7.3e-90 300.1 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 CCH58210.1 - 0.0018 18.0 0.0 0.0047 16.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH58210.1 - 0.0036 17.8 0.0 0.0061 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH58210.1 - 0.0039 17.2 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CCH58210.1 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_12 PF08242.7 CCH58210.1 - 0.014 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CCH58210.1 - 0.048 14.0 0.0 0.086 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.11 CCH58210.1 - 0.05 12.5 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 CCH58210.1 - 0.11 11.6 0.1 0.25 10.5 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase WD40 PF00400.27 CCH58211.1 - 0.00041 20.1 0.3 0.053 13.4 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat LSM PF01423.17 CCH58212.1 - 4.7e-14 51.6 0.4 5.6e-14 51.4 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCH58212.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Pep3_Vps18 PF05131.9 CCH58213.1 - 2e-38 131.0 0.4 8.2e-38 129.1 0.3 2.2 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CCH58213.1 - 2.2e-09 37.0 17.5 4.2e-06 26.4 4.1 3.8 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 CCH58213.1 - 8.6e-05 22.2 2.0 0.00019 21.1 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.4 CCH58213.1 - 0.0017 18.5 2.6 0.0017 18.5 1.8 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 YhdB PF14148.1 CCH58213.1 - 0.0043 16.7 1.2 0.89 9.3 0.1 3.1 2 0 0 2 2 2 1 YhdB-like protein Phage_Coat_A PF05357.8 CCH58213.1 - 0.0092 15.5 0.1 0.026 14.0 0.0 1.8 1 0 0 1 1 1 1 Phage Coat Protein A zf-C3HC4 PF00097.20 CCH58213.1 - 0.023 14.3 2.8 0.067 12.8 1.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH58213.1 - 0.16 11.7 8.2 0.38 10.5 5.7 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCH58213.1 - 0.18 11.8 6.3 0.057 13.4 1.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2415 PF10313.4 CCH58214.1 - 8.3e-22 76.5 0.3 1.7e-21 75.5 0.2 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) MgsA_C PF12002.3 CCH58214.1 - 0.14 11.8 1.3 3.4 7.3 0.2 2.5 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal Stb3 PF10330.4 CCH58215.1 - 2.6e-26 91.1 0.0 5.3e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein Cwf_Cwc_15 PF04889.7 CCH58215.1 - 0.0091 15.7 1.5 0.0091 15.7 1.1 2.1 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Stm1_N PF09598.5 CCH58216.1 - 5e-15 55.9 4.0 5e-15 55.9 2.7 3.7 3 2 1 4 4 4 1 Stm1 Ebola_NP PF05505.7 CCH58216.1 - 0.26 9.3 15.7 0.29 9.1 10.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein NUDIX PF00293.23 CCH58217.1 - 1.1e-15 57.4 0.0 1.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Sec7 PF01369.15 CCH58218.1 - 1.1e-66 224.1 0.0 1.1e-66 224.1 0.0 3.5 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.2 CCH58218.1 - 1.4e-49 167.7 5.3 1.4e-49 167.7 3.6 3.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCH58218.1 - 1.9e-24 84.9 4.2 1.1e-23 82.6 0.3 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) HSP20 PF00011.16 CCH58219.1 - 3.6e-11 42.8 0.0 6.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GTP_EFTU PF00009.22 CCH58220.1 - 2.1e-47 160.9 0.0 6.2e-47 159.4 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCH58220.1 - 1.1e-23 83.2 2.1 1.4e-23 82.8 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCH58220.1 - 1.7e-08 34.4 0.3 5.2e-08 32.8 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH58220.1 - 0.00014 21.7 0.0 0.00062 19.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Med15 PF09606.5 CCH58220.1 - 9.6 4.2 58.7 12 3.9 40.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MFS_1 PF07690.11 CCH58221.1 - 7.3e-32 110.4 34.3 7.3e-32 110.4 23.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58221.1 - 6.3e-05 21.3 1.1 0.00011 20.5 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIR PF00399.14 CCH58222.1 - 4.8e-56 184.3 95.5 1.6e-08 33.5 2.7 8.3 7 1 1 8 8 8 7 Yeast PIR protein repeat LeuA_dimer PF08502.5 CCH58222.1 - 3.2 7.5 17.9 4.7 7.0 0.7 4.1 1 1 3 4 4 4 0 LeuA allosteric (dimerisation) domain Zn_clus PF00172.13 CCH58223.1 - 7.7e-10 38.5 8.7 1.3e-09 37.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 CCH58224.1 - 5.4e-34 116.2 3.7 8.7e-34 115.5 2.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH58224.1 - 5.1e-23 81.0 0.0 8.6e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCH58224.1 - 0.009 16.9 0.0 0.014 16.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 CCH58224.1 - 0.0095 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCH58224.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCH58224.1 - 0.047 14.0 0.1 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CCH58224.1 - 0.079 13.2 0.0 0.5 10.6 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Alb1 PF09135.6 CCH58225.1 - 2.6e-21 76.3 13.8 5.4e-21 75.2 9.6 1.5 1 0 0 1 1 1 1 Alb1 FlgH PF02107.11 CCH58225.1 - 0.037 13.5 0.1 0.074 12.6 0.1 1.5 1 0 0 1 1 1 0 Flagellar L-ring protein Tox-REase-2 PF15646.1 CCH58225.1 - 2.3 8.1 9.1 2.6 7.9 2.2 2.1 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 DUF3073 PF11273.3 CCH58225.1 - 9 6.9 10.0 14 6.3 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) Calreticulin PF00262.13 CCH58226.1 - 5.3e-122 406.9 13.5 7.4e-122 406.5 9.4 1.2 1 0 0 1 1 1 1 Calreticulin family Kelch_4 PF13418.1 CCH58227.1 - 3.8e-11 42.5 9.4 5e-06 26.1 0.1 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CCH58227.1 - 2.2e-06 27.6 1.2 0.0013 18.7 0.0 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CCH58227.1 - 5.3e-06 26.3 9.2 0.0031 17.5 0.0 5.6 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 CCH58227.1 - 6.9e-06 25.8 7.7 1.7 8.7 0.0 6.2 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 CCH58227.1 - 4.1e-05 23.0 7.2 0.087 12.3 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CCH58227.1 - 0.045 13.5 9.0 3.7 7.4 0.1 5.2 6 0 0 6 6 6 0 Kelch motif GDI PF00996.13 CCH58228.1 - 8.6e-57 192.3 0.0 1.1e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Ribosomal_L7Ae PF01248.21 CCH58229.1 - 1.3e-20 72.7 0.5 1.6e-20 72.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 CCH58229.1 - 0.0072 16.3 0.2 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1269) DUF2622 PF11080.3 CCH58229.1 - 0.016 15.0 0.2 0.052 13.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2622) SapB_1 PF05184.10 CCH58229.1 - 0.22 11.4 2.5 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 Rad1 PF02144.11 CCH58230.1 - 1.1e-58 198.2 3.3 1.6e-58 197.6 2.3 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peroxin-22 PF12827.2 CCH58231.1 - 4.2e-16 58.7 3.3 6.7e-16 58.0 2.3 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family CH PF00307.26 CCH58232.1 - 3.1e-10 40.0 0.0 4.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 CCH58232.1 - 0.025 14.6 0.1 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 CDC24 Calponin TRP PF06011.7 CCH58233.1 - 8.9e-157 522.1 37.8 1.1e-156 521.7 26.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCH58233.1 - 5.5e-45 152.8 3.8 9.8e-45 152.0 2.7 1.4 1 0 0 1 1 1 1 ML-like domain DUF4154 PF13689.1 CCH58233.1 - 0.089 12.3 0.0 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4154) Neur_chan_memb PF02932.11 CCH58233.1 - 0.1 12.4 2.4 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DLH PF01738.13 CCH58234.1 - 9e-31 106.8 0.1 1e-30 106.6 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCH58234.1 - 4.6e-07 29.6 0.0 6.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCH58234.1 - 0.062 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Miro PF08477.8 CCH58235.1 - 2.6e-46 156.9 0.0 6e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 CCH58235.1 - 3.7e-27 93.3 0.2 8.1e-27 92.3 0.1 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CCH58235.1 - 4.4e-27 94.4 0.0 1.2e-13 50.8 0.0 2.7 2 1 0 2 2 2 2 Ras family EF_assoc_2 PF08356.7 CCH58235.1 - 3.2e-25 87.7 0.1 1e-24 86.0 0.0 1.9 2 0 0 2 2 2 1 EF hand associated MMR_HSR1 PF01926.18 CCH58235.1 - 9.1e-09 35.2 0.0 0.00092 19.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCH58235.1 - 1.3e-05 24.7 0.0 1.3 8.3 0.0 4.1 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CCH58235.1 - 3.2e-05 23.2 0.0 0.00016 20.9 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family EF-hand_7 PF13499.1 CCH58235.1 - 6.8e-05 22.9 4.8 0.038 14.1 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 CCH58235.1 - 0.0004 20.2 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family EF-hand_1 PF00036.27 CCH58235.1 - 0.00044 19.3 11.1 0.016 14.4 0.7 3.8 3 0 0 3 3 3 2 EF hand AAA_24 PF13479.1 CCH58235.1 - 0.001 18.6 0.0 0.15 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CCH58235.1 - 0.0024 17.9 0.1 4.5 7.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.1 CCH58235.1 - 0.0027 17.7 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 CCH58235.1 - 0.0061 16.0 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CCH58235.1 - 0.013 15.6 0.0 3.7 7.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 CCH58235.1 - 0.013 14.7 0.1 13 5.0 0.0 4.1 5 0 0 5 5 5 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 CCH58235.1 - 0.014 15.1 0.3 4.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase DUF258 PF03193.11 CCH58235.1 - 0.016 14.4 0.1 0.15 11.2 0.0 2.4 3 0 0 3 3 2 0 Protein of unknown function, DUF258 Septin PF00735.13 CCH58235.1 - 0.027 13.5 0.0 0.5 9.3 0.0 2.4 2 0 0 2 2 2 0 Septin EF-hand_6 PF13405.1 CCH58235.1 - 0.028 14.2 8.8 0.18 11.7 0.6 3.1 2 0 0 2 2 2 0 EF-hand domain AAA_29 PF13555.1 CCH58235.1 - 0.03 13.8 0.0 4.1 7.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCH58235.1 - 0.035 14.4 0.0 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 CCH58235.1 - 0.053 13.2 0.5 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCH58235.1 - 0.067 13.4 0.0 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCH58235.1 - 0.073 12.9 0.0 8.5 6.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_32 PF13654.1 CCH58235.1 - 0.093 11.3 0.0 2 6.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain MCM PF00493.18 CCH58235.1 - 0.1 11.4 0.2 14 4.3 0.0 2.7 3 0 0 3 3 3 0 MCM2/3/5 family DUF815 PF05673.8 CCH58235.1 - 0.13 11.1 0.0 4.3 6.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) EF-hand_8 PF13833.1 CCH58235.1 - 0.63 9.7 8.5 1.2 8.7 0.5 2.9 3 0 0 3 3 2 0 EF-hand domain pair EF-hand_5 PF13202.1 CCH58235.1 - 3.4 7.1 12.8 0.12 11.7 1.7 3.1 3 0 0 3 3 3 0 EF hand IncA PF04156.9 CCH58236.1 - 0.0066 16.0 17.4 0.0066 16.0 12.0 4.7 2 1 2 5 5 5 1 IncA protein BolA PF01722.13 CCH58237.1 - 2.2e-16 59.5 0.0 3.9e-16 58.7 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein PDEase_I PF00233.14 CCH58238.1 - 8e-45 153.4 9.7 1e-44 153.1 5.9 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase SAM_2 PF07647.12 CCH58239.1 - 1e-08 34.8 0.0 2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCH58239.1 - 3.8e-05 23.7 0.1 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) COPIIcoated_ERV PF07970.7 CCH58240.1 - 1.6e-73 247.0 0.2 1.9e-73 246.7 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCH58240.1 - 1.4e-27 95.4 0.0 2.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.6 CCH58241.1 - 1.7e-36 124.0 0.8 5e-36 122.6 0.2 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.15 CCH58241.1 - 1.2e-35 122.9 6.0 3.2e-35 121.6 4.1 1.8 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 CCH58241.1 - 3e-21 75.7 3.1 2.5e-20 72.8 2.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 CCH58241.1 - 1.5e-07 30.9 0.8 9.1e-07 28.4 0.1 2.6 3 0 0 3 3 3 1 PB1 domain Cyclin_N PF00134.18 CCH58243.1 - 2.9e-24 85.0 2.8 7.9e-24 83.6 1.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain HEAT PF02985.17 CCH58244.1 - 0.0018 18.1 0.9 4.2 7.7 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat Skp1_POZ PF03931.10 CCH58244.1 - 0.017 15.1 0.3 0.35 11.0 0.0 3.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain PK PF00224.16 CCH58245.1 - 2.1e-164 546.2 2.6 2.9e-164 545.7 1.8 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCH58245.1 - 1.3e-28 98.9 0.0 4.3e-28 97.2 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCH58245.1 - 2.6e-05 23.2 0.5 6e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMS PF00817.15 CCH58246.1 - 1.5e-28 99.4 0.1 3.8e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCH58246.1 - 3.2e-12 46.4 0.0 8.7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 CCH58246.1 - 2.8e-08 33.4 0.1 8.5e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CCH58246.1 - 1.1e-07 31.8 0.1 6.9e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain tRNA-synt_2d PF01409.15 CCH58247.1 - 1.1e-90 303.1 0.0 1.5e-90 302.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCH58247.1 - 3.7e-07 29.8 0.0 6.2e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CCH58247.1 - 1.4e-06 27.3 0.2 5.1e-05 22.1 0.0 3.1 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.1 CCH58247.1 - 0.014 14.4 0.0 0.091 11.8 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF2084 PF09857.4 CCH58247.1 - 0.083 12.5 0.2 0.46 10.2 0.0 2.3 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2084) SHS2_Rpb7-N PF03876.12 CCH58249.1 - 1.3e-10 41.2 0.0 2.5e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SWIRM PF04433.12 CCH58250.1 - 1.2e-14 54.1 0.0 2.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NT-C2 PF10358.4 CCH58250.1 - 0.017 14.6 0.0 0.062 12.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins UDP-g_GGTase PF06427.6 CCH58251.1 - 4e-10 39.3 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase tRNA-synt_2c PF01411.14 CCH58252.1 - 7.2e-221 734.2 0.1 6.9e-220 731.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CCH58252.1 - 2e-18 66.0 0.1 5.3e-18 64.6 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CCH58252.1 - 3.9e-07 29.6 1.0 9.3e-07 28.4 0.7 1.7 1 0 0 1 1 1 1 DHHA1 domain Synaptobrevin PF00957.16 CCH58254.1 - 1.6e-32 110.9 1.0 1.9e-32 110.7 0.7 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 CCH58254.1 - 0.17 11.9 1.6 0.18 11.8 1.1 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hph PF13694.1 CCH58255.1 - 5.4e-12 46.1 15.6 5.4e-12 46.1 10.8 3.2 2 1 1 3 3 3 1 Sec63/Sec62 complex-interacting family Prefoldin_2 PF01920.15 CCH58255.1 - 2.8 7.7 12.6 0.12 12.1 4.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit HAD PF12710.2 CCH58256.1 - 1e-19 71.4 0.1 3.7e-19 69.6 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCH58256.1 - 1.1e-16 60.6 0.3 1.8e-16 59.8 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCH58256.1 - 5.2e-13 49.9 0.5 1.1e-11 45.5 0.3 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH58256.1 - 6.2e-09 35.6 0.0 1.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCH58256.1 - 0.0021 17.6 2.0 0.013 15.1 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCH58256.1 - 0.086 13.0 0.1 0.33 11.1 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LDB19 PF13002.2 CCH58257.1 - 1.3e-72 243.3 1.5 2.8e-72 242.2 1.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like PMT PF02366.13 CCH58258.1 - 8.4e-89 297.1 22.3 8.4e-89 297.1 15.5 2.2 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCH58258.1 - 4.8e-34 117.5 1.6 8.2e-34 116.8 1.1 1.4 1 0 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.13 CCH58259.1 - 3.7e-53 180.6 24.4 4.1e-39 134.5 7.3 3.0 1 1 2 3 3 3 2 Nucleoside transporter Exo_endo_phos PF03372.18 CCH58260.1 - 1.9e-23 83.6 0.1 3e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CCH58260.1 - 3.5e-14 52.0 13.8 2.4e-08 33.3 2.9 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH58260.1 - 1.1e-09 37.8 7.5 1.1e-09 37.8 0.9 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CCH58260.1 - 1.1e-07 30.8 12.6 0.0046 16.7 0.1 4.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CCH58260.1 - 1e-05 24.9 7.5 0.011 15.8 0.2 4.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CCH58260.1 - 0.45 10.7 0.1 0.45 10.7 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat Plasmodium_Vir PF05795.6 CCH58260.1 - 7.4 5.6 18.6 4.2 6.4 5.0 2.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RCC1 PF00415.13 CCH58261.1 - 1.6e-19 69.8 10.0 4e-06 26.9 0.0 7.3 6 2 1 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCH58261.1 - 1.2e-12 47.0 17.7 2.2e-06 27.1 0.1 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.18 CCH58262.1 - 3.8e-69 232.7 0.5 5.9e-69 232.1 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH58262.1 - 2.9e-16 59.0 0.1 1.2e-14 53.8 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HHH_3 PF12836.2 CCH58262.1 - 0.0014 18.5 0.6 0.0056 16.5 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif GSH_synth_ATP PF03917.12 CCH58263.1 - 7.2e-121 403.2 0.0 8.7e-121 402.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CCH58263.1 - 4.1e-36 123.2 0.2 7.9e-36 122.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3139 PF11337.3 CCH58264.1 - 0.061 13.5 1.0 0.061 13.5 0.7 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3139) Pkinase PF00069.20 CCH58265.1 - 4.6e-60 202.9 0.1 8.8e-60 202.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58265.1 - 3.8e-22 78.6 0.0 6.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58265.1 - 7e-10 38.3 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 CCH58265.1 - 1.6e-05 25.1 0.0 0.0014 18.9 0.0 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.19 CCH58265.1 - 0.0057 16.4 0.0 3.2 7.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold APH PF01636.18 CCH58265.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCH58265.1 - 0.067 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNAPc19 PF15497.1 CCH58265.1 - 2.8 8.2 11.5 0.065 13.4 0.3 2.9 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Oxidored_FMN PF00724.15 CCH58266.1 - 2.8e-62 210.6 0.0 3.4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HhH-GPD PF00730.20 CCH58267.1 - 1.6e-22 79.7 0.0 3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCH58267.1 - 1.5e-05 24.4 0.0 3.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 CCH58268.1 - 1.8e-18 65.9 3.4 5.4e-14 51.5 0.1 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58268.1 - 3.3e-16 59.0 1.7 1.4e-11 44.2 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58268.1 - 1.7e-11 43.7 3.0 4.4e-06 26.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 CCH58268.1 - 0.024 14.0 0.0 0.43 10.0 0.0 3.0 2 0 0 2 2 2 0 Sporulation protein family 7 Ribosomal_S19 PF00203.16 CCH58269.1 - 2.3e-32 110.4 0.1 3.5e-32 109.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3619 PF12279.3 CCH58269.1 - 0.099 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Ribosomal_60s PF00428.14 CCH58270.1 - 2.2e-25 88.8 16.5 2.6e-25 88.6 11.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Fer4_NifH PF00142.13 CCH58270.1 - 0.12 11.5 0.0 0.13 11.4 0.0 1.0 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF3138 PF11336.3 CCH58270.1 - 0.37 8.8 5.1 0.38 8.8 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Acetyltransf_7 PF13508.1 CCH58272.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain B56 PF01603.15 CCH58273.1 - 3.7e-146 486.9 18.9 4.2e-138 460.3 9.4 2.3 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) EMP24_GP25L PF01105.19 CCH58274.1 - 1.5e-29 102.9 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NERD PF08378.6 CCH58274.1 - 0.025 14.8 0.1 0.035 14.3 0.1 1.4 1 1 0 1 1 1 0 Nuclease-related domain TP6A_N PF04406.9 CCH58275.1 - 3.1e-09 36.3 0.9 7.2e-09 35.1 0.6 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Toprim PF01751.17 CCH58275.1 - 0.05 13.5 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Toprim domain PQ-loop PF04193.9 CCH58276.1 - 1.8e-11 43.4 15.8 8.4e-11 41.2 1.4 3.7 3 1 1 4 4 4 2 PQ loop repeat ARD PF03079.9 CCH58277.1 - 7.3e-45 152.7 1.4 9e-45 152.4 1.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CCH58277.1 - 9.3e-11 41.0 0.0 1.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CCH58277.1 - 2.2e-05 24.1 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CCH58277.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 CCH58277.1 - 0.015 14.8 0.1 0.037 13.5 0.0 1.5 1 1 1 2 2 2 0 Cupin-like domain Nuc_rec_co-act PF08815.5 CCH58277.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Nuclear receptor coactivator JmjC PF02373.17 CCH58277.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 JmjC domain, hydroxylase Glyco_hydro_72 PF03198.9 CCH58278.1 - 1.4e-142 474.3 7.0 1.8e-142 473.9 4.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 CCH58278.1 - 0.00084 18.6 0.2 0.0065 15.7 0.1 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Nop14 PF04147.7 CCH58278.1 - 0.89 7.3 12.8 1.2 7.0 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF572 PF04502.8 CCH58278.1 - 8.4 5.5 19.4 13 4.9 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) bZIP_1 PF00170.16 CCH58279.1 - 8.1e-05 22.4 12.3 8.1e-05 22.4 8.5 2.7 2 1 0 2 2 2 1 bZIP transcription factor LETM1 PF07766.8 CCH58280.1 - 2e-90 302.4 5.6 3.9e-90 301.5 3.9 1.4 1 0 0 1 1 1 1 LETM1-like protein TOM13 PF08219.6 CCH58281.1 - 1.3e-18 66.5 0.0 1.7e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Sugar_tr PF00083.19 CCH58284.1 - 1e-164 548.4 36.7 1.2e-164 548.1 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58284.1 - 3.8e-31 108.0 23.2 3.8e-31 108.0 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCH58284.1 - 0.00032 19.2 32.2 0.0041 15.5 9.9 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 CCH58284.1 - 0.00044 18.4 5.5 0.00062 18.0 1.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector ATP1G1_PLM_MAT8 PF02038.11 CCH58284.1 - 0.013 14.4 2.5 0.72 8.9 0.8 3.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PDR_CDR PF06422.7 CCH58284.1 - 3.5 7.3 0.0 3.5 7.3 0.0 3.4 3 0 0 3 3 3 0 CDR ABC transporter PALP PF00291.20 CCH58285.1 - 7.2e-60 202.7 0.0 8.2e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KH_1 PF00013.24 CCH58287.1 - 0.0027 17.2 0.0 0.0062 16.1 0.0 1.6 1 0 0 1 1 1 1 KH domain Pfg27 PF09216.5 CCH58287.1 - 0.036 13.6 0.2 0.036 13.6 0.1 1.8 2 0 0 2 2 2 0 Pfg27 KH_3 PF13014.1 CCH58287.1 - 0.044 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 KH domain Siah-Interact_N PF09032.6 CCH58287.1 - 7.5 6.6 14.4 0.82 9.7 4.0 2.7 2 1 1 3 3 3 0 Siah interacting protein, N terminal LPP PF04728.8 CCH58288.1 - 0.066 13.0 2.7 0.11 12.3 1.9 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF543 PF04418.7 CCH58289.1 - 9.6e-30 102.3 0.2 1.1e-29 102.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) PEX11 PF05648.9 CCH58290.1 - 3.3e-06 26.5 1.3 4.4e-06 26.1 0.9 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Med9 PF07544.8 CCH58291.1 - 0.033 13.9 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MT-A70 PF05063.9 CCH58292.1 - 9.2e-13 48.1 0.6 4.1e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 MT-A70 ATP_transf PF09830.4 CCH58294.1 - 9.9e-19 66.9 0.0 2.1e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CCH58294.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.6 1 0 0 1 1 1 1 HIT domain Pmp3 PF01679.12 CCH58295.1 - 2e-21 75.4 4.7 2.4e-21 75.1 3.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator COX15-CtaA PF02628.10 CCH58295.1 - 0.044 12.6 0.2 0.053 12.3 0.1 1.0 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein ABC2_membrane_4 PF12730.2 CCH58295.1 - 0.047 12.8 0.6 0.051 12.7 0.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein ETRAMP PF09716.5 CCH58296.1 - 0.13 12.2 0.6 0.17 11.8 0.4 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) QCR10 PF09796.4 CCH58296.1 - 0.37 10.4 2.9 0.76 9.4 2.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Thioredoxin PF00085.15 CCH58297.1 - 1.3e-58 195.0 1.3 2.2e-29 101.2 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CCH58297.1 - 8.1e-28 97.4 11.1 8.6e-18 64.7 5.0 4.1 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CCH58297.1 - 2.7e-10 40.4 4.7 0.0019 18.4 0.1 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCH58297.1 - 3.1e-09 36.8 0.7 0.027 14.5 0.1 4.9 4 1 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CCH58297.1 - 1.9e-08 34.1 0.2 0.014 15.4 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 CCH58297.1 - 6.2e-05 22.6 0.2 0.077 12.6 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 CCH58297.1 - 0.00054 19.5 0.1 0.53 9.8 0.0 2.7 2 0 0 2 2 2 2 Redoxin TraF PF13728.1 CCH58297.1 - 0.041 13.3 0.0 5 6.5 0.0 2.6 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CCH58297.1 - 0.08 12.5 9.8 1.6 8.3 0.0 4.1 5 0 0 5 5 5 0 Thioredoxin Thioredoxin_4 PF13462.1 CCH58297.1 - 0.08 12.9 8.0 8 6.4 1.8 4.2 3 2 1 4 4 4 0 Thioredoxin DSBA PF01323.15 CCH58297.1 - 0.092 12.2 0.7 3.3 7.2 0.0 3.4 2 2 1 3 3 3 0 DSBA-like thioredoxin domain Hexokinase_2 PF03727.11 CCH58298.1 - 2.3e-86 288.9 0.0 3.5e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCH58298.1 - 1e-72 243.7 0.1 5.8e-72 241.3 0.1 1.9 2 0 0 2 2 2 1 Hexokinase ATG22 PF11700.3 CCH58299.1 - 1e-158 528.7 30.6 1.2e-158 528.5 21.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like La PF05383.12 CCH58300.1 - 2.5e-19 68.7 0.1 7.9e-19 67.2 0.0 1.9 2 0 0 2 2 2 1 La domain Macoilin PF09726.4 CCH58300.1 - 0.73 8.0 38.9 1.2 7.3 26.9 1.4 1 0 0 1 1 1 0 Transmembrane protein Ebola_NP PF05505.7 CCH58300.1 - 1.5 6.8 26.9 2.1 6.2 18.7 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein Glutaredoxin PF00462.19 CCH58301.1 - 6.1e-11 42.1 0.0 9.7e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GAT PF03127.9 CCH58302.1 - 0.00063 19.6 2.3 0.0012 18.8 0.0 2.5 2 1 1 3 3 3 1 GAT domain RRP7 PF12923.2 CCH58303.1 - 1e-31 109.6 7.7 1e-31 109.6 5.3 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Complex1_LYR PF05347.10 CCH58304.1 - 2.5e-09 36.7 0.1 2.5e-09 36.7 0.1 2.2 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCH58304.1 - 1.2e-08 35.0 0.2 5.9e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCH58304.1 - 1e-06 29.1 0.3 1.8e-06 28.3 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like CSTF2_hinge PF14327.1 CCH58304.1 - 0.1 12.6 0.8 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 SH3_2 PF07653.12 CCH58305.1 - 0.00063 19.1 0.5 0.004 16.6 0.4 2.4 1 1 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.1 CCH58305.1 - 0.0014 18.1 0.3 0.0045 16.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) SH3_9 PF14604.1 CCH58305.1 - 0.0076 15.8 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain DUF4013 PF13197.1 CCH58305.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) SH3_1 PF00018.23 CCH58305.1 - 0.049 13.0 0.0 0.23 10.8 0.0 2.1 1 1 1 2 2 2 0 SH3 domain DUF912 PF06024.7 CCH58305.1 - 0.061 13.3 1.4 0.47 10.5 0.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SKG6 PF08693.5 CCH58305.1 - 0.089 12.1 0.1 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Nitroreductase PF00881.19 CCH58306.1 - 0.0034 17.2 0.0 0.0062 16.3 0.0 1.5 1 1 0 1 1 1 1 Nitroreductase family Tir_receptor_N PF07490.6 CCH58307.1 - 0.52 9.8 3.6 0.9 9.1 2.5 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus IL6 PF00489.12 CCH58307.1 - 3.2 7.3 9.1 2.6 7.5 0.7 3.1 2 1 1 3 3 3 0 Interleukin-6/G-CSF/MGF family Nitroreductase PF00881.19 CCH58308.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family DUF512 PF04459.7 CCH58308.1 - 0.02 13.9 0.0 0.045 12.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Nitroreductase PF00881.19 CCH58309.1 - 1.2e-05 25.1 0.1 2.4e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.19 CCH58310.1 - 2.9e-10 40.2 0.0 3.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family AA_permease PF00324.16 CCH58311.1 - 5.4e-121 404.2 34.8 6.6e-121 403.9 24.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH58311.1 - 1.5e-31 109.3 35.5 1.9e-31 109.0 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.8 CCH58311.1 - 0.2 11.4 3.3 0.15 11.8 0.5 2.0 2 0 0 2 2 2 0 Colicin immunity protein DUF1625 PF07787.7 CCH58311.1 - 0.34 10.1 2.0 0.82 8.8 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) AA_permease PF00324.16 CCH58312.1 - 1.7e-121 405.9 32.7 1.9e-121 405.7 22.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH58312.1 - 5.6e-32 110.8 34.7 7e-32 110.4 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.8 CCH58312.1 - 1.5 8.6 7.1 0.13 11.9 0.7 2.3 3 0 0 3 3 3 0 Colicin immunity protein Na_trans_assoc PF06512.8 CCH58312.1 - 5.8 6.8 9.5 9 6.1 6.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated OapA_N PF08525.6 CCH58312.1 - 6.7 6.6 7.3 0.31 10.8 0.2 2.6 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif PSP1 PF04468.7 CCH58313.1 - 1.5e-33 114.5 0.7 1.5e-33 114.5 0.5 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region U1snRNP70_N PF12220.3 CCH58313.1 - 0.0034 17.6 1.2 0.18 12.1 0.3 2.8 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4175 PF13779.1 CCH58313.1 - 6.5 4.3 15.5 9.8 3.7 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PBP PF01161.15 CCH58314.1 - 2e-28 99.0 0.2 2.6e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PAP2 PF01569.16 CCH58315.1 - 1.8e-20 72.9 0.6 1.8e-20 72.9 0.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily FUSC_2 PF13515.1 CCH58315.1 - 0.00091 19.1 0.2 0.00091 19.1 0.1 2.2 3 0 0 3 3 3 1 Fusaric acid resistance protein-like PAP2_C PF14360.1 CCH58315.1 - 0.0011 19.1 1.8 0.0011 19.1 1.2 2.9 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF605 PF04652.11 CCH58316.1 - 5.5e-51 174.1 7.2 6.9e-51 173.8 5.0 1.1 1 0 0 1 1 1 1 Vta1 like Cas_Csa5 PF09702.5 CCH58316.1 - 0.078 13.0 0.9 0.19 11.7 0.6 1.6 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) FHA PF00498.21 CCH58317.1 - 1.2e-05 25.3 0.0 4.1e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 FHA domain DUF2203 PF09969.4 CCH58317.1 - 0.011 15.9 1.1 0.031 14.5 0.2 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosomal_L37e PF01907.14 CCH58318.1 - 5.4e-28 96.5 12.2 5.4e-28 96.5 8.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CCH58318.1 - 0.00055 19.6 2.0 0.00083 19.1 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CCH58318.1 - 0.023 14.3 0.4 0.03 14.0 0.3 1.3 1 1 0 1 1 1 0 SelR domain zinc_ribbon_6 PF14599.1 CCH58318.1 - 0.077 12.8 2.1 0.12 12.2 1.4 1.2 1 0 0 1 1 1 0 Zinc-ribbon DUF1258 PF06869.7 CCH58318.1 - 0.15 11.1 0.5 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-RING_5 PF14634.1 CCH58318.1 - 0.17 11.6 3.2 0.26 11.0 2.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-ribbon_3 PF13248.1 CCH58318.1 - 0.19 10.9 3.7 0.47 9.7 2.6 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 CCH58318.1 - 0.2 11.3 2.6 0.27 10.9 1.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GATA PF00320.22 CCH58318.1 - 0.43 9.9 6.3 0.48 9.8 0.9 2.3 1 1 1 2 2 2 0 GATA zinc finger zf-C3HC4_2 PF13923.1 CCH58318.1 - 0.92 9.5 4.8 1.4 9.0 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH58318.1 - 0.98 9.1 4.9 1.6 8.4 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.4 CCH58318.1 - 2.4 7.9 6.4 1.5 8.6 0.7 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_2 PF13240.1 CCH58318.1 - 3.8 7.1 5.7 38 3.9 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain LCD1 PF09798.4 CCH58319.1 - 1.4e-119 400.0 56.4 8e-65 219.0 14.1 2.3 1 1 1 2 2 2 2 DNA damage checkpoint protein EMG1 PF03587.9 CCH58320.1 - 8.5e-76 253.7 0.0 1e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TMEM220 PF15071.1 CCH58321.1 - 0.0057 17.0 0.2 0.045 14.1 0.0 2.6 2 0 0 2 2 2 1 Transmembrane family 220, helix Tetraspannin PF00335.15 CCH58321.1 - 0.042 13.1 6.6 2.3 7.4 0.1 3.3 3 0 0 3 3 3 0 Tetraspanin family PH PF00169.24 CCH58322.1 - 3e-05 24.1 6.7 8.4e-05 22.7 0.5 3.1 2 1 0 2 2 2 2 PH domain ABC_membrane PF00664.18 CCH58323.1 - 1.6e-51 175.3 3.9 2e-51 175.0 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCH58323.1 - 1.8e-33 115.7 0.0 5.2e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCH58323.1 - 8.2e-09 35.0 0.0 1.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCH58323.1 - 3.2e-05 24.7 0.0 9.2e-05 23.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCH58323.1 - 8.7e-05 22.5 0.0 0.00027 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CCH58323.1 - 0.00017 21.8 0.1 0.02 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCH58323.1 - 0.00058 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH58323.1 - 0.00076 19.5 10.1 0.0025 17.8 0.2 3.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCH58323.1 - 0.0043 17.2 0.1 0.039 14.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCH58323.1 - 0.014 15.1 0.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CCH58323.1 - 0.015 15.1 0.9 0.042 13.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 DUF258 PF03193.11 CCH58323.1 - 0.019 14.1 0.1 0.086 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCH58323.1 - 0.026 13.9 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 CCH58323.1 - 0.029 14.3 0.1 0.12 12.2 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF4116 PF13475.1 CCH58323.1 - 0.033 13.6 0.2 6 6.4 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) AAA_23 PF13476.1 CCH58323.1 - 0.035 14.4 0.1 0.035 14.4 0.1 3.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCH58323.1 - 0.11 11.8 0.0 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCH58323.1 - 0.13 12.1 0.1 0.67 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Abhydrolase_1 PF00561.15 CCH58324.1 - 1e-54 185.5 0.0 1.7e-54 184.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCH58324.1 - 4.3e-11 43.1 0.1 9.2e-10 38.7 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH58324.1 - 0.00062 19.5 0.0 0.016 14.9 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_transf_28 PF03033.15 CCH58325.1 - 4.8e-28 97.6 0.0 9.3e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CCH58325.1 - 1.9e-22 78.5 1.6 4.5e-12 45.3 0.0 3.2 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 CCH58325.1 - 1.9e-08 34.4 1.5 1.9e-08 34.4 1.1 2.6 2 0 0 2 2 2 1 PH domain UDPGT PF00201.13 CCH58325.1 - 6.9e-08 31.4 0.0 1.8e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 CCH58325.1 - 0.016 14.4 0.0 0.05 12.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 1 PH_11 PF15413.1 CCH58325.1 - 0.075 13.2 9.6 0.076 13.2 1.3 4.1 2 1 0 2 2 2 0 Pleckstrin homology domain Exo_endo_phos PF03372.18 CCH58326.1 - 4e-20 72.8 0.1 5.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MARVEL PF01284.18 CCH58326.1 - 0.018 14.8 0.3 0.03 14.1 0.2 1.3 1 0 0 1 1 1 0 Membrane-associating domain EamA PF00892.15 CCH58326.1 - 0.27 11.2 5.8 0.24 11.4 2.3 2.0 2 0 0 2 2 2 0 EamA-like transporter family Spindle_Spc25 PF08234.7 CCH58327.1 - 4.2e-11 42.6 0.6 4.2e-11 42.6 0.4 3.2 3 1 1 4 4 3 1 Chromosome segregation protein Spc25 IncA PF04156.9 CCH58327.1 - 0.00011 21.8 12.7 0.00021 20.9 8.8 1.5 1 1 0 1 1 1 1 IncA protein Rab5-bind PF09311.6 CCH58327.1 - 0.0019 18.1 4.1 0.0029 17.5 2.8 1.4 1 0 0 1 1 1 1 Rabaptin-like protein Myosin_tail_1 PF01576.14 CCH58327.1 - 0.002 15.9 10.9 0.0027 15.5 7.6 1.2 1 0 0 1 1 1 1 Myosin tail DivIC PF04977.10 CCH58327.1 - 0.0032 16.9 5.0 0.0032 16.9 3.5 2.9 2 1 1 3 3 3 1 Septum formation initiator CALCOCO1 PF07888.6 CCH58327.1 - 0.0033 15.8 11.5 0.01 14.1 7.9 1.7 1 1 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CHASE3 PF05227.8 CCH58327.1 - 0.0038 16.8 3.4 0.0056 16.3 2.4 1.3 1 0 0 1 1 1 1 CHASE3 domain ADIP PF11559.3 CCH58327.1 - 0.017 15.0 14.1 0.017 15.0 9.7 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ax_dynein_light PF10211.4 CCH58327.1 - 0.017 14.9 11.5 0.038 13.8 8.0 1.6 1 0 0 1 1 1 0 Axonemal dynein light chain PspA_IM30 PF04012.7 CCH58327.1 - 0.027 13.8 4.3 0.037 13.3 2.5 1.5 1 1 1 2 2 2 0 PspA/IM30 family Reo_sigmaC PF04582.7 CCH58327.1 - 0.03 13.5 1.1 0.038 13.1 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Mitofilin PF09731.4 CCH58327.1 - 0.037 12.7 13.5 0.054 12.1 9.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Spc7 PF08317.6 CCH58327.1 - 0.085 11.5 19.1 0.16 10.5 12.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 CCH58327.1 - 0.12 12.2 14.1 0.2 11.4 9.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) IFT57 PF10498.4 CCH58327.1 - 0.13 11.0 20.2 0.029 13.0 11.5 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 TPR_MLP1_2 PF07926.7 CCH58327.1 - 0.13 12.0 13.4 0.058 13.1 7.1 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4472 PF14739.1 CCH58327.1 - 0.21 12.0 9.6 0.17 12.3 5.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) APG6 PF04111.7 CCH58327.1 - 0.24 10.4 17.2 0.39 9.7 11.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HOOK PF05622.7 CCH58327.1 - 0.31 8.7 16.7 0.53 8.0 7.5 1.7 1 1 1 2 2 2 0 HOOK protein NAD_binding_6 PF08030.7 CCH58327.1 - 0.36 10.7 7.5 1 9.2 2.6 2.3 2 0 0 2 2 2 0 Ferric reductase NAD binding domain CENP-F_leu_zip PF10473.4 CCH58327.1 - 0.38 10.6 12.5 1.6 8.5 7.6 2.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.1 CCH58327.1 - 0.45 10.6 5.6 9.1 6.4 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) YlqD PF11068.3 CCH58327.1 - 0.5 10.3 11.9 0.43 10.6 7.2 1.7 1 1 0 1 1 1 0 YlqD protein SlyX PF04102.7 CCH58327.1 - 0.51 10.7 8.2 0.54 10.6 3.1 2.5 1 1 1 2 2 2 0 SlyX DUF972 PF06156.8 CCH58327.1 - 0.52 10.6 15.8 1.2 9.4 6.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Viral_P18 PF04521.8 CCH58327.1 - 0.62 9.5 3.9 0.86 9.0 1.9 1.8 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TMF_TATA_bd PF12325.3 CCH58327.1 - 0.66 9.7 10.1 1 9.0 6.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding EAP30 PF04157.11 CCH58327.1 - 0.76 8.8 9.7 7.7 5.5 0.2 2.2 1 1 1 2 2 2 0 EAP30/Vps36 family Atg14 PF10186.4 CCH58327.1 - 0.92 8.3 11.6 1.6 7.6 8.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_I PF06008.9 CCH58327.1 - 1.1 8.4 22.2 6.6 5.9 15.4 2.3 1 1 0 1 1 1 0 Laminin Domain I TMF_DNA_bd PF12329.3 CCH58327.1 - 1.5 8.7 18.7 8.9 6.1 11.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 CCH58327.1 - 1.6 8.1 21.8 0.73 9.2 13.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Pox_A_type_inc PF04508.7 CCH58327.1 - 1.6 8.6 7.1 8.1 6.5 0.0 4.0 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 CCH58327.1 - 1.6 8.6 11.6 1.8 8.4 1.8 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.5 CCH58327.1 - 1.9 8.5 13.1 1.8 8.6 7.5 2.0 1 1 1 2 2 2 0 Cortexillin I, coiled coil Syntaxin-6_N PF09177.6 CCH58327.1 - 2.6 8.5 12.2 1.4 9.3 5.1 2.6 2 1 1 3 3 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 CCH58327.1 - 3 7.8 11.4 8.6 6.4 1.1 2.6 1 1 1 2 2 2 0 bZIP transcription factor DivIVA PF05103.8 CCH58327.1 - 3.7 7.6 16.3 3.6 7.6 1.6 2.5 2 1 1 3 3 2 0 DivIVA protein HsbA PF12296.3 CCH58327.1 - 4.3 7.2 10.4 1.2 8.9 4.8 2.0 3 0 0 3 3 1 0 Hydrophobic surface binding protein A GrpE PF01025.14 CCH58327.1 - 7.8 6.0 13.1 6.3 6.3 6.3 2.6 2 1 0 2 2 1 0 GrpE Per1 PF04080.8 CCH58328.1 - 1.9e-95 319.3 12.6 2.4e-95 318.9 8.8 1.1 1 0 0 1 1 1 1 Per1-like Adeno_terminal PF02459.10 CCH58328.1 - 0.045 11.9 0.1 0.065 11.3 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Tetraspannin PF00335.15 CCH58328.1 - 0.36 10.0 5.3 0.66 9.2 3.7 1.5 1 0 0 1 1 1 0 Tetraspanin family HCO3_cotransp PF00955.16 CCH58329.1 - 7.5e-56 189.8 16.7 4.9e-36 124.4 3.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family 2-Hacid_dh_C PF02826.14 CCH58331.1 - 1e-54 184.3 0.0 2e-54 183.4 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCH58331.1 - 2.2e-15 56.3 0.0 3.7e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCH58331.1 - 1.6e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCH58331.1 - 1.8e-06 27.3 0.0 3.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 CCH58331.1 - 0.00012 22.1 0.1 0.00072 19.6 0.0 2.1 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCH58331.1 - 0.0076 16.6 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 CCH58331.1 - 0.011 15.5 0.1 0.056 13.2 0.0 2.2 3 0 0 3 3 3 0 ThiF family TrkA_N PF02254.13 CCH58331.1 - 0.021 14.8 0.0 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.16 CCH58331.1 - 0.047 13.5 0.0 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NADPH_Ox PF08414.5 CCH58331.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase GFO_IDH_MocA PF01408.17 CCH58331.1 - 0.13 12.8 0.1 0.31 11.5 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sad1_UNC PF07738.8 CCH58333.1 - 5e-32 110.5 0.1 1.3e-31 109.1 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_S8 PF00082.17 CCH58334.1 - 1e-13 51.0 0.0 1.5e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Subtilase family TIMELESS PF04821.9 CCH58335.1 - 8.4e-45 153.0 11.8 8.4e-45 153.0 8.2 2.8 2 1 0 2 2 2 1 Timeless protein Sec2p PF06428.6 CCH58336.1 - 4.3e-26 90.7 16.5 4.3e-26 90.7 11.4 3.3 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p ArfGap PF01412.13 CCH58336.1 - 0.0035 17.1 2.4 0.01 15.6 0.0 2.9 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf FH2 PF02181.18 CCH58337.1 - 4.6e-84 282.4 12.2 4.6e-84 282.4 8.5 4.4 3 1 1 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CCH58337.1 - 1.8e-40 138.4 4.8 1.8e-40 138.4 3.3 5.2 6 0 0 6 6 6 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 CCH58337.1 - 1.6e-25 89.5 10.2 2.4e-21 75.9 1.3 6.2 7 1 0 7 7 7 2 Diaphanous GTPase-binding Domain AA_permease PF00324.16 CCH58338.1 - 5e-132 440.6 46.4 6.1e-132 440.3 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH58338.1 - 1.7e-30 105.9 50.8 2.4e-30 105.4 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCH58339.1 - 2.2e-130 435.2 49.1 2.8e-130 434.8 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH58339.1 - 2.1e-32 112.2 51.3 2.6e-32 111.9 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease PI3_PI4_kinase PF00454.22 CCH58340.1 - 1.1e-29 103.5 0.0 1.1e-29 103.5 0.0 2.3 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CCH58340.1 - 1.2e-16 60.1 0.2 4.2e-16 58.4 0.1 2.1 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CCH58340.1 - 3.4e-06 26.3 2.7 8.1e-06 25.1 1.9 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Mmp37 PF09139.6 CCH58341.1 - 5.7e-96 321.4 12.2 2e-87 293.3 3.6 2.0 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 Ist1 PF03398.9 CCH58342.1 - 1e-41 142.1 1.8 3.8e-41 140.2 1.3 1.8 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TPR_11 PF13414.1 CCH58343.1 - 3.6e-15 55.3 21.7 5e-07 29.2 0.2 7.1 8 0 0 8 8 8 3 TPR repeat TPR_8 PF13181.1 CCH58343.1 - 1.6e-14 52.4 12.6 5.7e-05 22.6 0.0 7.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCH58343.1 - 2e-14 52.2 15.8 0.00042 20.0 0.0 9.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCH58343.1 - 2.3e-12 45.9 12.8 0.00017 21.0 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCH58343.1 - 5.1e-11 42.1 0.1 7.1 7.5 0.0 7.4 6 1 2 8 8 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH58343.1 - 2.9e-10 40.5 4.4 0.15 12.7 0.1 6.9 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCH58343.1 - 3e-10 39.8 16.8 0.0002 21.2 0.1 6.2 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCH58343.1 - 5e-10 39.1 2.3 0.24 11.9 0.0 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH58343.1 - 3.5e-08 33.0 12.6 0.71 10.2 0.0 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCH58343.1 - 9.1e-08 32.3 3.4 0.0023 18.2 0.1 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCH58343.1 - 4.1e-06 26.0 1.0 0.15 11.0 0.1 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCH58343.1 - 6.2e-05 22.7 0.0 0.35 10.7 0.0 3.6 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH58343.1 - 0.00026 20.5 11.6 1.6 8.7 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat Dynamin_N PF00350.18 CCH58343.1 - 8.5 6.1 8.6 27 4.5 0.2 3.5 3 0 0 3 3 3 0 Dynamin family UFD1 PF03152.9 CCH58344.1 - 8e-74 246.5 0.1 1.2e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NPR3 PF03666.8 CCH58344.1 - 0.051 12.1 3.6 0.04 12.4 1.5 1.5 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1232 PF06803.7 CCH58344.1 - 0.18 11.3 0.2 0.31 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) DUF2422 PF10337.4 CCH58345.1 - 2.1e-40 138.9 0.6 2.1e-40 138.9 0.4 3.6 3 1 1 4 4 4 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCH58345.1 - 1.3e-11 44.5 8.4 1.3e-11 44.5 5.8 3.3 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CCH58345.1 - 6.7e-09 34.8 3.8 2.7e-05 23.0 0.5 2.5 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 CCH58345.1 - 0.019 14.6 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CCH58346.1 - 1.5e-39 136.0 1.2 1.5e-39 136.0 0.8 3.4 4 1 0 4 4 4 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCH58346.1 - 8.2e-12 45.1 9.0 8.2e-12 45.1 6.3 3.2 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CCH58346.1 - 5.4e-06 25.3 3.1 0.0026 16.4 1.5 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 CCH58346.1 - 0.021 13.2 1.4 0.039 12.3 1.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2421 PF10334.4 CCH58346.1 - 0.038 13.6 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) DUF2422 PF10337.4 CCH58347.1 - 3.9e-45 154.5 3.8 1.9e-43 148.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCH58347.1 - 2.5e-12 46.8 11.5 2.5e-12 46.8 8.0 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 CCH58347.1 - 4.5e-05 23.1 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ACR_tran PF00873.14 CCH58347.1 - 0.03 11.7 0.4 0.052 10.9 0.3 1.3 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FUSC PF04632.7 CCH58347.1 - 1.7 6.9 4.3 3 6.1 3.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CRAL_TRIO PF00650.15 CCH58348.1 - 1.7e-37 128.3 0.0 2.4e-37 127.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH58348.1 - 4.8e-12 45.8 1.6 1.1e-11 44.6 1.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCH58348.1 - 0.00051 19.9 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DnaJ PF00226.26 CCH58349.1 - 2.5e-17 62.3 0.3 5e-17 61.3 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Takusan PF04822.8 CCH58349.1 - 2 8.2 8.1 0.41 10.4 0.7 2.8 1 1 0 2 2 2 0 Takusan YIF1 PF03878.10 CCH58350.1 - 5.4e-75 251.6 9.0 6.8e-75 251.3 6.2 1.1 1 0 0 1 1 1 1 YIF1 DUF1744 PF08490.7 CCH58351.1 - 1e-141 472.1 5.7 1.9e-141 471.2 4.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CCH58351.1 - 2.6e-68 230.2 6.4 2.6e-68 230.2 4.5 2.5 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CCH58351.1 - 2.2e-24 86.1 8.3 3e-23 82.3 2.9 2.5 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CCH58351.1 - 2.5e-07 30.4 1.6 9.9e-07 28.4 0.3 2.6 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCH58351.1 - 0.0003 20.6 0.1 0.0003 20.6 0.0 3.4 5 0 0 5 5 5 1 RNase_H superfamily APP_N PF02177.11 CCH58351.1 - 0.013 15.3 5.8 0.02 14.7 0.3 3.1 3 0 0 3 3 3 0 Amyloid A4 N-terminal heparin-binding PRP1_N PF06424.7 CCH58351.1 - 0.6 10.4 5.3 3 8.1 0.2 3.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal ORC5_C PF14630.1 CCH58352.1 - 2.3e-64 217.4 1.2 2.9e-64 217.1 0.8 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 CCH58352.1 - 1.1e-05 25.4 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain CRAL_TRIO_2 PF13716.1 CCH58352.1 - 0.0049 16.7 0.2 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain ResIII PF04851.10 CCH58352.1 - 0.0065 16.3 0.1 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCH58352.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 CCH58353.1 - 1.3e-12 47.1 5.2 1.3e-12 47.1 3.6 2.1 2 0 0 2 2 2 1 GYF domain Yae1_N PF09811.4 CCH58354.1 - 4.5e-07 29.2 3.5 4.5e-07 29.2 2.4 2.5 2 1 0 2 2 2 1 Essential protein Yae1, N terminal Baculo_p24 PF05073.7 CCH58354.1 - 0.0049 16.4 3.3 0.0068 15.9 2.3 1.2 1 0 0 1 1 1 1 Baculovirus P24 capsid protein Dsl1_C PF11989.3 CCH58355.1 - 3.1e-92 308.8 26.4 3.1e-92 308.8 18.3 3.8 3 1 0 4 4 4 1 Retrograde transport protein Dsl1 C terminal Dsl1_N PF11988.3 CCH58355.1 - 3.8e-81 272.7 25.9 3.8e-81 272.7 18.0 2.1 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 N terminal DUF3246 PF11596.3 CCH58355.1 - 0.93 8.7 7.3 1.9 7.7 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PH PF00169.24 CCH58356.1 - 6.6e-07 29.4 0.3 4.6e-06 26.7 0.2 2.6 1 0 0 1 1 1 1 PH domain PGAP1 PF07819.8 CCH58357.1 - 1.5e-08 34.5 1.9 4e-08 33.1 0.1 2.2 3 0 0 3 3 3 1 PGAP1-like protein DUF676 PF05057.9 CCH58357.1 - 1.1e-06 28.0 0.0 2.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 CCH58357.1 - 4.1e-06 26.0 2.6 0.00011 21.3 0.1 3.5 3 1 1 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 CCH58357.1 - 0.00058 18.9 0.1 0.0014 17.7 0.1 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 CCH58357.1 - 0.0047 16.5 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 CCH58357.1 - 0.015 14.6 0.2 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) FAD_binding_3 PF01494.14 CCH58358.1 - 6.8e-16 58.2 1.3 4.6e-09 35.7 0.0 3.1 2 1 1 3 3 3 3 FAD binding domain SE PF08491.5 CCH58358.1 - 9.1e-05 21.4 0.0 0.00014 20.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 CCH58358.1 - 0.003 16.5 0.1 0.16 10.8 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 CCH58358.1 - 0.0082 15.0 0.0 0.7 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCH58358.1 - 0.019 14.7 0.0 0.047 13.4 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCH58358.1 - 0.037 13.9 0.0 0.081 12.7 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pterin_bind PF00809.17 CCH58359.1 - 1.9e-38 131.9 0.5 5.9e-37 127.0 0.2 2.8 2 1 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 CCH58359.1 - 2.4e-38 130.7 0.1 9.4e-38 128.8 0.0 2.0 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 CCH58359.1 - 1.8e-34 118.2 0.3 5.2e-19 68.4 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase RNA_pol_L PF01193.19 CCH58359.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CCHC PF00098.18 CCH58360.1 - 1.5e-52 173.0 49.3 2.3e-08 33.5 1.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CCH58360.1 - 2.1e-11 43.2 42.7 0.0059 16.2 0.3 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 CCH58360.1 - 1.4e-08 34.3 40.5 0.25 11.0 0.4 7.1 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CCH58360.1 - 6.5e-07 28.7 42.6 0.039 13.4 0.2 7.1 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 CCH58360.1 - 0.00014 21.4 41.3 0.011 15.3 1.1 7.0 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.1 CCH58360.1 - 3.5 7.1 36.1 1.9 8.0 0.1 6.7 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger RTC4 PF14474.1 CCH58361.1 - 1.4e-29 102.5 0.0 6.9e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 RTC4-like domain NosD PF05048.8 CCH58361.1 - 0.87 8.6 16.8 2.6 7.1 11.2 2.0 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) WD40 PF00400.27 CCH58362.1 - 2.5e-17 62.0 3.8 2e-07 30.5 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat MMS1_N PF10433.4 CCH58362.1 - 0.0002 19.6 0.9 0.0079 14.3 0.1 2.8 1 1 2 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactonase PF10282.4 CCH58362.1 - 0.016 14.2 0.0 1.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Hira PF07569.6 CCH58362.1 - 0.046 12.9 0.1 9.7 5.3 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split MRP-L46 PF11788.3 CCH58363.1 - 9.2e-39 132.5 1.1 1.6e-38 131.7 0.4 1.6 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 RRM_1 PF00076.17 CCH58364.1 - 0.00024 20.6 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58364.1 - 0.00036 20.4 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 CCH58364.1 - 0.01 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 SDP_N PF12278.3 CCH58364.1 - 0.021 14.4 4.5 0.051 13.2 3.1 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal CTK3 PF12243.3 CCH58364.1 - 0.038 13.6 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 CCH58364.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.1 CCH58365.1 - 3.9e-27 95.9 0.5 3.9e-27 95.9 0.4 8.9 2 1 4 6 6 6 1 AAA domain Rad50_zn_hook PF04423.9 CCH58365.1 - 5.2e-12 45.0 0.5 5.2e-12 45.0 0.4 6.1 4 0 0 4 4 4 1 Rad50 zinc hook motif SbcCD_C PF13558.1 CCH58365.1 - 1.3e-11 44.2 0.1 4.9e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CCH58365.1 - 4.7e-07 28.6 161.8 0.00021 19.9 0.0 6.7 2 1 3 5 5 5 3 AAA domain SMC_N PF02463.14 CCH58365.1 - 6.6e-06 25.5 0.1 6.6e-06 25.5 0.1 4.0 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCH58365.1 - 0.003 17.5 0.0 0.003 17.5 0.0 7.2 2 1 2 4 4 4 2 AAA domain AAA_29 PF13555.1 CCH58365.1 - 0.0068 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CCH58365.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF3534 PF12053.3 CCH58365.1 - 0.6 9.9 5.6 1 9.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3534) RNA_pol_I_A49 PF06870.7 CCH58366.1 - 4.5e-131 436.9 1.1 5.2e-131 436.7 0.7 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DnaJ PF00226.26 CCH58367.1 - 7.6e-17 60.8 2.7 2e-16 59.4 1.9 1.7 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CCH58367.1 - 4.6e-13 48.4 3.5 7.6e-13 47.7 2.5 1.4 1 0 0 1 1 1 1 CSL zinc finger DUF3133 PF11331.3 CCH58367.1 - 0.08 12.5 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) zinc_ribbon_5 PF13719.1 CCH58367.1 - 0.35 10.5 3.2 12 5.6 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 CCH58367.1 - 0.42 10.9 2.6 0.74 10.1 1.4 1.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.1 CCH58367.1 - 0.5 10.1 3.7 13 5.5 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Abhydrolase_1 PF00561.15 CCH58368.1 - 2.2e-07 30.6 0.0 4.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCH58368.1 - 7.3e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCH58368.1 - 4.9e-06 26.3 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 CCH58368.1 - 7.4e-06 25.1 0.0 2.7e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 CCH58368.1 - 0.0013 18.1 0.1 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 CCH58368.1 - 0.0021 17.8 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family tRNA-synt_1e PF01406.14 CCH58369.1 - 3.5e-141 469.6 0.7 7.3e-141 468.5 0.5 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CCH58369.1 - 7.8e-10 37.9 1.2 1e-06 27.6 0.1 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.13 CCH58369.1 - 0.0011 17.7 0.2 0.0029 16.3 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF708 PF05341.6 CCH58369.1 - 0.017 14.8 0.5 1.2 8.9 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF708) NAP PF00956.13 CCH58370.1 - 2.6e-22 79.1 4.7 3.1e-22 78.8 3.3 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) TFIIE-A_C-term PF11521.3 CCH58370.1 - 0.069 13.0 0.1 0.069 13.0 0.1 1.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Cir_N PF10197.4 CCH58371.1 - 1.3e-08 34.6 9.8 2.9e-08 33.5 6.8 1.6 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 CCH58371.1 - 3.8e-08 33.6 3.3 3.8e-08 33.6 2.3 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor RCC_reductase PF06405.6 CCH58371.1 - 0.053 12.4 0.6 0.07 12.0 0.4 1.2 1 0 0 1 1 1 0 Red chlorophyll catabolite reductase (RCC reductase) DUF2590 PF10761.4 CCH58371.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2590) SUI1 PF01253.17 CCH58372.1 - 2.2e-28 97.8 3.4 2.8e-28 97.5 2.4 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mito_carr PF00153.22 CCH58373.1 - 9.1e-56 185.5 0.4 3.7e-17 61.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arylesterase PF01731.15 CCH58374.1 - 0.083 12.8 0.2 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Arylesterase zf-C3HC4_4 PF15227.1 CCH58374.1 - 1.1 9.1 13.3 2.5 8.0 9.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CCH58374.1 - 5 7.2 18.0 1.7 8.7 10.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4041 PF13250.1 CCH58374.1 - 6.6 6.3 7.6 0.7 9.4 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Endonuclease_NS PF01223.18 CCH58376.1 - 7.5e-58 195.5 0.0 1e-57 195.1 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Fungal_trans PF04082.13 CCH58378.1 - 4.5e-19 68.3 11.3 4.5e-19 68.3 7.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH58378.1 - 3.6e-08 33.1 10.0 6.6e-08 32.3 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tir_receptor_C PF07489.6 CCH58378.1 - 1.2 8.8 5.8 2.5 7.8 4.0 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Zn_clus PF00172.13 CCH58379.1 - 7.9e-05 22.4 11.9 0.00014 21.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2665 PF11654.3 CCH58380.1 - 2e-13 49.6 0.1 2.3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) RNase_H2_suC PF08615.6 CCH58381.1 - 7.7e-11 41.9 0.9 4.5e-10 39.5 0.6 1.9 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) EAF PF09816.4 CCH58381.1 - 0.033 14.1 0.9 0.051 13.5 0.6 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor FleQ PF06490.6 CCH58381.1 - 0.048 13.7 0.2 0.067 13.3 0.1 1.1 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Prenyltransf PF01255.14 CCH58382.1 - 0.0005 19.2 0.1 0.0012 17.9 0.1 1.8 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4261 PF14080.1 CCH58382.1 - 0.029 14.1 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Arf PF00025.16 CCH58383.1 - 1.5e-77 258.7 0.0 1.7e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCH58383.1 - 2.3e-14 53.0 0.0 2.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCH58383.1 - 6.2e-14 51.6 0.0 7.5e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCH58383.1 - 4.7e-11 42.0 0.6 4.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCH58383.1 - 8.6e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCH58383.1 - 1.5e-10 41.6 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCH58383.1 - 8.8e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCH58383.1 - 0.0059 16.0 0.0 0.032 13.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CCH58383.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CCH58383.1 - 0.0071 16.2 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCH58383.1 - 0.021 14.5 0.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CCH58383.1 - 0.033 14.4 0.1 0.063 13.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CCH58383.1 - 0.037 13.0 0.1 0.054 12.5 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 CCH58383.1 - 0.075 12.4 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Metallophos PF00149.23 CCH58384.1 - 4.2e-40 137.2 0.5 4.2e-40 137.2 0.4 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Mit_KHE1 PF10173.4 CCH58385.1 - 5.8e-56 189.3 6.0 1e-55 188.5 4.1 1.4 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Cullin PF00888.17 CCH58386.1 - 3.4e-159 531.1 17.9 3.4e-159 531.1 12.4 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CCH58386.1 - 6.9e-25 86.6 0.9 3.1e-24 84.5 0.6 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain Phage_rep_O PF04492.8 CCH58386.1 - 0.00044 20.4 1.4 0.54 10.4 0.0 3.2 3 0 0 3 3 3 2 Bacteriophage replication protein O HMGL-like PF00682.14 CCH58387.1 - 3e-72 243.1 0.5 5.4e-72 242.2 0.1 1.6 2 0 0 2 2 2 1 HMGL-like Trp_syntA PF00290.15 CCH58387.1 - 0.022 13.2 0.0 3 6.2 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Ribosomal_60s PF00428.14 CCH58388.1 - 6e-23 81.0 16.6 7.3e-23 80.7 11.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Microvir_H PF04687.7 CCH58388.1 - 4.1 6.3 7.0 4.5 6.2 4.8 1.0 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) ABC_tran PF00005.22 CCH58390.1 - 3.4e-48 163.4 0.0 3.3e-25 88.9 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCH58390.1 - 2.7e-15 57.1 13.7 6.5e-06 26.3 0.0 5.5 5 1 0 5 5 5 3 AAA domain SMC_N PF02463.14 CCH58390.1 - 5.1e-14 52.0 0.0 8.2e-05 21.9 0.0 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH58390.1 - 4.2e-08 32.6 0.3 0.01 15.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCH58390.1 - 4.7e-07 30.6 0.1 0.059 14.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain Chromo PF00385.19 CCH58390.1 - 5.1e-07 29.2 3.6 1.2e-06 28.0 2.5 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF258 PF03193.11 CCH58390.1 - 1.9e-06 27.1 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCH58390.1 - 2.2e-06 27.6 0.0 0.041 13.8 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_28 PF13521.1 CCH58390.1 - 4.2e-06 26.8 0.1 0.14 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CCH58390.1 - 1e-05 25.6 0.0 0.053 13.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CCH58390.1 - 2.2e-05 24.9 0.0 0.17 12.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 CCH58390.1 - 3.1e-05 24.3 0.0 0.002 18.4 0.0 4.3 5 1 0 5 5 3 2 AAA domain AAA_10 PF12846.2 CCH58390.1 - 6.1e-05 22.5 4.8 0.28 10.5 0.0 4.4 4 1 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 CCH58390.1 - 0.00023 21.0 0.7 1.8 8.5 0.0 4.0 2 2 1 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CCH58390.1 - 0.00037 20.6 0.1 2.8 8.1 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCH58390.1 - 0.00046 20.5 0.5 0.13 12.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CCH58390.1 - 0.00049 19.7 1.1 0.66 9.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain HEAT_2 PF13646.1 CCH58390.1 - 0.0005 20.3 0.4 2.2 8.6 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats ArgK PF03308.11 CCH58390.1 - 0.00059 18.6 1.5 0.54 8.9 0.0 2.6 3 0 0 3 3 2 2 ArgK protein RNA_helicase PF00910.17 CCH58390.1 - 0.00076 19.6 0.0 2.6 8.2 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.1 CCH58390.1 - 0.00084 18.9 0.6 0.97 8.9 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CCH58390.1 - 0.00098 19.0 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 CCH58390.1 - 0.0011 18.8 10.9 0.039 13.7 0.0 5.4 5 1 0 5 5 5 1 Domain of unknown function DUF87 MobB PF03205.9 CCH58390.1 - 0.0011 18.6 0.0 0.83 9.3 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CCH58390.1 - 0.0037 17.1 0.0 1.3 8.8 0.0 3.9 3 0 0 3 3 3 1 Dynamin family AAA_14 PF13173.1 CCH58390.1 - 0.01 15.7 0.0 2 8.3 0.0 3.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCH58390.1 - 0.019 14.4 0.3 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 CCH58390.1 - 0.021 14.8 0.5 1.6 8.6 0.0 3.2 3 1 1 4 4 3 0 AAA ATPase domain Zeta_toxin PF06414.7 CCH58390.1 - 0.022 13.8 0.3 6.3 5.8 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 CCH58390.1 - 0.032 13.6 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 CCH58390.1 - 0.04 13.3 0.9 2.7 7.3 0.0 3.6 4 0 0 4 4 3 0 Thymidylate kinase NTPase_1 PF03266.10 CCH58390.1 - 0.063 12.9 0.1 9 5.9 0.0 2.9 3 0 0 3 3 3 0 NTPase cobW PF02492.14 CCH58390.1 - 0.064 12.6 0.1 20 4.5 0.0 3.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 CCH58390.1 - 0.081 12.3 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V PduV-EutP PF10662.4 CCH58390.1 - 0.089 12.2 0.1 12 5.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MoCF_biosynth PF00994.19 CCH58391.1 - 8.8e-33 112.7 0.0 2.7e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain Polysacc_synt_4 PF04669.8 CCH58392.1 - 2.4e-22 79.2 1.2 1.9e-21 76.2 0.8 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF1943 PF09172.6 CCH58392.1 - 0.036 12.9 0.1 0.048 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Phe_ZIP PF08916.6 CCH58392.1 - 0.16 12.2 3.0 21 5.5 0.0 3.2 2 1 1 3 3 3 0 Phenylalanine zipper Cation_efflux PF01545.16 CCH58393.1 - 3.3e-42 144.4 4.8 5.3e-42 143.8 3.3 1.3 1 0 0 1 1 1 1 Cation efflux family UreE_C PF05194.7 CCH58393.1 - 3.6 7.7 13.7 6.1 7.0 1.5 3.5 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain LMWPc PF01451.16 CCH58394.1 - 3.9e-38 130.8 0.0 4.4e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase GCR1_C PF12550.3 CCH58396.1 - 2.2e-24 85.1 2.5 4.6e-24 84.0 1.7 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes UPF0061 PF02696.9 CCH58397.1 - 5e-95 318.6 0.3 6.5e-95 318.2 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TrbM PF07424.6 CCH58397.1 - 0.022 14.7 1.5 0.061 13.2 1.0 1.8 1 1 1 2 2 2 0 TrbM TRP PF06011.7 CCH58398.1 - 1.2e-107 360.1 39.0 1.7e-107 359.7 27.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCH58398.1 - 1.5e-35 122.3 0.0 4e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 ML-like domain TFIIF_alpha PF05793.7 CCH58398.1 - 1.4 7.1 11.0 2.1 6.6 7.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coatomer_WDAD PF04053.9 CCH58399.1 - 1.9e-154 514.7 0.2 3.2e-154 513.9 0.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CCH58399.1 - 7.3e-47 155.6 9.1 5e-11 42.0 0.0 8.0 7 1 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCH58399.1 - 1.2e-05 25.0 0.0 0.33 10.7 0.0 4.5 3 1 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region TPR_2 PF07719.12 CCH58399.1 - 0.00035 20.2 6.9 1.1 9.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCH58399.1 - 0.0072 15.8 3.0 8.8 6.1 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Nup160 PF11715.3 CCH58399.1 - 0.023 12.8 1.4 4.5 5.2 0.0 3.5 3 1 0 4 4 4 0 Nucleoporin Nup120/160 TPR_8 PF13181.1 CCH58399.1 - 0.054 13.3 0.5 21 5.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCH58399.1 - 0.2 11.3 10.0 0.46 10.1 0.0 3.9 3 1 1 4 4 4 0 TPR repeat FtsJ PF01728.14 CCH58400.1 - 1.5e-53 181.4 0.0 2.1e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CCH58400.1 - 1.4e-05 24.8 0.0 4.7e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH58400.1 - 0.00087 18.9 0.4 0.93 9.0 0.1 2.9 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 CCH58400.1 - 0.0058 17.1 0.0 0.019 15.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L1 PF00687.16 CCH58401.1 - 5.2e-46 156.7 1.6 6.5e-46 156.4 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Arf PF00025.16 CCH58402.1 - 7.9e-67 223.8 0.0 8.8e-67 223.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCH58402.1 - 2.8e-09 37.4 0.0 4.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CCH58402.1 - 3.7e-09 35.7 0.9 4.5e-06 25.6 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CCH58402.1 - 6.9e-09 35.3 0.0 8.6e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCH58402.1 - 1.1e-07 31.2 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCH58402.1 - 4.1e-06 26.7 0.0 5.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCH58402.1 - 0.00011 21.3 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH58402.1 - 0.00057 19.3 0.1 0.011 15.2 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCH58402.1 - 0.043 13.2 0.0 0.15 11.5 0.0 1.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF663 PF04950.7 CCH58403.1 - 1.2e-104 349.4 0.2 1.2e-104 349.4 0.2 2.4 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCH58403.1 - 2.2e-29 100.8 0.0 6.3e-29 99.3 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CCH58403.1 - 2.5e-08 33.5 0.0 1.6e-05 24.4 0.0 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 CCH58403.1 - 3.9e-06 26.5 0.3 9.4e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CCH58403.1 - 3.9e-06 27.0 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCH58403.1 - 7.4e-06 25.8 0.0 3.3e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH58403.1 - 8.4e-06 25.9 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH58403.1 - 1.8e-05 25.5 0.0 1.8e-05 25.5 0.0 3.9 3 1 0 4 4 3 1 AAA domain MobB PF03205.9 CCH58403.1 - 5.2e-05 22.9 0.3 0.0002 21.0 0.2 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCH58403.1 - 5.9e-05 23.1 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CCH58403.1 - 0.00063 19.4 0.6 0.0015 18.2 0.1 1.9 2 1 0 2 2 1 1 NACHT domain MMR_HSR1 PF01926.18 CCH58403.1 - 0.00077 19.4 0.3 0.005 16.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CCH58403.1 - 0.0012 19.2 0.0 0.0061 17.0 0.0 2.3 2 0 0 2 2 1 1 Miro-like protein AAA_25 PF13481.1 CCH58403.1 - 0.0022 17.4 0.0 0.0063 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCH58403.1 - 0.003 17.1 0.1 0.0097 15.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCH58403.1 - 0.0031 17.6 0.0 0.0085 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 CCH58403.1 - 0.0053 16.4 0.4 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 NTPase AAA_28 PF13521.1 CCH58403.1 - 0.0091 15.9 1.4 0.015 15.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 CCH58403.1 - 0.0098 16.1 0.0 0.0098 16.1 0.0 2.9 4 0 0 4 4 3 1 ABC transporter cobW PF02492.14 CCH58403.1 - 0.012 15.0 0.2 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCH58403.1 - 0.013 15.7 0.0 0.013 15.7 0.0 4.5 4 2 0 4 4 2 0 AAA domain AAA_5 PF07728.9 CCH58403.1 - 0.016 14.9 0.1 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CCH58403.1 - 0.024 14.1 0.0 0.024 14.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 CCH58403.1 - 0.067 12.6 0.0 0.65 9.4 0.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mg_chelatase PF01078.16 CCH58403.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI HK PF02110.10 CCH58404.1 - 9.4e-84 280.4 0.8 1.3e-83 280.0 0.5 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CCH58404.1 - 7.6e-57 191.3 0.0 1.2e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 CCH58404.1 - 0.055 12.6 1.0 0.6 9.2 0.4 2.6 2 1 0 2 2 2 0 Phosphomethylpyrimidine kinase NMO PF03060.10 CCH58404.1 - 0.088 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase LRR_9 PF14580.1 CCH58405.1 - 5.7e-14 52.0 1.0 8.9e-14 51.4 0.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCH58405.1 - 1e-07 31.3 24.2 8e-05 22.1 1.4 4.0 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH58405.1 - 0.00012 21.7 16.9 0.0022 17.7 4.0 4.2 3 1 3 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 CCH58405.1 - 0.014 15.3 22.0 0.93 9.7 0.7 5.2 4 2 1 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CCH58405.1 - 0.024 14.7 19.2 0.73 10.2 0.8 5.9 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CCH58405.1 - 6.8 7.1 18.8 11 6.4 1.8 5.4 3 1 2 5 5 5 0 Leucine Rich repeat BAH PF01426.13 CCH58406.1 - 9.4e-15 54.4 0.2 2.8e-14 52.8 0.2 1.9 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 CCH58406.1 - 3.3e-14 52.8 4.6 3.3e-14 52.8 3.2 4.5 3 1 0 3 3 3 2 PHD-zinc-finger like domain PHD PF00628.24 CCH58406.1 - 1.1e-09 37.8 49.9 2.3e-05 23.9 9.2 5.0 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.1 CCH58406.1 - 7.8e-06 25.1 31.6 4.2e-05 22.7 3.6 5.3 5 0 0 5 5 5 3 PHD-finger C1_1 PF00130.17 CCH58406.1 - 0.59 9.9 47.8 0.19 11.4 3.6 5.8 4 1 1 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PseudoU_synth_1 PF01416.15 CCH58407.1 - 6e-20 71.6 0.0 1.3e-08 35.2 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0113 PF03657.8 CCH58408.1 - 3.7e-13 49.4 0.0 4.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) SRP72 PF08492.7 CCH58409.1 - 3.8e-11 43.1 6.2 3.8e-11 43.1 4.3 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 CCH58409.1 - 1.7e-06 27.8 5.2 0.00085 19.2 0.3 4.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCH58409.1 - 0.0015 18.2 9.9 0.15 12.0 0.6 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCH58409.1 - 0.0017 17.9 7.7 0.0085 15.7 0.1 3.6 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 CCH58409.1 - 0.0026 18.0 1.2 21 5.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCH58409.1 - 0.19 12.4 0.3 23 5.8 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCH58409.1 - 0.21 12.3 0.3 72 4.4 0.0 3.8 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCH58409.1 - 0.28 11.0 4.5 1.3 9.0 0.2 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCH58409.1 - 0.3 11.2 7.4 1.1 9.4 0.1 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCH58409.1 - 1.2 9.7 3.9 4.4e+02 1.7 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCH58409.1 - 2.9 7.6 9.1 4.7 6.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.24 CCH58410.1 - 2.5e-27 95.4 0.1 9e-27 93.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH58410.1 - 1.9e-15 56.5 0.0 3.8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH58410.1 - 2.7e-09 37.1 1.1 4.2e-09 36.4 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCH58410.1 - 2.4e-07 29.8 0.0 4.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 CCH58410.1 - 0.055 12.7 0.1 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain SET PF00856.23 CCH58411.1 - 0.00012 22.4 0.6 0.00028 21.2 0.1 1.9 2 0 0 2 2 2 1 SET domain DUF676 PF05057.9 CCH58414.1 - 1.7e-51 174.5 0.5 2.6e-51 174.0 0.3 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCH58414.1 - 1.9e-05 24.3 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Pex24p PF06398.6 CCH58414.1 - 0.0075 15.0 0.3 0.0075 15.0 0.2 1.5 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin Abhydrolase_5 PF12695.2 CCH58414.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PolyA_pol PF01743.15 CCH58415.1 - 0.041 14.1 3.3 0.18 12.0 2.3 1.9 1 1 0 1 1 1 0 Poly A polymerase head domain GAGA_bind PF06217.7 CCH58415.1 - 0.23 11.3 6.3 0.3 10.9 4.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Plasmodium_Vir PF05795.6 CCH58415.1 - 0.37 9.9 3.6 0.51 9.4 2.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_BLLF1 PF05109.8 CCH58415.1 - 1.3 6.8 26.9 1.7 6.4 18.7 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-RING_2 PF13639.1 CCH58416.1 - 0.0008 19.1 9.1 0.0016 18.2 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH58416.1 - 0.68 10.0 10.2 1.9 8.5 7.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH58416.1 - 4.1 7.1 10.6 12 5.6 7.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 6PF2K PF01591.13 CCH58417.1 - 1.7e-61 207.1 1.6 2.7e-61 206.4 1.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCH58417.1 - 4e-31 108.2 1.0 6.2e-31 107.6 0.0 1.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCH58417.1 - 5.4e-06 26.3 0.0 1.3e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCH58417.1 - 6.3e-05 22.3 0.2 0.00013 21.3 0.1 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CCH58417.1 - 0.019 15.7 0.2 0.18 12.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain Vps35 PF03635.12 CCH58418.1 - 1.2e-165 552.8 47.0 8.6e-93 311.8 16.2 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 Adeno_terminal PF02459.10 CCH58419.1 - 0.005 15.0 1.5 0.0062 14.7 0.7 1.4 1 1 0 1 1 1 1 Adenoviral DNA terminal protein HrcA_DNA-bdg PF03444.10 CCH58419.1 - 0.024 14.0 1.3 0.024 14.0 0.9 1.7 2 0 0 2 2 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF1312 PF07009.6 CCH58419.1 - 0.51 10.1 3.8 0.28 11.0 1.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1312) Avl9 PF09794.4 CCH58419.1 - 1.8 6.9 8.1 1.3 7.4 1.1 2.0 1 1 1 2 2 2 0 Transport protein Avl9 DUF4050 PF13259.1 CCH58420.1 - 4.1e-12 46.0 0.4 4.1e-12 46.0 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) Rxt3 PF08642.5 CCH58421.1 - 2.7e-29 101.7 1.6 3.7e-29 101.3 0.1 1.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 CCH58421.1 - 0.00093 19.1 0.1 2.1 8.4 0.0 3.3 3 1 0 3 3 3 2 LCCL domain Ribosomal_L31e PF01198.14 CCH58422.1 - 7.2e-38 128.1 1.2 8.6e-38 127.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Dus PF01207.12 CCH58423.1 - 2e-71 240.3 0.0 2.4e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) B12-binding PF02310.14 CCH58423.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain BRE1 PF08647.6 CCH58424.1 - 1.6e-27 95.2 14.3 1.6e-27 95.2 9.9 5.7 3 3 2 5 5 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 CCH58424.1 - 6e-06 26.1 13.3 1.1e-05 25.2 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH58424.1 - 7.7e-06 25.4 11.2 1.5e-05 24.5 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH58424.1 - 1.9e-05 24.2 13.2 3.9e-05 23.3 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCH58424.1 - 0.00014 21.4 14.9 0.00015 21.3 9.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH58424.1 - 0.002 17.9 10.7 0.0038 17.0 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CCH58424.1 - 0.0032 16.9 5.2 0.0066 15.9 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CCH58424.1 - 0.041 13.6 4.8 0.092 12.5 3.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCH58424.1 - 0.27 10.9 10.4 0.39 10.4 5.5 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-C2H2 PF00096.21 CCH58424.1 - 0.38 11.1 0.1 0.38 11.1 0.1 3.2 4 0 0 4 4 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.1 CCH58424.1 - 7.6 6.2 10.9 15 5.2 7.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Bap31 PF05529.7 CCH58425.1 - 1.3e-43 148.6 0.1 1.6e-43 148.3 0.1 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 CCH58425.1 - 0.096 12.4 0.4 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding T2SM PF04612.7 CCH58425.1 - 0.87 9.3 5.5 2.4 7.9 0.8 2.4 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein M Bromodomain PF00439.20 CCH58426.1 - 3.5e-39 132.6 3.5 7.1e-19 67.5 0.4 2.9 2 0 0 2 2 2 2 Bromodomain Macoilin PF09726.4 CCH58426.1 - 0.00042 18.7 0.0 0.00042 18.7 0.0 4.0 2 1 2 4 4 4 1 Transmembrane protein DSHCT PF08148.7 CCH58427.1 - 5.5e-61 204.9 1.0 9.1e-61 204.2 0.2 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CCH58427.1 - 5.7e-23 81.2 0.1 1.5e-22 79.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CCH58427.1 - 4.1e-09 35.9 0.6 1.4e-08 34.2 0.4 1.9 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CCH58427.1 - 6.7e-07 29.0 0.0 2.3e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA PF00004.24 CCH58429.1 - 1.5e-92 306.7 0.0 8.8e-45 152.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCH58429.1 - 1.1e-12 47.4 0.0 5.3e-05 22.3 0.0 3.1 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCH58429.1 - 1e-11 45.0 0.0 0.00013 21.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCH58429.1 - 3.8e-11 43.2 0.2 2.4e-05 24.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCH58429.1 - 4e-11 42.9 0.0 2.9e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCH58429.1 - 5.6e-11 42.3 0.0 0.00074 19.2 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH58429.1 - 6.6e-11 42.5 0.0 8.5e-05 22.6 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CCH58429.1 - 1.4e-06 28.2 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CCH58429.1 - 1.7e-06 27.0 0.0 0.0042 15.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 CCH58429.1 - 2.2e-06 28.5 0.4 0.032 15.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 CCH58429.1 - 3.7e-06 27.0 0.0 0.16 12.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 CCH58429.1 - 3.4e-05 23.1 0.1 0.093 11.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CCH58429.1 - 3.9e-05 23.7 0.0 0.086 12.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 CCH58429.1 - 0.00011 22.2 0.0 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCH58429.1 - 0.00012 21.8 0.0 0.25 11.0 0.0 3.0 2 1 1 3 3 3 2 Archaeal ATPase AAA_25 PF13481.1 CCH58429.1 - 0.00017 21.0 4.2 1.8 7.9 0.1 4.0 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 CCH58429.1 - 0.00042 19.4 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Bac_DnaA PF00308.13 CCH58429.1 - 0.00075 19.2 0.0 0.0067 16.0 0.0 2.3 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_19 PF13245.1 CCH58429.1 - 0.00091 18.9 7.0 0.0089 15.7 0.1 3.5 4 0 0 4 4 3 1 Part of AAA domain IstB_IS21 PF01695.12 CCH58429.1 - 0.001 18.5 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.10 CCH58429.1 - 0.0013 17.5 0.0 0.05 12.2 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 CCH58429.1 - 0.0029 17.2 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCH58429.1 - 0.0031 17.1 0.1 0.079 12.6 0.0 3.0 4 0 0 4 4 4 1 NACHT domain Viral_helicase1 PF01443.13 CCH58429.1 - 0.0081 15.6 0.0 0.029 13.8 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 CCH58429.1 - 0.01 16.1 0.0 7.2 6.8 0.0 2.7 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCH58429.1 - 0.012 15.9 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 CCH58429.1 - 0.012 15.1 0.0 0.67 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CCH58429.1 - 0.014 14.8 0.0 6.1 6.2 0.0 3.6 2 2 1 3 3 3 0 Sigma-54 interaction domain CDC48_N PF02359.13 CCH58429.1 - 0.019 14.8 0.2 0.055 13.4 0.1 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.1 CCH58429.1 - 0.024 14.9 1.4 0.97 9.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CCH58429.1 - 0.027 14.0 0.2 5.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CCH58429.1 - 0.03 13.1 0.0 0.13 11.0 0.0 2.0 3 0 0 3 3 3 0 AFG1-like ATPase UPF0079 PF02367.12 CCH58429.1 - 0.032 13.8 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ATP-synt_ab PF00006.20 CCH58429.1 - 0.036 13.5 0.0 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 CCH58429.1 - 0.041 12.9 0.1 14 4.6 0.0 3.1 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.1 CCH58429.1 - 0.063 12.8 0.8 0.9 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain FSH1 PF03959.8 CCH58430.1 - 0.038 13.4 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COX7C PF02935.11 CCH58431.1 - 1.3e-20 72.9 1.5 1.4e-20 72.8 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc RRM_1 PF00076.17 CCH58432.1 - 3.7e-12 45.7 0.1 7.5e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58432.1 - 6.3e-06 26.0 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58432.1 - 0.00059 19.6 0.1 0.00093 19.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myco_19_kDa PF05481.7 CCH58432.1 - 3.6 7.3 8.2 0.13 12.0 1.4 1.7 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen SPA PF08616.5 CCH58433.1 - 5.7e-12 45.3 3.1 5.7e-12 45.3 2.1 2.8 3 0 0 3 3 3 1 Stabilization of polarity axis Afi1 PF07792.7 CCH58433.1 - 1.7e-05 24.8 0.0 1.7e-05 24.8 0.0 5.1 4 2 0 4 4 4 1 Docking domain of Afi1 for Arf3 in vesicle trafficking TPP_enzyme_N PF02776.13 CCH58434.1 - 3.1e-32 111.4 0.0 4.4e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCH58434.1 - 2.2e-18 66.3 0.0 3.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCH58434.1 - 3.5e-12 46.1 0.0 7.7e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Complex1_LYR PF05347.10 CCH58435.1 - 2.4e-15 56.0 0.4 2.9e-15 55.8 0.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCH58435.1 - 1.1e-11 44.7 0.3 1.3e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.22 CCH58436.1 - 2e-43 147.6 0.8 5.1e-43 146.3 0.6 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CCH58436.1 - 1.3e-11 44.3 25.4 1.6e-06 28.0 7.3 2.5 2 0 0 2 2 2 2 LIM domain LSM PF01423.17 CCH58437.1 - 4.7e-17 61.3 0.0 5.4e-17 61.1 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCH58437.1 - 0.00017 21.4 0.0 0.00021 21.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CCH58437.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain F1F0-ATPsyn_F PF10791.4 CCH58438.1 - 1.9e-34 117.7 0.1 2.1e-34 117.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi UCH PF00443.24 CCH58439.1 - 3e-60 203.6 9.0 3e-60 203.6 6.2 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CCH58439.1 - 1.4e-40 136.4 15.7 5e-19 67.4 0.1 5.2 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 CCH58439.1 - 1.1e-10 41.4 19.0 2.8e-06 26.9 1.6 4.1 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Col_cuticle_N PF01484.12 CCH58439.1 - 0.03 14.0 0.1 0.1 12.3 0.1 1.9 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain GPP34 PF05719.6 CCH58440.1 - 4.2e-60 203.3 0.0 5.4e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PUF PF00806.14 CCH58440.1 - 0.094 12.2 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Leucyl-specific PF14795.1 CCH58440.1 - 0.26 11.1 1.0 1.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Leo1 PF04004.8 CCH58441.1 - 3.7e-43 147.2 0.4 3.7e-43 147.2 0.2 2.8 2 0 0 2 2 2 1 Leo1-like protein Myb_DNA-bind_2 PF08914.6 CCH58441.1 - 0.00026 20.7 0.4 0.00099 18.8 0.3 2.1 1 0 0 1 1 1 1 Rap1 Myb domain Profilin PF00235.14 CCH58442.1 - 8.1e-35 119.5 0.0 9.7e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Profilin Aldo_ket_red PF00248.16 CCH58443.1 - 7.1e-55 185.8 0.0 8.3e-55 185.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Kei1 PF08552.6 CCH58444.1 - 7.9e-43 146.3 11.4 1.8e-36 125.5 3.8 2.0 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 TLD PF07534.11 CCH58445.1 - 7.6e-28 97.2 1.2 2.3e-25 89.2 0.5 2.4 1 1 1 2 2 2 2 TLD NUC153 PF08159.7 CCH58446.1 - 1.7e-13 49.9 12.5 8.8e-13 47.6 1.8 3.1 3 0 0 3 3 3 2 NUC153 domain YL1 PF05764.8 CCH58447.1 - 0.0056 16.3 9.1 0.0056 16.3 6.3 1.5 2 0 0 2 2 2 1 YL1 nuclear protein AT_hook PF02178.14 CCH58447.1 - 0.14 11.8 5.4 0.5 10.2 3.7 2.0 1 0 0 1 1 1 0 AT hook motif SDA1 PF05285.7 CCH58447.1 - 0.21 10.8 11.5 0.35 10.1 7.9 1.3 1 0 0 1 1 1 0 SDA1 BCIP PF13862.1 CCH58448.1 - 8.2e-53 178.8 0.6 1.4e-52 178.0 0.4 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF2574 PF10836.3 CCH58448.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) VHS PF00790.14 CCH58449.1 - 2.9e-40 137.1 0.7 9.9e-40 135.4 0.0 2.2 2 1 1 3 3 3 1 VHS domain Alpha_adaptinC2 PF02883.15 CCH58449.1 - 1.3e-22 80.2 2.7 1.3e-22 80.2 1.9 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.9 CCH58449.1 - 3.1e-05 23.8 2.8 3.4e-05 23.7 0.4 2.3 3 0 0 3 3 3 1 GAT domain Glycos_transf_3 PF00591.16 CCH58450.1 - 2.4e-73 246.6 0.0 3.5e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CCH58450.1 - 1.2e-09 37.5 0.0 3.2e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Vac_ImportDeg PF09783.4 CCH58451.1 - 4.8e-63 211.8 4.0 7.3e-63 211.2 2.7 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein DNA_pol3_a_NI PF14480.1 CCH58451.1 - 0.017 14.7 0.9 0.98 9.1 0.0 3.3 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus I KilA-N PF04383.8 CCH58451.1 - 0.045 13.3 0.2 0.13 11.9 0.1 1.8 1 1 0 1 1 1 0 KilA-N domain DUF3724 PF12521.3 CCH58451.1 - 0.082 12.6 2.0 0.27 10.9 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) UPF0139 PF03669.8 CCH58452.1 - 0.00029 20.2 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0139) dCMP_cyt_deam_1 PF00383.17 CCH58453.1 - 1.3e-21 76.1 0.0 1.8e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCH58453.1 - 0.0027 17.5 0.1 0.0045 16.8 0.1 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 CCH58453.1 - 0.091 12.3 0.1 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 CCH58453.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase DnaJ PF00226.26 CCH58454.1 - 1.7e-09 37.2 3.8 3.4e-09 36.3 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 CCH58455.1 - 1.4e-57 191.3 0.3 2.5e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.7 CCH58456.1 - 8.8e-24 83.3 5.8 1.7e-23 82.4 4.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH58456.1 - 2.1e-15 56.4 0.0 3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCH58456.1 - 2.4e-05 23.5 0.3 4.9e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CCH58456.1 - 0.064 13.0 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sec8_exocyst PF04048.9 CCH58457.1 - 1.3e-44 151.2 1.5 1.3e-44 151.2 1.0 3.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CCH58457.1 - 8.8e-08 31.3 2.5 8.8e-08 31.3 1.7 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Pkinase PF00069.20 CCH58458.1 - 1.2e-26 93.4 0.1 2.4e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58458.1 - 3.7e-09 36.0 0.0 5.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 CCH58458.1 - 2.8e-07 30.0 13.8 1.7 8.9 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 CCH58458.1 - 0.00012 22.2 0.0 0.34 11.2 0.0 3.6 2 1 1 3 3 3 2 HEAT repeats Kinase-like PF14531.1 CCH58458.1 - 0.0015 17.5 0.0 0.0029 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like WD40 PF00400.27 CCH58458.1 - 0.0023 17.7 10.5 0.022 14.6 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat APH_6_hur PF04655.9 CCH58458.1 - 0.46 9.5 0.0 1.2 8.1 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase PF00069.20 CCH58459.1 - 2.5e-63 213.6 0.0 3.7e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58459.1 - 2.1e-28 99.1 0.0 3.3e-28 98.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L19 PF01245.15 CCH58460.1 - 3.8e-08 33.1 0.9 5.7e-08 32.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 DUF3104 PF11302.3 CCH58460.1 - 0.084 12.2 0.0 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) HIG_1_N PF04588.8 CCH58461.1 - 1.4e-05 24.7 0.5 2.5e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4591 PF15261.1 CCH58461.1 - 5.9 7.1 7.5 0.52 10.5 0.3 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4591) Peptidase_S8 PF00082.17 CCH58462.1 - 2.9e-41 141.4 0.8 4.1e-41 140.9 0.6 1.1 1 0 0 1 1 1 1 Subtilase family Dus PF01207.12 CCH58463.1 - 4e-60 203.2 0.0 8.5e-60 202.1 0.0 1.4 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 CCH58463.1 - 0.055 12.3 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase TMP-TENI PF02581.12 CCH58463.1 - 0.064 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI PRK PF00485.13 CCH58464.1 - 2.8e-59 199.9 0.0 4.9e-59 199.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CCH58464.1 - 4.7e-32 110.8 0.2 7.1e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 CCH58464.1 - 3.9e-09 37.3 0.0 1.1e-08 35.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH58464.1 - 1.5e-07 31.7 0.0 1.8e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCH58464.1 - 0.0024 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 CCH58464.1 - 0.0099 15.5 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 CCH58464.1 - 0.0099 15.7 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCH58464.1 - 0.079 12.5 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain HA2 PF04408.18 CCH58465.1 - 9.7e-19 67.2 0.1 5.6e-18 64.8 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCH58465.1 - 1.5e-14 53.7 0.0 4.3e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCH58465.1 - 9.2e-14 51.0 0.0 2.3e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH58465.1 - 2.4e-06 27.1 0.1 7.3e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH58465.1 - 3.9e-05 23.7 0.5 0.00048 20.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 CCH58465.1 - 0.0007 18.5 0.0 0.0015 17.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 CCH58465.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_19 PF13245.1 CCH58465.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CCH58465.1 - 0.16 11.5 0.0 0.46 10.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCH58465.1 - 0.42 10.8 0.0 0.42 10.8 0.0 3.2 3 1 0 3 3 3 0 ABC transporter Glyoxalase PF00903.20 CCH58466.1 - 3.1e-31 108.0 0.0 1.4e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCH58466.1 - 3e-25 88.8 0.0 5.7e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCH58466.1 - 5.3e-10 39.2 0.0 0.00015 21.7 0.0 3.6 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 CCH58466.1 - 0.001 18.7 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Band_7_1 PF13421.1 CCH58466.1 - 0.075 12.5 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 SPFH domain-Band 7 family DUF4033 PF13225.1 CCH58466.1 - 0.099 12.2 0.2 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4033) Glyoxalase_3 PF13468.1 CCH58466.1 - 0.17 11.7 0.0 15 5.4 0.0 3.2 1 1 0 2 2 2 0 Glyoxalase-like domain Inp1 PF12634.2 CCH58467.1 - 2.2e-37 127.9 0.7 2.2e-37 127.9 0.5 2.4 2 1 0 2 2 2 1 Inheritance of peroxisomes protein 1 ERG2_Sigma1R PF04622.7 CCH58468.1 - 1.5e-90 302.2 0.7 1.7e-90 302.0 0.5 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein MRP-S26 PF14943.1 CCH58470.1 - 0.21 11.1 13.1 0.54 9.8 1.1 2.3 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 LSM PF01423.17 CCH58471.1 - 9.3e-14 50.7 0.8 1.3e-13 50.2 0.6 1.2 1 0 0 1 1 1 1 LSM domain TRAPPC9-Trs120 PF08626.6 CCH58472.1 - 9.8e-278 924.1 34.7 2.6e-152 508.6 17.6 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 CCH58472.1 - 0.015 15.2 0.2 0.041 13.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCH58472.1 - 0.13 11.8 0.0 0.49 10.0 0.0 2.0 1 0 0 1 1 1 0 TPR repeat PINIT PF14324.1 CCH58473.1 - 9.4e-38 129.5 2.5 9.4e-38 129.5 1.7 3.0 3 0 0 3 3 3 1 PINIT domain zf-MIZ PF02891.15 CCH58473.1 - 3.9e-21 74.2 6.4 7.1e-21 73.4 4.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 CCH58473.1 - 5.7e-10 38.4 0.6 1.1e-09 37.6 0.4 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 CCH58473.1 - 0.00044 19.7 0.7 0.0011 18.4 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCH58473.1 - 0.014 15.1 0.1 0.054 13.2 0.1 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CCH58473.1 - 0.057 13.0 0.9 0.1 12.3 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH58473.1 - 0.061 13.3 2.8 0.13 12.3 2.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH58473.1 - 0.33 10.6 1.6 0.72 9.5 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH58473.1 - 1 9.2 3.4 2.3 8.1 2.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ICMT PF04140.9 CCH58474.1 - 5.8e-28 96.9 0.9 1.1e-27 96.0 0.6 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCH58474.1 - 1.2e-14 54.2 3.7 2.9e-14 53.0 2.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 CCH58474.1 - 7.9e-06 25.3 0.3 9.5e-06 25.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 CCH58474.1 - 0.0015 17.9 0.4 0.0026 17.1 0.3 1.4 1 0 0 1 1 1 1 NnrU protein zf-HIT PF04438.11 CCH58475.1 - 0.00016 21.2 8.9 0.0013 18.3 6.0 2.2 2 0 0 2 2 2 1 HIT zinc finger zf-B_box PF00643.19 CCH58475.1 - 1.3 8.9 8.2 2.3 8.2 5.7 1.3 1 0 0 1 1 1 0 B-box zinc finger DUF2358 PF10184.4 CCH58475.1 - 1.4 8.8 4.3 0.64 9.9 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2358) ABC_tran PF00005.22 CCH58476.1 - 1.2e-40 138.9 0.2 1e-23 84.1 0.0 3.6 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCH58476.1 - 1.1e-36 126.6 28.9 2.2e-31 109.2 15.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CCH58476.1 - 5.5e-09 35.5 8.6 0.011 14.9 0.5 4.6 3 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH58476.1 - 1.3e-07 30.9 0.1 0.0045 16.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCH58476.1 - 8.6e-06 26.5 0.8 0.15 12.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CCH58476.1 - 1.7e-05 24.9 1.4 1.3 9.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 CCH58476.1 - 2.2e-05 23.5 0.0 0.018 13.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 CCH58476.1 - 2.4e-05 23.5 0.1 0.23 10.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCH58476.1 - 0.00017 21.9 20.0 0.091 13.0 0.1 3.9 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CCH58476.1 - 0.00028 21.1 1.5 1.3 9.3 0.1 3.5 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CCH58476.1 - 0.00089 19.1 0.0 0.058 13.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCH58476.1 - 0.00095 19.2 0.1 0.48 10.3 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.1 CCH58476.1 - 0.002 17.5 0.4 0.48 9.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 CCH58476.1 - 0.0023 18.4 0.1 3.8 8.0 0.0 3.3 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 CCH58476.1 - 0.0024 17.7 0.5 2 8.2 0.1 3.4 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.1 CCH58476.1 - 0.005 16.4 0.2 3.5 7.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 CCH58476.1 - 0.0066 16.0 0.1 9.9 5.6 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 CCH58476.1 - 0.0081 16.3 0.3 14 5.9 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_10 PF12846.2 CCH58476.1 - 0.018 14.4 0.2 0.14 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 CCH58476.1 - 0.02 14.3 0.6 0.58 9.5 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_11 PF13086.1 CCH58476.1 - 0.024 14.2 0.2 1.5 8.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCH58476.1 - 0.028 14.1 2.3 1.4 8.5 0.1 3.2 3 0 0 3 3 3 0 NTPase APS_kinase PF01583.15 CCH58476.1 - 0.048 13.3 0.6 24 4.5 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase Zeta_toxin PF06414.7 CCH58476.1 - 0.048 12.7 0.1 3.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 CCH58476.1 - 0.054 13.2 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain ATP-synt_ab PF00006.20 CCH58476.1 - 0.059 12.8 0.1 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 CCH58476.1 - 0.088 12.2 3.0 2.2 7.7 0.2 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CCH58476.1 - 0.12 12.3 0.3 0.88 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCH58476.1 - 0.18 12.0 1.7 0.97 9.6 0.2 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH58476.1 - 0.36 10.5 1.6 21 4.8 0.1 3.4 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Carn_acyltransf PF00755.15 CCH58478.1 - 8.3e-142 473.2 0.0 1e-141 472.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1454 PF07305.7 CCH58479.1 - 0.043 12.8 0.3 0.09 11.8 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1454) DER1 PF04511.10 CCH58481.1 - 5.2e-22 78.3 0.4 6.4e-22 78.0 0.3 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_L2_C PF03947.13 CCH58482.1 - 2.8e-48 162.9 0.3 5e-48 162.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCH58482.1 - 4.9e-27 93.7 0.3 1.4e-26 92.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.12 CCH58483.1 - 2.9e-24 85.7 0.0 4.6e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCH58483.1 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3899 PF13038.1 CCH58483.1 - 0.028 14.5 0.2 0.064 13.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) AAA_12 PF13087.1 CCH58483.1 - 0.11 11.7 3.7 10 5.4 1.4 2.9 2 1 0 2 2 2 0 AAA domain Peptidase_S49_N PF08496.5 CCH58483.1 - 0.18 11.5 2.4 0.45 10.3 1.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0542 PF15086.1 CCH58483.1 - 0.33 10.7 5.9 0.88 9.3 4.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 EMP24_GP25L PF01105.19 CCH58484.1 - 3.9e-42 144.0 0.0 4.6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD M16C_assoc PF08367.6 CCH58485.1 - 1.4e-68 230.4 4.1 2.7e-68 229.5 2.9 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CCH58485.1 - 6.5e-29 100.9 0.2 6.1e-17 61.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCH58485.1 - 4.3e-11 42.7 0.0 6.2e-10 39.0 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2192 PF09958.4 CCH58485.1 - 0.0053 16.0 0.8 0.016 14.4 0.5 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2192) UBA_4 PF14555.1 CCH58486.1 - 2e-11 43.2 0.0 4.6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 CCH58486.1 - 1.1e-06 28.6 0.1 0.00037 20.5 0.0 3.2 2 1 0 2 2 2 2 UBX domain Methyltransf_11 PF08241.7 CCH58487.1 - 9.6e-13 48.4 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH58487.1 - 1.2e-08 34.8 0.1 1.1e-07 31.7 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH58487.1 - 9.7e-07 29.1 0.1 9.7e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH58487.1 - 1.8e-06 27.6 0.1 2.9e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH58487.1 - 0.00015 22.0 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH58487.1 - 0.00018 22.0 0.4 0.0005 20.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH58487.1 - 0.0064 15.6 0.0 0.043 12.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF1682 PF07946.9 CCH58487.1 - 0.061 12.1 10.8 0.11 11.3 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Herpes_UL95 PF03038.9 CCH58487.1 - 0.29 9.9 2.6 0.42 9.4 1.8 1.2 1 0 0 1 1 1 0 UL95 family NARP1 PF12569.3 CCH58487.1 - 0.68 8.6 9.4 0.96 8.1 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PIG-S PF10510.4 CCH58488.1 - 7.9e-35 120.5 2.6 1.3e-34 119.7 1.8 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Metallophos PF00149.23 CCH58489.1 - 4.7e-39 133.8 0.2 4.7e-39 133.8 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PIG-P PF08510.7 CCH58490.1 - 3.6e-23 81.5 1.5 4.6e-23 81.2 1.0 1.1 1 0 0 1 1 1 1 PIG-P Zn_clus PF00172.13 CCH58492.1 - 1.6e-06 27.8 12.4 1.6e-06 27.8 8.6 2.7 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3666 PF12408.3 CCH58492.1 - 0.065 12.3 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase PI-PLC-X PF00388.14 CCH58493.1 - 7.2e-46 155.2 0.4 1.9e-45 153.8 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CCH58493.1 - 9e-37 125.6 0.2 9e-37 125.6 0.2 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CCH58493.1 - 9.3e-08 31.8 0.1 3.3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 CCH58493.1 - 0.00058 19.8 1.1 0.005 16.8 0.7 2.7 1 1 1 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CCH58493.1 - 0.00075 18.6 0.4 0.0037 16.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CCH58493.1 - 0.00094 19.2 1.5 0.0034 17.4 1.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 CCH58493.1 - 0.012 15.2 0.3 0.034 13.8 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 CCH58493.1 - 0.051 12.9 0.0 0.16 11.3 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CCH58493.1 - 0.1 12.5 1.4 0.36 10.8 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain Ank_2 PF12796.2 CCH58494.1 - 2.4e-11 43.7 0.1 1.5e-07 31.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCH58494.1 - 3.1e-10 39.3 0.1 0.00032 20.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CCH58494.1 - 3.4e-10 39.1 1.0 0.00035 20.5 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CCH58494.1 - 7e-08 32.4 0.7 0.00087 19.4 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCH58494.1 - 2e-06 28.1 0.4 0.0023 18.4 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) MAT_Alpha1 PF04769.7 CCH58495.1 - 2.7e-07 30.1 1.1 2.7e-07 30.1 0.8 2.3 2 1 1 3 3 3 1 Mating-type protein MAT alpha 1 Homez PF11569.3 CCH58496.1 - 9.2e-08 31.0 0.2 2.3e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 CCH58496.1 - 2.2e-07 30.3 0.5 2.2e-07 30.3 0.4 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CCH58496.1 - 1.4e-05 24.6 2.8 1.9e-05 24.2 0.8 2.2 2 0 0 2 2 2 1 Homeobox KN domain DUF4378 PF14309.1 CCH58496.1 - 0.85 9.6 4.8 2.4 8.1 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4378) Choline_kinase PF01633.15 CCH58496.1 - 2.8 7.4 9.5 0.13 11.7 0.2 2.6 2 1 0 2 2 2 0 Choline/ethanolamine kinase AA_permease PF00324.16 CCH58497.1 - 1.9e-120 402.4 46.0 2.2e-120 402.2 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH58497.1 - 3.4e-25 88.4 49.1 4.4e-25 88.0 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease RrnaAD PF00398.15 CCH58499.1 - 2.9e-63 213.3 0.0 3.5e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCH58499.1 - 3.2e-10 40.0 0.0 4.6e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH58499.1 - 5.3e-06 26.9 0.0 1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCH58499.1 - 5.4e-05 22.8 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 CCH58499.1 - 0.0011 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 CCH58499.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH58499.1 - 0.0026 17.3 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH58499.1 - 0.0035 16.7 0.0 0.0065 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCH58499.1 - 0.007 16.8 0.0 0.025 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CCH58499.1 - 0.008 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CCH58499.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.11 CCH58499.1 - 0.02 13.8 0.2 0.3 9.9 0.0 2.1 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_2 PF00891.13 CCH58499.1 - 0.025 13.7 0.0 0.053 12.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_25 PF13649.1 CCH58499.1 - 0.038 14.3 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain KAR9 PF08580.5 CCH58501.1 - 2.1e-77 260.9 56.2 4.8e-77 259.8 38.8 1.9 1 1 0 1 1 1 1 Yeast cortical protein KAR9 CAF1C_H4-bd PF12265.3 CCH58502.1 - 2.1e-26 91.6 0.7 6.3e-26 90.0 0.5 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CCH58502.1 - 1.6e-19 68.9 0.2 2.2e-06 27.3 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Lyase_1 PF00206.15 CCH58503.1 - 6.7e-111 370.4 0.2 8.1e-111 370.1 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCH58503.1 - 2.7e-23 81.7 0.0 9.6e-23 80.0 0.0 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus Calpain_inhib PF00748.14 CCH58503.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Calpain inhibitor Rad60-SLD PF11976.3 CCH58504.1 - 5.1e-22 77.3 0.1 6.4e-22 77.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCH58504.1 - 1.1e-11 43.9 0.0 1.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 CCH58505.1 - 1.5e-74 250.4 0.0 5.1e-74 248.6 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58505.1 - 5.2e-36 124.0 0.0 1.3e-35 122.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58505.1 - 2.1e-05 23.6 0.0 4.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH58505.1 - 0.24 11.0 0.0 0.45 10.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cyclin PF08613.6 CCH58506.1 - 1.9e-33 115.9 1.2 3e-33 115.3 0.9 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCH58506.1 - 0.0004 19.9 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.15 CCH58507.1 - 3.9e-48 163.2 1.0 7.8e-48 162.2 0.7 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CCH58507.1 - 3.9e-22 78.3 4.0 2.7e-20 72.4 0.1 2.7 2 0 0 2 2 2 2 PMC2NT (NUC016) domain HRDC PF00570.18 CCH58507.1 - 3.2e-12 45.9 0.0 7.1e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Ras PF00071.17 CCH58508.1 - 1.9e-55 186.6 0.2 2.3e-55 186.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH58508.1 - 1.4e-19 70.7 0.0 2.7e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH58508.1 - 3.4e-16 58.9 0.0 4.3e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCH58508.1 - 3e-08 33.1 0.1 3.6e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH58508.1 - 5.8e-08 32.3 0.1 2.3e-06 27.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCH58508.1 - 2.1e-06 27.0 0.1 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCH58508.1 - 8.6e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCH58508.1 - 2.7e-05 24.3 0.0 7.2e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH58508.1 - 0.00016 21.7 0.1 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 CCH58508.1 - 0.00033 20.2 0.2 0.012 15.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 CCH58508.1 - 0.0032 17.1 0.2 0.046 13.4 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 CCH58508.1 - 0.0039 16.8 0.2 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCH58508.1 - 0.0043 16.5 0.6 0.068 12.6 0.4 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CCH58508.1 - 0.0069 15.5 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 CCH58508.1 - 0.0098 15.3 0.1 0.048 13.1 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CCH58508.1 - 0.016 14.9 0.1 0.024 14.3 0.1 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CCH58508.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 CCH58508.1 - 0.04 13.6 0.0 0.078 12.6 0.0 1.5 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 CCH58508.1 - 0.083 12.3 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.1 CCH58508.1 - 0.091 11.3 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 CCH58508.1 - 0.092 11.7 0.1 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 CCH58508.1 - 0.15 12.3 0.3 0.25 11.6 0.2 1.7 1 1 0 1 1 1 0 ABC transporter ABC_membrane PF00664.18 CCH58509.1 - 1.1e-51 175.8 5.9 1.5e-51 175.4 4.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCH58509.1 - 4.2e-33 114.5 0.0 9.2e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCH58509.1 - 0.00017 20.9 0.0 0.00031 20.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCH58509.1 - 0.00076 19.5 1.3 2 8.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCH58509.1 - 0.0039 17.3 0.0 0.083 13.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH58509.1 - 0.0062 17.3 0.0 0.014 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH58509.1 - 0.0084 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CCH58509.1 - 0.013 14.9 0.0 0.045 13.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CCH58509.1 - 0.016 14.3 0.0 0.043 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCH58509.1 - 0.021 14.3 0.1 0.72 9.2 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 CCH58509.1 - 0.023 14.1 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCH58509.1 - 0.036 14.2 0.0 0.37 10.9 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH58509.1 - 0.044 13.5 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CCH58509.1 - 0.084 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 CCH58509.1 - 0.088 12.2 0.1 1.4 8.3 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein ATP-synt_Eps PF04627.8 CCH58510.1 - 1e-21 76.2 1.4 1.1e-21 76.0 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_phi PF04931.8 CCH58511.1 - 7.9e-97 324.8 56.1 7.6e-95 318.3 38.9 2.2 1 1 0 1 1 1 1 DNA polymerase phi Kinesin PF00225.18 CCH58513.1 - 2.7e-92 309.0 40.1 4e-61 206.5 8.3 3.7 3 1 0 3 3 3 2 Kinesin motor domain DUF367 PF04034.8 CCH58514.1 - 1e-50 170.5 0.0 1.7e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CCH58514.1 - 7.1e-15 54.2 0.1 1.2e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RHS_repeat PF05593.9 CCH58514.1 - 0.0055 16.8 0.0 0.063 13.4 0.0 2.6 2 1 1 3 3 3 2 RHS Repeat Ank_5 PF13857.1 CCH58515.1 - 2.8e-07 30.5 0.2 0.19 12.0 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) VPS9 PF02204.13 CCH58515.1 - 6.9e-07 29.2 0.8 4e-06 26.7 0.5 2.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_3 PF13606.1 CCH58515.1 - 0.16 12.2 4.6 67 4.1 0.0 5.4 6 0 0 6 6 6 0 Ankyrin repeat TPR_11 PF13414.1 CCH58516.1 - 5.5e-22 77.1 6.3 6.4e-17 60.9 0.1 3.3 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 CCH58516.1 - 1e-12 46.8 3.0 0.0015 18.3 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCH58516.1 - 1.3e-10 40.3 11.3 0.00024 20.5 0.5 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCH58516.1 - 9.6e-08 31.8 2.5 5e-05 23.1 0.6 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH58516.1 - 4e-07 29.7 7.5 0.0053 16.8 0.3 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH58516.1 - 6.5e-06 26.6 0.0 0.002 18.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCH58516.1 - 1.6e-05 24.3 0.9 0.98 9.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCH58516.1 - 0.00012 22.3 0.1 0.2 12.0 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCH58516.1 - 0.00013 21.5 11.6 0.12 12.1 1.0 4.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCH58516.1 - 0.00073 19.8 1.4 0.74 10.4 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCH58516.1 - 0.00076 19.9 0.0 1.3 9.8 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 CCH58516.1 - 0.009 15.8 0.5 1 9.3 0.0 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 CCH58516.1 - 0.17 11.7 0.0 0.64 9.9 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat GATA PF00320.22 CCH58517.1 - 1.2e-11 43.7 4.9 2.1e-11 42.9 3.4 1.4 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 CCH58517.1 - 0.065 13.0 1.4 0.26 11.1 1.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon RRN7 PF11781.3 CCH58517.1 - 0.34 10.4 1.7 8.5 5.9 0.6 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Fcf1 PF04900.7 CCH58518.1 - 3.8e-30 103.9 0.2 3.8e-30 103.9 0.1 1.9 2 0 0 2 2 2 1 Fcf1 Peptidase_S8 PF00082.17 CCH58519.1 - 5.5e-54 183.2 5.9 7.9e-54 182.7 4.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCH58519.1 - 6.5e-10 39.4 0.0 6.5e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 RXT2_N PF08595.6 CCH58519.1 - 0.0085 15.9 1.5 0.016 15.0 1.1 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal TPR_11 PF13414.1 CCH58520.1 - 0.00038 20.0 0.2 0.0028 17.2 0.1 2.3 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 CCH58520.1 - 0.014 16.0 0.2 0.047 14.3 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM101 PF15068.1 CCH58520.1 - 0.1 12.0 2.1 0.16 11.4 1.5 1.2 1 0 0 1 1 1 0 FAM101 family TPR_21 PF09976.4 CCH58520.1 - 0.88 9.5 9.3 5.6 6.9 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 CCH58520.1 - 4 7.6 5.3 0.74 9.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CAP_GLY PF01302.20 CCH58521.1 - 6.3e-15 54.6 0.0 1.1e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain UBN2 PF14223.1 CCH58521.1 - 0.0014 18.3 1.0 0.0014 18.3 0.7 1.7 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type Tropomyosin_1 PF12718.2 CCH58521.1 - 0.0032 17.3 4.6 0.0032 17.3 3.2 2.2 1 1 1 2 2 2 1 Tropomyosin like Reo_sigmaC PF04582.7 CCH58521.1 - 0.0048 16.1 1.9 0.0071 15.5 1.3 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 CCH58521.1 - 0.008 14.6 12.3 0.01 14.3 8.5 1.0 1 0 0 1 1 1 1 AAA domain ATG16 PF08614.6 CCH58521.1 - 0.008 16.0 4.8 0.008 16.0 3.3 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 CCH58521.1 - 0.0098 13.6 15.8 0.015 13.1 11.0 1.1 1 0 0 1 1 1 1 Myosin tail DUF641 PF04859.7 CCH58521.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) zf-CCHC_2 PF13696.1 CCH58521.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Zinc knuckle Allexi_40kDa PF05549.6 CCH58521.1 - 0.053 12.8 12.9 0.062 12.5 8.5 1.3 1 1 0 1 1 1 0 Allexivirus 40kDa protein Macoilin PF09726.4 CCH58521.1 - 0.064 11.5 10.9 0.093 11.0 7.6 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-CCHC PF00098.18 CCH58521.1 - 0.066 13.1 1.2 0.11 12.4 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4201 PF13870.1 CCH58521.1 - 0.083 12.3 15.0 0.15 11.5 10.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) APG6 PF04111.7 CCH58521.1 - 0.33 9.9 19.9 0.46 9.4 13.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Muted PF14942.1 CCH58521.1 - 0.49 10.2 12.6 0.56 10.0 8.3 1.3 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein MRP-S26 PF14943.1 CCH58521.1 - 0.53 9.8 11.6 0.77 9.2 8.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Viral_P18 PF04521.8 CCH58521.1 - 0.58 9.6 6.6 0.15 11.5 1.9 1.9 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CCDC155 PF14662.1 CCH58521.1 - 0.91 9.0 20.1 12 5.4 13.9 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF3987 PF13148.1 CCH58521.1 - 4 5.9 11.4 5.2 5.5 7.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) RA PF00788.18 CCH58522.1 - 2.9e-16 59.7 0.1 4.9e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ste50p-SAM PF09235.5 CCH58522.1 - 5.9e-10 39.0 4.2 2.2e-09 37.1 2.9 2.0 1 1 0 1 1 1 1 Ste50p, sterile alpha motif SAM_2 PF07647.12 CCH58522.1 - 0.006 16.4 0.8 0.18 11.6 0.1 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF3128 PF11326.3 CCH58523.1 - 1.2e-22 79.7 1.1 1.4e-22 79.6 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) UPF0203 PF05254.7 CCH58523.1 - 0.012 15.4 2.2 0.063 13.1 1.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) CHCH PF06747.8 CCH58523.1 - 0.1 12.5 0.8 0.36 10.7 0.6 1.9 1 1 0 1 1 1 0 CHCH domain SelR PF01641.13 CCH58524.1 - 7.8e-45 151.5 0.0 9.2e-45 151.3 0.0 1.0 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.7 CCH58524.1 - 0.0072 15.6 0.8 2.4 7.5 0.1 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding GFA PF04828.9 CCH58524.1 - 0.0089 15.9 0.1 0.58 10.1 0.0 2.3 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 CCH58524.1 - 0.032 14.0 2.6 0.42 10.4 0.4 2.2 1 1 1 2 2 2 0 Double zinc ribbon GAT PF03127.9 CCH58525.1 - 2.1e-08 34.0 0.1 5.6e-08 32.6 0.1 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 CCH58525.1 - 6.8e-06 25.7 1.3 1.9e-05 24.3 0.2 2.2 2 1 1 3 3 3 1 VHS domain DUF2408 PF10303.4 CCH58525.1 - 0.012 15.6 5.2 0.014 15.5 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) PTS_IIA PF02255.11 CCH58525.1 - 0.078 12.8 0.1 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF4463 PF14703.1 CCH58525.1 - 0.73 10.3 3.5 14 6.2 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) V-SNARE PF05008.10 CCH58527.1 - 0.59 10.3 8.0 1 9.5 1.4 2.7 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FtsH_ext PF06480.10 CCH58527.1 - 0.62 10.2 4.1 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 FtsH Extracellular WD40 PF00400.27 CCH58528.1 - 9.3e-22 76.0 0.9 0.00024 20.8 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PIG-X PF08320.7 CCH58529.1 - 1.1e-37 129.3 0.3 1.8e-37 128.6 0.2 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 UCR_14kD PF02271.11 CCH58531.1 - 1.1e-40 137.6 0.8 1.3e-40 137.4 0.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Fumble PF03630.9 CCH58532.1 - 3.2e-115 384.6 5.9 2.2e-112 375.2 1.9 2.0 1 1 1 2 2 2 2 Fumble DUF512 PF04459.7 CCH58532.1 - 0.023 13.7 0.0 0.062 12.3 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF512) DUF3666 PF12408.3 CCH58532.1 - 0.029 13.4 1.5 0.082 12.0 0.2 2.2 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase DUF948 PF06103.6 CCH58533.1 - 0.22 11.4 3.9 0.47 10.3 1.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RPAP1_C PF08620.5 CCH58534.1 - 4e-30 103.4 0.1 8.7e-30 102.3 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CCH58534.1 - 1.4e-14 53.3 8.2 3.3e-14 52.1 3.8 2.8 3 0 0 3 3 3 1 RPAP1-like, N-terminal HEAT PF02985.17 CCH58534.1 - 0.046 13.7 0.0 0.25 11.5 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat ArfGap PF01412.13 CCH58535.1 - 4.2e-29 100.6 3.3 4.2e-29 100.6 2.3 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 CCH58535.1 - 4.5e-07 30.0 0.3 4.5e-07 30.0 0.2 3.7 4 0 0 4 4 4 1 PH domain Pkinase PF00069.20 CCH58536.1 - 2.2e-66 223.6 0.0 3e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58536.1 - 5.3e-48 163.3 0.0 7.5e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58536.1 - 2.6e-06 26.6 0.0 8.2e-06 24.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF3827 PF12877.2 CCH58536.1 - 0.011 13.9 0.4 0.016 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF4196 PF13846.1 CCH58537.1 - 0.019 15.2 10.0 0.044 14.0 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) DUF2201_N PF13203.1 CCH58537.1 - 8.4 5.4 6.0 12 4.9 4.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Zn_clus PF00172.13 CCH58538.1 - 0.0004 20.2 6.0 0.00073 19.3 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTP_transf_2 PF01467.21 CCH58539.1 - 2.6e-09 37.3 0.1 4.9e-09 36.4 0.1 1.5 1 1 0 1 1 1 1 Cytidylyltransferase DUF1620 PF07774.8 CCH58540.1 - 8.4e-70 234.4 0.0 1.8e-69 233.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CCH58540.1 - 0.0067 15.9 0.0 3.5 7.0 0.0 2.8 3 0 0 3 3 3 2 PQQ-like domain DUF179 PF02622.10 CCH58540.1 - 0.026 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 Mgr1 PF08602.5 CCH58541.1 - 1.2e-131 439.0 4.1 1.5e-131 438.7 2.9 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit GrpE PF01025.14 CCH58541.1 - 0.015 14.8 3.3 0.03 13.8 2.3 1.4 1 0 0 1 1 1 0 GrpE DUF1700 PF08006.6 CCH58541.1 - 1.2 8.4 4.9 0.21 10.8 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Thioredoxin PF00085.15 CCH58542.1 - 8.6e-28 96.0 0.9 1.6e-16 59.8 0.1 4.2 4 1 1 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.1 CCH58542.1 - 1.1e-16 61.1 9.5 5.2e-15 55.7 0.7 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain ERp29_N PF07912.8 CCH58542.1 - 0.00031 20.6 0.6 0.0025 17.7 0.0 2.6 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_8 PF13905.1 CCH58542.1 - 0.02 14.9 2.2 0.72 10.0 0.1 3.8 3 1 0 3 3 3 0 Thioredoxin-like Thioredoxin_2 PF13098.1 CCH58542.1 - 0.022 14.9 0.8 0.51 10.5 0.1 3.0 2 1 0 2 2 2 0 Thioredoxin-like domain GRASP55_65 PF04495.9 CCH58543.1 - 3.7e-31 107.9 0.0 5.7e-30 104.1 0.0 2.1 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.11 CCH58544.1 - 1.6e-81 273.1 0.0 2.1e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCH58544.1 - 1.7e-60 203.8 0.0 2.5e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Spb1_C PF07780.7 CCH58545.1 - 1.7e-75 253.2 27.7 1.7e-75 253.2 19.2 3.6 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 CCH58545.1 - 3.3e-53 180.3 0.0 8.6e-53 179.0 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CCH58545.1 - 4.8e-53 178.9 21.6 4.8e-53 178.9 15.0 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) Peptidase_M3 PF01432.15 CCH58546.1 - 4.3e-144 480.9 2.9 7.7e-144 480.1 2.0 1.4 1 0 0 1 1 1 1 Peptidase family M3 FlgM PF04316.8 CCH58546.1 - 0.034 14.0 0.5 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM MRC1 PF09444.5 CCH58547.1 - 1.7e-44 151.6 13.6 1.7e-44 151.6 9.4 7.9 5 3 1 7 7 7 1 MRC1-like domain MAT_Alpha1 PF04769.7 CCH58549.1 - 2.7e-07 30.1 1.1 2.7e-07 30.1 0.8 2.3 2 1 1 3 3 3 1 Mating-type protein MAT alpha 1 Homez PF11569.3 CCH58550.1 - 8.5e-08 31.1 0.2 2.3e-07 29.7 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox PF00046.24 CCH58550.1 - 2.7e-07 30.0 3.7 3e-07 29.9 0.3 2.3 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CCH58550.1 - 9e-06 25.2 2.5 1.6e-05 24.4 0.8 2.1 2 0 0 2 2 2 1 Homeobox KN domain Choline_kinase PF01633.15 CCH58550.1 - 0.11 12.0 0.3 0.11 12.0 0.2 2.0 2 1 1 3 3 3 0 Choline/ethanolamine kinase DUF4378 PF14309.1 CCH58550.1 - 0.31 11.0 3.1 2 8.4 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4378) Peroxin-13_N PF04088.8 CCH58551.1 - 2.2e-56 190.2 2.7 3.4e-56 189.5 1.9 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 CCH58551.1 - 8.2e-08 31.7 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCH58551.1 - 2.3e-07 30.0 0.0 4.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCH58551.1 - 6.7e-06 25.4 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CCH58551.1 - 2.4e-05 24.4 0.2 4.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain MMR1 PF08505.5 CCH58552.1 - 1.5e-14 54.6 31.7 2.3e-12 47.4 1.6 4.3 2 2 1 4 4 4 2 Mitochondrial Myo2 receptor-related protein LURAP PF14854.1 CCH58552.1 - 0.00037 20.1 0.8 0.00037 20.1 0.6 2.1 2 0 0 2 2 2 1 Leucine rich adaptor protein bZIP_1 PF00170.16 CCH58552.1 - 0.0095 15.8 0.4 0.0095 15.8 0.3 3.2 3 0 0 3 3 3 1 bZIP transcription factor DUF1192 PF06698.6 CCH58552.1 - 0.077 12.8 0.2 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.6 CCH58552.1 - 1.7 8.5 9.8 0.11 12.4 0.9 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 CCH58552.1 - 4.2 7.8 7.1 12 6.4 1.5 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec61_beta PF03911.11 CCH58553.1 - 1.7e-16 59.7 0.6 2.2e-16 59.3 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family DUF1151 PF06625.6 CCH58553.1 - 0.04 13.6 0.9 0.046 13.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) CWC25 PF12542.3 CCH58553.1 - 0.052 14.0 0.4 0.069 13.5 0.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor MscS_TM PF12794.2 CCH58553.1 - 0.063 11.8 0.1 0.075 11.6 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF2897 PF11446.3 CCH58553.1 - 7.5 6.4 6.9 0.94 9.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) RRM_1 PF00076.17 CCH58554.1 - 5.3e-08 32.3 0.1 2e-07 30.5 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58554.1 - 7.4e-08 32.2 0.1 1.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58554.1 - 0.0001 22.0 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.1 CCH58555.1 - 7.8e-10 38.7 0.6 1.1e-08 35.0 0.1 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCH58555.1 - 4.9e-05 23.2 1.6 0.00037 20.4 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Chorismate_bind PF00425.13 CCH58556.1 - 5.2e-86 288.1 0.0 7.8e-86 287.5 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CCH58556.1 - 2.3e-30 105.4 0.0 4.3e-28 98.0 0.0 3.0 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.13 CCH58556.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF466 PF04328.8 CCH58556.1 - 0.18 11.6 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF466) PTH2 PF01981.11 CCH58557.1 - 9.7e-45 150.9 0.0 1.5e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BSP_II PF05432.6 CCH58557.1 - 0.0066 15.7 0.8 0.0096 15.2 0.6 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 CCH58557.1 - 0.091 11.9 0.4 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region IF4E PF01652.13 CCH58558.1 - 6.3e-56 188.4 2.2 7.7e-56 188.1 1.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SBP_bac_1 PF01547.20 CCH58558.1 - 0.058 13.1 1.3 0.08 12.6 0.2 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Abhydrolase_5 PF12695.2 CCH58559.1 - 5.8e-21 74.7 0.0 7.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH58559.1 - 1.2e-15 58.0 0.0 1.1e-13 51.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH58559.1 - 1.9e-12 47.2 0.0 3.7e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCH58559.1 - 5e-06 25.9 0.0 1.8e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CCH58559.1 - 2.7e-05 23.7 0.0 0.016 14.6 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CCH58559.1 - 4.3e-05 23.3 0.0 0.0025 17.5 0.0 2.2 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.7 CCH58559.1 - 0.0019 16.8 0.0 0.0032 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 DUF1749 PF08538.5 CCH58559.1 - 0.0024 16.8 0.0 0.0058 15.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) FSH1 PF03959.8 CCH58559.1 - 0.004 16.6 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 CCH58559.1 - 0.0058 16.0 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase UPF0227 PF05728.7 CCH58559.1 - 0.02 14.6 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.3 CCH58559.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 CCH58559.1 - 0.05 12.8 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family AXE1 PF05448.7 CCH58559.1 - 0.065 11.7 0.0 0.78 8.1 0.0 2.2 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2305 PF10230.4 CCH58559.1 - 0.082 12.3 0.0 5.2 6.4 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 CCH58559.1 - 0.084 12.4 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Sugar_tr PF00083.19 CCH58560.1 - 2e-112 376.0 35.1 2.3e-112 375.8 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58560.1 - 6.8e-25 87.5 38.4 1.2e-19 70.3 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-DNL PF05180.7 CCH58562.1 - 2.7e-30 103.8 1.6 4.5e-30 103.1 1.1 1.4 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.1 CCH58562.1 - 0.0057 16.3 1.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CCH58562.1 - 0.0069 15.9 0.9 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 zinc-ribbon domain Elf1 PF05129.8 CCH58562.1 - 0.011 15.4 0.6 0.019 14.6 0.4 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like HypA PF01155.14 CCH58562.1 - 0.023 14.3 0.1 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family UPF0167 PF03691.9 CCH58562.1 - 0.093 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-CSL PF05207.8 CCH58562.1 - 0.11 11.9 0.2 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger Zn-ribbon_8 PF09723.5 CCH58562.1 - 0.16 11.9 2.7 0.38 10.7 1.8 1.6 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CCH58562.1 - 0.23 11.2 4.9 3.5 7.5 0.4 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 CCH58562.1 - 0.96 9.1 5.6 13 5.5 4.3 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) Glyco_hydro_72 PF03198.9 CCH58563.1 - 9.2e-131 435.5 0.7 1.3e-130 435.0 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 CCH58563.1 - 0.0075 15.5 0.4 1.7 7.8 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) tRNA_anti-codon PF01336.20 CCH58564.1 - 5.1e-12 45.4 0.6 9.5e-12 44.6 0.4 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 CCH58564.1 - 6.8e-07 29.6 1.2 1.8e-06 28.2 0.1 2.3 2 1 0 2 2 2 1 Replication protein A C terminal Rrf2 PF02082.15 CCH58564.1 - 0.055 13.5 0.1 0.36 10.9 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator tRNA_anti_2 PF13742.1 CCH58564.1 - 0.085 12.7 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF329 PF03884.9 CCH58564.1 - 0.1 12.1 1.1 3.3 7.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) HTH_24 PF13412.1 CCH58564.1 - 0.1 11.9 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DEP PF00610.16 CCH58564.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.8 1 1 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TEX19 PF15553.1 CCH58564.1 - 0.11 12.3 1.0 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Testis-expressed protein 19 PCI PF01399.22 CCH58564.1 - 0.12 12.6 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 PCI domain Kri1_C PF12936.2 CCH58565.1 - 5.1e-29 100.0 6.8 5.1e-29 100.0 4.7 5.8 5 2 2 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.7 CCH58565.1 - 4e-09 36.6 29.0 4e-09 36.6 20.1 7.0 3 2 2 5 5 5 1 KRI1-like family Pkinase PF00069.20 CCH58566.1 - 1e-58 198.5 0.0 1.4e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58566.1 - 1.6e-29 102.7 0.0 2.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58566.1 - 1.1e-06 27.8 0.0 2.4e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCH58566.1 - 0.0021 17.8 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCH58566.1 - 0.0025 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S11 PF00411.14 CCH58567.1 - 6.9e-05 22.9 0.1 0.00013 22.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 Bombesin PF02044.12 CCH58567.1 - 0.021 14.2 0.1 0.052 13.0 0.0 1.7 1 0 0 1 1 1 0 Bombesin-like peptide Ribosomal_L23 PF00276.15 CCH58568.1 - 2.4e-21 75.4 1.5 2.4e-21 75.4 1.0 1.9 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CCH58568.1 - 1.8e-19 69.4 9.7 1.8e-19 69.4 6.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain SSB PF00436.20 CCH58568.1 - 0.035 13.9 0.3 0.048 13.5 0.2 1.3 1 1 0 1 1 1 0 Single-strand binding protein family STN1_2 PF09170.5 CCH58568.1 - 0.039 13.7 0.1 0.054 13.2 0.1 1.2 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 ASL_C PF08328.6 CCH58568.1 - 0.092 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Ldh_1_N PF00056.18 CCH58569.1 - 3.6e-39 133.8 0.3 5.8e-39 133.1 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCH58569.1 - 6.5e-28 97.6 0.0 1.6e-27 96.3 0.0 1.7 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Paramyxo_PNT PF13825.1 CCH58569.1 - 0.072 12.2 0.2 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus RRM_1 PF00076.17 CCH58570.1 - 8.7e-38 127.8 0.5 1.2e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58570.1 - 2e-33 114.1 0.1 1.9e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58570.1 - 3.6e-13 49.1 0.1 4.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CCH58570.1 - 0.013 14.9 0.2 3.9 7.0 0.0 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain Ribosomal_S19e PF01090.14 CCH58571.1 - 6.4e-55 184.4 0.1 7.1e-55 184.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18e PF00828.14 CCH58572.1 - 3.6e-26 92.0 0.2 5.5e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 NTP_transf_2 PF01909.18 CCH58573.1 - 4.5e-17 62.1 1.1 8.9e-17 61.2 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCH58573.1 - 1.7e-14 53.4 0.0 5.8e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase RF-1 PF00472.15 CCH58574.1 - 2.9e-14 52.8 0.6 4.6e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 RF-1 domain Sec7_N PF12783.2 CCH58575.1 - 6.9e-29 100.4 9.0 6.9e-29 100.4 6.2 6.0 6 1 1 7 7 7 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Gti1_Pac2 PF09729.4 CCH58575.1 - 0.02 14.7 6.1 1.3 8.8 0.6 2.7 2 0 0 2 2 2 0 Gti1/Pac2 family Pex14_N PF04695.8 CCH58575.1 - 0.069 13.2 12.4 0.11 12.5 5.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.10 CCH58575.1 - 0.086 12.8 2.5 0.3 11.1 1.1 2.5 3 0 0 3 3 3 0 Ctr copper transporter family Med15 PF09606.5 CCH58575.1 - 0.68 8.0 25.7 1.1 7.3 17.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CCH58575.1 - 1 9.0 24.5 4.6 6.8 10.6 2.6 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 CCH58575.1 - 4.6 4.8 23.5 6.7 4.2 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RabGAP-TBC PF00566.13 CCH58576.1 - 1.6e-37 129.0 4.8 1.6e-37 129.0 3.4 4.3 3 2 0 3 3 3 1 Rab-GTPase-TBC domain TruB_N PF01509.13 CCH58577.1 - 1.3e-39 135.7 0.1 7.7e-38 129.9 0.0 2.5 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UvrD_C_2 PF13538.1 CCH58577.1 - 0.062 13.4 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Cyclin_N PF00134.18 CCH58578.1 - 1.1e-17 63.7 0.0 2.9e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCH58578.1 - 3.9e-12 46.8 0.0 3.9e-12 46.8 0.0 2.3 2 1 0 2 2 2 1 Cyclin Rcd1 PF04078.8 CCH58579.1 - 7.6e-119 395.3 3.7 9.1e-119 395.1 2.6 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SRX PF09201.5 CCH58579.1 - 0.055 13.1 0.0 9.7 5.8 0.0 2.3 2 0 0 2 2 2 0 SRX CorA PF01544.13 CCH58580.1 - 9.3e-45 152.8 6.9 1e-43 149.4 1.8 3.1 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2231 PF09990.4 CCH58580.1 - 0.015 15.6 0.5 0.027 14.8 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) PDT PF00800.13 CCH58581.1 - 5.7e-47 159.6 0.0 8e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 CCH58581.1 - 0.0046 16.4 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 ACT domain MepB PF08877.5 CCH58581.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 MepB protein 6PF2K PF01591.13 CCH58582.1 - 2.8e-37 127.9 10.5 1.1e-36 126.0 7.3 1.9 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CCH58582.1 - 0.00018 21.4 0.1 0.00052 19.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH58582.1 - 0.00038 21.2 0.0 0.00082 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCH58582.1 - 0.00093 18.4 0.0 0.0015 17.7 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 CCH58582.1 - 0.0074 16.1 2.9 0.0086 15.9 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 CCH58582.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCH58582.1 - 0.037 13.1 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 CCH58582.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 CCH58582.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CCH58582.1 - 0.1 12.8 0.1 0.28 11.3 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Abhydrolase_5 PF12695.2 CCH58583.1 - 1.1e-19 70.5 0.0 1.5e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH58583.1 - 1.3e-14 54.6 0.0 2.7e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCH58583.1 - 3.1e-08 33.1 0.0 9.5e-08 31.5 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CCH58583.1 - 1.1e-07 31.6 0.1 7.8e-06 25.6 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CCH58583.1 - 5.3e-05 22.7 0.0 0.00021 20.8 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CCH58583.1 - 0.00027 20.6 0.0 0.0012 18.5 0.0 2.0 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 CCH58583.1 - 0.0014 18.0 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.8 CCH58583.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF818 PF05677.7 CCH58583.1 - 0.002 16.9 0.6 0.0029 16.4 0.4 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 CCH58583.1 - 0.0071 15.6 0.0 0.05 12.8 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 CCH58583.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 CCH58583.1 - 0.018 14.4 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 CCH58583.1 - 0.019 14.5 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S28 PF05577.7 CCH58583.1 - 0.025 13.1 0.0 0.041 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AXE1 PF05448.7 CCH58583.1 - 0.049 12.1 0.0 0.14 10.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 CCH58583.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_3 PF07859.8 CCH58583.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Retrotrans_gag PF03732.12 CCH58584.1 - 6.4e-08 32.5 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCH58584.1 - 0.0023 17.7 0.6 0.0038 17.0 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle COPIIcoated_ERV PF07970.7 CCH58584.1 - 0.082 12.5 0.1 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum vesicle transporter ThiF PF00899.16 CCH58585.1 - 8.5e-35 119.5 0.0 1.4e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CCH58585.1 - 3.2e-22 77.8 0.0 6.7e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCH58585.1 - 2.7e-20 71.4 2.0 4.6e-20 70.7 1.4 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CCH58585.1 - 0.00012 22.0 0.3 0.00035 20.6 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain DUF730 PF05325.6 CCH58585.1 - 0.026 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF730) NAD_binding_7 PF13241.1 CCH58585.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 CCH58585.1 - 0.13 11.0 0.1 0.29 10.0 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RhoGAP PF00620.22 CCH58586.1 - 4.8e-26 91.2 0.0 7.5e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Sugar_tr PF00083.19 CCH58587.1 - 2e-86 290.3 31.6 2.4e-86 290.0 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58587.1 - 3.1e-25 88.6 48.8 1.5e-24 86.4 19.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCH58587.1 - 0.07 11.2 9.3 0.017 13.2 1.6 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector GTP_EFTU PF00009.22 CCH58588.1 - 9e-62 207.8 0.2 1.3e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCH58588.1 - 1.4e-36 124.6 0.1 4.4e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCH58588.1 - 8.5e-21 73.6 0.0 2.6e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCH58588.1 - 8.8e-14 51.1 0.0 3.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCH58588.1 - 5.1e-13 48.9 1.0 1.6e-12 47.3 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH58588.1 - 8.8e-05 22.4 0.1 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 CCH58588.1 - 0.11 12.2 0.1 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 SUKH-4 immunity protein Grp1_Fun34_YaaH PF01184.14 CCH58589.1 - 2.6e-59 200.0 18.4 3.3e-59 199.7 12.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4467 PF14729.1 CCH58589.1 - 0.068 13.5 0.7 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) DUF3483 PF11982.3 CCH58589.1 - 4.3 6.5 5.2 0.65 9.2 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) ApoLp-III PF07464.6 CCH58590.1 - 0.0096 15.9 1.7 0.0096 15.9 1.2 1.9 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) YmaF PF12788.2 CCH58590.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 YmaF family FTA4 PF13093.1 CCH58590.1 - 0.1 11.9 10.0 0.14 11.5 5.5 2.2 1 1 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 IF-2B PF01008.12 CCH58590.1 - 0.19 10.6 2.0 0.3 10.0 0.7 1.7 1 1 1 2 2 2 0 Initiation factor 2 subunit family DUF4200 PF13863.1 CCH58590.1 - 0.58 10.1 8.0 0.12 12.3 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 CCH58590.1 - 0.67 9.7 4.2 0.59 9.9 0.5 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.3 CCH58590.1 - 2 8.4 8.0 0.24 11.4 0.2 2.5 2 1 1 3 3 3 0 YlqD protein DUF4559 PF15112.1 CCH58590.1 - 5.6 6.0 11.1 2.2 7.3 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Iso_dh PF00180.15 CCH58591.1 - 4.8e-62 209.9 0.0 5.6e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ATP-synt_10 PF05176.9 CCH58592.1 - 1.2e-46 159.0 0.1 1.6e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Arrestin_N PF00339.24 CCH58593.1 - 2.6e-05 24.0 0.0 0.00017 21.4 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Peptidase_M16 PF00675.15 CCH58595.1 - 1.9e-32 112.0 0.7 9.7e-31 106.5 0.2 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCH58595.1 - 9.3e-30 103.6 2.1 5.4e-16 58.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF663 PF04950.7 CCH58596.1 - 7.8e-99 330.3 0.0 1.9e-98 329.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCH58596.1 - 5.8e-25 86.6 0.0 1.4e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C2H2_2 PF12756.2 CCH58597.1 - 6.3e-31 106.4 9.0 2.7e-28 98.0 0.6 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CCH58597.1 - 0.0036 17.5 7.4 0.68 10.4 0.7 3.3 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCH58597.1 - 0.0078 16.3 7.0 0.022 14.9 0.8 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CCH58597.1 - 0.012 15.9 1.7 0.012 15.9 1.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCH58597.1 - 0.037 14.1 1.3 0.037 14.1 0.9 3.8 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_5 PF13719.1 CCH58597.1 - 3.3 7.3 5.9 2.4 7.8 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Vac14_Fig4_bd PF11916.3 CCH58598.1 - 6.2e-71 237.2 6.6 6.2e-71 237.2 4.6 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CCH58598.1 - 3.5e-47 158.7 2.0 6.8e-39 132.1 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CCH58598.1 - 5.6e-08 32.2 6.7 0.00016 21.4 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 CCH58598.1 - 1.2e-05 25.4 0.4 0.052 13.8 0.0 4.8 5 0 0 5 5 5 1 HEAT repeats Cnd1 PF12717.2 CCH58598.1 - 1.7e-05 24.7 11.5 0.074 12.8 0.8 4.6 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CCH58598.1 - 0.00026 21.3 0.0 2.4 8.7 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat RasGEF_N_2 PF14663.1 CCH58598.1 - 0.0037 17.2 1.5 0.012 15.5 0.1 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain CFC PF09443.5 CCH58598.1 - 0.084 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) ParcG PF10274.4 CCH58598.1 - 0.1 12.4 2.6 1.1 9.1 0.1 3.6 4 0 0 4 4 4 0 Parkin co-regulated protein Arm PF00514.18 CCH58598.1 - 0.17 11.7 8.4 2.6 8.0 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FliL PF03748.9 CCH58599.1 - 0.067 13.1 0.2 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Rad52_Rad22 PF04098.10 CCH58600.1 - 5.4e-11 42.4 0.3 8.8e-11 41.7 0.1 1.3 1 1 0 1 1 1 1 Rad52/22 family double-strand break repair protein LeuA_dimer PF08502.5 CCH58600.1 - 0.1 12.3 0.5 0.56 9.9 0.0 2.1 2 1 0 2 2 2 0 LeuA allosteric (dimerisation) domain CRAL_TRIO PF00650.15 CCH58601.1 - 6e-41 139.5 0.0 9.7e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCH58601.1 - 1.2e-10 41.4 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH58601.1 - 1.6e-10 40.9 0.3 4.6e-10 39.4 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Ank_2 PF12796.2 CCH58602.1 - 2.6e-10 40.4 0.1 0.00027 21.1 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCH58602.1 - 5.4e-10 39.5 0.7 3.3e-06 27.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCH58602.1 - 1.6e-06 27.6 0.4 0.089 12.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat KilA-N PF04383.8 CCH58602.1 - 1.1e-05 25.0 2.0 0.00021 20.9 0.2 2.9 2 1 0 2 2 2 1 KilA-N domain Ank_5 PF13857.1 CCH58602.1 - 6.2e-05 23.1 1.3 0.13 12.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH58602.1 - 0.00054 19.9 0.5 0.97 9.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat SPATA24 PF15175.1 CCH58602.1 - 0.44 10.2 5.5 1.4 8.5 0.7 2.3 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 NTP_transferase PF00483.18 CCH58603.1 - 5.6e-50 169.9 0.0 7.5e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CCH58603.1 - 5.9e-11 41.3 7.7 2.2e-07 30.0 2.2 3.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCH58603.1 - 2.3e-10 40.7 0.0 3.5e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CCH58603.1 - 0.0042 16.6 8.4 0.038 13.5 1.4 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CCH58603.1 - 0.038 13.6 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase Bactofilin PF04519.8 CCH58603.1 - 0.097 12.6 1.9 0.17 11.8 1.3 1.4 1 0 0 1 1 1 0 Polymer-forming cytoskeletal FBPase PF00316.15 CCH58604.1 - 6.5e-131 435.9 0.0 7.8e-131 435.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Acyltransferase PF01553.16 CCH58605.1 - 7.1e-32 109.6 0.0 1.3e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase rve PF00665.21 CCH58608.1 - 1.3e-15 57.5 0.0 1.7e-13 50.7 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain La PF05383.12 CCH58609.1 - 4.3e-17 61.6 0.0 9.9e-17 60.5 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CCH58609.1 - 2e-05 24.4 0.1 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH58609.1 - 0.00021 20.8 0.6 0.0027 17.2 0.4 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1834 PF08873.6 CCH58609.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) zf-C2H2 PF00096.21 CCH58610.1 - 0.0023 18.1 3.6 0.0023 18.1 2.5 5.3 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCH58610.1 - 0.0043 16.8 1.0 0.0043 16.8 0.7 4.4 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCH58610.1 - 0.01 16.1 2.8 0.01 16.1 2.0 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH58610.1 - 0.014 15.6 3.7 0.014 15.6 2.6 5.0 4 1 1 5 5 5 0 Zinc-finger double domain HRXXH PF13933.1 CCH58610.1 - 0.12 11.7 3.4 0.21 10.9 2.4 1.3 1 0 0 1 1 1 0 Putative peptidase family Prok-RING_1 PF14446.1 CCH58610.1 - 0.2 11.4 7.0 1.2 8.9 0.7 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_jaz PF12171.3 CCH58610.1 - 0.21 11.7 0.3 0.21 11.7 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Herpes_capsid PF06112.6 CCH58610.1 - 2.4 8.1 13.5 2.2 8.3 0.5 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein zf-met PF12874.2 CCH58610.1 - 5.7 7.2 12.0 0.67 10.2 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 CCH58610.1 - 6.6 6.4 14.1 4.7 6.9 0.5 3.5 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Ribosomal_S8 PF00410.14 CCH58611.1 - 5.7e-26 90.8 0.1 7.9e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Glutaredoxin PF00462.19 CCH58612.1 - 0.00024 21.0 0.3 0.00043 20.2 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCH58612.1 - 0.045 13.4 0.3 0.058 13.0 0.2 1.2 1 0 0 1 1 1 0 Thioredoxin DUF2462 PF09495.5 CCH58613.1 - 1.9e-19 70.1 12.5 2.3e-19 69.8 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) GATase_5 PF13507.1 CCH58614.1 - 4.3e-95 317.5 0.1 6.5e-95 316.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CCH58614.1 - 3.2e-44 150.6 0.0 2e-26 92.8 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCH58614.1 - 6.6e-22 77.5 0.0 1.9e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PIN_4 PF13638.1 CCH58615.1 - 0.00032 20.7 0.4 0.00061 19.9 0.1 1.6 1 1 0 1 1 1 1 PIN domain Septin PF00735.13 CCH58616.1 - 3.8e-88 295.1 2.0 9e-88 293.9 1.4 1.6 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 CCH58616.1 - 5.3e-06 25.7 0.1 1.6e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCH58616.1 - 8.9e-06 25.2 4.6 0.00047 19.6 0.1 2.8 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCH58616.1 - 2.1e-05 24.4 0.3 2.1e-05 24.4 0.2 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CCH58616.1 - 0.0056 16.2 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CCH58616.1 - 0.0059 16.1 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 CCH58616.1 - 0.021 15.3 0.1 0.021 15.3 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 CCH58616.1 - 0.042 14.0 0.2 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCH58616.1 - 0.068 12.0 0.3 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 CCH58616.1 - 0.15 11.8 0.1 0.15 11.8 0.0 3.6 3 1 1 4 4 4 0 Dynamin family ABC_tran PF00005.22 CCH58616.1 - 0.27 11.5 4.1 0.27 11.5 0.2 2.7 2 1 0 2 2 2 0 ABC transporter EF-hand_6 PF13405.1 CCH58617.1 - 8.2e-07 28.3 0.6 0.088 12.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CCH58617.1 - 1e-05 25.5 3.3 0.0071 16.4 0.4 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CCH58617.1 - 0.0079 15.4 3.6 23 4.6 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CCH58617.1 - 0.1 12.2 1.0 3.8 7.2 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain pair Pkinase PF00069.20 CCH58618.1 - 1.4e-66 224.2 0.0 2.3e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58618.1 - 3.6e-50 170.4 0.0 1.1e-49 168.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CCH58618.1 - 6.2e-33 112.8 0.0 2e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 CCH58618.1 - 9.9e-11 41.3 0.8 4.1e-10 39.3 0.5 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCH58618.1 - 2.9e-08 33.7 0.5 2.9e-08 33.7 0.3 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CCH58618.1 - 1.1e-05 24.5 0.0 0.00036 19.5 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Atg14 PF10186.4 CCH58620.1 - 0.0037 16.2 7.6 0.054 12.4 4.9 2.3 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 CCH58620.1 - 0.021 14.8 2.9 0.037 14.0 2.0 1.4 1 0 0 1 1 1 0 YlqD protein Lyase_1 PF00206.15 CCH58621.1 - 1.3e-24 87.0 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CCH58621.1 - 7.6e-17 61.0 0.0 2.7e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Bromodomain PF00439.20 CCH58622.1 - 7e-28 96.3 10.4 1.3e-16 60.2 0.3 2.9 3 0 0 3 3 3 2 Bromodomain BAH PF01426.13 CCH58622.1 - 9.7e-25 86.6 5.0 3.6e-24 84.7 0.6 3.0 3 0 0 3 3 3 1 BAH domain AA_permease_2 PF13520.1 CCH58623.1 - 3.2e-84 282.9 49.1 3.9e-84 282.6 34.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCH58623.1 - 2.8e-20 72.1 42.7 4.2e-20 71.5 29.6 1.2 1 0 0 1 1 1 1 Amino acid permease eIF2A PF08662.6 CCH58624.1 - 1e-73 247.1 0.2 7.8e-73 244.3 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCH58624.1 - 0.0002 21.1 4.4 2.1 8.3 0.1 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2454 PF10521.4 CCH58626.1 - 1e-52 178.9 9.7 1.8e-52 178.1 6.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) IlvC PF01450.14 CCH58627.1 - 7.2e-47 158.9 0.0 1.3e-46 158.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 CCH58627.1 - 7.2e-45 152.3 0.0 1.1e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CCH58627.1 - 0.041 13.7 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase zf-C2H2_4 PF13894.1 CCH58628.1 - 0.047 14.0 12.6 4.7 7.7 0.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCH58628.1 - 0.063 13.1 5.7 0.11 12.4 1.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH58628.1 - 1.6 9.2 19.3 1.2 9.6 1.8 3.9 3 1 0 3 3 3 0 Zinc finger, C2H2 type Transaldolase PF00923.14 CCH58629.1 - 4.9e-99 331.0 1.8 5.6e-99 330.8 1.2 1.0 1 0 0 1 1 1 1 Transaldolase DUF4154 PF13689.1 CCH58629.1 - 0.087 12.4 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4154) Prok-TraM PF09228.5 CCH58630.1 - 0.0071 16.4 1.1 0.027 14.5 0.0 2.6 2 0 0 2 2 2 1 Prokaryotic Transcriptional repressor TraM DUF3552 PF12072.3 CCH58630.1 - 0.036 13.2 4.8 0.053 12.7 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) LRR_4 PF12799.2 CCH58631.1 - 0.00054 19.5 19.2 0.002 17.7 0.3 5.6 4 3 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCH58631.1 - 0.00078 19.2 8.0 6.4 7.1 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.2 CCH58631.1 - 0.0054 16.4 0.7 0.33 10.7 0.0 2.6 2 0 0 2 2 2 1 F-box-like Phage_pRha PF09669.5 CCH58631.1 - 0.045 14.1 0.1 0.32 11.3 0.0 2.6 1 1 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) LRR_1 PF00560.28 CCH58631.1 - 0.22 11.7 13.5 19 5.7 0.1 6.9 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.1 CCH58631.1 - 0.6 9.9 13.2 0.087 12.5 0.4 4.7 6 0 0 6 6 6 0 Leucine rich repeat Pkinase PF00069.20 CCH58632.1 - 7.1e-72 241.6 0.0 8.6e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58632.1 - 1.3e-31 109.5 0.0 1.9e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58632.1 - 0.0014 17.6 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH58632.1 - 0.0037 16.3 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH58632.1 - 0.029 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CN_hydrolase PF00795.17 CCH58633.1 - 9.5e-32 109.8 0.0 5.2e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Transposase_1 PF01359.13 CCH58633.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Transposase (partial DDE domain) zf-H2C2_2 PF13465.1 CCH58635.1 - 2e-05 24.6 2.7 2e-05 24.6 1.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCH58635.1 - 4.9e-05 23.4 19.0 6.2e-05 23.1 1.7 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCH58635.1 - 0.0026 17.8 0.5 0.0077 16.3 0.3 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCH58635.1 - 0.0055 16.9 0.7 0.0055 16.9 0.5 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger RNA_pol_Rpb1_6 PF04992.9 CCH58635.1 - 0.093 12.4 1.3 0.19 11.4 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 DUF377 PF04041.8 CCH58635.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF377) CENP-B_dimeris PF09026.5 CCH58635.1 - 0.15 12.2 6.8 0.3 11.3 4.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-met PF12874.2 CCH58635.1 - 0.34 11.1 4.6 0.088 13.0 0.7 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Clp1 PF06807.9 CCH58636.1 - 3.3e-06 27.0 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCH58636.1 - 4.8e-05 23.0 0.0 0.00054 19.6 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCH58636.1 - 0.0004 20.2 0.1 0.002 18.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH58636.1 - 0.037 14.8 0.0 0.23 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CCH58636.1 - 0.057 13.3 2.7 0.07 13.0 0.6 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CCH58636.1 - 0.064 13.5 0.3 0.37 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCH58636.1 - 0.09 12.3 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCH58636.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family KH_1 PF00013.24 CCH58638.1 - 2.4e-10 39.9 0.4 0.00016 21.2 0.0 4.9 5 0 0 5 5 5 2 KH domain KH_3 PF13014.1 CCH58638.1 - 4.9e-10 38.8 1.1 0.0018 17.8 0.0 5.5 5 0 0 5 5 5 2 KH domain YlbE PF14003.1 CCH58638.1 - 0.057 13.5 0.1 1.9 8.5 0.1 2.6 2 0 0 2 2 2 0 YlbE-like protein Phosphodiest PF01663.17 CCH58639.1 - 3.6e-10 39.7 0.6 5.2e-10 39.1 0.4 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCH58639.1 - 0.016 14.5 1.0 0.03 13.7 0.7 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Sulfatase PF00884.18 CCH58639.1 - 0.026 13.7 0.1 0.048 12.8 0.1 1.4 1 0 0 1 1 1 0 Sulfatase Cellulase PF00150.13 CCH58639.1 - 0.065 12.4 0.1 0.14 11.2 0.1 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 CCH58640.1 - 1e-38 132.9 29.6 1e-38 132.9 20.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58640.1 - 4e-10 38.8 35.2 3.7e-09 35.6 18.7 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCH58641.1 - 1e-30 106.6 25.3 1e-30 106.6 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58641.1 - 1.4e-09 37.0 11.3 1.4e-09 37.0 7.8 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58642.1 - 2e-41 141.8 29.9 2e-41 141.8 20.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58642.1 - 4.2e-13 48.6 6.2 4.2e-13 48.6 4.3 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CCH58642.1 - 0.00013 20.3 4.4 0.00025 19.3 3.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CCH58643.1 - 8.5e-42 143.1 32.7 8.5e-42 143.1 22.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58643.1 - 3.1e-11 42.5 9.0 3.1e-11 42.5 6.2 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter NADH-u_ox-rdase PF10785.4 CCH58643.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.6 4 1 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4131 PF13567.1 CCH58643.1 - 0.15 11.4 0.1 0.15 11.4 0.0 4.5 3 2 2 5 5 5 0 Domain of unknown function (DUF4131) AAA_2 PF07724.9 CCH58644.1 - 6.5e-46 156.3 0.1 8.4e-45 152.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCH58644.1 - 3.8e-23 81.1 0.8 1.6e-22 79.2 0.2 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCH58644.1 - 1.4e-21 77.0 3.7 9e-14 51.8 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.15 CCH58644.1 - 1.2e-15 57.1 4.9 1.9e-09 37.3 0.5 3.3 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 CCH58644.1 - 6e-15 55.1 0.0 1.3e-07 31.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CCH58644.1 - 2.8e-12 46.4 0.2 4e-08 32.9 0.0 3.0 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CCH58644.1 - 4.7e-10 39.7 4.9 0.00027 20.9 0.0 4.8 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 CCH58644.1 - 6.8e-08 32.7 0.2 0.0081 16.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 CCH58644.1 - 2.7e-05 23.0 2.4 0.2 10.3 0.0 3.7 4 0 0 4 4 4 2 TIP49 C-terminus Mg_chelatase PF01078.16 CCH58644.1 - 0.00016 20.9 0.0 0.32 10.1 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCH58644.1 - 0.00089 18.4 0.9 0.037 13.1 0.0 3.3 3 1 0 3 3 3 1 Zeta toxin Torsin PF06309.6 CCH58644.1 - 0.00091 19.1 0.0 0.0046 16.8 0.0 2.2 2 0 0 2 2 2 1 Torsin Arch_ATPase PF01637.13 CCH58644.1 - 0.00093 18.9 2.4 0.41 10.3 0.4 4.1 3 1 0 3 3 2 1 Archaeal ATPase AAA_3 PF07726.6 CCH58644.1 - 0.0011 18.5 0.0 0.3 10.6 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCH58644.1 - 0.0014 18.2 0.0 0.68 9.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CCH58644.1 - 0.0038 16.9 0.1 1.1 8.8 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 CCH58644.1 - 0.0096 16.7 7.9 0.76 10.6 0.0 4.6 4 2 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CCH58644.1 - 0.01 15.6 0.1 0.81 9.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 CCH58644.1 - 0.015 14.6 0.0 0.71 9.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CCH58644.1 - 0.051 13.1 0.0 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CCH58644.1 - 0.066 13.5 2.1 5.1 7.3 0.0 3.7 4 0 0 4 4 4 0 ABC transporter RNA_helicase PF00910.17 CCH58644.1 - 0.072 13.2 0.1 16 5.7 0.0 3.2 3 0 0 3 3 3 0 RNA helicase VTC PF09359.5 CCH58644.1 - 0.17 10.8 4.5 0.12 11.3 1.4 1.9 2 0 0 2 2 2 0 VTC domain AAA_18 PF13238.1 CCH58644.1 - 6.2 7.1 9.0 12 6.1 0.0 4.1 5 1 0 5 5 4 0 AAA domain RRM_1 PF00076.17 CCH58645.1 - 5.8e-31 105.9 3.0 5.6e-15 54.7 0.3 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58645.1 - 1.1e-20 73.3 0.4 4.2e-09 36.2 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58645.1 - 4.4e-19 68.0 0.7 1.7e-08 34.1 0.1 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCH58645.1 - 0.002 17.9 0.3 1.7 8.5 0.1 2.7 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 CCH58645.1 - 0.014 15.1 0.0 1.9 8.2 0.0 2.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF106 PF01956.11 CCH58646.1 - 4.5e-58 195.4 0.9 5.6e-58 195.1 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATP_bind_1 PF03029.12 CCH58647.1 - 4.4e-83 278.4 0.2 6.9e-83 277.8 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CCH58647.1 - 1.3e-08 34.4 0.3 3.8e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 CCH58647.1 - 5.2e-07 29.2 0.2 4.1e-06 26.3 0.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 CCH58647.1 - 2.2e-05 25.2 0.8 0.0012 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCH58647.1 - 0.0002 21.2 0.2 0.00065 19.6 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CCH58647.1 - 0.00026 20.6 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CCH58647.1 - 0.00027 20.4 0.1 0.032 13.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 CCH58647.1 - 0.00034 20.3 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 CCH58647.1 - 0.00038 20.6 0.0 0.0013 18.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain ArgK PF03308.11 CCH58647.1 - 0.00061 18.6 0.0 0.43 9.3 0.0 2.5 2 1 0 2 2 2 2 ArgK protein PduV-EutP PF10662.4 CCH58647.1 - 0.00064 19.2 0.0 0.012 15.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CCH58647.1 - 0.0011 18.2 0.1 0.023 13.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.14 CCH58647.1 - 0.0013 18.1 0.1 0.025 14.0 0.1 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCH58647.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH58647.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 CCH58647.1 - 0.01 15.5 0.3 0.036 13.7 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CCH58647.1 - 0.013 15.9 0.3 1.1 9.8 0.2 2.7 1 1 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 CCH58647.1 - 0.015 15.5 0.0 0.015 15.5 0.0 3.2 3 1 0 3 3 1 0 AAA domain RNA_helicase PF00910.17 CCH58647.1 - 0.017 15.2 0.6 0.27 11.4 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 CCH58647.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCH58647.1 - 0.028 13.6 0.1 0.35 10.0 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 CCH58647.1 - 0.028 13.6 0.0 3.3 6.9 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family PRK PF00485.13 CCH58647.1 - 0.04 13.4 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 CCH58647.1 - 0.05 13.4 1.9 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 YuiB PF14068.1 CCH58647.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative membrane protein AAA_10 PF12846.2 CCH58647.1 - 0.18 11.1 3.5 1.2 8.5 2.4 2.1 1 1 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 CCH58647.1 - 0.26 10.4 5.8 0.29 10.3 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit FadA PF09403.5 CCH58647.1 - 0.82 9.6 9.1 0.39 10.7 2.0 2.7 1 1 1 2 2 2 0 Adhesion protein FadA PAC2 PF09754.4 CCH58648.1 - 7.2e-21 75.0 0.2 1.7e-20 73.8 0.1 1.7 1 1 0 1 1 1 1 PAC2 family MGDG_synth PF06925.6 CCH58648.1 - 0.25 11.2 2.2 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase LSM PF01423.17 CCH58649.1 - 2e-17 62.5 0.5 2.4e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain Metallophos PF00149.23 CCH58651.1 - 1.5e-40 138.7 0.2 1.8e-40 138.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SRP40_C PF05022.7 CCH58652.1 - 0.13 12.7 0.1 9.4 6.8 0.0 2.5 2 0 0 2 2 2 0 SRP40, C-terminal domain ERGIC_N PF13850.1 CCH58652.1 - 0.15 12.0 0.7 0.52 10.3 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pentapeptide_3 PF13576.1 CCH58652.1 - 0.51 10.2 3.4 2.4 8.1 0.7 2.5 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Ham1p_like PF01725.11 CCH58653.1 - 3.4e-46 156.9 0.0 3.9e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF4570 PF15134.1 CCH58654.1 - 0.055 13.3 2.0 0.058 13.2 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DBINO PF13892.1 CCH58654.1 - 0.079 12.9 4.7 0.086 12.8 3.2 1.1 1 0 0 1 1 1 0 DNA-binding domain DUF3919 PF13057.1 CCH58654.1 - 0.13 11.7 0.3 0.13 11.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) RPEL PF02755.10 CCH58654.1 - 0.17 11.2 2.6 1.7 8.1 0.0 3.0 3 0 0 3 3 3 0 RPEL repeat YlqD PF11068.3 CCH58654.1 - 1.2 9.2 4.5 2.2 8.3 3.1 1.5 1 1 0 1 1 1 0 YlqD protein Y_phosphatase2 PF03162.8 CCH58655.1 - 1.7e-43 147.8 6.3 7.9e-42 142.4 4.4 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Phage_glycop_gL PF11108.3 CCH58655.1 - 0.023 14.6 0.7 0.051 13.5 0.3 1.7 1 1 0 1 1 1 0 Viral glycoprotein L Asp_protease PF09668.5 CCH58656.1 - 3.1e-52 175.3 0.2 5.1e-52 174.6 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 CCH58656.1 - 1.4e-09 37.4 0.1 2.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Asp_protease_2 PF13650.1 CCH58656.1 - 2e-08 34.6 0.7 5.4e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 CCH58656.1 - 5.4e-07 29.4 0.1 2.2e-06 27.5 0.1 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CCH58656.1 - 0.00019 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCH58656.1 - 0.00032 20.4 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UN_NPL4 PF11543.3 CCH58656.1 - 0.0094 16.2 0.1 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Glutaredoxin2_C PF04399.8 CCH58656.1 - 0.075 12.6 1.2 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain COX15-CtaA PF02628.10 CCH58657.1 - 1.7e-100 335.8 5.0 2e-100 335.5 3.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Pentapeptide_4 PF13599.1 CCH58657.1 - 0.0095 15.7 0.6 0.02 14.7 0.4 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) DUF747 PF05346.6 CCH58658.1 - 1.5e-87 293.7 17.3 2.2e-87 293.1 12.0 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF2116 PF09889.4 CCH58658.1 - 7.9 6.3 6.4 0.75 9.6 0.1 2.7 3 1 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_S13_N PF08069.7 CCH58659.1 - 1.9e-24 85.2 0.4 3.5e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CCH58659.1 - 2.1e-22 78.6 0.1 3.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Aminotran_1_2 PF00155.16 CCH58660.1 - 1.7e-69 234.5 0.0 2e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCH58660.1 - 0.0011 17.8 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 CCH58660.1 - 0.018 13.6 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.16 CCH58660.1 - 0.16 11.0 0.0 0.3 10.2 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase ABC_tran PF00005.22 CCH58661.1 - 5.6e-30 104.4 1.7 4.8e-18 65.7 0.0 3.2 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CCH58661.1 - 2.2e-16 60.7 10.7 1.6e-11 44.7 0.5 3.6 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCH58661.1 - 2.4e-06 26.8 9.7 8.1e-05 21.8 0.0 4.1 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CCH58661.1 - 5.2e-05 23.4 0.5 0.24 11.5 0.0 3.7 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCH58661.1 - 8.7e-05 22.8 0.2 0.32 11.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CCH58661.1 - 0.00055 19.7 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 CCH58661.1 - 0.00068 20.4 0.0 2.4 8.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCH58661.1 - 0.001 18.5 0.2 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CCH58661.1 - 0.0046 16.9 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCH58661.1 - 0.009 15.9 0.2 2.7 7.9 0.0 3.7 3 1 1 4 4 4 1 AAA domain AAA PF00004.24 CCH58661.1 - 0.017 15.3 0.7 17 5.5 0.0 4.2 2 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 CCH58661.1 - 0.026 13.7 0.1 12 5.0 0.0 3.1 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 CCH58661.1 - 0.045 13.3 0.1 4.1 6.9 0.0 3.2 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 CCH58661.1 - 0.088 12.4 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF4582 PF15189.1 CCH58661.1 - 0.089 12.0 0.7 4 6.6 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4582) DUF1068 PF06364.7 CCH58661.1 - 0.1 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Miro PF08477.8 CCH58661.1 - 0.12 12.8 0.0 2.6 8.5 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein AAA_16 PF13191.1 CCH58661.1 - 0.14 12.1 0.6 0.64 9.9 0.0 2.3 3 1 0 3 3 3 0 AAA ATPase domain UAF_Rrn10 PF05234.6 CCH58662.1 - 8e-32 109.7 0.1 1e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Nol1_Nop2_Fmu PF01189.12 CCH58663.1 - 4e-85 285.6 0.0 4e-69 233.1 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CCH58663.1 - 0.00026 21.0 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCH58663.1 - 0.05 14.1 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-UBR PF02207.15 CCH58664.1 - 2.1e-10 40.1 10.4 2.1e-10 40.1 7.2 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 CCH58664.1 - 0.033 13.8 1.3 0.033 13.8 0.9 4.0 3 1 0 3 3 3 0 PHD-finger Lon_C PF05362.8 CCH58665.1 - 1.2e-65 220.7 0.0 6e-65 218.3 0.0 2.2 3 0 0 3 3 3 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CCH58665.1 - 6.3e-34 117.4 9.7 6.3e-34 117.4 6.8 3.1 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CCH58665.1 - 2e-23 83.0 0.1 6.6e-23 81.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 CCH58665.1 - 3.8e-05 23.1 0.0 7.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 CCH58665.1 - 4.7e-05 23.1 0.0 0.00015 21.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CCH58665.1 - 7.7e-05 22.8 0.2 0.24 11.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.1 CCH58665.1 - 9.8e-05 22.4 0.1 0.0015 18.6 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH58665.1 - 0.00019 21.4 0.7 0.0034 17.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CCH58665.1 - 0.00061 20.6 1.5 0.0041 17.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CCH58665.1 - 0.0011 18.1 0.0 0.022 13.8 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCH58665.1 - 0.027 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 CCH58665.1 - 0.04 13.6 0.2 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCH58665.1 - 0.047 13.9 0.0 0.047 13.9 0.0 4.7 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.1 CCH58665.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rft-1 PF04506.8 CCH58666.1 - 6.6e-175 582.6 49.7 3.1e-174 580.3 34.5 1.8 1 1 0 1 1 1 1 Rft protein Phlebovirus_G2 PF07245.6 CCH58666.1 - 0.033 12.4 0.4 0.055 11.7 0.3 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 Exo_endo_phos PF03372.18 CCH58667.1 - 2e-16 60.7 0.0 2.7e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CCH58667.1 - 1.1e-14 54.0 0.7 1.8e-12 46.8 0.0 3.1 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CCH58667.1 - 7.9e-12 44.9 1.2 1.9e-11 43.7 0.8 1.7 1 0 0 1 1 1 1 GRF zinc finger AvrPphF-ORF-2 PF09143.5 CCH58668.1 - 0.017 14.8 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 AvrPphF-ORF-2 BNR PF02012.15 CCH58669.1 - 5.4e-16 55.7 40.6 0.43 10.6 0.4 13.2 13 0 0 13 13 13 10 BNR/Asp-box repeat Pkinase PF00069.20 CCH58670.1 - 1.5e-70 237.3 0.0 1.8e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58670.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58670.1 - 8.2e-05 21.6 0.0 0.0002 20.4 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CCH58670.1 - 0.035 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH58670.1 - 0.075 12.7 0.1 0.17 11.5 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Acid_PPase PF12689.2 CCH58671.1 - 1.8e-41 141.6 0.0 2.1e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase EMP24_GP25L PF01105.19 CCH58672.1 - 6.6e-43 146.5 0.0 7.6e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Metallophos PF00149.23 CCH58673.1 - 2.6e-44 151.0 0.1 3.1e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TIM21 PF08294.6 CCH58674.1 - 2.7e-37 127.6 0.0 3.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 CCH58674.1 - 0.16 11.4 0.8 0.94 8.9 0.1 2.4 2 1 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 Glyco_hydro_72 PF03198.9 CCH58675.1 - 9.6e-140 464.9 1.4 1.6e-139 464.3 1.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CCH58675.1 - 8.1e-16 58.2 0.2 1.8e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 X8 domain FYDLN_acid PF09538.5 CCH58675.1 - 0.013 16.0 5.8 0.031 14.8 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Glucan_synthase PF02364.10 CCH58676.1 - 0 1443.8 0.0 0 1443.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCH58676.1 - 1.6e-37 127.9 0.1 5.1e-37 126.3 0.0 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 FAM75 PF14650.1 CCH58676.1 - 0.17 11.2 0.2 0.29 10.4 0.2 1.3 1 0 0 1 1 1 0 FAM75 family Abhydrolase_6 PF12697.2 CCH58677.1 - 5.2e-30 105.0 0.0 6.2e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH58677.1 - 3.5e-14 52.7 0.0 5.8e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH58677.1 - 6.5e-09 35.6 0.0 2.7e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 CCH58677.1 - 1.8e-06 28.3 0.0 1.9e-06 28.2 0.0 1.2 1 1 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CCH58677.1 - 3.3e-06 26.8 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 CCH58677.1 - 4.9e-05 22.7 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 CCH58677.1 - 0.00032 20.2 0.0 0.00079 18.9 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 CCH58677.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 CCH58677.1 - 0.0058 16.0 0.1 0.035 13.5 0.0 2.1 1 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CCH58677.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 CCH58677.1 - 0.045 12.7 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydro_lipase PF04083.11 CCH58677.1 - 0.096 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DLH PF01738.13 CCH58677.1 - 0.1 11.8 0.0 1.1 8.4 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family NUC153 PF08159.7 CCH58678.1 - 5.1e-13 48.3 4.6 1.2e-12 47.1 3.2 1.7 1 0 0 1 1 1 1 NUC153 domain SNARE PF05739.14 CCH58679.1 - 2e-05 24.2 5.3 2e-05 24.2 3.7 3.3 4 0 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 CCH58679.1 - 0.027 14.5 6.1 0.14 12.2 0.4 2.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus zf-H2C2_2 PF13465.1 CCH58680.1 - 3.4e-10 39.7 18.0 6.8e-06 26.1 2.8 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCH58680.1 - 1.2e-07 31.6 14.9 0.00067 19.8 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH58680.1 - 9.4e-05 22.4 13.8 0.019 15.2 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCH58680.1 - 0.18 11.7 3.4 2.4 8.2 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1279 PF06916.8 CCH58681.1 - 5e-21 74.8 0.0 7e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L24e PF01246.15 CCH58682.1 - 8.5e-35 118.4 0.4 8.5e-35 118.4 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.7 CCH58682.1 - 0.12 11.8 1.3 0.16 11.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PVL_ORF50 PF07768.6 CCH58682.1 - 1.5 8.8 9.6 1.9 8.4 6.6 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family RR_TM4-6 PF06459.7 CCH58682.1 - 6.2 6.6 8.4 7.2 6.4 5.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CCH58683.1 - 0.00016 20.0 67.7 0.00017 19.9 46.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Glyco_hydro_63 PF03200.11 CCH58684.1 - 3.5e-218 726.3 13.6 1.8e-217 724.0 9.4 1.7 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CCH58684.1 - 1.1e-05 24.3 0.1 1.9e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Rrn6 PF10214.4 CCH58685.1 - 9.2e-111 371.2 31.5 1.1e-110 371.0 21.8 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.15 CCH58686.1 - 9.9e-97 322.5 0.3 1.5e-96 321.9 0.2 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CCH58686.1 - 1.4e-44 152.5 1.9 1.7e-44 152.2 0.4 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 CCH58686.1 - 0.075 12.2 0.1 0.29 10.3 0.1 2.0 1 1 0 1 1 1 0 PcrB family Med3 PF11593.3 CCH58687.1 - 2e-18 66.7 8.0 2e-18 66.7 5.6 4.3 1 1 2 3 3 3 2 Mediator complex subunit 3 fungal PsbW PF07123.7 CCH58687.1 - 2.5 8.1 6.6 9 6.3 4.6 1.9 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) FYVE PF01363.16 CCH58688.1 - 2.1e-14 53.1 9.2 4.3e-14 52.1 6.4 1.5 1 0 0 1 1 1 1 FYVE zinc finger STT3 PF02516.9 CCH58689.1 - 2e-130 436.0 53.3 2.3e-128 429.1 34.8 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 CCH58689.1 - 0.00046 20.1 12.6 0.00046 20.1 8.8 4.2 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Hamartin PF04388.7 CCH58689.1 - 0.45 9.1 1.5 0.64 8.6 1.0 1.1 1 0 0 1 1 1 0 Hamartin protein HSCB_C PF07743.8 CCH58690.1 - 5e-14 52.5 2.9 9.5e-14 51.6 1.6 1.8 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CCH58690.1 - 1.8e-11 43.6 1.3 1e-10 41.2 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain UVR PF02151.14 CCH58690.1 - 0.035 13.6 1.3 0.066 12.7 0.1 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif Aconitase PF00330.15 CCH58691.1 - 6.7e-189 628.1 0.2 8.1e-189 627.9 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCH58691.1 - 3.2e-44 150.2 0.0 6.2e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans PF04082.13 CCH58692.1 - 7.4e-22 77.4 5.6 7.4e-22 77.4 3.9 2.3 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH58692.1 - 1.6e-05 24.6 5.8 3e-05 23.8 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1-E2_ATPase PF00122.15 CCH58693.1 - 6.8e-60 201.9 7.2 6.8e-60 201.9 5.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCH58693.1 - 4.5e-24 86.0 0.1 1.1e-23 84.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH58693.1 - 3.1e-16 60.1 0.1 1.4e-15 57.9 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCH58693.1 - 1.1e-11 44.0 0.2 3.5e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCH58693.1 - 0.0012 18.4 0.1 0.003 17.1 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH58693.1 - 0.051 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Syntaxin_2 PF14523.1 CCH58694.1 - 0.022 14.7 4.7 0.051 13.6 2.2 2.4 1 1 0 1 1 1 0 Syntaxin-like protein UPF0149 PF03695.8 CCH58694.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0149) BDV_P24 PF06595.6 CCH58694.1 - 0.18 11.5 1.3 0.21 11.3 0.2 1.5 1 1 1 2 2 2 0 Borna disease virus P24 protein DUF4164 PF13747.1 CCH58694.1 - 0.2 11.8 1.8 4.9 7.3 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) V_ATPase_I PF01496.14 CCH58694.1 - 0.61 7.8 5.9 0.74 7.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 CCH58695.1 - 1.3e-16 59.7 0.5 5.4e-08 32.4 0.0 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat FAD-oxidase_C PF02913.14 CCH58696.1 - 1.6e-53 181.6 0.0 2.2e-53 181.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCH58696.1 - 6e-36 122.9 0.0 1.5e-35 121.7 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain RRM_1 PF00076.17 CCH58696.1 - 0.022 14.4 0.1 12 5.5 0.0 3.9 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.3 CCH58697.1 - 2.8e-16 59.6 10.7 4.6e-15 55.7 0.7 5.2 2 2 3 5 5 5 3 Protein of unknown function (DUF3602) Serglycin PF04360.7 CCH58697.1 - 0.042 13.5 2.6 0.083 12.6 1.8 1.5 1 0 0 1 1 1 0 Serglycin Glu_synthase PF01645.12 CCH58698.1 - 1.4e-155 517.7 0.0 7.8e-155 515.3 0.0 2.0 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CCH58698.1 - 1.1e-133 445.4 0.0 2.8e-133 444.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CCH58698.1 - 3.9e-114 380.7 0.0 1.6e-113 378.7 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 CCH58698.1 - 1.4e-57 193.9 1.2 2.5e-57 193.1 0.8 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CCH58698.1 - 3.4e-24 84.6 0.0 6.6e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CCH58698.1 - 1.5e-12 47.8 0.0 4.1e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH58698.1 - 5.2e-09 36.4 0.0 0.00019 21.5 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCH58698.1 - 1e-08 35.0 0.0 3.1e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCH58698.1 - 9.1e-07 29.1 0.1 0.0002 21.6 0.0 3.4 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCH58698.1 - 1.1e-05 24.6 0.0 2.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CCH58698.1 - 7.1e-05 21.8 0.1 0.00028 19.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCH58698.1 - 0.00019 20.0 0.4 0.00046 18.7 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CCH58698.1 - 0.00039 20.1 0.0 0.001 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 CCH58698.1 - 0.0008 18.5 0.2 0.0039 16.3 0.1 2.1 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 CCH58698.1 - 0.0011 18.1 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CCH58698.1 - 0.0051 15.7 0.0 0.0097 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CCH58698.1 - 0.0059 15.7 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GATase_6 PF13522.1 CCH58698.1 - 0.0065 16.4 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain NAD_binding_7 PF13241.1 CCH58698.1 - 0.02 15.1 0.0 11 6.3 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 CCH58698.1 - 0.023 15.1 0.7 0.099 13.0 0.0 2.5 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCH58698.1 - 0.03 14.1 0.1 0.096 12.5 0.0 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FMO-like PF00743.14 CCH58698.1 - 0.038 12.1 0.5 11 4.0 0.0 3.2 3 1 0 3 3 3 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 CCH58698.1 - 0.059 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FMN_dh PF01070.13 CCH58698.1 - 0.1 11.4 0.5 0.58 8.9 0.6 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PRELI PF04707.9 CCH58699.1 - 2.7e-44 150.4 1.3 3.3e-44 150.2 0.9 1.0 1 0 0 1 1 1 1 PRELI-like family DUF2963 PF11178.3 CCH58699.1 - 0.022 14.1 2.0 0.075 12.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) PTR2 PF00854.16 CCH58700.1 - 3.4e-56 190.6 16.0 4.6e-56 190.2 11.1 1.2 1 0 0 1 1 1 1 POT family DUF1129 PF06570.6 CCH58700.1 - 0.3 10.3 6.9 0.22 10.8 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) SRP40_C PF05022.7 CCH58701.1 - 7.1e-30 103.3 3.9 2.1e-29 101.8 2.7 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain Whi5 PF08528.6 CCH58702.1 - 6.5e-09 35.1 0.1 1.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Whi5 like LIM PF00412.17 CCH58703.1 - 8.8e-17 60.9 23.7 8.6e-10 38.5 6.0 2.5 2 0 0 2 2 2 2 LIM domain DUF3336 PF11815.3 CCH58704.1 - 1.5e-38 131.5 10.1 2.9e-38 130.6 7.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCH58704.1 - 1.4e-29 103.5 0.0 9.5e-29 100.7 0.0 2.3 3 0 0 3 3 3 1 Patatin-like phospholipase F-box-like PF12937.2 CCH58705.1 - 2.1e-08 33.7 0.1 4.9e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 CCH58705.1 - 1.6e-06 27.6 0.2 9.9e-06 25.1 0.1 2.4 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.1 CCH58705.1 - 1.7e-06 27.8 0.3 0.04 13.8 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.28 CCH58705.1 - 1.8e-06 27.4 0.2 5.2e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.12 CCH58705.1 - 2e-05 24.1 1.4 0.00083 19.0 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCH58705.1 - 0.00078 19.0 0.0 0.32 10.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCH58705.1 - 0.002 17.6 0.0 0.041 13.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Tfb4 PF03850.9 CCH58705.1 - 0.043 13.0 0.5 0.093 11.9 0.3 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 TPR_14 PF13428.1 CCH58705.1 - 0.062 13.9 0.0 16 6.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCH58705.1 - 0.095 13.4 0.0 0.28 11.9 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_6 PF13516.1 CCH58705.1 - 0.23 11.6 7.1 7.6 6.9 0.0 4.9 5 0 0 5 5 4 0 Leucine Rich repeat LRR_1 PF00560.28 CCH58705.1 - 0.7 10.1 8.5 3.5 8.0 0.0 5.4 7 1 0 7 7 5 0 Leucine Rich Repeat LRR_4 PF12799.2 CCH58705.1 - 0.72 9.5 12.9 17 5.1 0.3 5.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Zip PF02535.17 CCH58706.1 - 2.1e-40 138.7 14.1 1.7e-23 83.1 4.3 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter Claudin_2 PF13903.1 CCH58706.1 - 0.048 13.3 6.0 0.26 10.9 0.3 2.8 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4118 PF13493.1 CCH58706.1 - 3.9 7.7 14.5 0.17 12.0 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) U3_snoRNA_assoc PF08297.6 CCH58707.1 - 3.6e-18 65.5 6.8 3.6e-18 65.5 4.7 2.8 2 1 0 2 2 2 1 U3 snoRNA associated DUF1870 PF08965.5 CCH58707.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) Cas_GSU0053 PF09617.5 CCH58707.1 - 0.28 10.9 5.3 2.4 7.9 0.3 2.2 1 1 1 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) CLPTM1 PF05602.7 CCH58707.1 - 0.7 8.5 8.1 1.2 7.7 5.6 1.5 1 1 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) V_ATPase_I PF01496.14 CCH58707.1 - 6.9 4.3 14.6 7.9 4.1 10.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNARE_assoc PF09335.6 CCH58708.1 - 1.2e-14 54.5 5.9 1.2e-14 54.5 4.1 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4231 PF14015.1 CCH58708.1 - 0.016 15.1 10.6 3.6 7.6 3.2 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF1240 PF06836.7 CCH58708.1 - 1.8 8.8 6.6 2.6 8.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) BacteriocIIc_cy PF12173.3 CCH58708.1 - 2.9 8.0 11.5 1 9.4 0.2 3.8 5 0 0 5 5 5 0 Bacteriocin class IIc cyclic gassericin A-like PspB PF06667.7 CCH58708.1 - 4 7.4 7.1 1 9.3 0.2 3.0 3 0 0 3 3 3 0 Phage shock protein B Kin17_mid PF10357.4 CCH58709.1 - 4.1e-37 126.6 11.0 4.1e-37 126.6 7.6 2.3 2 1 1 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CCH58709.1 - 7.5e-06 25.9 3.9 7.5e-06 25.9 2.7 2.0 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCH58709.1 - 2.4e-05 24.3 4.1 2.4e-05 24.3 2.9 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCH58709.1 - 0.00042 20.3 1.3 0.00042 20.3 0.9 2.7 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) TFIID_90kDa PF04494.10 CCH58709.1 - 0.00062 19.8 2.2 0.00062 19.8 1.5 2.6 3 0 0 3 3 3 1 WD40 associated region in TFIID subunit zf-C2H2_4 PF13894.1 CCH58709.1 - 0.099 13.0 6.6 0.37 11.2 2.7 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH58709.1 - 0.87 10.0 9.2 0.28 11.6 3.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCH58709.1 - 0.88 9.5 4.8 6.5 6.8 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RNA_polI_A14 PF08203.6 CCH58709.1 - 3 8.1 5.7 30 4.9 0.1 3.5 1 1 2 3 3 3 0 Yeast RNA polymerase I subunit RPA14 zf-DBF PF07535.7 CCH58709.1 - 7.1 6.4 7.6 1.3 8.7 1.1 2.3 2 0 0 2 2 2 0 DBF zinc finger AKAP95 PF04988.7 CCH58709.1 - 8.2 6.1 16.5 0.052 13.3 4.2 2.5 1 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Peptidase_M48 PF01435.13 CCH58710.1 - 2.2e-30 105.8 0.0 3.2e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Ten_N PF06484.7 CCH58710.1 - 0.04 13.0 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Teneurin Intracellular Region MRP-L20 PF12824.2 CCH58711.1 - 3.2e-48 163.8 3.5 3.2e-48 163.8 2.4 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 CCH58711.1 - 0.03 14.1 0.3 0.078 12.7 0.0 1.8 2 1 0 2 2 2 0 Neugrin NTR2 PF15458.1 CCH58711.1 - 0.085 12.0 3.2 0.031 13.5 0.7 1.4 2 0 0 2 2 2 0 Nineteen complex-related protein 2 GTP_EFTU PF00009.22 CCH58712.1 - 7.9e-45 152.6 0.0 1.1e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CCH58712.1 - 1.1e-13 51.0 7.1 2.6e-13 49.9 5.0 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 CCH58712.1 - 1.5e-06 28.1 0.0 8.1e-06 25.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CCH58712.1 - 7.4e-05 22.7 0.0 0.00018 21.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 CCH58712.1 - 0.00082 19.4 0.0 0.0026 17.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Dynamin_N PF00350.18 CCH58712.1 - 0.0095 15.7 0.1 2.9 7.6 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CCH58712.1 - 0.014 15.8 0.5 0.11 12.9 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein Ras PF00071.17 CCH58712.1 - 0.024 14.0 0.1 0.32 10.3 0.0 2.3 2 0 0 2 2 2 0 Ras family Septin PF00735.13 CCH58712.1 - 0.029 13.3 0.0 0.061 12.3 0.0 1.4 1 0 0 1 1 1 0 Septin GTP_EFTU_D4 PF14578.1 CCH58712.1 - 0.065 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PBP1_TM PF14812.1 CCH58712.1 - 7.7 6.9 9.5 3.4 8.0 2.8 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Syntaxin-18_N PF10496.4 CCH58713.1 - 5.5e-13 48.5 1.2 5.5e-13 48.5 0.8 2.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 CCH58713.1 - 8.9e-06 25.3 6.4 8.9e-06 25.3 4.4 2.7 2 0 0 2 2 2 1 SNARE domain DUF2120 PF09893.4 CCH58713.1 - 0.02 14.8 2.9 0.02 14.8 2.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) SecG PF03840.9 CCH58713.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Dispanin PF04505.7 CCH58713.1 - 0.063 12.8 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DUF948 PF06103.6 CCH58713.1 - 0.81 9.5 10.1 6.8 6.6 0.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) VIT1 PF01988.14 CCH58713.1 - 2.7 7.4 5.4 16 4.8 3.8 2.3 1 1 0 1 1 1 0 VIT family Laminin_II PF06009.7 CCH58713.1 - 6.9 6.4 14.4 0.3 10.8 3.5 2.9 2 1 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.1 CCH58713.1 - 8.5 6.7 19.2 0.85 9.9 3.2 3.4 2 1 1 3 3 3 0 Snapin/Pallidin Sec20 PF03908.8 CCH58713.1 - 8.8 6.1 12.7 0.48 10.1 1.2 3.4 3 1 1 4 4 4 0 Sec20 DASH_Dad2 PF08654.5 CCH58714.1 - 3.8e-27 94.2 3.8 4.6e-27 94.0 2.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 CCH58714.1 - 0.00025 20.5 2.4 0.00032 20.2 1.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 B56 PF01603.15 CCH58714.1 - 0.0066 15.1 1.6 0.0072 14.9 0.4 1.4 1 1 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) PhageMin_Tail PF10145.4 CCH58714.1 - 0.061 12.9 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Phage-related minor tail protein THF_DHG_CYH PF00763.18 CCH58715.1 - 9.5e-19 67.5 0.0 1.9e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CCH58715.1 - 2.7e-18 65.5 0.0 4.5e-10 38.8 0.0 2.5 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lactamase_B_2 PF12706.2 CCH58716.1 - 2.5e-33 115.2 0.5 6e-33 114.0 0.3 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CCH58716.1 - 1.6e-23 81.8 0.0 3.9e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Rpn3_C PF08375.6 CCH58716.1 - 0.063 13.6 0.2 0.19 12.1 0.1 1.7 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal Vps5 PF09325.5 CCH58717.1 - 1.4e-35 122.6 5.1 2.6e-35 121.7 3.5 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCH58717.1 - 7e-22 77.3 0.7 2.4e-21 75.6 0.1 2.2 2 0 0 2 2 2 1 PX domain RNF111_N PF15303.1 CCH58717.1 - 0.16 11.4 4.2 0.047 13.2 0.8 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase Arkadia N-terminus Alg6_Alg8 PF03155.10 CCH58718.1 - 6e-156 519.9 41.6 7e-156 519.7 28.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 CCH58718.1 - 0.00068 19.2 0.7 0.00068 19.2 0.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) Cytochrom_C1 PF02167.10 CCH58720.1 - 4.6e-82 274.9 0.0 5.4e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CCH58720.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CCH58720.1 - 0.8 10.5 4.9 0.19 12.5 0.6 2.3 2 1 0 2 2 2 0 Cytochrome c PHD PF00628.24 CCH58721.1 - 9.2e-05 22.0 10.5 0.00041 19.9 7.3 2.0 1 1 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 CCH58721.1 - 0.0014 18.5 2.4 0.0014 18.5 1.6 2.1 2 0 0 2 2 2 1 RING-like domain zf-HC5HC2H PF13771.1 CCH58721.1 - 0.0039 17.2 3.2 0.0083 16.2 2.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CCH58721.1 - 0.015 15.3 2.6 0.03 14.3 1.8 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF960 PF06124.6 CCH58721.1 - 0.03 14.5 0.0 0.11 12.7 0.0 2.0 1 1 1 2 2 2 0 Staphylococcal protein of unknown function (DUF960) RPAP2_Rtr1 PF04181.8 CCH58721.1 - 0.86 9.7 5.4 2.2 8.4 1.2 2.5 2 0 0 2 2 2 0 Rtr1/RPAP2 family Pkinase PF00069.20 CCH58722.1 - 2e-53 181.2 0.1 2.5e-53 180.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58722.1 - 7.2e-16 58.0 0.0 1.1e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH58722.1 - 3.2e-06 27.0 0.0 1.2e-05 25.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCH58722.1 - 0.02 14.4 0.2 0.049 13.1 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF2340 PF10209.4 CCH58724.1 - 6.6e-52 174.8 2.7 7.9e-52 174.5 1.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) NOB1_Zn_bind PF08772.6 CCH58725.1 - 1.4e-25 88.9 0.9 2.9e-25 87.8 0.6 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 CCH58725.1 - 7.7e-05 22.5 7.6 7.7e-05 22.5 5.3 2.6 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator zf-RING_3 PF14369.1 CCH58725.1 - 0.024 14.6 1.5 0.048 13.6 1.0 1.4 1 0 0 1 1 1 0 zinc-finger CIAPIN1 PF05093.8 CCH58726.1 - 3.8e-32 110.3 4.1 4.1e-32 110.2 1.9 1.8 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Prok-E2_D PF14460.1 CCH58726.1 - 0.059 12.8 0.1 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic E2 family D zf-AN1 PF01428.11 CCH58727.1 - 8.4e-11 41.5 7.4 1.5e-10 40.7 5.1 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CCH58727.1 - 0.79 9.9 6.5 1.2 9.4 4.5 1.3 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Hydrolase_6 PF13344.1 CCH58728.1 - 5.2e-24 84.0 0.0 1e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH58728.1 - 3.4e-21 74.7 0.0 7.7e-21 73.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CCH58728.1 - 2.9e-07 30.8 0.0 0.041 14.0 0.0 3.2 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCH58728.1 - 0.0024 17.5 1.8 0.29 10.6 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH58728.1 - 0.007 16.8 0.0 0.34 11.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3658 PF12395.3 CCH58728.1 - 0.03 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function PNK3P PF08645.6 CCH58728.1 - 0.048 13.0 0.0 0.58 9.5 0.0 2.4 2 2 0 2 2 2 0 Polynucleotide kinase 3 phosphatase TP_methylase PF00590.15 CCH58729.1 - 4.2e-37 127.9 0.0 6e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Shikimate_DH PF01488.15 CCH58729.1 - 0.0062 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TRAPP PF04051.11 CCH58730.1 - 7.4e-37 126.2 0.0 9.1e-37 125.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RTA1 PF04479.8 CCH58731.1 - 1.9e-67 227.0 9.7 2.8e-67 226.5 6.7 1.2 1 0 0 1 1 1 1 RTA1 like protein COX2-transmemb PF09125.5 CCH58731.1 - 0.14 11.7 3.1 0.46 10.0 0.2 2.8 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane UTP15_C PF09384.5 CCH58732.1 - 0.23 11.1 3.0 0.47 10.1 0.1 2.5 3 0 0 3 3 3 0 UTP15 C terminal XRN_N PF03159.13 CCH58733.1 - 8.4e-106 352.6 0.0 2.7e-105 351.0 0.0 1.9 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Pmp3 PF01679.12 CCH58735.1 - 2e-17 62.6 4.7 2.1e-17 62.5 3.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MNSV_P7B PF06692.6 CCH58736.1 - 0.0028 17.3 3.6 0.43 10.4 0.1 2.3 2 0 0 2 2 2 2 Melon necrotic spot virus P7B protein LpxD PF04613.9 CCH58736.1 - 0.046 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD CUE PF02845.11 CCH58738.1 - 5.3e-10 38.5 0.0 1.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain Lactamase_B PF00753.22 CCH58739.1 - 2.4e-18 66.4 0.5 3.4e-18 65.9 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCH58739.1 - 7.7e-05 22.3 0.2 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.15 CCH58740.1 - 2.4e-47 160.8 0.0 5.1e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCH58740.1 - 3.7e-29 102.6 0.0 6.2e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCH58740.1 - 6.5e-20 71.0 10.6 1.3e-10 41.2 0.1 3.5 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 CCH58740.1 - 4e-15 56.4 0.0 8.8e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCH58740.1 - 2.3e-05 24.1 8.9 0.0066 16.0 0.1 4.3 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase CK_II_beta PF01214.13 CCH58741.1 - 1.9e-73 245.9 0.0 2.2e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Hira PF07569.6 CCH58742.1 - 4.8e-82 274.4 0.3 1.4e-80 269.6 0.3 2.6 2 0 0 2 2 2 2 TUP1-like enhancer of split tRNA-synt_1b PF00579.20 CCH58743.1 - 3.2e-78 262.8 0.0 4.2e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) FAD_binding_6 PF00970.19 CCH58744.1 - 4.4e-05 23.5 0.0 0.0003 20.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain WD40 PF00400.27 CCH58745.1 - 5.1e-55 181.5 27.4 3.1e-10 39.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCH58745.1 - 0.076 11.7 3.4 0.27 9.9 0.6 2.5 2 1 1 3 3 3 0 Coatomer WD associated region IKI3 PF04762.7 CCH58745.1 - 0.24 9.1 5.2 0.32 8.7 1.4 2.3 2 1 0 2 2 2 0 IKI3 family SNARE PF05739.14 CCH58746.1 - 1.6e-17 62.9 6.0 1.6e-17 62.9 4.1 3.3 3 1 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 CCH58746.1 - 2.6e-12 46.6 12.1 2.6e-12 46.6 8.4 2.9 1 1 2 3 3 3 1 Syntaxin-like protein VP9 PF09625.5 CCH58746.1 - 0.012 15.3 0.1 0.031 14.0 0.1 1.6 1 0 0 1 1 1 0 VP9 protein DUF427 PF04248.7 CCH58746.1 - 0.075 12.7 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF427) COX2 PF00116.15 CCH58746.1 - 0.079 12.7 0.5 0.17 11.7 0.4 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, periplasmic domain MCPsignal PF00015.16 CCH58746.1 - 0.45 10.0 20.3 0.54 9.7 5.4 3.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0118 PF01594.11 CCH58746.1 - 1.5 7.7 10.5 0.16 10.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF20 Reprolysin_4 PF13583.1 CCH58746.1 - 3 7.3 7.2 0.11 12.0 0.3 2.0 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like zf-C3HC4_3 PF13920.1 CCH58747.1 - 5.9e-10 38.6 9.6 5.9e-10 38.6 6.6 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH58747.1 - 0.001 19.0 9.4 0.001 19.0 6.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH58747.1 - 0.016 15.0 9.5 0.016 15.0 6.6 2.7 4 0 0 4 4 4 0 Ring finger domain Pex2_Pex12 PF04757.9 CCH58748.1 - 1.2e-28 100.1 9.4 1.8e-28 99.5 6.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CCH58748.1 - 1.7e-06 27.5 17.1 2.5e-06 27.0 11.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH58748.1 - 2.6e-06 27.1 15.9 4e-06 26.5 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH58748.1 - 2.8e-06 27.2 18.8 4.5e-06 26.5 13.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH58748.1 - 4.3e-05 23.1 13.0 7.9e-05 22.2 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCH58748.1 - 4.9e-05 22.8 18.1 7.9e-05 22.2 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH58748.1 - 0.0012 18.6 18.2 0.0024 17.6 12.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CCH58748.1 - 0.15 12.2 11.7 0.29 11.2 8.1 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CCH58748.1 - 0.47 10.2 9.7 0.87 9.4 6.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCH58748.1 - 1.7 8.3 13.3 2.7 7.7 7.7 2.5 2 1 1 3 3 3 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CCH58748.1 - 2.6 7.6 11.5 8.2 6.0 8.0 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 XPG_N PF00752.12 CCH58749.1 - 7.3e-30 103.2 0.0 2.3e-29 101.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCH58749.1 - 1.6e-21 76.1 0.2 7.1e-21 74.0 0.0 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 CCH58749.1 - 1.5e-06 28.3 0.5 1.6e-05 25.0 0.0 2.8 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 CCH58749.1 - 0.012 15.1 0.2 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing HHH_2 PF12826.2 CCH58749.1 - 0.029 14.2 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif bZIP_C PF12498.3 CCH58749.1 - 2.6 9.3 13.6 5.3 8.3 2.2 3.1 2 1 0 2 2 2 0 Basic leucine-zipper C terminal DcpS_C PF11969.3 CCH58750.1 - 1.7e-29 102.3 0.3 3.3e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 CCH58750.1 - 1.7e-26 92.7 1.9 3.2e-26 91.8 0.2 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Sedlin_N PF04628.8 CCH58750.1 - 0.056 13.3 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region YpM PF09144.5 CCH58750.1 - 2.3 8.1 5.0 11 6.0 0.0 3.5 3 1 1 4 4 4 0 Yersinia pseudotuberculosis mitogen MBOAT PF03062.14 CCH58751.1 - 6.9e-58 196.2 13.5 6.9e-58 196.2 9.4 2.5 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.14 CCH58752.1 - 6.9e-89 297.9 0.0 8e-89 297.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Kinetocho_Slk19 PF12709.2 CCH58753.1 - 0.013 15.5 3.5 0.013 15.5 2.4 4.6 3 1 1 5 5 5 0 Central kinetochore-associated DUF1664 PF07889.7 CCH58753.1 - 3.8 7.3 13.5 0.11 12.2 3.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CBM_21 PF03370.8 CCH58754.1 - 1.7e-24 85.9 4.7 4.9e-24 84.4 3.3 1.8 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 CCH58754.1 - 0.018 15.1 1.7 3.3 7.8 0.7 2.7 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) MCM PF00493.18 CCH58755.1 - 3.5e-142 473.0 0.6 4.6e-142 472.6 0.4 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCH58755.1 - 2.7e-21 76.3 1.8 2.7e-21 76.3 1.2 2.5 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CCH58755.1 - 2e-06 27.5 0.0 4.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCH58755.1 - 2.2e-06 26.9 0.0 0.00064 18.9 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCH58755.1 - 0.00066 19.2 0.0 0.0023 17.5 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCH58755.1 - 0.027 13.9 0.1 1.2 8.6 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 CCH58755.1 - 0.032 14.6 1.1 0.34 11.3 0.8 2.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Herpes_UL49_1 PF03117.9 CCH58755.1 - 0.072 12.1 1.3 10 5.1 0.1 2.8 3 0 0 3 3 3 0 UL49 family LSM PF01423.17 CCH58756.1 - 1.4e-17 62.9 0.8 1.8e-17 62.6 0.5 1.1 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 CCH58757.1 - 6.6e-41 139.6 1.0 1.5e-40 138.4 0.7 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH58757.1 - 1.1e-22 79.6 0.0 6e-11 42.0 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCH58757.1 - 6.3e-07 29.3 8.2 2.8e-06 27.3 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 CCH58757.1 - 0.0023 16.0 3.0 0.0033 15.5 2.1 1.2 1 0 0 1 1 1 1 CDC45-like protein DnaI_N PF07319.6 CCH58757.1 - 0.0041 17.3 1.7 0.81 9.9 0.2 3.1 2 0 0 2 2 2 2 Primosomal protein DnaI N-terminus CPSF73-100_C PF11718.3 CCH58758.1 - 4.1e-61 206.0 4.5 4.1e-61 206.0 3.2 1.9 1 1 1 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CCH58758.1 - 5.5e-31 107.1 1.7 7.2e-31 106.7 0.0 2.1 3 0 0 3 3 3 1 Beta-Casp domain Lactamase_B PF00753.22 CCH58758.1 - 2.2e-16 60.0 0.7 4e-16 59.2 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCH58758.1 - 1.3e-12 47.6 1.0 3.3e-11 43.0 0.3 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CCH58758.1 - 3.9e-11 42.5 0.0 9.3e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CCH58758.1 - 2.3e-06 27.4 0.4 9.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SecA_DEAD PF07517.9 CCH58758.1 - 0.043 13.1 1.2 0.075 12.3 0.8 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain DUF2899 PF11449.3 CCH58758.1 - 0.081 12.0 0.2 0.64 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2899) Zn_clus PF00172.13 CCH58759.1 - 1.8e-06 27.7 10.6 4.1e-06 26.6 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 CCH58760.1 - 1.2e-34 119.7 0.0 3.4e-34 118.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Hus1 PF04005.7 CCH58761.1 - 5.1e-24 84.7 3.8 3.7e-18 65.5 0.8 2.3 2 0 0 2 2 2 2 Hus1-like protein Helitron_like_N PF14214.1 CCH58761.1 - 0.014 15.1 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus GTP_EFTU PF00009.22 CCH58762.1 - 2.4e-50 170.6 0.0 5.4e-50 169.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CCH58762.1 - 4.9e-32 110.0 7.6 4.9e-32 110.0 5.3 2.0 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CCH58762.1 - 4.7e-10 39.2 0.0 1.8e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCH58762.1 - 1.2e-06 28.5 3.1 7.4e-06 25.9 0.3 3.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH58762.1 - 2.6e-05 24.1 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 CCH58762.1 - 0.00018 20.9 1.3 0.00059 19.2 0.0 2.2 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 CCH58762.1 - 0.0064 16.3 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 CCH58762.1 - 0.0076 15.4 0.1 0.063 12.5 0.0 2.4 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF619 PF04768.8 CCH58762.1 - 0.0076 15.6 1.9 0.067 12.6 1.3 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF619) ATP_sub_h PF10775.4 CCH58763.1 - 5.4e-13 48.4 0.4 8.3e-13 47.8 0.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h zf-U1 PF06220.7 CCH58764.1 - 5.6e-18 64.2 6.0 1.3e-17 63.0 4.1 1.6 1 0 0 1 1 1 1 U1 zinc finger DUF737 PF05300.6 CCH58764.1 - 0.0068 16.3 5.8 0.012 15.5 4.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF737) GTP_EFTU PF00009.22 CCH58765.1 - 8.6e-61 204.6 0.3 1.2e-60 204.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCH58765.1 - 3.9e-27 94.2 0.0 9e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCH58765.1 - 1.2e-21 76.5 2.1 3.2e-21 75.2 1.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCH58765.1 - 2.4e-05 23.8 0.4 5.4e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCH58765.1 - 3.8e-05 23.6 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCH58765.1 - 0.0023 18.4 0.0 0.0038 17.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CCH58765.1 - 0.078 12.4 0.3 9 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 CCH58765.1 - 0.085 11.9 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding AAA_29 PF13555.1 CCH58765.1 - 0.12 11.9 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.14 CCH58765.1 - 0.21 11.0 1.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 CCH58765.1 - 0.26 10.6 2.0 9.9 5.5 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain G_glu_transpept PF01019.16 CCH58766.1 - 1.9e-126 422.5 0.0 2.5e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1708 PF08101.6 CCH58767.1 - 5e-85 285.8 6.4 5e-85 285.8 4.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) FAM150 PF15129.1 CCH58768.1 - 0.21 11.4 1.1 0.38 10.6 0.1 1.7 1 1 1 2 2 2 0 FAM150 family Cellulase PF00150.13 CCH58769.1 - 4.6e-11 42.4 0.5 7.7e-11 41.7 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.18 CCH58771.1 - 3.9e-64 216.2 0.1 3.9e-64 216.2 0.1 2.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH58771.1 - 8.4e-11 41.5 0.0 2.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCH58771.1 - 4.3e-05 23.1 3.8 0.00013 21.6 2.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCH58771.1 - 8.3e-05 22.3 3.7 0.0002 21.1 2.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH58771.1 - 0.00022 21.2 1.2 0.0008 19.3 0.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH58771.1 - 0.004 16.8 0.4 0.004 16.8 0.3 2.9 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.1 CCH58771.1 - 0.036 13.6 0.5 0.11 12.0 0.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 CCH58771.1 - 0.1 12.2 8.7 0.017 14.7 3.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH58771.1 - 0.18 11.7 5.0 0.75 9.7 3.1 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Spb1_C PF07780.7 CCH58771.1 - 7 6.0 16.6 0.33 10.4 3.0 3.3 2 1 1 3 3 3 0 Spb1 C-terminal domain Cornichon PF03311.9 CCH58772.1 - 3.7e-49 166.0 9.1 4.2e-49 165.9 6.3 1.0 1 0 0 1 1 1 1 Cornichon protein TraL PF07178.6 CCH58772.1 - 3.2 7.8 6.8 6.6 6.8 0.1 2.5 3 0 0 3 3 3 0 TraL protein RRM_1 PF00076.17 CCH58774.1 - 1.7e-30 104.4 0.0 4.9e-16 58.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58774.1 - 3.8e-16 58.8 0.0 1.1e-09 38.0 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58774.1 - 1.2e-11 44.3 0.0 0.017 14.9 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSP1_C PF07462.6 CCH58774.1 - 0.033 12.5 7.7 0.41 8.9 0.3 2.2 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Shadoo PF14999.1 CCH58774.1 - 9.2 6.1 15.7 2.1 8.2 1.4 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective CBS PF00571.23 CCH58775.1 - 5.7e-22 77.2 0.1 2.4e-05 24.0 0.1 5.1 4 1 0 4 4 4 4 CBS domain HUN PF08729.5 CCH58776.1 - 1.4e-12 47.2 0.1 5.6e-12 45.3 0.1 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain YlzJ PF14035.1 CCH58776.1 - 0.013 15.4 0.1 0.092 12.8 0.0 2.3 2 0 0 2 2 2 0 YlzJ-like protein Kinetochor_Ybp2 PF08568.5 CCH58777.1 - 3.1e-129 432.0 27.2 3.5e-129 431.9 18.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin FliT PF05400.8 CCH58777.1 - 0.075 13.4 0.2 0.36 11.2 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT APG12 PF04110.8 CCH58778.1 - 7.8e-30 102.9 0.3 1.4e-29 102.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 CCH58778.1 - 0.0094 15.9 0.2 0.21 11.5 0.1 2.2 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like CPSase_L_D2 PF02786.12 CCH58779.1 - 2.2e-83 278.7 0.1 3.8e-83 277.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCH58779.1 - 4.4e-67 225.3 0.0 8.5e-67 224.3 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCH58779.1 - 1.2e-35 121.8 0.1 2.6e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCH58779.1 - 2.3e-30 104.7 0.0 1.7e-29 101.9 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCH58779.1 - 2.6e-26 92.7 0.0 5e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 CCH58779.1 - 1.4e-18 66.3 2.9 1.4e-18 66.3 2.0 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCH58779.1 - 1.5e-18 66.6 0.0 7e-18 64.4 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCH58779.1 - 4.7e-17 62.3 0.2 8.7e-17 61.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCH58779.1 - 4.6e-09 35.7 2.1 0.00048 19.7 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CCH58779.1 - 2.4e-07 30.2 0.0 5.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCH58779.1 - 4.6e-07 29.4 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.1 CCH58779.1 - 6.6e-05 23.2 1.0 0.11 12.7 0.1 3.1 3 0 0 3 3 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 CCH58779.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 CCH58779.1 - 0.00034 19.8 0.1 0.3 10.1 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 CCH58779.1 - 0.0005 19.4 0.3 0.073 12.3 0.1 2.4 2 0 0 2 2 2 1 HlyD family secretion protein RimK PF08443.6 CCH58779.1 - 0.00091 18.7 0.0 0.004 16.6 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain RnfC_N PF13375.1 CCH58779.1 - 0.036 13.7 2.2 0.29 10.8 0.2 2.7 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 CCH58779.1 - 0.082 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Transket_pyr PF02779.19 CCH58780.1 - 2.8e-45 153.9 0.0 9.6e-45 152.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCH58780.1 - 1.9e-37 127.9 0.0 4.7e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain AMP-binding PF00501.23 CCH58781.1 - 6e-76 255.5 0.0 7.5e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCH58781.1 - 1.1e-10 42.2 0.0 2.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Tyr-DNA_phospho PF06087.7 CCH58782.1 - 4.4e-68 229.9 0.4 5.6e-68 229.5 0.3 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CCH58782.1 - 0.0062 16.2 0.2 0.047 13.4 0.0 2.4 2 0 0 2 2 2 1 PLD-like domain Methyltransf_11 PF08241.7 CCH58783.1 - 0.011 16.1 0.0 0.036 14.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CCH58783.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_31 PF01055.21 CCH58784.1 - 1.3e-141 472.4 0.6 1.9e-141 471.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCH58784.1 - 2.1e-21 75.5 0.1 9.8e-21 73.3 0.1 2.3 1 0 0 1 1 1 1 Galactose mutarotase-like EBP PF05241.7 CCH58785.1 - 0.023 13.6 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Emopamil binding protein ABC1 PF03109.11 CCH58787.1 - 7.5e-33 113.0 0.0 1.9e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 ABC1 family YjgP_YjgQ PF03739.9 CCH58787.1 - 0.063 12.0 0.9 0.13 10.9 0.1 1.7 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family FAD_binding_2 PF00890.19 CCH58788.1 - 1.4e-122 409.5 2.3 2.2e-122 408.8 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CCH58788.1 - 2.8e-48 163.0 0.4 4.5e-48 162.3 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CCH58788.1 - 9.9e-07 28.8 0.6 0.00024 21.0 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCH58788.1 - 3e-06 26.5 0.5 0.00068 18.7 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CCH58788.1 - 5.9e-06 25.3 2.5 0.0029 16.5 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CCH58788.1 - 9.7e-06 24.7 0.6 0.00012 21.1 0.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCH58788.1 - 0.0042 16.2 0.1 0.0083 15.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CCH58788.1 - 0.022 13.2 0.1 0.12 10.7 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_6 PF00970.19 CCH58789.1 - 1.4e-23 82.9 0.0 2.4e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCH58789.1 - 5.7e-22 78.3 0.0 8.1e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCH58789.1 - 0.001 18.9 0.0 0.0065 16.3 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Carb_kinase PF01256.12 CCH58790.1 - 1.1e-57 195.1 0.1 1.5e-57 194.7 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CCH58790.1 - 7.4e-07 28.6 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase LRR_6 PF13516.1 CCH58791.1 - 0.02 14.8 16.0 8.9 6.7 0.4 6.8 6 0 0 6 6 6 0 Leucine Rich repeat DUF3414 PF11894.3 CCH58792.1 - 0 1354.3 73.2 0 1354.1 50.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) zf-H2C2 PF09337.5 CCH58793.1 - 0.034 13.5 0.1 0.088 12.2 0.0 1.7 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger rve PF00665.21 CCH58793.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain PIP5K PF01504.13 CCH58794.1 - 1.9e-65 220.4 1.7 6.1e-65 218.8 1.2 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CCH58794.1 - 9.2e-26 90.5 1.9 1.9e-25 89.4 0.1 2.1 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CCH58794.1 - 5.8e-17 61.3 10.8 5.8e-17 61.3 7.5 2.5 3 0 0 3 3 3 1 FYVE zinc finger Peptidase_M28 PF04389.12 CCH58795.1 - 7.9e-37 126.7 0.0 1.2e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nucleoporin_FG PF13634.1 CCH58796.1 - 2e-56 189.1 385.9 7.7e-12 45.4 25.7 11.9 2 2 7 10 10 10 8 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CCH58796.1 - 4.6e-32 110.7 0.1 1.5e-31 109.0 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin autopeptidase Swi3 PF07962.7 CCH58797.1 - 7.9e-27 92.7 0.3 7.9e-27 92.7 0.2 2.7 2 1 1 3 3 3 1 Replication Fork Protection Component Swi3 Peptidase_S64 PF08192.6 CCH58797.1 - 3.2 5.9 15.9 4.2 5.5 11.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 BOP1NT PF08145.7 CCH58798.1 - 3.3e-102 341.6 9.1 6.8e-102 340.6 6.3 1.6 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CCH58798.1 - 2.3e-27 93.8 10.2 1.1e-11 44.1 0.6 7.6 7 1 0 7 7 7 4 WD domain, G-beta repeat Colicin_D PF11429.3 CCH58798.1 - 0.057 13.5 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Colicin D Rb_C PF08934.5 CCH58798.1 - 6.4 6.3 6.9 15 5.2 4.8 1.6 1 0 0 1 1 1 0 Rb C-terminal domain GAF_2 PF13185.1 CCH58799.1 - 6.2e-07 30.0 0.0 8.5e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 CCH58799.1 - 0.00021 21.4 0.0 0.00024 21.2 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 CCH58799.1 - 0.0011 19.0 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 GAF domain DUF825 PF05695.7 CCH58799.1 - 0.26 8.6 2.9 0.33 8.3 2.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Scramblase PF03803.10 CCH58800.1 - 1.9e-69 233.1 0.4 2.6e-69 232.6 0.3 1.2 1 0 0 1 1 1 1 Scramblase SRX PF09201.5 CCH58801.1 - 9.5e-50 168.0 5.7 2.3e-49 166.8 3.9 1.7 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 CCH58801.1 - 2.2e-48 164.3 0.6 6.4e-46 156.2 0.4 2.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 CCH58801.1 - 2.2e-06 27.6 0.2 1e-05 25.5 0.2 2.3 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 CCH58801.1 - 8.3e-06 24.7 0.3 5.9e-05 21.9 0.0 2.4 2 1 0 2 2 2 1 ArgK protein CbiA PF01656.18 CCH58801.1 - 2.9e-05 23.5 0.1 7.8e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP-alpha_N PF04086.8 CCH58801.1 - 0.00043 19.7 7.1 0.00043 19.7 4.9 2.3 1 1 1 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal ArsA_ATPase PF02374.10 CCH58801.1 - 0.00059 18.9 4.1 0.036 13.1 0.0 3.4 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_16 PF13191.1 CCH58801.1 - 0.0033 17.4 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Fer4_NifH PF00142.13 CCH58801.1 - 0.0039 16.4 0.0 0.0085 15.3 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 CCH58801.1 - 0.0059 16.7 0.2 0.079 13.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 CCH58801.1 - 0.0078 15.9 0.0 0.027 14.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCH58801.1 - 0.0088 15.9 0.4 0.21 11.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CCH58801.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain NAD_binding_10 PF13460.1 CCH58801.1 - 0.032 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding AAA_25 PF13481.1 CCH58801.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CCH58801.1 - 0.38 10.5 12.6 3.4 7.4 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF87 MRP-S28 PF10213.4 CCH58801.1 - 0.49 10.4 4.1 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein DEAD PF00270.24 CCH58802.1 - 4.2e-23 81.6 0.0 2.1e-22 79.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CCH58802.1 - 2.1e-14 53.8 0.1 5.1e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CCH58802.1 - 1.2e-12 47.4 0.1 3.3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CCH58802.1 - 0.00011 22.1 1.5 0.00028 20.8 1.0 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like TFR_dimer PF04253.10 CCH58802.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain PAP2 PF01569.16 CCH58803.1 - 2.8e-20 72.3 0.4 2.8e-20 72.3 0.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily DUF443 PF04276.7 CCH58803.1 - 0.1 12.0 4.5 0.18 11.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF443) O-antigen_lig PF13425.1 CCH58803.1 - 0.23 11.4 7.4 2.2 8.2 1.8 3.1 2 1 1 3 3 3 0 O-antigen ligase like membrane protein RseC_MucC PF04246.7 CCH58803.1 - 0.77 9.3 2.7 0.82 9.2 0.3 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC YfhO PF09586.5 CCH58803.1 - 1.1 7.1 7.8 0.62 8.0 2.6 1.9 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF836 PF05768.9 CCH58805.1 - 3.9e-16 59.0 0.5 5.5e-16 58.5 0.3 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 CCH58805.1 - 0.00013 21.9 0.1 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 CCH58805.1 - 0.021 15.0 0.2 0.028 14.5 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCH58805.1 - 0.024 14.7 0.7 0.03 14.4 0.5 1.2 1 0 0 1 1 1 0 Thioredoxin-like Inositol_P PF00459.20 CCH58806.1 - 1.6e-63 214.5 0.0 1.8e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FAD_binding_1 PF00667.15 CCH58807.1 - 1.2e-66 224.3 0.0 2.1e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCH58807.1 - 3.9e-27 95.0 0.8 6.6e-27 94.2 0.6 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCH58807.1 - 8e-21 74.6 0.0 1.9e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.5 CCH58807.1 - 0.04 12.6 0.0 0.08 11.6 0.0 1.4 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) RAG2_PHD PF13341.1 CCH58807.1 - 0.051 13.5 0.1 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 RAG2 PHD domain HAD_2 PF13419.1 CCH58808.1 - 1.6e-14 54.5 0.0 2.5e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH58808.1 - 7.4e-06 25.5 0.1 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCH58808.1 - 2.1e-05 25.0 0.0 0.0003 21.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH58808.1 - 0.0048 17.0 0.0 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 CCH58809.1 - 7.8e-20 71.5 0.0 1.2e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCH58809.1 - 5.7e-13 48.6 0.4 8.3e-12 44.8 0.0 2.6 3 0 0 3 3 3 1 3' exoribonuclease family, domain 2 Inositol_P PF00459.20 CCH58811.1 - 2.4e-63 213.9 0.0 2.7e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.15 CCH58812.1 - 2.5e-147 491.0 1.7 3.7e-147 490.4 1.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CCH58812.1 - 7.5e-87 291.5 4.7 1.1e-86 291.0 1.9 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCH58812.1 - 2.5e-21 76.0 0.3 6e-21 74.8 0.2 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 CCH58812.1 - 0.0091 16.2 0.1 1.5 9.1 0.0 2.9 2 1 0 2 2 2 1 HEAT repeats MFS_1 PF07690.11 CCH58813.1 - 2.8e-36 124.9 40.5 2.8e-36 124.9 28.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58813.1 - 0.00021 20.0 39.6 0.0041 15.7 27.5 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter FSH1 PF03959.8 CCH58814.1 - 1.4e-61 207.6 0.0 1.5e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCH58814.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 CCH58814.1 - 0.0079 15.9 0.0 0.66 9.6 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 CCH58814.1 - 0.0081 15.6 0.1 0.17 11.3 0.1 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Calcipressin PF04847.7 CCH58815.1 - 4.1e-20 72.1 0.5 7e-20 71.3 0.3 1.3 1 1 0 1 1 1 1 Calcipressin DEAD PF00270.24 CCH58815.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Elf1 PF05129.8 CCH58816.1 - 1.4e-29 101.5 1.3 1.9e-29 101.1 0.9 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.5 CCH58816.1 - 0.19 11.2 2.0 2 7.9 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.1 CCH58816.1 - 0.22 11.5 0.3 0.22 11.5 0.2 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger BUD22 PF09073.5 CCH58816.1 - 1 8.3 6.6 0.98 8.4 4.6 1.1 1 0 0 1 1 1 0 BUD22 Ribosomal_L44 PF00935.14 CCH58816.1 - 2.1 8.3 6.8 53 3.9 4.7 2.4 1 1 0 1 1 1 0 Ribosomal protein L44 CDC45 PF02724.9 CCH58816.1 - 4.9 5.0 6.8 5.7 4.8 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L1 PF00687.16 CCH58817.1 - 7e-41 139.9 8.4 1.2e-40 139.2 5.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MatE PF01554.13 CCH58818.1 - 3.2e-62 208.9 33.4 2.4e-33 115.0 6.9 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 CCH58818.1 - 4.9e-05 23.1 9.6 4.9e-05 23.1 6.7 4.1 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain DUF4490 PF14892.1 CCH58818.1 - 0.2 11.3 0.2 0.38 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) ADH_zinc_N_2 PF13602.1 CCH58819.1 - 2.7e-09 37.9 0.0 5.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCH58819.1 - 1.1e-05 24.9 0.0 3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH58819.1 - 0.0002 21.0 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 CCH58820.1 - 2.8e-68 229.9 1.1 2.8e-68 229.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58820.1 - 4.8e-31 107.7 0.6 9.9e-31 106.7 0.0 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 CCH58820.1 - 0.012 15.3 1.3 0.1 12.3 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCH58820.1 - 0.025 13.6 0.6 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spt20 PF12090.3 CCH58820.1 - 0.066 12.5 6.0 0.14 11.4 4.1 1.5 1 0 0 1 1 1 0 Spt20 family UPF0560 PF10577.4 CCH58820.1 - 0.23 9.6 5.8 0.32 9.1 4.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DPPIV_N PF00930.16 CCH58821.1 - 1.2e-100 336.5 11.6 1.2e-100 336.5 8.1 1.6 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCH58821.1 - 9.1e-50 168.8 0.9 2e-49 167.7 0.6 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCH58821.1 - 6.2e-08 32.5 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH58821.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family ATP-synt_C PF00137.16 CCH58822.1 - 1.4e-27 95.3 29.6 6.7e-19 67.5 5.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C GHMP_kinases_N PF00288.21 CCH58823.1 - 2.2e-13 50.0 0.0 4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCH58823.1 - 0.00044 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16 PF00675.15 CCH58824.1 - 1.8e-43 147.8 0.2 1.4e-41 141.7 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCH58824.1 - 2.3e-32 112.1 0.1 8.6e-32 110.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF530 PF04409.7 CCH58824.1 - 0.061 11.4 0.5 0.12 10.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Myosin_head PF00063.16 CCH58825.1 - 1e-229 764.1 24.5 1e-229 764.1 17.0 3.5 3 2 1 4 4 4 1 Myosin head (motor domain) Phage_GP20 PF06810.6 CCH58825.1 - 0.00021 20.7 14.5 0.00021 20.7 10.1 15.5 3 2 13 17 17 17 5 Phage minor structural protein GP20 Myosin_N PF02736.14 CCH58825.1 - 0.0037 16.8 0.0 0.0098 15.5 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Ras PF00071.17 CCH58826.1 - 5.3e-16 58.4 0.3 1.7e-14 53.5 0.2 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CCH58826.1 - 4.4e-08 33.6 3.1 1.1e-07 32.3 0.3 2.8 2 1 0 2 2 2 1 Miro-like protein DUF605 PF04652.11 CCH58826.1 - 2.4 7.4 16.5 3.3 7.0 11.5 1.2 1 0 0 1 1 1 0 Vta1 like SRPRB PF09439.5 CCH58827.1 - 1.7e-58 196.8 0.4 2.6e-58 196.1 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCH58827.1 - 6.9e-10 38.9 0.6 1.4e-09 37.9 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CCH58827.1 - 1e-08 34.6 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCH58827.1 - 1.8e-08 33.8 0.2 2e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH58827.1 - 4.3e-06 26.2 0.0 0.00075 18.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCH58827.1 - 0.0002 21.8 0.0 0.00037 20.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 CCH58827.1 - 0.00078 19.0 0.2 0.0055 16.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 CCH58827.1 - 0.0012 18.0 0.1 0.0021 17.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCH58827.1 - 0.0016 17.6 0.1 0.0042 16.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 CCH58827.1 - 0.016 15.0 0.1 0.027 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CCH58827.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 CCH58827.1 - 0.051 13.8 0.1 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CCH58827.1 - 0.06 13.0 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B HIM1 PF08732.5 CCH58828.1 - 3.6e-11 42.1 0.0 3.8e-09 35.4 0.0 2.5 1 1 1 2 2 2 2 HIM1 NAD_binding_10 PF13460.1 CCH58828.1 - 1.2e-08 35.1 0.0 1.9e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCH58828.1 - 2.5e-05 23.8 0.0 5.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCH58828.1 - 0.046 14.0 0.2 0.26 11.5 0.0 2.3 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Arrestin_C PF02752.17 CCH58829.1 - 1e-23 83.9 0.1 1e-23 83.9 0.1 3.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCH58829.1 - 2.1e-13 50.3 0.1 2.7e-09 37.0 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCH58829.1 - 0.00018 21.0 0.1 0.00055 19.4 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like TIP120 PF08623.5 CCH58830.1 - 2.4e-07 30.4 0.9 1.7e-06 27.7 0.3 2.6 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) Rho_N PF07498.7 CCH58831.1 - 0.067 12.9 0.4 0.16 11.7 0.3 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain MFS_1 PF07690.11 CCH58832.1 - 2.3e-26 92.3 28.6 2.3e-26 92.3 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH58832.1 - 3.5e-11 42.3 34.4 1.3e-08 33.8 4.0 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 CCH58832.1 - 5.8e-06 26.0 3.0 3.8e-05 23.3 0.5 2.6 2 0 0 2 2 2 1 MFS_1 like family Oxidored_FMN PF00724.15 CCH58833.1 - 1.9e-119 398.6 0.0 2.2e-119 398.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2414 PF10309.4 CCH58833.1 - 0.026 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) RusA PF05866.6 CCH58834.1 - 0.011 16.1 0.6 0.23 11.8 0.1 2.7 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA TMF_TATA_bd PF12325.3 CCH58836.1 - 4.5e-35 120.0 20.0 4.5e-35 120.0 13.9 5.9 2 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CCH58836.1 - 1.6e-05 24.5 20.2 1.6e-05 24.5 14.0 10.1 5 3 7 12 12 12 4 TATA element modulatory factor 1 DNA binding Pex14_N PF04695.8 CCH58839.1 - 6.5e-32 110.4 1.3 6.5e-32 110.4 0.9 3.7 4 1 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Tox-WTIP PF15654.1 CCH58839.1 - 0.072 12.7 0.2 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Reo_sigmaC PF04582.7 CCH58839.1 - 1 8.4 10.1 0.13 11.4 4.0 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 CCH58839.1 - 1.1 8.8 21.6 0.33 10.5 11.6 2.6 1 1 1 2 2 2 0 IncA protein V_ATPase_I PF01496.14 CCH58839.1 - 1.1 7.0 13.8 2.1 6.0 9.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 CCH58839.1 - 2.8 7.7 14.0 32 4.3 1.5 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) K167R PF08065.7 CCH58839.1 - 3 7.9 12.3 2.1 8.4 5.2 2.7 2 1 0 3 3 3 0 K167R (NUC007) repeat L31 PF09784.4 CCH58839.1 - 4.7 7.3 6.0 4.3 7.4 2.2 2.5 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 ORF6C PF10552.4 CCH58839.1 - 5.1 6.8 25.2 1.5 8.5 1.7 4.1 3 1 1 4 4 4 0 ORF6C domain NIR_SIR PF01077.17 CCH58841.1 - 1e-53 180.8 0.0 1.3e-44 151.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CCH58841.1 - 1e-25 89.1 0.1 2e-13 49.7 0.0 3.1 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CCH58841.1 - 1.1e-23 83.7 0.0 2.2e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAAA-beta PF15508.1 CCH58841.1 - 0.015 15.6 0.1 0.14 12.4 0.0 2.7 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Chalcone PF02431.10 CCH58842.1 - 1.3e-42 145.5 0.0 1.7e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase VWA_2 PF13519.1 CCH58843.1 - 2.4e-11 44.0 0.1 3.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 CCH58843.1 - 6.4e-10 38.9 0.3 9.6e-10 38.3 0.2 1.2 1 0 0 1 1 1 1 Ssl1-like Ku_N PF03731.10 CCH58843.1 - 0.014 14.7 1.5 0.069 12.5 1.0 2.1 1 1 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain UIM PF02809.15 CCH58843.1 - 0.027 13.9 1.5 0.073 12.6 1.1 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosomal_S18 PF01084.15 CCH58843.1 - 0.029 14.2 0.1 0.49 10.2 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S18 NUDIX PF00293.23 CCH58844.1 - 4.4e-05 23.1 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3113 PF11310.3 CCH58844.1 - 0.082 12.6 0.6 0.27 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) PMT PF02366.13 CCH58845.1 - 2.8e-81 272.5 24.8 2.8e-81 272.5 17.2 2.5 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCH58845.1 - 7.9e-19 67.9 0.7 2e-18 66.6 0.3 1.8 1 1 1 2 2 2 1 MIR domain Mgm101p PF06420.7 CCH58846.1 - 1.8e-90 300.8 0.1 2.3e-90 300.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Pkinase PF00069.20 CCH58847.1 - 1.9e-68 230.4 0.0 3.3e-68 229.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58847.1 - 3.1e-31 108.3 0.0 5.5e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCH58847.1 - 4.7e-12 46.2 3.7 4.7e-12 46.2 2.5 3.4 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCH58847.1 - 2.5e-09 36.5 0.0 5.4e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCH58847.1 - 0.015 14.6 0.0 0.041 13.2 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HSF_DNA-bind PF00447.12 CCH58848.1 - 1.1e-34 118.6 3.0 3.2e-34 117.2 1.9 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 CCH58848.1 - 7.9e-26 90.2 0.2 2.1e-25 88.8 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Methyltransf_26 PF13659.1 CCH58848.1 - 0.0045 17.0 0.3 0.013 15.5 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain TFIIA PF03153.8 CCH58848.1 - 7.2 6.3 10.7 1.5 8.5 5.0 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit 5-FTHF_cyc-lig PF01812.15 CCH58849.1 - 1.3e-35 122.8 0.0 1.8e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.14 CCH58850.1 - 2.9e-30 105.4 0.0 3.5e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Flocculin PF00624.13 CCH58851.1 - 7.5e-22 76.8 145.2 2.7e-09 36.6 10.4 26.9 27 3 3 30 30 30 11 Flocculin repeat PA14 PF07691.7 CCH58851.1 - 8.2e-11 41.7 0.5 1.2e-09 37.9 0.0 3.5 3 0 0 3 3 3 1 PA14 domain Urm1 PF09138.6 CCH58851.1 - 0.1 12.7 0.4 0.4 10.8 0.3 2.0 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Flocculin PF00624.13 CCH58852.1 - 9.9e-32 108.5 84.2 2.6e-12 46.3 12.3 11.3 10 1 2 12 12 12 4 Flocculin repeat PA14 PF07691.7 CCH58852.1 - 1.2e-07 31.4 1.6 1.8e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 PA14 domain MORN_2 PF07661.8 CCH58852.1 - 2.1 8.6 2.9 7.2 6.9 2.0 1.9 1 0 0 1 1 1 0 MORN repeat variant Zn_clus PF00172.13 CCH58853.1 - 9.6e-08 31.8 10.4 1.8e-07 30.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CesA PF11439.3 CCH58853.1 - 0.01 15.7 0.9 0.033 14.0 0.2 2.2 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA Transp_cyt_pur PF02133.10 CCH58854.1 - 1.1e-71 241.6 33.9 1.6e-71 241.2 23.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATG_C PF09333.6 CCH58855.1 - 4.9e-27 93.9 0.0 9.6e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 ATG C terminal domain ATG2_CAD PF13329.1 CCH58855.1 - 4.6e-25 88.0 1.3 4.6e-25 88.0 0.9 4.0 4 0 0 4 4 4 1 Autophagy-related protein 2 CAD motif Fe_hyd_lg_C PF02906.9 CCH58856.1 - 3.6e-63 213.4 0.0 4.8e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_C1_2 PF03051.10 CCH58857.1 - 1.1e-163 544.8 3.3 1.4e-163 544.4 2.3 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CCH58857.1 - 0.00017 21.5 0.7 0.36 10.6 0.0 3.1 3 1 0 3 3 3 2 Papain family cysteine protease Peptidase_S8 PF00082.17 CCH58858.1 - 4.3e-57 193.4 0.1 6.5e-57 192.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CCH58858.1 - 1.8e-25 88.5 0.6 3.6e-24 84.3 0.2 2.5 2 0 0 2 2 2 1 Proprotein convertase P-domain RIC3 PF15361.1 CCH58858.1 - 4.9e-05 23.6 0.0 9.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 Pex14_N PF04695.8 CCH58858.1 - 0.01 15.8 0.6 0.024 14.7 0.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 CCH58858.1 - 0.04 13.9 1.4 0.077 13.0 0.1 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 CCH58858.1 - 0.072 13.2 0.3 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) PBP1_TM PF14812.1 CCH58858.1 - 0.15 12.4 1.9 0.39 11.0 0.0 2.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_M56 PF05569.6 CCH58858.1 - 0.21 10.4 0.0 0.41 9.5 0.0 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 Adeno_E1A PF02703.9 CCH58859.1 - 0.018 14.5 2.0 0.022 14.2 1.1 1.4 1 1 0 1 1 1 0 Early E1A protein DUF1250 PF06855.7 CCH58859.1 - 0.04 13.4 0.1 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) PA-IIL PF07472.6 CCH58859.1 - 0.075 13.2 7.5 9.9 6.4 6.6 2.2 2 0 0 2 2 2 0 Fucose-binding lectin II (PA-IIL) Med16 PF11635.3 CCH58860.1 - 5.6e-166 553.6 22.7 8.7e-166 553.0 15.7 1.3 1 0 0 1 1 1 1 Mediator complex subunit 16 Clathrin_bdg PF15045.1 CCH58860.1 - 0.0028 17.1 0.5 0.011 15.2 0.3 2.1 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Globin PF00042.17 CCH58861.1 - 0.013 15.8 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 Globin EXOSC1 PF10447.4 CCH58863.1 - 4.7e-30 103.3 0.0 1e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 CRAL_TRIO PF00650.15 CCH58864.1 - 6.6e-38 129.6 0.0 1.1e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH58864.1 - 4.8e-10 39.4 0.1 4.8e-10 39.4 0.0 3.0 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Elongin_A PF06881.6 CCH58865.1 - 1.3e-16 60.9 5.4 2.6e-13 50.3 0.1 2.8 2 0 0 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A GST_C PF00043.20 CCH58866.1 - 3.6e-20 71.7 0.0 7.9e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCH58866.1 - 3.6e-17 62.3 0.0 6.4e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCH58866.1 - 2.6e-10 40.1 0.0 5.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCH58866.1 - 7.8e-09 35.6 0.0 1.5e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCH58866.1 - 0.0004 20.2 0.0 0.00082 19.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SID PF11778.3 CCH58867.1 - 3.5e-22 78.7 8.8 3.5e-22 78.7 6.1 3.0 3 0 0 3 3 3 1 Septation initiation MbeD_MobD PF04899.7 CCH58867.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.4 2 1 2 4 4 4 0 MbeD/MobD like DUF1515 PF07439.6 CCH58867.1 - 0.65 9.8 13.7 0.32 10.8 1.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) G-patch PF01585.18 CCH58868.1 - 1.9e-09 37.1 2.2 4.1e-09 36.0 1.5 1.6 1 0 0 1 1 1 1 G-patch domain Gryzun-like PF12742.2 CCH58868.1 - 0.073 12.8 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Rap1-DNA-bind PF09197.5 CCH58869.1 - 1.9e-36 124.8 7.4 1.3e-32 112.4 0.2 3.5 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 CCH58869.1 - 4.5e-24 84.1 0.0 1.7e-23 82.2 0.0 2.1 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 CCH58869.1 - 7.4e-10 38.7 0.3 9.4e-07 28.7 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 CCH58869.1 - 1.6e-09 37.4 0.1 1.2e-05 25.0 0.1 3.1 2 0 0 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_6 PF13921.1 CCH58869.1 - 0.0019 18.2 2.9 0.26 11.4 0.0 3.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain RabGAP-TBC PF00566.13 CCH58870.1 - 4.8e-30 104.6 11.1 4.8e-30 104.6 7.7 3.0 2 1 1 3 3 3 2 Rab-GTPase-TBC domain PAPA-1 PF04795.7 CCH58871.1 - 2.8e-15 56.7 5.1 2.8e-15 56.7 3.5 3.3 3 1 1 4 4 4 1 PAPA-1-like conserved region PFEMP PF03011.10 CCH58871.1 - 6.9 7.0 17.7 8 6.7 2.1 2.3 2 0 0 2 2 2 0 PFEMP DBL domain Neugrin PF06413.6 CCH58873.1 - 1.5e-06 28.1 0.4 1.5e-06 28.1 0.3 2.0 1 1 1 2 2 2 1 Neugrin Mod_r PF07200.8 CCH58873.1 - 0.0004 20.3 0.3 0.0004 20.3 0.2 2.0 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein HTH_23 PF13384.1 CCH58873.1 - 0.063 12.9 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_11 PF08279.7 CCH58873.1 - 0.092 12.4 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.1 CCH58873.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF2697 PF10906.3 CCH58874.1 - 1.5e-25 89.0 0.7 1.7e-25 88.8 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) Y_phosphatase PF00102.22 CCH58875.1 - 4.6e-54 183.2 8.3 7.6e-53 179.2 5.7 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCH58875.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCH58875.1 - 0.0031 17.7 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CCH58875.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate SusD-like_3 PF14322.1 CCH58875.1 - 0.084 12.9 0.9 0.13 12.3 0.6 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane KH_3 PF13014.1 CCH58876.1 - 1.5e-06 27.6 0.1 3.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_1 PF00013.24 CCH58876.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CCH58876.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 KH domain HSP70 PF00012.15 CCH58877.1 - 4.8e-236 784.3 9.2 5.4e-236 784.2 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH58877.1 - 3.6e-16 58.6 0.4 1.4e-14 53.4 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCH58877.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2603 PF10788.4 CCH58877.1 - 0.063 13.0 0.0 0.24 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) Hom_end PF05204.9 CCH58878.1 - 1.4e-43 147.3 0.0 8.4e-37 125.5 0.0 2.4 2 0 0 2 2 2 2 Homing endonuclease Hom_end_hint PF05203.11 CCH58878.1 - 7.9e-39 133.6 0.0 9.3e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Hom_end-associated Hint LAGLIDADG_3 PF14528.1 CCH58878.1 - 2.1e-10 40.6 0.0 1.1e-05 25.6 0.0 3.1 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF1794 PF08768.6 CCH58878.1 - 0.1 12.4 0.2 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) ArfGap PF01412.13 CCH58879.1 - 9.7e-34 115.6 0.9 9.7e-34 115.6 0.6 3.9 4 1 1 5 5 5 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.1 CCH58880.1 - 3.4e-25 89.2 0.0 4.2e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCH58880.1 - 3.2e-17 62.9 0.0 4.6e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH58880.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 CCH58880.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SMK-1 PF04802.10 CCH58881.1 - 7.4e-45 152.8 27.3 1.1e-24 87.0 4.7 4.9 5 1 0 5 5 5 2 Component of IIS longevity pathway SMK-1 WH1 PF00568.18 CCH58881.1 - 0.026 14.2 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 WH1 domain Ras PF00071.17 CCH58882.1 - 1e-49 168.0 0.0 1.5e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH58882.1 - 3.4e-18 66.2 0.0 8.5e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH58882.1 - 3.5e-08 32.8 0.1 4.7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCH58882.1 - 2.6e-07 30.2 0.0 5.4e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCH58882.1 - 0.0031 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF605 PF04652.11 CCH58882.1 - 0.018 14.4 13.9 0.022 14.1 9.7 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 CCH58882.1 - 5.9 5.0 26.8 7.7 4.6 18.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Gly_transf_sug PF04488.10 CCH58883.1 - 7.3e-11 42.3 0.5 1.9e-10 41.0 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCH58883.1 - 0.017 13.6 0.5 0.041 12.3 0.0 1.8 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain K167R PF08065.7 CCH58884.1 - 0.0051 16.9 1.6 0.2 11.7 0.0 2.9 3 0 0 3 3 3 2 K167R (NUC007) repeat PIR PF00399.14 CCH58885.1 - 3.9e-26 89.4 47.8 2.2e-07 29.9 2.5 6.1 5 0 0 5 5 5 4 Yeast PIR protein repeat adh_short PF00106.20 CCH58886.1 - 1.2e-19 70.8 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH58886.1 - 1.2e-11 44.5 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCH58886.1 - 1.2e-05 25.2 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCH58886.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCH58886.1 - 0.063 13.2 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 CCH58887.1 - 2.9e-07 30.5 0.0 4.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CCH58887.1 - 0.1 12.5 0.0 0.36 10.7 0.0 1.8 2 1 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 CCH58888.1 - 1.8e-16 60.4 0.0 2.7e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH58888.1 - 4e-07 29.8 0.0 6.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCH58888.1 - 0.00038 20.3 0.0 0.00054 19.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCH58888.1 - 0.00064 19.2 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 CCH58888.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CCH58888.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding S-AdoMet_synt_C PF02773.11 CCH58889.1 - 4.1e-73 243.5 0.1 6.7e-73 242.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCH58889.1 - 7.2e-47 158.2 0.0 1.4e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCH58889.1 - 5.6e-44 148.4 0.1 1.2e-43 147.3 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PBP PF01161.15 CCH58890.1 - 7.1e-26 90.8 0.0 8.5e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3854 PF12965.2 CCH58890.1 - 0.13 11.9 0.2 1.6 8.4 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3854) PSP1 PF04468.7 CCH58891.1 - 2.7e-33 113.8 0.8 6e-33 112.6 0.5 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region zf-DHHC PF01529.15 CCH58892.1 - 1.4e-31 109.2 14.3 1.4e-31 109.2 9.9 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Pkinase PF00069.20 CCH58893.1 - 4.4e-71 239.0 0.0 4.4e-71 239.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58893.1 - 8.1e-40 136.5 1.8 1.1e-39 136.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.13 CCH58893.1 - 1.4e-33 114.6 0.3 8.1e-17 60.9 0.1 3.2 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CCH58893.1 - 2.2e-09 36.6 0.0 7.3e-08 31.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like SH3_3 PF08239.6 CCH58893.1 - 0.084 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain LMBR1 PF04791.11 CCH58893.1 - 0.46 8.9 5.7 0.68 8.4 3.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM60A PF15396.1 CCH58893.1 - 6.4 6.4 12.0 1.4e+02 2.0 0.0 2.5 2 0 0 2 2 2 0 Protein Family FAM60A SAP PF02037.22 CCH58894.1 - 2.2e-06 27.0 0.7 4.1e-06 26.1 0.5 1.5 1 0 0 1 1 1 1 SAP domain Chordopox_G3 PF06129.7 CCH58894.1 - 0.97 9.6 8.8 1.1 9.3 2.5 2.6 2 1 0 2 2 2 0 Chordopoxvirus G3 protein DUF2404 PF10296.4 CCH58895.1 - 0.00022 21.2 0.1 0.012 15.7 0.0 2.4 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) PX PF00787.19 CCH58896.1 - 5.6e-22 77.6 0.1 1.6e-21 76.2 0.1 1.8 1 0 0 1 1 1 1 PX domain TAF4 PF05236.9 CCH58897.1 - 9.5e-73 244.7 1.2 9.5e-73 244.7 0.8 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Suf PF05843.9 CCH58897.1 - 0.015 15.0 2.4 0.025 14.2 1.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PLA2_B PF01735.13 CCH58898.1 - 6.6e-213 707.3 2.8 6.6e-213 707.3 1.9 1.9 2 1 0 2 2 2 1 Lysophospholipase catalytic domain PLA2_B PF01735.13 CCH58899.1 - 5.2e-223 740.6 5.5 6.3e-223 740.3 3.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain zf-RING_2 PF13639.1 CCH58900.1 - 1.2e-12 47.3 4.7 2.2e-12 46.6 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCH58900.1 - 4.4e-11 42.7 4.5 7.6e-11 41.9 3.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCH58900.1 - 8.4e-09 34.9 4.8 1.4e-08 34.2 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH58900.1 - 2.5e-08 33.4 4.2 4.6e-08 32.6 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCH58900.1 - 1.2e-07 31.6 6.5 4.8e-07 29.7 4.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH58900.1 - 2e-07 30.5 7.5 4.6e-07 29.3 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH58900.1 - 3.8e-05 23.3 3.9 0.00016 21.2 2.7 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CCH58900.1 - 0.00073 19.3 4.4 0.0016 18.2 3.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 CCH58900.1 - 0.015 14.8 0.1 0.03 13.8 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NPV_P10 PF05531.7 CCH58900.1 - 0.026 14.7 0.9 0.026 14.7 0.7 2.6 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DASH_Hsk3 PF08227.6 CCH58900.1 - 0.067 13.3 0.3 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like zf-P11 PF03854.9 CCH58900.1 - 0.077 12.4 2.1 0.29 10.6 1.5 2.0 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 CCH58900.1 - 0.11 12.3 7.0 0.55 10.1 4.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4140 PF13600.1 CCH58900.1 - 0.17 12.3 0.1 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4041 PF13250.1 CCH58900.1 - 0.37 10.3 5.1 3.1 7.4 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) RINGv PF12906.2 CCH58900.1 - 0.61 10.1 5.7 1.7 8.7 4.0 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 CCH58900.1 - 2.2 7.9 6.1 7.3 6.2 4.2 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CCH58900.1 - 2.2 8.2 7.2 7.3 6.6 3.6 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain RNA_pol_I_TF PF04090.7 CCH58901.1 - 1e-50 171.8 9.6 2.6e-50 170.4 6.7 1.7 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor IncA PF04156.9 CCH58901.1 - 7.9 6.0 11.0 0.4 10.2 2.7 2.3 3 0 0 3 3 3 0 IncA protein Cpn60_TCP1 PF00118.19 CCH58902.1 - 1.1e-117 393.6 5.0 1.3e-117 393.3 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rubella_E2 PF05749.6 CCH58902.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 RRM_1 PF00076.17 CCH58904.1 - 5.7e-17 61.1 0.0 5.1e-16 58.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58904.1 - 3.3e-08 33.3 0.0 1.6e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BAF1_ABF1 PF04684.8 CCH58905.1 - 2.4 6.9 6.9 4.3 6.0 4.8 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TPR_8 PF13181.1 CCH58906.1 - 0.047 13.4 0.4 0.16 11.8 0.3 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Chitin_synth_1 PF01644.12 CCH58907.1 - 3e-76 254.7 0.3 6.4e-76 253.6 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCH58907.1 - 2.5e-24 84.7 0.7 8.1e-24 83.1 0.1 2.2 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCH58907.1 - 1.4e-20 73.2 10.9 4.7e-15 54.9 0.1 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCH58907.1 - 2e-11 44.0 0.5 6e-11 42.4 0.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCH58907.1 - 1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Tyr_Deacylase PF02580.11 CCH58908.1 - 2.1e-47 160.7 0.3 2.3e-47 160.6 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GATase_4 PF13230.1 CCH58909.1 - 4.4e-18 64.9 0.0 2.9e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCH58909.1 - 2.1e-10 40.6 0.0 4.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CCH58909.1 - 2.5e-08 33.0 0.0 1.1e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II DUF22 PF01629.11 CCH58909.1 - 0.096 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF22 GATase_7 PF13537.1 CCH58909.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain MARVEL PF01284.18 CCH58910.1 - 7.4e-20 71.2 8.4 9.9e-20 70.8 5.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain Mfp-3 PF04202.8 CCH58910.1 - 0.036 14.2 0.0 0.085 13.0 0.0 1.5 1 0 0 1 1 1 0 Foot protein 3 FA_desaturase PF00487.19 CCH58910.1 - 1.3 8.4 5.7 0.18 11.2 0.7 1.8 1 1 1 2 2 2 0 Fatty acid desaturase DUF3589 PF12141.3 CCH58911.1 - 3.7e-85 286.0 8.0 3.9e-53 180.4 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3589) DUF3589 PF12141.3 CCH58912.1 - 7.1e-99 331.3 8.2 2.3e-97 326.3 5.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF1776 PF08643.5 CCH58912.1 - 0.00087 18.5 4.4 0.42 9.6 3.2 2.4 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) DUF3589 PF12141.3 CCH58913.1 - 4.3e-91 305.6 10.9 9.6e-89 297.8 7.6 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF1700 PF08006.6 CCH58914.1 - 0.025 13.9 4.5 1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF1700 PF08006.6 CCH58915.1 - 0.0055 16.0 1.3 0.0055 16.0 0.9 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1700) PGG PF13962.1 CCH58915.1 - 0.011 15.3 1.7 0.063 12.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function Clc-like PF07062.7 CCH58915.1 - 0.014 14.6 8.3 0.017 14.3 0.4 2.1 2 0 0 2 2 2 0 Clc-like zf-LITAF-like PF10601.4 CCH58915.1 - 0.086 12.7 0.7 0.086 12.7 0.5 3.4 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DUF581 PF04570.9 CCH58915.1 - 0.12 11.6 0.1 0.12 11.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF581) DUF2207 PF09972.4 CCH58915.1 - 2.1 6.8 7.2 0.83 8.1 3.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Arm PF00514.18 CCH58916.1 - 2.6e-84 274.4 13.1 1.1e-12 47.2 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 CCH58916.1 - 2.5e-24 85.2 9.2 4.7e-24 84.3 6.4 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CCH58916.1 - 1.3e-18 67.0 0.0 3.7e-06 27.1 0.0 5.3 1 1 4 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 CCH58916.1 - 1.9e-17 63.1 0.4 0.00038 20.8 0.0 6.2 4 2 3 7 7 7 5 HEAT-like repeat Arm_2 PF04826.8 CCH58916.1 - 1.3e-07 31.0 2.5 0.0091 15.1 0.0 4.9 2 2 3 5 5 5 2 Armadillo-like HEAT PF02985.17 CCH58916.1 - 1.7e-07 30.7 0.1 2.6 8.3 0.0 7.0 8 0 0 8 8 8 2 HEAT repeat RICTOR_V PF14668.1 CCH58916.1 - 0.00012 21.9 3.7 1.9 8.4 0.0 5.3 3 3 4 7 7 7 2 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 CCH58916.1 - 0.00083 17.7 2.6 0.27 9.4 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit JAB PF01398.16 CCH58918.1 - 2.8e-27 94.7 0.1 5.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCH58918.1 - 8.6e-07 28.4 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCH58918.1 - 0.0032 16.9 0.5 0.0063 16.0 0.0 1.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0172) ELFV_dehydrog PF00208.16 CCH58919.1 - 1.2e-58 198.6 0.0 2.8e-58 197.3 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CCH58919.1 - 4.6e-19 67.4 0.1 3.1e-12 44.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 CCH58919.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.20 CCH58920.1 - 7.3e-55 185.9 0.0 1.1e-54 185.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH58920.1 - 3.6e-19 68.8 0.0 5.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH58920.1 - 1.9e-05 23.7 0.0 4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF116 PF01976.12 CCH58920.1 - 0.24 10.8 6.0 0.31 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF116 RRM_1 PF00076.17 CCH58921.1 - 4.9e-06 26.0 0.0 1.7e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58921.1 - 0.0036 17.2 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) XkdN PF08890.6 CCH58921.1 - 0.017 14.8 1.2 4.5 7.0 0.0 2.6 2 1 0 2 2 2 0 Phage XkdN-like protein TAF4 PF05236.9 CCH58921.1 - 4.6 6.4 12.6 0.025 13.8 0.7 2.1 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Ras PF00071.17 CCH58922.1 - 7.2e-42 142.5 0.0 1.2e-39 135.3 0.0 2.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CCH58922.1 - 5.1e-13 49.5 0.0 5.5e-12 46.2 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH58922.1 - 8.1e-05 21.9 0.0 0.36 10.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Hepar_II_III PF07940.8 CCH58922.1 - 0.00099 18.9 1.5 0.0017 18.1 1.0 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein DGF-1_C PF11040.3 CCH58922.1 - 0.45 10.4 5.7 5 7.0 2.7 2.6 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Macoilin PF09726.4 CCH58922.1 - 8 4.6 15.1 9.9 4.2 10.5 1.1 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 CCH58924.1 - 1.7e-26 91.6 0.3 7.6e-18 63.9 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH58924.1 - 3.7e-19 68.4 0.0 4.9e-11 42.4 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH58924.1 - 3.9e-12 45.8 0.1 2.2e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCH58924.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ctf8 PF09696.5 CCH58924.1 - 0.0035 17.1 0.2 0.017 14.8 0.1 2.2 2 0 0 2 2 2 1 Ctf8 Apc1 PF12859.2 CCH58926.1 - 1.7e-12 47.4 0.0 1.7e-12 47.4 0.0 3.0 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CCH58926.1 - 9.5e-05 22.4 5.1 0.75 10.1 0.1 4.3 3 0 0 3 3 3 2 Proteasome/cyclosome repeat Sugar_tr PF00083.19 CCH58927.1 - 2e-162 540.9 36.2 2.5e-162 540.5 25.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH58927.1 - 4.4e-34 117.7 32.8 1.2e-32 113.0 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH58927.1 - 9.9e-05 20.7 1.0 0.00024 19.4 0.7 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PS_Dcarbxylase PF02666.10 CCH58928.1 - 2.8e-76 255.3 0.0 4.1e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3422 PF11902.3 CCH58928.1 - 0.098 11.5 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Peptidase_M23 PF01551.17 CCH58928.1 - 0.17 11.9 0.3 32 4.6 0.0 3.0 2 1 1 3 3 3 0 Peptidase family M23 dCMP_cyt_deam_1 PF00383.17 CCH58929.1 - 3.2e-26 90.9 1.0 5e-26 90.3 0.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 CCH58929.1 - 0.015 14.9 0.2 0.026 14.2 0.2 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase FAA_hydrolase PF01557.13 CCH58930.1 - 8.6e-47 159.3 0.0 1.2e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DNA_RNApol_7kD PF03604.8 CCH58931.1 - 1.8e-16 59.3 1.7 2.3e-16 58.9 1.2 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 CCH58931.1 - 0.0021 17.8 0.6 0.0029 17.3 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2197 PF09963.4 CCH58931.1 - 0.0023 17.8 1.1 0.39 10.7 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.14 CCH58931.1 - 0.0027 17.3 0.2 0.0027 17.3 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 CCH58931.1 - 0.0033 17.1 0.9 0.0043 16.7 0.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 CCH58931.1 - 0.014 15.0 2.9 2.4 7.8 0.1 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) FYDLN_acid PF09538.5 CCH58931.1 - 0.02 15.4 0.5 0.024 15.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GFA PF04828.9 CCH58931.1 - 0.021 14.7 0.5 0.92 9.4 0.4 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme NCD3G PF07562.9 CCH58931.1 - 0.021 14.5 0.4 0.026 14.2 0.2 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_1 PF00130.17 CCH58931.1 - 0.029 14.0 0.5 0.04 13.6 0.4 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.11 CCH58931.1 - 0.037 13.9 0.4 0.039 13.8 0.3 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF4428 PF14471.1 CCH58931.1 - 0.053 13.2 1.9 0.9 9.3 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) A2L_zn_ribbon PF08792.5 CCH58931.1 - 0.058 12.8 0.9 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF2318 PF10080.4 CCH58931.1 - 0.058 13.1 0.2 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zinc-ribbons_6 PF07191.7 CCH58931.1 - 0.12 12.1 1.1 0.16 11.7 0.7 1.4 1 1 0 1 1 1 0 zinc-ribbons Ribosomal_L44 PF00935.14 CCH58931.1 - 0.14 12.1 4.2 3.1 7.8 0.1 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Zn_ribbon_recom PF13408.1 CCH58931.1 - 0.15 12.2 3.0 3.2 8.0 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L40e PF01020.12 CCH58931.1 - 0.21 11.1 2.3 0.27 10.8 1.6 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Gin PF10764.4 CCH58931.1 - 0.23 11.1 1.3 1.4 8.7 0.2 2.2 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin Zn-ribbon_8 PF09723.5 CCH58931.1 - 0.33 10.9 3.5 1 9.4 2.4 1.8 1 1 0 1 1 1 0 Zinc ribbon domain DUF2296 PF10058.4 CCH58931.1 - 0.37 10.5 2.2 0.53 10.0 0.1 1.9 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 CCH58931.1 - 0.38 10.1 2.3 10 5.5 0.1 2.1 1 1 2 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 CCH58931.1 - 0.59 9.9 3.2 3.7 7.4 2.6 1.8 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 CCH58931.1 - 1.1 8.9 3.5 6.7 6.3 2.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCH58931.1 - 1.2 8.8 3.6 8.4 6.1 2.5 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Chs3p PF12271.3 CCH58935.1 - 3.3e-92 308.5 22.5 1.6e-91 306.3 15.6 1.8 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit LHC PF00556.15 CCH58935.1 - 0.033 14.0 0.9 0.2 11.5 0.1 2.6 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2583 PF10762.4 CCH58935.1 - 1.1 9.4 10.1 0.55 10.4 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) Ribosomal_L44 PF00935.14 CCH58936.1 - 2.3e-34 117.2 11.1 3.5e-34 116.6 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Far-17a_AIG1 PF04750.9 CCH58937.1 - 5.4e-18 64.8 2.2 6.9e-18 64.5 1.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Homeobox_KN PF05920.6 CCH58938.1 - 0.25 11.0 2.3 0.31 10.7 0.1 2.4 2 0 0 2 2 2 0 Homeobox KN domain Ammonium_transp PF00909.16 CCH58939.1 - 1.7e-126 421.9 26.9 2e-126 421.6 18.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Prefoldin_2 PF01920.15 CCH58941.1 - 2.8e-18 65.6 12.6 3.3e-18 65.4 8.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit PspA_IM30 PF04012.7 CCH58941.1 - 0.00064 19.1 1.7 0.00087 18.7 1.2 1.2 1 0 0 1 1 1 1 PspA/IM30 family Baculo_PEP_C PF04513.7 CCH58941.1 - 0.021 14.6 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GCR PF02155.10 CCH58941.1 - 0.056 12.1 0.6 0.059 12.0 0.4 1.1 1 0 0 1 1 1 0 Glucocorticoid receptor TMF_DNA_bd PF12329.3 CCH58941.1 - 0.06 13.1 1.6 0.06 13.1 1.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rabaptin PF03528.10 CCH58941.1 - 0.082 12.8 11.6 0.22 11.4 0.9 2.2 1 1 1 2 2 2 0 Rabaptin FlaC_arch PF05377.6 CCH58941.1 - 0.085 12.7 0.5 0.085 12.7 0.3 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 CCH58941.1 - 0.089 13.2 2.8 0.13 12.7 0.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Prefoldin_3 PF13758.1 CCH58941.1 - 0.12 12.1 6.7 0.18 11.5 4.6 1.3 1 1 0 1 1 1 0 Prefoldin subunit Enkurin PF13864.1 CCH58941.1 - 0.2 11.8 8.9 3.1 8.0 1.9 2.4 2 1 0 2 2 2 0 Calmodulin-binding Prefoldin PF02996.12 CCH58941.1 - 0.2 11.2 6.9 1.4 8.6 5.0 2.0 1 1 0 1 1 1 0 Prefoldin subunit SPATA24 PF15175.1 CCH58941.1 - 0.23 11.1 5.8 0.31 10.7 4.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 HR1 PF02185.11 CCH58941.1 - 0.33 10.7 7.5 0.72 9.6 0.5 2.4 2 0 0 2 2 2 0 Hr1 repeat DivIC PF04977.10 CCH58941.1 - 0.34 10.4 12.0 0.14 11.6 0.5 2.3 1 1 1 2 2 2 0 Septum formation initiator MtrG PF04210.8 CCH58941.1 - 0.37 10.4 3.9 9.3 6.0 0.0 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Fib_alpha PF08702.5 CCH58941.1 - 0.53 10.3 6.8 0.62 10.1 2.8 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CCH58941.1 - 0.53 9.8 10.7 5.3 6.5 7.4 1.9 1 1 0 1 1 1 0 IncA protein SlyX PF04102.7 CCH58941.1 - 0.61 10.4 0.1 0.61 10.4 0.1 2.3 2 1 1 3 3 3 0 SlyX V_ATPase_I PF01496.14 CCH58941.1 - 0.74 7.5 5.8 0.89 7.3 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4600 PF15372.1 CCH58941.1 - 3.1 8.0 10.0 25 5.0 6.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) AAA_23 PF13476.1 CCH58941.1 - 3.2 8.0 10.6 4 7.6 7.4 1.1 1 0 0 1 1 1 0 AAA domain KID PF02524.9 CCH58941.1 - 4.4 7.8 8.1 7.7 7.1 0.1 3.7 3 0 0 3 3 3 0 KID repeat Aminotran_1_2 PF00155.16 CCH58942.1 - 3.7e-10 39.2 0.0 6.3e-10 38.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Fibrinogen_C PF00147.13 CCH58942.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain WLM PF08325.5 CCH58944.1 - 2e-47 161.4 0.4 2.7e-47 161.0 0.3 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 CCH58944.1 - 0.011 15.5 0.2 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Peptidase_MA_2 PF13485.1 CCH58944.1 - 0.038 14.0 0.1 0.059 13.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily SprT-like PF10263.4 CCH58944.1 - 0.091 12.4 0.5 0.14 11.7 0.3 1.4 1 1 0 1 1 1 0 SprT-like family INSIG PF07281.7 CCH58945.1 - 1.4e-14 53.8 3.8 2.3e-14 53.2 2.7 1.4 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) Endosulfine PF04667.12 CCH58946.1 - 8.1e-33 112.2 0.1 1e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_M14 PF00246.19 CCH58947.1 - 6e-64 216.3 0.0 7.4e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Menin PF05053.8 CCH58948.1 - 1.4 6.9 4.0 1.9 6.5 2.8 1.1 1 0 0 1 1 1 0 Menin Polysacc_synt_C PF14667.1 CCH58948.1 - 8.1 6.2 12.2 0.17 11.6 2.0 2.5 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Actin PF00022.14 CCH58950.1 - 6.9e-116 386.9 0.0 8e-116 386.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCH58950.1 - 0.049 12.2 0.0 6.6 5.2 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein UPRTase PF14681.1 CCH58951.1 - 1.2e-76 256.5 0.0 1.5e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCH58951.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 CCH58951.1 - 0.047 13.4 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) CoA_binding_2 PF13380.1 CCH58951.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain LSM PF01423.17 CCH58952.1 - 1.9e-18 65.7 0.2 2.7e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain RNA_pol_Rpc4 PF05132.9 CCH58952.1 - 0.12 12.3 1.2 0.15 12.0 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3984 PF13136.1 CCH58952.1 - 0.58 9.3 9.4 0.69 9.0 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Sox_N PF12444.3 CCH58952.1 - 4.8 8.3 7.1 4.1 8.5 3.2 1.9 2 0 0 2 2 2 0 Sox developmental protein N terminal CAP_GLY PF01302.20 CCH58953.1 - 5.2e-22 77.3 0.4 7.4e-22 76.8 0.3 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CCH58953.1 - 7.7e-08 32.4 0.1 7.7e-08 32.4 0.1 1.9 2 1 0 2 2 2 1 Ubiquitin-like domain L31 PF09784.4 CCH58953.1 - 0.11 12.5 0.5 0.19 11.8 0.3 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 SHOCT PF09851.4 CCH58953.1 - 0.29 10.6 0.2 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 Short C-terminal domain Choline_kinase PF01633.15 CCH58953.1 - 1 8.8 7.4 0.97 8.9 0.9 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase C2 PF00168.25 CCH58954.1 - 0.00022 21.0 0.0 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain CAP_N PF01213.14 CCH58956.1 - 1.5e-91 307.0 9.7 2.6e-91 306.1 6.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CCH58956.1 - 6.4e-58 194.5 1.5 1.4e-57 193.5 1.1 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CCH58956.1 - 0.0039 16.5 1.3 0.0091 15.3 0.9 1.6 1 0 0 1 1 1 1 Tubulin binding cofactor C S4 PF01479.20 CCH58957.1 - 3.6e-16 58.3 0.0 7.4e-16 57.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CCH58957.1 - 0.021 14.4 0.0 0.051 13.1 0.0 1.6 1 0 0 1 1 1 0 S4 domain GrpE PF01025.14 CCH58957.1 - 0.85 9.1 7.3 1.2 8.6 4.4 1.8 1 1 0 1 1 1 0 GrpE Eaf7 PF07904.8 CCH58958.1 - 1.3e-28 98.8 0.1 1.3e-28 98.8 0.1 3.2 4 0 0 4 4 4 1 Chromatin modification-related protein EAF7 DUF853 PF05872.7 CCH58959.1 - 0.11 10.7 2.5 0.16 10.2 1.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PP1c_bdg PF10488.4 CCH58959.1 - 0.12 11.5 9.1 0.16 11.1 6.3 1.1 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region SID-1_RNA_chan PF13965.1 CCH58959.1 - 0.62 8.1 2.9 0.66 8.0 2.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIP49_N PF14875.1 CCH58959.1 - 2.4 7.8 6.4 3.1 7.4 2.3 2.0 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 Mem_trans PF03547.13 CCH58959.1 - 4.5 5.4 5.7 6 5.0 4.0 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF912 PF06024.7 CCH58959.1 - 9.5 6.3 13.8 2.3e+02 1.9 9.6 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FKBP_C PF00254.23 CCH58960.1 - 6.2e-33 112.6 0.0 7.3e-33 112.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CDP-OH_P_transf PF01066.16 CCH58962.1 - 5.6e-14 52.2 6.9 5.6e-14 52.2 4.8 2.5 1 1 1 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF59 PF01883.14 CCH58963.1 - 0.00012 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 DSPc PF00782.15 CCH58964.1 - 7.7e-10 38.4 0.3 1.9e-09 37.1 0.2 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCH58964.1 - 8.2e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCH58964.1 - 0.0071 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CCH58964.1 - 0.064 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Gar1 PF04410.9 CCH58965.1 - 1.6e-40 138.0 2.8 1.6e-40 138.0 1.9 2.5 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Ribosomal_L35p PF01632.14 CCH58966.1 - 0.00093 19.0 4.0 0.0025 17.6 2.8 1.7 1 1 0 1 1 1 1 Ribosomal protein L35 CHCH PF06747.8 CCH58967.1 - 0.00014 21.7 2.0 0.00021 21.1 1.4 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CCH58967.1 - 0.0011 19.0 0.9 0.0016 18.4 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 RBDV_coat PF06593.6 CCH58967.1 - 0.096 11.8 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein UPF0203 PF05254.7 CCH58967.1 - 0.15 11.9 2.1 0.36 10.7 1.5 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Malate_synthase PF01274.17 CCH58968.1 - 6.1e-213 707.5 0.0 7.2e-213 707.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FHA PF00498.21 CCH58969.1 - 1.2e-15 57.3 0.9 3.8e-15 55.7 0.0 2.5 2 0 0 2 2 2 1 FHA domain zf-rbx1 PF12678.2 CCH58969.1 - 2.7e-06 27.3 4.8 5.5e-06 26.3 3.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCH58969.1 - 3.3e-06 26.8 10.6 5.7e-06 26.0 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 CCH58969.1 - 0.001 18.8 5.0 0.0023 17.7 3.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCH58969.1 - 0.0039 16.8 11.1 0.0073 15.9 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH58969.1 - 0.0089 15.7 8.9 0.015 15.0 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Sec_GG PF07549.9 CCH58969.1 - 0.096 11.9 0.6 0.27 10.5 0.4 1.8 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-C3HC4_2 PF13923.1 CCH58969.1 - 0.31 11.0 12.6 0.56 10.2 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CCH58969.1 - 0.65 10.0 5.5 1.3 9.0 3.8 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 CCH58969.1 - 2.1 8.1 6.8 3.8 7.2 4.7 1.4 1 0 0 1 1 1 0 PHD-finger DUF2417 PF10329.4 CCH58970.1 - 1.2e-53 181.8 15.1 1.8e-53 181.3 10.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 CCH58970.1 - 2.8e-13 50.2 0.0 3.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH58970.1 - 1.4e-10 41.0 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF912 PF06024.7 CCH58970.1 - 0.5 10.4 7.7 2.1 8.4 1.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-H2C2_2 PF13465.1 CCH58971.1 - 5.5e-21 73.7 31.9 4.3e-08 33.0 1.5 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCH58971.1 - 8.1e-20 69.9 32.3 1.1e-05 25.5 0.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH58971.1 - 2.6e-14 52.3 26.8 0.00064 19.8 0.4 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 CCH58971.1 - 0.00045 20.3 21.1 0.0053 16.9 0.5 4.9 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCH58971.1 - 0.01 15.9 7.7 0.051 13.7 0.5 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CCH58971.1 - 0.035 14.2 0.5 0.035 14.2 0.4 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CCH58971.1 - 1.5 8.6 23.4 0.55 10.0 0.5 3.7 3 1 1 4 4 4 0 BED zinc finger RNA_pol_L_2 PF13656.1 CCH58972.1 - 8.9e-30 101.9 0.0 1e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCH58972.1 - 7.8e-13 47.3 0.0 9.8e-13 47.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Maf PF02545.9 CCH58973.1 - 5.2e-36 123.5 0.0 6.4e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein F420_ligase PF01996.11 CCH58973.1 - 0.054 12.5 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase Cyt-b5 PF00173.23 CCH58974.1 - 1.4e-23 82.4 0.0 1.7e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain His_Phos_1 PF00300.17 CCH58975.1 - 4.6e-24 85.3 0.0 1.1e-23 84.0 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 CCH58975.1 - 3e-10 39.3 0.0 1.3e-09 37.3 0.0 2.2 1 0 0 1 1 1 1 TFIIIC subunit YEATS PF03366.11 CCH58976.1 - 8.6e-33 111.9 1.3 1.5e-32 111.1 0.9 1.4 1 0 0 1 1 1 1 YEATS family DUF382 PF04037.8 CCH58976.1 - 0.019 14.7 1.1 0.062 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF382) DUF3979 PF13141.1 CCH58976.1 - 0.11 12.3 3.4 1.2 9.0 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3979) ATP_bind_2 PF03668.10 CCH58976.1 - 0.12 11.4 1.4 1.6 7.7 0.3 2.0 1 1 1 2 2 2 0 P-loop ATPase protein family Syja_N PF02383.13 CCH58977.1 - 3.4e-84 282.3 1.5 3.4e-84 282.3 1.0 2.3 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 CCH58977.1 - 1.9e-25 90.2 0.0 4.1e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HMGL-like PF00682.14 CCH58978.1 - 2.3e-74 250.0 0.0 4.4e-74 249.1 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CCH58978.1 - 4.2e-22 78.3 0.1 8.5e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_S21 PF01165.15 CCH58978.1 - 0.15 11.5 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S21 DNA_pol_B PF00136.16 CCH58980.1 - 1.2e-111 373.8 9.0 1.2e-111 373.8 6.2 2.2 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CCH58980.1 - 1e-63 214.1 5.9 1e-63 214.1 4.1 2.6 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CCH58980.1 - 5.1e-44 150.4 0.5 2.3e-43 148.3 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CCH58980.1 - 7.6e-19 67.2 9.5 3.4e-18 65.2 6.6 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal zinc_ribbon_5 PF13719.1 CCH58980.1 - 0.068 12.7 0.8 15 5.2 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCH58980.1 - 0.12 12.0 1.2 15 5.4 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain ApoO PF09769.4 CCH58981.1 - 0.00018 21.2 1.4 0.025 14.2 0.1 2.2 2 0 0 2 2 2 2 Apolipoprotein O DNA_pol_B_3 PF08408.5 CCH58981.1 - 0.0064 16.3 0.8 0.011 15.6 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B viral insert Y_phosphatase2 PF03162.8 CCH58982.1 - 4.9e-56 188.6 0.0 6.2e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCH58982.1 - 2.7e-05 24.4 0.0 7.6e-05 23.0 0.0 1.6 1 1 1 2 2 2 1 Tyrosine phosphatase family DAD PF02109.11 CCH58983.1 - 2.9e-38 130.3 7.0 4.1e-38 129.9 4.8 1.2 1 0 0 1 1 1 1 DAD family LHH PF14411.1 CCH58983.1 - 0.23 11.6 1.6 0.34 11.1 1.1 1.2 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH DUF2721 PF11026.3 CCH58983.1 - 2 8.0 7.5 1.3 8.6 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) Ras PF00071.17 CCH58984.1 - 8.3e-44 148.8 0.2 1.5e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH58984.1 - 2.5e-14 53.7 0.1 2.5e-14 53.7 0.1 3.1 4 1 0 4 4 4 1 Miro-like protein Arf PF00025.16 CCH58984.1 - 5.8e-10 38.6 0.1 1.3e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCH58984.1 - 8e-06 25.8 1.1 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCH58984.1 - 0.00035 19.7 1.0 0.00092 18.4 0.7 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Hpr_kinase_C PF07475.7 CCH58984.1 - 0.13 11.5 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain zf-LITAF-like PF10601.4 CCH58985.1 - 0.041 13.7 3.3 0.096 12.5 2.3 1.6 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Mito_carr PF00153.22 CCH58986.1 - 7.9e-61 201.7 4.6 1.6e-21 75.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DNApol3-delta_C PF09115.5 CCH58986.1 - 0.06 13.3 0.3 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III, delta subunit, C terminal Glyco_transf_15 PF01793.11 CCH58987.1 - 1.1e-143 478.1 15.3 1.3e-143 477.8 10.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ABC2_membrane_4 PF12730.2 CCH58988.1 - 9.6e-05 21.6 1.7 0.00013 21.1 1.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein Ribosomal_S7e PF01251.13 CCH58989.1 - 1.8e-82 275.4 3.5 2.1e-82 275.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4265 PF14085.1 CCH58989.1 - 0.099 12.3 0.0 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) DUF692 PF05114.8 CCH58989.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Rib_5-P_isom_A PF06026.9 CCH58990.1 - 3.8e-54 182.5 0.0 4.9e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CCH58990.1 - 0.0078 15.8 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Arf PF00025.16 CCH58991.1 - 3.2e-72 241.4 0.6 3.6e-72 241.2 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCH58991.1 - 1.2e-15 57.1 0.0 1.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCH58991.1 - 3.4e-14 52.5 0.1 4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCH58991.1 - 1.7e-13 50.0 0.8 5.2e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCH58991.1 - 7.9e-11 41.5 0.0 9.4e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCH58991.1 - 1.4e-08 35.2 0.0 2.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCH58991.1 - 1.3e-06 28.2 0.1 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCH58991.1 - 0.074 12.1 0.3 0.15 11.0 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Imm11 PF15563.1 CCH58991.1 - 0.083 11.9 0.1 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 11 AMP-binding PF00501.23 CCH58992.1 - 4e-32 111.1 0.0 7e-14 51.0 0.0 4.6 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 CCH58992.1 - 1.1e-08 35.6 0.1 1.1e-08 35.6 0.1 3.1 3 0 0 3 3 3 1 DMAP1-binding Domain Mem_trans PF03547.13 CCH58993.1 - 1.5e-69 234.1 5.2 2e-69 233.7 3.6 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF2183 PF09949.4 CCH58994.1 - 1e-28 99.1 0.0 2.9e-28 97.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SDA1 PF05285.7 CCH58994.1 - 0.52 9.5 3.7 0.22 10.7 0.1 1.9 2 0 0 2 2 2 0 SDA1 zf-CCCH PF00642.19 CCH58995.1 - 0.0001 21.8 0.1 0.0001 21.8 0.1 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rap1-DNA-bind PF09197.5 CCH58995.1 - 0.031 14.8 1.2 0.062 13.8 0.1 2.1 2 1 0 2 2 2 0 Rap1, DNA-binding DUF2443 PF10398.4 CCH58995.1 - 0.056 13.2 0.5 0.16 11.8 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) zf-CCCH_2 PF14608.1 CCH58995.1 - 0.63 10.1 11.9 0.63 10.1 0.1 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Codanin-1_C PF15296.1 CCH58995.1 - 7.2 6.4 7.2 1.8 8.4 1.8 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus GSHPx PF00255.14 CCH58996.1 - 6.7e-46 154.1 0.2 9e-46 153.7 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCH58996.1 - 1.2e-05 24.9 0.1 2.6e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCH58996.1 - 5.6e-05 22.7 0.2 0.00014 21.4 0.1 1.7 1 1 0 1 1 1 1 Redoxin SlyX PF04102.7 CCH58997.1 - 0.034 14.5 0.7 0.081 13.3 0.5 1.6 1 0 0 1 1 1 0 SlyX BCDHK_Adom3 PF10436.4 CCH58998.1 - 1.1e-26 93.2 0.2 1.9e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCH58998.1 - 4.5e-14 52.0 0.0 1.2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCH58998.1 - 0.00024 20.7 0.0 0.022 14.4 0.0 2.2 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UCH_1 PF13423.1 CCH58998.1 - 0.057 12.8 0.4 0.085 12.2 0.3 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S18 PF01084.15 CCH58999.1 - 7.9e-16 57.6 0.1 2.6e-15 56.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 PhyH PF05721.8 CCH58999.1 - 0.099 12.6 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_6 PF00970.19 CCH59000.1 - 1.7e-16 60.1 0.0 3.3e-16 59.2 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCH59000.1 - 0.00025 21.5 0.0 0.00048 20.6 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain BAR_2 PF10455.4 CCH59001.1 - 7.1e-64 215.4 16.8 1e-63 214.9 11.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CCH59001.1 - 3.8e-12 46.2 11.7 2.3e-11 43.6 8.1 2.1 1 1 0 1 1 1 1 BAR domain Matrilin_ccoil PF10393.4 CCH59001.1 - 0.0038 16.5 1.3 0.018 14.4 0.2 2.4 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin E2R135 PF11570.3 CCH59001.1 - 0.99 9.4 9.5 1.5 8.9 5.2 2.2 1 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 DEAD PF00270.24 CCH59002.1 - 1.2e-45 155.0 0.1 7.9e-45 152.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 CCH59002.1 - 2e-20 72.3 4.5 2e-20 72.3 3.1 3.3 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 CCH59002.1 - 1e-19 70.1 0.0 2.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3449 PF11931.3 CCH59003.1 - 3.1e-28 98.6 0.0 7.4e-25 87.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 CCH59003.1 - 7.1e-10 38.7 3.6 0.00051 20.1 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCH59003.1 - 0.00095 19.2 0.3 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CCH59003.1 - 0.0026 17.8 7.2 0.073 13.2 1.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type SR-25 PF10500.4 CCH59003.1 - 3.4 7.0 7.8 6.4 6.1 5.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_Gly3P_dh_N PF01210.18 CCH59004.1 - 4.4e-52 175.9 0.0 8.3e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CCH59004.1 - 6e-48 162.3 0.0 1e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CCH59004.1 - 0.0014 19.0 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CCH59004.1 - 0.051 12.9 0.1 0.68 9.2 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Semialdhyde_dh PF01118.19 CCH59004.1 - 0.074 13.3 0.0 0.37 11.0 0.0 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Oxysterol_BP PF01237.13 CCH59005.1 - 7e-130 432.6 1.7 2.5e-129 430.7 0.1 2.4 2 1 0 2 2 2 1 Oxysterol-binding protein Ank PF00023.25 CCH59005.1 - 6.4e-14 50.9 0.0 4.7e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CCH59005.1 - 6.5e-12 44.4 0.0 4.7e-05 23.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CCH59005.1 - 7.5e-12 45.4 1.6 3.9e-05 23.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCH59005.1 - 5.5e-11 42.6 0.0 0.00046 20.6 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH_8 PF15409.1 CCH59005.1 - 8.2e-09 35.4 3.7 6.6e-08 32.5 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_5 PF13857.1 CCH59005.1 - 1.7e-08 34.3 3.5 0.0018 18.4 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.24 CCH59005.1 - 2.8e-08 33.8 0.1 2.8e-08 33.8 0.0 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 CCH59005.1 - 6.4e-05 23.1 0.4 6.4e-05 23.1 0.3 3.1 2 1 0 2 2 2 1 Pleckstrin homology domain Pkinase PF00069.20 CCH59006.1 - 6.3e-71 238.5 0.1 1.3e-70 237.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59006.1 - 2.5e-55 187.3 0.0 5e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59006.1 - 1.1e-06 27.7 0.0 8.2e-05 21.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SH3_1 PF00018.23 CCH59007.1 - 6.1e-09 35.1 0.0 1.6e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH59007.1 - 1.6e-05 24.3 0.1 4.4e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 CCH59008.1 - 4.1e-39 134.2 0.0 7.5e-23 80.9 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59008.1 - 6.3e-14 51.6 0.0 1.4e-09 37.4 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CCH59008.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCH59008.1 - 0.0059 15.6 0.1 11 4.9 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Steroid_dh PF02544.11 CCH59009.1 - 5e-31 107.4 11.5 1.2e-30 106.3 8.0 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase SAYSvFN PF10260.4 CCH59009.1 - 0.81 9.4 7.2 1.9 8.2 0.7 3.0 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Fibrillarin PF01269.12 CCH59010.1 - 1.4e-110 367.6 0.0 1.7e-110 367.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CCH59010.1 - 1.2e-05 24.9 0.1 2.1e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CCH59010.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CYSTM PF12734.2 CCH59011.1 - 4.3e-15 55.4 7.4 5e-15 55.2 5.1 1.1 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance Bac_rhodopsin PF01036.13 CCH59012.1 - 4.1e-50 170.1 17.6 4.7e-50 169.9 12.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1422 PF07226.6 CCH59012.1 - 0.82 9.4 7.2 0.17 11.6 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) DUF4131 PF13567.1 CCH59012.1 - 1.2 8.5 6.8 4 6.8 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Bac_rhodopsin PF01036.13 CCH59013.1 - 1.1e-48 165.4 17.5 1.3e-48 165.2 12.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein BRI3BP PF14965.1 CCH59013.1 - 0.0099 15.2 3.1 0.017 14.5 2.2 1.4 1 0 0 1 1 1 1 Negative regulator of p53/TP53 DUF4131 PF13567.1 CCH59013.1 - 0.011 15.0 10.6 0.046 13.1 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1422 PF07226.6 CCH59013.1 - 3.4 7.4 7.8 0.95 9.2 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) Bac_rhodopsin PF01036.13 CCH59014.1 - 2.4e-49 167.6 18.3 2.8e-49 167.4 12.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCH59014.1 - 1.8 7.9 8.7 0.92 8.8 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) BRI3BP PF14965.1 CCH59014.1 - 2.3 7.5 9.4 6.3 6.1 6.4 1.6 1 1 0 1 1 1 0 Negative regulator of p53/TP53 DUF1422 PF07226.6 CCH59014.1 - 2.6 7.8 9.5 0.27 10.9 2.1 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1422) Bac_rhodopsin PF01036.13 CCH59015.1 - 1.6e-48 164.9 17.9 1.8e-48 164.7 12.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCH59015.1 - 0.074 12.4 11.3 0.39 10.0 1.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Bac_rhodopsin PF01036.13 CCH59016.1 - 5.7e-48 163.1 16.1 6.6e-48 162.9 11.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein BRI3BP PF14965.1 CCH59016.1 - 0.43 9.9 8.1 0.29 10.4 4.0 1.7 1 1 1 2 2 2 0 Negative regulator of p53/TP53 DUF4131 PF13567.1 CCH59016.1 - 0.92 8.8 9.8 0.42 9.9 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ras PF00071.17 CCH59018.1 - 1e-56 190.7 0.4 1e-56 190.7 0.3 2.1 2 1 0 2 2 2 1 Ras family Miro PF08477.8 CCH59018.1 - 6.7e-21 74.9 0.1 1.6e-20 73.7 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH59018.1 - 1.3e-08 34.3 0.1 2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family ING PF12998.2 CCH59019.1 - 1.3e-12 47.8 0.1 2e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCH59019.1 - 3.8e-08 32.9 7.8 5.9e-08 32.2 5.4 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCH59019.1 - 0.08 13.0 2.3 0.16 12.1 1.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Glyco_transf_15 PF01793.11 CCH59020.1 - 1.2e-83 280.8 18.2 1.7e-83 280.3 12.6 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3139 PF11337.3 CCH59020.1 - 0.0027 17.9 3.9 0.0047 17.1 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3139) DUF1892 PF08987.5 CCH59020.1 - 0.045 13.7 0.4 0.14 12.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) DUF3753 PF12575.3 CCH59020.1 - 0.13 12.0 1.0 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Rib_5-P_isom_A PF06026.9 CCH59022.1 - 1.5e-53 180.6 0.1 1.9e-53 180.3 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CCH59022.1 - 0.00066 19.3 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain Mem_trans PF03547.13 CCH59023.1 - 7.4e-85 284.5 0.0 1.7e-84 283.3 0.0 1.6 1 1 0 1 1 1 1 Membrane transport protein Ras PF00071.17 CCH59024.1 - 4.9e-51 172.3 0.0 5.6e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH59024.1 - 2.7e-14 53.6 0.0 4.1e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH59024.1 - 2.9e-10 39.6 0.0 3.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CCH59024.1 - 0.00031 20.2 0.0 0.78 9.2 0.0 2.4 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CCH59024.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NST1 PF13945.1 CCH59025.1 - 3e-08 33.9 14.2 3e-08 33.9 9.8 9.0 6 2 2 8 8 8 1 Salt tolerance down-regulator Ras PF00071.17 CCH59026.1 - 5.6e-60 201.3 0.1 6.9e-60 201.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH59026.1 - 2.5e-20 73.1 0.0 3.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH59026.1 - 3.3e-18 65.5 0.0 3.9e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCH59026.1 - 6.8e-09 35.2 0.0 8.7e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH59026.1 - 3.7e-06 26.5 0.0 6.8e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCH59026.1 - 1.5e-05 24.9 0.0 2.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PP2C PF00481.16 CCH59027.1 - 6e-44 150.3 0.0 9.8e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C DUF846 PF05832.7 CCH59028.1 - 1.5e-46 157.6 6.7 1.9e-46 157.2 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Methyltransf_8 PF05148.10 CCH59029.1 - 6.2e-66 222.1 3.8 4.2e-64 216.1 0.4 2.8 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CCH59029.1 - 4.1e-08 33.6 2.5 7.3e-08 32.7 0.0 2.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH59029.1 - 5.9e-05 22.7 0.6 0.00026 20.6 0.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH59029.1 - 0.01 16.2 0.2 0.064 13.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCH59029.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CCH59029.1 - 0.32 10.3 3.1 0.91 8.8 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase small domain Hid1 PF12722.2 CCH59029.1 - 3.1 5.3 14.8 4.2 4.9 10.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 CCH59029.1 - 3.6 7.3 20.1 3.1 7.5 10.2 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Ndc1_Nup PF09531.5 CCH59029.1 - 4.1 5.7 10.6 5.3 5.3 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Clathrin PF00637.15 CCH59030.1 - 3.8e-23 81.6 9.4 5.7e-22 77.8 0.0 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS WD40 PF00400.27 CCH59030.1 - 1.3e-05 24.9 0.9 4e-05 23.3 0.6 1.9 1 0 0 1 1 1 1 WD domain, G-beta repeat CDC45 PF02724.9 CCH59030.1 - 0.0033 15.5 18.3 0.0053 14.8 12.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Vps39_1 PF10366.4 CCH59030.1 - 0.0048 16.8 1.4 0.066 13.2 0.0 3.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Nop14 PF04147.7 CCH59030.1 - 0.095 10.6 32.9 0.16 9.8 22.8 1.3 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 CCH59030.1 - 1.8 7.7 21.4 2.7 7.1 14.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 CCH59030.1 - 2.1 7.3 28.0 3.7 6.5 19.4 1.3 1 0 0 1 1 1 0 BUD22 Retinal PF15449.1 CCH59030.1 - 6.6 4.2 14.0 12 3.3 9.7 1.4 1 0 0 1 1 1 0 Retinal protein Tbf5 PF06331.7 CCH59031.1 - 6e-28 96.4 0.1 6.8e-28 96.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 RhoGAP PF00620.22 CCH59032.1 - 1.7e-37 128.3 0.0 6e-37 126.5 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CCH59032.1 - 1.3e-23 83.7 1.6 6e-23 81.5 0.4 2.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCH59032.1 - 1.5e-14 53.9 1.5 1.5e-14 53.9 1.1 4.6 4 1 0 4 4 4 1 RasGEF N-terminal motif 60KD_IMP PF02096.15 CCH59033.1 - 6.1e-37 127.2 2.3 6.1e-37 127.2 1.6 2.2 2 0 0 2 2 2 1 60Kd inner membrane protein Tweety PF04906.8 CCH59033.1 - 0.072 11.4 0.0 0.14 10.5 0.0 1.4 1 0 0 1 1 1 0 Tweety PET122 PF05476.6 CCH59034.1 - 4.8e-49 167.0 1.8 5.9e-49 166.7 1.3 1.0 1 0 0 1 1 1 1 PET122 SWIM PF04434.12 CCH59035.1 - 0.015 14.7 4.0 0.12 11.8 0.1 2.4 2 0 0 2 2 2 0 SWIM zinc finger UCH PF00443.24 CCH59036.1 - 5.1e-50 170.0 12.4 5.1e-50 170.0 8.6 2.9 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Xpo1 PF08389.7 CCH59037.1 - 1.1e-34 119.4 0.3 1.1e-34 119.4 0.2 4.8 6 0 0 6 6 6 1 Exportin 1-like protein AAA PF00004.24 CCH59038.1 - 2.6e-16 60.0 0.1 9.3e-16 58.2 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCH59038.1 - 1.1e-13 51.2 2.3 2.4e-13 50.0 0.2 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CCH59038.1 - 2.9e-12 46.3 0.1 7e-12 45.1 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CCH59038.1 - 1.2e-09 37.3 1.4 3e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CCH59038.1 - 3.8e-06 26.1 0.0 1.2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCH59038.1 - 6e-06 26.4 0.0 6.3e-05 23.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCH59038.1 - 6.7e-06 25.8 0.1 1.6e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCH59038.1 - 2.5e-05 24.1 1.3 4.4e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH59038.1 - 0.00027 20.6 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CCH59038.1 - 0.00064 18.7 0.0 0.0013 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCH59038.1 - 0.0015 18.5 0.0 0.027 14.4 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CCH59038.1 - 0.0031 16.7 0.0 0.083 12.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCH59038.1 - 0.0033 17.0 0.8 0.013 15.0 0.5 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CCH59038.1 - 0.008 15.1 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 CCH59038.1 - 0.009 14.8 0.1 0.22 10.2 0.0 2.5 1 1 2 3 3 3 1 SNF2 family N-terminal domain Arch_ATPase PF01637.13 CCH59038.1 - 0.017 14.8 0.4 0.62 9.7 0.3 2.4 1 1 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 CCH59038.1 - 0.017 14.9 0.6 0.19 11.5 0.0 2.6 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 CCH59038.1 - 0.018 14.4 0.1 0.17 11.3 0.1 2.5 1 1 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 CCH59038.1 - 0.023 15.5 0.0 0.076 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCH59038.1 - 0.024 14.2 0.0 0.066 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCH59038.1 - 0.027 14.2 0.2 0.4 10.3 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CCH59038.1 - 0.04 14.2 8.1 0.16 12.2 5.6 2.0 1 1 0 1 1 1 0 AAA domain PE-PPE PF08237.6 CCH59038.1 - 0.06 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DEAD PF00270.24 CCH59038.1 - 0.079 12.4 0.1 1.2 8.5 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 CCH59038.1 - 0.084 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 CCH59038.1 - 0.16 11.3 0.0 0.58 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Yae1_N PF09811.4 CCH59039.1 - 2.9e-12 45.8 0.1 3.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal P5CR_dimer PF14748.1 CCH59039.1 - 0.031 14.2 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation DUF1183 PF06682.7 CCH59039.1 - 0.052 13.1 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) CN_hydrolase PF00795.17 CCH59040.1 - 6.8e-09 35.3 0.0 1.2e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4458 PF14660.1 CCH59040.1 - 0.06 13.3 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4458) LicD PF04991.8 CCH59041.1 - 5.9e-39 134.3 5.3 5.9e-39 134.3 3.7 4.2 4 0 0 4 4 4 1 LicD family Pkinase PF00069.20 CCH59042.1 - 1e-42 146.1 0.0 1.9e-42 145.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59042.1 - 1.1e-17 63.9 0.0 2.1e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH59042.1 - 0.0011 18.7 0.1 0.002 17.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCH59042.1 - 0.0032 16.5 0.0 0.007 15.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCH59042.1 - 0.004 16.1 0.0 0.0075 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CCH59042.1 - 0.0051 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 RIO1 family AAA PF00004.24 CCH59043.1 - 3.5e-51 172.8 0.0 1.1e-42 145.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CCH59043.1 - 2e-19 69.3 0.6 5.8e-19 67.9 0.4 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_17 PF13207.1 CCH59043.1 - 2.3e-09 38.0 0.5 0.0033 18.2 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CCH59043.1 - 5.6e-07 29.5 5.7 0.014 15.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 CCH59043.1 - 4.6e-06 26.9 0.2 0.044 14.0 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CCH59043.1 - 6.3e-06 26.3 3.1 0.033 14.3 0.1 4.3 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CCH59043.1 - 7.2e-06 26.1 0.0 0.0011 19.0 0.0 2.8 2 2 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 CCH59043.1 - 8e-05 22.7 0.2 0.11 12.6 0.0 3.7 3 0 0 3 3 3 1 RNA helicase RuvB_N PF05496.7 CCH59043.1 - 0.00011 21.2 0.0 0.0023 17.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCH59043.1 - 0.00028 20.3 0.0 0.2 11.0 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein NACHT PF05729.7 CCH59043.1 - 0.00045 19.9 1.2 1.7 8.3 0.0 3.5 3 1 0 3 3 3 2 NACHT domain AAA_28 PF13521.1 CCH59043.1 - 0.00051 20.0 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CCH59043.1 - 0.00052 19.9 0.0 0.051 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 CCH59043.1 - 0.0017 18.1 0.2 3.1 7.4 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_33 PF13671.1 CCH59043.1 - 0.0017 18.2 0.0 0.023 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCH59043.1 - 0.0023 17.5 0.0 0.31 10.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCH59043.1 - 0.0091 15.4 0.3 4.9 6.5 0.0 3.6 2 2 1 4 4 4 1 AAA domain TIP49 PF06068.8 CCH59043.1 - 0.0098 14.6 0.2 0.027 13.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus ABC_tran PF00005.22 CCH59043.1 - 0.0098 16.1 0.1 1.9 8.8 0.0 3.3 2 2 1 3 3 3 1 ABC transporter AAA_5 PF07728.9 CCH59043.1 - 0.01 15.5 0.0 0.11 12.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 CCH59043.1 - 0.02 14.4 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zot PF05707.7 CCH59043.1 - 0.021 14.3 0.1 0.19 11.2 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 CCH59043.1 - 0.021 14.2 0.0 4.6 6.5 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 CCH59043.1 - 0.03 13.3 0.1 4.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 CCH59043.1 - 0.036 13.1 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CCH59043.1 - 0.076 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Clat_adaptor_s PF01217.15 CCH59044.1 - 6.6e-53 178.2 5.5 7.4e-53 178.0 3.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pox_A6 PF04924.7 CCH59044.1 - 0.013 14.3 0.3 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A6 protein DUF4588 PF15251.1 CCH59045.1 - 2e-10 41.0 5.0 3.7e-10 40.2 3.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.8 CCH59045.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Hairy Orange SUR7 PF06687.7 CCH59046.1 - 1.3e-22 80.3 10.4 2.3e-22 79.6 7.2 1.3 1 0 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.11 CCH59046.1 - 0.0011 17.7 6.0 0.002 16.8 4.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3328 PF11807.3 CCH59046.1 - 4.3 6.9 7.0 0.27 10.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) GFO_IDH_MocA PF01408.17 CCH59047.1 - 1.3e-05 25.6 0.0 1.9e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCH59047.1 - 0.0072 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Suc_Fer-like PF06999.7 CCH59048.1 - 1.3e-34 120.2 0.2 1.7e-34 119.8 0.1 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Gsf2 PF11055.3 CCH59049.1 - 1.3e-134 448.4 0.3 1.4e-134 448.3 0.2 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 BUD22 PF09073.5 CCH59052.1 - 0.015 14.4 20.9 0.022 13.8 14.5 1.2 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.5 CCH59052.1 - 0.13 11.4 23.1 0.18 10.9 16.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 LRR_6 PF13516.1 CCH59052.1 - 3.6 7.9 20.0 5.4 7.3 0.1 8.3 9 1 0 9 9 9 0 Leucine Rich repeat Peptidase_S49_N PF08496.5 CCH59052.1 - 8.7 6.1 11.9 5.6 6.7 1.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FAD_binding_2 PF00890.19 CCH59053.1 - 6.7e-74 249.2 0.0 7.6e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCH59053.1 - 4.2e-07 29.2 0.0 6.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCH59053.1 - 7.1e-07 29.1 0.0 9.7e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCH59053.1 - 6.2e-06 25.4 0.2 6.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CCH59053.1 - 1.8e-05 24.7 0.1 0.00032 20.6 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH59053.1 - 0.00033 20.7 0.0 0.0033 17.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCH59053.1 - 0.0013 17.3 2.6 0.049 12.0 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 CCH59053.1 - 0.0022 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCH59053.1 - 0.0033 16.4 0.1 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 CCH59053.1 - 0.033 13.0 2.9 0.045 12.6 0.1 2.5 3 1 1 4 4 4 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CCH59053.1 - 0.039 13.7 0.0 0.088 12.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 CCH59053.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 CCH59053.1 - 0.23 10.4 0.1 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Isy1 PF06246.7 CCH59054.1 - 7.6e-26 91.0 11.8 8.6e-26 90.8 8.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF515 PF04415.7 CCH59054.1 - 0.017 13.3 4.9 0.019 13.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FliD_N PF02465.13 CCH59054.1 - 0.044 14.1 0.4 0.044 14.1 0.3 1.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.17 CCH59054.1 - 0.14 12.1 5.1 0.36 10.8 3.1 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V-SNARE PF05008.10 CCH59054.1 - 2.8 8.1 6.3 1.6 8.9 0.1 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF2175 PF09943.4 CCH59054.1 - 7.3 6.7 7.9 2.7 8.1 1.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Oxidored_FMN PF00724.15 CCH59055.1 - 1.5e-118 395.6 0.0 1.8e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GDA1_CD39 PF01150.12 CCH59056.1 - 1.1e-19 70.3 0.0 1.6e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NAD_kinase PF01513.16 CCH59057.1 - 8.2e-65 218.3 0.0 1.5e-64 217.5 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase UBA PF00627.26 CCH59058.1 - 1.4e-22 78.8 3.8 2.1e-13 49.6 0.3 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 CCH59058.1 - 1.6e-14 53.1 0.6 1.6e-14 53.1 0.4 2.0 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.18 CCH59058.1 - 1.7e-14 52.9 0.6 1.9e-13 49.6 0.6 2.2 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CCH59058.1 - 8.4e-06 25.3 0.8 2.3e-05 24.0 0.6 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CCH59058.1 - 0.0056 16.5 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 CCH59058.1 - 0.042 13.3 0.2 8.5 5.9 0.0 3.9 4 0 0 4 4 4 0 CUE domain RepB PF07506.6 CCH59058.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 RepB plasmid partitioning protein DUF2407 PF10302.4 CCH59058.1 - 0.085 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Anp1 PF03452.9 CCH59059.1 - 2.2e-122 407.3 0.0 4.4e-122 406.4 0.0 1.5 1 0 0 1 1 1 1 Anp1 AAR2 PF05282.6 CCH59059.1 - 0.0053 15.7 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein DUF3752 PF12572.3 CCH59059.1 - 2.3 8.3 14.9 0.063 13.4 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) PAT1 PF09770.4 CCH59059.1 - 5.3 5.1 36.6 7.5 4.6 25.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-5a PF01287.15 CCH59060.1 - 2.1e-27 94.8 0.2 3e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCH59060.1 - 0.00014 21.4 0.3 0.00024 20.6 0.2 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCH59060.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain MCM PF00493.18 CCH59061.1 - 2.2e-128 427.7 0.1 3.5e-128 427.0 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCH59061.1 - 1.5e-19 70.6 0.0 6.7e-19 68.5 0.0 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCH59061.1 - 1.2e-07 31.1 0.0 1.3e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCH59061.1 - 0.0035 16.9 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCH59061.1 - 0.0046 16.4 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Hydrolase PF00702.21 CCH59062.1 - 1e-22 81.6 0.0 3e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH59062.1 - 1.6e-22 80.6 0.1 2.9e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCH59062.1 - 2.5e-17 62.6 0.2 6.5e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCH59062.1 - 4.1e-07 29.8 0.0 1.4e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCH59062.1 - 0.00028 20.5 1.0 0.0021 17.7 0.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CCH59062.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase HSP70 PF00012.15 CCH59063.1 - 1.2e-265 882.1 15.1 1.4e-265 881.9 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH59063.1 - 2.1e-15 56.1 1.8 9.9e-13 47.3 0.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCH59063.1 - 0.00036 20.2 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CCH59063.1 - 0.0044 16.3 0.0 0.031 13.5 0.0 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 CCH59063.1 - 0.045 13.5 12.8 0.72 9.6 0.9 4.7 3 2 0 3 3 3 0 Cell division protein FtsA DUF2797 PF10977.3 CCH59063.1 - 0.2 11.2 4.0 0.39 10.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DUF4473 PF14747.1 CCH59063.1 - 0.25 11.5 9.7 7.3 6.8 2.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4473) Hydantoinase_A PF01968.13 CCH59063.1 - 0.37 9.8 9.5 0.24 10.4 0.1 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Spectrin PF00435.16 CCH59063.1 - 3.3 8.0 10.2 9.9 6.5 7.1 1.8 1 1 0 1 1 1 0 Spectrin repeat CoA_binding PF02629.14 CCH59064.1 - 2.1e-24 85.8 1.9 2.3e-23 82.4 0.1 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CCH59064.1 - 2.8e-21 75.7 0.1 5.3e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CCH59064.1 - 6e-08 32.3 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CCH59064.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain UBA PF00627.26 CCH59065.1 - 7.2e-11 41.5 0.5 1.9e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.11 CCH59065.1 - 0.00084 18.7 0.6 0.0028 17.1 0.0 2.3 2 1 0 2 2 2 1 CUE domain UBA_4 PF14555.1 CCH59065.1 - 0.0037 16.7 0.0 0.009 15.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Iso_dh PF00180.15 CCH59066.1 - 4.5e-100 334.9 0.0 5.1e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 CCH59066.1 - 0.034 13.3 0.1 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthetic protein PdxA Ribosomal_L18e PF00828.14 CCH59067.1 - 3.5e-22 79.1 8.2 3.7e-22 79.0 3.7 2.3 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 CPL PF08144.6 CCH59070.1 - 4.3e-17 62.3 2.9 1.6e-16 60.4 0.1 3.1 4 0 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 CCH59070.1 - 8.9e-10 37.5 2.2 0.13 11.7 0.0 6.6 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat FANCI_S2 PF14676.1 CCH59070.1 - 0.047 13.5 4.3 0.068 13.0 1.1 2.8 2 2 0 2 2 2 0 FANCI solenoid 2 DUF3385 PF11865.3 CCH59070.1 - 0.4 10.5 3.7 0.29 11.0 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Daxx PF03344.10 CCH59070.1 - 0.82 8.0 20.0 1.1 7.6 13.9 1.1 1 0 0 1 1 1 0 Daxx Family HlyIII PF03006.15 CCH59071.1 - 7.6e-47 159.5 19.8 1.1e-46 159.0 13.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF3493 PF11998.3 CCH59071.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DUF613 PF04764.7 CCH59071.1 - 0.14 12.1 1.2 14 5.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF613) SLA_LP_auto_ag PF05889.8 CCH59071.1 - 0.16 10.4 0.2 0.23 9.8 0.2 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Draxin PF15550.1 CCH59072.1 - 0.0064 16.1 0.0 0.0075 15.9 0.0 1.0 1 0 0 1 1 1 1 Draxin Pkinase PF00069.20 CCH59073.1 - 8.8e-54 182.3 0.0 7.7e-52 176.0 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59073.1 - 5.5e-27 94.4 0.0 3.6e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59073.1 - 0.00015 20.8 0.0 0.0003 19.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH59073.1 - 0.00096 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH59073.1 - 0.0054 16.5 4.1 1.3 8.7 0.3 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family tRNA-synt_1b PF00579.20 CCH59074.1 - 3e-20 72.5 0.0 4.8e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Methyltransf_23 PF13489.1 CCH59075.1 - 9.1e-23 80.7 0.0 1.3e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH59075.1 - 2.7e-18 66.0 0.0 4.7e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH59075.1 - 1.9e-16 60.2 0.0 4e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH59075.1 - 2.3e-13 50.4 0.0 5e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH59075.1 - 4.4e-13 49.7 0.0 1e-12 48.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH59075.1 - 1e-08 35.4 0.0 2.8e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CCH59075.1 - 7.6e-08 31.7 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 CCH59075.1 - 9.7e-07 28.1 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCH59075.1 - 1.3e-06 27.8 0.0 2.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 CCH59075.1 - 1.6e-05 24.3 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 CCH59075.1 - 2.6e-05 24.2 0.0 8.7e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH59075.1 - 7.3e-05 21.9 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 CCH59075.1 - 8.7e-05 21.5 0.0 0.00019 20.4 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase MetW PF07021.7 CCH59075.1 - 0.0002 20.7 0.0 0.00087 18.7 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CCH59075.1 - 0.00081 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCH59075.1 - 0.0018 17.0 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_LP_H2 PF03356.10 CCH59075.1 - 0.0028 17.3 0.1 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Viral late protein H2 Methyltransf_4 PF02390.12 CCH59075.1 - 0.0044 16.1 0.0 0.17 10.9 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 CCH59075.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 CCH59075.1 - 0.042 13.0 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FmrO PF07091.6 CCH59075.1 - 0.089 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 CCH59075.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UvrD_C PF13361.1 CCH59076.1 - 2.8e-37 128.9 7.7 2.8e-37 128.9 5.3 2.7 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCH59076.1 - 9e-31 107.3 13.5 1.2e-27 97.0 3.7 3.1 2 2 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 CCH59076.1 - 1.6e-10 40.9 0.0 0.0005 19.6 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CCH59076.1 - 1.2e-09 38.2 0.0 6.9e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCH59076.1 - 4e-08 32.8 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CCH59076.1 - 4.4e-05 23.1 1.4 4.4e-05 23.1 1.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCH59076.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Vps52 PF04129.7 CCH59077.1 - 1.9e-141 472.0 22.4 2.6e-141 471.6 15.5 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Baculo_PEP_C PF04513.7 CCH59077.1 - 0.19 11.5 7.3 0.08 12.7 1.6 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 CCH59077.1 - 0.93 9.2 9.2 3.9 7.2 1.3 3.0 2 1 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 CCH59077.1 - 6.2 6.9 12.9 3.3 7.8 0.5 3.9 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family tRNA_m1G_MT PF01746.16 CCH59078.1 - 2.9e-37 128.0 0.4 5.5e-37 127.1 0.3 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Reo_sigmaC PF04582.7 CCH59079.1 - 0.96 8.5 9.8 0.22 10.6 1.1 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein MutS_V PF00488.16 CCH59080.1 - 4.8e-99 330.5 0.1 9.7e-99 329.5 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCH59080.1 - 1.4e-36 126.2 0.5 1.4e-35 122.9 0.0 2.6 2 1 1 3 3 3 1 MutS domain III MutS_II PF05188.12 CCH59080.1 - 1.3e-20 73.8 2.1 1.4e-20 73.7 0.1 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 CCH59080.1 - 2e-18 66.3 2.1 2e-18 66.3 1.4 3.0 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 CCH59080.1 - 1.3e-10 41.3 0.1 8.3e-10 38.6 0.0 2.4 3 0 0 3 3 3 1 MutS domain I Hist_deacetyl PF00850.14 CCH59081.1 - 7.1e-63 212.7 0.2 6.7e-62 209.5 0.2 2.0 1 1 0 1 1 1 1 Histone deacetylase domain EF-hand_1 PF00036.27 CCH59082.1 - 4.2e-28 94.4 5.3 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CCH59082.1 - 2.1e-25 88.6 0.9 2.7e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCH59082.1 - 1.2e-23 80.7 3.9 6.3e-08 31.8 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CCH59082.1 - 3.5e-19 67.2 2.3 1.9e-07 30.1 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CCH59082.1 - 1e-17 63.4 5.1 5.5e-10 38.6 0.0 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 CCH59082.1 - 6.8e-13 48.3 0.0 3.7e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 CCH59082.1 - 2.1e-05 24.0 0.0 0.13 11.8 0.0 2.8 2 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 CCH59082.1 - 6.1e-05 23.0 0.1 0.023 14.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 CCH59082.1 - 0.0026 17.3 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein DUF853 PF05872.7 CCH59082.1 - 0.011 14.1 0.4 0.062 11.6 0.1 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) p25-alpha PF05517.7 CCH59082.1 - 0.012 15.8 0.0 0.17 12.0 0.0 2.0 1 1 1 2 2 2 0 p25-alpha EF-hand_4 PF12763.2 CCH59082.1 - 0.015 15.0 1.5 0.042 13.5 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 CCH59082.1 - 0.017 14.8 0.1 0.47 10.1 0.0 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TerB PepSY_2 PF13670.1 CCH59082.1 - 0.062 13.2 0.0 3.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain RNA_pol_Rpb4 PF03874.11 CCH59082.1 - 0.082 12.9 1.1 0.49 10.4 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 LNS2 PF08235.8 CCH59082.1 - 0.13 11.8 0.0 1.5 8.3 0.0 2.0 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DnaJ PF00226.26 CCH59084.1 - 3e-06 26.8 0.6 5.8e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Sensor_TM1 PF13755.1 CCH59084.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain CM_2 PF01817.16 CCH59085.1 - 2.3e-08 34.0 0.0 0.0037 17.3 0.0 3.7 2 1 0 2 2 2 2 Chorismate mutase type II Baculo_FP PF03258.9 CCH59085.1 - 0.016 14.3 0.6 0.016 14.3 0.4 1.9 2 0 0 2 2 2 0 Baculovirus FP protein Mito_carr PF00153.22 CCH59086.1 - 4.4e-62 205.8 2.8 1.3e-20 72.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SIP1 PF04938.7 CCH59087.1 - 0.00018 20.9 2.4 0.00058 19.2 0.8 2.3 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) RSS_P20 PF11757.3 CCH59087.1 - 0.19 11.8 1.5 0.28 11.3 0.2 1.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like Tfb4 PF03850.9 CCH59089.1 - 4.3e-103 344.3 3.9 4.9e-103 344.1 2.7 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 CCH59089.1 - 0.0054 16.8 0.0 0.0079 16.3 0.0 1.3 1 1 0 1 1 1 1 von Willebrand factor type A domain WD40 PF00400.27 CCH59090.1 - 1.7e-11 43.4 7.5 0.048 13.5 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 CCH59090.1 - 4.8e-06 26.1 0.1 8.4e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 LisH Packaging_FI PF14000.1 CCH59090.1 - 0.23 11.6 12.7 0.64 10.2 0.2 3.2 2 1 1 3 3 3 0 DNA packaging protein FI Vps51 PF08700.6 CCH59091.1 - 3e-07 30.2 5.0 3e-07 30.2 3.4 2.9 3 0 0 3 3 3 1 Vps51/Vps67 Fes1 PF08609.5 CCH59092.1 - 1.6e-22 79.7 1.8 1.6e-22 79.7 1.3 2.2 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 CDC14 PF08045.6 CCH59092.1 - 1.5e-07 30.8 8.1 1.5e-07 30.8 5.6 1.9 1 1 0 2 2 2 1 Cell division control protein 14, SIN component HEAT_2 PF13646.1 CCH59092.1 - 0.00068 19.8 0.0 0.039 14.2 0.0 2.5 1 1 0 2 2 2 1 HEAT repeats V-ATPase_H_C PF11698.3 CCH59092.1 - 0.0055 16.6 2.3 0.013 15.4 1.2 2.0 2 0 0 2 2 2 1 V-ATPase subunit H Telomere_reg-2 PF10193.4 CCH59092.1 - 7.8 6.7 8.2 3.1 8.1 0.5 3.0 2 1 0 3 3 3 0 Telomere length regulation protein ERCC4 PF02732.10 CCH59093.1 - 1.6e-05 24.7 8.9 1.6e-05 24.7 6.2 2.4 1 1 1 2 2 2 1 ERCC4 domain Sec8_exocyst PF04048.9 CCH59094.1 - 6.3e-33 113.3 15.6 1.7e-32 112.0 2.4 3.5 3 0 0 3 3 3 2 Sec8 exocyst complex component specific domain 4HBT_2 PF13279.1 CCH59095.1 - 1.7e-10 41.4 0.0 2.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily TTL PF03133.10 CCH59096.1 - 3.1e-78 262.6 6.3 5.1e-78 261.9 4.4 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 CCH59096.1 - 2.3e-37 128.2 0.0 4.2e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 CCH59096.1 - 0.00049 18.9 0.0 0.026 13.3 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CCH59096.1 - 0.0019 17.9 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCH59096.1 - 0.0062 15.3 0.0 0.019 13.7 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RhoGAP PF00620.22 CCH59096.1 - 0.066 12.8 0.7 1.7 8.2 0.1 2.5 2 0 0 2 2 2 0 RhoGAP domain zf-Tim10_DDP PF02953.10 CCH59097.1 - 1.4e-14 53.1 0.6 1.8e-14 52.7 0.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PCNA_N PF00705.13 CCH59098.1 - 1.4e-51 173.2 1.8 4.7e-51 171.5 1.1 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CCH59098.1 - 7.6e-45 151.9 0.2 1.4e-44 151.0 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 CCH59098.1 - 2.2e-05 23.3 0.0 0.00067 18.5 0.0 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CCH59098.1 - 0.0095 15.0 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Rad9 Acetyltransf_1 PF00583.19 CCH59099.1 - 1e-19 70.3 0.0 1.5e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCH59099.1 - 1e-10 41.6 0.0 1.6e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCH59099.1 - 1.1e-10 41.6 0.0 1.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCH59099.1 - 4.2e-09 36.0 0.0 6.5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CCH59099.1 - 2.6e-08 34.1 0.0 3.3e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCH59099.1 - 5.8e-08 32.8 0.0 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCH59099.1 - 1.1e-05 25.2 0.0 2.6e-05 24.1 0.0 1.5 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCH59099.1 - 0.0023 17.8 0.0 0.017 14.9 0.0 2.5 2 1 0 2 2 2 1 GCN5-related N-acetyl-transferase DUF4135 PF13575.1 CCH59099.1 - 0.049 12.6 0.1 0.071 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Acetyltransf_4 PF13420.1 CCH59099.1 - 0.067 13.1 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG11 PF10377.4 CCH59100.1 - 8.5e-30 103.2 2.1 1.1e-29 102.8 0.1 2.4 2 0 0 2 2 2 1 Autophagy-related protein 11 Pyridox_oxase_2 PF12766.2 CCH59100.1 - 0.0046 17.2 0.1 0.015 15.6 0.1 1.9 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pox_A_type_inc PF04508.7 CCH59100.1 - 0.13 12.0 2.9 1 9.2 0.1 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Cortex-I_coil PF09304.5 CCH59100.1 - 5.7 7.0 19.3 1.8 8.6 0.6 3.8 3 1 0 3 3 3 0 Cortexillin I, coiled coil FAD_binding_1 PF00667.15 CCH59101.1 - 2.1e-28 99.2 0.0 5.7e-28 97.8 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCH59101.1 - 1e-18 67.6 0.0 2.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCH59101.1 - 1.2e-13 51.5 0.0 2.9e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CAT_RBD PF03123.10 CCH59101.1 - 0.055 13.1 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 CAT RNA binding domain tRNA-synt_2d PF01409.15 CCH59102.1 - 1.1e-39 136.1 0.1 2.1e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CCH59102.1 - 1.5e-21 76.3 0.0 4.3e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Pox_A_type_inc PF04508.7 CCH59102.1 - 0.35 10.7 3.5 0.32 10.8 0.7 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L16 PF00252.13 CCH59103.1 - 5.9e-35 119.9 0.2 9.9e-35 119.1 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 CCH59104.1 - 1.3e-17 63.5 0.2 1.8e-16 59.8 0.0 2.6 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCH59104.1 - 4.5e-09 36.1 0.7 4.5e-09 36.1 0.5 2.4 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 CCH59104.1 - 1.1e-07 32.0 0.6 3.6e-06 27.1 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH59104.1 - 0.00089 19.4 0.6 0.015 15.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CCH59104.1 - 0.015 14.3 0.0 0.039 13.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCH59104.1 - 0.016 14.8 0.0 0.056 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 CCH59104.1 - 0.017 15.1 0.1 1.3 9.0 0.0 2.5 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.1 CCH59104.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 CCH59104.1 - 0.06 12.2 0.0 0.96 8.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_10 PF12846.2 CCH59104.1 - 0.062 12.7 0.1 0.13 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain Bac_DnaA PF00308.13 CCH59104.1 - 0.092 12.3 0.5 0.95 9.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_11 PF13086.1 CCH59104.1 - 0.099 12.2 1.0 1.1 8.7 0.7 2.8 1 1 0 1 1 1 0 AAA domain Anoctamin PF04547.7 CCH59105.1 - 6.9e-48 163.4 33.8 4.5e-46 157.4 23.4 2.7 1 1 0 1 1 1 1 Calcium-activated chloride channel Pol_alpha_B_N PF08418.5 CCH59106.1 - 4.5e-60 203.3 5.4 6.8e-60 202.7 3.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 CCH59106.1 - 4.7e-47 159.9 0.9 7.5e-47 159.2 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CLASP_N PF12348.3 CCH59107.1 - 6.4e-61 205.6 16.3 4.9e-59 199.4 4.4 2.7 2 0 0 2 2 2 2 CLASP N terminal zf-RING_2 PF13639.1 CCH59109.1 - 3.4e-08 33.1 12.0 3.4e-08 33.1 8.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CCH59109.1 - 1.9e-07 30.6 9.8 1.9e-07 30.6 6.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH59109.1 - 2.6e-07 30.3 13.2 2.6e-07 30.3 9.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CCH59109.1 - 3.8e-07 29.6 14.8 2.4e-06 27.0 5.4 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH59109.1 - 6.7e-07 29.2 12.2 6.7e-07 29.2 8.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH59109.1 - 3.1e-05 23.6 4.2 8.6e-05 22.1 2.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CCH59109.1 - 0.0007 19.2 10.0 0.0007 19.2 6.9 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-ribbon_3 PF13248.1 CCH59109.1 - 0.01 15.0 5.3 0.071 12.3 1.3 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCH59109.1 - 0.18 11.3 7.6 32 4.1 2.8 3.9 2 1 0 2 2 2 0 zinc-ribbon domain zf-UDP PF14569.1 CCH59109.1 - 0.38 10.5 12.9 0.53 10.0 0.0 3.5 4 0 0 4 4 3 0 Zinc-binding RING-finger zf-Apc11 PF12861.2 CCH59109.1 - 0.65 9.8 7.6 0.098 12.5 2.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCH59109.1 - 0.73 9.9 12.3 0.18 11.9 5.1 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 CCH59109.1 - 0.74 9.6 12.6 0.21 11.4 0.3 2.9 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 CCH59109.1 - 3.7 7.4 10.2 2.9 7.7 0.1 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain EamA PF00892.15 CCH59111.1 - 4.3e-26 91.4 25.0 1.1e-13 51.3 5.3 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CCH59111.1 - 5.8e-07 29.6 7.6 5.8e-07 29.6 5.3 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 CCH59111.1 - 0.00025 20.0 10.4 0.018 13.9 2.7 2.1 2 0 0 2 2 2 2 UAA transporter family RseC_MucC PF04246.7 CCH59111.1 - 0.014 14.9 5.2 3.5 7.1 0.3 3.7 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC TPT PF03151.11 CCH59111.1 - 0.54 9.8 22.3 0.099 12.2 5.1 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF3021 PF11457.3 CCH59111.1 - 7.8 6.3 25.3 0.023 14.5 6.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Ecm33 PF12454.3 CCH59112.1 - 0.12 12.2 0.4 0.12 12.2 0.3 1.9 1 1 1 2 2 2 0 GPI-anchored cell wall organization protein PT-VENN PF04829.8 CCH59112.1 - 1.6 8.3 9.3 2.5 7.7 0.4 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif SAM_decarbox PF01536.11 CCH59113.1 - 2.3e-103 345.3 2.6 2.7e-103 345.1 1.8 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Glyco_transf_8 PF01501.15 CCH59114.1 - 1.2e-09 37.8 6.2 1.5e-09 37.6 2.5 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 8 Pet20 PF08692.5 CCH59114.1 - 0.0087 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Latarcin PF10279.4 CCH59114.1 - 0.093 12.9 0.8 0.46 10.7 0.3 2.3 2 0 0 2 2 2 0 Latarcin precursor RRM_1 PF00076.17 CCH59115.1 - 5.5e-21 73.9 3.5 3e-13 49.1 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59115.1 - 4.7e-16 58.5 0.3 2.6e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59115.1 - 9.1e-09 35.0 7.2 2e-05 24.3 1.5 3.4 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 CCH59115.1 - 0.15 11.4 1.2 0.55 9.5 0.1 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.1 CCH59115.1 - 0.15 11.8 0.1 0.55 10.0 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AMP-binding PF00501.23 CCH59116.1 - 5.5e-85 285.2 0.0 8.9e-85 284.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCH59116.1 - 0.066 14.1 0.0 0.21 12.5 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Flp_C PF05202.7 CCH59117.1 - 2.6e-36 125.0 2.7 3.5e-34 118.1 0.9 2.6 2 0 0 2 2 2 2 Recombinase Flp protein Flp_N PF03930.9 CCH59117.1 - 0.00019 21.1 1.2 0.00049 19.8 0.8 1.6 1 0 0 1 1 1 1 Recombinase Flp protein N-terminus DUF4458 PF14660.1 CCH59117.1 - 0.12 12.4 1.1 0.24 11.3 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4458) COX6B PF02297.12 CCH59118.1 - 1.9e-19 69.4 4.7 2.6e-19 69.0 3.2 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CCH59118.1 - 0.0012 18.7 1.3 0.002 18.1 0.9 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 hSH3 PF14603.1 CCH59118.1 - 0.07 13.1 0.1 0.079 12.9 0.1 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain DUF1428 PF07237.6 CCH59118.1 - 0.14 12.1 0.7 0.22 11.4 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) Bac_rhodopsin PF01036.13 CCH59119.1 - 1.1e-48 165.5 14.9 1.3e-48 165.2 10.3 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4504 PF14953.1 CCH59119.1 - 0.071 12.3 1.6 9 5.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4504) SUN PF03856.8 CCH59120.1 - 1.5e-85 286.4 20.2 1.9e-85 286.1 14.0 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) IcmL PF11393.3 CCH59121.1 - 0.42 10.5 3.4 12 5.8 0.0 2.9 2 1 1 3 3 3 0 Macrophage killing protein with similarity to conjugation protein Atrophin-1 PF03154.10 CCH59122.1 - 0.00019 19.7 2.9 0.00019 19.7 2.0 1.9 2 0 0 2 2 2 1 Atrophin-1 family Endonuc_Holl PF10107.4 CCH59122.1 - 0.027 14.1 5.2 0.11 12.1 3.3 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase NARP1 PF12569.3 CCH59122.1 - 0.2 10.3 10.6 0.34 9.6 7.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.5 CCH59122.1 - 5.9 6.6 9.1 18 5.0 6.3 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_L18ae PF01775.12 CCH59123.1 - 6.5e-58 194.0 1.4 9.3e-58 193.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF1057 PF06342.7 CCH59123.1 - 0.035 12.9 0.1 0.053 12.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) CTP_transf_1 PF01148.15 CCH59124.1 - 2.7e-20 73.1 11.3 4.7e-19 69.0 7.8 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family MFS_1 PF07690.11 CCH59124.1 - 0.0075 15.0 3.4 0.011 14.4 2.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Nop PF01798.13 CCH59125.1 - 2.5e-59 198.8 1.0 1.4e-58 196.4 0.8 2.2 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CCH59125.1 - 2.7e-27 94.3 0.3 9.7e-27 92.5 0.0 2.1 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCH59125.1 - 4e-18 65.3 1.2 4e-18 65.3 0.9 3.0 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 CCH59125.1 - 0.33 10.8 23.4 0.73 9.7 16.2 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 CCH59125.1 - 9.7 4.8 33.0 10 4.7 22.0 1.9 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SART-1 PF03343.8 CCH59126.1 - 3.2e-52 177.7 77.0 1.2e-51 175.8 53.4 1.7 1 1 0 1 1 1 1 SART-1 family TPT PF03151.11 CCH59127.1 - 7.6e-24 84.1 8.1 7.6e-24 84.1 5.6 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family PIRT PF15099.1 CCH59127.1 - 1.8 7.8 8.9 5.7 6.1 0.6 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DUF2034 PF10356.4 CCH59128.1 - 2.3e-48 163.7 0.0 2.8e-48 163.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CCH59128.1 - 0.00027 20.7 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease Ribonuclease_3 PF00636.21 CCH59129.1 - 1.1e-17 64.4 0.0 3.8e-17 62.7 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCH59129.1 - 6.9e-14 51.9 0.1 1.8e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCH59129.1 - 9e-06 26.1 0.1 7.6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif Nucleic_acid_bd PF13820.1 CCH59129.1 - 0.037 13.6 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative nucleic acid-binding region Ku PF02735.11 CCH59131.1 - 2.8e-36 124.8 0.1 6.8e-36 123.5 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCH59131.1 - 1.9e-21 76.5 8.4 1.9e-21 76.5 5.8 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CCH59131.1 - 2.5e-07 31.1 0.9 9.9e-07 29.2 0.5 2.3 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm Exo_endo_phos PF03372.18 CCH59132.1 - 1.4e-22 80.9 0.0 1.8e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.15 CCH59133.1 - 2e-12 46.4 0.1 2.6e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNB PF00773.14 CCH59134.1 - 2.3e-67 227.6 3.6 2.3e-67 227.6 2.5 2.3 2 0 0 2 2 2 1 RNB domain RNA_pol_Rpb5_C PF01191.14 CCH59134.1 - 0.31 10.6 2.1 8.8 6.0 0.3 2.8 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF3994 PF13159.1 CCH59134.1 - 0.77 10.0 8.3 0.15 12.3 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Gtr1_RagA PF04670.7 CCH59135.1 - 1.5e-93 312.2 4.5 2e-93 311.8 3.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCH59135.1 - 1.2e-08 34.4 0.5 3.8e-08 32.8 0.1 1.9 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CCH59135.1 - 5e-07 30.2 0.3 1.5e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCH59135.1 - 9.3e-07 28.2 1.7 1.1e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCH59135.1 - 3e-06 27.1 0.1 1.2e-05 25.2 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCH59135.1 - 0.011 16.0 0.3 0.024 14.9 0.0 1.9 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 CCH59135.1 - 0.012 15.1 0.2 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 CCH59135.1 - 0.18 10.8 4.0 0.27 10.2 0.1 2.6 2 2 0 3 3 3 0 AIG1 family DUF262 PF03235.9 CCH59135.1 - 1.3 8.9 7.8 0.78 9.6 4.0 1.5 1 1 0 2 2 2 0 Protein of unknown function DUF262 Sugar_tr PF00083.19 CCH59136.1 - 3.3e-39 134.7 14.5 2.5e-27 95.5 2.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCH59136.1 - 5.8e-19 68.0 13.4 2.5e-17 62.6 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin PF00091.20 CCH59137.1 - 1.7e-71 240.4 0.0 2.4e-71 239.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCH59137.1 - 1.3e-48 164.2 0.2 2.1e-48 163.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CCH59137.1 - 0.0046 16.4 0.0 0.052 13.0 0.0 2.3 2 0 0 2 2 2 1 Tubulin domain ALO PF04030.9 CCH59138.1 - 2.7e-101 338.5 0.9 4.3e-101 337.8 0.7 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CCH59138.1 - 8.6e-28 96.5 0.0 1.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SIS_2 PF13580.1 CCH59138.1 - 0.0043 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 SIS domain FAD_binding_6 PF00970.19 CCH59139.1 - 7.8e-26 90.0 0.0 1.2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCH59139.1 - 2e-24 86.2 0.0 3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCH59139.1 - 0.00029 20.7 0.0 0.0083 16.0 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CCH59139.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain F-box-like PF12937.2 CCH59140.1 - 2.4e-11 43.1 0.1 4.6e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCH59140.1 - 4.6e-08 32.5 1.0 4.6e-08 32.5 0.7 2.3 2 0 0 2 2 2 1 F-box domain UIM PF02809.15 CCH59140.1 - 0.079 12.5 32.1 0.037 13.5 2.9 5.1 5 0 0 5 5 5 0 Ubiquitin interaction motif GTP_cyclohydro2 PF00925.15 CCH59141.1 - 3.1e-54 182.7 0.0 4.3e-50 169.2 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II gag-asp_proteas PF13975.1 CCH59142.1 - 0.0038 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PhzC-PhzF PF02567.11 CCH59143.1 - 5.9e-60 202.8 0.0 6.8e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Cys_Met_Meta_PP PF01053.15 CCH59144.1 - 5.3e-61 206.0 0.0 1.2e-60 204.8 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCH59144.1 - 0.00089 18.1 0.0 0.0026 16.5 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class-V PQ-loop PF04193.9 CCH59145.1 - 7.8e-25 86.2 9.2 4.7e-20 70.9 1.4 2.9 2 1 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.1 CCH59145.1 - 0.8 8.9 22.5 0.13 11.5 8.0 2.3 1 1 0 2 2 2 0 ABC-2 family transporter protein DUF2428 PF10350.4 CCH59146.1 - 7.1e-64 215.2 0.1 2.6e-63 213.4 0.0 2.1 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CCH59146.1 - 4.6e-09 35.6 1.0 0.22 11.7 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 CCH59146.1 - 1e-07 32.1 0.9 0.00036 20.7 0.2 5.2 4 2 2 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 CCH59146.1 - 0.012 16.0 1.5 7.9 7.1 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat Glyco_transf_20 PF00982.16 CCH59147.1 - 1.2e-163 545.0 3.5 1.4e-163 544.7 0.4 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCH59147.1 - 6e-37 126.7 0.2 1e-35 122.8 0.0 2.8 3 0 0 3 3 3 1 Trehalose-phosphatase TatD_DNase PF01026.16 CCH59148.1 - 1.8e-35 122.3 0.0 2.2e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase CUE PF02845.11 CCH59149.1 - 3.7e-08 32.7 0.0 7.8e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 CUE domain RAMP4 PF06624.7 CCH59149.1 - 0.12 11.9 2.5 2.6 7.6 0.1 2.7 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 TRAP-gamma PF07074.7 CCH59149.1 - 0.16 11.4 3.6 0.27 10.7 2.5 1.5 1 1 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) ABC2_membrane_3 PF12698.2 CCH59149.1 - 0.41 9.6 4.4 0.76 8.7 3.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein MNSV_P7B PF06692.6 CCH59149.1 - 0.82 9.5 3.6 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF2410 PF10307.4 CCH59150.1 - 3.6e-45 153.7 1.7 5.1e-45 153.2 1.2 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF221 PF02714.10 CCH59151.1 - 1.3e-109 365.9 26.6 1.3e-109 365.9 18.4 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCH59151.1 - 7.7e-39 132.7 1.0 7.7e-39 132.7 0.7 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CCH59151.1 - 3.5e-29 100.5 0.0 8.8e-29 99.2 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CCH59151.1 - 9.8e-16 58.0 0.9 1.9e-15 57.1 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Nup188 PF10487.4 CCH59152.1 - 1.3e-187 625.6 52.4 1.3e-187 625.6 36.3 1.8 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 RRM_1 PF00076.17 CCH59153.1 - 3.9e-29 100.0 2.7 1.3e-11 43.8 0.1 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59153.1 - 2.6e-26 91.3 1.0 4.7e-09 36.0 0.0 3.8 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59153.1 - 1.4e-12 47.2 3.7 4.1e-07 29.7 0.1 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCH59153.1 - 6.6e-07 28.9 0.1 0.0029 17.3 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 CCH59153.1 - 0.00075 18.8 0.8 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Lsm interaction motif G-patch PF01585.18 CCH59154.1 - 0.0003 20.5 1.4 0.0014 18.3 0.9 2.2 1 1 0 1 1 1 1 G-patch domain DUF1510 PF07423.6 CCH59154.1 - 0.18 11.1 26.3 0.27 10.5 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CCH59154.1 - 0.35 10.7 18.6 0.44 10.4 12.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.17 CCH59154.1 - 1.8 7.4 7.8 2.1 7.2 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF908 PF06012.7 CCH59154.1 - 2.1 7.5 10.5 2.2 7.4 7.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) RR_TM4-6 PF06459.7 CCH59154.1 - 2.4 7.9 19.5 2.9 7.7 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Trypan_glycop PF00913.14 CCH59154.1 - 3.5 6.4 16.4 4.3 6.1 11.4 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Hex_IIIa PF02455.11 CCH59154.1 - 7.4 5.1 9.8 8.6 4.9 6.8 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PXA PF02194.10 CCH59155.1 - 5.9e-33 114.0 4.8 5.9e-33 114.0 3.3 2.3 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 CCH59155.1 - 4.4e-22 78.3 0.6 4.4e-22 78.3 0.4 2.9 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CCH59155.1 - 2.9e-15 56.0 1.7 2.9e-15 56.0 1.2 2.4 3 0 0 3 3 3 1 PX domain RRN9 PF10680.4 CCH59156.1 - 1.2e-13 50.5 0.2 2.6e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor IBN_N PF03810.14 CCH59156.1 - 0.017 15.0 0.6 0.039 13.8 0.4 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain SRP19 PF01922.12 CCH59157.1 - 2.2e-26 92.2 0.0 3.9e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein DUF3600 PF12207.3 CCH59157.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) Pribosyltran PF00156.22 CCH59158.1 - 2.7e-19 69.1 0.1 4.2e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C3HC PF07967.8 CCH59159.1 - 3.4e-07 30.1 1.4 3.4e-07 30.1 0.9 3.2 3 2 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 CCH59159.1 - 0.019 14.8 3.6 0.28 11.0 0.1 2.7 2 1 0 2 2 2 0 Rsm1-like DUF1892 PF08987.5 CCH59160.1 - 4.3e-38 129.8 10.4 5.6e-37 126.2 7.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1892) Zds_C PF08632.5 CCH59161.1 - 1.4e-31 107.6 2.0 2.9e-31 106.6 1.4 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Bul1_N PF04425.7 CCH59162.1 - 3.1e-154 513.7 11.0 3.1e-154 513.7 7.6 3.0 2 1 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCH59162.1 - 4.9e-84 281.7 27.5 1.5e-58 198.1 12.3 4.0 3 2 2 5 5 5 2 Bul1 C terminus CTK3_C PF12350.3 CCH59163.1 - 1.6e-13 50.4 5.0 2.3e-12 46.7 3.4 2.7 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 CCH59163.1 - 8.7e-06 25.4 6.6 4.5e-05 23.1 4.6 2.1 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 Sp38 PF07354.7 CCH59163.1 - 0.084 11.5 0.5 0.15 10.6 0.0 1.6 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) DUF948 PF06103.6 CCH59163.1 - 0.15 11.9 3.8 0.22 11.4 0.2 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ubiquitin PF00240.18 CCH59165.1 - 1.7e-14 52.9 0.6 3.6e-14 51.9 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCH59165.1 - 3.8e-08 32.8 0.4 7.7e-08 31.9 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CCH59165.1 - 9.8e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCH59165.1 - 0.062 13.5 0.1 0.25 11.6 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain PGM_PMM_I PF02878.11 CCH59166.1 - 4.6e-37 126.5 0.0 8e-37 125.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCH59166.1 - 3.8e-20 72.1 0.0 1.2e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CCH59166.1 - 2e-12 47.1 0.0 4e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CCH59166.1 - 2.2e-07 30.7 0.0 6.9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain S-methyl_trans PF02574.11 CCH59167.1 - 6.2e-75 252.3 0.0 7.1e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Anp1 PF03452.9 CCH59168.1 - 1.7e-124 414.3 0.0 2.4e-124 413.8 0.0 1.2 1 0 0 1 1 1 1 Anp1 BcsB PF03170.8 CCH59168.1 - 0.22 9.5 0.0 0.3 9.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Nab6_mRNP_bdg PF10567.4 CCH59169.1 - 2.6e-61 207.2 34.1 1.6e-52 178.4 7.3 5.6 4 3 0 4 4 4 2 RNA-recognition motif RRM PF10378.4 CCH59169.1 - 1.5e-15 56.5 11.6 1.5e-15 56.5 8.1 3.1 2 1 0 2 2 2 1 Putative RRM domain RRM_6 PF14259.1 CCH59169.1 - 3.7e-12 46.0 0.8 8.4e-05 22.4 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59169.1 - 1.9e-09 37.2 3.3 0.00048 19.9 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH59169.1 - 3.4e-08 32.9 0.9 0.071 12.7 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIG-L PF02585.12 CCH59171.1 - 1.7e-12 47.9 0.0 2.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 CCH59172.1 - 4.3e-11 42.2 2.5 4.3e-11 42.2 1.7 2.9 2 1 0 2 2 2 1 Mitochondrial ATPase expression PPR PF01535.15 CCH59172.1 - 0.054 13.4 0.0 15 5.8 0.0 3.5 3 0 0 3 3 3 0 PPR repeat Glyco_hydro_76 PF03663.9 CCH59173.1 - 5e-147 490.1 19.4 6.1e-147 489.8 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ChAPs PF09295.5 CCH59174.1 - 7e-172 571.6 2.2 9.8e-172 571.1 1.5 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCH59174.1 - 1.1e-05 24.9 1.8 0.44 10.2 0.1 3.8 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 CCH59174.1 - 2e-05 24.1 1.7 0.075 12.9 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCH59174.1 - 0.00039 19.9 0.0 0.13 12.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCH59174.1 - 0.00083 19.6 0.7 0.26 11.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCH59174.1 - 0.001 19.4 0.1 29 5.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCH59174.1 - 0.0026 17.3 0.2 3.4 7.4 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCH59174.1 - 0.0036 17.7 0.0 18 6.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59174.1 - 0.0086 16.7 0.0 2.7 8.7 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCH59174.1 - 0.01 15.9 2.6 1.1 9.4 0.1 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HSBP1 PF06825.7 CCH59174.1 - 0.049 13.2 0.9 0.21 11.2 0.6 2.0 1 0 0 1 1 1 0 Heat shock factor binding protein 1 TPR_7 PF13176.1 CCH59174.1 - 0.13 12.1 0.2 13 5.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID-31kDa PF02291.10 CCH59175.1 - 5.2e-53 178.2 1.4 1.5e-51 173.5 0.9 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Secretin_N_2 PF07655.8 CCH59175.1 - 0.019 15.3 6.0 2.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Acyltransferase PF01553.16 CCH59176.1 - 0.00032 20.1 0.3 0.0026 17.1 0.1 2.5 1 1 1 2 2 2 1 Acyltransferase GSH_synthase PF03199.10 CCH59176.1 - 0.25 11.4 1.9 0.34 11.0 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic glutathione synthase SWIB PF02201.13 CCH59177.1 - 1.3e-24 85.6 0.2 2.5e-24 84.7 0.2 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CCH59177.1 - 7.4e-09 35.2 0.0 6.2e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain MRP-S31 PF15433.1 CCH59177.1 - 0.051 12.9 3.8 0.062 12.7 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2500 PF10694.4 CCH59177.1 - 0.2 11.6 1.4 0.37 10.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) VPS11_C PF12451.3 CCH59178.1 - 4.8e-09 35.9 0.0 1.5e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 CCH59178.1 - 0.00041 20.0 7.2 0.00041 20.0 5.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCH59178.1 - 0.00084 19.1 6.0 0.0021 17.8 4.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH59178.1 - 0.0015 18.5 6.6 0.0041 17.1 4.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCH59178.1 - 0.006 16.6 2.5 0.019 15.0 1.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCH59178.1 - 0.0069 16.2 1.0 0.016 15.0 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CCH59178.1 - 0.089 12.6 9.4 0.021 14.6 3.9 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.24 CCH59178.1 - 0.096 12.3 10.8 0.018 14.7 3.2 2.4 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.1 CCH59178.1 - 0.21 11.7 6.9 3.6 7.7 0.1 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4 PF00097.20 CCH59178.1 - 2.6 7.7 12.0 0.27 10.9 5.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mpv17_PMP22 PF04117.7 CCH59179.1 - 6.9e-17 60.8 4.5 6.9e-17 60.8 3.1 2.6 1 1 2 3 3 3 1 Mpv17 / PMP22 family Phage_holin_3 PF05106.7 CCH59179.1 - 0.065 13.2 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) RrnaAD PF00398.15 CCH59180.1 - 4.7e-31 107.7 0.0 5.7e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase AMMECR1 PF01871.12 CCH59181.1 - 4.3e-37 126.8 0.0 5.7e-37 126.4 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.20 CCH59182.1 - 6e-12 45.7 0.0 8.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH59182.1 - 0.00057 19.6 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCH59182.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FSH1 PF03959.8 CCH59183.1 - 1.2e-55 188.2 0.0 1.6e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCH59183.1 - 1.3e-08 34.6 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCH59183.1 - 3.3e-05 23.4 0.0 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase MFS_1 PF07690.11 CCH59184.1 - 0.024 13.3 42.4 0.036 12.7 26.2 3.0 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF788 PF05620.6 CCH59184.1 - 1.7 8.4 11.1 0.056 13.2 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) GHMP_kinases_N PF00288.21 CCH59186.1 - 1.6e-13 50.4 2.2 3.8e-13 49.2 0.7 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCH59186.1 - 0.0013 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DIX PF00778.12 CCH59186.1 - 0.034 13.8 0.1 0.33 10.6 0.0 2.5 2 1 0 2 2 2 0 DIX domain TRAPPC10 PF12584.3 CCH59188.1 - 2e-13 50.0 0.0 4.2e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 CCH59188.1 - 0.011 15.5 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.3 CCH59188.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_11 PF13414.1 CCH59188.1 - 0.036 13.7 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.12 CCH59188.1 - 0.046 13.6 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_helicase PF00910.17 CCH59188.1 - 0.12 12.6 4.4 1 9.5 0.2 3.3 2 1 1 3 3 3 0 RNA helicase HEM4 PF02602.10 CCH59189.1 - 2.9e-33 115.0 0.0 3.3e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF1506 PF07405.6 CCH59189.1 - 0.055 13.4 1.4 3.5 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) DnaJ PF00226.26 CCH59190.1 - 2.4e-22 78.4 7.5 4.1e-22 77.6 5.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCH59190.1 - 2.2e-15 56.4 15.3 3.3e-15 55.8 10.6 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CCH59190.1 - 6.4e-13 48.4 0.1 8.3e-11 41.6 0.0 2.9 3 0 0 3 3 3 1 DnaJ C terminal domain DZR PF12773.2 CCH59190.1 - 0.47 10.3 9.6 1.7 8.5 6.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon Myb_DNA-binding PF00249.26 CCH59192.1 - 1.1e-17 63.7 3.0 2.5e-12 46.6 0.2 3.1 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH59192.1 - 2.7e-15 56.2 1.0 4.3e-11 42.7 0.6 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 CCH59192.1 - 0.015 15.0 0.1 1.7 8.4 0.0 2.9 2 0 0 2 2 2 0 SLIDE MADF_DNA_bdg PF10545.4 CCH59192.1 - 2.6 8.3 8.8 15 5.8 0.1 4.0 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like gag_pre-integrs PF13976.1 CCH59193.1 - 0.026 14.1 0.2 0.22 11.1 0.0 2.8 2 0 0 2 2 2 0 GAG-pre-integrase domain FANCI_S1-cap PF14674.1 CCH59193.1 - 0.6 10.1 4.8 0.63 10.1 0.0 3.1 3 0 0 3 3 3 0 FANCI solenoid 1 cap Tubulin_3 PF14881.1 CCH59194.1 - 1.8e-25 89.4 0.5 5e-25 88.0 0.1 1.9 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCH59194.1 - 5.5e-20 71.5 0.5 5.5e-20 71.5 0.3 2.3 2 1 1 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CCH59194.1 - 0.011 15.6 0.0 0.079 12.7 0.0 2.2 2 1 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain Thr_synth_N PF14821.1 CCH59194.1 - 0.067 13.2 0.1 1 9.4 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus MFS_1 PF07690.11 CCH59195.1 - 4e-09 35.6 4.1 4.9e-09 35.3 2.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily N2227 PF07942.7 CCH59196.1 - 3.5e-63 213.1 0.4 7.3e-63 212.0 0.3 1.5 1 0 0 1 1 1 1 N2227-like protein OMP_b-brl PF13505.1 CCH59196.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain WD40 PF00400.27 CCH59197.1 - 2.5e-34 115.8 10.8 7.4e-08 31.9 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 CCH59197.1 - 3.3e-24 84.6 1.3 6.9e-24 83.6 0.4 2.0 2 0 0 2 2 2 1 NLE (NUC135) domain Nup160 PF11715.3 CCH59197.1 - 6.8e-06 24.4 6.0 0.016 13.4 0.3 3.4 2 2 1 3 3 3 3 Nucleoporin Nup120/160 V_ATPase_I PF01496.14 CCH59198.1 - 1e-285 949.4 13.4 1.2e-285 949.2 9.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 CCH59198.1 - 0.07 12.9 0.2 0.07 12.9 0.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_9 PF05434.6 CCH59198.1 - 0.074 12.7 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 TMEM9 Pkinase PF00069.20 CCH59199.1 - 2.2e-57 194.1 0.7 1.5e-53 181.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59199.1 - 1.9e-20 73.0 0.0 6e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59199.1 - 0.00013 21.0 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TBCA PF02970.11 CCH59201.1 - 6.5e-29 99.8 12.3 7.7e-29 99.6 8.5 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A rve_2 PF13333.1 CCH59201.1 - 0.01 15.9 4.4 0.17 11.9 0.1 2.3 2 0 0 2 2 2 1 Integrase core domain CENP-Q PF13094.1 CCH59201.1 - 0.028 14.4 6.5 0.037 14.0 4.5 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cytochrom_C_2 PF01322.15 CCH59201.1 - 0.054 14.0 0.1 0.068 13.7 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C' DUF342 PF03961.8 CCH59201.1 - 0.09 11.1 9.3 0.098 11.0 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hanta_nucleocap PF00846.13 CCH59201.1 - 0.24 10.0 2.1 0.26 9.9 1.4 1.1 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein IncA PF04156.9 CCH59201.1 - 0.24 10.9 9.9 0.32 10.5 6.8 1.1 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 CCH59201.1 - 0.28 9.0 6.5 0.33 8.8 4.5 1.0 1 0 0 1 1 1 0 Hsp70 protein Atg14 PF10186.4 CCH59201.1 - 0.4 9.5 4.6 0.49 9.2 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 CCH59201.1 - 0.58 10.1 9.1 0.73 9.8 6.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.10 CCH59201.1 - 0.7 9.0 5.3 0.82 8.8 3.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.3 CCH59201.1 - 0.73 9.8 7.4 2.7 8.0 2.6 2.0 1 1 1 2 2 2 0 YlqD protein Scaffolding_pro PF11418.3 CCH59201.1 - 0.91 9.8 7.4 9.6 6.5 0.5 2.1 1 1 1 2 2 2 0 Phi29 scaffolding protein Phage_GP20 PF06810.6 CCH59201.1 - 1 8.7 14.1 1.1 8.7 5.9 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 NYD-SP28 PF14772.1 CCH59201.1 - 1.2 9.2 10.1 0.81 9.8 1.4 2.2 2 0 0 2 2 2 0 Sperm tail NPV_P10 PF05531.7 CCH59201.1 - 1.2 9.4 3.8 8.6 6.6 2.6 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.4 CCH59201.1 - 1.3 9.2 4.3 4.5 7.5 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FlxA PF14282.1 CCH59201.1 - 4.1 7.3 8.7 22 5.0 0.2 2.4 1 1 1 2 2 2 0 FlxA-like protein DUF919 PF06034.6 CCH59201.1 - 9.1 5.9 9.4 2.2 7.9 1.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) MitMem_reg PF13012.1 CCH59203.1 - 8.8e-39 132.1 3.4 8.8e-39 132.1 2.4 2.8 3 1 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCH59203.1 - 7.8e-29 99.7 0.6 1.5e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease His_Phos_1 PF00300.17 CCH59203.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) APG12 PF04110.8 CCH59203.1 - 0.29 11.3 3.0 0.51 10.5 0.2 2.6 3 0 0 3 3 3 0 Ubiquitin-like autophagy protein Apg12 HIT PF01230.18 CCH59204.1 - 1.2e-16 61.0 0.1 3e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCH59204.1 - 2e-14 53.8 2.0 1.2e-13 51.3 1.4 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding KOW PF00467.24 CCH59205.1 - 0.0068 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 KOW motif EF-hand_7 PF13499.1 CCH59206.1 - 1.2e-24 86.2 18.0 3.5e-14 52.6 2.0 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CCH59206.1 - 2.9e-22 76.1 15.1 2.5e-07 29.4 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCH59206.1 - 4.2e-19 66.6 13.9 3.5e-06 26.4 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CCH59206.1 - 1.1e-15 56.1 8.1 5.9e-05 22.2 0.2 4.0 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CCH59206.1 - 2.3e-15 55.9 14.6 9.6e-11 41.1 0.7 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CCH59206.1 - 9.8e-05 22.0 3.4 0.032 13.9 0.2 2.3 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCH59206.1 - 0.00032 20.5 0.2 0.013 15.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.8 CCH59206.1 - 0.016 14.7 0.1 0.12 11.8 0.0 2.3 2 1 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.4 CCH59206.1 - 0.035 14.1 3.4 1.9 8.5 0.3 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4373 PF14297.1 CCH59206.1 - 0.059 13.6 0.6 4.8 7.5 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4373) MgtE_N PF03448.12 CCH59206.1 - 0.11 12.8 2.9 0.17 12.2 0.2 2.3 3 0 0 3 3 3 0 MgtE intracellular N domain VCBS PF13517.1 CCH59206.1 - 0.11 12.8 2.6 1.6 9.1 0.1 2.6 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella VASP_tetra PF08776.6 CCH59206.1 - 0.12 11.7 3.5 0.23 10.8 1.1 2.5 3 0 0 3 3 3 0 VASP tetramerisation domain TBPIP PF07106.8 CCH59206.1 - 0.23 10.9 1.6 1.3 8.5 0.1 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) EF-hand_like PF09279.6 CCH59206.1 - 0.43 10.6 4.8 0.96 9.5 0.2 2.7 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like RloB PF13707.1 CCH59206.1 - 0.66 9.5 3.1 4.2 6.9 2.0 2.1 1 1 0 1 1 1 0 RloB-like protein Crinivirus_P26 PF07416.6 CCH59206.1 - 0.66 9.4 3.7 0.2 11.1 0.5 1.6 2 1 0 2 2 2 0 Crinivirus P26 protein CAP_GLY PF01302.20 CCH59207.1 - 9.6e-22 76.4 0.6 1.6e-21 75.7 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain BHD_1 PF10403.4 CCH59207.1 - 0.21 11.1 3.1 5.3 6.6 0.0 3.0 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 1 Med9 PF07544.8 CCH59207.1 - 0.89 9.3 22.0 0.22 11.2 0.5 4.1 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TFR_dimer PF04253.10 CCH59208.1 - 5.8e-33 113.1 0.0 2.1e-32 111.3 0.0 2.0 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Nicastrin PF05450.10 CCH59208.1 - 0.0014 17.9 0.0 0.003 16.8 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 CCH59208.1 - 0.0057 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 Cyt-b5 PF00173.23 CCH59209.1 - 4.9e-10 39.0 0.0 8e-10 38.3 0.0 1.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FNIP PF05725.7 CCH59210.1 - 0.33 10.9 7.6 2.8 7.9 0.1 3.3 3 0 0 3 3 3 0 FNIP Repeat TAP_C PF03943.8 CCH59211.1 - 1e-13 50.4 0.0 2.8e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.1 CCH59211.1 - 7.2e-07 28.9 0.4 1.6e-06 27.8 0.3 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCH59211.1 - 8.7e-05 22.0 1.4 8.7e-05 22.0 1.0 3.8 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 CCH59211.1 - 0.00037 20.8 0.2 0.024 15.0 0.3 3.0 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain DUF732 PF05305.9 CCH59211.1 - 0.055 13.5 0.2 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF732) PDH PF02153.12 CCH59211.1 - 0.11 11.4 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase LRR_6 PF13516.1 CCH59211.1 - 1.2 9.4 8.3 0.6 10.3 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 CCH59211.1 - 1.5 9.1 5.2 16 6.0 0.1 4.7 3 1 1 4 4 4 0 Leucine Rich Repeat Sec63 PF02889.11 CCH59212.1 - 1.3e-18 67.3 0.2 1.3e-15 57.4 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 CCH59212.1 - 1.9e-18 65.9 3.3 3.7e-18 65.0 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain DUF4014 PF13198.1 CCH59212.1 - 0.029 14.7 0.0 0.087 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DUF221 PF02714.10 CCH59212.1 - 0.045 12.6 0.2 10 4.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF221 LEM PF03020.10 CCH59212.1 - 0.07 12.5 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 LEM domain DUF2881 PF11087.3 CCH59212.1 - 0.086 12.3 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2881) Acetyltransf_1 PF00583.19 CCH59213.1 - 1.3e-15 57.2 0.2 1.7e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCH59213.1 - 4.8e-10 39.4 0.2 7.5e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCH59213.1 - 9e-09 35.4 0.5 1.1e-08 35.1 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCH59213.1 - 2.8e-07 30.1 0.0 4.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCH59213.1 - 1.2e-06 28.5 0.0 1.7e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCH59213.1 - 2.4e-06 27.5 0.0 3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCH59213.1 - 0.0071 16.5 0.0 0.0079 16.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCH59213.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCH59213.1 - 0.082 12.7 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 CCH59213.1 - 0.11 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF2962 PF11176.3 CCH59215.1 - 5.2e-52 175.5 7.4 6.1e-52 175.2 5.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MRC1 PF09444.5 CCH59215.1 - 0.064 13.5 6.3 0.1 12.9 4.4 1.4 1 0 0 1 1 1 0 MRC1-like domain adh_short PF00106.20 CCH59217.1 - 2.6e-12 46.9 0.0 4.3e-10 39.7 0.0 2.9 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCH59217.1 - 2.4e-07 30.7 0.0 7e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCH59217.1 - 0.0002 20.8 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCH59217.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CCH59217.1 - 0.06 12.4 0.6 0.68 9.0 0.4 2.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CCH59217.1 - 0.089 12.7 0.0 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 NADH(P)-binding tRNA-synt_1 PF00133.17 CCH59218.1 - 9e-44 149.4 0.0 8.4e-35 119.8 0.0 2.8 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCH59218.1 - 1.2e-19 70.2 0.1 9e-11 41.0 0.0 4.2 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCH59218.1 - 5.7e-12 45.6 0.0 1.6e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCH59218.1 - 7.3e-07 28.5 0.0 1.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Pet20 PF08692.5 CCH59219.1 - 8.9e-22 77.5 3.7 2e-10 40.7 0.1 3.0 2 1 0 3 3 3 2 Mitochondrial protein Pet20 Asp PF00026.18 CCH59222.1 - 1.3e-107 359.7 0.0 1.6e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH59222.1 - 3.7e-10 39.9 0.0 7.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCH59222.1 - 6.6e-05 22.5 0.0 0.00045 19.7 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CCH59222.1 - 0.00042 20.7 0.0 0.055 13.9 0.0 2.8 3 0 0 3 3 3 1 Aspartyl protease Pkinase PF00069.20 CCH59223.1 - 1.8e-77 260.0 0.0 3.9e-77 258.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59223.1 - 2.2e-39 135.1 0.0 4.2e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCH59223.1 - 4.9e-26 90.6 1.0 1.1e-14 54.2 0.0 3.4 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.1 CCH59223.1 - 1.5e-11 43.7 0.0 3.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH59223.1 - 1.1e-05 24.5 0.0 2.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH59223.1 - 5.6e-05 22.9 0.0 0.017 14.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Mur_ligase_M PF08245.7 CCH59224.1 - 5.7e-05 23.2 0.6 0.0017 18.4 0.4 2.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CCH59224.1 - 0.0073 16.3 0.0 0.027 14.5 0.0 2.0 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Pkinase PF00069.20 CCH59225.1 - 1.6e-64 217.5 0.0 2.9e-64 216.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59225.1 - 6.6e-36 123.7 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59225.1 - 1e-05 24.6 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SGT1 PF07093.6 CCH59226.1 - 6.8e-37 127.1 0.8 9.5e-37 126.6 0.6 1.2 1 0 0 1 1 1 1 SGT1 protein Methyltransf_23 PF13489.1 CCH59227.1 - 2.8e-15 56.4 0.0 5.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH59227.1 - 6e-14 51.9 0.1 1.6e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH59227.1 - 2.3e-11 44.0 0.3 7.2e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH59227.1 - 1.4e-09 38.5 0.0 2.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH59227.1 - 3.5e-07 30.6 0.0 8.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH59227.1 - 7.5e-07 29.4 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCH59227.1 - 5.2e-06 25.6 0.1 2.1e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CCH59227.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 CCH59227.1 - 0.014 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 CCH59227.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 CCH59227.1 - 0.04 13.6 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1694 PF07997.6 CCH59227.1 - 0.049 13.5 0.0 0.27 11.1 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) ACPS PF01648.15 CCH59228.1 - 3.2e-12 46.2 0.0 6.1e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF1749 PF08538.5 CCH59229.1 - 8.8e-102 340.0 0.0 1e-101 339.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 CCH59229.1 - 6.3e-10 38.9 0.0 3.7e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH59229.1 - 1.2e-07 31.8 0.0 1.5e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCH59229.1 - 1.6e-06 27.5 0.0 0.00024 20.4 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CCH59229.1 - 2.4e-05 24.0 0.0 0.00046 19.8 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 CCH59229.1 - 0.021 14.2 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Ndr PF03096.9 CCH59229.1 - 0.044 12.2 0.0 0.061 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family COesterase PF00135.23 CCH59229.1 - 0.049 12.3 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF2974 PF11187.3 CCH59229.1 - 0.056 12.8 0.0 0.083 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.2 CCH59229.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF900 PF05990.7 CCH59229.1 - 0.15 11.3 0.2 0.48 9.7 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) Oxysterol_BP PF01237.13 CCH59231.1 - 2.9e-83 279.2 2.9 4e-83 278.8 2.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DHFR_1 PF00186.14 CCH59232.1 - 2.2e-24 85.8 0.0 4.2e-24 84.9 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase RibD_C PF01872.12 CCH59232.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain chaperone_DMP PF10448.4 CCH59233.1 - 2e-10 40.7 0.4 2.2e-10 40.6 0.3 1.1 1 0 0 1 1 1 1 20S proteasome chaperone Ribosomal_L35Ae PF01247.13 CCH59234.1 - 6.2e-42 141.2 0.8 6.9e-42 141.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCH59234.1 - 0.0019 18.0 0.0 0.83 9.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.20 CCH59235.1 - 7.1e-66 222.0 0.0 1.5e-65 220.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59235.1 - 5e-37 127.3 0.0 8.2e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59235.1 - 1.7e-06 27.2 0.0 2.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH59235.1 - 0.083 11.9 0.0 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH59235.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GrpE PF01025.14 CCH59236.1 - 2.3e-49 167.1 10.6 4.2e-49 166.2 7.3 1.4 1 1 0 1 1 1 1 GrpE Uds1 PF15456.1 CCH59236.1 - 0.0026 17.7 3.6 0.0044 17.0 2.5 1.4 1 0 0 1 1 1 1 Up-regulated During Septation Atg14 PF10186.4 CCH59236.1 - 0.057 12.3 6.3 0.078 11.9 4.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nup54 PF13874.1 CCH59236.1 - 0.12 12.0 5.1 0.2 11.3 3.5 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 V_ATPase_I PF01496.14 CCH59236.1 - 0.25 9.1 5.5 0.27 9.0 3.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mem_trans PF03547.13 CCH59236.1 - 0.69 8.1 2.6 0.86 7.8 1.8 1.1 1 0 0 1 1 1 0 Membrane transport protein UCH PF00443.24 CCH59236.1 - 1.1 8.2 6.3 1.3 8.0 4.3 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase bZIP_1 PF00170.16 CCH59236.1 - 1.2 9.0 12.5 0.11 12.5 2.8 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF4337 PF14235.1 CCH59236.1 - 1.6 8.5 8.4 0.78 9.5 4.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) Lectin_N PF03954.9 CCH59236.1 - 1.7 8.0 5.9 16 4.9 3.2 2.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain IncA PF04156.9 CCH59236.1 - 3.3 7.2 16.3 11 5.5 11.3 1.8 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 CCH59237.1 - 9.1e-68 228.2 0.0 2.7e-67 226.6 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59237.1 - 1.1e-36 126.2 0.0 2.3e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59237.1 - 3.1e-08 32.9 0.0 5.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH59237.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 CCH59238.1 - 2.3e-07 30.4 6.7 0.0025 17.6 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Mito_carr PF00153.22 CCH59240.1 - 3.6e-64 212.5 0.6 4.6e-23 80.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl_transf_1 PF00698.16 CCH59241.1 - 4.4e-07 29.5 0.0 1e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Acyl transferase domain DPPIV_N PF00930.16 CCH59242.1 - 4.4e-89 298.5 7.3 6.3e-89 298.0 5.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCH59242.1 - 2.9e-50 170.4 0.2 5.2e-50 169.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCH59242.1 - 3.2e-07 30.1 0.0 2.4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH59242.1 - 0.0002 21.2 0.0 0.0074 16.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribonucleas_3_3 PF14622.1 CCH59243.1 - 0.34 10.8 2.0 0.38 10.6 0.2 1.9 2 0 0 2 2 2 0 Ribonuclease-III-like YEATS PF03366.11 CCH59244.1 - 1.6e-25 88.6 0.0 2.6e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 YEATS family WD40 PF00400.27 CCH59245.1 - 1.3e-33 113.6 26.4 2.5e-06 27.1 0.4 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup88 PF10168.4 CCH59245.1 - 0.013 13.4 0.8 0.02 12.7 0.6 1.2 1 0 0 1 1 1 0 Nuclear pore component SecIII_SopE_N PF05364.9 CCH59245.1 - 0.1 12.4 1.0 0.3 10.9 0.3 2.0 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus TRF PF08558.5 CCH59246.1 - 5.2e-50 170.0 0.1 1.1e-49 168.9 0.1 1.5 1 1 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 CCH59246.1 - 3e-05 23.9 0.1 5.8e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH59246.1 - 0.0087 16.1 0.1 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Linker_histone PF00538.14 CCH59247.1 - 6.7e-43 144.6 8.2 5.8e-23 80.7 0.4 2.7 3 0 0 3 3 3 2 linker histone H1 and H5 family DUF1911 PF08929.5 CCH59247.1 - 0.00083 20.0 1.4 0.68 10.6 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1911) Kp4 PF09044.5 CCH59247.1 - 0.021 14.6 0.1 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Kp4 OST-HTH PF12872.2 CCH59247.1 - 0.023 14.5 0.1 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 OST-HTH/LOTUS domain BrkDBD PF09607.5 CCH59247.1 - 0.029 13.9 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain FliE PF02049.13 CCH59247.1 - 0.12 12.4 10.0 3.5 7.7 3.0 3.5 2 1 1 3 3 3 0 Flagellar hook-basal body complex protein FliE AHH PF14412.1 CCH59247.1 - 0.43 10.6 4.0 6.7 6.7 0.2 2.4 2 1 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Dynamin_N PF00350.18 CCH59248.1 - 2.2e-41 141.4 0.1 2.2e-41 141.4 0.1 3.2 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 CCH59248.1 - 0.00073 19.4 0.1 0.0097 15.8 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCH59248.1 - 0.0018 18.7 0.0 0.006 17.0 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Prothymosin PF03247.9 CCH59248.1 - 0.075 13.1 14.6 0.32 11.1 10.1 2.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family RNA_pol_N PF01194.12 CCH59249.1 - 2.5e-29 101.0 0.5 2.8e-29 100.9 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 CCH59249.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Chordopox_RPO7 PF05864.7 CCH59249.1 - 0.085 12.9 0.3 0.11 12.5 0.2 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.27 CCH59250.1 - 6.2e-07 29.0 0.3 9.3e-05 22.1 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat NAPRTase PF04095.11 CCH59251.1 - 2.6e-68 229.9 0.1 3.4e-68 229.5 0.1 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Y_phosphatase PF00102.22 CCH59252.1 - 1.5e-53 181.5 14.8 9.4e-52 175.6 1.3 3.1 3 1 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCH59252.1 - 0.0018 18.5 0.0 0.0064 16.7 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family RNA_pol_Rpb2_6 PF00562.23 CCH59253.1 - 8.5e-121 403.3 0.2 8.5e-121 403.3 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCH59253.1 - 3e-58 196.1 1.2 4.7e-58 195.4 0.8 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCH59253.1 - 1.7e-42 145.0 3.1 5.6e-42 143.3 2.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCH59253.1 - 4.2e-30 103.8 0.1 1.3e-29 102.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCH59253.1 - 3.5e-25 87.5 0.2 1.4e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCH59253.1 - 8.4e-19 67.0 0.0 1.8e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCH59253.1 - 1.2e-12 47.6 0.1 4.4e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 CCH59253.1 - 0.0014 17.0 0.1 0.0027 16.1 0.1 1.4 1 0 0 1 1 1 1 Baculovirus Y142 protein Phos_pyr_kin PF08543.7 CCH59254.1 - 4.1e-74 248.8 1.4 4.1e-74 248.8 1.0 1.4 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCH59254.1 - 1.5e-52 178.3 4.6 4e-52 177.0 1.5 2.1 2 0 0 2 2 2 1 TENA/THI-4/PQQC family PfkB PF00294.19 CCH59254.1 - 2.5e-07 30.1 0.0 3.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UPF0158 PF03682.8 CCH59254.1 - 0.022 14.3 0.1 0.062 12.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) DUF3885 PF13021.1 CCH59254.1 - 0.12 12.1 0.4 0.42 10.3 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Phos_pyr_kin PF08543.7 CCH59255.1 - 1.4e-61 207.8 0.1 2e-61 207.3 0.1 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCH59255.1 - 6.9e-52 176.2 0.4 9.6e-52 175.7 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CCH59255.1 - 4.7e-07 29.2 0.0 6.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Noc2 PF03715.8 CCH59256.1 - 3.1e-114 380.8 9.4 3.1e-114 380.8 6.5 2.4 3 0 0 3 3 3 1 Noc2p family RsbRD_N PF14361.1 CCH59256.1 - 0.0018 18.7 0.0 0.048 14.1 0.0 2.9 2 0 0 2 2 2 1 RsbT co-antagonist protein rsbRD N-terminal domain Tir_receptor_N PF07490.6 CCH59256.1 - 0.034 13.7 0.3 0.07 12.7 0.2 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus MMR_HSR1 PF01926.18 CCH59257.1 - 2.4e-09 37.1 0.7 8.9e-09 35.3 0.5 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCH59257.1 - 0.00062 19.6 0.4 0.012 15.4 0.0 2.8 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 CCH59257.1 - 0.00078 18.9 0.6 0.093 12.1 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCH59257.1 - 0.0036 16.5 0.0 0.007 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCH59257.1 - 0.033 13.4 0.0 0.093 12.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Ras PF00071.17 CCH59257.1 - 0.058 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.22 CCH59257.1 - 0.099 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CCH59257.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CCH59257.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 CCH59258.1 - 3.3e-46 156.8 0.0 1.3e-44 151.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59258.1 - 1.2e-27 95.5 0.2 2.9e-27 94.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCH59258.1 - 0.029 13.4 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CCH59258.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCH59258.1 - 0.095 11.0 0.0 0.25 9.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Mit_ribos_Mrp51 PF11709.3 CCH59259.1 - 1.5e-57 195.1 1.4 1.9e-57 194.8 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit SpoU_methylase PF00588.14 CCH59260.1 - 2.4e-27 95.5 0.1 2e-24 86.0 0.0 3.0 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CCH59260.1 - 2.6e-10 40.2 0.1 5.9e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF3336 PF11815.3 CCH59260.1 - 0.024 14.1 0.6 0.042 13.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) NUDIX PF00293.23 CCH59261.1 - 1.4e-22 79.7 0.0 2.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_C14 PF00656.17 CCH59263.1 - 6.4e-73 245.4 0.1 9.5e-73 244.9 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Radical_SAM PF04055.16 CCH59264.1 - 3.4e-15 56.6 0.0 6.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily RhoGAP PF00620.22 CCH59265.1 - 1.3e-25 89.7 0.1 1.3e-25 89.7 0.1 2.6 4 0 0 4 4 4 1 RhoGAP domain PX PF00787.19 CCH59265.1 - 1e-05 25.2 0.8 3.2e-05 23.6 0.6 1.9 1 0 0 1 1 1 1 PX domain PH PF00169.24 CCH59265.1 - 0.00071 19.7 0.2 0.00071 19.7 0.1 3.9 3 1 0 3 3 3 1 PH domain Sec2p PF06428.6 CCH59265.1 - 0.013 15.3 0.9 0.041 13.7 0.6 1.8 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Arginase PF00491.16 CCH59266.1 - 7.7e-71 238.6 0.0 8.7e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.12 CCH59267.1 - 3.3e-80 269.2 0.1 8.4e-80 267.9 0.0 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CCH59267.1 - 4.8e-28 97.3 13.3 2.9e-12 46.7 0.3 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCH59267.1 - 8.8e-20 70.2 1.5 1.2e-05 25.3 0.0 4.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCH59267.1 - 1.6e-19 69.8 2.3 2.6e-08 34.1 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.14 CCH59267.1 - 6.8e-19 68.7 14.3 6.8e-19 68.7 9.9 2.0 2 0 0 2 2 2 1 SPX domain Ank PF00023.25 CCH59267.1 - 2.3e-18 64.9 3.6 0.00043 19.9 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 CCH59267.1 - 2.1e-12 45.9 8.7 1.2 9.6 0.0 7.7 7 0 0 7 7 7 4 Ankyrin repeat CR6_interact PF10147.4 CCH59267.1 - 0.096 11.9 0.2 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Virul_fac_BrkB PF03631.10 CCH59267.1 - 0.13 11.6 0.1 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB ABC1 PF03109.11 CCH59268.1 - 2e-22 79.3 0.0 4.8e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 ABC1 family DUF3879 PF12995.2 CCH59270.1 - 0.085 12.4 0.1 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Pex24p PF06398.6 CCH59271.1 - 1.1e-24 86.8 24.5 4.8e-13 48.6 9.1 2.2 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin HSP70 PF00012.15 CCH59272.1 - 1.1e-178 594.9 1.8 2.6e-178 593.6 1.3 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH59272.1 - 2.4e-09 36.2 0.0 8.8e-09 34.3 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CCH59272.1 - 1.5e-06 28.0 0.8 0.00017 21.4 0.1 3.0 2 2 0 2 2 2 1 Cell division protein FtsA Trans_reg_C PF00486.23 CCH59272.1 - 0.15 11.9 0.5 0.96 9.4 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal Sec66 PF09802.4 CCH59273.1 - 1.2e-74 249.8 3.9 1.5e-74 249.5 2.7 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 GYF PF02213.11 CCH59274.1 - 1.2e-16 60.0 0.9 3.4e-16 58.5 0.6 1.9 1 0 0 1 1 1 1 GYF domain V_ATPase_I PF01496.14 CCH59274.1 - 2.1 6.0 19.5 3.7 5.2 13.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UMP1 PF05348.6 CCH59275.1 - 2.2e-33 114.9 0.1 3.4e-33 114.3 0.0 1.3 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.27 CCH59276.1 - 3.6e-31 105.8 13.4 8e-10 38.2 0.0 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 CCH59276.1 - 1.3e-07 31.5 0.1 5.5e-05 22.9 0.0 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CCH59276.1 - 0.0025 16.6 0.0 0.0074 15.1 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region PD40 PF07676.7 CCH59276.1 - 0.023 14.3 0.4 8.9 6.1 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.1 CCH59276.1 - 0.069 12.1 0.1 0.26 10.2 0.0 2.0 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Apc4_WD40 PF12894.2 CCH59276.1 - 0.098 12.1 0.0 4.1 7.0 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 CCH59276.1 - 0.12 10.5 0.3 0.27 9.2 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 tRNA-synt_2 PF00152.15 CCH59277.1 - 1.2e-103 346.4 0.4 2e-103 345.7 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCH59277.1 - 0.00011 21.9 0.4 0.00029 20.6 0.3 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCH59277.1 - 0.00047 19.7 0.5 0.0036 16.9 0.4 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CCH59277.1 - 0.0052 16.0 0.0 0.38 9.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DUF1033 PF06279.6 CCH59277.1 - 0.065 13.0 2.6 0.073 12.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) GCR1_C PF12550.3 CCH59277.1 - 0.2 11.5 4.2 0.16 11.8 0.1 2.5 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Pantoate_transf PF02548.10 CCH59278.1 - 1.5e-93 312.6 0.0 1.8e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CCH59278.1 - 1.3e-05 24.5 0.1 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PSP PF04046.11 CCH59278.1 - 0.072 12.4 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 PSP Lactamase_B_2 PF12706.2 CCH59279.1 - 1.7e-29 102.7 0.0 2.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCH59279.1 - 1.2e-09 38.0 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PAXNEB PF05625.6 CCH59280.1 - 3.1e-107 358.5 4.2 3.8e-107 358.2 2.9 1.0 1 0 0 1 1 1 1 PAXNEB protein Poty_PP PF08440.5 CCH59281.1 - 4.3e-05 22.7 3.8 0.0026 16.8 0.3 2.2 1 1 1 2 2 2 2 Potyviridae polyprotein K_trans PF02705.11 CCH59281.1 - 0.039 12.3 0.0 0.052 11.9 0.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter Peptidase_M56 PF05569.6 CCH59281.1 - 0.1 11.5 0.9 0.16 10.9 0.1 1.6 1 1 1 2 2 2 0 BlaR1 peptidase M56 CtIP_N PF10482.4 CCH59281.1 - 3.6 7.3 11.9 0.14 11.9 3.3 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain SieB PF14163.1 CCH59281.1 - 4.3 6.9 9.4 0.76 9.3 0.2 2.4 1 1 1 2 2 2 0 Superinfection exclusion protein B Abhydrolase_1 PF00561.15 CCH59282.1 - 6.5e-22 78.2 0.0 1.3e-21 77.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCH59282.1 - 1.2e-11 44.9 0.0 1.9e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH59282.1 - 5e-06 26.3 0.0 1.4e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCH59282.1 - 0.021 14.0 0.1 0.38 9.9 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 CCH59282.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) NOG1 PF06858.9 CCH59283.1 - 2.5e-27 94.5 0.4 5.9e-27 93.3 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 CCH59283.1 - 1.6e-26 91.7 3.7 1.6e-26 91.7 2.6 2.4 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 CCH59283.1 - 4.6e-16 58.8 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH59283.1 - 1.2e-07 31.1 0.0 2.6e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CCH59283.1 - 0.0005 19.2 0.2 0.001 18.2 0.1 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCH59283.1 - 0.0026 18.2 0.1 0.0085 16.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCH59283.1 - 0.36 10.6 4.9 10 5.9 0.0 3.2 3 1 1 4 4 4 0 Dynamin family AAA_23 PF13476.1 CCH59283.1 - 5.4 7.2 0.0 5.4 7.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain MFS_1 PF07690.11 CCH59284.1 - 3.9e-50 170.5 26.7 9.6e-48 162.6 6.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH59284.1 - 2.9e-20 72.3 29.6 4.1e-18 65.2 3.8 3.1 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 CCH59284.1 - 0.00053 18.2 16.5 0.052 11.6 6.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_2 PF13347.1 CCH59284.1 - 0.2 9.9 29.8 0.12 10.6 5.5 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein Ribosomal_S6e PF01092.14 CCH59285.1 - 3.4e-59 198.0 1.1 5.9e-59 197.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.13 CCH59286.1 - 1.2e-18 66.0 0.0 1.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) COPI_C PF06957.6 CCH59286.1 - 0.03 12.8 0.6 0.041 12.4 0.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Calpain_inhib PF00748.14 CCH59286.1 - 0.54 10.5 12.2 0.03 14.6 2.1 2.6 2 1 0 2 2 2 0 Calpain inhibitor Ceramidase PF05875.7 CCH59287.1 - 2e-84 282.8 26.0 2.3e-84 282.6 18.0 1.0 1 0 0 1 1 1 1 Ceramidase Radical_SAM PF04055.16 CCH59288.1 - 2.6e-15 57.0 0.1 6.8e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CCH59288.1 - 1.1e-12 47.8 0.1 3.3e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCH59288.1 - 0.091 12.9 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec16_C PF12931.2 CCH59289.1 - 1.3e-70 238.3 2.9 2.4e-70 237.5 2.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CCH59289.1 - 1.9e-17 63.3 0.0 1.9e-17 63.3 0.0 2.7 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region tRNA_int_end_N2 PF12928.2 CCH59290.1 - 2.2e-20 71.9 0.0 4.8e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Ribosomal_S4 PF00163.14 CCH59291.1 - 3.7e-27 94.5 1.7 5.3e-27 94.0 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCH59291.1 - 4.1e-13 48.5 2.0 4.5e-13 48.4 0.2 2.0 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.13 CCH59292.1 - 4.2e-45 151.5 5.8 6.2e-45 151.0 4.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e LRS4 PF10422.4 CCH59292.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Mito_carr PF00153.22 CCH59293.1 - 9.2e-77 252.8 2.2 3.7e-28 97.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GPI2 PF06432.6 CCH59294.1 - 1e-57 195.6 19.2 1.3e-57 195.3 13.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase GCR1_C PF12550.3 CCH59295.1 - 4e-21 74.6 0.4 9.5e-21 73.4 0.3 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes AAA PF00004.24 CCH59297.1 - 4.8e-39 133.5 0.1 2.2e-38 131.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH59297.1 - 1.4e-06 28.0 1.5 0.0039 16.9 0.0 3.5 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCH59297.1 - 7.7e-05 21.8 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCH59297.1 - 0.00071 19.7 4.0 0.0037 17.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.5 CCH59297.1 - 0.0022 17.8 0.0 0.0068 16.2 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.1 CCH59297.1 - 0.004 17.0 1.8 0.0099 15.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 CCH59297.1 - 0.0051 16.0 0.1 0.014 14.5 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CCH59297.1 - 0.0097 15.3 0.0 0.13 11.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH59297.1 - 0.017 14.8 0.2 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 CCH59297.1 - 0.031 13.7 0.4 0.13 11.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 CCH59297.1 - 0.18 12.5 4.1 0.47 11.2 0.0 3.5 2 1 0 3 3 3 0 AAA domain Glyco_transf_15 PF01793.11 CCH59298.1 - 3.3e-121 404.2 17.8 3.3e-121 404.2 12.4 1.7 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase tRNA_bind PF01588.15 CCH59299.1 - 1e-28 99.0 0.1 1.9e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain HR1 PF02185.11 CCH59299.1 - 0.13 11.9 2.2 0.2 11.4 0.5 2.1 2 0 0 2 2 2 0 Hr1 repeat NARP1 PF12569.3 CCH59299.1 - 2.9 6.5 10.3 4.3 5.9 7.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sugar_tr PF00083.19 CCH59300.1 - 2.1e-87 293.5 17.6 1.3e-86 290.9 12.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59300.1 - 1.4e-27 96.3 45.0 4.4e-25 88.1 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH59300.1 - 5.5e-06 24.8 3.3 5.5e-06 24.8 2.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 CCH59300.1 - 0.037 14.0 0.2 0.037 14.0 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) DUF1979 PF09322.5 CCH59300.1 - 0.053 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Oxidored_q1_N PF00662.15 CCH59300.1 - 0.08 12.5 0.7 0.2 11.2 0.5 1.7 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Lig_chan PF00060.21 CCH59300.1 - 0.12 12.0 1.5 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 Ligand-gated ion channel DUF1129 PF06570.6 CCH59300.1 - 0.84 8.9 3.7 3.2 7.0 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1129) Ribosomal_L18e PF00828.14 CCH59301.1 - 1.3e-34 119.3 0.2 1.7e-34 118.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Glycos_transf_4 PF00953.16 CCH59302.1 - 9.2e-30 103.5 12.7 9.2e-30 103.5 8.8 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 4 Phtf-FEM1B_bdg PF12129.3 CCH59302.1 - 0.14 11.5 0.3 0.31 10.4 0.2 1.6 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor DUF485 PF04341.7 CCH59302.1 - 7.2 6.3 8.0 1.6 8.4 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF485 WD40 PF00400.27 CCH59303.1 - 1.2e-37 126.4 14.4 2.6e-09 36.5 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Raptor_N PF14538.1 CCH59304.1 - 3.5e-65 218.5 0.4 3.9e-64 215.1 0.0 2.5 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain BBS2_Mid PF14783.1 CCH59304.1 - 4.4e-07 29.6 0.4 0.00015 21.4 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 CCH59304.1 - 5.8e-07 29.1 4.6 12 5.9 0.1 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT PF02985.17 CCH59304.1 - 1.6e-06 27.6 1.9 0.24 11.5 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 CCH59304.1 - 0.001 19.2 0.0 0.021 15.0 0.0 2.9 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 CCH59304.1 - 0.0049 16.7 2.0 0.23 11.3 0.7 3.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 DnaJ_CXXCXGXG PF00684.14 CCH59305.1 - 0.00024 21.0 6.5 0.18 11.8 0.9 2.5 2 0 0 2 2 2 2 DnaJ central domain DUF863 PF05904.6 CCH59305.1 - 0.77 7.9 14.7 0.87 7.7 10.2 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Macoilin PF09726.4 CCH59305.1 - 2.5 6.2 18.1 3.1 5.9 12.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 CCH59305.1 - 6.1 6.2 19.4 8.4 5.8 13.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF35_N PF12172.3 CCH59305.1 - 7.7 6.5 6.9 15 5.6 1.4 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Got1 PF04178.7 CCH59306.1 - 3.1e-20 72.4 11.4 3.7e-20 72.1 7.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 CCH59306.1 - 0.02 13.9 7.2 0.024 13.6 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF308 PF03729.8 CCH59306.1 - 5 7.2 16.8 2.7 8.0 8.7 2.6 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) PTR2 PF00854.16 CCH59307.1 - 1.5e-56 191.7 20.8 2.5e-56 191.0 14.4 1.4 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 CCH59307.1 - 1.6e-07 30.4 28.5 1.6e-07 30.4 19.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_15 PF01793.11 CCH59308.1 - 6.4e-125 416.4 8.8 6.4e-125 416.4 6.1 5.8 2 1 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase Zn_clus PF00172.13 CCH59309.1 - 2.3e-06 27.3 11.0 3.8e-06 26.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Iron_permease PF04120.7 CCH59310.1 - 1.4e-29 102.3 12.7 1.4e-14 53.8 0.3 5.4 5 0 0 5 5 5 5 Low affinity iron permease Toxin_R_bind_C PF07951.7 CCH59310.1 - 0.0084 15.8 0.8 0.33 10.6 0.0 2.5 2 0 0 2 2 2 1 Clostridium neurotoxin, C-terminal receptor binding DUF3589 PF12141.3 CCH59311.1 - 4.8e-94 315.3 8.5 1.5e-93 313.7 5.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) U79_P34 PF03064.11 CCH59311.1 - 3.5 7.0 21.3 8.8 5.7 14.8 1.7 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zip PF02535.17 CCH59311.1 - 9.5 5.1 6.9 16 4.3 4.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3589 PF12141.3 CCH59312.1 - 1.1e-88 297.6 3.0 3.8e-87 292.5 2.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) Prefoldin_2 PF01920.15 CCH59312.1 - 0.7 9.6 3.7 1.9 8.2 2.6 1.7 1 0 0 1 1 1 0 Prefoldin subunit DUF3589 PF12141.3 CCH59313.1 - 3.9e-85 285.9 1.2 8.2e-83 278.3 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) Zn_clus PF00172.13 CCH59314.1 - 3.1e-07 30.1 13.1 5.5e-07 29.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 CCH59315.1 - 9.7e-164 545.2 37.3 1.1e-163 545.0 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59315.1 - 4e-30 104.7 23.5 4e-30 104.7 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCH59315.1 - 0.00032 19.2 10.4 0.00032 19.2 7.2 3.0 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 CCH59315.1 - 0.006 14.7 6.1 0.008 14.3 2.0 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector ATP1G1_PLM_MAT8 PF02038.11 CCH59315.1 - 0.017 14.1 2.4 0.37 9.8 0.7 3.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PDR_CDR PF06422.7 CCH59315.1 - 2.8 7.6 0.0 2.8 7.6 0.0 3.4 4 0 0 4 4 4 0 CDR ABC transporter Transp_cyt_pur PF02133.10 CCH59316.1 - 1.9e-78 263.9 37.8 2.3e-78 263.7 26.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX7a PF02238.10 CCH59317.1 - 0.017 14.8 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Hat1_N PF10394.4 CCH59318.1 - 1.5e-32 112.9 6.3 1.5e-32 112.9 4.4 2.2 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_3 PF13302.1 CCH59318.1 - 0.0024 18.0 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCH59318.1 - 0.015 15.4 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCH59318.1 - 0.023 14.6 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCH59318.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.11 CCH59319.1 - 7.6e-52 175.6 0.0 8.4e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Kinetocho_Slk19 PF12709.2 CCH59320.1 - 0.23 11.5 1.8 7.8 6.6 0.3 2.6 2 0 0 2 2 2 0 Central kinetochore-associated Pil1 PF13805.1 CCH59321.1 - 2.1e-141 469.8 0.4 3.1e-141 469.2 0.3 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 CENP-T PF15511.1 CCH59321.1 - 0.32 10.1 28.9 0.58 9.3 20.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PPR_2 PF13041.1 CCH59322.1 - 2.4e-12 46.6 0.9 9.6e-07 28.6 0.1 3.7 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.1 CCH59322.1 - 3.8e-06 26.7 0.0 0.13 12.5 0.0 4.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCH59322.1 - 0.0098 15.3 0.3 5.4 6.5 0.0 3.8 4 0 0 4 4 4 1 PPR repeat HDA2-3 PF11496.3 CCH59323.1 - 9.8e-79 264.2 0.5 9.8e-79 264.2 0.3 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ThiF PF00899.16 CCH59324.1 - 6.3e-17 61.6 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.14 CCH59324.1 - 0.043 12.9 0.0 0.092 11.8 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sec23_trunk PF04811.10 CCH59325.1 - 5.5e-72 242.0 0.0 7.7e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCH59325.1 - 7.4e-35 118.4 0.1 1.7e-34 117.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCH59325.1 - 6.1e-30 103.5 1.2 1.3e-29 102.5 0.9 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCH59325.1 - 4.9e-13 48.3 11.0 8.6e-13 47.6 7.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCH59325.1 - 3.7e-12 45.7 0.0 8.9e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L5 PF00281.14 CCH59325.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L5 zf-MIZ PF02891.15 CCH59325.1 - 0.18 11.3 3.9 0.37 10.3 2.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PIG-U PF06728.8 CCH59326.1 - 2.4e-97 326.2 50.8 2.8e-97 326.0 35.2 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.17 CCH59328.1 - 6.5e-16 57.6 0.2 8.3e-16 57.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glycos_transf_2 PF00535.21 CCH59329.1 - 4.8e-26 91.4 0.0 9.6e-26 90.4 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CCH59329.1 - 3.9e-07 29.4 0.0 5.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CCH59329.1 - 2.5e-06 27.4 0.0 3.4e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATG13 PF10033.4 CCH59330.1 - 4.7e-53 180.0 9.5 2.1e-52 177.9 3.2 2.8 2 1 0 2 2 2 1 Autophagy-related protein 13 zf-C2H2 PF00096.21 CCH59331.1 - 6.5e-29 98.5 74.5 3e-05 24.0 1.9 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH59331.1 - 4.9e-27 92.2 67.8 6.4e-05 23.0 1.5 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH59331.1 - 8.8e-13 47.8 71.8 3.1e-05 24.0 1.9 9.8 10 0 0 10 10 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCH59331.1 - 1.1e-10 41.2 40.4 0.016 15.3 1.4 8.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCH59331.1 - 1.2e-08 34.8 40.9 0.023 14.8 1.0 9.0 9 1 0 9 9 9 5 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCH59331.1 - 2.2 8.4 45.4 7.3 6.7 10.4 6.0 2 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CCH59331.1 - 4.6 7.4 47.4 0.88 9.7 1.4 6.2 4 2 2 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding CpXC PF14353.1 CCH59331.1 - 9.7 6.1 23.4 0.49 10.3 0.1 4.6 3 1 2 5 5 5 0 CpXC protein RNA_pol_Rpb6 PF01192.17 CCH59332.1 - 1.7e-23 82.0 0.2 3.4e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_7 PF13499.1 CCH59333.1 - 1.1e-11 44.6 0.7 6.8e-07 29.3 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCH59333.1 - 8.9e-11 40.7 0.7 4.7e-06 26.0 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CCH59333.1 - 2.1e-09 35.9 5.2 1.7e-05 23.8 0.2 4.3 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 CCH59333.1 - 3.8e-08 32.3 0.9 1.2e-05 24.4 0.1 3.9 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 CCH59333.1 - 0.00028 20.4 0.6 0.47 10.0 0.1 3.3 1 1 1 3 3 3 3 EF-hand domain pair OST-HTH PF12872.2 CCH59333.1 - 0.027 14.3 0.0 8.1 6.3 0.0 2.6 2 1 0 2 2 2 0 OST-HTH/LOTUS domain TPR_11 PF13414.1 CCH59334.1 - 2.8e-29 100.5 4.8 2e-05 24.1 0.0 11.9 6 4 7 14 14 14 9 TPR repeat TPR_2 PF07719.12 CCH59334.1 - 1.9e-24 83.5 0.2 0.031 14.1 0.0 14.9 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCH59334.1 - 2.4e-23 82.2 0.9 7.7e-07 29.3 0.0 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59334.1 - 2.3e-21 75.9 0.0 0.00016 22.2 0.0 8.9 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCH59334.1 - 8.6e-17 60.1 0.0 1.2 9.9 0.0 10.6 7 3 6 13 13 12 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCH59334.1 - 4.1e-14 51.4 8.5 0.037 13.6 0.0 11.4 13 1 0 13 13 13 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCH59334.1 - 3.9e-13 48.4 0.6 0.92 9.8 0.0 10.8 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCH59334.1 - 2.3e-12 46.6 7.5 0.062 13.2 0.2 9.5 8 4 3 11 11 11 3 Tetratricopeptide repeat Apc3 PF12895.2 CCH59334.1 - 1e-10 41.5 2.5 0.0006 19.9 0.0 7.6 7 2 1 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCH59334.1 - 2.9e-10 39.9 0.9 37 5.0 0.0 10.3 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCH59334.1 - 3.8e-09 35.6 14.4 0.21 11.4 0.0 11.0 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH59334.1 - 0.00052 19.6 3.2 30 4.7 0.0 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CCH59334.1 - 0.03 13.8 0.0 0.13 11.7 0.0 2.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.1 CCH59334.1 - 0.076 12.8 0.0 8.6 6.3 0.0 4.5 7 0 0 7 7 6 0 Tetratricopeptide repeat RNA_pol_Rpc82 PF05645.8 CCH59335.1 - 7.6e-61 205.8 2.6 1.2e-60 205.1 1.8 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CCH59335.1 - 4.4e-20 71.3 6.0 1.6e-17 63.0 0.2 3.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CCH59335.1 - 1.7e-08 33.9 5.1 4e-07 29.5 0.1 3.8 4 0 0 4 4 4 1 TFIIE alpha subunit Penicillinase_R PF03965.11 CCH59335.1 - 0.0043 17.1 0.5 3.7 7.6 0.0 2.9 3 0 0 3 3 3 2 Penicillinase repressor DsrD PF08679.6 CCH59335.1 - 0.0093 15.9 1.8 0.35 10.9 0.3 3.2 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) HTH_24 PF13412.1 CCH59335.1 - 0.011 15.0 1.8 0.29 10.5 0.0 3.3 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding Cwf_Cwc_15 PF04889.7 CCH59335.1 - 0.022 14.5 3.2 0.046 13.4 2.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 CCH59335.1 - 0.66 8.6 7.6 1.1 7.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Plasmid_parti PF01672.11 CCH59335.1 - 3.8 8.0 10.0 0.46 10.9 0.3 3.4 3 0 0 3 3 3 0 Putative plasmid partition protein Peptidase_M16 PF00675.15 CCH59336.1 - 2.2e-20 72.9 0.0 3.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCH59336.1 - 1.2e-07 31.6 0.1 6.1e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Aa_trans PF01490.13 CCH59337.1 - 1.3e-30 106.2 38.9 1.6e-30 105.9 27.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3883 PF13020.1 CCH59337.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) PLA2_B PF01735.13 CCH59338.1 - 2.7e-191 636.0 4.0 2.7e-191 636.0 2.7 1.6 2 0 0 2 2 2 1 Lysophospholipase catalytic domain SMI1_KNR4 PF09346.5 CCH59338.1 - 0.035 14.1 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) DEAD PF00270.24 CCH59339.1 - 7.1e-53 178.5 0.2 1.4e-50 171.0 0.0 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59339.1 - 1e-30 105.4 0.0 7.7e-29 99.3 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH59339.1 - 5.7e-09 36.0 0.0 5.7e-09 36.0 0.0 3.0 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCH59339.1 - 0.0023 16.4 1.7 0.0023 16.4 1.2 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF1253) CMS1 PF14617.1 CCH59339.1 - 0.0031 16.6 0.0 0.0031 16.6 0.0 3.5 2 2 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit SR-25 PF10500.4 CCH59339.1 - 2.6 7.4 23.6 5.8 6.3 16.4 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BLVR PF06375.6 CCH59339.1 - 7 6.4 27.6 18 5.1 19.1 1.7 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NARP1 PF12569.3 CCH59339.1 - 9 4.9 23.0 20 3.7 15.9 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 KxDL PF10241.4 CCH59340.1 - 0.00031 20.5 0.5 0.0006 19.6 0.4 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein Cwf_Cwc_15 PF04889.7 CCH59340.1 - 0.029 14.0 2.4 0.048 13.3 1.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SHOCT PF09851.4 CCH59340.1 - 0.068 12.6 1.4 0.44 10.0 0.0 2.7 3 0 0 3 3 3 0 Short C-terminal domain Adaptin_N PF01602.15 CCH59341.1 - 2.5e-86 290.1 35.0 3.9e-86 289.4 24.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCH59341.1 - 0.00057 20.1 0.0 2.2 8.6 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 CCH59341.1 - 0.0022 17.9 0.3 11 6.4 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Barstar PF01337.13 CCH59341.1 - 0.021 14.6 0.0 0.078 12.8 0.0 2.0 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Med19 PF10278.4 CCH59341.1 - 1.2 8.8 32.7 36 3.9 21.3 3.1 2 1 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 NUFIP1 PF10453.4 CCH59342.1 - 8.6e-13 47.5 5.4 9.1e-13 47.5 0.7 3.2 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF544 PF04424.8 CCH59343.1 - 2.5e-27 95.0 0.0 5.4e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF544) RRM_1 PF00076.17 CCH59345.1 - 3.5e-09 36.1 0.1 1.1e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59345.1 - 3.9e-06 26.7 0.0 9.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59345.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CCH59346.1 - 8.5e-21 74.2 0.3 1.7e-20 73.2 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59346.1 - 2.6e-12 46.3 0.0 4.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59346.1 - 0.0075 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ClpB_D2-small PF10431.4 CCH59346.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein MBOAT PF03062.14 CCH59347.1 - 3.8e-58 197.1 23.9 3.8e-58 197.1 16.6 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.12 CCH59348.1 - 1.2e-23 83.4 0.0 2.2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.8 CCH59349.1 - 4.6e-19 68.0 15.3 4.6e-19 68.0 10.6 3.0 1 1 2 3 3 3 2 Mitotic checkpoint protein DUF1633 PF07794.6 CCH59349.1 - 0.053 11.4 4.9 0.11 10.4 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1633) SAP PF02037.22 CCH59349.1 - 0.14 11.6 0.2 0.14 11.6 0.1 2.7 3 0 0 3 3 3 0 SAP domain NAD_kinase PF01513.16 CCH59350.1 - 2.8e-51 174.0 0.0 3.7e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CCH59350.1 - 0.069 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MF_alpha_N PF05436.6 CCH59351.1 - 6.7e-22 76.9 0.4 9.7e-22 76.4 0.3 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 CCH59351.1 - 5.2e-14 51.4 22.0 0.086 13.0 0.2 5.3 5 0 0 5 5 5 5 Yeast mating factor alpha hormone DUF58 PF01882.13 CCH59351.1 - 0.0049 16.9 4.1 2.7 8.1 0.7 3.5 1 1 2 3 3 3 3 Protein of unknown function DUF58 DUF3423 PF11903.3 CCH59351.1 - 0.18 11.6 7.4 1.3e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3423) RRM_6 PF14259.1 CCH59353.1 - 6.1e-30 103.0 0.8 5.3e-07 29.5 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH59353.1 - 1.9e-26 91.4 0.2 2.3e-07 30.3 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59353.1 - 1.2e-25 89.0 2.8 2.2e-08 33.8 0.3 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCH59353.1 - 0.0022 17.8 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif SR-25 PF10500.4 CCH59353.1 - 0.02 14.4 3.8 0.038 13.4 2.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RIG-I_C-RD PF11648.3 CCH59353.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 C-terminal domain of RIG-I XLF PF09302.6 CCH59354.1 - 1.1e-05 25.2 8.5 2.4e-05 24.1 5.9 1.5 1 0 0 1 1 1 1 XLF (XRCC4-like factor) PBP1_TM PF14812.1 CCH59354.1 - 7.5 6.9 14.5 0.88 9.9 5.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spc7 PF08317.6 CCH59355.1 - 3e-26 91.8 29.1 3e-26 91.8 20.2 3.1 2 1 0 2 2 2 1 Spc7 kinetochore protein Spc7_N PF15402.1 CCH59355.1 - 0.31 9.0 41.8 0.0066 14.5 6.5 3.1 1 1 1 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Ribosomal_L36 PF00444.13 CCH59356.1 - 1.1e-19 70.0 9.5 1.7e-19 69.4 6.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 DUF3514 PF12027.3 CCH59356.1 - 0.028 13.6 0.7 0.032 13.4 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3514) Crust_neurohorm PF01147.12 CCH59356.1 - 0.033 13.4 2.1 0.036 13.3 0.9 1.5 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family UCH_1 PF13423.1 CCH59357.1 - 9.3e-37 127.0 11.5 9.6e-36 123.7 8.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CCH59357.1 - 2e-19 70.4 0.0 4.5e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease Metallophos PF00149.23 CCH59358.1 - 1.9e-39 135.1 0.1 3.4e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1399 PF07173.7 CCH59359.1 - 0.049 13.9 0.3 0.11 12.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1399) IL34 PF15036.1 CCH59360.1 - 0.01 15.4 0.6 0.02 14.4 0.4 1.5 1 0 0 1 1 1 1 Interleukin 34 Podoplanin PF05808.6 CCH59360.1 - 0.65 9.5 6.0 0.21 11.1 1.9 1.8 1 1 1 2 2 2 0 Podoplanin IncA PF04156.9 CCH59360.1 - 4.5 6.8 15.1 0.086 12.4 2.6 2.2 2 0 0 2 2 2 0 IncA protein RNA_POL_M_15KD PF02150.11 CCH59361.1 - 1.2e-15 56.8 3.2 1.2e-15 56.8 2.2 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CCH59361.1 - 6.3e-15 54.5 14.4 1e-13 50.6 1.2 3.1 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 CCH59361.1 - 0.0014 18.9 2.6 0.015 15.6 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Rubredoxin PF00301.15 CCH59361.1 - 0.011 15.5 4.3 9.2 6.2 0.1 3.9 4 0 0 4 4 4 0 Rubredoxin DZR PF12773.2 CCH59361.1 - 0.012 15.3 7.3 0.45 10.3 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Cytochrom_NNT PF03264.9 CCH59361.1 - 0.074 12.4 0.3 0.074 12.4 0.2 1.9 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Zn_Tnp_IS1595 PF12760.2 CCH59361.1 - 0.11 12.3 10.1 3.2 7.6 2.2 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.7 CCH59361.1 - 0.22 11.5 9.9 0.75 9.8 0.6 2.9 2 1 0 2 2 2 0 TFIIH C1-like domain zf-UBP PF02148.14 CCH59361.1 - 0.35 11.0 4.5 2.2 8.4 0.3 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein IBR PF01485.16 CCH59361.1 - 0.49 10.2 6.4 2.8 7.8 0.3 2.7 2 1 0 2 2 2 0 IBR domain zf-CHY PF05495.7 CCH59361.1 - 1.2 9.3 8.5 0.73 10.0 0.8 2.3 2 1 0 2 2 2 0 CHY zinc finger Rpr2 PF04032.11 CCH59361.1 - 1.4 8.8 4.9 48 3.9 3.4 2.5 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2296 PF10058.4 CCH59361.1 - 1.4 8.7 6.3 2 8.2 0.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Cytochrom_c3_2 PF14537.1 CCH59361.1 - 1.4 9.3 5.3 0.4 11.0 0.4 2.1 2 1 0 2 2 2 0 Cytochrome c3 ArfGap PF01412.13 CCH59361.1 - 1.5 8.6 4.6 3 7.6 0.6 2.3 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf zf-ribbon_3 PF13248.1 CCH59361.1 - 1.7 7.9 9.8 0.68 9.2 0.1 3.4 4 0 0 4 4 4 0 zinc-ribbon domain DUF3795 PF12675.2 CCH59361.1 - 3.4 7.9 6.3 74 3.6 4.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Zn-ribbon_8 PF09723.5 CCH59361.1 - 5.1 7.1 13.4 9.9 6.2 0.2 4.0 3 1 1 4 4 4 0 Zinc ribbon domain HypA PF01155.14 CCH59361.1 - 7.8 6.2 7.2 25 4.5 2.9 2.7 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1272 PF06906.6 CCH59361.1 - 7.9 6.4 8.0 3.8 7.4 0.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1272) Ribosomal_L12 PF00542.14 CCH59362.1 - 1.8e-20 72.6 6.9 1.8e-20 72.6 4.8 2.1 2 1 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain GCIP PF13324.1 CCH59362.1 - 0.0073 15.5 4.1 0.028 13.6 2.9 1.8 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Val_tRNA-synt_C PF10458.4 CCH59362.1 - 0.94 9.6 5.9 2.3 8.3 0.0 3.4 2 2 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Pkinase PF00069.20 CCH59363.1 - 3e-41 141.2 0.0 8.4e-41 139.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59363.1 - 2.3e-14 53.1 0.0 4.6e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH59363.1 - 0.088 12.5 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Androgen_recep PF02166.11 CCH59363.1 - 3.8 6.2 6.8 5.6 5.7 4.7 1.1 1 0 0 1 1 1 0 Androgen receptor HCO3_cotransp PF00955.16 CCH59363.1 - 4.9 5.6 5.0 9.3 4.7 3.5 1.3 1 0 0 1 1 1 0 HCO3- transporter family POX PF07526.6 CCH59363.1 - 7.2 6.8 11.2 7 6.8 4.4 2.4 2 0 0 2 2 2 0 Associated with HOX NUDIX PF00293.23 CCH59364.1 - 3.9e-11 42.7 0.0 6.9e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 CCH59364.1 - 0.00097 19.4 0.0 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 CCH59364.1 - 0.00098 18.5 0.1 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain TerY-C PF15616.1 CCH59364.1 - 0.029 14.3 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain GFA PF04828.9 CCH59364.1 - 0.088 12.7 0.2 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme GDPD PF03009.12 CCH59365.1 - 3.3e-23 82.4 0.1 8.4e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SCA7 PF08313.7 CCH59366.1 - 3e-33 113.2 2.5 3e-33 113.2 1.7 3.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain CDC27 PF09507.5 CCH59366.1 - 0.007 15.6 26.1 0.007 15.6 18.1 4.1 3 1 1 4 4 4 1 DNA polymerase subunit Cdc27 Glycos_transf_1 PF00534.15 CCH59367.1 - 5.5e-36 123.5 0.1 9.3e-36 122.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCH59367.1 - 5.7e-07 29.4 0.0 2e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CCH59367.1 - 5.2e-05 23.4 0.0 0.0011 19.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Radical_SAM PF04055.16 CCH59368.1 - 6.9e-24 84.8 0.0 2e-23 83.4 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 CCH59368.1 - 2.5e-21 75.5 0.0 6e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 CCH59368.1 - 6e-12 45.7 0.0 2.1e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin RVT_2 PF07727.9 CCH59369.1 - 6.3e-36 123.5 0.3 2.2e-35 121.7 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCH59369.1 - 7.2e-16 58.3 0.0 1.7e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tubulin-binding PF00418.14 CCH59369.1 - 0.025 14.2 0.1 0.13 11.9 0.0 2.2 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat PAP2 PF01569.16 CCH59370.1 - 3.9e-17 62.1 3.1 8.3e-17 61.0 2.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 CCH59370.1 - 0.093 13.0 2.3 0.31 11.3 1.6 1.9 1 0 0 1 1 1 0 PAP2 superfamily C-terminal APS_kinase PF01583.15 CCH59372.1 - 5.4e-72 240.5 0.0 6.4e-72 240.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 CCH59372.1 - 3.4e-06 27.8 0.2 6.6e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH59372.1 - 4e-06 26.7 0.0 7.9e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH59372.1 - 3.2e-05 24.2 0.2 7e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCH59372.1 - 0.00011 21.5 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CCH59372.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCH59372.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.3 1 1 0 1 1 1 1 ABC transporter CbiA PF01656.18 CCH59372.1 - 0.0019 17.6 0.0 0.0022 17.4 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 CCH59372.1 - 0.0073 16.6 1.0 0.011 16.0 0.7 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCH59372.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.6 1 1 1 2 2 2 1 Thymidylate kinase AAA_26 PF13500.1 CCH59372.1 - 0.011 15.3 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CCH59372.1 - 0.019 14.3 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.1 CCH59372.1 - 0.022 14.7 2.2 0.033 14.1 1.5 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCH59372.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CCH59372.1 - 0.063 13.2 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CCH59372.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCH59372.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CCH59372.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PAP2 PF01569.16 CCH59373.1 - 1.4e-10 40.9 2.0 1.4e-10 40.9 1.4 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCH59373.1 - 0.00016 21.2 2.5 0.00016 21.2 1.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily SNARE PF05739.14 CCH59374.1 - 0.0025 17.4 2.5 0.003 17.2 1.8 1.1 1 0 0 1 1 1 1 SNARE domain DUF1043 PF06295.7 CCH59374.1 - 0.008 15.8 0.4 0.0089 15.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) Use1 PF09753.4 CCH59374.1 - 0.021 14.2 0.6 0.023 14.1 0.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Hormone_1 PF00103.15 CCH59374.1 - 0.036 13.3 0.2 0.042 13.1 0.2 1.1 1 0 0 1 1 1 0 Somatotropin hormone family DUF1664 PF07889.7 CCH59374.1 - 0.04 13.7 0.6 0.051 13.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LETM1 PF07766.8 CCH59374.1 - 0.086 11.8 1.1 0.099 11.6 0.8 1.1 1 0 0 1 1 1 0 LETM1-like protein CK2S PF15011.1 CCH59374.1 - 0.11 12.2 0.2 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF3552 PF12072.3 CCH59374.1 - 0.13 11.5 0.6 0.15 11.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Corona_S2 PF01601.11 CCH59374.1 - 0.18 9.8 1.4 0.2 9.7 1.0 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein MitMem_reg PF13012.1 CCH59374.1 - 0.22 11.6 2.5 0.31 11.1 1.8 1.3 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function UPF0184 PF03670.8 CCH59374.1 - 0.53 10.5 4.6 2.1 8.5 1.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF4492 PF14899.1 CCH59374.1 - 0.84 9.1 3.7 0.54 9.7 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) F-actin_cap_A PF01267.12 CCH59375.1 - 3e-75 252.7 3.1 3.4e-75 252.5 2.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit VHS PF00790.14 CCH59376.1 - 8.2e-31 106.5 1.8 2.7e-30 104.8 1.2 1.9 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 CCH59376.1 - 7.7e-16 57.2 0.0 1.9e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCH59376.1 - 2.6e-15 55.6 0.0 5.3e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCH59376.1 - 1.4e-13 50.2 0.0 3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TRAM_LAG1_CLN8 PF03798.11 CCH59377.1 - 4.3e-33 114.5 23.1 4.3e-33 114.5 16.0 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCH59377.1 - 6.2e-19 67.2 1.9 1.4e-18 66.0 1.3 1.7 1 0 0 1 1 1 1 TRAM1-like protein Ribosomal_L10 PF00466.15 CCH59378.1 - 2.6e-17 62.5 0.0 4.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3538 PF12057.3 CCH59378.1 - 0.046 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) CENP-C_C PF11699.3 CCH59379.1 - 5.9e-24 83.8 3.0 1.6e-23 82.4 2.0 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 CCH59379.1 - 4.7e-15 56.3 9.3 4.7e-15 56.3 6.4 4.8 3 2 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 CCH59379.1 - 9.2e-05 21.8 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 CCH59379.1 - 0.018 14.6 0.1 0.056 13.0 0.0 1.8 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CRAL_TRIO PF00650.15 CCH59380.1 - 6.2e-37 126.5 0.1 1.1e-36 125.7 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH59380.1 - 9.3e-12 44.9 5.8 1.1e-11 44.6 2.2 2.5 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCH59380.1 - 0.0034 17.2 0.1 0.0064 16.3 0.1 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 CCH59381.1 - 4.3e-42 144.0 8.6 4.3e-42 144.0 6.0 2.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CCH59381.1 - 0.0066 16.2 0.1 0.0066 16.2 0.1 2.5 2 0 0 2 2 2 1 C2 domain UPF1_Zn_bind PF09416.5 CCH59382.1 - 3.4e-69 231.2 6.9 3.4e-69 231.2 4.8 2.1 3 0 0 3 3 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CCH59382.1 - 2.4e-58 196.8 0.0 6.9e-58 195.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCH59382.1 - 1.9e-53 181.5 1.8 3.5e-53 180.6 1.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCH59382.1 - 2.1e-14 53.5 0.1 6.4e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH59382.1 - 6.5e-13 48.2 0.0 2.5e-12 46.3 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 CCH59382.1 - 8.5e-07 28.9 0.0 2.4e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CCH59382.1 - 8.1e-05 21.7 1.1 0.00034 19.7 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CCH59382.1 - 0.00034 20.2 0.0 0.41 10.1 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CCH59382.1 - 0.0021 17.7 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 CCH59382.1 - 0.0045 15.9 0.1 2.3 7.0 0.0 2.6 3 0 0 3 3 3 2 PIF1-like helicase PhoH PF02562.11 CCH59382.1 - 0.0048 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 CCH59382.1 - 0.013 14.9 0.1 0.028 13.9 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 CCH59382.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CCH59382.1 - 0.042 13.8 1.4 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CCH59382.1 - 0.082 13.1 0.4 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH59382.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 CCH59382.1 - 0.12 12.1 0.3 0.33 10.7 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain zf-BED PF02892.10 CCH59382.1 - 0.16 11.7 5.1 0.34 10.7 1.9 2.9 2 0 0 2 2 2 0 BED zinc finger Abhydrolase_1 PF00561.15 CCH59383.1 - 1.1e-21 77.4 0.0 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCH59383.1 - 4.2e-21 75.2 0.0 3.1e-20 72.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH59383.1 - 3.5e-17 63.0 0.0 4.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCH59383.1 - 1.2e-11 44.3 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CCH59383.1 - 4.6e-06 26.0 0.0 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CCH59383.1 - 0.00019 20.4 0.1 0.014 14.2 0.0 2.5 2 1 0 2 2 2 1 Chlorophyllase enzyme FSH1 PF03959.8 CCH59383.1 - 0.00072 19.0 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Chlorophyllase PF07224.6 CCH59383.1 - 0.018 13.8 0.1 0.64 8.7 0.0 2.4 2 1 0 2 2 2 0 Chlorophyllase DLH PF01738.13 CCH59383.1 - 0.033 13.4 0.1 2.7 7.2 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF2305 PF10230.4 CCH59383.1 - 0.034 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 CCH59383.1 - 0.055 13.0 0.1 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 CCH59383.1 - 0.071 12.5 0.0 0.097 12.0 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DUF572 PF04502.8 CCH59384.1 - 6.3e-48 163.6 18.6 9.6e-48 163.0 12.9 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF572) E6 PF00518.12 CCH59384.1 - 0.018 15.3 0.2 0.043 14.1 0.1 1.6 1 0 0 1 1 1 0 Early Protein (E6) Peptidase_A22B PF04258.8 CCH59387.1 - 3.5e-61 207.2 9.4 8.8e-61 205.9 6.5 1.7 1 1 0 1 1 1 1 Signal peptide peptidase Macro_2 PF14519.1 CCH59389.1 - 6.1e-69 232.2 0.0 7e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Ribophorin_II PF05817.9 CCH59390.1 - 9.8e-09 33.9 3.4 1.3e-08 33.6 2.4 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II UNC-50 PF05216.8 CCH59390.1 - 0.0044 16.2 1.3 1.3 8.1 0.4 2.5 2 0 0 2 2 2 2 UNC-50 family DUF1240 PF06836.7 CCH59390.1 - 0.073 13.2 1.7 0.26 11.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Peptidase_S24 PF00717.18 CCH59392.1 - 1e-08 34.7 0.1 1.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCH59392.1 - 0.037 13.5 0.0 0.064 12.7 0.0 1.5 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 TrkA_N PF02254.13 CCH59393.1 - 0.0033 17.4 0.2 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 TrkA-N domain adh_short PF00106.20 CCH59393.1 - 0.0043 16.9 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase ParG PF09274.5 CCH59393.1 - 0.015 15.1 0.4 0.037 13.9 0.3 1.8 1 1 0 1 1 1 0 ParG Rep_fac_C PF08542.6 CCH59393.1 - 0.055 13.4 0.8 0.38 10.7 0.6 2.4 1 1 1 2 2 2 0 Replication factor C C-terminal domain AAA_14 PF13173.1 CCH59393.1 - 1 9.2 5.3 3 7.7 3.4 2.0 1 1 1 2 2 2 0 AAA domain LUC7 PF03194.10 CCH59394.1 - 7e-62 209.2 7.1 1.7e-59 201.3 4.9 2.0 1 1 0 1 1 1 1 LUC7 N_terminus ALMT PF11744.3 CCH59394.1 - 0.027 13.1 2.9 0.036 12.7 2.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF155 PF02582.9 CCH59394.1 - 0.041 13.8 3.6 0.077 12.8 2.5 1.4 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 DUF1202 PF06717.6 CCH59394.1 - 0.11 11.7 5.3 0.11 11.7 1.8 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1202) DUF2533 PF10752.4 CCH59394.1 - 0.27 11.5 3.3 0.82 10.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) IBD PF10416.4 CCH59394.1 - 0.81 9.4 8.1 0.15 11.8 1.3 2.6 2 1 1 3 3 3 0 Transcription-initiator DNA-binding domain IBD Nup35_RRM PF05172.8 CCH59395.1 - 4.3e-34 116.2 0.0 1.1e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCH59395.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SRP14 PF02290.10 CCH59396.1 - 1.1e-19 70.1 0.8 1.1e-19 70.1 0.6 2.0 2 1 0 2 2 2 1 Signal recognition particle 14kD protein Egg_lysin PF01303.12 CCH59396.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Egg lysin (Sperm-lysin) Haem_bd PF14376.1 CCH59396.1 - 0.076 12.7 0.6 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Haem-binding domain Nodulin-like PF06813.8 CCH59397.1 - 4.2e-09 36.0 6.6 4.2e-09 36.0 4.6 2.6 2 1 0 2 2 2 2 Nodulin-like RseC_MucC PF04246.7 CCH59397.1 - 6.9 6.2 11.5 15 5.1 0.3 3.9 4 0 0 4 4 4 0 Positive regulator of sigma(E), RseC/MucC PMT PF02366.13 CCH59398.1 - 4.3e-73 245.6 25.0 4.3e-73 245.6 17.3 2.6 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCH59398.1 - 7.3e-52 175.6 0.9 1e-51 175.1 0.6 1.2 1 0 0 1 1 1 1 MIR domain DUP PF00674.13 CCH59400.1 - 7.7e-13 48.3 4.8 7.7e-13 48.3 3.3 1.7 1 1 1 2 2 2 1 DUP family PFK PF00365.15 CCH59403.1 - 2e-167 555.2 3.1 1.9e-122 407.6 1.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 CCH59403.1 - 0.19 11.3 0.4 0.42 10.1 0.3 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif ANTH PF07651.11 CCH59404.1 - 7.3e-62 208.6 2.0 1.9e-61 207.2 1.4 1.7 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CCH59404.1 - 1.8e-07 31.0 1.7 2.8e-07 30.4 0.0 2.2 3 0 0 3 3 3 1 ENTH domain MPC PF03650.8 CCH59405.1 - 1.2e-45 154.3 0.1 1.2e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Porin_3 PF01459.17 CCH59406.1 - 1.3e-55 188.6 9.1 1.5e-55 188.4 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic porin COX4 PF02936.9 CCH59407.1 - 2.4e-36 124.5 0.1 2.8e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.3 CCH59407.1 - 0.065 13.6 5.1 0.041 14.2 2.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 CCH59407.1 - 0.2 11.1 2.1 1.9 8.0 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) COG5 PF10392.4 CCH59408.1 - 2.1e-32 111.8 9.6 2.1e-32 111.8 6.6 3.1 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Img2 PF05046.9 CCH59408.1 - 0.081 13.1 2.6 0.36 11.0 1.4 2.4 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) SPARC_Ca_bdg PF10591.4 CCH59408.1 - 0.23 11.5 1.4 0.86 9.6 0.3 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2011 PF09428.5 CCH59409.1 - 2.3e-18 66.3 15.6 2.9e-18 66.0 10.8 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) DUF148 PF02520.12 CCH59409.1 - 0.095 12.4 6.8 0.2 11.4 4.1 1.9 2 1 0 2 2 2 0 Domain of unknown function DUF148 DUF4584 PF15223.1 CCH59409.1 - 0.4 9.8 5.9 0.45 9.7 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) DivIC PF04977.10 CCH59409.1 - 5.8 6.4 11.3 2.8 7.4 0.9 2.8 2 1 1 3 3 3 0 Septum formation initiator Metallopep PF12044.3 CCH59410.1 - 2.2e-168 560.1 0.0 2.6e-168 559.8 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 CCH59410.1 - 1.3e-05 25.0 0.1 5.7e-05 23.0 0.0 2.0 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_3 PF13582.1 CCH59410.1 - 0.0046 17.4 0.2 0.0098 16.4 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CCH59410.1 - 0.021 14.9 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CCH59410.1 - 0.031 14.2 0.4 0.052 13.4 0.3 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 CCH59410.1 - 0.072 12.6 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Mob1_phocein PF03637.12 CCH59411.1 - 3e-71 238.7 0.6 3.9e-71 238.3 0.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glycos_transf_1 PF00534.15 CCH59412.1 - 3.6e-14 52.5 0.0 5.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCH59412.1 - 0.0033 17.5 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PH PF00169.24 CCH59413.1 - 6.3e-18 64.8 1.6 6.3e-18 64.8 1.1 2.6 2 0 0 2 2 2 1 PH domain DUF2722 PF10846.3 CCH59414.1 - 3.2e-24 85.7 19.4 1.3e-14 54.0 3.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2722) Pro_CA PF00484.14 CCH59415.1 - 5.9e-27 94.5 0.0 7.7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ODC_AZ PF02100.12 CCH59415.1 - 0.0095 15.4 0.0 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme CLTH PF10607.4 CCH59416.1 - 3.5e-23 81.9 6.1 3.5e-23 81.9 4.3 2.7 3 1 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain DUF3585 PF12130.3 CCH59416.1 - 0.047 13.5 1.0 0.084 12.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3585) Myb_DNA-binding PF00249.26 CCH59417.1 - 2.3e-07 30.7 0.0 6.7e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 CCH59418.1 - 1.5e-10 40.5 0.3 0.0001 22.0 0.2 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCH59418.1 - 0.032 13.0 0.6 3.2 6.4 0.1 2.7 1 1 1 2 2 2 0 Coatomer WD associated region BLVR PF06375.6 CCH59418.1 - 0.078 12.8 7.0 0.15 11.8 4.8 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RRP14 PF15459.1 CCH59418.1 - 0.26 11.3 10.0 0.58 10.2 6.9 1.6 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 Peptidase_S49_N PF08496.5 CCH59418.1 - 1.9 8.2 5.8 5.3 6.8 3.6 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 CCH59418.1 - 5.3 6.6 17.7 4.9 6.7 11.0 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Pkinase PF00069.20 CCH59419.1 - 7.1e-36 123.6 0.1 1.7e-35 122.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59419.1 - 2.6e-27 95.5 0.0 6.7e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59419.1 - 0.0074 15.2 0.0 0.015 14.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCH59419.1 - 0.21 11.2 0.0 2.1 8.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Iso_dh PF00180.15 CCH59420.1 - 7.5e-106 353.9 0.0 8.8e-106 353.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-NF-X1 PF01422.12 CCH59421.1 - 9.7e-12 44.6 154.4 2.1e-06 27.5 11.4 11.4 9 1 0 9 9 9 6 NF-X1 type zinc finger R3H PF01424.17 CCH59421.1 - 6.2e-10 38.6 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain MRP-S25 PF13741.1 CCH59422.1 - 2.6e-90 301.9 3.5 3e-90 301.7 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CCH59422.1 - 4.1e-07 29.9 0.5 9.6e-05 22.2 0.1 2.5 2 1 0 2 2 2 2 Mitochondrial ribosomal protein S23 DUF1253 PF06862.7 CCH59423.1 - 9.5e-159 528.5 16.1 1.8e-158 527.5 11.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) ICE2 PF08426.5 CCH59424.1 - 3e-138 460.9 38.1 3.5e-138 460.6 26.4 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.18 CCH59425.1 - 2e-15 56.4 4.8 2.4e-14 53.0 0.1 3.0 2 1 1 3 3 3 2 Cyclin, N-terminal domain Histone PF00125.19 CCH59426.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCH59426.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCH59426.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCH59426.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCH59427.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH59427.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCH59427.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCH59427.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCH59427.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCH59427.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCH59427.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCH59427.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_15 PF01793.11 CCH59428.1 - 2.3e-119 398.2 21.3 3.9e-119 397.4 14.8 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Tnp_P_element_C PF12596.3 CCH59428.1 - 0.077 13.3 1.2 0.18 12.1 0.9 1.6 1 0 0 1 1 1 0 87kDa Transposase Sds3 PF08598.6 CCH59429.1 - 3.4e-13 49.5 13.0 7.8e-13 48.4 9.0 1.6 1 1 0 1 1 1 1 Sds3-like Tup_N PF08581.5 CCH59429.1 - 0.57 10.4 9.5 1 9.6 3.3 2.9 2 0 0 2 2 2 0 Tup N-terminal Met_10 PF02475.11 CCH59430.1 - 1.9e-09 37.4 0.0 4.2e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 CCH59430.1 - 0.0021 17.4 0.0 0.0073 15.7 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 DUF3263 PF11662.3 CCH59430.1 - 0.005 16.2 0.1 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3263) Methyltransf_26 PF13659.1 CCH59430.1 - 0.046 13.7 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCH59430.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain zf-H2C2_2 PF13465.1 CCH59431.1 - 5.3e-14 51.7 7.6 1.1e-07 31.7 0.3 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCH59431.1 - 4.9e-12 45.4 14.4 1.8e-06 27.9 1.0 4.3 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH59431.1 - 1.7e-11 43.6 10.0 0.00018 21.5 0.8 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CCH59431.1 - 2.6e-08 33.7 4.7 3.7e-05 23.7 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCH59431.1 - 1.4e-06 28.2 8.2 0.0013 18.8 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 CCH59431.1 - 0.0024 18.0 2.9 0.0024 18.0 2.0 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Endonuclease_7 PF02945.10 CCH59431.1 - 0.086 12.5 1.4 0.2 11.3 1.0 1.6 1 0 0 1 1 1 0 Recombination endonuclease VII zf-C2H2_6 PF13912.1 CCH59431.1 - 0.15 12.0 5.1 8.6 6.4 0.2 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHY PF05495.7 CCH59431.1 - 0.17 12.0 2.5 0.45 10.7 1.7 1.7 1 0 0 1 1 1 0 CHY zinc finger zf-BED PF02892.10 CCH59431.1 - 0.7 9.7 5.6 1.5 8.6 0.3 3.5 3 0 0 3 3 3 0 BED zinc finger C1_4 PF07975.7 CCH59431.1 - 2.3 8.2 4.7 37 4.4 3.2 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain Bac_surface_Ag PF01103.18 CCH59432.1 - 2.4e-43 148.8 14.4 2.4e-43 148.8 10.0 1.5 2 0 0 2 2 2 1 Surface antigen DFP PF04127.10 CCH59433.1 - 1.1e-14 54.5 0.0 1.5e-05 24.6 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein UCH PF00443.24 CCH59434.1 - 3e-42 144.5 22.7 7.9e-42 143.2 15.7 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH59434.1 - 5.2e-11 42.5 3.0 2.5e-06 27.1 0.3 3.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF1528 PF07515.6 CCH59434.1 - 0.64 10.0 6.4 0.73 9.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) ABC2_membrane_3 PF12698.2 CCH59435.1 - 0.019 13.9 0.3 0.024 13.6 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Spore_III_AF PF09581.5 CCH59435.1 - 0.046 13.5 3.2 0.11 12.3 0.0 2.0 1 1 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Inhibitor_I9 PF05922.11 CCH59436.1 - 6.2e-05 23.4 0.1 7.6e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 tRNA_anti_2 PF13742.1 CCH59436.1 - 0.039 13.8 0.1 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain Glyco_hydro_38 PF01074.17 CCH59437.1 - 7e-84 281.3 1.7 1.2e-83 280.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CCH59437.1 - 5e-64 216.7 4.5 7.3e-64 216.2 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CCH59437.1 - 1.3e-23 83.0 0.1 5.3e-23 81.0 0.0 2.1 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Prenyltrans PF00432.16 CCH59438.1 - 5.6e-34 115.3 3.6 6.2e-08 32.0 0.0 7.0 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCH59438.1 - 5.3e-21 75.1 0.0 1.1e-07 32.2 0.0 3.8 3 1 1 4 4 4 3 Prenyltransferase-like MDM31_MDM32 PF08118.6 CCH59439.1 - 1.1e-240 799.3 6.1 1.3e-240 799.1 4.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Glyco_hydro_47 PF01532.15 CCH59440.1 - 2.4e-133 445.1 2.7 2.9e-133 444.8 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Methyltransf_16 PF10294.4 CCH59441.1 - 1.8e-19 69.8 0.3 3.5e-19 68.9 0.1 1.5 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 CCH59441.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CCH59441.1 - 0.006 15.7 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2 PF00096.21 CCH59442.1 - 5.6e-08 32.6 12.9 0.00013 22.1 2.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCH59442.1 - 6.7e-06 26.1 9.7 2.4e-05 24.3 3.5 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCH59442.1 - 0.0023 18.1 13.3 0.054 13.8 2.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Dus PF01207.12 CCH59443.1 - 2.7e-79 266.2 0.0 3.7e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Cupin_5 PF06172.6 CCH59444.1 - 3e-37 127.6 0.0 3.9e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Peptidase_M28 PF04389.12 CCH59445.1 - 2.5e-09 37.1 0.0 5.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CCH59445.1 - 7.5e-08 32.0 0.0 2.4e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCH59445.1 - 0.0024 17.5 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Pro_isomerase PF00160.16 CCH59446.1 - 1.3e-48 165.1 0.2 1.4e-48 164.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 CCH59447.1 - 1.3e-31 109.0 0.6 2.1e-31 108.3 0.4 1.4 1 0 0 1 1 1 1 ENTH domain Sybindin PF04099.7 CCH59448.1 - 4.1e-20 71.9 0.8 5.5e-20 71.5 0.6 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CCH59448.1 - 0.0069 16.2 0.3 0.0079 16.0 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region EAP30 PF04157.11 CCH59448.1 - 0.068 12.3 0.0 0.083 12.0 0.0 1.0 1 0 0 1 1 1 0 EAP30/Vps36 family Ribosomal_L18p PF00861.17 CCH59448.1 - 0.14 12.3 0.1 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L18p/L5e family FKBP_C PF00254.23 CCH59450.1 - 6.6e-27 93.3 0.0 6.6e-27 93.3 0.0 2.3 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase SDA1 PF05285.7 CCH59450.1 - 0.24 10.6 61.0 0.048 12.9 13.9 2.2 2 0 0 2 2 2 0 SDA1 Utp11 PF03998.8 CCH59450.1 - 0.42 10.3 35.4 0.18 11.5 13.8 2.1 2 0 0 2 2 2 0 Utp11 protein GAGA_bind PF06217.7 CCH59450.1 - 4.1 7.2 26.4 0.79 9.6 2.3 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family GEMIN8 PF15348.1 CCH59450.1 - 4.9 7.1 31.5 1.8 8.5 5.5 2.2 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 AAA_11 PF13086.1 CCH59450.1 - 5.1 6.5 15.9 0.47 9.9 0.9 2.2 2 0 0 2 2 2 0 AAA domain Vfa1 PF08432.5 CCH59450.1 - 6.8 6.6 47.8 0.64 10.0 7.8 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 CCH59450.1 - 6.9 6.4 12.1 5.3 6.8 0.1 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.7 CCH59450.1 - 7.8 5.6 38.1 1.1 8.4 5.5 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Piwi PF02171.12 CCH59451.1 - 1.6e-67 227.6 0.7 2.9e-67 226.7 0.5 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCH59451.1 - 7.8e-11 41.4 0.3 2.6e-10 39.7 0.2 1.9 1 0 0 1 1 1 1 PAZ domain MIP-T3 PF10243.4 CCH59451.1 - 0.77 8.1 30.7 1.2 7.5 21.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 CCH59451.1 - 2.8 6.6 15.4 4.4 6.0 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Transformer PF06495.6 CCH59451.1 - 7.3 6.4 54.7 3.4 7.4 9.1 2.5 1 1 1 2 2 2 0 Fruit fly transformer protein Ribosomal_L6e PF01159.14 CCH59452.1 - 4e-40 136.4 2.1 6e-40 135.8 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Rax2 PF12768.2 CCH59452.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity C2 PF00168.25 CCH59453.1 - 8e-51 169.8 1.5 3.9e-18 65.0 0.0 4.7 4 0 0 4 4 4 4 C2 domain vATP-synt_AC39 PF01992.11 CCH59454.1 - 4e-81 272.7 1.2 4.6e-81 272.5 0.8 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Cyt-b5 PF00173.23 CCH59455.1 - 6e-08 32.3 0.2 1.3e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2362 PF10154.4 CCH59455.1 - 0.13 10.9 0.5 0.22 10.1 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Hexokinase_1 PF00349.16 CCH59456.1 - 2.1e-09 37.0 0.5 4.6e-09 35.9 0.3 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CCH59456.1 - 8.5e-07 28.4 0.0 1.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Hexokinase BAR PF03114.13 CCH59457.1 - 0.011 15.3 6.2 0.056 12.9 4.3 2.2 1 1 0 1 1 1 0 BAR domain CCD PF07860.6 CCH59457.1 - 0.049 13.1 0.2 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 WisP family C-Terminal Region Dak1 PF02733.12 CCH59458.1 - 3.7e-131 436.5 1.4 5.1e-131 436.0 1.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CCH59458.1 - 1.1e-44 152.1 0.3 2.6e-44 150.9 0.2 1.6 1 0 0 1 1 1 1 DAK2 domain HTH_7 PF02796.10 CCH59458.1 - 0.086 12.7 0.1 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase SSrecog PF03531.9 CCH59459.1 - 2.3e-66 223.3 2.9 2.9e-64 216.4 2.0 2.5 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CCH59459.1 - 7.2e-30 102.8 0.0 9.3e-28 96.0 0.0 3.2 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Helicase_IV_N PF12462.3 CCH59459.1 - 0.061 12.9 0.1 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal bPH_2 PF03703.9 CCH59459.1 - 0.11 12.5 0.0 47 4.0 0.0 3.3 3 0 0 3 3 3 0 Bacterial PH domain IBR PF01485.16 CCH59460.1 - 1.1e-11 44.4 45.5 2.7e-07 30.3 2.3 4.1 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CCH59460.1 - 6.8e-06 25.8 5.0 6.8e-06 25.8 3.5 4.6 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH59460.1 - 0.00057 19.8 7.3 0.00057 19.8 5.0 5.2 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF485 PF04341.7 CCH59462.1 - 1.4 8.6 4.7 2.4 7.9 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 COPIIcoated_ERV PF07970.7 CCH59463.1 - 4.1e-28 98.5 0.0 6.3e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCH59463.1 - 8.2e-15 54.5 0.1 1.7e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C2H2 PF00096.21 CCH59464.1 - 1.8e-09 37.3 12.8 0.00014 21.9 2.1 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCH59464.1 - 5.9e-06 26.3 11.7 2.9e-05 24.1 0.3 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCH59464.1 - 3.7e-05 23.7 14.4 0.0014 18.8 0.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger PRP21_like_P PF12230.3 CCH59464.1 - 0.062 12.7 0.4 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_jaz PF12171.3 CCH59464.1 - 0.62 10.2 4.6 0.49 10.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCH59464.1 - 0.67 10.2 7.6 0.16 12.2 1.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Malic_M PF03949.10 CCH59465.1 - 3.2e-75 253.0 0.1 5.7e-75 252.1 0.1 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCH59465.1 - 3.3e-63 212.5 0.2 3e-62 209.4 0.0 2.2 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 CCH59465.1 - 0.057 12.9 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 CCH59466.1 - 8.4e-38 129.2 0.0 1.5e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCH59466.1 - 9.1e-05 22.5 0.1 0.00019 21.5 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CCH59466.1 - 0.024 13.6 0.2 0.05 12.5 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 CCH59466.1 - 0.032 14.2 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 CCH59466.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_17 PF00332.13 CCH59466.1 - 0.094 11.7 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 NAD_binding_7 PF13241.1 CCH59466.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Mito_carr PF00153.22 CCH59467.1 - 8.3e-59 195.3 0.0 1e-20 73.2 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2370 PF10176.4 CCH59468.1 - 1.2e-72 244.0 0.0 1.2e-72 244.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) QCR10 PF09796.4 CCH59469.1 - 5.1e-23 80.5 0.2 6.5e-23 80.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CCH59469.1 - 0.16 11.6 0.8 0.25 11.0 0.6 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Oxysterol_BP PF01237.13 CCH59470.1 - 1.8e-90 303.0 0.7 2.3e-90 302.6 0.5 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Dynamin_M PF01031.15 CCH59471.1 - 5.4e-104 347.1 0.2 5.4e-104 347.1 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CCH59471.1 - 3.3e-55 186.4 0.4 3.3e-55 186.4 0.2 2.0 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CCH59471.1 - 7.9e-26 89.7 5.7 2.2e-25 88.3 3.9 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCH59471.1 - 0.00026 20.9 0.9 0.0051 16.7 0.6 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCH59471.1 - 0.011 16.1 0.1 0.042 14.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Ribosomal_L1 PF00687.16 CCH59472.1 - 9.4e-26 90.5 13.3 3.5e-25 88.6 9.2 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Prenyltransf PF01255.14 CCH59472.1 - 0.033 13.3 0.3 0.053 12.6 0.2 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase MAAL_C PF07476.6 CCH59472.1 - 0.068 12.0 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus RNA_pol_Rpb4 PF03874.11 CCH59473.1 - 9.8e-35 119.0 9.6 1.9e-34 118.1 6.6 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Pkinase PF00069.20 CCH59474.1 - 3.2e-51 173.9 0.1 7.2e-51 172.8 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59474.1 - 4.4e-22 78.4 0.0 7.8e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH59474.1 - 0.0042 16.8 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCH59474.1 - 0.0044 16.3 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family VirDNA-topo-I_N PF09266.5 CCH59474.1 - 0.054 13.3 0.5 0.33 10.8 0.2 2.3 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal CRAL_TRIO PF00650.15 CCH59476.1 - 5.9e-24 84.3 0.2 1.2e-23 83.4 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH59476.1 - 2.2e-07 30.9 1.0 6e-07 29.5 0.7 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RNA_polI_A34 PF08208.6 CCH59477.1 - 1.1e-35 123.1 27.2 1.1e-35 123.1 18.8 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Clathrin_lg_ch PF01086.12 CCH59480.1 - 7.2e-34 117.6 5.6 7.8e-34 117.5 3.9 1.0 1 0 0 1 1 1 1 Clathrin light chain MAP7 PF05672.6 CCH59480.1 - 0.017 14.5 4.5 0.02 14.2 3.1 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family PHA_synth_III_E PF09712.5 CCH59480.1 - 0.025 13.9 0.7 0.025 13.9 0.5 1.0 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Mistic PF11458.3 CCH59480.1 - 0.048 14.0 0.9 0.065 13.6 0.6 1.4 1 0 0 1 1 1 0 Membrane-integrating protein Mistic DUF883 PF05957.8 CCH59480.1 - 0.085 13.2 1.1 0.11 12.9 0.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF4521 PF15021.1 CCH59480.1 - 0.12 11.9 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Trs65 PF12735.2 CCH59481.1 - 1.3e-36 126.5 23.6 1.3e-36 126.5 16.4 1.8 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 SpoIIIAH PF12685.2 CCH59481.1 - 0.0089 15.5 3.2 0.02 14.3 2.2 1.5 1 0 0 1 1 1 1 SpoIIIAH-like protein Nop14 PF04147.7 CCH59481.1 - 0.014 13.4 9.1 0.022 12.6 6.3 1.3 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 CCH59481.1 - 0.12 11.9 7.3 0.2 11.1 5.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sigma70_ner PF04546.8 CCH59481.1 - 0.12 11.9 8.4 0.19 11.3 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 CCH59481.1 - 0.2 10.3 17.1 0.29 9.8 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 CCH59481.1 - 0.41 9.0 10.7 0.62 8.4 7.4 1.2 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 CCH59481.1 - 1.7 8.9 18.7 3.3 7.9 12.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.1 CCH59481.1 - 1.9 8.1 6.6 4.3 7.0 4.6 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.6 CCH59481.1 - 2.5 7.9 17.6 0.1 12.3 6.6 2.6 3 0 0 3 3 3 0 RXT2-like, N-terminal TMEM51 PF15345.1 CCH59481.1 - 3.8 7.1 6.1 1.5 8.4 2.2 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 NOA36 PF06524.7 CCH59481.1 - 4.5 6.4 11.9 7.2 5.7 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.3 CCH59481.1 - 7.5 6.4 21.1 1.5 8.7 11.9 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 EBV-NA3 PF05009.7 CCH59481.1 - 9.6 5.3 7.1 16 4.6 4.9 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Bot1p PF12298.3 CCH59482.1 - 3.2e-48 163.9 0.1 5e-48 163.2 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Sad1_UNC PF07738.8 CCH59483.1 - 1.1e-08 34.9 0.4 2.5e-07 30.5 0.0 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal NPV_P10 PF05531.7 CCH59483.1 - 0.83 9.9 7.5 8.8 6.6 0.5 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ING PF12998.2 CCH59483.1 - 1.4 9.2 11.8 0.036 14.3 1.8 3.0 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding UPF0118 PF01594.11 CCH59483.1 - 4.3 6.2 6.0 0.78 8.6 1.3 1.8 1 1 0 2 2 2 0 Domain of unknown function DUF20 Mad3_BUB1_I PF08311.7 CCH59485.1 - 9.1e-36 122.4 2.6 2.2e-35 121.1 1.8 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CCH59485.1 - 3.4e-25 87.7 0.8 1.6e-24 85.5 0.2 2.5 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 CCH59485.1 - 1.4e-18 67.0 0.3 3.6e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59485.1 - 3.3e-06 26.3 0.0 7.2e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59485.1 - 0.02 13.8 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like VTC PF09359.5 CCH59486.1 - 3.2e-104 347.9 0.1 5.4e-104 347.1 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 CCH59486.1 - 4.1e-23 82.5 15.0 2.5e-09 37.3 0.8 3.8 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.10 CCH59486.1 - 2.7e-09 37.1 4.2 6.5e-09 35.8 2.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) ASF1_hist_chap PF04729.8 CCH59487.1 - 2.1e-66 222.3 0.2 3.4e-66 221.6 0.2 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.5 CCH59487.1 - 0.003 16.7 45.1 0.0041 16.2 31.3 1.2 1 0 0 1 1 1 1 BUD22 UPF0154 PF03672.8 CCH59487.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) SUN PF03856.8 CCH59488.1 - 2.3e-101 338.2 20.9 3.9e-101 337.5 14.5 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DIM PF08194.7 CCH59488.1 - 0.1 12.5 0.8 3 7.8 0.0 2.8 2 0 0 2 2 2 0 DIM protein DUF916 PF06030.7 CCH59488.1 - 1.9 8.2 4.6 33 4.2 0.1 3.4 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF916) Macoilin PF09726.4 CCH59488.1 - 9.1 4.4 10.5 12 4.0 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein His_Phos_1 PF00300.17 CCH59489.1 - 2.5e-30 105.6 0.0 3.2e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CCH59489.1 - 5.6e-05 22.6 0.0 8.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) YqbF PF14553.1 CCH59489.1 - 0.02 14.5 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 YqbF, hypothetical protein domain MFS_Mycoplasma PF07672.8 CCH59490.1 - 0.014 14.5 0.3 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Mycoplasma MFS transporter Pho86 PF11124.3 CCH59491.1 - 1.2e-87 293.7 4.4 1.4e-87 293.5 3.0 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 DUF1212 PF06738.7 CCH59491.1 - 0.14 11.6 4.1 0.21 11.0 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF2570 PF10828.3 CCH59492.1 - 0.089 12.3 0.1 0.089 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Glyco_hydro_16 PF00722.16 CCH59493.1 - 2e-44 151.1 0.4 2e-44 151.1 0.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DUF936 PF06075.7 CCH59493.1 - 3.1 6.6 39.1 4 6.2 27.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF605 PF04652.11 CCH59493.1 - 4.1 6.6 32.0 5.8 6.1 22.2 1.2 1 0 0 1 1 1 0 Vta1 like DUF2146 PF10220.4 CCH59493.1 - 4.4 5.1 20.0 6.1 4.6 13.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Utp14 PF04615.8 CCH59493.1 - 6.4 4.8 23.0 8.2 4.4 15.9 1.0 1 0 0 1 1 1 0 Utp14 protein FAM196 PF15265.1 CCH59493.1 - 6.5 5.8 31.7 9 5.4 22.0 1.1 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.8 CCH59493.1 - 7.8 6.2 19.8 11 5.8 13.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 CCH59494.1 - 1.7e-10 41.0 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH59494.1 - 0.0025 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCH59494.1 - 0.016 15.0 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ribosomal_S10 PF00338.17 CCH59495.1 - 3.1e-27 94.2 0.9 3.6e-27 94.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF276 PF03434.8 CCH59495.1 - 0.052 12.5 0.3 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 DUF276 Lung_7-TM_R PF06814.8 CCH59496.1 - 1.1e-81 274.0 25.4 1.4e-81 273.6 17.6 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor NifU PF01106.12 CCH59497.1 - 6e-22 77.1 0.0 1.1e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CCH59497.1 - 1.3e-20 72.8 0.0 3.3e-20 71.4 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.4 CCH59497.1 - 0.005 16.6 1.1 0.011 15.5 0.8 1.6 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Adap_comp_sub PF00928.16 CCH59498.1 - 1.2e-59 201.5 1.2 2.9e-59 200.3 0.8 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Chitin_synth_2 PF03142.10 CCH59499.1 - 5.1e-283 939.2 0.0 7.2e-283 938.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCH59499.1 - 2.4e-16 60.0 0.8 8.6e-16 58.2 0.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCH59499.1 - 1e-14 54.9 0.0 2.8e-12 46.9 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CCH59499.1 - 3.3e-06 26.8 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCH59499.1 - 0.00083 19.0 0.0 0.022 14.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCH59499.1 - 0.0058 15.9 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 FAM195 PF14799.1 CCH59500.1 - 0.35 10.7 3.2 0.99 9.2 2.2 1.9 1 1 0 1 1 1 0 FAM195 family Nucleoporin2 PF04096.9 CCH59501.1 - 6e-36 123.3 3.3 3.4e-35 120.9 0.0 2.7 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCH59501.1 - 3.9e-29 101.1 340.6 1.2e-08 35.1 30.8 10.3 2 1 9 11 11 11 9 Nucleoporin FG repeat region Bac_rhodopsin PF01036.13 CCH59502.1 - 3.5e-55 186.7 17.3 4e-55 186.5 12.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCH59502.1 - 0.35 10.2 12.9 0.48 9.8 2.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) 7tm_7 PF08395.7 CCH59502.1 - 5.9 5.8 16.9 6.3 5.7 6.9 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor Retrotrans_gag PF03732.12 CCH59503.1 - 1e-10 41.5 0.0 5e-10 39.3 0.0 2.0 1 1 1 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCH59503.1 - 0.011 15.6 0.7 0.011 15.6 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle Peptidase_A2B PF12384.3 CCH59504.1 - 8.7e-12 44.7 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCH59504.1 - 2.3e-05 24.8 0.0 3.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CCH59504.1 - 0.00032 20.6 0.1 0.00058 19.8 0.1 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCH59504.1 - 0.00052 19.7 0.1 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CCH59505.1 - 2e-21 76.3 1.1 2.8e-21 75.8 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCH59506.1 - 1.1e-09 38.4 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain DUF3850 PF12961.2 CCH59506.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) SRF-TF PF00319.13 CCH59507.1 - 2.8e-25 87.2 0.3 5.2e-25 86.4 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PWWP PF00855.12 CCH59508.1 - 1.1e-17 63.9 0.1 5.7e-17 61.6 0.1 2.3 1 0 0 1 1 1 1 PWWP domain Bac_rhodopsin PF01036.13 CCH59509.1 - 3.1e-49 167.2 20.5 3.7e-49 167.0 14.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein BRI3BP PF14965.1 CCH59509.1 - 0.012 14.9 6.7 0.024 14.0 4.6 1.4 1 1 0 1 1 1 0 Negative regulator of p53/TP53 DUF4131 PF13567.1 CCH59509.1 - 0.12 11.8 7.4 0.77 9.1 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Bac_rhodopsin PF01036.13 CCH59510.1 - 1.4e-49 168.4 17.5 1.6e-49 168.2 12.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCH59510.1 - 0.0022 17.4 9.6 0.43 9.9 3.4 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4131) Glyco_hydro_15 PF00723.16 CCH59511.1 - 9.3e-57 192.5 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Iso_dh PF00180.15 CCH59512.1 - 4e-77 259.5 0.1 4.5e-77 259.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2431 PF10354.4 CCH59513.1 - 1.6e-56 190.8 1.7 1.6e-56 190.8 1.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Band_3_cyto PF07565.8 CCH59513.1 - 0.28 10.6 3.5 0.15 11.5 0.6 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PIG-H PF10181.4 CCH59514.1 - 2.6e-21 75.0 0.6 4.5e-21 74.2 0.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component YukC PF10140.4 CCH59514.1 - 0.14 10.6 1.2 0.18 10.3 0.8 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PhrC_PhrF PF11131.3 CCH59514.1 - 0.18 11.3 1.5 0.33 10.5 1.0 1.4 1 0 0 1 1 1 0 Rap-phr extracellular signalling DUF2721 PF11026.3 CCH59514.1 - 0.3 10.7 3.4 0.53 9.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pkinase PF00069.20 CCH59515.1 - 6.6e-39 133.6 0.0 1.9e-38 132.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59515.1 - 1.3e-26 93.2 0.0 2.1e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59515.1 - 0.0028 16.6 0.0 0.0064 15.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like YhzD PF14120.1 CCH59515.1 - 0.11 12.4 1.6 5 7.0 0.2 2.7 2 0 0 2 2 2 0 YhzD-like protein APH PF01636.18 CCH59515.1 - 0.62 9.7 0.0 1.1 8.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 CCH59516.1 - 2.7e-94 315.9 0.0 3.7e-94 315.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CCH59516.1 - 1.4e-42 145.1 5.5 2e-24 86.0 0.5 2.4 2 0 0 2 2 2 2 Arb2 domain DUF2981 PF11200.3 CCH59516.1 - 0.022 13.8 5.4 0.039 13.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Nol1_Nop2_Fmu PF01189.12 CCH59517.1 - 2e-16 60.2 0.0 5.9e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CCH59517.1 - 0.059 13.3 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF1242 PF06842.7 CCH59518.1 - 6.6e-17 60.7 0.7 8.4e-17 60.3 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) ICE2 PF08426.5 CCH59519.1 - 1.1e-127 426.0 34.0 1.6e-127 425.5 23.6 1.2 1 0 0 1 1 1 1 ICE2 Zn_clus PF00172.13 CCH59520.1 - 4.5e-05 23.2 9.3 4.5e-05 23.2 6.5 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4041 PF13250.1 CCH59520.1 - 0.009 15.5 0.2 0.042 13.3 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4041) RINT1_TIP1 PF04437.8 CCH59521.1 - 8.6e-52 176.2 39.8 1.5e-51 175.4 24.3 2.3 2 0 0 2 2 2 2 RINT-1 / TIP-1 family HECT PF00632.20 CCH59522.1 - 3.7e-78 262.8 1.3 3.7e-78 262.8 0.9 2.6 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CCH59523.1 - 1.5e-13 50.8 0.0 3.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Daxx PF03344.10 CCH59523.1 - 4.6e-06 25.4 15.4 4.6e-06 25.4 10.7 2.7 3 0 0 3 3 3 1 Daxx Family Transformer PF06495.6 CCH59523.1 - 0.34 10.7 21.3 0.05 13.4 7.4 2.4 2 0 0 2 2 2 0 Fruit fly transformer protein Zn_clus PF00172.13 CCH59524.1 - 3.2e-08 33.3 7.3 6.6e-08 32.3 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox PF00046.24 CCH59526.1 - 1.8e-17 62.6 2.9 1.8e-17 62.6 2.0 2.0 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 CCH59526.1 - 0.014 15.0 0.3 0.05 13.3 0.2 2.0 1 0 0 1 1 1 0 Homeobox KN domain PX PF00787.19 CCH59527.1 - 4.9e-19 68.1 2.3 2.1e-18 66.1 0.0 3.1 3 1 0 3 3 3 1 PX domain Chorismate_synt PF01264.16 CCH59528.1 - 8.6e-133 442.1 0.0 9.8e-133 441.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SNF2_N PF00176.18 CCH59529.1 - 4.2e-71 239.1 4.1 4.2e-71 239.1 2.8 2.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.1 CCH59529.1 - 3.3e-51 173.0 24.4 3.3e-51 173.0 16.9 3.4 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 CCH59529.1 - 3.1e-13 49.3 0.0 1.1e-12 47.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ACPS PF01648.15 CCH59530.1 - 5.9e-11 42.2 0.0 1.4e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Mito_carr PF00153.22 CCH59531.1 - 2e-52 174.8 2.9 1.1e-19 69.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.11 CCH59532.1 - 2.6e-33 114.0 0.0 3.8e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain BESS PF02944.15 CCH59532.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 BESS motif UCH PF00443.24 CCH59533.1 - 5.6e-13 48.6 12.7 5.9e-11 41.9 8.8 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RRM_1 PF00076.17 CCH59534.1 - 1.7e-53 178.1 0.2 5.7e-18 64.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59534.1 - 5e-32 109.6 0.1 4.9e-11 42.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59534.1 - 8.9e-26 89.5 1.1 2.3e-08 33.7 0.4 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3421 PF11901.3 CCH59534.1 - 0.058 13.1 0.1 0.91 9.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3421) Sds3 PF08598.6 CCH59535.1 - 2.8e-47 160.9 26.7 1.2e-45 155.6 18.5 2.7 1 1 0 1 1 1 1 Sds3-like DUF484 PF04340.7 CCH59535.1 - 0.0024 17.3 0.8 0.0041 16.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF484 DUF2416 PF10315.4 CCH59536.1 - 1.1e-30 106.0 1.2 1.4e-30 105.7 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Toxin_61 PF15538.1 CCH59536.1 - 0.012 15.6 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Putative toxin 61 Y_phosphatase2 PF03162.8 CCH59537.1 - 1.4e-57 193.6 0.0 2.9e-57 192.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCH59537.1 - 1.9e-06 28.2 0.0 4.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CCH59537.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 CCH59537.1 - 0.035 13.6 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Aa_trans PF01490.13 CCH59538.1 - 2.3e-97 326.0 34.9 2.8e-97 325.8 24.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-BED PF02892.10 CCH59539.1 - 0.034 13.9 2.0 0.15 11.8 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger DUF2890 PF11081.3 CCH59539.1 - 0.62 10.0 11.0 1.3 9.0 7.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sigma70_ner PF04546.8 CCH59539.1 - 1 8.9 14.1 0.84 9.2 8.5 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop14 PF04147.7 CCH59539.1 - 1.8 6.4 20.2 0.12 10.2 8.6 2.3 2 0 0 2 2 2 0 Nop14-like family DUF2457 PF10446.4 CCH59539.1 - 5.2 5.6 19.8 11 4.6 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.3 CCH59539.1 - 5.3 6.9 25.1 5 7.0 15.1 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 E7 PF00527.13 CCH59539.1 - 7.5 6.7 8.6 10 6.3 0.1 2.9 2 0 0 2 2 2 0 E7 protein, Early protein DUF3719 PF12516.3 CCH59540.1 - 0.055 13.0 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) SEFIR PF08357.6 CCH59540.1 - 0.098 12.7 0.3 9.6 6.2 0.1 2.2 1 1 1 2 2 2 0 SEFIR domain Nse4_C PF08743.5 CCH59541.1 - 8.5e-25 86.6 4.3 3.4e-24 84.6 0.3 2.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CCH59541.1 - 5.3e-10 38.9 0.1 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Peptidase_M22 PF00814.20 CCH59542.1 - 1.6e-67 227.8 0.0 2e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF1620 PF07774.8 CCH59542.1 - 0.02 14.1 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1620) BcrAD_BadFG PF01869.15 CCH59542.1 - 0.039 13.2 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family CmcH_NodU PF02543.10 CCH59542.1 - 0.067 12.3 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase Mito_carr PF00153.22 CCH59543.1 - 7.1e-60 198.7 0.3 1.2e-20 72.9 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.8 CCH59544.1 - 7.5e-70 233.5 0.0 2.2e-55 186.5 0.0 2.5 1 1 1 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CCH59544.1 - 1.4e-41 140.5 0.0 4.1e-41 139.1 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region LisH PF08513.6 CCH59545.1 - 3.5e-05 23.3 1.7 7.9e-05 22.2 1.2 1.6 1 0 0 1 1 1 1 LisH eIF3_subunit PF08597.5 CCH59545.1 - 0.006 16.1 0.1 0.006 16.1 0.1 8.7 3 3 4 7 7 7 1 Translation initiation factor eIF3 subunit Bactofilin PF04519.8 CCH59545.1 - 0.19 11.7 6.0 0.68 9.9 0.2 2.8 1 1 0 2 2 2 0 Polymer-forming cytoskeletal PIR PF00399.14 CCH59546.1 - 4.9e-36 120.8 77.9 3.4e-07 29.3 2.2 8.7 8 0 0 8 8 8 8 Yeast PIR protein repeat UDPGP PF01704.13 CCH59548.1 - 1.4e-49 168.7 0.1 3.2e-49 167.5 0.0 1.6 1 1 1 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CCH59548.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain E1-E2_ATPase PF00122.15 CCH59549.1 - 2.2e-05 23.5 0.3 6.1e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Sarcoglycan_2 PF05510.8 CCH59549.1 - 0.023 13.0 0.1 0.032 12.5 0.1 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon FA_desaturase PF00487.19 CCH59549.1 - 0.27 10.6 2.7 0.86 8.9 0.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase DUF454 PF04304.8 CCH59549.1 - 2.2 8.3 7.6 0.48 10.4 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DNA_pol_B PF00136.16 CCH59550.1 - 5.4e-138 460.6 0.4 7.6e-138 460.1 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCH59550.1 - 1.8e-85 286.7 3.1 1.8e-85 286.7 2.1 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCH59550.1 - 4.4e-22 77.8 7.8 9.1e-22 76.8 5.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 CCH59550.1 - 0.024 14.1 0.1 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCH59550.1 - 0.036 13.8 1.2 0.16 11.7 0.8 2.0 1 1 0 1 1 1 0 RNase_H superfamily zinc_ribbon_2 PF13240.1 CCH59550.1 - 0.31 10.5 5.3 1 8.9 3.6 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.20 CCH59551.1 - 1.7e-72 243.7 0.0 2.4e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59551.1 - 2.5e-36 125.0 0.0 4.1e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCH59551.1 - 3.9e-15 55.7 1.1 7.2e-15 54.8 0.4 1.8 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 CCH59551.1 - 0.036 13.0 0.9 5.2 5.9 0.0 3.1 2 1 0 3 3 3 0 Kinase-like Kdo PF06293.9 CCH59551.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATG16 PF08614.6 CCH59553.1 - 2.4e-18 66.6 18.8 6.4e-17 62.0 10.2 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 CCH59553.1 - 8.3e-05 22.3 4.7 0.00011 21.8 3.3 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF724 PF05266.9 CCH59553.1 - 0.01 15.4 3.9 0.012 15.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Nup54 PF13874.1 CCH59553.1 - 0.02 14.5 2.5 0.02 14.5 1.7 1.8 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 FRQ PF09421.5 CCH59553.1 - 0.036 11.8 0.2 0.037 11.7 0.2 1.0 1 0 0 1 1 1 0 Frequency clock protein DUF641 PF04859.7 CCH59553.1 - 0.049 13.3 2.1 0.08 12.6 1.5 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pox_G5 PF04599.7 CCH59553.1 - 0.087 11.4 7.0 0.1 11.2 4.9 1.0 1 0 0 1 1 1 0 Poxvirus G5 protein H-kinase_dim PF02895.9 CCH59553.1 - 0.13 12.6 2.8 0.096 13.0 0.8 1.7 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Macoilin PF09726.4 CCH59553.1 - 0.18 10.0 5.4 0.2 9.9 3.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Corona_S2 PF01601.11 CCH59553.1 - 0.36 8.8 4.6 0.37 8.8 3.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein V_ATPase_I PF01496.14 CCH59553.1 - 0.41 8.4 5.4 0.44 8.3 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rsbr_N PF08678.5 CCH59553.1 - 0.93 9.3 7.5 2.7 7.8 2.0 2.2 1 1 1 2 2 2 0 Rsbr N terminal Atg14 PF10186.4 CCH59553.1 - 6.5 5.5 7.5 11 4.8 5.2 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 CCH59553.1 - 9.3 6.1 13.1 2.2 8.1 1.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ApoO PF09769.4 CCH59555.1 - 1.4e-33 115.8 0.0 1.8e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein O FAD_binding_6 PF00970.19 CCH59556.1 - 1.5e-11 44.2 0.0 8.8e-11 41.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CCH59556.1 - 5.3e-09 36.4 0.0 1.3e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 CCH59556.1 - 8.7e-08 32.7 0.0 1.9e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 CCH59556.1 - 0.032 13.8 0.2 0.1 12.2 0.2 1.9 1 1 0 1 1 1 0 Protoglobin NAD_binding_6 PF08030.7 CCH59556.1 - 0.04 13.8 0.1 0.41 10.5 0.1 2.3 1 1 1 2 2 2 0 Ferric reductase NAD binding domain PTCB-BRCT PF12738.2 CCH59557.1 - 9.6e-15 54.1 0.9 3.4e-09 36.4 0.0 3.7 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.21 CCH59557.1 - 5.7e-13 48.8 14.6 7.7e-06 25.9 0.2 5.4 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.2 CCH59558.1 - 6.7e-29 100.0 0.3 9.9e-09 35.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCH59558.1 - 8e-27 91.6 0.1 5.8e-06 25.8 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CCH59558.1 - 5e-26 90.5 0.2 7.3e-07 29.5 0.1 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH59558.1 - 5.7e-24 81.7 1.0 0.00038 20.4 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CCH59558.1 - 2e-21 75.4 0.0 2e-07 31.0 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DIE2_ALG10 PF04922.7 CCH59559.1 - 2e-113 379.3 33.1 2.6e-113 378.8 22.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family DUF373 PF04123.8 CCH59559.1 - 2.4 7.1 7.5 4 6.3 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Pex24p PF06398.6 CCH59560.1 - 6.3e-56 189.7 10.0 8.7e-56 189.2 6.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin 2TM PF13239.1 CCH59560.1 - 0.0075 16.3 4.2 0.018 15.0 2.5 2.0 2 0 0 2 2 2 1 2TM domain DUF639 PF04842.7 CCH59560.1 - 0.011 13.9 5.2 0.026 12.7 0.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) WD40 PF00400.27 CCH59561.1 - 2e-09 36.9 10.1 0.00021 21.0 0.1 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat BING4CT PF08149.6 CCH59561.1 - 0.011 15.1 0.0 0.63 9.5 0.0 3.2 3 0 0 3 3 3 0 BING4CT (NUC141) domain BBS2_Mid PF14783.1 CCH59561.1 - 0.028 14.1 0.0 3.3 7.5 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 CCH59562.1 - 1.8e-05 24.4 0.1 0.055 13.3 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Lactonase PF10282.4 CCH59562.1 - 0.013 14.5 0.5 0.053 12.6 0.0 2.0 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SKG6 PF08693.5 CCH59564.1 - 5.6e-11 41.5 5.5 9.1e-11 40.9 3.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 CCH59564.1 - 0.0066 16.1 0.1 0.0066 16.1 0.0 2.9 3 0 0 3 3 3 1 TMEM154 protein family Adeno_E3_CR2 PF02439.10 CCH59564.1 - 0.025 14.1 3.1 0.042 13.3 2.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Cytomega_TRL10 PF06084.6 CCH59564.1 - 0.048 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF485 PF04341.7 CCH59564.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 IncA PF04156.9 CCH59564.1 - 0.91 9.0 3.9 2.6 7.5 0.0 2.7 3 0 0 3 3 3 0 IncA protein Ribosomal_L6 PF00347.18 CCH59565.1 - 2e-29 101.8 2.6 1.7e-15 57.2 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.17 CCH59566.1 - 6.4e-42 143.7 2.3 9.3e-42 143.2 1.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 CRM1_C PF08767.6 CCH59567.1 - 2e-125 417.9 2.4 2e-125 417.9 1.7 3.0 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 CCH59567.1 - 2.2e-37 128.2 6.7 2.2e-37 128.2 4.6 4.2 4 2 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CCH59567.1 - 5.2e-13 48.7 3.1 7.4e-13 48.2 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain UCH PF00443.24 CCH59567.1 - 4.5 6.2 12.3 1.5 7.8 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Ferric_reduct PF01794.14 CCH59568.1 - 3.5e-17 62.6 13.4 3.5e-17 62.6 9.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCH59568.1 - 0.0019 18.0 0.2 0.0049 16.7 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain MMR_HSR1_C PF08438.5 CCH59569.1 - 5.2e-33 113.5 0.1 1.8e-32 111.8 0.0 1.8 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CCH59569.1 - 3.6e-18 65.6 0.0 9.5e-18 64.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH59569.1 - 5.3e-07 29.0 0.2 1.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCH59569.1 - 0.00069 19.0 0.1 0.64 9.4 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 CCH59569.1 - 0.003 17.0 0.0 0.09 12.2 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 CCH59569.1 - 0.006 16.4 1.1 0.079 12.7 0.0 2.8 3 1 1 4 4 4 1 Dynamin family ATP_bind_1 PF03029.12 CCH59569.1 - 0.012 15.1 0.7 2.6 7.5 0.1 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCH59569.1 - 0.021 15.6 0.7 0.66 10.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 CCH59569.1 - 0.029 13.1 0.8 0.24 10.1 0.0 2.5 2 1 1 3 3 3 0 ArgK protein FtsK_SpoIIIE PF01580.13 CCH59569.1 - 0.068 12.6 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 CCH59569.1 - 0.074 12.2 0.1 0.22 10.7 0.0 1.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 CCH59569.1 - 0.08 13.2 0.0 0.67 10.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 CCH59569.1 - 0.14 11.7 0.1 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain RHD3 PF05879.7 CCH59569.1 - 0.15 9.9 2.0 0.47 8.3 0.2 2.0 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) TPP_enzyme_M PF00205.17 CCH59570.1 - 1.6e-35 121.8 0.0 9.3e-35 119.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCH59570.1 - 9.5e-33 113.0 0.1 1.4e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCH59570.1 - 1.9e-12 47.0 0.0 3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 CCH59570.1 - 0.091 11.4 0.2 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 Dehydrogenase E1 component Thioredoxin PF00085.15 CCH59572.1 - 7.2e-29 99.5 0.1 8.1e-29 99.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCH59572.1 - 1.9e-08 34.4 0.3 1e-06 28.8 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCH59572.1 - 6.4e-07 29.4 0.1 1.3e-06 28.4 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 CCH59572.1 - 2.2e-06 27.2 0.1 8.2e-06 25.4 0.1 1.7 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.11 CCH59572.1 - 6.4e-06 25.7 0.0 7.3e-06 25.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_9 PF14595.1 CCH59572.1 - 1.5e-05 24.5 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CCH59572.1 - 0.00033 20.3 0.0 0.00038 20.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 CCH59572.1 - 0.0075 16.2 0.1 0.014 15.3 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CCH59572.1 - 0.047 13.1 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Phosducin PF02114.11 CCH59572.1 - 0.065 11.9 0.0 0.068 11.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin DUF2847 PF11009.3 CCH59572.1 - 0.13 11.8 0.0 0.71 9.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2847) HAD PF12710.2 CCH59573.1 - 8e-13 48.9 0.2 1.1e-12 48.4 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH59573.1 - 2.1e-11 44.6 0.6 1.3e-09 38.8 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCH59573.1 - 4.3e-07 29.7 8.6 1.4e-06 28.0 0.1 3.3 1 1 2 3 3 3 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCH59573.1 - 0.0005 19.3 0.7 0.0015 17.7 0.5 1.7 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 CCH59573.1 - 0.0027 17.9 0.0 0.049 13.8 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 CCH59573.1 - 0.22 11.1 2.4 1 8.9 0.1 2.7 1 1 1 2 2 2 0 Acid Phosphatase Ribosomal_L7Ae PF01248.21 CCH59573.1 - 0.23 10.9 2.9 7.6 6.1 0.3 3.0 2 1 1 3 3 3 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mvb12 PF09452.5 CCH59574.1 - 2.7e-20 72.3 0.3 1e-19 70.4 0.2 1.7 1 1 0 1 1 1 1 ESCRT-I subunit Mvb12 UPF0203 PF05254.7 CCH59574.1 - 0.12 12.1 2.1 0.3 10.9 1.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Aldolase_II PF00596.16 CCH59575.1 - 2e-40 138.3 0.0 2.4e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Mer2 PF09074.5 CCH59576.1 - 8.1e-18 65.0 14.3 8.1e-18 65.0 9.9 1.7 1 1 0 1 1 1 1 Mer2 Tropomyosin_1 PF12718.2 CCH59576.1 - 0.0058 16.4 8.3 0.0058 16.4 5.7 2.1 2 0 0 2 2 2 1 Tropomyosin like DUF869 PF05911.6 CCH59576.1 - 0.018 13.3 18.5 0.041 12.1 12.8 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF972 PF06156.8 CCH59576.1 - 0.099 12.9 10.9 0.12 12.7 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Lectin_N PF03954.9 CCH59576.1 - 0.12 11.7 5.9 0.51 9.7 0.9 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.14 CCH59576.1 - 2 6.1 11.7 2.6 5.8 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 CCH59576.1 - 4 7.3 17.8 0.74 9.6 8.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FTHFS PF01268.14 CCH59577.1 - 4.8e-250 830.3 1.7 6.1e-250 829.9 1.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCH59577.1 - 3.5e-54 182.2 0.6 3.5e-54 182.2 0.4 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCH59577.1 - 2.6e-36 124.1 2.3 6.1e-36 122.9 1.6 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Rhodanese PF00581.15 CCH59578.1 - 8.1e-14 51.9 0.0 1.1e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rotamase PF00639.16 CCH59579.1 - 9.4e-26 90.3 0.3 1.7e-25 89.5 0.2 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCH59579.1 - 2.4e-19 69.7 0.1 3.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CCH59579.1 - 4.3e-08 32.8 1.3 8.4e-08 31.9 0.9 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 CCH59579.1 - 1.4e-07 32.1 0.0 3.4e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain MAS20 PF02064.10 CCH59579.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor DUF4660 PF15559.1 CCH59579.1 - 0.081 13.0 3.5 0.12 12.4 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4660) CTP_transf_2 PF01467.21 CCH59580.1 - 7.4e-25 87.8 0.3 2.2e-24 86.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase DUF4611 PF15387.1 CCH59580.1 - 0.021 14.9 1.7 0.021 14.9 1.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4611) IncA PF04156.9 CCH59580.1 - 0.19 11.3 0.2 0.35 10.4 0.1 1.5 1 0 0 1 1 1 0 IncA protein PMT PF02366.13 CCH59581.1 - 1.5e-78 263.5 24.8 1.5e-78 263.5 17.2 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCH59581.1 - 5e-17 62.0 0.0 1.1e-16 60.9 0.1 1.5 2 0 0 2 2 2 1 MIR domain DUF3533 PF12051.3 CCH59582.1 - 6.6e-119 397.0 18.6 1e-118 396.4 12.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) MFS_1 PF07690.11 CCH59584.1 - 7.6e-24 84.0 40.1 1.5e-23 83.0 27.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans PF05007.8 CCH59585.1 - 2e-78 263.6 29.7 2e-78 263.6 20.6 2.2 2 1 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CCH59585.1 - 1.4e-06 27.4 34.1 4.2e-06 25.8 23.7 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 CCH59585.1 - 1.1e-05 25.0 2.8 1.1e-05 25.0 2.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) SPC12 PF06645.8 CCH59586.1 - 8.6e-23 79.9 0.2 1e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3278 PF11683.3 CCH59586.1 - 0.031 14.2 0.1 0.038 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) ZYG-11_interact PF05884.7 CCH59586.1 - 0.064 12.3 0.3 0.075 12.0 0.2 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Biotin_lipoyl PF00364.17 CCH59587.1 - 2.1e-20 72.1 0.9 4.4e-20 71.1 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCH59587.1 - 0.0011 18.5 0.0 0.003 17.1 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CCH59587.1 - 0.0089 15.6 0.5 0.63 9.7 0.0 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like ATP-sulfurylase PF01747.12 CCH59588.1 - 5.5e-88 293.8 0.1 7.2e-88 293.4 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CCH59588.1 - 1.9e-44 150.8 0.0 3.3e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Gp_dh_C PF02800.15 CCH59589.1 - 1.5e-74 248.6 0.0 2.4e-74 247.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCH59589.1 - 6.9e-58 194.8 0.2 1.3e-57 194.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CCH59589.1 - 0.012 15.5 1.2 0.021 14.7 0.2 2.1 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF2436 PF10365.4 CCH59589.1 - 0.068 12.8 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2436) Memo PF01875.12 CCH59590.1 - 3.2e-93 311.5 0.1 3.7e-93 311.3 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein Phytochelatin PF05023.9 CCH59590.1 - 0.041 12.8 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Phytochelatin synthase EIF_2_alpha PF07541.7 CCH59591.1 - 1.3e-40 137.6 0.8 1.9e-40 137.1 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCH59591.1 - 1.9e-14 53.4 1.2 4.2e-14 52.3 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CCH59591.1 - 0.056 13.3 0.4 0.14 12.1 0.2 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 RcsC PF09456.5 CCH59591.1 - 0.091 12.4 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) AA_permease PF00324.16 CCH59592.1 - 7.5e-134 446.6 34.7 9.4e-134 446.3 24.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH59592.1 - 2e-36 125.5 35.8 2.4e-36 125.1 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease NAP PF00956.13 CCH59593.1 - 1.7e-81 272.9 10.4 2.9e-81 272.1 7.2 1.4 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) MH2 PF03166.9 CCH59593.1 - 0.023 14.5 0.1 5.2 6.8 0.0 2.2 2 0 0 2 2 2 0 MH2 domain PRANC PF09372.5 CCH59593.1 - 0.22 11.5 0.1 0.22 11.5 0.0 2.2 3 0 0 3 3 3 0 PRANC domain Ribul_P_3_epim PF00834.14 CCH59594.1 - 2.6e-69 232.3 0.0 3.3e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CCH59594.1 - 0.027 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 CCH59594.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1687 PF07955.6 CCH59595.1 - 1.1e-22 80.4 1.6 1.3e-22 80.2 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DUF1073 PF06381.6 CCH59595.1 - 0.072 11.5 0.0 0.093 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) zf-H2C2 PF09337.5 CCH59596.1 - 7.4e-20 70.0 0.9 7.4e-20 70.0 0.6 1.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 CCH59596.1 - 1.2e-05 25.1 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 CCH59596.1 - 0.0034 17.5 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CedA PF10729.4 CCH59596.1 - 0.093 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Cell division activator CedA Acetyltransf_CG PF14542.1 CCH59596.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2755 PF10954.3 CCH59597.1 - 0.099 12.3 0.1 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) TrkH PF02386.11 CCH59598.1 - 1.1e-134 448.4 0.6 5.5e-132 439.6 0.0 2.3 2 1 0 2 2 2 2 Cation transport protein DUF1510 PF07423.6 CCH59598.1 - 0.0029 16.9 12.4 0.0029 16.9 8.6 4.7 4 1 0 5 5 5 1 Protein of unknown function (DUF1510) CPSase_L_D2 PF02786.12 CCH59599.1 - 1.3e-112 374.2 0.7 1.9e-84 282.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CCH59599.1 - 6.9e-47 158.2 0.0 1.6e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CCH59599.1 - 7.8e-45 152.6 0.0 1.6e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CCH59599.1 - 9.3e-43 145.2 0.0 1.9e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CCH59599.1 - 8e-41 138.5 0.1 3.4e-20 72.2 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CCH59599.1 - 5.6e-40 135.9 0.2 1.9e-39 134.2 0.2 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 CCH59599.1 - 1.7e-36 125.5 0.7 6.3e-36 123.6 0.3 2.3 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CCH59599.1 - 9.5e-33 113.4 0.2 4.6e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCH59599.1 - 7e-23 80.8 0.1 5.4e-12 45.0 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CCH59599.1 - 5.6e-19 67.8 0.0 5.4e-18 64.7 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain ATP-grasp PF02222.17 CCH59599.1 - 5.5e-15 55.1 0.4 2.1e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCH59599.1 - 1.4e-14 53.9 2.1 1.4e-07 31.1 0.2 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 CCH59599.1 - 2.2e-06 27.2 0.1 3.9e-05 23.1 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CCH59599.1 - 9.4e-05 22.3 1.1 0.47 10.3 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 CCH59599.1 - 0.002 17.6 0.0 0.006 16.0 0.0 1.8 1 0 0 1 1 1 1 DJ-1/PfpI family mIF3 PF14877.1 CCH59600.1 - 9e-45 152.2 13.0 9e-45 152.2 9.0 2.2 2 0 0 2 2 2 1 Mitochondrial translation initiation factor Solute_trans_a PF03619.11 CCH59601.1 - 5.5e-80 268.6 22.9 6.7e-80 268.3 15.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Tmemb_18A PF09771.4 CCH59601.1 - 6.7 6.7 12.2 0.94 9.4 1.1 2.4 2 0 0 2 2 2 0 Transmembrane protein 188 Mito_carr PF00153.22 CCH59602.1 - 2.6e-64 212.9 2.0 5.1e-23 80.5 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein XPG_N PF00752.12 CCH59603.1 - 3.1e-35 120.4 0.1 1.1e-34 118.7 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCH59603.1 - 1e-23 83.1 0.0 5.3e-23 80.8 0.0 2.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCH59603.1 - 0.0081 16.3 0.0 0.0081 16.3 0.0 3.9 4 0 0 4 4 4 1 5'-3' exonuclease, C-terminal SAM fold Mito_carr PF00153.22 CCH59605.1 - 1.8e-61 203.8 1.7 6.7e-21 73.8 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Ctr PF04145.10 CCH59606.1 - 3.6e-22 78.9 10.4 2.1e-21 76.4 7.2 1.8 1 1 0 1 1 1 1 Ctr copper transporter family DUF454 PF04304.8 CCH59606.1 - 0.049 13.6 0.1 0.049 13.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF1286 PF06939.6 CCH59606.1 - 1.1 9.5 4.6 3.4 7.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) RhoGAP PF00620.22 CCH59607.1 - 1.8e-09 37.3 1.1 1.1e-08 34.8 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain Fungal_trans PF04082.13 CCH59608.1 - 4.6e-30 104.3 0.2 8.3e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH59608.1 - 5.4e-08 32.6 13.5 1e-07 31.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CCH59608.1 - 0.03 14.4 8.8 0.067 13.3 6.1 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ThiF PF00899.16 CCH59609.1 - 6e-30 103.8 0.0 1.4e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCH59609.1 - 0.0018 18.3 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CCH59609.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2702 PF10863.3 CCH59610.1 - 2.8e-44 150.3 7.7 2.8e-44 150.3 5.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2702) DUF3245 PF11595.3 CCH59610.1 - 0.04 14.1 16.4 3 8.0 8.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) Arch_flagellin PF01917.11 CCH59610.1 - 0.62 9.6 5.0 0.16 11.5 0.7 1.8 1 1 0 2 2 2 0 Archaebacterial flagellin DEAD PF00270.24 CCH59611.1 - 5e-40 136.7 0.0 2.9e-39 134.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59611.1 - 2.7e-27 94.4 0.0 6.1e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH59611.1 - 0.0018 18.1 0.0 0.0075 16.1 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCH59611.1 - 0.0099 14.6 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain THP2 PF09432.5 CCH59612.1 - 4e-42 143.1 7.1 4e-42 143.1 4.9 1.8 2 1 0 2 2 2 1 Tho complex subunit THP2 ATP-synt_E_2 PF08112.6 CCH59612.1 - 0.0037 17.2 1.0 0.0037 17.2 0.7 3.5 4 2 0 4 4 4 1 ATP synthase epsilon subunit Mistic PF11458.3 CCH59612.1 - 0.058 13.8 9.8 0.083 13.3 0.9 2.6 2 1 0 2 2 2 0 Membrane-integrating protein Mistic AAA_13 PF13166.1 CCH59612.1 - 0.096 11.1 13.3 0.11 10.9 9.2 1.2 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.8 CCH59612.1 - 0.47 10.8 2.0 4.9 7.6 0.1 3.0 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF87 PF01935.12 CCH59612.1 - 0.64 9.7 9.9 0.24 11.1 1.4 2.2 1 1 0 2 2 2 0 Domain of unknown function DUF87 Rsd_AlgQ PF04353.8 CCH59612.1 - 1 9.0 7.2 0.21 11.3 1.7 2.3 2 1 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF2120 PF09893.4 CCH59612.1 - 1.1 9.1 4.9 2.4 8.1 2.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Peptidase_C65 PF10275.4 CCH59612.1 - 1.6 7.9 7.0 0.93 8.7 1.5 2.6 1 1 0 1 1 1 0 Peptidase C65 Otubain DUF342 PF03961.8 CCH59612.1 - 4 5.7 15.2 0.023 13.1 1.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF4168 PF13767.1 CCH59612.1 - 4.2 8.0 8.6 3.7 8.2 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4168) APC8 PF04049.8 CCH59613.1 - 3.2e-37 127.4 4.1 1.2e-36 125.5 2.8 1.9 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 CCH59613.1 - 1.8e-24 84.2 15.4 1.9e-05 24.0 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 CCH59613.1 - 4.9e-19 67.7 16.3 7.7e-10 38.2 0.3 5.7 6 1 1 7 7 5 3 TPR repeat TPR_2 PF07719.12 CCH59613.1 - 9.6e-19 65.7 16.0 0.00054 19.6 0.0 8.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCH59613.1 - 1.7e-16 58.7 23.8 0.00042 19.8 0.0 9.0 7 1 2 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCH59613.1 - 3.9e-13 48.7 0.0 0.0068 16.9 0.0 5.8 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCH59613.1 - 1.5e-11 44.0 15.9 0.00027 20.8 0.0 6.1 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59613.1 - 9e-11 42.1 1.4 2.5e-05 24.8 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH59613.1 - 2.1e-10 39.9 8.3 0.0012 18.8 0.0 6.7 7 1 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCH59613.1 - 2.9e-09 36.0 2.4 0.16 11.8 0.1 5.2 6 0 0 6 6 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CCH59613.1 - 2.8e-07 30.5 16.4 0.085 12.9 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 CCH59613.1 - 5.6e-07 28.6 0.2 8.2e-05 21.5 0.0 2.3 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CCH59613.1 - 5.6e-05 23.4 2.3 2.5 8.5 0.2 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat MIT PF04212.13 CCH59613.1 - 0.00012 21.9 2.0 2.1 8.2 0.0 4.2 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CCH59613.1 - 0.00014 22.1 7.4 19 5.9 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 CCH59613.1 - 0.0031 16.6 3.3 1.6 7.7 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCH59613.1 - 0.011 15.5 0.1 5 7.0 0.0 2.6 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCH59613.1 - 0.12 12.3 0.0 16 5.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat PROCN PF08083.6 CCH59614.1 - 8e-217 719.5 14.0 1.4e-216 718.6 9.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CCH59614.1 - 1.1e-118 394.6 1.2 2.5e-118 393.4 0.9 1.7 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CCH59614.1 - 5.6e-88 292.3 0.6 1.3e-87 291.1 0.4 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CCH59614.1 - 2.5e-75 251.2 6.0 2.5e-75 251.2 3.2 1.8 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CCH59614.1 - 3.3e-65 217.8 0.1 8.1e-65 216.5 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 CCH59614.1 - 6.9e-43 144.4 1.0 2.1e-42 142.8 0.7 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 CCH59614.1 - 2.6e-41 140.2 0.0 6.8e-41 138.8 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 CCH59614.1 - 0.0017 18.0 0.3 0.0055 16.4 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dna2 PF08696.6 CCH59616.1 - 6.5e-59 198.7 1.1 1.9e-58 197.2 0.8 1.9 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 CCH59616.1 - 7.8e-47 159.2 0.9 2.4e-46 157.6 0.6 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCH59616.1 - 2.8e-37 128.5 17.1 2.1e-20 73.3 0.0 5.2 4 2 1 5 5 4 2 AAA domain AAA_30 PF13604.1 CCH59616.1 - 1.5e-12 47.5 0.0 5.8e-12 45.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH59616.1 - 1.6e-08 34.1 0.1 3e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 CCH59616.1 - 3.8e-08 33.0 0.0 6.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 CCH59616.1 - 2e-05 24.2 0.0 0.79 9.1 0.0 3.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CCH59616.1 - 0.00013 21.7 0.0 0.00046 19.8 0.0 2.0 1 0 0 1 1 1 1 Helicase CbiA PF01656.18 CCH59616.1 - 0.0011 18.4 0.1 0.006 16.0 0.0 2.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 CCH59616.1 - 0.012 15.3 0.1 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCH59616.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 CCH59616.1 - 0.014 14.8 0.2 0.04 13.3 0.1 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.1 CCH59616.1 - 0.023 14.2 0.1 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cas_Cas4 PF01930.12 CCH59616.1 - 0.032 14.1 1.7 0.12 12.3 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF83 AAA_22 PF13401.1 CCH59616.1 - 0.041 14.0 0.3 1.2 9.2 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCH59616.1 - 0.1 11.9 0.0 0.77 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 CCH59616.1 - 0.11 12.7 0.0 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.1 CCH59616.1 - 1.1 9.5 7.9 2.4 8.4 0.0 4.3 5 0 0 5 5 4 0 AAA domain RRM_1 PF00076.17 CCH59617.1 - 1.4e-34 117.5 0.3 1.4e-15 56.6 0.0 5.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59617.1 - 1.4e-25 89.0 0.6 9.3e-12 44.7 0.0 5.5 3 1 1 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59617.1 - 7.6e-13 48.1 0.1 0.00072 19.3 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 CCH59617.1 - 0.034 13.4 0.0 0.27 10.5 0.0 2.4 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated CPDase PF07823.6 CCH59618.1 - 1.2e-62 210.8 0.5 1e-60 204.5 0.3 2.0 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CCH59618.1 - 0.001 18.8 0.0 0.54 9.9 0.0 2.1 2 0 0 2 2 2 2 2'-5' RNA ligase superfamily TFIIB PF00382.14 CCH59619.1 - 6.2e-49 163.6 4.9 6.7e-24 83.4 0.4 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CCH59619.1 - 1.5e-29 102.0 2.4 3.3e-29 100.9 1.6 1.6 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CCH59619.1 - 3.7e-10 38.9 2.3 6.7e-10 38.1 1.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CCH59619.1 - 0.00014 21.4 0.2 0.1 12.1 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain SbcD_C PF12320.3 CCH59619.1 - 0.061 13.3 1.0 0.17 11.8 0.7 1.8 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain SNF2_N PF00176.18 CCH59620.1 - 4.9e-68 229.1 0.4 7.1e-68 228.5 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CCH59620.1 - 2.4e-49 167.7 1.0 2.4e-49 167.7 0.7 2.5 3 0 0 3 3 3 1 Rad54 N terminal Helicase_C PF00271.26 CCH59620.1 - 2.7e-13 49.5 0.0 8.3e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCH59620.1 - 7.2e-09 34.8 0.3 7.2e-09 34.8 0.2 3.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TBP PF00352.16 CCH59621.1 - 6.5e-70 230.5 0.1 4.1e-35 118.9 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CCH59621.1 - 0.00014 21.8 0.2 0.62 10.1 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) KaiC PF06745.8 CCH59622.1 - 1.7e-07 30.5 0.1 3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_18 PF13238.1 CCH59622.1 - 0.0012 19.1 0.4 0.058 13.6 0.0 2.8 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCH59622.1 - 0.0025 17.5 1.6 0.0025 17.5 1.1 2.1 2 1 0 2 2 2 1 Archaeal ATPase Rad51 PF08423.6 CCH59622.1 - 0.0036 16.2 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA PF00004.24 CCH59622.1 - 0.0037 17.4 0.0 0.019 15.1 0.0 2.1 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RecA PF00154.16 CCH59622.1 - 0.0094 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 CCH59622.1 - 0.024 14.7 0.0 0.064 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCH59622.1 - 0.13 12.1 3.0 0.57 10.0 2.1 2.2 1 1 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 CCH59624.1 - 7.7e-17 61.2 0.0 9.9e-17 60.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCH59624.1 - 0.027 13.2 0.0 6 5.4 0.0 2.6 2 1 1 3 3 3 0 Aminotransferase class-V Aminotran_MocR PF12897.2 CCH59624.1 - 0.068 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase UPF0160 PF03690.8 CCH59625.1 - 2.5e-121 405.0 0.0 2.8e-121 404.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Cofilin_ADF PF00241.15 CCH59626.1 - 8.4e-10 38.6 0.1 1.1e-09 38.2 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein GDI PF00996.13 CCH59627.1 - 8.6e-213 706.4 0.5 9.8e-213 706.2 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCH59627.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CCH59627.1 - 0.15 11.1 0.0 2.3 7.2 0.0 2.0 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase LSM PF01423.17 CCH59628.1 - 2e-16 59.2 0.2 2.7e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCH59628.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain zf-CCHC PF00098.18 CCH59629.1 - 0.044 13.7 2.5 0.07 13.0 1.7 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF1041 PF06292.12 CCH59629.1 - 0.047 13.8 2.9 0.13 12.4 1.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) DUF1706 PF08020.6 CCH59629.1 - 0.098 12.1 1.3 0.18 11.3 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) PMC2NT PF08066.7 CCH59629.1 - 0.1 12.9 3.3 0.14 12.4 2.0 1.5 1 1 0 1 1 1 0 PMC2NT (NUC016) domain DUF4640 PF15480.1 CCH59629.1 - 0.11 12.0 6.5 0.12 11.9 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4640) YyzF PF14116.1 CCH59629.1 - 0.13 12.1 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 YyzF-like protein Paramyxo_P PF01806.12 CCH59629.1 - 0.22 10.7 6.1 0.28 10.3 4.3 1.1 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region Ycf1 PF05758.7 CCH59629.1 - 0.5 8.0 6.9 0.56 7.8 4.8 1.1 1 0 0 1 1 1 0 Ycf1 MCM PF00493.18 CCH59630.1 - 4.5e-141 469.4 0.2 7e-141 468.8 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CCH59630.1 - 3.9e-28 98.3 29.8 3.9e-28 98.3 20.7 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CCH59630.1 - 4.2e-12 46.6 0.1 1.3e-11 45.0 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCH59630.1 - 2.7e-09 36.5 0.0 2.7e-07 29.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCH59630.1 - 1.9e-07 30.8 0.0 4.2e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCH59630.1 - 0.00065 19.3 0.0 0.0031 17.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCH59630.1 - 0.0013 18.2 0.1 0.011 15.2 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CCH59630.1 - 0.021 15.0 0.0 0.063 13.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ApoO PF09769.4 CCH59630.1 - 0.16 11.6 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 Apolipoprotein O Aldedh PF00171.17 CCH59631.1 - 4.6e-39 134.0 0.0 1.1e-24 86.6 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family CBFD_NFYB_HMF PF00808.18 CCH59632.1 - 3.3e-24 84.7 0.1 4.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCH59632.1 - 3.7e-05 23.7 0.0 5.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CCH59632.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated RVT_2 PF07727.9 CCH59633.1 - 2.6e-21 75.7 0.0 4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Tubulin-binding PF00418.14 CCH59634.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Tau and MAP protein, tubulin-binding repeat gag_pre-integrs PF13976.1 CCH59635.1 - 6e-07 29.0 0.9 5.8e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 CCH59635.1 - 0.0039 16.9 0.1 0.0087 15.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C4pol PF14260.1 CCH59635.1 - 0.16 11.9 2.7 0.8 9.7 0.2 2.3 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DHBP_synthase PF00926.14 CCH59636.1 - 2.1e-77 258.7 0.0 2.4e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.27 CCH59637.1 - 0.002 17.9 0.5 0.037 13.9 0.1 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4531 PF15041.1 CCH59637.1 - 0.046 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) PQQ_3 PF13570.1 CCH59637.1 - 0.046 13.9 1.0 0.87 9.9 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain SPASM PF13186.1 CCH59637.1 - 0.19 12.1 1.1 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain Sld5 PF05916.6 CCH59638.1 - 3.1e-14 53.1 0.3 7.1e-14 52.0 0.2 1.6 1 0 0 1 1 1 1 GINS complex protein Peptidase_M16_C PF05193.16 CCH59639.1 - 2.3e-14 53.5 0.0 1e-11 44.8 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCH59639.1 - 2.2e-08 33.9 0.0 9.9e-08 31.8 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF2312 PF10073.4 CCH59639.1 - 0.007 15.7 5.3 1 8.7 1.8 2.9 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2312) DUF2833 PF11090.3 CCH59639.1 - 0.076 13.1 0.3 29 4.8 0.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2833) Pkinase PF00069.20 CCH59640.1 - 1.5e-63 214.3 0.2 4.4e-63 212.8 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59640.1 - 4.2e-33 114.5 0.0 7.3e-33 113.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59640.1 - 2e-08 33.5 0.0 5.8e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCH59640.1 - 0.00076 18.6 0.0 0.002 17.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH59640.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HlyIII PF03006.15 CCH59641.1 - 6.4e-45 153.2 9.8 7.7e-45 153.0 6.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4631 PF15450.1 CCH59642.1 - 0.057 11.7 0.3 0.061 11.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) BBP1_C PF15272.1 CCH59642.1 - 0.081 12.4 0.2 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal PTS_2-RNA PF01885.11 CCH59643.1 - 2.2e-48 164.0 0.2 3.4e-48 163.4 0.1 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family SpoU_sub_bind PF08032.7 CCH59643.1 - 0.071 13.2 0.3 1.4 9.1 0.2 2.4 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding DUF1825 PF08855.5 CCH59644.1 - 0.037 14.0 0.1 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Vps39_2 PF10367.4 CCH59645.1 - 0.017 15.3 0.7 0.52 10.5 0.1 3.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Sugar_tr PF00083.19 CCH59646.1 - 5.1e-144 480.2 32.5 6.2e-144 479.9 22.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59646.1 - 7.3e-30 103.8 34.5 5.2e-27 94.4 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH59646.1 - 0.00034 18.9 5.5 0.00034 18.9 3.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCH59646.1 - 0.0027 15.9 0.6 0.0027 15.9 0.4 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector Sec20 PF03908.8 CCH59647.1 - 3.7e-30 103.4 3.1 3.7e-30 103.4 2.2 2.3 2 1 0 2 2 2 1 Sec20 SOBP PF15279.1 CCH59647.1 - 0.5 10.7 4.9 0.74 10.1 3.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2203 PF09969.4 CCH59647.1 - 5 7.3 8.4 1.2e+02 2.9 5.8 2.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ERG4_ERG24 PF01222.12 CCH59648.1 - 6.3e-144 479.6 19.3 7.2e-144 479.5 13.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCH59648.1 - 2.7e-06 26.8 1.6 2.7e-06 26.8 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) GIDA PF01134.17 CCH59649.1 - 0.06 12.2 2.0 0.068 12.0 1.4 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NESP55 PF06390.7 CCH59649.1 - 1.1 8.5 4.9 1.5 8.0 3.4 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RVT_2 PF07727.9 CCH59650.1 - 3.4e-21 75.3 0.4 8.3e-21 74.0 0.2 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCH59650.1 - 0.0025 17.1 0.1 0.0076 15.6 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 CCH59650.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 RNase H Aha1_N PF09229.6 CCH59651.1 - 6.6e-32 110.1 0.4 7.5e-32 110.0 0.3 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.6 CCH59652.1 - 3.9e-39 134.0 0.4 4.8e-39 133.7 0.2 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 CCH59653.1 - 6.5e-11 42.0 10.6 2.2e-10 40.2 7.4 2.0 1 0 0 1 1 1 1 WSC domain Pox_A14 PF05767.7 CCH59653.1 - 0.0093 15.9 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 DUF456 PF04306.8 CCH59653.1 - 0.017 15.1 0.3 0.028 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Adeno_E3_CR2 PF02439.10 CCH59653.1 - 0.16 11.5 6.0 0.61 9.6 4.2 2.0 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GST_C PF00043.20 CCH59654.1 - 5.1e-09 35.9 0.0 7.6e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCH59654.1 - 8.4e-07 29.0 0.0 4e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCH59654.1 - 0.001 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCH59654.1 - 0.008 16.6 0.1 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1751 PF08551.5 CCH59655.1 - 1.3e-18 67.1 3.9 1.3e-18 67.1 2.7 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) ADH_zinc_N PF00107.21 CCH59656.1 - 3.7e-11 42.6 0.0 6.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH59656.1 - 9e-07 28.6 0.2 3.6e-06 26.6 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HLH PF00010.21 CCH59657.1 - 0.001 18.6 0.5 0.0047 16.5 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Adaptin_N PF01602.15 CCH59658.1 - 3.4e-112 375.4 17.0 4.4e-112 375.0 11.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CCH59658.1 - 4.1e-49 166.2 4.4 1.3e-48 164.5 3.0 2.0 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CCH59658.1 - 4e-08 33.4 1.5 0.004 17.4 0.0 4.4 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CCH59658.1 - 0.02 14.9 3.6 4.5 7.6 0.0 5.5 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 CCH59658.1 - 0.25 11.9 0.8 1.3 9.5 0.1 2.8 2 1 0 2 2 2 0 HEAT-like repeat Cyclin_N PF00134.18 CCH59659.1 - 4.8e-17 61.7 0.1 7.1e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCH59659.1 - 2.9e-09 37.4 0.0 4.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin AAA PF00004.24 CCH59660.1 - 8.8e-18 64.7 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCH59660.1 - 1.7e-17 63.5 0.8 3.2e-15 56.1 0.0 2.9 3 1 0 3 3 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CCH59660.1 - 5.2e-15 55.1 0.0 1.3e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CCH59660.1 - 2.1e-07 31.1 0.4 0.017 15.3 0.1 2.4 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 CCH59660.1 - 2.5e-07 29.7 0.4 7.6e-06 24.8 0.1 2.5 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CCH59660.1 - 8.5e-07 28.2 0.0 1.7e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCH59660.1 - 1.5e-06 28.2 0.0 4.6e-05 23.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCH59660.1 - 2.9e-06 27.2 0.0 8.1e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 CCH59660.1 - 7.3e-06 25.6 0.4 1.3e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 CCH59660.1 - 8e-06 25.5 0.4 2.1e-05 24.2 0.3 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCH59660.1 - 5.5e-05 22.2 0.0 7.5e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 CCH59660.1 - 6e-05 22.7 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CCH59660.1 - 0.00032 20.1 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCH59660.1 - 0.00056 20.7 0.0 0.001 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCH59660.1 - 0.00062 19.5 0.2 0.0044 16.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CCH59660.1 - 0.00067 18.4 0.0 0.055 12.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 CCH59660.1 - 0.0012 19.0 0.1 0.0052 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCH59660.1 - 0.0022 17.4 0.1 0.03 13.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 CCH59660.1 - 0.0023 17.7 0.1 0.081 12.7 0.0 2.5 1 1 2 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCH59660.1 - 0.0025 17.3 0.1 0.022 14.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_3 PF07726.6 CCH59660.1 - 0.0035 16.9 0.0 0.0077 15.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCH59660.1 - 0.0035 16.9 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CCH59660.1 - 0.0043 16.6 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCH59660.1 - 0.0048 16.4 0.0 0.11 12.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 CCH59660.1 - 0.0077 15.7 0.2 0.21 11.0 0.0 2.3 1 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 CCH59660.1 - 0.0088 15.5 0.3 0.7 9.2 0.2 2.4 1 1 0 1 1 1 1 AAA-like domain Mg_chelatase PF01078.16 CCH59660.1 - 0.01 15.0 0.0 0.065 12.3 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCH59660.1 - 0.014 15.3 0.1 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCH59660.1 - 0.022 15.0 2.5 0.065 13.5 1.7 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCH59660.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 CCH59660.1 - 0.024 13.6 0.1 0.073 12.0 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 CCH59660.1 - 0.027 14.1 0.0 0.074 12.7 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCH59660.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CCH59660.1 - 0.036 14.0 0.0 0.068 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 CCH59660.1 - 0.05 13.2 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein SNF2_N PF00176.18 CCH59660.1 - 0.057 12.1 0.0 0.18 10.5 0.0 1.8 1 1 0 1 1 1 0 SNF2 family N-terminal domain Mid1 PF12929.2 CCH59661.1 - 4.4e-101 338.7 16.8 9.4e-101 337.5 11.6 1.5 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Erf4 PF10256.4 CCH59662.1 - 1.1e-28 99.4 0.1 1.4e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ubiquitin PF00240.18 CCH59663.1 - 3.9e-08 32.5 1.8 5.6e-08 32.0 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CCH59663.1 - 4.9e-05 23.1 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 CCH59663.1 - 8.3e-05 22.6 0.3 0.00021 21.4 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term RabGAP-TBC PF00566.13 CCH59664.1 - 1.9e-41 141.9 6.4 1.8e-32 112.5 0.3 4.1 5 1 0 5 5 5 2 Rab-GTPase-TBC domain PalH PF08733.5 CCH59665.1 - 5.5e-69 232.6 15.8 5.5e-69 232.6 11.0 1.5 2 0 0 2 2 2 1 PalH/RIM21 Ribosomal_L32p PF01783.18 CCH59665.1 - 1.1 9.5 6.5 5.7 7.1 4.8 2.0 2 0 0 2 2 2 0 Ribosomal L32p protein family Pet20 PF08692.5 CCH59666.1 - 3.1e-09 36.9 0.3 2.3e-08 34.0 0.2 2.3 1 1 0 1 1 1 1 Mitochondrial protein Pet20 Pkinase PF00069.20 CCH59667.1 - 1.7e-65 220.7 0.1 1.7e-65 220.7 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59667.1 - 1.9e-50 171.3 0.0 1.9e-50 171.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 CCH59667.1 - 3.2e-21 75.4 0.3 3.2e-21 75.4 0.2 3.8 3 1 0 3 3 3 1 P21-Rho-binding domain PH PF00169.24 CCH59667.1 - 1.8e-09 37.7 1.3 1.8e-09 37.7 0.9 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 CCH59667.1 - 2.8e-07 29.7 0.0 6.1e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH59667.1 - 0.0016 18.2 0.1 0.0086 15.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH_11 PF15413.1 CCH59667.1 - 0.19 11.9 2.1 0.2 11.9 0.2 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain NTP_transf_2 PF01909.18 CCH59668.1 - 6.1e-14 52.1 0.1 1.4e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCH59668.1 - 1.6e-12 47.1 0.0 3.1e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase GCR1_C PF12550.3 CCH59669.1 - 4.8e-25 87.2 0.2 8.2e-25 86.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SlyX PF04102.7 CCH59669.1 - 0.25 11.7 1.4 1.6 9.1 1.0 2.4 1 1 0 1 1 1 0 SlyX LMWSLP_N PF12211.3 CCH59670.1 - 0.11 12.2 11.1 0.14 12.0 7.7 1.2 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal C6 PF01681.12 CCH59670.1 - 8.3 6.5 12.6 0.94 9.5 4.4 2.4 1 1 1 2 2 2 0 C6 domain Redoxin PF08534.5 CCH59672.1 - 1.6e-22 79.6 0.0 2e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCH59672.1 - 2.9e-10 39.8 0.0 3.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Nramp PF01566.13 CCH59673.1 - 5.9e-88 295.0 17.7 5.9e-88 295.0 12.3 2.5 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein RRM_1 PF00076.17 CCH59674.1 - 4.6e-36 122.2 2.2 4.5e-19 67.8 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59674.1 - 9.3e-32 108.8 0.2 1.4e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59674.1 - 1.8e-12 46.9 4.5 8.3e-06 25.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UPF0020 PF01170.13 CCH59675.1 - 5.8e-13 48.7 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCH59675.1 - 1.3e-06 28.3 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ras PF00071.17 CCH59676.1 - 1.9e-25 89.1 0.5 2e-20 72.8 0.1 2.7 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCH59676.1 - 2.7e-11 44.0 0.0 6.7e-06 26.5 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein TRM13 PF05206.9 CCH59677.1 - 1.9e-68 230.5 0.1 3.2e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CCH59677.1 - 1e-11 43.9 4.9 3e-11 42.4 3.4 1.9 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 CCH59677.1 - 1.5e-09 37.3 3.5 4e-09 36.0 2.4 1.8 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 CCH59677.1 - 0.00026 20.6 0.2 0.00056 19.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ldh_1_N PF00056.18 CCH59678.1 - 4.9e-36 123.6 0.3 7.4e-36 123.0 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCH59678.1 - 1.2e-33 116.2 0.0 1.9e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 CCH59678.1 - 0.0029 16.9 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase OCD_Mu_crystall PF02423.10 CCH59678.1 - 0.0078 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_Gly3P_dh_N PF01210.18 CCH59678.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.14 CCH59678.1 - 0.024 13.3 0.1 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Bax1-I PF01027.15 CCH59679.1 - 5.4e-32 111.0 27.8 8.9e-32 110.3 19.3 1.3 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Phlebovirus_G1 PF07243.6 CCH59679.1 - 0.39 8.8 2.2 0.55 8.3 1.5 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Pkinase PF00069.20 CCH59680.1 - 1.4e-54 184.9 0.0 1.8e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59680.1 - 7.4e-26 90.7 0.0 1.1e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59680.1 - 7.9e-08 31.6 0.0 1.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH59680.1 - 0.00011 21.9 0.0 0.004 16.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCH59680.1 - 0.0055 15.8 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 CCH59680.1 - 0.0062 15.2 0.2 0.11 11.1 0.2 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 CCH59680.1 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase UPF0220 PF05255.6 CCH59681.1 - 1.5e-67 226.0 0.4 1.8e-67 225.7 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Det1 PF09737.4 CCH59682.1 - 0.045 12.5 1.0 0.056 12.2 0.2 1.4 1 1 0 1 1 1 0 De-etiolated protein 1 Det1 DUF2547 PF10818.3 CCH59682.1 - 0.053 14.1 7.2 0.044 14.3 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) TPR_11 PF13414.1 CCH59683.1 - 2.5e-13 49.4 5.4 1.4e-09 37.4 0.1 5.0 3 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.1 CCH59683.1 - 1.6e-08 34.4 1.4 0.093 13.4 0.0 5.4 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCH59683.1 - 1.5e-07 30.6 0.2 0.22 11.1 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCH59683.1 - 2.1e-07 30.2 0.6 0.011 15.5 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCH59683.1 - 2.7e-06 27.6 1.2 0.043 14.1 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH59683.1 - 3.9e-06 26.6 1.5 0.0034 17.4 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCH59683.1 - 4.1e-06 26.6 0.5 0.057 13.3 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59683.1 - 6.7e-05 23.4 0.9 6.7 7.5 0.0 4.5 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCH59683.1 - 0.00052 19.6 3.7 1.4 8.8 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.4 CCH59683.1 - 0.0044 16.4 2.4 0.079 12.3 0.1 3.3 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 CCH59683.1 - 0.081 12.7 2.9 19 5.3 0.0 4.9 5 1 0 5 5 4 0 Tetratricopeptide repeat Meiotic_rec114 PF03525.9 CCH59684.1 - 8.5e-09 34.3 11.9 1.3e-08 33.7 8.2 1.4 1 1 0 1 1 1 1 Meiotic recombination protein rec114 ATP11 PF06644.6 CCH59685.1 - 9.1e-84 281.0 1.9 1.1e-83 280.8 1.3 1.0 1 0 0 1 1 1 1 ATP11 protein zf-rbx1 PF12678.2 CCH59686.1 - 8.8e-32 109.0 13.9 1.1e-31 108.6 9.7 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCH59686.1 - 1.6e-16 59.8 10.6 2.3e-16 59.4 7.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CCH59686.1 - 1.3e-06 28.1 12.6 9.1e-06 25.4 8.7 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCH59686.1 - 0.0003 20.3 12.4 0.0017 17.9 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH59686.1 - 0.014 15.4 2.7 0.014 15.4 1.9 2.4 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CCH59686.1 - 0.036 13.5 3.3 0.059 12.8 2.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 CCH59686.1 - 0.038 13.6 10.0 1.5 8.5 7.0 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCH59686.1 - 0.18 11.7 9.1 0.89 9.5 6.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 CCH59686.1 - 0.69 9.6 11.5 4.9 6.9 8.0 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCH59686.1 - 1.4 8.8 9.6 0.23 11.3 0.4 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCH59686.1 - 2.7 7.7 7.8 7.2 6.4 4.3 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 CCH59686.1 - 2.9 8.1 10.0 1.4e+02 2.7 6.8 2.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain Med7 PF05983.6 CCH59687.1 - 9.1e-67 223.8 6.8 1.1e-66 223.6 4.7 1.1 1 0 0 1 1 1 1 MED7 protein PapD_N PF00345.15 CCH59687.1 - 0.056 13.2 1.1 0.22 11.2 0.3 2.0 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain PA28_alpha PF02251.13 CCH59687.1 - 2.8 8.1 5.7 16 5.7 0.1 3.3 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit Prefoldin_2 PF01920.15 CCH59687.1 - 5 6.9 12.6 0.066 12.9 1.6 2.7 3 0 0 3 3 3 0 Prefoldin subunit WD40 PF00400.27 CCH59688.1 - 3.9e-38 127.9 16.3 6.9e-10 38.4 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CCH59688.1 - 1.9e-08 34.2 3.6 3.4e-06 26.9 1.7 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CCH59688.1 - 3.8e-05 22.6 5.1 0.26 10.0 1.2 4.0 1 1 1 2 2 2 2 Nup133 N terminal like COX6B PF02297.12 CCH59689.1 - 1.2e-19 70.0 5.4 1.4e-19 69.8 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 CCH59689.1 - 0.51 9.7 3.4 1.3 8.4 2.4 1.7 1 1 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 CCH59689.1 - 0.56 10.0 4.6 2.7 7.8 0.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) RIC1 PF07064.8 CCH59690.1 - 5.2e-17 62.1 2.0 2.5e-13 50.0 0.6 2.3 2 0 0 2 2 2 2 RIC1 Atrophin-1 PF03154.10 CCH59690.1 - 1.9 6.5 4.3 2.6 6.0 3.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF814 PF05670.8 CCH59691.1 - 2.8e-16 59.1 0.0 6.5e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DUF2951 PF11166.3 CCH59691.1 - 6.5 6.6 10.4 12 5.8 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) SRP1_TIP1 PF00660.12 CCH59692.1 - 2.9e-06 27.0 1.2 5e-06 26.2 0.2 2.0 1 1 1 2 2 2 1 Seripauperin and TIP1 family POM121 PF15229.1 CCH59692.1 - 6.5 6.1 16.6 8.5 5.7 11.5 1.1 1 0 0 1 1 1 0 POM121 family CLTH PF10607.4 CCH59694.1 - 1.7e-23 82.9 2.9 1.7e-23 82.9 2.0 2.7 2 1 1 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.22 CCH59695.1 - 4.7e-16 57.8 4.5 1.3e-15 56.4 3.1 1.8 1 0 0 1 1 1 1 GATA zinc finger Stc1 PF12898.2 CCH59695.1 - 0.15 12.1 1.4 0.23 11.5 0.1 1.9 2 0 0 2 2 2 0 Stc1 domain DRMBL PF07522.9 CCH59696.1 - 3.2e-23 81.8 0.1 1.2e-22 80.0 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCH59696.1 - 4.4e-10 39.4 0.0 9.3e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.20 CCH59697.1 - 3.9e-48 163.8 0.2 4.9e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59697.1 - 5.2e-16 58.4 0.1 7.1e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CCH59697.1 - 0.0013 18.3 0.1 0.0022 17.5 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCH59697.1 - 0.0088 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family WHIM1 PF15612.1 CCH59697.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 TPP_enzyme_N PF02776.13 CCH59698.1 - 2.3e-28 98.8 0.0 3.7e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCH59698.1 - 2.3e-23 82.4 0.0 3.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCH59698.1 - 6.5e-13 48.5 0.0 1.6e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain zf-C3HC4_2 PF13923.1 CCH59699.1 - 3.4 7.7 10.4 19 5.4 7.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 CCH59700.1 - 2.1e-23 82.5 12.3 2.6e-23 82.2 8.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L13e PF01294.13 CCH59701.1 - 1.8e-67 226.3 3.0 2.4e-67 225.8 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.14 CCH59702.1 - 7.3e-39 132.7 0.3 8.3e-39 132.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DEAD PF00270.24 CCH59704.1 - 8.2e-35 119.7 0.2 2.1e-34 118.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59704.1 - 1.8e-23 82.1 0.0 3.6e-22 78.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH59704.1 - 1.7e-05 24.6 0.0 5.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1919 PF08942.5 CCH59704.1 - 0.049 12.9 0.3 0.091 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) HTH_psq PF05225.11 CCH59705.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 CCH59705.1 - 0.0056 16.4 0.0 0.022 14.5 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Pyr_redox_2 PF07992.9 CCH59706.1 - 6.6e-25 88.1 0.0 7e-15 55.4 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCH59706.1 - 3.5e-12 46.5 0.1 2e-11 44.1 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH59706.1 - 5.3e-06 26.6 0.7 0.051 13.6 0.0 3.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCH59706.1 - 0.0055 15.6 0.0 0.04 12.8 0.0 2.1 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Aldo_ket_red PF00248.16 CCH59707.1 - 1.7e-38 132.0 0.0 2e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Diphtheria_C PF02763.9 CCH59707.1 - 0.073 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain WD40 PF00400.27 CCH59708.1 - 1e-30 104.4 23.8 0.00084 19.1 0.1 10.8 10 1 0 10 10 10 7 WD domain, G-beta repeat eIF2A PF08662.6 CCH59708.1 - 1.5e-07 31.3 6.2 0.53 9.9 0.0 5.6 4 2 0 5 5 5 4 Eukaryotic translation initiation factor eIF2A Vma12 PF11712.3 CCH59710.1 - 5.2e-33 113.7 0.4 6.9e-33 113.3 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase OPT PF03169.10 CCH59710.1 - 0.015 13.7 0.0 0.017 13.5 0.0 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF3169 PF11368.3 CCH59710.1 - 0.035 13.3 3.9 0.048 12.8 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF3043 PF11241.3 CCH59710.1 - 0.17 11.4 0.2 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4234 PF14018.1 CCH59710.1 - 0.23 11.2 2.4 0.31 10.8 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) DUF3671 PF12420.3 CCH59710.1 - 4.5 7.3 14.9 0.053 13.4 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function Prenyltransf PF01255.14 CCH59711.1 - 6.3e-66 221.7 2.1 9.1e-66 221.1 1.4 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Mer2 PF09074.5 CCH59711.1 - 1.3 8.9 8.0 5.5 6.8 5.5 1.9 1 1 0 1 1 1 0 Mer2 Mito_carr PF00153.22 CCH59712.1 - 2.9e-47 158.2 9.4 1.3e-15 56.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 CCH59713.1 - 8e-20 69.9 20.9 6.1e-06 25.9 0.4 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat TF_Zn_Ribbon PF08271.7 CCH59713.1 - 0.061 12.6 1.7 0.15 11.3 1.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding SRP9-21 PF05486.7 CCH59714.1 - 3.2e-19 68.4 3.8 3.8e-19 68.1 2.6 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Capsid_NCLDV PF04451.7 CCH59714.1 - 0.035 13.1 0.9 0.039 12.9 0.6 1.1 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Man-6-P_recep PF02157.10 CCH59714.1 - 0.13 11.2 0.1 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor SPRY PF00622.23 CCH59715.1 - 4.3e-12 46.1 0.0 2.2e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 SPRY domain PGM_PMM_I PF02878.11 CCH59716.1 - 2.3e-35 121.0 0.2 3.6e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCH59716.1 - 4.5e-26 91.1 0.0 8.4e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCH59716.1 - 1.7e-12 47.6 0.0 5e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCH59716.1 - 1e-09 38.2 0.0 2.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.11 CCH59717.1 - 3.6e-31 108.1 5.3 3.6e-31 108.1 3.6 2.2 2 1 0 2 2 2 1 Ku70/Ku80 beta-barrel domain His_Phos_1 PF00300.17 CCH59718.1 - 1.2e-18 67.6 0.0 1.8e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Myosin_head PF00063.16 CCH59719.1 - 1.6e-222 740.3 7.6 2.8e-222 739.5 5.3 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCH59719.1 - 1.5e-48 164.7 2.0 5.1e-48 163.0 0.2 2.4 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 CCH59719.1 - 9.9e-13 47.2 0.1 2e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH59719.1 - 6.4e-09 35.2 0.1 1.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH59719.1 - 1.3e-06 27.8 0.0 2.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 CCH59719.1 - 0.0047 17.0 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SH3_3 PF08239.6 CCH59719.1 - 0.0098 16.0 0.2 0.024 14.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_19 PF13245.1 CCH59719.1 - 0.024 14.3 0.0 0.19 11.4 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 CCH59719.1 - 0.031 13.9 0.0 0.088 12.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CCH59719.1 - 0.037 14.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 CCH59719.1 - 0.044 14.5 0.0 0.18 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 CCH59719.1 - 0.064 12.5 0.1 4.8 6.4 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.21 CCH59719.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain She2p PF11435.3 CCH59720.1 - 1.2e-80 269.7 13.3 1.5e-80 269.4 9.2 1.0 1 0 0 1 1 1 1 RNA binding protein She2p Phage_C PF12025.3 CCH59720.1 - 0.17 11.8 1.5 0.31 11.0 0.2 2.0 2 0 0 2 2 2 0 Phage protein C GCR1_C PF12550.3 CCH59721.1 - 2.5e-17 62.5 0.5 2.5e-17 62.5 0.3 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes RasGEF_N_2 PF14663.1 CCH59721.1 - 0.059 13.3 0.1 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Med11 PF10280.4 CCH59722.1 - 1.1e-19 70.6 2.2 1.3e-19 70.3 1.6 1.1 1 0 0 1 1 1 1 Mediator complex protein BLOC1_2 PF10046.4 CCH59722.1 - 0.012 15.7 1.2 0.1 12.7 0.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RmuC PF02646.11 CCH59722.1 - 0.015 14.1 2.0 0.093 11.5 1.0 2.3 1 1 0 1 1 1 0 RmuC family Mating_N PF12731.2 CCH59722.1 - 0.019 14.8 0.2 0.074 12.9 0.1 1.9 1 1 1 2 2 2 0 Mating-type protein beta 1 ING PF12998.2 CCH59722.1 - 0.024 14.8 1.7 0.083 13.1 0.4 2.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Baculo_PEP_C PF04513.7 CCH59722.1 - 0.047 13.5 0.6 0.1 12.4 0.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CCH59722.1 - 0.064 12.7 2.4 0.11 12.0 1.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Topoisom_I_N PF02919.10 CCH59722.1 - 0.09 12.0 0.1 0.098 11.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RPW8 PF05659.6 CCH59722.1 - 0.097 12.2 0.5 0.47 9.9 0.0 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.6 CCH59722.1 - 0.14 10.7 2.7 0.23 10.0 1.9 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein SYCE1 PF15233.1 CCH59722.1 - 5.7 6.8 7.7 49 3.8 4.2 2.4 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 DUF159 PF02586.9 CCH59723.1 - 2.9e-53 180.4 4.3 2.9e-53 180.4 3.0 2.0 2 1 0 2 2 2 1 Uncharacterised ACR, COG2135 KBP_C PF12309.3 CCH59724.1 - 0.0028 16.6 8.6 0.018 14.0 0.2 3.2 2 1 1 3 3 3 2 KIF-1 binding protein C terminal MIT PF04212.13 CCH59724.1 - 0.0084 15.9 1.9 0.48 10.3 0.2 2.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 CCH59724.1 - 0.011 15.6 7.4 0.67 9.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCH59724.1 - 0.03 14.2 5.3 0.17 11.8 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCH59724.1 - 0.044 13.4 9.8 0.14 11.7 1.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCH59724.1 - 0.045 13.3 9.4 0.23 11.1 1.4 3.7 3 1 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 CCH59724.1 - 0.095 12.5 10.4 1.4 8.9 0.6 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 CCH59725.1 - 7.8e-57 187.2 13.2 5.1e-09 35.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCH59725.1 - 0.0001 22.0 0.1 0.0021 17.7 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCH59725.1 - 0.0002 19.6 5.7 0.12 10.4 0.0 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCH59725.1 - 0.0049 15.6 1.9 1.7 7.3 0.1 4.1 1 1 4 5 5 5 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCH59725.1 - 0.018 13.3 0.1 0.13 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1513 PF07433.6 CCH59725.1 - 0.019 13.8 0.2 0.41 9.4 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Adaptin_N PF01602.15 CCH59726.1 - 4.3e-128 427.9 17.7 5.7e-128 427.5 12.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCH59726.1 - 5.6e-20 71.9 12.7 9.3e-20 71.2 3.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCH59726.1 - 1.7e-12 47.4 0.1 3.2e-06 27.3 0.0 5.5 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.17 CCH59726.1 - 7.6e-10 38.0 1.2 0.036 14.1 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 CCH59726.1 - 0.0022 18.3 2.7 1.8 9.1 0.0 4.9 4 2 1 5 5 5 1 HEAT-like repeat DUF2435 PF10363.4 CCH59726.1 - 0.41 10.5 12.2 14 5.6 0.0 5.7 5 2 2 7 7 7 0 Protein of unknown function (DUF2435) Cmc1 PF08583.5 CCH59727.1 - 5.4e-20 70.9 5.0 6.7e-20 70.6 3.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1903 PF08991.5 CCH59727.1 - 0.091 12.9 3.5 0.86 9.8 2.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1903) CHCH PF06747.8 CCH59727.1 - 0.23 11.4 2.6 0.47 10.4 1.6 1.7 1 1 0 1 1 1 0 CHCH domain COX17 PF05051.8 CCH59727.1 - 0.52 10.3 2.9 15 5.6 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Abhydrolase_1 PF00561.15 CCH59728.1 - 1.3e-24 86.9 0.0 2.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CCH59728.1 - 1.5e-19 69.0 0.1 3e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCH59728.1 - 5.1e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH59728.1 - 0.00015 21.5 0.0 0.0016 18.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCH59728.1 - 0.016 14.6 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase IL3 PF02059.10 CCH59728.1 - 0.032 14.2 0.1 0.032 14.2 0.1 2.2 2 0 0 2 2 2 0 Interleukin-3 Cutinase PF01083.17 CCH59728.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Cutinase Snf7 PF03357.16 CCH59729.1 - 1.3e-47 161.3 18.9 1.3e-47 161.3 13.1 2.0 2 0 0 2 2 2 1 Snf7 DASH_Dad4 PF08650.5 CCH59729.1 - 0.0025 17.6 0.9 0.006 16.4 0.6 1.7 1 0 0 1 1 1 1 DASH complex subunit Dad4 Snapin_Pallidin PF14712.1 CCH59729.1 - 0.0085 16.3 17.8 0.0099 16.1 3.4 3.3 2 1 1 3 3 3 2 Snapin/Pallidin THP2 PF09432.5 CCH59729.1 - 0.015 15.1 3.4 0.043 13.6 2.4 1.8 1 0 0 1 1 1 0 Tho complex subunit THP2 Cob_adeno_trans PF01923.13 CCH59729.1 - 0.02 14.6 1.5 0.02 14.6 1.0 2.0 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Prefoldin_2 PF01920.15 CCH59729.1 - 1.4 8.7 17.8 0.48 10.2 1.4 3.6 3 1 0 3 3 3 0 Prefoldin subunit DUF948 PF06103.6 CCH59729.1 - 2.2 8.2 8.4 10 6.0 2.0 3.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) LUC7 PF03194.10 CCH59729.1 - 4.4 6.7 15.1 0.98 8.8 2.5 2.1 1 1 1 2 2 2 0 LUC7 N_terminus DUF3573 PF12097.3 CCH59729.1 - 7.5 5.0 10.4 12 4.3 5.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) SNARE PF05739.14 CCH59730.1 - 2.9e-18 65.3 2.7 2.9e-18 65.3 1.9 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCH59730.1 - 1.4e-17 63.7 2.0 1.4e-17 63.7 1.4 3.2 2 1 0 3 3 3 1 Syntaxin Sed5p PF11416.3 CCH59730.1 - 2.3e-14 52.4 3.7 8e-14 50.7 2.5 2.0 1 0 0 1 1 1 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 CCH59730.1 - 0.0012 18.6 1.5 0.0012 18.6 1.0 2.2 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 CCH59730.1 - 0.0042 16.6 0.6 0.0042 16.6 0.4 2.5 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 CCH59730.1 - 0.33 10.7 4.4 0.41 10.4 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 CCH59730.1 - 3.4 8.1 9.1 0.49 10.8 0.2 3.4 3 2 2 5 5 5 0 Syntaxin 6, N-terminal Peptidase_M50B PF13398.1 CCH59731.1 - 0.0025 17.2 1.0 0.0028 17.0 0.7 1.0 1 0 0 1 1 1 1 Peptidase M50B-like Pex24p PF06398.6 CCH59731.1 - 0.15 10.8 1.3 0.18 10.5 0.9 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin SDA1 PF05285.7 CCH59732.1 - 0.084 12.1 22.8 0.13 11.5 15.8 1.3 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.5 CCH59732.1 - 0.18 12.0 21.5 4.7 7.5 12.3 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 CCH59732.1 - 8.4 5.5 20.7 3.8 6.6 9.8 2.2 2 0 0 2 2 2 0 NOA36 protein MUG113 PF13455.1 CCH59733.1 - 6.8e-10 39.2 0.1 1.1e-08 35.4 0.1 2.3 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CCH59733.1 - 3.6e-08 33.7 0.9 3.6e-05 24.0 0.6 2.6 1 1 0 1 1 1 1 T5orf172 domain zf-TRM13_CCCH PF11722.3 CCH59733.1 - 0.059 12.7 0.3 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein Sigma_reg_C PF13791.1 CCH59733.1 - 0.19 11.7 0.6 0.34 10.9 0.4 1.5 1 1 0 1 1 1 0 Sigma factor regulator C-terminal WD40 PF00400.27 CCH59734.1 - 1.2e-29 101.0 1.1 4.6e-09 35.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCH59734.1 - 4.3e-05 23.3 1.0 0.18 11.5 0.1 2.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Polyhedrin PF00738.13 CCH59734.1 - 0.029 13.4 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Polyhedrin 4F5 PF04419.9 CCH59735.1 - 3.4e-08 34.0 14.3 3.4e-08 34.0 9.9 2.1 2 0 0 2 2 2 1 4F5 protein family FAM110_N PF14161.1 CCH59735.1 - 0.68 10.2 4.8 0.84 9.9 3.2 1.4 1 1 0 1 1 1 0 Centrosome-associated N terminus PP28 PF10252.4 CCH59735.1 - 2.8 8.0 17.9 3 7.9 3.7 2.1 1 1 1 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DDRGK PF09756.4 CCH59735.1 - 3 7.2 13.1 3.4 7.0 9.1 1.0 1 0 0 1 1 1 0 DDRGK domain DEAD PF00270.24 CCH59736.1 - 4.9e-32 110.7 1.5 1.1e-31 109.5 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59736.1 - 5.7e-22 77.3 0.1 1.7e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH59736.1 - 2.6e-08 33.9 0.0 2.6e-08 33.9 0.0 2.7 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCH59736.1 - 0.011 14.7 0.1 0.011 14.7 0.1 2.5 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CCH59736.1 - 0.042 14.0 1.1 0.32 11.1 0.3 2.7 1 1 0 2 2 2 0 AAA domain DUF2884 PF11101.3 CCH59737.1 - 0.11 11.7 2.5 0.094 12.0 0.2 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2884) Pkinase PF00069.20 CCH59738.1 - 2.2e-52 177.7 0.1 2.7e-52 177.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59738.1 - 2.8e-22 79.0 0.1 1.7e-21 76.4 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH59738.1 - 0.0011 18.7 0.5 0.0032 17.2 0.4 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ldh_1_N PF00056.18 CCH59739.1 - 1.2e-43 148.3 0.1 2.1e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCH59739.1 - 1.7e-23 83.2 0.0 2.5e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCH59739.1 - 1.8e-06 26.8 0.0 2.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCH59739.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCH59739.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_4 PF02056.11 CCH59739.1 - 0.089 12.1 0.1 6.2 6.0 0.0 2.4 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase Arf PF00025.16 CCH59740.1 - 3e-41 140.5 0.3 3.6e-41 140.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCH59740.1 - 2.2e-13 49.9 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCH59740.1 - 1.4e-12 47.0 3.1 3e-08 32.7 0.3 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CCH59740.1 - 1.1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCH59740.1 - 1.3e-11 44.0 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCH59740.1 - 3.3e-09 37.2 0.0 4.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCH59740.1 - 1.3e-07 31.0 0.0 1.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCH59740.1 - 1e-05 25.0 0.2 0.0013 18.2 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.13 CCH59740.1 - 0.00038 19.5 0.1 0.0074 15.3 0.0 2.0 2 0 0 2 2 2 1 Septin FeoB_N PF02421.13 CCH59740.1 - 0.00063 19.0 0.6 0.0091 15.2 0.4 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 CCH59740.1 - 0.00091 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CCH59740.1 - 0.0029 17.4 0.1 0.006 16.4 0.0 1.7 1 1 1 2 2 2 1 Dynamin family cobW PF02492.14 CCH59740.1 - 0.0038 16.6 1.7 1.3 8.3 0.7 2.5 2 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF1311 PF07007.7 CCH59740.1 - 0.015 15.4 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) PduV-EutP PF10662.4 CCH59740.1 - 0.015 14.7 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CCH59740.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain CdhD PF03599.11 CCH59740.1 - 0.03 12.8 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit ABC_tran PF00005.22 CCH59740.1 - 0.045 14.0 0.1 0.067 13.4 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 CCH59740.1 - 0.055 13.1 0.1 0.056 13.1 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CCH59740.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 CCH59740.1 - 0.082 12.0 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CCH59740.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCH59740.1 - 0.12 13.2 0.2 0.23 12.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 CCH59740.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 GATA PF00320.22 CCH59741.1 - 4.6e-15 54.6 2.8 9.5e-15 53.6 1.1 2.2 2 0 0 2 2 2 1 GATA zinc finger WD40 PF00400.27 CCH59742.1 - 1.8e-18 65.6 5.3 2.3e-06 27.2 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCH59742.1 - 2.3e-18 65.8 0.1 6.1e-18 64.4 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nop14 PF04147.7 CCH59742.1 - 3 5.6 23.9 3 5.6 9.6 2.3 2 0 0 2 2 2 0 Nop14-like family FLO_LFY PF01698.11 CCH59742.1 - 4.5 6.0 13.4 0.15 10.9 3.6 2.2 2 1 1 3 3 3 0 Floricaula / Leafy protein Nramp PF01566.13 CCH59743.1 - 2e-93 313.0 14.9 2.7e-93 312.5 10.3 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4131 PF13567.1 CCH59743.1 - 0.24 10.7 4.0 1 8.7 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1430 PF07242.6 CCH59743.1 - 0.29 11.2 0.0 0.29 11.2 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1430) Kdo PF06293.9 CCH59744.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Toxin_40 PF15520.1 CCH59746.1 - 2.2 7.7 10.5 0.89 8.9 1.7 2.1 1 1 1 2 2 2 0 Putative toxin 40 Ribosomal_L15e PF00827.12 CCH59747.1 - 1.7e-90 301.7 12.6 1.9e-90 301.5 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.13 CCH59748.1 - 1.4e-119 398.8 0.0 2.1e-119 398.2 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCH59748.1 - 7.5e-26 89.9 0.1 7.8e-25 86.6 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain zf-C3HC4_3 PF13920.1 CCH59749.1 - 6.3e-07 28.9 16.1 1e-06 28.2 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.16 CCH59750.1 - 8e-81 271.7 0.0 9e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TPR_2 PF07719.12 CCH59751.1 - 2.4e-09 36.4 8.1 0.00095 18.9 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCH59751.1 - 2.9e-09 36.4 5.2 2.2e-06 27.1 0.4 3.6 2 2 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCH59751.1 - 2.8e-08 32.9 6.3 0.00013 21.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH59751.1 - 1.2e-06 28.3 3.4 0.0027 17.5 0.1 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCH59751.1 - 6.5e-05 22.4 15.4 0.0064 16.1 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH59751.1 - 0.00018 21.0 0.3 4.6 7.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCH59751.1 - 0.001 19.1 10.1 0.47 10.6 0.6 3.5 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CCH59751.1 - 0.0025 18.1 0.4 11 6.5 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59751.1 - 0.015 15.9 0.0 0.18 12.5 0.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCH59751.1 - 0.044 14.4 0.0 18 6.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.12 CCH59752.1 - 1e-103 347.5 32.7 1.2e-103 347.3 22.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3814 PF12769.2 CCH59752.1 - 0.024 14.8 0.8 0.57 10.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) DNA_mis_repair PF01119.14 CCH59753.1 - 1.6e-24 85.6 0.1 5.1e-24 84.0 0.1 1.9 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCH59753.1 - 2.9e-14 52.8 0.2 7.9e-14 51.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCH59753.1 - 5.3e-10 39.0 0.0 1.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E1-E2_ATPase PF00122.15 CCH59754.1 - 8.6e-18 64.2 0.0 2.7e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 CCH59754.1 - 7.2e-16 59.2 1.6 4.8e-12 46.7 0.6 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH59754.1 - 1.3e-14 54.8 0.0 1.5e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH59754.1 - 3.3e-13 49.4 0.0 1.2e-12 47.6 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DnaJ PF00226.26 CCH59755.1 - 3.4e-25 87.5 1.3 6e-25 86.7 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3671 PF12420.3 CCH59755.1 - 0.0075 16.2 0.5 1.1 9.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF633 PF04816.7 CCH59755.1 - 0.032 13.5 0.1 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) Thi4 PF01946.12 CCH59756.1 - 1.5e-97 325.1 0.1 1.8e-97 324.9 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CCH59756.1 - 9.2e-08 31.3 0.6 5.6e-07 28.7 0.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCH59756.1 - 1.3e-05 24.3 0.3 2.1e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 CCH59756.1 - 0.00011 21.2 1.7 0.0014 17.6 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CCH59756.1 - 0.00011 22.1 0.3 0.00029 20.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCH59756.1 - 0.00039 20.2 0.1 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCH59756.1 - 0.00041 20.2 0.0 0.0028 17.5 0.3 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH59756.1 - 0.0023 18.0 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCH59756.1 - 0.0027 16.2 0.6 0.0045 15.5 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 CCH59756.1 - 0.0043 16.1 0.1 0.0059 15.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CCH59756.1 - 0.068 12.0 0.3 0.16 10.8 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 CCH59756.1 - 0.18 10.3 0.3 0.24 9.9 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ArsA_ATPase PF02374.10 CCH59757.1 - 2.2e-115 384.9 0.0 2.5e-115 384.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CCH59757.1 - 9.6e-13 47.9 0.4 1.9e-12 47.0 0.3 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 CCH59757.1 - 0.00064 18.9 0.2 0.0016 17.7 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 CCH59757.1 - 0.0015 18.5 0.0 0.011 15.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 CCH59757.1 - 0.017 14.6 0.1 0.25 10.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CCH59757.1 - 0.036 13.4 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CCH59757.1 - 0.07 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 CCH59757.1 - 0.13 11.3 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin EVI2A PF05399.6 CCH59758.1 - 0.22 10.7 4.4 0.33 10.1 3.1 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Neur_chan_memb PF02932.11 CCH59758.1 - 0.56 10.0 11.3 0.7 9.7 7.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BUD22 PF09073.5 CCH59758.1 - 2.1 7.3 32.2 2.5 7.0 22.3 1.0 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 CCH59758.1 - 3.1 6.1 27.0 3.7 5.9 18.7 1.0 1 0 0 1 1 1 0 Daxx Family Pox_A_type_inc PF04508.7 CCH59758.1 - 3.4 7.6 7.3 21 5.2 0.2 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CLP_protease PF00574.18 CCH59758.1 - 4 7.0 7.7 0.58 9.7 1.1 2.2 2 0 0 2 2 2 0 Clp protease DUF3827 PF12877.2 CCH59758.1 - 9.2 4.2 15.7 11 3.9 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Peptidase_S64 PF08192.6 CCH59758.1 - 9.7 4.3 13.3 10 4.2 9.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Striatin PF08232.7 CCH59759.1 - 0.0014 18.9 15.4 0.0022 18.3 10.7 1.2 1 0 0 1 1 1 1 Striatin family Hid1 PF12722.2 CCH59759.1 - 0.0048 14.6 5.4 0.0057 14.4 3.8 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.14 CCH59759.1 - 0.1 10.4 13.2 0.11 10.3 9.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CCH59759.1 - 0.11 11.4 20.5 0.14 11.1 14.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_27 PF13514.1 CCH59759.1 - 0.3 8.7 11.2 0.38 8.3 7.8 1.2 1 0 0 1 1 1 0 AAA domain LXG PF04740.7 CCH59759.1 - 0.47 10.2 19.5 0.58 9.9 13.5 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Atg14 PF10186.4 CCH59759.1 - 0.6 9.0 14.0 0.78 8.6 9.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-H PF05837.7 CCH59759.1 - 1 9.5 17.9 1.4 9.1 4.5 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4515 PF14988.1 CCH59759.1 - 1.2 8.7 25.8 1.6 8.3 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) IncA PF04156.9 CCH59759.1 - 1.8 8.1 22.3 2.4 7.7 15.4 1.1 1 0 0 1 1 1 0 IncA protein CpXC PF14353.1 CCH59759.1 - 2 8.4 8.3 3 7.8 3.6 2.0 1 1 1 2 2 2 0 CpXC protein TMF_DNA_bd PF12329.3 CCH59759.1 - 2.3 8.0 29.3 1.5 8.6 13.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding COG2 PF06148.6 CCH59759.1 - 2.5 7.9 13.4 8.1 6.3 9.3 1.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1845 PF08900.6 CCH59759.1 - 3.5 6.8 7.7 0.42 9.8 1.5 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF1845) DUF3450 PF11932.3 CCH59759.1 - 3.6 6.7 21.3 4.5 6.4 12.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3016 PF11454.3 CCH59759.1 - 3.9 7.0 8.3 1.4 8.5 2.2 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF3016) Cut12 PF11500.3 CCH59759.1 - 3.9 7.1 18.5 0.057 13.1 3.5 2.2 1 1 1 2 2 2 0 Spindle pole body formation-associated protein Exonuc_VII_L PF02601.10 CCH59759.1 - 5.7 6.0 12.6 7.3 5.6 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4613 PF15390.1 CCH59759.1 - 9.4 4.2 11.0 12 3.9 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) TP53IP5 PF15331.1 CCH59759.1 - 9.9 6.0 10.4 14 5.5 7.2 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Ribosomal_S8 PF00410.14 CCH59760.1 - 3.7e-20 72.0 0.0 4.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 zf-met PF12874.2 CCH59761.1 - 2.4e-06 27.5 2.7 4.5e-06 26.6 1.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCH59761.1 - 0.017 15.2 2.3 0.035 14.2 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Yippee-Mis18 PF03226.9 CCH59761.1 - 0.11 12.5 0.1 0.23 11.5 0.0 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_2 PF12756.2 CCH59761.1 - 0.12 12.5 1.5 0.23 11.5 1.1 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PNK3P PF08645.6 CCH59762.1 - 8.8e-43 145.4 2.0 1.2e-42 145.0 1.4 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF3024 PF11225.3 CCH59762.1 - 0.026 14.3 0.2 0.066 13.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) PGP_phosphatase PF09419.5 CCH59762.1 - 0.085 12.2 1.3 0.099 11.9 0.1 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase DUF4116 PF13475.1 CCH59762.1 - 0.16 11.4 2.4 2 7.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) PAP_assoc PF03828.14 CCH59762.1 - 0.2 11.6 0.1 0.2 11.6 0.0 2.4 2 2 0 2 2 2 0 Cid1 family poly A polymerase PCI PF01399.22 CCH59763.1 - 1.8e-17 63.5 2.0 3.8e-17 62.5 0.3 2.5 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 CCH59763.1 - 1.6e-05 25.3 0.1 0.23 12.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH59763.1 - 0.00036 20.4 3.1 0.41 10.6 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCH59763.1 - 0.0049 15.9 2.3 0.0082 15.2 0.1 2.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH59763.1 - 0.017 15.0 0.5 14 5.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCH59763.1 - 0.05 13.4 0.1 6.4 6.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCH59763.1 - 0.24 11.9 1.4 18 6.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DDRGK PF09756.4 CCH59763.1 - 0.26 10.6 3.5 0.087 12.2 0.2 1.9 2 0 0 2 2 2 0 DDRGK domain FIVAR PF07554.8 CCH59763.1 - 0.33 11.2 4.4 17 5.8 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain PMT PF02366.13 CCH59764.1 - 7.2e-72 241.6 19.5 7.2e-72 241.6 13.5 2.7 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCH59764.1 - 2e-42 144.9 0.0 5.5e-42 143.4 0.0 1.8 1 0 0 1 1 1 1 MIR domain CDC45 PF02724.9 CCH59764.1 - 0.34 8.8 5.0 0.56 8.1 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.10 CCH59764.1 - 0.43 9.7 6.5 0.75 8.9 4.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PAT1 PF09770.4 CCH59764.1 - 1.2 7.3 23.7 1.6 6.8 16.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GET2 PF08690.5 CCH59764.1 - 8.9 5.4 9.6 1 8.5 0.4 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 UBX PF00789.15 CCH59765.1 - 8.3e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain LAM_C PF12544.3 CCH59765.1 - 0.31 11.0 1.7 0.5 10.4 1.2 1.3 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Prenyltrans PF00432.16 CCH59766.1 - 2e-30 103.9 9.5 1.9e-09 36.9 0.1 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCH59766.1 - 1.2e-17 64.3 0.0 1.7e-09 38.0 0.0 2.8 1 1 1 2 2 2 2 Prenyltransferase-like Nup84_Nup100 PF04121.8 CCH59768.1 - 8.6e-192 638.4 31.4 3.6e-190 633.1 21.8 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup96 PF12110.3 CCH59768.1 - 0.0023 17.0 2.0 0.22 10.5 0.5 3.2 2 1 0 2 2 2 2 Nuclear protein 96 Ribosomal_L6 PF00347.18 CCH59769.1 - 1.6e-26 92.5 11.1 1.3e-13 51.2 2.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 CCH59769.1 - 0.0014 17.7 0.4 0.0033 16.6 0.1 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) DUF1762 PF08574.5 CCH59770.1 - 1.6e-17 63.6 8.8 1.6e-17 63.6 6.1 4.8 4 2 0 4 4 4 1 Protein of unknown function (DUF1762) adh_short PF00106.20 CCH59771.1 - 4.8e-23 81.8 0.0 6.1e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH59771.1 - 7.8e-08 32.1 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCH59771.1 - 3.4e-06 27.0 0.0 4.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 CCH59771.1 - 0.042 12.5 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCH59771.1 - 0.044 13.2 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1890 PF09001.6 CCH59771.1 - 0.069 13.1 0.2 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) RNase_PH PF01138.16 CCH59772.1 - 3.4e-14 53.2 0.8 5.6e-14 52.5 0.6 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCH59772.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Tropomyosin_1 PF12718.2 CCH59773.1 - 0.046 13.5 4.0 0.059 13.2 2.8 1.1 1 0 0 1 1 1 0 Tropomyosin like Med9 PF07544.8 CCH59773.1 - 0.056 13.1 3.2 0.99 9.1 0.2 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 CCH59773.1 - 0.1 12.1 0.3 0.1 12.1 0.2 1.8 2 0 0 2 2 2 0 Septum formation initiator DUF676 PF05057.9 CCH59774.1 - 1.8e-58 197.4 0.0 3.2e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CCH59774.1 - 0.0066 16.0 0.0 0.02 14.4 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) LCAT PF02450.10 CCH59774.1 - 0.014 14.3 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CCH59774.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CCH59774.1 - 0.027 14.0 0.0 0.087 12.3 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein RF-1 PF00472.15 CCH59775.1 - 6e-37 125.9 5.2 1.2e-36 124.9 3.6 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CCH59775.1 - 5.2e-27 93.8 0.0 1.5e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 PCRF domain GCD14 PF08704.5 CCH59775.1 - 0.054 12.9 1.0 0.13 11.7 0.2 2.0 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DUF4635 PF15466.1 CCH59775.1 - 1.2 8.4 8.1 0.094 12.0 0.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4635) Pkinase PF00069.20 CCH59776.1 - 3.7e-72 242.5 0.0 4.2e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59776.1 - 2.2e-32 112.1 0.0 2.9e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59776.1 - 0.00047 19.2 0.0 0.00066 18.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH59776.1 - 0.00077 19.2 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCH59776.1 - 0.019 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2418 PF10332.4 CCH59777.1 - 4.5e-20 71.7 1.9 4.5e-20 71.7 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ADH_zinc_N_2 PF13602.1 CCH59778.1 - 1.7e-09 38.5 0.0 3.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH59778.1 - 7.8e-06 25.6 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SH3_9 PF14604.1 CCH59779.1 - 8.2e-07 28.5 0.1 1.7e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH59779.1 - 1.5e-06 27.5 0.1 2.8e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCH59779.1 - 1.8e-06 27.2 0.5 5.7e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 SH3 domain Transglut_core PF01841.14 CCH59779.1 - 0.00044 20.4 0.0 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF4124 PF13511.1 CCH59779.1 - 0.0066 16.4 0.0 0.035 14.1 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) Med5 PF08689.5 CCH59780.1 - 9.1e-211 702.2 105.9 2.1e-178 595.0 53.0 3.0 1 1 2 3 3 3 3 Mediator complex subunit Med5 zf-Tim10_DDP PF02953.10 CCH59781.1 - 1.4e-19 69.1 2.8 1.8e-19 68.7 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Sec34 PF04136.10 CCH59781.1 - 0.039 13.6 0.2 0.059 13.0 0.1 1.3 1 1 0 1 1 1 0 Sec34-like family DUF1399 PF07173.7 CCH59782.1 - 0.077 13.2 1.1 0.1 12.8 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1399) SRX PF09201.5 CCH59782.1 - 0.33 10.5 6.2 0.76 9.4 2.7 2.6 1 1 0 2 2 2 0 SRX DUF496 PF04363.7 CCH59782.1 - 1.2 9.0 5.4 0.74 9.6 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF496) Gly-zipper_Omp PF13488.1 CCH59784.1 - 0.38 10.4 4.6 0.72 9.5 3.2 1.3 1 0 0 1 1 1 0 Glycine zipper Elf1 PF05129.8 CCH59784.1 - 0.38 10.4 0.0 0.92 9.2 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Ribosomal_L22 PF00237.14 CCH59785.1 - 6.7e-19 67.7 0.0 1.7e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.6 CCH59786.1 - 1.2e-69 233.1 0.6 1.6e-69 232.8 0.4 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 Bax1-I PF01027.15 CCH59786.1 - 0.98 8.9 12.1 0.41 10.2 0.6 2.5 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF4064 PF13273.1 CCH59786.1 - 7.9 6.6 9.6 0.67 10.0 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_S3_C PF00189.15 CCH59787.1 - 1.3e-15 57.3 0.1 2.7e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CCH59787.1 - 7.6e-12 44.6 0.2 3e-11 42.7 0.2 1.9 2 0 0 2 2 2 1 KH domain KR PF08659.5 CCH59788.1 - 1.7e-05 24.5 0.0 4.4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Macoilin PF09726.4 CCH59788.1 - 0.025 12.9 7.4 0.034 12.4 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 CCH59789.1 - 2.8e-11 42.8 3.2 0.0016 18.2 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat CNH PF00780.17 CCH59789.1 - 0.017 14.5 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 CNH domain Pkinase PF00069.20 CCH59790.1 - 1.7e-62 210.8 0.0 3.4e-62 209.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59790.1 - 1.1e-20 73.7 0.0 1.9e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59790.1 - 0.069 12.0 0.0 0.63 8.9 0.0 2.3 3 0 0 3 3 3 0 Kinase-like Ribosomal_L11_N PF03946.9 CCH59791.1 - 5.1e-25 86.6 0.2 7.3e-25 86.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCH59791.1 - 1.7e-24 85.7 0.2 1.7e-24 85.7 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain UCH PF00443.24 CCH59792.1 - 1.4e-55 188.3 3.8 1.4e-55 188.3 2.6 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH59792.1 - 7.9e-17 61.6 5.9 7.9e-17 61.6 4.1 3.6 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Prenyltrans PF00432.16 CCH59792.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat zf-H2C2_2 PF13465.1 CCH59792.1 - 0.45 10.9 2.6 2.3 8.6 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain Tim17 PF02466.14 CCH59793.1 - 1.1e-48 164.5 3.7 1.5e-48 164.0 2.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family COX1 PF00115.15 CCH59793.1 - 0.054 12.1 0.3 0.079 11.5 0.2 1.2 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DLH PF01738.13 CCH59793.1 - 0.081 12.1 0.6 0.26 10.5 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family Arm PF00514.18 CCH59795.1 - 8.8e-28 95.1 11.4 2.3e-07 30.3 0.1 8.6 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat IBB PF01749.15 CCH59795.1 - 2.3e-08 34.0 6.8 5.4e-08 32.8 4.7 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CCH59795.1 - 1.2e-05 25.4 0.0 0.023 14.9 0.0 3.3 1 1 4 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 CCH59795.1 - 0.0011 19.3 0.2 1 9.9 0.0 4.6 5 1 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 CCH59795.1 - 0.024 14.6 0.4 2.3 8.5 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Endonuclease_5 PF04493.9 CCH59796.1 - 1.3 8.3 5.1 3.1 7.0 0.3 2.1 1 1 1 2 2 2 0 Endonuclease V Plug PF07715.10 CCH59797.1 - 0.47 10.8 5.3 4.6 7.6 1.0 3.2 3 0 0 3 3 3 0 TonB-dependent Receptor Plug Domain Baculo_LEF-2 PF03041.9 CCH59798.1 - 0.033 13.8 0.3 0.087 12.5 0.1 1.8 2 0 0 2 2 2 0 lef-2 RRM_1 PF00076.17 CCH59799.1 - 2.2e-13 49.6 0.0 6.9e-06 25.6 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59799.1 - 0.0097 15.8 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.13 CCH59800.1 - 9.8e-68 228.1 6.6 9.8e-68 228.1 4.6 2.7 2 1 0 2 2 2 1 Septin Dynamin_N PF00350.18 CCH59800.1 - 0.0043 16.8 0.1 0.0043 16.8 0.0 2.9 2 2 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 CCH59800.1 - 0.0061 16.5 1.3 0.0094 15.9 0.0 2.0 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 CCH59800.1 - 0.042 13.8 3.9 0.38 10.7 0.9 3.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CCH59800.1 - 0.099 13.4 0.4 0.99 10.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain PEMT PF04191.8 CCH59801.1 - 2.7e-51 172.1 7.6 5.8e-27 93.8 0.4 3.1 2 0 0 2 2 2 2 Phospholipid methyltransferase Arrestin_N PF00339.24 CCH59802.1 - 2.9e-17 62.8 2.3 4.5e-17 62.2 0.0 2.5 3 1 1 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCH59802.1 - 9.5e-07 28.9 1.4 9.5e-07 28.9 1.0 4.0 3 1 1 4 4 4 1 Arrestin (or S-antigen), C-terminal domain A2M PF00207.17 CCH59802.1 - 0.0047 16.4 0.4 0.36 10.4 0.1 2.5 2 0 0 2 2 2 2 Alpha-2-macroglobulin family DUF2046 PF09755.4 CCH59804.1 - 0.0044 15.9 0.2 0.0067 15.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Herpes_BLRF2 PF05812.7 CCH59804.1 - 0.064 13.0 0.4 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein SAM_2 PF07647.12 CCH59804.1 - 0.86 9.4 3.9 0.25 11.1 0.6 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) YMF19 PF02326.10 CCH59804.1 - 2.7 8.6 7.0 0.98 10.0 0.1 3.0 3 1 1 4 4 4 0 Plant ATP synthase F0 Glyco_tran_28_C PF04101.11 CCH59805.1 - 5.3e-16 58.7 0.7 1e-12 48.0 0.1 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain AAA PF00004.24 CCH59806.1 - 1.9e-43 147.8 0.0 3.8e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH59806.1 - 5.9e-07 29.2 0.0 5.6e-06 26.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCH59806.1 - 6.7e-07 29.3 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCH59806.1 - 4.4e-06 26.8 0.5 0.0003 20.9 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCH59806.1 - 2.2e-05 24.5 0.0 7.1e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCH59806.1 - 5.9e-05 23.8 0.4 0.00013 22.7 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CCH59806.1 - 0.00013 21.6 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCH59806.1 - 0.00015 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCH59806.1 - 0.00022 20.7 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCH59806.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2072 PF09845.4 CCH59806.1 - 0.0013 18.6 1.2 0.003 17.4 0.8 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_28 PF13521.1 CCH59806.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH59806.1 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCH59806.1 - 0.0029 16.7 0.0 0.0067 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 CCH59806.1 - 0.0053 16.3 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCH59806.1 - 0.0078 16.5 2.3 0.031 14.5 0.0 2.9 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.16 CCH59806.1 - 0.0088 15.2 0.2 0.024 13.7 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCH59806.1 - 0.0088 14.7 0.3 0.022 13.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus PhoH PF02562.11 CCH59806.1 - 0.012 14.8 0.0 0.045 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 CCH59806.1 - 0.025 14.0 0.0 0.15 11.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCH59806.1 - 0.027 13.8 0.1 0.1 12.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCH59806.1 - 0.029 14.5 0.0 0.076 13.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CCH59806.1 - 0.033 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Tropomyosin PF00261.15 CCH59806.1 - 0.054 12.5 2.4 0.06 12.4 0.2 1.9 2 0 0 2 2 2 0 Tropomyosin NB-ARC PF00931.17 CCH59806.1 - 0.063 12.1 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.8 CCH59806.1 - 0.063 12.1 0.2 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.7 CCH59806.1 - 0.067 12.8 0.0 0.35 10.5 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 CCH59806.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCH59806.1 - 0.13 12.3 0.1 0.58 10.2 0.0 2.2 2 1 0 2 2 1 0 Sigma-54 interaction domain MIF4G PF02854.14 CCH59807.1 - 1.3e-47 161.9 0.2 3.3e-47 160.6 0.2 1.7 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCH59807.1 - 8.7e-23 80.0 0.6 8.7e-23 80.0 0.4 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 TYW3 PF02676.9 CCH59808.1 - 1.1e-64 217.3 0.0 1.4e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 U1snRNP70_N PF12220.3 CCH59808.1 - 1.1 9.6 6.1 2.3 8.5 4.2 1.5 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Gtr1_RagA PF04670.7 CCH59809.1 - 1.3e-68 230.6 0.7 2e-68 230.0 0.5 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CCH59809.1 - 0.0013 17.9 0.0 0.0035 16.6 0.0 1.8 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF815 PF05673.8 CCH59809.1 - 0.054 12.4 0.0 0.11 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CCH59809.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AsnC_trans_reg PF01037.16 CCH59809.1 - 0.095 12.4 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AsnC family AAA_17 PF13207.1 CCH59810.1 - 2.6e-05 25.0 0.2 8.4e-05 23.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCH59810.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CCH59810.1 - 0.0052 17.0 0.7 0.02 15.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCH59810.1 - 0.0064 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 CCH59810.1 - 0.012 15.7 0.2 0.064 13.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CCH59810.1 - 0.038 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCH59810.1 - 0.056 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCH59810.1 - 0.099 12.0 0.1 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain tRNA_bind PF01588.15 CCH59811.1 - 2.5e-18 65.7 0.7 4.1e-18 64.9 0.5 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Aconitase PF00330.15 CCH59812.1 - 5.5e-180 598.7 0.0 1.1e-179 597.8 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCH59812.1 - 2e-47 160.5 0.1 4.3e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.22 CCH59813.1 - 1.4e-43 149.0 0.0 5.2e-43 147.2 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CCH59813.1 - 1.2e-27 96.2 0.1 4.7e-27 94.3 0.0 2.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Polysacc_deac_1 PF01522.16 CCH59814.1 - 5.6e-24 84.1 0.0 9.2e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GRIP PF01465.15 CCH59815.1 - 2.6e-15 55.6 0.1 7.8e-15 54.1 0.1 1.9 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.4 CCH59815.1 - 1.4e-05 24.9 18.2 1.4e-05 24.9 12.6 10.1 2 2 8 10 10 10 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 CCH59815.1 - 0.00021 20.5 83.5 0.00064 19.0 5.6 8.9 2 2 7 9 9 9 5 Reovirus sigma C capsid protein Spc7 PF08317.6 CCH59815.1 - 0.0011 17.7 15.8 0.0011 17.7 10.9 8.6 2 1 6 9 9 9 4 Spc7 kinetochore protein MscS_porin PF12795.2 CCH59815.1 - 0.0017 17.7 6.9 0.0017 17.7 4.8 8.3 1 1 8 9 9 9 2 Mechanosensitive ion channel porin domain APG6 PF04111.7 CCH59815.1 - 0.0023 17.0 15.7 0.0023 17.0 10.9 9.2 1 1 8 9 9 9 4 Autophagy protein Apg6 Fib_alpha PF08702.5 CCH59815.1 - 0.0042 17.2 18.1 0.0042 17.2 12.5 10.0 1 1 10 11 11 11 2 Fibrinogen alpha/beta chain family RasGEF PF00617.14 CCH59816.1 - 6.6e-56 189.0 0.1 6.6e-56 189.0 0.1 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCH59816.1 - 4.7e-19 68.4 0.4 4.7e-19 68.4 0.3 5.4 3 1 1 4 4 4 1 RasGEF N-terminal motif SH3_9 PF14604.1 CCH59816.1 - 5.1e-05 22.7 0.2 0.00024 20.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CCH59816.1 - 0.00011 21.4 4.0 0.00012 21.3 0.2 3.0 4 0 0 4 4 4 1 SH3 domain SH3_2 PF07653.12 CCH59816.1 - 0.00014 21.2 0.6 0.00055 19.3 0.4 1.9 1 1 0 1 1 1 1 Variant SH3 domain tRNA-synt_2 PF00152.15 CCH59817.1 - 3e-84 282.6 1.7 3e-84 282.6 1.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCH59817.1 - 2.7e-08 33.5 0.4 2.7e-08 33.5 0.3 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCH59817.1 - 0.041 13.0 1.8 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUP PF00674.13 CCH59818.1 - 0.0031 17.4 0.1 0.0048 16.8 0.1 1.2 1 0 0 1 1 1 1 DUP family Pet191_N PF10203.4 CCH59819.1 - 0.037 14.0 1.1 0.15 12.1 0.8 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 CCH59819.1 - 0.12 12.2 0.3 0.28 11.1 0.2 1.6 1 1 0 1 1 1 0 CHCH domain Pkinase PF00069.20 CCH59820.1 - 1.1e-47 162.4 0.0 4.2e-47 160.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59820.1 - 2.7e-19 69.2 0.0 7.1e-19 67.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59820.1 - 0.083 11.8 0.1 0.62 8.9 0.0 2.3 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.9 CCH59820.1 - 0.088 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribonucleas_3_3 PF14622.1 CCH59821.1 - 2e-22 79.4 0.2 3.6e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCH59821.1 - 9.4e-06 26.0 0.4 2.8e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease III domain GIT_SHD PF08518.6 CCH59822.1 - 9.6e-23 79.2 4.8 2.6e-11 42.6 0.2 3.3 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT TPP_enzyme_M PF00205.17 CCH59823.1 - 9.2e-36 122.6 0.0 3.9e-35 120.5 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCH59823.1 - 7.6e-33 113.4 0.1 1.2e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCH59823.1 - 9.3e-13 48.0 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ABC_membrane PF00664.18 CCH59824.1 - 9.2e-82 274.5 48.8 1.8e-46 158.7 12.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCH59824.1 - 6.4e-61 204.6 0.0 1.2e-29 103.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCH59824.1 - 5.2e-16 58.5 0.0 5e-06 25.8 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CCH59824.1 - 7.1e-11 42.0 0.2 0.00046 19.7 0.1 4.4 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 CCH59824.1 - 3.8e-09 36.7 1.6 0.0057 16.7 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCH59824.1 - 2.2e-08 34.9 0.0 0.012 16.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCH59824.1 - 7.2e-08 31.7 0.1 0.00054 19.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCH59824.1 - 2e-07 31.3 0.0 0.0043 17.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCH59824.1 - 6.3e-07 28.8 0.2 0.0042 16.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CCH59824.1 - 1.6e-06 28.2 0.0 0.064 13.2 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CCH59824.1 - 2.4e-06 27.4 0.0 0.0057 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CCH59824.1 - 2.9e-06 26.1 6.8 6.4e-05 21.7 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RNA_helicase PF00910.17 CCH59824.1 - 7.4e-05 22.8 0.0 0.15 12.2 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 CCH59824.1 - 0.00014 21.3 0.0 0.21 10.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 CCH59824.1 - 0.00018 20.5 0.1 0.037 12.9 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 CCH59824.1 - 0.00039 20.9 0.5 0.35 11.3 0.0 3.2 3 0 0 3 3 2 1 Miro-like protein Trp_repressor PF01371.14 CCH59824.1 - 0.0004 20.2 0.7 0.027 14.3 0.0 3.2 3 0 0 3 3 2 1 Trp repressor protein ATP-synt_ab PF00006.20 CCH59824.1 - 0.00041 19.9 0.0 0.04 13.4 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 CCH59824.1 - 0.00058 19.5 3.9 0.21 11.2 0.7 3.5 2 1 0 2 2 2 1 NACHT domain FtsK_SpoIIIE PF01580.13 CCH59824.1 - 0.0012 18.3 0.1 0.92 8.9 0.0 2.5 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_14 PF13173.1 CCH59824.1 - 0.0014 18.4 11.1 0.05 13.5 0.0 4.8 5 0 0 5 5 4 1 AAA domain AAA_5 PF07728.9 CCH59824.1 - 0.0015 18.2 0.1 2.9 7.6 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CCH59824.1 - 0.0018 17.7 0.0 0.062 12.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CCH59824.1 - 0.0018 18.2 2.6 0.43 10.5 1.2 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CCH59824.1 - 0.0027 16.8 0.0 0.57 9.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 CCH59824.1 - 0.0032 17.1 1.0 1.4 8.6 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CCH59824.1 - 0.0036 17.4 0.1 0.87 9.7 0.0 3.8 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 CCH59824.1 - 0.0047 16.5 0.0 0.62 9.5 0.0 3.1 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family Sigma54_activ_2 PF14532.1 CCH59824.1 - 0.0053 16.8 0.0 0.21 11.6 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain SbcCD_C PF13558.1 CCH59824.1 - 0.0055 16.6 0.0 1.1 9.2 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 CCH59824.1 - 0.027 14.0 1.3 2.4 7.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCH59824.1 - 0.038 13.7 0.0 4.8 7.0 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain DUF3987 PF13148.1 CCH59824.1 - 0.04 12.4 0.0 0.31 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_30 PF13604.1 CCH59824.1 - 0.063 12.8 0.0 11 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF3584 PF12128.3 CCH59824.1 - 0.08 10.2 0.1 0.29 8.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) YwiC PF14256.1 CCH59824.1 - 1.6 8.8 9.1 0.22 11.5 0.6 3.1 3 0 0 3 3 3 0 YwiC-like protein DUF87 PF01935.12 CCH59824.1 - 4.5 7.0 11.9 2.8 7.6 0.3 3.8 4 0 0 4 4 3 0 Domain of unknown function DUF87 Mog1 PF04603.7 CCH59825.1 - 3.7e-19 69.0 0.1 4.4e-18 65.5 0.1 2.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.10 CCH59826.1 - 5.2e-12 46.0 0.1 6.4e-11 42.5 0.0 2.4 2 1 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3529 PF12046.3 CCH59826.1 - 0.029 13.3 0.1 0.05 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Septin PF00735.13 CCH59827.1 - 6.3e-109 363.3 0.0 1.1e-108 362.5 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCH59827.1 - 5.8e-08 32.6 0.0 1.4e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCH59827.1 - 5.9e-07 29.4 7.3 0.00011 22.0 0.4 3.2 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 CCH59827.1 - 4e-06 26.0 0.1 4e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CCH59827.1 - 8.6e-05 21.7 1.3 0.00035 19.8 0.9 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CCH59827.1 - 0.00019 21.8 1.5 0.00024 21.5 0.1 1.8 2 0 0 2 2 1 1 Miro-like protein ABC_tran PF00005.22 CCH59827.1 - 0.0003 21.0 0.5 0.0012 19.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 CCH59827.1 - 0.00076 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 CCH59827.1 - 0.0013 18.2 0.8 0.11 11.9 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 CCH59827.1 - 0.004 16.0 0.1 0.0068 15.2 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Gasdermin PF04598.7 CCH59827.1 - 0.0049 15.6 2.0 0.0078 15.0 1.4 1.3 1 0 0 1 1 1 1 Gasdermin family MobB PF03205.9 CCH59827.1 - 0.0059 16.3 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCH59827.1 - 0.0099 16.6 0.8 0.053 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCH59827.1 - 0.015 14.7 1.0 2 7.8 0.1 2.9 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CCH59827.1 - 0.032 14.3 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CCH59827.1 - 0.042 12.7 0.1 0.075 11.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 CCH59827.1 - 0.07 12.8 1.1 0.099 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CCH59827.1 - 0.072 12.6 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CCH59827.1 - 0.082 12.1 0.9 0.4 9.9 0.2 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.15 CCH59827.1 - 0.1 11.2 0.1 0.1 11.2 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.1 CCH59827.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CCH59827.1 - 1.4 8.6 5.0 15 5.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 Aldo_ket_red PF00248.16 CCH59828.1 - 3.1e-66 223.0 0.1 3.5e-66 222.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BATS PF06968.8 CCH59829.1 - 7.6e-26 89.7 0.0 2.3e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CCH59829.1 - 3.1e-18 66.5 0.3 1.2e-17 64.5 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Mito_carr PF00153.22 CCH59830.1 - 3.5e-63 209.3 0.5 2.8e-22 78.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DHO_dh PF01180.16 CCH59831.1 - 4.1e-93 311.5 0.0 4.7e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCH59831.1 - 5.8e-09 35.2 0.0 0.00025 20.0 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.16 CCH59831.1 - 0.0079 15.8 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF885 PF05960.6 CCH59831.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Sugar_tr PF00083.19 CCH59832.1 - 2.3e-156 520.9 34.6 2.6e-156 520.7 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59832.1 - 4.6e-34 117.6 30.6 2.5e-29 102.1 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 CCH59832.1 - 4.5 6.3 8.2 0.87 8.6 1.0 3.1 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Flocculin PF00624.13 CCH59833.1 - 6.7e-52 173.0 185.6 3.1e-12 46.1 11.8 17.9 15 2 3 19 19 19 10 Flocculin repeat Tubulin-binding PF00418.14 CCH59834.1 - 0.089 12.4 0.0 0.3 10.7 0.0 1.9 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Zn_clus PF00172.13 CCH59836.1 - 0.0051 16.6 2.3 0.0051 16.6 1.6 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ran-binding PF05508.6 CCH59837.1 - 3.8e-99 331.4 15.2 3.8e-99 331.4 10.5 2.0 2 0 0 2 2 2 1 RanGTP-binding protein PBP1_TM PF14812.1 CCH59837.1 - 5.5 7.3 8.8 6.9 7.0 2.1 2.9 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Copper-fist PF00649.13 CCH59838.1 - 4e-21 73.9 1.3 4e-21 73.9 0.9 2.4 1 1 1 2 2 2 2 Copper fist DNA binding domain Glyco_transf_15 PF01793.11 CCH59839.1 - 8.8e-143 475.2 15.1 1.1e-142 474.9 10.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase E1-E2_ATPase PF00122.15 CCH59840.1 - 7.6e-79 263.9 0.4 1.4e-78 263.1 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCH59840.1 - 6.6e-46 156.1 1.2 6.6e-46 156.1 0.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCH59840.1 - 6.7e-32 111.6 0.0 1.6e-31 110.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH59840.1 - 1.2e-17 63.6 0.0 2.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCH59840.1 - 4.1e-17 62.9 0.0 9.6e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCH59840.1 - 5.7e-16 57.7 0.0 1.3e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCH59840.1 - 9.6e-06 25.3 6.9 0.00025 20.6 0.6 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Flocculin PF00624.13 CCH59841.1 - 1.6e-55 184.6 205.2 1.1e-10 41.2 13.7 26.8 21 2 2 23 23 23 10 Flocculin repeat MIP PF00230.15 CCH59842.1 - 9.5e-47 159.3 16.8 1.3e-46 158.8 11.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein SUR7 PF06687.7 CCH59842.1 - 0.012 15.2 5.4 0.97 8.9 0.5 3.0 1 1 1 2 2 2 0 SUR7/PalI family DUF3522 PF12036.3 CCH59842.1 - 0.072 12.8 0.2 0.072 12.8 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) Ndc1_Nup PF09531.5 CCH59842.1 - 0.35 9.2 2.3 0.55 8.5 1.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ADH_zinc_N PF00107.21 CCH59843.1 - 4.4e-17 61.8 0.0 7.2e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LAB_N PF07578.6 CCH59843.1 - 0.03 14.2 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain ADH_zinc_N_2 PF13602.1 CCH59843.1 - 0.046 14.6 0.0 0.089 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3333 PF11812.3 CCH59843.1 - 0.083 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) Epimerase PF01370.16 CCH59844.1 - 1.3e-15 57.5 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCH59844.1 - 1.1e-08 34.1 0.0 1.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCH59844.1 - 1.5e-08 34.9 0.0 3.2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCH59844.1 - 1e-07 31.4 0.2 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 CCH59844.1 - 4.9e-06 26.5 0.3 2.1e-05 24.5 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CCH59844.1 - 3.8e-05 22.7 0.0 0.00022 20.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CCH59844.1 - 0.0017 17.3 0.1 0.0038 16.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Fmp27 PF10344.4 CCH59844.1 - 0.0042 14.8 0.0 0.0054 14.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 KR PF08659.5 CCH59844.1 - 0.0043 16.7 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CCH59844.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 CCH59845.1 - 1.5e-17 63.8 0.0 2.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCH59845.1 - 2.1e-12 46.3 0.1 2.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCH59845.1 - 1.5e-09 38.1 0.0 4.6e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCH59845.1 - 5.5e-08 32.0 0.0 2e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCH59845.1 - 8.8e-07 28.9 0.0 2.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 CCH59845.1 - 1.8e-06 27.4 0.0 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family Polysacc_synt_2 PF02719.10 CCH59845.1 - 2.2e-05 23.5 0.0 3.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCH59845.1 - 0.00047 19.8 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Fmp27 PF10344.4 CCH59845.1 - 0.002 15.9 0.0 0.0027 15.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 RmlD_sub_bind PF04321.12 CCH59845.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 CCH59845.1 - 0.039 14.0 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sigma54_activ_2 PF14532.1 CCH59845.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain F420_oxidored PF03807.12 CCH59845.1 - 0.063 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 CCH59845.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_redisom_C PF08436.7 CCH59845.1 - 0.096 12.5 0.0 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal CRC_subunit PF08624.5 CCH59846.1 - 5.2e-26 91.2 0.0 1.1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lectin_leg-like PF03388.8 CCH59847.1 - 9.1e-37 126.3 0.0 1.3e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family SnAC PF14619.1 CCH59848.1 - 0.062 13.4 1.8 0.067 13.3 0.1 1.9 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex V-SNARE_C PF12352.3 CCH59849.1 - 3.5e-08 33.3 3.7 3.5e-08 33.3 2.6 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCH59849.1 - 8.3e-05 22.2 1.0 8.3e-05 22.2 0.7 2.2 2 1 1 3 3 3 1 Sec20 XS PF03468.9 CCH59849.1 - 0.0013 18.7 0.5 0.0029 17.5 0.2 1.7 1 1 0 1 1 1 1 XS domain DUF573 PF04504.9 CCH59849.1 - 0.13 12.5 5.4 0.14 12.4 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF573 RCC1 PF00415.13 CCH59850.1 - 8.2e-25 86.7 0.1 0.00018 21.6 0.0 6.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCH59850.1 - 1.5e-12 46.7 3.0 1.1e-05 24.8 0.2 3.8 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.6 CCH59851.1 - 8.1e-60 201.8 10.4 9.7e-60 201.6 7.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3596 PF12167.3 CCH59851.1 - 0.0044 16.5 0.7 0.31 10.6 0.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3596) DUF3410 PF11890.3 CCH59851.1 - 0.048 13.3 0.7 0.048 13.3 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) MerR_1 PF13411.1 CCH59851.1 - 0.071 12.8 0.6 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF2576 PF10845.3 CCH59851.1 - 0.12 11.5 0.5 4 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) DUF1732 PF08340.6 CCH59851.1 - 0.31 10.8 8.5 0.27 11.0 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) Mitofilin PF09731.4 CCH59851.1 - 0.34 9.5 8.0 0.47 9.0 5.6 1.3 1 1 0 1 1 1 0 Mitochondrial inner membrane protein FlaC_arch PF05377.6 CCH59851.1 - 0.35 10.7 6.1 5.8 6.8 0.2 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2854 PF11016.3 CCH59851.1 - 0.49 9.9 3.3 2.1 7.8 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) Baculo_PEP_C PF04513.7 CCH59851.1 - 0.8 9.5 5.7 2.1 8.1 0.6 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 CCH59851.1 - 0.86 9.4 8.2 0.27 11.1 2.2 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1451 PF07295.6 CCH59851.1 - 0.96 9.2 5.6 0.63 9.8 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF2524 PF10732.4 CCH59851.1 - 1 9.5 5.8 0.77 9.9 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) Syntaxin PF00804.20 CCH59851.1 - 4.6 7.4 16.6 6.2 7.0 4.3 3.0 1 1 1 2 2 2 0 Syntaxin Ribosomal_L16 PF00252.13 CCH59852.1 - 1.3e-33 115.6 0.1 1.6e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e OTU PF02338.14 CCH59853.1 - 1.1e-13 51.7 0.0 1.9e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease FERM_N PF09379.5 CCH59853.1 - 0.26 11.3 1.4 1 9.4 0.1 2.5 3 1 0 3 3 3 0 FERM N-terminal domain USP8_dimer PF08969.6 CCH59854.1 - 4.4e-07 29.8 3.4 8.2e-07 28.9 2.3 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain GRAM PF02893.15 CCH59855.1 - 7.7e-16 57.3 0.4 2.4e-15 55.7 0.3 1.9 1 0 0 1 1 1 1 GRAM domain Med14 PF08638.6 CCH59856.1 - 4.8e-57 192.3 5.7 1.4e-56 190.8 3.9 1.9 1 0 0 1 1 1 1 Mediator complex subunit MED14 rRNA_processing PF08524.6 CCH59857.1 - 1.2e-41 141.9 42.6 1.6e-41 141.5 29.6 1.1 1 0 0 1 1 1 1 rRNA processing Vfa1 PF08432.5 CCH59857.1 - 8.9 6.2 27.8 12 5.8 19.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PPR_2 PF13041.1 CCH59858.1 - 4.1e-06 26.6 5.0 3 7.9 0.1 6.2 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.15 CCH59858.1 - 0.00031 20.4 1.6 3.2 7.9 0.0 6.5 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.1 CCH59858.1 - 0.00045 20.2 0.5 4.6 7.7 0.0 6.0 7 0 0 7 7 7 1 Pentatricopeptide repeat domain Sugar_tr PF00083.19 CCH59859.1 - 2.9e-63 214.0 29.4 4.8e-63 213.3 20.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59859.1 - 2.1e-23 82.6 37.4 1.8e-22 79.5 16.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Actin PF00022.14 CCH59860.1 - 5.2e-161 535.4 0.0 6e-161 535.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CCH59860.1 - 0.044 14.1 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ras PF00071.17 CCH59861.1 - 1.1e-64 216.7 0.8 1.3e-64 216.5 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH59861.1 - 3.4e-20 72.7 0.1 5.3e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH59861.1 - 6.9e-18 64.4 0.2 8.9e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCH59861.1 - 3.3e-07 29.6 0.7 4.4e-07 29.2 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH59861.1 - 2.2e-05 23.9 0.1 4.4e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCH59861.1 - 7.3e-05 22.7 0.1 0.00011 22.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCH59861.1 - 0.0011 18.1 0.1 0.0015 17.7 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCH59861.1 - 0.0059 16.7 0.0 0.014 15.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 CCH59861.1 - 0.0079 16.3 0.1 0.14 12.3 0.0 2.4 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCH59861.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 CCH59861.1 - 0.027 13.5 0.1 0.14 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin FeoB_N PF02421.13 CCH59861.1 - 0.044 13.0 0.2 0.26 10.5 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CCH59861.1 - 0.048 13.1 0.1 0.4 10.1 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CCH59861.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CCH59861.1 - 0.061 13.0 0.0 0.087 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH59861.1 - 0.072 13.0 0.2 0.21 11.5 0.1 1.8 2 1 0 3 3 3 0 AAA ATPase domain PIG-F PF06699.6 CCH59862.1 - 3.2 7.6 8.4 0.74 9.7 0.8 2.2 1 1 0 2 2 2 0 GPI biosynthesis protein family Pig-F ETF_alpha PF00766.14 CCH59863.1 - 4e-36 122.4 0.1 7.8e-36 121.5 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CCH59863.1 - 3.6e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_18 PF13238.1 CCH59864.1 - 1.6e-10 41.3 0.5 2e-07 31.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH59864.1 - 3.3e-09 37.6 0.3 4.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCH59864.1 - 1.5e-05 24.9 0.0 0.00078 19.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCH59864.1 - 4.5e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CCH59864.1 - 0.00022 21.3 0.0 0.0007 19.7 0.0 1.9 2 0 0 2 2 1 1 RNA helicase ADK PF00406.17 CCH59864.1 - 0.00025 20.9 0.4 0.3 10.9 0.0 2.4 2 0 0 2 2 2 2 Adenylate kinase KTI12 PF08433.5 CCH59864.1 - 0.00025 20.3 0.0 0.0011 18.2 0.0 2.0 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 CCH59864.1 - 0.00033 20.6 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CCH59864.1 - 0.0004 19.6 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 CCH59864.1 - 0.001 19.2 0.0 0.0029 17.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCH59864.1 - 0.0012 18.7 0.6 0.01 15.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 CCH59864.1 - 0.0017 17.5 0.0 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CCH59864.1 - 0.0022 18.1 0.0 0.0056 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCH59864.1 - 0.0025 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 CCH59864.1 - 0.0035 17.0 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 NTPase Sigma54_activat PF00158.21 CCH59864.1 - 0.0046 16.4 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 CCH59864.1 - 0.0061 16.4 0.2 0.023 14.6 0.0 2.0 2 1 0 2 2 1 1 Cytidylate kinase-like family PRK PF00485.13 CCH59864.1 - 0.0066 16.0 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 CCH59864.1 - 0.0076 16.1 0.3 0.021 14.7 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 CCH59864.1 - 0.0092 15.6 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CCH59864.1 - 0.0093 14.7 0.0 0.026 13.3 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_24 PF13479.1 CCH59864.1 - 0.014 15.0 0.0 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCH59864.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.7 CCH59864.1 - 0.016 14.8 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 CCH59864.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.15 CCH59864.1 - 0.02 14.5 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase RuvB_N PF05496.7 CCH59864.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 CCH59864.1 - 0.025 14.0 0.1 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 CCH59864.1 - 0.025 14.1 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 CCH59864.1 - 0.026 14.1 0.0 0.085 12.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 CCH59864.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Guanylate_kin PF00625.16 CCH59864.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase GTP_EFTU PF00009.22 CCH59864.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 CCH59864.1 - 0.054 12.3 0.0 0.091 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 CCH59864.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 CCH59864.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SRPRB PF09439.5 CCH59864.1 - 0.068 12.3 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 CCH59864.1 - 0.079 12.3 0.0 0.2 11.0 0.0 1.6 2 0 0 2 2 1 0 AAA domain SMC_N PF02463.14 CCH59864.1 - 0.082 12.1 0.3 0.18 11.0 0.1 1.6 2 0 0 2 2 1 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CCH59864.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MCM PF00493.18 CCH59864.1 - 0.11 11.2 0.3 0.48 9.1 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family ATP_bind_1 PF03029.12 CCH59864.1 - 0.12 11.9 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CCH59864.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SKI PF01202.17 CCH59864.1 - 0.12 12.2 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase CobU PF02283.11 CCH59864.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_23 PF13476.1 CCH59864.1 - 1.1 9.5 9.9 2.5 8.3 6.7 1.8 1 1 0 1 1 1 0 AAA domain DUF4653 PF15546.1 CCH59865.1 - 0.036 13.3 0.7 0.048 12.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) TrbH PF07283.6 CCH59865.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TrbH ICL PF00463.16 CCH59866.1 - 3.4e-172 573.3 0.2 4e-172 573.1 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCH59866.1 - 6.5e-11 41.9 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase KLRAQ PF10205.4 CCH59867.1 - 0.031 14.3 1.9 0.031 14.3 1.3 2.5 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Peptidase_M24 PF00557.19 CCH59868.1 - 7.6e-56 188.9 0.1 9.8e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCH59868.1 - 2.3e-24 85.2 0.0 2.5e-23 81.9 0.0 2.4 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain UCH PF00443.24 CCH59869.1 - 1.5e-11 43.9 1.6 2.4e-11 43.2 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCH59869.1 - 6.1e-09 35.8 0.5 1.1e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF771 PF05595.6 CCH59869.1 - 0.061 13.2 0.6 0.061 13.2 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF771) JAB PF01398.16 CCH59870.1 - 1.5e-34 118.1 0.2 3.4e-34 117.0 0.2 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCH59870.1 - 2.6e-24 85.5 3.7 2.6e-24 85.5 2.6 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CCH59870.1 - 8.9e-09 34.8 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCH59870.1 - 0.047 13.1 2.1 0.1 12.0 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) PPI_Ypi1 PF07491.6 CCH59871.1 - 2.3e-10 39.9 0.9 4.7e-10 38.9 0.6 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor Hydrolase_6 PF13344.1 CCH59872.1 - 0.025 14.4 0.1 0.08 12.8 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CDI PF02234.14 CCH59872.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor DUF3440 PF11922.3 CCH59872.1 - 1.9 8.0 6.4 9.6 5.7 2.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3440) DUF3847 PF12958.2 CCH59872.1 - 3.1 7.6 7.6 2.9 7.7 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Tubulin-binding PF00418.14 CCH59873.1 - 0.0053 16.4 0.8 0.023 14.3 0.0 2.4 3 0 0 3 3 3 1 Tau and MAP protein, tubulin-binding repeat RVT_thumb PF06817.9 CCH59873.1 - 0.023 14.2 0.0 8.3 6.0 0.0 2.8 2 0 0 2 2 2 0 Reverse transcriptase thumb domain RNase_H PF00075.19 CCH59873.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 RNase H PseudoU_synth_1 PF01416.15 CCH59874.1 - 3.5e-31 107.7 0.0 1.6e-20 73.5 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF87 PF01935.12 CCH59874.1 - 0.47 10.2 4.4 0.64 9.7 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Spore_II_R PF09551.5 CCH59875.1 - 0.18 11.8 6.4 1.7 8.7 0.3 2.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Cas_Csy4 PF09618.5 CCH59875.1 - 8.4 6.1 8.7 1.3 8.8 0.8 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) Nic96 PF04097.9 CCH59876.1 - 3.3e-200 666.3 8.1 4.1e-200 666.0 5.6 1.1 1 0 0 1 1 1 1 Nup93/Nic96 DUF3441 PF11923.3 CCH59877.1 - 1.1e-32 112.0 1.0 3.9e-32 110.1 0.1 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CCH59877.1 - 2.4e-22 79.1 0.3 2.4e-22 79.1 0.2 3.8 3 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CCH59877.1 - 1.1e-09 38.0 0.3 4.2e-09 36.1 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Bromo_TP PF07524.8 CCH59878.1 - 0.0049 16.5 0.1 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated FIVAR PF07554.8 CCH59878.1 - 1.7 8.9 13.2 0.51 10.6 6.5 2.2 2 0 0 2 2 2 0 Uncharacterised Sugar-binding Domain NUC173 PF08161.7 CCH59879.1 - 3.1e-69 232.3 4.8 9.8e-69 230.6 0.3 3.6 4 0 0 4 4 4 1 NUC173 domain HEAT PF02985.17 CCH59879.1 - 6.5e-05 22.6 0.0 6.8 7.0 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat DEAD PF00270.24 CCH59880.1 - 8.7e-42 142.4 0.5 5.1e-41 139.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59880.1 - 1.7e-26 91.8 0.2 1.3e-25 89.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH59880.1 - 0.00079 19.3 0.0 0.00079 19.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCH59880.1 - 0.095 12.8 0.5 0.67 10.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain ATP-synt_G PF04718.10 CCH59881.1 - 3.1e-26 92.0 0.2 3.6e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit zf-C3Hc3H PF13891.1 CCH59881.1 - 0.1 12.6 0.2 0.17 11.9 0.2 1.3 1 0 0 1 1 1 0 Potential DNA-binding domain Mss4 PF04421.8 CCH59882.1 - 3.5e-17 62.0 0.9 7.6e-12 44.9 0.1 2.2 1 1 1 2 2 2 2 Mss4 protein eIF-6 PF01912.13 CCH59883.1 - 1.1e-84 282.4 0.5 1.4e-84 282.1 0.3 1.1 1 0 0 1 1 1 1 eIF-6 family Pil1 PF13805.1 CCH59884.1 - 2.4e-122 407.3 0.6 4.4e-122 406.4 0.4 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 V-ATPase_H_C PF11698.3 CCH59884.1 - 0.0058 16.5 1.7 0.017 15.0 1.0 2.0 1 1 0 1 1 1 1 V-ATPase subunit H DEAD PF00270.24 CCH59885.1 - 8.1e-40 136.0 0.1 7.3e-38 129.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH59885.1 - 2.8e-20 71.9 0.0 7.7e-20 70.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCH59885.1 - 5.1e-15 54.7 0.0 1.3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCH59885.1 - 0.00021 21.1 2.4 0.0004 20.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Gp_dh_C PF02800.15 CCH59885.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain FMN_red PF03358.10 CCH59886.1 - 5.6e-10 38.9 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CCH59886.1 - 1.4e-08 34.8 0.0 2.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CCH59886.1 - 0.00038 20.0 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Ribosomal_L32p PF01783.18 CCH59887.1 - 4.3e-13 49.2 1.0 6.9e-13 48.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L32p protein family Pkinase PF00069.20 CCH59888.1 - 8.9e-66 221.6 0.1 2.4e-65 220.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59888.1 - 7.5e-24 84.1 0.0 1.5e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH59888.1 - 0.0022 17.7 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCH59888.1 - 0.006 15.5 0.0 0.021 13.7 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.15 CCH59888.1 - 0.0082 15.7 0.1 0.0082 15.7 0.1 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CCH59888.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPC25 PF06703.6 CCH59888.1 - 0.4 10.2 2.0 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) BAR PF03114.13 CCH59889.1 - 1.9e-48 164.9 2.6 2.2e-48 164.7 1.8 1.0 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.7 CCH59889.1 - 0.034 13.4 0.6 0.067 12.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) Grp1_Fun34_YaaH PF01184.14 CCH59890.1 - 1.2e-86 289.3 15.6 1.6e-86 288.9 10.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF997 PF06196.7 CCH59890.1 - 1.3 8.6 6.1 1.6 8.2 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Menin PF05053.8 CCH59890.1 - 5.2 5.1 6.9 7 4.6 4.8 1.2 1 0 0 1 1 1 0 Menin Mlo PF03094.10 CCH59890.1 - 9.1 4.2 8.5 0.12 10.4 0.4 1.9 2 0 0 2 2 2 0 Mlo family DUF4448 PF14610.1 CCH59892.1 - 3.8e-50 170.0 0.4 1.3e-26 93.2 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) EcoR124_C PF12008.3 CCH59892.1 - 3.1e-17 62.6 115.2 0.0012 18.0 5.8 9.8 1 1 9 10 10 10 9 Type I restriction and modification enzyme - subunit R C terminal PDEase_I PF00233.14 CCH59892.1 - 5.5e-07 29.5 27.5 0.56 9.9 0.2 7.1 1 1 9 11 11 11 7 3'5'-cyclic nucleotide phosphodiesterase DUF1700 PF08006.6 CCH59892.1 - 0.0013 18.0 56.3 0.92 8.7 1.4 9.6 1 1 10 11 11 11 9 Protein of unknown function (DUF1700) DUF2267 PF10025.4 CCH59892.1 - 0.0032 17.5 45.6 4.7 7.3 0.5 10.3 1 1 10 12 12 12 4 Uncharacterized conserved protein (DUF2267) BMC PF00936.14 CCH59892.1 - 0.024 14.3 8.2 2.3e+02 1.5 0.0 8.5 10 3 2 12 12 12 0 BMC domain DUF4456 PF14644.1 CCH59892.1 - 4.1 6.5 33.3 13 4.9 0.1 8.5 5 2 1 9 9 9 0 Domain of unknown function (DUF4456) Sen15 PF09631.5 CCH59893.1 - 2.5e-19 69.3 0.0 3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein ArgJ PF01960.13 CCH59894.1 - 2.6e-140 467.2 7.9 3e-140 467.0 5.5 1.0 1 0 0 1 1 1 1 ArgJ family Kinesin PF00225.18 CCH59895.1 - 2.7e-51 174.2 10.3 2.7e-51 174.2 7.2 1.8 2 1 0 2 2 2 1 Kinesin motor domain EF1G PF00647.14 CCH59896.1 - 3.3e-47 158.6 0.1 6.9e-47 157.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCH59896.1 - 2.1e-10 40.4 1.2 5.7e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCH59896.1 - 1.5e-07 31.4 0.0 5.9e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCH59896.1 - 5e-05 23.1 0.1 9.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCH59896.1 - 0.00021 21.7 0.2 0.00054 20.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain LIM_bind PF01803.11 CCH59896.1 - 2 7.4 4.8 0.63 9.1 0.2 2.1 1 1 1 2 2 2 0 LIM-domain binding protein EF1G PF00647.14 CCH59897.1 - 3.4e-47 158.5 0.1 6.9e-47 157.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCH59897.1 - 2e-12 46.9 0.1 2e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCH59897.1 - 2.2e-10 40.5 0.0 8.1e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCH59897.1 - 4.4e-07 30.3 0.1 1.2e-06 28.8 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCH59897.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCH59897.1 - 0.00031 20.8 0.0 0.00062 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LIM_bind PF01803.11 CCH59897.1 - 0.23 10.5 1.8 0.61 9.1 0.0 2.0 1 1 1 2 2 2 0 LIM-domain binding protein TUG-UBL1 PF11470.3 CCH59898.1 - 3.2e-12 46.1 12.6 5.5e-11 42.2 0.4 3.8 4 0 0 4 4 4 2 GLUT4 regulating protein TUG UBX PF00789.15 CCH59898.1 - 7.2e-12 45.2 0.2 3.7e-11 42.9 0.0 2.2 2 1 1 3 3 3 1 UBX domain UN_NPL4 PF11543.3 CCH59898.1 - 0.023 14.9 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-CHY PF05495.7 CCH59899.1 - 1.7e-16 60.1 14.6 2.5e-16 59.5 10.1 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 CCH59899.1 - 0.0043 17.0 10.8 5.6 7.0 7.5 3.1 1 1 0 1 1 1 1 zinc-finger Tmemb_55A PF09788.4 CCH59899.1 - 0.02 14.0 5.3 0.025 13.7 3.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A DZR PF12773.2 CCH59899.1 - 0.36 10.6 13.5 8.3 6.3 9.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 CCH59899.1 - 0.45 10.1 0.3 0.45 10.1 0.2 3.4 4 0 0 4 4 4 0 zinc-ribbon domain HypA PF01155.14 CCH59899.1 - 0.58 9.8 7.7 1.1 9.0 3.9 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CCH59899.1 - 3.3 7.7 8.8 0.51 10.3 0.9 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Cytochrome_C7 PF14522.1 CCH59899.1 - 4.1 7.1 16.3 13 5.5 10.8 2.2 1 1 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CCH59899.1 - 6.8 7.1 14.8 24 5.3 10.0 2.1 1 1 0 1 1 1 0 Cytochrome c3 DUF1451 PF07295.6 CCH59899.1 - 8.4 6.1 8.8 0.48 10.1 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Ldh_1_C PF02866.13 CCH59900.1 - 1e-45 155.5 0.0 1.4e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CCH59900.1 - 2.2e-44 150.7 0.0 3e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCH59900.1 - 0.00027 19.7 0.0 0.00037 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCH59900.1 - 0.045 14.0 0.0 0.77 10.0 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 CCH59900.1 - 0.43 9.8 1.9 1.9 7.7 0.3 2.4 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase G-alpha PF00503.15 CCH59901.1 - 7.2e-108 360.7 0.0 8.7e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCH59901.1 - 4.5e-14 52.0 0.2 3.6e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CCH59901.1 - 0.0043 17.5 0.0 4.7 7.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 CCH59901.1 - 0.041 13.0 0.1 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CCH59901.1 - 0.093 12.2 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyto_heme_lyase PF01265.12 CCH59902.1 - 3.4e-64 216.9 8.9 2.6e-63 214.0 6.1 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-Tim10_DDP PF02953.10 CCH59903.1 - 2.1e-23 81.3 2.6 2.5e-23 81.1 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CCH59903.1 - 0.0029 17.0 2.3 0.0036 16.7 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Flavoprotein PF02441.14 CCH59904.1 - 6.2e-41 139.0 0.6 1.5e-40 137.8 0.4 1.7 1 0 0 1 1 1 1 Flavoprotein DUF1939 PF09154.5 CCH59904.1 - 0.039 13.8 3.1 0.17 11.7 2.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) Ydc2-catalyt PF09159.5 CCH59906.1 - 4.8e-47 160.7 0.3 6.7e-47 160.2 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Peptidase_S24 PF00717.18 CCH59907.1 - 2.5e-09 36.6 0.1 3.9e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like FF PF01846.14 CCH59908.1 - 1.5e-32 111.3 17.8 4.2e-12 45.8 0.0 6.8 7 0 0 7 7 7 3 FF domain WW PF00397.21 CCH59908.1 - 6e-19 67.5 8.7 2.9e-09 36.6 0.4 2.8 2 0 0 2 2 2 2 WW domain Fungal_trans PF04082.13 CCH59909.1 - 2.4e-16 59.4 6.7 2.4e-16 59.4 4.6 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Mt_ATP-synt_D PF05873.7 CCH59910.1 - 8.9e-15 54.6 5.6 1.2e-14 54.3 3.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Arginosuc_synth PF00764.14 CCH59910.1 - 0.002 17.2 0.3 0.015 14.3 0.2 2.0 1 1 0 1 1 1 1 Arginosuccinate synthase DUF1537 PF07005.6 CCH59910.1 - 0.079 12.6 0.6 0.14 11.7 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF1537 Hom_end_hint PF05203.11 CCH59910.1 - 0.1 12.3 3.0 0.12 12.1 2.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint LTXXQ PF07813.7 CCH59910.1 - 0.93 9.9 7.8 2.7 8.4 0.4 2.2 1 1 1 2 2 2 0 LTXXQ motif family protein DUF2408 PF10303.4 CCH59910.1 - 1.5 8.9 6.6 19 5.3 4.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) TPR_MLP1_2 PF07926.7 CCH59910.1 - 9.4 5.9 12.4 5.9 6.6 3.2 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_12 PF13087.1 CCH59911.1 - 3.4e-59 199.5 2.5 4.2e-59 199.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 CCH59911.1 - 5.4e-52 176.7 1.7 1.1e-51 175.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH59911.1 - 1.9e-13 49.9 0.0 5.4e-13 48.5 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 CCH59911.1 - 1.6e-10 40.8 0.0 3.4e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CCH59911.1 - 1.4e-07 31.3 0.2 0.046 13.2 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CCH59911.1 - 8.3e-06 25.3 0.0 4.9e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CCH59911.1 - 2.6e-05 24.3 0.1 0.001 19.2 0.1 2.8 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 CCH59911.1 - 6.7e-05 22.5 0.0 0.00082 19.0 0.0 2.7 3 0 0 3 3 3 1 Helicase ResIII PF04851.10 CCH59911.1 - 9.4e-05 22.3 0.0 0.00061 19.6 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CCH59911.1 - 0.0001 21.3 0.2 0.032 13.2 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zot PF05707.7 CCH59911.1 - 0.00026 20.4 0.0 0.00071 19.1 0.0 1.8 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) PhoH PF02562.11 CCH59911.1 - 0.00032 19.9 0.1 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein TrwB_AAD_bind PF10412.4 CCH59911.1 - 0.00056 18.6 0.1 0.0024 16.5 0.0 2.1 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 CCH59911.1 - 0.00066 18.7 0.4 0.091 11.6 0.0 3.0 3 0 0 3 3 3 1 PIF1-like helicase IstB_IS21 PF01695.12 CCH59911.1 - 0.00087 18.7 0.0 0.0025 17.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.24 CCH59911.1 - 0.0016 18.5 0.5 0.021 15.0 0.2 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 CCH59911.1 - 0.0017 17.8 0.0 0.006 16.0 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.1 CCH59911.1 - 0.0034 17.2 0.1 0.13 12.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF853 PF05872.7 CCH59911.1 - 0.0037 15.6 0.0 0.0059 15.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_25 PF13481.1 CCH59911.1 - 0.0097 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH59911.1 - 0.013 15.4 0.0 0.046 13.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 CCH59911.1 - 0.013 14.4 0.1 0.025 13.5 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CCH59911.1 - 0.027 14.5 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain AAA_10 PF12846.2 CCH59911.1 - 0.029 13.7 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 CCH59911.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UvrD_C PF13361.1 CCH59911.1 - 0.044 13.2 9.1 0.32 10.3 0.0 3.2 3 1 1 4 4 4 0 UvrD-like helicase C-terminal domain ArgK PF03308.11 CCH59911.1 - 0.054 12.2 0.0 0.14 10.9 0.0 1.6 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 CCH59911.1 - 0.065 14.0 1.4 0.19 12.5 0.2 2.4 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.9 CCH59911.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Flavi_DEAD PF07652.9 CCH59911.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain GTP_EFTU_D2 PF03144.20 CCH59911.1 - 0.11 12.5 0.5 6 7.0 0.1 3.1 3 1 0 3 3 2 0 Elongation factor Tu domain 2 AAA_18 PF13238.1 CCH59911.1 - 0.75 10.1 9.9 2.6 8.3 1.5 3.9 3 1 0 3 3 2 0 AAA domain WD40 PF00400.27 CCH59912.1 - 8.3e-12 44.5 0.7 0.0086 15.9 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.4 CCH59912.1 - 0.027 13.5 0.0 0.085 11.9 0.0 2.0 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller DUF3312 PF11768.3 CCH59912.1 - 0.17 10.1 0.0 0.29 9.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1748 PF08520.5 CCH59913.1 - 5.7e-12 45.1 0.0 8.1e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 CCH59914.1 - 3.3e-33 112.3 1.8 2.2e-07 30.5 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CCH59914.1 - 1.4e-06 26.7 1.0 0.026 12.6 0.2 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCH59914.1 - 2.4e-06 26.5 3.5 0.22 10.2 0.3 3.8 1 1 3 4 4 4 3 Nup133 N terminal like BBS2_Mid PF14783.1 CCH59914.1 - 0.0014 18.3 2.3 4.1 7.2 0.0 4.3 3 2 2 5 5 5 3 Ciliary BBSome complex subunit 2, middle region AlaDh_PNT_N PF05222.10 CCH59915.1 - 8.9e-29 100.2 0.0 1.2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCH59915.1 - 8.6e-16 57.9 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPR_11 PF13414.1 CCH59916.1 - 9.4e-29 98.8 7.4 9.8e-08 31.5 0.0 6.7 6 0 0 6 6 6 5 TPR repeat TPR_1 PF00515.23 CCH59916.1 - 1.6e-28 97.0 15.8 1.7e-06 27.3 0.1 9.8 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCH59916.1 - 3.6e-26 88.9 4.1 0.00043 19.9 0.0 9.0 10 0 0 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 CCH59916.1 - 5.5e-22 77.6 9.0 7.1e-19 67.7 0.0 5.2 4 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCH59916.1 - 3.5e-16 58.8 10.2 7.3e-07 29.0 0.0 7.6 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCH59916.1 - 1.2e-14 54.3 0.9 0.0034 17.7 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCH59916.1 - 2.1e-12 45.8 3.7 0.14 12.0 0.0 7.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCH59916.1 - 2.9e-12 45.4 18.2 0.11 12.2 0.2 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCH59916.1 - 1.9e-10 40.4 0.0 0.32 11.7 0.0 6.9 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCH59916.1 - 6.8e-10 38.3 5.9 0.056 13.6 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59916.1 - 8.5e-10 39.0 0.0 3.9 8.2 0.1 6.8 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCH59916.1 - 3.2e-06 27.2 2.7 2.9 8.5 0.1 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCH59916.1 - 5.9e-06 26.0 0.0 0.12 12.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCH59916.1 - 3.8e-05 23.4 0.6 7 6.7 0.0 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCH59916.1 - 0.0017 18.1 6.4 6.1 6.7 0.2 5.4 5 1 1 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat ADK PF00406.17 CCH59918.1 - 9.3e-48 161.9 0.0 1.4e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CCH59918.1 - 2.1e-08 34.5 0.1 4.4e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH59918.1 - 1.9e-07 31.9 0.0 2.7e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCH59918.1 - 2.7e-07 30.1 0.5 0.0065 15.8 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 CCH59918.1 - 1.4e-05 24.9 0.0 0.00017 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCH59918.1 - 0.08 12.0 0.1 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 CCH59918.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MFS_1 PF07690.11 CCH59919.1 - 2.5e-11 42.9 45.2 5.9e-10 38.3 30.9 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Grp1_Fun34_YaaH PF01184.14 CCH59920.1 - 1e-87 292.8 18.1 1.2e-87 292.5 12.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 CCH59921.1 - 4.2e-93 310.4 18.9 4.9e-93 310.2 13.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family RNA_pol_Rpc34 PF05158.7 CCH59922.1 - 7.6e-100 334.2 5.3 8.5e-100 334.1 3.7 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 CCH59922.1 - 0.016 15.3 1.0 0.042 13.9 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator B-block_TFIIIC PF04182.7 CCH59922.1 - 0.018 14.8 0.9 0.096 12.5 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC OHA PF14418.1 CCH59922.1 - 0.037 13.5 0.1 0.094 12.2 0.1 1.6 1 0 0 1 1 1 0 OST-HTH Associated domain HAD PF12710.2 CCH59923.1 - 1.6e-09 38.2 0.2 2.5e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 CCH59924.1 - 8.8e-95 317.9 28.9 1.2e-94 317.4 20.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59924.1 - 1.5e-25 89.6 27.6 5.3e-22 78.0 13.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3439 PF11921.3 CCH59924.1 - 0.59 9.8 4.9 1.6 8.5 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sugar_tr PF00083.19 CCH59925.1 - 5.1e-95 318.6 32.3 6.8e-95 318.2 22.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH59925.1 - 1.2e-29 103.1 29.5 8.1e-27 93.8 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.4 CCH59926.1 - 5.4e-31 107.7 17.4 5.4e-31 107.7 12.0 3.8 4 1 0 4 4 4 1 Frag1/DRAM/Sfk1 family Zn_clus PF00172.13 CCH59927.1 - 1.9e-07 30.8 6.9 4.7e-07 29.6 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCH59927.1 - 1.1e-06 27.7 16.0 2.7e-05 23.1 8.7 3.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain ABC1 PF03109.11 CCH59928.1 - 7e-32 109.9 0.3 3e-31 107.8 0.0 2.1 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 CCH59928.1 - 3.8e-05 23.1 0.0 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Claudin_2 PF13903.1 CCH59929.1 - 0.0017 18.0 0.3 0.29 10.7 0.1 2.1 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction TP_methylase PF00590.15 CCH59930.1 - 3.2e-21 76.0 0.0 4.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CCH59930.1 - 0.05 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) MFS_1 PF07690.11 CCH59931.1 - 8.1e-31 106.9 49.1 8.1e-31 106.9 34.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH59931.1 - 0.00036 19.2 13.2 0.00036 19.2 9.2 3.1 2 2 0 2 2 2 1 Sugar (and other) transporter CAAD PF14159.1 CCH59931.1 - 0.28 10.8 6.9 28 4.4 0.1 4.4 3 1 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase WHIM1 PF15612.1 CCH59932.1 - 0.032 14.1 0.2 0.25 11.3 0.0 2.6 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 1 SNARE PF05739.14 CCH59933.1 - 8.4e-18 63.8 1.2 2.5e-17 62.3 0.8 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CCH59933.1 - 6.4e-06 26.2 0.1 6.4e-06 26.2 0.0 3.4 2 2 1 3 3 3 1 Syntaxin DUF1690 PF07956.6 CCH59934.1 - 2.2e-35 121.6 8.1 2.5e-35 121.5 5.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF2733 PF10813.3 CCH59934.1 - 0.011 15.2 0.0 0.029 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) CHCH PF06747.8 CCH59934.1 - 0.029 14.2 0.3 0.048 13.5 0.2 1.4 1 0 0 1 1 1 0 CHCH domain Pox_A_type_inc PF04508.7 CCH59934.1 - 0.074 12.8 4.1 3.5 7.6 0.1 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF1831 PF08866.5 CCH59934.1 - 0.13 12.5 1.8 0.12 12.6 0.5 1.5 2 0 0 2 2 2 0 Putative amino acid metabolism UCH PF00443.24 CCH59935.1 - 9.9e-54 182.2 1.9 1.4e-53 181.7 1.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH59935.1 - 2.1e-18 66.8 11.8 2.1e-18 66.8 8.2 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCH59935.1 - 3.3e-09 36.0 0.4 1.5e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 CCH59935.1 - 0.055 13.7 0.2 0.18 12.0 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain AA_permease PF00324.16 CCH59936.1 - 1.1e-116 390.0 43.8 1.4e-116 389.7 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH59936.1 - 1e-33 116.5 44.9 1.3e-33 116.2 31.1 1.1 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.22 CCH59937.1 - 1.1e-46 158.5 0.2 8.8e-23 81.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CCH59937.1 - 9.8e-21 73.4 8.8 9.8e-21 73.4 6.1 3.0 3 1 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 CCH59937.1 - 4.1e-16 59.7 19.1 1.3e-05 25.2 0.0 5.8 4 2 1 5 5 5 3 AAA domain SMC_N PF02463.14 CCH59937.1 - 1.6e-10 40.5 0.3 0.013 14.7 0.2 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCH59937.1 - 6.4e-09 36.6 6.1 0.00079 20.2 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.1 CCH59937.1 - 3.1e-07 30.5 1.1 0.017 15.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 CCH59937.1 - 5.3e-07 29.8 0.1 0.044 13.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain NACHT PF05729.7 CCH59937.1 - 8.9e-07 28.7 0.1 0.0057 16.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 CCH59937.1 - 9.7e-07 28.1 0.0 0.037 13.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCH59937.1 - 1e-06 28.1 0.1 0.067 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 CCH59937.1 - 3.2e-06 27.2 1.4 0.056 13.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CCH59937.1 - 3.3e-06 27.5 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 CCH59937.1 - 7.3e-06 25.7 0.0 0.054 13.1 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCH59937.1 - 1.2e-05 25.2 0.0 0.14 12.0 0.0 3.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCH59937.1 - 1.4e-05 24.9 0.0 0.15 12.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 CCH59937.1 - 1.6e-05 25.0 0.1 0.053 13.7 0.1 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCH59937.1 - 3.1e-05 23.8 0.0 0.085 12.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.20 CCH59937.1 - 4.1e-05 23.1 0.0 0.034 13.6 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 CCH59937.1 - 4.9e-05 22.5 24.1 0.2 10.6 0.0 6.0 2 1 3 6 6 5 3 AAA ATPase domain PduV-EutP PF10662.4 CCH59937.1 - 5.1e-05 22.7 1.5 0.1 12.1 0.1 3.4 4 0 0 4 4 3 2 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 CCH59937.1 - 0.00035 19.5 0.0 0.35 9.6 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.1 CCH59937.1 - 0.00037 20.8 28.6 0.33 11.2 0.0 5.2 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.17 CCH59937.1 - 0.00054 20.0 0.0 0.61 10.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 CCH59937.1 - 0.00075 19.3 0.0 2.1 8.2 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CCH59937.1 - 0.00079 18.9 0.8 1.8 7.9 0.1 3.1 3 1 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 CCH59937.1 - 0.0018 17.7 0.1 2.1 7.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain Pox_A32 PF04665.7 CCH59937.1 - 0.003 16.8 0.1 0.07 12.4 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_18 PF13238.1 CCH59937.1 - 0.0073 16.6 16.8 0.2 11.9 0.3 5.0 5 2 0 5 5 4 2 AAA domain ArgK PF03308.11 CCH59937.1 - 0.0074 15.0 0.0 0.56 8.9 0.0 2.6 2 0 0 2 2 2 1 ArgK protein AAA_5 PF07728.9 CCH59937.1 - 0.0094 15.6 2.2 3.8 7.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CCH59937.1 - 0.0095 15.6 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 1 NTPase cobW PF02492.14 CCH59937.1 - 0.0096 15.3 0.1 1.8 8.0 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CCH59937.1 - 0.016 14.1 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 CCH59937.1 - 0.019 14.2 0.1 3.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.17 CCH59937.1 - 0.023 14.1 0.1 1.2 8.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 CCH59937.1 - 0.027 13.9 0.6 2 7.8 0.0 3.0 2 1 1 3 3 3 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 CCH59937.1 - 0.032 13.9 0.0 0.032 13.9 0.0 3.5 4 1 0 4 4 3 0 Archaeal ATPase UPF0079 PF02367.12 CCH59937.1 - 0.086 12.4 0.2 0.89 9.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 CCH59937.1 - 1.1 8.9 0.0 1.1 8.9 0.0 4.8 4 1 1 5 5 5 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 CCH59937.1 - 2.6 7.8 15.3 0.18 11.6 0.1 4.2 3 2 1 4 4 4 0 Dynamin family AA_permease PF00324.16 CCH59939.1 - 1e-128 429.7 31.9 1.2e-128 429.5 22.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH59939.1 - 6.2e-27 94.1 36.8 8e-27 93.8 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.7 CCH59939.1 - 1 9.3 7.5 0.7 9.8 0.7 3.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF485 PF04341.7 CCH59939.1 - 1.4 8.6 0.0 1.4 8.6 0.0 4.5 4 1 1 5 5 5 0 Protein of unknown function, DUF485 Aminotran_5 PF00266.14 CCH59940.1 - 3.7e-99 331.9 0.0 4.5e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCH59940.1 - 8.8e-09 34.9 0.0 1.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCH59940.1 - 2e-08 33.6 0.5 8.4e-08 31.6 0.0 2.1 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CCH59940.1 - 2.3e-07 30.0 0.0 4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 CCH59940.1 - 0.0016 16.9 0.0 0.0025 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DnaB_bind PF10410.4 CCH59940.1 - 0.05 13.6 0.2 0.71 9.9 0.0 2.8 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase Mito_carr PF00153.22 CCH59941.1 - 1.6e-49 165.5 10.6 6.7e-17 60.9 0.2 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein DUF2036 PF09724.4 CCH59942.1 - 2.1e-68 230.8 2.4 2.6e-68 230.5 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DUF3507 PF12015.3 CCH59943.1 - 1.4e-37 128.9 2.4 1.4e-37 128.9 1.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3507) Iso_dh PF00180.15 CCH59944.1 - 1.3e-66 224.9 0.0 1.5e-66 224.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Flavodoxin_2 PF02525.12 CCH59945.1 - 5e-54 182.8 0.1 6.1e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCH59945.1 - 2.7e-14 52.9 0.0 3.9e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCH59945.1 - 0.0014 17.9 1.6 0.0033 16.8 1.1 1.8 1 1 0 1 1 1 1 Flavodoxin UPF0052 PF01933.13 CCH59946.1 - 2e-67 227.6 0.0 6.3e-67 226.0 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 Pkinase PF00069.20 CCH59947.1 - 1.5e-61 207.8 0.1 4.7e-61 206.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59947.1 - 1.9e-21 76.2 0.0 3.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59947.1 - 7.4e-10 38.2 0.0 1.8e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH59947.1 - 0.001 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CCH59947.1 - 0.026 13.8 0.1 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCH59947.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNF2_N PF00176.18 CCH59948.1 - 5e-53 179.8 0.2 1.2e-52 178.6 0.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CCH59948.1 - 1.4e-09 37.6 7.0 2.8e-09 36.6 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCH59948.1 - 2.3e-09 36.7 9.8 4.9e-09 35.7 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH59948.1 - 2e-07 30.9 10.5 4.7e-07 29.7 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH59948.1 - 1.5e-06 27.7 5.4 1.5e-06 27.7 3.8 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH59948.1 - 3e-06 26.8 7.7 6.4e-06 25.8 5.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCH59948.1 - 0.00022 21.0 9.1 0.00042 20.1 6.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Helicase_C PF00271.26 CCH59948.1 - 0.00045 20.0 0.4 0.0043 16.8 0.0 2.9 3 0 0 3 3 2 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.2 CCH59948.1 - 0.00057 19.9 4.4 0.0016 18.4 3.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCH59948.1 - 0.0012 18.5 6.6 0.0047 16.6 4.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CCH59948.1 - 0.004 16.9 2.1 0.0088 15.8 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CCH59948.1 - 0.011 15.2 3.5 0.033 13.7 2.4 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CCH59948.1 - 0.29 10.7 2.4 0.74 9.3 1.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CCH59948.1 - 3.3 7.3 8.0 6.9 6.3 5.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ion_trans PF00520.26 CCH59949.1 - 0.61 9.3 27.2 1.5e+04 -7.3 18.9 3.6 1 1 0 1 1 1 0 Ion transport protein Methyltransf_31 PF13847.1 CCH59950.1 - 1.6e-11 43.9 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH59950.1 - 2.3e-10 40.8 0.0 3.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH59950.1 - 3e-09 37.4 0.0 5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH59950.1 - 1.4e-08 35.1 0.1 3.1e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH59950.1 - 1.5e-07 31.6 0.1 3.5e-07 30.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH59950.1 - 1.8e-07 30.5 0.2 3.2e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CCH59950.1 - 1.8e-07 30.3 0.0 4.9e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCH59950.1 - 9.3e-07 28.7 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH59950.1 - 7.5e-05 22.1 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 CCH59950.1 - 0.00017 20.7 0.1 0.00025 20.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CCH59950.1 - 0.00036 20.5 0.0 0.00083 19.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCH59950.1 - 0.002 17.3 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 CCH59950.1 - 0.01 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 CCH59950.1 - 0.012 14.9 0.2 0.071 12.4 0.0 2.0 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.5 CCH59950.1 - 0.04 13.4 0.2 0.072 12.6 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 CCH59951.1 - 1.3e-09 37.8 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH59951.1 - 3.6e-09 36.9 0.0 9.3e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH59951.1 - 1.1e-08 35.3 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH59951.1 - 5.9e-08 32.9 0.0 1.2e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH59951.1 - 2.5e-07 31.2 0.0 5.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH59951.1 - 3.6e-05 23.0 0.0 7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 CCH59951.1 - 5.4e-05 22.9 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCH59951.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 CCH59951.1 - 0.014 14.4 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase tRNA_U5-meth_tr PF05958.6 CCH59951.1 - 0.019 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.8 CCH59951.1 - 0.033 13.2 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Oxidored_FMN PF00724.15 CCH59952.1 - 1.5e-121 405.6 0.0 1.7e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Alpha-amylase_C PF02806.13 CCH59953.1 - 1.3e-24 86.0 0.0 5.5e-24 84.1 0.0 2.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CCH59953.1 - 1.3e-17 64.2 0.2 1.3e-17 64.2 0.1 3.3 3 1 1 4 4 4 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CCH59953.1 - 5.4e-13 48.7 0.1 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Aminotran_5 PF00266.14 CCH59953.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Rota_NSP3 PF01665.11 CCH59953.1 - 0.17 10.8 0.1 0.3 10.0 0.1 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 RabGAP-TBC PF00566.13 CCH59955.1 - 1.5e-16 60.5 2.1 2.5e-16 59.8 1.5 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 CCH59956.1 - 4.6e-05 22.9 0.2 0.0079 15.8 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH59956.1 - 0.00047 19.9 1.5 0.0015 18.3 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH59956.1 - 0.0014 18.5 0.0 0.092 12.7 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 CCH59956.1 - 0.09 12.0 0.1 0.58 9.4 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated HSP70 PF00012.15 CCH59957.1 - 5.6e-33 113.7 10.0 5.6e-33 113.7 6.9 2.7 2 1 0 2 2 2 1 Hsp70 protein DUF4482 PF14818.1 CCH59957.1 - 0.7 10.5 16.2 0.026 15.1 2.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) DUF1115 PF06544.7 CCH59957.1 - 2.4 7.8 6.3 0.29 10.8 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1115) V_ATPase_I PF01496.14 CCH59958.1 - 7.6e-277 920.1 5.2 8.7e-277 919.9 3.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Lzipper-MIP1 PF14389.1 CCH59958.1 - 0.27 11.3 2.3 0.25 11.4 0.1 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF948 PF06103.6 CCH59958.1 - 1.9 8.3 4.4 4.5 7.1 0.1 3.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) HC2 PF07382.6 CCH59959.1 - 0.43 10.4 12.6 0.71 9.7 8.7 1.5 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 ATP_synt_H PF05493.8 CCH59960.1 - 2.4e-22 78.7 3.5 2.7e-22 78.5 2.4 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Git3 PF11710.3 CCH59960.1 - 0.0018 17.8 0.7 0.0018 17.8 0.5 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 MgtE PF01769.11 CCH59960.1 - 0.0053 17.0 0.7 0.0055 16.9 0.5 1.0 1 0 0 1 1 1 1 Divalent cation transporter DUF3624 PF12292.3 CCH59960.1 - 0.011 16.0 1.9 0.018 15.4 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) UPF0104 PF03706.8 CCH59960.1 - 0.031 13.5 1.7 0.034 13.4 1.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Glucos_trans_II PF14264.1 CCH59960.1 - 0.044 12.7 1.5 0.044 12.7 1.0 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF2079 PF09852.4 CCH59960.1 - 0.082 11.6 3.0 0.086 11.5 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF3290 PF11694.3 CCH59960.1 - 0.18 11.5 0.9 0.2 11.3 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF4131 PF13567.1 CCH59960.1 - 0.21 10.9 2.8 0.22 10.8 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Rab5ip PF07019.7 CCH59960.1 - 2 8.6 4.8 2.9 8.0 3.4 1.3 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) UEV PF05743.8 CCH59961.1 - 1.5e-28 98.9 0.1 3.1e-28 97.9 0.1 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 CCH59961.1 - 1.3e-21 75.9 1.0 8.4e-21 73.3 0.9 2.2 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.21 CCH59961.1 - 3.6e-05 23.2 0.3 3.6e-05 23.2 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH59961.1 - 0.15 11.7 1.6 0.99 9.1 0.0 2.9 3 0 0 3 3 3 0 Prokaryotic E2 family B TetR_C_8 PF14278.1 CCH59961.1 - 1.1 9.6 7.2 8.5 6.8 0.4 3.8 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region DKCLD PF08068.7 CCH59962.1 - 1.1e-29 102.0 0.2 4.9e-29 100.0 0.1 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CCH59962.1 - 2.2e-20 73.3 11.1 7.1e-20 71.6 0.0 4.1 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CCH59962.1 - 1.3e-19 69.6 1.1 2.6e-19 68.7 0.8 1.5 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 CCH59962.1 - 0.21 11.4 21.1 0.3 11.0 14.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Adeno_VII PF03228.9 CCH59962.1 - 0.84 10.2 10.6 1.7 9.2 7.4 1.6 1 0 0 1 1 1 0 Adenoviral core protein VII FLO_LFY PF01698.11 CCH59962.1 - 7.3 5.3 23.5 9.7 4.9 16.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DnaJ PF00226.26 CCH59963.1 - 5.8e-24 83.5 0.3 1.2e-23 82.5 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCH59963.1 - 4.6e-23 80.9 0.7 4.8e-19 68.0 0.0 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain RFX_DNA_binding PF02257.10 CCH59964.1 - 1e-32 112.0 0.0 2.3e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain DUF3571 PF12095.3 CCH59964.1 - 0.21 11.8 1.7 3.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) RAP1 PF07218.6 CCH59964.1 - 0.71 7.9 11.5 1.4 6.9 8.0 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2807 PF10988.3 CCH59964.1 - 6 6.3 9.5 9.8 5.6 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) Iso_dh PF00180.15 CCH59965.1 - 1.1e-129 432.4 0.0 1.2e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L30 PF00327.15 CCH59966.1 - 4.8e-12 45.2 0.7 1.2e-11 44.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_viral_C PF00336.13 CCH59966.1 - 0.0034 16.6 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase (viral) C-terminal domain PDCD2_C PF04194.8 CCH59967.1 - 2.5e-37 128.0 6.5 2.8e-35 121.3 0.0 3.4 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain DUF2296 PF10058.4 CCH59967.1 - 0.0024 17.6 0.2 3 7.6 0.0 2.6 2 0 0 2 2 2 2 Predicted integral membrane metal-binding protein (DUF2296) Flag1_repress PF03614.8 CCH59967.1 - 0.067 12.7 0.2 0.2 11.2 0.1 1.8 1 0 0 1 1 1 0 Repressor of phase-1 flagellin GTP_EFTU PF00009.22 CCH59968.1 - 1.1e-31 109.7 1.4 2.5e-31 108.5 1.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCH59968.1 - 7.4e-25 86.9 1.1 7.4e-25 86.9 0.8 2.3 2 0 0 2 2 2 1 Translation-initiation factor 2 Miro PF08477.8 CCH59968.1 - 3.4e-08 34.0 0.9 8e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CCH59968.1 - 3.5e-07 29.6 1.0 8.5e-07 28.3 0.7 1.7 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCH59968.1 - 5.7e-07 29.0 1.2 1.6e-06 27.6 0.1 2.2 2 1 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 CCH59968.1 - 7e-07 29.2 1.8 7e-07 29.2 1.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCH59968.1 - 2.3e-05 23.6 1.0 2.3e-05 23.6 0.7 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CCH59968.1 - 0.00082 19.2 6.5 0.024 14.4 1.0 3.2 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 CCH59968.1 - 0.012 15.9 1.4 0.092 13.0 0.1 2.7 2 0 0 2 2 2 0 ABC transporter UPF0728 PF15092.1 CCH59968.1 - 0.057 13.3 0.1 0.28 11.0 0.1 2.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 AAA_14 PF13173.1 CCH59968.1 - 0.092 12.6 3.6 0.33 10.8 0.1 2.8 2 1 0 2 2 2 0 AAA domain MRC1 PF09444.5 CCH59968.1 - 1.1 9.6 5.9 0.22 11.8 0.5 2.3 2 0 0 2 2 2 0 MRC1-like domain Mito_fiss_reg PF05308.6 CCH59969.1 - 0.052 12.9 2.9 0.059 12.7 2.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TPP_enzyme_N PF02776.13 CCH59970.1 - 1.4e-26 92.9 0.0 2.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCH59970.1 - 1e-21 77.1 0.1 3e-21 75.5 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCH59970.1 - 1.1e-20 73.7 0.0 2e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pet191_N PF10203.4 CCH59971.1 - 1.3e-24 86.0 3.3 1.7e-24 85.6 2.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CCH59971.1 - 0.013 15.2 0.5 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CCH59971.1 - 0.29 11.0 2.8 2.6 8.0 0.6 2.5 2 1 0 2 2 2 0 CHCH domain Rav1p_C PF12234.3 CCH59972.1 - 1.3e-247 823.0 5.0 1.3e-247 823.0 3.4 2.2 3 0 0 3 3 3 1 RAVE protein 1 C terminal WD40 PF00400.27 CCH59972.1 - 7.6e-08 31.9 1.4 0.36 10.8 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat AreA_N PF07573.6 CCH59972.1 - 7.2 7.2 6.3 18 5.9 0.6 2.6 1 1 1 2 2 2 0 Nitrogen regulatory protein AreA N terminus Pro_isomerase PF00160.16 CCH59973.1 - 1.2e-42 145.7 0.1 2.4e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCH59973.1 - 2.9e-12 46.0 5.4 2.7e-06 26.9 0.5 2.7 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCH59973.1 - 1.2e-08 34.1 14.6 2.3e-06 26.9 2.9 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCH59973.1 - 1.2e-08 34.1 8.1 0.00012 21.7 1.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCH59973.1 - 7.8e-06 25.7 1.0 0.00033 20.5 0.5 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCH59973.1 - 0.00036 21.1 0.2 0.001 19.6 0.0 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat Phage_term_smal PF05944.7 CCH59973.1 - 0.0019 17.8 0.0 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Phage small terminase subunit TPR_8 PF13181.1 CCH59973.1 - 0.019 14.7 2.5 0.019 14.7 1.7 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CCH59973.1 - 0.02 15.0 7.3 0.16 12.0 4.6 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCH59973.1 - 0.026 14.9 5.2 0.14 12.6 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCH59973.1 - 0.028 14.7 0.3 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Peripla_BP_4 PF13407.1 CCH59973.1 - 0.12 11.7 0.1 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF357 PF04010.8 CCH59973.1 - 5.4 6.7 6.3 2.7 7.7 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF357) Sec7 PF01369.15 CCH59974.1 - 3.7e-58 196.3 4.9 3.7e-58 196.3 3.4 2.9 3 0 0 3 3 3 1 Sec7 domain OMPdecase PF00215.19 CCH59975.1 - 8.3e-74 247.7 0.0 9.6e-74 247.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2235 PF09994.4 CCH59976.1 - 4.3e-80 269.0 0.0 5.8e-80 268.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) FSH1 PF03959.8 CCH59976.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HECT PF00632.20 CCH59977.1 - 6.6e-80 268.6 1.8 6.6e-80 268.6 1.2 3.2 4 0 0 4 4 4 1 HECT-domain (ubiquitin-transferase) Voltage_CLC PF00654.15 CCH59978.1 - 1.7e-80 270.7 25.1 1.7e-80 270.7 17.4 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CCH59978.1 - 1.8e-09 37.1 0.0 0.00055 19.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF4536 PF15055.1 CCH59978.1 - 0.12 12.5 5.3 0.07 13.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Urb2 PF10441.4 CCH59979.1 - 1.5e-27 96.6 3.3 5.9e-27 94.7 2.3 2.1 1 0 0 1 1 1 1 Urb2/Npa2 family Nucleopor_Nup85 PF07575.8 CCH59980.1 - 8.1e-133 443.6 11.9 1.4e-132 442.8 8.2 1.3 1 1 0 1 1 1 1 Nup85 Nucleoporin ATP-synt_C PF00137.16 CCH59981.1 - 3.4e-32 110.1 28.0 1.3e-18 66.6 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CDC27 PF09507.5 CCH59982.1 - 5.8e-06 25.8 39.6 0.0094 15.2 26.9 2.2 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 DUF106 PF01956.11 CCH59982.1 - 0.061 12.8 3.1 0.11 12.0 2.2 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 Phos_pyr_kin PF08543.7 CCH59983.1 - 1.5e-06 27.6 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CCH59983.1 - 9.1e-05 21.7 0.6 0.00045 19.4 0.1 2.4 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Vps55 PF04133.9 CCH59984.1 - 5.9e-41 138.9 4.7 7.1e-41 138.7 3.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2085 PF09858.4 CCH59984.1 - 0.03 14.3 0.1 0.03 14.3 0.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) SdpI PF13630.1 CCH59984.1 - 1.5 8.5 6.5 1.9 8.2 0.1 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family CDT1 PF08839.6 CCH59985.1 - 0.0029 17.5 3.7 0.0094 15.9 2.6 2.1 1 1 0 1 1 1 1 DNA replication factor CDT1 like DUF1691 PF07950.6 CCH59986.1 - 2.7e-11 43.3 2.4 1.6e-05 24.7 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) Apis_Csd PF11671.3 CCH59986.1 - 0.13 12.0 0.4 0.23 11.2 0.3 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Sdh_cyt PF01127.17 CCH59986.1 - 0.23 11.3 15.2 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PHD PF00628.24 CCH59987.1 - 5.2e-11 42.0 7.9 5.2e-11 42.0 5.5 2.6 2 0 0 2 2 2 1 PHD-finger UAE_UbL PF14732.1 CCH59987.1 - 0.036 14.1 1.3 3.6 7.7 0.0 2.7 2 1 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain WD40 PF00400.27 CCH59988.1 - 0.0041 16.9 2.5 8.5 6.4 0.1 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCH59988.1 - 0.041 13.7 1.9 0.13 12.2 0.5 2.5 2 1 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 CCH59989.1 - 6.7e-64 215.5 0.0 1.1e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH59989.1 - 7.2e-35 120.3 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH59989.1 - 4.5e-06 25.8 0.0 7.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH59989.1 - 0.016 14.2 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCH59989.1 - 0.02 14.2 0.1 0.045 13.0 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CCH59989.1 - 0.025 14.3 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Oxysterol_BP PF01237.13 CCH59990.1 - 3.7e-91 305.2 2.2 4.7e-91 304.9 1.6 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.6 CCH59991.1 - 2.7e-84 283.4 65.4 4.3e-84 282.7 45.4 1.3 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ABC_membrane_2 PF06472.10 CCH59992.1 - 4.6e-77 258.9 15.2 9.4e-77 257.8 10.5 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCH59992.1 - 2e-11 44.3 0.0 7.9e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 ABC transporter Methyltransf_23 PF13489.1 CCH59993.1 - 1.7e-16 60.3 0.0 3.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH59993.1 - 9.5e-15 54.8 1.0 1.7e-13 50.8 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH59993.1 - 1.5e-08 34.9 0.0 4.3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH59993.1 - 1.6e-08 34.8 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH59993.1 - 3.5e-07 29.9 0.0 9.2e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH59993.1 - 3.7e-06 27.4 0.0 1.6e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH59993.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCH59993.1 - 0.0041 17.1 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 CCH59993.1 - 0.055 12.1 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) APG5 PF04106.7 CCH59994.1 - 5.4e-43 146.7 1.6 6.7e-43 146.4 1.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 RRM_5 PF13893.1 CCH59995.1 - 0.016 15.0 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH59995.1 - 0.022 14.4 0.1 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 CCH59996.1 - 1.1e-64 218.5 2.2 1.8e-61 207.9 0.2 3.9 2 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) WD40 PF00400.27 CCH59997.1 - 1.1e-47 158.2 19.7 1.5e-10 40.5 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCH59997.1 - 0.12 11.1 2.8 2.1 7.0 0.1 3.6 1 1 4 5 5 5 0 Nup133 N terminal like MOZ_SAS PF01853.13 CCH59998.1 - 1.6e-89 298.1 1.4 2.2e-89 297.6 1.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CCH59998.1 - 5e-22 77.3 0.1 1.1e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CCH59998.1 - 0.017 15.1 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PTPA PF03095.10 CCH59999.1 - 1.2e-112 376.0 2.0 1.3e-112 375.8 1.4 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Beta-TrCP_D PF12125.3 CCH59999.1 - 0.049 13.2 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 D domain of beta-TrCP DAGAT PF03982.8 CCH60000.1 - 1.8e-74 250.1 4.1 9.7e-73 244.4 2.9 2.0 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Kinesin PF00225.18 CCH60001.1 - 7e-79 264.9 0.1 9.5e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain PAX PF00292.13 CCH60001.1 - 0.066 12.9 0.0 0.58 9.8 0.0 2.4 2 0 0 2 2 2 0 'Paired box' domain Ndc1_Nup PF09531.5 CCH60002.1 - 1.3e-80 271.6 14.7 2e-80 270.9 10.2 1.3 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.10 CCH60003.1 - 1.7e-53 180.4 0.0 2.7e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MSC PF09402.5 CCH60004.1 - 7.4e-90 301.0 8.7 7.4e-90 301.0 6.0 2.8 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCH60004.1 - 7.4e-08 31.8 0.4 1.7e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 HeH/LEM domain Zn_clus PF00172.13 CCH60004.1 - 1e-07 31.7 11.5 1e-07 31.7 8.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A_deaminase PF00962.17 CCH60005.1 - 7.4e-117 389.9 0.1 1e-116 389.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MAT1 PF06391.8 CCH60006.1 - 1.4e-54 184.7 33.1 1.8e-54 184.4 22.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 CCH60006.1 - 0.0024 17.4 5.6 0.0043 16.6 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH60006.1 - 0.0053 16.7 7.3 0.018 15.0 5.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH60006.1 - 0.0076 16.0 5.4 0.021 14.6 3.9 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCH60006.1 - 0.014 14.9 6.8 0.062 12.9 4.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH60006.1 - 0.081 12.6 9.0 0.46 10.2 6.3 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-piccolo PF05715.8 CCH60006.1 - 0.15 12.0 1.5 0.35 10.8 1.0 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_UBOX PF13445.1 CCH60006.1 - 0.51 10.1 5.0 1.5 8.6 3.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CCH60006.1 - 0.83 9.2 9.7 10 5.7 6.8 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain AP-5_subunit_s1 PF15001.1 CCH60006.1 - 5.5 6.8 8.6 0.72 9.7 0.9 2.2 1 1 1 2 2 2 0 AP-5 complex subunit sigma-1 CGI-121 PF08617.5 CCH60007.1 - 4.3e-29 101.2 7.3 5.4e-29 100.9 5.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Orthopox_B11R PF07033.6 CCH60007.1 - 9.1 5.8 11.5 3.2 7.2 3.0 2.6 3 1 0 3 3 3 0 Orthopoxvirus B11R protein MRP-L28 PF09812.4 CCH60009.1 - 5.7e-22 78.2 1.8 6.6e-22 78.0 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 SynMuv_product PF06047.6 CCH60009.1 - 0.15 11.8 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Ras-induced vulval development antagonist TPT PF03151.11 CCH60010.1 - 4.7e-33 114.0 7.4 4.7e-33 114.0 5.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CCH60010.1 - 3.1e-12 46.0 19.5 3.1e-10 39.4 7.1 2.1 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 CCH60010.1 - 1.6e-08 33.9 3.3 3.4e-05 23.0 0.8 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 CCH60010.1 - 0.045 13.8 28.9 0.035 14.1 4.8 2.8 3 0 0 3 3 3 0 EamA-like transporter family Ni_hydr_CYTB PF01292.15 CCH60010.1 - 0.098 12.0 0.1 0.098 12.0 0.1 2.8 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 zf-H2C2_2 PF13465.1 CCH60012.1 - 2.5e-08 33.8 4.7 2.5e-08 33.8 3.3 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCH60012.1 - 7.8e-08 32.2 12.9 0.00038 20.6 0.9 2.9 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH60012.1 - 3.7e-07 30.0 9.1 0.005 17.0 0.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCH60012.1 - 0.00042 20.4 1.9 0.081 13.1 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCH60012.1 - 0.0029 17.6 2.8 0.013 15.6 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCH60012.1 - 0.012 15.5 2.9 0.14 12.1 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Menin PF05053.8 CCH60012.1 - 0.029 12.5 1.5 0.043 12.0 1.0 1.2 1 0 0 1 1 1 0 Menin Ogr_Delta PF04606.7 CCH60012.1 - 0.17 11.5 3.4 0.21 11.2 0.1 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-BED PF02892.10 CCH60012.1 - 0.19 11.5 6.2 0.59 9.9 4.3 1.9 1 0 0 1 1 1 0 BED zinc finger zf-LYAR PF08790.6 CCH60012.1 - 0.23 11.1 3.4 0.12 12.0 0.9 1.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger MUG2_C PF08593.5 CCH60012.1 - 5.8 7.2 7.9 1.4 9.1 0.5 3.1 2 1 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal adh_short_C2 PF13561.1 CCH60013.1 - 4e-20 72.6 0.1 3.8e-19 69.4 0.0 2.6 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 CCH60013.1 - 4.5e-19 68.9 0.0 1e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CCH60013.1 - 2.8e-14 52.8 0.0 6.1e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CCH60013.1 - 3.2e-12 46.3 0.0 7.6e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 CCH60013.1 - 8.2e-06 25.8 0.0 3.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase SNARE PF05739.14 CCH60014.1 - 5.4e-14 51.6 8.8 5.4e-14 51.6 6.1 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CCH60014.1 - 4.2e-09 36.4 19.8 2.3e-08 34.1 3.9 2.5 2 0 0 2 2 2 2 Syntaxin Synaptobrevin PF00957.16 CCH60014.1 - 0.00049 19.6 3.2 0.00049 19.6 2.2 2.3 2 1 0 2 2 2 1 Synaptobrevin T2SF PF00482.18 CCH60014.1 - 0.006 16.4 0.4 0.015 15.2 0.3 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F MMPL PF03176.10 CCH60014.1 - 0.031 13.0 1.6 0.045 12.4 1.1 1.3 1 0 0 1 1 1 0 MMPL family BLOC1_2 PF10046.4 CCH60014.1 - 0.059 13.5 14.8 0.067 13.3 1.2 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3708 PF12501.3 CCH60014.1 - 0.34 10.7 6.4 1.1 9.0 2.1 2.3 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF848 PF05852.6 CCH60014.1 - 0.54 10.0 15.8 2.1 8.1 3.3 2.3 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2203 PF09969.4 CCH60014.1 - 4.1 7.6 10.9 2.3 8.4 2.0 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 CCH60014.1 - 4.4 7.1 8.7 0.91 9.3 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 CCH60014.1 - 4.9 6.6 17.0 0.54 9.7 7.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4094 PF13334.1 CCH60014.1 - 9.1 6.7 9.8 0.23 11.8 0.2 3.2 1 1 2 4 4 4 0 Domain of unknown function (DUF4094) ISG65-75 PF11727.3 CCH60014.1 - 9.9 5.1 15.6 0.56 9.2 4.0 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein EF-hand_7 PF13499.1 CCH60015.1 - 0.061 13.4 0.2 11 6.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair TFIIE_beta PF02186.10 CCH60016.1 - 3.1e-20 71.9 2.5 7.6e-20 70.6 1.7 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain PPP4R2 PF09184.6 CCH60016.1 - 0.019 14.5 24.6 0.034 13.6 17.1 1.3 1 0 0 1 1 1 0 PPP4R2 Daxx PF03344.10 CCH60016.1 - 0.046 12.2 17.0 0.066 11.6 11.8 1.2 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CCH60016.1 - 0.075 12.4 16.4 0.009 15.4 8.6 1.6 2 0 0 2 2 2 0 Spore coat protein CotO RNA_pol_3_Rpc31 PF11705.3 CCH60016.1 - 0.1 12.4 16.5 0.28 11.1 11.4 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 CCH60016.1 - 0.38 9.9 10.3 0.67 9.1 7.2 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 CCH60016.1 - 0.58 9.6 16.3 1.1 8.7 10.0 2.1 2 0 0 2 2 2 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CCH60016.1 - 1.5 9.1 13.9 3 8.1 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.7 CCH60016.1 - 2.7 7.1 7.4 4.4 6.4 5.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Prothymosin PF03247.9 CCH60016.1 - 3.5 7.8 29.9 0.16 12.0 15.0 2.7 3 0 0 3 3 3 0 Prothymosin/parathymosin family Senescence_reg PF04520.8 CCH60016.1 - 3.7 8.0 11.8 7.9 6.9 8.2 1.6 1 0 0 1 1 1 0 Senescence regulator DDRGK PF09756.4 CCH60016.1 - 3.7 6.8 21.8 0.12 11.7 10.8 1.7 2 0 0 2 2 2 0 DDRGK domain Presenilin PF01080.12 CCH60016.1 - 6.2 5.5 12.4 9.1 4.9 8.6 1.2 1 0 0 1 1 1 0 Presenilin Las1 PF04031.8 CCH60017.1 - 3.2e-50 169.7 0.6 8.1e-50 168.4 0.1 1.9 2 0 0 2 2 2 1 Las1-like Zn_clus PF00172.13 CCH60018.1 - 1.1e-08 34.7 9.9 2.2e-08 33.8 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VirE1 PF12189.3 CCH60018.1 - 0.2 11.7 1.7 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Single-strand DNA-binding protein NAD_binding_5 PF07994.7 CCH60019.1 - 1.9e-108 362.4 0.8 2.2e-108 362.2 0.5 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CCH60019.1 - 4.2e-45 152.1 0.2 1.1e-44 150.8 0.1 1.8 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF3927 PF13064.1 CCH60019.1 - 0.027 13.9 0.3 0.059 12.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) Vps39_1 PF10366.4 CCH60020.1 - 1.6e-24 86.0 3.8 1.6e-24 86.0 2.6 4.4 4 0 0 4 4 4 2 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CCH60020.1 - 9.4e-11 41.8 0.0 3.8e-10 39.9 0.0 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CENP-B_dimeris PF09026.5 CCH60020.1 - 0.39 10.9 16.1 0.54 10.5 2.0 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CCH60020.1 - 1.3 8.4 15.0 3.2 7.2 1.6 2.5 2 0 0 2 2 2 0 Nucleoplasmin AF1Q PF15017.1 CCH60020.1 - 7.9 6.4 11.8 10 6.0 0.5 2.7 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Utp21 PF04192.7 CCH60021.1 - 3.4e-81 271.8 0.1 6.1e-81 270.9 0.1 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CCH60021.1 - 6.3e-24 82.9 14.5 3.5e-08 33.0 0.2 9.1 9 0 0 9 9 9 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCH60021.1 - 0.00034 20.0 0.0 0.63 9.5 0.0 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 CCH60021.1 - 0.011 14.0 0.0 0.034 12.4 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.1 CCH60021.1 - 0.071 13.4 0.6 5.9 7.3 0.0 3.8 3 0 0 3 3 3 0 PQQ-like domain His_Phos_2 PF00328.17 CCH60022.1 - 3.5e-116 388.3 0.4 5.3e-116 387.7 0.3 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCH60022.1 - 1.1e-09 38.0 0.1 4e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCH60022.1 - 0.018 14.9 0.1 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Pribosyltran_N PF13793.1 CCH60023.1 - 3.6e-40 136.2 0.2 2.3e-39 133.7 0.0 2.4 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCH60023.1 - 1.4e-36 125.9 3.8 2.8e-33 115.1 2.6 2.2 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCH60023.1 - 1.1e-07 31.6 0.7 3.2e-06 26.8 0.3 2.5 2 1 0 2 2 2 1 Phosphoribosyl transferase domain SRR1 PF07985.7 CCH60024.1 - 4.6e-15 55.2 0.0 9.9e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 SRR1 Voldacs PF03517.8 CCH60025.1 - 2.2e-08 34.0 0.1 4e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling CIMR PF00878.13 CCH60027.1 - 4.5e-12 45.9 1.2 3.6e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 CCH60027.1 - 0.00015 21.3 0.1 0.0003 20.2 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.10 CCH60027.1 - 0.00027 20.0 0.2 0.0004 19.4 0.1 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor GTP_EFTU PF00009.22 CCH60028.1 - 2.5e-57 193.3 0.1 3.4e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCH60028.1 - 5e-35 119.6 0.0 1.2e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCH60028.1 - 2.9e-16 59.3 1.5 2.9e-16 59.3 1.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCH60028.1 - 9.1e-05 22.0 0.4 9.1e-05 22.0 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCH60028.1 - 0.00072 19.5 0.2 0.002 18.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_5 PF13893.1 CCH60029.1 - 7.3e-12 44.9 0.8 8.8e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH60029.1 - 4.7e-11 42.1 0.7 5.1e-06 26.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60029.1 - 1.4e-09 37.7 0.2 0.00013 21.8 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1874 PF08960.5 CCH60029.1 - 0.019 14.6 0.1 0.053 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) tRNA-synt_2b PF00587.20 CCH60030.1 - 2.3e-67 225.9 0.0 4.3e-67 225.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH60030.1 - 1e-21 76.6 0.3 1e-21 76.6 0.2 2.2 2 0 0 2 2 2 1 Anticodon binding domain DIM1 PF02966.11 CCH60031.1 - 1.4e-67 225.2 1.1 1.6e-67 225.1 0.8 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CCH60031.1 - 0.0085 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin RP1-2 PF12042.3 CCH60033.1 - 0.32 10.6 6.0 0.54 9.8 4.2 1.3 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain ATP-synt_ab PF00006.20 CCH60034.1 - 7.2e-61 205.4 0.0 9.9e-61 204.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCH60034.1 - 2.6e-18 66.5 1.0 5e-18 65.6 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCH60034.1 - 1.1e-13 51.1 0.9 2.3e-13 50.1 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCH60034.1 - 8.5e-05 22.3 0.5 0.00026 20.8 0.4 1.9 1 0 0 1 1 1 1 HAS barrel domain Atg14 PF10186.4 CCH60035.1 - 8.1e-23 80.8 18.4 8.1e-23 80.8 12.8 2.1 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 NOP5NT PF08156.8 CCH60035.1 - 0.6 10.3 3.7 0.38 10.9 0.3 2.5 2 1 0 2 2 2 0 NOP5NT (NUC127) domain COX5A PF02284.11 CCH60036.1 - 0.084 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Peptidase_C50 PF03568.12 CCH60037.1 - 7.2e-118 393.5 0.9 7.2e-118 393.5 0.6 3.4 3 0 0 3 3 3 1 Peptidase family C50 CHAT PF12770.2 CCH60037.1 - 0.069 12.2 0.0 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 CHAT domain PH PF00169.24 CCH60038.1 - 2.4e-09 37.3 0.1 2.4e-09 37.3 0.1 3.2 3 2 0 3 3 3 1 PH domain Mitofilin PF09731.4 CCH60038.1 - 0.043 12.4 0.1 0.043 12.4 0.1 2.5 3 0 0 3 3 3 0 Mitochondrial inner membrane protein Mito_carr PF00153.22 CCH60039.1 - 1.5e-58 194.4 1.3 1.7e-19 69.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_1 PF00133.17 CCH60040.1 - 5.8e-203 675.2 0.3 3.2e-202 672.7 0.2 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCH60040.1 - 1.8e-27 95.9 5.3 4e-27 94.8 3.7 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCH60040.1 - 6.5e-19 67.8 1.0 5.9e-09 35.0 0.0 5.0 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCH60040.1 - 2.9e-12 46.2 0.1 5.4e-08 32.3 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 CCH60040.1 - 0.016 14.0 1.2 12 4.5 0.1 3.5 2 1 0 3 3 3 0 tRNA synthetases class I (R) Val_tRNA-synt_C PF10458.4 CCH60040.1 - 0.017 15.2 2.0 0.034 14.2 0.4 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm RRM_1 PF00076.17 CCH60041.1 - 1.3e-68 226.5 13.6 8.8e-18 63.7 0.0 6.4 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60041.1 - 2.9e-62 206.5 5.0 9.4e-16 57.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60041.1 - 7.7e-38 128.1 0.7 1.1e-09 37.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCH60041.1 - 5.8e-06 25.9 0.1 0.097 12.4 0.0 4.3 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCH60041.1 - 0.0062 16.2 1.2 1.9 8.3 0.0 3.5 2 1 1 3 3 3 2 Limkain b1 Pkinase PF00069.20 CCH60042.1 - 2.7e-53 180.7 0.0 2.4e-52 177.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60042.1 - 2e-27 95.9 0.1 2.3e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCH60042.1 - 1.7e-06 28.4 1.9 4.5e-06 27.0 0.9 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCH60042.1 - 0.00094 18.2 0.0 0.018 14.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCH60042.1 - 0.016 14.2 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M15_3 PF08291.6 CCH60042.1 - 0.025 14.3 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase M15 APH PF01636.18 CCH60042.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.13 CCH60043.1 - 1.7e-38 131.2 0.1 4.8e-38 129.8 0.0 1.8 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 CCH60043.1 - 1.5e-30 106.1 3.3 1.5e-30 106.1 2.3 2.0 3 0 0 3 3 3 1 Prp31 C terminal domain NOSIC PF08060.8 CCH60043.1 - 9.2e-13 47.7 2.6 2.8e-12 46.2 0.3 2.6 2 0 0 2 2 2 1 NOSIC (NUC001) domain DUF1746 PF08508.5 CCH60044.1 - 1e-05 25.4 0.2 0.51 10.2 0.0 3.1 3 0 0 3 3 3 3 Fungal domain of unknown function (DUF1746) Borrelia_REV PF03978.8 CCH60044.1 - 0.13 11.9 1.3 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein DUF1664 PF07889.7 CCH60045.1 - 1.4 8.6 16.7 0.018 14.8 4.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RPN7 PF10602.4 CCH60046.1 - 4.1e-51 172.8 3.5 7e-51 172.1 2.4 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CCH60046.1 - 1.6e-16 60.5 2.2 1.7e-16 60.4 0.1 2.2 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CCH60046.1 - 0.0015 18.3 0.1 0.0038 17.0 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 BBS1 PF14779.1 CCH60046.1 - 0.0026 16.7 0.4 0.005 15.8 0.3 1.4 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 Interferon PF00143.14 CCH60046.1 - 0.0081 16.0 1.6 0.017 14.9 1.1 1.5 1 0 0 1 1 1 1 Interferon alpha/beta domain HTH_11 PF08279.7 CCH60046.1 - 0.041 13.5 0.1 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 HTH domain TPR_12 PF13424.1 CCH60046.1 - 0.086 12.7 0.8 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.19 CCH60047.1 - 9.5e-19 66.6 38.0 1.4e-05 24.6 0.6 5.8 6 1 0 6 6 6 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCH60047.1 - 0.00041 20.2 39.0 0.22 11.5 2.0 6.1 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Pil1 PF13805.1 CCH60048.1 - 2.2e-132 440.2 0.0 2.7e-132 439.9 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Baculo_VP39 PF04501.7 CCH60048.1 - 0.02 13.9 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Baculovirus major capsid protein VP39 DRY_EERY PF09750.4 CCH60048.1 - 2.3 8.3 8.7 19 5.4 2.6 2.5 2 0 0 2 2 2 0 Alternative splicing regulator Fork_head PF00250.13 CCH60049.1 - 2.3e-31 107.7 1.1 6.4e-31 106.2 0.7 1.8 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCH60049.1 - 3e-13 49.6 0.3 8.1e-13 48.2 0.2 1.8 1 0 0 1 1 1 1 FHA domain Ribosomal_L5_C PF00673.16 CCH60050.1 - 2.3e-23 81.7 0.1 3.5e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCH60050.1 - 4.2e-21 74.4 0.3 1e-20 73.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 BCAS2 PF05700.6 CCH60051.1 - 6.9e-05 22.4 5.8 6.9e-05 22.4 4.0 1.8 1 1 0 2 2 2 1 Breast carcinoma amplified sequence 2 (BCAS2) Runt PF00853.14 CCH60051.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Runt domain ALMT PF11744.3 CCH60051.1 - 0.18 10.3 2.6 0.21 10.2 1.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter IF-2B PF01008.12 CCH60053.1 - 2.4e-104 348.2 0.4 2.4e-104 348.2 0.3 1.8 2 0 0 2 2 2 1 Initiation factor 2 subunit family MAS20 PF02064.10 CCH60054.1 - 2.4e-17 62.9 0.4 1.8e-16 60.1 0.3 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor FIST_C PF10442.4 CCH60054.1 - 0.0061 16.5 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 FIST C domain SLX9 PF15341.1 CCH60055.1 - 5.7e-17 62.2 21.4 5.7e-17 62.2 14.9 2.2 2 1 0 2 2 2 1 Ribosome biogenesis protein SLX9 CorA PF01544.13 CCH60055.1 - 0.087 11.8 4.7 0.13 11.2 3.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AKAP95 PF04988.7 CCH60055.1 - 0.12 12.1 3.3 0.24 11.1 0.5 2.2 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Tweety PF04906.8 CCH60055.1 - 0.12 10.7 1.1 0.17 10.2 0.7 1.2 1 0 0 1 1 1 0 Tweety DUF940 PF06082.6 CCH60055.1 - 0.83 8.1 4.9 0.88 8.0 3.4 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Endonuc_Holl PF10107.4 CCH60055.1 - 2.8 7.6 6.5 0.44 10.2 0.7 2.2 1 1 1 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Nop25 PF09805.4 CCH60055.1 - 8.9 6.3 11.3 2.8 8.0 5.6 1.8 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3818 PF12825.2 CCH60056.1 - 2.6e-92 309.1 28.6 2.6e-92 309.1 19.8 3.5 3 1 0 3 3 3 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCH60056.1 - 1.3e-34 118.7 5.8 1.3e-34 118.7 4.0 3.9 4 0 0 4 4 4 1 PX-associated PX PF00787.19 CCH60056.1 - 1.7e-11 43.8 3.0 1.7e-11 43.8 2.1 2.9 2 0 0 2 2 2 1 PX domain Sec7 PF01369.15 CCH60057.1 - 3e-33 115.0 1.2 3e-33 115.0 0.8 3.2 4 0 0 4 4 4 1 Sec7 domain OTCace PF00185.19 CCH60057.1 - 0.018 14.9 0.3 0.32 10.8 0.1 2.5 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF651 PF04895.7 CCH60057.1 - 0.19 11.3 0.5 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) CKS PF01111.14 CCH60059.1 - 7.5e-35 118.5 0.0 1.1e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Spt20 PF12090.3 CCH60059.1 - 0.016 14.5 0.7 0.016 14.5 0.5 1.2 1 0 0 1 1 1 0 Spt20 family PRMT5 PF05185.11 CCH60060.1 - 1.5e-124 416.3 18.0 1.5e-124 416.3 12.5 2.5 2 1 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Tom22 PF04281.8 CCH60060.1 - 0.98 8.9 6.0 0.73 9.3 2.6 2.0 1 1 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DIL PF01843.14 CCH60061.1 - 1.5e-08 34.4 4.2 0.00037 20.3 0.6 2.8 2 0 0 2 2 2 2 DIL domain Mucin PF01456.12 CCH60061.1 - 1.7 8.4 7.0 0.5 10.1 0.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein AA_permease PF00324.16 CCH60062.1 - 8.8e-125 416.7 37.3 1e-124 416.5 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH60062.1 - 5.2e-25 87.8 38.9 7.5e-25 87.3 26.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF1712 PF08217.6 CCH60063.1 - 1e-100 337.7 67.4 2.8e-97 326.4 46.7 3.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) TFIIB PF00382.14 CCH60064.1 - 4.1e-42 141.8 2.1 1.2e-26 92.2 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CCH60064.1 - 1.2e-13 50.1 0.5 2.1e-13 49.3 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Fmp27_WPPW PF10359.4 CCH60065.1 - 4.4e-122 407.8 10.7 4.4e-122 407.8 7.4 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CCH60065.1 - 7.6e-101 338.2 5.7 7.6e-101 338.2 3.9 3.2 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CCH60065.1 - 5.7e-47 159.5 0.2 1.8e-46 157.9 0.1 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCH60065.1 - 1.6e-37 128.6 2.4 1.3e-36 125.7 1.7 2.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCH60065.1 - 8.8e-18 64.6 0.1 8.8e-18 64.6 0.1 4.2 5 0 0 5 5 5 1 RNA pol II promoter Fmp27 protein domain PilJ PF13675.1 CCH60065.1 - 0.018 15.3 0.8 0.063 13.5 0.6 1.9 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 CCH60065.1 - 2 7.9 9.0 0.67 9.5 4.0 1.8 2 0 0 2 2 2 0 IncA protein NESP55 PF06390.7 CCH60065.1 - 2.3 7.5 9.7 4.5 6.5 6.7 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 CCH60065.1 - 7.2 6.4 4.9 14 5.5 3.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Med18 PF09637.5 CCH60067.1 - 9.4e-60 202.2 3.7 3.1e-58 197.2 2.6 2.1 1 1 0 1 1 1 1 Med18 protein VMA21 PF09446.5 CCH60068.1 - 1.2e-16 60.3 8.5 1.5e-16 60.0 5.9 1.1 1 0 0 1 1 1 1 VMA21-like domain PrsW-protease PF13367.1 CCH60068.1 - 0.0094 15.1 1.6 0.01 15.0 1.1 1.0 1 0 0 1 1 1 1 Protease prsW family DUF3816 PF12822.2 CCH60068.1 - 0.026 14.4 1.3 0.031 14.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF1430 PF07242.6 CCH60068.1 - 0.25 11.4 1.9 0.29 11.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) SecY PF00344.15 CCH60069.1 - 1.4e-53 182.0 23.3 1.8e-53 181.6 16.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCH60069.1 - 0.00056 19.3 0.0 0.0019 17.6 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p Ninjurin PF04923.7 CCH60069.1 - 0.28 10.9 8.2 0.48 10.1 0.7 2.7 2 0 0 2 2 2 0 Ninjurin MRP-L27 PF09809.4 CCH60070.1 - 4.1e-28 97.2 1.8 4.6e-28 97.1 0.7 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 Peptidase_M20 PF01546.23 CCH60071.1 - 3e-25 88.8 0.0 4.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 CCH60071.1 - 2.2e-13 49.5 3.9 0.0053 16.5 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 CCH60071.1 - 5.1e-11 42.2 0.0 1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 CCH60071.1 - 0.0018 17.0 0.0 0.0033 16.2 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Nup160 PF11715.3 CCH60071.1 - 0.007 14.5 0.2 0.26 9.3 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 RCC1 PF00415.13 CCH60072.1 - 5.7e-16 58.4 0.0 1.4e-05 25.2 0.2 5.4 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCH60072.1 - 9.1e-16 57.0 5.1 1.6e-06 27.6 0.3 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CCH60072.1 - 0.0025 17.4 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like CBM_X PF06204.6 CCH60072.1 - 0.053 12.9 1.2 11 5.5 0.1 2.8 2 0 0 2 2 2 0 Putative carbohydrate binding domain Paf1 PF03985.8 CCH60073.1 - 3.8e-137 457.5 12.8 4.3e-137 457.4 8.9 1.0 1 0 0 1 1 1 1 Paf1 APC_CDC26 PF10471.4 CCH60074.1 - 1.2 9.9 5.4 0.21 12.3 0.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Cyclin_N PF00134.18 CCH60075.1 - 5e-37 126.2 0.2 7.2e-34 116.0 0.3 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCH60075.1 - 1.7e-24 86.0 0.0 4.1e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CCH60076.1 - 5.4e-39 132.6 4.3 1.7e-38 131.0 1.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCH60076.1 - 6.7e-15 55.0 0.5 6.7e-15 55.0 0.4 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF2683 PF10884.3 CCH60076.1 - 0.044 13.7 0.2 0.22 11.4 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) A_deaminase PF00962.17 CCH60077.1 - 2e-20 73.0 0.0 2.1e-08 33.4 0.0 3.9 3 1 0 3 3 3 2 Adenosine/AMP deaminase DUF619 PF04768.8 CCH60078.1 - 1e-46 158.4 0.6 3.3e-46 156.8 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Peptidase_M28 PF04389.12 CCH60079.1 - 3e-33 115.0 0.0 5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CCH60079.1 - 5.9e-07 29.1 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 PA domain DnaJ PF00226.26 CCH60080.1 - 2.4e-20 72.0 5.0 2.4e-20 72.0 3.5 2.6 3 0 0 3 3 3 1 DnaJ domain WBP-1 PF11669.3 CCH60080.1 - 9.2 6.4 7.4 13 5.9 0.5 3.1 2 0 0 2 2 2 0 WW domain-binding protein 1 Mem_trans PF03547.13 CCH60081.1 - 1e-61 208.3 7.3 1.3e-61 208.0 5.1 1.1 1 0 0 1 1 1 1 Membrane transport protein SMC_hinge PF06470.8 CCH60082.1 - 1.5e-32 112.0 0.1 7.1e-32 109.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 CCH60082.1 - 1.9e-12 46.8 90.1 8e-11 41.5 62.4 3.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCH60082.1 - 3.2e-10 40.4 3.3 3.2e-10 40.4 2.3 5.2 2 1 4 6 6 6 1 AAA domain DUF3584 PF12128.3 CCH60082.1 - 4.3 4.5 94.4 0.068 10.5 27.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) CAP PF00188.21 CCH60083.1 - 3.6e-20 72.6 1.9 6.5e-20 71.8 1.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NB PF04159.8 CCH60083.1 - 0.48 10.2 4.5 0.53 10.0 2.1 1.9 1 1 0 1 1 1 0 NB glycoprotein KH_1 PF00013.24 CCH60084.1 - 2.7e-61 203.0 33.4 3.6e-11 42.5 0.1 11.5 13 0 0 13 13 13 7 KH domain KH_3 PF13014.1 CCH60084.1 - 6.2e-41 137.4 16.5 4.6e-07 29.3 0.1 10.0 11 0 0 11 11 11 6 KH domain KH_2 PF07650.12 CCH60084.1 - 7e-10 38.3 11.9 0.00096 18.6 0.1 6.5 6 0 0 6 6 6 3 KH domain BMC PF00936.14 CCH60084.1 - 0.0032 17.1 0.0 59 3.4 0.0 5.4 6 0 0 6 6 6 0 BMC domain HSP20 PF00011.16 CCH60084.1 - 0.0075 16.1 1.7 6.8 6.6 0.2 4.0 2 1 1 3 3 3 2 Hsp20/alpha crystallin family Ras PF00071.17 CCH60085.1 - 2.9e-57 192.5 1.2 3.4e-57 192.3 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH60085.1 - 3.5e-22 79.1 0.7 4.9e-22 78.6 0.1 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCH60085.1 - 1.8e-16 59.8 0.5 2.4e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCH60085.1 - 6.3e-08 32.2 0.1 1.3e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCH60085.1 - 6.6e-08 31.9 0.3 8.5e-08 31.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCH60085.1 - 2.2e-06 27.6 0.0 3.6e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCH60085.1 - 0.0083 15.3 0.1 0.019 14.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 CCH60085.1 - 0.028 13.1 3.5 4 6.0 0.5 3.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 CCH60085.1 - 0.071 13.0 0.1 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.18 CCH60085.1 - 0.082 12.7 1.5 0.2 11.4 1.1 2.1 1 1 0 1 1 1 0 Dynamin family Mitofilin PF09731.4 CCH60086.1 - 1.2e-83 281.7 18.5 2.7e-76 257.4 10.5 2.0 1 1 0 2 2 2 2 Mitochondrial inner membrane protein Tubulin_3 PF14881.1 CCH60086.1 - 0.044 13.2 1.4 0.082 12.3 0.5 1.8 2 0 0 2 2 2 0 Tubulin domain Apolipoprotein PF01442.13 CCH60086.1 - 0.21 11.0 7.5 0.96 8.9 5.2 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FKBP_N PF01346.13 CCH60086.1 - 2.2 8.3 14.2 12 5.9 7.3 2.9 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HSCB_C PF07743.8 CCH60086.1 - 5.3 7.5 12.8 16 6.0 0.0 3.7 2 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain IBR PF01485.16 CCH60087.1 - 3.3e-17 62.0 47.7 2.6e-10 40.0 7.4 4.0 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 CCH60087.1 - 7.4e-06 25.5 13.8 7.4e-06 25.5 9.6 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH60087.1 - 0.00013 21.5 8.3 0.00013 21.5 5.8 4.2 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH60087.1 - 0.00021 21.0 9.6 0.00021 21.0 6.6 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH60087.1 - 0.00034 20.5 11.9 0.00034 20.5 8.3 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH60087.1 - 0.0032 17.1 5.8 0.0032 17.1 4.0 3.2 2 0 0 2 2 2 1 RING-type zinc-finger DUF3808 PF10300.4 CCH60088.1 - 2.1e-157 524.4 0.9 4.5e-157 523.3 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.1 CCH60088.1 - 0.00036 20.3 0.9 0.047 13.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCH60088.1 - 0.75 10.5 0.0 0.75 10.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Clat_adaptor_s PF01217.15 CCH60089.1 - 0.1 12.3 0.9 0.17 11.5 0.6 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain EF-hand_4 PF12763.2 CCH60090.1 - 0.0014 18.2 0.1 0.0014 18.2 0.1 3.1 5 0 0 5 5 5 1 Cytoskeletal-regulatory complex EF hand Arrestin_N PF00339.24 CCH60091.1 - 1.1e-05 25.2 0.5 1.1e-05 25.2 0.4 4.6 5 0 0 5 5 5 1 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.10 CCH60092.1 - 1.4e-82 277.4 4.1 1.4e-82 277.4 2.8 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit SAS4 PF15460.1 CCH60092.1 - 0.21 11.4 2.2 0.35 10.7 0.3 2.3 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 RNA_lig_T4_1 PF09511.5 CCH60093.1 - 1.4e-78 263.3 0.2 3e-78 262.3 0.2 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CCH60093.1 - 6.6e-69 231.0 0.1 2.4e-68 229.2 0.0 2.0 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CCH60093.1 - 3.1e-57 193.7 2.2 4.7e-57 193.1 1.5 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain NTR2 PF15458.1 CCH60094.1 - 1.2e-21 77.1 17.0 1.3e-21 76.9 11.8 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Enkurin PF13864.1 CCH60094.1 - 2 8.6 7.7 0.6 10.3 0.5 2.5 3 0 0 3 3 3 0 Calmodulin-binding PRANC PF09372.5 CCH60094.1 - 2.1 8.3 9.6 2.4 8.1 0.5 2.7 3 0 0 3 3 3 0 PRANC domain BTV_NS2 PF04514.7 CCH60094.1 - 8 5.2 11.5 11 4.7 7.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GWT1 PF06423.7 CCH60095.1 - 1.4e-44 151.4 3.5 1.4e-44 151.4 2.5 3.0 2 1 1 3 3 3 1 GWT1 Ion_trans_2 PF07885.11 CCH60096.1 - 3e-26 90.9 40.4 2.3e-16 59.2 8.7 3.8 3 0 0 3 3 3 2 Ion channel FA_desaturase PF00487.19 CCH60096.1 - 0.66 9.3 7.5 8 5.8 0.1 2.5 2 0 0 2 2 2 0 Fatty acid desaturase Na_H_Exchanger PF00999.16 CCH60097.1 - 3.7e-65 219.9 32.2 5.7e-65 219.3 22.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF485 PF04341.7 CCH60097.1 - 0.051 13.2 0.2 0.051 13.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Pkinase PF00069.20 CCH60098.1 - 1.4e-66 224.3 0.0 2.6e-66 223.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60098.1 - 3.9e-45 153.9 0.0 8.4e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH60098.1 - 2.6e-09 36.4 0.0 2.4e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like PTPLA PF04387.9 CCH60099.1 - 2.4e-48 163.6 9.0 3.3e-48 163.2 6.2 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.10 CCH60100.1 - 7.9e-166 552.3 17.7 7.9e-166 552.3 12.3 3.7 3 1 1 4 4 4 1 SIT4 phosphatase-associated protein ChAPs PF09295.5 CCH60101.1 - 8e-39 133.5 10.4 4.1e-29 101.5 4.4 2.6 2 1 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCH60101.1 - 0.0088 15.6 0.0 1.4 8.6 0.0 2.7 3 0 0 3 3 3 2 TPR repeat Apc3 PF12895.2 CCH60101.1 - 0.062 13.4 0.4 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Arg_repressor PF01316.16 CCH60102.1 - 0.022 14.3 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain RabGAP-TBC PF00566.13 CCH60104.1 - 5.4e-12 45.6 7.6 5.4e-12 45.6 5.3 2.6 3 1 0 3 3 3 1 Rab-GTPase-TBC domain His_Phos_1 PF00300.17 CCH60105.1 - 1.4e-41 142.1 0.0 1.9e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DBR1 PF05011.8 CCH60106.1 - 2.3e-12 47.0 1.8 6.3e-12 45.5 0.0 2.1 1 1 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CCH60106.1 - 1.2e-06 28.0 1.5 7e-06 25.5 1.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Aa_trans PF01490.13 CCH60107.1 - 1e-88 297.5 34.5 1.2e-88 297.3 23.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CCH60107.1 - 5.5e-06 25.1 35.9 9.2e-06 24.4 24.9 1.3 1 0 0 1 1 1 1 Amino acid permease TarH PF02203.10 CCH60107.1 - 0.11 12.2 0.4 0.5 10.1 0.2 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue AAA PF00004.24 CCH60108.1 - 2.1e-40 137.9 0.0 4.9e-40 136.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH60108.1 - 5.8e-06 26.4 0.0 0.00099 19.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CCH60108.1 - 2.5e-05 24.0 0.0 0.00012 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH60108.1 - 0.00014 21.9 0.0 0.00039 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 CCH60108.1 - 0.00033 20.6 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCH60108.1 - 0.00098 19.9 0.1 0.0038 18.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CCH60108.1 - 0.0012 17.8 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 CCH60108.1 - 0.0044 17.3 0.2 0.062 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCH60108.1 - 0.0054 15.8 0.0 0.0095 14.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCH60108.1 - 0.0054 16.4 0.4 0.013 15.2 0.1 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_28 PF13521.1 CCH60108.1 - 0.0094 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCH60108.1 - 0.013 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CCH60108.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCH60108.1 - 0.02 15.0 0.0 0.072 13.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_14 PF13173.1 CCH60108.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCH60108.1 - 0.025 14.2 0.1 4.7 6.8 0.0 2.5 2 1 1 3 3 2 0 Archaeal ATPase IstB_IS21 PF01695.12 CCH60108.1 - 0.031 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CCH60108.1 - 0.036 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCH60108.1 - 0.04 13.0 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CCH60108.1 - 0.04 13.9 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 CCH60108.1 - 0.048 12.3 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_pol_Rbc25 PF08292.7 CCH60109.1 - 1.9e-45 154.0 0.3 2.5e-45 153.6 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CCH60109.1 - 1.6e-21 76.2 0.0 2.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCH60109.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain LTV PF04180.9 CCH60110.1 - 1e-113 381.0 34.7 1.2e-113 380.8 24.0 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.6 CCH60111.1 - 3.6e-74 248.9 5.1 4e-74 248.8 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DivIC PF04977.10 CCH60111.1 - 0.016 14.6 5.4 0.092 12.2 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.13 CCH60111.1 - 0.03 14.0 1.5 0.03 14.0 1.1 2.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper ADSL_C PF10397.4 CCH60111.1 - 0.19 11.7 1.0 0.42 10.6 0.1 2.1 2 2 0 2 2 2 0 Adenylosuccinate lyase C-terminus Tricorn_C1 PF14684.1 CCH60111.1 - 0.2 11.5 0.7 8.2 6.3 0.0 2.6 2 1 0 2 2 2 0 Tricorn protease C1 domain Ribosomal_L29 PF00831.18 CCH60111.1 - 0.38 10.4 5.1 4.7 6.9 0.1 2.9 3 0 0 3 3 3 0 Ribosomal L29 protein MbeD_MobD PF04899.7 CCH60111.1 - 0.53 10.2 4.9 0.84 9.5 0.6 2.9 4 0 0 4 4 4 0 MbeD/MobD like Uds1 PF15456.1 CCH60111.1 - 0.74 9.8 3.5 0.45 10.5 1.0 1.7 2 0 0 2 2 2 0 Up-regulated During Septation SPX PF03105.14 CCH60111.1 - 0.8 9.4 7.4 5.8 6.6 4.4 2.4 1 1 0 1 1 1 0 SPX domain Glyco_hydro_4C PF11975.3 CCH60111.1 - 0.99 9.1 3.8 0.7 9.6 0.8 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain FlgN PF05130.7 CCH60111.1 - 1.6 8.9 5.7 1 9.5 2.5 1.7 2 0 0 2 2 2 0 FlgN protein SYCE1 PF15233.1 CCH60111.1 - 1.9 8.3 7.4 3.8 7.4 5.1 1.9 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 DivIVA PF05103.8 CCH60111.1 - 2.4 8.2 7.0 0.74 9.8 2.7 1.7 2 0 0 2 2 2 0 DivIVA protein CENP-Q PF13094.1 CCH60111.1 - 3.5 7.6 8.4 3.1 7.7 3.9 2.3 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PUF PF00806.14 CCH60112.1 - 3.3e-34 114.4 5.3 0.00013 21.2 0.0 8.6 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat OSCP PF00213.13 CCH60112.1 - 0.017 14.9 0.9 0.58 9.9 0.0 3.1 2 1 2 4 4 4 0 ATP synthase delta (OSCP) subunit Cpn60_TCP1 PF00118.19 CCH60113.1 - 6.5e-136 453.7 8.0 7.5e-136 453.5 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 CCH60113.1 - 0.065 13.3 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor MFS_1 PF07690.11 CCH60114.1 - 1.5e-33 115.9 24.2 1.1e-32 113.1 16.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SPRY PF00622.23 CCH60115.1 - 0.00045 20.2 0.0 0.0012 18.9 0.0 1.7 1 0 0 1 1 1 1 SPRY domain COX5A PF02284.11 CCH60116.1 - 1e-46 157.3 0.5 1.5e-46 156.7 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PIF1 PF05970.9 CCH60117.1 - 5.1e-55 186.8 4.7 7.4e-53 179.7 3.3 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CCH60117.1 - 1.8e-14 53.7 0.0 4.4e-14 52.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH60117.1 - 4e-05 23.7 0.1 0.00011 22.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCH60117.1 - 0.0009 18.2 0.3 0.0022 16.9 0.2 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CCH60117.1 - 0.0025 17.8 0.0 0.053 13.6 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCH60117.1 - 0.0035 17.0 0.2 0.0092 15.7 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 CCH60117.1 - 0.0038 16.4 0.1 0.023 13.9 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein FtsK_SpoIIIE PF01580.13 CCH60117.1 - 0.0058 16.1 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CCH60117.1 - 0.045 12.9 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCH60117.1 - 0.049 13.5 0.0 0.25 11.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 CCH60118.1 - 5.5e-62 209.2 0.0 7.9e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60118.1 - 5.2e-26 91.2 0.0 8.2e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCH60118.1 - 0.027 13.5 0.1 0.059 12.4 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH60118.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PC_rep PF01851.17 CCH60119.1 - 4.4e-25 86.4 8.5 1e-07 31.7 0.1 7.7 7 0 0 7 7 7 5 Proteasome/cyclosome repeat Ribosomal_S27e PF01667.12 CCH60120.1 - 3.7e-30 103.2 2.6 4.8e-30 102.8 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CCH60120.1 - 4.1e-05 23.3 0.7 5e-05 23.0 0.5 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CCH60120.1 - 0.056 12.7 4.3 0.082 12.2 3.0 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CCH60120.1 - 0.21 11.2 1.2 11 5.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCH60120.1 - 0.22 11.2 1.2 11 5.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rsm22 PF09243.5 CCH60121.1 - 5.5e-23 81.3 0.0 1.1e-07 31.1 0.0 4.2 4 0 0 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 CCH60121.1 - 0.011 15.5 0.0 0.054 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain HGTP_anticodon2 PF12745.2 CCH60122.1 - 6.3e-93 310.8 7.5 6.3e-93 310.8 5.2 2.1 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 CCH60122.1 - 4.4e-69 232.5 1.9 2.4e-42 144.8 0.1 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60122.1 - 9.6e-39 133.0 0.2 3.8e-21 75.3 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 CCH60122.1 - 2.8e-18 65.8 4.3 1.1e-17 63.8 3.0 2.2 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CCH60122.1 - 3.2e-15 55.9 0.0 1e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 CCH60122.1 - 1.6e-06 27.3 0.0 0.039 12.9 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCH60122.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L6e PF01159.14 CCH60122.1 - 0.1 12.8 6.3 1.7 8.9 3.0 3.2 2 0 0 2 2 2 0 Ribosomal protein L6e MRP-S26 PF14943.1 CCH60122.1 - 0.81 9.2 14.3 2.7 7.4 9.9 1.9 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PAP2 PF01569.16 CCH60123.1 - 6.3e-24 84.0 1.6 6.3e-24 84.0 1.1 1.6 1 1 1 2 2 2 1 PAP2 superfamily DsbB PF02600.11 CCH60123.1 - 0.0043 16.8 2.4 0.058 13.1 0.3 2.3 2 0 0 2 2 2 2 Disulfide bond formation protein DsbB MAGE PF01454.14 CCH60124.1 - 1.4e-33 115.8 0.8 2.1e-33 115.3 0.6 1.3 1 0 0 1 1 1 1 MAGE family FAD_binding_1 PF00667.15 CCH60125.1 - 1.9e-63 213.8 0.0 2.7e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCH60125.1 - 4.4e-25 88.3 0.7 7.7e-25 87.5 0.5 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCH60125.1 - 3.6e-21 75.7 0.0 1.1e-20 74.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.5 CCH60125.1 - 0.034 12.8 0.0 0.064 11.9 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Flavodoxin_5 PF12724.2 CCH60125.1 - 0.1 12.6 0.0 0.41 10.6 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain HAD_2 PF13419.1 CCH60126.1 - 8.2e-12 45.6 0.0 1.4e-11 44.8 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH60126.1 - 2e-08 33.8 0.1 3.2e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCH60126.1 - 0.0034 17.5 0.0 0.0048 17.0 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH60126.1 - 0.011 16.1 0.1 0.22 11.8 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 CCH60126.1 - 0.058 12.9 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase GDPD_2 PF13653.1 CCH60126.1 - 0.089 13.0 0.5 14 6.0 0.0 2.9 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family RNase_H2-Ydr279 PF09468.5 CCH60127.1 - 9.4e-25 87.4 1.0 1.2e-24 87.1 0.7 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Nramp PF01566.13 CCH60128.1 - 2.4e-92 309.4 17.5 3.5e-92 308.9 12.1 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Med20 PF08612.6 CCH60129.1 - 5.9e-30 104.0 0.1 6.6e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex XisH PF08814.5 CCH60129.1 - 0.09 12.7 0.5 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 XisH protein DUF2697 PF10906.3 CCH60129.1 - 0.11 12.5 0.2 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2697) CTD_bind PF04818.8 CCH60130.1 - 6e-11 42.4 0.0 1.7e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF966 PF06136.8 CCH60130.1 - 0.39 10.0 13.6 0.68 9.2 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF572 PF04502.8 CCH60130.1 - 1.6 7.8 15.6 3 6.9 10.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Aldedh PF00171.17 CCH60131.1 - 1e-110 370.2 0.0 1.3e-110 369.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNB PF00773.14 CCH60132.1 - 9.7e-49 166.3 3.2 3e-48 164.7 2.2 1.9 1 0 0 1 1 1 1 RNB domain OB_RNB PF08206.6 CCH60132.1 - 0.018 14.5 0.2 1.1 8.7 0.0 2.9 3 0 0 3 3 3 0 Ribonuclease B OB domain Aldedh PF00171.17 CCH60133.1 - 4.7e-94 315.3 0.0 9.2e-94 314.3 0.0 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family SBDS PF01172.13 CCH60133.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Brr6_like_C_C PF10104.4 CCH60134.1 - 7.3e-40 135.6 4.9 1.1e-39 134.9 3.4 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain HDA2-3 PF11496.3 CCH60135.1 - 1.2e-64 218.0 15.9 1.2e-64 218.0 11.0 2.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Myosin_tail_1 PF01576.14 CCH60135.1 - 0.069 10.8 29.8 0.038 11.7 11.4 2.3 1 1 1 2 2 2 0 Myosin tail Laminin_II PF06009.7 CCH60135.1 - 4.1 7.1 25.7 0.037 13.8 4.4 3.8 3 1 0 3 3 3 0 Laminin Domain II Sec23_trunk PF04811.10 CCH60136.1 - 1.4e-15 57.2 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain PHD PF00628.24 CCH60136.1 - 0.011 15.4 2.1 0.026 14.2 1.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-Sec23_Sec24 PF04810.10 CCH60136.1 - 0.053 13.0 1.5 0.14 11.7 1.1 1.8 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger Mhr1 PF12829.2 CCH60137.1 - 3.4e-35 119.7 0.1 6.1e-35 118.9 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination OSCP PF00213.13 CCH60138.1 - 1.9e-42 145.0 3.6 2.2e-42 144.8 2.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PIH1 PF08190.7 CCH60139.1 - 5.5e-24 85.2 11.4 2.6e-23 82.9 7.9 1.8 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 PIG-F PF06699.6 CCH60140.1 - 1e-28 100.6 15.1 1.7e-27 96.6 10.5 2.1 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2463 PF09591.5 CCH60140.1 - 0.021 14.4 10.0 0.03 13.8 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Nucleos_tra2_N PF01773.15 CCH60140.1 - 0.25 11.7 2.5 0.82 10.0 0.4 2.3 1 1 1 2 2 2 0 Na+ dependent nucleoside transporter N-terminus AIM24 PF01987.12 CCH60141.1 - 3.2e-11 43.1 0.0 1e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.13 CCH60142.1 - 2.8e-07 30.3 7.7 5e-07 29.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_PIX PF03955.9 CCH60142.1 - 2.2 8.8 6.1 11 6.5 0.7 3.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Pro_isomerase PF00160.16 CCH60143.1 - 4.1e-45 153.7 0.2 5.2e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Epimerase PF01370.16 CCH60144.1 - 5.5e-19 68.5 0.1 1.1e-18 67.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCH60144.1 - 1.2e-10 40.8 0.0 2.2e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CCH60144.1 - 2.1e-07 29.9 0.0 2.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCH60144.1 - 4.2e-07 30.0 0.0 7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH60144.1 - 3.4e-05 23.5 0.0 5.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCH60144.1 - 0.00012 22.1 0.0 0.00025 21.0 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCH60144.1 - 0.012 14.9 0.0 0.029 13.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DUF3463 PF11946.3 CCH60144.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) Epimerase PF01370.16 CCH60145.1 - 3.1e-16 59.5 0.0 4.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCH60145.1 - 7.9e-12 44.4 0.3 1.3e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCH60145.1 - 6.8e-11 41.5 0.0 2.1e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCH60145.1 - 7.3e-07 29.3 0.1 1.7e-06 28.1 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCH60145.1 - 5.9e-06 26.2 0.0 9.9e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCH60145.1 - 6.9e-06 25.1 0.4 4.8e-05 22.4 0.2 2.3 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CCH60145.1 - 2.6e-05 23.5 0.3 0.00044 19.5 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 CCH60145.1 - 0.00023 20.9 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CCH60145.1 - 0.036 12.9 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 CCH60145.1 - 0.088 13.1 0.1 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCH60145.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 CCH60146.1 - 3.9e-11 42.8 0.3 1.2e-10 41.2 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCH60146.1 - 3.1e-10 39.2 0.0 4.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCH60146.1 - 9.1e-09 34.6 0.0 3.7e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCH60146.1 - 6.2e-07 29.6 0.0 2e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 CCH60146.1 - 0.00083 19.3 0.1 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCH60146.1 - 0.0073 15.9 0.0 0.03 13.9 0.0 1.9 2 1 0 2 2 2 1 KR domain NmrA PF05368.8 CCH60146.1 - 0.038 13.2 0.1 0.1 11.8 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 CCH60146.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HIT PF01230.18 CCH60147.1 - 4.3e-24 84.8 0.1 1.2e-23 83.4 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CCH60147.1 - 3e-05 24.2 0.1 5.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Med21 PF11221.3 CCH60148.1 - 9.7e-51 171.5 3.8 1.1e-50 171.3 2.6 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex TMCO5 PF14992.1 CCH60148.1 - 0.0012 18.0 2.1 0.0013 17.9 1.4 1.2 1 0 0 1 1 1 1 TMCO5 family Med9 PF07544.8 CCH60148.1 - 0.0037 16.9 2.9 0.01 15.5 2.0 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Katanin_con80 PF13925.1 CCH60148.1 - 0.0078 15.9 0.5 0.0078 15.9 0.4 1.5 2 0 0 2 2 2 1 con80 domain of Katanin Sipho_Gp157 PF05565.6 CCH60148.1 - 0.0079 15.7 1.1 0.012 15.2 0.8 1.3 1 0 0 1 1 1 1 Siphovirus Gp157 DUF1640 PF07798.6 CCH60148.1 - 0.019 15.0 4.5 0.021 14.8 2.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2200 PF09966.4 CCH60148.1 - 0.023 14.5 0.2 0.54 10.1 0.0 2.2 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Cortex-I_coil PF09304.5 CCH60148.1 - 0.066 13.2 3.3 0.12 12.4 2.3 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF1492 PF07374.6 CCH60148.1 - 0.094 12.8 4.1 1.8 8.6 1.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) APG6 PF04111.7 CCH60148.1 - 0.59 9.1 4.3 0.79 8.7 3.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 CCH60148.1 - 0.75 10.1 5.8 9.9 6.5 1.0 2.8 1 1 2 3 3 3 0 Snapin/Pallidin SlyX PF04102.7 CCH60148.1 - 6.4 7.2 8.1 10 6.5 0.1 3.2 2 1 1 3 3 3 0 SlyX HSP70 PF00012.15 CCH60151.1 - 6.8e-73 245.5 1.2 6.8e-73 245.5 0.8 1.6 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCH60151.1 - 7.8e-11 41.1 0.0 1.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DEAD PF00270.24 CCH60152.1 - 4.7e-47 159.6 0.0 9.9e-47 158.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH60152.1 - 1.5e-26 92.0 0.0 4e-26 90.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH60152.1 - 0.00025 20.9 4.4 0.0029 17.4 0.0 2.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCH60152.1 - 0.0039 16.9 0.0 1.8 8.3 0.0 3.0 3 0 0 3 3 3 2 Part of AAA domain DUF1510 PF07423.6 CCH60152.1 - 5.9 6.1 21.4 9.7 5.4 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FYVE PF01363.16 CCH60153.1 - 5.3e-16 58.2 13.8 5.3e-16 58.2 9.5 3.2 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CCH60153.1 - 9.9e-11 41.3 1.5 9.9e-11 41.3 1.0 3.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 CCH60153.1 - 0.00052 19.6 0.4 0.00052 19.6 0.2 4.3 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CCH60153.1 - 0.014 15.3 2.4 0.014 15.3 1.7 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCH60153.1 - 2.3 8.3 21.3 0.084 12.9 3.0 3.7 3 1 0 3 3 3 0 RING-H2 zinc finger Tmemb_55A PF09788.4 CCH60153.1 - 3.1 6.8 14.1 0.037 13.1 1.5 2.7 2 1 1 3 3 3 0 Transmembrane protein 55A BHD_1 PF10403.4 CCH60154.1 - 1.2e-13 50.2 0.1 3.7e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 CCH60154.1 - 3.9e-10 39.2 0.0 1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CCH60154.1 - 3.7e-06 26.3 0.1 1.5e-05 24.4 0.1 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 CCH60154.1 - 8.4e-06 26.0 0.1 4.3e-05 23.7 0.0 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 UBA_e1_C PF09358.5 CCH60155.1 - 0.19 11.8 1.9 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain DS PF01916.12 CCH60156.1 - 4.9e-146 485.5 0.1 5.8e-146 485.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Met_10 PF02475.11 CCH60157.1 - 2.3e-74 249.3 0.0 4.5e-74 248.3 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 CCH60157.1 - 0.028 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 CCH60157.1 - 0.049 14.2 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain P53 PF00870.13 CCH60158.1 - 0.052 13.1 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 P53 DNA-binding domain Ribosomal_L24e PF01246.15 CCH60159.1 - 1.7e-29 101.4 1.8 4e-29 100.2 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Nucleoplasmin PF03066.10 CCH60159.1 - 1.2 8.5 12.4 1.6 8.2 8.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin DnaJ PF00226.26 CCH60160.1 - 2.1e-06 27.3 0.1 4.1e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCH60160.1 - 1.9e-05 24.4 0.0 2.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Pam16 SMC_Nse1 PF07574.8 CCH60161.1 - 3e-36 124.9 0.8 4e-36 124.5 0.5 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CCH60161.1 - 6.2e-08 32.5 11.8 1.5e-07 31.3 8.2 1.7 1 0 0 1 1 1 1 RING-like domain DUF327 PF03885.8 CCH60161.1 - 0.1 12.4 0.1 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF327) CMS1 PF14617.1 CCH60162.1 - 8.2e-20 70.9 14.0 8.2e-20 70.9 9.7 2.3 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit LMBR1 PF04791.11 CCH60162.1 - 0.097 11.2 1.0 0.12 10.9 0.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MFS_1 PF07690.11 CCH60163.1 - 3.4e-30 104.9 22.5 3.4e-30 104.9 15.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Ssl1 PF04056.9 CCH60165.1 - 6.8e-85 283.5 0.0 9.3e-85 283.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CCH60165.1 - 2.9e-21 75.2 11.6 2.9e-21 75.2 8.1 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CCH60165.1 - 8.1e-13 48.8 0.0 1.1e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCH60165.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Taeniidae_ag PF05596.6 CCH60165.1 - 0.052 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Taeniidae antigen IBR PF01485.16 CCH60165.1 - 1.4 8.7 17.3 0.065 13.1 4.2 2.9 2 0 0 2 2 2 0 IBR domain zf-HIT PF04438.11 CCH60165.1 - 2.4 7.8 20.2 0.36 10.5 4.5 3.3 3 0 0 3 3 3 0 HIT zinc finger Tfb4 PF03850.9 CCH60165.1 - 3.8 6.6 8.9 6 6.0 5.7 1.7 2 0 0 2 2 2 0 Transcription factor Tfb4 PP2C PF00481.16 CCH60166.1 - 4.4e-59 199.9 0.1 4.4e-59 199.9 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 CCH60166.1 - 2.2e-36 122.8 100.0 1.1e-06 28.1 2.0 14.4 10 3 5 16 16 16 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH60166.1 - 2.3e-32 110.5 89.8 4.5e-08 32.7 6.2 11.4 7 3 5 12 12 12 9 Leucine rich repeat Guanylate_cyc PF00211.15 CCH60166.1 - 1.1e-26 93.3 0.0 2.5e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CCH60166.1 - 1.9e-15 54.5 75.5 0.33 11.1 1.4 19.4 15 4 3 18 18 18 8 Leucine Rich Repeat RA PF00788.18 CCH60166.1 - 1.2e-08 35.3 0.0 3.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CCH60166.1 - 0.00027 20.6 62.7 0.75 10.2 0.3 16.6 18 0 0 18 18 18 3 Leucine rich repeat DUF2065 PF09838.4 CCH60166.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) LRR_6 PF13516.1 CCH60166.1 - 1.2 9.4 68.8 1 9.6 0.1 16.0 16 1 1 17 17 17 0 Leucine Rich repeat RNA_pol_Rpb5_C PF01191.14 CCH60167.1 - 0.053 13.1 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DUF2404 PF10296.4 CCH60168.1 - 9.4e-05 22.4 0.0 0.00022 21.2 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Pro_3_hydrox_C PF05373.6 CCH60168.1 - 0.043 13.8 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal DUF221 PF02714.10 CCH60169.1 - 1.3e-82 277.2 26.9 1.3e-82 277.2 18.6 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCH60169.1 - 6.8e-30 103.6 5.0 6.8e-30 103.6 3.4 3.0 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport MgtE PF01769.11 CCH60169.1 - 3.8 7.7 11.0 4.8 7.4 1.8 4.3 4 0 0 4 4 4 0 Divalent cation transporter RRM_1 PF00076.17 CCH60170.1 - 0.012 15.2 0.2 0.06 12.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyrophosphatase PF00719.14 CCH60171.1 - 4.2e-51 172.4 0.1 5.8e-51 172.0 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase WD40 PF00400.27 CCH60172.1 - 4.8e-17 61.1 1.4 0.0063 16.3 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 CCH60172.1 - 0.00019 21.2 0.0 0.016 14.9 0.0 2.8 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 CCH60172.1 - 0.074 10.8 0.0 2.3 5.9 0.0 2.5 2 1 1 3 3 3 0 IKI3 family CUE PF02845.11 CCH60173.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain SAP30_Sin3_bdg PF13867.1 CCH60174.1 - 3.1e-08 33.3 1.2 1.1e-05 25.2 0.2 2.5 2 1 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF364 PF04016.7 CCH60174.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Glyco_transf_20 PF00982.16 CCH60175.1 - 2.7e-157 524.0 2.5 5.3e-157 523.0 1.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCH60175.1 - 6.3e-31 107.1 0.0 1.8e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 CCH60175.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferases group 1 eIF-1a PF01176.14 CCH60176.1 - 3e-27 93.8 0.3 4.3e-27 93.3 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 CCH60176.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Homeobox_KN PF05920.6 CCH60177.1 - 7.9e-17 60.6 0.4 7.9e-17 60.6 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CCH60177.1 - 2e-05 24.0 0.8 0.00013 21.4 0.1 2.3 2 0 0 2 2 2 1 Homeobox domain RCC1 PF00415.13 CCH60179.1 - 2e-56 188.0 1.1 1.5e-08 34.6 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCH60179.1 - 2.8e-36 122.3 28.4 2.9e-08 33.0 0.1 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 CCH60179.1 - 0.044 13.2 0.1 32 4.1 0.0 3.4 3 0 0 3 3 3 0 Putative carbohydrate binding domain Bystin PF05291.6 CCH60180.1 - 4e-121 403.6 0.0 7.2e-121 402.7 0.0 1.4 1 0 0 1 1 1 1 Bystin Daxx PF03344.10 CCH60180.1 - 2.9 6.2 19.3 4.1 5.7 13.4 1.2 1 0 0 1 1 1 0 Daxx Family Use1 PF09753.4 CCH60181.1 - 1.2e-11 44.5 2.6 1.9e-11 43.9 1.8 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF1180 PF06679.7 CCH60181.1 - 0.018 14.9 0.5 3.9 7.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Membr_traf_MHD PF10540.4 CCH60181.1 - 0.033 13.9 1.3 0.094 12.5 0.9 1.9 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain Bacillus_HBL PF05791.6 CCH60181.1 - 0.12 11.6 17.3 0.064 12.6 0.7 2.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Epsilon_antitox PF08998.6 CCH60181.1 - 1.5 8.8 9.3 0.22 11.4 2.4 2.3 2 0 0 2 2 2 0 Bacterial epsilon antitoxin Lipoprotein_3 PF00938.12 CCH60181.1 - 5.8 6.7 10.5 3 7.6 2.0 3.4 2 1 2 4 4 4 0 Lipoprotein MMR_HSR1 PF01926.18 CCH60182.1 - 1e-16 60.9 0.7 1.4e-14 54.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH60182.1 - 6.7e-08 31.9 0.3 6.3e-06 25.5 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 CCH60182.1 - 0.00014 21.0 0.1 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCH60182.1 - 0.001 18.2 0.1 0.0022 17.1 0.1 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CCH60182.1 - 0.0027 18.1 0.7 0.079 13.4 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCH60182.1 - 0.18 11.5 9.5 0.028 14.2 1.0 3.4 3 1 0 3 3 3 0 Dynamin family SNF2_N PF00176.18 CCH60183.1 - 4.8e-80 268.5 0.3 4.8e-80 268.5 0.2 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCH60183.1 - 1.5e-41 140.8 1.3 1.5e-41 140.8 0.9 3.4 4 1 1 5 5 5 1 SLIDE HAND PF09110.6 CCH60183.1 - 2.3e-31 108.5 6.4 2.3e-31 108.5 4.4 3.3 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CCH60183.1 - 5.6e-15 54.9 0.0 1.9e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH60183.1 - 2.4e-08 34.0 5.4 1.3e-07 31.6 0.0 3.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCH60183.1 - 7.7e-06 25.4 0.0 3.2e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 CCH60183.1 - 0.0042 16.5 0.2 0.013 14.9 0.1 1.8 1 0 0 1 1 1 1 DEAD_2 rve PF00665.21 CCH60184.1 - 8.2e-13 48.5 0.0 3.3e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotrans_gag PF03732.12 CCH60185.1 - 3.9e-14 52.4 0.1 2.4e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 CCH60185.1 - 0.0097 15.3 0.8 0.0097 15.3 0.6 2.2 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC PF00098.18 CCH60185.1 - 0.011 15.6 1.4 0.027 14.4 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCH60185.1 - 0.2 11.3 5.3 0.13 12.0 2.3 1.7 2 0 0 2 2 2 0 Zinc knuckle Glyco_hydro_76 PF03663.9 CCH60186.1 - 2.2e-138 461.6 14.7 3.1e-138 461.1 10.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DASH_Dam1 PF08653.5 CCH60187.1 - 1.9e-24 85.1 0.6 1.9e-24 85.1 0.4 2.3 2 0 0 2 2 2 1 DASH complex subunit Dam1 SH2_2 PF14633.1 CCH60188.1 - 4.7e-104 346.2 3.8 4.7e-104 346.2 2.6 3.4 4 1 1 5 5 5 1 SH2 domain YqgF PF14639.1 CCH60188.1 - 1.4e-63 212.9 0.0 6.5e-63 210.7 0.0 2.3 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CCH60188.1 - 8.2e-50 167.7 5.1 8.2e-50 167.7 3.5 4.2 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 CCH60188.1 - 1.9e-44 150.0 0.0 7.9e-44 148.0 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CCH60188.1 - 9.3e-35 119.2 3.5 9.3e-35 119.2 2.4 3.2 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 CCH60188.1 - 1.7e-22 79.4 20.4 1.7e-22 79.4 14.1 5.7 5 1 1 6 6 6 2 Acidic N-terminal SPT6 SH2 PF00017.19 CCH60188.1 - 7.2e-13 48.1 0.1 2.4e-12 46.4 0.0 2.0 1 0 0 1 1 1 1 SH2 domain LSM14 PF12701.2 CCH60189.1 - 2.1e-24 85.1 0.0 2.1e-24 85.1 0.0 2.4 3 0 0 3 3 3 1 Scd6-like Sm domain FDF PF09532.5 CCH60189.1 - 3.7e-13 49.9 9.5 3.7e-13 49.9 6.6 3.8 2 1 1 3 3 3 1 FDF domain SM-ATX PF14438.1 CCH60189.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain WD40 PF00400.27 CCH60190.1 - 2.5e-06 27.1 0.0 0.031 14.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat CNH PF00780.17 CCH60190.1 - 0.0027 17.1 2.3 0.013 14.9 0.1 2.3 2 0 0 2 2 2 1 CNH domain Ribosom_S12_S23 PF00164.20 CCH60191.1 - 4.7e-37 126.1 0.2 6e-37 125.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nup54 PF13874.1 CCH60192.1 - 6.4e-43 145.8 4.7 6.4e-43 145.8 3.3 2.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CCH60192.1 - 4.7e-24 84.7 187.1 5.1e-11 42.8 33.6 3.9 2 1 3 5 5 5 4 Nucleoporin FG repeat region Ammonium_transp PF00909.16 CCH60193.1 - 9.1e-119 396.4 20.7 1.1e-118 396.2 14.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SDA1 PF05285.7 CCH60193.1 - 0.44 9.7 15.7 0.57 9.4 10.9 1.1 1 0 0 1 1 1 0 SDA1 SelP_N PF04592.9 CCH60193.1 - 1.5 8.1 23.3 2.3 7.5 16.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lin-8 PF03353.10 CCH60193.1 - 4.2 6.5 13.6 5.9 6.0 9.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.17 CCH60193.1 - 4.2 6.2 14.2 0.053 12.5 4.6 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Acyltransferase PF01553.16 CCH60194.1 - 1.6e-11 43.7 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Peptidase_A4 PF01828.12 CCH60194.1 - 0.041 12.9 0.3 0.098 11.7 0.2 1.6 1 0 0 1 1 1 0 Peptidase A4 family Kinesin PF00225.18 CCH60195.1 - 4.3e-98 328.1 9.1 4.3e-98 328.1 6.3 3.1 2 1 0 3 3 3 1 Kinesin motor domain Metallophos PF00149.23 CCH60196.1 - 1.8e-36 125.4 0.1 2.7e-36 124.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CCH60196.1 - 2.3e-19 68.7 0.1 1.3e-15 56.8 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCH60196.1 - 1.2e-14 53.1 0.3 0.00016 21.1 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCH60196.1 - 7.4e-14 50.4 0.0 0.00065 19.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 CCH60196.1 - 3.3e-11 43.0 0.0 1e-08 35.0 0.0 2.7 1 1 0 1 1 1 1 PPP5 TPR repeat region TPR_16 PF13432.1 CCH60196.1 - 0.00093 19.8 0.0 0.63 10.7 0.0 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCH60196.1 - 0.0024 17.5 0.3 4.2 7.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCH60196.1 - 0.0028 17.7 0.0 0.047 13.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCH60196.1 - 0.0063 16.3 0.0 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CCH60196.1 - 0.011 16.0 0.0 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCH60196.1 - 0.018 14.9 0.0 2.3 8.1 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCH60196.1 - 0.022 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCH60196.1 - 0.046 14.3 0.0 8 7.4 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 CCH60196.1 - 0.22 11.4 0.6 0.68 9.8 0.1 2.0 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain EMP24_GP25L PF01105.19 CCH60198.1 - 8e-47 159.3 0.3 9.6e-47 159.0 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UPF0370 PF13980.1 CCH60198.1 - 0.26 11.1 1.2 0.59 9.9 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) WD40 PF00400.27 CCH60199.1 - 3.1e-18 64.8 2.4 4e-10 39.1 0.2 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 CCH60199.1 - 1.5e-06 28.0 0.5 0.0015 18.2 0.0 3.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CCH60199.1 - 0.00028 19.7 0.3 0.08 11.6 0.0 2.6 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCH60199.1 - 0.0017 16.7 0.0 0.0037 15.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF1623 PF07785.6 CCH60199.1 - 0.02 14.8 1.1 0.078 12.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) Fungal_trans PF04082.13 CCH60200.1 - 1.4e-08 33.9 0.8 3.2e-08 32.7 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH60200.1 - 0.00013 21.8 9.0 0.00022 21.0 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RecR PF02132.10 CCH60200.1 - 1.8 8.0 7.1 0.25 10.8 0.8 2.3 2 0 0 2 2 2 0 RecR protein E1-E2_ATPase PF00122.15 CCH60201.1 - 1.1e-58 197.9 2.6 1.1e-58 197.9 1.8 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCH60201.1 - 3.7e-39 134.1 13.1 3.7e-39 134.1 9.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCH60201.1 - 6.1e-25 88.9 0.0 1.4e-18 68.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH60201.1 - 3e-16 59.1 0.0 6.4e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCH60201.1 - 2.8e-11 43.9 0.0 7.7e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCH60201.1 - 3.5e-09 36.0 0.0 1.1e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCH60201.1 - 6.2e-05 22.7 0.3 0.00032 20.3 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NfeD PF01957.13 CCH60201.1 - 0.095 12.8 8.8 0.16 12.0 0.0 3.1 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3671 PF12420.3 CCH60201.1 - 0.26 11.2 6.9 0.064 13.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function tRNA_int_endo PF01974.12 CCH60202.1 - 6.2e-13 48.3 0.0 1.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain E1-E2_ATPase PF00122.15 CCH60203.1 - 9.3e-62 208.0 4.4 9.3e-62 208.0 3.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCH60203.1 - 1e-24 88.1 0.1 1.9e-24 87.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH60203.1 - 9.5e-17 61.7 0.0 2.5e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCH60203.1 - 1.3e-11 43.7 0.0 1.3e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCH60203.1 - 0.0021 17.6 0.1 0.0048 16.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH60203.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit PUF PF00806.14 CCH60204.1 - 1.8e-61 200.2 18.8 8.6e-09 34.4 0.0 9.2 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat Reg_prop PF07494.6 CCH60204.1 - 0.54 10.4 2.2 52 4.3 0.1 3.9 3 0 0 3 3 3 0 Two component regulator propeller Fungal_trans PF04082.13 CCH60205.1 - 2.7e-25 88.7 8.4 2.7e-25 88.7 5.8 3.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH60205.1 - 5.7e-10 38.9 13.2 1.1e-09 38.0 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 CCH60206.1 - 1.9e-179 596.7 30.6 2.2e-179 596.5 21.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Rsc14 PF08586.5 CCH60207.1 - 2e-30 105.2 3.1 2e-30 105.2 2.2 1.9 2 0 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit DUF2296 PF10058.4 CCH60207.1 - 0.012 15.3 0.2 0.055 13.2 0.1 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF4224 PF13986.1 CCH60207.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Proteasome PF00227.21 CCH60208.1 - 7.6e-45 152.5 0.0 1.1e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH60208.1 - 1.9e-15 55.8 0.1 3.4e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cullin_binding PF03556.10 CCH60208.1 - 0.06 13.4 0.0 0.17 12.0 0.0 1.8 2 1 0 2 2 2 0 Cullin binding DUF962 PF06127.6 CCH60209.1 - 2.7e-22 78.4 5.9 2e-21 75.7 4.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHD1 PF03983.7 CCH60210.1 - 8.3e-35 118.2 0.0 1.5e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 CCH60210.1 - 9.8e-34 114.5 5.0 5.1e-12 44.9 0.0 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 CCH60210.1 - 1.7e-32 110.7 7.0 2.4e-11 43.0 0.2 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 CCH60210.1 - 8.2e-27 92.4 0.0 1.9e-07 30.4 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 CCH60210.1 - 0.0044 17.1 2.5 3.3 7.9 0.0 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain DUF3104 PF11302.3 CCH60210.1 - 0.035 13.4 0.1 0.14 11.5 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF2459 PF09601.5 CCH60210.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) SpoVA PF03862.8 CCH60210.1 - 2.4 8.2 9.0 26 4.9 0.1 4.0 2 2 2 4 4 4 0 SpoVA protein WD40 PF00400.27 CCH60211.1 - 2.2e-45 150.9 15.1 6.4e-11 41.6 0.0 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat Hira PF07569.6 CCH60211.1 - 2.5e-15 56.2 0.9 7.2e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split HIRA_B PF09453.5 CCH60211.1 - 2e-08 33.5 0.2 6.6e-08 31.8 0.1 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 CCH60211.1 - 0.0002 20.9 0.0 6.2 6.5 0.0 4.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CCH60211.1 - 0.016 14.3 0.2 0.11 11.5 0.0 2.5 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal ATE_C PF04377.10 CCH60213.1 - 5.4e-42 142.8 5.0 1.1e-41 141.9 3.4 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CCH60213.1 - 6.6e-23 80.3 2.9 1.4e-22 79.2 1.6 1.8 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus CK_II_beta PF01214.13 CCH60214.1 - 1.4e-62 210.4 0.0 1.7e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CHD5 PF04420.9 CCH60215.1 - 6.2e-34 116.9 1.7 8.4e-34 116.5 1.2 1.1 1 0 0 1 1 1 1 CHD5-like protein DpnII PF04556.7 CCH60215.1 - 0.015 14.3 2.3 0.016 14.2 0.6 1.8 2 0 0 2 2 2 0 DpnII restriction endonuclease Rota_NSP3 PF01665.11 CCH60215.1 - 0.021 13.7 0.5 0.031 13.2 0.4 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 DASH_Dad2 PF08654.5 CCH60216.1 - 0.12 12.3 0.2 0.12 12.3 0.1 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad2 Astro_capsid PF03115.9 CCH60216.1 - 4.1 5.5 12.0 5.7 5.0 8.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Acyltransferase PF01553.16 CCH60217.1 - 1.8e-07 30.6 0.0 2.4e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Formyl_trans_N PF00551.14 CCH60218.1 - 1.8e-28 99.2 0.0 3.1e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CCH60218.1 - 0.0055 16.7 0.0 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain Cgr1 PF03879.9 CCH60219.1 - 7.8e-37 125.7 28.6 9e-37 125.5 19.8 1.0 1 0 0 1 1 1 1 Cgr1 family LppC PF04348.8 CCH60219.1 - 0.036 12.6 8.0 0.038 12.5 5.5 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein THOC7 PF05615.8 CCH60219.1 - 0.058 13.6 14.7 0.078 13.2 10.2 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 RICTOR_phospho PF14665.1 CCH60219.1 - 0.062 13.3 0.4 0.097 12.7 0.3 1.5 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site NDT80_PhoG PF05224.7 CCH60219.1 - 0.077 12.9 2.0 0.086 12.8 1.4 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DRY_EERY PF09750.4 CCH60219.1 - 0.27 11.3 7.4 0.34 11.0 5.1 1.3 1 0 0 1 1 1 0 Alternative splicing regulator CAF-1_p150 PF11600.3 CCH60219.1 - 0.32 10.3 25.4 0.36 10.1 17.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 CCH60219.1 - 0.33 10.7 10.4 0.35 10.6 7.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF342 PF03961.8 CCH60219.1 - 0.43 8.9 8.4 0.45 8.8 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PPR_2 PF13041.1 CCH60220.1 - 3.1e-13 49.4 6.6 2e-10 40.4 0.1 3.8 2 1 2 4 4 4 2 PPR repeat family PPR PF01535.15 CCH60220.1 - 3.8e-12 45.3 0.2 1.4e-06 27.8 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CCH60220.1 - 4.5e-09 35.8 3.5 0.00093 19.3 0.0 6.2 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCH60220.1 - 0.0003 20.2 0.0 0.011 15.2 0.0 2.8 2 0 0 2 2 2 1 PPR repeat Apc3 PF12895.2 CCH60220.1 - 0.46 10.6 6.3 0.4 10.8 0.0 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2838 PF10998.3 CCH60221.1 - 2.4e-43 146.5 12.0 2.4e-43 146.5 8.3 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Ribosomal_L7Ae PF01248.21 CCH60222.1 - 1.1e-24 85.6 0.1 1.3e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TBPIP PF07106.8 CCH60224.1 - 1.5e-22 79.9 11.3 2e-22 79.5 7.9 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SYCE1 PF15233.1 CCH60224.1 - 0.018 14.9 12.0 0.37 10.7 0.5 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Cep57_MT_bd PF06657.8 CCH60224.1 - 0.54 10.2 4.8 7 6.6 0.8 2.6 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GDPD PF03009.12 CCH60224.1 - 0.64 9.4 5.1 4.3 6.7 1.3 2.0 1 1 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Spc24 PF08286.6 CCH60224.1 - 2.8 7.6 12.2 0.59 9.8 0.5 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 SNARE PF05739.14 CCH60225.1 - 0.016 14.8 3.5 0.016 14.8 2.4 3.5 3 0 0 3 3 3 0 SNARE domain DUF4490 PF14892.1 CCH60225.1 - 0.26 10.9 8.8 0.056 13.0 2.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4490) Isochorismatase PF00857.15 CCH60227.1 - 2.2e-26 92.8 0.0 2.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Gly_transf_sug PF04488.10 CCH60228.1 - 2.2e-13 50.4 0.9 7.4e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TFIIS_M PF07500.9 CCH60229.1 - 1.1e-26 93.1 0.3 1.1e-26 93.1 0.2 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CCH60229.1 - 1.9e-17 62.6 6.3 3.1e-17 61.8 4.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CCH60229.1 - 1.7e-13 49.8 1.7 1.7e-13 49.8 1.2 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ribosomal_S27 PF01599.14 CCH60229.1 - 0.22 11.4 2.6 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a Baculo_LEF5_C PF11792.3 CCH60229.1 - 0.37 10.1 2.1 2.4 7.6 1.6 2.3 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.2 CCH60229.1 - 1.5 8.6 5.4 4.8 7.0 3.8 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RRM_1 PF00076.17 CCH60230.1 - 3e-19 68.3 0.0 5.2e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60230.1 - 1.9e-14 53.3 0.0 4.3e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60230.1 - 5.8e-10 38.8 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 CCH60230.1 - 3.2e-05 23.0 0.5 7.7e-05 21.8 0.3 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 CCH60230.1 - 0.00089 19.2 0.1 0.0024 17.9 0.1 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF2_hinge PF14327.1 CCH60231.1 - 1.5e-22 79.4 2.0 1.5e-22 79.4 1.4 2.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 CCH60231.1 - 3.4e-05 23.0 0.8 0.0001 21.4 0.6 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 CCH60231.1 - 0.0006 19.3 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AcetDehyd-dimer PF09290.6 CCH60231.1 - 0.067 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF2196 PF09962.4 CCH60231.1 - 0.18 11.6 0.2 1.5 8.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2196) GWT1 PF06423.7 CCH60232.1 - 0.013 15.6 0.6 0.016 15.3 0.4 1.2 1 0 0 1 1 1 0 GWT1 DUF4384 PF14326.1 CCH60232.1 - 0.026 14.3 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) RNase_PH PF01138.16 CCH60233.1 - 6.1e-19 68.6 0.4 7.9e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RRM_1 PF00076.17 CCH60234.1 - 5e-45 151.0 0.0 1.3e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60234.1 - 2.8e-30 104.1 0.0 9.5e-16 57.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60234.1 - 1.9e-20 72.4 0.0 5.9e-12 45.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCH60234.1 - 0.1 12.3 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MIF4G PF02854.14 CCH60236.1 - 1.4e-43 148.7 0.0 1.4e-43 148.7 0.0 2.6 3 1 0 3 3 3 1 MIF4G domain eIF_4G1 PF12152.3 CCH60236.1 - 1e-21 76.5 0.2 5e-21 74.3 0.1 2.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Cys_Met_Meta_PP PF01053.15 CCH60237.1 - 1.3e-142 474.7 0.0 1.4e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCH60237.1 - 1.2e-11 44.3 0.1 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CCH60237.1 - 3.3e-08 32.8 0.0 5.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCH60237.1 - 1.7e-07 30.3 0.1 2.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCH60237.1 - 4.3e-06 26.0 0.0 8.1e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CCH60237.1 - 0.00099 17.5 0.0 0.0015 16.9 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CCH60237.1 - 0.01 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein Phg_2220_C PF09524.5 CCH60237.1 - 0.085 12.8 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) CPSase_L_D2 PF02786.12 CCH60237.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain FlxA PF14282.1 CCH60238.1 - 0.64 9.9 11.5 0.06 13.3 4.3 1.9 2 0 0 2 2 2 0 FlxA-like protein TSC22 PF01166.13 CCH60238.1 - 1.9 8.4 6.0 0.54 10.2 0.6 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF3573 PF12097.3 CCH60238.1 - 5.3 5.5 9.8 0.14 10.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) CBF PF03914.12 CCH60239.1 - 9.6e-45 151.9 0.5 9.6e-45 151.9 0.3 2.5 2 0 0 2 2 2 1 CBF/Mak21 family GNAT_acetyltran PF12746.2 CCH60239.1 - 0.019 13.7 0.4 0.038 12.8 0.2 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase Asn_synthase PF00733.16 CCH60240.1 - 2.7e-70 236.8 0.0 3.8e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCH60240.1 - 2e-34 117.9 0.0 3.4e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCH60240.1 - 1.8e-28 99.1 0.0 1.2e-27 96.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCH60240.1 - 2.6e-09 36.6 0.0 4.8e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CCH60240.1 - 3.5e-05 22.6 0.0 1.7 7.2 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II QueC PF06508.8 CCH60240.1 - 0.0048 16.2 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 CCH60240.1 - 0.019 13.8 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Sulfate_transp PF00916.15 CCH60241.1 - 2.4e-51 174.4 12.6 5.6e-51 173.1 8.7 1.7 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 CCH60241.1 - 2e-14 53.0 1.5 3.6e-14 52.1 1.0 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 CCH60241.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2305 PF10230.4 CCH60242.1 - 3.7e-70 236.3 0.2 4.2e-70 236.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CCH60242.1 - 2.5e-06 27.5 0.0 3.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 CCH60242.1 - 1.3e-05 24.1 1.8 0.01 14.6 0.7 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 CCH60242.1 - 0.00068 19.2 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCH60242.1 - 0.00073 19.3 0.0 0.00081 19.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 CCH60242.1 - 0.023 13.6 0.5 0.83 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 CCH60242.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 CCH60242.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF3089 PF11288.3 CCH60242.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Utp8 PF10395.4 CCH60243.1 - 5.3e-195 649.6 29.0 6e-195 649.4 20.1 1.0 1 0 0 1 1 1 1 Utp8 family Cytochrom_C_2 PF01322.15 CCH60244.1 - 0.23 12.0 2.3 6.1 7.4 0.2 2.8 2 1 1 3 3 3 0 Cytochrome C' MARVEL PF01284.18 CCH60246.1 - 1.8e-25 89.4 6.5 2.2e-25 89.1 4.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain UQ_con PF00179.21 CCH60247.1 - 4.9e-35 120.0 1.2 5.5e-35 119.8 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH60247.1 - 2.4e-05 24.1 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCH60247.1 - 0.0045 16.8 1.7 0.0059 16.4 0.8 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CCH60247.1 - 0.0075 15.9 0.6 0.012 15.2 0.4 1.3 1 0 0 1 1 1 1 UEV domain Tmemb_170 PF10190.4 CCH60249.1 - 0.0079 16.2 3.9 0.0096 15.9 2.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF3816 PF12822.2 CCH60249.1 - 1.2 8.9 10.8 1.7 8.5 7.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF4282 PF14110.1 CCH60249.1 - 9.8 6.4 8.5 33 4.7 5.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) SH3_1 PF00018.23 CCH60250.1 - 1.7e-13 49.7 0.0 3.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH60250.1 - 5e-13 48.4 0.0 9e-13 47.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH60250.1 - 1.5e-09 37.2 0.0 2.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAT1 PF09770.4 CCH60250.1 - 0.2 9.8 19.4 0.24 9.6 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2076 PF09849.4 CCH60250.1 - 0.55 10.2 14.5 0.12 12.4 7.6 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2486 PF10667.4 CCH60250.1 - 2.4 8.6 6.8 1.3 9.4 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) Extensin_2 PF04554.8 CCH60250.1 - 3.4 7.5 18.2 10 6.0 12.6 1.9 1 1 0 1 1 1 0 Extensin-like region DUF946 PF06101.6 CCH60251.1 - 4.3e-07 28.3 1.6 5.3e-07 28.0 0.4 1.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) HCMVantigenic_N PF12154.3 CCH60251.1 - 0.093 12.6 0.6 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV SKN1 PF03935.10 CCH60253.1 - 2.4e-250 830.8 5.0 2.4e-250 830.8 3.5 1.8 2 0 0 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) DUF1438 PF07270.6 CCH60253.1 - 0.024 14.5 2.3 3.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1438) Apc4 PF12896.2 CCH60254.1 - 1.7e-23 83.0 1.4 1.7e-23 83.0 1.0 2.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 4 PHD PF00628.24 CCH60255.1 - 0.012 15.2 4.2 0.039 13.6 2.9 1.8 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.20 CCH60256.1 - 1e-72 244.4 1.0 6e-72 241.9 0.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60256.1 - 1.3e-41 142.3 0.4 4.5e-40 137.3 0.0 2.3 1 1 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.14 CCH60256.1 - 1.3e-19 69.3 0.0 2.3e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CCH60256.1 - 2.6e-07 29.9 0.0 5.7e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH60256.1 - 3.5e-05 22.9 0.1 8.5e-05 21.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH60256.1 - 0.0049 16.6 0.0 0.017 14.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Transp_cyt_pur PF02133.10 CCH60258.1 - 1e-85 287.9 35.9 1.2e-85 287.6 24.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.21 CCH60259.1 - 2e-51 174.9 0.0 2.7e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CCH60259.1 - 8.3e-25 86.9 0.1 1.5e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CCH60259.1 - 0.058 12.3 0.1 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Macoilin PF09726.4 CCH60260.1 - 0.53 8.4 56.6 0.063 11.5 20.8 2.4 2 0 0 2 2 2 0 Transmembrane protein Vhr1 PF04001.8 CCH60261.1 - 9e-50 166.5 2.0 2.4e-49 165.2 1.4 1.8 1 0 0 1 1 1 1 Transcription factor Vhr1 ICL PF00463.16 CCH60262.1 - 8.1e-251 832.7 2.4 9.8e-251 832.4 1.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCH60262.1 - 7.7e-10 38.3 0.3 2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2578 PF10843.3 CCH60263.1 - 4e-56 189.7 12.6 5e-56 189.4 8.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) RRM_1 PF00076.17 CCH60264.1 - 6.4e-14 51.3 0.8 1.1e-11 44.2 0.5 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CCH60264.1 - 1.2e-11 44.8 1.5 1.2e-11 44.8 1.0 2.1 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 CCH60264.1 - 9.5e-10 38.3 0.3 1.2e-08 34.7 0.2 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60264.1 - 0.00012 21.8 1.5 0.0011 18.7 1.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF619 PF04768.8 CCH60265.1 - 3.4e-53 179.5 0.7 6.8e-53 178.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CCH60265.1 - 3.4e-30 104.8 0.0 7.8e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CCH60265.1 - 9.7e-20 71.1 0.0 2e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 CCH60265.1 - 8e-11 42.1 0.0 1.8e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 CCH60265.1 - 0.0025 17.7 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.9 CCH60266.1 - 7.3e-51 172.1 0.0 8.2e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Sigma70_r4_2 PF08281.7 CCH60266.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 RolB_RolC PF02027.12 CCH60266.1 - 0.025 13.7 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 RolB/RolC glucosidase family Ran_BP1 PF00638.13 CCH60267.1 - 4e-35 120.5 0.8 4e-35 120.5 0.5 2.2 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 CCH60267.1 - 4e-05 23.2 0.0 8.2e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 WH1 domain Methyltransf_31 PF13847.1 CCH60268.1 - 3.3e-26 91.7 0.1 5.1e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH60268.1 - 1.9e-18 67.0 0.0 3.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH60268.1 - 8.8e-09 35.7 0.0 1.6e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH60268.1 - 1.2e-07 32.0 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH60268.1 - 2.1e-06 27.7 0.0 4.9e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH60268.1 - 3.2e-06 27.4 0.0 5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH60268.1 - 0.00012 21.4 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCH60268.1 - 0.00012 21.7 0.0 0.00024 20.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCH60268.1 - 0.00022 20.4 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 CCH60268.1 - 0.00036 20.2 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH60268.1 - 0.0042 16.2 0.1 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 CCH60268.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 CCH60268.1 - 0.072 12.2 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 CCH60268.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 CCH60268.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Fis1_TPR_C PF14853.1 CCH60269.1 - 1.9e-21 75.6 0.7 3.2e-21 74.9 0.5 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CCH60269.1 - 4.6e-16 57.8 0.0 7.8e-16 57.0 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 CCH60269.1 - 0.00022 20.8 1.2 0.00048 19.8 0.5 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCH60269.1 - 0.032 14.3 0.2 0.049 13.7 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CCH60269.1 - 0.039 14.2 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCH60269.1 - 0.042 14.4 0.2 0.2 12.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat VPEP PF07589.6 CCH60269.1 - 0.46 10.4 1.8 1 9.3 1.3 1.7 1 0 0 1 1 1 0 PEP-CTERM motif Ribonuc_red_lgC PF02867.10 CCH60270.1 - 1e-213 710.8 0.0 2.1e-213 709.7 0.0 1.5 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCH60270.1 - 7.4e-25 86.5 0.1 2e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCH60270.1 - 6.5e-15 55.3 0.0 2.4e-14 53.4 0.0 2.1 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 CCH60270.1 - 0.025 12.6 0.0 0.041 11.9 0.0 1.3 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DUF1054 PF06335.7 CCH60270.1 - 0.051 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Sec6 PF06046.8 CCH60271.1 - 7.3e-163 542.6 14.7 1.1e-162 542.0 10.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Tctex-1 PF03645.8 CCH60272.1 - 5.5e-08 32.5 0.0 7.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF1842 PF08896.5 CCH60272.1 - 0.053 13.2 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) DUF202 PF02656.10 CCH60273.1 - 3.2e-14 52.9 3.3 3.2e-14 52.9 2.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4234 PF14018.1 CCH60273.1 - 0.082 12.6 0.3 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) LHC PF00556.15 CCH60273.1 - 0.13 12.0 0.3 0.13 12.0 0.2 2.2 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF2207 PF09972.4 CCH60273.1 - 1.3 7.5 5.1 2.4 6.6 3.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_S24e PF01282.14 CCH60274.1 - 7.6e-34 115.3 0.1 1.2e-33 114.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Y_phosphatase PF00102.22 CCH60275.1 - 1.9e-42 145.2 7.6 2e-36 125.5 1.8 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 CCH60275.1 - 4e-08 33.5 0.0 1.1e-06 28.9 0.0 2.8 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 CCH60275.1 - 0.018 14.6 4.4 0.018 14.5 0.0 3.5 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain MAM33 PF02330.11 CCH60276.1 - 3.2e-44 151.1 15.3 4e-44 150.8 10.6 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein PPR_2 PF13041.1 CCH60277.1 - 1.6e-13 50.4 0.2 8.9e-10 38.4 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family PCI PF01399.22 CCH60278.1 - 0.004 17.4 2.4 0.014 15.6 0.1 2.7 2 1 0 2 2 2 1 PCI domain HIT PF01230.18 CCH60279.1 - 1.1e-25 90.0 0.2 1.5e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCH60279.1 - 1.2e-11 44.8 0.2 1.7e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCH60279.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 AAA PF00004.24 CCH60280.1 - 2e-99 328.9 0.0 2.5e-48 163.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCH60280.1 - 3.8e-18 65.2 0.2 1.1e-17 63.7 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CCH60280.1 - 1.1e-14 54.7 0.3 6.3e-07 29.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCH60280.1 - 2.3e-13 50.5 0.0 4.8e-05 23.4 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 CCH60280.1 - 3.1e-13 49.3 0.0 2.2e-05 23.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCH60280.1 - 2.5e-12 47.6 0.1 0.00015 22.5 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CCH60280.1 - 4.1e-12 45.9 1.0 4.3e-06 26.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCH60280.1 - 3.5e-11 43.3 4.0 0.00017 21.7 0.1 4.5 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.1 CCH60280.1 - 7e-11 42.1 0.0 2.7e-05 24.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCH60280.1 - 1.6e-09 36.9 2.7 0.00093 18.0 0.0 3.3 3 0 0 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 CCH60280.1 - 1.9e-09 37.4 0.0 0.00071 19.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CCH60280.1 - 2.7e-08 33.4 0.9 0.0095 15.6 0.2 3.1 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 CCH60280.1 - 3.2e-08 33.0 0.0 8.9e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 CCH60280.1 - 3.3e-08 33.1 9.1 0.035 13.5 0.1 4.4 2 2 2 4 4 4 3 AAA domain IstB_IS21 PF01695.12 CCH60280.1 - 4.2e-08 32.8 0.1 0.0075 15.6 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 CCH60280.1 - 8.8e-08 32.2 0.0 0.0081 16.3 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.1 CCH60280.1 - 1.8e-07 31.4 1.5 0.054 13.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.1 CCH60280.1 - 3.7e-07 29.9 0.1 0.034 13.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 CCH60280.1 - 4.3e-07 29.2 2.8 0.079 12.0 0.0 3.9 2 2 2 4 4 4 2 KaiC ResIII PF04851.10 CCH60280.1 - 5.5e-07 29.6 0.6 0.002 18.0 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 CCH60280.1 - 1.1e-06 27.9 0.0 0.033 13.2 0.0 2.9 2 1 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 CCH60280.1 - 1.1e-06 27.9 0.2 0.022 13.9 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCH60280.1 - 1.9e-06 27.9 0.1 0.064 13.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CCH60280.1 - 4.9e-06 26.1 0.1 0.05 13.0 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_11 PF13086.1 CCH60280.1 - 9.7e-06 25.3 1.6 0.17 11.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CCH60280.1 - 1.3e-05 25.2 0.0 0.051 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 CCH60280.1 - 2.4e-05 23.6 0.5 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 CCH60280.1 - 2.8e-05 23.1 0.1 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CCH60280.1 - 3.4e-05 23.5 0.0 0.05 13.2 0.0 2.9 2 0 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.7 CCH60280.1 - 4.1e-05 23.2 0.2 1.6 8.3 0.0 3.9 4 0 0 4 4 4 2 NACHT domain DUF2075 PF09848.4 CCH60280.1 - 5.7e-05 22.2 0.0 0.18 10.7 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CCH60280.1 - 6e-05 23.3 3.0 0.076 13.3 0.0 4.2 5 1 0 5 5 2 1 ABC transporter Vps4_C PF09336.5 CCH60280.1 - 8e-05 22.4 0.3 0.0009 19.0 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 CCH60280.1 - 8.2e-05 22.2 0.0 0.52 9.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CCH60280.1 - 0.00013 20.9 0.0 0.13 11.1 0.0 2.9 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 CCH60280.1 - 0.00041 19.9 0.0 0.91 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCH60280.1 - 0.00044 20.0 6.5 1.9 8.1 0.0 4.0 3 2 2 5 5 4 2 Archaeal ATPase NB-ARC PF00931.17 CCH60280.1 - 0.0022 16.9 0.2 1.8 7.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain IPT PF01745.11 CCH60280.1 - 0.0039 16.3 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase NTPase_1 PF03266.10 CCH60280.1 - 0.0041 16.8 1.4 3.5 7.3 0.0 4.1 4 0 0 4 4 4 0 NTPase T2SE PF00437.15 CCH60280.1 - 0.034 13.0 0.0 3.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 CCH60280.1 - 0.07 12.7 0.1 7.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 CCH60280.1 - 0.074 12.0 3.4 1.7 7.5 0.0 3.4 3 2 1 4 4 3 0 KAP family P-loop domain Zot PF05707.7 CCH60280.1 - 0.094 12.1 3.2 3.6 7.0 0.0 3.7 3 1 0 3 3 2 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 CCH60280.1 - 0.12 12.6 4.9 21 5.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 CCH60280.1 - 0.14 11.6 0.1 16 4.9 0.0 2.9 4 0 0 4 4 2 0 Viral (Superfamily 1) RNA helicase SKI PF01202.17 CCH60280.1 - 0.17 11.7 2.6 4.7 7.0 0.0 3.1 3 0 0 3 3 2 0 Shikimate kinase FKBP_N PF01346.13 CCH60280.1 - 0.19 11.7 8.6 0.028 14.4 1.7 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Cyclin_N PF00134.18 CCH60281.1 - 5.1e-16 58.3 0.1 9.3e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCH60281.1 - 3.6e-09 37.1 0.1 3.6e-09 37.1 0.1 2.1 2 1 0 2 2 2 1 Cyclin CDP-OH_P_transf PF01066.16 CCH60282.1 - 5.1e-11 42.7 3.6 9.3e-11 41.9 2.5 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase E1-E2_ATPase PF00122.15 CCH60282.1 - 0.11 11.5 0.2 3.5 6.5 0.0 2.2 2 0 0 2 2 2 0 E1-E2 ATPase Clathrin PF00637.15 CCH60283.1 - 3.1e-190 623.3 59.1 9.5e-33 112.8 0.1 9.0 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CCH60283.1 - 4.2e-24 84.2 0.1 2e-23 82.0 0.1 2.3 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 CCH60283.1 - 8.2e-18 63.4 3.6 0.0017 18.4 0.1 5.9 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.5 CCH60283.1 - 9.7e-08 30.8 2.0 5e-07 28.6 0.0 2.9 3 0 0 3 3 3 1 Clathrin, heavy-chain linker TPR_19 PF14559.1 CCH60283.1 - 2.9 8.2 7.4 70 3.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.1 CCH60284.1 - 1.8e-07 31.0 16.5 1.1e-05 25.4 3.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCH60284.1 - 2.7e-06 27.3 15.7 0.0023 18.1 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH60284.1 - 0.00011 22.2 16.6 0.0023 18.1 0.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCH60284.1 - 0.13 12.4 8.0 0.19 11.9 1.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding LSM PF01423.17 CCH60285.1 - 4e-18 64.7 0.8 8.1e-18 63.7 0.5 1.5 1 0 0 1 1 1 1 LSM domain Filo_glycop PF01611.11 CCH60285.1 - 0.068 11.9 4.3 0.078 11.7 3.0 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein FAM177 PF14774.1 CCH60285.1 - 0.25 11.2 3.1 0.42 10.5 2.1 1.3 1 0 0 1 1 1 0 FAM177 family Menin PF05053.8 CCH60285.1 - 0.27 9.3 3.9 0.31 9.1 2.7 1.1 1 0 0 1 1 1 0 Menin CHZ PF09649.5 CCH60286.1 - 6.3e-15 54.1 1.7 6.3e-15 54.1 1.2 2.7 3 0 0 3 3 3 1 Histone chaperone domain CHZ Spc42p PF11544.3 CCH60286.1 - 0.00027 20.8 4.0 0.00027 20.8 2.8 2.3 1 1 1 2 2 2 1 Spindle pole body component Spc42p Ras PF00071.17 CCH60287.1 - 6.7e-61 204.4 0.1 8e-61 204.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH60287.1 - 6.6e-20 71.7 0.0 1.2e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH60287.1 - 4.6e-13 48.7 0.0 6.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCH60287.1 - 4.2e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CCH60287.1 - 5e-06 25.8 0.1 9.6e-06 24.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 CCH60287.1 - 0.00015 21.2 0.1 0.00043 19.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCH60287.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CCH60287.1 - 0.0021 17.2 0.2 0.0046 16.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 CCH60287.1 - 0.007 15.3 0.0 0.0095 14.9 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain PduV-EutP PF10662.4 CCH60287.1 - 0.0075 15.7 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CCH60287.1 - 0.01 15.0 0.1 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CCH60287.1 - 0.013 15.4 0.7 0.24 11.3 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCH60287.1 - 0.018 15.2 0.1 0.036 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CCH60287.1 - 0.035 13.1 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin TraG_N PF07916.6 CCH60287.1 - 0.054 11.9 1.9 0.069 11.5 1.3 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region FeoB_N PF02421.13 CCH60287.1 - 0.088 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 CCH60287.1 - 0.12 12.6 2.6 0.3 11.3 1.7 1.9 1 1 0 1 1 1 0 ABC transporter CAF-1_p150 PF11600.3 CCH60287.1 - 2.6 7.3 4.8 3.8 6.8 3.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMPIT PF07851.8 CCH60289.1 - 2.2 7.2 5.9 5 6.1 4.1 1.5 1 0 0 1 1 1 0 TMPIT-like protein ATP_bind_3 PF01171.15 CCH60290.1 - 1.2e-19 70.5 0.0 3.3e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CCH60290.1 - 2.2e-05 24.7 0.0 7.4e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 CCH60290.1 - 0.0005 18.7 0.9 0.0013 17.3 0.0 2.0 2 1 0 2 2 2 1 tRNA methyl transferase Ribosomal_S14 PF00253.16 CCH60290.1 - 0.042 13.2 0.4 0.042 13.2 0.3 3.4 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e NAD_synthase PF02540.12 CCH60290.1 - 0.067 12.0 0.2 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD synthase Asn_synthase PF00733.16 CCH60290.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase TF_Zn_Ribbon PF08271.7 CCH60290.1 - 0.71 9.2 8.7 0.97 8.8 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding Cyclin PF08613.6 CCH60291.1 - 6e-06 26.7 0.1 6e-06 26.7 0.1 2.6 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CCH60291.1 - 0.0049 16.4 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain Kinesin PF00225.18 CCH60292.1 - 1.7e-113 378.7 6.9 3.7e-113 377.6 4.8 1.6 1 0 0 1 1 1 1 Kinesin motor domain BolA PF01722.13 CCH60293.1 - 3.4e-18 65.3 0.0 4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 CCH60294.1 - 5.6e-60 202.9 0.0 6.7e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) TIM PF00121.13 CCH60294.1 - 0.0062 15.6 0.0 0.062 12.3 0.0 2.3 3 0 0 3 3 3 1 Triosephosphate isomerase HMA PF00403.21 CCH60296.1 - 0.28 11.3 1.1 0.9 9.7 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain WD40 PF00400.27 CCH60297.1 - 2e-12 46.4 6.2 2e-05 24.2 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.1 CCH60297.1 - 0.051 13.8 0.1 0.35 11.2 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain NMT PF01233.14 CCH60298.1 - 3e-85 283.8 0.2 5.8e-85 282.8 0.2 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CCH60298.1 - 4.8e-76 254.4 2.9 4.9e-76 254.3 0.4 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CCH60298.1 - 7.7e-07 29.0 0.0 1.2e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCH60298.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3602 PF12223.3 CCH60300.1 - 3.8e-19 68.8 6.8 1.8e-11 44.2 0.0 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) Metallophos_C PF14008.1 CCH60300.1 - 0.08 13.0 0.8 19 5.4 0.0 2.9 3 0 0 3 3 3 0 Iron/zinc purple acid phosphatase-like protein C eIF3_subunit PF08597.5 CCH60301.1 - 2.5e-55 187.7 15.4 2.9e-55 187.5 10.7 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit G_glu_transpept PF01019.16 CCH60302.1 - 0.033 12.6 1.6 0.043 12.3 1.1 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase PALP PF00291.20 CCH60303.1 - 2.4e-72 243.7 0.2 3e-72 243.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CCH60303.1 - 1.4e-38 130.3 0.1 3e-25 87.6 0.0 3.3 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.20 CCH60304.1 - 2.4e-32 111.8 0.4 3.9e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH60304.1 - 0.021 14.7 0.2 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Anticodon binding domain Tmemb_55A PF09788.4 CCH60304.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A Sec61_beta PF03911.11 CCH60305.1 - 1.9e-11 43.5 1.6 2.3e-11 43.2 1.1 1.2 1 0 0 1 1 1 1 Sec61beta family Tir_receptor_N PF07490.6 CCH60305.1 - 0.027 14.0 0.0 0.029 13.9 0.0 1.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus MOZ_SAS PF01853.13 CCH60306.1 - 6.6e-72 240.7 0.0 9.4e-72 240.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_1 PF00583.19 CCH60306.1 - 0.13 12.3 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Myb_DNA-bind_6 PF13921.1 CCH60307.1 - 1.1e-09 38.2 3.2 9.3e-09 35.2 0.3 3.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCH60307.1 - 4.8e-08 32.9 2.4 3.5e-05 23.7 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain TatD_DNase PF01026.16 CCH60308.1 - 2.6e-37 128.4 0.0 4.1e-37 127.7 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase TatD_DNase PF01026.16 CCH60309.1 - 2.2e-29 102.4 0.0 2.5e-28 98.9 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase Hydrolase_3 PF08282.7 CCH60309.1 - 0.076 12.5 1.7 0.48 9.9 0.0 2.7 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase PP2C PF00481.16 CCH60310.1 - 1.1e-77 260.9 0.2 1.7e-77 260.2 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SEP PF08059.8 CCH60311.1 - 8.4e-25 86.8 2.4 1.2e-24 86.4 0.2 2.4 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 CCH60311.1 - 1e-16 60.7 0.1 2.2e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCH60311.1 - 3.1e-05 23.4 0.3 7.3e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain DUF2935 PF11155.3 CCH60312.1 - 0.41 10.7 3.0 0.56 10.2 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) RICTOR_N PF14664.1 CCH60313.1 - 1.4e-91 306.8 14.9 3.1e-91 305.7 10.3 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CCH60313.1 - 1.4e-74 249.8 2.2 1.4e-74 249.8 1.6 3.5 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 CCH60313.1 - 8.4e-28 96.1 0.6 1.1e-26 92.5 0.2 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 CCH60313.1 - 4e-27 94.4 5.5 7.4e-27 93.5 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sel1 PF08238.7 CCH60315.1 - 6.7e-41 137.8 17.0 4.4e-08 33.5 1.4 7.4 7 0 0 7 7 7 7 Sel1 repeat PLDc_2 PF13091.1 CCH60315.1 - 0.0082 15.8 0.3 0.089 12.5 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain Sel1 PF08238.7 CCH60316.1 - 1.3e-39 133.7 13.6 2.1e-07 31.3 1.0 7.6 7 0 0 7 7 7 7 Sel1 repeat ACCA PF03255.9 CCH60317.1 - 0.072 12.6 2.1 0.13 11.7 1.3 1.6 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Fijivirus_P9-2 PF06837.6 CCH60317.1 - 2.3 7.3 7.9 0.7 8.9 0.5 2.2 1 1 1 2 2 2 0 Fijivirus P9-2 protein V_ATPase_I PF01496.14 CCH60317.1 - 2.3 5.9 8.7 3.1 5.5 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ApbA PF02558.11 CCH60318.1 - 2.8e-28 98.2 0.0 4.2e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CCH60318.1 - 3.3e-23 82.0 0.0 4.8e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 CCH60318.1 - 0.00079 19.1 0.0 0.0021 17.8 0.0 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Citrate_synt PF00285.16 CCH60319.1 - 5.1e-93 311.6 0.0 6e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 CCH60319.1 - 0.047 12.3 0.1 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 DUF1921 PF09081.5 CCH60319.1 - 0.12 12.4 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1921) MmgE_PrpD PF03972.9 CCH60320.1 - 2.2e-156 520.5 0.0 2.6e-156 520.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nic96 PF04097.9 CCH60321.1 - 2.3e-163 544.6 11.1 3e-163 544.2 7.7 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Peptidase_M24 PF00557.19 CCH60322.1 - 3e-57 193.5 0.0 3.9e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCH60322.1 - 2.4e-24 85.2 0.0 8.5e-24 83.4 0.0 2.0 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain Sulfate_transp PF00916.15 CCH60323.1 - 3.7e-53 180.3 9.4 3.7e-53 180.3 6.5 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCH60323.1 - 7.6e-27 92.8 4.4 2.3e-26 91.2 3.1 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCH60323.1 - 1.2e-14 53.7 0.0 2.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCH60323.1 - 0.25 11.4 0.0 0.7 9.9 0.0 1.7 1 1 0 1 1 1 0 STAS domain TFIIA PF03153.8 CCH60324.1 - 0.0017 18.3 23.7 0.0022 17.9 16.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.3 CCH60324.1 - 0.0027 16.8 9.1 0.0037 16.3 6.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) VID27 PF08553.5 CCH60324.1 - 0.0027 16.0 18.2 0.0035 15.6 12.6 1.2 1 0 0 1 1 1 1 VID27 cytoplasmic protein Mpp10 PF04006.7 CCH60324.1 - 0.0044 15.4 17.8 0.004 15.5 12.4 1.2 1 0 0 1 1 1 1 Mpp10 protein Astro_capsid PF03115.9 CCH60324.1 - 0.063 11.5 10.6 0.082 11.1 7.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 CCH60324.1 - 0.087 12.1 16.2 0.12 11.7 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 CCH60324.1 - 0.13 11.4 13.9 0.15 11.2 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TAP42 PF04177.7 CCH60324.1 - 0.55 9.1 18.7 1.2 7.9 13.0 1.6 1 1 0 1 1 1 0 TAP42-like family eIF-3c_N PF05470.7 CCH60324.1 - 2 6.3 13.2 2.2 6.2 9.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Paf1 PF03985.8 CCH60324.1 - 2.1 7.0 21.7 3.1 6.4 15.0 1.3 1 0 0 1 1 1 0 Paf1 RNA_pol_Rpc4 PF05132.9 CCH60324.1 - 2.8 7.9 4.8 5.1 7.0 3.3 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Trypan_PARP PF05887.6 CCH60324.1 - 8.9 6.1 23.9 13 5.5 16.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rad21_Rec8_N PF04825.8 CCH60325.1 - 5.9e-16 58.4 0.1 2e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rrp15p PF07890.7 CCH60326.1 - 1.5e-29 102.6 12.0 1.5e-29 102.6 8.3 2.6 2 1 0 2 2 2 1 Rrp15p Glyco_hydro_63 PF03200.11 CCH60326.1 - 0.0088 13.9 0.4 0.013 13.4 0.3 1.2 1 0 0 1 1 1 1 Mannosyl oligosaccharide glucosidase PAS_2 PF08446.6 CCH60326.1 - 0.073 13.5 0.2 0.25 11.8 0.1 1.9 1 1 0 1 1 1 0 PAS fold Kinesin PF00225.18 CCH60327.1 - 2.3e-98 329.0 5.6 4.5e-98 328.0 3.9 1.5 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_A17 PF05380.8 CCH60327.1 - 0.093 12.5 1.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Pao retrotransposon peptidase LRR_4 PF12799.2 CCH60327.1 - 0.21 11.2 5.2 0.31 10.6 1.1 3.4 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Acyltransferase PF01553.16 CCH60328.1 - 6e-15 54.8 0.0 1.3e-14 53.7 0.0 1.5 2 0 0 2 2 2 1 Acyltransferase Acyltransferase PF01553.16 CCH60329.1 - 0.042 13.2 0.0 0.16 11.4 0.0 1.9 1 1 0 1 1 1 0 Acyltransferase DUF2132 PF09905.4 CCH60329.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) WD40 PF00400.27 CCH60331.1 - 6.8e-22 76.4 4.8 3.7e-07 29.7 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M32 PF02074.10 CCH60331.1 - 0.26 9.8 4.0 0.38 9.3 2.8 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF3639 PF12341.3 CCH60332.1 - 4.7e-10 39.2 1.5 6.4e-10 38.8 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) COG2 PF06148.6 CCH60333.1 - 9.1e-07 28.8 4.4 2.4e-06 27.4 3.0 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 CCH60333.1 - 0.0065 16.1 0.2 0.0065 16.1 0.2 2.8 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF4208 PF13907.1 CCH60333.1 - 0.22 11.7 2.8 0.2 11.9 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Tom5 PF10642.4 CCH60334.1 - 5.2e-20 70.8 0.2 5.5e-20 70.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 CCH60335.1 - 1.6e-13 49.9 0.2 7.6e-13 47.7 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.6 CCH60335.1 - 0.0046 16.7 0.8 0.0046 16.7 0.6 2.2 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Ribosom_S12_S23 PF00164.20 CCH60336.1 - 2.5e-40 136.6 0.5 3e-40 136.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.19 CCH60337.1 - 3.6e-08 33.3 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCH60337.1 - 3.8e-06 26.5 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 CCH60337.1 - 0.0025 17.7 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCH60337.1 - 0.0029 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCH60337.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Hen1_L PF12623.2 CCH60337.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Aldo_ket_red PF00248.16 CCH60338.1 - 3e-41 141.1 0.0 3.4e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FlaC_arch PF05377.6 CCH60338.1 - 0.096 12.6 0.2 26 4.8 0.0 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) LETM1 PF07766.8 CCH60339.1 - 1.2e-91 306.5 3.7 1.7e-91 305.9 2.6 1.2 1 0 0 1 1 1 1 LETM1-like protein GPAT_N PF14829.1 CCH60339.1 - 0.016 14.8 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal ACOX PF01756.14 CCH60339.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA oxidase RNA_pol_3_Rpc31 PF11705.3 CCH60339.1 - 8.5 6.2 14.8 9.7 6.0 0.2 3.0 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Ctr PF04145.10 CCH60340.1 - 1.3e-24 86.9 2.5 1.3e-24 86.9 1.7 2.0 2 0 0 2 2 2 1 Ctr copper transporter family DUF4229 PF14012.1 CCH60340.1 - 0.018 14.9 1.8 0.018 14.9 1.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SURF1 PF02104.10 CCH60341.1 - 4.2e-61 206.4 0.0 6.1e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Acetyltransf_7 PF13508.1 CCH60342.1 - 7.1e-07 29.2 0.0 1.5e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCH60342.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_98M PF08306.6 CCH60342.1 - 0.018 13.7 1.8 0.22 10.2 1.2 2.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 98 Acetyltransf_3 PF13302.1 CCH60342.1 - 0.02 15.0 0.0 0.054 13.6 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCH60342.1 - 0.023 14.7 0.0 0.061 13.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FR47 PF08445.5 CCH60342.1 - 0.095 12.4 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Peptidase_M16 PF00675.15 CCH60343.1 - 1.4e-30 105.9 0.1 6.6e-30 103.8 0.1 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCH60343.1 - 2.6e-22 79.3 2.6 1e-09 38.3 0.0 4.8 4 1 0 4 4 4 3 Peptidase M16 inactive domain Spc97_Spc98 PF04130.8 CCH60344.1 - 2.9e-59 200.8 31.7 2.9e-59 200.8 22.0 1.8 2 0 0 2 2 2 1 Spc97 / Spc98 family DUF1786 PF08735.5 CCH60344.1 - 0.2 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) VPS11_C PF12451.3 CCH60344.1 - 1.8 8.4 4.6 40 4.1 0.0 3.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal MFS_1 PF07690.11 CCH60345.1 - 6.7e-23 80.9 42.5 6.7e-23 80.9 29.5 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCH60345.1 - 1.6e-06 26.8 28.1 1.6e-06 26.8 19.5 2.7 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 CCH60345.1 - 0.0004 20.1 1.2 0.0004 20.1 0.9 2.6 2 0 0 2 2 2 1 MFS_1 like family SieB PF14163.1 CCH60345.1 - 0.24 10.9 0.1 0.24 10.9 0.1 3.2 5 0 0 5 5 5 0 Superinfection exclusion protein B MFS_1 PF07690.11 CCH60346.1 - 2.8e-23 82.2 36.9 1.3e-22 80.0 26.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ETRAMP PF09716.5 CCH60346.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.9 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) MutS_V PF00488.16 CCH60347.1 - 1.9e-81 272.9 0.1 3e-81 272.2 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCH60347.1 - 7.1e-33 114.1 2.2 9.1e-33 113.7 0.6 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CCH60347.1 - 1.6e-26 92.5 1.4 5e-26 90.9 0.1 2.4 3 0 0 3 3 3 1 MutS domain I MutS_II PF05188.12 CCH60347.1 - 2.7e-11 43.6 0.1 9.7e-11 41.8 0.1 1.9 1 0 0 1 1 1 1 MutS domain II DUF2585 PF10755.4 CCH60347.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) N-SET PF11764.3 CCH60348.1 - 1e-36 126.3 2.7 1e-36 126.3 1.9 5.4 6 1 1 7 7 7 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 CCH60348.1 - 3.9e-21 76.0 0.1 3.9e-21 76.0 0.1 4.9 4 2 0 4 4 4 1 SET domain SET_assoc PF11767.3 CCH60348.1 - 1.5e-16 59.4 0.1 3.3e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated ORC6 PF05460.8 CCH60349.1 - 1e-69 235.3 13.3 1e-68 232.0 9.2 1.9 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) FadA PF09403.5 CCH60349.1 - 0.091 12.7 2.1 0.21 11.6 1.5 1.6 1 0 0 1 1 1 0 Adhesion protein FadA DUF1980 PF09323.5 CCH60349.1 - 0.62 9.7 0.0 0.62 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PDZ_1 PF12812.2 CCH60350.1 - 3.7e-46 154.9 3.6 1.4e-30 104.9 0.0 3.9 4 0 0 4 4 4 2 PDZ-like domain PDZ_2 PF13180.1 CCH60350.1 - 1.2e-13 50.6 1.4 3.3e-06 26.8 0.0 4.0 4 0 0 4 4 4 2 PDZ domain Trypsin_2 PF13365.1 CCH60350.1 - 3.7e-13 49.5 0.0 4e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ PF00595.19 CCH60350.1 - 1.6e-12 47.4 0.1 1.8e-08 34.4 0.0 3.0 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 CCH60350.1 - 0.00058 19.6 0.2 2.4 8.0 0.0 3.6 4 0 0 4 4 4 2 Tricorn protease PDZ domain Trypsin PF00089.21 CCH60350.1 - 0.00099 18.7 0.0 0.0027 17.3 0.0 1.7 1 1 0 1 1 1 1 Trypsin DUF31 PF01732.11 CCH60350.1 - 0.012 15.0 0.1 0.027 13.8 0.1 1.6 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 CCH60350.1 - 0.038 13.3 0.1 0.1 11.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease SRP9-21 PF05486.7 CCH60350.1 - 0.081 12.6 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) TPR_11 PF13414.1 CCH60351.1 - 6e-30 102.6 32.7 3.8e-16 58.4 1.0 7.1 5 2 3 8 8 7 7 TPR repeat TPR_1 PF00515.23 CCH60351.1 - 2.1e-19 68.2 36.4 9.4e-07 28.1 0.5 9.8 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCH60351.1 - 3.4e-19 67.1 33.2 0.0013 18.5 0.0 11.0 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCH60351.1 - 5.1e-16 58.8 9.9 0.0035 17.9 0.0 6.4 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCH60351.1 - 3e-13 49.4 24.4 8.7e-06 25.5 0.1 7.4 5 3 5 10 10 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 CCH60351.1 - 3.8e-12 45.6 5.0 1 10.2 0.0 8.5 5 2 4 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCH60351.1 - 3.9e-12 45.0 34.8 0.0061 16.2 0.6 9.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCH60351.1 - 7.5e-11 42.2 13.2 0.033 14.5 0.0 6.8 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCH60351.1 - 3.4e-10 39.2 16.6 0.038 14.1 0.9 8.4 8 2 1 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH60351.1 - 2.4e-06 26.9 10.3 0.69 9.8 0.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCH60351.1 - 0.00047 19.9 0.0 0.93 9.3 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 CCH60351.1 - 0.2 10.3 29.0 0.5 9.0 0.0 4.1 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 Exonuc_VII_S PF02609.11 CCH60351.1 - 1 9.1 9.4 0.5 10.1 0.6 4.3 4 0 0 4 4 4 0 Exonuclease VII small subunit Apc3 PF12895.2 CCH60351.1 - 1.6 8.9 27.3 3.2 7.9 1.6 5.8 4 2 4 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 CCH60351.1 - 7.7 6.7 6.5 1.4e+02 2.8 0.0 4.5 4 0 0 4 4 4 0 PPR repeat DUF2392 PF10288.4 CCH60352.1 - 7.6e-30 103.4 0.6 7.6e-30 103.4 0.4 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2392) zf-RING_2 PF13639.1 CCH60352.1 - 8 6.3 8.1 4.2 7.2 2.2 2.7 3 0 0 3 3 3 0 Ring finger domain DCP2 PF05026.8 CCH60353.1 - 7.9e-31 105.8 0.6 1.6e-30 104.7 0.4 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CCH60353.1 - 6.5e-16 58.1 0.1 2.1e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain SUZ PF12752.2 CCH60353.1 - 0.87 10.1 6.0 5.4 7.6 0.0 3.3 3 0 0 3 3 3 0 SUZ domain SH3_1 PF00018.23 CCH60354.1 - 6.5e-27 92.6 0.3 3.8e-12 45.4 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCH60354.1 - 5.6e-26 89.8 0.2 3.6e-12 45.6 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain FCH PF00611.18 CCH60354.1 - 9.3e-19 67.4 0.2 9.3e-19 67.4 0.1 2.8 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 CCH60354.1 - 2.2e-10 39.8 0.0 0.00012 21.4 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain ITAM PF02189.10 CCH60354.1 - 0.0018 18.4 0.2 0.0075 16.4 0.0 2.2 2 0 0 2 2 2 1 Immunoreceptor tyrosine-based activation motif SH3_3 PF08239.6 CCH60354.1 - 0.016 15.3 0.6 0.071 13.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial SH3 domain TRAPP PF04051.11 CCH60355.1 - 7.1e-32 110.0 0.3 1.1e-31 109.3 0.2 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component TRAP_alpha PF03896.11 CCH60355.1 - 0.095 11.6 1.7 5.8 5.8 1.1 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DEAD PF00270.24 CCH60356.1 - 1.5e-44 151.4 0.0 1.7e-43 148.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH60356.1 - 4.2e-29 100.2 0.0 1.6e-28 98.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH60356.1 - 0.0085 15.9 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCH60356.1 - 0.013 13.9 0.0 0.076 11.4 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 CCH60356.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.1 CCH60356.1 - 0.095 12.4 0.0 20 5.0 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain Cnd1 PF12717.2 CCH60357.1 - 0.00018 21.3 1.8 0.016 15.0 0.0 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCH60357.1 - 0.025 14.6 0.1 48 4.4 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat RRM_1 PF00076.17 CCH60358.1 - 4.9e-18 64.5 0.1 1.1e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60358.1 - 2.4e-13 49.8 0.1 9.3e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60358.1 - 1e-10 41.2 0.1 2e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4135 PF13575.1 CCH60358.1 - 0.022 13.7 1.3 0.048 12.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4135) Syja_N PF02383.13 CCH60359.1 - 1.4e-88 296.7 0.9 2.2e-88 296.1 0.6 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCH60359.1 - 1.3e-24 87.5 0.0 3.3e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SNARE PF05739.14 CCH60360.1 - 1.1e-14 53.8 3.7 1.1e-14 53.8 2.6 2.3 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.16 CCH60360.1 - 0.0012 18.4 0.4 0.0012 18.4 0.3 2.7 3 0 0 3 3 3 1 Synaptobrevin Imm14 PF15428.1 CCH60360.1 - 0.025 14.9 1.5 0.046 14.1 1.0 1.5 1 0 0 1 1 1 0 Immunity protein 14 Syntaxin-6_N PF09177.6 CCH60360.1 - 0.059 13.7 0.4 0.059 13.7 0.3 2.8 2 2 0 3 3 3 0 Syntaxin 6, N-terminal DUF3708 PF12501.3 CCH60360.1 - 0.18 11.6 0.4 0.48 10.2 0.1 1.8 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter DUF1664 PF07889.7 CCH60360.1 - 0.93 9.3 13.9 0.98 9.2 0.4 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Aa_trans PF01490.13 CCH60361.1 - 2.2e-86 289.8 38.6 2.7e-86 289.5 26.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CCH60361.1 - 0.00023 19.8 41.4 0.0003 19.4 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease ATP13 PF12921.2 CCH60361.1 - 0.028 13.7 0.1 0.066 12.5 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ATPase expression Glyco_transf_34 PF05637.7 CCH60362.1 - 3.9e-47 160.7 0.0 5.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ATG27 PF09451.5 CCH60363.1 - 4e-48 163.9 0.3 5.2e-48 163.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 SEA PF01390.15 CCH60363.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 SEA domain Adeno_E3_CR1 PF02440.10 CCH60363.1 - 0.6 9.6 3.2 0.73 9.3 0.5 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR1 Ribosomal_L22 PF00237.14 CCH60364.1 - 2.7e-33 114.0 1.7 3.7e-33 113.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CASP_C PF08172.7 CCH60365.1 - 2.7e-31 108.4 10.5 3.2e-26 91.8 4.8 5.9 2 1 2 6 6 6 3 CASP C terminal TRIQK PF15168.1 CCH60365.1 - 0.0072 16.2 0.1 2.4 8.1 0.0 2.9 2 0 0 2 2 2 2 Triple QxxK/R motif-containing protein family Filament PF00038.16 CCH60365.1 - 1.4 8.3 58.0 2.6 7.4 12.0 4.3 2 2 2 4 4 4 0 Intermediate filament protein KRE9 PF05390.6 CCH60366.1 - 1.2e-39 135.0 5.2 2.4e-39 133.9 3.6 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCH60366.1 - 1.6e-08 34.8 0.8 1.6e-08 34.8 0.6 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rep_fac-A_3 PF08661.6 CCH60367.1 - 2.4e-22 78.8 0.0 2.8e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 MFS_1 PF07690.11 CCH60368.1 - 3.6e-34 118.0 22.2 5.2e-34 117.5 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Arginosuc_synth PF00764.14 CCH60369.1 - 1.6e-160 534.4 0.0 1.8e-160 534.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 CCH60369.1 - 2.1e-05 24.1 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CCH60369.1 - 2.5e-05 23.6 0.0 5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CCH60369.1 - 0.00063 18.4 0.0 0.00095 17.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase DUF2401 PF10287.4 CCH60370.1 - 5.5e-89 297.6 1.1 7.1e-89 297.3 0.8 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCH60370.1 - 4.8e-25 87.5 0.0 1.2e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Resistin PF06954.6 CCH60370.1 - 4.3 7.6 6.2 21 5.4 0.2 3.2 3 0 0 3 3 3 0 Resistin DUF2079 PF09852.4 CCH60371.1 - 0.01 14.5 0.8 0.022 13.5 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DUF2520 PF10728.4 CCH60371.1 - 0.073 12.5 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) AA_permease PF00324.16 CCH60372.1 - 4.9e-77 259.3 46.5 5.9e-77 259.0 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH60372.1 - 3.8e-37 127.8 51.2 5e-37 127.4 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.22 CCH60373.1 - 7e-33 113.6 0.0 1.4e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCH60373.1 - 2.1e-14 53.1 0.0 4.3e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CCH60373.1 - 4.3e-14 52.1 0.0 1.2e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCH60373.1 - 4.9e-07 29.4 0.0 1.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CCH60373.1 - 9.8e-05 22.8 0.0 0.00026 21.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CCH60373.1 - 0.00036 20.6 0.2 0.002 18.2 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.5 CCH60373.1 - 0.0023 17.1 0.0 0.13 11.4 0.0 2.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCH60373.1 - 0.0033 17.3 0.1 0.0077 16.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ebp2 PF05890.7 CCH60374.1 - 1.5e-87 293.3 30.0 1.5e-87 293.3 20.8 3.2 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.12 CCH60375.1 - 8.8e-84 280.3 0.0 1.1e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.11 CCH60376.1 - 5.6e-37 125.4 1.1 6.4e-37 125.2 0.8 1.0 1 0 0 1 1 1 1 UcrQ family Ribosomal_L14 PF00238.14 CCH60377.1 - 3.5e-40 136.5 1.9 3.9e-40 136.4 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 CCH60378.1 - 2.7e-45 154.5 0.7 5.6e-45 153.5 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60378.1 - 2.4e-18 66.1 0.1 4.2e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH60378.1 - 0.0034 16.4 0.0 0.0054 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH60378.1 - 0.024 13.7 0.2 0.05 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Innate_immun PF12782.2 CCH60378.1 - 1.5 7.9 11.7 1.5 7.9 0.8 2.2 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Zip PF02535.17 CCH60378.1 - 8.9 5.2 15.4 2.1 7.2 1.2 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter L51_S25_CI-B8 PF05047.11 CCH60379.1 - 2.8e-07 30.1 0.4 2.8e-07 30.1 0.3 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF16 PF01519.11 CCH60379.1 - 0.00054 20.1 1.7 0.00054 20.1 1.2 1.5 2 0 0 2 2 2 1 Protein of unknown function DUF16 DUF1108 PF06531.6 CCH60379.1 - 0.1 12.7 0.3 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1108) Arf PF00025.16 CCH60379.1 - 0.12 11.6 0.6 0.26 10.5 0.4 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family CAAP1 PF15335.1 CCH60379.1 - 0.39 10.9 3.2 0.28 11.4 0.4 2.1 2 1 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Pkinase PF00069.20 CCH60380.1 - 6.5e-72 241.7 0.0 8.9e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60380.1 - 1.1e-41 142.5 0.0 1.6e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH60380.1 - 1.6e-05 24.0 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCH60380.1 - 0.049 12.9 0.0 0.098 11.9 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCH60380.1 - 0.063 12.9 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCH60380.1 - 0.089 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CCH60380.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PigN PF04987.9 CCH60381.1 - 5e-131 437.3 49.7 6.6e-131 436.9 34.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CCH60381.1 - 1.5e-14 54.0 0.2 2.9e-10 40.0 0.0 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CCH60381.1 - 8e-11 41.6 0.1 1.3e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CCH60381.1 - 0.00015 21.2 0.1 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily PIR PF00399.14 CCH60382.1 - 9.7e-55 180.1 115.5 3.4e-07 29.3 6.4 8.8 8 0 0 8 8 8 8 Yeast PIR protein repeat PIR PF00399.14 CCH60383.1 - 9.7e-14 50.1 39.5 1.5e-05 24.1 3.0 4.1 4 0 0 4 4 4 3 Yeast PIR protein repeat YCII PF03795.9 CCH60384.1 - 5.8e-08 32.8 0.0 6.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain PIR PF00399.14 CCH60385.1 - 1.1e-06 27.6 4.8 1.1e-06 27.6 3.4 2.4 2 0 0 2 2 2 1 Yeast PIR protein repeat HypA PF01155.14 CCH60386.1 - 0.57 9.8 4.7 4.2 7.0 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DnaJ_CXXCXGXG PF00684.14 CCH60386.1 - 0.63 10.1 12.4 2.5 8.2 2.4 2.3 2 0 0 2 2 2 0 DnaJ central domain DUF2318 PF10080.4 CCH60386.1 - 0.63 9.8 0.1 0.63 9.8 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Vps35 PF03635.12 CCH60387.1 - 1.4e-242 807.1 43.2 6.3e-242 805.0 30.0 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 peroxidase PF00141.18 CCH60388.1 - 1.7e-40 138.9 0.0 3.3e-40 137.9 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Pam17 PF08566.5 CCH60389.1 - 6.4e-70 234.3 0.1 8.3e-70 233.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF4260 PF14079.1 CCH60389.1 - 0.055 13.2 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4260) F-box PF00646.28 CCH60390.1 - 1.4e-06 27.7 1.3 1.4e-06 27.7 0.9 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 CCH60390.1 - 4.9e-06 26.1 0.6 4.9e-06 26.1 0.4 2.6 2 0 0 2 2 2 1 F-box-like Yip1 PF04893.12 CCH60391.1 - 8.1e-14 51.4 9.0 1.1e-13 51.0 6.2 1.3 1 0 0 1 1 1 1 Yip1 domain MMR_HSR1 PF01926.18 CCH60392.1 - 3.5e-19 68.8 0.1 1.2e-18 67.1 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CCH60392.1 - 4e-19 68.2 0.0 8.1e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCH60392.1 - 9.2e-13 47.7 0.0 1.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCH60392.1 - 1.6e-05 24.7 0.6 0.0087 15.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CCH60392.1 - 0.00082 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CCH60392.1 - 0.0038 17.7 0.0 0.011 16.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 CCH60392.1 - 0.024 13.8 0.3 0.079 12.1 0.0 1.9 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Ribonuc_red_sm PF00268.16 CCH60393.1 - 5.8e-106 353.5 2.3 1.1e-105 352.6 1.6 1.4 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain RRN7 PF11781.3 CCH60394.1 - 1e-06 28.1 0.1 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 SE PF08491.5 CCH60395.1 - 4.1e-118 393.2 0.0 5.6e-118 392.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CCH60395.1 - 1.4e-13 50.6 0.0 2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCH60395.1 - 9.9e-06 24.6 0.1 3e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCH60395.1 - 0.00043 20.2 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCH60395.1 - 0.00064 19.7 0.1 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCH60395.1 - 0.0013 17.7 0.1 0.0022 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCH60395.1 - 0.0032 16.5 1.5 0.0041 16.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 CCH60395.1 - 0.0063 16.9 0.2 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCH60395.1 - 0.026 13.0 0.8 0.068 11.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein GDI PF00996.13 CCH60395.1 - 0.026 12.8 0.0 0.04 12.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor 3HCDH_N PF02737.13 CCH60395.1 - 0.031 13.9 0.2 0.054 13.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 CCH60395.1 - 0.14 11.2 0.3 0.33 9.9 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 CCH60395.1 - 0.29 9.9 0.8 0.63 8.8 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A CBP4 PF07960.6 CCH60396.1 - 2.4e-35 120.9 1.8 2.8e-35 120.7 1.2 1.0 1 0 0 1 1 1 1 CBP4 Sec10 PF07393.6 CCH60397.1 - 2.2e-51 174.9 40.2 2.9e-51 174.5 18.1 2.2 1 1 0 2 2 2 2 Exocyst complex component Sec10 MAS20 PF02064.10 CCH60397.1 - 0.015 15.1 0.5 0.08 12.8 0.2 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor SPX PF03105.14 CCH60398.1 - 2.7e-31 109.3 42.8 2e-29 103.2 29.7 2.2 1 1 0 1 1 1 1 SPX domain CitMHS PF03600.11 CCH60398.1 - 5.1e-14 51.6 39.0 1.6e-10 40.1 17.7 2.2 1 1 1 2 2 2 2 Citrate transporter DctM PF06808.7 CCH60398.1 - 0.00041 19.0 14.6 0.00041 19.0 10.2 2.6 1 1 1 2 2 2 1 DctM-like transporters Peptidase_S49 PF01343.13 CCH60398.1 - 0.11 12.3 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 RNase_PH PF01138.16 CCH60399.1 - 7.7e-17 61.8 0.0 1.6e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FYVE_2 PF02318.11 CCH60399.1 - 0.034 14.0 0.2 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger ELO PF01151.13 CCH60400.1 - 7.7e-58 195.7 24.8 1.2e-57 195.1 17.2 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family OapA_N PF08525.6 CCH60400.1 - 0.032 14.0 0.3 0.082 12.6 0.2 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif UCR_UQCRX_QCR9 PF05365.7 CCH60401.1 - 1e-25 89.0 4.3 1.2e-25 88.9 3.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like HlyIII PF03006.15 CCH60402.1 - 2.1e-61 207.1 16.2 2.5e-61 206.8 11.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Abhydro_lipase PF04083.11 CCH60403.1 - 7.3e-11 41.2 0.0 1.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region DUF900 PF05990.7 CCH60403.1 - 0.00093 18.5 0.0 0.0022 17.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.2 CCH60403.1 - 0.0051 16.7 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH60403.1 - 0.0052 16.3 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold chaperone_DMP PF10448.4 CCH60404.1 - 7.5e-29 100.4 1.9 8.7e-29 100.2 1.3 1.1 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 CCH60405.1 - 7.2e-34 116.1 0.4 7.2e-34 116.1 0.3 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 CCH60405.1 - 3.4e-33 113.3 1.5 6e-33 112.5 0.6 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NIF PF03031.13 CCH60406.1 - 2.3e-50 170.3 0.6 2.3e-50 170.3 0.4 2.5 2 1 2 4 4 4 1 NLI interacting factor-like phosphatase I_LWEQ PF01608.12 CCH60406.1 - 0.03 14.2 7.4 0.061 13.2 5.1 1.5 1 0 0 1 1 1 0 I/LWEQ domain NPCC PF08058.6 CCH60407.1 - 1.5e-26 93.0 4.9 1.5e-26 93.0 3.4 2.3 2 0 0 2 2 2 1 Nuclear pore complex component PNP_UDP_1 PF01048.15 CCH60408.1 - 1.7e-34 118.8 0.0 2.1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily COX17 PF05051.8 CCH60409.1 - 1.5e-21 76.1 8.2 1.9e-21 75.8 5.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 CCH60409.1 - 0.0021 17.9 2.9 0.0043 16.9 2.0 1.6 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCH60409.1 - 0.0077 15.9 0.2 0.0077 15.9 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 CCH60409.1 - 0.68 9.8 8.6 7 6.5 5.8 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) PP2C PF00481.16 CCH60410.1 - 2.7e-51 174.4 0.3 2.7e-51 174.4 0.2 2.5 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 CCH60410.1 - 3.9e-42 141.2 86.4 9.4e-08 31.5 2.7 12.9 6 4 7 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH60410.1 - 7.6e-37 124.8 75.3 8.3e-09 35.0 2.4 10.2 5 3 5 10 10 10 9 Leucine rich repeat Guanylate_cyc PF00211.15 CCH60410.1 - 2.2e-24 85.8 0.0 4.1e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CCH60410.1 - 1.5e-13 48.7 69.7 0.11 12.5 0.8 16.7 14 3 1 15 15 15 6 Leucine Rich Repeat RA PF00788.18 CCH60410.1 - 6.9e-08 32.8 0.1 2.3e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CCH60410.1 - 5.3e-05 22.7 56.8 1.1 9.7 0.9 14.8 16 0 0 16 16 16 3 Leucine rich repeat LRR_6 PF13516.1 CCH60410.1 - 0.26 11.4 79.0 0.23 11.6 0.2 15.9 13 4 2 15 15 15 0 Leucine Rich repeat LRR_9 PF14580.1 CCH60410.1 - 0.49 9.9 14.7 0.22 11.0 3.3 3.5 2 1 3 5 5 5 0 Leucine-rich repeat DUF2065 PF09838.4 CCH60410.1 - 0.85 9.3 0.0 1.7 8.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) SYS1 PF09801.4 CCH60411.1 - 1.1e-47 161.6 13.9 1.3e-47 161.4 9.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network K_trans PF02705.11 CCH60411.1 - 0.00071 18.0 0.3 0.001 17.4 0.2 1.2 1 0 0 1 1 1 1 K+ potassium transporter DEAD PF00270.24 CCH60412.1 - 1e-45 155.2 0.1 1e-45 155.2 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH60412.1 - 4.5e-25 87.3 0.0 1.3e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCH60412.1 - 0.077 13.1 0.3 0.3 11.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain COX16 PF14138.1 CCH60413.1 - 3.9e-32 110.2 0.8 4.6e-32 110.0 0.1 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 RseA_N PF03872.8 CCH60414.1 - 0.0007 19.8 0.1 0.002 18.3 0.1 1.7 1 0 0 1 1 1 1 Anti sigma-E protein RseA, N-terminal domain Ribophorin_I PF04597.9 CCH60415.1 - 6e-119 397.3 8.8 6.9e-119 397.1 6.1 1.0 1 0 0 1 1 1 1 Ribophorin I Proteasome PF00227.21 CCH60416.1 - 2.5e-46 157.3 0.3 2.9e-46 157.1 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit A_thal_3526 PF09713.5 CCH60416.1 - 0.052 13.6 0.0 5.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Fasciclin PF02469.17 CCH60417.1 - 8.1e-21 74.3 0.9 1.1e-05 25.4 0.0 6.0 5 2 0 5 5 5 5 Fasciclin domain FA_desaturase PF00487.19 CCH60418.1 - 2.1e-18 66.7 15.3 2.1e-18 66.7 10.6 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCH60418.1 - 3.2e-14 52.4 0.1 4.4e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Zn_clus PF00172.13 CCH60419.1 - 1.6e-08 34.3 12.3 3.3e-08 33.3 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mucin PF01456.12 CCH60419.1 - 1.8 8.3 17.9 3 7.6 12.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 CCH60419.1 - 2 8.1 8.0 4.2 7.1 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mannosyl_trans3 PF11051.3 CCH60420.1 - 2.4e-61 207.4 2.4 3.8e-61 206.8 1.7 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Ribonuclease_3 PF00636.21 CCH60421.1 - 9.6e-18 64.7 0.0 9.6e-18 64.7 0.0 4.3 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCH60421.1 - 2.3e-14 53.4 0.0 7.7e-14 51.7 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCH60421.1 - 8.1e-14 51.9 0.2 5.2e-07 30.1 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif TFIID-18kDa PF02269.11 CCH60422.1 - 7.3e-33 112.2 0.0 1e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF4611 PF15387.1 CCH60422.1 - 0.00028 20.9 7.4 0.00049 20.1 5.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Histone PF00125.19 CCH60422.1 - 0.0054 16.8 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Nucleoplasmin PF03066.10 CCH60422.1 - 0.016 14.7 6.1 0.022 14.2 4.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 CCH60422.1 - 0.41 10.3 7.8 0.6 9.7 5.4 1.3 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.6 CCH60422.1 - 1.1 7.1 6.3 1 7.1 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 CCH60422.1 - 3.9 7.8 14.6 6.7 7.1 10.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ERO1 PF04137.10 CCH60423.1 - 3.1e-117 391.5 4.3 3.1e-117 391.5 3.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF2401 PF10287.4 CCH60423.1 - 0.016 14.7 1.3 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative TOS1-like glycosyl hydrolase (DUF2401) VPS9 PF02204.13 CCH60424.1 - 5e-28 97.1 0.4 1.7e-27 95.4 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CCH60424.1 - 8.5e-07 28.3 0.0 2e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 CUE domain AKAP95 PF04988.7 CCH60424.1 - 0.028 14.2 0.4 0.028 14.2 0.3 2.6 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Asn_synthase PF00733.16 CCH60425.1 - 1.9e-44 152.1 0.0 2.9e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCH60425.1 - 9e-15 54.5 0.0 2.5e-13 49.8 0.0 2.6 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCH60425.1 - 1.7e-08 34.4 0.0 6.1e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCH60425.1 - 0.0017 17.6 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein Rad10 PF03834.9 CCH60426.1 - 1.5e-24 85.4 1.4 2.7e-24 84.6 0.9 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Glyco_tranf_2_2 PF10111.4 CCH60426.1 - 0.011 14.8 1.6 0.011 14.8 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 Prefoldin PF02996.12 CCH60427.1 - 3.1e-26 91.3 3.8 3.7e-26 91.1 2.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit ORC4_C PF14629.1 CCH60427.1 - 0.0037 16.6 0.4 0.034 13.5 0.0 1.9 1 1 1 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus Prefoldin_3 PF13758.1 CCH60427.1 - 0.016 14.9 2.3 0.078 12.7 0.5 2.4 2 1 1 3 3 3 0 Prefoldin subunit DUF4407 PF14362.1 CCH60427.1 - 0.04 12.8 1.1 0.049 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_I6 PF04595.8 CCH60427.1 - 0.061 12.0 0.4 0.075 11.7 0.3 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family HAUS2 PF15003.1 CCH60427.1 - 0.098 11.7 1.8 3.2 6.7 0.7 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 DUF1664 PF07889.7 CCH60427.1 - 0.27 11.0 3.5 3.7 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Flagellar_rod PF05149.7 CCH60427.1 - 0.75 8.9 9.6 4.9 6.2 0.1 2.1 2 0 0 2 2 2 0 Paraflagellar rod protein Fib_alpha PF08702.5 CCH60427.1 - 1.6 8.8 9.9 2.4 8.2 0.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Utp14 PF04615.8 CCH60428.1 - 1.4e-188 628.5 83.5 1.4e-188 628.5 57.9 2.2 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.21 CCH60429.1 - 6.8e-56 188.5 0.0 8.4e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH60429.1 - 4.9e-09 35.3 0.4 1e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RPM2 PF08579.6 CCH60430.1 - 3.8e-35 120.6 2.7 3.8e-35 120.6 1.9 4.3 3 0 0 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) RVT_1 PF00078.22 CCH60431.1 - 2.1e-10 40.3 0.7 7e-10 38.6 0.4 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) CheW PF01584.14 CCH60431.1 - 0.045 13.2 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 CheW-like domain rve PF00665.21 CCH60432.1 - 2.1e-12 47.2 0.0 3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain ABC_membrane PF00664.18 CCH60433.1 - 1.2e-55 188.9 43.0 2.7e-32 112.2 9.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCH60433.1 - 1.3e-47 161.5 0.2 6.2e-28 97.8 0.0 3.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCH60433.1 - 6.1e-13 48.5 0.0 0.00014 21.2 0.0 4.3 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCH60433.1 - 7.4e-12 46.0 1.1 7.4e-12 46.0 0.8 3.8 3 2 1 4 4 3 2 AAA domain AAA_29 PF13555.1 CCH60433.1 - 9.8e-09 34.6 0.1 0.001 18.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH60433.1 - 4e-07 30.2 12.0 0.22 11.4 0.0 6.1 5 1 1 6 6 5 2 AAA domain AAA_17 PF13207.1 CCH60433.1 - 8e-07 29.9 0.0 0.02 15.6 0.0 3.4 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 CCH60433.1 - 3.7e-05 22.9 0.0 0.047 12.8 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CCH60433.1 - 5.7e-05 22.1 0.0 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 CCH60433.1 - 9.1e-05 22.9 0.8 1 9.8 0.0 3.6 4 0 0 4 4 2 2 Miro-like protein AAA_18 PF13238.1 CCH60433.1 - 0.0001 22.6 1.0 0.64 10.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CCH60433.1 - 0.00012 21.9 2.8 0.43 10.5 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase cobW PF02492.14 CCH60433.1 - 0.00022 20.7 0.2 0.031 13.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CCH60433.1 - 0.0003 20.3 0.1 0.28 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA-like domain AAA_22 PF13401.1 CCH60433.1 - 0.00044 20.3 0.3 1.2 9.2 0.0 3.7 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 CCH60433.1 - 0.00052 19.8 2.5 0.35 10.6 0.0 3.6 3 0 0 3 3 3 1 Dynamin family AAA_30 PF13604.1 CCH60433.1 - 0.0013 18.4 0.5 2.5 7.6 0.1 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 CCH60433.1 - 0.0034 17.0 0.1 1.4 8.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCH60433.1 - 0.0038 17.2 1.7 0.072 13.0 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCH60433.1 - 0.0052 16.2 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CCH60433.1 - 0.0084 15.2 0.1 0.69 8.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin ATP_bind_1 PF03029.12 CCH60433.1 - 0.011 15.3 0.4 3.5 7.1 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 CCH60433.1 - 0.011 14.9 0.0 0.06 12.4 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 CCH60433.1 - 0.014 14.9 0.1 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 CCH60433.1 - 0.014 15.2 0.0 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCH60433.1 - 0.015 15.4 0.3 0.58 10.3 0.1 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCH60433.1 - 0.018 14.4 1.2 0.91 8.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain Vps51 PF08700.6 CCH60433.1 - 0.033 14.0 3.2 2.5 7.9 0.1 3.0 2 0 0 2 2 2 0 Vps51/Vps67 ArgK PF03308.11 CCH60433.1 - 0.037 12.8 0.1 0.093 11.4 0.0 1.6 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 CCH60433.1 - 0.037 13.6 0.2 0.42 10.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 CCH60433.1 - 0.038 13.6 0.0 0.038 13.6 0.0 3.7 5 0 0 5 5 3 0 Archaeal ATPase GTP_EFTU PF00009.22 CCH60433.1 - 0.041 13.2 0.0 17 4.7 0.0 3.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCH60433.1 - 0.046 13.2 0.6 0.45 10.0 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 CCH60433.1 - 0.069 12.5 1.5 0.78 9.1 0.0 3.1 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_19 PF13245.1 CCH60433.1 - 0.28 10.9 5.7 0.4 10.4 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain ABC_ATPase PF09818.4 CCH60433.1 - 1.3 7.5 3.7 13 4.2 0.1 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SUR7 PF06687.7 CCH60434.1 - 1.4e-15 57.4 22.4 1.9e-15 57.0 15.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family HA2 PF04408.18 CCH60435.1 - 2.6e-19 69.1 0.1 2.6e-19 69.1 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCH60435.1 - 2.3e-17 62.8 0.0 5.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCH60435.1 - 1.9e-10 40.4 0.0 5.3e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH60435.1 - 2e-07 30.6 0.1 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH60435.1 - 1.4e-06 28.4 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CCH60435.1 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 CCH60435.1 - 0.0015 18.0 0.1 0.0074 15.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_11 PF13086.1 CCH60435.1 - 0.003 17.1 0.9 0.088 12.3 0.1 2.8 1 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCH60435.1 - 0.0032 17.7 0.4 0.15 12.3 0.1 3.2 2 1 0 3 3 3 1 ABC transporter Arch_ATPase PF01637.13 CCH60435.1 - 0.0034 17.1 0.2 0.0087 15.7 0.1 1.6 1 0 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 CCH60435.1 - 0.0038 16.4 0.1 0.009 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRP54 PF00448.17 CCH60435.1 - 0.0083 15.5 0.0 0.026 13.9 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CCH60435.1 - 0.02 14.7 0.7 0.54 10.1 0.2 3.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCH60435.1 - 0.045 13.5 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 CCH60435.1 - 0.066 12.8 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Flavi_DEAD PF07652.9 CCH60435.1 - 0.096 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SE PF00437.15 CCH60435.1 - 0.097 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Suf PF05843.9 CCH60436.1 - 7.1e-68 229.3 11.2 7.1e-68 229.3 7.8 3.7 2 2 1 3 3 3 2 Suppressor of forked protein (Suf) SH3_2 PF07653.12 CCH60437.1 - 2.2e-07 30.2 0.0 4.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCH60437.1 - 4.4e-07 29.1 0.1 1.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH60437.1 - 5.5e-07 29.0 0.1 1.2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PseudoU_synth_2 PF00849.17 CCH60438.1 - 1.3e-24 86.8 0.0 1.8e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase UPF0547 PF10571.4 CCH60438.1 - 0.076 12.7 0.5 0.17 11.6 0.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Ank_2 PF12796.2 CCH60440.1 - 4e-25 87.9 0.0 3e-13 49.9 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) SPX PF03105.14 CCH60440.1 - 1.1e-24 87.6 21.7 3.4e-13 50.0 6.7 3.4 3 1 1 4 4 4 2 SPX domain Ank PF00023.25 CCH60440.1 - 3.6e-20 70.6 0.6 7.3e-05 22.3 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 CCH60440.1 - 9.2e-16 56.3 0.8 0.035 14.3 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CCH60440.1 - 2.3e-15 56.5 1.5 0.00029 21.2 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCH60440.1 - 1.4e-14 53.7 10.2 6.1e-05 23.1 0.0 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) GDPD PF03009.12 CCH60440.1 - 3e-06 26.9 0.0 0.00012 21.6 0.0 2.7 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF1938 PF09153.5 CCH60441.1 - 0.065 13.0 1.1 0.14 12.0 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) BRCT PF00533.21 CCH60442.1 - 7.8e-08 32.3 17.7 5.2e-05 23.3 0.0 5.5 7 0 0 7 7 7 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCH60442.1 - 0.067 13.0 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 twin BRCT domain FAD_binding_6 PF00970.19 CCH60443.1 - 1.4e-10 41.1 0.0 3.3e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CCH60443.1 - 5.6e-09 36.3 0.0 2.2e-08 34.4 0.0 2.0 3 0 0 3 3 3 1 Globin NAD_binding_1 PF00175.16 CCH60443.1 - 3.2e-07 30.8 0.0 7.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCH60443.1 - 0.036 13.9 1.2 0.26 11.1 0.5 2.3 2 1 1 3 3 3 0 Ferric reductase NAD binding domain Protoglobin PF11563.3 CCH60443.1 - 0.072 12.7 0.1 0.29 10.7 0.1 1.9 1 1 0 1 1 1 0 Protoglobin DUF416 PF04222.7 CCH60444.1 - 0.029 13.4 0.3 0.033 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Kelch_5 PF13854.1 CCH60446.1 - 3.1e-31 106.8 4.6 0.00024 20.9 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CCH60446.1 - 5.4e-30 102.8 0.4 3.6e-05 23.8 0.0 6.1 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCH60446.1 - 1.5e-28 98.3 6.2 0.0016 18.1 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CCH60446.1 - 1.4e-24 85.1 5.9 3.8e-05 23.6 0.1 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCH60446.1 - 5.3e-22 77.1 0.5 1.3e-06 27.8 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCH60446.1 - 2.9e-11 42.6 5.2 0.06 13.1 0.0 6.3 6 0 0 6 6 6 3 Kelch motif TSC22 PF01166.13 CCH60446.1 - 0.034 14.0 14.4 0.053 13.4 0.6 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family IncA PF04156.9 CCH60446.1 - 0.92 9.0 46.6 0.28 10.7 3.5 4.2 2 2 2 4 4 4 0 IncA protein ATP-grasp_2 PF08442.5 CCH60449.1 - 3e-72 242.2 1.9 4.6e-72 241.6 1.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CCH60449.1 - 1.4e-21 76.6 0.1 3.1e-20 72.3 0.0 2.4 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 CCH60449.1 - 4.6e-05 22.7 0.6 9.7e-05 21.6 0.4 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CCH60449.1 - 0.0023 17.5 0.3 0.006 16.1 0.2 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 CCH60449.1 - 0.0027 17.1 0.1 0.07 12.6 0.0 2.4 1 1 1 2 2 2 1 RimK-like ATP-grasp domain HIN PF02760.10 CCH60449.1 - 0.056 12.8 0.2 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 HIN-200/IF120x domain SDA1 PF05285.7 CCH60450.1 - 7.5e-99 331.0 41.8 7.5e-99 331.0 28.9 2.1 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 CCH60450.1 - 1.1e-22 80.0 0.3 3.2e-22 78.5 0.2 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Trans_reg_C PF00486.23 CCH60450.1 - 0.0027 17.5 0.3 0.067 13.1 0.0 3.1 3 0 0 3 3 3 1 Transcriptional regulatory protein, C terminal Glucosamine_iso PF01182.15 CCH60451.1 - 7.8e-50 169.3 0.0 9e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase GTP1_OBG PF01018.17 CCH60452.1 - 1.5e-32 112.4 1.3 1.2e-23 83.4 1.3 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CCH60452.1 - 8.4e-20 70.8 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH60452.1 - 4.2e-09 35.8 0.0 6.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 CCH60452.1 - 3.5e-07 29.6 0.0 9.4e-07 28.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCH60452.1 - 6.4e-05 23.4 0.0 0.00018 21.9 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCH60452.1 - 0.0018 17.7 0.5 0.19 11.1 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCH60452.1 - 0.0033 16.6 0.0 0.0068 15.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CCH60452.1 - 0.061 13.1 0.0 5.7 6.7 0.1 2.6 1 1 1 2 2 2 0 Dynamin family ArgK PF03308.11 CCH60452.1 - 0.12 11.1 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein NMD3 PF04981.8 CCH60453.1 - 1.6e-75 253.2 3.3 2.7e-75 252.5 2.3 1.4 1 0 0 1 1 1 1 NMD3 family NinF PF05810.7 CCH60453.1 - 0.23 11.2 5.2 6.7 6.5 0.1 3.4 3 0 0 3 3 3 0 NinF protein HypA PF01155.14 CCH60453.1 - 0.28 10.8 4.2 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CCH60453.1 - 0.69 9.7 6.5 1.3 8.9 2.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 CCH60453.1 - 1.5 8.7 9.9 0.29 10.9 0.2 3.3 2 1 1 3 3 3 0 Zinc-ribbon FYVE PF01363.16 CCH60453.1 - 1.6 8.6 7.2 0.93 9.4 1.8 2.4 2 0 0 2 2 2 0 FYVE zinc finger Bromodomain PF00439.20 CCH60454.1 - 9.1e-27 92.8 2.2 2.3e-26 91.5 1.5 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CCH60454.1 - 2.9e-09 36.9 0.3 6.2e-09 35.8 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCH60454.1 - 1.5e-08 34.5 0.1 2.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCH60454.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Proteasome PF00227.21 CCH60455.1 - 4.5e-56 189.1 0.1 6e-56 188.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH60455.1 - 1.6e-13 49.6 0.1 4e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 CCH60457.1 - 7.5e-49 166.4 32.8 7.5e-49 166.4 22.7 1.8 2 1 0 2 2 2 1 Spc97 / Spc98 family Enolase_C PF00113.17 CCH60458.1 - 3e-149 495.8 0.0 4.7e-149 495.2 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCH60458.1 - 9e-58 193.8 0.5 1.4e-57 193.2 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 CCH60458.1 - 0.019 15.4 0.0 0.054 14.0 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 CCH60458.1 - 0.038 13.9 0.2 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Enolase C-terminal domain-like Erv26 PF04148.8 CCH60459.1 - 1.4e-85 285.9 4.4 1.6e-85 285.7 3.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.8 CCH60459.1 - 0.00063 19.7 5.9 0.0013 18.7 4.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF996) ST7 PF04184.7 CCH60459.1 - 2 6.5 5.4 3.9 5.6 3.6 1.4 2 0 0 2 2 2 0 ST7 protein Cytochrom_C_asm PF01578.15 CCH60459.1 - 8 5.9 10.5 1.3 8.4 3.0 2.3 1 1 1 2 2 2 0 Cytochrome C assembly protein 6PGD PF00393.14 CCH60460.1 - 4.8e-134 446.1 0.0 5.9e-134 445.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCH60460.1 - 2.5e-51 173.7 0.0 3.6e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CCH60460.1 - 0.04 13.9 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 CCH60460.1 - 0.15 11.2 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 CCH60462.1 - 9.5e-33 113.3 21.1 9.5e-33 113.3 14.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Elong_Iki1 PF10483.4 CCH60463.1 - 1.5e-64 218.0 2.6 1.8e-64 217.8 1.8 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Vmethyltransf PF01660.12 CCH60463.1 - 0.035 12.7 0.1 0.084 11.5 0.1 1.7 1 1 0 1 1 1 0 Viral methyltransferase DUF835 PF05763.7 CCH60463.1 - 0.04 13.4 0.5 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF835) Gpi16 PF04113.9 CCH60464.1 - 8e-160 532.5 0.8 1e-159 532.1 0.5 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component TT_ORF1 PF02956.9 CCH60464.1 - 0.0028 16.1 0.6 0.0051 15.3 0.4 1.3 1 0 0 1 1 1 1 TT viral orf 1 HEAT_2 PF13646.1 CCH60465.1 - 4.8e-10 39.5 0.0 0.0011 19.2 0.0 6.4 3 2 6 9 9 9 3 HEAT repeats HEAT PF02985.17 CCH60465.1 - 1.3e-06 27.9 7.9 9.8 6.5 0.1 8.4 8 0 0 8 8 8 1 HEAT repeat HEAT_EZ PF13513.1 CCH60465.1 - 0.0019 18.6 0.0 26 5.4 0.0 6.0 7 0 0 7 7 7 1 HEAT-like repeat ParcG PF10274.4 CCH60465.1 - 0.4 10.5 8.5 0.69 9.7 0.0 4.4 4 1 0 5 5 5 0 Parkin co-regulated protein Adaptin_N PF01602.15 CCH60466.1 - 4e-80 269.6 25.7 4.9e-80 269.3 17.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCH60466.1 - 8e-07 29.2 3.9 0.00027 21.1 0.3 4.1 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 CCH60466.1 - 0.00067 19.5 2.4 9.2 6.6 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CCH60466.1 - 0.0097 16.3 2.2 1.6 9.3 0.1 4.4 4 1 1 5 5 5 1 HEAT-like repeat PPP4R2 PF09184.6 CCH60466.1 - 0.19 11.2 24.0 0.37 10.2 16.6 1.4 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 CCH60466.1 - 0.3 10.9 19.6 0.59 9.9 13.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 CCH60466.1 - 0.33 9.1 10.1 0.76 7.9 7.0 1.5 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 CCH60466.1 - 3.4 5.4 26.4 7 4.4 18.3 1.5 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 CCH60466.1 - 3.5 6.7 21.8 1 8.5 12.0 2.2 3 0 0 3 3 3 0 NOA36 protein Aminotran_4 PF01063.14 CCH60467.1 - 3.9e-15 55.9 0.0 5.2e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV Kdo PF06293.9 CCH60468.1 - 2.4e-08 33.2 0.0 3.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCH60468.1 - 3.3e-05 23.1 0.0 6.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCH60468.1 - 0.00053 19.7 0.5 0.38 10.4 0.7 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CCH60468.1 - 0.00081 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family DUF1679 PF07914.6 CCH60468.1 - 0.078 11.6 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) tRNA-synt_1g PF09334.6 CCH60469.1 - 5.2e-145 482.9 0.3 7.6e-145 482.4 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 CCH60469.1 - 1.9e-38 131.5 0.7 1.9e-38 131.5 0.5 2.0 3 0 0 3 3 3 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 CCH60469.1 - 1.3e-10 39.9 1.1 0.00018 19.6 0.0 3.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCH60469.1 - 0.00065 19.4 0.0 0.0018 18.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCH60469.1 - 0.019 14.1 0.0 0.062 12.4 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 CCH60470.1 - 3e-45 153.7 0.8 1.3e-44 151.6 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH60470.1 - 3e-22 78.2 0.0 6.1e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCH60470.1 - 1.6e-20 72.4 0.5 3.2e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCH60470.1 - 0.008 16.0 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CCH60470.1 - 0.011 15.1 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 CCH60470.1 - 0.065 13.3 1.3 0.33 11.1 0.7 2.4 2 1 0 2 2 2 0 AAA domain PhoD PF09423.5 CCH60471.1 - 2.5e-06 26.3 0.0 5.4e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase DUF3437 PF11919.3 CCH60473.1 - 0.28 10.9 1.5 0.62 9.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Pkinase PF00069.20 CCH60474.1 - 1.7e-48 165.0 2.4 3.8e-48 163.8 1.7 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60474.1 - 4.1e-24 85.0 2.4 2.9e-23 82.2 1.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCH60474.1 - 0.031 14.0 0.1 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCH60474.1 - 0.056 12.4 0.0 0.79 8.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like GTP_cyclohydroI PF01227.17 CCH60475.1 - 4.8e-75 250.7 0.2 5.8e-75 250.5 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CCH60475.1 - 2.6e-05 24.0 0.0 8.2e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein DnaJ_CXXCXGXG PF00684.14 CCH60476.1 - 0.057 13.4 1.1 0.14 12.2 0.8 1.5 1 0 0 1 1 1 0 DnaJ central domain CAF-1_p150 PF11600.3 CCH60476.1 - 3.6 6.9 36.2 0.025 13.9 15.9 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MAP7 PF05672.6 CCH60476.1 - 3.8 6.8 40.2 6 6.2 27.9 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family AAA PF00004.24 CCH60477.1 - 6.4e-54 181.7 0.0 1.1e-42 145.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCH60477.1 - 2.5e-07 30.8 1.1 1e-05 25.5 0.0 3.7 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 CCH60477.1 - 6.3e-07 28.9 0.0 0.00019 20.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 CCH60477.1 - 3.6e-06 27.0 0.0 1.6e-05 24.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCH60477.1 - 1.6e-05 25.6 0.1 0.0046 17.7 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CCH60477.1 - 2.1e-05 24.2 0.0 0.00068 19.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCH60477.1 - 6.3e-05 23.1 0.2 0.0029 17.7 0.1 3.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCH60477.1 - 0.00031 19.9 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ResIII PF04851.10 CCH60477.1 - 0.0012 18.7 0.1 0.014 15.2 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCH60477.1 - 0.0014 18.3 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 CCH60477.1 - 0.0017 18.4 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCH60477.1 - 0.0018 17.2 0.0 0.74 8.6 0.0 3.4 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 TIP49 PF06068.8 CCH60477.1 - 0.0026 16.5 0.0 0.022 13.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus Bromodomain PF00439.20 CCH60477.1 - 0.0038 17.1 0.0 0.013 15.4 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_33 PF13671.1 CCH60477.1 - 0.0087 15.9 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CCH60477.1 - 0.009 15.4 0.0 0.76 9.2 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 CCH60477.1 - 0.0098 15.3 0.0 0.043 13.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCH60477.1 - 0.015 15.2 0.2 0.25 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCH60477.1 - 0.019 15.0 0.0 0.085 13.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CCH60477.1 - 0.022 15.0 1.5 0.11 12.7 0.0 3.1 3 0 0 3 3 2 0 ABC transporter RuvB_N PF05496.7 CCH60477.1 - 0.029 13.4 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CCH60477.1 - 0.038 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CCH60477.1 - 0.054 13.0 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCH60477.1 - 0.11 12.7 0.0 0.11 12.7 0.0 5.0 5 0 0 5 5 5 0 AAA domain Amidase PF01425.16 CCH60478.1 - 8.2e-91 305.0 0.0 9.6e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.9 CCH60479.1 - 3.8e-13 49.0 14.5 4.7e-12 45.4 10.1 2.1 1 1 0 1 1 1 1 Dynamitin NPV_P10 PF05531.7 CCH60479.1 - 0.24 11.6 16.6 0.083 13.1 0.7 3.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Sec63 PF02889.11 CCH60480.1 - 1.2e-133 445.2 0.6 5.9e-92 308.2 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCH60480.1 - 4.3e-53 179.2 1.1 4.3e-28 97.9 0.4 4.4 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 CCH60480.1 - 3e-21 76.0 2.9 2.4e-10 40.5 0.3 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCH60480.1 - 1.4e-17 63.2 0.0 1.5e-07 31.1 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCH60480.1 - 1.1e-06 27.7 0.2 0.0043 15.8 0.1 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA PF00004.24 CCH60480.1 - 9.9e-06 25.7 3.2 0.13 12.4 0.0 4.4 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CCH60480.1 - 2.8e-05 23.4 0.0 0.016 14.4 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.12 CCH60480.1 - 0.00029 20.2 0.2 1.8 7.9 0.0 4.1 5 0 0 5 5 5 2 IstB-like ATP binding protein FANCI_S1-cap PF14674.1 CCH60480.1 - 0.012 15.6 1.1 40 4.3 0.0 4.7 5 0 0 5 5 5 0 FANCI solenoid 1 cap Zeta_toxin PF06414.7 CCH60480.1 - 0.029 13.4 0.0 4.7 6.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin DUF2361 PF10153.4 CCH60481.1 - 8.4e-34 116.1 12.1 8.4e-34 116.1 8.4 2.3 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Ribosomal_S2 PF00318.15 CCH60481.1 - 3.1 6.9 10.3 1.7 7.7 5.1 2.2 1 1 1 2 2 2 0 Ribosomal protein S2 DUF1762 PF08574.5 CCH60481.1 - 3.4 8.1 13.5 0.27 11.6 3.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1762) DUF2406 PF10295.4 CCH60482.1 - 8.9e-26 90.2 0.3 1.7e-25 89.3 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.16 CCH60483.1 - 5.8e-61 206.4 0.1 7.7e-61 206.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Phage_Treg PF04761.7 CCH60483.1 - 0.017 14.8 1.7 0.051 13.3 0.0 2.7 4 0 0 4 4 4 0 Lactococcus bacteriophage putative transcription regulator Peptidase_S10 PF00450.17 CCH60484.1 - 3e-128 428.5 2.3 3.6e-128 428.2 1.6 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCH60484.1 - 0.037 13.9 0.0 0.18 11.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3591 PF12157.3 CCH60486.1 - 1.7e-185 616.8 0.5 1.7e-185 616.8 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CCH60486.1 - 3.9e-06 26.4 1.1 9e-06 25.2 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Rtt102p PF09510.5 CCH60487.1 - 9.6e-08 32.0 6.4 9.6e-08 32.0 4.5 3.8 2 2 0 2 2 2 1 Rtt102p-like transcription regulator protein RNase_T PF00929.19 CCH60488.1 - 3.8e-27 95.5 0.0 8.7e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 Exonuclease DLIC PF05783.6 CCH60489.1 - 0.00026 19.7 0.1 0.00036 19.3 0.0 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) GATase_2 PF00310.16 CCH60490.1 - 1.6e-22 79.7 0.3 1e-16 60.6 0.0 2.7 2 1 1 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCH60490.1 - 2e-14 53.7 0.0 4.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CCH60490.1 - 1.7e-12 47.1 0.0 3.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 CCH60490.1 - 2e-11 43.6 0.0 3.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCH60490.1 - 0.00089 18.0 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Adap_comp_sub PF00928.16 CCH60490.1 - 0.087 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family ABC_membrane PF00664.18 CCH60491.1 - 7.5e-37 127.2 13.8 9.8e-37 126.8 9.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCH60491.1 - 7e-36 123.5 0.1 2.5e-35 121.7 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 CCH60491.1 - 2.3e-09 37.6 7.0 3.1e-05 24.1 0.0 4.2 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 CCH60491.1 - 3.6e-08 32.9 0.1 0.00045 19.5 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCH60491.1 - 3.8e-06 27.0 0.0 1.1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CCH60491.1 - 6.8e-05 22.3 0.2 0.00017 21.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CCH60491.1 - 0.00038 21.2 0.1 0.00093 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH60491.1 - 0.0022 18.1 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCH60491.1 - 0.0029 16.8 0.0 0.0066 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCH60491.1 - 0.0042 17.4 0.1 0.0042 17.4 0.1 3.7 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.1 CCH60491.1 - 0.0056 16.2 0.3 0.014 15.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_ATPase PF09818.4 CCH60491.1 - 0.0059 15.2 0.1 0.23 10.0 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_10 PF12846.2 CCH60491.1 - 0.0061 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ATP-synt_ab PF00006.20 CCH60491.1 - 0.0072 15.8 0.0 0.025 14.0 0.0 1.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 CCH60491.1 - 0.0094 15.8 0.4 0.051 13.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CCH60491.1 - 0.01 16.1 0.0 0.058 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CCH60491.1 - 0.013 14.4 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SE PF00437.15 CCH60491.1 - 0.018 13.9 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 CCH60491.1 - 0.029 13.9 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCH60491.1 - 0.052 13.2 0.0 0.65 9.7 0.0 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCH60491.1 - 0.067 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CCH60491.1 - 0.072 13.0 0.7 0.36 10.7 0.5 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 CCH60491.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA12 PF10443.4 CCH60492.1 - 1.3e-167 557.7 2.3 2.9e-167 556.5 0.9 1.9 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 CCH60492.1 - 4.7e-07 29.3 0.0 1.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 CCH60492.1 - 5.6e-05 22.9 0.4 0.00044 20.0 0.3 2.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 CCH60492.1 - 0.00073 19.4 1.5 0.0052 16.6 0.0 3.0 3 1 0 4 4 4 1 AAA domain DUF106 PF01956.11 CCH60492.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 RRM_5 PF13893.1 CCH60492.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.24 CCH60493.1 - 1e-54 185.4 2.3 1e-54 185.4 1.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CCH60493.1 - 6.2e-53 179.3 12.2 3e-51 173.8 2.9 3.4 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.3 CCH60493.1 - 5.3e-35 120.8 7.7 1.6e-34 119.2 0.6 3.6 4 1 1 5 5 5 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 CCH60493.1 - 4.8e-31 108.2 0.0 9.5e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.3 CCH60493.1 - 0.00064 19.9 1.8 0.081 13.2 0.2 3.7 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.18 CCH60493.1 - 0.0082 15.5 0.4 0.083 12.2 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin family SSPI PF14098.1 CCH60493.1 - 0.0092 15.8 0.3 1.7 8.6 0.0 3.3 3 0 0 3 3 3 1 Small, acid-soluble spore protein I CTP_transf_2 PF01467.21 CCH60494.1 - 5.2e-12 46.0 0.0 9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase MA3 PF02847.12 CCH60495.1 - 1.2e-22 79.6 0.4 1.2e-22 79.6 0.2 2.1 2 0 0 2 2 2 1 MA3 domain RSF PF14876.1 CCH60495.1 - 0.0027 16.5 0.9 0.0027 16.5 0.6 1.7 2 0 0 2 2 2 1 Respiratory growth transcriptional regulator Glyco_hydro_17 PF00332.13 CCH60496.1 - 1.8e-08 33.7 0.2 1.8e-08 33.7 0.2 2.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 AUX_IAA PF02309.11 CCH60496.1 - 0.45 10.2 5.6 0.72 9.5 3.9 1.4 1 0 0 1 1 1 0 AUX/IAA family CPSF100_C PF13299.1 CCH60496.1 - 1.7 8.8 10.9 3.8 7.6 7.6 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Lin-8 PF03353.10 CCH60496.1 - 6 6.0 12.5 8.5 5.5 8.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glucan_synthase PF02364.10 CCH60497.1 - 0 1247.9 35.7 0 1128.3 9.9 3.3 3 0 0 3 3 3 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCH60497.1 - 3.8e-36 123.5 1.6 1.1e-35 122.0 0.4 2.5 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Smac_DIABLO PF09057.5 CCH60497.1 - 0.16 11.0 0.1 0.29 10.2 0.1 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Glyco_hydro_72 PF03198.9 CCH60498.1 - 9.6e-144 478.1 13.1 1.3e-143 477.6 9.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CCH60498.1 - 1.7e-26 92.4 6.4 1.7e-26 92.4 4.4 2.7 3 0 0 3 3 3 1 X8 domain G-patch PF01585.18 CCH60499.1 - 3e-09 36.5 0.0 7.9e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 G-patch domain DUF936 PF06075.7 CCH60499.1 - 1.7e-05 24.0 23.0 1.7e-05 24.0 16.0 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) MIP-T3 PF10243.4 CCH60499.1 - 0.44 8.9 56.8 0.55 8.6 39.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 CCH60499.1 - 0.57 8.7 36.6 0.75 8.3 25.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF3435 PF11917.3 CCH60499.1 - 0.91 8.1 17.5 1.2 7.7 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Ycf1 PF05758.7 CCH60499.1 - 2.6 5.6 30.0 3.3 5.3 20.8 1.2 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 CCH60499.1 - 6.2 5.8 30.6 8.8 5.3 21.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SOBP PF15279.1 CCH60499.1 - 9.2 6.5 21.3 12 6.1 14.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein HEAT_EZ PF13513.1 CCH60500.1 - 3.4e-19 68.7 7.2 1.1e-06 28.9 0.0 8.0 8 1 2 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.1 CCH60500.1 - 1.3e-18 67.0 0.0 1e-08 35.3 0.0 5.0 3 1 1 4 4 4 4 HEAT repeats HEAT PF02985.17 CCH60500.1 - 2.6e-15 55.0 12.6 0.00039 20.2 0.0 9.9 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.2 CCH60500.1 - 1.7e-06 28.3 2.2 0.014 15.8 0.0 6.1 4 2 3 7 7 7 1 Vacuolar 14 Fab1-binding region ParcG PF10274.4 CCH60500.1 - 1.8e-05 24.7 7.9 0.00033 20.6 0.1 3.9 4 1 1 5 5 5 2 Parkin co-regulated protein DNA_alkylation PF08713.6 CCH60500.1 - 5e-05 22.9 0.0 0.0021 17.6 0.0 3.4 3 1 1 4 4 4 1 DNA alkylation repair enzyme Arm PF00514.18 CCH60500.1 - 5.8e-05 22.7 5.4 1.8 8.5 0.0 5.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CCH60500.1 - 0.00083 18.7 7.6 0.1 11.9 0.1 4.8 3 2 1 4 4 4 2 CLASP N terminal ABC_membrane PF00664.18 CCH60501.1 - 6.2e-62 209.4 31.5 5.2e-40 137.6 8.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCH60501.1 - 4.3e-46 156.6 3.6 2.9e-28 98.8 0.1 3.8 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CCH60501.1 - 3.5e-12 46.0 5.1 0.0044 16.2 0.2 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCH60501.1 - 1.6e-11 44.6 7.2 0.00013 22.0 0.2 5.5 3 2 0 4 4 4 2 AAA domain AAA_17 PF13207.1 CCH60501.1 - 3.8e-08 34.1 0.3 0.0042 17.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCH60501.1 - 3.1e-07 29.8 0.2 0.025 14.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 CCH60501.1 - 4.8e-07 30.1 3.1 0.027 14.7 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CCH60501.1 - 4e-06 26.3 0.0 0.00069 19.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCH60501.1 - 2.2e-05 23.6 0.2 0.039 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCH60501.1 - 2.3e-05 24.5 1.0 0.82 9.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.1 CCH60501.1 - 0.00012 21.7 0.3 1.4 8.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 CCH60501.1 - 0.00013 21.0 0.0 0.32 9.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 CCH60501.1 - 0.00016 22.1 0.1 1.5 9.3 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 CCH60501.1 - 0.00026 20.9 0.3 0.013 15.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCH60501.1 - 0.0006 19.8 0.6 0.07 13.1 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 CCH60501.1 - 0.0012 18.4 1.6 3.8 6.9 0.0 3.8 4 0 0 4 4 4 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCH60501.1 - 0.0018 17.7 0.2 0.13 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_14 PF13173.1 CCH60501.1 - 0.0021 17.9 0.5 2.9 7.7 0.0 3.4 2 1 1 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CCH60501.1 - 0.011 15.4 1.2 2.2 7.9 0.0 3.1 2 1 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 CCH60501.1 - 0.019 14.0 0.1 4.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 CCH60501.1 - 0.019 14.6 0.7 0.18 11.5 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 CCH60501.1 - 0.02 14.3 5.1 0.29 10.5 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 CCH60501.1 - 0.021 15.1 0.0 0.021 15.1 0.0 4.0 2 1 1 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCH60501.1 - 0.028 13.8 0.1 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 CCH60501.1 - 0.041 14.0 0.1 6.5 6.9 0.0 3.1 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 CCH60501.1 - 0.068 12.8 1.1 10 5.7 0.0 2.8 2 0 0 2 2 2 0 NTPase AAA_28 PF13521.1 CCH60501.1 - 0.074 13.0 2.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCH60501.1 - 0.094 12.3 0.3 0.73 9.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 CCH60501.1 - 0.098 11.4 0.1 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 CCH60501.1 - 0.46 10.2 12.0 1.2 8.9 0.0 4.2 4 0 0 4 4 4 0 Dynamin family eIF-3c_N PF05470.7 CCH60502.1 - 2.6e-153 511.2 28.8 1.7e-123 412.8 6.6 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CCH60502.1 - 1.6e-11 44.4 5.0 5.3e-11 42.7 1.6 3.3 2 1 0 2 2 2 1 PCI domain DUF1815 PF08844.5 CCH60502.1 - 0.04 13.5 0.2 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) Acetyltransf_4 PF13420.1 CCH60502.1 - 2.1 8.2 11.2 5.1 7.0 0.1 4.3 5 1 1 6 6 6 0 Acetyltransferase (GNAT) domain Glyco_hydro_17 PF00332.13 CCH60503.1 - 2.9e-72 243.3 1.9 3.4e-72 243.1 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Methyltrn_RNA_3 PF02598.12 CCH60504.1 - 1.6e-94 316.5 0.0 2.4e-94 315.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.9 CCH60505.1 - 2e-06 28.0 23.3 2e-06 28.0 16.2 2.9 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SURF4 PF02077.10 CCH60506.1 - 1.7e-101 339.0 13.9 2.1e-101 338.8 9.6 1.1 1 0 0 1 1 1 1 SURF4 family TcdB_N PF12918.2 CCH60506.1 - 0.024 14.6 0.6 0.024 14.6 0.4 1.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF1625 PF07787.7 CCH60506.1 - 0.11 11.7 4.2 0.23 10.6 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DnaJ PF00226.26 CCH60507.1 - 3.5e-15 55.4 0.3 3.5e-15 55.4 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain DUF2348 PF09807.4 CCH60508.1 - 0.032 13.3 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) DUF3336 PF11815.3 CCH60509.1 - 3.6e-31 107.6 0.2 6.5e-31 106.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCH60509.1 - 7.9e-08 32.4 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Proteasome PF00227.21 CCH60510.1 - 4.4e-43 146.7 0.0 5.3e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH60510.1 - 4.7e-12 44.9 0.1 1.1e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Telomere_Sde2_2 PF13297.1 CCH60510.1 - 0.07 12.4 0.2 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Telomere stability C-terminal RTA1 PF04479.8 CCH60511.1 - 3.4e-52 177.1 18.5 3.9e-52 176.9 12.8 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2556 PF10831.3 CCH60511.1 - 4 7.1 8.5 3.1 7.4 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2556) MpPF26 PF07666.6 CCH60511.1 - 8.9 6.2 13.4 0.11 12.4 1.3 2.8 3 0 0 3 3 3 0 M penetrans paralogue family 26 RTA1 PF04479.8 CCH60512.1 - 1.1e-62 211.4 16.3 1.1e-62 211.4 11.3 1.5 2 0 0 2 2 2 1 RTA1 like protein Orthoreo_P10 PF07204.6 CCH60512.1 - 0.0003 20.4 0.2 0.018 14.8 0.1 2.5 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 MFS_1 PF07690.11 CCH60513.1 - 1.7e-32 112.4 29.1 1.7e-32 112.4 20.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4010 PF13194.1 CCH60513.1 - 0.0045 16.3 1.3 0.08 12.2 1.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4010) DUF3589 PF12141.3 CCH60514.1 - 1.9e-88 296.9 1.3 1.5e-86 290.6 0.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3589 PF12141.3 CCH60515.1 - 1.1e-97 327.3 3.1 1.5e-95 320.3 2.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3589 PF12141.3 CCH60516.1 - 4.3e-96 322.1 5.2 2.5e-93 312.9 3.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) TEX33 PF15400.1 CCH60517.1 - 0.21 11.9 4.0 0.11 12.9 1.0 1.7 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family Mvb12 PF09452.5 CCH60517.1 - 0.99 9.6 4.7 2.5 8.3 0.6 3.0 2 2 1 3 3 3 0 ESCRT-I subunit Mvb12 DUF3589 PF12141.3 CCH60518.1 - 1.7e-68 231.1 4.6 4.7e-66 223.0 3.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3589 PF12141.3 CCH60519.1 - 2.2e-84 283.5 1.5 1.2e-52 178.8 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF3589) DUF3589 PF12141.3 CCH60520.1 - 5.5e-92 308.5 3.3 5.4e-56 189.8 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3589) DUF2463 PF09591.5 CCH60520.1 - 0.041 13.4 2.2 0.072 12.6 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Oxidored_FMN PF00724.15 CCH60521.1 - 5.1e-85 285.4 0.0 5.8e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2414 PF10309.4 CCH60521.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) DUF3589 PF12141.3 CCH60522.1 - 6.3e-94 314.9 5.7 1e-91 307.6 4.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF3589 PF12141.3 CCH60523.1 - 8.3e-06 24.3 10.5 0.00025 19.4 1.5 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3589) Med31 PF05669.7 CCH60523.1 - 0.029 14.1 0.6 0.071 12.8 0.4 1.6 1 0 0 1 1 1 0 SOH1 Asp PF00026.18 CCH60524.1 - 1.1e-70 238.3 1.1 3.2e-70 236.8 0.8 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH60524.1 - 4e-08 33.3 0.0 3e-07 30.5 0.0 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCH60524.1 - 0.0031 17.0 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CCH60524.1 - 0.035 14.5 0.6 33 5.0 0.0 3.6 3 0 0 3 3 3 0 Aspartyl protease PIR PF00399.14 CCH60525.1 - 4.9e-40 133.5 64.7 1.4e-08 33.7 2.7 6.2 5 1 1 6 6 6 5 Yeast PIR protein repeat Oxidored_FMN PF00724.15 CCH60526.1 - 6.4e-109 364.0 0.0 7.4e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF2401 PF10287.4 CCH60527.1 - 5.5e-63 212.5 0.1 7.1e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCH60527.1 - 5.2e-19 68.1 0.1 1.8e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) PS_Dcarbxylase PF02666.10 CCH60528.1 - 3.5e-72 241.9 0.0 5.3e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase bZIP_1 PF00170.16 CCH60529.1 - 3.6e-06 26.8 2.9 6.9e-06 25.9 2.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 CCH60529.1 - 0.0008 19.8 0.8 0.0051 17.3 0.1 2.7 1 1 1 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 CCH60529.1 - 0.0015 18.2 2.6 0.0015 18.2 1.8 1.8 2 0 0 2 2 2 1 Basic region leucine zipper Phage_T7_Capsid PF05396.6 CCH60529.1 - 0.17 12.0 1.3 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 Phage T7 capsid assembly protein GTP_EFTU PF00009.22 CCH60530.1 - 2.4e-52 177.1 0.0 4.6e-52 176.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCH60530.1 - 3.8e-13 49.1 0.0 1.1e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCH60530.1 - 2.1e-10 40.5 0.1 6.1e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CCH60530.1 - 2.2e-07 30.6 0.0 7.2e-07 28.9 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CCH60530.1 - 0.00015 21.3 0.6 0.0013 18.3 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G, domain IV Miro PF08477.8 CCH60530.1 - 0.057 13.9 0.1 0.62 10.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Ogr_Delta PF04606.7 CCH60531.1 - 0.0036 16.9 3.6 0.0045 16.6 0.0 2.1 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 CCH60531.1 - 0.1 12.5 1.7 0.83 9.6 0.3 2.2 2 0 0 2 2 2 0 Zinc ribbon domain IBR PF01485.16 CCH60531.1 - 0.2 11.5 3.2 0.6 10.0 2.2 1.8 1 1 0 1 1 1 0 IBR domain zf-C2H2 PF00096.21 CCH60531.1 - 0.7 10.3 3.0 0.96 9.9 0.0 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.20 CCH60532.1 - 1.1e-58 198.4 0.4 9.3e-40 136.4 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60532.1 - 1.3e-26 93.2 1.0 2.9e-20 72.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH60532.1 - 0.0022 17.0 0.1 0.0071 15.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCH60532.1 - 0.0066 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH60532.1 - 0.015 14.9 0.0 0.89 9.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Asparaginase PF00710.15 CCH60533.1 - 5.3e-10 38.6 3.8 1.6e-09 37.0 2.6 1.9 1 1 0 1 1 1 1 Asparaginase A_deaminase PF00962.17 CCH60534.1 - 6.3e-78 261.9 0.0 7.1e-78 261.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.20 CCH60535.1 - 9.6e-33 113.4 0.0 9.6e-33 113.4 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60535.1 - 1.1e-11 44.2 0.1 2.9e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase zf-AN1 PF01428.11 CCH60536.1 - 8.2e-12 44.8 11.7 1.4e-11 44.0 8.1 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DUF3774 PF12609.3 CCH60536.1 - 1.3 9.8 3.8 9.1 7.2 1.0 2.4 1 1 1 2 2 2 0 Wound-induced protein Pga1 PF10333.4 CCH60538.1 - 1.8e-15 57.0 10.3 3.8e-09 36.4 1.0 2.3 1 1 1 2 2 2 2 GPI-Mannosyltransferase II co-activator DUF2009 PF09418.5 CCH60539.1 - 1.6e-198 660.1 8.2 2.1e-198 659.7 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CCH60539.1 - 4.6e-07 29.6 6.9 8.3e-07 28.7 4.8 1.4 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 CCH60539.1 - 0.078 12.8 4.1 0.2 11.5 2.8 1.6 1 0 0 1 1 1 0 IBR domain PGA2 PF07543.7 CCH60540.1 - 3.7e-16 59.1 8.5 1.2e-10 41.3 0.8 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 DUF3959 PF13105.1 CCH60540.1 - 0.041 13.1 1.5 0.051 12.9 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) OSTbeta PF15048.1 CCH60540.1 - 0.092 12.8 0.4 0.092 12.8 0.2 2.0 1 1 1 2 2 2 0 Organic solute transporter subunit beta protein Ly49 PF08391.5 CCH60540.1 - 0.13 12.4 0.8 0.18 11.9 0.5 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region COX16 PF14138.1 CCH60540.1 - 0.32 11.1 3.9 0.7 10.1 2.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Vpu PF00558.14 CCH60540.1 - 0.55 9.8 4.3 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Vpu protein RNA_pol_3_Rpc31 PF11705.3 CCH60541.1 - 1.5e-64 218.1 16.3 1.6e-64 218.0 11.3 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 MtrH PF02007.13 CCH60541.1 - 0.067 12.1 0.2 0.095 11.6 0.1 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Fmp27_WPPW PF10359.4 CCH60541.1 - 0.72 8.1 7.5 0.24 9.7 0.1 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tho2 PF11262.3 CCH60542.1 - 9e-52 175.9 9.6 9e-52 175.9 6.7 5.2 4 1 0 4 4 4 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CCH60542.1 - 1.9e-23 82.0 3.8 2.5e-23 81.6 0.2 2.9 3 0 0 3 3 3 1 Transcription- and export-related complex subunit SF3b10 PF07189.6 CCH60543.1 - 2.1e-22 78.7 0.5 2.6e-22 78.4 0.3 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) IncA PF04156.9 CCH60543.1 - 0.37 10.3 3.6 0.52 9.8 2.5 1.2 1 0 0 1 1 1 0 IncA protein Nefa_Nip30_N PF10187.4 CCH60544.1 - 0.00015 21.8 14.3 0.00025 21.1 9.9 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 MAP7 PF05672.6 CCH60544.1 - 0.29 10.5 16.8 0.41 10.0 11.6 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family COX16 PF14138.1 CCH60544.1 - 4.8 7.4 8.6 7.1 6.8 5.2 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 NDT80_PhoG PF05224.7 CCH60545.1 - 7.6e-61 205.3 0.8 7.6e-61 205.3 0.6 2.3 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family FATC PF02260.15 CCH60545.1 - 0.14 11.6 0.1 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 FATC domain GNAT_acetyltr_2 PF13718.1 CCH60546.1 - 4.1e-81 270.9 0.0 7.4e-81 270.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CCH60546.1 - 1.4e-66 223.4 0.0 6.8e-66 221.2 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CCH60546.1 - 3.1e-40 135.7 0.1 1e-39 134.1 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CCH60546.1 - 3.1e-37 126.7 1.3 9.9e-37 125.1 0.9 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Sigma70_r4_2 PF08281.7 CCH60546.1 - 0.018 14.5 0.1 0.42 10.1 0.0 2.7 2 0 0 2 2 2 0 Sigma-70, region 4 DEAD PF00270.24 CCH60546.1 - 0.051 13.0 0.0 0.16 11.4 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_7 PF13508.1 CCH60546.1 - 0.082 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.8 CCH60547.1 - 6.4e-45 152.0 0.7 7.7e-45 151.7 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF506 PF04720.7 CCH60547.1 - 0.094 12.3 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) CRT-like PF08627.5 CCH60547.1 - 0.098 12.6 1.4 0.15 11.9 1.0 1.4 1 0 0 1 1 1 0 CRT-like PBP1_TM PF14812.1 CCH60547.1 - 0.95 9.8 8.0 1.6 9.0 5.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 CCH60547.1 - 1.5 9.0 9.1 1.7 8.8 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 CCH60547.1 - 2 7.9 11.3 3.4 7.1 7.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 CCH60547.1 - 2.5 7.6 7.4 3.7 7.1 5.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 CCH60547.1 - 4 7.2 6.4 7.3 6.3 4.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 CCH60547.1 - 8.2 5.0 15.9 11 4.6 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDP-OH_P_transf PF01066.16 CCH60548.1 - 2.9e-16 59.6 5.9 2.9e-16 59.6 4.1 2.4 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AAA_18 PF13238.1 CCH60549.1 - 1.9e-06 28.1 3.8 2.1e-05 24.8 1.3 2.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH60549.1 - 2.6e-05 25.0 3.1 0.0004 21.2 2.2 2.5 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CCH60549.1 - 0.0054 16.3 0.1 0.015 14.8 0.1 1.7 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 CCH60549.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 CCH60549.1 - 0.05 13.2 0.0 0.75 9.3 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 CCH60549.1 - 0.085 12.9 0.1 0.23 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CCH60549.1 - 0.13 11.9 0.1 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AD PF09793.4 CCH60550.1 - 4e-09 36.2 0.5 2.9e-08 33.4 0.1 2.4 2 1 0 2 2 2 1 Anticodon-binding domain CENP-O PF09496.5 CCH60550.1 - 0.029 14.6 0.3 0.043 14.0 0.2 1.3 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component UBACT PF02134.16 CCH60550.1 - 0.088 12.3 4.6 1.5 8.4 0.4 2.4 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein Lum_binding PF00677.12 CCH60550.1 - 0.12 12.2 0.3 0.12 12.2 0.2 2.3 2 0 0 2 2 2 0 Lumazine binding domain DUF3402 PF11882.3 CCH60551.1 - 7.9e-86 288.6 16.8 7.9e-86 288.6 11.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CCH60551.1 - 3.7e-53 180.3 7.5 3.7e-53 180.3 5.2 4.1 3 1 0 3 3 3 1 N1221-like protein PI3_PI4_kinase PF00454.22 CCH60552.1 - 3.3e-42 144.5 0.2 1.6e-41 142.3 0.1 2.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CCH60552.1 - 1.8e-23 82.9 9.1 1.8e-23 82.9 6.3 3.6 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CCH60552.1 - 1.5e-12 46.7 0.0 3.2e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 FATC domain Ribosomal_L14 PF00238.14 CCH60553.1 - 2.8e-32 111.0 0.0 3.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4_3 PF13920.1 CCH60554.1 - 5.4e-10 38.7 7.1 8.5e-10 38.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH60554.1 - 2.3e-09 36.9 9.0 3.7e-09 36.2 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH60554.1 - 6.3e-09 35.7 8.0 1.1e-08 34.8 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH60554.1 - 1.9e-08 33.8 7.4 3.4e-08 33.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH60554.1 - 3e-06 26.8 8.5 5.4e-06 26.0 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCH60554.1 - 6.7e-06 25.7 5.7 1.5e-05 24.6 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCH60554.1 - 0.00021 21.1 7.4 0.00039 20.2 5.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CCH60554.1 - 0.0066 16.2 3.7 0.01 15.6 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCH60554.1 - 0.029 14.4 4.7 0.057 13.5 3.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CCH60554.1 - 1.9 8.0 8.9 12 5.5 6.2 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CCH60554.1 - 3.1 7.4 7.9 8.6 6.0 5.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Afi1 PF07792.7 CCH60554.1 - 9.7 6.1 13.2 0.85 9.6 4.7 2.1 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PH PF00169.24 CCH60555.1 - 2.3e-13 50.2 0.4 1.6e-12 47.5 0.3 2.5 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 CCH60555.1 - 4.1e-11 42.0 0.0 1e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH60555.1 - 1e-08 34.6 0.0 2.4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 CCH60555.1 - 1.3e-05 24.9 0.5 3.8e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 CCH60555.1 - 0.087 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SAM_1 PF00536.25 CCH60555.1 - 0.39 10.9 1.3 0.49 10.5 0.1 1.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) TPR_11 PF13414.1 CCH60556.1 - 7.7e-30 102.3 16.0 2.7e-10 39.7 2.1 6.4 5 2 2 7 7 7 4 TPR repeat TPR_1 PF00515.23 CCH60556.1 - 3.9e-28 95.8 15.1 2.8e-09 36.1 0.6 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCH60556.1 - 5.9e-28 94.5 11.4 2.6e-07 30.0 0.2 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCH60556.1 - 2e-21 74.0 17.5 9.9e-06 24.9 0.2 8.5 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCH60556.1 - 2.5e-21 75.3 1.5 5.6e-07 29.4 0.1 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCH60556.1 - 2.7e-19 67.6 7.2 1.1e-07 31.5 0.3 7.1 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 CCH60556.1 - 1.2e-17 63.7 27.1 1e-06 28.7 1.5 5.8 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCH60556.1 - 1.9e-17 63.4 0.0 2.7e-08 34.2 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCH60556.1 - 1.1e-13 51.3 0.1 1.1e-05 25.7 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH60556.1 - 3e-12 45.3 0.1 0.028 14.2 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCH60556.1 - 2.5e-11 43.1 0.0 0.042 14.4 0.0 5.7 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCH60556.1 - 3.5e-08 33.3 15.3 0.07 13.6 0.1 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCH60556.1 - 5.6e-08 32.5 0.0 0.00062 19.5 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCH60556.1 - 5e-05 23.0 0.4 0.28 11.1 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCH60556.1 - 0.00017 20.7 0.1 0.26 10.2 0.2 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat Sel1 PF08238.7 CCH60556.1 - 0.011 16.3 4.7 27 5.5 0.0 4.5 4 0 0 4 4 3 0 Sel1 repeat Fis1_TPR_C PF14853.1 CCH60556.1 - 3.9 7.4 10.3 3.7 7.5 0.1 4.8 4 1 2 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Ank_4 PF13637.1 CCH60558.1 - 3.7e-09 36.8 5.1 0.00019 21.8 0.9 3.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCH60558.1 - 7.3e-09 35.8 1.3 1.8e-05 24.9 0.9 3.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCH60558.1 - 6.7e-08 32.5 6.1 0.0031 17.6 0.2 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCH60558.1 - 8.8e-07 28.4 7.2 0.00052 19.6 0.5 4.0 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 CCH60558.1 - 4.2e-06 26.3 1.0 4.2e-06 26.3 0.7 5.9 4 2 1 5 5 5 1 KilA-N domain Ank_3 PF13606.1 CCH60558.1 - 4.7e-06 26.3 5.4 0.017 15.3 0.2 4.2 4 0 0 4 4 4 2 Ankyrin repeat HEAT_EZ PF13513.1 CCH60559.1 - 2.4e-15 56.4 3.7 0.025 15.0 0.0 8.7 8 1 1 9 9 9 4 HEAT-like repeat HEAT PF02985.17 CCH60559.1 - 3.2e-13 48.5 0.6 0.011 15.7 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat IBN_N PF03810.14 CCH60559.1 - 1.2e-12 47.6 8.8 5.6e-08 32.5 0.6 5.1 3 1 1 4 4 4 2 Importin-beta N-terminal domain HEAT_2 PF13646.1 CCH60559.1 - 2.2e-10 40.6 8.6 0.069 13.4 0.2 7.0 5 3 4 9 9 9 6 HEAT repeats Vac14_Fab1_bd PF12755.2 CCH60559.1 - 3.3e-05 24.2 5.8 3 8.2 0.0 6.9 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CCH60559.1 - 5.3e-05 23.1 6.5 1.5 8.8 0.0 6.8 8 0 0 8 8 8 2 Rix1 complex component involved in 60S ribosome maturation ALG3 PF05208.8 CCH60560.1 - 1.6e-124 415.9 31.7 2e-124 415.5 21.9 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.6 CCH60561.1 - 3.4e-08 32.9 0.3 9.6e-08 31.5 0.2 1.8 1 0 0 1 1 1 1 LisH Cellulase-like PF12876.2 CCH60562.1 - 0.015 15.7 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 Sugar-binding cellulase-like GatB_N PF02934.10 CCH60563.1 - 3.6e-89 298.4 0.0 4.8e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CCH60563.1 - 4e-19 68.7 0.0 7.9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 GatB domain Nucleoporin_C PF03177.9 CCH60564.1 - 8e-111 371.3 32.2 8e-111 371.3 22.4 1.7 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCH60564.1 - 3.1e-105 352.3 11.5 3.1e-105 352.3 7.9 2.0 2 0 0 2 2 2 1 Nup133 N terminal like HSP70 PF00012.15 CCH60565.1 - 4.4e-268 890.2 6.0 5e-268 890.0 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH60565.1 - 6e-17 61.2 0.1 5.4e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCH60565.1 - 0.00034 20.2 0.0 0.00063 19.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CCH60565.1 - 0.01 14.7 0.8 0.11 11.2 0.2 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 CCH60565.1 - 0.042 13.1 0.0 5 6.3 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 CCH60565.1 - 0.069 12.2 0.3 0.31 10.1 0.2 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase AAR2 PF05282.6 CCH60566.1 - 9e-22 77.4 13.5 2.4e-21 76.0 9.4 1.6 1 1 0 1 1 1 1 AAR2 protein Post_transc_reg PF13797.1 CCH60566.1 - 0.18 11.4 3.8 1.9 8.1 0.1 3.3 3 0 0 3 3 3 0 Post-transcriptional regulator UQ_con PF00179.21 CCH60567.1 - 6.4e-28 96.9 0.1 9.8e-28 96.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCH60567.1 - 0.0052 16.6 0.4 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.1 CCH60567.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B Pribosyltran_N PF13793.1 CCH60568.1 - 4.4e-41 139.2 0.1 1.9e-38 130.7 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCH60568.1 - 5.2e-36 124.1 1.0 8.8e-30 103.8 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCH60568.1 - 2.9e-12 46.4 1.3 5.4e-12 45.5 0.4 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCH60568.1 - 0.005 16.0 0.1 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UCH PF00443.24 CCH60569.1 - 1.1e-67 228.0 27.4 1.1e-67 228.0 19.0 3.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH60569.1 - 2.1e-19 70.0 2.1 2.1e-19 70.0 1.4 5.0 2 2 1 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase Cytidylate_kin2 PF13189.1 CCH60569.1 - 0.001 19.0 0.0 0.0047 16.8 0.0 2.1 1 0 0 1 1 1 1 Cytidylate kinase-like family Zn_clus PF00172.13 CCH60570.1 - 2.1e-08 33.9 12.5 3.5e-08 33.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin PF00225.18 CCH60571.1 - 3.5e-100 334.9 12.4 3.5e-100 334.9 8.6 2.5 2 0 0 2 2 2 1 Kinesin motor domain zf-RING_2 PF13639.1 CCH60572.1 - 1.7e-07 30.9 9.4 2.9e-07 30.2 4.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCH60572.1 - 8.9e-07 28.9 4.6 2e-06 27.7 3.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CCH60572.1 - 2e-05 24.4 5.7 7.7e-05 22.5 4.0 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CCH60572.1 - 0.00037 20.2 1.7 0.00078 19.2 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CCH60572.1 - 0.026 14.5 6.2 0.056 13.4 4.3 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 CCH60572.1 - 0.064 13.3 8.2 0.23 11.5 5.7 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH60572.1 - 0.082 12.5 8.1 0.22 11.2 5.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH60572.1 - 0.15 11.7 6.7 4 7.1 4.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CCH60572.1 - 0.19 11.7 7.1 0.37 10.8 4.9 1.5 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 CCH60572.1 - 0.23 11.2 1.2 0.51 10.0 0.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-UDP PF14569.1 CCH60572.1 - 1.3 8.7 4.1 19 5.0 0.7 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger bZIP_1 PF00170.16 CCH60572.1 - 1.8 8.5 5.2 1.3 9.0 0.3 2.8 2 0 0 2 2 2 0 bZIP transcription factor zf-RING_4 PF14570.1 CCH60572.1 - 1.8 8.1 10.1 1.4 8.6 0.8 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain PHD PF00628.24 CCH60572.1 - 6.1 6.6 6.5 13 5.5 4.5 1.6 1 0 0 1 1 1 0 PHD-finger AMP-binding PF00501.23 CCH60573.1 - 3.4e-80 269.4 0.0 4.5e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Bac_rhodopsin PF01036.13 CCH60574.1 - 1.3e-48 165.2 17.3 2.1e-48 164.5 12.0 1.4 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Esterase PF00756.15 CCH60575.1 - 2.2e-49 168.1 0.0 2.8e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCH60575.1 - 4.9e-05 23.1 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCH60575.1 - 0.046 13.5 0.0 0.076 12.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family RAG2_PHD PF13341.1 CCH60575.1 - 0.055 13.4 0.6 3.8 7.5 0.2 2.5 2 0 0 2 2 2 0 RAG2 PHD domain Lipase_3 PF01764.20 CCH60575.1 - 0.058 12.9 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) ATX_III PF08098.6 CCH60575.1 - 0.063 13.1 0.3 0.2 11.5 0.2 1.9 1 0 0 1 1 1 0 Anemonia sulcata toxin III family PGAP1 PF07819.8 CCH60575.1 - 0.16 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Bac_rhodopsin PF01036.13 CCH60576.1 - 1.9e-44 151.6 16.7 2.2e-44 151.4 11.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Bac_rhodopsin PF01036.13 CCH60577.1 - 6.1e-46 156.5 18.1 7.6e-46 156.1 12.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCH60577.1 - 0.079 12.3 6.8 1.1 8.6 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cation_efflux PF01545.16 CCH60578.1 - 1.7e-78 263.5 4.2 2.3e-78 263.1 2.9 1.1 1 0 0 1 1 1 1 Cation efflux family NDUF_C2 PF06374.6 CCH60578.1 - 0.026 14.5 0.3 0.98 9.4 0.0 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF457 PF04307.9 CCH60578.1 - 0.13 11.6 0.1 0.13 11.6 0.1 2.3 2 1 1 3 3 3 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Epiglycanin_C PF14654.1 CCH60578.1 - 0.7 9.9 4.6 1.1 9.3 2.0 2.1 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Pheromone PF08015.6 CCH60578.1 - 2.5 8.9 6.6 6.8 7.6 0.4 2.9 3 0 0 3 3 3 0 Fungal mating-type pheromone CTP_transf_1 PF01148.15 CCH60580.1 - 1.5e-18 67.4 10.2 5e-16 59.1 3.1 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family Mito_carr PF00153.22 CCH60581.1 - 5.9e-28 96.4 6.7 3.3e-13 49.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4190 PF13828.1 CCH60582.1 - 0.044 13.3 0.4 7.2 6.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) ETRAMP PF09716.5 CCH60582.1 - 1.5 8.8 5.0 0.28 11.1 0.4 2.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Epimerase PF01370.16 CCH60583.1 - 2.2e-19 69.8 0.1 3e-19 69.4 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCH60583.1 - 1.6e-13 50.0 0.2 2.2e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCH60583.1 - 9.7e-10 37.7 0.2 2.7e-09 36.3 0.2 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCH60583.1 - 1.2e-09 38.3 0.2 5.2e-09 36.3 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCH60583.1 - 2.8e-08 33.3 0.1 2.8e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family Polysacc_synt_2 PF02719.10 CCH60583.1 - 8.6e-08 31.4 0.8 1.7e-07 30.4 0.3 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCH60583.1 - 8.1e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH60583.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 CCH60583.1 - 0.00022 20.2 0.6 0.0022 16.9 0.4 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 CCH60583.1 - 0.014 15.7 0.2 0.04 14.3 0.0 1.8 2 0 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 CCH60583.1 - 0.022 14.6 0.0 0.063 13.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_redisom_C PF08436.7 CCH60583.1 - 0.097 12.5 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Semialdhyde_dh PF01118.19 CCH60583.1 - 0.11 12.8 0.3 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 CCH60584.1 - 1.3e-19 70.1 50.0 1.6e-18 66.5 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MerE PF05052.7 CCH60584.1 - 0.095 12.6 0.2 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 MerE protein DUF4538 PF15061.1 CCH60584.1 - 0.12 11.7 0.2 1.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) MFS_1 PF07690.11 CCH60585.1 - 1.8e-20 72.9 26.2 1.8e-20 72.9 18.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 CCH60585.1 - 4.5e-08 31.9 9.1 4.5e-08 31.9 6.3 2.6 1 1 2 3 3 3 2 MFS/sugar transport protein DUF4551 PF15087.1 CCH60586.1 - 5.2 5.3 14.7 6 5.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF382 PF04037.8 CCH60587.1 - 4.1e-45 152.7 2.9 7.9e-45 151.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 CCH60587.1 - 1.1e-17 63.1 2.6 1.1e-17 63.1 1.8 1.8 2 0 0 2 2 2 1 PSP DUF1992 PF09350.5 CCH60587.1 - 0.053 13.3 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) YfmQ PF10787.4 CCH60587.1 - 0.081 12.2 0.2 0.2 11.0 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group DUF1151 PF06625.6 CCH60587.1 - 0.1 12.3 8.9 0.24 11.1 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SNF2_N PF00176.18 CCH60588.1 - 7.4e-82 274.4 0.7 2e-81 273.0 0.5 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCH60588.1 - 9.3e-43 144.7 4.6 9.3e-43 144.7 3.2 2.7 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 CCH60588.1 - 4e-34 117.4 12.5 4e-34 117.4 8.7 3.5 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CCH60588.1 - 9.1e-16 57.4 0.1 5.7e-15 54.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH60588.1 - 1.7e-06 27.6 0.0 4.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH60588.1 - 0.0039 17.3 0.1 0.031 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Myb_DNA-binding PF00249.26 CCH60588.1 - 0.035 14.1 0.0 0.17 11.9 0.0 2.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain RCC1 PF00415.13 CCH60589.1 - 1.6e-21 76.2 1.1 7.5e-09 35.6 0.0 5.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCH60589.1 - 1.2e-15 56.6 11.0 4.9e-08 32.3 1.4 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CCH60589.1 - 6e-09 35.8 2.6 1.4e-05 25.0 0.2 2.9 2 0 0 2 2 2 2 BTB/POZ domain GATase PF00117.23 CCH60590.1 - 6.6e-47 159.4 0.0 1e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CCH60590.1 - 1.8e-46 156.8 0.0 3.1e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 CCH60590.1 - 4.9e-07 29.4 0.1 1e-05 25.0 0.0 2.7 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 CCH60590.1 - 0.035 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Ank PF00023.25 CCH60590.1 - 0.042 13.6 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat DUF2620 PF10941.3 CCH60590.1 - 0.13 12.3 0.1 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2620 Leader_CPA1 PF08252.6 CCH60591.1 - 3e-10 39.1 2.0 3e-10 39.1 1.4 1.1 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide RGS PF00615.14 CCH60592.1 - 1.3e-05 25.3 1.0 0.0011 19.0 0.3 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain MBF1 PF08523.5 CCH60593.1 - 1.4e-25 89.0 1.7 1.4e-25 89.0 1.2 1.9 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CCH60593.1 - 1.6e-14 53.4 0.4 2.9e-14 52.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 CCH60593.1 - 8.2e-07 29.1 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CCH60593.1 - 2.4e-05 24.3 0.1 4.2e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 CCH60593.1 - 0.12 12.2 0.1 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_6 PF13516.1 CCH60594.1 - 2.7e-11 42.2 15.7 0.92 9.7 0.2 9.4 10 0 0 10 10 10 4 Leucine Rich repeat LRR_1 PF00560.28 CCH60594.1 - 2.6e-05 23.6 16.4 7.3 7.0 0.0 7.8 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.2 CCH60594.1 - 0.00022 20.7 31.4 0.13 11.9 0.3 7.1 5 3 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH60594.1 - 0.001 18.8 16.2 0.61 9.8 1.4 5.7 4 1 1 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 CCH60594.1 - 0.71 10.3 14.1 1e+02 3.8 0.1 7.2 8 0 0 8 8 8 0 Leucine rich repeat Myc_N PF01056.13 CCH60594.1 - 0.85 8.7 9.7 1.2 8.2 6.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 CCH60594.1 - 2.2 8.5 14.9 5.3 7.3 10.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CybS PF05328.7 CCH60595.1 - 2.2e-42 143.8 0.1 2.8e-42 143.4 0.1 1.1 1 0 0 1 1 1 1 CybS RNase_H PF00075.19 CCH60596.1 - 3.1e-26 92.2 0.7 8.2e-26 90.8 0.5 1.8 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 CCH60596.1 - 1e-24 86.2 4.6 9.2e-18 64.0 0.4 2.9 2 0 0 2 2 2 2 Caulimovirus viroplasmin Macin PF14865.1 CCH60596.1 - 0.72 9.9 4.7 3.6 7.7 0.1 3.1 3 0 0 3 3 3 0 Macin Membr_traf_MHD PF10540.4 CCH60597.1 - 7.1e-11 42.0 0.0 3.1e-10 39.9 0.0 2.2 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CCH60597.1 - 1e-08 34.9 0.0 2.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain SWIB PF02201.13 CCH60598.1 - 3.4e-23 81.1 0.2 9.7e-23 79.6 0.2 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Peptidase_A17 PF05380.8 CCH60598.1 - 0.026 14.3 0.4 0.36 10.6 0.2 2.1 1 1 1 2 2 2 0 Pao retrotransposon peptidase RRS1 PF04939.7 CCH60599.1 - 2.4e-64 215.7 4.7 2.7e-64 215.5 3.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.15 CCH60600.1 - 1.3e-13 51.1 10.5 1.3e-13 51.1 7.3 2.9 2 1 0 2 2 2 1 RhoGEF domain Uds1 PF15456.1 CCH60600.1 - 0.57 10.1 8.1 0.17 11.9 1.3 3.0 3 0 0 3 3 3 0 Up-regulated During Septation S10_plectin PF03501.10 CCH60601.1 - 1.2e-42 143.6 0.4 1.3e-42 143.5 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 CCH60601.1 - 0.0048 15.0 0.2 0.0053 14.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF505) PadR PF03551.9 CCH60601.1 - 0.008 15.9 0.2 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 Transcriptional regulator PadR-like family YjcQ PF09639.5 CCH60601.1 - 0.052 13.6 0.2 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 YjcQ protein Replic_Relax PF13814.1 CCH60601.1 - 0.061 13.1 0.2 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation tRNA-synt_1c_C PF03950.13 CCH60601.1 - 0.097 12.3 0.1 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain Mpv17_PMP22 PF04117.7 CCH60602.1 - 4.6e-22 77.4 1.0 4.6e-22 77.4 0.7 2.8 3 0 0 3 3 3 1 Mpv17 / PMP22 family P5-ATPase PF12409.3 CCH60603.1 - 1.9e-35 121.3 0.1 6.3e-35 119.6 0.1 2.0 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 CCH60603.1 - 5.1e-27 94.3 0.0 5.1e-27 94.3 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CCH60603.1 - 3e-24 86.2 0.1 5.4e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH60603.1 - 5.3e-13 49.8 0.1 2.4e-11 44.4 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH60603.1 - 1.5e-05 24.8 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCH60603.1 - 3.6e-05 23.1 0.0 9.5e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCH60603.1 - 0.045 13.3 2.1 2 7.9 0.0 3.6 4 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase S1 PF00575.18 CCH60604.1 - 6.5e-58 192.7 32.7 1.1e-11 44.6 0.0 10.0 10 0 0 10 10 10 8 S1 RNA binding domain TPR_19 PF14559.1 CCH60604.1 - 2.2e-08 34.3 0.1 0.0021 18.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH60604.1 - 6.2e-06 26.7 0.2 0.02 15.5 1.0 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCH60604.1 - 4.6e-05 23.6 1.8 3.3 8.5 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH60604.1 - 0.00013 21.8 1.1 0.11 12.5 0.2 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCH60604.1 - 0.015 14.9 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 TPR repeat Suf PF05843.9 CCH60604.1 - 0.019 14.7 0.1 0.0099 15.6 1.5 4.6 3 1 2 5 5 5 0 Suppressor of forked protein (Suf) TAFII55_N PF04658.8 CCH60606.1 - 1.2e-54 184.1 0.1 1.2e-54 184.1 0.1 2.8 3 1 0 3 3 3 1 TAFII55 protein conserved region SNF2_N PF00176.18 CCH60607.1 - 5.9e-84 281.3 1.2 5.9e-84 281.3 0.8 2.4 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CCH60607.1 - 1e-16 60.5 0.6 1e-16 60.5 0.4 2.4 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 CCH60607.1 - 1.8e-16 59.7 0.0 1.8e-16 59.7 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 CCH60607.1 - 6.6e-14 51.8 5.8 6.6e-14 51.8 4.0 4.1 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex adh_short PF00106.20 CCH60608.1 - 1.4e-31 109.6 0.0 1.8e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCH60608.1 - 1.6e-15 57.5 0.1 2.2e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCH60608.1 - 3e-09 36.7 0.0 4.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CCH60608.1 - 0.0056 15.8 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 CCH60608.1 - 0.0065 16.2 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 CCH60608.1 - 0.056 13.4 0.0 0.072 13.0 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Reovirus_M2 PF05993.7 CCH60608.1 - 0.075 10.8 0.0 0.11 10.2 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Thioredoxin PF00085.15 CCH60609.1 - 4.4e-22 77.7 1.5 1.2e-21 76.2 0.1 2.3 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 CCH60609.1 - 3.4e-06 26.9 9.2 0.0097 15.7 1.2 3.8 1 1 2 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCH60609.1 - 6.5e-05 22.9 0.0 6.5e-05 22.9 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCH60609.1 - 0.00012 22.2 3.0 0.00013 22.1 0.1 2.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCH60609.1 - 0.0013 18.7 0.1 0.0036 17.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CCH60609.1 - 0.0053 16.3 0.5 0.014 14.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Glutaredoxin PF00462.19 CCH60609.1 - 0.014 15.3 0.1 0.054 13.4 0.1 2.0 1 0 0 1 1 1 0 Glutaredoxin Redoxin PF08534.5 CCH60609.1 - 0.017 14.6 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Redoxin DSBA PF01323.15 CCH60609.1 - 0.12 11.9 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF947 PF06102.7 CCH60610.1 - 1.3e-37 129.2 28.4 1.3e-37 129.2 19.7 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF947) Rhodanese PF00581.15 CCH60611.1 - 1.9e-14 53.9 0.0 4.4e-14 52.8 0.0 1.6 1 1 1 2 2 2 1 Rhodanese-like domain TetR_N PF00440.18 CCH60611.1 - 0.15 11.7 1.1 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family His_Phos_1 PF00300.17 CCH60612.1 - 1.8e-30 106.1 0.0 2.2e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Jacalin PF01419.12 CCH60612.1 - 0.0097 15.7 1.5 1.1 9.1 0.2 2.4 2 0 0 2 2 2 2 Jacalin-like lectin domain Mre11_DNA_bind PF04152.9 CCH60613.1 - 1.1e-49 168.6 6.0 1.1e-49 168.6 4.2 2.5 2 1 1 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CCH60613.1 - 1.9e-23 82.9 1.6 3.4e-23 82.0 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH60613.1 - 6.4e-05 22.8 0.0 0.0002 21.2 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glutaredoxin2_C PF04399.8 CCH60613.1 - 0.21 11.1 6.4 0.028 13.9 1.1 2.0 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Phosducin PF02114.11 CCH60614.1 - 1.3e-07 30.5 6.6 0.00034 19.4 0.1 2.2 1 1 0 2 2 2 2 Phosducin UCH PF00443.24 CCH60615.1 - 3e-54 183.9 8.5 5.3e-54 183.1 5.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH60615.1 - 1.1e-29 103.7 7.5 2.1e-29 102.9 5.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCH60615.1 - 3.3e-12 46.3 12.5 3.3e-12 46.3 8.7 3.2 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein FSH1 PF03959.8 CCH60616.1 - 5.6e-59 199.1 0.0 6.3e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCH60616.1 - 2e-08 34.1 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCH60616.1 - 5.9e-07 29.1 0.0 2.1e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CCH60616.1 - 1.8e-05 24.7 0.0 0.02 14.7 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family M-factor PF03855.8 CCH60617.1 - 0.78 9.7 6.8 0.65 10.0 0.2 3.2 4 0 0 4 4 4 0 M-factor GATase PF00117.23 CCH60618.1 - 1.3e-40 138.9 0.0 2.1e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CCH60618.1 - 2.2e-40 136.2 0.0 4.8e-40 135.1 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 CCH60618.1 - 1.6e-08 34.2 0.0 6.1e-08 32.3 0.0 2.1 2 1 0 2 2 2 1 Peptidase C26 NAD_synthase PF02540.12 CCH60618.1 - 2.6e-08 33.0 0.0 7.2e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase PAPS_reduct PF01507.14 CCH60618.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 CCH60618.1 - 0.012 14.9 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 CCH60618.1 - 0.015 14.3 0.2 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase tRNA_Me_trans PF03054.11 CCH60618.1 - 0.025 13.1 0.1 0.052 12.1 0.1 1.5 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.9 CCH60618.1 - 0.048 13.1 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 CCH60618.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Pkinase PF00069.20 CCH60619.1 - 1.1e-41 142.6 3.0 9.8e-22 77.3 1.4 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60619.1 - 8.2e-11 41.4 1.1 1.6e-06 27.4 0.3 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.9 CCH60620.1 - 3.1e-123 410.7 6.5 3.7e-123 410.5 3.6 1.7 2 0 0 2 2 2 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 CCH60620.1 - 2.4e-05 23.4 0.0 6.3e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Tmemb_cc2 PF10267.4 CCH60620.1 - 1.1 7.7 9.1 1.6 7.2 6.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein BRO1 PF03097.13 CCH60621.1 - 1.5e-61 208.2 4.8 1.5e-61 208.2 3.3 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCH60621.1 - 1.5e-14 53.6 18.4 5.1e-10 38.7 2.9 3.0 3 1 0 3 3 3 2 ALIX V-shaped domain binding to HIV Gon7 PF08738.5 CCH60621.1 - 0.074 13.0 1.7 0.19 11.7 0.2 2.4 2 0 0 2 2 2 0 Gon7 family CotJB PF12652.2 CCH60621.1 - 0.087 12.9 1.2 20 5.3 0.2 3.3 2 1 1 3 3 3 0 CotJB protein IPPT PF01715.12 CCH60622.1 - 1.2e-87 293.1 1.1 1.5e-87 292.8 0.7 1.1 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 CCH60622.1 - 1.9e-06 28.6 0.6 8.7e-06 26.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 CCH60622.1 - 2.4e-05 23.6 0.2 0.00074 18.7 0.0 2.9 4 0 0 4 4 4 1 Isopentenyl transferase AAA_18 PF13238.1 CCH60622.1 - 0.00013 22.2 1.4 0.00058 20.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CCH60622.1 - 0.0093 15.8 0.1 0.035 13.9 0.0 2.1 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CCH60622.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 CCH60622.1 - 0.014 14.9 0.0 0.041 13.4 0.0 1.8 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 CCH60622.1 - 0.016 15.3 0.0 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCH60622.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCH60622.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 CCH60622.1 - 0.066 13.1 0.1 0.53 10.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCH60622.1 - 1.5 9.1 4.5 3.1 8.1 2.7 2.2 1 1 0 1 1 1 0 ABC transporter Abhydrolase_1 PF00561.15 CCH60623.1 - 4.7e-11 42.6 0.0 9.3e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCH60623.1 - 5.9e-09 36.1 0.0 8.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH60623.1 - 0.00018 21.2 0.0 0.00066 19.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 CCH60623.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF915 PF06028.6 CCH60623.1 - 0.0079 15.3 0.0 0.027 13.5 0.0 1.7 1 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CCH60623.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF4375 PF14300.1 CCH60623.1 - 0.066 13.2 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) MFS_1 PF07690.11 CCH60624.1 - 1.1e-22 80.3 42.1 3.9e-22 78.4 25.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Mtc PF03820.12 CCH60625.1 - 2.9e-114 380.8 0.1 3.2e-114 380.7 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier GHMP_kinases_N PF00288.21 CCH60626.1 - 6.2e-23 80.6 0.2 1.5e-22 79.3 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCH60626.1 - 1.3e-10 41.2 0.0 3.9e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal WD40 PF00400.27 CCH60627.1 - 1.2e-21 75.6 22.7 4.4e-06 26.3 0.7 7.0 5 2 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 CCH60627.1 - 0.054 11.6 5.3 0.38 8.8 3.7 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCH60627.1 - 0.058 12.1 3.4 1 8.0 0.1 2.3 1 1 1 2 2 2 0 Nup133 N terminal like Pkinase PF00069.20 CCH60628.1 - 6.5e-58 195.9 0.1 1.2e-57 195.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60628.1 - 1.4e-21 76.7 0.0 5.5e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH60628.1 - 0.00084 18.3 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH60628.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP_bind_1 PF03029.12 CCH60629.1 - 6.2e-74 248.5 2.7 9.8e-74 247.8 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCH60629.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.17 CCH60629.1 - 0.04 14.1 0.1 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 CCH60629.1 - 0.046 14.5 0.9 0.046 14.5 0.6 3.1 2 2 0 2 2 2 0 AAA domain CbiA PF01656.18 CCH60629.1 - 0.048 13.0 0.0 0.45 9.8 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_14 PF13173.1 CCH60629.1 - 0.081 12.8 2.0 0.26 11.1 0.0 2.6 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 CCH60629.1 - 0.083 12.8 0.1 0.43 10.5 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 CCH60629.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCH60629.1 - 0.99 9.7 9.6 1.3 9.3 0.1 3.1 3 1 0 3 3 3 0 AAA domain UbiA PF01040.13 CCH60630.1 - 5.8e-25 87.9 13.6 8.3e-25 87.4 9.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Hexapep PF00132.19 CCH60631.1 - 1.8e-05 24.0 3.8 0.00078 18.8 0.2 3.1 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCH60631.1 - 0.0005 20.1 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 CCH60631.1 - 0.0036 16.6 0.0 0.0094 15.2 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.7 CCH60631.1 - 0.015 13.9 0.2 0.03 12.9 0.1 1.5 1 0 0 1 1 1 0 L-fucokinase RXT2_N PF08595.6 CCH60631.1 - 1.1 9.0 16.1 4.9 6.9 0.3 2.8 2 0 0 2 2 2 0 RXT2-like, N-terminal AAA PF00004.24 CCH60632.1 - 9.1e-43 145.6 0.0 1.6e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCH60632.1 - 6e-07 29.6 0.2 4.6e-05 23.4 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCH60632.1 - 2.3e-06 27.3 0.1 6.7e-05 22.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCH60632.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCH60632.1 - 4.2e-05 23.6 0.1 0.0034 17.5 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCH60632.1 - 5.2e-05 22.4 0.0 9.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCH60632.1 - 0.00018 21.2 0.1 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCH60632.1 - 0.00053 20.7 0.6 0.0016 19.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCH60632.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CCH60632.1 - 0.0014 18.7 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase SPATA24 PF15175.1 CCH60632.1 - 0.0017 18.0 0.2 0.0035 17.0 0.1 1.5 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 TIP49 PF06068.8 CCH60632.1 - 0.0023 16.7 0.1 0.004 15.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CCH60632.1 - 0.0037 16.7 0.2 0.0087 15.4 0.2 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CCH60632.1 - 0.0046 16.3 0.6 0.034 13.5 0.3 2.2 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCH60632.1 - 0.0058 15.8 0.2 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCH60632.1 - 0.0079 16.0 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCH60632.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCH60632.1 - 0.0094 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCH60632.1 - 0.01 15.4 0.3 0.022 14.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCH60632.1 - 0.01 16.1 0.1 0.052 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CCH60632.1 - 0.035 13.2 1.2 0.094 11.8 0.0 2.3 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 CCH60632.1 - 0.039 13.1 0.2 0.077 12.2 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 CCH60632.1 - 0.045 12.8 1.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.12 CCH60632.1 - 0.077 11.8 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 CCH60632.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCH60632.1 - 0.1 12.2 0.1 0.33 10.5 0.0 1.8 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.1 CCH60632.1 - 0.14 11.7 1.7 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CCH60632.1 - 0.14 11.6 0.2 0.62 9.5 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain Fib_alpha PF08702.5 CCH60632.1 - 0.15 12.1 1.5 0.35 10.9 1.0 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CCH60632.1 - 0.23 9.2 0.5 0.32 8.8 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CCH60632.1 - 0.36 10.4 2.5 0.68 9.5 1.7 1.5 1 0 0 1 1 1 0 IncA protein PIGA PF08288.7 CCH60633.1 - 1.1e-45 153.9 2.5 3.9e-45 152.1 1.7 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCH60633.1 - 4e-31 107.7 0.0 7.6e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCH60633.1 - 1.8e-20 73.3 1.6 2.8e-20 72.7 0.4 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCH60633.1 - 1.9e-14 54.0 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCH60633.1 - 1.7e-13 50.9 0.0 4.2e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CCH60633.1 - 0.00059 19.6 0.9 0.0016 18.2 0.7 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CCH60633.1 - 0.027 14.7 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 TFR_dimer PF04253.10 CCH60634.1 - 3e-24 84.9 0.0 7.7e-24 83.6 0.0 1.8 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Methyltransf_15 PF09445.5 CCH60635.1 - 8e-56 188.0 0.5 8e-56 188.0 0.4 1.9 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CCH60635.1 - 2.3e-05 24.0 0.0 4.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 CCH60635.1 - 0.00012 21.7 0.4 0.00012 21.7 0.3 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH60635.1 - 0.00017 21.6 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCH60635.1 - 0.00069 19.0 0.1 0.0028 17.0 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 CCH60635.1 - 0.00069 20.1 0.0 0.0024 18.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH60635.1 - 0.005 17.1 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CCH60635.1 - 0.018 13.7 2.0 0.038 12.6 0.0 1.9 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase LepA_C PF06421.7 CCH60635.1 - 1.5 8.7 8.3 1.6 8.7 4.7 1.9 1 1 0 1 1 1 0 GTP-binding protein LepA C-terminus DUF3661 PF12400.3 CCH60636.1 - 1.1e-41 141.9 10.0 2.4e-41 140.8 6.9 1.6 1 0 0 1 1 1 1 Vaculolar membrane protein LOH1CR12 PF10158.4 CCH60637.1 - 0.076 12.8 1.1 0.15 11.8 0.7 1.4 1 0 0 1 1 1 0 Tumour suppressor protein HATPase_c_3 PF13589.1 CCH60638.1 - 6.2e-10 38.8 0.1 1.6e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCH60638.1 - 3.8e-06 26.5 0.1 8.4e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 CCH60638.1 - 2.2e-05 23.8 0.2 6.7e-05 22.3 0.2 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CCH60638.1 - 0.043 13.4 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 MutL C terminal dimerisation domain LNS2 PF08235.8 CCH60638.1 - 0.05 13.1 0.1 1.5 8.3 0.0 2.6 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Apc5 PF12862.2 CCH60639.1 - 7.4e-20 70.5 5.8 2.1e-19 69.1 4.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Clp1 PF06807.9 CCH60640.1 - 1.1e-09 38.4 0.1 1.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCH60640.1 - 1.2e-06 28.3 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CCH60640.1 - 0.0022 17.4 0.0 0.0051 16.3 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 CCH60640.1 - 0.0025 17.6 0.1 0.018 14.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 CCH60640.1 - 0.026 13.5 0.6 0.27 10.2 0.0 2.6 2 1 0 2 2 2 0 Septin MMR_HSR1 PF01926.18 CCH60640.1 - 0.033 14.1 0.2 0.19 11.6 0.1 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 CCH60640.1 - 0.041 13.8 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 CCH60640.1 - 0.097 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3293 PF11697.3 CCH60640.1 - 0.14 12.2 1.0 0.35 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) Syd PF07348.7 CCH60640.1 - 0.18 11.1 1.4 13 5.0 0.0 3.0 3 0 0 3 3 3 0 Syd protein (SUKH-2) CBM49 PF09478.5 CCH60640.1 - 0.33 11.0 3.5 25 5.0 0.0 3.7 3 1 1 4 4 4 0 Carbohydrate binding domain CBM49 Rhodanese PF00581.15 CCH60641.1 - 1.3e-17 64.1 0.0 4.1e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain HAD_2 PF13419.1 CCH60641.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Tup_N PF08581.5 CCH60642.1 - 3.7 7.7 6.2 2.2 8.5 0.6 2.2 2 0 0 2 2 2 0 Tup N-terminal DNA_pol_B PF00136.16 CCH60643.1 - 2.3e-86 290.4 0.0 3.4e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCH60643.1 - 2.7e-21 75.7 2.5 5.2e-11 41.9 0.2 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCH60643.1 - 4e-09 36.3 8.3 1e-08 35.0 5.8 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF4593 PF15263.1 CCH60643.1 - 0.59 10.0 0.0 1.1 9.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) rve PF00665.21 CCH60644.1 - 1.5e-14 54.1 0.0 2e-13 50.4 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain HIG_1_N PF04588.8 CCH60645.1 - 1.5e-19 69.4 3.0 2.5e-19 68.7 2.1 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Serglycin PF04360.7 CCH60645.1 - 0.0091 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Serglycin SprA-related PF12118.3 CCH60645.1 - 0.1 11.9 2.7 0.13 11.5 1.9 1.1 1 0 0 1 1 1 0 SprA-related family U79_P34 PF03064.11 CCH60645.1 - 0.69 9.3 5.5 0.85 9.0 3.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Homeobox PF00046.24 CCH60646.1 - 4.4e-15 55.0 9.3 9.1e-15 54.0 6.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCH60646.1 - 0.00071 19.2 0.7 0.0022 17.6 0.5 1.8 1 0 0 1 1 1 1 Homeobox KN domain VESA1_N PF12785.2 CCH60646.1 - 0.42 9.5 9.8 0.53 9.1 6.8 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Ribosomal_S13 PF00416.17 CCH60647.1 - 1.9e-41 140.8 2.2 2.2e-41 140.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCH60647.1 - 0.001 17.7 0.0 0.0011 17.5 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CCH60647.1 - 0.12 12.4 0.2 0.55 10.3 0.1 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix motif PP28 PF10252.4 CCH60647.1 - 0.18 11.8 0.4 0.18 11.8 0.3 1.6 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Ribosomal_S17e PF00833.13 CCH60648.1 - 2.3e-56 188.8 0.5 2.7e-56 188.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 ECM11 PF15463.1 CCH60649.1 - 1.5e-15 57.7 8.1 1.5e-15 57.7 5.6 3.1 1 1 1 2 2 2 1 Extracellular mutant protein 11 Nse5 PF08691.5 CCH60650.1 - 3.1e-86 289.9 34.9 4.5e-86 289.3 24.2 1.2 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 NAD4L PF06235.6 CCH60650.1 - 0.043 13.6 3.6 0.14 11.9 2.5 1.9 1 0 0 1 1 1 0 NADH dehydrogenase subunit 4L (NAD4L) DOT1 PF08123.8 CCH60651.1 - 2.3e-89 298.1 1.4 6.5e-89 296.6 1.0 1.8 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 CCH60651.1 - 0.012 14.6 0.0 0.029 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase UDG PF03167.14 CCH60652.1 - 3e-25 88.4 0.1 4.8e-25 87.7 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF294 PF03445.8 CCH60652.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 LRS4 PF10422.4 CCH60653.1 - 1e-05 25.0 37.0 0.0011 18.3 25.7 3.0 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 DUF972 PF06156.8 CCH60653.1 - 0.01 16.1 6.4 0.01 16.1 4.5 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 CCH60653.1 - 0.011 15.5 4.8 0.011 15.5 3.3 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Gemini_C4 PF01492.12 CCH60653.1 - 0.27 10.9 9.6 0.041 13.6 2.5 2.5 2 0 0 2 2 2 0 Geminivirus C4 protein GvpK PF05121.7 CCH60653.1 - 1.2 9.0 7.2 6.5 6.6 1.0 2.7 2 0 0 2 2 2 0 Gas vesicle protein K SlyX PF04102.7 CCH60653.1 - 3.1 8.2 15.5 0.19 12.1 1.1 3.6 2 1 1 3 3 3 0 SlyX NPV_P10 PF05531.7 CCH60653.1 - 8.5 6.7 15.7 2.8 8.2 0.8 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein OST3_OST6 PF04756.8 CCH60654.1 - 2.4e-15 56.4 11.5 4.2e-13 49.1 4.2 2.2 2 0 0 2 2 2 2 OST3 / OST6 family DUF953 PF06110.6 CCH60654.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) TPT PF03151.11 CCH60655.1 - 3.2e-08 33.3 27.5 5.9e-06 26.0 7.9 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 CCH60655.1 - 3.4e-07 30.3 36.6 7e-06 26.0 3.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCH60655.1 - 0.018 15.2 3.7 0.018 15.2 2.6 3.5 3 1 0 3 3 3 0 Multidrug resistance efflux transporter DUF4212 PF13937.1 CCH60655.1 - 2.2 8.3 10.3 20 5.2 0.5 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4212) UAA PF08449.6 CCH60655.1 - 4.5 6.1 20.9 0.17 10.7 10.4 1.6 2 0 0 2 2 2 0 UAA transporter family Peptidase_A2B PF12384.3 CCH60656.1 - 1.7e-10 40.4 0.0 2.9e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCH60656.1 - 5.4e-05 23.6 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CCH60656.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CCH60656.1 - 0.00075 19.4 0.2 0.0018 18.1 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCH60656.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 CCH60657.1 - 4e-10 39.8 0.0 7.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RWD PF05773.17 CCH60657.1 - 0.072 12.9 1.1 0.23 11.3 0.1 2.2 3 0 0 3 3 3 0 RWD domain Metallophos PF00149.23 CCH60659.1 - 4.7e-37 127.3 0.4 6.4e-37 126.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH60659.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain LCM PF04072.9 CCH60660.1 - 7.1e-24 84.3 0.0 9.4e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Acetyltransf_13 PF13880.1 CCH60660.1 - 0.12 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TAFII28 PF04719.9 CCH60661.1 - 2.7e-24 84.7 3.4 9.1e-24 83.0 1.0 2.6 3 0 0 3 3 3 1 hTAFII28-like protein conserved region Racemase_4 PF13615.1 CCH60661.1 - 0.00093 19.4 0.2 1.5 9.0 0.0 2.8 2 1 0 2 2 2 2 Putative alanine racemase DUF4014 PF13198.1 CCH60661.1 - 0.18 12.2 2.7 1.4 9.3 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) PIG-S PF10510.4 CCH60662.1 - 1.6e-107 360.3 11.6 2.5e-107 359.7 8.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein RRM_1 PF00076.17 CCH60663.1 - 1.1e-26 92.2 0.3 4.6e-17 61.4 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60663.1 - 4.1e-17 61.9 0.0 5.8e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60663.1 - 5e-12 45.4 0.0 8e-11 41.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CCH60663.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA binding domain Rad33 PF08730.5 CCH60664.1 - 7.7e-33 113.3 6.0 3e-30 104.9 4.2 2.1 1 1 0 1 1 1 1 Rad33 Spt5-NGN PF03439.8 CCH60665.1 - 7.5e-21 73.6 0.0 1.9e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 CCH60665.1 - 2.2e-17 63.4 11.3 2.2e-17 63.4 7.8 4.3 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 CCH60665.1 - 6.1e-14 51.1 13.5 0.0015 18.1 0.5 4.9 4 0 0 4 4 4 4 KOW motif DUF2118 PF09891.4 CCH60665.1 - 0.022 14.4 0.8 0.06 13.0 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Ribosomal_L33 PF00471.15 CCH60666.1 - 0.017 15.3 0.0 0.087 13.0 0.0 2.0 1 1 0 1 1 1 0 Ribosomal protein L33 DPM2 PF07297.7 CCH60667.1 - 6.3e-09 36.0 8.3 7.6e-09 35.7 5.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 CCH60667.1 - 0.013 15.1 9.3 0.015 14.9 6.5 1.0 1 0 0 1 1 1 0 PIG-P DPM3 PF08285.6 CCH60667.1 - 5.5 6.9 8.8 17 5.3 6.1 1.7 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FA_desaturase PF00487.19 CCH60667.1 - 5.6 6.3 7.2 6.4 6.1 5.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase PCI PF01399.22 CCH60668.1 - 1.8e-12 47.4 0.4 5.1e-12 46.0 0.3 1.8 1 0 0 1 1 1 1 PCI domain Spo0A_C PF08769.6 CCH60668.1 - 0.018 14.9 0.1 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal PCI_Csn8 PF10075.4 CCH60668.1 - 0.056 13.2 0.9 0.14 11.9 0.2 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 PX PF00787.19 CCH60669.1 - 4.5e-17 61.8 0.0 2.1e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 PX domain Dynein_light PF01221.13 CCH60670.1 - 2.4e-34 117.1 0.5 2.6e-34 117.0 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CCH60670.1 - 0.001 19.3 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Ground-like domain DUF1852 PF08908.6 CCH60670.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) DUF3646 PF12362.3 CCH60670.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Sterol_MT_C PF08498.5 CCH60671.1 - 3.8e-27 94.0 1.3 6e-27 93.3 0.9 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CCH60671.1 - 4.9e-20 71.8 0.0 9.9e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH60671.1 - 1.1e-17 64.0 0.0 1.9e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH60671.1 - 5.8e-14 52.1 0.0 9.6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCH60671.1 - 3.5e-13 49.2 0.6 4.7e-13 48.8 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CCH60671.1 - 3.6e-13 49.8 0.1 1.3e-12 48.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH60671.1 - 1.2e-12 48.0 0.0 3.5e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH60671.1 - 5.4e-10 39.8 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH60671.1 - 7.4e-10 38.3 0.0 1.6e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCH60671.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCH60671.1 - 0.00017 21.1 0.7 0.00065 19.2 0.2 1.8 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.13 CCH60671.1 - 0.0014 17.8 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 CCH60671.1 - 0.0024 17.0 0.1 0.0058 15.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 CCH60671.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 CCH60671.1 - 0.037 13.0 0.1 0.13 11.2 0.0 1.9 2 1 1 3 3 3 0 Putative methyltransferase DOT1 PF08123.8 CCH60671.1 - 0.07 12.4 0.1 0.19 11.0 0.0 1.7 1 1 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.9 CCH60671.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 CCH60671.1 - 0.11 11.5 0.0 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.14 CCH60671.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PAP1 PF08601.5 CCH60672.1 - 5.1e-34 118.5 30.3 4.9e-31 108.6 4.7 5.0 1 1 4 5 5 5 2 Transcription factor PAP1 bZIP_1 PF00170.16 CCH60672.1 - 1.3e-06 28.2 9.1 4.5e-06 26.5 6.3 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCH60672.1 - 0.0059 16.4 9.1 0.0059 16.4 6.3 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCH60672.1 - 0.11 12.7 13.0 0.43 10.9 7.3 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor ERM PF00769.14 CCH60672.1 - 1.8 8.0 14.3 0.018 14.5 4.0 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AMPKBI PF04739.10 CCH60673.1 - 7.9e-23 80.2 1.2 7.9e-23 80.2 0.8 4.1 4 1 0 4 4 4 1 5'-AMP-activated protein kinase beta subunit, interation domain Zn_clus PF00172.13 CCH60675.1 - 9.6e-08 31.8 7.5 1.7e-07 30.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IMS PF00817.15 CCH60676.1 - 1.6e-41 141.5 0.0 3.3e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCH60676.1 - 1.1e-07 31.7 0.1 2.6e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CCH60676.1 - 0.00068 19.5 0.1 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Ribosomal_L11_N PF03946.9 CCH60677.1 - 2.9e-17 61.8 1.3 6.6e-17 60.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCH60677.1 - 2.4e-11 43.5 1.1 4.9e-11 42.6 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Mak10 PF04112.8 CCH60678.1 - 1.4e-42 144.7 0.5 3.8e-42 143.3 0.4 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Myb_DNA-bind_4 PF13837.1 CCH60678.1 - 0.15 12.2 0.6 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain TPR_14 PF13428.1 CCH60679.1 - 3e-05 24.2 0.0 2.2 9.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCH60679.1 - 0.00061 19.3 0.1 5.7 6.6 0.0 4.2 4 0 0 4 4 4 2 TPR repeat TPR_15 PF13429.1 CCH60679.1 - 0.044 12.8 0.1 0.39 9.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCH60679.1 - 0.11 12.4 2.4 2.2 8.3 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCH60679.1 - 0.13 12.5 3.7 67 4.0 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCH60679.1 - 0.51 10.2 7.0 0.76 9.6 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat EXS PF03124.9 CCH60680.1 - 1.2e-54 185.6 30.0 1.4e-54 185.4 20.8 1.0 1 0 0 1 1 1 1 EXS family Nop25 PF09805.4 CCH60681.1 - 9.9e-34 116.3 17.2 9.9e-34 116.3 11.9 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Formyl_trans_N PF00551.14 CCH60682.1 - 9.2e-48 162.1 0.2 1.1e-47 161.9 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase UDG PF03167.14 CCH60682.1 - 0.042 13.3 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Proteasome PF00227.21 CCH60683.1 - 5.2e-46 156.3 0.0 7e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CCH60683.1 - 7.7e-11 41.0 0.2 1.8e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal ISN1 PF06437.6 CCH60684.1 - 5.4e-174 578.6 0.0 6.2e-174 578.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase ADH_zinc_N PF00107.21 CCH60685.1 - 7.5e-11 41.6 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH60685.1 - 0.00073 19.2 0.1 0.011 15.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ABC2_membrane PF01061.19 CCH60686.1 - 1.4e-84 282.4 50.8 1.9e-43 148.1 13.5 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCH60686.1 - 7.9e-41 139.5 0.1 5.8e-19 68.7 0.0 3.8 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.7 CCH60686.1 - 2.4e-36 123.5 17.0 7.8e-36 121.8 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCH60686.1 - 1.2e-16 60.5 0.2 3.1e-16 59.2 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCH60686.1 - 3.3e-08 33.1 0.0 5.4e-05 22.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCH60686.1 - 4.8e-07 29.9 0.2 4.7e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 CCH60686.1 - 1.5e-05 24.5 1.6 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCH60686.1 - 1.6e-05 24.8 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCH60686.1 - 5.9e-05 22.3 0.0 0.0025 16.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCH60686.1 - 7.9e-05 22.9 0.0 0.019 15.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH60686.1 - 0.00015 21.4 0.3 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain SMC_N PF02463.14 CCH60686.1 - 0.0003 20.0 0.0 0.011 14.9 0.0 3.0 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH60686.1 - 0.00049 19.5 0.9 0.0052 16.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCH60686.1 - 0.0018 18.3 0.1 0.64 10.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCH60686.1 - 0.0023 18.3 1.2 0.12 12.6 0.0 3.2 4 0 0 4 4 3 1 AAA domain UPF0079 PF02367.12 CCH60686.1 - 0.0034 16.9 0.5 0.78 9.3 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCH60686.1 - 0.0039 16.8 1.7 2.3 7.8 0.1 2.7 3 0 0 3 3 2 2 NACHT domain AAA_21 PF13304.1 CCH60686.1 - 0.0069 16.3 0.0 0.06 13.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCH60686.1 - 0.017 15.0 2.4 0.14 12.0 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCH60686.1 - 0.027 15.3 0.0 0.73 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCH60686.1 - 0.095 12.3 0.0 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 CCH60686.1 - 0.12 12.0 0.3 27 4.4 0.0 3.0 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.1 CCH60686.1 - 0.23 10.9 0.9 6.8 6.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCH60686.1 - 5.3 6.5 6.0 2.4 7.6 0.1 2.6 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L13 PF00572.13 CCH60687.1 - 3.7e-42 143.3 0.4 4.5e-42 143.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 SHS2_Rpb7-N PF03876.12 CCH60688.1 - 3.4e-16 59.1 0.0 6.6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCH60688.1 - 1.1e-15 57.4 0.1 1.8e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CCH60688.1 - 1.3e-06 28.6 0.0 2.6e-06 27.6 0.0 1.4 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 IU_nuc_hydro PF01156.14 CCH60689.1 - 9.8e-66 222.0 0.0 1.1e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ABC2_membrane PF01061.19 CCH60690.1 - 2.4e-88 294.7 50.1 4.8e-46 156.5 14.7 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 CCH60690.1 - 1.5e-44 149.8 2.9 9.6e-40 134.4 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CCH60690.1 - 2.9e-40 137.7 0.1 5.6e-19 68.8 0.0 3.5 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 CCH60690.1 - 1.9e-20 72.7 0.0 4.2e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCH60690.1 - 1.5e-08 34.2 0.0 3.4e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 CCH60690.1 - 1.5e-07 30.7 32.4 0.001 18.2 6.6 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 CCH60690.1 - 3.1e-07 30.5 0.1 5.2e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CCH60690.1 - 8e-06 25.7 0.1 0.028 14.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 CCH60690.1 - 1.4e-05 24.6 1.6 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CCH60690.1 - 5.2e-05 22.4 0.0 0.0019 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCH60690.1 - 5.3e-05 23.5 0.4 0.018 15.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CCH60690.1 - 0.00014 21.5 0.3 0.38 10.5 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_29 PF13555.1 CCH60690.1 - 0.00036 19.9 0.9 0.005 16.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CCH60690.1 - 0.00045 19.5 0.0 0.011 15.0 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCH60690.1 - 0.0014 18.7 0.2 0.62 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCH60690.1 - 0.0032 17.0 0.5 0.76 9.4 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CCH60690.1 - 0.0036 17.6 1.6 0.16 12.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CCH60690.1 - 0.0055 16.3 2.3 2.2 7.9 0.1 2.8 3 0 0 3 3 2 2 NACHT domain AAA_21 PF13304.1 CCH60690.1 - 0.0056 16.6 0.0 0.058 13.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH60690.1 - 0.021 15.6 0.0 0.71 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CCH60690.1 - 0.022 14.7 2.5 0.14 12.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCH60690.1 - 0.082 12.5 0.0 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 CCH60690.1 - 0.17 11.3 0.8 2.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CCH60690.1 - 0.22 10.8 0.4 18 4.6 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 CCH60690.1 - 0.23 11.0 0.9 6.6 6.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.18 CCH60691.1 - 3.9e-13 49.2 0.4 6.7e-13 48.4 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2956 PF11169.3 CCH60691.1 - 0.0077 16.1 0.3 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2956) Topoisom_bac PF01131.15 CCH60691.1 - 0.067 11.9 0.6 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 DNA topoisomerase Glyco_transf_22 PF03901.12 CCH60692.1 - 7.6e-72 242.5 40.9 9.8e-72 242.2 28.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2368 PF10166.4 CCH60692.1 - 0.096 12.2 0.2 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) AAA PF00004.24 CCH60693.1 - 2.8e-46 156.9 1.8 8.4e-46 155.4 0.0 2.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCH60693.1 - 1.5e-08 34.7 0.0 3.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCH60693.1 - 2.8e-08 33.5 0.1 1.4e-07 31.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH60693.1 - 3.6e-07 30.3 1.8 1.7e-06 28.1 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCH60693.1 - 8.5e-07 29.1 3.8 9.6e-05 22.5 0.3 3.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCH60693.1 - 8.6e-05 21.5 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CCH60693.1 - 0.00016 22.4 0.0 0.00064 20.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CCH60693.1 - 0.00024 20.9 0.0 0.00082 19.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCH60693.1 - 0.00036 19.6 0.0 0.00086 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CCH60693.1 - 0.001 18.7 0.1 0.0029 17.3 0.0 1.8 2 0 0 2 2 1 1 NTPase AAA_11 PF13086.1 CCH60693.1 - 0.0011 18.5 0.2 0.0077 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH60693.1 - 0.0013 18.4 0.1 0.0033 17.1 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CCH60693.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 CCH60693.1 - 0.0026 17.3 0.0 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCH60693.1 - 0.0027 17.3 0.0 0.0075 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CCH60693.1 - 0.0029 17.2 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCH60693.1 - 0.0033 16.5 0.0 0.0074 15.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 CCH60693.1 - 0.0035 16.8 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 CCH60693.1 - 0.0036 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCH60693.1 - 0.0036 16.7 1.0 0.1 12.0 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 CCH60693.1 - 0.004 17.1 0.0 0.009 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCH60693.1 - 0.0046 16.6 0.1 0.081 12.5 0.0 2.5 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 CCH60693.1 - 0.0054 15.9 0.1 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CCH60693.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 CCH60693.1 - 0.0067 15.8 0.2 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 CCH60693.1 - 0.013 14.2 0.0 0.024 13.3 0.0 1.6 1 1 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 CCH60693.1 - 0.014 15.6 0.0 0.045 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 CCH60693.1 - 0.021 14.5 4.4 0.13 11.9 0.0 3.2 3 1 1 4 4 3 0 Archaeal ATPase Bac_DnaA PF00308.13 CCH60693.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein NB-ARC PF00931.17 CCH60693.1 - 0.085 11.6 0.3 0.22 10.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 CCH60693.1 - 0.23 11.7 10.6 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain She9_MDM33 PF05546.6 CCH60694.1 - 5.9e-83 277.5 12.0 5.9e-83 277.5 8.3 2.3 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.15 CCH60694.1 - 0.0014 18.1 0.4 0.0032 16.9 0.2 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein G-patch_2 PF12656.2 CCH60695.1 - 9.8e-22 76.5 0.1 9.8e-22 76.5 0.0 2.1 2 1 1 3 3 3 1 DExH-box splicing factor binding site KH_1 PF00013.24 CCH60696.1 - 0.00022 20.8 0.6 0.00062 19.3 0.4 1.7 1 0 0 1 1 1 1 KH domain AAA PF00004.24 CCH60697.1 - 0.0026 17.9 0.0 0.0068 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_TK PF00693.13 CCH60697.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus TFIID-18kDa PF02269.11 CCH60698.1 - 6.5e-33 112.4 0.2 3.2e-32 110.2 0.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TPK_catalytic PF04263.11 CCH60699.1 - 2.4e-17 62.6 0.0 4.8e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CCH60699.1 - 2.4e-11 43.1 0.1 5.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Sec7 PF01369.15 CCH60700.1 - 2.1e-61 206.9 3.5 6.8e-61 205.2 2.4 1.9 1 0 0 1 1 1 1 Sec7 domain Rav1p_C PF12234.3 CCH60701.1 - 1.6e-221 736.8 12.7 8.3e-221 734.5 6.7 2.3 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.27 CCH60701.1 - 6.4e-06 25.8 2.1 1.2 9.1 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat SNF2_N PF00176.18 CCH60703.1 - 3.4e-75 252.6 0.2 8e-75 251.4 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH60703.1 - 1.8e-14 53.3 0.1 1.2e-13 50.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UCR_TM PF02921.9 CCH60704.1 - 1.4e-18 66.8 1.0 2.3e-18 66.1 0.7 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CCH60704.1 - 2.2e-18 65.6 0.1 3.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ribosomal_L7Ae PF01248.21 CCH60706.1 - 1.3e-26 91.8 0.1 1.6e-26 91.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCH60706.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 CCH60706.1 - 0.066 12.9 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain MULE PF10551.4 CCH60707.1 - 0.00018 21.6 0.4 0.00093 19.3 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain FA_hydroxylase PF04116.8 CCH60708.1 - 2.6e-16 60.0 19.1 2.6e-16 60.0 13.3 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Metallophos PF00149.23 CCH60709.1 - 2e-08 33.8 0.4 9.8e-08 31.6 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH60709.1 - 5.7e-05 22.9 0.0 0.00019 21.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Folliculin PF11704.3 CCH60710.1 - 7e-43 146.1 2.5 8.8e-43 145.7 1.7 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport BAH PF01426.13 CCH60711.1 - 5.7e-21 74.4 0.3 2.7e-20 72.3 0.1 2.3 3 0 0 3 3 3 1 BAH domain Bromodomain PF00439.20 CCH60711.1 - 5.8e-18 64.6 3.9 1.6e-11 43.9 0.4 3.1 2 0 0 2 2 2 2 Bromodomain Pox_Ag35 PF03286.9 CCH60711.1 - 9 5.7 14.9 0.19 11.2 0.5 2.9 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Flavodoxin_2 PF02525.12 CCH60712.1 - 9.6e-36 123.1 0.1 1.1e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCH60712.1 - 2.2e-10 40.2 0.0 3.3e-10 39.6 0.0 1.3 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCH60712.1 - 0.00021 20.6 0.4 0.00029 20.2 0.3 1.3 1 1 0 1 1 1 1 Flavodoxin PC-Esterase PF13839.1 CCH60712.1 - 0.099 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p AA_permease_2 PF13520.1 CCH60713.1 - 3.4e-86 289.4 49.5 4.4e-86 289.0 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCH60713.1 - 6.1e-19 67.7 45.2 8.2e-19 67.2 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 CCH60714.1 - 1.7e-46 158.5 2.8 2e-46 158.2 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60714.1 - 4.8e-26 91.3 0.0 9.2e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH60714.1 - 4.2e-07 29.2 0.0 7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MFS_Mycoplasma PF07672.8 CCH60714.1 - 0.29 10.2 1.0 0.53 9.4 0.0 1.8 2 0 0 2 2 2 0 Mycoplasma MFS transporter DUF2439 PF10382.4 CCH60715.1 - 8.8e-22 77.1 3.3 8.8e-22 77.1 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) KIAA1328 PF15369.1 CCH60715.1 - 0.0039 17.0 5.8 0.0053 16.6 4.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein KIAA1328 Trypan_PARP PF05887.6 CCH60715.1 - 0.21 11.4 8.7 0.36 10.6 6.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SelP_N PF04592.9 CCH60715.1 - 0.82 9.0 4.9 2.1 7.6 3.4 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Neisseria_TspB PF05616.8 CCH60715.1 - 9.3 4.4 12.7 16 3.7 8.8 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Kelch_4 PF13418.1 CCH60718.1 - 3.3e-12 45.9 0.4 6.4e-07 29.0 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CCH60718.1 - 2e-10 40.0 0.5 0.0014 18.1 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CCH60718.1 - 5.3e-10 39.1 0.1 1.5e-05 25.0 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CCH60718.1 - 1.4e-09 37.6 1.9 3.4e-05 23.8 0.0 4.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.1 CCH60718.1 - 0.00095 19.0 0.0 0.18 11.8 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CCH60718.1 - 0.0033 17.1 0.0 0.3 10.9 0.0 3.1 2 0 0 2 2 2 1 Kelch motif Hist_deacetyl PF00850.14 CCH60719.1 - 1.1e-79 267.9 0.0 1.5e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain COX6A PF02046.10 CCH60720.1 - 1e-34 118.9 0.9 1.1e-34 118.7 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.27 CCH60721.1 - 6.9e-19 66.9 0.2 0.0012 18.6 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_S26e PF01283.14 CCH60722.1 - 1.9e-50 169.8 9.0 2.3e-50 169.5 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 CCH60722.1 - 0.063 12.0 0.1 0.068 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) COX5B PF01215.14 CCH60723.1 - 2.3e-46 156.8 0.0 2.9e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb GCC2_GCC3 PF07699.8 CCH60723.1 - 0.047 13.2 0.3 0.075 12.6 0.2 1.4 1 0 0 1 1 1 0 GCC2 and GCC3 Transp_cyt_pur PF02133.10 CCH60724.1 - 1.1e-11 44.0 36.3 1.1e-11 44.0 25.2 2.1 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tim17 PF02466.14 CCH60724.1 - 0.27 11.2 5.4 0.12 12.4 0.3 2.5 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mnd1 PF03962.10 CCH60725.1 - 3.1e-39 134.6 14.0 1.1e-37 129.5 9.7 2.0 1 1 0 1 1 1 1 Mnd1 family PI3Ka PF00613.15 CCH60725.1 - 0.017 14.3 0.8 0.017 14.3 0.6 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) GAGA_bind PF06217.7 CCH60725.1 - 0.24 11.3 4.9 0.3 11.0 3.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family ArfGap PF01412.13 CCH60726.1 - 3.2e-30 104.2 0.2 3.2e-30 104.2 0.1 3.1 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf UPF0547 PF10571.4 CCH60726.1 - 0.014 15.1 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Kri1_C PF12936.2 CCH60726.1 - 0.025 14.4 0.2 0.13 12.2 0.1 2.2 1 0 0 1 1 1 0 KRI1-like family C-terminal Pkinase PF00069.20 CCH60727.1 - 1.6e-60 204.4 0.2 1.1e-59 201.6 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain DUF3543 PF12063.3 CCH60727.1 - 1.9e-51 174.5 13.6 2.4e-51 174.2 4.8 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase_Tyr PF07714.12 CCH60727.1 - 1.7e-44 151.8 0.0 3.1e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH60727.1 - 0.072 12.8 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 CCH60728.1 - 2.1e-54 184.3 1.7 6.6e-53 179.5 1.2 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60728.1 - 6.7e-26 90.9 1.8 3.6e-23 81.9 0.1 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH60728.1 - 1.6e-06 27.2 0.0 3.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Vfa1 PF08432.5 CCH60729.1 - 5.8e-43 147.0 3.2 6.8e-43 146.8 2.3 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Di19_C PF14571.1 CCH60729.1 - 0.013 15.8 2.3 0.32 11.3 0.1 2.4 1 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal PA26 PF04636.8 CCH60729.1 - 0.098 11.3 1.9 0.13 10.9 1.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SpoIIIAH PF12685.2 CCH60729.1 - 0.34 10.3 6.2 0.51 9.7 4.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF342 PF03961.8 CCH60729.1 - 3.5 5.9 6.6 3 6.1 3.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 CCH60729.1 - 4.2 7.7 11.7 1.7 9.0 5.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 CCH60729.1 - 5 6.6 6.5 1.2 8.6 2.4 1.5 2 0 0 2 2 2 0 IncA protein Sas10_Utp3 PF04000.10 CCH60730.1 - 3.5e-09 36.7 9.0 3.5e-09 36.7 6.2 2.6 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF506 PF04720.7 CCH60730.1 - 0.0053 16.4 2.8 0.0053 16.4 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF506) DNA_repr_REX1B PF14966.1 CCH60730.1 - 0.55 10.6 4.6 0.42 11.0 1.1 2.3 3 0 0 3 3 3 0 DNA repair REX1-B Ribosomal_S8e PF01201.17 CCH60731.1 - 2.1e-40 137.9 7.7 1.2e-39 135.4 5.3 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e YebF PF13995.1 CCH60731.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 YebF-like protein HPD PF05044.7 CCH60731.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Homeo-prospero domain PUF PF00806.14 CCH60732.1 - 4.5e-48 158.1 32.2 1.7e-08 33.5 0.9 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fungal_trans PF04082.13 CCH60734.1 - 1.2e-61 207.9 10.5 1.2e-61 207.9 7.3 2.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CCH60734.1 - 3.4e-09 36.4 9.7 0.00028 21.0 2.6 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH60734.1 - 2.9e-07 30.3 8.8 0.00047 20.2 2.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger GnHR_trans PF12369.3 CCH60734.1 - 1.8 9.0 9.3 7.2 7.1 0.5 3.9 3 0 0 3 3 3 0 Gonadotropin hormone receptor transmembrane region Lectin_leg-like PF03388.8 CCH60735.1 - 1.3e-40 138.9 0.0 2.2e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family ABC2_membrane_3 PF12698.2 CCH60735.1 - 0.18 10.8 7.3 0.26 10.2 5.1 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Snapin_Pallidin PF14712.1 CCH60735.1 - 0.59 10.4 6.5 0.49 10.7 1.6 2.4 1 1 1 2 2 2 0 Snapin/Pallidin DUF972 PF06156.8 CCH60735.1 - 2.7 8.4 10.3 0.48 10.7 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FCH PF00611.18 CCH60736.1 - 5.6e-14 52.0 0.5 5.6e-14 52.0 0.3 3.5 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 CCH60736.1 - 1.7e-10 40.4 0.1 5.1e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 CCH60736.1 - 6.5e-09 35.5 7.9 5.7e-06 26.0 0.1 3.6 3 0 0 3 3 3 2 RhoGAP domain PMM PF03332.8 CCH60738.1 - 2.8e-114 380.2 0.7 3.2e-114 380.0 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CCH60738.1 - 4e-05 23.3 0.0 0.00036 20.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 CCH60738.1 - 0.03 13.3 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) TMPIT PF07851.8 CCH60738.1 - 0.056 12.5 0.1 0.078 12.0 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Chordopox_A13L PF05961.6 CCH60738.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein zf-C2H2_jaz PF12171.3 CCH60739.1 - 1.2e-08 34.8 7.3 1.3e-08 34.7 3.5 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCH60739.1 - 0.00047 20.2 0.1 0.00079 19.4 0.1 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 CCH60739.1 - 0.07 12.6 1.5 0.12 11.9 1.0 1.3 1 0 0 1 1 1 0 U1 zinc finger zf-AD PF07776.10 CCH60739.1 - 0.073 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) Macoilin PF09726.4 CCH60740.1 - 7.5 4.6 17.2 13 3.8 11.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Cu-oxidase_3 PF07732.10 CCH60741.1 - 1.5e-45 153.6 1.5 4.4e-42 142.5 0.1 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 CCH60741.1 - 9.2e-39 132.1 9.3 5.8e-36 123.0 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 CCH60741.1 - 3.3e-15 56.3 1.9 5.3e-13 49.1 0.0 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 CCH60741.1 - 0.0001 22.1 0.0 1.7 8.5 0.0 3.7 4 0 0 4 4 4 2 Cupredoxin-like domain AATase PF07247.7 CCH60743.1 - 1.1e-49 169.3 8.3 1.3e-49 169.0 5.8 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CCH60743.1 - 9.3e-05 21.4 0.3 0.017 13.9 0.2 2.1 2 0 0 2 2 2 2 Condensation domain GTP_EFTU PF00009.22 CCH60744.1 - 4e-59 199.2 0.3 7.4e-59 198.3 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCH60744.1 - 2.3e-31 107.8 0.3 9.1e-31 105.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 CCH60744.1 - 3.7e-28 97.1 0.0 7.4e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCH60744.1 - 4e-21 74.6 0.0 1e-20 73.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCH60744.1 - 1.7e-13 50.4 0.4 4.3e-13 49.1 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CCH60744.1 - 0.0019 18.7 0.1 0.0047 17.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein SPC22 PF04573.7 CCH60745.1 - 2.9e-49 166.6 2.5 3.6e-49 166.3 1.7 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF788 PF05620.6 CCH60746.1 - 3.4e-44 150.6 0.1 3.9e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) DUF3115 PF11312.3 CCH60747.1 - 5.6e-94 314.5 0.1 6.8e-94 314.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) ABC_tran_2 PF12848.2 CCH60748.1 - 0.0078 16.0 0.7 0.0078 16.0 0.5 2.6 1 1 1 2 2 2 1 ABC transporter Nup88 PF10168.4 CCH60748.1 - 0.18 9.6 11.0 0.21 9.3 7.6 1.1 1 0 0 1 1 1 0 Nuclear pore component Glutaredoxin2_C PF04399.8 CCH60748.1 - 1.7 8.2 6.8 4 7.0 1.3 2.6 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain Arc_PepC PF06819.6 CCH60748.1 - 1.8 8.5 8.3 0.68 9.8 0.7 2.6 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain DUF148 PF02520.12 CCH60748.1 - 2.4 7.9 17.8 38 4.1 7.7 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 SlyX PF04102.7 CCH60748.1 - 3.3 8.1 10.0 5.9 7.3 0.2 3.4 1 1 2 3 3 3 0 SlyX FliD_N PF02465.13 CCH60748.1 - 4 7.8 10.5 0.19 12.1 1.7 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Med28 PF11594.3 CCH60748.1 - 4.1 7.6 18.5 0.61 10.3 2.7 3.2 1 1 2 3 3 3 0 Mediator complex subunit 28 TF_AP-2 PF03299.9 CCH60748.1 - 6.9 6.1 8.8 4.2 6.8 1.6 2.3 1 1 2 3 3 3 0 Transcription factor AP-2 IncA PF04156.9 CCH60748.1 - 7.7 6.0 14.2 4.5 6.8 0.8 2.1 1 1 1 2 2 2 0 IncA protein Ribosomal_L22e PF01776.12 CCH60749.1 - 1.6e-43 147.2 0.9 1.8e-43 147.0 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.7 CCH60750.1 - 1.7e-136 454.6 1.8 3.1e-136 453.8 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF726) bZIP_1 PF00170.16 CCH60751.1 - 1.2e-05 25.1 9.8 1.2e-05 25.1 6.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCH60751.1 - 8.3 6.3 23.0 0.16 11.8 10.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SHMT PF00464.14 CCH60752.1 - 1.1e-191 636.5 0.0 1.2e-191 636.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 CCH60752.1 - 3.1e-05 23.0 0.0 7.7e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCH60752.1 - 0.029 13.1 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCH60752.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_47 PF01532.15 CCH60753.1 - 2.9e-80 270.1 1.0 4.1e-80 269.6 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 CCH60753.1 - 0.048 11.9 0.0 5.1 5.2 0.0 2.9 3 1 0 3 3 3 0 Putative glycosyl hydrolase of unknown function (DUF1680) Pkinase PF00069.20 CCH60754.1 - 1.2e-25 90.1 0.2 2.7e-25 89.0 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60754.1 - 4.3e-15 55.4 0.0 5.9e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCH60754.1 - 0.002 17.4 0.3 0.0072 15.6 0.0 1.8 1 1 1 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 CCH60754.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FA_hydroxylase PF04116.8 CCH60755.1 - 7.7e-11 42.4 21.7 7.7e-11 42.4 15.0 3.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily ABC_tran PF00005.22 CCH60756.1 - 8.1e-17 61.8 0.1 2.5e-16 60.2 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCH60756.1 - 1.8e-08 34.6 0.5 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCH60756.1 - 7.8e-06 25.1 0.0 0.044 12.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CCH60756.1 - 0.00037 19.7 0.1 0.41 9.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH60756.1 - 0.00077 18.9 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CCH60756.1 - 0.011 15.1 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 CCH60756.1 - 0.022 15.0 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCH60756.1 - 0.029 15.1 0.3 0.055 14.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 CCH60756.1 - 0.04 11.2 0.1 0.051 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF258 PF03193.11 CCH60756.1 - 0.055 12.6 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCH60756.1 - 0.071 13.2 0.7 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCH60756.1 - 0.14 12.3 0.1 2.7 8.2 0.1 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CCH60756.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MutS_V PF00488.16 CCH60756.1 - 0.16 11.3 0.0 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 MutS domain V STE2 PF02116.10 CCH60757.1 - 2.8e-88 295.6 25.8 3.6e-88 295.3 17.9 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2976 PF11190.3 CCH60757.1 - 0.18 11.3 3.7 0.86 9.1 2.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) Av_adeno_fibre PF06536.6 CCH60757.1 - 5 6.8 8.8 0.2 11.4 0.2 2.9 4 0 0 4 4 4 0 Avian adenovirus fibre Fcf2 PF08698.6 CCH60759.1 - 2.5e-25 88.3 4.7 2.5e-25 88.3 3.3 2.3 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Sec63 PF02889.11 CCH60759.1 - 0.0027 16.9 1.7 0.0032 16.7 1.2 1.2 1 0 0 1 1 1 1 Sec63 Brl domain PRP1_N PF06424.7 CCH60759.1 - 0.62 10.3 17.7 0.025 14.8 6.2 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal CCDC92 PF14916.1 CCH60759.1 - 0.63 9.6 4.3 2.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Pyr_redox_dim PF02852.17 CCH60760.1 - 3.6e-42 142.8 0.1 1.1e-41 141.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CCH60760.1 - 4.7e-40 137.6 11.1 1.3e-38 132.9 7.7 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCH60760.1 - 1.9e-20 73.0 7.8 2.8e-17 62.8 0.1 3.7 3 1 1 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCH60760.1 - 5.1e-13 48.6 4.2 3.5e-12 45.9 0.4 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CCH60760.1 - 1.3e-12 47.5 1.0 7e-12 45.1 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCH60760.1 - 1.8e-09 37.9 0.2 1.3e-06 28.6 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCH60760.1 - 3.7e-09 36.4 5.0 0.00018 21.4 1.5 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCH60760.1 - 1.2e-07 30.9 1.4 1.2e-07 30.9 1.0 3.0 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 CCH60760.1 - 7.9e-06 25.0 11.2 0.0019 17.2 0.7 3.8 2 2 2 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CCH60760.1 - 7.9e-06 24.5 12.0 0.00024 19.7 0.5 4.1 3 1 1 4 4 4 1 HI0933-like protein Thi4 PF01946.12 CCH60760.1 - 2e-05 23.7 0.9 0.0031 16.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 CCH60760.1 - 0.0001 21.4 8.3 0.058 12.4 0.5 3.6 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 CCH60760.1 - 0.00024 20.1 0.8 0.8 8.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CCH60760.1 - 0.00028 20.5 0.4 0.081 12.4 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CCH60760.1 - 0.0087 15.7 0.1 0.0087 15.7 0.1 3.0 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CCH60760.1 - 0.017 14.2 0.1 0.064 12.3 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Rep_3 PF01051.16 CCH60760.1 - 0.17 11.4 5.9 5.7 6.4 2.1 2.8 1 1 1 2 2 2 0 Initiator Replication protein Lycopene_cycl PF05834.7 CCH60760.1 - 0.36 9.6 0.9 2.3 7.0 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Acetyltransf_1 PF00583.19 CCH60761.1 - 7.4e-14 51.5 0.0 1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCH60761.1 - 2.2e-11 43.7 0.0 3e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCH60761.1 - 8.4e-06 25.6 0.0 9.6e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mastoparan_2 PF08251.6 CCH60761.1 - 0.011 15.6 0.9 0.034 14.1 0.6 1.8 1 0 0 1 1 1 0 Mastoparan peptide Acetyltransf_10 PF13673.1 CCH60761.1 - 0.011 15.8 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCH60761.1 - 0.085 13.0 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 5_3_exonuc PF01367.15 CCH60761.1 - 0.12 12.6 0.1 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF2781 PF10914.3 CCH60762.1 - 1.7e-26 92.8 8.8 1.9e-26 92.6 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DnaJ PF00226.26 CCH60763.1 - 5.3e-23 80.5 7.1 8.4e-23 79.8 4.9 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCH60763.1 - 3.9e-20 71.5 0.7 1.1e-14 54.0 0.0 3.0 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCH60763.1 - 3.2e-11 43.1 18.7 5.4e-11 42.3 13.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCH60763.1 - 2.4 7.8 9.3 3.1 7.5 1.1 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CCH60763.1 - 3.6 8.0 9.8 11 6.3 6.8 1.8 1 1 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 CCH60763.1 - 6.6 6.4 12.8 0.7 9.5 5.3 2.0 1 1 1 2 2 2 0 Cytochrome c7 WW PF00397.21 CCH60765.1 - 1.1e-07 31.6 4.5 1.1e-07 31.6 3.1 1.9 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 CCH60765.1 - 2.2e-05 24.6 1.0 2.8e-05 24.2 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1183 PF06682.7 CCH60765.1 - 0.013 15.1 4.2 0.017 14.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) PAT1 PF09770.4 CCH60765.1 - 3.2 5.8 12.4 3 5.9 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 CCH60766.1 - 1e-46 155.2 18.1 6.7e-10 38.4 1.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CCH60766.1 - 5.2e-11 42.0 1.1 1.1e-10 41.0 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCH60766.1 - 1.5e-07 30.9 0.5 3.6e-07 29.6 0.3 1.7 1 0 0 1 1 1 1 F-box domain DUF3437 PF11919.3 CCH60767.1 - 2e-29 101.1 0.0 5.9e-29 99.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) DUF1546 PF07571.8 CCH60767.1 - 0.012 15.6 0.0 0.042 13.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) HEAT PF02985.17 CCH60767.1 - 0.021 14.8 0.0 1.4 9.2 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat Ras PF00071.17 CCH60768.1 - 1.5e-63 213.0 0.3 1.8e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH60768.1 - 1.1e-19 71.0 0.0 2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH60768.1 - 1.7e-18 66.4 0.2 2.1e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCH60768.1 - 8.4e-08 31.6 0.1 9.6e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH60768.1 - 2.9e-06 26.8 0.2 3.3e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCH60768.1 - 3.1e-06 26.5 0.1 5.9e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCH60768.1 - 1.7e-05 24.7 0.4 2.8e-05 24.0 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH60768.1 - 0.00094 18.4 0.1 0.015 14.5 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CCH60768.1 - 0.0085 16.2 0.0 0.027 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH60768.1 - 0.011 15.6 0.1 0.024 14.6 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CCH60768.1 - 0.015 14.5 0.1 0.025 13.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 G-alpha PF00503.15 CCH60768.1 - 0.019 13.6 0.4 0.41 9.2 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 CCH60768.1 - 0.019 14.4 0.1 0.064 12.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 CCH60768.1 - 0.027 13.9 0.0 0.1 12.0 0.0 1.9 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MCM PF00493.18 CCH60768.1 - 0.048 12.4 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AAA PF00004.24 CCH60768.1 - 0.063 13.4 0.0 0.53 10.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) VTC PF09359.5 CCH60769.1 - 5.8e-92 307.7 2.5 5.8e-92 307.7 1.7 2.7 2 1 0 2 2 2 1 VTC domain SPX PF03105.14 CCH60769.1 - 9e-23 81.4 23.1 1.7e-14 54.2 3.1 4.2 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 CCH60769.1 - 1.2e-10 41.4 0.3 2.7e-10 40.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Peptidase_C48 PF02902.14 CCH60770.1 - 7e-38 130.4 0.9 7e-38 130.4 0.7 2.1 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain DcpS_C PF11969.3 CCH60770.1 - 0.56 10.4 3.6 0.38 11.0 0.4 2.2 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Troponin PF00992.15 CCH60770.1 - 8 6.5 21.3 0.084 12.9 0.8 2.8 3 1 0 3 3 3 0 Troponin SIR2 PF02146.12 CCH60771.1 - 5.1e-54 182.7 0.0 1.7e-53 181.0 0.0 1.8 1 1 0 1 1 1 1 Sir2 family rve PF00665.21 CCH60772.1 - 1.3e-08 34.9 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1900 PF08954.6 CCH60772.1 - 0.035 13.6 0.1 0.067 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1900) Clat_adaptor_s PF01217.15 CCH60773.1 - 8.8e-16 57.9 2.5 1.9e-15 56.8 1.8 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AdoMet_MTase PF07757.8 CCH60774.1 - 1e-41 141.5 0.1 1.9e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 CCH60774.1 - 0.057 12.9 0.1 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain SUV3_C PF12513.3 CCH60775.1 - 2.7e-14 52.3 1.1 7.3e-14 50.9 0.8 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CCH60775.1 - 4.6e-13 48.8 0.0 9.6e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 CCH60776.1 - 1e-39 136.2 0.0 1.9e-38 132.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60776.1 - 1.2e-20 73.6 0.0 3.9e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH60776.1 - 4e-09 35.8 0.0 6.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CCH60776.1 - 0.0098 14.7 2.9 0.039 12.7 0.9 2.1 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Hormone_recep PF00104.25 CCH60776.1 - 0.035 13.2 0.1 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor APH PF01636.18 CCH60776.1 - 0.089 12.5 0.1 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sybindin PF04099.7 CCH60777.1 - 1.2e-31 109.3 0.1 5.9e-17 61.7 0.0 2.5 2 1 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.8 CCH60777.1 - 3.1e-08 33.5 0.0 9.1e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region MTHFR PF02219.12 CCH60779.1 - 8.6e-104 346.6 0.0 1.2e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.10 CCH60780.1 - 2.6e-26 92.0 0.1 1.1e-25 90.0 0.1 2.2 1 0 0 1 1 1 1 ERCC4 domain Totivirus_coat PF05518.6 CCH60780.1 - 0.036 11.9 0.0 0.052 11.3 0.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein DEAD PF00270.24 CCH60781.1 - 6.7e-46 155.8 0.4 5.3e-43 146.4 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH60781.1 - 7.8e-27 92.9 0.2 2.1e-26 91.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH60781.1 - 5.1e-05 23.1 0.0 0.00021 21.1 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCH60781.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_22 PF13401.1 CCH60781.1 - 0.27 11.3 4.1 0.16 12.1 0.1 2.6 3 0 0 3 3 3 0 AAA domain Fra10Ac1 PF09725.4 CCH60781.1 - 0.71 9.9 3.6 3.5 7.7 0.4 2.5 2 0 0 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 RRM_1 PF00076.17 CCH60782.1 - 0.00072 19.1 0.7 0.0025 17.4 0.0 2.3 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60782.1 - 0.003 17.3 0.3 0.012 15.4 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60782.1 - 0.0076 16.1 0.1 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CCH60782.1 - 0.015 14.9 3.0 0.034 13.8 2.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TPP_enzyme_M PF00205.17 CCH60785.1 - 2.7e-35 121.0 0.0 1.9e-34 118.3 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCH60785.1 - 5.8e-35 120.3 0.0 9.3e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCH60785.1 - 8.7e-14 51.3 0.0 2.8e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CCH60785.1 - 0.0099 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SKN1 PF03935.10 CCH60786.1 - 8.7e-251 832.3 5.8 1.3e-250 831.7 4.0 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF1438 PF07270.6 CCH60786.1 - 0.053 13.4 0.6 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Tom37_C PF11801.3 CCH60787.1 - 2.2 8.0 10.4 0.24 11.2 3.8 1.8 2 0 0 2 2 2 0 Tom37 C-terminal domain FAM176 PF14851.1 CCH60787.1 - 3.6 7.2 14.8 2.9 7.5 2.7 2.5 3 0 0 3 3 3 0 FAM176 family Neur_chan_memb PF02932.11 CCH60787.1 - 7.5 6.3 6.6 12 5.6 4.6 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MULE PF10551.4 CCH60788.1 - 1.2e-05 25.3 0.0 3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 CCH60788.1 - 3.1e-05 22.7 0.9 4.7e-05 22.1 0.6 1.2 1 0 0 1 1 1 1 Transposase, Mutator family GCR1_C PF12550.3 CCH60789.1 - 1.9e-14 53.2 0.0 5.1e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes MFS_1 PF07690.11 CCH60790.1 - 1e-32 113.2 40.0 2.4e-32 112.0 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH60790.1 - 2.8e-13 49.2 25.8 5.5e-13 48.2 17.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter SH3_9 PF14604.1 CCH60791.1 - 5.9e-14 51.3 0.1 1.4e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH60791.1 - 2.5e-12 46.0 0.1 4.5e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCH60791.1 - 4e-11 42.1 0.1 7.4e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF2076 PF09849.4 CCH60791.1 - 0.15 12.0 2.3 0.26 11.2 1.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4145 PF13643.1 CCH60791.1 - 0.17 11.7 0.1 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) PAT1 PF09770.4 CCH60791.1 - 2.4 6.2 16.8 3.1 5.9 11.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CCH60791.1 - 4.6 6.5 22.7 2.1 7.6 14.2 1.4 2 0 0 2 2 2 0 Vta1 like Proteasome PF00227.21 CCH60792.1 - 6.5e-58 195.1 0.1 8e-58 194.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH60792.1 - 2.3e-13 49.1 0.2 4.2e-13 48.3 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lipocalin_6 PF13944.1 CCH60792.1 - 0.048 13.7 2.4 1.7 8.8 1.0 2.2 2 0 0 2 2 2 0 Lipocalin-like domain FF PF01846.14 CCH60793.1 - 1.8e-11 43.8 1.9 4.8e-10 39.2 0.5 3.2 2 1 0 2 2 2 1 FF domain NESP55 PF06390.7 CCH60793.1 - 0.18 11.1 4.5 0.28 10.5 3.1 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Pet20 PF08692.5 CCH60794.1 - 2e-16 60.1 0.2 2.1e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Band_7 PF01145.20 CCH60795.1 - 8.8e-26 90.9 2.5 1.5e-25 90.1 1.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CCH60795.1 - 0.02 14.4 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family MARVEL PF01284.18 CCH60796.1 - 2.2e-27 95.6 3.8 2.8e-27 95.3 2.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain EI24 PF07264.6 CCH60796.1 - 0.01 15.2 2.7 0.019 14.3 1.9 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2721 PF11026.3 CCH60796.1 - 0.051 13.2 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) BAR_2 PF10455.4 CCH60798.1 - 3.1e-89 298.6 17.7 3.1e-89 298.6 12.3 1.4 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SCP2_2 PF13530.1 CCH60798.1 - 0.019 14.3 0.1 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 Sterol carrier protein domain DUF1509 PF07420.6 CCH60798.1 - 0.47 9.6 4.4 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) NRDE PF05742.7 CCH60799.1 - 1.1e-38 133.0 0.1 6.1e-38 130.7 0.1 1.8 1 1 0 1 1 1 1 NRDE protein Mis12 PF05859.7 CCH60799.1 - 0.046 13.5 0.1 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Mis12 protein MFS_1 PF07690.11 CCH60800.1 - 1.4e-24 86.5 28.1 2e-24 85.9 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily LPP20 PF02169.11 CCH60800.1 - 0.059 13.4 0.6 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 LPP20 lipoprotein SpoVAB PF13782.1 CCH60800.1 - 0.34 10.9 0.1 0.34 10.9 0.0 3.0 3 1 1 4 4 4 0 Stage V sporulation protein AB SSB PF00436.20 CCH60801.1 - 7e-20 70.8 0.1 8.5e-20 70.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family muHD PF10291.4 CCH60802.1 - 2.2e-70 236.7 0.0 5.8e-70 235.4 0.0 1.8 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF1720 PF08226.6 CCH60802.1 - 0.0025 17.8 0.8 0.008 16.2 0.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1720) Mannosyl_trans3 PF11051.3 CCH60803.1 - 2e-87 293.0 0.0 3.8e-87 292.0 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CCH60803.1 - 0.0011 18.4 0.2 0.0025 17.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ribosomal_L39 PF00832.15 CCH60804.1 - 6.3e-23 79.9 11.5 7.2e-23 79.7 8.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S8 PF00410.14 CCH60805.1 - 1.9e-26 92.4 0.1 2.5e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 CCH60806.1 - 2.4e-40 137.1 0.8 2.9e-40 136.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Beach PF02138.13 CCH60808.1 - 5.6e-108 360.4 0.6 5.6e-108 360.4 0.4 2.2 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 CCH60808.1 - 6.4e-11 42.0 0.0 5.1e-10 39.1 0.0 2.7 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH TPT PF03151.11 CCH60809.1 - 2.1e-28 98.8 8.8 2.1e-28 98.8 6.1 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CCH60809.1 - 0.0095 15.9 37.7 0.091 12.8 10.0 3.6 3 2 1 4 4 4 2 EamA-like transporter family DUF3278 PF11683.3 CCH60809.1 - 0.77 9.7 0.0 0.77 9.7 0.0 3.7 3 2 2 5 5 5 0 Protein of unknown function (DUF3278) AAA PF00004.24 CCH60810.1 - 6.6e-11 42.5 1.3 5.7e-10 39.5 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH60810.1 - 5.1e-10 39.6 0.0 1.6e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH60810.1 - 1.8e-06 28.0 0.0 0.00032 20.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CCH60810.1 - 5.5e-05 22.9 0.2 0.00017 21.3 0.0 1.8 1 1 1 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 CCH60810.1 - 8.1e-05 22.5 0.2 0.0042 16.9 0.1 3.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH60810.1 - 0.00071 19.2 0.0 0.0021 17.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Cdc6_C PF09079.6 CCH60810.1 - 0.0037 16.9 0.1 0.011 15.4 0.1 1.9 1 0 0 1 1 1 1 CDC6, C terminal AAA_18 PF13238.1 CCH60810.1 - 0.0067 16.7 0.2 0.67 10.2 0.0 3.2 3 1 0 3 3 2 1 AAA domain T2SE PF00437.15 CCH60810.1 - 0.041 12.7 0.0 0.071 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 CCH60810.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 CCH60810.1 - 0.12 11.9 7.0 0.07 12.7 2.4 2.3 2 1 0 2 2 2 0 AAA domain Aa_trans PF01490.13 CCH60811.1 - 7.8e-80 268.3 33.3 9.8e-80 268.0 23.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.7 CCH60812.1 - 5.9e-129 431.1 62.7 7e-129 430.9 43.5 1.0 1 0 0 1 1 1 1 Mpp10 protein CBF PF03914.12 CCH60813.1 - 3.3e-35 120.9 1.1 8e-35 119.7 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 CCH60813.1 - 7.3e-33 112.7 0.4 7.3e-33 112.7 0.3 3.8 3 1 0 3 3 3 2 Nucleolar complex-associated protein Candida_ALS_N PF11766.3 CCH60814.1 - 8.3e-67 224.6 6.2 8.3e-67 224.6 4.3 2.4 2 1 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.13 CCH60814.1 - 6.6e-39 131.4 100.8 5.9e-15 54.8 18.9 9.2 8 2 2 10 10 10 3 Flocculin repeat Candida_ALS_N PF11766.3 CCH60815.1 - 1.6e-64 217.2 3.5 2.5e-64 216.5 2.4 1.3 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.13 CCH60815.1 - 3.8e-05 23.4 26.3 0.00045 19.9 6.0 4.5 4 0 0 4 4 4 2 Flocculin repeat Adaptin_N PF01602.15 CCH60816.1 - 3.1e-95 319.5 21.2 3.8e-95 319.2 14.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCH60816.1 - 3.7e-08 33.5 0.0 0.0031 17.7 0.0 3.4 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 CCH60816.1 - 0.013 15.4 0.2 8.5 6.7 0.0 3.9 2 0 0 2 2 2 0 HEAT repeat UME PF08064.8 CCH60816.1 - 0.035 14.0 5.8 1.8 8.5 0.0 3.8 5 0 0 5 5 5 0 UME (NUC010) domain VHS PF00790.14 CCH60816.1 - 0.053 13.1 2.1 0.32 10.6 0.3 3.3 2 1 1 3 3 3 0 VHS domain Arm PF00514.18 CCH60816.1 - 0.15 11.9 0.6 38 4.3 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Response_reg PF00072.19 CCH60817.1 - 2.8e-19 69.1 0.1 9.7e-13 48.1 0.0 2.9 2 1 0 3 3 3 2 Response regulator receiver domain Cyt-b5 PF00173.23 CCH60818.1 - 5.7e-18 64.4 0.5 5.7e-18 64.4 0.3 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CCH60818.1 - 3.3e-08 33.9 19.2 3.3e-08 33.9 13.3 2.2 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Zds_C PF08632.5 CCH60819.1 - 1.8e-31 107.2 1.4 4.1e-31 106.1 1.0 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term MtrF PF09472.5 CCH60819.1 - 0.21 10.8 0.0 0.44 9.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Abi PF02517.11 CCH60820.1 - 2e-13 50.2 3.5 6.6e-13 48.6 2.4 1.9 1 0 0 1 1 1 1 CAAX protease self-immunity Ubie_methyltran PF01209.13 CCH60821.1 - 5.3e-99 330.0 1.0 6.3e-99 329.8 0.7 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CCH60821.1 - 1.2e-14 54.1 0.1 2.2e-14 53.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH60821.1 - 5.2e-13 49.3 0.0 9.6e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH60821.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH60821.1 - 1.5e-10 41.3 0.1 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH60821.1 - 2.2e-08 34.0 0.0 3.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH60821.1 - 3.2e-07 30.9 0.0 6.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH60821.1 - 0.0001 22.2 0.0 0.00024 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCH60821.1 - 0.00099 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CCH60821.1 - 0.0032 17.1 0.0 0.034 13.7 0.0 2.5 2 1 0 3 3 3 1 Hypothetical methyltransferase GidB PF02527.10 CCH60821.1 - 0.045 12.8 0.1 5.5 6.0 0.0 2.4 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G EutA PF06277.6 CCH60821.1 - 0.14 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA ADH_zinc_N PF00107.21 CCH60821.1 - 0.14 11.6 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Bul1_N PF04425.7 CCH60822.1 - 2.3e-157 524.0 2.8 2.3e-157 524.0 1.9 2.9 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCH60822.1 - 7.8e-96 320.4 16.2 7.8e-96 320.4 11.2 2.9 3 1 0 3 3 3 1 Bul1 C terminus ubiquitin PF00240.18 CCH60823.1 - 3.7e-21 74.2 0.2 6.2e-21 73.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCH60823.1 - 8.5e-10 38.1 0.2 1.4e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CCH60823.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 CCH60823.1 - 1.7e-05 25.0 0.1 3.8e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CCH60823.1 - 0.00025 20.9 0.3 0.0011 18.7 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCH60823.1 - 0.022 14.9 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain YukD PF08817.5 CCH60823.1 - 0.048 14.2 0.0 0.094 13.2 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PAS_4 PF08448.5 CCH60823.1 - 0.13 12.3 0.1 1.6 8.7 0.0 2.5 2 1 1 3 3 3 0 PAS fold Mucin PF01456.12 CCH60823.1 - 1.7 8.3 24.3 2.8 7.7 1.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 CCH60823.1 - 3.1 5.6 20.3 0.14 10.0 3.1 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 zf-CCHC PF00098.18 CCH60824.1 - 1.7e-05 24.5 3.3 2.8e-05 23.8 2.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C4pol PF14260.1 CCH60824.1 - 0.024 14.6 2.9 0.037 14.0 2.0 1.3 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-CCHC_2 PF13696.1 CCH60824.1 - 0.051 13.0 0.6 0.051 13.0 0.4 2.0 3 0 0 3 3 3 0 Zinc knuckle YgbA_NO PF11756.3 CCH60824.1 - 0.078 13.0 3.3 0.12 12.3 2.3 1.3 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter TSSC4 PF15264.1 CCH60824.1 - 0.081 13.3 1.0 0.26 11.7 0.2 1.9 1 1 1 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 zf-CCHC_3 PF13917.1 CCH60824.1 - 0.11 12.2 2.5 0.21 11.3 1.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 CCH60824.1 - 0.11 11.9 1.6 0.2 11.1 1.1 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger TAF8_C PF10406.4 CCH60825.1 - 6.6e-20 70.9 0.2 2e-19 69.3 0.1 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term NIF PF03031.13 CCH60826.1 - 2.7e-25 88.9 3.1 5.8e-24 84.5 0.0 3.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CCH60826.1 - 5.3e-12 45.7 0.6 6.5e-11 42.2 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCH60826.1 - 1.1e-07 31.6 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain ATP-synt_J PF04911.7 CCH60826.1 - 0.099 12.1 0.1 0.28 10.6 0.1 1.8 1 0 0 1 1 1 0 ATP synthase j chain MFS_1 PF07690.11 CCH60827.1 - 6.8e-33 113.8 58.4 7.5e-33 113.6 36.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF843 PF05814.6 CCH60827.1 - 0.037 13.8 1.0 0.15 11.9 0.7 2.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) DUF4131 PF13567.1 CCH60827.1 - 3.1 7.1 19.6 1.2 8.5 3.4 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 CCH60828.1 - 1.5e-36 125.9 58.2 5.3e-25 87.8 19.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCH60828.1 - 0.099 11.0 45.4 0.038 12.4 2.2 3.8 1 1 3 4 4 4 0 MFS/sugar transport protein DUF843 PF05814.6 CCH60828.1 - 0.42 10.4 3.2 0.74 9.6 1.0 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF4131 PF13567.1 CCH60828.1 - 0.5 9.7 22.9 1.4 8.3 0.7 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) Oxidored_FMN PF00724.15 CCH60829.1 - 3.9e-116 387.7 0.0 4.4e-116 387.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SinI PF08671.5 CCH60829.1 - 2.6 7.5 4.5 2.6 7.5 0.6 2.6 2 1 0 2 2 2 0 Anti-repressor SinI Exo_endo_phos PF03372.18 CCH60830.1 - 7.4e-26 91.5 0.1 9.7e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyr_redox_2 PF07992.9 CCH60832.1 - 2.6e-30 105.7 0.7 5.1e-19 68.9 0.0 3.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCH60832.1 - 7.7e-13 48.6 0.0 9.9e-10 38.6 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH60832.1 - 7.1e-09 36.0 0.1 0.0013 18.8 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCH60832.1 - 0.0031 16.5 0.5 4.6 6.0 0.0 3.6 2 2 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Cut8_C PF08559.5 CCH60832.1 - 0.031 14.0 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 Cut8 six-helix bundle Methyltransf_28 PF02636.12 CCH60832.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SQS_PSY PF00494.14 CCH60833.1 - 9.9e-36 123.3 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase OHA PF14418.1 CCH60833.1 - 0.044 13.2 0.6 11 5.6 0.0 3.0 2 1 1 3 3 3 0 OST-HTH Associated domain Oxidored_FMN PF00724.15 CCH60834.1 - 8.6e-70 235.3 0.0 9.8e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 CCH60835.1 - 2.8e-30 105.4 0.0 3.2e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PX PF00787.19 CCH60836.1 - 6.4e-18 64.5 3.7 1.5e-17 63.3 0.5 2.8 2 0 0 2 2 2 1 PX domain DUF1801 PF08818.6 CCH60836.1 - 0.12 12.4 2.9 0.25 11.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DU1801) EAP30 PF04157.11 CCH60836.1 - 0.17 10.9 7.0 0.036 13.2 0.9 2.6 2 1 1 3 3 3 0 EAP30/Vps36 family NPV_P10 PF05531.7 CCH60836.1 - 0.25 11.6 21.4 0.028 14.6 4.7 4.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Vps5 PF09325.5 CCH60836.1 - 1.1 8.4 22.3 0.46 9.6 6.0 2.5 1 1 0 2 2 2 0 Vps5 C terminal like CYTL1 PF15153.1 CCH60836.1 - 1.1 8.9 5.3 1.3 8.6 0.1 2.6 2 0 0 2 2 2 0 Cytokine-like protein 1 dCMP_cyt_deam_1 PF00383.17 CCH60837.1 - 8.4e-23 79.9 0.3 1.3e-22 79.3 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 CCH60837.1 - 0.00014 21.5 0.1 0.00026 20.6 0.1 1.4 2 0 0 2 2 2 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 CCH60837.1 - 0.0075 16.1 2.7 0.13 12.0 1.9 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 CCH60837.1 - 0.041 13.5 0.1 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Toxin-deaminase PF14424.1 CCH60837.1 - 0.046 13.6 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases HSP70 PF00012.15 CCH60838.1 - 5.9e-269 893.0 12.8 6.8e-269 892.8 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH60838.1 - 2e-18 66.0 2.7 2.9e-17 62.2 0.6 2.3 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CCH60838.1 - 7.5e-05 21.9 7.2 0.033 13.3 0.1 3.6 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 CCH60838.1 - 0.0078 15.5 0.0 0.074 12.3 0.0 2.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.5 CCH60838.1 - 0.012 14.4 1.4 0.098 11.4 0.7 2.3 1 1 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CCH60838.1 - 0.14 11.7 0.0 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CCH60838.1 - 0.79 9.5 10.3 0.46 10.3 0.8 3.6 3 2 0 3 3 3 0 Cell division protein FtsA FHA PF00498.21 CCH60839.1 - 8.5e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain RE_BstXI PF09552.5 CCH60839.1 - 0.18 10.7 2.2 0.29 10.1 1.5 1.3 1 0 0 1 1 1 0 BstXI restriction endonuclease DEAD PF00270.24 CCH60840.1 - 2.2e-43 147.6 0.4 1.3e-42 145.2 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCH60840.1 - 3.1e-25 87.4 0.1 8.1e-25 86.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCH60840.1 - 3.1e-22 78.2 0.0 6.8e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CCH60840.1 - 0.00019 21.4 0.0 0.00066 19.6 0.0 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain Cyclin_N PF00134.18 CCH60841.1 - 5.4e-09 35.6 3.1 1.1e-08 34.7 2.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Rep_Org_C PF06926.6 CCH60841.1 - 0.4 10.8 6.0 0.13 12.3 0.8 2.5 2 1 0 2 2 2 0 Putative replisome organiser protein C-terminus PPTA PF01239.17 CCH60843.1 - 3.8e-34 114.5 29.1 3.6e-07 29.2 0.3 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat HORMA PF02301.13 CCH60844.1 - 3.3e-32 111.6 0.0 3.8e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Vps53_N PF04100.7 CCH60845.1 - 4.7e-63 213.2 30.2 4.7e-63 213.2 20.9 2.1 2 0 0 2 2 2 1 Vps53-like, N-terminal KH_1 PF00013.24 CCH60847.1 - 6.3e-31 105.8 3.0 1.1e-09 37.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCH60847.1 - 6.3e-24 83.1 7.0 3.1e-07 29.8 0.0 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCH60847.1 - 1.1e-07 31.3 0.8 0.19 11.2 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCH60847.1 - 0.00023 20.7 0.9 0.36 10.4 0.0 3.8 3 0 0 3 3 3 1 KH domain Daxx PF03344.10 CCH60847.1 - 5.4 5.3 48.7 2 6.8 0.5 2.5 2 1 0 2 2 2 0 Daxx Family PQQ PF01011.16 CCH60849.1 - 0.095 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat CUE PF02845.11 CCH60850.1 - 7.6e-07 28.4 0.2 2.4e-06 26.9 0.1 2.0 1 0 0 1 1 1 1 CUE domain DUF3280 PF11684.3 CCH60850.1 - 0.005 17.0 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2380) Pox_MCEL PF03291.11 CCH60851.1 - 5.5e-96 321.3 0.0 9.8e-96 320.4 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 CCH60851.1 - 2.5e-07 30.5 0.0 4.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH60851.1 - 4.5e-07 30.2 0.1 2.1e-06 28.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH60851.1 - 8.8e-07 29.4 0.0 1.8e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH60851.1 - 1.8e-06 28.3 0.0 5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH60851.1 - 2.3e-06 27.8 0.0 4.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH60851.1 - 8.3e-06 25.4 0.0 1.8e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCH60851.1 - 0.0015 17.5 0.0 0.0032 16.4 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CCH60851.1 - 0.05 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 CCH60852.1 - 1e-39 135.7 0.0 3.5e-39 133.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH60852.1 - 1.3e-18 66.6 0.0 5.1e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CCH60852.1 - 0.00083 19.3 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain Vfa1 PF08432.5 CCH60853.1 - 1 9.3 23.3 1.2 9.0 16.1 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SAGA-Tad1 PF12767.2 CCH60853.1 - 4.1 6.9 15.3 4.9 6.7 10.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit YjgP_YjgQ PF03739.9 CCH60853.1 - 4.2 6.0 6.7 4.4 5.9 4.6 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family D5_N PF08706.6 CCH60853.1 - 4.8 7.2 7.1 7.1 6.7 4.9 1.5 1 1 0 1 1 1 0 D5 N terminal like DUF4634 PF15465.1 CCH60853.1 - 6.2 7.0 7.1 1.4 9.1 2.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4634) SprA-related PF12118.3 CCH60853.1 - 7 5.8 24.6 7.9 5.7 17.1 1.0 1 0 0 1 1 1 0 SprA-related family DUF3811 PF11656.3 CCH60853.1 - 7 6.7 17.4 0.14 12.2 6.0 2.2 1 1 1 2 2 2 0 YjbD family (DUF3811) PAS PF00989.19 CCH60855.1 - 9.2e-16 57.6 0.0 3.2e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 CCH60855.1 - 5.2e-05 23.0 8.6 9.9e-05 22.1 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 CCH60855.1 - 0.0051 17.1 0.0 0.055 13.8 0.0 2.4 3 0 0 3 3 3 1 PAS domain Mito_carr PF00153.22 CCH60856.1 - 1.9e-48 162.0 4.9 3.4e-19 68.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 CCH60856.1 - 0.088 12.5 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family FoP_duplication PF13865.1 CCH60857.1 - 6.7e-06 26.4 1.1 1.1e-05 25.7 0.8 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 CCH60857.1 - 0.00055 19.5 0.1 0.00083 18.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60857.1 - 0.0017 18.1 0.1 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60857.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PFU PF09070.6 CCH60858.1 - 4.9e-45 152.2 0.8 1.5e-44 150.7 0.6 1.9 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 CCH60858.1 - 1e-36 126.1 0.0 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 CCH60858.1 - 4.9e-34 114.9 5.2 1.1e-06 28.2 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCH60858.1 - 0.00018 21.2 3.0 0.64 9.8 0.0 3.8 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Proteasome_A_N PF10584.4 CCH60858.1 - 0.061 12.6 0.0 0.27 10.5 0.0 2.2 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Syja_N PF02383.13 CCH60859.1 - 5.7e-81 271.7 3.1 8.2e-81 271.2 2.2 1.2 1 0 0 1 1 1 1 SacI homology domain IGPS PF00218.16 CCH60860.1 - 3.8e-83 278.4 0.0 4.9e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 CCH60860.1 - 1.5e-56 190.8 0.0 2.4e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCH60860.1 - 9.9e-10 38.2 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 Peripla_BP_2 PF01497.13 CCH60860.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein NanE PF04131.9 CCH60860.1 - 0.0076 15.2 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.14 CCH60860.1 - 0.11 12.0 0.2 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiF PF00899.16 CCH60861.1 - 2e-50 170.1 0.2 8e-31 106.6 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CCH60861.1 - 1.4e-43 148.0 0.0 4.1e-43 146.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CCH60861.1 - 1.1e-30 105.0 5.9 1.4e-21 75.8 0.1 3.9 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCH60861.1 - 3.5e-26 90.3 0.5 8.4e-21 73.0 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site PEMT PF04191.8 CCH60862.1 - 1.5e-33 115.0 1.1 1.5e-33 115.0 0.7 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase HEAT_2 PF13646.1 CCH60864.1 - 8e-37 125.4 0.1 7.3e-18 64.6 0.0 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CCH60864.1 - 1.9e-18 64.9 0.0 0.00021 21.4 0.1 5.9 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.17 CCH60864.1 - 5.4e-12 44.7 1.2 0.079 13.0 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CCH60864.1 - 9.1e-08 32.3 0.5 0.0024 18.3 0.0 4.0 2 2 2 4 4 4 4 HEAT-like repeat Arm PF00514.18 CCH60864.1 - 0.073 12.9 0.0 52 3.8 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 CCH60864.1 - 0.15 12.0 0.2 16 5.5 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion FAT PF02259.18 CCH60866.1 - 2.3e-136 454.4 0.1 2.3e-136 454.4 0.1 2.6 3 0 0 3 3 3 1 FAT domain DUF3385 PF11865.3 CCH60866.1 - 5.3e-65 218.2 0.7 5.3e-65 218.2 0.5 5.3 4 1 1 5 5 5 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 CCH60866.1 - 5.9e-59 199.3 0.1 1.2e-58 198.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CCH60866.1 - 1.3e-42 143.9 0.6 1.3e-42 143.9 0.4 3.9 4 0 0 4 4 4 1 Rapamycin binding domain FATC PF02260.15 CCH60866.1 - 1.5e-17 62.6 0.2 3.9e-17 61.3 0.2 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CCH60866.1 - 8.7e-16 57.9 3.1 0.11 12.7 0.0 8.6 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 CCH60866.1 - 5.2e-10 39.5 0.3 7.5e-05 23.0 0.0 7.3 7 2 2 9 9 8 2 HEAT-like repeat HEAT PF02985.17 CCH60866.1 - 1.2e-06 28.0 1.5 0.044 13.8 0.0 7.0 8 0 0 8 8 8 1 HEAT repeat HrpB1_HrpK PF09613.5 CCH60866.1 - 0.0051 16.3 0.0 0.045 13.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.1 CCH60866.1 - 0.29 11.8 0.0 20 5.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 CCH60866.1 - 0.35 11.2 7.7 34 4.9 0.0 5.9 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Actin PF00022.14 CCH60867.1 - 8.4e-92 307.5 0.0 1.9e-91 306.4 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCH60867.1 - 1.3e-06 27.2 0.0 0.0026 16.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Cpn60_TCP1 PF00118.19 CCH60868.1 - 2.2e-144 481.6 4.6 2.5e-144 481.5 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 CCH60868.1 - 0.0031 17.1 1.5 2.7 7.6 0.1 2.9 2 1 0 2 2 2 2 Chloramphenicol phosphotransferase-like protein Hydrolase_like2 PF13246.1 CCH60868.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit AP_endonuc_2 PF01261.19 CCH60868.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TFIIS_C PF01096.13 CCH60869.1 - 8.4e-18 63.7 8.2 9.4e-18 63.5 1.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCH60869.1 - 1e-11 44.2 10.0 6.4e-10 38.5 0.8 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 CCH60869.1 - 0.00011 22.3 6.4 0.0026 17.9 0.3 2.6 2 1 0 2 2 2 1 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 CCH60869.1 - 0.0006 19.2 14.2 0.15 11.5 0.1 3.9 3 1 1 4 4 4 2 zinc-ribbon domain DZR PF12773.2 CCH60869.1 - 0.0015 18.2 8.9 0.07 12.9 0.3 3.0 2 1 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 CCH60869.1 - 0.0026 17.5 4.1 0.024 14.4 0.6 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CCH60869.1 - 0.0065 15.6 11.2 1.3 8.3 0.2 4.2 4 0 0 4 4 4 1 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CCH60869.1 - 0.008 15.4 10.5 0.025 13.8 2.0 2.8 2 2 0 2 2 2 1 TFIIB zinc-binding Ogr_Delta PF04606.7 CCH60869.1 - 0.016 14.8 5.6 0.061 12.9 1.2 2.7 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Mu-like_Com PF10122.4 CCH60869.1 - 0.023 13.7 1.4 1.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.1 CCH60869.1 - 0.031 13.8 11.2 0.94 9.1 0.6 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Terminase_GpA PF05876.7 CCH60869.1 - 0.031 12.6 1.4 0.043 12.1 0.3 1.6 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) Zn-ribbon_8 PF09723.5 CCH60869.1 - 0.041 13.8 13.9 1.8 8.5 0.1 3.7 4 0 0 4 4 3 0 Zinc ribbon domain zf-C3HC4_3 PF13920.1 CCH60869.1 - 0.053 13.2 3.1 2.3 7.9 0.2 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-TFIIB PF13453.1 CCH60869.1 - 0.065 12.4 0.8 0.065 12.4 0.5 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-DNA_Pol PF08996.5 CCH60869.1 - 0.088 12.1 5.6 0.18 11.1 0.5 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF2387 PF09526.5 CCH60869.1 - 0.12 12.3 0.2 0.12 12.3 0.1 2.6 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF2072 PF09845.4 CCH60869.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.9 1 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) zinc_ribbon_4 PF13717.1 CCH60869.1 - 0.16 11.7 13.9 0.8 9.4 0.6 3.5 4 0 0 4 4 3 0 zinc-ribbon domain Nop10p PF04135.7 CCH60869.1 - 0.17 11.6 2.3 0.18 11.5 0.2 2.1 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family CpXC PF14353.1 CCH60869.1 - 0.32 10.9 7.2 1 9.3 0.1 3.1 1 1 2 3 3 3 0 CpXC protein C1_1 PF00130.17 CCH60869.1 - 0.39 10.4 4.6 1.7 8.4 0.2 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_LEF5_C PF11792.3 CCH60869.1 - 0.5 9.7 6.3 0.13 11.7 0.5 2.7 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain HypA PF01155.14 CCH60869.1 - 0.6 9.8 9.0 2.2 8.0 2.6 2.9 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 CCH60869.1 - 1 8.9 6.4 14 5.2 0.0 3.8 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 OrfB_Zn_ribbon PF07282.6 CCH60869.1 - 1.4 8.6 8.1 12 5.6 0.2 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-CHY PF05495.7 CCH60869.1 - 1.4 9.1 8.7 0.9 9.7 0.2 2.7 2 1 0 3 3 3 0 CHY zinc finger SprT-like PF10263.4 CCH60869.1 - 2.1 7.9 4.9 30 4.2 0.1 2.2 1 1 1 2 2 2 0 SprT-like family IBR PF01485.16 CCH60869.1 - 2.6 7.9 11.3 12 5.8 1.1 2.9 1 1 1 2 2 2 0 IBR domain zf-C2HC5 PF06221.8 CCH60869.1 - 2.9 7.7 10.6 0.73 9.6 0.5 2.9 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-C4_Topoisom PF01396.14 CCH60869.1 - 3.6 7.1 13.3 0.11 12.0 2.1 3.2 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Nudix_N_2 PF14803.1 CCH60869.1 - 4.1 7.1 10.0 31 4.3 0.0 3.9 4 0 0 4 4 4 0 Nudix N-terminal zf-ISL3 PF14690.1 CCH60869.1 - 4.3 7.4 8.5 3.8 7.6 0.1 3.3 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rubredoxin PF00301.15 CCH60869.1 - 5.7 6.8 11.0 21 5.0 0.2 3.8 3 1 1 4 4 4 0 Rubredoxin RecR PF02132.10 CCH60869.1 - 7.4 6.0 8.9 55 3.3 2.7 3.2 2 1 0 2 2 2 0 RecR protein zf-AN1 PF01428.11 CCH60869.1 - 9 6.2 10.4 54 3.7 1.1 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger NOB1_Zn_bind PF08772.6 CCH60869.1 - 9.5 6.1 11.1 1.5 8.7 0.3 3.1 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PRCC PF10253.4 CCH60870.1 - 6.4e-06 26.9 2.2 7.3e-06 26.7 1.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF2771 PF10969.3 CCH60870.1 - 0.1 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) LicD PF04991.8 CCH60871.1 - 1.1e-46 159.5 4.1 1.1e-46 159.5 2.9 3.9 3 1 1 4 4 4 1 LicD family CobT PF06213.7 CCH60871.1 - 0.0013 17.8 22.4 0.0013 17.8 15.5 1.8 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT GAGA_bind PF06217.7 CCH60871.1 - 6.8 6.5 25.2 0.79 9.6 14.2 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family HLH PF00010.21 CCH60872.1 - 2.4e-12 46.3 4.0 7.7e-12 44.7 2.8 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CCH60873.1 - 4.6e-44 150.5 0.1 1.1e-43 149.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60873.1 - 8.2e-16 57.8 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCH60873.1 - 0.009 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCH60873.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF948 PF06103.6 CCH60873.1 - 2.5 8.0 9.4 8.6 6.2 6.5 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.8 CCH60873.1 - 2.9 8.3 7.2 5.3 7.5 3.6 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GFO_IDH_MocA PF01408.17 CCH60875.1 - 4.3e-09 36.9 0.0 6.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-HIT PF04438.11 CCH60876.1 - 4.5e-11 42.1 12.9 9.7e-11 41.1 8.9 1.6 1 0 0 1 1 1 1 HIT zinc finger Paramyxo_PCT PF14320.1 CCH60876.1 - 0.025 13.5 0.1 0.028 13.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered YL1_C PF08265.6 CCH60876.1 - 0.039 13.5 0.1 0.091 12.3 0.1 1.7 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain CDC14 PF08045.6 CCH60876.1 - 0.14 11.2 0.7 0.2 10.7 0.5 1.3 1 1 0 1 1 1 0 Cell division control protein 14, SIN component zf-MYND PF01753.13 CCH60876.1 - 0.17 11.7 12.2 0.34 10.8 8.5 1.5 1 0 0 1 1 1 0 MYND finger CPSF_A PF03178.10 CCH60877.1 - 6.7e-55 186.4 2.0 1.4e-54 185.3 0.2 2.5 2 1 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 CCH60877.1 - 3.2e-28 98.1 8.8 8.7e-28 96.7 6.1 1.7 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nop14 PF04147.7 CCH60877.1 - 0.024 12.5 6.5 0.043 11.7 4.5 1.3 1 0 0 1 1 1 0 Nop14-like family E7 PF00527.13 CCH60877.1 - 0.19 11.9 1.7 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 E7 protein, Early protein FAM176 PF14851.1 CCH60877.1 - 1.1 8.9 7.4 0.61 9.7 1.2 2.4 2 0 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.8 CCH60877.1 - 5.9 6.4 16.5 0.063 12.8 3.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Cut12 PF11500.3 CCH60877.1 - 7 6.3 12.9 11 5.6 6.1 2.8 3 0 0 3 3 3 0 Spindle pole body formation-associated protein AF1Q PF15017.1 CCH60877.1 - 7.6 6.5 20.5 11 6.0 8.3 4.0 4 0 0 4 4 4 0 Drug resistance and apoptosis regulator Sedlin_N PF04628.8 CCH60879.1 - 1.8e-12 47.2 0.7 2.2e-12 47.0 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.19 CCH60880.1 - 2e-72 244.3 0.0 2.3e-72 244.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCH60880.1 - 1.3e-06 27.6 0.0 0.00097 18.1 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCH60880.1 - 8e-06 26.0 0.0 0.00013 22.1 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCH60880.1 - 9.4e-06 25.5 0.1 3.2e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCH60880.1 - 1.4e-05 25.1 0.5 0.0043 16.9 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCH60880.1 - 0.00014 21.0 1.0 0.0079 15.3 0.0 2.7 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.14 CCH60880.1 - 0.0006 18.9 0.0 0.086 11.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CCH60880.1 - 0.012 14.5 0.1 0.34 9.7 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CCH60880.1 - 0.024 14.4 0.0 0.084 12.6 0.0 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 CCH60880.1 - 0.044 12.8 0.1 0.14 11.2 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Beta_elim_lyase PF01212.16 CCH60881.1 - 1.3e-73 247.6 0.0 1.7e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase YL1_C PF08265.6 CCH60882.1 - 8e-13 47.7 0.6 2.2e-12 46.3 0.4 1.8 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Turandot PF07240.6 CCH60882.1 - 0.12 11.8 0.2 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Cortex-I_coil PF09304.5 CCH60883.1 - 4.6 7.3 21.9 0.046 13.7 6.2 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil GDA1_CD39 PF01150.12 CCH60884.1 - 3.6e-119 398.1 0.0 5.5e-119 397.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NAD_kinase PF01513.16 CCH60885.1 - 5.6e-78 261.5 0.0 7.1e-78 261.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase 2C_adapt PF08793.5 CCH60885.1 - 0.11 12.4 0.6 0.32 10.9 0.4 1.8 1 0 0 1 1 1 0 2-cysteine adaptor domain Cupin_3 PF05899.7 CCH60885.1 - 0.11 11.8 0.0 17 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DAGK_cat PF00781.19 CCH60885.1 - 0.13 11.6 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Glyco_hydro_16 PF00722.16 CCH60886.1 - 1.7e-41 141.5 4.8 1.7e-41 141.5 3.3 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Apt1 PF10351.4 CCH60886.1 - 4 6.1 20.9 5.6 5.7 14.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cytochrom_C PF00034.16 CCH60887.1 - 5.1e-11 43.2 0.5 6.8e-11 42.8 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCH60887.1 - 5.5e-09 36.0 4.8 1e-07 32.0 3.3 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF3242 PF11586.3 CCH60887.1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Cytochrom_C550 PF14495.1 CCH60887.1 - 0.092 12.2 2.9 0.23 10.9 2.0 1.9 1 1 0 1 1 1 0 Cytochrome c-550 domain Haem_bd PF14376.1 CCH60887.1 - 0.14 11.8 0.2 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Haem-binding domain Cytochrom_C1 PF02167.10 CCH60887.1 - 0.15 11.7 0.8 0.29 10.7 0.3 1.9 1 1 1 2 2 2 0 Cytochrome C1 family HAD_2 PF13419.1 CCH60888.1 - 4.6e-25 88.8 0.0 5.9e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH60888.1 - 0.0075 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCH60888.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NifU_N PF01592.11 CCH60889.1 - 1.4e-51 173.6 0.0 1.6e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Flocculin_t3 PF13928.1 CCH60890.1 - 2.7e-13 49.7 17.6 2.7e-13 49.7 12.2 3.1 3 0 0 3 3 3 1 Flocculin type 3 repeat DUF4131 PF13567.1 CCH60890.1 - 1.3 8.4 10.9 2.3 7.5 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3328 PF11807.3 CCH60890.1 - 6.2 6.4 6.1 34 4.0 4.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) BTB_2 PF02214.17 CCH60891.1 - 1.3e-08 34.8 2.0 2.1e-05 24.6 0.1 3.0 2 1 0 2 2 2 2 BTB/POZ domain F-box-like PF12937.2 CCH60892.1 - 0.049 13.3 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 F-box-like RNase_T PF00929.19 CCH60893.1 - 8.4e-19 68.4 0.8 3.2e-18 66.5 0.1 2.1 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CCH60893.1 - 0.0024 17.3 1.0 0.011 15.2 0.1 2.5 2 1 0 2 2 2 1 3'-5' exonuclease AAA_5 PF07728.9 CCH60894.1 - 8.1e-128 420.8 1.7 2.4e-21 75.9 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCH60894.1 - 6.8e-34 116.3 0.0 2.4e-11 43.3 0.0 7.9 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CCH60894.1 - 1.1e-26 93.6 2.8 0.00044 20.4 0.0 8.2 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CCH60894.1 - 2.2e-23 82.8 0.7 0.00057 19.9 0.0 8.4 9 0 0 9 9 8 4 Sigma-54 interaction domain Sigma54_activat PF00158.21 CCH60894.1 - 3.4e-21 75.4 0.1 0.0011 18.5 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_17 PF13207.1 CCH60894.1 - 1.5e-20 74.2 22.6 0.0045 17.7 0.0 9.3 7 2 0 7 7 6 6 AAA domain AAA_14 PF13173.1 CCH60894.1 - 1.6e-19 70.0 1.1 0.00025 20.9 0.0 8.7 8 0 0 8 8 7 3 AAA domain AAA_22 PF13401.1 CCH60894.1 - 1.3e-18 67.3 0.4 0.062 13.4 0.0 8.2 7 0 0 7 7 7 4 AAA domain AAA_33 PF13671.1 CCH60894.1 - 6.9e-18 64.8 0.0 0.00043 20.1 0.0 7.2 7 0 0 7 7 6 3 AAA domain AAA_16 PF13191.1 CCH60894.1 - 1.1e-17 64.6 9.2 0.0043 17.0 0.0 8.0 8 1 0 8 8 7 4 AAA ATPase domain T2SE PF00437.15 CCH60894.1 - 4.3e-17 61.8 5.1 0.0036 16.2 0.2 6.3 6 0 0 6 6 6 5 Type II/IV secretion system protein AAA_19 PF13245.1 CCH60894.1 - 4e-15 55.3 5.2 0.036 13.7 0.1 6.5 6 0 0 6 6 6 4 Part of AAA domain AAA_30 PF13604.1 CCH60894.1 - 3.7e-14 52.7 0.0 0.099 12.2 0.0 7.9 7 1 0 7 7 7 2 AAA domain UPF0079 PF02367.12 CCH60894.1 - 4.1e-14 52.2 5.7 0.14 11.7 0.0 6.9 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CCH60894.1 - 8.6e-13 48.7 27.6 0.00049 20.4 0.1 8.5 7 1 1 8 8 6 4 ABC transporter RNA_helicase PF00910.17 CCH60894.1 - 8.1e-12 45.2 3.2 1.4 9.1 0.0 7.5 7 0 0 7 7 6 2 RNA helicase PduV-EutP PF10662.4 CCH60894.1 - 6.7e-11 41.8 1.9 0.032 13.7 0.0 6.3 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CCH60894.1 - 8.6e-11 42.3 3.2 0.34 11.4 0.0 6.7 6 0 0 6 6 5 2 Miro-like protein DUF258 PF03193.11 CCH60894.1 - 1.8e-10 40.2 5.7 0.36 9.9 0.4 6.3 6 0 0 6 6 6 3 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CCH60894.1 - 3.9e-10 39.4 0.9 0.47 9.8 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCH60894.1 - 6.5e-10 38.5 5.5 3.1 6.9 0.0 8.6 9 1 1 10 10 9 2 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CCH60894.1 - 2.9e-09 36.2 4.7 0.82 9.2 0.0 6.3 6 0 0 6 6 6 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CCH60894.1 - 1.3e-08 34.5 2.8 0.3 10.4 0.0 6.0 6 0 0 6 6 5 2 AAA domain AAA_28 PF13521.1 CCH60894.1 - 3.6e-08 33.5 9.8 1 9.2 0.1 6.8 6 0 0 6 6 6 2 AAA domain AAA_18 PF13238.1 CCH60894.1 - 5.2e-08 33.2 46.3 0.0074 16.5 0.0 10.8 8 2 0 8 8 6 4 AAA domain RuvB_N PF05496.7 CCH60894.1 - 2.7e-07 29.8 1.4 0.45 9.5 0.0 5.5 6 0 0 6 6 5 2 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 CCH60894.1 - 6.1e-07 29.0 4.3 0.85 9.0 0.1 6.1 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain NACHT PF05729.7 CCH60894.1 - 7.8e-07 28.8 11.8 0.2 11.2 0.0 6.6 7 0 0 7 7 6 1 NACHT domain AAA_7 PF12775.2 CCH60894.1 - 8.3e-07 28.3 6.8 0.64 9.0 0.0 5.7 7 0 0 7 7 6 3 P-loop containing dynein motor region D3 PhoH PF02562.11 CCH60894.1 - 9.1e-07 28.3 1.0 3.1 6.9 0.0 5.5 5 0 0 5 5 5 1 PhoH-like protein MobB PF03205.9 CCH60894.1 - 3.8e-06 26.6 8.1 0.53 9.9 0.1 6.7 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 CCH60894.1 - 1.1e-05 25.0 0.4 1.3 8.5 0.1 4.1 4 0 0 4 4 4 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_6 PF12774.2 CCH60894.1 - 0.00038 20.0 0.0 48 3.3 0.0 6.2 7 0 0 7 7 6 0 Hydrolytic ATP binding site of dynein motor region D1 Viral_helicase1 PF01443.13 CCH60894.1 - 0.00095 18.7 5.1 0.58 9.6 0.0 5.9 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 CCH60894.1 - 0.0021 18.4 1.8 0.026 14.8 0.1 12.7 7 2 1 8 8 5 2 AAA domain NTPase_1 PF03266.10 CCH60894.1 - 0.0076 15.9 13.0 4 7.1 0.2 5.5 6 0 0 6 6 5 0 NTPase Phe_ZIP PF08916.6 CCH60894.1 - 0.033 14.4 0.1 6 7.2 0.0 3.5 3 0 0 3 3 3 0 Phenylalanine zipper FtsK_SpoIIIE PF01580.13 CCH60894.1 - 2 7.8 9.6 4.5 6.6 0.0 4.9 6 0 0 6 6 6 0 FtsK/SpoIIIE family tRNA_int_endo PF01974.12 CCH60895.1 - 6e-25 86.8 0.1 1.1e-24 86.0 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF4140 PF13600.1 CCH60895.1 - 0.0037 17.6 1.6 0.0059 17.0 1.1 1.3 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 CCH60895.1 - 0.017 14.0 2.6 0.026 13.4 1.8 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 CCH60895.1 - 0.053 13.0 6.5 0.11 12.0 4.5 1.5 1 0 0 1 1 1 0 Septum formation initiator CDC45 PF02724.9 CCH60896.1 - 5e-212 705.3 1.8 5.7e-212 705.1 1.2 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 CCH60896.1 - 0.11 10.3 12.1 0.2 9.5 8.4 1.3 1 0 0 1 1 1 0 Nop14-like family Apc9 PF12856.2 CCH60897.1 - 2.7e-14 53.0 0.9 4.7e-14 52.2 0.2 1.7 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 9 adh_short PF00106.20 CCH60898.1 - 0.00017 21.5 0.0 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase PhoU_div PF01865.11 CCH60898.1 - 0.071 12.2 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF47 DUF1027 PF06265.6 CCH60898.1 - 0.083 12.7 3.1 0.22 11.3 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1027) WD40 PF00400.27 CCH60899.1 - 6e-16 57.6 19.8 2e-06 27.4 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 CCH60899.1 - 0.0017 18.2 2.0 0.0034 17.2 0.2 2.2 2 0 0 2 2 2 1 RWD domain zf-rbx1 PF12678.2 CCH60899.1 - 0.0062 16.6 7.9 0.015 15.3 5.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCH60899.1 - 0.011 15.5 9.2 0.024 14.4 6.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 CCH60899.1 - 0.18 11.6 9.6 0.42 10.4 6.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CCH60899.1 - 0.25 11.3 12.7 0.61 10.1 8.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EPSP_synthase PF00275.15 CCH60900.1 - 1.5e-138 461.8 0.0 2.2e-138 461.2 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCH60900.1 - 3.1e-100 334.4 0.0 5.2e-100 333.6 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CCH60900.1 - 5.4e-64 215.9 0.0 9.1e-64 215.1 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CCH60900.1 - 3.1e-38 131.1 0.0 3e-36 124.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CCH60900.1 - 2.3e-21 75.6 0.0 1.1e-20 73.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CCH60900.1 - 5.7e-16 58.8 0.0 4e-15 56.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CCH60900.1 - 8.6e-08 31.7 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CCH60900.1 - 4.4e-06 27.5 0.0 1.4e-05 25.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ThiF PF00899.16 CCH60900.1 - 0.014 15.1 0.0 0.08 12.7 0.0 2.3 2 0 0 2 2 2 0 ThiF family AAA_33 PF13671.1 CCH60900.1 - 0.016 15.0 0.0 0.082 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pyr_redox_3 PF13738.1 CCH60900.1 - 0.15 12.1 0.0 3.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-DHHC PF01529.15 CCH60901.1 - 5.5e-26 91.0 11.1 5.5e-26 91.0 7.7 2.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase Fungal_trans PF04082.13 CCH60902.1 - 3.9e-38 130.8 1.7 9.2e-38 129.5 1.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH60902.1 - 0.011 15.6 1.1 0.018 14.9 0.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2841 PF11001.3 CCH60903.1 - 4.2e-37 126.8 1.4 7.5e-37 125.9 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF2284 PF10050.4 CCH60903.1 - 0.0004 20.0 0.1 0.00076 19.1 0.1 1.4 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2284) Chordopox_A30L PF06015.7 CCH60903.1 - 0.0095 15.5 1.1 1.7 8.2 0.0 3.2 3 0 0 3 3 3 2 Chordopoxvirus A30L protein Cyclin PF08613.6 CCH60904.1 - 1.1e-38 133.0 10.1 8.5e-25 87.9 0.1 3.3 4 0 0 4 4 4 2 Cyclin CMV_1a PF12467.3 CCH60905.1 - 0.014 15.7 2.0 0.018 15.4 1.4 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Ribonuc_L-PSP PF01042.16 CCH60906.1 - 5.8e-39 132.5 0.7 7e-39 132.3 0.5 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Transp_cyt_pur PF02133.10 CCH60907.1 - 6.9e-88 295.1 37.0 8.3e-88 294.8 25.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin E1-E2_ATPase PF00122.15 CCH60908.1 - 6e-29 100.7 0.0 1.1e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCH60908.1 - 2.7e-14 54.1 0.0 6e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH60908.1 - 1.1e-10 42.0 0.1 2.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH60908.1 - 3e-07 30.3 0.0 9.8e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Nab2 PF11517.3 CCH60908.1 - 0.00092 19.2 0.3 1.3 9.1 0.1 2.6 2 0 0 2 2 2 2 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) EXS PF03124.9 CCH60909.1 - 1.2e-78 264.5 26.3 1.8e-78 263.9 18.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCH60909.1 - 2.5e-18 66.8 3.6 1.2e-17 64.6 2.5 2.0 1 1 0 1 1 1 1 SPX domain WD40 PF00400.27 CCH60910.1 - 1e-48 161.5 30.7 2.3e-10 39.9 1.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 CCH60910.1 - 3.4e-13 49.0 2.0 7.4e-13 47.9 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCH60910.1 - 2.5e-09 36.5 1.5 5.2e-09 35.5 1.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 CCH60910.1 - 6.6e-09 34.4 3.8 0.023 12.8 0.6 4.4 3 1 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCH60910.1 - 3.6e-05 22.7 0.5 0.23 10.1 0.0 4.0 1 1 2 4 4 4 1 Nup133 N terminal like PRANC PF09372.5 CCH60910.1 - 0.041 13.8 1.6 0.096 12.6 1.1 1.6 1 0 0 1 1 1 0 PRANC domain BBS2_Mid PF14783.1 CCH60910.1 - 0.061 13.1 0.0 2.3 8.0 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region zf-MYND PF01753.13 CCH60910.1 - 1.1 9.1 7.0 0.092 12.6 0.8 2.3 2 0 0 2 2 2 0 MYND finger CBM_21 PF03370.8 CCH60911.1 - 9.3e-15 54.5 0.0 1.5e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit Pyridox_oxidase PF01243.15 CCH60911.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Mito_carr PF00153.22 CCH60913.1 - 8.2e-49 163.2 6.5 2.9e-18 65.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ArfGap PF01412.13 CCH60914.1 - 2.6e-35 120.7 1.0 2.6e-35 120.7 0.7 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf NAD_binding_6 PF08030.7 CCH60914.1 - 0.013 15.4 3.3 0.025 14.4 2.3 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain BOP1NT PF08145.7 CCH60914.1 - 0.12 12.0 4.1 0.18 11.5 2.9 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain AA_kinase PF00696.23 CCH60915.1 - 1e-41 143.0 0.0 1.5e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CCH60915.1 - 1.5e-11 43.4 0.6 1.3e-06 27.7 0.1 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 CCH60915.1 - 1.7e-08 33.8 2.4 3.5e-06 26.4 0.4 2.7 2 0 0 2 2 2 2 ACT domain NAD_binding_1 PF00175.16 CCH60916.1 - 3.4e-28 98.3 0.0 5.1e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCH60916.1 - 8.6e-25 86.7 0.0 1.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CCH60916.1 - 0.00014 21.8 0.0 0.07 13.0 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CCH60916.1 - 0.00064 19.6 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain BAR_2 PF10455.4 CCH60917.1 - 3.3e-64 216.5 4.2 6.9e-64 215.5 2.9 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 CCH60917.1 - 2.6e-12 46.7 8.5 6.8e-12 45.3 4.7 2.2 1 1 1 2 2 2 1 BAR domain DUF4511 PF14974.1 CCH60917.1 - 0.017 14.8 1.5 0.038 13.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) HAND PF09110.6 CCH60917.1 - 1.6 9.1 6.7 0.8 10.1 2.2 2.2 2 0 0 2 2 2 0 HAND Ofd1_CTDD PF10637.4 CCH60918.1 - 3.7e-77 259.0 7.1 1.1e-72 244.4 4.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CCH60918.1 - 1.3e-13 51.3 0.1 4.6e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CCH60918.1 - 2.1e-05 24.7 0.0 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR_1 PF13232.1 CCH60919.1 - 3.8e-20 71.8 1.1 4.6e-20 71.5 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCH60919.1 - 5.5e-19 67.7 0.8 6.8e-19 67.4 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MIF4G PF02854.14 CCH60919.1 - 0.0066 15.8 0.2 0.0071 15.7 0.2 1.2 1 0 0 1 1 1 1 MIF4G domain Complex1_LYR_2 PF13233.1 CCH60919.1 - 0.017 15.5 0.6 0.021 15.3 0.4 1.1 1 0 0 1 1 1 0 Complex1_LYR-like Surf_Ag_VNR PF07244.10 CCH60919.1 - 0.073 13.4 1.4 0.088 13.2 0.5 1.4 2 0 0 2 2 2 0 Surface antigen variable number repeat Apq12 PF12716.2 CCH60920.1 - 0.0043 16.6 13.1 0.0043 16.6 9.1 2.1 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Peptidase_M50B PF13398.1 CCH60920.1 - 0.043 13.1 4.9 0.058 12.7 3.4 1.1 1 0 0 1 1 1 0 Peptidase M50B-like O-antigen_lig PF13425.1 CCH60920.1 - 0.052 13.5 4.3 0.061 13.3 3.0 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4383 PF14325.1 CCH60920.1 - 1.6 8.7 5.8 47 4.0 4.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) DnaJ-X PF14308.1 CCH60921.1 - 4.1e-59 199.2 9.2 4.1e-59 199.2 6.4 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCH60921.1 - 1.9e-25 88.3 1.3 1.9e-25 88.3 0.9 2.9 3 0 0 3 3 3 1 DnaJ domain Hydantoinase_A PF01968.13 CCH60921.1 - 0.094 11.7 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase TipAS PF07739.8 CCH60921.1 - 0.4 11.0 4.4 3 8.2 0.4 3.0 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Metallophos PF00149.23 CCH60922.1 - 1.1e-30 106.5 5.4 1.1e-30 106.5 3.8 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA PF00004.24 CCH60923.1 - 2.2e-39 134.6 0.0 4.5e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCH60923.1 - 1e-07 32.0 0.1 0.00034 20.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Vps4_C PF09336.5 CCH60923.1 - 1.7e-07 31.0 0.0 1.5e-06 27.9 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CCH60923.1 - 0.00012 22.2 0.2 0.0011 19.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCH60923.1 - 0.00012 21.2 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CCH60923.1 - 0.00062 18.5 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 CCH60923.1 - 0.00096 19.0 0.0 0.023 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCH60923.1 - 0.0019 17.6 0.6 0.45 9.8 0.1 2.7 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 CCH60923.1 - 0.0024 17.5 0.1 0.012 15.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Folliculin PF11704.3 CCH60923.1 - 0.0082 15.7 1.4 0.0082 15.7 1.0 2.6 3 0 0 3 3 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA_33 PF13671.1 CCH60923.1 - 0.0086 15.9 0.0 0.028 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH60923.1 - 0.012 15.3 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 CCH60923.1 - 0.017 14.2 2.1 0.02 14.0 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCH60923.1 - 0.019 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CCH60923.1 - 0.026 14.5 0.1 0.092 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CCH60923.1 - 0.08 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 CCH60923.1 - 1.2 9.4 5.7 0.84 9.9 0.0 3.3 3 1 0 3 3 2 0 AAA domain Not3 PF04065.10 CCH60924.1 - 1.3e-88 296.2 29.3 1.3e-88 296.2 20.3 2.6 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCH60924.1 - 5.4e-25 87.8 0.2 3.1e-24 85.3 0.1 2.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Septin PF00735.13 CCH60927.1 - 4.2e-106 354.0 0.4 5e-106 353.8 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCH60927.1 - 1e-08 35.1 0.1 1.7e-08 34.3 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCH60927.1 - 1.3e-07 30.9 0.1 2.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCH60927.1 - 4.2e-06 26.0 0.5 9e-06 24.9 0.3 1.7 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 CCH60927.1 - 1.3e-05 24.6 0.5 0.00019 20.8 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCH60927.1 - 1.9e-05 24.5 1.8 0.04 13.7 0.6 2.4 1 1 1 2 2 2 2 Dynamin family AAA_24 PF13479.1 CCH60927.1 - 0.00029 20.4 0.1 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CCH60927.1 - 0.00051 19.5 0.1 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 CCH60927.1 - 0.0012 19.3 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 CCH60927.1 - 0.0031 16.9 0.4 0.0056 16.1 0.2 1.4 1 1 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 CCH60927.1 - 0.0033 16.3 0.1 0.005 15.7 0.1 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 CCH60927.1 - 0.0052 16.6 0.1 0.016 15.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 CCH60927.1 - 0.0053 17.0 1.1 0.011 15.9 0.8 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 CCH60927.1 - 0.0058 16.7 0.1 0.033 14.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CCH60927.1 - 0.01 15.8 0.2 0.021 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.8 CCH60927.1 - 0.019 13.7 0.3 0.035 12.9 0.2 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.1 CCH60927.1 - 0.021 14.6 0.8 0.1 12.4 0.2 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CCH60927.1 - 0.029 14.0 0.1 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CCH60927.1 - 0.032 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CCH60927.1 - 0.06 12.2 0.1 0.097 11.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PduV-EutP PF10662.4 CCH60927.1 - 0.063 12.7 0.1 0.82 9.1 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CCH60927.1 - 0.086 11.7 0.1 0.14 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) FeoB_N PF02421.13 CCH60927.1 - 0.097 11.9 0.2 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 CCH60927.1 - 0.11 12.7 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Citrate_synt PF00285.16 CCH60928.1 - 5.1e-102 341.2 0.0 6.4e-102 340.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase BAR PF03114.13 CCH60929.1 - 8.7e-52 175.9 3.6 1e-51 175.6 2.5 1.0 1 0 0 1 1 1 1 BAR domain DUF4427 PF14468.1 CCH60929.1 - 0.017 14.8 0.2 0.28 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4427) MgtE_N PF03448.12 CCH60929.1 - 0.048 13.9 0.3 0.39 11.0 0.0 2.6 3 0 0 3 3 3 0 MgtE intracellular N domain V_ATPase_I PF01496.14 CCH60929.1 - 0.15 9.8 0.7 0.19 9.5 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4164 PF13747.1 CCH60929.1 - 0.37 10.9 2.3 1.4 9.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Grp1_Fun34_YaaH PF01184.14 CCH60930.1 - 6.2e-91 303.3 13.8 7.2e-91 303.1 9.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF997 PF06196.7 CCH60930.1 - 0.15 11.5 4.9 1.2 8.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF997) ABC2_membrane PF01061.19 CCH60931.1 - 3.5e-37 127.6 22.6 7.8e-37 126.4 15.7 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CCH60931.1 - 6.2e-30 104.2 0.0 1.4e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 CCH60931.1 - 1.1e-05 24.8 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCH60931.1 - 0.00041 19.5 0.1 0.00098 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCH60931.1 - 0.0017 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CCH60931.1 - 0.0079 15.7 0.3 0.027 13.9 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain EGF_2 PF07974.8 CCH60931.1 - 0.0099 16.0 6.8 0.0099 16.0 4.7 4.0 4 0 0 4 4 3 1 EGF-like domain AAA_28 PF13521.1 CCH60931.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CCH60931.1 - 0.058 13.3 0.0 0.21 11.4 0.0 2.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 CCH60931.1 - 0.083 12.5 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain hEGF PF12661.2 CCH60931.1 - 0.12 12.5 16.1 0.69 10.1 0.3 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF AAA_19 PF13245.1 CCH60931.1 - 0.32 10.7 0.3 0.66 9.7 0.2 1.4 1 0 0 1 1 1 0 Part of AAA domain PGK PF00162.14 CCH60932.1 - 4.7e-151 502.7 0.3 5.3e-151 502.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DNA_pol_B_thumb PF14791.1 CCH60933.1 - 2.6e-16 59.0 0.0 8.4e-16 57.4 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CCH60933.1 - 1e-15 57.7 0.1 1.7e-14 53.8 0.1 2.5 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 CCH60933.1 - 2e-13 50.2 0.2 1.8e-12 47.2 0.3 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 CCH60933.1 - 4.8e-07 29.2 0.0 1.3e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HAD PF12710.2 CCH60934.1 - 2.8e-13 50.4 0.1 3.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCH60934.1 - 4.5e-07 29.2 0.1 5.9e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 CCH60934.1 - 3.2e-06 26.6 0.0 4.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 CCH60934.1 - 0.0023 18.1 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase EF-hand_6 PF13405.1 CCH60935.1 - 0.021 14.7 2.4 3.7 7.6 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.1 CCH60935.1 - 0.054 13.1 1.3 6.3 6.4 0.1 2.8 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.1 CCH60935.1 - 0.095 12.8 8.3 0.078 13.1 2.7 2.7 1 1 1 2 2 2 0 EF-hand domain pair Flavodoxin_1 PF00258.20 CCH60935.1 - 0.14 12.1 0.5 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin EF-hand_1 PF00036.27 CCH60935.1 - 0.16 11.3 4.0 3.6 7.1 0.1 2.9 3 0 0 3 3 3 0 EF hand PLA2_B PF01735.13 CCH60936.1 - 1.8e-80 270.5 18.6 2.1e-35 121.8 2.2 3.2 3 0 0 3 3 3 3 Lysophospholipase catalytic domain Patatin PF01734.17 CCH60936.1 - 7e-05 22.8 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.22 CCH60937.1 - 1.7e-43 148.2 0.2 7.2e-22 78.1 0.0 4.5 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CCH60937.1 - 5.3e-17 62.6 0.5 6.2e-06 26.3 0.0 4.4 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 CCH60937.1 - 6e-14 51.7 0.1 2.9e-05 23.4 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH60937.1 - 3.4e-09 36.1 0.0 0.0029 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCH60937.1 - 8.5e-09 35.6 0.1 0.00026 21.1 0.0 3.7 4 1 0 4 4 2 2 AAA domain DUF258 PF03193.11 CCH60937.1 - 1.4e-08 34.0 0.1 0.00013 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCH60937.1 - 4.6e-08 33.9 0.0 0.004 17.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCH60937.1 - 9.7e-08 32.5 3.9 0.0017 18.7 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 CCH60937.1 - 4.2e-07 30.0 0.1 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CCH60937.1 - 7.3e-07 29.1 0.0 2.4e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 CCH60937.1 - 3.1e-06 27.4 0.5 0.31 11.2 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CCH60937.1 - 3.3e-06 27.0 0.0 0.0065 16.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase HEAT_2 PF13646.1 CCH60937.1 - 4.8e-06 26.7 1.7 0.00068 19.8 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats SbcCD_C PF13558.1 CCH60937.1 - 6.9e-06 25.8 0.1 0.047 13.5 0.0 3.7 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCH60937.1 - 7.2e-06 25.9 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCH60937.1 - 7.5e-06 25.5 0.1 0.27 10.6 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 CCH60937.1 - 8.7e-06 26.2 0.0 0.068 13.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 CCH60937.1 - 9e-06 24.9 0.0 0.25 10.3 0.0 3.6 3 1 1 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.17 CCH60937.1 - 2.4e-05 24.4 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CCH60937.1 - 4.7e-05 23.6 0.0 0.046 14.0 0.0 3.4 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 CCH60937.1 - 5.2e-05 22.1 0.1 0.25 10.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein CLASP_N PF12348.3 CCH60937.1 - 7.3e-05 22.2 0.9 0.14 11.4 0.0 2.6 2 1 0 3 3 2 2 CLASP N terminal MobB PF03205.9 CCH60937.1 - 7.7e-05 22.4 0.0 0.42 10.3 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MutS_V PF00488.16 CCH60937.1 - 0.00017 21.0 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 1 MutS domain V HEAT PF02985.17 CCH60937.1 - 0.0004 20.2 2.4 3.2 8.0 0.0 5.0 5 0 0 5 5 4 0 HEAT repeat Arch_ATPase PF01637.13 CCH60937.1 - 0.00063 19.5 0.2 0.61 9.7 0.0 3.0 3 0 0 3 3 2 1 Archaeal ATPase HEAT_EZ PF13513.1 CCH60937.1 - 0.00073 19.9 7.1 1.2 9.6 0.1 5.3 4 2 2 6 6 5 1 HEAT-like repeat AAA_13 PF13166.1 CCH60937.1 - 0.00076 18.0 2.5 1.3 7.3 0.0 3.7 4 1 0 4 4 3 1 AAA domain AAA_16 PF13191.1 CCH60937.1 - 0.0008 19.4 3.0 0.13 12.2 0.1 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 CCH60937.1 - 0.001 18.9 0.0 2.8 7.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain MMS19_C PF12460.3 CCH60937.1 - 0.0011 17.8 0.2 0.094 11.4 0.1 3.0 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal ParcG PF10274.4 CCH60937.1 - 0.0016 18.3 1.0 3.7 7.4 0.1 3.1 2 1 1 3 3 3 0 Parkin co-regulated protein PduV-EutP PF10662.4 CCH60937.1 - 0.0017 17.8 0.0 0.36 10.3 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 CCH60937.1 - 0.002 17.7 0.1 2.8 7.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain Vac14_Fab1_bd PF12755.2 CCH60937.1 - 0.002 18.4 0.3 0.26 11.6 0.0 3.3 3 1 2 5 5 2 1 Vacuolar 14 Fab1-binding region NACHT PF05729.7 CCH60937.1 - 0.0028 17.3 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 CCH60937.1 - 0.0098 15.3 0.1 6.3 6.2 0.0 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cnd1 PF12717.2 CCH60937.1 - 0.0099 15.7 0.1 0.62 9.8 0.0 3.4 4 1 0 4 4 2 1 non-SMC mitotic condensation complex subunit 1 AAA_25 PF13481.1 CCH60937.1 - 0.011 15.2 0.0 3.9 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain UME PF08064.8 CCH60937.1 - 0.014 15.3 0.6 0.071 13.0 0.2 2.2 1 1 1 2 2 2 0 UME (NUC010) domain T2SE PF00437.15 CCH60937.1 - 0.017 14.0 0.1 0.18 10.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 CCH60937.1 - 0.017 14.9 3.8 0.37 10.5 0.0 3.9 4 0 0 4 4 3 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CCH60937.1 - 0.039 13.4 0.0 3 7.2 0.0 3.2 3 1 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CCH60937.1 - 0.041 12.9 0.1 7.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 CCH60937.1 - 0.043 12.8 0.3 1.2 8.0 0.0 2.7 3 0 0 3 3 2 0 Septin NTPase_1 PF03266.10 CCH60937.1 - 0.053 13.2 0.2 9.4 5.9 0.0 2.6 2 0 0 2 2 2 0 NTPase Mg_chelatase PF01078.16 CCH60937.1 - 0.053 12.6 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 CCH60937.1 - 0.054 12.1 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 CCH60937.1 - 0.059 12.9 0.2 9 5.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adaptin_N PF01602.15 CCH60937.1 - 0.1 10.9 6.6 0.36 9.0 2.2 2.5 1 1 0 2 2 2 0 Adaptin N terminal region Pkinase PF00069.20 CCH60938.1 - 5.3e-60 202.7 0.0 1.1e-59 201.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60938.1 - 8.6e-26 90.5 0.0 6.1e-24 84.4 0.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH60938.1 - 4.6e-07 29.0 0.0 0.023 13.6 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCH60938.1 - 0.013 14.5 0.0 0.032 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Proteasome PF00227.21 CCH60939.1 - 3.7e-45 153.5 0.0 4.3e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Uteroglobin PF01099.12 CCH60939.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family OB_NTP_bind PF07717.11 CCH60940.1 - 1.7e-27 95.5 0.5 2e-26 92.0 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCH60940.1 - 1e-25 89.6 0.1 1e-25 89.6 0.1 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCH60940.1 - 1.2e-12 47.5 0.0 5.1e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH60940.1 - 1.5e-07 31.0 0.3 3.8e-07 29.7 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH60940.1 - 4.1e-06 26.9 0.1 1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCH60940.1 - 0.00019 20.4 0.4 0.0014 17.5 0.1 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.22 CCH60940.1 - 0.0014 18.8 6.8 0.03 14.6 0.5 3.3 2 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 CCH60940.1 - 0.0023 17.8 0.5 0.041 13.7 0.4 2.9 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CCH60940.1 - 0.0059 15.4 0.1 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 NB-ARC domain KaiC PF06745.8 CCH60940.1 - 0.0091 15.1 0.0 0.026 13.6 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.1 CCH60940.1 - 0.013 15.1 0.2 0.048 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CCH60940.1 - 0.014 14.8 0.3 0.043 13.2 0.1 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 CCH60940.1 - 0.073 13.1 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RNase_P_Rpp14 PF01900.14 CCH60940.1 - 0.073 12.9 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Rpp14/Pop5 family AAA_19 PF13245.1 CCH60940.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NAD_binding_8 PF13450.1 CCH60941.1 - 1.7e-11 43.9 0.0 3.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCH60941.1 - 4.5e-06 26.9 0.1 0.0058 17.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCH60941.1 - 0.00014 21.0 0.0 0.0092 15.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 CCH60941.1 - 0.00042 19.3 0.0 0.0018 17.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.10 CCH60941.1 - 0.0058 14.8 0.0 0.02 13.0 0.0 1.8 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 CCH60941.1 - 0.0095 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCH60941.1 - 0.011 15.5 0.0 0.045 13.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH60941.1 - 0.037 14.0 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCH60941.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding RRM_5 PF13893.1 CCH60942.1 - 1.5e-11 43.9 0.0 2.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH60942.1 - 2.9e-08 33.2 0.0 7.3e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60942.1 - 4.3e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCH60942.1 - 0.037 13.7 0.0 0.074 12.8 0.0 1.7 1 1 0 1 1 1 0 Limkain b1 Fcf2 PF08698.6 CCH60942.1 - 0.1 12.6 1.2 0.16 11.9 0.8 1.3 1 0 0 1 1 1 0 Fcf2 pre-rRNA processing AMP-binding PF00501.23 CCH60943.1 - 4.1e-62 209.9 0.0 5.9e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EB1 PF03271.12 CCH60944.1 - 3e-13 49.5 0.1 7.9e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CCH60944.1 - 6.7e-06 26.1 0.2 6.7e-06 26.1 0.1 2.0 3 0 0 3 3 3 1 Calponin homology (CH) domain FlxA PF14282.1 CCH60944.1 - 0.005 16.7 6.5 0.005 16.7 4.5 2.3 2 1 0 2 2 2 1 FlxA-like protein FlaC_arch PF05377.6 CCH60944.1 - 0.023 14.5 1.2 0.057 13.3 0.8 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CCH60944.1 - 0.074 12.5 1.5 0.15 11.6 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 CCH60944.1 - 0.18 11.3 0.7 0.31 10.5 0.5 1.3 1 0 0 1 1 1 0 IncA protein DUF4124 PF13511.1 CCH60944.1 - 1.1 9.3 3.6 0.78 9.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Peptidase_M41 PF01434.13 CCH60945.1 - 1.3e-73 246.9 0.0 2.2e-73 246.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCH60945.1 - 2.9e-43 147.2 0.1 9.2e-43 145.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCH60945.1 - 1.9e-10 40.9 3.4 5.2e-10 39.4 2.3 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CCH60945.1 - 9.9e-05 23.1 0.0 0.00038 21.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH60945.1 - 0.00024 21.2 0.1 0.028 14.5 0.1 3.1 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCH60945.1 - 0.00067 18.4 0.9 0.0013 17.5 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 CCH60945.1 - 0.00079 18.8 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 CCH60945.1 - 0.0016 17.5 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCH60945.1 - 0.0026 17.4 0.3 0.0026 17.4 0.2 2.4 3 0 0 3 3 2 1 Part of AAA domain AAA_5 PF07728.9 CCH60945.1 - 0.0035 17.0 0.1 0.016 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH60945.1 - 0.005 16.8 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 CCH60945.1 - 0.013 14.6 0.3 0.049 12.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 CCH60945.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCH60945.1 - 0.024 14.5 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CCH60945.1 - 0.028 14.3 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CCH60945.1 - 0.037 14.3 1.2 0.16 12.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 CCH60945.1 - 0.065 12.3 0.1 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CCH60945.1 - 0.23 10.8 2.0 0.38 10.1 0.3 2.0 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CCH60946.1 - 8.6e-121 401.2 0.0 1.2e-120 400.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCH60946.1 - 5.3e-20 71.9 0.1 9.2e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCH60946.1 - 5.7e-17 61.7 2.0 1.3e-16 60.5 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 CCH60946.1 - 0.024 14.5 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain MIS13 PF08202.6 CCH60947.1 - 8e-12 44.8 20.7 1.7e-09 37.1 12.5 3.0 3 1 0 3 3 3 2 Mis12-Mtw1 protein family DASH_Dad2 PF08654.5 CCH60947.1 - 0.26 11.2 7.3 1 9.3 0.4 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad2 Sedlin_N PF04628.8 CCH60948.1 - 4e-32 110.8 0.0 5.7e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCH60948.1 - 6.1e-06 25.9 0.1 9.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Sybindin-like family RVT_2 PF07727.9 CCH60949.1 - 1.7e-27 95.9 0.0 2.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PB1 PF00564.19 CCH60949.1 - 0.034 13.8 0.1 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 PB1 domain Cut8_C PF08559.5 CCH60951.1 - 1.9e-30 105.6 2.8 1.9e-30 105.6 2.0 2.2 2 1 0 2 2 2 1 Cut8 six-helix bundle Cut8_M PF14483.1 CCH60951.1 - 0.00066 19.4 0.2 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain FHIPEP PF00771.15 CCH60951.1 - 0.027 12.8 4.4 0.12 10.6 2.3 2.0 2 0 0 2 2 2 0 FHIPEP family Phostensin_N PF13916.1 CCH60951.1 - 1.4 8.9 6.5 2.8 8.0 4.5 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal WD40 PF00400.27 CCH60952.1 - 2e-11 43.3 13.0 4.7e-05 23.1 0.4 6.6 6 1 1 7 7 7 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCH60952.1 - 2.8e-05 23.5 0.0 0.42 10.1 0.0 4.1 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Lum_binding PF00677.12 CCH60953.1 - 2.3e-50 168.4 11.4 7e-27 93.1 1.3 2.2 2 0 0 2 2 2 2 Lumazine binding domain Asp PF00026.18 CCH60954.1 - 9.6e-47 159.7 4.5 1.2e-46 159.4 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH60954.1 - 6.2e-07 29.5 0.1 1.6e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal BAG PF02179.11 CCH60955.1 - 8e-14 51.5 5.4 1.1e-13 51.0 3.7 1.2 1 0 0 1 1 1 1 BAG domain tRNA-synt_1f PF01921.13 CCH60955.1 - 0.032 12.9 0.1 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) ARL2_Bind_BART PF11527.3 CCH60955.1 - 0.039 13.7 0.4 0.055 13.2 0.3 1.3 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART CDC37_N PF03234.9 CCH60955.1 - 0.039 14.2 1.0 0.046 14.0 0.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding GrpE PF01025.14 CCH60955.1 - 0.085 12.4 0.8 0.11 11.9 0.6 1.2 1 0 0 1 1 1 0 GrpE Apc5 PF12862.2 CCH60955.1 - 0.1 12.4 0.6 0.17 11.7 0.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 FAD_binding_1 PF00667.15 CCH60956.1 - 2.7e-64 216.6 0.0 5e-64 215.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CCH60956.1 - 1.8e-09 38.1 0.0 4.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCH60956.1 - 0.12 12.5 0.0 0.43 10.7 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SMC_N PF02463.14 CCH60957.1 - 1.9e-61 207.0 43.5 2.2e-39 134.9 3.6 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCH60957.1 - 1.9e-20 73.0 0.1 1.9e-20 73.0 0.1 2.7 4 0 0 4 4 4 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CCH60957.1 - 1.1e-07 32.3 43.9 1.1e-07 32.3 30.4 6.9 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.1 CCH60957.1 - 3.1e-05 23.4 0.0 7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH60957.1 - 0.12 12.3 83.8 1.3 8.9 17.6 6.4 2 2 1 3 3 3 0 AAA domain ABC_tran PF00005.22 CCH60957.1 - 0.46 10.7 0.0 0.46 10.7 0.0 6.7 4 2 2 6 6 6 0 ABC transporter Reo_sigmaC PF04582.7 CCH60957.1 - 1.7 7.7 36.4 0.31 10.1 1.2 5.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein Ribosomal_L29e PF01779.12 CCH60958.1 - 8e-25 86.4 8.1 1.2e-24 85.8 5.6 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Peptidase_C48 PF02902.14 CCH60959.1 - 3.5e-35 121.5 0.6 3.5e-35 121.5 0.4 2.8 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RINGv PF12906.2 CCH60960.1 - 8.4e-15 54.5 8.6 1.5e-14 53.7 6.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCH60960.1 - 0.078 12.8 7.2 0.15 11.9 5.0 1.5 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 CCH60960.1 - 0.12 12.3 5.4 0.35 10.8 3.7 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain MCPVI PF02993.9 CCH60960.1 - 3.5 7.7 3.1 9.8 6.2 2.1 1.7 1 0 0 1 1 1 0 Minor capsid protein VI APC_CDC26 PF10471.4 CCH60961.1 - 1.6e-07 31.9 13.9 5e-07 30.3 9.6 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Sulfatase_C PF14707.1 CCH60961.1 - 0.0078 16.5 0.8 0.0082 16.4 0.5 1.2 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase FlxA PF14282.1 CCH60961.1 - 0.0095 15.8 15.2 0.013 15.4 10.5 1.1 1 0 0 1 1 1 1 FlxA-like protein Luciferase_N PF05295.6 CCH60961.1 - 0.051 13.3 0.3 0.061 13.1 0.2 1.2 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain CENP-H PF05837.7 CCH60961.1 - 0.79 9.9 8.3 0.97 9.6 5.7 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4404 PF14357.1 CCH60961.1 - 1.2 9.5 9.1 1.7 9.1 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) IncA PF04156.9 CCH60961.1 - 2.5 7.6 9.8 3.3 7.2 6.8 1.1 1 0 0 1 1 1 0 IncA protein MMgT PF10270.4 CCH60962.1 - 4.2e-24 85.0 0.1 4.9e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter STAG PF08514.6 CCH60963.1 - 6.2e-05 22.6 2.7 6.2e-05 22.6 1.9 3.7 3 0 0 3 3 3 1 STAG domain HEAT PF02985.17 CCH60963.1 - 0.076 13.1 0.0 15 5.9 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Pox_H7 PF04787.7 CCH60964.1 - 0.017 14.8 0.3 0.032 14.0 0.2 1.5 1 0 0 1 1 1 0 Late protein H7 Zip PF02535.17 CCH60965.1 - 4.3e-56 190.2 16.2 7.1e-48 163.2 6.7 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter MFMR PF07777.6 CCH60965.1 - 0.2 11.5 15.1 0.3 11.0 10.5 1.2 1 0 0 1 1 1 0 G-box binding protein MFMR NST1 PF13945.1 CCH60965.1 - 1.9 8.5 10.9 5.9 6.9 7.7 1.6 2 0 0 2 2 2 0 Salt tolerance down-regulator SWIRM PF04433.12 CCH60966.1 - 2.2e-33 114.2 0.1 7.9e-33 112.4 0.1 2.0 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 CCH60966.1 - 3.3e-12 45.7 2.5 5.1e-12 45.1 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCH60966.1 - 2.5e-07 30.6 0.0 4.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH60966.1 - 3.5e-07 30.2 0.1 2.3e-06 27.6 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Elf1 PF05129.8 CCH60966.1 - 0.011 15.3 0.5 0.034 13.8 0.3 1.8 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1825 PF08855.5 CCH60966.1 - 0.16 11.9 5.2 0.48 10.4 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) SNF2_N PF00176.18 CCH60967.1 - 4.8e-65 219.2 0.6 4.8e-65 219.2 0.4 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH60967.1 - 1e-15 57.3 0.0 3.4e-14 52.4 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH60967.1 - 0.00012 21.5 0.0 0.00067 19.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Erg28 PF03694.8 CCH60968.1 - 1.8e-42 143.8 3.6 2.2e-42 143.5 2.5 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF308 PF03729.8 CCH60968.1 - 0.038 13.9 1.2 0.13 12.2 0.3 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Zein PF01559.11 CCH60968.1 - 0.096 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Zein seed storage protein F_actin_cap_B PF01115.12 CCH60969.1 - 1.7e-91 305.7 2.8 2e-91 305.5 2.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit bZIP_1 PF00170.16 CCH60971.1 - 1.5e-13 50.5 5.1 3.2e-13 49.4 3.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCH60971.1 - 9.2e-06 25.3 6.8 2.4e-05 24.0 4.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DUF4653 PF15546.1 CCH60971.1 - 0.017 14.3 0.6 0.026 13.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) bZIP_Maf PF03131.12 CCH60971.1 - 0.088 13.1 8.7 0.038 14.2 3.9 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor eRF1_2 PF03464.10 CCH60972.1 - 5.2e-28 98.0 0.1 9.2e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCH60972.1 - 7.7e-25 87.3 1.9 1.7e-24 86.2 0.0 2.5 3 1 0 3 3 3 1 eRF1 domain 3 eRF1_1 PF03463.10 CCH60972.1 - 2.4e-10 40.0 0.1 3.9e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Rer1 PF03248.8 CCH60973.1 - 1.9e-71 239.2 10.7 2.2e-71 239.0 7.4 1.0 1 0 0 1 1 1 1 Rer1 family PHZA_PHZB PF03284.8 CCH60973.1 - 0.041 12.9 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B DUF846 PF05832.7 CCH60973.1 - 1.6 8.4 10.5 3.3 7.4 7.3 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) PQ-loop PF04193.9 CCH60974.1 - 5.6e-06 25.8 5.7 5.6e-06 25.8 4.0 4.3 4 1 1 5 5 5 2 PQ loop repeat DUF2975 PF11188.3 CCH60974.1 - 0.47 10.1 13.9 1.5 8.5 3.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) PLDc_2 PF13091.1 CCH60975.1 - 3.2e-15 55.9 0.3 7.9e-07 28.8 0.0 2.8 2 1 1 3 3 3 2 PLD-like domain PLDc PF00614.17 CCH60975.1 - 9.8e-10 37.9 0.4 0.0014 18.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif cNMP_binding PF00027.24 CCH60976.1 - 6.5e-44 147.6 0.0 2.5e-23 81.7 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CCH60976.1 - 2.5e-07 30.0 1.6 9.2e-07 28.1 1.1 2.0 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ALS_ss_C PF10369.4 CCH60978.1 - 1.3e-19 69.6 0.2 6.8e-19 67.3 0.0 2.3 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 CCH60978.1 - 1.1e-11 43.8 0.1 2.6e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 CCH60978.1 - 6.3e-08 32.3 0.1 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.1 CCH60978.1 - 0.0091 16.3 0.3 0.077 13.3 0.0 2.2 2 0 0 2 2 2 1 ACT domain Ribosomal_L27 PF01016.14 CCH60979.1 - 2.8e-31 107.1 3.1 7.2e-31 105.8 0.2 2.3 2 0 0 2 2 2 1 Ribosomal L27 protein DUF2924 PF11149.3 CCH60979.1 - 3 7.8 12.3 0.31 11.0 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2924) Cyclin_C PF02984.14 CCH60979.1 - 3.9 7.4 8.1 3 7.8 0.7 2.6 1 1 0 2 2 2 0 Cyclin, C-terminal domain DUF1325 PF07039.6 CCH60980.1 - 1.6e-34 118.3 0.0 4.8e-34 116.7 0.0 1.9 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 CCH60980.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) NIT PF08376.5 CCH60980.1 - 0.086 12.3 0.8 0.13 11.7 0.6 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing PilZ PF07238.9 CCH60980.1 - 0.12 12.4 0.0 0.47 10.4 0.0 2.1 1 1 0 1 1 1 0 PilZ domain Agenet PF05641.7 CCH60980.1 - 0.33 11.1 6.6 9.4 6.4 0.1 3.7 4 0 0 4 4 4 0 Agenet domain Mito_fiss_reg PF05308.6 CCH60980.1 - 3.3 6.9 35.4 0.94 8.7 7.9 3.3 2 1 1 3 3 3 0 Mitochondrial fission regulator RRM_1 PF00076.17 CCH60981.1 - 5.6e-57 189.2 0.0 8.2e-18 63.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60981.1 - 3.4e-37 126.2 0.0 2.4e-11 43.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60981.1 - 1.5e-22 79.2 0.0 4.6e-07 29.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2015 PF09435.5 CCH60982.1 - 8.2e-40 135.5 0.2 8.9e-40 135.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) WD40 PF00400.27 CCH60983.1 - 3.2e-49 163.1 16.1 2.2e-10 39.9 0.5 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CCH60983.1 - 8.2e-12 44.0 8.7 0.0086 14.2 0.0 5.0 2 1 1 4 4 4 4 Nucleoporin Nup120/160 Nbas_N PF15492.1 CCH60983.1 - 3e-07 29.8 0.9 0.17 10.9 0.0 4.2 3 2 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 CCH60983.1 - 8e-07 28.1 4.4 0.12 11.0 0.0 4.6 1 1 2 4 4 4 2 Nup133 N terminal like Hira PF07569.6 CCH60983.1 - 1.3e-05 24.5 0.0 0.1 11.8 0.0 4.2 3 1 1 4 4 4 1 TUP1-like enhancer of split DUF3312 PF11768.3 CCH60983.1 - 0.0019 16.5 0.0 0.0052 15.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 CCH60983.1 - 0.012 13.9 0.0 0.47 8.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Choline_sulf_C PF12411.3 CCH60983.1 - 0.095 12.5 0.5 10 6.0 0.2 2.9 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal DUF2373 PF10180.4 CCH60984.1 - 1.9e-22 78.5 2.7 3.8e-22 77.5 1.9 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DDHD PF02862.12 CCH60984.1 - 0.13 12.0 10.7 0.24 11.1 1.1 2.2 2 0 0 2 2 2 0 DDHD domain DUF4195 PF13836.1 CCH60985.1 - 0.0057 16.3 0.2 0.0084 15.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4195) Arrestin_N PF00339.24 CCH60986.1 - 3.3e-13 49.7 0.3 3e-10 40.0 0.2 2.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCH60986.1 - 0.0023 17.4 0.2 0.008 15.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like WD40 PF00400.27 CCH60987.1 - 2.5e-07 30.2 0.0 0.0047 16.7 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat DSPn PF14671.1 CCH60988.1 - 3.4e-51 172.9 0.9 6.7e-51 171.9 0.1 2.0 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCH60988.1 - 2.1e-25 88.8 0.4 5.3e-24 84.2 0.0 2.7 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CCH60988.1 - 0.00041 20.4 2.3 0.0016 18.5 0.0 2.8 3 1 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CCH60988.1 - 0.0005 19.4 0.0 0.0005 19.4 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CCH60988.1 - 0.0016 17.8 0.5 0.0031 16.9 0.1 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CCH60988.1 - 0.093 12.9 0.0 0.093 12.9 0.0 2.5 3 0 0 3 3 3 0 Tyrosine phosphatase family RRM_1 PF00076.17 CCH60989.1 - 2.7e-38 129.4 3.9 4e-13 48.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH60989.1 - 5.2e-21 74.4 0.1 3.3e-05 23.7 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH60989.1 - 2.7e-15 55.9 4.5 3.3e-06 26.8 0.5 4.8 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCH60989.1 - 0.00018 21.2 3.0 1.6 8.6 0.1 4.1 3 1 0 3 3 3 3 RNA binding motif Nup35_RRM_2 PF14605.1 CCH60989.1 - 0.0049 16.6 0.2 0.32 10.7 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF500 PF04366.7 CCH60990.1 - 1.9e-43 146.8 0.1 4.8e-43 145.6 0.1 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCH60990.1 - 1.4e-16 59.6 0.1 3e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH60990.1 - 5.1e-14 51.5 0.1 1.1e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH60990.1 - 8.8e-13 47.5 0.1 2e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain ProRS-C_1 PF09180.6 CCH60991.1 - 3e-26 91.1 1.0 1.2e-25 89.2 0.8 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CCH60991.1 - 1.3e-22 80.1 0.1 2.3e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH60991.1 - 2.5e-19 68.9 0.1 6.7e-19 67.6 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CCH60991.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.7 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain DUF2427 PF10348.4 CCH60992.1 - 2 8.0 5.7 7.8 6.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) SUR7 PF06687.7 CCH60993.1 - 2.7e-11 43.4 23.9 2.7e-11 43.4 16.6 2.0 2 0 0 2 2 2 1 SUR7/PalI family PAT1 PF09770.4 CCH60993.1 - 0.99 7.5 30.2 1.3 7.1 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WHIM1 PF15612.1 CCH60994.1 - 0.021 14.7 0.0 0.098 12.6 0.0 2.2 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Pkinase PF00069.20 CCH60995.1 - 2.2e-70 236.8 0.0 3.1e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH60995.1 - 3.7e-39 134.3 0.0 5.2e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCH60995.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1978 PF09321.5 CCH60995.1 - 0.016 14.6 0.9 0.03 13.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Kinase-like PF14531.1 CCH60995.1 - 0.024 13.6 0.0 0.11 11.4 0.0 2.0 2 1 0 2 2 2 0 Kinase-like ABC1 PF03109.11 CCH60995.1 - 0.064 13.2 0.1 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 ABC1 family APH PF01636.18 CCH60995.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glycogen_syn PF05693.8 CCH60996.1 - 0 1091.2 0.0 0 1091.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CCH60996.1 - 1.4e-10 40.8 0.0 5.1e-07 29.2 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCH60996.1 - 2.5e-06 27.7 0.2 5.3e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 CCH60996.1 - 6e-05 22.6 0.1 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain SLT_L PF14718.1 CCH60997.1 - 0.045 13.5 0.1 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain FLO_LFY PF01698.11 CCH60997.1 - 3.1 6.5 8.8 6.4 5.5 6.1 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein PAP2 PF01569.16 CCH61000.1 - 2.9e-11 43.1 7.7 2.9e-11 43.1 5.4 2.6 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCH61000.1 - 0.0018 17.8 8.6 0.0018 17.8 6.0 2.2 2 1 0 2 2 2 1 PAP2 superfamily RNB PF00773.14 CCH61001.1 - 9.4e-95 317.6 0.3 2.7e-94 316.1 0.0 1.8 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 CCH61001.1 - 8.2e-13 48.6 2.4 2.2e-12 47.2 1.7 1.7 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CCH61001.1 - 0.018 14.5 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain Acetyltransf_13 PF13880.1 CCH61002.1 - 5.5e-16 58.0 0.3 4.2e-15 55.2 0.0 2.4 2 1 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CCH61002.1 - 6.1e-07 28.8 0.1 1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.1 CCH61002.1 - 0.0041 17.2 0.0 0.0091 16.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCH61002.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 CCH61002.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3164 PF11363.3 CCH61002.1 - 0.082 12.2 0.1 0.22 10.8 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3164) Glyco_hydro_65m PF03632.10 CCH61003.1 - 3.5e-93 312.2 0.8 1.5e-92 310.1 0.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CCH61003.1 - 1.5e-32 112.9 1.6 2.9e-32 111.9 1.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF2951 PF11166.3 CCH61004.1 - 4 7.3 7.3 0.84 9.5 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) UPF0086 PF01868.11 CCH61005.1 - 3.7e-14 52.1 0.0 9.1e-14 50.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function UPF0086 CTP-dep_RFKase PF01982.11 CCH61005.1 - 0.026 14.1 0.5 0.063 12.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF120 SMC_N PF02463.14 CCH61005.1 - 0.054 12.7 0.8 0.095 11.9 0.6 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain COMPASS-Shg1 PF05205.7 CCH61006.1 - 1.1e-19 70.6 8.3 1.4e-19 70.3 5.7 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 RhoGAP PF00620.22 CCH61007.1 - 1.3e-40 138.5 2.4 9e-40 135.7 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CCH61007.1 - 1.4e-10 41.2 2.1 1.4e-10 41.2 1.5 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3015 PF11220.3 CCH61007.1 - 0.26 10.8 3.5 0.18 11.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) UBX PF00789.15 CCH61008.1 - 2.2e-07 30.8 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain Vps26 PF03643.10 CCH61009.1 - 1.3e-102 342.2 0.7 1.5e-102 342.0 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Imm11 PF15563.1 CCH61009.1 - 0.001 18.2 0.1 0.0015 17.7 0.1 1.2 1 0 0 1 1 1 1 Immunity protein 11 Arrestin_N PF00339.24 CCH61009.1 - 0.0023 17.7 0.6 0.014 15.2 0.1 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 CCH61009.1 - 0.032 13.3 0.1 0.068 12.2 0.0 1.5 2 0 0 2 2 2 0 Rgp1 Gypsy PF07253.6 CCH61010.1 - 0.12 10.6 0.1 0.21 9.8 0.0 1.3 1 0 0 1 1 1 0 Gypsy protein Tim54 PF11711.3 CCH61011.1 - 3.5e-118 394.5 0.1 3.1e-116 388.1 0.1 2.0 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Lysine_decarbox PF03641.9 CCH61012.1 - 4.1e-44 149.6 0.0 5.9e-44 149.1 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase FlbD PF06289.6 CCH61012.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein (FlbD) Methyltransf_16 PF10294.4 CCH61013.1 - 8.2e-23 80.7 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CCH61013.1 - 0.00034 20.2 0.0 0.00081 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH61013.1 - 0.00077 19.2 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH61013.1 - 0.0031 16.9 0.0 0.0061 15.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCH61013.1 - 0.0035 17.9 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH61013.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CCH61013.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 CCH61014.1 - 3e-33 115.0 0.1 4.3e-32 111.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61014.1 - 1.6e-18 66.7 0.0 4.9e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PhnA_Zn_Ribbon PF08274.7 CCH61014.1 - 0.094 12.5 0.3 0.23 11.2 0.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DNA_ligase_ZBD PF03119.11 CCH61014.1 - 0.12 12.1 0.1 0.29 10.8 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain HbrB PF08539.6 CCH61015.1 - 2.5e-34 118.4 3.5 4.9e-34 117.4 2.4 1.5 1 0 0 1 1 1 1 HbrB-like DUF2457 PF10446.4 CCH61015.1 - 0.0036 16.1 15.0 0.0071 15.1 10.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CLN3 PF02487.12 CCH61016.1 - 1.8e-102 343.1 27.5 4.5e-100 335.2 19.1 2.0 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.11 CCH61016.1 - 0.00043 19.1 18.1 0.00043 19.1 12.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1674 PF07896.7 CCH61017.1 - 9.8e-18 64.1 5.9 2.2e-17 62.9 4.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) adh_short PF00106.20 CCH61018.1 - 1.3e-16 60.9 0.0 4.6e-15 55.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH61018.1 - 4.4e-09 36.2 0.0 9.2e-09 35.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Esterase PF00756.15 CCH61019.1 - 1.8e-24 86.5 0.1 2.2e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCH61019.1 - 0.025 14.3 0.0 0.039 13.6 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CCH61019.1 - 0.14 11.7 1.1 0.21 11.1 0.7 1.3 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 CCH61019.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.15 CCH61020.1 - 2e-34 119.1 0.0 2.4e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCH61020.1 - 4.8e-05 23.1 0.0 8.4e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCH61020.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.8 CCH61020.1 - 0.13 11.8 2.3 0.45 10.0 1.5 1.9 1 1 0 1 1 1 0 PGAP1-like protein Esterase PF00756.15 CCH61021.1 - 3.3e-32 111.9 0.0 4.1e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCH61021.1 - 8.4e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCH61021.1 - 0.0064 16.1 0.1 0.013 15.0 0.1 1.5 1 1 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 CCH61021.1 - 0.048 12.8 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF915 PF06028.6 CCH61021.1 - 0.1 11.6 0.1 0.95 8.4 0.1 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CCH61021.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.27 CCH61022.1 - 7e-15 54.2 0.0 4.9e-05 23.0 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PD40 PF07676.7 CCH61022.1 - 0.031 13.9 0.1 11 5.7 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 CCH61022.1 - 0.076 12.5 0.0 1.5 8.4 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Sld5 PF05916.6 CCH61023.1 - 2.9e-15 56.4 1.2 4.6e-15 55.8 0.8 1.3 1 0 0 1 1 1 1 GINS complex protein Mem_trans PF03547.13 CCH61025.1 - 2.7e-64 216.8 15.8 4.1e-64 216.2 10.9 1.3 1 0 0 1 1 1 1 Membrane transport protein MAP65_ASE1 PF03999.7 CCH61025.1 - 0.083 11.4 10.5 0.11 11.0 7.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Cytokin_check_N PF10407.4 CCH61026.1 - 5.2e-28 96.4 4.4 1.5e-27 95.0 3.0 1.9 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 CCH61027.1 - 1.8e-17 64.0 5.5 1.8e-17 64.0 3.8 2.0 1 1 1 2 2 2 1 Cysteine-rich secretory protein family DUF3568 PF12092.3 CCH61027.1 - 0.0021 17.7 3.0 0.0041 16.8 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3568) DCAF15_WD40 PF14939.1 CCH61027.1 - 0.04 13.2 0.4 0.061 12.6 0.3 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat KH_1 PF00013.24 CCH61028.1 - 2.3e-54 180.8 49.8 4.9e-10 38.8 1.4 10.2 9 1 0 9 9 9 8 KH domain KH_3 PF13014.1 CCH61028.1 - 5.2e-28 96.1 45.9 9.5e-06 25.1 3.1 10.0 10 0 0 10 10 10 7 KH domain KH_4 PF13083.1 CCH61028.1 - 0.16 11.6 9.3 0.39 10.3 0.2 4.3 4 0 0 4 4 4 0 KH domain SLS PF14611.1 CCH61028.1 - 0.32 10.4 31.4 0.0072 15.7 2.0 5.1 4 2 2 6 6 6 0 Mitochondrial inner-membrane-bound regulator Actin PF00022.14 CCH61029.1 - 1.6e-93 313.2 0.1 1.3e-55 188.4 0.1 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCH61029.1 - 8.5e-05 21.3 0.0 0.012 14.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein Mem_trans PF03547.13 CCH61029.1 - 0.27 9.4 0.2 0.35 9.1 0.2 1.3 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.12 CCH61029.1 - 7.4 6.2 16.7 0.75 9.5 6.7 2.1 2 0 0 2 2 2 0 DDHD domain DUF3808 PF10300.4 CCH61030.1 - 3.9e-144 480.7 3.8 4.8e-144 480.4 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 CCH61030.1 - 0.053 13.1 4.8 0.62 9.7 0.1 3.5 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 CCH61030.1 - 0.23 11.4 3.3 5.6 7.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_4 PF12763.2 CCH61031.1 - 0.00082 19.0 0.6 0.0054 16.4 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Vps51 PF08700.6 CCH61032.1 - 1.1e-06 28.3 0.2 1.1e-06 28.3 0.2 1.9 2 0 0 2 2 2 1 Vps51/Vps67 RNA_pol_Rpb1_5 PF04998.12 CCH61032.1 - 0.012 14.8 3.0 0.016 14.4 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Arrestin_C PF02752.17 CCH61033.1 - 3.2e-15 56.4 0.4 3.2e-15 56.4 0.3 5.2 5 2 0 5 5 5 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCH61033.1 - 1.6e-08 34.4 0.1 1.4e-05 24.9 0.0 2.9 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Zip PF02535.17 CCH61033.1 - 0.031 13.2 8.0 0.12 11.3 5.5 2.0 1 0 0 1 1 1 0 ZIP Zinc transporter OTCace PF00185.19 CCH61034.1 - 7e-44 149.4 0.1 1.2e-43 148.7 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CCH61034.1 - 2.1e-41 140.9 0.1 3.2e-41 140.3 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Zn_clus PF00172.13 CCH61035.1 - 2.2e-11 43.4 10.6 3.5e-11 42.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LT-IIB PF06453.6 CCH61035.1 - 0.04 13.5 0.6 0.11 12.1 0.4 1.7 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) BRCT PF00533.21 CCH61036.1 - 8.8e-10 38.6 16.9 0.0017 18.4 0.5 5.2 4 2 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCH61036.1 - 0.0006 19.6 0.1 0.18 11.6 0.0 3.5 3 0 0 3 3 3 1 twin BRCT domain UvrD_C PF13361.1 CCH61037.1 - 3.2e-71 240.6 0.1 3.2e-71 240.6 0.1 3.5 4 1 1 5 5 5 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCH61037.1 - 3e-64 217.3 0.3 3e-64 217.3 0.2 3.1 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CCH61037.1 - 7.9e-11 41.5 0.1 1.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 CCH61037.1 - 1.6e-08 34.6 0.0 2.2e-05 24.5 0.0 3.1 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 CCH61037.1 - 0.00065 19.3 0.0 0.0017 18.0 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 CCH61037.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ribosomal_L21p PF00829.16 CCH61038.1 - 0.05 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein SAPS PF04499.10 CCH61039.1 - 2.4e-145 484.8 16.2 2.4e-145 484.8 11.2 3.7 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein IF-2B PF01008.12 CCH61040.1 - 9.5e-75 251.1 0.0 1.1e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 CCH61040.1 - 0.067 12.8 0.1 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sin_N PF04801.8 CCH61041.1 - 1.8e-14 53.4 1.7 2.9e-14 52.7 1.2 1.3 1 0 0 1 1 1 1 Sin-like protein conserved region DEAD PF00270.24 CCH61042.1 - 6.5e-39 133.1 0.0 1.4e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61042.1 - 4.7e-21 74.4 0.0 1.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCH61042.1 - 2.5e-17 62.1 0.1 5.5e-17 61.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCH61042.1 - 5.7e-05 23.0 6.4 0.00085 19.1 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pam16 PF03656.8 CCH61043.1 - 3.9e-46 155.9 4.2 4.5e-46 155.7 2.9 1.1 1 0 0 1 1 1 1 Pam16 NTP_transferase PF00483.18 CCH61043.1 - 0.0085 15.4 0.2 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase PrgU PF09627.5 CCH61043.1 - 0.036 13.6 2.7 0.037 13.6 0.7 1.7 1 1 0 2 2 2 0 PrgU-like protein PHD PF00628.24 CCH61044.1 - 4.5e-09 35.8 7.6 9e-09 34.8 5.2 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CCH61044.1 - 4.2e-08 33.6 2.5 1.9e-07 31.4 0.0 3.0 2 1 0 2 2 2 1 SET domain GATA PF00320.22 CCH61045.1 - 3.9e-16 58.0 2.8 1.1e-15 56.6 2.0 1.9 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCH61045.1 - 0.033 13.5 0.6 0.066 12.5 0.4 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Cpn60_TCP1 PF00118.19 CCH61046.1 - 3.1e-145 484.5 6.5 3.5e-145 484.3 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_U59 PF04529.7 CCH61046.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus U59 protein ADH_zinc_N PF00107.21 CCH61047.1 - 3.1e-13 49.3 0.1 8.8e-13 47.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH61047.1 - 2.8e-05 23.8 0.4 0.00025 20.7 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 CCH61047.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 CCH61048.1 - 6.7e-26 89.1 10.6 1e-06 28.3 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat SUN PF03856.8 CCH61049.1 - 4.4e-80 268.5 8.2 6.4e-80 268.0 5.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SPATIAL PF15256.1 CCH61049.1 - 0.032 14.3 1.1 0.17 11.9 1.2 1.8 2 0 0 2 2 2 0 SPATIAL RAP1 PF07218.6 CCH61049.1 - 0.62 8.0 16.2 0.88 7.5 11.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DHHW PF14286.1 CCH61049.1 - 4.5 6.4 8.7 7.6 5.7 6.0 1.3 1 0 0 1 1 1 0 DHHW protein Lectin_leg-like PF03388.8 CCH61050.1 - 3.2e-08 32.9 0.1 2.8e-07 29.8 0.2 2.0 2 0 0 2 2 2 1 Legume-like lectin family Lectin_legB PF00139.14 CCH61050.1 - 7.1e-06 25.5 0.9 7.1e-06 25.5 0.6 2.1 2 1 0 2 2 2 1 Legume lectin domain Alb1 PF09135.6 CCH61052.1 - 9.5e-09 35.8 12.9 9.5e-09 35.8 8.9 1.6 1 1 0 1 1 1 1 Alb1 BORG_CEP PF14957.1 CCH61052.1 - 0.88 10.4 3.3 0.59 11.0 0.7 1.8 1 1 1 2 2 2 0 Cdc42 effector Nucleo_P87 PF07267.6 CCH61052.1 - 2.4 6.7 7.5 2.6 6.6 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 eIF-3c_N PF05470.7 CCH61052.1 - 2.4 6.1 8.1 2.8 5.9 5.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2413 PF10310.4 CCH61053.1 - 8.2e-105 351.1 38.5 1e-104 350.8 26.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF2868 PF11067.3 CCH61053.1 - 0.14 11.3 1.7 0.31 10.1 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) ALMS_motif PF15309.1 CCH61053.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.7 4 0 0 4 4 4 0 ALMS motif LSM PF01423.17 CCH61054.1 - 1.8e-14 53.0 0.2 3.1e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 LSM domain PUF PF00806.14 CCH61054.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat GCD14 PF08704.5 CCH61055.1 - 3.9e-80 268.9 5.7 1.5e-77 260.4 4.0 3.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 CCH61055.1 - 5.8e-06 26.8 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCH61055.1 - 1.7e-05 23.9 0.0 3.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCH61055.1 - 2.2e-05 24.4 0.0 3.6e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH61055.1 - 9.9e-05 21.9 0.5 0.00028 20.4 0.3 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH61055.1 - 0.0067 16.1 0.0 0.015 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCH61055.1 - 0.018 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3748 PF12566.3 CCH61055.1 - 0.025 14.5 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) Methyltransf_11 PF08241.7 CCH61055.1 - 0.039 14.4 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCH61055.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 CCH61056.1 - 5e-55 186.4 0.1 2e-54 184.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61056.1 - 3.1e-36 124.7 0.0 6.3e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61056.1 - 8.6e-05 21.6 1.0 0.00011 21.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like TrkH PF02386.11 CCH61057.1 - 5.9e-120 400.0 24.3 1.5e-118 395.4 8.3 2.2 2 0 0 2 2 2 2 Cation transport protein Zn_dep_PLPC PF00882.13 CCH61058.1 - 4.1e-17 62.3 1.8 8.2e-17 61.3 1.2 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C Mito_carr PF00153.22 CCH61059.1 - 1.4e-62 207.4 3.7 7.8e-21 73.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.16 CCH61060.1 - 4.5e-15 55.4 3.6 4.5e-15 55.4 2.5 1.9 3 0 0 3 3 3 1 PAP2 superfamily DUF454 PF04304.8 CCH61060.1 - 0.16 12.0 0.1 0.16 12.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF454) Fer4_5 PF12801.2 CCH61060.1 - 0.47 10.2 7.1 0.12 12.1 0.9 3.0 2 0 0 2 2 2 0 4Fe-4S binding domain DHC_N2 PF08393.8 CCH61061.1 - 4.2e-75 252.7 24.6 4.2e-75 252.7 17.1 6.5 6 1 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CCH61061.1 - 6.3e-51 173.4 52.4 6.3e-51 173.4 36.3 6.6 5 1 0 6 6 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CCH61061.1 - 1.4e-48 165.4 0.1 6.4e-48 163.2 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 CCH61061.1 - 8.2e-27 93.6 0.0 2e-07 30.8 0.0 6.4 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_9 PF12781.2 CCH61061.1 - 3.1e-25 88.3 2.7 3.1e-25 88.3 1.9 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CCH61061.1 - 8e-25 87.3 0.4 8e-25 87.3 0.3 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 MT PF12777.2 CCH61061.1 - 1.5e-24 86.4 4.8 4.3e-24 84.9 3.3 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.10 CCH61061.1 - 5.1e-22 77.7 0.7 5.1e-22 77.7 0.5 2.7 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA PF00004.24 CCH61061.1 - 5.9e-18 65.3 7.6 5.4e-05 23.4 0.0 7.2 7 0 0 7 7 6 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH61061.1 - 2.8e-14 53.3 10.0 0.00012 22.2 0.0 7.0 6 1 1 7 7 6 3 AAA domain Zeta_toxin PF06414.7 CCH61061.1 - 6.3e-09 35.2 0.0 0.074 12.1 0.0 3.7 3 0 0 3 3 3 3 Zeta toxin AAA_16 PF13191.1 CCH61061.1 - 4.4e-08 33.3 0.0 0.49 10.3 0.0 4.7 4 0 0 4 4 3 3 AAA ATPase domain AAA_33 PF13671.1 CCH61061.1 - 1.1e-06 28.5 0.0 0.0064 16.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CCH61061.1 - 1.3e-06 29.2 4.2 0.068 13.9 0.0 6.1 5 0 0 5 5 4 2 AAA domain AAA_19 PF13245.1 CCH61061.1 - 2.6e-06 27.1 0.2 0.28 10.9 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 CCH61061.1 - 3e-05 24.0 0.0 0.08 12.9 0.0 4.1 4 0 0 4 4 3 1 Sigma-54 interaction domain Sigma54_activat PF00158.21 CCH61061.1 - 3.2e-05 23.4 0.4 2.6 7.4 0.0 4.1 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_18 PF13238.1 CCH61061.1 - 3.3e-05 24.2 9.8 0.96 9.7 0.0 7.3 7 0 0 7 7 4 2 AAA domain RNA_helicase PF00910.17 CCH61061.1 - 5.1e-05 23.3 0.0 3.6 7.7 0.0 4.8 3 0 0 3 3 3 1 RNA helicase T2SE PF00437.15 CCH61061.1 - 6.6e-05 21.9 8.9 0.0098 14.8 0.1 3.7 4 0 0 4 4 3 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 CCH61061.1 - 0.00046 19.6 0.1 2.9 7.2 0.0 3.8 3 0 0 3 3 3 1 IstB-like ATP binding protein cobW PF02492.14 CCH61061.1 - 0.00062 19.2 0.7 0.068 12.6 0.0 3.2 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CCH61061.1 - 0.0019 17.8 0.0 10 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 CCH61061.1 - 0.012 14.8 0.1 0.66 9.1 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 CCH61061.1 - 0.017 14.6 0.0 5.4 6.4 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 CCH61061.1 - 0.045 13.2 0.8 4.1 7.0 0.0 3.5 4 0 0 4 4 2 0 P-loop containing region of AAA domain AAA_28 PF13521.1 CCH61061.1 - 0.064 13.2 0.0 34 4.3 0.0 3.9 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 CCH61061.1 - 0.37 10.2 0.2 1 8.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 CCH61061.1 - 2.5 7.4 3.0 6.7 6.0 0.0 3.2 4 0 0 4 4 4 0 AAA domain Ras PF00071.17 CCH61062.1 - 7.6e-36 122.9 0.0 1.1e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH61062.1 - 1.5e-16 60.9 0.1 4.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCH61062.1 - 2.1e-08 33.6 0.0 4.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCH61062.1 - 0.00061 19.0 0.1 0.0014 17.8 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 CCH61062.1 - 0.0015 18.1 0.6 0.0053 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCH61062.1 - 0.0053 16.8 0.0 0.018 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CCH61062.1 - 0.021 14.7 0.0 0.064 13.2 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 CCH61062.1 - 0.027 14.1 0.3 0.089 12.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CCH61062.1 - 0.029 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCH61062.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 CCH61062.1 - 0.073 12.7 4.2 0.52 9.9 2.8 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 CCH61062.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCH61062.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCH61062.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCH61062.1 - 0.41 10.9 13.9 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain tRNA_U5-meth_tr PF05958.6 CCH61063.1 - 3.5e-23 81.8 0.2 1.8e-22 79.5 0.1 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 CCH61063.1 - 5e-12 45.4 0.0 9.4e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 CCH61063.1 - 6.9e-10 38.7 0.3 1.6e-09 37.5 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CCH61063.1 - 1.4e-05 24.3 0.0 3.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCH61063.1 - 0.00013 22.4 0.0 0.00029 21.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH61063.1 - 0.00058 19.8 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH61063.1 - 0.00099 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CCH61063.1 - 0.0014 18.1 0.1 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 CCH61063.1 - 0.0016 18.0 0.0 0.0039 16.7 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 CCH61063.1 - 0.055 13.9 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S21e PF01249.13 CCH61064.1 - 1.5e-38 130.6 0.1 1.6e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_transf_8 PF01501.15 CCH61065.1 - 1e-29 103.6 4.9 1e-29 103.6 3.4 2.8 4 0 0 4 4 4 1 Glycosyl transferase family 8 DEAD PF00270.24 CCH61066.1 - 9.3e-43 145.6 1.9 4.8e-42 143.3 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61066.1 - 3.8e-28 97.1 0.1 1.5e-27 95.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH61066.1 - 5.4e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCH61066.1 - 0.0011 18.6 0.1 0.0042 16.8 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain DUF1253 PF06862.7 CCH61066.1 - 0.021 13.2 0.6 0.44 8.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Ribosomal_L10 PF00466.15 CCH61066.1 - 0.025 14.5 0.1 0.59 10.0 0.0 2.9 2 1 1 3 3 3 0 Ribosomal protein L10 Helicase_C_2 PF13307.1 CCH61066.1 - 0.026 14.5 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Glyco_transf_15 PF01793.11 CCH61067.1 - 2e-123 411.5 9.4 2.4e-123 411.3 6.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.20 CCH61068.1 - 4.3e-49 167.0 0.6 8.3e-49 166.0 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61068.1 - 7.1e-19 67.8 0.0 2.1e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCH61068.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCH61068.1 - 0.0015 17.8 0.1 0.0035 16.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family DUF1725 PF08333.6 CCH61068.1 - 0.12 11.6 1.6 0.44 9.9 1.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) BUD22 PF09073.5 CCH61068.1 - 0.98 8.4 16.2 1.8 7.5 11.2 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CCH61068.1 - 5.1 4.8 26.7 9.1 4.0 18.5 1.4 1 0 0 1 1 1 0 Nop14-like family Tim17 PF02466.14 CCH61069.1 - 8.9e-33 113.0 4.7 1e-32 112.8 3.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.19 CCH61071.1 - 9.4e-164 545.2 34.8 1.1e-163 545.0 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH61071.1 - 6.2e-35 120.5 41.6 2e-30 105.7 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH61071.1 - 0.005 15.0 1.6 0.005 15.0 1.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCH61072.1 - 4e-157 523.4 34.0 4.6e-157 523.2 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH61072.1 - 2.3e-35 121.9 48.4 5.8e-29 100.9 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexokinase_2 PF03727.11 CCH61074.1 - 3.5e-96 321.1 0.0 4.5e-96 320.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCH61074.1 - 1.9e-81 272.3 0.0 6.2e-81 270.6 0.0 1.7 2 0 0 2 2 2 1 Hexokinase Sec63 PF02889.11 CCH61075.1 - 3.4e-45 154.6 5.2 7.2e-45 153.5 3.6 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CCH61075.1 - 7.7e-29 100.3 0.0 2e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61075.1 - 1.1e-12 47.6 0.0 3.3e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH61075.1 - 4.4e-10 39.6 0.8 1.4e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCH61075.1 - 0.00022 21.3 0.0 0.0014 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCH61075.1 - 0.058 12.2 0.0 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 CCH61075.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2420 PF10336.4 CCH61076.1 - 2.1e-29 101.4 0.8 4.5e-29 100.3 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) AAA_14 PF13173.1 CCH61076.1 - 1.3 8.9 4.3 0.97 9.3 0.2 2.3 2 0 0 2 2 2 0 AAA domain Adap_comp_sub PF00928.16 CCH61077.1 - 1.1e-09 37.8 0.5 1.6e-09 37.2 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCH61077.1 - 6e-09 35.7 3.3 1.1e-08 34.9 1.0 2.1 2 0 0 2 2 2 1 Clathrin adaptor complex small chain NAD_binding_6 PF08030.7 CCH61077.1 - 6.4 6.6 8.9 8.9 6.1 4.2 2.8 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Proteasome PF00227.21 CCH61078.1 - 8.1e-27 93.7 0.2 9.7e-27 93.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit PDEase_II PF02112.10 CCH61079.1 - 8.9e-56 189.2 2.3 3.6e-33 114.9 0.1 2.5 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CCH61079.1 - 0.00053 19.5 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Brr6_like_C_C PF10104.4 CCH61080.1 - 1.2e-35 121.9 2.0 1.7e-35 121.4 1.4 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RAI1 PF08652.6 CCH61081.1 - 7.8e-27 92.8 0.1 1.5e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.16 CCH61082.1 - 4.4e-117 390.2 0.1 6e-117 389.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCH61082.1 - 1.6e-39 135.3 2.0 4.6e-39 133.8 0.6 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CCH61082.1 - 5e-06 26.9 0.0 1.8e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCH61082.1 - 2.8e-05 23.9 0.0 7.9e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCH61082.1 - 0.0048 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF155 PF02582.9 CCH61083.1 - 8.9e-60 201.5 0.1 1.6e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Plus-3 PF03126.13 CCH61084.1 - 4.3e-27 94.2 0.3 4.3e-27 94.2 0.2 2.7 3 0 0 3 3 3 1 Plus-3 domain DUF440 PF04269.7 CCH61084.1 - 0.062 13.3 0.2 0.062 13.3 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF440 A_deamin PF02137.13 CCH61085.1 - 2.1e-58 198.2 0.6 2.6e-58 197.9 0.4 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain IBN_N PF03810.14 CCH61086.1 - 1.5e-10 40.8 0.1 1.5e-08 34.4 0.1 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain APC10 PF03256.11 CCH61087.1 - 3.8e-45 153.8 0.7 5e-45 153.4 0.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.8 CCH61087.1 - 0.00021 21.0 1.3 0.001 18.8 0.3 2.3 2 0 0 2 2 2 1 PITH domain CBFB_NFYA PF02045.10 CCH61088.1 - 4.1e-24 84.8 6.3 7.3e-24 84.0 4.4 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PAT1 PF09770.4 CCH61088.1 - 1.1 7.4 7.9 1.1 7.3 5.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GARS_A PF01071.14 CCH61089.1 - 2.3e-78 262.2 0.0 3.7e-78 261.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CCH61089.1 - 5.9e-32 110.1 0.0 2.4e-31 108.1 0.0 2.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CCH61089.1 - 1e-30 106.7 0.0 1.9e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CCH61089.1 - 5.5e-22 77.7 0.0 1.7e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CCH61089.1 - 2.1e-16 59.9 2.9 5.5e-16 58.5 0.9 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 CCH61089.1 - 8.4e-08 31.3 0.0 6.4e-07 28.4 0.0 2.2 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCH61089.1 - 3.2e-07 30.2 0.0 1.2e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CCH61089.1 - 0.00015 21.2 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CCH61089.1 - 0.00023 20.5 0.0 0.00064 19.0 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 CCH61089.1 - 0.0013 18.6 0.0 0.0086 15.9 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.5 CCH61089.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 CCH61089.1 - 0.023 14.1 0.2 0.072 12.5 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCH61089.1 - 0.029 13.7 0.1 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.1 CCH61089.1 - 0.14 11.2 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Mito_carr PF00153.22 CCH61090.1 - 5.6e-39 131.7 4.5 4.3e-16 58.3 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein G0-G1_switch_2 PF15103.1 CCH61090.1 - 0.098 12.8 0.3 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 Sec15 PF04091.7 CCH61091.1 - 8.6e-102 340.6 15.8 8.6e-102 340.6 10.9 2.3 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like THUMP PF02926.12 CCH61092.1 - 3.4e-24 85.3 2.5 3.4e-24 85.3 1.7 1.8 1 1 1 2 2 2 1 THUMP domain DUF1077 PF06417.7 CCH61093.1 - 8e-46 154.4 2.6 1e-45 154.0 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) SAPS PF04499.10 CCH61095.1 - 4.8e-129 431.0 35.3 4.8e-129 431.0 24.5 3.9 2 2 0 3 3 3 1 SIT4 phosphatase-associated protein AdoHcyase PF05221.12 CCH61097.1 - 2.8e-140 465.8 0.0 3.2e-140 465.6 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CCH61097.1 - 2.9e-85 284.1 2.6 4.7e-85 283.3 1.8 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCH61097.1 - 1.9e-07 30.4 0.1 3.5e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CCH61097.1 - 0.00042 19.7 0.3 0.00079 18.8 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CCH61097.1 - 0.002 18.1 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CCH61097.1 - 0.029 13.9 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RPM2 PF08579.6 CCH61097.1 - 0.093 12.8 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) AlaDh_PNT_C PF01262.16 CCH61097.1 - 0.21 11.1 1.7 0.27 10.7 0.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SPRY PF00622.23 CCH61098.1 - 4.4e-18 65.5 1.3 1.8e-17 63.5 0.9 2.2 1 1 0 1 1 1 1 SPRY domain CLTH PF10607.4 CCH61098.1 - 2.1e-13 50.2 5.6 2.1e-13 50.2 3.9 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCH61098.1 - 0.032 14.0 0.4 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 LisH Daxx PF03344.10 CCH61098.1 - 0.13 10.7 51.8 0.0045 15.5 19.8 2.2 2 0 0 2 2 2 0 Daxx Family UPF0197 PF05251.7 CCH61099.1 - 0.0042 17.3 1.3 0.005 17.1 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) Claudin_2 PF13903.1 CCH61099.1 - 0.029 14.0 1.1 0.031 13.9 0.8 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2273 PF10031.4 CCH61099.1 - 0.19 11.3 1.6 0.4 10.3 1.1 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF202 PF02656.10 CCH61099.1 - 0.27 11.4 3.0 0.88 9.8 2.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) ADH_N PF08240.7 CCH61100.1 - 1.2e-26 92.5 4.8 2.8e-26 91.3 3.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH61100.1 - 2.2e-19 69.2 0.3 3.9e-19 68.4 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCH61100.1 - 0.0066 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCH61100.1 - 0.046 13.0 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 CCH61100.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 CCH61100.1 - 0.085 12.4 2.4 0.15 11.6 1.7 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IGFBP PF00219.13 CCH61100.1 - 1.6 9.2 6.4 1.7 9.2 0.9 2.4 2 0 0 2 2 2 0 Insulin-like growth factor binding protein GATA PF00320.22 CCH61101.1 - 7.7e-16 57.1 3.7 1.7e-15 56.0 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCH61101.1 - 2.9 7.2 6.4 0.21 10.9 0.4 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding UAA PF08449.6 CCH61102.1 - 1.6e-14 53.5 26.5 2e-14 53.2 18.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCH61102.1 - 5.1e-08 32.7 9.5 5.1e-08 32.7 6.6 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CCH61102.1 - 0.00046 19.3 6.3 0.00046 19.3 4.4 2.1 1 1 1 2 2 2 1 Nucleotide-sugar transporter PHO4 PF01384.15 CCH61102.1 - 0.27 9.8 12.2 0.024 13.2 1.2 2.9 2 1 0 2 2 2 0 Phosphate transporter family Multi_Drug_Res PF00893.14 CCH61102.1 - 2.2 8.7 13.9 0.27 11.7 3.8 2.8 3 0 0 3 3 3 0 Small Multidrug Resistance protein Nse5 PF08691.5 CCH61103.1 - 1.6e-13 50.0 29.2 2.8e-13 49.2 20.2 1.4 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 HAD_2 PF13419.1 CCH61104.1 - 1e-24 87.6 0.2 1.5e-24 87.1 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH61104.1 - 0.0016 18.9 0.0 0.011 16.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prefoldin_2 PF01920.15 CCH61105.1 - 4.2e-23 81.1 11.9 5e-23 80.8 8.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.6 CCH61105.1 - 0.0025 17.5 1.5 0.0057 16.4 0.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1192) Guanylin PF02058.10 CCH61105.1 - 0.019 14.9 0.5 0.031 14.3 0.3 1.4 1 1 0 1 1 1 0 Guanylin precursor Prefoldin_3 PF13758.1 CCH61105.1 - 0.021 14.5 5.9 0.34 10.7 4.0 2.2 1 1 0 1 1 1 0 Prefoldin subunit MscS_porin PF12795.2 CCH61105.1 - 0.025 13.9 0.4 0.025 13.9 0.3 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain ERM PF00769.14 CCH61105.1 - 0.048 13.1 5.2 0.07 12.6 3.6 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3221 PF11518.3 CCH61105.1 - 0.052 13.2 1.1 0.08 12.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) Spc24 PF08286.6 CCH61105.1 - 0.07 12.8 5.6 1.6 8.4 0.2 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cortex-I_coil PF09304.5 CCH61105.1 - 0.076 13.0 9.6 1.4 9.0 6.6 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil Stk19 PF10494.4 CCH61105.1 - 0.087 12.2 1.5 0.099 12.0 1.0 1.1 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 NPV_P10 PF05531.7 CCH61105.1 - 0.1 12.8 1.2 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ax_dynein_light PF10211.4 CCH61105.1 - 0.12 12.2 8.3 0.87 9.4 0.9 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain T4_neck-protein PF11649.3 CCH61105.1 - 0.13 11.5 1.8 0.16 11.2 1.3 1.2 1 0 0 1 1 1 0 Virus neck protein DUF4201 PF13870.1 CCH61105.1 - 0.3 10.5 7.7 0.96 8.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) BicD PF09730.4 CCH61105.1 - 0.39 8.9 8.3 0.78 8.0 5.7 1.4 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D FliJ PF02050.11 CCH61105.1 - 0.4 10.7 8.7 1.4 8.9 0.7 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Seryl_tRNA_N PF02403.17 CCH61105.1 - 0.48 10.4 10.2 1.1 9.3 1.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 CCH61105.1 - 0.53 9.9 9.1 4.5 6.9 6.3 2.1 1 1 0 1 1 1 0 Prefoldin subunit PEARLI-4 PF05278.7 CCH61105.1 - 0.77 9.0 8.1 0.9 8.8 1.1 2.0 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) AATF-Che1 PF13339.1 CCH61105.1 - 0.88 9.7 4.1 6.6 6.9 2.8 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Atg14 PF10186.4 CCH61105.1 - 0.99 8.2 6.8 1.4 7.8 4.7 1.2 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WASH-7_N PF14745.1 CCH61105.1 - 1.1 7.4 4.9 1.2 7.2 3.4 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal Tup_N PF08581.5 CCH61105.1 - 1.2 9.3 8.4 1.3 9.2 0.4 2.8 2 1 0 2 2 2 0 Tup N-terminal CENP-F_leu_zip PF10473.4 CCH61105.1 - 1.4 8.7 10.7 2.1 8.2 2.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 CCH61105.1 - 1.5 8.3 9.6 0.9 9.0 1.4 2.1 1 1 0 2 2 2 0 GrpE Tropomyosin_1 PF12718.2 CCH61105.1 - 1.6 8.5 9.8 5.4 6.8 6.8 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF4140 PF13600.1 CCH61105.1 - 1.8 9.0 4.2 12 6.4 2.9 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YgaB PF14182.1 CCH61105.1 - 2.9 8.1 10.7 0.2 11.9 1.8 2.3 1 1 1 2 2 2 0 YgaB-like protein Val_tRNA-synt_C PF10458.4 CCH61105.1 - 3.5 7.7 6.7 1.8 8.7 0.3 2.8 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DMPK_coil PF08826.5 CCH61105.1 - 3.6 7.5 8.7 1.2 9.1 1.3 2.6 2 1 0 2 2 2 0 DMPK coiled coil domain like THOC7 PF05615.8 CCH61105.1 - 4.3 7.6 10.5 5.1 7.3 1.6 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DUF4200 PF13863.1 CCH61105.1 - 4.4 7.2 12.3 0.83 9.6 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.1 CCH61105.1 - 7.5 6.5 9.2 3.6 7.5 0.7 2.3 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 COQ9 PF08511.6 CCH61106.1 - 5.9e-19 67.3 0.6 2.5e-18 65.3 0.4 2.0 2 0 0 2 2 2 1 COQ9 Cornichon PF03311.9 CCH61107.1 - 9.4e-47 158.3 11.3 1.1e-46 158.1 7.9 1.0 1 0 0 1 1 1 1 Cornichon protein CENP-X PF09415.5 CCH61108.1 - 1.6e-20 72.7 6.0 4.6e-20 71.1 4.1 1.7 1 1 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 CCH61108.1 - 0.00062 19.7 0.2 0.0014 18.6 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ENTH PF01417.15 CCH61109.1 - 3e-38 130.5 0.1 5.5e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 ENTH domain DUF1713 PF08213.6 CCH61110.1 - 2.1e-12 46.3 23.6 2.8e-12 46.0 16.4 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) zf-Mss51 PF13824.1 CCH61111.1 - 2.7e-17 62.3 0.9 4.9e-17 61.5 0.6 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 NOT2_3_5 PF04153.13 CCH61112.1 - 6.8e-33 113.4 1.7 6.8e-33 113.4 1.2 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family eIF-3c_N PF05470.7 CCH61112.1 - 0.015 13.4 6.7 0.018 13.1 4.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Vfa1 PF08432.5 CCH61112.1 - 0.016 15.2 12.2 0.026 14.5 8.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 F-protein PF00469.15 CCH61112.1 - 0.019 14.3 3.4 0.033 13.5 2.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Nop14 PF04147.7 CCH61112.1 - 0.093 10.6 22.8 0.12 10.2 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 CCH61112.1 - 0.34 8.9 9.7 0.47 8.4 6.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2201_N PF13203.1 CCH61112.1 - 0.75 8.9 8.3 1 8.4 5.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 CCH61112.1 - 0.76 9.6 4.2 1 9.1 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BTV_NS2 PF04514.7 CCH61112.1 - 0.79 8.5 10.8 1 8.1 7.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ndc1_Nup PF09531.5 CCH61112.1 - 1.1 7.6 6.9 1.4 7.2 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VirE2 PF07229.7 CCH61112.1 - 1.1 7.6 9.5 1.5 7.1 6.6 1.1 1 0 0 1 1 1 0 VirE2 CDC45 PF02724.9 CCH61112.1 - 1.6 6.7 16.6 2.2 6.2 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CCH61112.1 - 1.9 8.2 10.5 2.7 7.7 7.3 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 CCH61112.1 - 3.1 6.3 13.8 4.1 5.9 9.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 CCH61112.1 - 3.8 6.4 5.2 5.3 5.9 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ATP11 PF06644.6 CCH61112.1 - 9.2 5.6 12.1 15 4.9 8.4 1.2 1 0 0 1 1 1 0 ATP11 protein AAA_18 PF13238.1 CCH61113.1 - 1.9e-25 89.6 0.2 1.9e-25 89.6 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH61113.1 - 2.1e-12 47.9 0.9 3.8e-12 47.0 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CCH61113.1 - 0.00029 21.0 0.2 0.0019 18.4 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 CCH61113.1 - 0.00095 18.5 0.2 0.98 8.7 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 CCH61113.1 - 0.0013 17.8 0.0 0.0038 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CCH61113.1 - 0.0016 18.4 0.1 0.0035 17.3 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCH61113.1 - 0.0029 17.7 0.1 0.0058 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH61113.1 - 0.0051 16.6 0.1 0.68 9.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCH61113.1 - 0.0055 16.6 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCH61113.1 - 0.0078 15.4 0.1 0.034 13.3 0.0 1.9 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 CCH61113.1 - 0.013 15.3 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCH61113.1 - 0.015 15.4 0.2 0.063 13.4 0.0 2.0 2 1 1 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.13 CCH61113.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.9 CCH61113.1 - 0.12 12.0 0.1 0.41 10.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 CCH61113.1 - 0.25 11.6 3.8 4.8 7.4 2.7 2.1 1 1 0 1 1 1 0 ABC transporter Cyclin_N PF00134.18 CCH61114.1 - 1.6e-40 137.5 1.6 3.8e-40 136.3 1.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCH61114.1 - 3.4e-18 65.7 0.0 9.9e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CCH61115.1 - 1.9e-39 134.1 0.2 1e-38 131.7 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCH61115.1 - 2.9e-31 107.8 0.0 7.5e-31 106.5 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain IF-2B PF01008.12 CCH61116.1 - 2.5e-79 266.2 0.0 3e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ATP-synt_S1 PF05827.7 CCH61117.1 - 3.2e-06 26.6 1.2 5.4e-06 25.9 0.9 1.4 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) UPF0233 PF06781.7 CCH61117.1 - 0.097 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Pescadillo_N PF06732.6 CCH61118.1 - 1.4e-124 414.9 1.1 1.4e-124 414.9 0.8 2.5 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 CCH61118.1 - 3e-12 46.5 0.1 2.8e-11 43.4 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rhomboid PF01694.17 CCH61119.1 - 1.5e-29 102.9 17.2 1.5e-29 102.9 11.9 1.8 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.13 CCH61120.1 - 3.1e-55 186.9 0.9 8.8e-55 185.4 0.6 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CCH61120.1 - 1.9e-13 49.7 0.0 4.3e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 CCH61120.1 - 0.00013 21.5 2.1 0.01 15.6 0.2 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CCH61120.1 - 0.00028 20.9 1.7 0.00028 20.9 1.2 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CCH61120.1 - 0.018 14.3 0.7 0.16 11.3 0.1 2.8 2 0 0 2 2 2 0 EF hand Vps36_ESCRT-II PF11605.3 CCH61120.1 - 0.033 14.0 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Corona_NS2 PF04753.7 CCH61120.1 - 0.088 12.7 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Telomere_reg-2 PF10193.4 CCH61121.1 - 5.5e-22 78.1 1.0 1.8e-21 76.4 0.7 2.0 1 0 0 1 1 1 1 Telomere length regulation protein PH_BEACH PF14844.1 CCH61122.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH PH PF00169.24 CCH61123.1 - 5.6e-09 36.1 8.3 5.6e-09 36.1 5.8 2.8 2 1 0 2 2 2 1 PH domain FmrO PF07091.6 CCH61123.1 - 0.018 14.0 1.5 0.22 10.4 0.6 2.2 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) PX PF00787.19 CCH61124.1 - 3.6e-22 78.2 0.0 5.3e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 PX domain DUF4380 PF14315.1 CCH61124.1 - 0.067 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) CBFD_NFYB_HMF PF00808.18 CCH61125.1 - 1e-16 60.7 0.2 1.3e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCH61125.1 - 2.6e-07 30.6 0.5 3.5e-07 30.2 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3453 PF11935.3 CCH61126.1 - 1.7e-51 174.9 10.3 1.5e-37 129.3 0.7 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF3453) SR-25 PF10500.4 CCH61126.1 - 0.0053 16.2 11.5 0.0053 16.2 7.9 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CCH61126.1 - 0.0096 16.1 27.1 0.013 15.6 3.7 3.3 3 0 0 3 3 3 3 Cyclin-dependent kinase 2-associated protein DUF2360 PF10152.4 CCH61126.1 - 1.1 9.5 15.0 1.9 8.7 1.4 3.3 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Oxidored_FMN PF00724.15 CCH61127.1 - 1.9e-112 375.6 0.0 2.2e-112 375.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GCV_H PF01597.14 CCH61128.1 - 7.9e-44 148.2 0.6 9.4e-44 148.0 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CCH61128.1 - 0.0071 15.9 0.7 0.03 13.9 0.2 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme eIF2A PF08662.6 CCH61129.1 - 1.1e-23 83.9 2.2 3.8e-12 46.3 0.2 3.6 3 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CCH61129.1 - 4.9e-05 22.8 0.1 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH61129.1 - 0.00017 21.4 0.3 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CCH61129.1 - 0.0047 16.7 0.6 14 5.7 0.0 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Proteasome PF00227.21 CCH61130.1 - 3.8e-54 182.8 0.0 6.1e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH61130.1 - 9.5e-12 44.0 0.0 9.5e-12 44.0 0.0 2.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.13 CCH61131.1 - 1.8e-10 40.5 10.0 3.3e-10 39.6 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma54_DBD PF04552.8 CCH61131.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.6 3 0 0 3 3 3 0 Sigma-54, DNA binding domain Phage_GP20 PF06810.6 CCH61132.1 - 0.00019 20.9 5.4 0.00019 20.9 3.8 1.7 1 1 0 1 1 1 1 Phage minor structural protein GP20 Casc1 PF12366.3 CCH61132.1 - 0.0088 15.5 1.5 0.0088 15.5 1.1 1.7 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 Colicin_D PF11429.3 CCH61132.1 - 0.021 14.9 3.6 0.041 14.0 1.2 2.2 1 1 1 2 2 2 0 Colicin D DUF1027 PF06265.6 CCH61132.1 - 0.19 11.6 1.7 0.37 10.6 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) AMP-binding PF00501.23 CCH61133.1 - 1.5e-92 310.2 0.1 1.8e-92 309.9 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCH61133.1 - 1.4e-19 70.7 0.0 3.2e-18 66.4 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Kelch_6 PF13964.1 CCH61134.1 - 1.2e-10 41.1 2.1 0.057 13.6 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CCH61134.1 - 4e-07 29.4 7.9 0.4 10.2 0.3 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CCH61134.1 - 9.6e-05 22.0 5.8 0.12 12.1 0.2 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CCH61134.1 - 0.00022 20.8 4.7 1.7 8.5 0.3 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 CCH61134.1 - 0.00031 20.8 0.9 1.7 8.9 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CCH61134.1 - 0.0012 18.7 4.1 1.7 8.6 0.0 4.7 5 0 0 5 5 5 1 Kelch motif LRR_4 PF12799.2 CCH61136.1 - 5.2e-11 41.9 24.4 5.4e-06 25.9 2.4 6.8 3 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH61136.1 - 3.8e-06 26.5 18.0 0.00085 19.0 0.9 5.7 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CCH61136.1 - 0.00017 21.1 17.6 7.1 7.0 0.0 8.7 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 CCH61136.1 - 0.0051 16.7 12.3 36 5.1 0.0 8.0 8 0 0 8 8 8 0 Leucine rich repeat LRR_6 PF13516.1 CCH61136.1 - 0.0057 16.6 8.0 62 4.1 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich repeat WD40 PF00400.27 CCH61137.1 - 8.5e-37 123.7 16.0 4.9e-06 26.2 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 CCH61137.1 - 5e-05 23.1 0.2 0.27 10.9 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CCH61137.1 - 0.044 12.8 0.1 0.67 8.9 0.0 2.4 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Choline_kinase PF01633.15 CCH61137.1 - 0.072 12.6 0.2 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Patched PF02460.13 CCH61138.1 - 1.7e-31 109.0 34.7 5e-17 61.1 12.3 2.7 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 CCH61138.1 - 4.5e-27 94.3 8.0 4.5e-27 94.3 5.5 2.8 2 1 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Ly49 PF08391.5 CCH61138.1 - 0.044 13.9 2.8 0.11 12.6 0.8 2.5 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF446 PF04287.7 CCH61138.1 - 0.19 11.5 3.5 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 tRNA pseudouridine synthase C PT PF04886.7 CCH61139.1 - 3.2e-10 39.1 11.2 1.2e-06 27.7 0.7 10.0 2 2 3 5 5 5 4 PT repeat Arv1 PF04161.8 CCH61139.1 - 0.11 12.4 5.4 31 4.3 0.0 4.6 5 0 0 5 5 5 0 Arv1-like family Ogr_Delta PF04606.7 CCH61139.1 - 1.1 9.0 15.6 4.8 6.9 0.9 4.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger NADH-G_4Fe-4S_3 PF10588.4 CCH61139.1 - 1.7 7.9 7.2 31 3.9 0.1 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Prenyltrans PF00432.16 CCH61140.1 - 1.3e-52 174.9 5.7 7.8e-12 44.5 0.2 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCH61140.1 - 4.7e-34 117.1 0.0 2.4e-12 47.2 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCH61140.1 - 4.2e-09 36.3 0.0 4.1e-07 29.9 0.0 2.9 2 1 1 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 CCH61140.1 - 0.0017 17.6 0.0 0.67 9.1 0.0 3.2 4 0 0 4 4 4 2 A-macroglobulin complement component DNA_pol_E_B PF04042.11 CCH61141.1 - 1.2e-44 152.0 0.4 2.2e-44 151.1 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pepsin-I3 PF06394.8 CCH61141.1 - 0.069 12.8 0.8 3.9 7.1 0.1 3.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Nitr_red_bet_C PF14711.1 CCH61142.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal NBP1 PF08537.5 CCH61144.1 - 2.2e-47 161.8 39.0 2.1e-45 155.3 27.0 2.8 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 AAA PF00004.24 CCH61145.1 - 1.6e-43 148.0 0.0 3.4e-43 146.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCH61145.1 - 9.3e-31 105.5 0.1 8.7e-30 102.4 0.1 2.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CCH61145.1 - 2.8e-22 78.3 3.3 2.8e-22 78.3 2.3 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 CCH61145.1 - 3.1e-06 28.0 0.8 1.4e-05 25.9 0.0 2.5 3 1 0 3 3 1 1 AAA domain AAA_22 PF13401.1 CCH61145.1 - 4.1e-06 26.9 0.7 0.0011 19.1 0.1 3.2 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CCH61145.1 - 7.9e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCH61145.1 - 1.3e-05 25.1 0.0 5.1e-05 23.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CCH61145.1 - 1.9e-05 24.4 0.0 9.6e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCH61145.1 - 3.5e-05 23.2 0.0 7.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 CCH61145.1 - 3.8e-05 23.1 0.2 0.026 13.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 CCH61145.1 - 6.1e-05 22.0 0.0 0.00018 20.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CCH61145.1 - 7.2e-05 22.8 0.1 0.00066 19.7 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.8 CCH61145.1 - 0.00012 21.0 0.0 0.00022 20.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 CCH61145.1 - 0.00017 21.6 0.0 0.0072 16.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 CCH61145.1 - 0.00053 19.9 0.1 0.0029 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CCH61145.1 - 0.00072 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH61145.1 - 0.0022 18.2 0.3 0.0085 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCH61145.1 - 0.0091 15.1 0.1 0.11 11.5 0.0 2.5 1 1 2 3 3 3 1 Zeta toxin AAA_24 PF13479.1 CCH61145.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 CCH61145.1 - 0.02 14.7 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 Torsin KaiC PF06745.8 CCH61145.1 - 0.025 13.6 0.7 4.6 6.2 0.0 2.5 2 1 1 3 3 2 0 KaiC Mg_chelatase PF01078.16 CCH61145.1 - 0.027 13.6 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCH61145.1 - 0.034 13.3 0.1 0.082 12.1 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 CCH61145.1 - 0.037 13.7 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CCH61145.1 - 0.038 13.6 0.0 0.5 10.0 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 CCH61145.1 - 0.075 12.5 0.0 0.28 10.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCH61145.1 - 0.078 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCH61145.1 - 0.078 13.0 0.1 0.23 11.5 0.0 1.8 2 1 0 2 2 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 CCH61145.1 - 0.078 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 CCH61145.1 - 0.091 12.4 2.2 0.46 10.1 0.0 2.7 3 1 1 4 4 3 0 Archaeal ATPase CPT PF07931.7 CCH61145.1 - 0.1 12.2 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PWWP PF00855.12 CCH61146.1 - 4.3e-18 65.2 1.1 1.6e-17 63.4 0.0 2.6 2 0 0 2 2 2 1 PWWP domain DUF4604 PF15377.1 CCH61146.1 - 0.73 10.0 23.8 0.93 9.6 10.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Thymidylat_synt PF00303.14 CCH61147.1 - 2.1e-119 397.4 0.0 2.4e-119 397.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.6 CCH61148.1 - 4.2e-12 45.5 9.9 3.1e-11 42.7 6.6 2.6 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 CCH61148.1 - 1.3e-07 30.9 10.6 1.3e-07 30.9 7.4 2.2 2 0 0 2 2 2 1 Shugoshin C terminus A2L_zn_ribbon PF08792.5 CCH61148.1 - 0.14 11.6 0.3 0.26 10.7 0.2 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain TSC22 PF01166.13 CCH61148.1 - 1.5 8.8 6.4 0.75 9.7 1.4 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family Nucleoporin_C PF03177.9 CCH61149.1 - 2.6e-56 191.3 31.1 4.7e-56 190.5 21.5 1.5 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCH61149.1 - 1.4e-40 139.3 9.7 2.6e-40 138.4 6.7 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Brix PF04427.13 CCH61150.1 - 1.8e-36 125.5 0.5 2.5e-36 125.1 0.4 1.2 1 0 0 1 1 1 1 Brix domain RabGAP-TBC PF00566.13 CCH61151.1 - 3.6e-50 170.4 4.2 3.6e-50 170.4 2.9 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF939_C PF11728.3 CCH61151.1 - 0.11 12.3 1.4 0.22 11.3 1.0 1.5 1 0 0 1 1 1 0 DUF939 C-terminal domain Lactamase_B_2 PF12706.2 CCH61152.1 - 1.2e-34 119.5 2.0 1.2e-34 119.5 0.2 1.9 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CCH61152.1 - 6.2e-23 80.0 0.0 1.7e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CCH61152.1 - 0.027 14.1 0.3 0.063 12.9 0.1 1.7 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Vps5 PF09325.5 CCH61153.1 - 2.1e-65 220.2 11.3 2.1e-65 220.2 7.9 2.0 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 CCH61153.1 - 2.2e-22 79.0 0.5 1.5e-21 76.2 0.0 2.6 3 0 0 3 3 3 1 PX domain Ribosomal_L3 PF00297.17 CCH61154.1 - 2.5e-120 400.7 7.2 3e-120 400.5 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Lum_binding PF00677.12 CCH61155.1 - 0.014 15.2 0.3 0.73 9.7 0.0 2.7 2 1 0 2 2 2 0 Lumazine binding domain Cellulase PF00150.13 CCH61156.1 - 5.8e-15 55.2 6.3 1.3e-14 54.1 4.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1708 PF08101.6 CCH61157.1 - 8.3e-150 499.2 12.6 8.3e-150 499.2 8.7 2.6 3 1 0 3 3 3 1 Domain of unknown function (DUF1708) Ras PF00071.17 CCH61158.1 - 4.4e-50 169.2 0.0 5.4e-50 168.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH61158.1 - 8.6e-17 61.7 0.0 1.9e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCH61158.1 - 3.2e-11 42.7 0.0 4.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CCH61158.1 - 0.0008 19.5 0.2 0.0069 16.5 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CCH61158.1 - 0.0029 16.7 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region KaiC PF06745.8 CCH61158.1 - 0.023 13.8 0.3 0.035 13.2 0.2 1.2 1 0 0 1 1 1 0 KaiC Pox_A32 PF04665.7 CCH61158.1 - 0.028 13.7 0.1 0.05 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 CCH61158.1 - 0.04 14.0 0.2 0.19 11.8 0.1 2.0 1 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 CCH61158.1 - 0.045 12.9 0.0 0.076 12.2 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCH61158.1 - 0.063 11.9 3.0 1.3 7.6 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 CCH61158.1 - 0.065 13.1 0.2 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCH61158.1 - 0.091 12.4 0.2 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 NACHT domain TPR_11 PF13414.1 CCH61159.1 - 0.00039 20.0 0.1 0.0054 16.3 0.0 2.4 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 CCH61159.1 - 0.0023 18.2 0.2 0.0055 17.0 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61159.1 - 0.0076 16.0 0.1 0.064 13.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCH61159.1 - 0.014 15.9 0.1 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCH61159.1 - 0.037 14.7 0.0 0.26 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat IF-2B PF01008.12 CCH61160.1 - 1.1e-76 257.5 0.2 4.3e-76 255.5 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NAAA-beta PF15508.1 CCH61160.1 - 0.042 14.2 0.2 0.27 11.6 0.0 2.3 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fes1 PF08609.5 CCH61160.1 - 0.055 13.9 1.0 0.12 12.8 0.7 1.6 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 NAD_binding_10 PF13460.1 CCH61161.1 - 3e-14 53.4 0.0 4.2e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 CCH61161.1 - 7.7e-07 28.7 0.0 1e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCH61161.1 - 3.9e-05 22.7 0.0 0.00015 20.7 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CCH61161.1 - 5.2e-05 22.0 0.0 0.00037 19.2 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CCH61161.1 - 8.6e-05 22.5 0.0 0.0014 18.6 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase NmrA PF05368.8 CCH61161.1 - 0.00027 20.2 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 CCH61161.1 - 0.08 11.8 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Ribosomal_S30 PF04758.9 CCH61162.1 - 6.8e-30 102.6 5.0 8e-30 102.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.1 CCH61163.1 - 8.7e-09 34.9 3.3 8.7e-09 34.9 2.3 2.0 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting DUF3510 PF12022.3 CCH61163.1 - 0.0062 16.6 2.2 0.019 15.0 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Pol_alpha_B_N PF08418.5 CCH61163.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal ABC_trans_N PF14510.1 CCH61163.1 - 0.13 12.3 4.0 0.71 10.0 0.1 2.9 3 0 0 3 3 3 0 ABC-transporter extracellular N-terminal WH1 PF00568.18 CCH61164.1 - 1.6e-34 117.9 0.0 2.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CCH61164.1 - 4e-05 23.0 1.2 8.2e-05 22.0 0.5 1.9 2 0 0 2 2 2 1 WH2 motif Glyco_hydro_18 PF00704.23 CCH61165.1 - 1.4e-21 77.3 1.6 6.3e-21 75.1 1.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 CCH61165.1 - 1.1e-08 34.6 3.4 1.1e-08 34.6 2.4 4.6 4 1 1 5 5 5 1 Carbohydrate binding domain (family 19) DUF1199 PF06712.6 CCH61165.1 - 0.68 9.8 3.9 0.63 9.8 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1199) Dicty_REP PF05086.7 CCH61165.1 - 9.7 3.7 10.3 14 3.3 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Methyltransf_16 PF10294.4 CCH61166.1 - 3.7e-12 46.0 0.0 1.9e-11 43.6 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCH61166.1 - 0.00037 20.2 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCH61166.1 - 0.0054 15.8 0.0 0.0096 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCH61166.1 - 0.034 14.7 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ECH PF00378.15 CCH61167.1 - 3.2e-15 55.9 0.0 3.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 CCH61168.1 - 2e-14 53.3 0.0 2.6e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Gon7 PF08738.5 CCH61169.1 - 0.1 12.5 2.0 0.23 11.4 1.4 1.6 1 0 0 1 1 1 0 Gon7 family RF-1 PF00472.15 CCH61170.1 - 9.9e-21 73.6 5.9 2.5e-20 72.3 4.0 1.7 1 1 0 1 1 1 1 RF-1 domain DUF2562 PF10814.3 CCH61170.1 - 0.59 10.0 2.4 0.54 10.2 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) Fungal_trans PF04082.13 CCH61171.1 - 3e-11 42.6 0.3 6.3e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH61171.1 - 3e-05 23.8 11.0 3e-05 23.8 7.6 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_21 PF03370.8 CCH61172.1 - 1e-22 80.2 14.7 1e-22 80.2 10.2 2.5 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit PBP_sp32 PF07222.7 CCH61172.1 - 1e-05 24.8 14.5 2.5e-05 23.5 10.0 1.6 1 0 0 1 1 1 1 Proacrosin binding protein sp32 TP53IP5 PF15331.1 CCH61172.1 - 0.26 11.1 10.7 0.74 9.6 7.4 1.7 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Tim54 PF11711.3 CCH61172.1 - 0.54 8.8 12.3 1.6 7.2 8.5 1.8 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF853 PF05872.7 CCH61172.1 - 1.7 6.8 5.5 2.6 6.2 3.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Med15 PF09606.5 CCH61172.1 - 3.5 5.7 38.5 0.061 11.5 13.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sec62 PF03839.11 CCH61172.1 - 7.3 5.9 13.1 17 4.7 9.1 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 PTR2 PF00854.16 CCH61173.1 - 2.1e-55 188.0 19.1 2.9e-55 187.5 11.6 2.2 1 1 1 2 2 2 2 POT family MFS_1 PF07690.11 CCH61173.1 - 2.2e-09 36.5 10.8 1e-07 31.0 2.5 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF897 PF05982.7 CCH61173.1 - 0.0031 16.3 0.0 0.032 13.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF897) SET PF00856.23 CCH61175.1 - 4.8e-09 36.7 0.5 1.2e-08 35.4 0.3 2.0 2 1 0 2 2 2 1 SET domain Cofilin_ADF PF00241.15 CCH61176.1 - 2.4e-43 147.0 0.8 2.7e-43 146.8 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 CCH61176.1 - 0.00018 21.4 0.2 0.00032 20.6 0.1 1.4 2 0 0 2 2 2 1 Carbohydrate binding domain WIYLD PF10440.4 CCH61177.1 - 0.098 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain NPV_P10 PF05531.7 CCH61177.1 - 1.2 9.4 4.5 0.56 10.4 0.2 2.5 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RRM_1 PF00076.17 CCH61179.1 - 1.8e-14 53.0 5.2 4e-06 26.3 1.4 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH61179.1 - 6.8e-10 38.7 0.9 0.00052 19.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH61179.1 - 0.076 12.8 0.1 8.2 6.3 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tom22 PF04281.8 CCH61179.1 - 5.4 6.5 9.1 9 5.8 6.3 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PITH PF06201.8 CCH61180.1 - 3.3e-34 117.8 2.9 4.2e-34 117.5 2.0 1.1 1 0 0 1 1 1 1 PITH domain PWI PF01480.12 CCH61182.1 - 0.011 15.7 1.5 0.011 15.7 1.0 2.8 3 0 0 3 3 3 0 PWI domain Inhibitor_I29 PF08246.7 CCH61182.1 - 6 7.2 12.5 8.3 6.7 0.5 4.3 4 1 0 4 4 4 0 Cathepsin propeptide inhibitor domain (I29) PALP PF00291.20 CCH61183.1 - 1.7e-60 204.8 0.0 2e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CTP_transf_2 PF01467.21 CCH61184.1 - 9.4e-36 123.2 0.1 2e-35 122.1 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase CTP_transf_2 PF01467.21 CCH61185.1 - 1.3e-19 70.7 0.4 4.9e-15 55.9 0.1 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CCH61185.1 - 0.0061 16.1 1.2 0.69 9.5 0.1 3.1 2 1 0 2 2 2 1 FAD synthetase DUF4112 PF13430.1 CCH61186.1 - 1.3e-31 108.6 0.2 1.8e-31 108.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) COQ7 PF03232.8 CCH61186.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Pex24p PF06398.6 CCH61187.1 - 9.2e-88 294.4 11.5 1.2e-87 294.0 8.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-CCCH PF00642.19 CCH61188.1 - 9.7e-09 34.7 3.6 2.2e-08 33.5 2.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 CCH61188.1 - 1.4e-06 28.0 7.2 2.8e-06 27.0 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCH61188.1 - 1.9e-05 24.3 11.6 3.5e-05 23.4 8.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCH61188.1 - 1.9e-05 24.5 12.4 1.9e-05 24.5 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH61188.1 - 4.6e-05 22.9 13.4 0.00011 21.7 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH61188.1 - 8.6e-05 22.1 8.0 0.00015 21.3 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CCH61188.1 - 0.00048 19.5 7.5 0.0011 18.4 5.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CCH61188.1 - 0.0013 18.4 3.7 0.0027 17.4 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 CCH61188.1 - 0.036 13.5 7.5 0.071 12.6 5.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 CCH61188.1 - 0.065 12.7 7.4 0.13 11.8 5.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-CCCH_2 PF14608.1 CCH61188.1 - 0.25 11.3 4.6 0.73 9.9 3.2 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type zf-C3HC4_4 PF15227.1 CCH61188.1 - 0.31 10.9 14.6 0.13 12.2 6.9 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCH61188.1 - 0.34 10.6 6.8 1.2 8.8 4.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 CCH61188.1 - 0.75 9.6 6.7 1.8 8.4 4.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_L40e PF01020.12 CCH61188.1 - 1.3 8.6 9.8 0.38 10.3 4.2 2.1 2 0 0 2 2 2 0 Ribosomal L40e family DUF4428 PF14471.1 CCH61188.1 - 7.4 6.3 15.7 1.5 8.6 5.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Telomerase_RBD PF12009.3 CCH61189.1 - 2.3e-31 108.4 9.5 2.3e-31 108.4 6.6 3.0 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CCH61189.1 - 1.1e-09 37.9 4.5 3.5e-09 36.3 1.5 2.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Vps8 PF12816.2 CCH61190.1 - 2.7e-36 124.6 7.4 2.7e-36 124.6 5.1 2.7 4 0 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 zf-rbx1 PF12678.2 CCH61190.1 - 0.0058 16.7 1.8 0.0058 16.7 1.3 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCH61190.1 - 0.0081 15.9 2.2 0.0081 15.9 1.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CCH61190.1 - 0.0085 15.7 3.8 0.0085 15.7 2.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Clathrin PF00637.15 CCH61190.1 - 0.012 15.2 30.3 0.15 11.6 0.2 5.7 5 1 0 5 5 5 0 Region in Clathrin and VPS zf-C3HC4 PF00097.20 CCH61190.1 - 0.015 14.9 3.3 0.053 13.1 2.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) B-block_TFIIIC PF04182.7 CCH61191.1 - 7.1e-16 57.8 0.5 3.8e-15 55.4 0.0 2.6 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC CTD_bind PF04818.8 CCH61191.1 - 0.012 15.8 0.4 17 5.7 0.1 3.8 3 0 0 3 3 3 0 RNA polymerase II-binding domain. MarR_2 PF12802.2 CCH61191.1 - 0.026 14.1 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 MarR family N6-adenineMlase PF10237.4 CCH61192.1 - 3e-61 205.8 0.1 4.3e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Ribosomal_L7Ae PF01248.21 CCH61193.1 - 6.8e-23 80.0 0.2 1.4e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCH61193.1 - 0.006 16.4 0.1 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.11 CCH61194.1 - 3.1e-63 212.9 0.3 1e-62 211.3 0.2 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCH61194.1 - 4.2e-43 147.4 0.0 6.7e-35 120.5 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 CCH61195.1 - 5e-58 196.2 7.2 8.4e-58 195.5 5.0 1.3 1 0 0 1 1 1 1 Major intrinsic protein Nnf1 PF03980.9 CCH61196.1 - 1.7e-12 47.2 2.8 4e-12 46.0 0.4 2.2 2 1 0 2 2 2 1 Nnf1 bZIP_1 PF00170.16 CCH61196.1 - 0.1 12.5 0.6 0.1 12.5 0.4 2.7 3 0 0 3 3 3 0 bZIP transcription factor Pup PF05639.6 CCH61196.1 - 1.4 9.5 4.7 14 6.2 0.0 2.7 2 1 0 2 2 2 0 Pup-like protein MIP PF00230.15 CCH61197.1 - 9.3e-73 244.4 5.4 1.5e-72 243.7 3.8 1.3 1 0 0 1 1 1 1 Major intrinsic protein Gal_mutarotas_2 PF13802.1 CCH61197.1 - 0.11 12.3 0.2 7.5 6.4 0.1 2.7 2 0 0 2 2 2 0 Galactose mutarotase-like Autophagy_act_C PF03987.10 CCH61198.1 - 1.1e-07 31.8 1.4 2.5e-07 30.7 0.2 2.2 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.1 CCH61199.1 - 1.7e-33 114.6 0.0 3e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCH61199.1 - 1.6e-10 41.1 7.8 1.6e-10 41.1 5.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCH61199.1 - 7.7e-09 35.4 6.2 7.7e-09 35.4 4.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCH61199.1 - 7.1e-05 22.9 4.8 0.035 14.3 0.2 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCH61199.1 - 0.00015 22.0 3.2 0.00015 22.0 2.2 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.22 CCH61199.1 - 0.00065 19.4 4.3 0.0045 16.7 0.8 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_10 PF13237.1 CCH61199.1 - 0.016 14.9 9.9 0.016 14.9 6.9 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCH61199.1 - 0.99 9.8 15.0 0.082 13.2 5.8 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 CCH61199.1 - 3.6 8.2 8.0 1.1 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF1162 PF06650.7 CCH61200.1 - 2e-46 158.4 1.9 5.2e-44 150.5 0.4 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCH61200.1 - 7.7e-25 86.7 0.1 3.6e-24 84.5 0.1 2.3 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Ecm29 PF13001.2 CCH61201.1 - 1.4e-128 429.5 0.1 1.4e-128 429.5 0.1 2.9 3 1 1 4 4 4 1 Proteasome stabiliser HEAT PF02985.17 CCH61201.1 - 5.2e-18 63.4 3.3 0.014 15.3 0.0 9.9 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 CCH61201.1 - 8.3e-08 32.5 3.1 0.031 14.6 0.0 6.7 4 3 3 7 7 7 2 Vacuolar 14 Fab1-binding region WSC PF01822.14 CCH61202.1 - 7.2e-11 41.8 18.0 7.2e-11 41.8 12.5 2.9 3 0 0 3 3 3 1 WSC domain DUF912 PF06024.7 CCH61202.1 - 6 6.9 7.7 1.9 8.5 0.0 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AAA PF00004.24 CCH61203.1 - 2.4e-93 309.2 0.0 2.5e-47 160.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCH61203.1 - 2.2e-15 56.3 0.0 2.8e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCH61203.1 - 1.1e-11 45.5 0.0 3.2e-06 27.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CCH61203.1 - 1.4e-11 44.7 1.1 0.00028 20.9 0.0 3.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 CCH61203.1 - 2.2e-10 40.7 0.1 0.0066 16.5 0.0 4.6 3 2 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 CCH61203.1 - 2.6e-10 39.7 0.0 0.00078 18.5 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_33 PF13671.1 CCH61203.1 - 7.1e-10 38.9 0.0 0.00029 20.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCH61203.1 - 7.4e-10 39.0 0.0 0.00085 19.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CCH61203.1 - 8.6e-10 38.6 0.0 0.0028 17.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CCH61203.1 - 1.8e-09 37.4 0.2 0.0013 18.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CCH61203.1 - 1.5e-08 34.9 4.4 3.3e-05 24.1 0.0 3.8 4 0 0 4 4 3 2 AAA domain TIP49 PF06068.8 CCH61203.1 - 1.7e-08 33.6 0.0 0.00047 18.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 CCH61203.1 - 3.3e-07 30.4 0.0 0.028 14.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 CCH61203.1 - 3.5e-07 30.6 0.0 0.014 15.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter IstB_IS21 PF01695.12 CCH61203.1 - 6.9e-07 28.8 0.2 0.023 14.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CCH61203.1 - 7.9e-07 28.7 0.6 0.056 13.2 0.1 2.8 3 0 0 3 3 2 2 Part of AAA domain AAA_28 PF13521.1 CCH61203.1 - 1.6e-06 28.2 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CCH61203.1 - 3.1e-06 26.5 0.1 0.044 12.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 CCH61203.1 - 3.4e-06 26.8 0.9 0.0016 18.2 0.1 3.2 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Cytidylate_kin2 PF13189.1 CCH61203.1 - 4.5e-06 26.6 0.1 0.0005 20.0 0.0 2.8 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_3 PF07726.6 CCH61203.1 - 6.8e-06 25.7 0.0 0.051 13.1 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCH61203.1 - 8.3e-06 24.7 0.2 0.031 12.9 0.0 3.1 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CCH61203.1 - 1.1e-05 24.9 2.9 0.75 9.1 0.0 4.3 2 2 2 5 5 5 1 AAA domain SRPRB PF09439.5 CCH61203.1 - 1.2e-05 24.5 0.0 2.1 7.5 0.0 3.8 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit NACHT PF05729.7 CCH61203.1 - 1.5e-05 24.6 0.1 0.53 9.9 0.0 3.7 4 0 0 4 4 4 2 NACHT domain Arch_ATPase PF01637.13 CCH61203.1 - 7.2e-05 22.5 0.0 1.8 8.2 0.0 4.0 3 1 1 4 4 4 2 Archaeal ATPase SKI PF01202.17 CCH61203.1 - 8.9e-05 22.4 3.2 0.07 13.0 0.0 3.3 4 0 0 4 4 2 2 Shikimate kinase Sigma54_activ_2 PF14532.1 CCH61203.1 - 0.00011 22.3 0.0 0.69 9.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 CCH61203.1 - 0.00029 20.3 0.0 0.26 10.7 0.0 2.9 2 1 1 3 3 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CCH61203.1 - 0.00034 20.1 0.0 0.95 8.9 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CCH61203.1 - 0.00035 19.5 0.0 0.34 9.7 0.0 2.9 3 0 0 3 3 2 1 NB-ARC domain DUF815 PF05673.8 CCH61203.1 - 0.00044 19.2 0.0 0.14 11.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CPT PF07931.7 CCH61203.1 - 0.0014 18.2 0.0 0.027 14.0 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 CCH61203.1 - 0.0015 17.6 0.0 1.3 8.1 0.0 3.1 3 0 0 3 3 3 1 KaiC ATP-synt_ab PF00006.20 CCH61203.1 - 0.0016 17.9 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 CCH61203.1 - 0.0023 16.8 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CCH61203.1 - 0.0026 17.3 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCH61203.1 - 0.0061 15.8 0.1 1.7 7.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein UPF0079 PF02367.12 CCH61203.1 - 0.012 15.2 0.0 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 CCH61203.1 - 0.015 14.9 0.0 4.4 6.9 0.0 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 CCH61203.1 - 0.019 14.4 0.0 7 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.1 CCH61203.1 - 0.029 13.9 7.3 0.42 10.1 0.0 3.5 3 1 0 3 3 2 0 AAA domain AFG1_ATPase PF03969.11 CCH61203.1 - 0.035 12.9 0.1 3.9 6.1 0.0 2.6 2 1 0 2 2 2 0 AFG1-like ATPase MMR_HSR1 PF01926.18 CCH61203.1 - 0.043 13.7 0.1 3.8 7.4 0.0 3.2 2 1 1 3 3 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 CCH61203.1 - 0.053 12.7 0.0 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCH61203.1 - 0.066 12.4 0.1 2.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 CCH61203.1 - 0.12 11.9 0.0 6.4 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CCH61203.1 - 0.16 11.5 0.0 20 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 CCH61203.1 - 0.23 10.6 0.6 19 4.3 0.0 2.7 3 0 0 3 3 3 0 Isopentenyl transferase DUF2456 PF10445.4 CCH61204.1 - 2.8e-20 72.0 2.5 6.8e-20 70.7 1.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) DUF605 PF04652.11 CCH61204.1 - 2.6e-05 23.8 7.1 2.6e-05 23.8 4.9 2.3 1 1 1 2 2 2 1 Vta1 like Borrelia_P83 PF05262.6 CCH61205.1 - 0.34 9.1 29.6 0.54 8.4 20.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_tranf_2_5 PF13712.1 CCH61205.1 - 2 7.6 6.8 0.25 10.5 1.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase like family SprA-related PF12118.3 CCH61205.1 - 6.6 5.9 24.7 0.81 8.9 13.8 1.8 2 0 0 2 2 2 0 SprA-related family Peptidase_M24 PF00557.19 CCH61207.1 - 1.6e-37 129.1 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCH61207.1 - 6.4e-11 42.8 0.0 4.5e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain DUF3896 PF13035.1 CCH61207.1 - 2.9e-05 24.0 2.3 0.075 13.1 0.1 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3896) MFS_1 PF07690.11 CCH61208.1 - 5.1e-42 143.8 28.5 5.1e-42 143.8 19.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH61208.1 - 3.3e-11 42.4 19.1 7.5e-11 41.2 13.2 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 CCH61208.1 - 0.00013 20.3 2.0 0.00021 19.6 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M56 PF05569.6 CCH61208.1 - 0.065 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Fe-S_biosyn PF01521.15 CCH61209.1 - 2.1e-18 66.2 0.0 5.4e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NPR3 PF03666.8 CCH61210.1 - 2.1e-142 474.8 13.8 2.1e-142 474.8 9.6 3.2 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 Enolase_C PF00113.17 CCH61211.1 - 3.9e-140 465.9 0.0 5.1e-140 465.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCH61211.1 - 1.5e-55 186.7 0.2 2.4e-55 186.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CCH61211.1 - 0.00012 22.0 0.2 0.00039 20.3 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like Septin PF00735.13 CCH61212.1 - 7e-103 343.5 2.6 7e-103 343.5 1.8 2.1 2 0 0 2 2 2 1 Septin DUF258 PF03193.11 CCH61212.1 - 6.5e-05 22.1 0.0 0.00015 20.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCH61212.1 - 0.00011 21.7 4.2 0.00031 20.2 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CCH61212.1 - 0.00013 22.2 3.8 0.0068 16.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 CCH61212.1 - 0.00042 20.2 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCH61212.1 - 0.0015 18.5 0.1 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCH61212.1 - 0.0019 18.3 0.7 0.0081 16.3 0.0 2.4 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.11 CCH61212.1 - 0.0096 15.0 0.0 0.0096 15.0 0.0 2.0 2 0 0 2 2 2 1 AIG1 family DUF342 PF03961.8 CCH61212.1 - 0.011 14.2 9.5 0.017 13.5 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_10 PF12846.2 CCH61212.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.9 2 1 0 2 2 2 0 AAA-like domain DUF2317 PF10079.4 CCH61212.1 - 0.017 13.7 8.0 0.025 13.1 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) AAA_29 PF13555.1 CCH61212.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CCH61212.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 CCH61212.1 - 0.19 10.3 10.4 4.3 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF883 PF05957.8 CCH61212.1 - 0.56 10.6 4.9 1.1 9.6 3.4 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 CCH61212.1 - 0.56 9.7 12.1 0.98 8.9 8.4 1.3 1 0 0 1 1 1 0 IncA protein Exonuc_VII_L PF02601.10 CCH61212.1 - 0.75 8.9 10.3 1.3 8.1 7.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_18 PF13238.1 CCH61212.1 - 3.5 7.9 7.3 0.74 10.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF4559 PF15112.1 CCH61212.1 - 4.5 6.3 17.2 0.013 14.6 5.0 1.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4559) Dynamin_N PF00350.18 CCH61212.1 - 8.2 6.2 10.2 1.4 8.7 0.6 3.1 2 1 0 2 2 2 0 Dynamin family RasGEF PF00617.14 CCH61213.1 - 7.2e-56 188.9 0.5 2.6e-55 187.0 0.1 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCH61213.1 - 9.3e-18 64.2 0.5 9.3e-18 64.2 0.3 4.0 5 0 0 5 5 5 1 RasGEF N-terminal motif SH3_9 PF14604.1 CCH61213.1 - 2.4e-07 30.2 0.0 9e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CCH61213.1 - 1.7e-06 27.2 0.0 5e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCH61213.1 - 8.1e-06 25.2 0.0 1.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UQ_con PF00179.21 CCH61214.1 - 2.9e-35 120.7 0.0 2.9e-35 120.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CCH61214.1 - 0.0071 16.0 1.0 0.029 14.0 0.3 2.1 1 1 1 2 2 2 1 UEV domain Prok-E2_B PF14461.1 CCH61214.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B PALP PF00291.20 CCH61215.1 - 3.5e-60 203.8 0.0 4.8e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CCH61215.1 - 9.3e-14 50.9 0.0 9e-09 34.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain GAD PF02938.9 CCH61215.1 - 0.0027 17.8 0.2 7 6.8 0.1 3.3 3 0 0 3 3 3 2 GAD domain GHMP_kinases_C PF08544.8 CCH61215.1 - 0.0037 17.4 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal ALAD PF00490.16 CCH61216.1 - 1.5e-115 385.5 0.0 1.7e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase HSP70 PF00012.15 CCH61217.1 - 3.2e-272 903.8 8.5 3.6e-272 903.6 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH61217.1 - 4.5e-18 64.9 0.2 1.1e-16 60.3 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.11 CCH61217.1 - 0.00037 20.1 0.0 0.00079 19.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CCH61217.1 - 0.0054 15.5 0.2 0.034 12.9 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain S-AdoMet_synt_M PF02772.11 CCH61217.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain Hydantoinase_A PF01968.13 CCH61217.1 - 0.069 12.2 1.9 0.18 10.8 0.0 2.4 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase PMBR PF09373.5 CCH61217.1 - 1.2 9.1 4.5 2.3 8.2 0.0 3.1 4 0 0 4 4 4 0 Pseudomurein-binding repeat UPF0121 PF03661.8 CCH61218.1 - 3.9e-14 52.4 8.1 7e-14 51.6 5.6 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_12 PF13424.1 CCH61219.1 - 5.6e-08 32.6 3.1 1.7e-06 27.8 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61219.1 - 5.6e-07 29.0 2.1 0.0002 21.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCH61219.1 - 9.1e-07 28.2 4.4 9.5e-06 25.0 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCH61219.1 - 2.5e-06 26.8 5.4 4.3e-06 26.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCH61219.1 - 3.8e-05 23.2 2.3 0.00031 20.3 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 CCH61219.1 - 0.00041 19.9 2.2 0.0011 18.5 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CCH61219.1 - 0.00054 19.1 0.3 0.0011 18.1 0.2 1.5 1 0 0 1 1 1 1 SHNi-TPR TPR_14 PF13428.1 CCH61219.1 - 0.025 15.1 0.4 0.14 12.8 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Prog_receptor PF02161.10 CCH61219.1 - 7.5 5.2 7.7 12 4.5 5.4 1.4 1 0 0 1 1 1 0 Progesterone receptor 3Beta_HSD PF01073.14 CCH61220.1 - 1.2e-81 273.5 0.0 1.5e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCH61220.1 - 1.4e-29 103.1 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCH61220.1 - 1e-15 57.3 0.0 2.9e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CCH61220.1 - 1.1e-11 44.1 0.0 1.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CCH61220.1 - 3.2e-06 27.2 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCH61220.1 - 1.4e-05 24.1 0.0 0.0001 21.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCH61220.1 - 0.0096 15.8 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH61220.1 - 0.1 12.2 0.0 0.93 9.1 0.0 2.1 1 1 0 1 1 1 0 KR domain DUP PF00674.13 CCH61221.1 - 4.6e-19 68.3 0.3 8.9e-19 67.4 0.2 1.5 1 1 0 1 1 1 1 DUP family Prok_Ub PF14454.1 CCH61221.1 - 0.1 12.2 0.0 0.49 10.0 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic Ubiquitin PMI_typeI PF01238.16 CCH61222.1 - 1.4e-157 524.5 0.1 1.6e-157 524.3 0.1 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 CCH61222.1 - 2.5e-05 23.9 0.0 0.0074 15.9 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.6 CCH61222.1 - 0.0031 16.9 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 2 Cupin domain DUF3770 PF12603.3 CCH61222.1 - 0.0082 15.2 1.1 0.013 14.6 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) GN3L_Grn1 PF08701.6 CCH61224.1 - 1.1e-23 82.9 12.9 1.1e-23 82.9 8.9 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CCH61224.1 - 2.8e-20 72.4 1.2 6.8e-15 55.0 0.0 3.2 2 1 1 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH61224.1 - 2.9e-08 33.1 0.1 2.3e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCH61224.1 - 0.00021 20.7 0.0 0.073 12.5 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCH61224.1 - 0.0015 18.3 8.2 0.42 10.4 0.3 4.0 2 2 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCH61224.1 - 0.0021 17.2 0.2 0.0039 16.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 CCH61224.1 - 0.023 13.4 0.0 0.059 12.1 0.0 1.6 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 CCH61224.1 - 0.1 13.1 2.3 1.4 9.4 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein CAP_GLY PF01302.20 CCH61225.1 - 4.5e-14 51.9 0.2 8.1e-14 51.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 CCH61225.1 - 1.4e-11 43.6 44.3 6.9e-05 22.3 0.8 6.3 3 1 6 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH61225.1 - 2.1e-09 36.9 45.7 5.4e-06 26.0 4.4 4.9 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CCH61225.1 - 7.6e-06 25.2 31.6 0.42 10.8 0.1 9.1 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.1 CCH61225.1 - 2.2e-05 24.0 35.7 0.34 11.1 0.1 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_7 PF13504.1 CCH61225.1 - 5.9e-05 22.6 19.0 22 5.8 0.3 8.3 7 0 0 7 7 7 1 Leucine rich repeat PTPA PF03095.10 CCH61226.1 - 4.5e-107 357.6 0.0 5.9e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PEPCK_ATP PF01293.15 CCH61227.1 - 1.1e-216 719.7 0.0 1.4e-216 719.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CCH61227.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.7 CCH61229.1 - 1.5e-15 57.1 35.0 2.1e-15 56.6 16.4 16.4 4 4 7 12 12 12 4 TPR/MLP1/MLP2-like protein DAO PF01266.19 CCH61231.1 - 2.3e-48 164.9 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCH61231.1 - 1.5e-09 37.2 0.0 2.9e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CCH61231.1 - 2.9e-07 29.9 0.1 2.5e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCH61231.1 - 0.00016 21.6 0.1 0.0095 15.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCH61231.1 - 0.00034 19.1 0.2 0.00061 18.3 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 CCH61231.1 - 0.00038 19.4 0.5 0.0052 15.6 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 CCH61231.1 - 0.00042 19.4 0.2 0.079 12.0 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GMC_oxred_N PF00732.14 CCH61231.1 - 0.0072 15.5 0.3 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.14 CCH61231.1 - 0.013 14.6 0.0 2 7.4 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 CCH61231.1 - 0.014 15.3 0.3 0.041 13.9 0.1 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CCH61231.1 - 0.043 13.4 1.1 0.14 11.7 0.8 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CCH61231.1 - 0.06 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UCH PF00443.24 CCH61232.1 - 5e-60 202.8 0.5 5e-60 202.8 0.3 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH61232.1 - 2.2e-30 106.1 0.0 2.2e-30 106.1 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCH61232.1 - 0.00079 19.7 0.0 0.0025 18.1 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DUF3571 PF12095.3 CCH61232.1 - 0.083 13.1 0.3 0.46 10.7 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) Zn-ribbon_8 PF09723.5 CCH61232.1 - 3.5 7.6 5.8 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Zinc ribbon domain Myb_DNA-bind_6 PF13921.1 CCH61233.1 - 9.3e-27 92.9 3.5 7.9e-10 38.6 0.6 4.1 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCH61233.1 - 1.9e-26 91.8 6.5 2.6e-12 46.5 0.1 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CCH61233.1 - 0.64 9.9 3.8 38 4.2 2.6 2.8 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Coa1 PF08695.5 CCH61234.1 - 4.6e-38 129.3 0.0 5.9e-38 128.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SKG6 PF08693.5 CCH61235.1 - 8.4e-05 21.8 0.1 0.00018 20.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain FH2 PF02181.18 CCH61236.1 - 8.3e-66 222.3 8.3 8.3e-66 222.3 5.7 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF1515 PF07439.6 CCH61236.1 - 0.87 9.4 7.9 0.15 11.9 1.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) DUF1664 PF07889.7 CCH61236.1 - 6.7 6.5 16.7 0.81 9.4 2.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Thiolase_N PF00108.18 CCH61237.1 - 9.9e-85 283.7 0.0 1.3e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCH61237.1 - 1.5e-49 166.5 0.3 3.2e-49 165.4 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCH61237.1 - 0.0033 16.9 1.2 0.005 16.3 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MIP-T3 PF10243.4 CCH61238.1 - 0.13 10.7 23.2 0.14 10.6 16.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1460 PF07313.7 CCH61239.1 - 0.0032 16.6 3.4 0.0085 15.3 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1460) vATP-synt_E PF01991.13 CCH61240.1 - 3e-57 193.0 16.0 3.5e-57 192.8 11.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 CCH61240.1 - 1.5 7.8 12.2 0.4 9.7 6.5 1.4 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M CorA PF01544.13 CCH61241.1 - 0.00011 21.3 10.7 0.00037 19.6 7.4 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein RNase_P_Rpp14 PF01900.14 CCH61243.1 - 1.4e-31 108.5 0.2 1.7e-31 108.3 0.2 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RRM_4 PF10598.4 CCH61243.1 - 0.032 14.0 0.4 0.06 13.2 0.3 1.4 1 0 0 1 1 1 0 RNA recognition motif of the spliceosomal PrP8 Fungal_trans PF04082.13 CCH61244.1 - 9e-35 119.7 3.8 1.9e-34 118.7 2.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH61244.1 - 3.4e-07 30.0 11.3 5.5e-07 29.3 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.12 CCH61245.1 - 2.7e-12 46.6 0.1 8.6e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain DTHCT PF08070.6 CCH61245.1 - 0.12 13.0 5.6 0.43 11.2 4.0 1.9 1 1 0 1 1 1 0 DTHCT (NUC029) region Mis12 PF05859.7 CCH61246.1 - 2.4e-31 108.4 0.8 2.4e-31 108.4 0.6 2.0 1 1 1 2 2 2 1 Mis12 protein DUF3993 PF13158.1 CCH61246.1 - 0.025 14.4 0.2 0.061 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) RNA_pol_Rpb1_5 PF04998.12 CCH61247.1 - 1.9e-98 329.1 2.2 1e-97 326.7 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCH61247.1 - 2.4e-63 213.0 1.8 3.3e-63 212.5 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCH61247.1 - 1.6e-39 135.1 0.3 5.7e-38 130.1 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCH61247.1 - 8.6e-24 83.3 2.9 2.5e-23 81.8 0.0 3.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 CCH61247.1 - 8.6e-20 71.2 7.8 8.6e-20 71.2 5.4 4.1 3 2 0 3 3 3 1 RNA polymerase Rpb1, domain 1 PFK PF00365.15 CCH61247.1 - 0.07 12.0 0.1 0.23 10.3 0.2 1.8 2 0 0 2 2 2 0 Phosphofructokinase GTP_EFTU PF00009.22 CCH61248.1 - 8.9e-32 110.0 0.0 8.9e-32 110.0 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCH61248.1 - 2.1e-20 72.6 0.0 5.8e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCH61248.1 - 4.8e-16 58.6 1.2 1.1e-09 38.2 0.0 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH61248.1 - 7.7e-07 29.0 0.1 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CCH61248.1 - 0.0071 16.8 0.0 0.0071 16.8 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein TGS PF02824.16 CCH61249.1 - 5.2e-21 74.2 0.1 9.7e-21 73.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCH61249.1 - 1.6e-16 60.3 0.0 3.1e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH61249.1 - 5.5e-09 35.4 0.1 1.3e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCH61249.1 - 0.0025 17.6 0.4 1.6 8.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CCH61249.1 - 0.0059 15.4 0.1 0.012 14.4 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 CCH61249.1 - 0.013 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 CCH61249.1 - 0.063 12.5 0.2 2 7.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Sugar_tr PF00083.19 CCH61250.1 - 1.1e-156 522.0 39.7 1.2e-156 521.7 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH61250.1 - 5.3e-33 114.1 38.9 3e-31 108.4 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH61250.1 - 0.00024 19.4 4.7 0.00041 18.6 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cytochrom_B_N PF00033.14 CCH61250.1 - 0.004 16.5 1.9 0.004 16.5 1.3 3.1 4 0 0 4 4 4 1 Cytochrome b(N-terminal)/b6/petB ATP1G1_PLM_MAT8 PF02038.11 CCH61250.1 - 0.05 12.6 0.8 0.21 10.6 0.5 2.1 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family PRP21_like_P PF12230.3 CCH61251.1 - 5.8e-26 91.4 9.1 5.8e-26 91.4 6.3 1.5 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CCH61251.1 - 0.017 14.7 0.2 0.046 13.3 0.1 1.8 1 0 0 1 1 1 0 Surp module DUF2407_C PF13373.1 CCH61251.1 - 0.52 10.2 3.4 0.23 11.3 0.4 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Pro_isomerase PF00160.16 CCH61252.1 - 6.7e-43 146.5 0.0 1.1e-42 145.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCH61252.1 - 1.6e-10 40.4 1.1 2.2e-06 27.1 0.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCH61252.1 - 1e-09 37.5 5.0 3e-09 36.0 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61252.1 - 2.4e-08 33.2 2.6 1.7e-07 30.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCH61252.1 - 5.5e-06 26.2 0.9 4.1e-05 23.4 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCH61252.1 - 0.00065 20.1 0.2 0.012 16.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCH61252.1 - 0.00087 18.9 0.0 0.0032 17.1 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCH61252.1 - 0.0011 19.2 2.0 0.0029 17.9 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCH61252.1 - 0.0016 18.5 0.1 0.19 11.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCH61252.1 - 0.0036 17.9 0.2 0.091 13.4 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCH61252.1 - 0.013 14.5 0.2 0.023 13.7 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCH61252.1 - 0.037 13.8 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCH61252.1 - 0.13 12.6 0.7 2 8.8 0.0 2.7 1 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCH61252.1 - 0.38 10.9 3.8 1.5 9.0 0.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CDP-OH_P_transf PF01066.16 CCH61253.1 - 2.2e-18 66.4 1.3 3.4e-18 65.7 0.9 1.5 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Tubulin PF00091.20 CCH61254.1 - 5.3e-69 232.3 0.1 1e-68 231.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCH61254.1 - 1.2e-09 38.2 5.2 1.7e-09 37.7 1.2 2.7 2 1 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCH61254.1 - 2.6e-05 24.2 0.1 6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCH61254.1 - 0.00079 18.9 0.0 0.0089 15.5 0.0 2.3 2 0 0 2 2 2 1 Tubulin domain DUF2013 PF09431.5 CCH61255.1 - 5.6e-43 146.0 14.7 5.6e-43 146.0 10.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Sel1 PF08238.7 CCH61256.1 - 8.2e-16 58.0 18.4 5.2e-06 26.9 0.6 9.2 10 0 0 10 10 10 2 Sel1 repeat TPR_1 PF00515.23 CCH61256.1 - 3.7e-07 29.4 5.7 0.45 10.2 0.1 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61256.1 - 6.3e-05 22.5 2.0 1 9.4 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCH61256.1 - 0.00011 21.7 10.6 1.2 9.1 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCH61256.1 - 0.00053 19.5 1.6 3.2 7.7 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCH61256.1 - 0.00057 19.4 11.5 0.0012 18.4 0.7 4.4 4 1 1 5 5 5 2 TPR repeat Apc3 PF12895.2 CCH61256.1 - 0.18 11.9 7.4 0.93 9.6 0.3 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 ENTH PF01417.15 CCH61257.1 - 1.9e-35 121.4 0.0 4.2e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 ENTH domain DNA_ligase_A_M PF01068.16 CCH61258.1 - 5.5e-59 198.9 0.0 9.2e-59 198.2 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCH61258.1 - 3.3e-53 180.1 0.2 7.2e-53 179.0 0.1 1.6 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCH61258.1 - 8.5e-25 86.9 0.2 3.3e-24 85.1 0.0 2.1 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CCH61258.1 - 0.012 15.2 0.5 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain zf-RanBP PF00641.13 CCH61259.1 - 9.8e-22 75.7 10.9 1.8e-10 39.7 0.7 3.1 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CCH61259.1 - 5.9e-07 29.0 0.0 0.00037 20.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH61259.1 - 0.0071 16.3 0.0 0.04 13.8 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 CCH61259.1 - 0.12 12.2 8.6 1.1 9.1 1.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon POC1 PF10450.4 CCH61260.1 - 3.8e-63 212.8 5.0 7.2e-45 152.8 0.7 2.0 1 1 1 2 2 2 2 POC1 chaperone Nop PF01798.13 CCH61261.1 - 3.2e-60 201.7 0.1 6.9e-60 200.6 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCH61261.1 - 5.9e-27 93.2 0.3 1.9e-26 91.6 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCH61261.1 - 2e-23 82.3 1.0 2e-23 82.3 0.7 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 CCH61261.1 - 0.72 9.7 23.6 1.1 9.1 16.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PPP4R2 PF09184.6 CCH61261.1 - 2.2 7.7 29.3 2.8 7.4 19.6 1.6 2 0 0 2 2 2 0 PPP4R2 RR_TM4-6 PF06459.7 CCH61261.1 - 4 7.2 32.2 6.2 6.6 22.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC48_N PF02359.13 CCH61262.1 - 0.068 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain HATPase_c PF02518.21 CCH61263.1 - 1.4e-25 89.1 0.5 1.4e-24 85.9 0.4 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCH61263.1 - 2.6e-25 88.5 0.5 5.3e-25 87.6 0.4 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCH61263.1 - 4.1e-10 39.5 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 CCH61263.1 - 0.0012 18.9 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 HAMP domain ubiquitin PF00240.18 CCH61264.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCH61264.1 - 3.7e-31 106.4 11.3 5.9e-31 105.8 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCH61264.1 - 4e-20 71.2 0.7 6.5e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCH61264.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCH61264.1 - 0.0001 22.0 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCH61264.1 - 0.0055 16.5 0.1 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCH61264.1 - 0.012 15.7 0.1 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CCH61264.1 - 0.12 12.1 1.5 0.54 10.1 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2870 PF11069.3 CCH61264.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) EMP24_GP25L PF01105.19 CCH61265.1 - 8.4e-32 110.3 0.3 1e-31 110.0 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4298 PF14131.1 CCH61265.1 - 0.038 13.8 0.2 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) DUF4199 PF13858.1 CCH61265.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) FUN14 PF04930.10 CCH61266.1 - 0.00013 22.2 2.9 0.00015 21.9 1.2 1.8 2 1 0 2 2 2 1 FUN14 family DUF3139 PF11337.3 CCH61266.1 - 0.3 11.4 2.4 11 6.3 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3139) B56 PF01603.15 CCH61267.1 - 1.4e-133 445.4 26.8 1.5e-127 425.6 14.3 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Spo7 PF03907.8 CCH61268.1 - 4.2e-64 215.9 7.0 5e-64 215.7 4.9 1.0 1 0 0 1 1 1 1 Spo7-like protein DUF2208 PF09973.4 CCH61268.1 - 0.0001 21.6 0.8 0.0002 20.7 0.2 1.6 1 1 0 2 2 2 1 Predicted membrane protein (DUF2208) DUF1132 PF06575.7 CCH61268.1 - 0.11 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) DUF3722 PF12519.3 CCH61269.1 - 3e-20 72.5 2.1 3e-20 72.5 1.5 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3722) SAP30_Sin3_bdg PF13867.1 CCH61269.1 - 0.086 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF775 PF05603.7 CCH61270.1 - 1.2e-55 188.1 0.1 1.5e-55 187.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA-synt_1c PF00749.16 CCH61271.1 - 6.7e-108 360.0 0.0 8.5e-108 359.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.14 CCH61272.1 - 3.5e-15 55.8 37.1 2.2e-14 53.2 25.7 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCH61272.1 - 2.9e-10 40.8 102.5 9.9e-07 29.2 36.5 5.3 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CCH61272.1 - 6e-06 25.6 0.0 1.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH61272.1 - 1.4e-05 25.2 0.3 1.4e-05 25.2 0.2 5.1 1 1 2 4 4 4 1 AAA domain FtsK_SpoIIIE PF01580.13 CCH61272.1 - 0.011 15.2 3.9 0.65 9.4 0.0 3.3 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 CCH61272.1 - 0.017 14.5 0.0 0.047 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCH61272.1 - 0.048 13.5 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCH61272.1 - 0.069 13.4 0.0 0.069 13.4 0.0 4.7 3 2 0 3 3 3 0 ABC transporter AAA_17 PF13207.1 CCH61272.1 - 2.5 8.9 8.0 6.4 7.6 1.9 3.8 2 1 0 2 2 2 0 AAA domain SKIP_SNW PF02731.10 CCH61274.1 - 2.9e-42 143.8 9.9 6.3e-42 142.7 6.9 1.5 1 0 0 1 1 1 1 SKIP/SNW domain IFT20 PF14931.1 CCH61274.1 - 0.039 13.8 8.7 0.16 11.9 6.0 2.1 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 SNARE PF05739.14 CCH61275.1 - 1.3e-08 34.3 3.3 1.4e-08 34.2 0.2 2.7 3 0 0 3 3 3 1 SNARE domain Use1 PF09753.4 CCH61275.1 - 0.0099 15.3 2.9 0.017 14.5 2.0 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Sds3 PF08598.6 CCH61276.1 - 1.3e-37 129.3 0.0 1.3e-37 129.3 0.0 2.1 2 1 0 2 2 2 1 Sds3-like Cys_Met_Meta_PP PF01053.15 CCH61277.1 - 2.2e-145 483.7 0.0 2.5e-145 483.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CCH61277.1 - 2.5e-06 26.0 0.0 3.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CCH61277.1 - 0.008 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 CCH61277.1 - 0.028 13.1 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF805 PF05656.9 CCH61278.1 - 0.096 12.5 2.5 0.14 11.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Claudin_2 PF13903.1 CCH61278.1 - 0.67 9.6 5.4 2.9 7.5 0.3 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Exo_endo_phos PF03372.18 CCH61279.1 - 1.7e-13 51.0 0.1 2.1e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HEAT PF02985.17 CCH61280.1 - 7.4e-35 115.8 16.8 0.016 15.2 0.0 12.4 12 0 0 12 12 12 9 HEAT repeat HEAT_2 PF13646.1 CCH61280.1 - 1.1e-28 99.3 1.8 3e-06 27.4 0.0 7.0 3 1 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 CCH61280.1 - 1.2e-11 44.7 6.1 0.018 15.3 0.0 7.0 4 1 4 8 8 8 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCH61280.1 - 8.9e-10 38.7 7.2 3.6 8.1 0.1 9.0 9 1 1 10 10 10 1 HEAT-like repeat Ipi1_N PF12333.3 CCH61280.1 - 0.035 14.0 0.7 0.56 10.2 0.0 3.2 2 1 1 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 CCH61280.1 - 0.58 10.0 4.2 18 5.3 0.0 4.6 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat Pkinase PF00069.20 CCH61282.1 - 5.7e-62 209.2 0.0 1.1e-61 208.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61282.1 - 4.7e-22 78.2 0.0 7.5e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61282.1 - 1.3e-06 27.5 0.0 2.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH61282.1 - 0.0015 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCH61282.1 - 0.0037 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_8 PF13188.1 CCH61282.1 - 0.093 12.6 0.0 0.65 9.9 0.0 2.3 2 0 0 2 2 2 0 PAS domain PAS PF00989.19 CCH61282.1 - 0.12 12.1 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 PAS fold Med15_fungi PF05397.7 CCH61284.1 - 2.5e-38 130.5 7.2 2.5e-38 130.5 5.0 7.3 6 1 0 6 6 6 1 Mediator complex subunit 15 PMT PF02366.13 CCH61285.1 - 1.9e-78 263.2 18.7 1.9e-78 263.2 13.0 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCH61285.1 - 1.4e-22 80.2 1.2 2.6e-22 79.3 0.8 1.5 1 1 0 1 1 1 1 MIR domain WHIM2 PF15613.1 CCH61285.1 - 0.012 15.5 0.6 0.04 13.8 0.0 2.2 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 2 LDB19 PF13002.2 CCH61286.1 - 2.6e-63 213.0 0.1 3.8e-63 212.4 0.1 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 CCH61286.1 - 0.00041 20.1 0.5 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RasGEF PF00617.14 CCH61287.1 - 3.6e-42 144.2 4.1 3.6e-42 144.2 2.8 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCH61287.1 - 7.4e-15 54.9 3.3 7.4e-15 54.9 2.3 4.6 4 0 0 4 4 4 1 RasGEF N-terminal motif Ribosomal_L28e PF01778.12 CCH61288.1 - 1.6e-34 118.8 2.9 1.6e-34 118.8 2.0 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CCH61288.1 - 3.3e-32 110.5 19.2 3.3e-32 110.5 13.3 2.9 3 1 0 3 3 3 1 Mak16 protein C-terminal region Nop14 PF04147.7 CCH61288.1 - 0.092 10.6 26.3 0.11 10.3 18.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 CCH61288.1 - 1.1 7.8 21.7 1.5 7.4 15.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UBN2 PF14223.1 CCH61290.1 - 0.0097 15.6 0.0 0.013 15.2 0.0 1.3 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Cypo_polyhedrin PF05865.6 CCH61290.1 - 0.013 14.7 0.0 0.017 14.3 0.0 1.2 1 1 0 1 1 1 0 Cypovirus polyhedrin protein YqzH PF14164.1 CCH61290.1 - 0.12 12.2 0.7 5.7 6.9 0.1 2.3 2 0 0 2 2 2 0 YqzH-like protein rve PF00665.21 CCH61291.1 - 0.00022 21.3 0.0 0.00035 20.6 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Rapamycin_bind PF08771.6 CCH61292.1 - 0.061 13.4 0.3 1.4 9.0 0.1 2.1 1 1 1 2 2 2 0 Rapamycin binding domain Aldedh PF00171.17 CCH61293.1 - 1.4e-13 50.0 1.0 1.4e-08 33.5 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Saw1 PF11561.3 CCH61294.1 - 1.7e-48 164.8 9.9 2e-48 164.6 6.9 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Myosin_head PF00063.16 CCH61296.1 - 3.5e-257 854.9 14.6 3.5e-257 854.9 10.1 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CCH61296.1 - 2.8e-33 113.9 2.9 2.8e-33 113.9 2.0 2.9 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 CCH61296.1 - 1.2e-10 40.0 19.9 5.8e-05 22.3 0.2 6.3 6 0 0 6 6 6 4 IQ calmodulin-binding motif AAA_22 PF13401.1 CCH61296.1 - 0.0039 17.3 0.0 0.0039 17.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain Myosin_N PF02736.14 CCH61296.1 - 0.012 15.2 0.1 0.028 14.0 0.0 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ABC_tran PF00005.22 CCH61296.1 - 0.095 12.9 0.0 0.095 12.9 0.0 3.4 3 1 0 3 3 3 0 ABC transporter AAA_19 PF13245.1 CCH61296.1 - 0.18 11.5 0.0 0.47 10.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Synaptobrevin PF00957.16 CCH61297.1 - 6.4e-32 109.0 2.0 7.2e-32 108.8 1.4 1.0 1 0 0 1 1 1 1 Synaptobrevin PRT_C PF08372.5 CCH61297.1 - 0.07 12.6 0.1 0.087 12.3 0.1 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal ODV-E18 PF10717.4 CCH61297.1 - 0.093 12.1 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Phospholamban PF04272.9 CCH61297.1 - 0.1 12.0 1.3 0.16 11.4 0.9 1.3 1 0 0 1 1 1 0 Phospholamban DUF912 PF06024.7 CCH61297.1 - 0.22 11.6 1.3 0.25 11.4 0.9 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DNA_pol_A PF00476.15 CCH61299.1 - 6.7e-97 324.5 0.0 3.2e-96 322.2 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase family A Pkinase PF00069.20 CCH61300.1 - 1.9e-49 168.1 5.6 2.9e-48 164.3 3.9 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61300.1 - 2.9e-16 59.3 1.1 4.8e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCH61300.1 - 0.00011 22.0 0.0 0.00042 20.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCH61300.1 - 0.015 14.8 0.4 0.048 13.2 0.3 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase bZIP_1 PF00170.16 CCH61301.1 - 1e-08 35.0 7.0 1.8e-08 34.2 4.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCH61301.1 - 9.4e-07 28.5 8.4 1.8e-06 27.6 5.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper HeLo PF14479.1 CCH61301.1 - 0.01 15.5 0.3 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation Metallophos PF00149.23 CCH61302.1 - 2.6e-22 79.2 5.0 2.6e-22 79.2 3.5 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DnaJ-X PF14308.1 CCH61303.1 - 1.2e-53 181.4 8.7 1.2e-53 181.4 6.0 2.2 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCH61303.1 - 1.3e-25 88.8 1.7 3.9e-25 87.3 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain Tom37_C PF11801.3 CCH61303.1 - 0.066 13.0 0.7 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 Tom37 C-terminal domain Lipoprotein_6 PF01441.14 CCH61303.1 - 0.13 12.0 4.3 0.21 11.4 0.3 2.3 2 0 0 2 2 2 0 Lipoprotein HeLo PF14479.1 CCH61303.1 - 4.7 6.9 8.8 7.4 6.2 4.8 2.2 2 1 0 2 2 2 0 Prion-inhibition and propagation MFS_1 PF07690.11 CCH61304.1 - 3.6e-28 98.2 42.7 3.6e-28 98.2 29.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH61304.1 - 5.6e-05 21.5 6.1 8.8e-05 20.8 4.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SGL PF08450.7 CCH61305.1 - 1.1e-48 165.8 0.0 1.3e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 CCH61305.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Arylesterase MFS_1 PF07690.11 CCH61306.1 - 7.5e-37 126.8 33.0 7.5e-37 126.8 22.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCH61306.1 - 5.2e-06 24.9 2.8 1e-05 23.9 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 CCH61306.1 - 0.24 11.8 0.3 0.91 9.9 0.2 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_A2B PF12384.3 CCH61308.1 - 3.2e-12 46.1 0.0 5.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase RVT_1 PF00078.22 CCH61308.1 - 1.9e-11 43.7 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 CCH61308.1 - 1.2e-06 28.5 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CCH61308.1 - 0.00014 22.3 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCH61308.1 - 0.0024 17.6 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Retrotrans_gag PF03732.12 CCH61309.1 - 1.7e-13 50.3 0.0 2.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1825 PF08855.5 CCH61309.1 - 0.053 13.5 0.1 2 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) CYSTM PF12734.2 CCH61310.1 - 1.9e-07 31.0 40.5 0.00017 21.5 28.1 3.1 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance DAHP_synth_1 PF00793.15 CCH61311.1 - 2e-100 334.9 0.0 2.4e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Gon7 PF08738.5 CCH61312.1 - 0.14 12.1 8.4 3.2 7.7 0.8 3.2 2 1 0 2 2 2 0 Gon7 family HALZ PF02183.13 CCH61312.1 - 0.23 11.1 14.6 0.67 9.7 1.0 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Iron_permease PF04120.7 CCH61312.1 - 1.4 8.4 6.0 12 5.5 0.9 2.5 2 0 0 2 2 2 0 Low affinity iron permease UCH PF00443.24 CCH61313.1 - 3e-45 154.4 0.0 1.2e-44 152.4 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH61313.1 - 5.3e-23 81.8 0.0 1.9e-22 80.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCH61313.1 - 8.1e-22 77.1 5.1 8.1e-22 77.1 3.5 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CCH61313.1 - 1e-15 56.9 0.1 6.1e-08 32.2 0.2 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ECH PF00378.15 CCH61314.1 - 1.1e-26 93.5 0.0 2.5e-26 92.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CCH61314.1 - 1e-17 64.3 0.6 3.8e-17 62.5 0.1 2.2 2 1 1 3 3 3 1 2-enoyl-CoA Hydratase C-terminal region SeleniumBinding PF11524.3 CCH61314.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Selenium binding protein Pkinase PF00069.20 CCH61315.1 - 6e-37 127.2 0.0 1e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61315.1 - 1.4e-24 86.6 0.0 2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61315.1 - 0.0017 17.3 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CaM-KIIN PF15170.1 CCH61315.1 - 0.0054 16.6 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 Calcium/calmodulin-dependent protein kinase II inhibitor APH PF01636.18 CCH61315.1 - 0.01 15.5 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCH61315.1 - 0.065 12.2 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ORC2 PF04084.9 CCH61316.1 - 4.8e-105 351.0 2.3 6.4e-105 350.5 1.6 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 tRNA-synt_2 PF00152.15 CCH61317.1 - 1.1e-87 293.9 0.8 1.1e-87 293.9 0.6 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCH61317.1 - 4.4e-13 48.8 0.3 4.4e-12 45.6 0.2 2.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCH61317.1 - 9.8e-08 31.4 0.0 0.0013 17.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) E1-E2_ATPase PF00122.15 CCH61318.1 - 1.6e-63 213.8 6.0 1.6e-63 213.8 4.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCH61318.1 - 2.2e-35 121.8 1.0 2.2e-35 121.8 0.7 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCH61318.1 - 5.5e-27 95.5 0.0 6.1e-22 79.1 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH61318.1 - 2.9e-15 56.9 0.0 7.7e-15 55.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH61318.1 - 6.2e-15 54.9 2.9 2.4e-14 53.0 2.0 2.0 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCH61318.1 - 4.4e-14 51.6 1.2 5.8e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCH61318.1 - 0.0015 18.1 0.6 0.0015 18.1 0.4 3.6 3 1 2 5 5 5 1 haloacid dehalogenase-like hydrolase Asp PF00026.18 CCH61319.1 - 1.8e-68 231.1 14.1 4.8e-58 196.8 4.5 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH61319.1 - 1.1e-08 35.2 1.5 0.0034 17.3 0.3 2.7 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal PAPS_reduct PF01507.14 CCH61322.1 - 6.6e-34 117.2 0.0 4.4e-33 114.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sdh5 PF03937.11 CCH61323.1 - 2e-25 88.2 0.5 3.1e-25 87.6 0.3 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase AlgF PF11182.3 CCH61324.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF RE_HindIII PF09518.5 CCH61324.1 - 0.051 12.4 0.6 0.07 12.0 0.4 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease DUF2470 PF10615.4 CCH61324.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) PRP3 PF08572.5 CCH61325.1 - 6.1e-57 192.5 17.7 7.9e-57 192.1 12.2 1.1 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CCH61325.1 - 1.8e-30 105.2 0.1 1.8e-30 105.2 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) TRAPP PF04051.11 CCH61327.1 - 3.8e-43 146.6 0.0 4.9e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Baculo_E66 PF04850.7 CCH61327.1 - 0.0029 16.6 0.2 0.0039 16.2 0.1 1.1 1 0 0 1 1 1 1 Baculovirus E66 occlusion-derived virus envelope protein Phage-Gp8 PF09215.5 CCH61327.1 - 0.026 13.6 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage T4, Gp8 DUF1180 PF06679.7 CCH61327.1 - 0.041 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Acetyltransf_1 PF00583.19 CCH61328.1 - 9.6e-16 57.5 0.0 1.4e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCH61328.1 - 4.9e-06 26.2 0.0 8.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCH61328.1 - 3.3e-05 23.9 0.1 7.9e-05 22.7 0.1 1.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCH61328.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCH61328.1 - 0.011 15.5 0.3 0.021 14.7 0.2 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCH61328.1 - 0.022 14.9 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Metallophos_2 PF12850.2 CCH61329.1 - 1.5e-14 54.1 0.0 3.1e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Autophagy_Cterm PF10381.4 CCH61329.1 - 0.018 14.1 0.4 0.034 13.2 0.3 1.4 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal Brr6_like_C_C PF10104.4 CCH61329.1 - 0.5 9.8 1.8 1.1 8.8 1.2 1.6 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain tRNA-synt_2b PF00587.20 CCH61330.1 - 5.1e-24 84.7 0.0 9.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCH61330.1 - 9.6e-05 22.3 7.3 0.00026 20.9 5.0 1.8 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Reo_sigmaC PF04582.7 CCH61330.1 - 0.15 11.1 0.8 0.24 10.5 0.5 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CCH61330.1 - 0.27 11.0 5.6 1.5 8.6 0.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 CCH61330.1 - 0.28 10.9 8.0 0.55 10.0 5.5 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.6 CCH61330.1 - 0.31 11.4 5.0 1.1 9.6 3.4 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF342 PF03961.8 CCH61330.1 - 2.5 6.4 8.9 1.6 7.0 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Ribosomal_L27e PF01777.13 CCH61331.1 - 6.1e-36 122.4 6.6 8.3e-36 121.9 4.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCH61331.1 - 0.00027 20.5 1.5 0.0005 19.6 1.0 1.5 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 CCH61331.1 - 0.1 11.3 0.2 0.16 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Mito_carr PF00153.22 CCH61332.1 - 9.2e-09 34.8 0.0 0.025 14.2 0.0 3.7 4 1 0 4 4 4 3 Mitochondrial carrier protein Dpy-30 PF05186.8 CCH61333.1 - 2.3e-11 42.9 0.1 3.4e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif DAO PF01266.19 CCH61334.1 - 2.8e-59 200.8 0.0 1.3e-38 132.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCH61334.1 - 1.1e-05 25.3 0.0 3.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Cache_1 PF02743.13 CCH61334.1 - 0.013 15.0 0.2 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 Cache domain Thi4 PF01946.12 CCH61334.1 - 0.041 12.9 0.4 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 CCH61334.1 - 0.053 13.2 0.3 0.7 9.6 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Saccharop_dh PF03435.13 CCH61334.1 - 0.066 12.1 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pkinase PF00069.20 CCH61335.1 - 8.5e-65 218.4 0.0 1.6e-64 217.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61335.1 - 7.5e-31 107.1 0.0 1.1e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61335.1 - 6.1e-07 28.6 0.0 1.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH61335.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.13 CCH61336.1 - 8.7e-28 96.2 1.2 1.5e-27 95.5 0.8 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCH61336.1 - 1e-20 73.7 0.5 4.2e-20 71.7 0.4 2.0 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain p450 PF00067.17 CCH61337.1 - 4.3e-107 358.4 0.0 5e-107 358.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.21 CCH61338.1 - 4.9e-05 23.4 3.2 4.9e-05 23.4 2.2 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCH61338.1 - 0.0036 17.5 0.6 0.0036 17.5 0.4 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCH61338.1 - 0.0089 16.3 1.4 0.0089 16.3 1.0 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger DUF1971 PF09313.6 CCH61338.1 - 0.092 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) HNH PF01844.18 CCH61338.1 - 0.1 12.5 2.2 3.3 7.6 0.1 2.6 2 0 0 2 2 2 0 HNH endonuclease zf-Di19 PF05605.7 CCH61338.1 - 0.74 9.9 6.2 0.38 10.9 2.5 2.0 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CCH61338.1 - 1.2 9.3 11.5 4.1 7.6 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-DHHC PF01529.15 CCH61339.1 - 2e-29 102.1 3.0 2e-29 102.1 2.1 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase MARVEL PF01284.18 CCH61339.1 - 1.3 8.8 7.4 0.088 12.6 1.2 1.9 2 0 0 2 2 2 0 Membrane-associating domain A_deaminase PF00962.17 CCH61340.1 - 3.6e-119 397.5 0.0 4.9e-119 397.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MSC PF09402.5 CCH61341.1 - 3.4e-47 160.7 2.0 3.4e-47 160.7 1.4 3.6 4 0 0 4 4 4 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCH61341.1 - 3.5e-08 32.8 1.0 1.1e-07 31.2 0.7 1.9 1 0 0 1 1 1 1 HeH/LEM domain Endonuc-dimeris PF09124.5 CCH61341.1 - 0.00068 19.2 0.3 0.00068 19.2 0.2 2.2 2 0 0 2 2 2 1 T4 recombination endonuclease VII, dimerisation YicC_N PF03755.8 CCH61341.1 - 0.033 14.1 0.3 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 YicC-like family, N-terminal region HECT PF00632.20 CCH61342.1 - 1.3e-89 300.5 0.2 1.3e-89 300.5 0.1 2.5 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 CCH61342.1 - 2.1e-77 260.6 12.2 7.7e-77 258.7 8.4 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CCH61342.1 - 1.3e-42 145.9 2.3 1.3e-42 145.9 1.6 3.0 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 CCH61342.1 - 7.4e-15 54.8 1.9 7.4e-15 54.8 1.3 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) Ndc1_Nup PF09531.5 CCH61343.1 - 2.2e-23 82.5 40.4 1.8e-15 56.4 0.2 3.6 1 1 2 3 3 3 3 Nucleoporin protein Ndc1-Nup Na_H_Exchanger PF00999.16 CCH61344.1 - 1.7e-65 221.0 34.0 2.2e-65 220.6 23.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MtrF PF09472.5 CCH61344.1 - 0.079 12.2 1.4 11 5.4 0.0 2.9 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Guanylate_kin PF00625.16 CCH61345.1 - 1e-69 233.6 0.0 1.1e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CCH61345.1 - 1.1e-07 31.7 0.0 2.4e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH61345.1 - 4.8e-06 26.7 0.1 0.00011 22.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH61345.1 - 3.5e-05 24.6 0.0 6.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH61345.1 - 4.1e-05 23.6 0.0 0.00014 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CCH61345.1 - 5.4e-05 23.5 0.0 0.00014 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCH61345.1 - 0.00048 20.0 0.0 0.001 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCH61345.1 - 0.00069 19.9 0.0 0.00081 19.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA PF00004.24 CCH61345.1 - 0.00099 19.3 0.1 0.0022 18.2 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CCH61345.1 - 0.001 19.5 0.0 0.0033 17.9 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CCH61345.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 CCH61345.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCH61345.1 - 0.0022 18.1 0.0 0.0038 17.3 0.0 1.7 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 CCH61345.1 - 0.0022 17.9 0.1 0.0052 16.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CCH61345.1 - 0.0032 17.1 0.0 0.012 15.2 0.0 2.0 2 1 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 CCH61345.1 - 0.0032 16.9 1.4 0.013 14.9 0.1 2.3 2 1 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 CCH61345.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 CCH61345.1 - 0.0082 15.7 1.2 0.071 12.6 0.9 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCH61345.1 - 0.0084 15.8 0.4 0.025 14.2 0.3 1.9 1 1 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 CCH61345.1 - 0.0086 15.0 0.1 0.046 12.6 0.0 1.9 1 1 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 CCH61345.1 - 0.026 14.2 0.1 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_10 PF12846.2 CCH61345.1 - 0.029 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 CCH61345.1 - 0.029 14.6 2.2 0.091 13.0 1.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCH61345.1 - 0.031 14.0 0.1 0.097 12.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 CCH61345.1 - 0.04 12.9 0.0 0.065 12.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 CCH61345.1 - 0.05 13.0 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CCH61345.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCH61345.1 - 0.082 12.3 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CCH61345.1 - 0.09 12.7 0.6 0.19 11.6 0.2 1.6 1 1 0 2 2 2 0 AAA domain ubiquitin PF00240.18 CCH61346.1 - 0.0041 16.4 0.3 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 CCH61346.1 - 0.017 15.2 1.0 0.15 12.2 0.2 2.8 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Lamp PF01299.12 CCH61346.1 - 1.3 8.1 8.0 2.5 7.1 5.5 1.4 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) AhpC-TSA PF00578.16 CCH61347.1 - 7.5e-36 122.5 0.0 3.3e-35 120.4 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCH61347.1 - 1.1e-17 63.9 0.0 1.8e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CCH61347.1 - 2.6e-10 39.7 0.2 4.6e-10 38.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PIG-P PF08510.7 CCH61348.1 - 1.5 8.4 6.9 8.3 6.0 4.8 2.3 1 1 0 1 1 1 0 PIG-P Metallophos PF00149.23 CCH61349.1 - 8.2e-11 41.6 2.3 1.9e-10 40.4 1.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SPT16 PF08644.6 CCH61349.1 - 0.88 9.3 7.3 2.3 8.0 0.2 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Homeobox PF00046.24 CCH61350.1 - 4.3e-17 61.4 4.7 9.7e-17 60.3 3.3 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCH61350.1 - 0.008 15.8 0.6 0.028 14.1 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain Ribosomal_L4 PF00573.17 CCH61351.1 - 3.4e-35 121.1 0.7 1.8e-32 112.3 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein L4/L1 family U3_assoc_6 PF08640.6 CCH61352.1 - 4.6e-31 106.4 3.2 4.6e-31 106.4 2.2 3.2 3 1 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 CCH61352.1 - 0.00011 21.2 6.8 0.073 11.9 0.3 2.9 1 1 0 2 2 2 2 NRDE-2, necessary for RNA interference CARD PF00619.16 CCH61352.1 - 0.047 13.5 0.1 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Caspase recruitment domain ZZ PF00569.12 CCH61353.1 - 9e-17 60.3 8.2 1.5e-16 59.6 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCH61353.1 - 1.3e-07 31.5 0.0 3.2e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH61353.1 - 0.0015 18.6 1.6 0.017 15.1 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF676 PF05057.9 CCH61354.1 - 7.6e-47 159.4 0.0 1.1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CCH61354.1 - 1.3e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 CCH61354.1 - 0.0072 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1353 PF07087.6 CCH61354.1 - 0.043 13.2 0.0 8.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Med13_C PF06333.7 CCH61355.1 - 1.4e-78 264.3 3.7 1.5e-51 175.2 1.1 3.7 3 2 1 4 4 4 2 Mediator complex subunit 13 C-terminal Pribosyltran PF00156.22 CCH61356.1 - 3e-20 72.1 0.0 4.5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCH61356.1 - 0.0031 16.7 0.0 0.0045 16.2 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DOT1 PF08123.8 CCH61357.1 - 5.2e-79 264.3 0.0 1.1e-78 263.3 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CCH61357.1 - 0.00069 20.1 0.1 0.0029 18.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH61357.1 - 0.01 15.4 0.6 0.025 14.1 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain Zn_clus PF00172.13 CCH61359.1 - 1.8e-07 30.9 9.5 3.2e-07 30.1 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.15 CCH61360.1 - 4e-55 186.6 15.4 4.7e-55 186.3 10.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related 7TMR-DISM_7TM PF07695.6 CCH61360.1 - 0.0019 17.8 13.7 0.0019 17.8 9.5 2.0 1 1 1 2 2 2 1 7TM diverse intracellular signalling DUF981 PF06168.6 CCH61360.1 - 0.011 15.5 3.2 0.021 14.6 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF981) Cation_ATPase_C PF00689.16 CCH61360.1 - 0.13 11.7 9.3 0.39 10.2 3.7 2.4 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF998 PF06197.8 CCH61360.1 - 0.38 10.0 6.1 1.1 8.5 0.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF998) TPP_enzyme_M PF00205.17 CCH61361.1 - 1.6e-34 118.6 0.0 3.6e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCH61361.1 - 7e-33 113.5 0.0 1e-32 112.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCH61361.1 - 6.7e-13 48.4 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CCH61361.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit PLA2_B PF01735.13 CCH61362.1 - 6e-218 723.9 1.2 8.1e-218 723.5 0.8 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Pex14_N PF04695.8 CCH61362.1 - 0.23 11.4 4.4 0.45 10.5 3.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apt1 PF10351.4 CCH61362.1 - 1.4 7.6 6.2 2.5 6.8 4.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Herpes_capsid PF06112.6 CCH61362.1 - 1.6 8.7 13.0 3.1 7.8 9.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 CCH61362.1 - 2.8 6.1 11.6 4.4 5.4 8.0 1.2 1 0 0 1 1 1 0 Transmembrane protein RTC PF01137.16 CCH61363.1 - 9.8e-59 197.8 0.0 1.2e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCH61363.1 - 3.2e-28 97.7 0.0 5e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 CCH61364.1 - 9.5e-21 73.7 0.5 2.2e-20 72.5 0.0 1.9 2 0 0 2 2 2 1 PX domain Minor_capsid_1 PF10665.4 CCH61364.1 - 0.0069 16.2 1.0 0.19 11.5 0.1 2.5 2 0 0 2 2 2 1 Minor capsid protein Polyketide_cyc PF03364.15 CCH61365.1 - 2.7e-15 56.5 0.0 3.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CCH61365.1 - 0.0079 16.3 0.0 0.0093 16.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2076 PF09849.4 CCH61366.1 - 1.1e-06 28.9 9.4 1.3e-06 28.6 6.5 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CCH61366.1 - 2.4e-05 24.0 3.9 3.6e-05 23.5 2.7 1.3 1 0 0 1 1 1 1 CHCH domain DUF605 PF04652.11 CCH61366.1 - 0.0019 17.6 5.0 0.0021 17.5 3.5 1.1 1 0 0 1 1 1 1 Vta1 like COX6B PF02297.12 CCH61366.1 - 0.18 11.8 2.2 0.27 11.2 1.5 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Nucleoporin_FG PF13634.1 CCH61366.1 - 1.2 9.3 15.9 2.4 8.3 11.0 1.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region DUF2360 PF10152.4 CCH61366.1 - 3 8.1 9.5 7.2 6.8 0.1 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Med3 PF11593.3 CCH61366.1 - 8.6 5.4 11.3 10 5.2 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Topoisom_I_N PF02919.10 CCH61368.1 - 1.8e-101 337.8 1.2 1.8e-101 337.8 0.8 3.4 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CCH61368.1 - 8.5e-86 286.8 0.8 8.5e-86 286.8 0.6 2.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CCH61368.1 - 4.2e-32 109.6 0.4 4.2e-32 109.6 0.3 2.7 2 1 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 CCH61368.1 - 0.029 13.5 0.0 0.077 12.1 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family RNA_pol_L_2 PF13656.1 CCH61369.1 - 4e-26 90.2 0.1 5e-26 89.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCH61369.1 - 6.1e-11 41.2 0.0 8.2e-11 40.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PAH PF02671.16 CCH61370.1 - 4.8e-44 147.7 9.2 6.2e-18 64.1 0.8 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CCH61370.1 - 9.4e-32 108.7 0.1 3.8e-31 106.8 0.1 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor Histone PF00125.19 CCH61371.1 - 8e-23 80.3 0.0 1e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH61371.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DAGK_cat PF00781.19 CCH61372.1 - 3.2e-25 88.0 0.0 5.1e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop14 PF04147.7 CCH61372.1 - 0.00011 20.3 12.6 0.00014 20.0 8.7 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 CCH61372.1 - 0.0019 17.5 14.9 0.0031 16.8 10.3 1.3 1 0 0 1 1 1 1 SDA1 Prothymosin PF03247.9 CCH61372.1 - 0.34 11.0 23.0 0.58 10.3 16.0 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family CDC45 PF02724.9 CCH61372.1 - 1.9 6.4 17.7 2 6.3 11.2 1.7 2 0 0 2 2 2 0 CDC45-like protein DUF572 PF04502.8 CCH61372.1 - 1.9 7.6 21.2 0.1 11.8 8.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Ras PF00071.17 CCH61373.1 - 3.7e-57 192.2 0.3 4.2e-57 192.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH61373.1 - 2.2e-22 79.8 0.2 5.7e-22 78.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCH61373.1 - 7.9e-16 57.7 0.6 8.8e-16 57.6 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCH61373.1 - 9.7e-06 24.9 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCH61373.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCH61373.1 - 1.6e-05 24.1 0.1 2e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCH61373.1 - 0.00012 21.5 0.1 0.00067 19.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 CCH61373.1 - 0.00056 19.6 0.9 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CCH61373.1 - 0.0013 18.8 0.0 0.0061 16.6 0.0 1.9 1 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCH61373.1 - 0.0061 16.0 0.4 0.032 13.7 0.2 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CCH61373.1 - 0.0065 16.0 0.1 0.28 10.6 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 CCH61373.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCH61373.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCH61373.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CCH61373.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Dynactin_p22 PF07426.6 CCH61374.1 - 0.00037 19.8 1.2 0.00078 18.7 0.8 1.5 1 0 0 1 1 1 1 Dynactin subunit p22 DUF4476 PF14771.1 CCH61374.1 - 0.061 13.3 0.2 0.061 13.3 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) DUF1838 PF08894.6 CCH61375.1 - 0.02 14.0 0.7 0.046 12.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1838) Rtt102p PF09510.5 CCH61375.1 - 0.059 13.3 6.2 0.028 14.4 2.1 1.9 1 1 0 2 2 2 0 Rtt102p-like transcription regulator protein Oxidored_FMN PF00724.15 CCH61376.1 - 1.2e-118 396.0 0.0 1.4e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SinI PF08671.5 CCH61376.1 - 1.5 8.3 4.1 2.6 7.5 0.6 2.8 2 1 0 2 2 2 0 Anti-repressor SinI RHD3 PF05879.7 CCH61377.1 - 3.3e-218 726.2 28.2 1.5e-217 724.0 19.5 1.8 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 CCH61377.1 - 0.00038 20.3 0.1 0.0019 18.1 0.1 2.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCH61377.1 - 0.0004 20.2 0.0 0.0004 20.2 0.0 2.7 3 0 0 3 3 3 1 Dynamin family Miro PF08477.8 CCH61377.1 - 0.0044 17.5 0.2 0.036 14.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein DUF410 PF04190.8 CCH61378.1 - 1.1e-68 231.6 1.9 1.3e-68 231.3 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.23 CCH61379.1 - 3.1e-14 52.7 0.0 3.6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain LEF-9 PF05094.7 CCH61379.1 - 0.0098 14.3 0.1 0.014 13.7 0.0 1.1 1 0 0 1 1 1 1 Late expression factor 9 (LEF-9) NUDIX_2 PF13869.1 CCH61379.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotide hydrolase Chromadorea_ALT PF05535.7 CCH61379.1 - 0.26 11.3 1.7 1.7 8.7 0.1 2.6 1 1 0 2 2 2 0 Chromadorea ALT protein PalH PF08733.5 CCH61380.1 - 6.4e-33 114.0 44.3 6.4e-33 114.0 30.7 1.9 2 1 0 2 2 2 1 PalH/RIM21 bZIP_1 PF00170.16 CCH61382.1 - 6.9e-10 38.7 9.5 1.6e-09 37.5 6.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor LAGLIDADG_WhiA PF14527.1 CCH61382.1 - 0.076 12.8 0.8 0.17 11.8 0.6 1.6 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain NYD-SP28_assoc PF14775.1 CCH61382.1 - 0.46 10.2 4.8 0.97 9.1 3.3 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.10 CCH61382.1 - 0.48 10.2 10.1 1.2 8.9 7.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper AAA_2 PF07724.9 CCH61383.1 - 1.1e-51 175.1 0.4 1.6e-48 164.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCH61383.1 - 4.4e-26 90.5 0.2 4.4e-26 90.5 0.2 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCH61383.1 - 2.2e-21 76.4 0.1 1.9e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH61383.1 - 9.6e-17 61.0 1.2 1.7e-12 47.2 0.0 3.7 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH61383.1 - 5.2e-15 55.9 0.1 0.00023 21.1 0.0 4.0 2 2 1 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 CCH61383.1 - 7.7e-10 39.0 0.0 0.00065 19.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCH61383.1 - 9e-09 35.3 0.0 0.0015 18.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CCH61383.1 - 1.2e-07 31.3 0.1 6e-06 25.8 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCH61383.1 - 6e-06 25.7 0.0 0.048 13.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 CCH61383.1 - 7.3e-06 26.8 6.0 0.019 15.7 0.0 3.9 3 1 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CCH61383.1 - 9.9e-06 25.4 16.8 0.028 14.1 0.0 5.2 3 2 1 4 4 3 2 Archaeal ATPase Zeta_toxin PF06414.7 CCH61383.1 - 2.9e-05 23.2 0.0 0.0021 17.1 0.0 3.1 2 1 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 CCH61383.1 - 3.1e-05 23.9 1.2 0.0045 16.9 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.7 CCH61383.1 - 0.00014 21.6 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 CCH61383.1 - 0.00014 21.1 0.1 0.047 12.8 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function, DUF258 MobB PF03205.9 CCH61383.1 - 0.00018 21.2 0.0 0.14 11.8 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCH61383.1 - 0.00028 20.8 0.0 0.27 11.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCH61383.1 - 0.0004 20.6 11.5 0.04 14.2 0.0 4.0 4 1 0 4 4 3 2 AAA domain PduV-EutP PF10662.4 CCH61383.1 - 0.00076 18.9 0.0 0.73 9.3 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CCH61383.1 - 0.00092 18.6 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 CCH61383.1 - 0.001 18.7 0.1 1.2 8.6 0.0 3.4 3 1 1 4 4 4 1 AAA domain RNA_helicase PF00910.17 CCH61383.1 - 0.0017 18.5 0.1 2.7 8.2 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_19 PF13245.1 CCH61383.1 - 0.002 17.8 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 CCH61383.1 - 0.0035 17.6 7.0 0.26 11.5 0.0 3.8 3 2 0 3 3 2 1 ABC transporter UPF0079 PF02367.12 CCH61383.1 - 0.0042 16.7 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 CCH61383.1 - 0.0069 15.8 0.0 1.3 8.4 0.0 3.0 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 CCH61383.1 - 0.0098 15.0 0.0 1.2 8.2 0.0 3.0 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCH61383.1 - 0.011 14.9 0.2 2.7 7.1 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein TrwB_AAD_bind PF10412.4 CCH61383.1 - 0.012 14.2 0.0 0.83 8.2 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.1 CCH61383.1 - 0.013 14.8 0.6 3.7 6.9 0.0 3.3 2 2 0 2 2 2 0 AAA domain Torsin PF06309.6 CCH61383.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 CCH61383.1 - 0.028 14.3 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CCH61383.1 - 0.029 13.9 0.0 3.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.6 CCH61383.1 - 0.03 13.9 0.0 0.69 9.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CCH61383.1 - 0.037 14.5 0.5 1.2 9.6 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein T2SE PF00437.15 CCH61383.1 - 0.04 12.8 3.5 0.13 11.1 1.4 2.5 2 1 0 2 2 2 0 Type II/IV secretion system protein DUF1090 PF06476.7 CCH61383.1 - 0.44 10.2 12.9 0.63 9.7 0.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF972 PF06156.8 CCH61383.1 - 7 7.0 12.2 1.2 9.4 4.8 2.5 3 0 0 3 3 1 0 Protein of unknown function (DUF972) TPR_11 PF13414.1 CCH61384.1 - 1.2e-58 194.6 19.6 2.7e-16 58.9 0.0 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 CCH61384.1 - 9.9e-48 157.8 11.5 6.7e-09 34.9 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61384.1 - 2.8e-39 129.8 10.6 7.3e-07 28.6 0.0 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 CCH61384.1 - 5.9e-24 83.8 9.0 4.1e-10 39.4 0.6 6.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCH61384.1 - 1.5e-22 77.6 13.0 0.00031 20.3 0.1 8.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCH61384.1 - 5e-22 78.0 1.3 0.0013 19.3 0.0 6.6 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 CCH61384.1 - 8.4e-22 75.6 1.7 0.0012 19.2 0.0 8.9 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCH61384.1 - 9.8e-20 68.7 4.7 0.0061 16.2 0.0 7.2 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCH61384.1 - 4.3e-15 55.8 8.4 0.062 13.6 0.0 7.3 5 2 1 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCH61384.1 - 2.2e-12 46.1 3.0 0.43 10.8 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCH61384.1 - 2.2e-09 37.0 0.0 0.0007 19.4 0.0 5.5 4 1 2 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CCH61384.1 - 2e-08 34.2 10.8 0.02 14.9 1.2 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCH61384.1 - 1.4e-06 28.3 10.5 13 6.5 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCH61384.1 - 2.3e-05 24.1 0.1 0.11 12.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.4 CCH61384.1 - 0.00083 18.0 7.0 0.0014 17.3 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) MIT PF04212.13 CCH61384.1 - 0.0069 16.2 13.9 5.6 6.9 0.2 5.5 4 1 0 4 4 4 1 MIT (microtubule interacting and transport) domain MAS20 PF02064.10 CCH61384.1 - 0.027 14.3 3.1 3.1 7.7 0.0 4.0 3 1 2 5 5 4 0 MAS20 protein import receptor TPR_20 PF14561.1 CCH61384.1 - 0.032 14.3 4.3 9.5 6.4 0.1 4.5 4 3 2 6 6 5 0 Tetratricopeptide repeat RPN7 PF10602.4 CCH61384.1 - 0.032 13.6 13.3 0.76 9.1 0.0 5.5 3 1 2 5 5 5 0 26S proteasome subunit RPN7 Foie-gras_1 PF11817.3 CCH61384.1 - 0.062 12.7 3.5 1.3 8.4 0.9 3.1 1 1 1 2 2 2 0 Foie gras liver health family 1 HRDC PF00570.18 CCH61384.1 - 0.095 12.4 0.9 6.2 6.6 0.0 2.6 2 0 0 2 2 2 0 HRDC domain DUF357 PF04010.8 CCH61384.1 - 0.12 12.0 4.9 22 4.8 0.0 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF357) SHNi-TPR PF10516.4 CCH61384.1 - 0.19 10.9 6.6 39 3.6 0.0 5.5 7 0 0 7 7 7 0 SHNi-TPR TPR_3 PF07720.7 CCH61384.1 - 0.3 10.9 11.7 4.7 7.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MAGP PF05507.6 CCH61384.1 - 1.3 8.8 4.4 3.7 7.3 0.1 3.1 3 1 1 4 4 3 0 Microfibril-associated glycoprotein (MAGP) XPC-binding PF09280.6 CCH61384.1 - 1.9 7.9 11.1 0.28 10.6 1.8 2.9 2 1 0 2 2 2 0 XPC-binding domain SET PF00856.23 CCH61385.1 - 1.2e-09 38.7 0.3 1.1e-08 35.6 0.2 2.2 1 1 0 1 1 1 1 SET domain WD40 PF00400.27 CCH61386.1 - 8.7e-13 47.6 5.2 1.6e-06 27.7 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCH61386.1 - 0.002 17.8 0.2 1 9.1 0.0 3.6 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CPSF_A PF03178.10 CCH61386.1 - 0.047 12.7 0.3 3.1 6.7 0.1 2.4 1 1 1 2 2 2 0 CPSF A subunit region Pex24p PF06398.6 CCH61387.1 - 3.5e-79 266.2 6.7 4.3e-79 265.9 4.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpr2 PF04032.11 CCH61388.1 - 3.2e-11 42.9 0.1 3.2e-11 42.9 0.1 2.0 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 CCH61388.1 - 0.098 11.8 5.3 0.21 10.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Thioredoxin_2 PF13098.1 CCH61388.1 - 0.099 12.8 1.2 0.16 12.2 0.8 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain SIR2 PF02146.12 CCH61389.1 - 9.8e-35 119.8 0.0 2.6e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Sir2 family UCH PF00443.24 CCH61389.1 - 0.0033 16.5 0.0 0.0051 15.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pkinase PF00069.20 CCH61390.1 - 2.7e-77 259.4 0.1 4.1e-77 258.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61390.1 - 3.7e-38 131.0 0.0 6.5e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 CCH61390.1 - 1.4e-18 66.8 0.5 1.4e-18 66.8 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 CCH61390.1 - 2.4e-10 39.8 0.0 4.7e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 CCH61390.1 - 7.7e-05 21.4 0.4 0.00012 20.7 0.3 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 CCH61390.1 - 0.0042 16.1 0.1 0.0097 14.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH61390.1 - 0.029 14.1 0.4 0.34 10.5 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sdh5 PF03937.11 CCH61390.1 - 0.1 12.2 0.1 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase LSM PF01423.17 CCH61391.1 - 1.7e-17 62.7 0.1 2.4e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCH61391.1 - 0.004 17.0 0.1 0.0077 16.1 0.1 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain Prefoldin PF02996.12 CCH61393.1 - 1.7e-35 121.2 3.8 2.3e-35 120.8 2.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF3779 PF12621.3 CCH61393.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphate metabolism protein CENP-F_leu_zip PF10473.4 CCH61393.1 - 0.23 11.3 10.1 0.95 9.3 0.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CCH61393.1 - 0.97 8.9 6.5 7.6 6.0 0.2 2.1 2 0 0 2 2 2 0 IncA protein SlyX PF04102.7 CCH61393.1 - 3.8 7.9 5.7 3.8 7.9 0.2 2.8 2 1 1 3 3 3 0 SlyX DUF2611 PF11022.3 CCH61394.1 - 9.3e-16 57.6 0.0 1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF3321 PF11968.3 CCH61395.1 - 1.2e-72 244.1 3.8 1.2e-72 244.1 2.7 1.8 2 1 0 2 2 2 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CCH61395.1 - 3.6e-07 30.0 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_Tnp_1_2 PF13022.1 CCH61395.1 - 0.0047 16.7 0.8 0.012 15.4 0.5 1.7 1 0 0 1 1 1 1 Helix-turn-helix of insertion element transposase Methyltransf_11 PF08241.7 CCH61395.1 - 0.0055 17.1 0.1 0.019 15.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH61395.1 - 0.024 15.0 1.3 0.045 14.2 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 CCH61395.1 - 0.033 13.4 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 CCH61395.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DEAD PF00270.24 CCH61396.1 - 1.6e-36 125.3 0.0 4.3e-36 123.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61396.1 - 2.8e-23 81.5 0.2 1.2e-22 79.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain NACHT PF05729.7 CCH61396.1 - 0.028 14.0 0.0 0.2 11.2 0.0 2.3 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CCH61396.1 - 2.7 8.1 8.6 0.46 10.6 0.2 3.7 3 1 1 4 4 4 0 AAA domain ADH_N PF08240.7 CCH61397.1 - 1.7e-29 101.7 0.4 3.8e-29 100.6 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH61397.1 - 7.9e-27 93.3 0.8 1.2e-26 92.7 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCH61397.1 - 0.00015 22.6 0.1 0.00032 21.5 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH61398.1 - 6.1e-30 103.1 0.5 1.2e-29 102.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH61398.1 - 1.2e-26 92.8 0.4 1.9e-26 92.1 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCH61398.1 - 4.4e-05 24.3 0.1 0.00012 22.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3937 PF13073.1 CCH61399.1 - 1.6 8.6 7.9 1.5 8.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) DUF2165 PF09933.4 CCH61400.1 - 0.0071 16.0 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2165) D5_N PF08706.6 CCH61400.1 - 0.015 15.4 2.8 0.024 14.7 1.9 1.3 1 0 0 1 1 1 0 D5 N terminal like DUF3337 PF11816.3 CCH61401.1 - 4.4e-58 197.2 10.4 4.4e-58 197.2 7.2 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3337) WD40 PF00400.27 CCH61401.1 - 4.9e-12 45.2 13.3 0.00017 21.3 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat PEPcase_2 PF14010.1 CCH61401.1 - 0.045 12.0 0.7 0.083 11.1 0.5 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF2115 PF09888.4 CCH61401.1 - 1.9 8.5 6.3 0.41 10.7 1.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Thioredoxin PF00085.15 CCH61402.1 - 1.2e-15 57.0 0.0 3.6e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CCH61402.1 - 0.00018 21.5 0.3 0.00053 20.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 CCH61402.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CCH61402.1 - 0.016 15.4 0.3 0.044 13.9 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain zf-FCS PF06467.9 CCH61402.1 - 0.036 13.6 0.8 0.08 12.5 0.5 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Zn_clus PF00172.13 CCH61403.1 - 2.8e-08 33.5 12.4 5.1e-08 32.6 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.9 CCH61405.1 - 6.3e-40 134.5 14.5 1.1e-21 76.1 0.7 3.0 3 0 0 3 3 3 2 PQ loop repeat Steroid_dh PF02544.11 CCH61405.1 - 0.044 13.5 0.7 0.044 13.5 0.5 2.5 2 1 1 3 3 3 0 3-oxo-5-alpha-steroid 4-dehydrogenase MtN3_slv PF03083.11 CCH61405.1 - 2.1 8.2 7.0 0.46 10.3 0.7 2.7 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF3784 PF12650.2 CCH61405.1 - 6.1 6.8 10.4 1.4 8.9 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) Rep_fac_C PF08542.6 CCH61406.1 - 9.2e-17 60.8 0.3 2.1e-16 59.6 0.2 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 CCH61406.1 - 2e-13 50.6 0.0 4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCH61406.1 - 5.5e-13 48.8 0.1 4.9e-11 42.5 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CCH61406.1 - 5.7e-10 38.4 0.3 9.9e-05 21.2 0.0 2.1 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CCH61406.1 - 1.2e-08 34.9 0.0 2.7e-08 33.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCH61406.1 - 1.7e-06 28.1 0.0 5e-05 23.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 CCH61406.1 - 2.8e-06 26.9 0.0 7.9e-06 25.5 0.0 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH61406.1 - 3.6e-06 27.1 0.1 0.015 15.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CCH61406.1 - 5.9e-06 25.9 0.0 9.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 CCH61406.1 - 1.1e-05 24.5 0.1 0.00012 21.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CCH61406.1 - 0.00016 20.8 0.1 0.0025 16.9 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 CCH61406.1 - 0.00035 20.1 0.2 0.00065 19.2 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 CCH61406.1 - 0.00061 19.3 0.0 0.035 13.5 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain NTPase_1 PF03266.10 CCH61406.1 - 0.0017 18.1 0.1 0.018 14.7 0.0 2.4 1 1 1 2 2 2 1 NTPase FtsK_SpoIIIE PF01580.13 CCH61406.1 - 0.0019 17.7 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ArgK PF03308.11 CCH61406.1 - 0.005 15.6 0.0 0.032 12.9 0.0 2.1 2 1 1 3 3 3 1 ArgK protein AAA_19 PF13245.1 CCH61406.1 - 0.0063 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CCH61406.1 - 0.013 15.7 0.6 0.042 14.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CCH61406.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 CCH61406.1 - 0.025 14.5 0.0 0.082 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 CCH61406.1 - 0.026 14.0 0.1 0.6 9.5 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.17 CCH61406.1 - 0.034 13.0 0.1 0.067 12.0 0.0 1.6 1 1 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 CCH61406.1 - 0.051 13.8 0.1 0.13 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CCH61406.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CCH61406.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 CCH61406.1 - 0.07 12.8 0.2 0.78 9.4 0.0 2.5 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CCH61406.1 - 0.073 12.7 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 NACHT domain KTI12 PF08433.5 CCH61406.1 - 0.081 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 CCH61406.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain YL1 PF05764.8 CCH61407.1 - 4.1e-53 180.4 39.8 4.1e-53 180.4 27.6 3.4 2 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 CCH61407.1 - 3.4e-11 42.4 1.1 5.6e-11 41.7 0.8 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Snf7 PF03357.16 CCH61408.1 - 3.4e-38 130.7 20.0 4.1e-38 130.4 13.8 1.1 1 0 0 1 1 1 1 Snf7 FliJ PF02050.11 CCH61408.1 - 0.0071 16.3 9.6 0.0071 16.3 6.6 2.4 1 1 2 3 3 3 1 Flagellar FliJ protein Fmp27_WPPW PF10359.4 CCH61408.1 - 0.011 14.2 6.6 0.014 13.8 4.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.10 CCH61408.1 - 0.016 14.4 8.6 0.019 14.1 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.3 CCH61408.1 - 0.019 15.0 17.2 0.12 12.3 11.8 2.1 1 1 0 1 1 1 0 YlqD protein Atg14 PF10186.4 CCH61408.1 - 0.035 13.0 13.8 0.046 12.6 9.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 CCH61408.1 - 0.071 12.7 12.5 1.1 8.8 8.6 2.1 1 1 0 1 1 1 0 Mnd1 family Vps4_C PF09336.5 CCH61408.1 - 0.15 11.9 3.1 2.3 8.2 0.5 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF771 PF05595.6 CCH61408.1 - 0.15 12.0 2.7 0.49 10.3 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF771) IL2 PF00715.12 CCH61408.1 - 0.15 11.7 6.9 0.23 11.1 4.7 1.3 1 1 0 1 1 1 0 Interleukin 2 TrfA PF07042.6 CCH61408.1 - 0.16 10.7 1.7 0.22 10.3 1.2 1.1 1 0 0 1 1 1 0 TrfA protein NIT PF08376.5 CCH61408.1 - 0.24 10.9 10.1 0.08 12.4 3.6 2.2 1 1 1 2 2 2 0 Nitrate and nitrite sensing DUF2064 PF09837.4 CCH61408.1 - 0.27 10.8 3.5 0.15 11.6 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF3584 PF12128.3 CCH61408.1 - 0.3 8.3 17.6 0.35 8.1 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin_1 PF12718.2 CCH61408.1 - 0.35 10.6 14.8 0.16 11.8 7.9 2.0 1 1 1 2 2 2 0 Tropomyosin like IncA PF04156.9 CCH61408.1 - 0.48 10.0 17.6 3.8 7.0 11.5 2.2 1 1 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 CCH61408.1 - 0.93 8.6 8.2 1.1 8.3 4.9 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Toxin_52 PF15605.1 CCH61408.1 - 1.5 8.7 12.6 0.36 10.7 0.3 3.3 1 1 1 3 3 3 0 Putative toxin 52 OmpH PF03938.9 CCH61408.1 - 2.2 8.1 23.8 47 3.8 16.5 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 CCH61408.1 - 2.6 6.3 11.5 1.9 6.8 6.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) bZIP_1 PF00170.16 CCH61408.1 - 3 7.8 8.9 5.3 7.0 0.1 3.5 2 1 1 3 3 3 0 bZIP transcription factor Prefoldin PF02996.12 CCH61408.1 - 3.2 7.4 14.0 0.071 12.7 1.0 3.3 1 1 3 4 4 4 0 Prefoldin subunit Serine_rich PF08824.5 CCH61408.1 - 3.4 7.3 12.6 2.5 7.7 6.3 2.4 1 1 1 2 2 2 0 Serine rich protein interaction domain Cep57_MT_bd PF06657.8 CCH61408.1 - 4.4 7.3 12.5 0.53 10.2 4.1 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF972 PF06156.8 CCH61408.1 - 4.7 7.6 14.4 32 4.9 0.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 CCH61408.1 - 5 7.0 10.5 2.7 7.9 0.2 3.6 3 2 1 4 4 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 CCH61408.1 - 8.9 6.1 9.2 4.1 7.2 2.3 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 rve PF00665.21 CCH61409.1 - 1.7e-09 37.7 0.1 4.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Tubulin-binding PF00418.14 CCH61409.1 - 0.016 14.8 0.0 0.05 13.3 0.0 1.8 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat AcetylCoA_hydro PF02550.10 CCH61410.1 - 2.6e-66 223.1 0.0 5.2e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 CCH61410.1 - 2e-39 134.7 0.0 3.1e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 CCH61410.1 - 0.061 12.4 0.0 0.46 9.6 0.0 2.3 3 0 0 3 3 3 0 Coenzyme A transferase CitF PF04223.7 CCH61410.1 - 0.14 10.7 0.0 0.26 9.9 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) DNA_topoisoIV PF00521.15 CCH61411.1 - 2e-124 415.7 0.9 2e-124 415.7 0.6 2.4 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CCH61411.1 - 1.2e-33 115.7 4.1 3.3e-33 114.3 2.8 1.8 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CCH61411.1 - 2.2e-12 46.8 0.0 1e-11 44.6 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CCH61411.1 - 3.3e-10 39.6 0.0 1.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase C2 PF00168.25 CCH61412.1 - 4e-48 161.1 5.3 1.7e-20 72.6 0.2 4.9 5 0 0 5 5 5 4 C2 domain NT-C2 PF10358.4 CCH61412.1 - 0.0087 15.5 0.3 0.034 13.6 0.2 2.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PA28_beta PF02252.13 CCH61412.1 - 0.014 14.8 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit DUF2404 PF10296.4 CCH61412.1 - 0.094 12.8 0.4 2 8.6 0.0 2.7 1 1 1 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) OST3_OST6 PF04756.8 CCH61413.1 - 1.2e-20 73.7 5.2 1.2e-20 73.7 3.6 2.0 2 1 0 2 2 2 1 OST3 / OST6 family Thioredoxin PF00085.15 CCH61413.1 - 0.0033 17.0 0.0 0.0061 16.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF4491 PF14898.1 CCH61413.1 - 0.48 10.6 5.9 6.1 7.0 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) MKT1_C PF12246.3 CCH61414.1 - 3.3e-62 209.6 4.6 8.2e-62 208.3 3.1 1.7 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CCH61414.1 - 1e-27 96.2 0.1 3e-27 94.7 0.0 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CCH61414.1 - 6.9e-22 77.6 0.0 2.8e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 CCH61414.1 - 5.7e-09 35.9 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 4HBT PF03061.17 CCH61415.1 - 2.5e-05 24.3 0.2 0.024 14.7 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily EF-hand_4 PF12763.2 CCH61416.1 - 6.4e-49 164.0 5.3 1.2e-45 153.4 0.8 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CCH61416.1 - 3e-31 108.5 8.3 6.4e-31 107.5 5.8 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 FlxA PF14282.1 CCH61416.1 - 0.0026 17.6 6.3 0.0026 17.6 4.4 3.0 2 1 1 3 3 3 1 FlxA-like protein DUF4140 PF13600.1 CCH61416.1 - 0.0051 17.2 1.3 0.46 10.9 0.4 2.4 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 CCH61416.1 - 0.015 15.1 8.4 0.11 12.3 2.6 2.5 2 0 0 2 2 2 0 Tropomyosin like EF-hand_7 PF13499.1 CCH61416.1 - 0.015 15.4 0.3 0.33 11.1 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair Adeno_PIX PF03955.9 CCH61416.1 - 0.45 11.0 6.8 0.9 10.0 0.6 2.6 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 CCH61416.1 - 0.69 9.4 15.7 0.72 9.4 0.4 2.5 1 1 1 2 2 2 0 IncA protein SlyX PF04102.7 CCH61416.1 - 2.5 8.5 7.9 4.5 7.7 1.4 2.8 2 0 0 2 2 2 0 SlyX DUF2217 PF10265.4 CCH61416.1 - 2.8 6.6 8.5 0.37 9.5 2.8 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Filo_VP35 PF02097.10 CCH61416.1 - 2.9 7.0 7.6 1.2 8.2 2.4 1.9 1 1 1 2 2 2 0 Filoviridae VP35 Lzipper-MIP1 PF14389.1 CCH61416.1 - 4 7.6 13.4 65 3.7 8.8 2.7 2 1 0 2 2 1 0 Leucine-zipper of ternary complex factor MIP1 Tweety PF04906.8 CCH61416.1 - 4.8 5.4 7.9 13 4.0 2.0 2.5 2 1 0 2 2 2 0 Tweety Rho_Binding PF08912.6 CCH61416.1 - 5 7.4 16.4 2.9 8.2 5.8 3.0 3 0 0 3 3 3 0 Rho Binding EF-hand_1 PF00036.27 CCH61416.1 - 5.9 6.4 9.8 0.17 11.2 1.8 2.3 3 0 0 3 3 2 0 EF hand CENP-F_leu_zip PF10473.4 CCH61416.1 - 7.4 6.4 18.8 2 8.2 6.5 2.6 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 CCH61416.1 - 8.1 6.3 18.7 14 5.5 0.4 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_S13 PF00416.17 CCH61417.1 - 1.7e-23 83.1 0.0 2e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 IMS_HHH PF11798.3 CCH61417.1 - 0.0028 17.6 0.3 0.036 14.1 0.0 2.7 3 0 0 3 3 3 1 IMS family HHH motif FbpA PF05833.6 CCH61417.1 - 0.0042 15.6 0.0 0.0042 15.6 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Tropomyosin_1 PF12718.2 CCH61418.1 - 5.7e-44 149.4 49.3 6.8e-44 149.1 34.1 1.1 1 0 0 1 1 1 1 Tropomyosin like CENP-F_leu_zip PF10473.4 CCH61418.1 - 7.7e-06 25.8 46.0 0.00082 19.2 10.4 3.0 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.15 CCH61418.1 - 1.6e-05 24.1 43.9 0.0025 16.9 15.7 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 CCH61418.1 - 0.00023 21.1 27.6 0.033 14.2 7.9 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein Filament PF00038.16 CCH61418.1 - 0.00033 20.2 34.7 0.0042 16.5 12.4 2.0 1 1 1 2 2 2 2 Intermediate filament protein Sec2p PF06428.6 CCH61418.1 - 0.00039 20.2 18.3 0.00039 20.2 12.7 3.0 1 1 2 3 3 3 1 GDP/GTP exchange factor Sec2p MbeD_MobD PF04899.7 CCH61418.1 - 0.002 17.9 1.2 0.002 17.9 0.8 3.0 2 1 1 3 3 3 1 MbeD/MobD like ATG16 PF08614.6 CCH61418.1 - 0.0031 17.3 38.8 0.041 13.7 8.2 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) IncA PF04156.9 CCH61418.1 - 0.0034 17.0 41.3 0.09 12.3 14.6 2.1 1 1 1 2 2 2 2 IncA protein WXG100 PF06013.7 CCH61418.1 - 0.0036 17.2 17.1 0.32 11.0 0.7 3.6 2 1 1 3 3 3 2 Proteins of 100 residues with WXG GAS PF13851.1 CCH61418.1 - 0.0039 16.4 42.6 0.25 10.5 19.5 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CCH61418.1 - 0.004 16.9 54.3 0.065 13.0 11.9 3.4 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 CCH61418.1 - 0.0074 16.0 47.2 0.33 10.6 19.9 2.4 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CCH61418.1 - 0.0099 13.6 43.0 0.017 12.8 29.8 1.3 1 1 0 1 1 1 1 Myosin tail HALZ PF02183.13 CCH61418.1 - 0.01 15.4 1.3 0.01 15.4 0.9 5.2 3 2 2 5 5 5 0 Homeobox associated leucine zipper Laminin_II PF06009.7 CCH61418.1 - 0.011 15.5 26.2 0.27 10.9 8.3 2.2 1 1 1 2 2 2 0 Laminin Domain II EzrA PF06160.7 CCH61418.1 - 0.013 13.7 34.5 0.029 12.5 23.9 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Mod_r PF07200.8 CCH61418.1 - 0.014 15.2 35.4 0.4 10.5 6.9 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 CCH61418.1 - 0.015 15.4 33.2 0.078 13.1 6.3 3.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 CCH61418.1 - 0.016 15.1 43.7 0.042 13.7 5.8 4.3 2 1 2 4 4 4 0 bZIP transcription factor ADIP PF11559.3 CCH61418.1 - 0.018 14.9 39.5 0.16 11.8 8.2 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 CCH61418.1 - 0.018 14.0 45.5 0.14 11.1 19.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 CCH61418.1 - 0.021 14.3 43.6 0.074 12.5 17.6 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4201 PF13870.1 CCH61418.1 - 0.022 14.2 33.0 0.075 12.4 11.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF3287 PF11690.3 CCH61418.1 - 0.029 14.4 4.8 0.029 14.4 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) DUF4200 PF13863.1 CCH61418.1 - 0.035 14.0 44.7 0.78 9.7 18.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.3 CCH61418.1 - 0.071 12.3 31.4 0.22 10.7 7.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Reo_sigmaC PF04582.7 CCH61418.1 - 0.15 11.1 8.9 0.24 10.5 0.9 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CCH61418.1 - 0.16 10.4 36.1 1.5 7.1 25.0 1.9 1 1 0 1 1 1 0 AAA domain FlaC_arch PF05377.6 CCH61418.1 - 0.16 11.8 32.4 0.98 9.3 2.8 4.7 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.1 CCH61418.1 - 0.18 11.1 38.9 1 8.7 26.9 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF904 PF06005.7 CCH61418.1 - 0.19 12.0 50.2 0.62 10.3 7.4 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 CCH61418.1 - 0.25 10.8 43.4 0.13 11.7 7.1 4.3 1 1 3 4 4 4 0 Septum formation initiator Atg14 PF10186.4 CCH61418.1 - 0.36 9.7 31.7 0.13 11.1 5.9 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 THOC7 PF05615.8 CCH61418.1 - 0.45 10.7 38.2 0.23 11.6 11.8 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 Lectin_N PF03954.9 CCH61418.1 - 0.47 9.8 15.9 0.066 12.6 3.0 2.5 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF972 PF06156.8 CCH61418.1 - 0.51 10.7 34.5 12 6.3 7.2 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WEMBL PF05701.6 CCH61418.1 - 0.53 8.6 42.3 0.32 9.4 8.9 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 CCH61418.1 - 0.58 7.4 34.7 0.65 7.2 24.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IFT57 PF10498.4 CCH61418.1 - 0.58 8.8 31.9 0.26 10.0 16.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 GOLGA2L5 PF15070.1 CCH61418.1 - 0.59 8.5 31.3 0.69 8.3 21.7 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DUF342 PF03961.8 CCH61418.1 - 0.62 8.4 35.4 0.31 9.4 10.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Rootletin PF15035.1 CCH61418.1 - 0.76 9.7 39.9 1.1 9.2 10.6 2.9 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF3540 PF12059.3 CCH61418.1 - 0.78 9.3 4.5 1.2 8.7 3.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3540) FemAB PF02388.11 CCH61418.1 - 0.78 8.3 30.2 0.098 11.3 10.2 2.0 1 1 1 2 2 2 0 FemAB family DivIVA PF05103.8 CCH61418.1 - 0.96 9.5 37.6 4.2 7.4 13.0 3.3 1 1 1 2 2 2 0 DivIVA protein Mnd1 PF03962.10 CCH61418.1 - 1.4 8.5 38.9 5.6 6.5 11.1 2.1 1 1 1 2 2 2 0 Mnd1 family Ax_dynein_light PF10211.4 CCH61418.1 - 1.4 8.6 40.9 0.73 9.6 11.7 3.0 1 1 3 4 4 4 0 Axonemal dynein light chain Rab5-bind PF09311.6 CCH61418.1 - 1.4 8.7 38.7 0.068 13.0 7.0 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DUF812 PF05667.6 CCH61418.1 - 1.6 7.1 34.0 6.1 5.2 18.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.15 CCH61418.1 - 1.6 8.5 49.2 1.2 8.9 6.5 4.1 1 1 2 4 4 4 0 Prefoldin subunit TBPIP PF07106.8 CCH61418.1 - 1.9 8.0 39.3 10 5.6 12.6 2.7 1 1 1 2 2 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 CCH61418.1 - 1.9 8.5 24.7 2.2 8.3 5.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.7 CCH61418.1 - 2.2 8.5 18.0 0.86 9.9 0.5 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 CCH61418.1 - 2.3 7.9 22.4 3.7 7.2 9.0 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 bZIP_2 PF07716.10 CCH61418.1 - 2.3 8.0 41.2 0.37 10.6 2.5 5.0 2 2 3 5 5 5 0 Basic region leucine zipper AATF-Che1 PF13339.1 CCH61418.1 - 2.4 8.3 26.2 3.1 7.9 1.6 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF1664 PF07889.7 CCH61418.1 - 2.4 7.9 20.4 3 7.6 7.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_3 PF13758.1 CCH61418.1 - 3.2 7.6 26.1 0.16 11.7 3.0 3.6 1 1 1 3 3 3 0 Prefoldin subunit CENP-K PF11802.3 CCH61418.1 - 3.2 6.9 27.5 0.028 13.6 8.4 2.1 1 1 1 2 2 2 0 Centromere-associated protein K Peptidase_S10 PF00450.17 CCH61418.1 - 3.4 6.7 10.3 4 6.4 7.2 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase Seryl_tRNA_N PF02403.17 CCH61418.1 - 3.7 7.6 38.0 2.2 8.3 4.9 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 CCH61418.1 - 4.6 5.8 37.3 1.5 7.3 11.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FliD_C PF07195.7 CCH61418.1 - 6.2 6.0 26.5 1.3 8.2 1.1 3.3 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Fmp27_WPPW PF10359.4 CCH61418.1 - 6.3 5.0 30.3 2 6.7 11.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Kinetocho_Slk19 PF12709.2 CCH61418.1 - 6.4 6.9 39.1 2.7 8.1 3.1 4.0 1 1 3 4 4 4 0 Central kinetochore-associated DASH_Dam1 PF08653.5 CCH61418.1 - 6.5 6.6 12.8 0.4 10.4 2.1 3.4 1 1 2 3 3 3 0 DASH complex subunit Dam1 BPL_N PF09825.4 CCH61418.1 - 6.6 5.3 9.7 8.1 5.1 6.7 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Uds1 PF15456.1 CCH61418.1 - 7.5 6.5 30.6 4.7 7.2 14.4 2.7 1 1 1 2 2 2 0 Up-regulated During Septation HOOK PF05622.7 CCH61418.1 - 8 4.1 35.5 13 3.3 24.6 1.5 1 1 0 1 1 1 0 HOOK protein CALCOCO1 PF07888.6 CCH61418.1 - 8 4.6 29.8 69 1.5 20.7 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HSP70 PF00012.15 CCH61418.1 - 8.3 4.1 25.1 9.3 4.0 17.4 1.2 1 0 0 1 1 1 0 Hsp70 protein Clr5 PF14420.1 CCH61418.1 - 8.3 6.3 8.7 0.26 11.1 0.9 2.4 3 1 0 3 3 1 0 Clr5 domain Adeno_PIX PF03955.9 CCH61418.1 - 9.8 6.7 18.3 20 5.7 1.7 3.0 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) CDC37_N PF03234.9 CCH61418.1 - 9.9 6.4 31.2 21 5.3 21.6 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Peptidase_M1 PF01433.15 CCH61419.1 - 2.4e-92 310.0 8.5 3.5e-92 309.4 5.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CCH61419.1 - 1.3e-44 152.8 0.3 1.7e-44 152.3 0.2 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCH61419.1 - 4.3e-13 49.4 0.0 7.2e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily BSP PF04450.7 CCH61419.1 - 0.029 13.8 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Peptidase of plants and bacteria DnaJ PF00226.26 CCH61420.1 - 6.7e-23 80.1 3.1 1.6e-22 78.9 2.2 1.7 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCH61420.1 - 2.6e-16 59.2 2.8 1.5e-13 50.4 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCH61420.1 - 3.1e-10 39.9 13.6 6.3e-10 38.9 9.4 1.6 1 0 0 1 1 1 1 DnaJ central domain DUF2486 PF10667.4 CCH61421.1 - 9.9 6.6 7.7 3.1 8.2 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2486) tRNA-synt_2 PF00152.15 CCH61422.1 - 5.4e-70 235.8 0.0 7.1e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CCH61422.1 - 4.1e-07 29.4 0.2 0.00069 18.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CCH61422.1 - 5.5e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCH61422.1 - 0.063 12.8 0.0 0.18 11.3 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF3605 PF12239.3 CCH61423.1 - 5.6e-39 133.5 7.7 6.8e-39 133.2 5.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) ArsC PF03960.10 CCH61423.1 - 0.19 11.8 1.2 0.41 10.7 0.8 1.5 1 0 0 1 1 1 0 ArsC family RNase_HII PF01351.13 CCH61424.1 - 2.1e-63 213.5 0.0 2.7e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Tom7 PF08038.7 CCH61425.1 - 1.3e-18 66.1 0.2 1.6e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 TOM7 family TALPID3 PF15324.1 CCH61426.1 - 0.038 11.3 2.7 0.046 11.0 1.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target ICAT PF06384.6 CCH61426.1 - 0.078 12.7 0.0 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Fork_head PF00250.13 CCH61427.1 - 9.1e-37 124.9 0.8 3.5e-36 123.1 0.6 2.0 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCH61427.1 - 6.2e-11 42.2 0.1 4.4e-10 39.5 0.0 2.6 1 1 1 2 2 2 1 FHA domain MOR2-PAG1_N PF14222.1 CCH61428.1 - 5.6e-165 550.1 8.9 1.8e-164 548.5 6.2 1.9 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CCH61428.1 - 6.1e-93 311.3 2.5 6.1e-93 311.3 1.7 2.7 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CCH61428.1 - 8e-25 86.6 12.4 6.4e-09 33.9 0.4 3.5 3 0 0 3 3 3 3 Cell morphogenesis central region AXH PF08517.7 CCH61429.1 - 0.19 11.8 1.0 0.49 10.5 0.7 1.6 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Mt_ATP-synt_B PF05405.9 CCH61429.1 - 0.65 9.4 14.7 1 8.7 10.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L6 PF00347.18 CCH61430.1 - 1e-25 89.9 11.6 5.8e-14 52.3 2.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 CCH61430.1 - 0.00099 18.2 0.3 0.0024 17.0 0.1 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Transket_pyr PF02779.19 CCH61431.1 - 1.6e-64 216.6 0.0 2.9e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCH61431.1 - 5.9e-56 189.3 0.0 7.7e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component LuxE PF04443.7 CCH61431.1 - 0.16 10.5 0.2 0.29 9.7 0.1 1.3 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE SUN PF03856.8 CCH61432.1 - 6.2e-106 353.2 13.5 9.4e-106 352.6 9.3 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) CMV_1a PF12467.3 CCH61432.1 - 0.0054 17.1 2.6 0.0082 16.5 1.8 1.2 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family DUF4643 PF15485.1 CCH61432.1 - 0.43 10.0 9.1 0.62 9.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) TFIIA PF03153.8 CCH61432.1 - 6.3 6.5 10.1 8.5 6.1 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 CCH61433.1 - 2.4e-41 141.6 28.4 7.9e-40 136.6 8.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH61433.1 - 8e-14 51.0 3.1 8e-14 51.0 2.2 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CCH61433.1 - 1e-06 27.2 4.3 1.9e-06 26.3 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2953 PF11167.3 CCH61433.1 - 0.028 14.3 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) MFS_1 PF07690.11 CCH61434.1 - 1.9e-36 125.4 30.1 5.5e-36 123.9 7.0 2.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH61434.1 - 5.7e-09 35.0 11.1 5.7e-09 35.0 7.7 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CCH61434.1 - 2.9e-07 29.0 5.3 4.9e-07 28.3 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DnaJ PF00226.26 CCH61435.1 - 2.5e-27 94.4 0.7 4e-27 93.7 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCH61435.1 - 5.1e-20 71.1 0.5 6.3e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCH61435.1 - 3.4e-13 49.4 17.8 7e-13 48.4 12.3 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCH61435.1 - 0.006 16.2 9.0 0.19 11.4 0.9 2.3 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 CCH61435.1 - 0.23 11.1 9.7 1.3 8.7 6.8 2.4 1 1 0 1 1 1 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 CCH61435.1 - 1.5 9.2 12.0 0.97 9.8 1.6 3.0 2 1 0 3 3 3 0 Cytochrome c3 Myb_DNA-bind_4 PF13837.1 CCH61436.1 - 2.8e-05 24.1 1.8 8.7e-05 22.5 0.1 2.6 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH61436.1 - 0.051 13.6 1.6 0.14 12.2 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Methyltransf_26 PF13659.1 CCH61437.1 - 3.6e-11 43.1 0.0 5.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH61437.1 - 7.6e-11 41.8 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH61437.1 - 1.3e-07 31.8 0.0 2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH61437.1 - 3.4e-06 27.6 0.0 5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH61437.1 - 4.1e-06 26.2 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.11 CCH61437.1 - 2e-05 23.8 0.1 5.3e-05 22.4 0.0 1.7 1 1 1 2 2 2 1 N-6 DNA Methylase Cons_hypoth95 PF03602.10 CCH61437.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 AviRa PF11599.3 CCH61437.1 - 0.001 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_23 PF13489.1 CCH61437.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCH61437.1 - 0.0036 16.4 0.0 0.005 16.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.7 CCH61437.1 - 0.0051 16.0 0.1 0.0097 15.0 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF890) TRM PF02005.11 CCH61437.1 - 0.0068 15.3 0.0 0.0081 15.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_16 PF10294.4 CCH61437.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 CCH61437.1 - 0.035 14.6 0.0 0.069 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCH61437.1 - 0.048 14.1 0.0 0.08 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CCH61437.1 - 0.065 12.8 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_15 PF09445.5 CCH61437.1 - 0.097 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Gcd10p PF04189.8 CCH61438.1 - 7.5e-88 294.5 11.0 1.2e-87 293.7 7.6 1.3 1 0 0 1 1 1 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 CCH61439.1 - 3e-107 358.2 0.1 5.3e-107 357.3 0.0 1.5 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CCH61439.1 - 0.00097 18.7 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCH61439.1 - 0.0015 18.5 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Actin PF00022.14 CCH61440.1 - 1.8e-51 174.8 0.0 7.4e-31 106.9 0.0 2.3 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCH61440.1 - 0.067 11.7 0.0 0.57 8.7 0.0 2.5 4 0 0 4 4 4 0 MreB/Mbl protein Ras PF00071.17 CCH61441.1 - 2.2e-57 192.9 0.1 2.7e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH61441.1 - 7e-18 65.2 0.0 4.1e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCH61441.1 - 1.7e-09 37.1 0.0 2.6e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCH61441.1 - 0.00081 18.8 0.2 0.008 15.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCH61441.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCH61441.1 - 0.0032 16.6 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCH61441.1 - 0.0034 16.6 0.0 0.006 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCH61441.1 - 0.0053 15.4 0.0 0.0059 15.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.22 CCH61441.1 - 0.042 14.1 0.2 0.084 13.1 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 CCH61441.1 - 0.054 13.1 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Y_phosphatase2 PF03162.8 CCH61443.1 - 1.2e-51 174.3 0.0 1.4e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCH61443.1 - 4.1e-06 27.1 0.0 6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Sua5_yciO_yrdC PF01300.13 CCH61445.1 - 3.1e-49 166.6 0.0 5.3e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CCH61445.1 - 5.9e-33 113.6 0.0 9.5e-33 112.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding RNA_pol_Rpb2_6 PF00562.23 CCH61446.1 - 5.9e-116 387.3 0.0 9e-116 386.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCH61446.1 - 4.4e-49 166.1 0.1 6.3e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCH61446.1 - 5.7e-34 117.2 0.0 1.1e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 CCH61446.1 - 4.9e-24 83.8 1.0 6.1e-23 80.3 0.0 3.4 5 0 0 5 5 5 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CCH61446.1 - 1.6e-23 82.3 0.0 3.5e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CCH61446.1 - 3.6e-16 59.1 0.0 4.7e-15 55.5 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CCH61446.1 - 1.5e-05 24.8 0.1 3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 B12D PF06522.6 CCH61447.1 - 0.0027 17.3 0.0 0.003 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit zf-C2H2 PF00096.21 CCH61448.1 - 1.2e-09 37.9 10.5 0.00013 22.0 1.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH61448.1 - 3.1e-05 24.0 8.2 0.0036 17.5 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH61448.1 - 0.00023 21.2 12.5 0.0012 19.0 0.4 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CCH61448.1 - 0.0042 17.2 0.5 0.0042 17.2 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CCH61448.1 - 0.14 12.4 9.6 2.9 8.3 0.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain CAF1A PF12253.3 CCH61450.1 - 2.7e-23 81.8 10.7 2.7e-23 81.8 7.4 2.7 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CCH61450.1 - 1.3e-11 44.3 69.1 1.3e-11 44.3 47.9 2.5 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MCM PF00493.18 CCH61451.1 - 9.5e-140 465.0 0.1 1.5e-139 464.4 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCH61451.1 - 8.6e-25 87.5 3.9 1.4e-24 86.8 1.1 2.7 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCH61451.1 - 1.6e-05 24.2 0.0 0.00064 18.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCH61451.1 - 2.8e-05 23.8 0.0 7.7e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCH61451.1 - 0.0012 18.4 0.0 0.014 14.9 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCH61451.1 - 0.081 12.4 0.1 4 6.8 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Bud13 PF09736.4 CCH61452.1 - 5.2e-28 98.1 1.6 5.2e-28 98.1 1.1 3.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Mannosyl_trans3 PF11051.3 CCH61454.1 - 2.2e-60 204.3 1.1 4.5e-60 203.3 0.8 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative DUF1947 PF09183.5 CCH61454.1 - 0.032 14.0 2.9 3.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Rpp20 PF12328.3 CCH61455.1 - 2.1e-19 69.6 1.3 4.3e-18 65.3 0.9 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CCH61455.1 - 1.9e-10 40.1 0.1 3.5e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Alba Transketolase_C PF02780.15 CCH61455.1 - 0.0028 17.5 0.0 0.0053 16.6 0.0 1.5 1 1 0 1 1 1 1 Transketolase, C-terminal domain LINES_N PF14694.1 CCH61455.1 - 0.022 14.0 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Lines N-terminus PDH PF02153.12 CCH61456.1 - 1.6e-09 37.0 0.0 2.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.14 CCH61456.1 - 0.00039 19.6 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CCH61456.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 CCH61456.1 - 0.0041 16.5 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CCH61456.1 - 0.0042 16.7 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCH61456.1 - 0.0077 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 CCH61456.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CCH61456.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Arf PF00025.16 CCH61457.1 - 4.5e-76 253.9 0.2 5.1e-76 253.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCH61457.1 - 1.2e-11 44.2 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCH61457.1 - 3.5e-11 42.6 0.0 4.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCH61457.1 - 9.8e-11 40.9 0.8 9.1e-07 27.8 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCH61457.1 - 2.5e-10 39.8 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCH61457.1 - 3.1e-10 40.6 0.0 4.2e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCH61457.1 - 8.9e-06 25.2 0.3 0.00016 21.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCH61457.1 - 0.00018 21.4 0.1 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCH61457.1 - 0.0008 19.7 0.9 0.0033 17.7 0.6 1.8 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 CCH61457.1 - 0.0013 17.5 1.1 0.13 11.0 0.3 2.9 2 1 0 2 2 2 1 ArgK protein cobW PF02492.14 CCH61457.1 - 0.13 11.6 0.5 4.8 6.5 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 CCH61457.1 - 0.13 11.6 0.4 0.55 9.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 2-Hacid_dh_C PF02826.14 CCH61459.1 - 4.8e-36 123.5 0.0 7.4e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCH61459.1 - 2.7e-05 23.6 0.0 3.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Glyco_trans_1_4 PF13692.1 CCH61459.1 - 0.0038 17.3 0.0 0.062 13.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 NAD_binding_7 PF13241.1 CCH61459.1 - 0.086 13.1 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCH61459.1 - 0.11 12.6 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 CCH61459.1 - 0.14 11.9 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 ThiF family NAD_binding_2 PF03446.10 CCH61459.1 - 0.19 11.5 0.0 0.45 10.3 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase TFIIA PF03153.8 CCH61460.1 - 4.5e-57 194.6 25.8 1.4e-33 117.3 13.1 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.8 CCH61460.1 - 1.3 7.4 6.5 1.8 6.9 4.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PBP1_TM PF14812.1 CCH61460.1 - 4.2 7.7 12.1 2.9 8.2 0.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec62 PF03839.11 CCH61460.1 - 8.4 5.7 10.3 4.4 6.6 5.0 1.5 1 1 0 1 1 1 0 Translocation protein Sec62 Kinetocho_Slk19 PF12709.2 CCH61461.1 - 4.3e-11 42.7 3.5 4.3e-11 42.7 2.4 9.8 1 1 7 9 9 9 2 Central kinetochore-associated RhoGAP PF00620.22 CCH61462.1 - 9e-32 109.7 0.4 9e-32 109.7 0.3 2.3 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 CCH61462.1 - 2.7e-07 30.7 1.2 1e-06 28.8 0.0 2.8 2 0 0 2 2 2 1 PH domain PX PF00787.19 CCH61462.1 - 1.1e-05 25.2 0.1 9.6e-05 22.1 0.0 2.7 3 0 0 3 3 3 1 PX domain Hist_deacetyl PF00850.14 CCH61463.1 - 5.1e-65 219.8 0.1 1e-64 218.8 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Spt5_N PF11942.3 CCH61463.1 - 1.5 9.4 16.3 0.19 12.3 7.4 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF342 PF03961.8 CCH61464.1 - 0.00027 19.4 16.4 0.00027 19.4 11.4 4.0 1 1 2 3 3 3 1 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 CCH61464.1 - 0.3 10.8 30.9 1 9.1 2.5 5.2 2 1 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CCH61464.1 - 7.1 6.9 29.3 0.13 12.4 1.5 5.2 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.24 CCH61465.1 - 1.9e-45 154.4 0.0 5.5e-45 152.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61465.1 - 6e-27 93.3 0.9 4.6e-26 90.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCH61465.1 - 0.0093 15.0 0.0 0.04 12.9 0.0 2.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit APG6 PF04111.7 CCH61466.1 - 1.1e-91 307.1 23.7 1.5e-75 254.1 14.6 4.0 2 1 1 4 4 4 2 Autophagy protein Apg6 PH_9 PF15410.1 CCH61466.1 - 0.0035 17.4 0.1 0.012 15.7 0.1 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Noc2 PF03715.8 CCH61467.1 - 1.5e-81 273.5 13.3 1.5e-81 273.5 9.2 1.8 2 0 0 2 2 2 1 Noc2p family Mei5 PF10376.4 CCH61468.1 - 1.5e-33 116.2 25.7 2.2e-33 115.6 17.6 1.4 1 1 0 1 1 1 1 Double-strand recombination repair protein CEP19 PF14933.1 CCH61468.1 - 0.1 12.8 9.3 0.13 12.5 5.9 1.6 1 1 0 1 1 1 0 CEP19-like protein Tox-REase-9 PF15650.1 CCH61468.1 - 0.63 10.2 7.7 0.24 11.5 2.6 2.2 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 9 DUF2968 PF11180.3 CCH61468.1 - 0.94 8.8 10.4 1.7 7.9 1.2 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF2968) Tfb2 PF03849.9 CCH61469.1 - 1.2e-154 514.3 5.7 1.2e-154 514.3 4.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CCH61469.1 - 2.7e-06 27.1 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HTH_45 PF14947.1 CCH61469.1 - 0.05 13.4 1.3 0.22 11.3 0.1 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix SPX PF03105.14 CCH61470.1 - 2e-08 34.3 15.9 5.4e-08 32.9 1.7 5.7 2 2 2 4 4 4 2 SPX domain Rad4 PF03835.10 CCH61471.1 - 9.1e-30 102.9 2.4 9.1e-30 102.9 1.6 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CCH61471.1 - 4.4e-22 77.5 0.0 1.1e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CCH61471.1 - 2.3e-15 55.8 0.4 1.1e-14 53.6 0.0 2.5 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCH61471.1 - 1.2e-11 44.7 0.1 1.2e-11 44.7 0.1 3.2 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CCH61471.1 - 4.6e-06 26.8 0.0 1.4e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily ChaC PF04752.7 CCH61472.1 - 7.3e-46 156.3 0.0 9.5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein E1-E2_ATPase PF00122.15 CCH61473.1 - 5.7e-16 58.2 0.0 1.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCH61473.1 - 1.4e-13 51.4 0.0 3.2e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH61473.1 - 2.2e-13 49.9 0.0 5.9e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CCH61473.1 - 7e-10 39.6 0.1 0.012 16.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCH61473.1 - 0.0042 16.7 0.2 0.0042 16.7 0.1 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PolyA_pol PF01743.15 CCH61474.1 - 5.4e-31 107.4 0.1 8.8e-31 106.7 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CCH61474.1 - 4.7e-07 29.2 0.0 1.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 CCH61474.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative zf-H2C2_2 PF13465.1 CCH61475.1 - 1.9e-05 24.7 7.0 1.9e-05 24.7 4.9 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCH61475.1 - 0.00026 21.1 18.0 0.0027 17.9 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH61475.1 - 0.00096 19.3 20.3 0.0045 17.2 2.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CCH61475.1 - 0.11 12.6 0.3 0.11 12.6 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING_3 PF14369.1 CCH61475.1 - 0.23 11.4 6.4 0.72 9.8 4.4 1.9 1 1 0 1 1 1 0 zinc-finger zf-C2H2_jaz PF12171.3 CCH61475.1 - 2.4 8.4 11.6 9.5 6.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCH61476.1 - 5.2e-07 29.6 5.8 5.2e-07 29.6 4.1 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCH61476.1 - 2.2e-06 27.6 14.4 0.0003 20.9 0.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH61476.1 - 3e-06 27.2 22.4 0.00015 21.8 1.8 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCH61476.1 - 0.0033 17.5 7.9 0.11 12.6 2.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 CCH61476.1 - 0.052 13.5 2.7 0.17 11.9 1.8 1.9 1 1 0 1 1 1 0 zinc-finger zf-met PF12874.2 CCH61476.1 - 2.6 8.3 7.4 5.3 7.3 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCH61476.1 - 2.8 7.9 9.6 11 6.0 2.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1227 PF06777.6 CCH61477.1 - 3e-58 195.6 1.2 8.2e-58 194.2 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CCH61477.1 - 1.1e-52 177.8 4.6 2e-52 177.0 3.2 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCH61477.1 - 1.4e-45 155.2 0.0 6.7e-45 153.0 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CCH61477.1 - 0.0011 18.5 0.1 0.41 10.1 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.18 CCH61477.1 - 0.0062 15.3 0.5 0.38 9.5 0.1 2.7 2 1 1 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.10 CCH61477.1 - 0.1 12.4 3.3 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Sec63 PF02889.11 CCH61478.1 - 3.6e-160 532.3 18.2 2.3e-85 286.5 1.5 2.7 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 CCH61478.1 - 4.5e-38 130.3 0.0 9.9e-27 93.4 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61478.1 - 1.1e-09 38.0 0.0 1.2e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCH61478.1 - 0.0058 16.7 0.2 0.2 11.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 CCH61479.1 - 3.7e-97 326.1 9.7 5.2e-67 226.6 2.4 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCH61479.1 - 0.032 15.0 2.4 1 10.2 0.0 3.6 2 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 CCH61479.1 - 0.035 13.6 0.1 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CCH61479.1 - 0.037 14.0 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 CCH61479.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_12 PF13087.1 CCH61480.1 - 2.4e-57 193.5 0.2 2.4e-57 193.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCH61480.1 - 4.1e-43 147.6 0.1 4.1e-43 147.6 0.1 4.8 3 1 1 4 4 3 1 AAA domain AAA_19 PF13245.1 CCH61480.1 - 3e-10 39.6 0.0 6.9e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCH61480.1 - 3e-09 36.7 0.0 3.3e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CCH61480.1 - 3.2e-06 27.3 0.6 0.00036 20.7 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCH61480.1 - 7.9e-06 25.5 5.5 0.49 9.8 0.0 5.1 5 0 0 5 5 5 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CCH61480.1 - 6.9e-05 22.9 0.0 0.00031 20.8 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.24 CCH61480.1 - 8.7e-05 22.0 0.1 0.00034 20.1 0.1 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_26 PF13500.1 CCH61480.1 - 0.00052 19.6 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CCH61480.1 - 0.00058 19.1 0.0 0.0041 16.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF3375 PF11855.3 CCH61480.1 - 0.007 15.1 0.6 0.012 14.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3375) AAA_22 PF13401.1 CCH61480.1 - 0.03 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCH61480.1 - 0.04 13.9 0.0 0.092 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ParA PF10609.4 CCH61480.1 - 0.1 12.5 2.2 8.3 6.3 0.0 3.0 2 0 0 2 2 2 0 ParA/MinD ATPase like 14-3-3 PF00244.15 CCH61482.1 - 1.2e-113 378.0 4.7 1.4e-113 377.7 3.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 CCH61482.1 - 0.34 9.9 6.3 0.045 12.9 0.3 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) COPI_assoc PF08507.5 CCH61483.1 - 2.7e-28 98.3 9.2 3.2e-28 98.1 6.4 1.0 1 0 0 1 1 1 1 COPI associated protein ALMT PF11744.3 CCH61483.1 - 0.4 9.2 2.2 0.49 8.9 1.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_M24 PF00557.19 CCH61484.1 - 3.1e-08 33.4 0.0 6.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Ste5_C PF12194.3 CCH61485.1 - 3.5e-57 193.1 3.2 3.5e-57 193.1 2.2 2.0 2 0 0 2 2 2 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 CCH61485.1 - 2.9e-05 23.8 5.2 5.5e-05 22.9 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH61485.1 - 0.33 10.9 7.1 0.84 9.7 4.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH61485.1 - 0.34 10.5 6.7 0.86 9.3 4.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH61485.1 - 0.55 10.0 4.0 1.4 8.7 2.8 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Actin PF00022.14 CCH61486.1 - 4.5e-12 45.1 0.0 2e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Actin DUF2205 PF10224.4 CCH61488.1 - 1.1e-07 31.3 1.0 1.2e-07 31.2 0.7 1.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Integrase_DNA PF02920.10 CCH61488.1 - 0.032 13.6 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase DUF3350 PF11830.3 CCH61488.1 - 0.043 13.8 0.9 0.054 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) Dna2 PF08696.6 CCH61488.1 - 0.046 13.0 0.1 0.05 12.9 0.1 1.0 1 0 0 1 1 1 0 DNA replication factor Dna2 DUP PF00674.13 CCH61489.1 - 2.6e-19 69.1 0.7 2.6e-19 69.1 0.5 2.0 1 1 2 3 3 3 1 DUP family DUP PF00674.13 CCH61490.1 - 2.4e-16 59.6 0.8 6.4e-16 58.2 0.1 1.8 1 1 1 2 2 2 1 DUP family MA-Mit PF09245.5 CCH61490.1 - 0.053 12.7 0.1 0.087 12.0 0.1 1.3 1 0 0 1 1 1 0 Mycoplasma arthritidis-derived mitogen EMP70 PF02990.11 CCH61491.1 - 2.4e-194 646.6 15.1 3.4e-194 646.1 10.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_B PF00430.13 CCH61491.1 - 0.49 10.1 0.9 1.1 9.0 0.6 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TRAPPC-Trs85 PF12739.2 CCH61492.1 - 2.8e-93 312.8 3.7 5.2e-93 311.9 2.5 1.4 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Rax2 PF12768.2 CCH61493.1 - 1.7e-50 171.7 10.5 1.7e-50 171.7 7.3 5.4 4 1 0 5 5 5 2 Cortical protein marker for cell polarity Herpes_US9 PF06072.6 CCH61493.1 - 0.17 11.7 0.3 0.32 10.8 0.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 FGGY_C PF02782.11 CCH61494.1 - 2.9e-47 160.8 0.0 4.3e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCH61494.1 - 4.1e-22 78.6 0.2 6.8e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 CCH61494.1 - 0.0019 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DNA_pol_A_exo1 PF01612.15 CCH61494.1 - 0.094 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease SMC_N PF02463.14 CCH61495.1 - 2.8e-58 196.7 84.0 4.4e-31 107.8 23.6 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCH61495.1 - 7.4e-26 90.4 0.0 3.2e-25 88.4 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCH61495.1 - 1.3e-09 38.4 15.3 6e-06 26.4 0.3 6.3 2 2 4 6 6 6 2 AAA domain AAA_29 PF13555.1 CCH61495.1 - 9.3e-06 25.0 0.0 3.2e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Myosin_tail_1 PF01576.14 CCH61495.1 - 0.00077 17.3 59.8 0.00077 17.3 41.5 3.9 2 2 0 2 2 2 1 Myosin tail Aminotran_1_2 PF00155.16 CCH61498.1 - 3.2e-38 131.6 0.0 4.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCH61498.1 - 0.041 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2407_C PF13373.1 CCH61499.1 - 1.4 8.8 8.0 0.33 10.8 2.5 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain DUF4592 PF15262.1 CCH61499.1 - 3 8.4 8.7 0.1 13.1 1.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4592) Ribosomal_L34 PF00468.12 CCH61500.1 - 4.1e-17 61.5 5.3 4.1e-17 61.5 3.7 1.5 1 1 1 2 2 2 1 Ribosomal protein L34 PP-binding PF00550.20 CCH61502.1 - 1.1e-10 41.5 0.6 1.8e-10 40.9 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CCH61502.1 - 3e-07 30.3 1.4 6.7e-07 29.2 0.8 1.7 2 1 0 2 2 2 1 Acyl-carrier DUF1493 PF07377.7 CCH61502.1 - 0.0037 17.3 0.8 0.0057 16.7 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1493) AMA-1 PF02430.10 CCH61502.1 - 0.034 13.0 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 LRR_4 PF12799.2 CCH61503.1 - 7.4e-39 130.7 43.4 9.4e-11 41.0 2.6 7.4 4 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH61503.1 - 1.9e-28 98.0 57.1 1.2e-09 37.7 0.6 5.6 1 1 7 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 CCH61503.1 - 2.7e-13 47.9 38.6 0.087 12.9 0.2 11.7 11 1 1 12 12 12 6 Leucine Rich Repeat LRR_6 PF13516.1 CCH61503.1 - 1.3e-09 37.0 31.0 0.14 12.2 0.0 10.6 9 2 3 12 12 12 4 Leucine Rich repeat LRR_9 PF14580.1 CCH61503.1 - 9.6e-09 35.0 17.6 0.0077 15.8 2.3 4.2 1 1 5 6 6 6 6 Leucine-rich repeat LRR_7 PF13504.1 CCH61503.1 - 1.9e-07 30.1 18.2 1 9.8 0.0 9.6 7 3 1 8 8 8 2 Leucine rich repeat DUF3744 PF12558.3 CCH61503.1 - 0.61 10.5 15.4 0.35 11.3 1.8 4.1 3 2 1 4 4 4 0 ATP-binding cassette cobalt transporter tRNA-synt_2b PF00587.20 CCH61504.1 - 4.2e-47 159.9 0.1 6.5e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH61504.1 - 4.4e-16 58.6 0.1 8e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.7 CCH61505.1 - 5e-88 295.6 28.1 5.6e-88 295.4 19.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 NFRKB_winged PF14465.1 CCH61505.1 - 0.32 10.8 2.7 4.9 7.0 0.1 3.0 1 1 1 2 2 2 0 NFRKB Winged Helix-like DUF1664 PF07889.7 CCH61505.1 - 1.2 8.9 20.9 0.75 9.6 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) RST PF12174.3 CCH61505.1 - 7 6.5 7.6 17 5.3 0.9 3.3 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Ima1_N PF09779.4 CCH61505.1 - 8.1 6.9 7.5 4 7.9 0.2 3.0 3 0 0 3 3 3 0 Ima1 N-terminal domain G-patch PF01585.18 CCH61506.1 - 2e-10 40.2 3.6 5e-10 39.0 2.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCH61506.1 - 0.0011 18.8 0.9 0.0011 18.8 0.6 2.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site CNH PF00780.17 CCH61507.1 - 5.5e-17 62.0 0.2 2.5e-16 59.9 0.1 2.2 2 1 0 2 2 2 1 CNH domain PH_5 PF15405.1 CCH61507.1 - 3.3e-07 30.3 0.1 3.3e-07 30.3 0.0 4.7 5 0 0 5 5 5 1 Pleckstrin homology domain zf-RING_5 PF14634.1 CCH61508.1 - 5.3e-07 29.2 5.5 1.2e-06 28.1 3.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCH61508.1 - 4.4e-06 26.4 5.3 8.5e-06 25.5 3.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH61508.1 - 1e-05 25.4 7.0 2.2e-05 24.3 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH61508.1 - 1.6e-05 24.4 6.7 4e-05 23.1 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH61508.1 - 3.7e-05 23.3 4.1 6.6e-05 22.4 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH61508.1 - 0.00047 19.8 3.0 0.0013 18.3 2.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCH61508.1 - 0.00057 19.7 7.4 0.0019 18.0 5.2 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1676 PF07898.8 CCH61508.1 - 0.011 15.9 2.5 0.029 14.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) TerY-C PF15616.1 CCH61508.1 - 3.6 7.5 15.5 2.5 8.0 0.1 4.2 5 1 1 6 6 6 0 TerY-C metal binding domain DUF1900 PF08954.6 CCH61509.1 - 1.8e-42 144.1 0.0 3.7e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCH61509.1 - 8.6e-25 86.1 0.1 1.8e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCH61509.1 - 2.6e-24 84.1 5.0 2.7e-07 30.2 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat V-SNARE PF05008.10 CCH61509.1 - 0.025 14.7 1.7 0.043 13.9 1.2 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus IMPDH PF00478.20 CCH61511.1 - 4.4e-141 469.8 2.5 5.2e-141 469.6 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CCH61511.1 - 4.9e-16 58.2 0.0 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CCH61511.1 - 2.8e-08 33.2 2.2 3.2e-05 23.2 1.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CCH61511.1 - 5.2e-07 28.8 2.2 1.5e-06 27.3 1.4 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCH61511.1 - 2.7e-05 23.5 2.2 0.00028 20.2 1.4 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 CCH61511.1 - 0.0015 17.7 0.8 0.0085 15.2 0.1 2.2 2 0 0 2 2 2 1 KDPG and KHG aldolase NanE PF04131.9 CCH61511.1 - 0.0046 15.9 0.4 0.0097 14.8 0.3 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FIST PF08495.5 CCH61511.1 - 0.0064 15.6 0.3 0.021 13.9 0.2 1.7 1 1 0 1 1 1 1 FIST N domain PK PF00224.16 CCH61511.1 - 0.016 13.8 0.2 0.66 8.5 0.0 2.6 3 0 0 3 3 3 0 Pyruvate kinase, barrel domain Response_reg PF00072.19 CCH61511.1 - 0.028 14.4 0.2 0.12 12.3 0.1 2.1 1 1 0 1 1 1 0 Response regulator receiver domain DUF1273 PF06908.6 CCH61511.1 - 0.081 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) ThiG PF05690.9 CCH61511.1 - 0.13 11.3 3.0 0.14 11.2 0.7 1.9 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Metallophos PF00149.23 CCH61512.1 - 1.6e-41 141.8 0.9 2.7e-41 141.2 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Hid1 PF12722.2 CCH61513.1 - 2e-169 565.2 123.3 1.4e-166 555.7 85.5 2.1 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein cNMP_binding PF00027.24 CCH61514.1 - 6.5e-40 134.8 1.5 7.7e-17 60.8 0.0 5.3 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CCH61514.1 - 7.1e-18 65.2 3.9 1.1e-15 58.1 2.0 3.3 2 1 0 2 2 2 1 Patatin-like phospholipase LSM PF01423.17 CCH61515.1 - 7.7e-17 60.6 0.1 9.3e-17 60.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCH61515.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain MRP-L47 PF06984.8 CCH61516.1 - 2.4e-23 81.8 0.5 2.4e-23 81.8 0.3 2.1 3 0 0 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) OGG_N PF07934.7 CCH61517.1 - 3.7e-19 68.8 1.8 7.5e-19 67.8 1.2 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CCH61517.1 - 6.1e-15 55.4 0.0 2.5e-14 53.4 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIF1 PF05970.9 CCH61518.1 - 1.7e-72 244.3 1.9 6.7e-54 183.2 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CCH61518.1 - 2.9e-10 40.0 0.0 5.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH61518.1 - 7.4e-07 29.3 0.1 2.5e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 CCH61518.1 - 0.0012 18.9 0.0 0.0049 16.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCH61518.1 - 0.0015 18.2 0.1 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_32 PF13654.1 CCH61518.1 - 0.0029 16.3 0.8 0.008 14.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCH61518.1 - 0.0045 16.1 0.0 0.0098 15.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 CCH61518.1 - 0.023 13.6 0.0 0.052 12.4 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CCH61518.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 CCH61518.1 - 0.044 13.0 0.0 0.14 11.3 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 CCH61518.1 - 0.059 13.0 0.1 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Helicase_RecD PF05127.9 CCH61518.1 - 0.16 11.6 2.2 0.24 10.9 0.1 2.5 2 1 0 2 2 2 0 Helicase THOC7 PF05615.8 CCH61519.1 - 1.9e-14 54.1 10.6 1.9e-14 54.1 7.4 2.8 2 1 0 2 2 2 1 Tho complex subunit 7 Myb_DNA-bind_3 PF12776.2 CCH61519.1 - 0.028 15.0 0.8 0.028 15.0 0.6 3.9 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF479 PF04336.7 CCH61519.1 - 0.22 11.6 2.8 1.2 9.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF479 bZIP_1 PF00170.16 CCH61519.1 - 4.3 7.3 13.0 1.2 9.1 0.3 4.0 3 1 0 4 4 4 0 bZIP transcription factor Ribosomal_S3Ae PF01015.13 CCH61520.1 - 8.3e-80 266.7 7.1 9.8e-80 266.4 4.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 CCH61520.1 - 0.026 13.8 0.0 0.084 12.2 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region AAA PF00004.24 CCH61521.1 - 1.5e-19 70.5 0.0 1.8e-18 67.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCH61521.1 - 4.1e-07 30.1 0.0 5.9e-05 23.1 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCH61521.1 - 1e-06 28.8 0.4 5.6e-06 26.5 0.0 2.4 4 0 0 4 4 4 1 AAA domain BAH PF01426.13 CCH61521.1 - 2.4e-06 27.2 0.1 5.1e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 BAH domain NACHT PF05729.7 CCH61521.1 - 0.0023 17.5 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 CCH61521.1 - 0.0062 17.3 0.3 0.048 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain Katanin_con80 PF13925.1 CCH61521.1 - 0.11 12.1 4.9 3.3 7.4 0.0 3.0 3 0 0 3 3 3 0 con80 domain of Katanin AAA_19 PF13245.1 CCH61521.1 - 0.21 11.3 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2206 PF09971.4 CCH61522.1 - 0.9 8.2 4.2 2.4 6.8 2.9 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2206) Dor1 PF04124.7 CCH61523.1 - 2.2e-42 144.7 7.0 3.9e-42 143.9 4.8 1.3 1 0 0 1 1 1 1 Dor1-like family C2 PF00168.25 CCH61524.1 - 1.4e-47 159.4 1.2 2.7e-18 65.5 0.0 5.6 5 0 0 5 5 5 4 C2 domain Piwi PF02171.12 CCH61525.1 - 8.1e-63 212.1 0.4 1.3e-62 211.5 0.3 1.3 1 0 0 1 1 1 1 Piwi domain CDC27 PF09507.5 CCH61525.1 - 0.7 9.0 93.7 1.6 7.8 65.0 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HMG-CoA_red PF00368.13 CCH61526.1 - 8e-157 521.6 0.1 1.2e-156 521.1 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 CCH61526.1 - 1.4e-30 106.0 3.8 1.4e-30 106.0 0.1 2.6 2 1 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 CCH61526.1 - 5.5e-07 29.1 6.2 5.5e-07 29.1 4.3 1.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Zn_clus PF00172.13 CCH61527.1 - 6.3e-07 29.1 8.1 1.5e-06 28.0 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ENTH PF01417.15 CCH61528.1 - 3.5e-42 143.1 0.0 7e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCH61528.1 - 0.00015 20.5 0.0 0.00031 19.5 0.0 1.5 1 0 0 1 1 1 1 ANTH domain DUF773 PF05600.7 CCH61528.1 - 2.7 6.6 9.0 2.2 6.9 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF773) zf-H2C2_2 PF13465.1 CCH61529.1 - 2e-06 27.8 8.2 2.3e-05 24.4 2.7 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCH61529.1 - 2.2e-05 24.5 16.4 0.00049 20.2 1.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH61529.1 - 0.0061 16.8 2.6 0.0061 16.8 1.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger ATP-synt_J PF04911.7 CCH61530.1 - 1.5e-20 72.3 0.3 1.7e-20 72.2 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.15 CCH61531.1 - 0.00014 20.2 0.1 0.0019 16.5 0.1 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Ctf8 PF09696.5 CCH61532.1 - 1.4e-24 86.2 0.1 2e-24 85.7 0.1 1.2 1 0 0 1 1 1 1 Ctf8 DNA_ligase_IV PF11411.3 CCH61532.1 - 0.024 14.3 0.1 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV Pox_I6 PF04595.8 CCH61532.1 - 0.061 12.0 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family DUF2296 PF10058.4 CCH61533.1 - 4.1e-11 42.4 1.8 6.4e-11 41.8 1.3 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2207 PF09972.4 CCH61533.1 - 0.0086 14.7 2.2 0.0086 14.7 1.5 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) Vps23_core PF09454.5 CCH61533.1 - 0.022 14.3 0.2 0.15 11.6 0.1 2.1 2 0 0 2 2 2 0 Vps23 core domain DUF996 PF06195.8 CCH61533.1 - 0.033 14.1 1.7 0.049 13.6 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Prefoldin PF02996.12 CCH61533.1 - 0.033 13.8 7.8 0.41 10.3 2.6 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF1426 PF07234.6 CCH61533.1 - 0.091 12.4 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) SlyX PF04102.7 CCH61533.1 - 0.1 12.9 3.0 0.2 12.0 0.9 2.1 2 0 0 2 2 2 0 SlyX zf-Sec23_Sec24 PF04810.10 CCH61533.1 - 0.19 11.2 2.9 0.36 10.4 2.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger DUF1664 PF07889.7 CCH61533.1 - 1.4 8.7 3.9 28 4.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-Q PF13094.1 CCH61533.1 - 1.7 8.6 8.7 0.3 11.0 0.4 2.4 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3847 PF12958.2 CCH61533.1 - 4.3 7.1 11.3 7.5 6.3 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Lge1 PF11488.3 CCH61533.1 - 4.4 7.5 8.0 8.2 6.6 2.3 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 NAC PF01849.13 CCH61534.1 - 9.5e-21 73.0 0.3 1.7e-20 72.2 0.2 1.4 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CCH61534.1 - 9.3e-06 25.3 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain IMS_HHH PF11798.3 CCH61534.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 IMS family HHH motif IBN_N PF03810.14 CCH61535.1 - 3.4e-17 62.1 2.5 8.2e-17 60.8 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Pribosyltran PF00156.22 CCH61536.1 - 6.8e-12 45.2 0.4 5.5e-11 42.2 0.3 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DUF2031 PF09592.5 CCH61536.1 - 0.15 11.1 0.7 0.24 10.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) RIX1 PF08167.7 CCH61537.1 - 1.7e-41 141.6 6.3 1.7e-41 141.6 4.4 2.8 2 1 0 2 2 2 2 rRNA processing/ribosome biogenesis AATF-Che1 PF13339.1 CCH61537.1 - 1.1 9.3 9.6 0.24 11.5 1.1 2.9 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF3608 PF12257.3 CCH61538.1 - 5.4e-128 425.7 5.1 5.4e-128 425.7 3.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3608) DEP PF00610.16 CCH61538.1 - 7.2e-25 86.5 0.5 1.9e-24 85.1 0.3 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.14 CCH61539.1 - 1e-53 181.6 0.0 1.4e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CCH61539.1 - 8e-20 71.3 0.0 1.4e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1889 PF08986.5 CCH61539.1 - 0.059 13.5 0.0 5.1 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) Hydrolase_6 PF13344.1 CCH61539.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HECT_2 PF09814.4 CCH61541.1 - 2.4e-65 220.5 0.7 2.8e-65 220.3 0.5 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-P11 PF03854.9 CCH61541.1 - 0.13 11.7 2.4 0.16 11.4 0.2 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-BED PF02892.10 CCH61541.1 - 0.61 9.8 4.5 2.4 7.9 0.3 2.6 2 0 0 2 2 2 0 BED zinc finger DHHA2 PF02833.9 CCH61542.1 - 8.1e-22 77.7 1.1 1.3e-21 77.1 0.7 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CCH61542.1 - 5.2e-10 39.1 0.6 2.6e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 DHH family Metallophos PF00149.23 CCH61543.1 - 2.7e-09 36.7 9.6 8.6e-09 35.0 6.6 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S4e PF00900.15 CCH61544.1 - 7.9e-33 111.9 2.1 1.7e-31 107.7 0.8 2.2 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CCH61544.1 - 1.2e-19 69.8 4.9 2.6e-19 68.7 3.4 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CCH61544.1 - 1.4e-08 34.0 0.1 3.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CCH61544.1 - 1.1e-05 24.8 1.5 1.1e-05 24.8 1.0 3.7 4 0 0 4 4 4 1 KOW motif Glyco_hydro_47 PF01532.15 CCH61545.1 - 4.5e-117 391.4 0.6 6.1e-117 391.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 CCH61546.1 - 2.2e-60 204.0 0.0 3.3e-60 203.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61546.1 - 2.5e-31 108.6 0.0 3.6e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61546.1 - 0.052 12.5 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CCH61546.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.12 CCH61547.1 - 3.2e-30 104.3 4.2 3.2e-30 104.3 2.9 2.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 CCH61547.1 - 1.5e-11 44.2 0.2 7.7e-11 42.0 0.1 2.3 3 0 0 3 3 3 1 Response regulator receiver domain SET PF00856.23 CCH61548.1 - 1.8e-08 34.8 1.7 1.5e-07 31.8 1.2 2.5 1 1 0 1 1 1 1 SET domain Myticin-prepro PF10690.4 CCH61548.1 - 0.17 11.9 2.9 3 7.9 0.3 2.6 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel Aminotran_4 PF01063.14 CCH61550.1 - 6.1e-29 101.1 0.0 8e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Zn_clus PF00172.13 CCH61552.1 - 2.1e-07 30.7 8.4 4.1e-07 29.7 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 CCH61553.1 - 1.7e-60 204.2 0.0 2e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Torsin PF06309.6 CCH61553.1 - 0.11 12.3 0.2 0.84 9.5 0.1 2.1 1 1 1 2 2 2 0 Torsin EzrA PF06160.7 CCH61554.1 - 0.03 12.5 0.1 0.059 11.5 0.0 1.4 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SPOB_a PF14689.1 CCH61554.1 - 0.14 11.7 0.4 0.4 10.2 0.1 1.9 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF3533 PF12051.3 CCH61555.1 - 7.1e-93 311.3 22.3 7.1e-93 311.3 15.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) DUF2975 PF11188.3 CCH61555.1 - 0.0099 15.5 6.4 0.076 12.7 3.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) PDR_CDR PF06422.7 CCH61555.1 - 0.037 13.6 0.1 0.037 13.6 0.0 3.7 5 0 0 5 5 5 0 CDR ABC transporter tRNA-synt_2b PF00587.20 CCH61555.1 - 0.61 9.6 4.4 0.45 10.0 0.2 2.4 2 1 1 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) DUF3533 PF12051.3 CCH61557.1 - 1.1e-89 300.8 24.6 1.1e-89 300.8 17.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) DUF1322 PF07032.6 CCH61557.1 - 0.061 13.5 1.6 0.097 12.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) YjcZ PF13990.1 CCH61557.1 - 0.87 8.6 4.5 0.19 10.8 0.2 2.0 3 0 0 3 3 3 0 YjcZ-like protein PDR_CDR PF06422.7 CCH61557.1 - 2.2 7.9 6.1 0.69 9.6 0.0 2.9 3 0 0 3 3 3 0 CDR ABC transporter RRM_1 PF00076.17 CCH61558.1 - 0.0058 16.2 0.2 1.5 8.4 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NGP1NT PF08153.7 CCH61559.1 - 1.1e-48 164.4 0.1 2.2e-48 163.4 0.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CCH61559.1 - 4.2e-20 71.8 0.0 3.5e-15 55.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCH61559.1 - 2.7e-05 23.4 0.0 0.00014 21.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CCH61559.1 - 0.0011 18.1 0.1 0.21 10.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 CCH61559.1 - 0.0015 17.7 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCH61559.1 - 0.0016 17.8 0.0 0.37 10.2 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCH61559.1 - 0.0029 17.4 4.8 0.33 10.7 0.0 3.7 3 1 1 4 4 4 1 Dynamin family SusD-like_3 PF14322.1 CCH61559.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane CAF1 PF04857.15 CCH61560.1 - 6.4e-51 173.1 1.0 6.4e-51 173.1 0.7 2.2 2 0 0 2 2 2 1 CAF1 family ribonuclease Hom_end_hint PF05203.11 CCH61560.1 - 0.0061 16.3 1.0 0.0078 15.9 0.7 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Exonuc_VII_L PF02601.10 CCH61560.1 - 0.042 13.0 13.3 0.065 12.4 9.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mem_trans PF03547.13 CCH61560.1 - 0.08 11.2 1.1 0.11 10.8 0.7 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4355 PF14265.1 CCH61560.1 - 0.2 11.6 18.2 0.44 10.5 12.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Neur_chan_memb PF02932.11 CCH61560.1 - 0.93 9.3 6.1 1.4 8.7 4.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CCH61560.1 - 3.3 7.3 7.0 5.4 6.7 4.8 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.1 CCH61560.1 - 10 5.0 13.2 17 4.2 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTF2 PF02136.15 CCH61561.1 - 7.7e-17 61.7 0.9 1.9e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Y_phosphatase2 PF03162.8 CCH61562.1 - 4.3e-35 120.5 3.9 2.2e-24 85.6 0.3 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Saccharop_dh PF03435.13 CCH61563.1 - 4.1e-125 417.7 0.0 4.7e-125 417.5 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CCH61563.1 - 4.2e-08 33.3 0.1 7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCH61563.1 - 1.6e-05 25.2 0.1 3.3e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 CCH61563.1 - 0.00025 21.0 0.1 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 CCH61563.1 - 0.0024 17.2 0.1 0.0086 15.4 0.1 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain DUF2325 PF10087.4 CCH61563.1 - 0.0035 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_3 PF03447.11 CCH61563.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CCH61563.1 - 0.015 15.5 0.1 0.027 14.7 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CCH61563.1 - 0.077 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3Beta_HSD PF01073.14 CCH61563.1 - 0.091 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CCH61563.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Mso1_Sec1_bdg PF14475.1 CCH61564.1 - 1e-15 56.8 0.0 2.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 DUF605 PF04652.11 CCH61564.1 - 4.3 6.6 32.0 5.3 6.3 22.2 1.1 1 0 0 1 1 1 0 Vta1 like CDC50 PF03381.10 CCH61565.1 - 8.2e-97 323.6 5.5 1.1e-96 323.2 3.8 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Not1 PF04054.10 CCH61566.1 - 5e-134 446.9 13.9 5e-134 446.9 9.6 3.7 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CCH61566.1 - 3.7e-41 140.2 3.9 1.7e-40 138.1 2.7 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) MutS_V PF00488.16 CCH61567.1 - 4.9e-72 242.1 0.1 1.3e-71 240.7 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CCH61567.1 - 2.7e-36 125.2 1.0 2.7e-36 125.2 0.7 2.1 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CCH61567.1 - 2.2e-28 98.5 0.1 5.4e-28 97.2 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CCH61567.1 - 2.9e-13 49.8 0.7 2e-12 47.1 0.5 2.5 1 0 0 1 1 1 1 MutS family domain IV Pkinase PF00069.20 CCH61568.1 - 4.9e-73 245.4 0.1 1.2e-72 244.1 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61568.1 - 3.4e-31 108.2 0.1 1.8e-30 105.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61568.1 - 8.7e-06 24.8 0.1 0.00022 20.3 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CCH61568.1 - 0.061 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF866 PF05907.8 CCH61570.1 - 8e-24 83.9 9.9 1.1e-21 77.0 6.9 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF2203 PF09969.4 CCH61570.1 - 0.095 12.9 0.4 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) zf-C4_ClpX PF06689.8 CCH61570.1 - 0.35 10.4 3.8 0.91 9.0 0.7 2.3 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-DNL PF05180.7 CCH61570.1 - 5.3 6.8 7.8 6.1 6.6 3.4 2.5 2 1 0 2 2 2 0 DNL zinc finger Elf1 PF05129.8 CCH61570.1 - 7.6 6.3 9.7 25 4.6 0.1 3.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Flocculin_t3 PF13928.1 CCH61571.1 - 3.6e-05 23.8 53.0 0.00012 22.1 14.3 19.2 8 7 5 13 13 13 2 Flocculin type 3 repeat Myosin_N PF02736.14 CCH61571.1 - 2.1 8.1 13.1 0.4 10.3 0.4 3.8 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain Cofilin_ADF PF00241.15 CCH61572.1 - 5.7e-22 77.9 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 CCH61572.1 - 4.1e-17 61.2 0.6 1.3e-16 59.7 0.4 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH61572.1 - 5.6e-15 54.6 0.2 1.1e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH61572.1 - 1.9e-07 30.4 0.1 4.5e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Trehalase PF01204.13 CCH61573.1 - 8.2e-187 621.8 0.0 1e-186 621.5 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCH61573.1 - 2.6e-16 58.6 0.3 5.2e-16 57.6 0.2 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF77 PF01910.12 CCH61574.1 - 9.4e-29 98.9 0.0 1.1e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Histone PF00125.19 CCH61575.1 - 1.1e-21 76.7 0.3 1.5e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH61575.1 - 6.6e-06 26.0 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCH61575.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CCH61575.1 - 0.015 13.9 2.8 0.02 13.6 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RP-C PF03428.8 CCH61575.1 - 0.081 12.3 0.2 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain RNA_pol_Rpb2_1 PF04563.10 CCH61575.1 - 1 8.2 4.8 4.2 6.2 1.1 2.0 1 1 1 2 2 2 0 RNA polymerase beta subunit Histone PF00125.19 CCH61576.1 - 9.4e-26 89.7 0.0 1.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH61576.1 - 1.2e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.7 CCH61576.1 - 0.27 10.5 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Der GTPase activator (YihI) DRIM PF07539.7 CCH61577.1 - 9.4e-47 157.9 1.8 2.4e-46 156.6 0.1 2.7 2 0 0 2 2 2 1 Down-regulated in metastasis Rad21_Rec8_N PF04825.8 CCH61578.1 - 2.3e-24 85.4 0.3 5.2e-24 84.3 0.2 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCH61578.1 - 7.5e-10 37.8 0.0 1.7e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CCH61578.1 - 0.0063 16.1 0.3 0.0063 16.1 0.2 2.5 3 0 0 3 3 3 1 ScpA/B protein DUF968 PF06147.6 CCH61578.1 - 0.029 14.2 0.2 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF968) CcdB PF01845.12 CCH61578.1 - 0.086 12.7 0.2 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 CcdB protein Med2 PF11214.3 CCH61579.1 - 1.2e-15 57.3 74.0 2.6e-13 49.9 43.5 4.7 2 1 0 2 2 2 1 Mediator complex subunit 2 MIP-T3 PF10243.4 CCH61579.1 - 0.0005 18.6 44.7 0.00082 17.9 31.0 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 COX6A PF02046.10 CCH61580.1 - 2.4e-39 133.8 1.0 3e-39 133.5 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa zf-C2H2 PF00096.21 CCH61581.1 - 5.1e-12 45.3 16.3 1.3e-05 25.1 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH61581.1 - 3.4e-09 36.3 14.1 0.00019 21.5 1.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCH61581.1 - 1.6e-08 34.4 9.7 0.0012 18.9 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCH61581.1 - 1.5e-06 28.1 17.0 1.5e-05 25.0 3.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CCH61581.1 - 0.00013 21.9 9.6 0.15 12.2 2.9 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCH61581.1 - 0.00034 20.6 4.8 0.00058 19.9 3.3 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CCH61581.1 - 0.02 14.7 9.4 0.11 12.4 1.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CCH61581.1 - 0.097 12.3 8.5 0.9 9.2 1.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 CCH61581.1 - 0.12 12.5 11.1 3.4 7.8 2.0 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CCH61581.1 - 0.14 11.9 10.1 0.72 9.6 1.6 3.0 1 1 1 2 2 2 0 BED zinc finger zf-CHCC PF10276.4 CCH61581.1 - 0.43 10.4 1.9 0.63 9.9 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger domain Elf1 PF05129.8 CCH61581.1 - 1.8 8.2 5.7 6.9 6.4 0.7 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like PUF PF00806.14 CCH61582.1 - 2.6e-40 133.6 28.9 8.9e-06 24.9 0.0 8.9 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MT-A70 PF05063.9 CCH61583.1 - 4.2e-54 182.7 0.2 8.9e-54 181.6 0.2 1.6 1 0 0 1 1 1 1 MT-A70 DUF3554 PF12074.3 CCH61585.1 - 1.3e-42 146.5 28.5 1e-23 84.3 1.4 6.7 5 2 2 7 7 7 3 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 CCH61585.1 - 3.1e-40 136.3 6.6 3.8e-09 36.7 0.0 13.9 7 3 5 13 13 13 7 HEAT repeats HEAT PF02985.17 CCH61585.1 - 3.8e-33 110.5 8.0 0.004 17.1 0.0 18.5 20 0 0 20 20 20 6 HEAT repeat HEAT_EZ PF13513.1 CCH61585.1 - 1.1e-28 98.9 17.1 0.0049 17.3 1.2 16.3 13 4 5 18 18 18 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCH61585.1 - 3.7e-10 40.0 0.7 2.2 8.7 0.0 8.2 7 1 0 8 8 8 2 Vacuolar 14 Fab1-binding region QueF PF14489.1 CCH61585.1 - 0.028 14.3 0.0 0.43 10.5 0.0 3.0 2 0 0 2 2 2 0 QueF-like protein Phage_Coat_Gp8 PF05371.7 CCH61585.1 - 0.041 13.4 0.0 0.53 9.8 0.0 2.6 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Kelch_4 PF13418.1 CCH61586.1 - 1.9e-12 46.7 4.5 1.7e-06 27.6 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CCH61586.1 - 7.9e-11 41.6 1.1 1.2e-06 28.3 0.1 4.8 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 CCH61586.1 - 8e-10 38.1 1.2 0.00013 21.3 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CCH61586.1 - 5.7e-09 35.8 0.5 0.013 15.6 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CCH61586.1 - 1.4e-06 27.8 0.7 0.0065 16.2 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CCH61586.1 - 0.00059 19.7 0.0 0.0096 15.8 0.0 3.0 3 0 0 3 3 3 1 Kelch motif Yip1 PF04893.12 CCH61587.1 - 4.3e-07 29.6 8.8 5.6e-07 29.2 6.1 1.2 1 0 0 1 1 1 1 Yip1 domain Lgl_C PF08596.5 CCH61588.1 - 3.9e-118 394.3 0.8 8.9e-118 393.1 0.1 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCH61588.1 - 5.3e-05 22.9 2.4 10 6.1 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 CCH61588.1 - 0.056 11.6 0.1 0.13 10.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Actin PF00022.14 CCH61589.1 - 1.1e-49 168.8 0.5 5.9e-36 123.7 0.1 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCH61589.1 - 0.0026 16.4 0.1 0.11 11.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein IATP PF04568.7 CCH61590.1 - 7.6 6.6 8.8 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Sugar_tr PF00083.19 CCH61591.1 - 1.5e-06 27.0 6.0 1.5e-06 27.0 4.2 2.7 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CCH61591.1 - 1.2e-05 23.7 14.2 1.2e-05 23.7 9.8 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CCH61591.1 - 1.7e-05 23.7 46.1 0.00039 19.2 29.7 3.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ARD PF03079.9 CCH61591.1 - 0.03 14.2 4.5 0.069 13.0 3.2 1.5 1 0 0 1 1 1 0 ARD/ARD' family TIP41 PF04176.8 CCH61592.1 - 3.9e-70 234.7 3.8 6.3e-70 234.1 2.6 1.3 1 0 0 1 1 1 1 TIP41-like family BIR PF00653.16 CCH61593.1 - 2.5e-11 43.8 1.1 3.1e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain UbiA PF01040.13 CCH61595.1 - 1.9e-24 86.3 14.5 2.4e-24 85.9 10.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family WD40 PF00400.27 CCH61596.1 - 7.1e-65 212.7 14.0 5.5e-10 38.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCH61596.1 - 8.1e-29 99.6 12.0 7.9e-28 96.4 7.5 2.5 2 0 0 2 2 2 1 Tup N-terminal Nup160 PF11715.3 CCH61596.1 - 5.4e-05 21.5 13.9 0.039 12.1 0.1 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Trypan_PARP PF05887.6 CCH61596.1 - 0.00033 20.4 17.0 0.00059 19.6 11.8 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF3312 PF11768.3 CCH61596.1 - 0.013 13.7 0.3 0.19 9.9 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF3312) CCDC-167 PF15188.1 CCH61596.1 - 0.028 14.3 3.2 0.059 13.3 2.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 PD40 PF07676.7 CCH61596.1 - 0.043 13.4 0.1 98 2.7 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 CCH61596.1 - 0.05 13.0 4.9 0.068 12.6 2.0 2.2 1 1 1 2 2 2 0 PQQ-like domain PAT1 PF09770.4 CCH61596.1 - 0.22 9.7 51.4 0.39 8.9 35.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tsg PF04668.7 CCH61596.1 - 0.91 9.7 5.7 1.7 8.8 0.4 2.6 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Neisseria_TspB PF05616.8 CCH61596.1 - 3.5 5.9 26.7 6.7 4.9 18.5 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Csm1 PF12539.3 CCH61597.1 - 7.8e-27 93.5 1.1 9.1e-27 93.3 0.1 1.6 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF16 PF01519.11 CCH61597.1 - 0.0025 17.9 3.8 0.0025 17.9 2.6 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF16 Complex1_49kDa PF00346.14 CCH61597.1 - 0.024 13.6 0.0 0.048 12.6 0.0 1.5 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit CENP-Q PF13094.1 CCH61597.1 - 0.032 14.2 3.9 0.046 13.7 2.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.6 CCH61597.1 - 0.12 12.7 1.5 0.2 12.0 1.0 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal zf-LYAR PF08790.6 CCH61598.1 - 1.5e-13 50.1 8.9 3e-13 49.2 6.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger SRP-alpha_N PF04086.8 CCH61598.1 - 0.021 14.1 4.1 0.028 13.8 2.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-TRAF PF02176.13 CCH61598.1 - 0.063 13.6 2.5 0.12 12.8 1.7 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 CCH61598.1 - 0.12 12.6 5.0 1.3 9.2 1.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCH61598.1 - 0.17 12.3 6.8 0.15 12.4 1.3 2.5 1 1 1 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH61598.1 - 0.28 11.6 4.9 66 4.1 3.4 2.4 1 1 0 1 1 1 0 C2H2-type zinc finger zf-GRF PF06839.7 CCH61598.1 - 0.32 10.9 5.2 0.87 9.5 3.6 1.8 1 0 0 1 1 1 0 GRF zinc finger RNHCP PF12647.2 CCH61598.1 - 0.41 10.4 3.7 0.94 9.3 2.6 1.7 1 1 0 1 1 1 0 RNHCP domain zf-met PF12874.2 CCH61598.1 - 0.44 10.8 5.1 1.4 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type C1_4 PF07975.7 CCH61598.1 - 0.8 9.7 5.9 1.2 9.1 3.5 1.8 1 1 0 1 1 1 0 TFIIH C1-like domain A2L_zn_ribbon PF08792.5 CCH61598.1 - 0.85 9.1 7.8 0.44 10.0 0.5 2.8 1 1 1 2 2 2 0 A2L zinc ribbon domain zf-C2H2_6 PF13912.1 CCH61598.1 - 1.5 8.8 5.9 4.4 7.3 1.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger XPA_N PF01286.13 CCH61598.1 - 2.8 7.7 8.4 8 6.2 1.6 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Prenyltransf PF01255.14 CCH61599.1 - 7.3e-79 264.0 0.4 8.9e-79 263.7 0.3 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase z-alpha PF02295.12 CCH61599.1 - 0.12 12.1 0.3 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Adenosine deaminase z-alpha domain polyprenyl_synt PF00348.12 CCH61600.1 - 2.3e-51 174.1 0.0 1.1e-23 83.4 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase Aldedh PF00171.17 CCH61602.1 - 2.6e-157 523.8 0.0 3e-157 523.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCH61602.1 - 0.018 14.2 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Ctr PF04145.10 CCH61603.1 - 3 7.9 5.7 48 3.9 4.0 2.6 1 1 0 1 1 1 0 Ctr copper transporter family RCR PF12273.3 CCH61604.1 - 4.9e-05 23.9 0.1 0.00011 22.7 0.0 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Maf1 PF09174.5 CCH61606.1 - 6.2e-44 149.9 19.4 1.1e-39 136.0 13.5 2.9 1 1 0 1 1 1 1 Maf1 regulator Macoilin PF09726.4 CCH61606.1 - 0.1 10.8 9.7 0.1 10.8 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Sel1 PF08238.7 CCH61607.1 - 1.8e-05 25.1 1.4 0.68 10.6 0.0 3.4 3 0 0 3 3 3 3 Sel1 repeat Tcp11 PF05794.8 CCH61608.1 - 1e-119 400.1 8.1 1.5e-119 399.6 5.6 1.2 1 0 0 1 1 1 1 T-complex protein 11 Peptidase_A2B PF12384.3 CCH61609.1 - 1.1e-12 47.6 0.0 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ty3 transposon peptidase RVP_2 PF08284.6 CCH61609.1 - 4.5e-07 29.8 0.0 7.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVT_1 PF00078.22 CCH61609.1 - 4.5e-06 26.1 0.0 6.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CCH61609.1 - 1.1e-05 25.8 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCH61609.1 - 0.00086 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease rve PF00665.21 CCH61611.1 - 1.1e-14 54.6 0.0 2.5e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain PIR PF00399.14 CCH61612.1 - 5.5e-48 158.7 77.7 9.6e-09 34.2 2.3 6.8 6 0 0 6 6 6 6 Yeast PIR protein repeat Cornifin PF02389.10 CCH61612.1 - 0.00089 19.0 6.7 0.0013 18.5 4.7 1.3 1 0 0 1 1 1 1 Cornifin (SPRR) family Hamartin PF04388.7 CCH61612.1 - 1.1 7.8 11.7 1.7 7.2 8.1 1.2 1 0 0 1 1 1 0 Hamartin protein DUF4644 PF15486.1 CCH61612.1 - 2.1 8.2 5.1 1.1 9.1 1.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4644) Aldo_ket_red PF00248.16 CCH61613.1 - 4.1e-38 130.8 0.0 4.6e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 CCH61614.1 - 3.1e-41 140.6 0.0 5.4e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH61614.1 - 7.7e-07 29.3 0.2 0.00028 21.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCH61614.1 - 8.6e-06 25.7 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CCH61614.1 - 9.8e-06 24.6 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 CCH61614.1 - 1.3e-05 24.9 0.2 5.4e-05 22.9 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH61614.1 - 0.00029 20.8 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CCH61614.1 - 0.00073 18.6 0.0 0.0013 17.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CCH61614.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCH61614.1 - 0.0026 17.6 0.0 0.0065 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH61614.1 - 0.0042 17.8 0.7 0.011 16.5 0.1 2.1 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CCH61614.1 - 0.0068 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCH61614.1 - 0.0069 16.1 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CCH61614.1 - 0.0076 15.6 1.3 0.19 11.0 0.2 2.4 1 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CCH61614.1 - 0.0086 14.9 0.0 0.037 12.8 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 CCH61614.1 - 0.0087 16.3 0.3 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCH61614.1 - 0.0098 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 CCH61614.1 - 0.011 15.3 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCH61614.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CCH61614.1 - 0.015 14.0 0.0 0.034 12.8 0.0 1.6 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 CCH61614.1 - 0.03 13.9 0.2 0.32 10.6 0.0 2.4 1 1 0 2 2 2 0 NACHT domain PhoH PF02562.11 CCH61614.1 - 0.034 13.3 0.2 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 CCH61614.1 - 0.037 14.1 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CCH61614.1 - 0.046 12.8 0.2 0.38 9.8 0.1 2.1 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 CCH61614.1 - 0.049 12.7 0.1 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCH61614.1 - 0.055 13.0 0.2 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 CCH61614.1 - 0.063 13.1 0.0 0.43 10.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 CCH61614.1 - 0.064 12.9 0.1 0.58 9.8 0.0 2.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 CCH61614.1 - 0.1 12.9 0.5 0.78 10.0 0.3 2.3 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 CCH61614.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C PF00481.16 CCH61615.1 - 6e-76 255.2 0.6 1.3e-75 254.1 0.4 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C EMP24_GP25L PF01105.19 CCH61616.1 - 2.6e-26 92.4 0.5 2.9e-26 92.2 0.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Njmu-R1 PF15053.1 CCH61616.1 - 0.0026 16.5 0.2 0.0032 16.2 0.1 1.1 1 0 0 1 1 1 1 Mjmu-R1-like protein family Syntaxin-6_N PF09177.6 CCH61616.1 - 0.11 12.9 3.6 0.18 12.2 2.5 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CCDC-167 PF15188.1 CCH61616.1 - 0.3 11.0 3.0 0.45 10.5 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-RING_5 PF14634.1 CCH61617.1 - 0.0015 18.2 0.1 0.0015 18.2 0.1 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCH61617.1 - 0.0016 18.0 0.2 0.0046 16.5 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH61617.1 - 0.0019 18.2 0.1 0.0052 16.7 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH61617.1 - 0.029 14.2 0.4 0.029 14.2 0.3 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CCH61617.1 - 0.041 13.7 0.1 0.041 13.7 0.1 1.9 2 0 0 2 2 2 0 Ring finger domain Fer2_3 PF13085.1 CCH61617.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Dynamin_N PF00350.18 CCH61617.1 - 0.12 12.1 3.2 5.8 6.7 0.3 2.7 3 0 0 3 3 3 0 Dynamin family IBR PF01485.16 CCH61617.1 - 0.38 10.6 4.3 11 6.0 1.3 2.6 1 1 1 2 2 2 0 IBR domain Peptidase_U57 PF05582.7 CCH61617.1 - 3.1 6.6 5.4 0.41 9.5 0.3 1.9 2 0 0 2 2 2 0 YabG peptidase U57 vMSA PF00695.14 CCH61618.1 - 0.026 13.7 1.3 0.028 13.6 0.9 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SIT PF15330.1 CCH61618.1 - 0.24 11.5 2.7 0.5 10.5 1.9 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT CYSTM PF12734.2 CCH61618.1 - 0.45 10.6 23.8 17 5.5 12.0 3.4 2 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance Mannosyl_trans3 PF11051.3 CCH61619.1 - 9.5e-90 300.6 0.0 1.6e-89 299.8 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative DUF2977 PF11192.3 CCH61619.1 - 0.0049 16.6 0.3 0.11 12.3 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2977) Glutaredoxin PF00462.19 CCH61620.1 - 3.9e-12 45.9 0.0 8.3e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Pyrophosphatase PF00719.14 CCH61621.1 - 4.1e-53 178.9 0.2 6.4e-53 178.3 0.2 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Histone PF00125.19 CCH61622.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCH61622.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCH61622.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCH61622.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCH61623.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH61623.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCH61623.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCH61623.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCH61623.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCH61623.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCH61623.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCH61623.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit NAD_Gly3P_dh_N PF01210.18 CCH61624.1 - 4.5e-50 169.4 0.0 8.7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CCH61624.1 - 2.9e-46 156.8 0.1 4.3e-46 156.3 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CCH61624.1 - 0.00052 20.3 0.0 3.1 8.3 0.0 3.3 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CCH61624.1 - 0.033 14.4 0.0 0.092 13.0 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF21 PF01595.15 CCH61625.1 - 2.6e-29 101.8 0.2 4.1e-29 101.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCH61625.1 - 0.019 14.7 0.0 0.25 11.1 0.0 2.6 2 1 0 2 2 2 0 CBS domain Pkinase PF00069.20 CCH61626.1 - 5.8e-57 192.7 0.0 1.1e-56 191.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61626.1 - 8.2e-20 70.9 0.0 1.4e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61626.1 - 0.00023 20.2 0.0 0.0006 18.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH61626.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pribosyl_synth PF14572.1 CCH61627.1 - 1.1e-43 149.1 0.3 1.9e-43 148.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCH61627.1 - 2.2e-38 130.5 1.1 2.3e-37 127.2 0.0 2.8 4 0 0 4 4 4 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCH61627.1 - 1.4e-14 53.9 0.1 3.4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCH61627.1 - 0.0089 15.2 0.2 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HTH_17 PF12728.2 CCH61627.1 - 0.043 14.0 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Adap_comp_sub PF00928.16 CCH61628.1 - 1.3e-74 250.6 0.1 1.6e-74 250.3 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family CRT10 PF08728.5 CCH61629.1 - 1.1e-132 443.4 0.4 1.7e-132 442.8 0.3 1.3 1 1 0 1 1 1 1 CRT10 Pkinase PF00069.20 CCH61630.1 - 5.2e-52 176.5 0.0 1.7e-51 174.9 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61630.1 - 2.2e-24 85.9 0.0 4.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Actin PF00022.14 CCH61631.1 - 6.1e-115 383.7 0.0 7.3e-115 383.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCH61631.1 - 0.034 12.7 0.0 0.28 9.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein tRNA_Me_trans PF03054.11 CCH61632.1 - 1.4e-110 369.2 0.0 1.7e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 CCH61632.1 - 9.6e-07 27.9 0.0 8.4e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 CCH61632.1 - 0.0005 19.6 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase Exo_endo_phos PF03372.18 CCH61633.1 - 3.1e-16 60.0 0.0 3.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NARP1 PF12569.3 CCH61634.1 - 1.8e-115 386.6 18.8 5.2e-82 276.2 0.7 3.1 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 CCH61634.1 - 1.2e-16 59.1 4.4 0.0009 18.9 0.0 8.1 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCH61634.1 - 1.8e-14 53.9 0.1 0.0013 19.3 0.0 6.3 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCH61634.1 - 2.2e-13 49.6 6.9 0.041 13.5 0.3 5.7 6 0 0 6 6 6 4 TPR repeat TPR_19 PF14559.1 CCH61634.1 - 1.1e-12 48.0 0.2 0.005 17.1 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCH61634.1 - 9e-10 38.3 0.0 0.048 14.3 0.0 7.2 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCH61634.1 - 4.3e-08 32.9 2.3 0.031 14.2 0.1 5.6 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCH61634.1 - 4.7e-08 32.3 7.9 0.016 14.8 0.0 6.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH61634.1 - 1.2e-07 31.3 3.0 0.12 12.5 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCH61634.1 - 1.7e-07 30.5 12.8 0.047 13.4 0.0 7.5 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH61634.1 - 0.0016 18.0 1.2 9.2 6.3 0.0 5.9 8 0 0 8 8 8 1 Tetratricopeptide repeat WD-3 PF09765.4 CCH61634.1 - 0.0019 17.5 0.1 0.0069 15.7 0.0 2.0 1 0 0 1 1 1 1 WD-repeat region TPR_6 PF13174.1 CCH61634.1 - 0.0046 17.3 4.4 0.35 11.4 0.0 5.8 8 0 0 8 8 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 CCH61634.1 - 0.0097 15.6 0.1 6.1 6.7 0.0 3.2 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region Fis1_TPR_C PF14853.1 CCH61634.1 - 0.018 14.9 10.2 0.72 9.7 0.1 4.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat HLH PF00010.21 CCH61635.1 - 3.4e-18 65.0 0.1 6.2e-18 64.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Phage_connect_1 PF05135.8 CCH61635.1 - 0.053 13.6 0.6 0.053 13.6 0.4 1.8 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Macoilin PF09726.4 CCH61635.1 - 0.25 9.6 2.1 0.35 9.1 1.4 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF904 PF06005.7 CCH61635.1 - 2.3 8.5 5.4 1.4 9.2 0.5 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF904) SIR2 PF02146.12 CCH61636.1 - 1.5e-62 210.4 0.0 6.3e-62 208.4 0.0 1.8 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.8 CCH61636.1 - 8.5e-41 139.0 0.0 1.5e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 CCH61636.1 - 0.016 14.9 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-met PF12874.2 CCH61637.1 - 1.1e-05 25.3 1.5 2.3e-05 24.4 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCH61637.1 - 0.035 14.2 0.2 0.07 13.2 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CHCH PF06747.8 CCH61639.1 - 0.00046 20.0 1.3 0.00062 19.6 0.9 1.2 1 0 0 1 1 1 1 CHCH domain E1_DerP2_DerF2 PF02221.10 CCH61640.1 - 7e-22 78.1 0.0 7.5e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 ML domain NPCBM_assoc PF10633.4 CCH61640.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Metallophos PF00149.23 CCH61641.1 - 9.3e-44 149.2 0.2 1.2e-43 148.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH61641.1 - 0.0021 17.8 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PCI PF01399.22 CCH61642.1 - 1.8e-12 47.4 0.3 1.8e-12 47.4 0.2 2.7 3 1 1 4 4 4 1 PCI domain DUF3969 PF13108.1 CCH61642.1 - 0.029 14.0 0.6 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) RasGAP_C PF03836.10 CCH61642.1 - 0.16 11.6 4.6 3.5 7.3 0.1 2.6 3 0 0 3 3 3 0 RasGAP C-terminus Smg4_UPF3 PF03467.10 CCH61643.1 - 8.4e-19 68.2 1.4 8.4e-19 68.2 0.9 3.2 3 0 0 3 3 3 1 Smg-4/UPF3 family PRP38 PF03371.10 CCH61644.1 - 1e-43 148.9 1.4 1.3e-43 148.6 1.0 1.0 1 0 0 1 1 1 1 PRP38 family DER1 PF04511.10 CCH61646.1 - 0.0025 17.3 10.6 0.0041 16.6 7.3 1.4 1 0 0 1 1 1 1 Der1-like family DUF3099 PF11298.3 CCH61646.1 - 9.8 6.0 7.7 6.4 6.5 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) ABC_tran PF00005.22 CCH61647.1 - 1.2e-52 177.7 0.0 1.1e-25 90.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 CCH61647.1 - 1.1e-37 129.2 40.4 8.7e-27 93.6 9.2 2.7 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 CCH61647.1 - 7.1e-13 49.1 21.9 2e-07 31.2 2.9 5.5 5 1 0 5 5 4 3 AAA domain DUF258 PF03193.11 CCH61647.1 - 5.5e-10 38.6 0.4 9.8e-05 21.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCH61647.1 - 1.2e-08 35.1 0.0 0.0031 17.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CCH61647.1 - 3.9e-08 34.1 0.1 0.0049 17.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCH61647.1 - 2.6e-07 30.9 0.1 0.009 16.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCH61647.1 - 5.4e-07 29.0 2.4 0.027 13.9 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CCH61647.1 - 5e-06 25.9 3.7 0.0034 16.6 0.1 4.0 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CCH61647.1 - 1.7e-05 24.3 0.0 0.0057 16.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CCH61647.1 - 2.3e-05 24.5 0.4 0.39 10.8 0.0 3.8 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CCH61647.1 - 2.7e-05 24.1 0.3 0.064 13.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 CCH61647.1 - 2.7e-05 23.7 2.3 0.047 13.1 0.0 2.6 2 1 0 2 2 2 2 AAA-like domain AAA_28 PF13521.1 CCH61647.1 - 3.9e-05 23.6 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CCH61647.1 - 9.9e-05 21.5 20.5 0.39 9.6 0.0 5.6 5 1 0 6 6 5 3 AAA ATPase domain NACHT PF05729.7 CCH61647.1 - 0.00014 21.6 0.1 0.028 14.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 CCH61647.1 - 0.00014 21.6 0.0 0.16 11.6 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CCH61647.1 - 0.00027 20.4 0.4 0.024 14.1 0.1 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 CCH61647.1 - 0.00028 19.8 0.2 0.076 11.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 CCH61647.1 - 0.00071 19.2 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 CCH61647.1 - 0.00074 18.5 0.5 3 6.7 0.0 3.2 3 0 0 3 3 3 1 KAP family P-loop domain SbcCD_C PF13558.1 CCH61647.1 - 0.00089 19.1 0.3 3 7.8 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.10 CCH61647.1 - 0.0011 17.6 0.1 0.0039 15.9 0.0 1.8 2 0 0 2 2 2 1 Adenovirus IVa2 protein Miro PF08477.8 CCH61647.1 - 0.0022 18.5 0.2 3.2 8.2 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 CCH61647.1 - 0.0029 17.7 0.4 1.5 9.0 0.1 2.7 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 CCH61647.1 - 0.0041 16.8 0.1 0.08 12.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 CCH61647.1 - 0.0046 16.8 0.0 2 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCH61647.1 - 0.0049 16.4 0.0 2.8 7.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CCH61647.1 - 0.013 14.9 3.2 0.48 9.8 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 CCH61647.1 - 0.013 14.7 1.1 0.088 12.0 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_23 PF13476.1 CCH61647.1 - 0.016 15.5 0.3 0.15 12.3 0.1 3.7 3 1 1 4 4 2 0 AAA domain AAA_24 PF13479.1 CCH61647.1 - 0.016 14.7 1.2 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCH61647.1 - 0.027 14.3 0.3 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCH61647.1 - 0.035 13.8 0.3 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CCH61647.1 - 0.057 13.6 0.0 19 5.4 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CCH61647.1 - 0.061 12.8 0.4 4.3 6.8 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 CCH61647.1 - 0.063 13.0 4.9 0.99 9.1 0.2 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF1049 PF06305.6 CCH61647.1 - 0.1 12.0 1.0 0.39 10.2 0.0 2.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1049) ABC_ATPase PF09818.4 CCH61647.1 - 0.2 10.1 0.0 0.52 8.8 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Zeta_toxin PF06414.7 CCH61647.1 - 0.78 8.7 1.3 26 3.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRPRB PF09439.5 CCH61647.1 - 4.1 6.5 7.4 17 4.5 0.0 3.5 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit DUF336 PF03928.9 CCH61648.1 - 6e-22 77.8 0.0 7.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) NatB_MDM20 PF09797.4 CCH61649.1 - 1.2e-63 215.0 14.9 1.2e-63 215.0 10.3 3.3 4 0 0 4 4 4 2 N-acetyltransferase B complex (NatB) non catalytic subunit Brix PF04427.13 CCH61650.1 - 7.6e-41 139.8 0.6 9.8e-41 139.5 0.4 1.1 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 CCH61650.1 - 0.033 14.7 0.0 0.12 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF468) SIN1 PF05422.7 CCH61651.1 - 1.7e-24 86.2 12.6 2.1e-14 52.9 1.5 4.7 4 1 1 5 5 5 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 CCH61651.1 - 0.0032 17.3 0.1 0.009 15.9 0.0 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 CCH61651.1 - 0.063 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain RNase_T PF00929.19 CCH61652.1 - 3.5e-27 95.6 0.0 6e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CCH61652.1 - 0.00025 20.5 0.0 0.00067 19.1 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Str_synth PF03088.11 CCH61652.1 - 0.046 13.7 0.2 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Strictosidine synthase DUF3573 PF12097.3 CCH61652.1 - 0.068 11.7 1.6 0.11 11.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RasGAP PF00616.14 CCH61653.1 - 1.2e-38 132.7 0.8 1.2e-38 132.7 0.6 3.2 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase eRF1_2 PF03464.10 CCH61654.1 - 7.1e-46 155.8 0.2 1.3e-45 154.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCH61654.1 - 2.6e-39 134.0 0.3 5.2e-39 133.0 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCH61654.1 - 2e-27 95.3 0.1 3.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Tnp_DNA_bind PF14706.1 CCH61654.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding ZZ PF00569.12 CCH61655.1 - 2e-07 30.4 5.1 4.2e-07 29.3 3.6 1.6 1 1 0 1 1 1 1 Zinc finger, ZZ type ATG19_autophagy PF12744.2 CCH61655.1 - 3.4e-06 26.5 4.3 3.4e-06 26.5 3.0 2.8 2 1 1 3 3 3 1 Autophagy protein Atg19, Atg8-binding DUF3795 PF12675.2 CCH61655.1 - 0.97 9.6 5.2 0.11 12.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) Ribosomal_S9 PF00380.14 CCH61656.1 - 1.1e-38 132.1 0.4 3.1e-38 130.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 CENP-S PF15630.1 CCH61657.1 - 1e-23 83.3 0.0 1.2e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCH61657.1 - 0.0003 20.1 0.1 0.00038 19.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-18kDa PF02269.11 CCH61657.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3337 PF11816.3 CCH61658.1 - 7.4e-12 45.3 23.2 7.4e-12 45.3 16.1 4.3 3 1 0 3 3 3 1 Domain of unknown function (DUF3337) WD40 PF00400.27 CCH61658.1 - 2.5e-11 42.9 7.2 0.00054 19.7 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat RNA_pol_Rpb5_C PF01191.14 CCH61659.1 - 3.5e-34 116.2 0.5 6.3e-34 115.4 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CCH61659.1 - 2.6e-33 114.3 0.2 4.5e-33 113.5 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.9 CCH61659.1 - 0.018 15.0 0.1 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.7 CCH61659.1 - 0.043 13.6 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease RibD_C PF01872.12 CCH61660.1 - 1.4e-31 109.7 0.0 1.6e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Mem_trans PF03547.13 CCH61661.1 - 4.8 5.3 5.5 4.3 5.5 3.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Sbi-IV PF11621.3 CCH61661.1 - 5.6 7.2 9.4 4.9 7.3 0.4 2.9 2 1 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Suc_Fer-like PF06999.7 CCH61662.1 - 7.3e-52 176.6 0.0 7.3e-52 176.6 0.0 1.4 2 0 0 2 2 2 1 Sucrase/ferredoxin-like DUF899 PF05988.7 CCH61662.1 - 0.064 12.6 0.2 0.092 12.1 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Fungal_trans PF04082.13 CCH61663.1 - 7.7e-23 80.6 11.8 7.7e-23 80.6 8.2 2.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH61663.1 - 6.2e-07 29.2 12.4 1.3e-06 28.2 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.23 CCH61664.1 - 1.2e-15 57.2 0.1 3.3e-15 55.9 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain EnY2 PF10163.4 CCH61665.1 - 2.6e-22 78.5 5.7 3e-22 78.3 4.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF3213 PF11491.3 CCH61665.1 - 1.8 8.4 8.7 7.1 6.5 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3213) TPR_1 PF00515.23 CCH61666.1 - 9.7e-44 145.2 21.4 2.2e-07 30.1 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61666.1 - 2.3e-39 130.1 23.8 0.00012 21.7 0.0 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 CCH61666.1 - 1.6e-38 130.1 24.3 4e-11 42.4 0.3 6.4 1 1 6 8 8 8 8 TPR repeat TPR_17 PF13431.1 CCH61666.1 - 2.9e-27 92.5 22.1 0.00027 20.8 0.0 11.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCH61666.1 - 2.4e-25 88.2 32.2 2.9e-08 33.5 0.1 7.6 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_16 PF13432.1 CCH61666.1 - 8.9e-22 77.2 20.8 4.4e-06 27.2 0.5 6.8 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCH61666.1 - 8.3e-20 69.5 22.0 0.0036 17.8 0.1 9.9 3 2 7 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCH61666.1 - 1.4e-19 68.3 16.1 0.061 13.1 0.1 9.9 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCH61666.1 - 2.3e-14 53.4 18.8 3.1e-05 24.2 0.2 7.1 3 3 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 CCH61666.1 - 5.2e-14 50.8 22.7 0.076 12.8 0.0 9.5 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 CCH61666.1 - 7.1e-12 44.9 16.1 1.1 9.8 0.0 9.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCH61666.1 - 2.2e-11 43.4 11.4 0.017 14.9 0.0 5.8 3 1 2 5 5 5 4 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.11 CCH61667.1 - 2.8e-73 246.2 0.0 3.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CCH61667.1 - 2.1e-30 104.8 0.3 5e-30 103.5 0.2 1.7 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.22 CCH61668.1 - 5.6e-09 35.1 13.7 6.4e-09 35.0 7.5 2.5 2 0 0 2 2 2 1 GATA zinc finger Serglycin PF04360.7 CCH61669.1 - 0.00011 21.9 0.1 0.00015 21.5 0.1 1.2 1 0 0 1 1 1 1 Serglycin AF-4 PF05110.8 CCH61669.1 - 1.3 6.8 5.8 1.7 6.4 4.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3246 PF11596.3 CCH61669.1 - 3.2 6.9 6.1 5 6.3 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) rRNA_proc-arch PF13234.1 CCH61671.1 - 2.4e-90 302.3 1.6 5.2e-90 301.2 1.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CCH61671.1 - 1.8e-60 203.2 0.5 3.8e-60 202.2 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCH61671.1 - 3e-22 78.9 0.0 5.1e-21 74.8 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61671.1 - 2.5e-06 27.2 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCH61671.1 - 0.23 11.2 0.0 0.63 9.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain zf-H2C2_2 PF13465.1 CCH61673.1 - 5.7e-24 83.1 40.1 2.4e-09 37.0 0.6 7.0 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCH61673.1 - 1.4e-21 75.4 56.7 1.3e-05 25.2 0.4 9.0 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH61673.1 - 5.5e-07 29.4 60.5 0.0079 16.4 2.1 8.6 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCH61673.1 - 1.8e-05 24.7 30.6 0.033 14.3 1.1 6.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCH61673.1 - 0.001 18.8 28.5 0.0032 17.3 0.5 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 CCH61673.1 - 0.0032 17.6 32.1 0.026 14.7 1.9 5.8 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CCH61673.1 - 0.89 9.3 14.5 0.28 10.9 0.1 4.3 4 0 0 4 4 4 0 zinc-finger of a C2HC-type XPA_N PF01286.13 CCH61673.1 - 2.1 8.0 12.9 6.3 6.5 0.1 3.9 3 0 0 3 3 3 0 XPA protein N-terminal Nup88 PF10168.4 CCH61674.1 - 1.9e-07 29.3 15.5 1.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore component IncA PF04156.9 CCH61674.1 - 7.7 6.0 11.9 0.44 10.1 3.7 2.1 2 0 0 2 2 2 0 IncA protein Ribosomal_L37 PF08561.5 CCH61675.1 - 5.8e-26 89.8 1.5 8.7e-26 89.3 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.17 CCH61676.1 - 7.3e-15 55.1 1.6 5.1e-10 39.2 0.0 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCH61676.1 - 2.6e-06 27.0 0.1 6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-C2H2_2 PF12756.2 CCH61677.1 - 9.4e-34 115.5 6.6 9.9e-32 109.0 2.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CCH61677.1 - 2.5 7.8 7.3 9.1 6.0 1.0 3.1 2 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Ribosomal_L17 PF01196.14 CCH61679.1 - 6.7e-16 58.6 1.9 1.4e-15 57.6 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein L17 DSPc PF00782.15 CCH61680.1 - 3.1e-31 107.7 1.7 2e-22 79.1 0.1 3.3 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCH61680.1 - 7.8e-05 22.1 0.0 0.015 14.6 0.0 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase CDKN3 PF05706.7 CCH61680.1 - 0.023 14.1 0.1 0.023 14.1 0.1 2.7 3 1 0 3 3 3 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CCH61680.1 - 0.033 14.2 0.1 0.085 12.9 0.1 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate CBFD_NFYB_HMF PF00808.18 CCH61681.1 - 7.9e-06 25.8 0.4 1.4e-05 25.0 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndufs5 PF10200.4 CCH61681.1 - 0.0057 16.6 0.0 0.0091 15.9 0.0 1.4 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF1798 PF08807.5 CCH61681.1 - 0.019 14.6 0.5 0.92 9.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial domain of unknown function (DUF1798) DUF1399 PF07173.7 CCH61681.1 - 0.084 13.1 0.5 0.12 12.7 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1399) FF PF01846.14 CCH61681.1 - 0.16 11.9 0.3 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 FF domain Aa_trans PF01490.13 CCH61682.1 - 6.1e-92 308.2 27.2 7e-92 308.0 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2970 PF11174.3 CCH61682.1 - 0.38 10.3 0.0 0.38 10.3 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) Aa_trans PF01490.13 CCH61683.1 - 1.7e-93 313.3 22.6 1.9e-93 313.1 15.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_S21 PF01165.15 CCH61684.1 - 7.9e-10 38.0 0.1 1.3e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 vMSA PF00695.14 CCH61684.1 - 0.19 10.8 1.5 0.26 10.4 0.9 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus Urm1 PF09138.6 CCH61685.1 - 3.8e-32 110.2 0.1 4.3e-32 110.1 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) DUF544 PF04424.8 CCH61685.1 - 0.016 15.0 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF544) Motile_Sperm PF00635.21 CCH61686.1 - 5.9e-26 90.2 0.1 1.6e-25 88.8 0.1 1.8 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.1 CCH61686.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Med15 PF09606.5 CCH61686.1 - 0.067 11.3 25.7 0.084 11.0 17.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CCH61686.1 - 0.075 12.9 27.7 0.12 12.2 19.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3337 PF11816.3 CCH61686.1 - 0.41 10.0 11.0 0.79 9.0 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF912 PF06024.7 CCH61686.1 - 4.4 7.4 8.4 3.7e+02 1.2 5.7 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAT1 PF09770.4 CCH61686.1 - 5.1 5.1 31.2 6.3 4.9 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_Ag35 PF03286.9 CCH61686.1 - 6.4 6.2 11.0 17 4.8 7.6 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein ArfGap PF01412.13 CCH61687.1 - 2.5e-31 107.9 0.2 2.5e-31 107.9 0.2 3.1 2 1 3 5 5 5 1 Putative GTPase activating protein for Arf 4HBT PF03061.17 CCH61688.1 - 2.6e-07 30.6 0.0 6.1e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily Cnd2 PF05786.9 CCH61689.1 - 1.7e-119 400.4 60.2 1.9e-77 261.4 31.5 2.9 1 1 1 2 2 2 2 Condensin complex subunit 2 Peptidase_M41 PF01434.13 CCH61690.1 - 1.6e-68 230.3 0.1 2.7e-68 229.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCH61690.1 - 4.3e-41 140.1 0.0 1e-40 138.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH61690.1 - 1.5e-05 25.1 1.3 0.014 15.5 0.1 3.6 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CCH61690.1 - 1.8e-05 24.8 0.5 0.00017 21.6 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 CCH61690.1 - 0.00033 19.5 0.0 0.00079 18.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CCH61690.1 - 0.0004 19.5 0.0 0.0025 16.9 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCH61690.1 - 0.00046 21.0 0.1 0.0018 19.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CCH61690.1 - 0.0014 18.3 4.0 0.0018 17.9 0.3 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CCH61690.1 - 0.0015 17.9 1.7 0.17 11.2 0.5 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CCH61690.1 - 0.0018 18.0 0.1 0.0088 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCH61690.1 - 0.004 16.5 0.0 0.0093 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCH61690.1 - 0.0099 15.7 0.0 0.046 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCH61690.1 - 0.016 14.3 0.1 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CCH61690.1 - 0.021 15.1 0.0 0.071 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCH61690.1 - 0.028 13.5 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 CCH61690.1 - 0.047 12.8 0.2 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCH61690.1 - 0.05 13.4 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CCH61690.1 - 0.056 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF4344 PF14247.1 CCH61690.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4344) Sigma54_activat PF00158.21 CCH61690.1 - 0.12 11.8 0.1 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 CCH61690.1 - 0.2 11.6 0.6 0.39 10.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain Herpes_capsid PF06112.6 CCH61690.1 - 4.1 7.4 10.2 0.13 12.3 1.5 2.3 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein Cyclin_N PF00134.18 CCH61691.1 - 1.4e-10 40.8 0.6 4.4e-10 39.2 0.3 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain TB2_DP1_HVA22 PF03134.14 CCH61692.1 - 8.8e-28 95.9 0.9 1.4e-27 95.2 0.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Senescence PF06911.7 CCH61692.1 - 0.046 13.4 9.2 0.066 12.9 6.4 1.2 1 0 0 1 1 1 0 Senescence-associated protein Arrestin_C PF02752.17 CCH61693.1 - 2.7e-20 72.8 0.0 1.8e-18 66.9 0.0 3.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCH61693.1 - 0.012 15.3 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain HLH PF00010.21 CCH61694.1 - 4.8e-13 48.5 0.3 4.8e-13 48.5 0.2 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain zf-HC5HC2H_2 PF13832.1 CCH61695.1 - 5.2e-32 110.1 5.8 5.2e-32 110.1 4.0 2.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCH61695.1 - 1.4e-27 95.6 3.5 1.4e-27 95.6 2.4 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CCH61695.1 - 1.2e-13 50.0 2.5 1.2e-13 50.0 1.7 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 CCH61695.1 - 5.9e-10 38.6 5.0 5.9e-10 38.6 3.5 3.0 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.4 CCH61695.1 - 9.9e-06 25.8 7.0 1.1e-05 25.6 2.0 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-RING-like PF08746.6 CCH61695.1 - 0.0014 18.5 17.8 0.12 12.4 5.8 2.9 2 0 0 2 2 2 2 RING-like domain C1_1 PF00130.17 CCH61695.1 - 0.0074 15.9 0.3 0.0074 15.9 0.2 3.1 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CCH61695.1 - 1.4 8.7 22.2 0.11 12.2 1.7 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 HLH PF00010.21 CCH61696.1 - 4.1e-21 74.4 1.1 9.1e-21 73.3 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CCH61697.1 - 5.5e-60 202.7 0.2 1.1e-59 201.6 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61697.1 - 3.6e-28 98.3 0.0 9.5e-28 96.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCH61697.1 - 6.8e-15 54.9 0.0 2.3e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 CCH61697.1 - 0.0046 15.9 0.0 0.012 14.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCH61697.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3589 PF12141.3 CCH61698.1 - 1.7e-82 277.3 9.2 2.6e-81 273.3 6.4 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) PEPcase_2 PF14010.1 CCH61699.1 - 0.034 12.4 0.4 1.7 6.8 0.1 2.2 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase SOG2 PF10428.4 CCH61700.1 - 1.5e-99 333.6 49.1 1.1e-57 195.6 12.4 4.2 3 1 1 4 4 4 2 RAM signalling pathway protein LRR_4 PF12799.2 CCH61700.1 - 1.1e-18 66.4 17.5 7e-10 38.2 0.7 5.9 5 1 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCH61700.1 - 1.4e-09 37.5 21.3 6.7e-09 35.3 4.2 3.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CCH61700.1 - 3.8e-08 32.2 9.6 0.11 12.7 0.0 6.3 5 0 0 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CCH61700.1 - 9.2e-06 25.0 25.4 0.0071 16.2 0.1 6.6 6 0 0 6 6 6 4 Leucine Rich Repeat SpecificRecomb PF10136.4 CCH61700.1 - 0.0013 16.8 1.6 0.0024 15.9 1.1 1.4 1 0 0 1 1 1 1 Site-specific recombinase PH_10 PF15411.1 CCH61700.1 - 1.3 9.2 7.7 0.19 11.9 1.4 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain Cyto_heme_lyase PF01265.12 CCH61701.1 - 1.8e-65 221.0 0.1 2.2e-65 220.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Sugar_tr PF00083.19 CCH61702.1 - 2.2e-158 527.5 38.3 2.6e-158 527.3 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH61702.1 - 2.1e-35 122.0 31.8 5.5e-35 120.7 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YmzC PF14157.1 CCH61702.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 YmzC-like protein Cytochrom_B_N PF00033.14 CCH61702.1 - 0.0084 15.4 4.8 0.03 13.6 0.2 3.4 3 1 0 3 3 3 1 Cytochrome b(N-terminal)/b6/petB DUF2613 PF11021.3 CCH61702.1 - 0.018 14.7 2.0 0.54 10.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) COPIIcoated_ERV PF07970.7 CCH61703.1 - 2.7e-68 229.9 0.1 3.3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCH61703.1 - 2.1e-29 101.3 1.5 2.7e-29 100.9 0.1 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ETF_QO PF05187.8 CCH61704.1 - 1e-37 128.4 0.0 2.7e-37 127.1 0.0 1.8 2 0 0 2 2 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CCH61704.1 - 6e-09 35.2 0.0 2e-05 23.6 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCH61704.1 - 5.4e-07 29.8 0.0 2.7e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCH61704.1 - 1.4e-06 27.4 0.0 0.006 15.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CCH61704.1 - 3.8e-06 26.8 0.0 1.9e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCH61704.1 - 4.3e-06 25.9 0.0 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.9 CCH61704.1 - 3.2e-05 23.9 0.0 0.00026 20.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCH61704.1 - 0.0003 19.9 0.0 0.00046 19.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.2 CCH61704.1 - 0.00035 20.9 1.0 0.00088 19.6 0.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain HI0933_like PF03486.9 CCH61704.1 - 0.00071 18.1 0.0 0.0013 17.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 CCH61704.1 - 0.0026 18.1 0.0 0.98 9.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCH61704.1 - 0.0047 16.0 0.1 0.008 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 CCH61704.1 - 0.005 16.6 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCH61704.1 - 0.036 12.9 0.1 0.051 12.4 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 CCH61704.1 - 0.044 12.3 0.0 0.17 10.5 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Cyclin_N PF00134.18 CCH61705.1 - 9.7e-20 70.4 1.3 9.7e-20 70.4 0.9 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain ACDC PF14733.1 CCH61706.1 - 0.28 11.3 14.2 1.2 9.3 0.3 4.6 4 1 1 5 5 5 0 AP2-coincident C-terminal TRAM_LAG1_CLN8 PF03798.11 CCH61707.1 - 1.2e-34 119.6 12.4 1.2e-34 119.6 8.6 1.8 2 0 0 2 2 2 1 TLC domain CDP-OH_P_transf PF01066.16 CCH61708.1 - 6.9e-16 58.4 10.1 2.7e-15 56.4 7.0 2.0 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase RNase_PH PF01138.16 CCH61709.1 - 4.8e-21 75.4 0.0 9.1e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCH61709.1 - 4.3e-06 26.5 1.4 8.5e-06 25.6 0.3 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.17 CCH61710.1 - 1.4e-229 763.0 0.1 1.4e-229 763.0 0.1 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCH61710.1 - 2.9e-31 108.2 2.6 2.9e-31 108.2 1.8 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCH61710.1 - 3.1e-17 62.3 0.2 1e-08 34.2 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCH61710.1 - 3.2e-08 33.1 0.1 5.1e-07 29.1 0.0 3.3 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CCH61710.1 - 0.00038 20.4 8.1 0.00038 20.4 5.6 3.0 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 CCH61710.1 - 0.0023 16.8 0.1 0.033 13.0 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CCH61710.1 - 0.0037 16.4 1.9 0.56 9.2 0.0 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Lzipper-MIP1 PF14389.1 CCH61710.1 - 0.02 14.9 5.1 0.049 13.7 3.6 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 tRNA-synt_1c PF00749.16 CCH61710.1 - 1.3 7.5 10.1 1.9 7.0 0.0 4.0 4 0 0 4 4 4 0 tRNA synthetases class I (E and Q), catalytic domain DUF241 PF03087.9 CCH61710.1 - 8.1 5.8 13.1 0.12 11.8 3.3 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function CwfJ_C_1 PF04677.10 CCH61711.1 - 4.5e-27 94.1 0.6 4.5e-27 94.1 0.4 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CCH61711.1 - 1.6e-19 70.1 0.2 3.9e-19 68.9 0.2 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 RNA_pol_A_bac PF01000.21 CCH61712.1 - 2.1e-30 105.1 0.0 4.4e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCH61712.1 - 2.3e-15 55.4 0.0 3.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nrap PF03813.9 CCH61713.1 - 0 1157.4 16.1 0 1157.2 11.2 1.0 1 0 0 1 1 1 1 Nrap protein BSP_II PF05432.6 CCH61713.1 - 0.16 11.2 18.1 0.26 10.5 12.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Tim54 PF11711.3 CCH61713.1 - 1.1 7.7 8.0 1.9 6.9 5.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Daxx PF03344.10 CCH61713.1 - 3.2 6.1 19.9 4.6 5.5 13.8 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 CCH61713.1 - 4.9 6.8 11.5 11 5.6 8.0 1.6 1 0 0 1 1 1 0 FAM176 family DUF3682 PF12446.3 CCH61713.1 - 9.6 6.5 16.7 18 5.6 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Aldo_ket_red PF00248.16 CCH61714.1 - 5.7e-49 166.4 0.0 7e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 CCH61715.1 - 2.1e-21 76.2 2.9 3.2e-21 75.6 2.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61715.1 - 3.9e-10 39.2 1.2 1.1e-09 37.7 0.8 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pil1 PF13805.1 CCH61716.1 - 2.5e-144 479.3 0.2 3.2e-144 479.0 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2457 PF10446.4 CCH61716.1 - 3.7 6.1 14.4 6.5 5.3 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) COG4 PF08318.7 CCH61717.1 - 9.4e-97 323.7 14.1 9.4e-97 323.7 9.8 2.7 2 1 0 2 2 2 1 COG4 transport protein Proteasome PF00227.21 CCH61718.1 - 2.7e-50 170.3 0.1 3.4e-50 169.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit L51_S25_CI-B8 PF05047.11 CCH61719.1 - 7.7e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RPM2 PF08579.6 CCH61719.1 - 0.0079 16.3 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF946 PF06101.6 CCH61719.1 - 0.11 10.4 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) DUF4149 PF13664.1 CCH61720.1 - 4.5e-17 61.9 1.6 7.7e-17 61.2 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF1358 PF07096.6 CCH61720.1 - 0.28 10.8 4.7 0.36 10.5 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) DUF3818 PF12825.2 CCH61721.1 - 2.8e-105 351.7 26.2 2.8e-105 351.7 18.1 3.1 3 0 0 3 3 3 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCH61721.1 - 5.4e-39 132.9 2.4 6e-38 129.5 1.7 2.9 1 1 0 1 1 1 1 PX-associated PX PF00787.19 CCH61721.1 - 1.8e-09 37.4 1.4 1.8e-09 37.4 1.0 2.9 3 0 0 3 3 3 1 PX domain ELFV_dehydrog PF00208.16 CCH61722.1 - 1.4e-79 267.0 2.3 1.8e-79 266.8 1.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CCH61722.1 - 7.3e-46 154.9 0.0 1.2e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MoeA_C PF03454.10 CCH61722.1 - 0.078 12.9 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Calreticulin PF00262.13 CCH61723.1 - 6.5e-109 363.9 15.7 1.1e-108 363.1 10.9 1.4 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.17 CCH61724.1 - 2.9e-177 589.6 0.3 3.3e-177 589.4 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCH61724.1 - 0.053 12.7 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPAM PF02090.10 CCH61725.1 - 0.087 12.8 3.8 0.1 12.6 1.9 1.6 1 1 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Sigma54_AID PF00309.15 CCH61725.1 - 0.19 11.2 1.4 0.42 10.1 1.0 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) MCM PF00493.18 CCH61726.1 - 6.9e-136 452.3 0.1 9.7e-136 451.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCH61726.1 - 6.2e-19 68.6 0.1 2.9e-18 66.5 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCH61726.1 - 3.9e-07 29.4 0.0 1.3e-06 27.7 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCH61726.1 - 0.011 15.1 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 CCH61726.1 - 0.03 13.9 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Phosphorylase PF00343.15 CCH61727.1 - 0 1033.8 1.0 0 1033.5 0.7 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase RNase_H PF00075.19 CCH61730.1 - 0.023 15.0 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 RNase H DUF1454 PF07305.7 CCH61730.1 - 0.12 11.4 0.3 0.23 10.5 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1454) zf-CCHC PF00098.18 CCH61731.1 - 1.8e-10 40.2 29.2 0.00056 19.7 1.0 4.3 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 CCH61731.1 - 0.84 9.3 37.9 0.34 10.6 0.6 5.8 5 1 1 6 6 6 0 Zinc knuckle Dala_Dala_lig_N PF01820.16 CCH61731.1 - 9.7 6.5 7.5 2.2 8.6 0.8 2.8 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus DUF1689 PF07954.6 CCH61732.1 - 1.9e-30 105.7 1.8 2.8e-30 105.1 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Coatomer_E PF04733.9 CCH61733.1 - 2.5e-05 23.6 8.5 0.00018 20.8 5.9 2.1 1 1 0 1 1 1 1 Coatomer epsilon subunit DUF4248 PF14053.1 CCH61733.1 - 0.051 13.1 0.3 0.35 10.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DHO_dh PF01180.16 CCH61734.1 - 1.8e-98 329.1 0.2 2.2e-98 328.8 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCH61734.1 - 0.035 12.9 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PC_rep PF01851.17 CCH61735.1 - 1.6e-41 138.2 19.5 6.5e-06 26.0 0.0 11.1 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CCH61735.1 - 3.1e-17 62.6 5.5 5e-13 49.1 0.0 4.6 3 1 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CCH61735.1 - 2.6e-10 40.4 0.7 0.023 15.1 0.0 4.9 3 1 1 4 4 4 4 HEAT-like repeat HEAT PF02985.17 CCH61735.1 - 9.2e-10 37.7 1.6 0.75 10.0 0.0 5.1 4 0 0 4 4 4 3 HEAT repeat RICTOR_V PF14668.1 CCH61735.1 - 0.002 18.0 0.4 0.18 11.7 0.0 3.6 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Apc3 PF12895.2 CCH61735.1 - 0.026 14.6 1.1 4.5 7.4 0.2 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Vfa1 PF08432.5 CCH61735.1 - 0.038 14.0 13.5 0.058 13.4 7.5 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Arm PF00514.18 CCH61735.1 - 0.074 12.9 0.2 65 3.5 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PI-PLC-Y PF00387.14 CCH61735.1 - 0.089 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain 2-Hacid_dh_C PF02826.14 CCH61736.1 - 2.9e-50 169.8 0.0 5e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCH61736.1 - 2.7e-38 130.4 0.1 3.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCH61736.1 - 0.00021 21.1 0.5 0.0026 17.6 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_1 PF00583.19 CCH61736.1 - 0.0086 16.0 0.0 0.07 13.1 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) family AdoHcyase_NAD PF00670.16 CCH61736.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 CCH61736.1 - 0.041 14.2 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Helicase_C PF00271.26 CCH61736.1 - 0.092 12.6 0.0 1.1 9.1 0.0 2.5 1 1 1 2 2 2 0 Helicase conserved C-terminal domain Not3 PF04065.10 CCH61736.1 - 0.17 11.1 0.2 0.27 10.4 0.2 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component APH PF01636.18 CCH61737.1 - 1.2e-12 48.1 0.0 1.9e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CCH61737.1 - 0.042 12.9 0.0 0.084 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Peptidase_M24 PF00557.19 CCH61738.1 - 5.9e-45 153.4 0.0 8.6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCH61738.1 - 7.6e-25 86.8 0.0 2.7e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain FAD-oxidase_C PF02913.14 CCH61739.1 - 1.9e-56 191.1 0.0 2.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCH61739.1 - 3.2e-35 120.6 0.0 5.1e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 CCH61740.1 - 2.8e-43 147.7 0.0 3.5e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0029 PF01205.14 CCH61741.1 - 2.2e-30 104.5 0.0 2.4e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Pmp3 PF01679.12 CCH61742.1 - 8.9e-19 66.9 5.5 1.3e-18 66.4 3.8 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Na_Ca_ex PF01699.19 CCH61743.1 - 2.2e-51 173.1 31.5 6.7e-26 90.5 9.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.1 CCH61743.1 - 0.11 12.3 1.7 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 YWFCY protein ATP-synt_8 PF00895.15 CCH61743.1 - 0.23 11.7 0.0 0.23 11.7 0.0 3.4 3 0 0 3 3 3 0 ATP synthase protein 8 IATP PF04568.7 CCH61745.1 - 1.9e-17 63.1 0.9 2.1e-17 63.0 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FbpA PF05833.6 CCH61745.1 - 0.002 16.7 3.6 0.002 16.7 2.5 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Rabaptin PF03528.10 CCH61745.1 - 0.0073 16.2 1.1 0.0088 15.9 0.7 1.3 1 0 0 1 1 1 1 Rabaptin P4Ha_N PF08336.6 CCH61745.1 - 0.042 13.6 2.3 0.078 12.7 1.6 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region AAA_23 PF13476.1 CCH61745.1 - 0.069 13.4 2.7 0.067 13.5 1.9 1.1 1 0 0 1 1 1 0 AAA domain Pox_A_type_inc PF04508.7 CCH61745.1 - 0.54 10.1 3.3 1.4 8.9 2.3 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat MARVEL PF01284.18 CCH61746.1 - 1.2e-06 28.4 0.7 1.8e-06 27.7 0.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Atrophin-1 PF03154.10 CCH61747.1 - 0.0092 14.1 1.6 0.012 13.7 1.1 1.1 1 0 0 1 1 1 1 Atrophin-1 family DUF3824 PF12868.2 CCH61747.1 - 0.46 11.4 5.7 1.2 10.0 3.9 1.7 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Metallophos PF00149.23 CCH61748.1 - 1.1e-39 135.9 0.4 1.4e-39 135.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 CCH61749.1 - 5e-60 202.3 3.8 5.6e-60 202.1 2.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor R3H PF01424.17 CCH61750.1 - 2e-08 33.7 0.0 4.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 CCH61750.1 - 0.0052 17.2 0.0 0.0052 17.2 0.0 3.9 4 1 0 4 4 4 1 SUZ domain Ufd2P_core PF10408.4 CCH61751.1 - 1.6e-178 594.8 35.2 1.6e-178 594.8 24.4 1.8 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 CCH61751.1 - 9.5e-28 95.9 0.7 4.4e-27 93.8 0.5 2.3 1 0 0 1 1 1 1 U-box domain QLQ PF08880.6 CCH61751.1 - 0.093 12.1 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 QLQ Ribosomal_L29 PF00831.18 CCH61752.1 - 5.4e-17 61.2 3.9 5.4e-17 61.2 2.7 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Annexin PF00191.15 CCH61752.1 - 0.054 13.3 0.2 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Annexin MRP-L47 PF06984.8 CCH61752.1 - 0.46 10.4 2.4 0.9 9.4 0.4 2.3 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Arf PF00025.16 CCH61753.1 - 1.2e-77 259.0 0.0 1.4e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCH61753.1 - 5.4e-14 51.9 0.0 5.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCH61753.1 - 2e-13 49.9 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCH61753.1 - 4.3e-11 42.3 0.0 5.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCH61753.1 - 5.4e-11 41.8 0.3 7.3e-08 31.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CCH61753.1 - 3.5e-10 40.4 0.0 4.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCH61753.1 - 9.7e-06 25.5 0.0 1.4e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 CCH61753.1 - 0.0035 17.0 0.4 0.45 10.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain GTP_EFTU PF00009.22 CCH61753.1 - 0.0061 16.0 0.0 0.032 13.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CCH61753.1 - 0.0062 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CCH61753.1 - 0.0081 16.0 0.1 0.014 15.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCH61753.1 - 0.041 14.1 0.0 0.069 13.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CCH61753.1 - 0.044 12.8 0.1 0.057 12.4 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 CCH61753.1 - 0.054 12.9 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DBD_Tnp_Mut PF03108.10 CCH61753.1 - 0.1 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase Prenyltransf PF01255.14 CCH61754.1 - 0.00097 18.3 0.0 0.0021 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF2899 PF11449.3 CCH61754.1 - 0.016 14.4 0.0 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) Sugar_tr PF00083.19 CCH61755.1 - 3.1e-121 405.1 27.0 3.7e-121 404.8 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH61755.1 - 8e-17 60.9 31.4 8e-17 60.9 21.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF46 PF01864.12 CCH61755.1 - 0.011 15.5 1.4 0.011 15.5 1.0 2.0 2 1 0 2 2 2 0 Putative integral membrane protein DUF46 Sec31 PF11549.3 CCH61756.1 - 5.3e-17 61.1 3.7 5.3e-17 61.1 2.5 2.3 2 0 0 2 2 2 1 Protein transport protein SEC31 WD40 PF00400.27 CCH61756.1 - 2.1e-16 59.0 7.7 0.00054 19.7 0.0 6.8 8 0 0 8 8 8 4 WD domain, G-beta repeat SRA1 PF07304.6 CCH61756.1 - 1e-06 28.5 0.0 1e-06 28.5 0.0 3.0 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 CCH61756.1 - 2e-05 24.4 2.9 3e-05 23.8 0.4 2.5 2 1 0 2 2 2 1 Prp18 domain BBS2_Mid PF14783.1 CCH61756.1 - 0.095 12.4 0.3 0.47 10.2 0.1 2.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IZUMO PF15005.1 CCH61756.1 - 6.6 6.7 8.3 1.9 8.4 0.0 3.3 3 0 0 3 3 3 0 Izumo sperm-egg fusion CHCH PF06747.8 CCH61757.1 - 2.2e-05 24.2 4.3 4e-05 23.3 3.0 1.4 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.4 CCH61757.1 - 0.064 13.2 0.1 0.084 12.8 0.1 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Scm3 PF10384.4 CCH61758.1 - 3.2e-20 71.3 2.0 8e-20 70.0 1.4 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 RNA_pol_Rpb1_1 PF04997.7 CCH61759.1 - 1.9e-121 405.4 0.1 3.6e-121 404.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CCH61759.1 - 6.9e-106 353.5 0.2 1.1e-105 352.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCH61759.1 - 1.5e-72 242.9 0.1 4.9e-72 241.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CCH61759.1 - 3.1e-61 206.3 0.5 3.1e-61 206.3 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CCH61759.1 - 3.7e-46 156.7 0.1 1.1e-45 155.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CCH61759.1 - 1.1e-44 151.4 4.1 2.2e-44 150.4 2.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CCH61759.1 - 9e-36 121.9 0.1 2.8e-35 120.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CCH61759.1 - 2.2e-14 52.2 274.6 0.037 14.1 7.7 14.6 2 1 24 26 26 26 22 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.1 CCH61759.1 - 0.2 11.6 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BPL_N PF09825.4 CCH61760.1 - 2.9e-123 411.3 0.0 3.5e-123 411.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_C PF02237.12 CCH61760.1 - 2.9e-13 49.2 0.1 6.1e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB PF03099.14 CCH61760.1 - 2.7e-11 43.5 0.0 2e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase PF00117.23 CCH61760.1 - 0.12 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Cpn60_TCP1 PF00118.19 CCH61761.1 - 1.8e-132 442.4 14.0 2.1e-132 442.2 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family D123 PF07065.9 CCH61762.1 - 4.1e-110 367.5 9.3 5.3e-110 367.1 6.4 1.1 1 0 0 1 1 1 1 D123 Hydrolase_3 PF08282.7 CCH61762.1 - 0.12 11.9 2.3 0.1 12.1 0.2 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.16 CCH61763.1 - 7.3e-42 142.7 1.4 9.5e-42 142.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 GlgS PF08971.6 CCH61763.1 - 0.0013 18.6 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen synthesis protein Chitin_bind_1 PF00187.14 CCH61763.1 - 0.14 12.1 12.5 0.26 11.2 8.7 1.4 1 0 0 1 1 1 0 Chitin recognition protein ApbA_C PF08546.6 CCH61764.1 - 3e-21 75.6 0.0 4.5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCH61764.1 - 5.3e-21 74.6 0.0 1.2e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CCH61764.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 CCH61764.1 - 0.025 14.3 0.3 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.22 CCH61764.1 - 0.086 13.2 0.3 0.22 11.9 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCH61764.1 - 0.15 10.9 0.5 0.21 10.4 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Coatomer_WDAD PF04053.9 CCH61765.1 - 2.4e-131 438.5 8.5 3.9e-131 437.9 5.9 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CCH61765.1 - 8.2e-71 238.7 0.1 1.2e-70 238.1 0.1 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CCH61765.1 - 4.9e-59 194.2 15.0 2e-12 46.5 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCH61765.1 - 1.7e-06 26.4 6.6 0.21 9.7 0.2 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CCH61765.1 - 5.6e-06 26.2 2.1 0.12 12.0 0.0 4.4 4 2 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A VD10_N PF08476.5 CCH61766.1 - 0.2 11.1 2.2 0.21 11.0 0.2 2.1 2 0 0 2 2 2 0 Viral D10 N-terminal Spectrin PF00435.16 CCH61766.1 - 0.77 10.0 10.4 2.9 8.2 2.7 2.5 2 1 0 2 2 2 0 Spectrin repeat PIN_4 PF13638.1 CCH61766.1 - 1.8 8.6 5.0 4.4 7.4 0.7 2.2 1 1 1 2 2 2 0 PIN domain DivIC PF04977.10 CCH61766.1 - 2.1 7.9 7.8 0.84 9.1 2.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Ly49 PF08391.5 CCH61766.1 - 2.4 8.3 7.3 0.83 9.8 2.7 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Fib_alpha PF08702.5 CCH61766.1 - 5.8 7.0 11.1 0.4 10.7 2.9 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PCI PF01399.22 CCH61767.1 - 2.8e-22 78.9 3.4 2.9e-22 78.9 0.4 2.4 2 0 0 2 2 2 1 PCI domain Nop14 PF04147.7 CCH61768.1 - 3e-210 700.3 65.4 3.9e-207 690.0 45.3 2.0 1 1 0 1 1 1 1 Nop14-like family APG9 PF04109.11 CCH61769.1 - 1.4e-158 527.6 9.9 2.4e-158 526.8 6.8 1.3 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.9 CCH61770.1 - 8.6e-26 90.4 0.4 8.6e-26 90.4 0.3 2.8 2 1 0 2 2 2 1 RNA polymerase III RPC4 THEG PF14912.1 CCH61770.1 - 0.26 11.8 0.1 0.26 11.8 0.1 2.7 4 1 0 4 4 4 0 Testicular haploid expressed repeat Sas10 PF09368.5 CCH61771.1 - 2.4e-29 101.3 12.8 6.4e-29 99.9 8.2 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CCH61771.1 - 5.3e-12 45.7 0.8 2.1e-11 43.8 0.6 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MutS_V PF00488.16 CCH61772.1 - 3.4e-53 180.4 0.0 2.2e-52 177.7 0.0 2.4 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CCH61772.1 - 1.9e-26 93.1 2.4 1.9e-26 93.1 1.7 2.3 2 0 0 2 2 2 1 MutS domain III AAA_22 PF13401.1 CCH61772.1 - 0.00032 20.8 1.6 0.12 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCH61772.1 - 0.022 14.6 13.5 0.35 10.7 0.0 5.4 3 1 2 5 5 5 0 AAA domain AAA_29 PF13555.1 CCH61772.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyclin_N PF00134.18 CCH61773.1 - 5.7e-43 145.5 0.1 1.4e-42 144.2 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCH61773.1 - 1.4e-31 108.8 0.2 1.4e-31 108.8 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain Nop14 PF04147.7 CCH61773.1 - 2.1 6.1 26.6 3.1 5.6 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CCH61773.1 - 4.7 6.4 24.4 7.8 5.6 16.9 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 CCH61773.1 - 5.4 5.9 20.1 1.9 7.4 12.1 1.6 2 0 0 2 2 2 0 BUD22 WD40 PF00400.27 CCH61774.1 - 1.9e-10 40.1 7.6 0.0023 17.7 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase PF00069.20 CCH61776.1 - 9.1e-67 224.9 0.0 1.4e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH61776.1 - 6.5e-41 140.1 0.0 1e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH61776.1 - 0.00078 18.4 0.0 0.0016 17.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Mito_fiss_reg PF05308.6 CCH61776.1 - 0.077 12.3 8.0 0.15 11.4 5.5 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator RIO1 PF01163.17 CCH61776.1 - 0.68 9.2 0.0 0.68 9.2 0.0 2.8 3 0 0 3 3 3 0 RIO1 family DEAD PF00270.24 CCH61777.1 - 4.9e-41 140.0 0.1 7.8e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61777.1 - 2.1e-25 88.3 0.2 4.6e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pex14_N PF04695.8 CCH61777.1 - 0.018 15.1 2.8 0.035 14.1 1.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CCH61777.1 - 2.6 6.2 15.0 3.8 5.6 10.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PNP_UDP_1 PF01048.15 CCH61778.1 - 2.9e-45 154.0 0.0 3.5e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Zip PF02535.17 CCH61779.1 - 2.1e-60 204.3 0.0 2.7e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 CCH61779.1 - 0.0014 17.9 2.1 0.021 14.0 0.1 2.4 3 0 0 3 3 3 2 UNC-50 family WD40 PF00400.27 CCH61780.1 - 7.4e-43 142.9 22.5 9.7e-11 41.1 0.4 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat YmzC PF14157.1 CCH61780.1 - 0.0091 15.8 0.0 7 6.5 0.0 3.3 4 0 0 4 4 4 2 YmzC-like protein TFIIIC_delta PF12657.2 CCH61780.1 - 0.011 15.4 6.2 0.46 10.1 1.0 3.3 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term NAD_binding_7 PF13241.1 CCH61781.1 - 4.9e-19 68.4 0.0 7.1e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCH61781.1 - 3.9e-06 26.0 0.0 7.3e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCH61781.1 - 0.0011 17.8 0.0 0.0021 16.9 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ELFV_dehydrog PF00208.16 CCH61781.1 - 0.0094 15.5 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.15 CCH61781.1 - 0.05 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 CCH61781.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CBS PF00571.23 CCH61782.1 - 2.5e-25 88.0 0.7 7.2e-06 25.6 0.0 5.0 4 1 0 4 4 4 4 CBS domain COX4 PF02936.9 CCH61783.1 - 0.023 14.4 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV DUF2729 PF10870.3 CCH61783.1 - 0.05 13.3 0.1 7 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) UQ_con PF00179.21 CCH61784.1 - 1.6e-50 170.1 0.1 1.9e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH61784.1 - 2.7e-05 23.9 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCH61784.1 - 0.01 15.6 0.2 0.033 14.0 0.1 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 CCH61784.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 UEV domain DUF2457 PF10446.4 CCH61784.1 - 9.3 4.8 15.3 15 4.1 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BCDHK_Adom3 PF10436.4 CCH61785.1 - 4.4e-31 107.6 1.1 7.4e-31 106.8 0.8 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCH61785.1 - 1.2e-07 31.4 0.0 1.3e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinetochor_Ybp2 PF08568.5 CCH61786.1 - 2.4e-77 260.6 31.8 2.7e-77 260.5 22.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DASH_Duo1 PF08651.5 CCH61787.1 - 1e-17 63.4 1.3 1e-17 63.4 0.9 2.2 2 0 0 2 2 2 1 DASH complex subunit Duo1 DASH_Spc34 PF08657.5 CCH61787.1 - 0.0071 16.0 6.2 0.0071 16.0 4.3 2.3 1 1 1 2 2 2 1 DASH complex subunit Spc34 DUF2400 PF09674.5 CCH61787.1 - 0.19 11.4 3.3 0.27 10.9 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) DUF3153 PF11353.3 CCH61787.1 - 0.68 9.3 4.0 1.2 8.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF2098 PF09871.4 CCH61787.1 - 0.77 9.7 3.9 0.59 10.0 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Bap31 PF05529.7 CCH61787.1 - 1.2 8.5 5.4 0.25 10.7 1.4 1.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like 5_3_exonuc PF01367.15 CCH61787.1 - 1.9 8.7 4.5 9.6 6.5 0.1 2.3 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold CPSase_L_D2 PF02786.12 CCH61788.1 - 8.1e-82 273.5 0.4 1.2e-81 272.9 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCH61788.1 - 1e-63 214.3 0.0 1.7e-63 213.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCH61788.1 - 1.7e-32 111.8 0.0 5.3e-32 110.1 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCH61788.1 - 3.4e-30 104.1 0.0 1.7e-29 101.9 0.0 2.3 3 0 0 3 3 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCH61788.1 - 3e-24 85.9 0.0 6.6e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 CCH61788.1 - 4.7e-18 64.6 2.5 1.6e-17 62.8 1.7 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCH61788.1 - 4.8e-16 59.0 0.2 9.6e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCH61788.1 - 1.3e-14 53.7 0.0 5.4e-14 51.6 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CCH61788.1 - 2.3e-08 33.6 0.0 4.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CCH61788.1 - 4.6e-08 32.5 1.5 0.0014 18.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CCH61788.1 - 7.7e-07 28.6 0.1 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CCH61788.1 - 4.7e-06 26.5 0.0 9.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCH61788.1 - 4.3e-05 23.0 0.1 0.00011 21.6 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 CCH61788.1 - 6.1e-05 22.6 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_2 PF12700.2 CCH61788.1 - 0.0029 16.8 0.0 0.26 10.3 0.0 2.3 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CCH61788.1 - 0.018 15.4 0.2 6.6 7.1 0.0 3.4 2 1 1 3 3 2 0 HlyD family secretion protein Med31 PF05669.7 CCH61789.1 - 3.3e-26 91.0 0.0 4.1e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.4 CCH61790.1 - 1.3e-45 155.2 17.2 2e-40 138.3 5.5 2.7 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 CCH61790.1 - 0.0036 16.9 0.1 0.0036 16.9 0.1 2.0 2 1 1 3 3 3 1 PAP2 superfamily WBP-1 PF11669.3 CCH61790.1 - 0.69 10.0 4.7 0.15 12.1 0.6 1.8 1 1 0 1 1 1 0 WW domain-binding protein 1 Acatn PF13000.2 CCH61791.1 - 1.7e-195 650.6 37.7 8.2e-194 645.1 26.1 2.6 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 MTHFR PF02219.12 CCH61792.1 - 1.8e-102 342.2 0.1 2e-101 338.8 0.0 2.1 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase Methyltransf_11 PF08241.7 CCH61793.1 - 0.018 15.5 0.0 0.062 13.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain AAA_2 PF07724.9 CCH61794.1 - 6.4e-35 120.5 4.2 6.2e-34 117.3 1.1 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCH61794.1 - 6.1e-13 49.1 0.7 1.4e-12 47.9 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCH61794.1 - 1.4e-08 34.4 0.3 5.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCH61794.1 - 1.3e-06 28.2 0.2 1.8e-05 24.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCH61794.1 - 3.5e-05 23.9 1.0 0.00057 20.0 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCH61794.1 - 7.1e-05 22.8 0.6 0.0008 19.4 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCH61794.1 - 0.00087 20.1 0.7 0.0024 18.6 0.1 2.3 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CCH61794.1 - 0.0012 18.0 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCH61794.1 - 0.0019 18.0 0.6 0.007 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCH61794.1 - 0.0042 16.5 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein CbiA PF01656.18 CCH61794.1 - 0.0056 16.1 0.1 0.067 12.5 0.0 2.4 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.21 CCH61794.1 - 0.0083 15.6 0.0 1 8.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 CCH61794.1 - 0.026 14.1 0.2 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 NACHT domain RuvB_N PF05496.7 CCH61794.1 - 0.037 13.0 0.0 0.094 11.7 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CCH61794.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 CCH61794.1 - 0.058 13.4 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_polI_A14 PF08203.6 CCH61794.1 - 0.12 12.6 0.5 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 FtsK_SpoIIIE PF01580.13 CCH61794.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.1 CCH61794.1 - 0.96 9.7 10.0 0.11 12.7 1.0 3.4 3 1 1 4 4 4 0 AAA domain GIY-YIG PF01541.19 CCH61795.1 - 1.2e-08 35.1 0.0 3.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain Ribonuclease_3 PF00636.21 CCH61795.1 - 0.11 12.9 0.1 1.3 9.4 0.1 2.5 1 1 0 1 1 1 0 Ribonuclease III domain zf-rbx1 PF12678.2 CCH61795.1 - 0.5 10.5 4.9 2.4 8.3 3.3 2.3 1 1 1 2 2 2 0 RING-H2 zinc finger Mon1 PF03164.9 CCH61796.1 - 1.4e-103 346.6 19.3 2.8e-103 345.7 13.4 1.5 1 1 0 1 1 1 1 Trafficking protein Mon1 SPT2 PF08243.6 CCH61796.1 - 0.2 11.9 1.9 0.47 10.7 0.1 2.4 2 0 0 2 2 2 0 SPT2 chromatin protein Ribosomal_S5 PF00333.15 CCH61797.1 - 3.8e-28 97.0 6.2 4.6e-28 96.7 2.1 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCH61797.1 - 1.4e-21 75.5 0.0 2.6e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Nab2 PF11517.3 CCH61798.1 - 2.1e-45 153.2 4.1 3.7e-45 152.4 2.9 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 CCH61798.1 - 6.6e-11 41.7 67.9 6.7e-05 22.7 3.1 7.6 7 1 0 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type DUF2508 PF10704.4 CCH61798.1 - 0.35 11.0 0.1 0.35 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) HA2 PF04408.18 CCH61799.1 - 2.7e-25 88.3 0.1 6e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCH61799.1 - 4.6e-25 87.6 0.0 1e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCH61799.1 - 3.1e-11 42.9 0.0 6.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH61799.1 - 1.8e-09 37.3 0.3 3e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH61799.1 - 1.5e-06 28.3 0.1 6.4e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CCH61799.1 - 3.7e-05 23.2 0.1 9.5e-05 21.9 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 CCH61799.1 - 0.00011 22.1 0.2 0.0041 16.9 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CCH61799.1 - 0.00041 20.1 0.2 0.00082 19.1 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 CCH61799.1 - 0.003 16.4 0.0 0.006 15.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 CCH61799.1 - 0.0042 17.4 0.0 0.059 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCH61799.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CCH61799.1 - 0.088 12.0 0.0 0.32 10.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 CCH61799.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_C12 PF01088.16 CCH61800.1 - 2.5e-50 170.6 0.0 3e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.11 CCH61801.1 - 4.6e-48 163.4 3.4 6.8e-48 162.9 2.4 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCH61801.1 - 0.00036 20.3 1.8 0.0008 19.1 0.9 1.7 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Na_trans_assoc PF06512.8 CCH61801.1 - 0.58 10.0 6.3 0.2 11.6 2.0 1.8 2 0 0 2 2 2 0 Sodium ion transport-associated ESCRT-II PF05871.7 CCH61802.1 - 1.6e-44 151.1 1.4 2e-44 150.8 0.9 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Rft-1 PF04506.8 CCH61802.1 - 0.026 12.9 0.1 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 Rft protein DUF2408 PF10303.4 CCH61803.1 - 0.00061 19.9 3.9 0.001 19.2 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) TMCO5 PF14992.1 CCH61803.1 - 0.0071 15.5 3.6 0.01 15.0 2.5 1.2 1 0 0 1 1 1 1 TMCO5 family Mod_r PF07200.8 CCH61803.1 - 0.0095 15.8 3.5 0.02 14.8 2.4 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein MerR-DNA-bind PF09278.6 CCH61803.1 - 0.015 15.7 2.0 0.021 15.1 0.3 2.1 2 0 0 2 2 2 0 MerR, DNA binding Fmp27_WPPW PF10359.4 CCH61803.1 - 0.017 13.5 0.9 0.026 12.9 0.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Myb_CC_LHEQLE PF14379.1 CCH61803.1 - 0.027 14.0 0.8 1.6 8.3 0.0 2.6 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif DUF3166 PF11365.3 CCH61803.1 - 0.041 14.3 0.6 0.71 10.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) DUF904 PF06005.7 CCH61803.1 - 0.28 11.5 7.9 0.067 13.4 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CCH61803.1 - 0.38 10.7 5.1 2.3 8.2 0.1 3.0 2 1 1 3 3 3 0 bZIP transcription factor Prefoldin PF02996.12 CCH61803.1 - 2.8 7.6 10.2 0.88 9.2 0.6 3.2 3 1 1 4 4 4 0 Prefoldin subunit FliT PF05400.8 CCH61803.1 - 3.1 8.2 9.9 0.26 11.7 2.7 2.3 3 1 1 4 4 4 0 Flagellar protein FliT CTP_synth_N PF06418.9 CCH61804.1 - 1.1e-120 401.9 0.4 1.5e-120 401.4 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CCH61804.1 - 6.8e-56 188.7 0.0 1e-55 188.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCH61804.1 - 4.4e-06 26.2 0.0 1.6e-05 24.5 0.0 1.9 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CCH61804.1 - 0.0025 17.2 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2418 PF10332.4 CCH61805.1 - 0.05 13.9 0.2 0.052 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) ER_lumen_recept PF00810.13 CCH61806.1 - 1.1e-50 172.0 13.7 1.5e-50 171.4 9.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor Proteasome PF00227.21 CCH61807.1 - 1.2e-35 122.5 0.1 9.6e-35 119.5 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit KilA-N PF04383.8 CCH61809.1 - 0.053 13.1 1.6 0.092 12.3 1.1 1.4 1 0 0 1 1 1 0 KilA-N domain Peptidase_M16_C PF05193.16 CCH61810.1 - 8.8e-23 80.9 1.7 2.9e-22 79.2 0.1 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCH61810.1 - 4e-18 65.5 0.4 6.7e-18 64.8 0.3 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.6 CCH61811.1 - 8.9e-27 94.3 56.2 8.9e-27 94.3 38.9 4.1 2 1 1 3 3 3 1 PPP4R2 DUF1133 PF06576.6 CCH61811.1 - 0.023 13.8 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) ASFV_J13L PF05568.6 CCH61811.1 - 1.7 8.1 8.0 2.8 7.4 5.5 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_S7 PF00177.16 CCH61812.1 - 4.9e-30 104.0 0.0 8.1e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Apolipoprotein PF01442.13 CCH61812.1 - 0.0017 17.9 0.0 0.058 12.8 0.0 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain VanZ PF04892.7 CCH61813.1 - 9e-09 35.3 6.3 1.1e-07 31.9 4.3 2.2 1 1 0 1 1 1 1 VanZ like family DUF4118 PF13493.1 CCH61813.1 - 0.19 11.9 2.2 0.54 10.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) DUF1056 PF06341.6 CCH61813.1 - 0.4 10.7 3.0 2.1 8.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) DUF1673 PF07895.6 CCH61813.1 - 2.2 7.7 6.5 2.6 7.5 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Pox_A14 PF05767.7 CCH61813.1 - 3.9 7.4 6.3 12 5.8 1.0 2.3 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF2417 PF10329.4 CCH61813.1 - 4.4 6.6 9.4 2 7.7 0.8 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) EF-hand_4 PF12763.2 CCH61814.1 - 3.5e-34 116.6 0.1 4.9e-11 42.2 0.0 4.1 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CCH61814.1 - 9.3e-10 37.1 0.0 0.00018 20.5 0.0 3.8 3 0 0 3 3 3 2 EF hand UBA PF00627.26 CCH61814.1 - 1.6e-09 37.2 0.1 3.4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 CCH61814.1 - 4.5e-09 36.3 0.0 0.011 15.8 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CCH61814.1 - 1.3e-06 27.8 0.0 0.043 13.6 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain UBA_4 PF14555.1 CCH61814.1 - 7.2e-05 22.2 0.3 0.00016 21.1 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain Myosin_tail_1 PF01576.14 CCH61814.1 - 0.00029 18.7 57.6 0.00063 17.6 18.3 2.5 1 1 1 2 2 2 2 Myosin tail CMD PF02627.15 CCH61815.1 - 6.9e-05 22.6 0.0 0.00054 19.7 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family GrpB PF04229.9 CCH61815.1 - 0.094 12.4 0.0 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 GrpB protein PRESAN PF09687.5 CCH61815.1 - 0.25 11.4 7.8 0.27 11.2 3.2 2.4 2 1 0 2 2 2 0 Plasmodium RESA N-terminal Myotub-related PF06602.9 CCH61816.1 - 3e-120 401.2 10.3 3e-120 401.2 7.2 2.0 2 1 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CCH61816.1 - 0.016 15.4 0.0 0.063 13.5 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 CCH61816.1 - 0.021 14.3 0.0 0.021 14.3 0.0 3.0 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.9 CCH61817.1 - 7.5e-18 64.3 4.7 1.2e-17 63.6 3.3 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNAP PF14938.1 CCH61818.1 - 2.2e-106 355.1 13.5 2.5e-106 354.9 9.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Foie-gras_1 PF11817.3 CCH61818.1 - 7.3e-06 25.6 2.8 7.9e-06 25.5 1.3 1.6 1 1 1 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 CCH61818.1 - 0.0013 18.5 7.8 0.031 14.1 0.7 3.5 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCH61818.1 - 0.0068 16.8 3.6 18 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCH61818.1 - 0.01 15.7 10.1 2.7 8.1 0.3 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCH61818.1 - 0.017 14.8 2.7 0.12 12.2 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Spatacsin_C PF14649.1 CCH61818.1 - 0.02 13.7 5.1 0.028 13.3 1.4 2.1 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_11 PF13414.1 CCH61818.1 - 0.12 11.9 12.7 0.44 10.2 2.5 4.2 2 1 1 3 3 3 0 TPR repeat TPR_8 PF13181.1 CCH61818.1 - 0.31 10.9 9.9 0.57 10.0 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CCH61818.1 - 4.7 7.1 10.1 6.2 6.7 0.3 4.4 5 1 0 5 5 5 0 MIT (microtubule interacting and transport) domain CPSase_L_D2 PF02786.12 CCH61819.1 - 5.7e-107 355.7 0.0 9.4e-82 273.3 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CCH61819.1 - 1.7e-36 124.6 3.1 9.3e-36 122.3 0.8 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CCH61819.1 - 4.9e-35 119.9 0.0 7e-17 61.5 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CCH61819.1 - 3.3e-28 98.6 0.0 5.9e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCH61819.1 - 1.2e-21 76.7 0.0 2.3e-09 36.4 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCH61819.1 - 2.4e-16 59.5 0.0 5.7e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCH61819.1 - 2.5e-10 40.0 0.1 0.00068 19.0 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 CCH61819.1 - 0.015 15.2 0.2 0.18 11.7 0.0 2.7 2 0 0 2 2 2 0 MGS-like domain AsmA PF05170.9 CCH61820.1 - 0.028 13.0 1.4 0.032 12.8 1.0 1.0 1 0 0 1 1 1 0 AsmA family Pap_E4 PF02711.9 CCH61820.1 - 0.6 10.9 5.3 0.35 11.7 1.7 1.8 1 1 1 2 2 2 0 E4 protein Na_Ca_ex PF01699.19 CCH61821.1 - 2.9e-44 150.0 25.6 4e-29 101.0 4.3 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3147 PF11345.3 CCH61821.1 - 0.29 11.1 9.2 0.67 9.9 1.4 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3147) TRAM_LAG1_CLN8 PF03798.11 CCH61822.1 - 9.8e-31 106.8 23.8 9.8e-31 106.8 16.5 1.9 2 0 0 2 2 2 1 TLC domain TRAM_LAG1_CLN8 PF03798.11 CCH61823.1 - 2.4e-22 79.4 18.4 2.4e-22 79.4 12.7 1.9 2 0 0 2 2 2 1 TLC domain Peptidase_M48 PF01435.13 CCH61824.1 - 5.9e-48 163.3 0.1 9.8e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 CCH61824.1 - 0.00032 20.1 0.0 0.0067 15.8 0.0 2.2 2 0 0 2 2 2 1 Predicted Zn-dependent protease (DUF2268) Peptidase_M56 PF05569.6 CCH61824.1 - 0.017 14.1 1.1 0.033 13.1 0.8 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 PCI PF01399.22 CCH61825.1 - 1.2e-20 73.7 1.3 2.3e-20 72.8 0.3 2.0 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CCH61825.1 - 1.1e-18 67.4 0.3 2.3e-18 66.3 0.2 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 CCH61825.1 - 0.015 15.1 0.4 0.053 13.2 0.1 2.1 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 zf-H2C2 PF09337.5 CCH61825.1 - 0.15 11.5 0.1 0.47 9.8 0.0 1.8 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Med17 PF10156.4 CCH61826.1 - 3e-120 401.6 20.6 7e-120 400.4 14.3 1.5 1 1 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.4 CCH61827.1 - 1.8e-42 144.6 9.9 2.4e-42 144.2 6.9 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 TFIIA PF03153.8 CCH61827.1 - 0.00024 21.1 7.8 0.00024 21.1 5.4 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spc97_Spc98 PF04130.8 CCH61827.1 - 0.048 11.9 1.6 0.064 11.5 1.1 1.1 1 0 0 1 1 1 0 Spc97 / Spc98 family CobT PF06213.7 CCH61827.1 - 0.052 12.6 14.6 0.063 12.3 10.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 CCH61827.1 - 0.51 8.5 3.5 0.54 8.4 2.4 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TRAP_alpha PF03896.11 CCH61827.1 - 0.61 9.0 10.6 0.85 8.5 7.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 CCH61827.1 - 1.7 8.2 20.2 2.1 7.9 14.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 CCH61827.1 - 1.8 6.4 12.7 2.1 6.2 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 CCH61827.1 - 2 7.5 19.5 2.5 7.2 13.5 1.1 1 0 0 1 1 1 0 NOA36 protein P5CR_dimer PF14748.1 CCH61828.1 - 4.7e-33 113.3 0.1 7.7e-33 112.7 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CCH61828.1 - 8.5e-10 38.9 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CCH61828.1 - 6.2e-05 22.7 0.3 0.00012 21.8 0.2 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 CCH61828.1 - 0.00039 19.8 0.3 0.0012 18.3 0.2 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ATP-synt_ab PF00006.20 CCH61829.1 - 6.6e-63 212.0 0.0 9.9e-63 211.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCH61829.1 - 2.7e-26 92.2 0.4 4.8e-26 91.4 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCH61829.1 - 1.1e-23 83.1 0.8 3e-23 81.8 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 CCH61829.1 - 0.00076 18.6 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 KaiC MobB PF03205.9 CCH61829.1 - 0.0051 16.5 0.1 0.54 9.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCH61829.1 - 0.0052 16.2 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCH61829.1 - 0.023 14.3 0.1 0.069 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 CCH61829.1 - 0.028 13.2 0.4 0.53 9.0 0.1 2.3 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.24 CCH61829.1 - 0.047 13.8 0.1 0.56 10.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCH61829.1 - 0.05 13.5 0.2 0.18 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CCH61829.1 - 0.056 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CCH61829.1 - 0.095 12.3 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 CCH61829.1 - 0.1 12.7 0.0 0.38 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCH61829.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Carn_acyltransf PF00755.15 CCH61830.1 - 2.2e-74 250.6 2.0 1.1e-63 215.2 0.3 2.2 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Zn_clus PF00172.13 CCH61831.1 - 1.3e-08 34.5 7.8 1.3e-08 34.5 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.6 CCH61832.1 - 3.7 7.3 7.5 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Fmp27_WPPW PF10359.4 CCH61833.1 - 6.8e-103 344.6 4.7 6.8e-103 344.6 3.3 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CCH61833.1 - 5.3e-78 262.9 12.8 7.1e-55 186.6 0.2 3.5 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27 PF10344.4 CCH61833.1 - 6.5e-67 225.9 71.3 4.3e-55 186.8 43.8 2.5 2 0 0 2 2 2 2 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.4 CCH61833.1 - 3.1e-53 179.8 1.5 3.8e-52 176.3 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCH61833.1 - 2e-47 160.8 2.9 2e-47 160.8 2.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCH61833.1 - 6.3e-30 103.6 0.7 3e-29 101.4 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ras PF00071.17 CCH61835.1 - 2.3e-54 183.1 0.0 2.7e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH61835.1 - 3.5e-16 59.7 0.0 5.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH61835.1 - 1.6e-08 34.0 0.0 2.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCH61835.1 - 0.0016 17.8 0.0 0.0075 15.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCH61835.1 - 0.038 13.1 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCH61835.1 - 0.057 12.6 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CCH61835.1 - 0.075 12.5 0.1 13 5.3 0.0 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.16 CCH61836.1 - 5.5e-19 67.2 0.2 9.2e-19 66.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.14 CCH61837.1 - 5.5e-38 130.5 0.0 6.9e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.27 CCH61838.1 - 2.1e-07 30.5 0.0 0.0038 17.0 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CCH61838.1 - 0.00071 19.7 0.1 2.8 8.3 0.0 3.5 3 0 0 3 3 3 2 PQQ-like domain PH_4 PF15404.1 CCH61839.1 - 3.3e-65 219.1 0.0 3.3e-65 219.1 0.0 3.7 4 0 0 4 4 4 1 Pleckstrin homology domain Spo7_2_N PF15407.1 CCH61839.1 - 3.7e-18 64.7 0.1 1.7e-17 62.5 0.1 2.3 1 0 0 1 1 1 1 Sporulation protein family 7 Rad51 PF08423.6 CCH61840.1 - 1.6e-124 413.8 0.2 2.8e-124 413.1 0.0 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CCH61840.1 - 2.5e-10 40.1 0.0 3.6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CCH61840.1 - 3.3e-08 32.9 0.1 1.5e-07 30.7 0.0 2.0 2 1 0 2 2 2 1 KaiC RecA PF00154.16 CCH61840.1 - 3.4e-08 32.9 0.0 4.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CCH61840.1 - 9.2e-06 25.7 0.4 3.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.6 CCH61840.1 - 0.028 13.2 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 PAXNEB protein RNA_pol_A_CTD PF03118.10 CCH61840.1 - 0.038 13.4 0.3 0.083 12.3 0.2 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA_22 PF13401.1 CCH61840.1 - 0.11 12.6 0.1 0.26 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain HTH_19 PF12844.2 CCH61840.1 - 0.15 12.1 0.3 8.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain Serinc PF03348.10 CCH61841.1 - 2.6e-149 497.6 15.6 3.2e-149 497.2 10.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) HGWP PF03578.10 CCH61841.1 - 0.033 13.5 0.5 0.079 12.2 0.3 1.7 1 0 0 1 1 1 0 HGWP repeat DUF1129 PF06570.6 CCH61841.1 - 1.9 7.7 14.5 0.14 11.4 3.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3302 PF11742.3 CCH61842.1 - 0.088 12.6 0.4 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) COX7C PF02935.11 CCH61842.1 - 2.5 7.9 6.4 27 4.6 4.4 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.11 CCH61843.1 - 1.4e-43 148.9 47.3 2.3e-43 148.2 32.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH61843.1 - 5.4e-14 51.6 15.7 5.4e-14 51.6 10.9 3.2 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 CCH61843.1 - 4.8e-06 25.0 20.3 7.3e-06 24.4 14.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NADH_dh_m_C1 PF15088.1 CCH61843.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial Sulfate_transp PF00916.15 CCH61844.1 - 1e-65 221.5 3.2 1e-65 221.5 2.2 2.3 2 1 1 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCH61844.1 - 1.3e-30 104.8 3.2 1.3e-30 104.8 2.2 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCH61844.1 - 1.9e-09 36.9 0.0 4.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCH61844.1 - 0.00075 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain Aminotran_1_2 PF00155.16 CCH61845.1 - 1.1e-38 133.1 0.0 1.6e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II rve PF00665.21 CCH61846.1 - 0.0075 16.3 0.0 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain Gaa1 PF04114.9 CCH61847.1 - 2.3e-119 399.3 17.9 1.1e-113 380.6 3.3 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component CcoS PF03597.10 CCH61847.1 - 3.2 7.3 5.9 0.61 9.5 0.1 2.6 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type GTP_EFTU PF00009.22 CCH61848.1 - 2.5e-57 193.3 0.1 3.4e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCH61848.1 - 5.4e-34 116.3 0.0 1.3e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCH61848.1 - 2.9e-16 59.3 1.5 2.9e-16 59.3 1.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCH61848.1 - 9.1e-05 22.0 0.4 9.1e-05 22.0 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCH61848.1 - 0.00073 19.4 0.2 0.002 18.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase tRNA-synt_2b PF00587.20 CCH61850.1 - 7.8e-64 214.4 0.1 1.3e-63 213.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH61850.1 - 7.8e-21 73.8 0.1 2.1e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain Tau95 PF09734.4 CCH61851.1 - 2e-63 214.5 5.6 2e-63 214.5 3.9 2.0 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit PP2C PF00481.16 CCH61852.1 - 7.4e-65 218.8 0.0 6.7e-59 199.3 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCH61852.1 - 3e-07 30.0 0.0 3.2e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CCH61852.1 - 0.0017 18.1 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Glyco_transf_20 PF00982.16 CCH61853.1 - 2.5e-202 672.5 0.0 2.9e-202 672.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CCH61853.1 - 2.2e-05 23.9 0.4 0.012 15.0 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCH61853.1 - 0.0098 16.0 0.0 0.024 14.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Retrotrans_gag PF03732.12 CCH61854.1 - 7e-14 51.6 0.1 2.1e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Ras PF00071.17 CCH61855.1 - 0.00021 20.7 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Ras family AAA_16 PF13191.1 CCH61855.1 - 0.00047 20.1 0.4 0.0014 18.6 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 CCH61855.1 - 0.0048 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCH61855.1 - 0.012 16.1 0.0 0.049 14.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 CCH61855.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCH61855.1 - 0.018 15.1 0.0 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCH61855.1 - 0.034 13.6 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCH61855.1 - 0.04 14.2 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CCH61855.1 - 0.04 12.6 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit DUF87 PF01935.12 CCH61855.1 - 0.2 11.4 0.3 0.53 10.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 SUKH-4 PF14435.1 CCH61856.1 - 0.033 13.9 0.0 0.63 9.7 0.0 2.3 2 0 0 2 2 2 0 SUKH-4 immunity protein RVT_2 PF07727.9 CCH61857.1 - 1.1e-75 253.8 0.0 1.3e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 CCH61857.1 - 0.041 13.2 0.2 0.1 11.9 0.1 1.6 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) PH PF00169.24 CCH61858.1 - 3e-05 24.1 5.1 0.0024 18.0 0.1 3.3 3 1 0 3 3 3 2 PH domain PH_11 PF15413.1 CCH61858.1 - 0.012 15.8 11.6 0.081 13.1 0.2 4.1 3 1 1 4 4 4 0 Pleckstrin homology domain HALZ PF02183.13 CCH61859.1 - 0.13 11.9 23.3 0.46 10.2 1.8 4.7 4 1 1 5 5 5 0 Homeobox associated leucine zipper Hemerythrin PF01814.18 CCH61859.1 - 0.61 10.2 7.8 1.2 9.3 0.4 2.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain BRCA-2_OB3 PF09104.5 CCH61859.1 - 5.4 6.8 8.3 3.7 7.3 0.4 3.1 2 1 1 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 SRP54 PF00448.17 CCH61860.1 - 6.2e-81 270.5 3.3 5.6e-80 267.4 0.6 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CCH61860.1 - 4.2e-26 91.2 11.4 4.2e-26 91.2 7.9 4.8 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 CCH61860.1 - 2.7e-14 52.9 2.5 8.9e-14 51.3 1.7 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CCH61860.1 - 1.6e-06 27.7 2.6 1e-05 25.0 0.5 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.1 CCH61860.1 - 3.8e-06 26.9 0.8 0.038 13.9 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 CCH61860.1 - 1.1e-05 25.2 0.0 3.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CCH61860.1 - 3.3e-05 23.5 0.1 9.6e-05 22.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 CCH61860.1 - 4.3e-05 23.0 1.7 9.4e-05 21.8 0.2 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.5 CCH61860.1 - 0.00019 20.7 5.1 0.66 9.1 0.0 4.2 3 1 1 4 4 4 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 CCH61860.1 - 0.001 19.8 0.0 0.002 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCH61860.1 - 0.0011 18.4 0.4 0.0027 17.2 0.2 1.6 1 1 0 1 1 1 1 AAA-like domain APS_kinase PF01583.15 CCH61860.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 CCH61860.1 - 0.014 15.5 0.5 0.097 12.8 0.1 2.8 2 1 0 2 2 1 0 AAA domain SIS_2 PF13580.1 CCH61860.1 - 0.015 14.9 0.3 0.084 12.5 0.1 2.4 2 0 0 2 2 2 0 SIS domain MipZ PF09140.6 CCH61860.1 - 0.017 14.1 2.1 0.21 10.6 0.1 2.9 2 1 0 2 2 2 0 ATPase MipZ ArgK PF03308.11 CCH61860.1 - 0.017 13.8 2.8 0.024 13.4 0.1 2.7 3 1 0 3 3 3 0 ArgK protein AAA_18 PF13238.1 CCH61860.1 - 0.02 15.2 0.1 0.086 13.1 0.0 2.3 2 1 0 2 2 1 0 AAA domain VirE PF05272.6 CCH61860.1 - 0.035 13.5 0.1 0.096 12.1 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E Glyco_trans_4_2 PF13477.1 CCH61860.1 - 0.047 13.5 0.1 0.28 10.9 0.0 2.3 3 0 0 3 3 3 0 Glycosyl transferase 4-like DDE_Tnp_1_3 PF13612.1 CCH61860.1 - 0.061 13.0 1.0 0.16 11.7 0.7 1.7 1 0 0 1 1 1 0 Transposase DDE domain Zeta_toxin PF06414.7 CCH61860.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CCH61860.1 - 0.085 12.8 0.0 0.68 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 CCH61860.1 - 0.1 11.7 4.2 0.87 8.7 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 CCH61860.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CCH61860.1 - 0.15 11.4 0.1 0.44 9.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CCH61860.1 - 0.56 10.3 8.1 0.76 9.9 1.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Aa_trans PF01490.13 CCH61861.1 - 3e-85 286.1 32.5 3.5e-85 285.9 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4611 PF15387.1 CCH61861.1 - 0.46 10.6 3.4 0.96 9.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) AA_permease PF00324.16 CCH61862.1 - 1.6e-115 386.1 32.5 2e-115 385.8 22.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH61862.1 - 5.6e-19 67.9 35.4 7e-19 67.6 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease PI3_PI4_kinase PF00454.22 CCH61863.1 - 7.5e-47 159.7 0.5 2.3e-46 158.1 0.4 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CCH61863.1 - 1.3e-23 82.9 0.5 8.8e-23 80.3 0.4 2.6 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 CCH61863.1 - 2.4e-14 52.4 0.3 5.1e-14 51.4 0.2 1.5 1 0 0 1 1 1 1 FATC domain Endonuc-dimeris PF09124.5 CCH61863.1 - 0.046 13.3 0.1 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation TPR_19 PF14559.1 CCH61863.1 - 0.13 12.6 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.4 CCH61863.1 - 0.39 10.6 0.2 1 9.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2404 PF10296.4 CCH61864.1 - 2.1e-29 101.5 0.1 5.3e-29 100.1 0.0 1.8 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CCH61864.1 - 1.5e-07 31.5 5.1 1.5e-07 31.5 3.5 3.1 2 2 0 2 2 2 1 PH domain PH_11 PF15413.1 CCH61864.1 - 4.3e-06 26.9 0.5 4.3e-06 26.9 0.3 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain Cofilin_ADF PF00241.15 CCH61865.1 - 2.5e-25 88.8 3.4 4.4e-13 49.2 0.4 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Fib_alpha PF08702.5 CCH61865.1 - 0.25 11.4 3.8 5.1 7.2 0.0 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FAINT PF04385.10 CCH61865.1 - 0.71 9.7 9.2 0.047 13.5 1.6 2.7 3 0 0 3 3 3 0 Domain of unknown function, DUF529 zf-RING_2 PF13639.1 CCH61866.1 - 1.7e-09 37.3 7.1 1.7e-09 37.3 5.0 3.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 CCH61866.1 - 1.4e-07 31.0 6.8 1.4e-07 31.0 4.7 3.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH61866.1 - 4.7e-06 26.5 7.2 4.7e-06 26.5 5.0 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCH61866.1 - 1.1e-05 25.4 9.0 1.1e-05 25.4 6.3 3.4 3 1 0 3 3 3 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCH61866.1 - 0.0002 21.0 2.7 0.0002 21.0 1.9 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CCH61866.1 - 0.00099 18.7 4.4 0.00099 18.7 3.1 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH61866.1 - 0.0068 16.2 4.6 0.0068 16.2 3.2 3.8 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING PHD PF00628.24 CCH61866.1 - 0.011 15.3 7.4 0.011 15.3 5.1 3.1 3 0 0 3 3 3 0 PHD-finger zf-Nse PF11789.3 CCH61866.1 - 3.5 7.2 10.4 0.2 11.2 2.8 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PHF5 PF03660.9 CCH61867.1 - 1.7e-42 143.8 11.9 1.9e-42 143.6 8.2 1.0 1 0 0 1 1 1 1 PHF5-like protein Ribosomal_S14 PF00253.16 CCH61867.1 - 0.053 12.9 3.6 0.14 11.6 2.4 1.9 1 1 0 1 1 1 0 Ribosomal protein S14p/S29e NMD3 PF04981.8 CCH61867.1 - 8.8 5.3 12.9 5.4 6.0 3.3 2.2 2 0 0 2 2 2 0 NMD3 family Sec7 PF01369.15 CCH61868.1 - 3.3e-33 114.9 1.3 1.7e-32 112.6 0.9 2.3 1 0 0 1 1 1 1 Sec7 domain HIM1 PF08732.5 CCH61869.1 - 8.4e-08 31.0 0.1 2.6e-06 26.1 0.0 1.9 1 1 1 2 2 2 2 HIM1 NAD_binding_10 PF13460.1 CCH61869.1 - 0.003 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Proteasom_Rpn13 PF04683.8 CCH61870.1 - 1.6e-18 66.5 0.0 2.3e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2262 PF10020.4 CCH61870.1 - 0.019 15.1 1.3 0.031 14.4 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Ded_cyto PF06920.8 CCH61871.1 - 1.5e-16 60.2 0.0 5.8e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis CHCH PF06747.8 CCH61872.1 - 2.5e-08 33.5 3.9 5.6e-08 32.5 2.7 1.6 1 0 0 1 1 1 1 CHCH domain DUF1926 PF09095.6 CCH61872.1 - 0.0029 16.8 0.6 0.0098 15.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1926) GCK PF07802.6 CCH61872.1 - 0.038 14.0 2.4 0.098 12.7 1.7 1.6 1 0 0 1 1 1 0 GCK domain Longin PF13774.1 CCH61873.1 - 5.1e-16 57.9 0.0 7.9e-16 57.3 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCH61873.1 - 1.5e-14 53.3 1.3 2.4e-14 52.6 0.9 1.3 1 0 0 1 1 1 1 Synaptobrevin SUR7 PF06687.7 CCH61874.1 - 1.6e-20 73.6 4.9 2e-19 70.0 3.4 2.2 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CCH61874.1 - 0.018 14.8 14.9 0.014 15.2 6.9 2.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4512 PF14975.1 CCH61874.1 - 0.17 12.7 4.9 0.72 10.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4512) Rif1_N PF12231.3 CCH61875.1 - 2e-26 92.8 17.3 2e-26 92.8 12.0 3.1 3 1 0 3 3 3 2 Rap1-interacting factor 1 N terminal SHMT PF00464.14 CCH61876.1 - 6e-192 637.3 0.0 7.1e-192 637.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Methyltransf_PK PF05891.7 CCH61878.1 - 5.3e-92 307.0 0.0 6e-92 306.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 CCH61878.1 - 1.1e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH61878.1 - 0.0084 16.5 0.0 0.02 15.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH61878.1 - 0.0084 16.6 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.7 CCH61878.1 - 0.038 13.9 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) RrnaAD PF00398.15 CCH61878.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RhoGAP PF00620.22 CCH61879.1 - 1.4e-19 70.1 0.0 1.4e-19 70.1 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CCH61879.1 - 0.00023 21.2 0.4 0.00023 21.2 0.3 3.7 2 1 1 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1027 PF06265.6 CCH61879.1 - 0.0057 16.4 0.9 0.024 14.4 0.7 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1027) Cullin PF00888.17 CCH61880.1 - 1.8e-10 39.9 23.6 1.8e-10 39.9 16.4 1.9 2 0 0 2 2 2 1 Cullin family BPL_LplA_LipB PF03099.14 CCH61882.1 - 1.5e-12 47.6 0.1 7.8e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DUF4183 PF13799.1 CCH61882.1 - 0.012 15.4 0.1 0.04 13.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) Abhydrolase_6 PF12697.2 CCH61883.1 - 8e-19 68.4 0.0 2.3e-18 66.9 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH61883.1 - 7.2e-15 55.1 0.3 1.4e-14 54.1 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCH61883.1 - 9.9e-11 41.5 0.0 2.2e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 CCH61883.1 - 0.00028 20.3 0.0 0.00056 19.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 CCH61883.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.8 CCH61883.1 - 0.0038 16.8 0.0 0.0065 16.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.3 CCH61883.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase tRNA-synt_2 PF00152.15 CCH61884.1 - 1e-75 254.6 0.0 1.5e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCH61884.1 - 4.9e-11 42.3 0.3 9.5e-11 41.4 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 CCH61884.1 - 0.025 14.0 0.4 0.044 13.2 0.2 1.3 1 0 0 1 1 1 0 tRNA_anti-like Ins134_P3_kin PF05770.6 CCH61884.1 - 0.084 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Lyase_1 PF00206.15 CCH61885.1 - 5.8e-94 314.7 0.0 8.5e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CCH61885.1 - 1.3e-24 86.0 0.1 4.4e-24 84.3 0.0 2.0 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal DUF500 PF04366.7 CCH61886.1 - 2.3e-45 153.0 0.2 4e-45 152.3 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCH61886.1 - 6e-17 60.7 0.0 1.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH61886.1 - 4.5e-15 54.9 0.0 9.3e-15 53.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH61886.1 - 4.3e-13 48.5 0.1 8.4e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 CCH61887.1 - 6.9e-21 73.6 16.9 1.7e-10 40.3 0.9 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH61887.1 - 5.1e-11 42.3 3.8 0.00017 21.5 0.1 4.5 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH61887.1 - 4.7e-08 32.7 10.7 1.3e-06 28.1 1.6 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YagB_YeeU_YfjZ PF06154.6 CCH61887.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 YagB/YeeU/YfjZ family RVT_2 PF07727.9 CCH61890.1 - 4.4e-56 189.5 0.6 7e-56 188.9 0.4 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cation_ATPase_C PF00689.16 CCH61891.1 - 0.35 10.3 3.6 0.63 9.5 2.5 1.4 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Zn_clus PF00172.13 CCH61892.1 - 0.0011 18.8 15.1 0.0019 18.0 2.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind_2 PF13725.1 CCH61892.1 - 0.091 12.8 0.8 0.43 10.6 0.4 2.3 1 1 1 2 2 2 0 Possible tRNA binding domain Cohesin_load PF10345.4 CCH61893.1 - 4.4e-33 114.3 68.0 4.1e-32 111.2 47.1 2.4 1 1 0 1 1 1 1 Cohesin loading factor Glyco_transf_20 PF00982.16 CCH61894.1 - 4e-144 480.6 3.8 5.4e-144 480.1 2.6 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCH61894.1 - 4.4e-80 267.9 0.0 7.9e-80 267.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Dna2 PF08696.6 CCH61894.1 - 0.014 14.7 0.7 0.14 11.4 0.1 2.4 2 0 0 2 2 2 0 DNA replication factor Dna2 HAD PF12710.2 CCH61894.1 - 0.18 11.9 1.1 12 6.0 0.2 2.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PAP2 PF01569.16 CCH61896.1 - 2.6e-05 23.9 0.7 2.6e-05 23.9 0.5 3.4 3 1 0 3 3 3 2 PAP2 superfamily Tetraspannin PF00335.15 CCH61896.1 - 0.31 10.2 8.4 0.8 8.9 5.8 1.6 1 0 0 1 1 1 0 Tetraspanin family DUF418 PF04235.7 CCH61896.1 - 9.8 5.8 12.4 6.6 6.3 0.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF418) Acetyltransf_1 PF00583.19 CCH61897.1 - 2.4e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCH61897.1 - 6.6e-09 35.8 0.0 9.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCH61897.1 - 0.0022 17.9 0.2 0.0054 16.6 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCH61897.1 - 0.0089 15.8 0.0 0.07 12.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCH61897.1 - 0.014 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FMN_bind PF04205.9 CCH61897.1 - 0.057 13.5 0.1 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 FMN-binding domain FR47 PF08445.5 CCH61897.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Phage_antitermQ PF06530.7 CCH61897.1 - 0.13 11.8 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q UCH PF00443.24 CCH61898.1 - 1.2e-68 231.1 2.6 1.2e-68 231.1 1.8 2.9 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH61898.1 - 3.2e-30 105.5 0.9 3.2e-30 105.5 0.6 3.8 2 1 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCH61898.1 - 0.0011 19.3 0.4 0.017 15.4 0.3 2.5 1 1 0 1 1 1 1 Rhodanese-like domain BSD PF03909.12 CCH61899.1 - 2.6e-15 55.9 1.4 4.8e-15 55.0 0.2 2.1 2 0 0 2 2 2 1 BSD domain DUF1890 PF09001.6 CCH61899.1 - 0.16 11.9 3.3 0.46 10.4 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1890) HhH-GPD PF00730.20 CCH61900.1 - 1.3e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RPAP2_Rtr1 PF04181.8 CCH61901.1 - 4.9e-15 55.3 1.0 1.5e-14 53.8 0.7 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family EutQ PF06249.7 CCH61902.1 - 0.06 12.8 1.4 0.29 10.6 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation protein EutQ TMF_TATA_bd PF12325.3 CCH61903.1 - 0.011 15.4 4.3 0.013 15.2 3.0 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CR6_interact PF10147.4 CCH61903.1 - 0.027 13.7 1.5 0.031 13.5 1.0 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Microtub_assoc PF07989.6 CCH61903.1 - 0.16 11.7 3.3 0.093 12.5 0.6 1.7 1 1 1 2 2 2 0 Microtubule associated Sec34 PF04136.10 CCH61904.1 - 1.3e-21 76.9 11.4 1.3e-21 76.9 7.9 4.0 4 1 0 4 4 4 1 Sec34-like family Med27 PF11571.3 CCH61904.1 - 7.3 6.7 8.9 0.41 10.7 0.2 3.5 4 0 0 4 4 4 0 Mediator complex subunit 27 DDE_1 PF03184.14 CCH61905.1 - 8.2e-71 237.5 14.2 3.3e-70 235.6 9.8 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CCH61905.1 - 1e-12 47.6 0.7 2.8e-12 46.2 0.5 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Stn1 PF10451.4 CCH61906.1 - 6.3e-21 74.3 1.1 1.8e-20 72.8 0.8 1.8 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 CCH61906.1 - 0.0011 18.7 4.2 0.0011 18.7 2.9 2.9 2 1 1 3 3 3 1 Telomere capping C-terminal wHTH tRNA_bind_2 PF13725.1 CCH61906.1 - 0.019 15.0 0.3 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Possible tRNA binding domain gp37_C PF12604.3 CCH61906.1 - 0.022 14.5 0.2 0.065 13.0 0.1 1.7 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal Slu7 PF11708.3 CCH61908.1 - 4.2e-39 134.7 13.7 4.2e-39 134.7 9.5 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor PHD PF00628.24 CCH61908.1 - 0.049 13.3 0.6 0.12 12.0 0.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-CCHC PF00098.18 CCH61908.1 - 0.11 12.4 1.8 0.26 11.2 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCH61908.1 - 0.16 11.6 0.8 0.43 10.2 0.6 1.8 1 0 0 1 1 1 0 Zinc knuckle Zn_clus PF00172.13 CCH61909.1 - 0.00025 20.8 12.0 0.00025 20.8 8.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPT2 PF08243.6 CCH61910.1 - 1e-27 96.7 29.0 1e-27 96.7 20.1 3.1 3 0 0 3 3 3 1 SPT2 chromatin protein Sigma70_r3 PF04539.11 CCH61910.1 - 0.03 14.2 0.7 0.093 12.6 0.5 1.9 1 0 0 1 1 1 0 Sigma-70 region 3 ABC_tran PF00005.22 CCH61911.1 - 1.3e-34 119.4 0.0 3.8e-16 59.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 CCH61911.1 - 8e-15 54.1 6.0 2.2e-14 52.7 4.2 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CCH61911.1 - 7.5e-13 49.0 9.4 0.0057 16.6 0.0 4.2 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 CCH61911.1 - 5.1e-10 38.9 2.0 0.0033 16.6 0.2 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCH61911.1 - 1.3e-07 31.0 2.9 0.39 9.7 0.0 4.2 3 1 1 4 4 4 3 AAA ATPase domain Fer4 PF00037.22 CCH61911.1 - 2.4e-07 30.0 3.8 2.4e-07 30.0 2.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.24 CCH61911.1 - 2.1e-06 27.9 0.0 0.008 16.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCH61911.1 - 3.3e-06 26.3 1.0 0.027 13.6 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCH61911.1 - 1.1e-05 25.5 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CCH61911.1 - 2.3e-05 23.7 0.4 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCH61911.1 - 2.7e-05 24.2 0.0 0.026 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH61911.1 - 9.3e-05 23.2 0.6 0.41 11.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain Fer4_6 PF12837.2 CCH61911.1 - 0.00022 20.9 12.3 0.00038 20.2 2.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Miro PF08477.8 CCH61911.1 - 0.00023 21.6 0.2 1.3 9.5 0.0 2.8 2 1 0 3 3 2 2 Miro-like protein Fer4_7 PF12838.2 CCH61911.1 - 0.00025 21.3 0.4 0.00025 21.3 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.1 CCH61911.1 - 0.00048 20.4 0.4 1.8 8.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCH61911.1 - 0.00056 18.8 0.1 0.12 11.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_21 PF14697.1 CCH61911.1 - 0.00077 19.2 11.7 0.0017 18.1 8.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_25 PF13481.1 CCH61911.1 - 0.00095 18.6 0.1 0.84 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CCH61911.1 - 0.0023 17.6 0.9 0.55 9.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_2 PF12797.2 CCH61911.1 - 0.0026 17.5 2.4 0.0026 17.5 1.7 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.17 CCH61911.1 - 0.0032 17.5 0.1 1.3 9.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CCH61911.1 - 0.0036 17.2 0.2 1.7 8.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain VirE PF05272.6 CCH61911.1 - 0.004 16.6 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E NACHT PF05729.7 CCH61911.1 - 0.0044 16.7 1.8 0.33 10.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Fer4_9 PF13187.1 CCH61911.1 - 0.0049 17.0 2.2 0.0049 17.0 1.5 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_33 PF13671.1 CCH61911.1 - 0.0057 16.5 0.3 1.2 8.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain Fer4_3 PF12798.2 CCH61911.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.6 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_16 PF13484.1 CCH61911.1 - 0.006 17.2 0.1 0.006 17.2 0.1 2.6 2 1 1 3 3 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 CCH61911.1 - 0.0076 16.0 1.4 0.0076 16.0 1.0 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.17 CCH61911.1 - 0.0078 15.6 3.0 0.31 10.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CCH61911.1 - 0.011 15.5 0.6 2.8 7.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 CCH61911.1 - 0.012 14.3 0.0 1 7.9 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 CCH61911.1 - 0.016 14.8 0.1 0.4 10.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 CCH61911.1 - 0.018 14.9 0.2 14 5.6 0.0 3.7 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 CCH61911.1 - 0.032 13.9 1.1 0.28 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CCH61911.1 - 0.036 13.6 0.2 0.86 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 CCH61911.1 - 0.042 14.2 2.2 0.042 14.2 1.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain T2SE PF00437.15 CCH61911.1 - 0.049 12.5 0.2 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Fer4_17 PF13534.1 CCH61911.1 - 0.086 13.2 0.2 0.086 13.2 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.18 CCH61911.1 - 0.09 12.7 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.12 CCH61911.1 - 0.11 11.8 1.5 10 5.4 0.1 3.3 4 0 0 4 4 3 0 Thymidylate kinase PduV-EutP PF10662.4 CCH61911.1 - 0.13 11.7 1.5 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CCH61911.1 - 0.14 11.0 0.0 5.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 CCH61911.1 - 0.14 10.8 0.1 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Fer4_8 PF13183.1 CCH61911.1 - 0.18 11.8 8.3 0.092 12.7 0.7 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 CCH61911.1 - 0.19 11.2 1.7 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCH61911.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 CCH61911.1 - 1.8 6.9 0.0 1.8 6.9 0.0 2.8 5 0 0 5 5 5 0 AAA domain SNF2_N PF00176.18 CCH61912.1 - 1.4e-75 253.8 0.2 1.4e-75 253.8 0.1 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCH61912.1 - 1.8e-27 95.4 0.2 1.8e-27 95.4 0.1 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CCH61912.1 - 1.7e-19 69.2 1.4 4e-12 45.6 0.1 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CCH61912.1 - 5.5e-15 54.9 0.2 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 CCH61913.1 - 6.7e-88 288.3 5.9 9.1e-23 79.6 0.2 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH61913.1 - 8.7e-64 211.4 0.1 6e-17 61.3 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH61913.1 - 6.4e-47 157.2 1.6 3.2e-11 42.8 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCH61913.1 - 1e-22 79.5 1.2 1.1e-21 76.2 0.1 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CCH61913.1 - 1.5e-07 31.1 4.1 0.051 13.4 0.7 4.6 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 CCH61913.1 - 0.0021 17.7 0.2 8 6.3 0.0 3.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 CCH61913.1 - 0.011 15.9 0.1 0.95 9.7 0.0 2.8 2 0 0 2 2 2 0 Cobalamin biosynthesis central region YflT PF11181.3 CCH61913.1 - 0.019 15.0 4.4 0.95 9.6 0.3 3.5 3 0 0 3 3 3 0 Heat induced stress protein YflT Limkain-b1 PF11608.3 CCH61913.1 - 0.056 13.2 0.9 29 4.5 0.0 3.9 4 0 0 4 4 4 0 Limkain b1 Peptidase_C26 PF07722.8 CCH61913.1 - 0.088 12.2 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase C26 OB_RNB PF08206.6 CCH61913.1 - 0.17 11.3 8.5 7.7 6.0 0.2 3.7 3 1 0 3 3 3 0 Ribonuclease B OB domain PNPase PF03726.9 CCH61913.1 - 0.69 10.2 4.0 1.3 9.3 0.0 3.1 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain UQ_con PF00179.21 CCH61914.1 - 1.8e-46 157.0 0.0 2.1e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH61914.1 - 0.00041 20.1 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCH61914.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CCH61914.1 - 0.013 15.3 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain E1-E2_ATPase PF00122.15 CCH61915.1 - 7.9e-16 57.7 0.0 1.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCH61915.1 - 9.6e-14 51.9 0.1 2.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH61915.1 - 1.6e-12 47.2 0.0 4.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CCH61915.1 - 7.5e-10 39.5 2.7 2e-05 25.1 1.3 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCH61915.1 - 0.0037 16.8 0.2 0.0037 16.8 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Methyltransf_12 PF08242.7 CCH61916.1 - 2.9 8.4 7.5 1.9 8.9 0.1 3.0 2 0 0 2 2 2 0 Methyltransferase domain JmjC PF02373.17 CCH61917.1 - 4.6e-08 33.2 0.2 2e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-H2C2_2 PF13465.1 CCH61917.1 - 5.7e-08 32.6 11.1 4.3e-07 29.8 4.7 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCH61917.1 - 4.4e-07 29.8 16.9 0.0011 19.1 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH61917.1 - 3.9e-06 26.8 13.1 0.0015 18.7 1.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCH61917.1 - 0.0034 17.2 10.0 0.019 14.8 2.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCH61917.1 - 0.11 12.6 11.1 0.21 11.7 3.3 2.6 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CCH61917.1 - 1.2 9.1 6.3 5.7 6.9 4.3 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.2 CCH61917.1 - 8.7 6.7 9.0 28 5.0 0.5 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MutS_V PF00488.16 CCH61918.1 - 3.9e-76 255.5 0.0 7e-76 254.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCH61918.1 - 1.6e-40 139.1 0.4 3.5e-40 137.9 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCH61918.1 - 1.9e-32 111.6 0.0 7.8e-32 109.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CCH61918.1 - 1.9e-14 53.5 0.2 4.9e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CCH61918.1 - 1.7e-10 41.1 0.1 6.2e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 CCH61918.1 - 0.063 12.8 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADK PF00406.17 CCH61919.1 - 1.2e-44 151.7 0.0 1.5e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCH61919.1 - 5.8e-13 48.2 0.0 9.2e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 CCH61919.1 - 5.2e-07 30.0 0.0 1.1e-06 28.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCH61919.1 - 6e-06 26.1 0.0 1.3e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH61919.1 - 0.001 19.8 0.0 0.0018 19.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCH61919.1 - 0.0048 16.0 0.0 0.022 13.8 0.0 1.9 1 1 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 CCH61919.1 - 0.11 12.2 0.8 0.25 11.0 0.2 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCH61919.1 - 0.15 11.2 0.1 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glutaredoxin PF00462.19 CCH61920.1 - 2.6e-19 68.9 0.2 1.1e-17 63.7 0.0 2.8 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.15 CCH61920.1 - 1.7e-14 53.3 0.0 3.5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCH61920.1 - 1.3e-05 25.2 0.1 0.0011 19.1 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CCH61920.1 - 2.2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CCH61920.1 - 0.0065 16.6 0.1 0.13 12.5 0.0 2.8 1 1 1 2 2 2 1 Thioredoxin-like domain TrbC_Ftype PF09673.5 CCH61920.1 - 0.015 14.9 0.0 0.062 12.9 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Redoxin PF08534.5 CCH61920.1 - 0.024 14.1 0.0 0.065 12.7 0.0 1.6 1 1 1 2 2 2 0 Redoxin Adenine_glyco PF03352.8 CCH61920.1 - 0.051 13.0 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyladenine glycosylase Myc_N PF01056.13 CCH61920.1 - 0.076 12.1 2.4 0.095 11.8 1.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Thioredoxin_7 PF13899.1 CCH61920.1 - 0.13 12.2 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like Tom22 PF04281.8 CCH61920.1 - 0.15 11.6 3.1 0.24 10.9 2.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PP1c_bdg PF10488.4 CCH61920.1 - 0.27 10.4 4.0 0.36 9.9 2.8 1.1 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region Methyltransf_12 PF08242.7 CCH61921.1 - 1.5e-08 34.9 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCH61921.1 - 1.8e-08 34.7 0.0 3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH61921.1 - 2.6e-08 33.7 0.0 3.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH61921.1 - 2.8e-08 33.5 0.0 4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH61921.1 - 1.5e-07 31.6 0.1 2.7e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH61921.1 - 9.1e-05 23.0 0.0 0.00016 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCH61921.1 - 0.00074 18.7 0.1 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 CCH61921.1 - 0.0098 15.2 0.0 0.045 13.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 CCH61921.1 - 0.084 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 14-3-3 PF00244.15 CCH61922.1 - 8.9e-114 378.4 6.2 1.1e-113 378.1 4.3 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.6 CCH61922.1 - 0.009 15.8 0.2 0.03 14.2 0.1 1.8 1 0 0 1 1 1 1 Flagellar protein FlaF COPI_assoc PF08507.5 CCH61923.1 - 3.4e-27 94.8 4.0 4.1e-27 94.5 2.8 1.1 1 0 0 1 1 1 1 COPI associated protein E1_dh PF00676.15 CCH61924.1 - 5.3e-119 396.3 0.2 9.3e-119 395.5 0.0 1.4 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CCH61924.1 - 0.0045 15.9 0.2 0.011 14.6 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 CCH61924.1 - 0.16 12.6 5.7 0.23 12.1 0.2 2.9 2 2 0 2 2 2 0 KRTAP type 7 family Serglycin PF04360.7 CCH61925.1 - 0.82 9.3 11.0 1.7 8.3 7.6 1.4 1 0 0 1 1 1 0 Serglycin zf-RING_2 PF13639.1 CCH61925.1 - 1.2 9.0 8.6 0.05 13.4 1.4 2.1 2 0 0 2 2 2 0 Ring finger domain BUD22 PF09073.5 CCH61926.1 - 5.1e-75 253.1 53.8 1.2e-61 209.0 24.2 2.2 1 1 1 2 2 2 2 BUD22 LAGLIDADG_WhiA PF14527.1 CCH61926.1 - 8.9 6.2 9.6 18 5.2 1.9 3.4 2 1 1 3 3 3 0 WhiA LAGLIDADG-like domain DUF2347 PF09804.4 CCH61928.1 - 1.3e-70 237.8 0.6 1.9e-70 237.3 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 CCH61928.1 - 4.2e-12 46.5 2.1 7.1e-07 29.4 0.3 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 CCH61928.1 - 8e-11 41.0 0.2 1.8e-06 26.6 0.0 2.7 1 1 1 3 3 3 2 Transport protein Avl9 SPA PF08616.5 CCH61928.1 - 0.00019 21.0 0.1 0.00048 19.7 0.1 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 CCH61928.1 - 0.021 14.8 0.1 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking VWA_N PF08399.6 CCH61928.1 - 0.096 13.2 3.2 0.28 11.7 0.2 2.5 2 0 0 2 2 2 0 VWA N-terminal dsrm PF00035.20 CCH61929.1 - 7e-07 29.7 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CCH61929.1 - 1.2e-06 28.9 0.1 4.1e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain Tim17 PF02466.14 CCH61930.1 - 1.2e-28 99.6 3.0 1.6e-28 99.2 2.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_S8 PF00082.17 CCH61931.1 - 5.6e-44 150.3 0.7 5.6e-44 150.3 0.5 2.3 2 1 0 2 2 2 1 Subtilase family WBS_methylT PF12589.3 CCH61932.1 - 8.8e-16 58.1 4.2 1.9e-15 57.0 2.9 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CCH61932.1 - 2.3e-12 47.2 0.0 4.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH61932.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCH61932.1 - 5.6e-07 29.2 0.0 1.7e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH61932.1 - 1.6e-06 28.3 0.0 4.2e-06 27.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH61932.1 - 4.1e-06 27.1 0.1 4.4e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH61932.1 - 0.00015 22.2 0.0 0.0005 20.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCH61932.1 - 0.00029 20.4 0.0 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 CCH61932.1 - 0.0009 19.2 0.0 0.0033 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCH61932.1 - 0.0029 16.7 0.0 0.02 14.0 0.0 2.0 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 CCH61932.1 - 0.0034 17.5 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MetW PF07021.7 CCH61932.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N6_N4_Mtase PF01555.13 CCH61932.1 - 0.015 14.7 0.1 0.33 10.4 0.0 2.3 2 1 0 2 2 2 0 DNA methylase PrmA PF06325.8 CCH61932.1 - 0.029 13.5 0.1 0.069 12.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 CCH61932.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MBOAT PF03062.14 CCH61933.1 - 6.3e-56 189.8 46.6 1.5e-55 188.5 32.3 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CCH61933.1 - 0.00019 21.4 5.9 0.00054 19.9 4.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_M76 PF09768.4 CCH61934.1 - 1.6e-73 245.8 1.3 2.7e-73 245.0 0.9 1.4 1 1 0 1 1 1 1 Peptidase M76 family Peptidase_MA_2 PF13485.1 CCH61934.1 - 0.021 14.8 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily SprT-like PF10263.4 CCH61934.1 - 0.34 10.5 2.6 0.22 11.1 0.3 1.8 1 1 0 2 2 2 0 SprT-like family Ank_5 PF13857.1 CCH61935.1 - 9.3e-19 67.0 0.4 1e-13 51.0 0.5 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCH61935.1 - 6.3e-14 52.0 3.9 3e-08 33.9 0.3 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCH61935.1 - 1.8e-12 47.4 0.3 1.4e-11 44.5 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCH61935.1 - 7.6e-10 38.0 0.5 0.0001 22.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CCH61935.1 - 1e-09 37.6 1.4 7.5e-07 28.6 0.3 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF1682 PF07946.9 CCH61936.1 - 6.4e-76 255.2 9.8 8.2e-76 254.8 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4375 PF14300.1 CCH61936.1 - 0.014 15.3 2.2 0.021 14.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) GCD14 PF08704.5 CCH61936.1 - 0.13 11.7 5.6 0.22 10.9 3.7 1.5 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ribosomal_L9_N PF01281.14 CCH61937.1 - 0.027 13.6 0.0 0.08 12.2 0.0 1.9 1 1 0 1 1 1 0 Ribosomal protein L9, N-terminal domain Thr_synth_N PF14821.1 CCH61938.1 - 1.1e-25 89.3 0.0 3.8e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 CCH61938.1 - 7.2e-20 71.4 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.4 CCH61939.1 - 5.6e-39 131.9 5.1 2.2e-38 130.0 1.1 2.7 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Fork_head PF00250.13 CCH61940.1 - 3.5e-34 116.7 0.6 3.5e-34 116.7 0.4 2.5 2 0 0 2 2 2 1 Fork head domain WD40 PF00400.27 CCH61941.1 - 2.5e-06 27.1 0.1 0.0015 18.3 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Pro_isomerase PF00160.16 CCH61942.1 - 2e-18 67.0 0.0 3.2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cobW PF02492.14 CCH61943.1 - 1.8e-41 141.5 0.1 2.7e-41 140.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCH61943.1 - 0.00034 20.9 2.8 0.00047 20.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCH61943.1 - 0.00049 19.5 0.1 0.0015 18.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCH61943.1 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 CCH61943.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 CCH61943.1 - 0.0053 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 CCH61943.1 - 0.0062 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_17 PF13207.1 CCH61943.1 - 0.0081 16.9 0.8 0.047 14.4 0.1 2.6 1 1 2 3 3 3 1 AAA domain AAA_14 PF13173.1 CCH61943.1 - 0.016 15.0 0.5 0.1 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain T2SE PF00437.15 CCH61943.1 - 0.02 13.7 0.4 0.032 13.1 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 CCH61943.1 - 0.029 14.7 1.9 0.029 14.7 1.3 3.2 2 2 1 3 3 3 0 AAA domain ABC_tran PF00005.22 CCH61943.1 - 0.03 14.6 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 CCH61943.1 - 0.04 12.9 0.2 0.11 11.6 0.1 1.7 1 1 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 CCH61943.1 - 0.055 13.1 0.2 0.055 13.1 0.1 2.2 2 1 1 3 3 3 0 Archaeal ATPase AAA_5 PF07728.9 CCH61943.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCH61943.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ORF6C PF10552.4 CCH61943.1 - 0.13 11.9 1.9 1.7 8.3 0.1 2.9 3 0 0 3 3 3 0 ORF6C domain AAA_19 PF13245.1 CCH61943.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 CCH61943.1 - 0.17 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_transf_22 PF03901.12 CCH61944.1 - 8.9e-24 84.2 16.8 1.2e-23 83.8 11.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Img2 PF05046.9 CCH61945.1 - 3e-26 91.4 0.2 4.3e-26 90.9 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 CCH61945.1 - 0.00025 20.7 0.9 0.0032 17.2 0.6 2.2 1 1 0 1 1 1 1 Translation initiation factor SUI1 WD40 PF00400.27 CCH61946.1 - 7.3e-87 282.4 30.1 1.4e-14 53.2 0.1 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CCH61946.1 - 3.8e-09 35.2 12.6 0.015 13.4 0.1 5.5 2 2 2 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 CCH61946.1 - 5.5e-08 32.7 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CCH61946.1 - 6e-08 32.6 0.4 0.00065 19.4 0.0 3.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 CCH61946.1 - 0.00035 20.0 0.4 0.033 13.5 0.0 2.5 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.6 CCH61946.1 - 0.00054 18.8 2.4 0.35 9.5 0.9 3.5 2 1 0 2 2 2 2 Nup133 N terminal like Nbas_N PF15492.1 CCH61946.1 - 0.0018 17.4 2.0 0.5 9.4 0.1 3.3 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CCH61946.1 - 0.052 11.8 0.1 0.31 9.2 0.1 2.0 1 1 0 1 1 1 0 Cytochrome D1 heme domain ubiquitin PF00240.18 CCH61947.1 - 3.4e-07 29.5 0.1 4.1e-07 29.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCH61947.1 - 0.089 12.4 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 CCH61947.1 - 0.11 13.0 0.0 0.12 12.9 0.0 1.2 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Glucosamine_iso PF01182.15 CCH61948.1 - 5.7e-48 163.2 0.0 9.5e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Macoilin PF09726.4 CCH61948.1 - 0.092 11.0 13.8 0.12 10.6 9.5 1.0 1 0 0 1 1 1 0 Transmembrane protein GAGA_bind PF06217.7 CCH61948.1 - 0.46 10.4 6.5 0.68 9.8 4.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3215 PF11503.3 CCH61949.1 - 4.4e-08 32.6 0.1 9.8e-08 31.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3215) GutM PF06923.6 CCH61949.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.5 1 1 0 1 1 1 0 Glucitol operon activator protein (GutM) PAT1 PF09770.4 CCH61950.1 - 3.5e-239 796.2 62.3 6.4e-239 795.3 43.2 1.4 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.9 CCH61951.1 - 5.8e-88 294.2 3.4 7.3e-88 293.9 2.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DIX PF00778.12 CCH61951.1 - 0.054 13.2 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 DIX domain Ribosom_S12_S23 PF00164.20 CCH61952.1 - 7.5e-45 151.2 1.2 9.2e-45 151.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.16 CCH61953.1 - 8.6e-20 70.1 0.0 9.6e-20 69.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 CCH61954.1 - 2.1e-38 131.4 0.2 4.7e-38 130.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH61954.1 - 9.9e-18 63.7 0.8 3.4e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH61954.1 - 3.2e-06 27.1 0.1 3.2e-06 27.1 0.1 3.8 2 1 2 4 4 4 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CCH61954.1 - 0.004 16.9 0.0 0.29 10.8 0.0 2.7 1 1 0 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.1 CCH61954.1 - 0.59 10.2 3.3 3.1 7.9 2.3 2.3 1 1 0 1 1 1 0 AAA domain NESP55 PF06390.7 CCH61954.1 - 7.7 5.8 11.4 13 5.1 7.9 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Med12 PF09497.5 CCH61955.1 - 6.8e-24 83.6 0.1 1.9e-23 82.2 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Trm112p PF03966.11 CCH61956.1 - 8e-20 70.9 0.1 9.7e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-CCHC_6 PF15288.1 CCH61956.1 - 0.11 12.1 1.8 1.6 8.4 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle TF_Zn_Ribbon PF08271.7 CCH61956.1 - 2 7.8 4.5 1.3 8.4 0.1 2.4 3 0 0 3 3 3 0 TFIIB zinc-binding WD40 PF00400.27 CCH61957.1 - 5e-60 197.3 11.6 2.2e-10 39.9 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCH61957.1 - 7e-25 87.0 14.9 7e-25 87.0 10.3 2.7 2 0 0 2 2 2 1 Tup N-terminal GHMP_kinases_N PF00288.21 CCH61958.1 - 1.9e-08 34.2 3.0 2.9e-08 33.6 1.4 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain Thioredoxin PF00085.15 CCH61959.1 - 8.9e-27 92.8 0.3 1.4e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCH61959.1 - 9e-08 32.1 1.1 4.2e-06 26.7 0.0 2.7 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCH61959.1 - 3.5e-06 27.1 0.5 1.8e-05 24.9 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CCH61959.1 - 2.3e-05 23.9 0.1 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CCH61959.1 - 3.7e-05 23.4 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.1 CCH61959.1 - 0.0049 16.6 0.3 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 CCH61959.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 CCH61959.1 - 0.0084 15.6 0.2 0.022 14.3 0.2 1.7 1 1 0 1 1 1 1 Redoxin TrbC_Ftype PF09673.5 CCH61959.1 - 0.0094 15.5 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin assembly protein Thioredoxin_4 PF13462.1 CCH61959.1 - 0.015 15.2 1.1 1 9.3 0.1 2.3 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 CCH61959.1 - 0.017 14.6 0.1 0.028 13.9 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein KaiB PF07689.7 CCH61959.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiB domain DSBA PF01323.15 CCH61959.1 - 0.034 13.6 0.3 2.2 7.7 0.0 2.3 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 CCH61959.1 - 0.095 12.7 0.1 0.31 11.0 0.0 1.9 1 1 0 1 1 1 0 Glutaredoxin FBD PF08387.5 CCH61960.1 - 0.017 14.5 0.6 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 FBD DUF2153 PF09921.4 CCH61960.1 - 0.033 13.7 0.5 0.066 12.8 0.2 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) PilO PF04350.8 CCH61960.1 - 0.088 12.6 5.6 0.11 12.3 3.9 1.2 1 0 0 1 1 1 0 Pilus assembly protein, PilO ParB PF08775.5 CCH61960.1 - 0.25 11.6 4.9 0.32 11.3 3.0 1.5 1 1 0 1 1 1 0 ParB family ToxN_toxin PF13958.1 CCH61960.1 - 0.6 9.7 7.3 0.81 9.3 5.1 1.3 1 1 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system LRS4 PF10422.4 CCH61960.1 - 3.1 7.0 8.7 4 6.7 6.0 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Flavodoxin_2 PF02525.12 CCH61961.1 - 2.7e-43 147.8 0.1 3e-43 147.6 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCH61961.1 - 3.3e-12 46.1 0.0 7.4e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCH61961.1 - 1.1e-05 24.7 1.1 2.8e-05 23.5 0.8 1.7 1 1 0 1 1 1 1 Flavodoxin DUF362 PF04015.7 CCH61961.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF362) DUF3589 PF12141.3 CCH61962.1 - 1e-58 198.8 12.4 1.1e-39 136.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3589) RhoGAP PF00620.22 CCH61963.1 - 7.7e-34 116.4 1.9 2.7e-32 111.4 0.1 2.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CCH61963.1 - 5.6e-28 96.7 55.6 1.2e-10 41.3 8.5 4.6 4 0 0 4 4 4 4 LIM domain Mut7-C PF01927.11 CCH61963.1 - 0.012 15.5 1.0 0.012 15.5 0.7 3.2 2 0 0 2 2 2 0 Mut7-C RNAse domain G6PD_C PF02781.11 CCH61964.1 - 8.1e-129 428.6 0.0 1e-128 428.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCH61964.1 - 4.4e-60 203.0 0.0 7.8e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Globin PF00042.17 CCH61965.1 - 6.9e-05 23.1 0.0 0.00028 21.1 0.0 2.1 1 1 0 1 1 1 1 Globin CRAL_TRIO PF00650.15 CCH61967.1 - 2.5e-39 134.3 0.0 3.9e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH61967.1 - 3e-12 46.4 0.9 8.2e-12 45.0 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.26 CCH61968.1 - 1.7e-24 85.3 5.6 2.3e-24 84.8 1.6 3.0 3 0 0 3 3 3 1 DnaJ domain zf-C2H2 PF00096.21 CCH61968.1 - 4.1e-07 29.9 4.6 0.00073 19.7 0.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCH61968.1 - 8.6e-07 28.9 1.1 8.6e-07 28.9 0.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCH61968.1 - 3.2e-06 27.1 0.8 1.1e-05 25.4 0.6 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCH61968.1 - 4.8e-05 23.4 1.9 0.012 15.9 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCH61968.1 - 0.00037 20.2 3.5 0.0078 16.0 0.1 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCH61968.1 - 0.0015 18.6 12.0 0.024 14.7 3.5 3.3 3 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CCH61968.1 - 0.0043 16.8 1.3 0.0043 16.8 0.9 3.0 3 1 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) DASH_Dad3 PF08656.5 CCH61968.1 - 5.7 6.7 8.6 5.6 6.7 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad3 SID PF11778.3 CCH61969.1 - 9.3e-33 113.0 8.2 9.3e-33 113.0 5.7 4.0 3 1 0 4 4 4 1 Septation initiation Peptidase_C54 PF03416.14 CCH61970.1 - 1.8e-86 289.7 0.0 2.6e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 CCH61971.1 - 8.3e-85 283.0 0.0 9.4e-85 282.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 CCH61971.1 - 0.047 14.0 0.4 10 6.4 0.0 2.3 1 1 1 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF4030 PF13222.1 CCH61971.1 - 0.087 12.5 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4030) DUF4404 PF14357.1 CCH61971.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) POP1 PF06978.6 CCH61973.1 - 3.5e-64 215.9 13.5 4.4e-64 215.6 6.4 2.7 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CCH61973.1 - 2.2e-31 107.5 1.0 5.2e-31 106.3 0.7 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain Adenylsucc_synt PF00709.16 CCH61974.1 - 6.8e-166 552.1 0.0 7.7e-166 551.9 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.12 CCH61976.1 - 2.1e-85 287.2 39.0 2.7e-85 286.8 27.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Hydrolase_6 PF13344.1 CCH61977.1 - 6.4e-31 106.2 0.0 3.3e-30 103.9 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH61977.1 - 4.1e-14 53.4 0.0 6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH61977.1 - 7.8e-13 47.9 0.0 1.5e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CCH61977.1 - 1.5e-05 25.3 0.0 0.0038 17.4 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 CCH61977.1 - 0.019 14.3 0.4 0.038 13.3 0.0 1.5 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) MgsA_C PF12002.3 CCH61978.1 - 3.1e-51 173.3 0.0 8.6e-51 171.9 0.0 1.8 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CCH61978.1 - 3.7e-15 56.3 0.1 3.7e-15 56.3 0.1 2.0 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCH61978.1 - 3.2e-13 49.2 0.0 6.6e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCH61978.1 - 1.1e-09 38.2 1.9 2e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCH61978.1 - 6.3e-07 29.5 0.1 0.0012 18.8 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCH61978.1 - 2.1e-06 27.4 1.1 8e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CCH61978.1 - 1.3e-05 24.7 0.0 8.2e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 CCH61978.1 - 1.4e-05 25.2 4.6 0.00012 22.2 0.6 3.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCH61978.1 - 6.8e-05 22.1 0.2 0.083 12.0 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCH61978.1 - 7.7e-05 22.1 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CCH61978.1 - 0.0057 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCH61978.1 - 0.0074 16.0 0.0 0.0074 16.0 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase zf-C2HC_2 PF13913.1 CCH61978.1 - 0.02 14.5 0.5 0.042 13.5 0.3 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type RNA_helicase PF00910.17 CCH61978.1 - 0.024 14.7 0.0 0.092 12.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Sgf11 PF08209.6 CCH61978.1 - 0.028 13.7 0.1 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) AAA_18 PF13238.1 CCH61978.1 - 0.037 14.3 7.9 0.047 13.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 CCH61978.1 - 0.056 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CCH61978.1 - 0.057 14.2 1.8 0.17 12.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain Hpt PF01627.18 CCH61979.1 - 2.8e-13 49.6 0.0 4.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Hpt domain DinB PF05163.7 CCH61979.1 - 0.023 14.3 0.1 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 DinB family Strep_67kDa_ant PF06100.6 CCH61979.1 - 0.079 11.2 0.3 0.17 10.2 0.1 1.5 1 1 1 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Metallophos PF00149.23 CCH61980.1 - 7.1e-10 38.6 8.1 2.1e-09 37.0 5.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH61980.1 - 5e-07 29.6 0.0 7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 CCH61980.1 - 0.013 14.6 0.4 0.022 13.9 0.0 1.6 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily LIM_bind PF01803.11 CCH61981.1 - 7.6e-41 139.7 11.4 9.9e-34 116.5 2.2 5.1 5 1 0 6 6 6 2 LIM-domain binding protein VID27 PF08553.5 CCH61982.1 - 1.1e-44 152.9 3.8 1.3e-44 152.7 2.7 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein Ost4 PF10215.4 CCH61983.1 - 6.2e-15 54.3 1.7 6.9e-15 54.2 1.2 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase FUSC_2 PF13515.1 CCH61984.1 - 1.6e-05 24.7 35.2 2e-05 24.4 6.6 2.7 2 1 0 2 2 2 2 Fusaric acid resistance protein-like DUF2421 PF10334.4 CCH61984.1 - 0.00022 20.9 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Rick_17kDa_Anti PF05433.10 CCH61985.1 - 2.2e-07 30.4 8.0 5.3e-07 29.1 5.6 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF533 PF04391.7 CCH61985.1 - 0.05 12.9 2.3 0.074 12.4 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) VIT1 PF01988.14 CCH61985.1 - 0.13 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 VIT family DUF3824 PF12868.2 CCH61985.1 - 0.52 11.2 6.7 0.37 11.7 3.6 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Gly-zipper_Omp PF13488.1 CCH61985.1 - 1.2 8.8 14.8 2.3 7.8 3.4 2.3 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_OmpA PF13436.1 CCH61985.1 - 1.7 8.3 13.6 0.045 13.4 4.5 1.9 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain RIO1 PF01163.17 CCH61986.1 - 1.9e-38 131.7 2.8 1.8e-29 102.4 0.2 2.2 1 1 1 2 2 2 2 RIO1 family Rio2_N PF09202.6 CCH61986.1 - 1.6e-29 101.7 0.1 4.2e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CCH61986.1 - 0.00056 19.7 0.0 0.69 9.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 CCH61986.1 - 0.0095 15.1 1.1 0.015 14.4 0.8 1.3 1 0 0 1 1 1 1 Protein kinase domain NOA36 PF06524.7 CCH61986.1 - 1.1 8.4 11.9 2 7.5 8.3 1.3 1 0 0 1 1 1 0 NOA36 protein YjcQ PF09639.5 CCH61986.1 - 1.6 8.8 6.1 5.1 7.2 0.0 3.7 4 0 0 4 4 4 0 YjcQ protein SDA1 PF05285.7 CCH61986.1 - 2.4 7.3 16.0 23 4.1 0.0 2.2 2 0 0 2 2 2 0 SDA1 Rtt106 PF08512.7 CCH61987.1 - 3.9e-25 87.6 0.7 3.9e-25 87.6 0.5 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3926 PF13080.1 CCH61987.1 - 0.12 11.9 2.0 0.91 9.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3926) CDC45 PF02724.9 CCH61987.1 - 1.1 7.2 13.8 2 6.3 9.5 1.5 1 0 0 1 1 1 0 CDC45-like protein DUF3530 PF12048.3 CCH61987.1 - 1.8 7.5 7.7 0.76 8.7 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) ArfGap PF01412.13 CCH61988.1 - 1.8e-33 114.8 0.5 7.4e-33 112.8 0.0 2.2 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf YjeF_N PF03853.10 CCH61989.1 - 5.5e-36 123.7 0.0 6.6e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Septin PF00735.13 CCH61991.1 - 2.9e-63 213.5 5.0 1.4e-56 191.6 2.1 2.3 2 0 0 2 2 2 2 Septin AAA_18 PF13238.1 CCH61991.1 - 0.00022 21.5 0.1 0.038 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCH61991.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCH61991.1 - 0.0029 17.7 0.0 0.0089 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH61991.1 - 0.019 15.7 0.1 0.11 13.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCH61991.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 CCH61991.1 - 0.037 13.1 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family RNA_helicase PF00910.17 CCH61991.1 - 0.042 14.0 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.18 CCH61991.1 - 0.048 13.4 1.0 0.19 11.5 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 CCH61991.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCH61991.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4611 PF15387.1 CCH61991.1 - 0.21 11.7 5.5 0.64 10.2 3.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 CCH61991.1 - 0.69 9.4 6.8 1.8 8.0 4.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin DAGK_cat PF00781.19 CCH61992.1 - 9.7e-24 83.2 0.0 2.1e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TMA7 PF09072.5 CCH61993.1 - 2.3e-23 82.4 17.9 2.5e-23 82.2 12.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 tRNA-synt_1c PF00749.16 CCH61994.1 - 9.1e-112 372.7 0.0 1.3e-111 372.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CCH61994.1 - 3.2e-55 186.1 0.6 5e-55 185.4 0.4 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CCH61994.1 - 1.9e-33 115.5 0.0 1.1e-31 109.8 0.0 2.5 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CCH61994.1 - 3.2e-24 85.4 5.7 7.1e-24 84.3 4.0 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Red1 PF07964.6 CCH61995.1 - 3.3e-84 283.3 62.5 2.3e-48 164.9 28.2 2.1 1 1 1 2 2 2 2 Rec10 / Red1 Ribosomal_S28e PF01200.13 CCH61996.1 - 7.4e-34 115.3 2.9 8e-34 115.2 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.7 CCH61996.1 - 0.14 11.8 0.1 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region PIN_4 PF13638.1 CCH61997.1 - 4.4e-29 101.2 2.4 4.5e-29 101.2 0.2 2.0 2 0 0 2 2 2 1 PIN domain Zn_clus PF00172.13 CCH61998.1 - 3.8e-08 33.0 11.0 3.8e-08 33.0 7.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP1_TIP1 PF00660.12 CCH61999.1 - 1.4e-29 101.9 0.6 1.4e-29 101.9 0.4 2.0 2 0 0 2 2 2 1 Seripauperin and TIP1 family YTV PF07639.6 CCH61999.1 - 0.042 13.5 1.7 0.082 12.6 1.2 1.5 1 0 0 1 1 1 0 YTV Tcp11 PF05794.8 CCH61999.1 - 0.095 11.3 3.5 0.14 10.8 2.4 1.2 1 0 0 1 1 1 0 T-complex protein 11 Zn_clus PF00172.13 CCH62000.1 - 5.2e-08 32.6 8.4 1.4e-07 31.3 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORF6N PF10543.4 CCH62000.1 - 0.39 10.7 3.3 0.18 11.8 0.2 2.0 2 0 0 2 2 2 0 ORF6N domain Zn_clus PF00172.13 CCH62001.1 - 5.2e-08 32.6 11.6 5.2e-08 32.6 8.1 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3808 PF10300.4 CCH62001.1 - 0.0025 16.4 0.0 0.0041 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Longin PF13774.1 CCH62002.1 - 3.9e-21 74.3 0.6 6.9e-21 73.5 0.4 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCH62002.1 - 3e-17 61.9 0.3 4.6e-17 61.3 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 CCH62002.1 - 0.0014 18.4 0.4 0.0023 17.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CagA PF03507.8 CCH62002.1 - 0.025 14.4 0.1 0.041 13.7 0.1 1.4 1 0 0 1 1 1 0 CagA exotoxin Lipoprotein_9 PF03180.9 CCH62002.1 - 0.035 12.9 0.5 0.12 11.2 0.0 1.8 1 1 0 2 2 2 0 NLPA lipoprotein Phi-29_GP16_7 PF06720.6 CCH62002.1 - 0.088 12.4 0.5 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 DcpS PF05652.7 CCH62003.1 - 9.5e-41 138.6 0.1 1.5e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CCH62003.1 - 3.5e-27 94.9 0.4 1e-26 93.4 0.1 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Med4 PF10018.4 CCH62004.1 - 5.3e-35 120.5 8.8 7.3e-35 120.0 3.1 2.6 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 NAGLU_C PF12972.2 CCH62004.1 - 0.00025 20.5 1.3 0.00042 19.7 0.9 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain V_ATPase_I PF01496.14 CCH62004.1 - 0.21 9.4 4.1 0.28 8.9 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnd1 PF12717.2 CCH62005.1 - 1.4e-49 168.3 30.2 2.4e-47 161.0 0.4 5.7 6 1 0 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CCH62005.1 - 6.6e-18 64.9 4.4 6.6e-18 64.9 3.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 CCH62005.1 - 5.2e-12 44.7 0.0 1.3 9.3 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.1 CCH62005.1 - 8.5e-09 35.5 0.0 0.014 15.6 0.0 4.7 2 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 CCH62005.1 - 0.00059 20.2 0.0 1.2 9.7 0.0 4.8 4 1 1 5 5 5 2 HEAT-like repeat BRCT PF00533.21 CCH62006.1 - 2.5e-12 46.7 0.0 7e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCH62006.1 - 0.00057 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain ATP-synt_F PF01990.12 CCH62007.1 - 6.8e-32 109.7 0.1 8e-32 109.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF257 PF03192.8 CCH62007.1 - 0.057 12.7 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 CmcI PF04989.7 CCH62007.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Cephalosporin hydroxylase Transcrip_reg PF01709.15 CCH62008.1 - 4.2e-69 232.2 5.0 5.1e-69 231.9 3.5 1.1 1 0 0 1 1 1 1 Transcriptional regulator YkyA PF10368.4 CCH62008.1 - 0.62 9.3 5.1 1.1 8.5 3.5 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Mid2 PF04478.7 CCH62009.1 - 2.4e-43 147.2 5.0 2.4e-43 147.2 3.4 5.5 5 1 1 6 6 6 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 CCH62009.1 - 0.33 10.2 1.4 1.9 7.8 0.1 2.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Oxidored_FMN PF00724.15 CCH62010.1 - 4.2e-102 341.6 0.0 4.9e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RabGAP-TBC PF00566.13 CCH62011.1 - 9.8e-06 25.1 6.6 0.0048 16.3 0.1 2.9 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Prp19 PF08606.6 CCH62012.1 - 2.9e-29 100.5 1.6 5.1e-29 99.7 1.1 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CCH62012.1 - 0.0015 18.4 0.1 0.0075 16.2 0.0 2.3 2 0 0 2 2 2 1 U-box domain HALZ PF02183.13 CCH62012.1 - 0.22 11.2 2.5 14 5.5 0.3 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ENTH PF01417.15 CCH62013.1 - 9.1e-30 103.0 2.1 1.7e-29 102.2 1.5 1.4 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 CCH62013.1 - 0.038 13.6 0.6 0.07 12.7 0.4 1.4 1 0 0 1 1 1 0 VHS domain ubiquitin PF00240.18 CCH62014.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 CCH62014.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCH62014.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCH62014.1 - 1e-16 61.0 0.5 0.00056 19.6 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCH62014.1 - 6.8e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCH62014.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCH62014.1 - 5.4e-08 32.7 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CCH62014.1 - 2e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 CCH62014.1 - 0.00019 21.0 0.4 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 CCH62014.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 CCH62014.1 - 0.00083 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Methyltrans_RNA PF04452.9 CCH62014.1 - 0.00085 18.5 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_3_3 PF13750.1 CCH62014.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 CCH62014.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 CCH62014.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 CCH62014.1 - 0.034 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 CCH62014.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 CCH62014.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 CCH62014.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 CCH62014.1 - 0.092 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 CCH62014.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 CCH62014.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 CCH62014.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat DUF1162 PF06650.7 CCH62015.1 - 7.6e-79 264.7 2.1 5.5e-76 255.3 0.2 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCH62015.1 - 6e-40 135.4 0.7 6e-40 135.4 0.5 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter YcxB PF14317.1 CCH62015.1 - 0.0043 16.2 0.3 0.016 14.4 0.2 2.0 1 0 0 1 1 1 1 YcxB-like protein V-SNARE_C PF12352.3 CCH62016.1 - 1.8e-15 56.7 2.7 1.8e-15 56.7 1.9 3.2 4 1 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCH62016.1 - 0.018 14.7 3.9 0.16 11.7 0.0 2.6 2 1 1 3 3 3 0 Sec20 RseA_N PF03872.8 CCH62016.1 - 0.052 13.8 2.4 0.071 13.4 1.1 1.7 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain WXG100 PF06013.7 CCH62016.1 - 0.1 12.5 7.5 1.8 8.6 0.1 3.6 2 1 2 4 4 4 0 Proteins of 100 residues with WXG DUF4065 PF13274.1 CCH62016.1 - 1.6 9.4 4.3 0.71 10.6 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) FUSC PF04632.7 CCH62016.1 - 1.6 7.0 4.2 0.65 8.3 0.8 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 CCH62016.1 - 3.4 5.3 6.3 4.6 4.9 4.4 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 CCH62016.1 - 7.6 6.0 12.4 0.29 10.6 3.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RRM_1 PF00076.17 CCH62017.1 - 1.7e-08 34.0 5.7 0.1 12.2 0.6 4.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH62017.1 - 0.00098 19.0 1.1 0.083 12.8 0.1 3.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH62017.1 - 0.00099 18.9 0.2 0.34 10.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 CCH62018.1 - 1.5e-58 196.9 0.1 8.1e-34 116.8 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCH62018.1 - 1.5e-45 155.8 55.1 2.7e-30 105.7 7.2 4.1 5 0 0 5 5 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CCH62018.1 - 1.2e-08 34.4 4.9 0.0056 15.9 1.2 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCH62018.1 - 2.9e-08 34.3 2.0 1.4e-05 25.5 0.0 4.6 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 CCH62018.1 - 4.8e-08 32.4 0.5 0.0012 18.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH62018.1 - 1.7e-07 31.5 3.8 1e-05 25.6 0.7 6.7 4 3 1 5 5 4 2 AAA domain DUF258 PF03193.11 CCH62018.1 - 1.6e-06 27.3 0.0 0.047 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCH62018.1 - 5e-06 27.3 0.2 0.12 13.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCH62018.1 - 6.2e-06 26.3 0.0 0.31 11.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CCH62018.1 - 6.2e-06 26.6 0.4 0.25 11.8 0.0 3.4 3 0 0 3 3 3 2 Miro-like protein MMR_HSR1 PF01926.18 CCH62018.1 - 8.6e-06 25.7 0.1 0.01 15.7 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 CCH62018.1 - 1.8e-05 23.7 0.8 0.016 14.0 0.0 2.6 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA PF00004.24 CCH62018.1 - 5.6e-05 23.3 0.0 0.54 10.4 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCH62018.1 - 5.7e-05 23.1 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain ATP_bind_1 PF03029.12 CCH62018.1 - 0.00023 20.8 0.0 1.6 8.1 0.0 3.5 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 CCH62018.1 - 0.00029 20.2 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCH62018.1 - 0.00041 20.2 0.2 0.25 11.1 0.0 2.8 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 CCH62018.1 - 0.00042 19.4 0.0 0.5 9.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CCH62018.1 - 0.00052 20.3 0.8 0.96 9.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CCH62018.1 - 0.0013 18.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 CCH62018.1 - 0.0019 17.9 0.7 2 8.0 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CCH62018.1 - 0.0033 16.9 0.4 0.28 10.5 0.0 2.9 3 1 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 CCH62018.1 - 0.0046 16.8 3.4 0.33 10.7 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 cobW PF02492.14 CCH62018.1 - 0.018 14.4 1.2 1.8 7.9 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCH62018.1 - 0.028 14.2 0.0 3.8 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CCH62018.1 - 0.033 13.7 0.2 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCH62018.1 - 0.036 13.6 0.6 8.2 5.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CCH62018.1 - 0.054 12.2 0.1 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 CCH62018.1 - 0.31 10.8 0.7 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AA_permease_2 PF13520.1 CCH62019.1 - 3e-62 210.5 49.3 4.1e-62 210.1 34.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCH62019.1 - 3e-15 55.5 40.9 5.2e-15 54.7 28.4 1.3 1 1 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 CCH62020.1 - 4.2e-10 39.3 12.4 7.6e-10 38.5 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxysterol_BP PF01237.13 CCH62022.1 - 4.8e-92 308.1 0.0 5.9e-92 307.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PAP_central PF04928.12 CCH62023.1 - 4.2e-106 353.4 0.0 9e-106 352.3 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CCH62023.1 - 1.3e-47 161.2 3.6 2.3e-47 160.4 2.5 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CCH62023.1 - 1.3e-11 44.6 0.7 5.1e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain ATP-synt_DE_N PF02823.11 CCH62024.1 - 8.5e-17 60.6 0.0 1.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Trehalase PF01204.13 CCH62025.1 - 7.4e-184 612.1 0.1 1.2e-183 611.3 0.0 1.4 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCH62025.1 - 1.6e-15 56.1 0.5 3.5e-15 55.0 0.3 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain HEAT PF02985.17 CCH62026.1 - 3.1e-20 70.3 2.7 0.0022 17.9 0.0 8.3 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 CCH62026.1 - 1.5e-19 69.8 0.2 5.5e-10 39.4 0.0 7.4 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.1 CCH62026.1 - 2.8e-12 46.7 0.0 1.5e-05 25.1 0.0 6.4 4 3 3 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.2 CCH62026.1 - 2.2e-07 31.1 0.7 0.037 14.4 0.0 5.2 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CCH62026.1 - 2.7e-05 24.0 6.2 0.02 14.7 0.1 3.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 CCH62026.1 - 0.011 15.6 0.1 0.011 15.6 0.1 3.0 4 0 0 4 4 4 0 Importin-beta N-terminal domain DUF840 PF05801.6 CCH62026.1 - 0.11 12.6 1.4 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) S-AdoMet_synt_M PF02772.11 CCH62027.1 - 0.083 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain SAICAR_synt PF01259.13 CCH62028.1 - 9.9e-97 322.9 0.1 1.2e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Pkinase PF00069.20 CCH62029.1 - 8.4e-56 188.9 0.2 2.2e-55 187.6 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62029.1 - 5.1e-33 114.2 0.0 1.9e-31 109.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1395 PF07160.7 CCH62029.1 - 0.0069 15.9 0.4 0.019 14.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1395) Kinase-like PF14531.1 CCH62029.1 - 0.044 12.7 0.0 0.081 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ACCA PF03255.9 CCH62029.1 - 0.079 12.5 1.3 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carn_acyltransf PF00755.15 CCH62030.1 - 4.3e-182 606.3 0.6 5.4e-182 605.9 0.4 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.13 CCH62031.1 - 1.8e-133 444.4 0.6 1.8e-133 444.4 0.4 2.5 2 1 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 CCH62031.1 - 2.6e-11 43.6 0.0 0.00026 21.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCH62031.1 - 4.2e-10 39.5 0.0 0.0036 17.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCH62031.1 - 4.4e-10 39.8 0.0 0.0016 18.8 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCH62031.1 - 4.8e-10 38.7 0.0 0.0011 18.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCH62031.1 - 1.7e-08 33.9 0.0 0.006 16.7 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 CCH62031.1 - 2.6e-06 27.4 0.8 1.2e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CCH62031.1 - 1.2e-05 25.4 0.0 3.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCH62031.1 - 0.00016 21.8 3.3 0.00016 21.8 2.3 5.5 5 1 0 5 5 5 1 Pleckstrin homology domain Phos_pyr_kin PF08543.7 CCH62032.1 - 2.2e-78 262.8 0.0 3.3e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCH62032.1 - 2.7e-58 197.1 0.4 4.4e-58 196.5 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CCH62032.1 - 2.5e-06 26.8 0.0 3.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Tctex-1 PF03645.8 CCH62032.1 - 0.003 17.3 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 Tctex-1 family zf-C2H2_4 PF13894.1 CCH62033.1 - 0.00025 21.1 2.4 0.7 10.3 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH62033.1 - 0.00044 20.4 6.9 0.15 12.4 0.1 3.2 2 1 0 2 2 2 2 Zinc finger, C2H2 type His_Phos_1 PF00300.17 CCH62034.1 - 5.1e-43 146.9 0.0 3.6e-42 144.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AFG1_ATPase PF03969.11 CCH62036.1 - 2.5e-70 237.0 0.1 3.2e-65 220.3 0.0 3.2 2 1 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 CCH62036.1 - 3e-05 24.1 0.0 9e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCH62036.1 - 0.00031 20.5 0.7 0.0014 18.3 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 CCH62036.1 - 0.00059 19.8 0.2 0.032 14.2 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCH62036.1 - 0.0012 19.0 0.0 0.0033 17.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCH62036.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CCH62036.1 - 0.013 15.6 0.0 0.046 13.8 0.0 2.0 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCH62036.1 - 0.04 13.5 0.0 0.096 12.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Bac_DnaA PF00308.13 CCH62036.1 - 0.088 12.4 1.7 0.12 12.0 0.0 2.0 3 0 0 3 3 3 0 Bacterial dnaA protein DUF366 PF04017.7 CCH62036.1 - 0.099 11.9 1.0 0.92 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF366) ATP-synt_D PF01813.12 CCH62037.1 - 2e-65 220.0 6.0 2e-65 220.0 4.1 1.5 2 0 0 2 2 2 1 ATP synthase subunit D Filo_glycop PF01611.11 CCH62037.1 - 0.0079 15.0 0.5 0.0096 14.7 0.3 1.2 1 0 0 1 1 1 1 Filovirus glycoprotein GAS PF13851.1 CCH62037.1 - 0.14 11.3 0.1 0.14 11.3 0.0 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.1 CCH62037.1 - 0.8 9.7 7.2 4.9 7.1 1.5 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Viral_P18 PF04521.8 CCH62037.1 - 1.9 7.9 7.2 4.9 6.6 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Laminin_II PF06009.7 CCH62037.1 - 3 7.6 9.4 0.79 9.4 0.1 3.0 2 2 1 3 3 3 0 Laminin Domain II eIF3g PF12353.3 CCH62038.1 - 4.4e-45 152.6 1.8 7e-45 152.0 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CCH62038.1 - 9.2e-14 50.8 0.1 1.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH62038.1 - 1.9e-09 37.3 0.0 3.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH62038.1 - 2.5e-06 27.2 0.0 5.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3506 PF12014.3 CCH62038.1 - 0.059 13.1 0.2 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) PAP1 PF08601.5 CCH62040.1 - 3.5e-26 92.7 54.9 3.5e-26 92.7 38.1 3.6 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 CCH62040.1 - 8.5e-07 28.8 8.5 8.5e-07 28.8 5.9 2.4 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 CCH62040.1 - 0.0068 16.2 14.0 0.0068 16.2 9.7 2.5 2 1 0 2 2 2 1 Basic region leucine zipper DUF4116 PF13475.1 CCH62040.1 - 0.079 12.4 0.2 0.079 12.4 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Muted PF14942.1 CCH62040.1 - 0.22 11.4 13.0 0.82 9.5 5.5 2.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Aldo_ket_red PF00248.16 CCH62043.1 - 3.2e-61 206.6 0.1 3.6e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Alg6_Alg8 PF03155.10 CCH62044.1 - 2.1e-161 537.9 29.2 2.6e-161 537.6 20.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Arena_RNA_pol PF06317.6 CCH62044.1 - 0.042 10.4 0.1 0.053 10.1 0.1 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase PGM_PMM_I PF02878.11 CCH62045.1 - 2.2e-16 59.5 0.0 1.5e-08 34.2 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCH62045.1 - 1.2e-13 51.2 0.0 1.3e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCH62045.1 - 1.3e-10 41.1 0.1 3.9e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Mitochondr_Som1 PF11093.3 CCH62046.1 - 6.6e-12 45.0 0.5 9.2e-12 44.6 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Lyase_1 PF00206.15 CCH62047.1 - 6.8e-115 383.5 0.0 8.8e-115 383.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCH62047.1 - 1.7e-25 88.8 0.1 1.2e-24 86.1 0.1 2.3 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.7 CCH62047.1 - 0.024 14.3 0.1 0.074 12.8 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain NPR2 PF06218.6 CCH62048.1 - 4e-159 529.8 5.4 4e-159 529.8 3.7 1.8 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 CCH62048.1 - 6.1e-05 21.7 0.3 0.059 11.8 0.0 3.0 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 UPF0122 PF04297.9 CCH62048.1 - 0.024 14.6 0.4 4 7.5 0.0 3.3 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like zf-primase PF09329.6 CCH62049.1 - 7.3e-14 51.1 0.8 1.4e-13 50.2 0.5 1.5 1 0 0 1 1 1 1 Primase zinc finger SynMuv_product PF06047.6 CCH62049.1 - 0.018 14.7 0.6 0.018 14.7 0.4 2.3 3 0 0 3 3 3 0 Ras-induced vulval development antagonist tRNA_anti-codon PF01336.20 CCH62049.1 - 0.035 13.9 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF965 PF06135.7 CCH62049.1 - 0.1 12.6 1.4 0.29 11.2 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF965) Pcc1 PF09341.5 CCH62050.1 - 5e-23 80.9 0.0 5.8e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DNA_ligase_A_M PF01068.16 CCH62051.1 - 7.1e-49 165.9 0.0 1.9e-48 164.5 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCH62051.1 - 7.9e-16 58.3 0.1 1.8e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 CCH62051.1 - 1.8e-08 34.4 3.8 3.6e-06 27.0 0.1 3.5 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 CCH62051.1 - 8.2e-05 22.9 0.0 0.0003 21.1 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region TPR_11 PF13414.1 CCH62052.1 - 3.8e-25 87.3 12.8 5.7e-16 57.9 4.8 3.2 3 1 1 4 4 4 2 TPR repeat TPR_1 PF00515.23 CCH62052.1 - 4e-18 64.1 15.0 2.2e-07 30.1 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62052.1 - 1e-16 59.4 12.5 2.6e-05 23.7 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCH62052.1 - 3.2e-08 33.4 12.7 1.6e-07 31.1 1.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH62052.1 - 4.9e-08 32.5 9.0 0.0012 18.8 0.5 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCH62052.1 - 1.7e-07 31.7 9.9 4.7e-05 23.9 0.9 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH62052.1 - 5.2e-06 25.8 3.3 0.038 13.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62052.1 - 2.9e-05 24.3 1.9 0.92 10.3 0.1 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCH62052.1 - 0.00028 20.6 0.1 0.02 14.7 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62052.1 - 0.00035 20.1 16.0 0.099 12.4 0.8 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCH62052.1 - 0.0016 18.7 7.3 0.21 11.9 0.7 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCH62052.1 - 0.018 14.9 1.2 8.3 6.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCH62052.1 - 0.018 15.1 4.6 0.034 14.2 2.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 CCH62052.1 - 0.024 14.9 0.2 0.69 10.2 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain LemA PF04011.7 CCH62052.1 - 0.032 13.3 0.8 0.059 12.4 0.6 1.4 1 0 0 1 1 1 0 LemA family Fis1_TPR_C PF14853.1 CCH62052.1 - 0.11 12.4 5.1 3 7.7 0.0 3.4 5 0 0 5 5 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CCH62052.1 - 0.11 12.9 8.0 0.89 10.1 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CCH62052.1 - 0.22 10.7 2.4 0.5 9.6 0.0 2.6 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.13 CCH62052.1 - 3.4 7.6 21.5 0.85 9.5 0.2 4.7 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain Anti-adapt_IraP PF10796.4 CCH62052.1 - 3.4 8.0 7.9 4.2 7.8 1.8 2.9 2 1 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Homeobox PF00046.24 CCH62053.1 - 3e-14 52.3 1.4 3e-14 52.3 1.0 2.3 3 0 0 3 3 3 1 Homeobox domain Homeobox_KN PF05920.6 CCH62053.1 - 0.00049 19.7 0.1 0.00049 19.7 0.0 2.7 4 0 0 4 4 4 1 Homeobox KN domain Homez PF11569.3 CCH62053.1 - 0.0096 14.9 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF2120 PF09893.4 CCH62053.1 - 0.028 14.3 1.6 0.049 13.5 1.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Herpes_UL69 PF05459.7 CCH62053.1 - 0.038 13.1 0.6 0.047 12.8 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family DUF3431 PF11913.3 CCH62053.1 - 0.055 12.9 0.5 0.075 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) EIF_2_alpha PF07541.7 CCH62053.1 - 0.068 12.8 0.7 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Mis14 PF08641.7 CCH62053.1 - 0.08 13.0 3.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Nic96 PF04097.9 CCH62053.1 - 0.11 10.5 3.9 0.78 7.7 0.2 2.0 1 1 1 2 2 2 0 Nup93/Nic96 TerB-C PF15615.1 CCH62053.1 - 0.13 12.4 1.1 0.41 10.8 0.8 1.8 1 1 0 1 1 1 0 TerB-C domain Peptidase_S46 PF10459.4 CCH62053.1 - 0.19 10.1 3.7 0.23 9.8 2.5 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF342 PF03961.8 CCH62053.1 - 3.7 5.8 8.3 1.5 7.1 4.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) PIR PF00399.14 CCH62054.1 - 1.1e-39 132.4 66.2 3.1e-08 32.6 5.2 5.6 5 0 0 5 5 5 5 Yeast PIR protein repeat PP2C_2 PF13672.1 CCH62054.1 - 0.0054 16.1 8.8 0.43 9.9 1.7 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C RC-P840_PscD PF10657.4 CCH62054.1 - 0.38 10.5 1.7 37 4.1 0.0 2.9 1 1 2 3 3 3 0 Photosystem P840 reaction centre protein PscD LeuA_dimer PF08502.5 CCH62054.1 - 0.98 9.2 9.8 1.7 8.4 1.2 3.0 1 1 2 3 3 3 0 LeuA allosteric (dimerisation) domain Zn_clus PF00172.13 CCH62055.1 - 4.1e-06 26.6 8.9 8.4e-06 25.6 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 CCH62056.1 - 8.7e-09 35.1 14.6 1.7e-08 34.2 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_3 PF13415.1 CCH62057.1 - 9e-34 114.8 3.7 9.6e-10 38.3 0.0 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain DUF4110 PF13422.1 CCH62057.1 - 1.5e-27 95.2 0.6 1.5e-27 95.2 0.4 4.8 3 2 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 CCH62057.1 - 1.9e-25 88.3 18.2 2.4e-06 27.1 0.0 7.4 5 3 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CCH62057.1 - 1.3e-21 75.7 11.6 2.8e-05 24.0 0.0 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CCH62057.1 - 3.2e-15 55.3 10.1 0.00055 19.4 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 CCH62057.1 - 1.5e-14 53.5 0.0 0.011 15.6 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CCH62057.1 - 7.2e-12 44.5 15.2 0.0011 18.5 0.1 6.2 6 0 0 6 6 6 3 Kelch motif Aldo_ket_red PF00248.16 CCH62058.1 - 2e-64 217.1 0.0 2.3e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 CCH62059.1 - 1.4e-95 320.1 3.4 2.2e-95 319.4 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH62059.1 - 6.8e-10 38.6 14.2 1.3e-09 37.8 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACR_tran PF00873.14 CCH62059.1 - 0.071 10.5 2.4 0.11 9.9 1.7 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family AAA PF00004.24 CCH62060.1 - 0.14 12.3 1.6 0.25 11.5 0.2 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CENP-B_dimeris PF09026.5 CCH62061.1 - 0.072 13.3 12.7 0.19 11.9 8.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain alpha-hel2 PF14456.1 CCH62061.1 - 0.27 9.9 1.0 0.62 8.7 0.7 1.5 1 0 0 1 1 1 0 Alpha-helical domain 2 Ribosomal_L10 PF00466.15 CCH62063.1 - 1.5e-26 92.2 0.1 2.4e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CCH62063.1 - 4e-17 62.3 4.2 6.3e-17 61.7 1.3 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Evr1_Alr PF04777.8 CCH62064.1 - 5e-31 106.4 6.3 6.6e-31 106.0 3.3 1.7 2 0 0 2 2 2 1 Erv1 / Alr family UPF0121 PF03661.8 CCH62065.1 - 0.45 9.6 6.4 0.028 13.5 0.7 1.9 2 1 0 3 3 3 0 Uncharacterised protein family (UPF0121) TMEM190 PF15431.1 CCH62065.1 - 0.45 10.4 2.3 0.36 10.7 0.1 1.9 2 1 1 3 3 3 0 Transmembrane protein 190 Thg1 PF04446.7 CCH62066.1 - 1.4e-46 157.4 0.7 2.1e-46 156.9 0.5 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 CCH62066.1 - 1.9e-36 124.4 0.4 3.1e-36 123.7 0.3 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Xpo1 PF08389.7 CCH62066.1 - 0.016 15.1 0.7 0.079 12.8 0.5 2.0 1 1 0 1 1 1 0 Exportin 1-like protein HABP4_PAI-RBP1 PF04774.10 CCH62067.1 - 1.4e-05 25.5 1.5 1.7e-05 25.2 1.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Mid2 PF04478.7 CCH62070.1 - 9.2e-51 171.3 3.1 9.2e-51 171.3 2.1 4.3 2 1 3 5 5 5 1 Mid2 like cell wall stress sensor Ribosomal_S25 PF03297.10 CCH62072.1 - 2.3e-43 146.5 4.8 2.5e-43 146.3 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 CCH62072.1 - 5e-05 22.9 0.1 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 CCH62072.1 - 0.06 12.6 0.2 0.098 12.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain TAF4 PF05236.9 CCH62072.1 - 0.074 12.3 0.9 0.095 11.9 0.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family HTH_DeoR PF08220.7 CCH62072.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain GntR PF00392.16 CCH62072.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ran_BP1 PF00638.13 CCH62073.1 - 2.5e-34 117.9 0.1 5.9e-34 116.7 0.1 1.7 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 CCH62073.1 - 1.2e-10 41.5 2.6 1.2e-10 41.5 1.8 4.3 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.12 CCH62074.1 - 4.7e-27 93.9 1.1 4.1e-26 90.9 0.2 3.0 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 CCH62074.1 - 5.4e-19 68.4 12.5 2.1e-18 66.4 8.7 2.1 1 0 0 1 1 1 1 MIF4G domain WH2 PF02205.15 CCH62075.1 - 1.4e-08 34.0 0.1 1.5e-07 30.8 0.1 2.6 2 0 0 2 2 2 1 WH2 motif Alba PF01918.16 CCH62076.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Alba Glucan_synthase PF02364.10 CCH62077.1 - 0 1423.2 0.1 0 1422.8 0.1 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCH62077.1 - 2.3e-38 130.6 0.6 6.3e-38 129.2 0.4 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 KOW PF00467.24 CCH62078.1 - 8.3e-05 22.1 1.5 0.00022 20.7 1.0 1.9 1 1 0 1 1 1 1 KOW motif 6PF2K PF01591.13 CCH62079.1 - 3.5e-48 163.5 3.8 3.5e-48 163.5 2.6 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCH62079.1 - 2e-12 47.5 0.0 3.6e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCH62079.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DicB PF05358.6 CCH62079.1 - 0.13 11.7 2.8 5.5 6.5 0.0 3.2 3 0 0 3 3 3 0 DicB protein PAP2 PF01569.16 CCH62080.1 - 2.3e-19 69.3 2.0 4.2e-19 68.4 1.3 1.6 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 CCH62080.1 - 0.079 12.6 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Divergent PAP2 family HEAT_2 PF13646.1 CCH62081.1 - 3.2e-14 52.9 3.0 6.9e-06 26.2 0.0 6.3 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 CCH62081.1 - 5.5e-14 50.9 16.3 4.5e-05 23.1 0.1 10.3 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CCH62081.1 - 1.3e-13 50.9 5.2 8.5e-08 32.4 0.0 7.8 7 2 2 9 9 9 2 HEAT-like repeat Arm PF00514.18 CCH62081.1 - 0.00057 19.6 4.0 0.011 15.5 0.0 4.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CCH62081.1 - 0.053 13.9 3.4 16 5.9 0.0 5.2 3 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 CCH62081.1 - 0.11 12.0 4.6 0.62 9.6 0.1 3.7 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) ACBP PF00887.14 CCH62082.1 - 1.5e-29 101.4 0.9 1.7e-29 101.3 0.6 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 CCH62082.1 - 0.0063 16.6 0.1 0.083 13.0 0.0 2.0 2 0 0 2 2 2 1 FERM central domain GPAT_N PF14829.1 CCH62082.1 - 0.016 14.8 0.1 0.029 14.0 0.0 1.4 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal GatB_Yqey PF02637.13 CCH62082.1 - 0.092 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 GatB domain ORMDL PF04061.9 CCH62083.1 - 1.9e-56 189.4 7.9 2.6e-56 188.9 5.5 1.2 1 0 0 1 1 1 1 ORMDL family Acyl_transf_3 PF01757.17 CCH62083.1 - 7.4 5.3 13.9 5.5 5.7 8.9 1.4 1 1 0 1 1 1 0 Acyltransferase family EF1_GNE PF00736.14 CCH62084.1 - 2.4e-32 110.4 2.1 2.4e-32 110.4 1.4 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CCH62084.1 - 8.9e-12 44.9 4.8 8.9e-12 44.9 3.3 3.0 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CCH62084.1 - 0.013 15.9 0.1 0.042 14.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Fic_N PF13784.1 CCH62084.1 - 0.022 14.6 0.3 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 Fic/DOC family N-terminal GST_C PF00043.20 CCH62084.1 - 0.04 13.8 2.3 0.33 10.9 0.3 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SNF5 PF04855.7 CCH62085.1 - 1.2e-61 208.3 12.7 3.1e-38 131.6 0.1 2.8 2 1 1 3 3 3 2 SNF5 / SMARCB1 / INI1 dCMP_cyt_deam_1 PF00383.17 CCH62086.1 - 4.4e-09 35.9 0.0 7.8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FBA_1 PF07734.8 CCH62086.1 - 0.37 10.4 3.4 0.22 11.2 1.0 1.6 2 0 0 2 2 2 0 F-box associated AIP3 PF03915.8 CCH62087.1 - 1.2e-126 423.0 29.1 1.2e-126 423.0 20.2 2.6 2 1 1 3 3 3 1 Actin interacting protein 3 DNA_pol3_a_NI PF14480.1 CCH62087.1 - 0.00093 18.7 3.9 0.0025 17.4 1.1 2.9 2 0 0 2 2 2 1 DNA polymerase III polC-type N-terminus I HSBP1 PF06825.7 CCH62087.1 - 0.13 11.8 4.0 0.38 10.3 0.4 3.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Tweety PF04906.8 CCH62087.1 - 0.17 10.3 2.9 0.38 9.1 0.0 2.8 3 0 0 3 3 3 0 Tweety tRNA-synt_His PF13393.1 CCH62087.1 - 0.88 8.5 7.7 0.84 8.6 1.1 2.6 2 1 0 2 2 2 0 Histidyl-tRNA synthetase PMC2NT PF08066.7 CCH62087.1 - 6.8 7.0 12.2 0.19 12.0 1.9 3.2 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Mus7 PF09462.5 CCH62088.1 - 2.4e-19 69.6 23.4 7.2e-17 61.4 8.2 3.5 2 1 1 3 3 3 3 Mus7/MMS22 family Myb_DNA-binding PF00249.26 CCH62089.1 - 3.1e-05 23.9 0.1 9.6e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH62089.1 - 4.6 7.4 12.2 0.21 11.6 0.3 3.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain Cullin PF00888.17 CCH62090.1 - 1.4e-86 291.3 45.8 2e-86 290.8 31.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCH62090.1 - 4.7e-24 84.0 2.0 4.7e-24 84.0 1.4 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain Pex24p PF06398.6 CCH62091.1 - 3e-51 174.3 12.0 4.6e-51 173.6 8.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.13 CCH62092.1 - 1.4e-30 104.8 3.0 1.5e-30 104.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta PF02270.10 CCH62093.1 - 2.9e-93 312.6 17.4 4.8e-93 311.9 12.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Prp18 PF02840.10 CCH62094.1 - 1.3e-28 99.6 0.9 2.1e-28 98.9 0.6 1.5 1 1 0 1 1 1 1 Prp18 domain Rpr2 PF04032.11 CCH62094.1 - 0.17 11.7 2.9 0.28 11.0 1.9 1.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain WD40 PF00400.27 CCH62095.1 - 1.7e-31 106.9 8.7 6.2e-07 29.0 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCH62095.1 - 5e-08 32.8 0.4 0.033 13.8 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 CCH62095.1 - 0.002 17.8 0.1 0.75 9.5 0.0 2.6 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Rep_fac-A_C PF08646.5 CCH62096.1 - 7.9e-58 194.3 4.7 4.4e-56 188.6 1.1 2.8 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CCH62096.1 - 1.3e-18 66.6 1.2 3.8e-11 42.6 0.0 4.5 4 1 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 CCH62096.1 - 8.9e-05 22.2 0.1 0.0007 19.3 0.0 2.5 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 CCH62096.1 - 0.022 14.8 3.9 0.031 14.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 BRCA-2_OB1 PF09103.5 CCH62096.1 - 0.057 13.1 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Flocculin PF00624.13 CCH62097.1 - 5.8e-19 67.6 104.2 8.8e-13 47.8 10.1 35.7 34 2 1 35 35 35 7 Flocculin repeat Med3 PF11593.3 CCH62097.1 - 9.5e-06 25.0 0.0 9.5e-06 25.0 0.0 14.2 6 6 6 14 14 14 1 Mediator complex subunit 3 fungal Ank_2 PF12796.2 CCH62099.1 - 3.5e-14 52.8 0.1 2.5e-13 50.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCH62099.1 - 5.9e-13 47.9 0.1 2.3e-08 33.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCH62099.1 - 9.6e-12 44.7 0.1 4.1e-08 33.2 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH62099.1 - 2.5e-09 36.4 0.1 9.8e-05 22.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCH62099.1 - 2.3e-08 34.3 0.1 8.5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF2435 PF10363.4 CCH62100.1 - 2.1e-26 91.6 0.9 2.1e-26 91.6 0.6 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CCH62100.1 - 0.01 15.3 1.0 0.024 14.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) DegT_DnrJ_EryC1 PF01041.12 CCH62100.1 - 0.087 11.8 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family HSP90 PF00183.13 CCH62101.1 - 5.9e-254 843.3 38.8 6.9e-254 843.1 26.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CCH62101.1 - 1.7e-11 43.8 0.0 3.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCH62101.1 - 2.3e-10 40.2 0.1 2.3e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tom37_C PF11801.3 CCH62101.1 - 3.1 7.6 12.2 3.3 7.5 4.9 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain DDHD PF02862.12 CCH62101.1 - 6.2 6.5 10.2 1.8 8.3 3.5 2.2 2 0 0 2 2 2 0 DDHD domain TBCC PF07986.7 CCH62102.1 - 1.2e-09 37.5 3.5 3.1e-09 36.2 2.4 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor C UAA PF08449.6 CCH62103.1 - 3.8e-79 265.7 18.4 4.4e-79 265.5 12.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCH62103.1 - 3.4e-07 30.0 18.0 5.6e-07 29.3 5.0 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CCH62103.1 - 5.1e-07 29.7 25.3 6.1e-07 29.5 6.7 3.6 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CCH62103.1 - 1.6e-05 25.0 22.1 0.0025 17.9 6.4 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 CCH62103.1 - 0.00026 20.1 8.3 0.01 14.9 1.7 2.6 1 1 1 2 2 2 2 Nucleotide-sugar transporter DUF1614 PF07758.6 CCH62103.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1614) Rhomboid PF01694.17 CCH62104.1 - 1.9e-18 66.9 13.2 1.9e-18 66.9 9.1 1.6 2 0 0 2 2 2 1 Rhomboid family Ribosomal_S17 PF00366.15 CCH62105.1 - 6.1e-15 55.0 0.4 1e-14 54.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 YlbD_coat PF14071.1 CCH62105.1 - 0.55 10.3 8.8 0.04 13.9 2.6 1.9 2 1 0 2 2 2 0 Putative coat protein GDC-P PF02347.11 CCH62106.1 - 2.8e-186 619.3 0.1 5.1e-174 578.9 0.0 2.8 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CCH62106.1 - 0.00031 19.9 0.0 0.003 16.7 0.0 2.3 2 1 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CCH62106.1 - 0.0029 15.9 0.0 0.0066 14.7 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CCH62107.1 - 1.1e-38 133.2 0.0 1.6e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCH62107.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase SPX PF03105.14 CCH62109.1 - 4.4e-42 144.7 6.6 4.4e-42 144.7 4.6 2.2 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 CCH62109.1 - 1.8e-25 89.7 39.5 2.6e-25 89.2 27.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCH62109.1 - 2e-15 56.2 35.6 3.4e-14 52.1 8.8 2.2 1 1 1 2 2 2 2 Citrate transporter DUF373 PF04123.8 CCH62109.1 - 2.4 7.0 23.0 0.012 14.6 4.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF373) PFK PF00365.15 CCH62110.1 - 4e-167 554.2 1.5 3.3e-124 413.4 1.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 CCH62110.1 - 0.059 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase-like domain Porin_3 PF01459.17 CCH62111.1 - 2.1e-83 279.8 0.2 2.4e-83 279.5 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Med9 PF07544.8 CCH62112.1 - 1.5e-19 69.5 1.2 3.3e-19 68.3 0.8 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF3243 PF11588.3 CCH62112.1 - 0.021 14.7 0.4 0.047 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Cortex-I_coil PF09304.5 CCH62112.1 - 0.025 14.6 5.7 0.039 13.9 3.9 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Sipho_Gp157 PF05565.6 CCH62112.1 - 0.03 13.9 6.3 0.033 13.7 3.3 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 DUF4047 PF13256.1 CCH62112.1 - 0.29 11.1 4.6 0.46 10.4 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4200 PF13863.1 CCH62112.1 - 0.84 9.5 6.6 1 9.3 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IFT43 PF15305.1 CCH62112.1 - 1.1 9.2 8.5 0.23 11.4 0.9 2.7 2 1 1 3 3 3 0 Intraflagellar transport protein 43 Whi5 PF08528.6 CCH62113.1 - 1.5e-06 27.6 0.1 2.9e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Whi5 like TcdB_N PF12918.2 CCH62113.1 - 0.75 9.9 4.9 0.31 11.1 1.1 2.1 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain XPA_C PF05181.7 CCH62114.1 - 3.8e-26 90.4 0.5 8.7e-26 89.2 0.3 1.7 1 0 0 1 1 1 1 XPA protein C-terminus SUKH_6 PF14568.1 CCH62114.1 - 0.013 15.9 1.0 0.043 14.2 0.3 2.1 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall Cyclin_N PF00134.18 CCH62115.1 - 7.3e-31 106.3 0.0 1.6e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain SAGA-Tad1 PF12767.2 CCH62116.1 - 1.2e-60 205.3 5.9 1.3e-59 201.8 4.1 2.5 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Pex14_N PF04695.8 CCH62116.1 - 1.1 9.3 5.8 0.48 10.4 1.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ycf54 PF10674.4 CCH62117.1 - 0.15 12.2 15.2 0.53 10.4 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2488) Reo_sigmaC PF04582.7 CCH62117.1 - 1.1 8.3 12.8 1 8.4 2.4 2.8 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Fer2 PF00111.22 CCH62118.1 - 9.4e-14 50.9 0.5 1.3e-13 50.5 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.3 CCH62119.1 - 4.5e-22 77.8 8.7 1.2e-21 76.5 3.3 2.6 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CCH62119.1 - 2.2e-14 53.3 3.4 2.2e-14 53.3 2.4 2.6 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 CCH62119.1 - 0.00013 21.6 1.3 0.00013 21.6 0.9 2.4 2 1 0 2 2 2 1 Sec20 Catalase-rel PF06628.7 CCH62119.1 - 0.095 12.5 1.1 0.96 9.3 0.1 2.6 3 0 0 3 3 3 0 Catalase-related immune-responsive Methyltransf_9 PF08003.6 CCH62119.1 - 0.41 9.3 5.4 0.068 11.8 1.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Prominin PF05478.6 CCH62119.1 - 0.6 7.5 10.4 2.1 5.8 7.2 1.7 1 1 0 1 1 1 0 Prominin Flu_NS2 PF00601.14 CCH62119.1 - 0.75 10.0 5.9 0.3 11.3 0.3 2.6 2 2 0 2 2 2 0 Influenza non-structural protein (NS2) Glyco_hydro_63 PF03200.11 CCH62120.1 - 2.1e-06 25.8 10.3 4.7e-05 21.4 0.2 4.3 4 1 0 4 4 4 3 Mannosyl oligosaccharide glucosidase RabGAP-TBC PF00566.13 CCH62122.1 - 3.8e-52 176.8 0.4 3.8e-52 176.8 0.3 3.1 2 1 1 3 3 3 1 Rab-GTPase-TBC domain CCDC155 PF14662.1 CCH62122.1 - 0.0062 16.1 23.2 0.011 15.3 9.5 2.4 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 HOOK PF05622.7 CCH62122.1 - 0.012 13.5 20.0 0.018 12.8 13.8 1.2 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.10 CCH62122.1 - 2.5 7.6 27.9 0.55 9.7 4.5 3.7 1 1 2 3 3 3 0 Septum formation initiator ATG16 PF08614.6 CCH62122.1 - 8.8 6.0 31.1 0.091 12.5 4.6 3.7 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Fungal_trans PF04082.13 CCH62123.1 - 1.9e-23 82.6 17.8 1.9e-23 82.6 12.4 3.3 3 1 0 3 3 3 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 CCH62123.1 - 2.6e-12 46.4 3.7 1.2e-11 44.3 0.8 2.7 2 0 0 2 2 2 1 Gal4-like dimerisation domain Zn_clus PF00172.13 CCH62123.1 - 7.4e-07 28.9 18.4 1.6e-06 27.8 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACC_central PF08326.7 CCH62124.1 - 1.8e-263 875.8 0.0 1.8e-263 875.8 0.0 1.5 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CCH62124.1 - 1.6e-177 590.8 0.0 2.1e-177 590.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CCH62124.1 - 5.4e-52 176.1 0.0 1.4e-51 174.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCH62124.1 - 1.8e-25 89.1 0.0 4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCH62124.1 - 7.5e-21 74.1 0.0 4.4e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CCH62124.1 - 2e-17 62.5 0.1 6e-17 61.0 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCH62124.1 - 2.3e-09 36.4 0.0 0.0035 16.1 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCH62124.1 - 2.1e-08 34.1 0.0 8.4e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCH62124.1 - 0.00035 20.0 0.0 0.00091 18.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCH62124.1 - 0.0088 15.9 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCH62124.1 - 0.018 14.7 0.0 7.1 6.3 0.0 2.7 1 1 1 2 2 2 0 Biotin-lipoyl like ATP-grasp PF02222.17 CCH62124.1 - 0.056 12.7 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain F_bP_aldolase PF01116.15 CCH62125.1 - 5.7e-94 314.4 0.1 6.4e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 CCH62125.1 - 0.021 14.7 0.1 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin SNAP PF14938.1 CCH62125.1 - 0.062 12.4 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP DUF89 PF01937.14 CCH62126.1 - 3e-109 365.0 2.9 3.4e-109 364.9 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 TAP42 PF04177.7 CCH62127.1 - 8.5e-89 297.8 31.7 9.8e-89 297.6 22.0 1.0 1 0 0 1 1 1 1 TAP42-like family adh_short PF00106.20 CCH62128.1 - 2.1e-07 31.0 0.0 0.0044 16.9 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCH62128.1 - 0.012 15.2 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 KR domain Frag1 PF10277.4 CCH62129.1 - 6.7e-68 228.3 10.1 9.4e-68 227.8 7.0 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2207 PF09972.4 CCH62129.1 - 3.3 6.1 8.6 3.2 6.2 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) DUF3812 PF12757.2 CCH62130.1 - 3.3e-24 85.2 1.1 3.3e-24 85.2 0.8 4.7 5 1 1 7 7 7 1 Protein of unknown function (DUF3812) FCH PF00611.18 CCH62131.1 - 8.8e-15 54.6 1.4 8.8e-15 54.6 0.9 3.4 5 0 0 5 5 5 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CCH62131.1 - 0.0027 17.0 0.0 0.0062 15.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Histone PF00125.19 CCH62132.1 - 5e-24 84.2 0.3 8.1e-24 83.5 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCH62132.1 - 0.022 14.9 0.1 0.039 14.1 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S DASH_Dad4 PF08650.5 CCH62132.1 - 0.15 11.9 2.2 0.4 10.6 1.5 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pkinase PF00069.20 CCH62133.1 - 1.5e-37 129.2 0.0 1.4e-36 125.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62133.1 - 4.7e-22 78.3 0.3 9.6e-16 57.6 0.1 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH62133.1 - 5.6e-05 22.2 0.0 0.00036 19.5 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCH62133.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 CCH62134.1 - 1.1e-11 44.3 12.5 2e-05 24.6 1.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62134.1 - 3.4e-10 39.5 12.2 7.7e-05 22.7 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62134.1 - 9.3e-10 38.3 16.8 1.6e-07 31.2 2.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCH62134.1 - 6.8e-06 26.0 7.5 0.00031 20.7 1.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCH62134.1 - 1.9e-05 24.4 7.5 0.001 18.8 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCH62134.1 - 0.0041 17.2 4.9 0.046 13.9 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-BED PF02892.10 CCH62134.1 - 0.0043 16.7 5.7 0.4 10.4 0.6 2.7 2 0 0 2 2 2 2 BED zinc finger zf-Di19 PF05605.7 CCH62134.1 - 0.017 15.1 4.4 0.054 13.6 3.0 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 CCH62134.1 - 2.6 6.4 5.2 3.4 6.0 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 CCH62134.1 - 4.3 7.5 14.1 1.8 8.6 0.2 3.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.6 CCH62134.1 - 9.6 5.8 9.6 3.4 7.3 0.1 2.8 2 1 1 3 3 3 0 GAGA factor CorA PF01544.13 CCH62135.1 - 3.9e-38 131.1 10.2 1.9e-21 76.3 0.2 3.8 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein PC4 PF02229.11 CCH62136.1 - 2.3e-21 74.7 0.0 4.4e-21 73.8 0.0 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Bap31 PF05529.7 CCH62137.1 - 3.9e-36 124.3 0.1 5.8e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Ndc1_Nup PF09531.5 CCH62137.1 - 1.1 7.5 4.5 0.29 9.5 0.6 1.7 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SRF-TF PF00319.13 CCH62138.1 - 5.1e-25 86.4 0.3 8.1e-25 85.8 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Podoplanin PF05808.6 CCH62138.1 - 0.7 9.4 4.8 0.4 10.2 1.5 2.0 2 0 0 2 2 2 0 Podoplanin GST_N_2 PF13409.1 CCH62139.1 - 3.9e-15 55.6 0.0 1.1e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCH62139.1 - 0.00023 20.9 0.0 0.00068 19.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCH62139.1 - 0.0014 18.8 0.0 0.12 12.5 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCH62140.1 - 6.1e-10 38.9 0.0 9.4e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCH62140.1 - 1.5e-06 28.5 0.0 2.7e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCH62140.1 - 1e-05 25.3 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PX PF00787.19 CCH62140.1 - 0.03 14.0 0.6 0.088 12.6 0.2 1.8 2 1 0 2 2 2 0 PX domain Sod_Fe_C PF02777.13 CCH62141.1 - 1.7e-08 34.2 0.9 2.9e-05 23.8 0.1 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Cu PF00080.15 CCH62142.1 - 1.8e-43 148.0 2.9 2.1e-43 147.8 2.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Kei1 PF08552.6 CCH62143.1 - 7.4e-44 149.6 18.2 1.1e-42 145.8 12.6 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 YwiC PF14256.1 CCH62143.1 - 0.15 12.1 3.0 0.43 10.6 1.2 2.2 1 1 1 2 2 2 0 YwiC-like protein DUF4064 PF13273.1 CCH62143.1 - 1.6 8.8 11.7 3.3 7.8 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) DUF2085 PF09858.4 CCH62143.1 - 4.9 7.3 6.4 2 8.5 0.0 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) UBN2 PF14223.1 CCH62144.1 - 0.038 13.7 0.3 0.097 12.4 0.1 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type zf-C4pol PF14260.1 CCH62144.1 - 0.057 13.4 0.5 0.13 12.2 0.4 1.5 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta OB_NTP_bind PF07717.11 CCH62145.1 - 1.2e-16 60.5 0.0 4.2e-16 58.7 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCH62145.1 - 1.7e-12 47.0 0.1 5.6e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 CCH62145.1 - 2.9e-12 46.4 3.1 2.9e-12 46.4 2.1 2.5 2 0 0 2 2 2 1 RWD domain HA2 PF04408.18 CCH62145.1 - 2.3e-10 40.4 0.0 2.3e-10 40.4 0.0 2.9 3 0 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CCH62145.1 - 8.6e-10 38.3 2.5 3.2e-09 36.5 0.9 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH62145.1 - 1.2e-05 25.4 1.1 0.00015 21.9 0.1 2.8 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCH62145.1 - 0.00043 19.4 1.0 0.0014 17.8 0.2 2.3 2 1 0 2 2 2 1 KaiC T2SE PF00437.15 CCH62145.1 - 0.00061 18.7 0.1 0.0016 17.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CCH62145.1 - 0.001 18.5 0.1 0.0025 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 CCH62145.1 - 0.0018 17.9 0.0 0.0076 15.9 0.0 2.1 1 0 0 1 1 1 1 NACHT domain Zot PF05707.7 CCH62145.1 - 0.0033 16.9 0.5 0.022 14.2 0.0 2.4 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 CCH62145.1 - 0.0035 17.3 0.0 0.053 13.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCH62145.1 - 0.0059 16.0 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH62145.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 CCH62145.1 - 0.061 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family UBA PF00627.26 CCH62145.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain EAP30 PF04157.11 CCH62146.1 - 1.1e-39 135.8 0.6 1.8e-39 135.2 0.4 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CCH62146.1 - 2.8e-33 113.5 0.1 7.4e-33 112.2 0.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 CCH62146.1 - 0.0017 17.3 8.6 0.002 17.1 0.5 2.9 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others DZR PF12773.2 CCH62146.1 - 0.0028 17.4 6.2 0.01 15.6 1.0 2.4 2 0 0 2 2 2 1 Double zinc ribbon bPH_3 PF14470.1 CCH62146.1 - 0.0033 17.6 0.1 0.011 15.9 0.1 1.9 1 0 0 1 1 1 1 Bacterial PH domain Cas_CXXC_CXXC PF09706.5 CCH62146.1 - 0.016 15.3 8.1 0.21 11.8 0.3 3.8 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-ribbon_3 PF13248.1 CCH62146.1 - 0.019 14.1 0.5 0.019 14.1 0.4 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 CCH62146.1 - 0.03 13.8 11.5 0.13 11.8 0.1 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger GRAM PF02893.15 CCH62146.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 GRAM domain MinC_N PF05209.8 CCH62146.1 - 0.088 12.5 0.6 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain Rubredoxin PF00301.15 CCH62146.1 - 8.9 6.2 7.3 4.6 7.1 0.0 3.4 4 0 0 4 4 4 0 Rubredoxin ABC_membrane_2 PF06472.10 CCH62147.1 - 5.4e-67 225.8 13.1 1.7e-42 145.4 1.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCH62147.1 - 6.2e-16 58.9 1.1 1.1e-14 54.8 0.0 3.2 2 1 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CCH62147.1 - 0.012 15.7 0.0 0.061 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCH62147.1 - 0.025 14.0 0.0 0.073 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lysis_S PF04971.7 CCH62147.1 - 0.049 13.3 0.8 1.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Lysis protein S AAA_16 PF13191.1 CCH62147.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SUR7 PF06687.7 CCH62148.1 - 1.5e-30 106.4 12.8 1.8e-30 106.0 8.9 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCH62148.1 - 0.0011 18.6 4.3 0.0011 18.6 3.0 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2663 PF10864.3 CCH62148.1 - 0.013 15.7 2.1 0.03 14.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) 2TM PF13239.1 CCH62148.1 - 0.15 12.1 2.8 0.14 12.2 0.3 2.1 1 1 1 2 2 2 0 2TM domain DUF4064 PF13273.1 CCH62148.1 - 3.4 7.8 10.5 1.7 8.8 0.7 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF21 PF01595.15 CCH62148.1 - 5.6 6.2 9.0 6.4 6.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF21 adh_short PF00106.20 CCH62149.1 - 4.9e-12 46.0 0.0 8.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AAA_14 PF13173.1 CCH62149.1 - 0.013 15.4 0.3 0.092 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain 3Beta_HSD PF01073.14 CCH62149.1 - 0.027 13.2 0.0 0.048 12.3 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 CCH62149.1 - 0.032 13.8 0.1 1.4 8.5 0.0 2.6 2 1 0 2 2 2 0 KR domain Epimerase PF01370.16 CCH62149.1 - 0.15 11.5 0.1 0.27 10.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SPC25 PF06703.6 CCH62150.1 - 1.5e-37 128.7 0.8 1.7e-37 128.5 0.5 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DDE_Tnp_1_3 PF13612.1 CCH62150.1 - 0.0021 17.7 0.3 0.0033 17.2 0.2 1.3 1 0 0 1 1 1 1 Transposase DDE domain MpPF26 PF07666.6 CCH62150.1 - 0.055 13.3 0.8 0.055 13.3 0.6 1.6 2 0 0 2 2 2 0 M penetrans paralogue family 26 PspB PF06667.7 CCH62150.1 - 0.056 13.3 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF1900 PF08954.6 CCH62151.1 - 9.5e-47 157.9 0.0 2.1e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCH62151.1 - 1.2e-31 108.1 0.5 2.5e-31 107.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCH62151.1 - 1.8e-26 91.0 3.5 1.4e-07 31.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 CCH62151.1 - 3.3e-06 25.5 0.1 0.0015 16.7 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CCH62151.1 - 0.0044 16.7 0.2 0.18 11.4 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A SlyX PF04102.7 CCH62151.1 - 0.015 15.6 1.5 0.04 14.2 1.0 1.8 1 0 0 1 1 1 0 SlyX RBD-FIP PF09457.5 CCH62151.1 - 0.038 13.7 3.6 0.091 12.5 2.5 1.6 1 0 0 1 1 1 0 FIP domain SEN1_N PF12726.2 CCH62152.1 - 1.5e-204 681.1 30.9 2.2e-204 680.6 21.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CCH62152.1 - 3.2e-70 236.3 0.3 3.2e-70 236.3 0.2 3.5 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 CCH62152.1 - 2.1e-61 206.8 0.0 5.7e-61 205.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH62152.1 - 1.1e-10 41.1 0.0 3.3e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCH62152.1 - 2.7e-07 30.3 0.0 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2935 PF11155.3 CCH62153.1 - 0.11 12.5 9.5 0.59 10.2 1.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Metallophos PF00149.23 CCH62154.1 - 3.9e-37 127.5 4.9 3.9e-37 127.5 3.4 2.8 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase WGG PF10273.4 CCH62155.1 - 1.3e-29 102.0 1.0 2.9e-29 100.9 0.7 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RNR_inhib PF08591.5 CCH62156.1 - 0.0036 18.1 8.1 0.0051 17.6 2.9 2.4 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor InvH PF04741.7 CCH62156.1 - 2.3 8.0 7.5 1.3 8.8 1.1 2.2 1 1 0 2 2 2 0 InvH outer membrane lipoprotein Aminotran_3 PF00202.16 CCH62157.1 - 1.7e-98 329.6 0.0 2e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 CCH62157.1 - 0.024 13.5 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Sec39 PF08314.6 CCH62158.1 - 1.7e-62 211.3 30.1 2.5e-62 210.8 20.9 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 BAH PF01426.13 CCH62159.1 - 7.6e-13 48.2 2.5 1.1e-12 47.7 0.5 2.3 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.1 CCH62159.1 - 0.68 9.8 0.0 0.68 9.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain SUR7 PF06687.7 CCH62160.1 - 9.8e-08 31.8 10.5 2.1e-07 30.7 7.3 1.6 1 1 0 1 1 1 1 SUR7/PalI family DUF3901 PF13040.1 CCH62161.1 - 0.028 13.6 5.1 0.094 12.0 3.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) Acetyltransf_1 PF00583.19 CCH62162.1 - 4.3e-07 29.8 0.0 2.8e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family MATH PF00917.21 CCH62162.1 - 0.0021 18.2 6.2 0.54 10.5 0.1 2.8 2 1 0 2 2 2 2 MATH domain Acetyltransf_7 PF13508.1 CCH62162.1 - 0.0075 16.4 0.1 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TFIID-18kDa PF02269.11 CCH62162.1 - 0.035 13.9 0.5 2.5 7.9 0.0 2.7 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Acetyltransf_CG PF14542.1 CCH62162.1 - 0.051 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase zf-C2H2_4 PF13894.1 CCH62163.1 - 5.1e-07 29.5 13.5 1.3e-05 25.1 2.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH62163.1 - 8.3e-06 25.8 4.7 8.3e-06 25.8 3.3 3.0 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 CCH62163.1 - 1.1e-05 25.4 3.3 1.8e-05 24.7 2.3 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CCH62163.1 - 6.5e-05 23.0 13.6 0.14 12.5 0.2 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_2 PF12756.2 CCH62163.1 - 0.0053 16.8 8.2 0.23 11.5 0.9 2.5 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) Terminase_GpA PF05876.7 CCH62163.1 - 0.16 10.3 3.1 0.21 9.8 2.2 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-H2C2_5 PF13909.1 CCH62163.1 - 0.59 10.4 10.9 0.31 11.3 1.0 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CCH62163.1 - 1 9.6 6.6 0.32 11.2 1.9 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-UDP PF14569.1 CCH62163.1 - 1.3 8.8 6.6 3.6 7.3 0.6 2.7 2 1 1 3 3 3 0 Zinc-binding RING-finger zf-C2H2_6 PF13912.1 CCH62163.1 - 2.2 8.2 5.5 1.4 8.8 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Cg6151-P PF10233.4 CCH62164.1 - 2.8e-39 133.5 14.9 3.6e-39 133.2 10.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF308 PF03729.8 CCH62164.1 - 9 6.3 18.7 0.78 9.7 0.9 3.4 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) E1-E2_ATPase PF00122.15 CCH62165.1 - 0.42 9.6 0.0 0.42 9.6 0.0 1.6 2 0 0 2 2 2 0 E1-E2 ATPase HMG_box PF00505.14 CCH62166.1 - 5e-33 113.1 9.6 1.3e-17 63.7 1.4 2.6 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCH62166.1 - 3.8e-18 65.6 6.3 1.4e-10 41.3 1.4 2.6 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.7 CCH62166.1 - 8.9e-07 28.4 0.0 0.0065 16.1 0.0 2.9 2 0 0 2 2 2 2 CHDNT (NUC034) domain Tol_Tol_Ttg2 PF05494.7 CCH62166.1 - 0.0065 16.0 4.6 0.57 9.7 0.0 3.2 3 0 0 3 3 3 2 Toluene tolerance, Ttg2 dsDNA_bind PF01984.15 CCH62167.1 - 2.7e-24 85.2 0.8 3.7e-24 84.7 0.6 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Maelstrom PF13017.1 CCH62167.1 - 0.038 13.4 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 piRNA pathway germ-plasm component EF-1_beta_acid PF10587.4 CCH62167.1 - 0.062 13.4 0.7 0.062 13.4 0.5 3.1 4 0 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region PHD PF00628.24 CCH62168.1 - 1.7e-15 56.4 18.6 1.6e-11 43.6 5.7 3.0 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 CCH62168.1 - 0.0031 17.6 5.7 0.0048 17.0 0.7 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain TFIIS_C PF01096.13 CCH62168.1 - 0.21 11.2 0.1 0.21 11.2 0.1 3.7 4 1 1 5 5 5 0 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 CCH62168.1 - 0.57 9.9 12.1 0.27 11.0 0.2 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Form_Nir_trans PF01226.12 CCH62170.1 - 2.3e-61 206.8 21.4 2.9e-61 206.5 14.8 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BRAP2 PF07576.7 CCH62171.1 - 8.7e-22 76.7 4.5 1.4e-20 72.8 1.4 2.8 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CCH62171.1 - 1.8e-20 72.7 7.6 1.8e-20 72.7 5.3 2.0 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CCH62171.1 - 1.2e-09 37.8 10.4 1.2e-09 37.8 7.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CCH62171.1 - 2.3e-05 24.0 10.0 2.3e-05 24.0 6.9 2.5 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCH62171.1 - 2.3e-05 23.9 7.4 2.3e-05 23.9 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH62171.1 - 2.8e-05 24.0 11.8 2.8e-05 24.0 8.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH62171.1 - 0.00011 21.8 12.0 0.00031 20.3 8.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCH62171.1 - 0.00041 20.4 6.0 0.00041 20.4 4.1 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCH62171.1 - 0.0013 18.4 7.5 0.0066 16.1 5.2 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CCH62171.1 - 0.012 15.4 4.2 0.032 14.0 2.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CCH62171.1 - 0.056 13.0 7.7 0.13 11.8 5.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FliJ PF02050.11 CCH62171.1 - 0.17 11.9 17.5 0.36 10.8 1.4 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein zf-C3HC4_4 PF15227.1 CCH62171.1 - 0.3 10.9 8.1 1.6 8.7 5.7 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF869 PF05911.6 CCH62171.1 - 0.66 8.1 32.9 0.84 7.7 22.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Pribosyltran_N PF13793.1 CCH62172.1 - 2.3e-33 114.3 0.1 2.6e-31 107.7 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCH62172.1 - 6.9e-27 94.3 9.1 7.9e-24 84.4 3.5 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCH62172.1 - 4.1e-05 23.2 0.7 0.00011 21.8 0.5 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain HAD_2 PF13419.1 CCH62173.1 - 3.7e-13 50.0 0.0 4.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH62173.1 - 1.8e-08 35.0 0.0 1.7e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CCH62173.1 - 1.1e-05 25.1 0.0 0.0031 17.3 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH62173.1 - 0.096 12.8 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UDPGP PF01704.13 CCH62174.1 - 3e-189 628.8 0.0 3.6e-189 628.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 CCH62174.1 - 0.014 13.9 0.1 0.034 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Zn_clus PF00172.13 CCH62175.1 - 2.2e-08 33.8 8.9 4.3e-08 32.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.14 CCH62176.1 - 1.8e-17 64.0 0.1 3.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease CBP4 PF07960.6 CCH62176.1 - 0.73 9.4 9.3 3.7 7.1 7.0 1.7 2 0 0 2 2 2 0 CBP4 GAGA_bind PF06217.7 CCH62176.1 - 2.1 8.2 6.4 2.7 7.8 4.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Cpn60_TCP1 PF00118.19 CCH62177.1 - 1e-136 456.3 2.1 1.2e-136 456.2 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RPN7 PF10602.4 CCH62177.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Transposase_23 PF03017.9 CCH62177.1 - 0.087 12.3 0.0 0.25 10.8 0.0 1.7 1 0 0 1 1 1 0 TNP1/EN/SPM transposase COG6 PF06419.6 CCH62179.1 - 2.3e-136 455.4 37.6 2.3e-136 455.4 26.1 1.5 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Diphthamide_syn PF01866.12 CCH62180.1 - 5.1e-114 380.6 0.1 6.2e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.10 CCH62181.1 - 7.3e-72 240.7 3.9 1.2e-71 240.1 2.7 1.3 1 0 0 1 1 1 1 SHQ1 protein DUF2722 PF10846.3 CCH62182.1 - 2.1e-25 89.6 46.1 1e-22 80.7 31.9 3.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) PRA1 PF03208.14 CCH62183.1 - 4.5e-41 139.7 0.4 5.2e-41 139.5 0.3 1.1 1 0 0 1 1 1 1 PRA1 family protein Peptidase_M1 PF01433.15 CCH62184.1 - 1.6e-84 284.2 0.1 2.4e-84 283.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CCH62184.1 - 1.4e-46 157.6 0.4 2.8e-46 156.6 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CCH62184.1 - 1.8e-14 53.9 0.1 2.7e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M64 PF09471.5 CCH62184.1 - 0.041 13.5 0.1 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M61 PF05299.7 CCH62184.1 - 0.2 11.6 2.3 1.4 8.8 1.6 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PH PF00169.24 CCH62185.1 - 9.7e-16 57.8 1.0 9.7e-16 57.8 0.7 3.1 2 1 0 2 2 2 1 PH domain 6PF2K PF01591.13 CCH62186.1 - 1.8e-77 259.3 4.7 3.5e-77 258.4 3.3 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCH62186.1 - 8.5e-25 87.6 0.0 2.7e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CCH62186.1 - 1.4e-07 32.3 0.1 4.6e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH62186.1 - 2e-06 27.7 0.1 7.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCH62186.1 - 1.3e-05 24.3 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CCH62186.1 - 0.00053 20.2 2.4 0.00078 19.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain Pox_A28 PF04584.9 CCH62186.1 - 0.0033 17.3 0.3 0.0095 15.8 0.2 1.8 1 0 0 1 1 1 1 Poxvirus A28 family APS_kinase PF01583.15 CCH62186.1 - 0.016 14.8 0.0 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Sec23_trunk PF04811.10 CCH62187.1 - 2.5e-66 223.5 0.0 4.8e-66 222.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCH62187.1 - 1.5e-22 78.9 3.2 2.6e-22 78.1 0.3 2.7 4 0 0 4 4 4 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CCH62187.1 - 5.7e-19 67.4 5.1 1.1e-18 66.5 3.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCH62187.1 - 2.9e-16 59.7 0.2 1e-15 58.0 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCH62187.1 - 4.6e-10 39.0 0.0 1.2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Ank_2 PF12796.2 CCH62189.1 - 7.6e-63 208.8 2.9 5.4e-23 81.1 0.3 3.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCH62189.1 - 1.2e-35 119.5 2.9 1.3e-10 40.4 0.1 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CCH62189.1 - 1.2e-31 108.5 6.6 8.1e-11 42.1 0.1 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCH62189.1 - 1.7e-29 101.1 1.1 5e-08 32.9 0.2 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH62189.1 - 4.1e-28 94.6 0.7 1.2e-07 31.2 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat DSPc PF00782.15 CCH62190.1 - 2.4e-35 121.0 1.7 2.4e-35 121.0 1.2 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCH62190.1 - 1.4e-05 24.5 0.8 2.6e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCH62190.1 - 0.034 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate Vac7 PF12751.2 CCH62191.1 - 2.5e-20 72.6 4.9 1.2e-14 53.9 0.1 5.3 5 1 0 5 5 5 2 Vacuolar segregation subunit 7 MFS_1 PF07690.11 CCH62193.1 - 3.1e-36 124.8 23.5 5.9e-36 123.8 15.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH62193.1 - 1.6e-13 50.0 14.9 1.6e-13 50.0 10.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter SUN PF03856.8 CCH62195.1 - 7.9e-107 356.1 18.6 7.9e-107 356.1 12.9 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) adh_short PF00106.20 CCH62196.1 - 2e-26 92.9 0.0 3.6e-26 92.0 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCH62196.1 - 3.9e-16 59.5 0.0 5.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCH62196.1 - 3.9e-08 33.0 0.0 2.3e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCH62196.1 - 8.9e-08 31.9 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCH62196.1 - 0.00023 21.2 0.0 0.00062 19.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CCH62196.1 - 0.0015 18.2 0.4 0.0096 15.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CCH62196.1 - 0.028 13.5 0.0 0.55 9.3 0.0 2.5 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 CCH62196.1 - 0.071 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain SNF2_N PF00176.18 CCH62197.1 - 1.1e-83 280.4 0.1 1.1e-83 280.4 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CCH62197.1 - 2.3e-21 75.4 0.3 2.3e-20 72.2 0.5 2.5 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 CCH62197.1 - 2.2e-19 69.0 0.0 6.8e-18 64.3 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 CCH62197.1 - 3.4e-12 46.3 0.7 3.4e-12 46.3 0.5 4.6 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 CCH62197.1 - 0.0018 17.9 7.3 0.0018 17.9 5.1 3.1 2 0 0 2 2 2 1 HSA QLQ PF08880.6 CCH62197.1 - 0.045 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 QLQ MMS19_N PF14500.1 CCH62198.1 - 2.3e-81 272.9 20.9 7.2e-81 271.2 3.9 4.1 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 CCH62198.1 - 2e-80 270.5 26.6 2e-80 270.5 18.4 3.4 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Ipi1_N PF12333.3 CCH62198.1 - 9.4e-06 25.5 1.1 0.16 11.9 0.0 4.6 4 0 0 4 4 4 2 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 CCH62198.1 - 0.0041 17.3 0.0 0.18 12.0 0.0 3.4 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 CCH62198.1 - 0.02 14.9 1.0 0.4 10.8 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat VHS PF00790.14 CCH62198.1 - 0.054 13.1 1.5 0.23 11.0 0.0 2.9 3 0 0 3 3 3 0 VHS domain Vac14_Fab1_bd PF12755.2 CCH62198.1 - 0.08 13.3 6.9 0.6 10.5 0.0 4.9 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region Fungal_trans PF04082.13 CCH62199.1 - 7.8e-32 110.1 5.5 7.8e-32 110.1 3.8 3.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH62199.1 - 9.7e-12 44.6 11.5 2.1e-11 43.5 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fork_head PF00250.13 CCH62200.1 - 6.7e-34 115.7 1.0 6.7e-34 115.7 0.7 2.2 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 CCH62200.1 - 4.3e-06 26.7 0.0 3.4e-05 23.8 0.0 2.7 1 1 1 2 2 2 1 FHA domain Ribosomal_L13 PF00572.13 CCH62201.1 - 6.3e-26 90.9 0.1 1.2e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Mito_carr PF00153.22 CCH62202.1 - 2.2e-65 216.3 3.7 2.4e-22 78.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4509 PF14970.1 CCH62203.1 - 0.027 14.1 0.4 0.027 14.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4509) Med21 PF11221.3 CCH62203.1 - 0.043 13.7 3.8 0.36 10.8 0.2 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex DUF749 PF05370.6 CCH62203.1 - 3.6 7.6 9.3 2.5 8.0 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF749) 2-oxoacid_dh PF00198.18 CCH62204.1 - 2.9e-71 239.4 0.2 3.8e-71 239.0 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CCH62204.1 - 6.5e-15 54.4 0.1 1.5e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 CCH62204.1 - 4.7e-13 48.5 0.0 1.6e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Brix PF04427.13 CCH62205.1 - 8e-45 152.8 0.9 1e-44 152.4 0.6 1.1 1 0 0 1 1 1 1 Brix domain DUF2119 PF09892.4 CCH62205.1 - 0.088 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) DUF1752 PF08550.5 CCH62206.1 - 2e-08 33.6 1.5 2e-08 33.6 1.0 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DUF2413 PF10310.4 CCH62207.1 - 2.8 6.6 7.4 1.9 7.2 4.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2413) HSF_DNA-bind PF00447.12 CCH62208.1 - 3.5e-35 120.2 4.7 6.9e-35 119.3 3.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1633 PF07794.6 CCH62208.1 - 0.012 13.6 1.3 0.017 13.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Viral_env_E26 PF11050.3 CCH62208.1 - 0.092 11.9 2.3 0.17 11.0 1.6 1.4 1 0 0 1 1 1 0 Virus envelope protein E26 Mucin PF01456.12 CCH62208.1 - 1.4 8.6 28.0 0.38 10.5 5.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-TFIIIC PF12660.2 CCH62209.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Ribosomal_S16 PF00886.14 CCH62211.1 - 6.2e-24 83.4 0.1 9.1e-24 82.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 Nucleoporin_FG PF13634.1 CCH62212.1 - 1e-34 119.1 150.0 4.3e-11 43.0 19.0 4.2 1 1 3 4 4 4 4 Nucleoporin FG repeat region zf-C4H2 PF10146.4 CCH62212.1 - 3.3e-05 24.0 2.3 5.9e-05 23.1 1.6 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein DUF1664 PF07889.7 CCH62212.1 - 0.1 12.3 4.8 0.13 12.0 0.9 2.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Alpha-2-MRAP_C PF06401.6 CCH62212.1 - 2.1 8.1 6.7 0.54 10.0 0.2 2.3 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain XRN_N PF03159.13 CCH62213.1 - 2e-100 335.0 3.4 6.8e-100 333.3 0.1 2.7 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Mito_carr PF00153.22 CCH62214.1 - 1e-75 249.5 0.2 1.3e-26 92.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein MRG PF05712.8 CCH62215.1 - 1.5e-45 154.4 0.4 2.7e-45 153.6 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 CCH62215.1 - 3.5e-07 29.8 0.3 1.1e-06 28.1 0.2 1.9 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Macoilin PF09726.4 CCH62215.1 - 0.12 10.6 4.7 0.16 10.2 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 CCH62215.1 - 0.3 11.1 6.5 2.2 8.3 0.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1180 PF06679.7 CCH62215.1 - 5.6 6.8 6.2 23 4.8 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 CCH62216.1 - 2.4e-29 102.2 0.0 3.7e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62216.1 - 2.1e-10 40.1 0.0 3.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3354 PF11834.3 CCH62216.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) HECT PF00632.20 CCH62217.1 - 6.9e-93 311.2 0.0 9.9e-93 310.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CCH62217.1 - 5.3e-34 115.7 19.7 7e-11 41.7 1.0 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CCH62217.1 - 2.6e-16 59.2 0.3 6.7e-16 57.9 0.2 1.8 1 0 0 1 1 1 1 C2 domain GalKase_gal_bdg PF10509.4 CCH62218.1 - 4.9e-21 73.7 0.0 1.4e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCH62218.1 - 2.4e-16 59.5 0.2 5.8e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCH62218.1 - 2.4e-11 43.6 0.0 5.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal ABC2_membrane PF01061.19 CCH62219.1 - 2.4e-70 235.9 61.7 4.6e-41 140.2 10.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCH62219.1 - 5.2e-38 128.8 8.6 1.5e-32 111.3 0.0 4.1 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 CCH62219.1 - 2.8e-37 128.0 0.0 8.2e-19 68.2 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CCH62219.1 - 4.6e-11 42.3 9.9 4.6e-11 42.3 6.8 3.7 3 2 0 3 3 2 1 ABC-2 family transporter protein ABC_trans_N PF14510.1 CCH62219.1 - 9.7e-10 38.4 0.1 4.2e-09 36.3 0.1 2.1 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCH62219.1 - 6.1e-06 25.7 0.0 0.0034 16.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCH62219.1 - 7.8e-06 25.1 0.0 0.00063 18.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CCH62219.1 - 9.7e-05 21.6 0.2 0.37 9.9 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain cobW PF02492.14 CCH62219.1 - 0.00027 20.4 0.2 0.0006 19.3 0.0 1.6 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CCH62219.1 - 0.00036 20.6 0.1 0.01 15.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCH62219.1 - 0.00056 19.9 0.1 0.015 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CCH62219.1 - 0.0012 18.2 0.3 0.024 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH62219.1 - 0.0014 18.6 0.0 1.2 9.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 CCH62219.1 - 0.0022 17.6 0.6 0.053 13.1 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CCH62219.1 - 0.0051 17.1 0.0 0.021 15.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 CCH62219.1 - 0.0066 16.9 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 CCH62219.1 - 0.0077 16.3 0.2 4.2 7.5 0.0 3.7 3 0 0 3 3 3 1 RNA helicase FtsK_SpoIIIE PF01580.13 CCH62219.1 - 0.014 14.8 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCH62219.1 - 0.024 14.5 0.0 0.31 11.0 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 CCH62219.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CCH62219.1 - 0.081 12.7 0.0 0.39 10.5 0.0 2.2 1 0 0 1 1 1 0 Dynamin family AAA_17 PF13207.1 CCH62219.1 - 0.091 13.5 0.0 0.36 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCH62219.1 - 0.12 11.9 0.4 0.47 10.0 0.1 2.1 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 CCH62219.1 - 0.21 11.1 0.1 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Transp_cyt_pur PF02133.10 CCH62220.1 - 4.8e-172 572.4 43.9 5.6e-172 572.2 30.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Chitin_synth_1 PF01644.12 CCH62221.1 - 1.4e-75 252.6 0.3 2.1e-75 251.9 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCH62221.1 - 2e-26 91.4 0.1 4.1e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCH62221.1 - 1.5e-20 73.0 8.9 7.5e-18 64.2 0.6 3.0 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCH62221.1 - 1.9e-09 37.5 1.4 1.9e-09 37.5 1.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCH62221.1 - 3.1e-09 36.9 0.0 1e-08 35.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 KIX PF02172.11 CCH62221.1 - 0.016 15.2 0.3 0.034 14.1 0.2 1.5 1 0 0 1 1 1 0 KIX domain CD34_antigen PF06365.7 CCH62221.1 - 0.23 11.1 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SCO1-SenC PF02630.9 CCH62222.1 - 9.5e-62 207.6 0.1 1.4e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC YchF-GTPase_C PF06071.8 CCH62223.1 - 6.5e-37 125.1 0.4 1.7e-36 123.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCH62223.1 - 8e-13 48.3 0.0 4.1e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CCH62223.1 - 0.0003 20.5 0.0 0.00075 19.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCH62223.1 - 0.01 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B BetaGal_dom3 PF13363.1 CCH62223.1 - 0.021 14.2 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 MobB PF03205.9 CCH62223.1 - 0.077 12.6 0.5 6.2 6.5 0.0 2.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SecA_PP_bind PF01043.15 CCH62223.1 - 0.079 13.3 0.6 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain Cupin_2 PF07883.6 CCH62223.1 - 0.09 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain PhaC_N PF07167.8 CCH62223.1 - 0.12 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF3781 PF12636.2 CCH62223.1 - 0.2 11.6 1.1 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) AAA_23 PF13476.1 CCH62223.1 - 0.25 11.6 3.9 1.5 9.0 2.8 2.1 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 CCH62225.1 - 1.4e-08 34.3 0.0 2.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1184 PF06683.6 CCH62225.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) CTP_transf_1 PF01148.15 CCH62226.1 - 1.9e-72 244.0 27.7 2.6e-72 243.5 19.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family SET PF00856.23 CCH62227.1 - 2.6e-09 37.5 0.1 2.4e-05 24.6 0.0 3.3 3 1 0 3 3 3 2 SET domain zf-CCHC PF00098.18 CCH62227.1 - 0.25 11.3 1.4 0.47 10.4 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L4 PF00573.17 CCH62228.1 - 2.4e-47 160.8 1.6 4.3e-47 159.9 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CCH62228.1 - 1.9e-30 104.5 1.7 3.4e-29 100.5 0.6 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Methyltransf_31 PF13847.1 CCH62229.1 - 5.3e-14 52.0 0.1 1e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCH62229.1 - 1.9e-12 46.9 0.0 3.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCH62229.1 - 6.7e-10 39.5 0.0 2.7e-09 37.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH62229.1 - 2.9e-09 36.9 0.0 6.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCH62229.1 - 4.3e-08 32.2 0.0 5.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.7 CCH62229.1 - 5.2e-08 33.2 0.0 1.5e-07 31.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCH62229.1 - 2.6e-07 30.4 0.0 4.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCH62229.1 - 5.8e-07 29.0 0.1 1.2e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 CCH62229.1 - 8.5e-06 24.9 0.0 1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 CCH62229.1 - 2.5e-05 23.4 0.1 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CCH62229.1 - 2.7e-05 24.4 0.0 9.2e-05 22.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CCH62229.1 - 6.1e-05 22.5 0.2 0.0001 21.8 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 CCH62229.1 - 0.00026 21.3 0.1 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CCH62229.1 - 0.00038 20.5 0.0 0.002 18.1 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 CCH62229.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CCH62229.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 CCH62229.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 CCH62229.1 - 0.021 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 CCH62229.1 - 0.031 13.4 0.1 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB DOT1 PF08123.8 CCH62229.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.1 CCH62229.1 - 0.12 13.2 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CCH62229.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Sld5 PF05916.6 CCH62230.1 - 2.4e-12 47.0 0.0 3.8e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Peptidase_M2 PF01401.13 CCH62230.1 - 0.019 13.2 0.8 0.025 12.8 0.6 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme DUF3016 PF11454.3 CCH62230.1 - 0.023 14.3 0.4 0.073 12.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) FliE PF02049.13 CCH62230.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE DUF2533 PF10752.4 CCH62230.1 - 0.16 12.2 1.8 0.23 11.7 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) DASH_Dad3 PF08656.5 CCH62230.1 - 0.59 9.8 3.5 0.81 9.4 0.0 2.7 3 1 0 3 3 3 0 DASH complex subunit Dad3 PNPOx_C PF10590.4 CCH62232.1 - 3.8e-20 71.0 3.0 7.4e-20 70.1 2.0 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CCH62232.1 - 1.8e-11 43.8 0.0 2.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CRCB PF02537.10 CCH62233.1 - 4.2e-34 116.9 8.9 1.1e-19 70.4 1.6 2.5 2 0 0 2 2 2 2 CrcB-like protein ATP-synt PF00231.14 CCH62234.1 - 3.7e-67 226.6 7.4 4.3e-67 226.5 5.1 1.0 1 0 0 1 1 1 1 ATP synthase AMP-binding PF00501.23 CCH62235.1 - 1.3e-65 221.4 0.0 1.6e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GCV_T PF01571.16 CCH62236.1 - 6.8e-64 215.1 0.0 8.6e-64 214.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCH62236.1 - 2.2e-13 50.0 0.0 3.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 CCH62236.1 - 0.062 13.2 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 GTP-binding protein TrmE N-terminus FANCI_S4 PF14678.1 CCH62236.1 - 0.13 11.3 0.1 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 SNF2_N PF00176.18 CCH62237.1 - 0.4 9.4 4.6 0.73 8.5 3.2 1.6 1 1 0 1 1 1 0 SNF2 family N-terminal domain Atg31 PF09795.4 CCH62238.1 - 1e-33 116.3 9.9 1.2e-33 116.1 6.9 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 tRNA-synt_2b PF00587.20 CCH62239.1 - 5.8e-35 120.4 0.2 1.2e-34 119.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCH62239.1 - 6.2e-20 71.2 9.1 6.2e-20 71.2 6.3 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain IL22 PF14565.1 CCH62240.1 - 0.074 13.1 3.0 4.6 7.3 0.1 3.4 3 0 0 3 3 3 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor Ribosomal_S17 PF00366.15 CCH62241.1 - 8.9e-30 102.5 4.1 1.4e-29 101.8 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Myb_DNA-binding PF00249.26 CCH62242.1 - 1.3e-18 66.8 16.8 9.5e-12 44.7 0.8 5.1 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH62242.1 - 9.5e-18 64.0 19.0 4.8e-14 52.2 2.9 4.3 4 0 0 4 4 4 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 CCH62242.1 - 5.5 7.2 14.1 0.46 10.7 1.3 4.1 4 1 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1752 PF08550.5 CCH62244.1 - 7.7e-08 31.7 2.5 1.8e-07 30.6 1.7 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WD40 PF00400.27 CCH62245.1 - 1.6e-13 49.9 1.8 1.2e-06 28.1 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Pet191_N PF10203.4 CCH62246.1 - 0.00034 20.5 9.9 0.0041 17.1 4.7 2.3 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CCH62246.1 - 0.01 15.5 9.9 0.015 15.0 1.4 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 CCH62246.1 - 0.012 15.4 11.0 0.092 12.6 0.9 3.3 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0203) OS-D PF03392.8 CCH62246.1 - 0.048 13.6 10.3 0.15 12.0 0.7 2.2 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D COX6B PF02297.12 CCH62246.1 - 0.052 13.5 10.8 0.71 9.9 4.2 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CCH62246.1 - 0.077 12.9 12.0 0.87 9.5 1.6 3.1 2 1 1 3 3 3 0 CHCH domain COX17 PF05051.8 CCH62246.1 - 0.88 9.6 8.2 0.86 9.6 0.9 2.9 2 1 0 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.6 CCH62246.1 - 0.99 9.5 5.2 5.5 7.2 1.1 2.6 1 1 2 3 3 3 0 GCK domain PFEMP PF03011.10 CCH62246.1 - 2 8.7 11.5 20 5.5 3.6 2.1 1 1 1 2 2 2 0 PFEMP DBL domain Flavodoxin_1 PF00258.20 CCH62247.1 - 8.4e-09 35.5 0.0 1.4e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 CCH62247.1 - 1.8e-07 30.7 0.0 2.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CCH62247.1 - 3.9e-05 23.2 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Inositol_P PF00459.20 CCH62248.1 - 1e-52 179.0 0.0 1.6e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family AA_permease PF00324.16 CCH62249.1 - 8.4e-117 390.4 39.6 1e-116 390.1 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH62249.1 - 5e-31 107.6 41.8 6.1e-31 107.3 28.3 1.5 1 1 0 1 1 1 1 Amino acid permease Phtf-FEM1B_bdg PF12129.3 CCH62249.1 - 1.4 8.2 4.8 4.8 6.5 3.3 1.8 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Coprogen_oxidas PF01218.13 CCH62250.1 - 6.6e-124 412.2 0.0 7.6e-124 412.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Nuf2 PF03800.9 CCH62252.1 - 1e-27 96.9 1.6 1e-27 96.9 1.1 2.9 2 1 1 3 3 3 1 Nuf2 family KorB PF08535.5 CCH62252.1 - 0.035 14.2 2.1 0.76 9.9 0.2 2.7 2 0 0 2 2 2 0 KorB domain DUF592 PF04574.8 CCH62253.1 - 1.3e-62 209.9 4.7 2.3e-62 209.0 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.12 CCH62253.1 - 3.3e-48 163.7 0.0 1.1e-47 162.0 0.0 1.9 2 0 0 2 2 2 1 Sir2 family tRNA-Thr_ED PF08915.6 CCH62253.1 - 0.0096 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 1 Archaea-specific editing domain of threonyl-tRNA synthetase PseudoU_synth_2 PF00849.17 CCH62254.1 - 2.5e-30 105.4 0.7 4.4e-30 104.6 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 CCH62254.1 - 4.3e-16 58.4 0.0 8.6e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Git3 PF11710.3 CCH62255.1 - 1.6e-71 240.0 14.2 1.6e-71 240.0 9.8 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CCH62255.1 - 4.4e-31 106.4 1.3 1.1e-30 105.2 0.9 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term SNF2_N PF00176.18 CCH62256.1 - 2.1e-61 207.3 1.4 2.5e-61 207.1 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH62256.1 - 1.1e-11 44.3 0.0 8.5e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH62256.1 - 9.3e-08 31.7 0.0 2.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCH62256.1 - 2.7e-07 30.6 0.0 1.5e-06 28.1 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_12 PF13087.1 CCH62256.1 - 0.0059 16.0 0.2 0.02 14.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain ApoB100_C PF12491.3 CCH62256.1 - 0.014 15.0 0.1 2.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal DUF2075 PF09848.4 CCH62256.1 - 0.041 12.8 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Helicase_C_4 PF13871.1 CCH62256.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Helicase_C-like AAA_22 PF13401.1 CCH62256.1 - 0.05 13.7 0.1 0.43 10.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2439 PF10382.4 CCH62256.1 - 0.073 13.2 1.0 0.52 10.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2439) Ank_2 PF12796.2 CCH62257.1 - 0.0035 17.6 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-C2H2_2 PF12756.2 CCH62257.1 - 0.02 14.9 0.3 0.054 13.5 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank PF00023.25 CCH62257.1 - 0.027 14.2 0.1 0.069 12.9 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 CCH62257.1 - 0.095 12.9 0.2 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat zf-C2H2_6 PF13912.1 CCH62257.1 - 0.3 11.0 2.3 8.1 6.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger URO-D PF01208.12 CCH62258.1 - 4.3e-122 407.3 0.0 4.8e-122 407.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.12 CCH62259.1 - 7.1e-31 107.3 0.0 1.3e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCH62259.1 - 3.6e-07 29.8 0.0 1.7e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CCH62259.1 - 0.00022 20.0 0.0 0.0015 17.4 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase DUF4451 PF14616.1 CCH62260.1 - 4.9e-05 23.0 3.1 0.0021 17.8 0.6 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4451) zf-C2H2 PF00096.21 CCH62261.1 - 7e-08 32.3 14.1 8.8e-05 22.6 3.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62261.1 - 0.00023 21.2 11.8 0.017 15.4 2.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62261.1 - 0.00044 20.3 15.8 0.00052 20.1 0.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CCH62261.1 - 0.0014 18.7 1.4 0.0014 18.7 0.9 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCH62261.1 - 0.018 15.1 1.9 0.018 15.1 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CCH62261.1 - 1.8 8.9 12.3 0.84 10.0 1.9 3.4 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Dfp1_Him1_M PF08630.5 CCH62262.1 - 6.4e-41 139.0 1.0 6.4e-41 139.0 0.7 2.9 4 0 0 4 4 4 1 Dfp1/Him1, central region zf-DBF PF07535.7 CCH62262.1 - 2.1e-19 68.9 0.9 4.3e-19 67.9 0.6 1.5 1 0 0 1 1 1 1 DBF zinc finger AlgF PF11182.3 CCH62263.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF TT_ORF1 PF02956.9 CCH62263.1 - 5.9 5.2 7.9 7.3 4.9 5.5 1.0 1 0 0 1 1 1 0 TT viral orf 1 UQ_con PF00179.21 CCH62264.1 - 1.7e-43 147.4 0.0 2.6e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH62264.1 - 0.021 14.5 0.0 0.073 12.8 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B DUF3977 PF13122.1 CCH62265.1 - 0.096 12.5 1.1 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3977) AAA PF00004.24 CCH62266.1 - 7.2e-51 171.8 0.1 1.1e-38 132.4 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCH62266.1 - 2.2e-16 59.5 0.0 5.6e-15 55.0 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 CCH62266.1 - 2e-11 43.3 1.3 1.2e-10 40.8 0.2 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 CCH62266.1 - 1.9e-09 37.7 1.0 0.00041 20.4 0.2 3.6 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCH62266.1 - 2.4e-08 34.7 0.1 0.015 16.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCH62266.1 - 7.9e-08 32.5 0.0 0.016 15.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_19 PF13245.1 CCH62266.1 - 1e-07 31.5 0.2 0.0036 17.0 0.1 2.7 3 0 0 3 3 2 2 Part of AAA domain TIP49 PF06068.8 CCH62266.1 - 1.4e-07 30.5 0.2 0.011 14.4 0.0 2.6 2 1 1 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 CCH62266.1 - 1.2e-06 28.4 0.1 0.01 15.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCH62266.1 - 1.7e-06 27.7 0.1 0.0024 17.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CCH62266.1 - 3.3e-06 27.4 0.1 0.0082 16.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 CCH62266.1 - 3.8e-06 26.4 0.3 0.047 13.0 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 CCH62266.1 - 5.9e-06 26.2 0.0 0.00077 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CCH62266.1 - 6e-06 25.5 0.1 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCH62266.1 - 1e-05 25.4 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CCH62266.1 - 1.2e-05 24.4 0.3 0.068 12.1 0.1 3.3 3 1 1 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CCH62266.1 - 1.2e-05 24.6 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 CCH62266.1 - 1.7e-05 25.1 0.9 0.039 14.2 0.1 2.8 2 1 0 2 2 2 2 ABC transporter RNA_helicase PF00910.17 CCH62266.1 - 2.5e-05 24.3 0.0 0.079 13.1 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Sigma54_activat PF00158.21 CCH62266.1 - 0.00014 21.4 0.0 0.33 10.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 CCH62266.1 - 0.0002 21.0 0.1 0.64 9.6 0.0 3.5 3 0 0 3 3 3 1 Bacterial dnaA protein NACHT PF05729.7 CCH62266.1 - 0.00022 20.9 0.9 0.77 9.4 0.0 3.4 3 0 0 3 3 3 2 NACHT domain Arch_ATPase PF01637.13 CCH62266.1 - 0.00031 20.5 1.1 1.5 8.4 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 CCH62266.1 - 0.00044 19.1 0.0 0.78 8.5 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain AAA_25 PF13481.1 CCH62266.1 - 0.00061 19.2 4.0 2.5 7.4 0.1 3.9 3 1 0 4 4 4 2 AAA domain AAA_10 PF12846.2 CCH62266.1 - 0.00076 19.0 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 CCH62266.1 - 0.00097 18.2 0.0 0.62 9.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF2075 PF09848.4 CCH62266.1 - 0.0012 17.8 0.0 0.062 12.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CCH62266.1 - 0.0016 18.3 0.1 1.1 9.0 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CCH62266.1 - 0.0027 17.3 3.7 0.45 10.0 0.3 3.3 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 CCH62266.1 - 0.0031 16.6 1.0 0.28 10.2 0.1 2.9 3 0 0 3 3 3 1 KaiC AAA_11 PF13086.1 CCH62266.1 - 0.0041 16.7 0.4 2.6 7.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCH62266.1 - 0.0055 16.2 0.9 0.19 11.2 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain UPF0079 PF02367.12 CCH62266.1 - 0.0066 16.0 0.1 2.7 7.6 0.0 3.1 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 CCH62266.1 - 0.01 14.7 0.0 1.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 CCH62266.1 - 0.01 16.1 8.1 0.81 9.9 0.2 2.9 2 2 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CCH62266.1 - 0.013 15.0 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCH62266.1 - 0.014 15.3 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CCH62266.1 - 0.014 15.4 0.2 13 5.8 0.1 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 CCH62266.1 - 0.032 13.7 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 CCH62266.1 - 0.11 11.6 0.1 0.88 8.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase TEA PF01285.13 CCH62268.1 - 1.9e-35 122.8 5.6 1.9e-35 122.8 3.9 2.5 1 1 0 2 2 2 1 TEA/ATTS domain family Ribosomal_60s PF00428.14 CCH62268.1 - 0.0059 16.9 0.8 0.0059 16.9 0.6 2.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein Hyccin PF09790.4 CCH62269.1 - 0.043 12.6 0.0 0.074 11.8 0.0 1.3 1 0 0 1 1 1 0 Hyccin LSM PF01423.17 CCH62270.1 - 3.4e-17 61.7 1.6 3.9e-17 61.5 1.1 1.0 1 0 0 1 1 1 1 LSM domain DUF3835 PF12927.2 CCH62272.1 - 7.1e-15 55.7 0.1 7.1e-15 55.7 0.1 8.9 7 3 1 9 9 9 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 CCH62272.1 - 2.1e-07 30.6 1.8 2.1e-07 30.6 1.2 4.4 5 1 0 5 5 5 1 Prefoldin subunit MRP-S24 PF14955.1 CCH62272.1 - 7.8 6.3 8.6 5.7 6.7 0.4 3.2 2 1 1 3 3 3 0 Mitochondrial ribosome subunit S24 EPL1 PF10513.4 CCH62273.1 - 1.2e-29 103.6 5.3 1.2e-29 103.6 3.6 5.5 3 2 1 4 4 4 1 Enhancer of polycomb-like PGAP1 PF07819.8 CCH62274.1 - 3.2e-87 291.8 0.0 4.9e-87 291.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCH62274.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH62274.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 CCH62274.1 - 0.0021 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CCH62274.1 - 0.0024 17.7 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CCH62274.1 - 0.022 14.0 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.6 CCH62274.1 - 0.024 13.7 0.1 5.2 6.0 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CCH62274.1 - 0.039 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) Patatin PF01734.17 CCH62274.1 - 0.068 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Patatin-like phospholipase Phage_capsid PF05065.8 CCH62274.1 - 0.087 12.0 0.1 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family RabGAP-TBC PF00566.13 CCH62275.1 - 7.6e-21 74.5 10.6 2.9e-20 72.6 7.3 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 CCH62276.1 - 2.3e-12 46.2 1.0 0.0066 16.2 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat SHMT PF00464.14 CCH62277.1 - 4.9e-208 690.3 0.0 5.7e-208 690.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 CCH62277.1 - 7.7e-09 34.9 0.0 1.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCH62277.1 - 1.7e-06 27.0 0.0 2.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCH62277.1 - 0.00016 20.9 0.0 0.00049 19.3 0.0 1.8 1 1 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCH62278.1 - 1.7e-23 82.9 0.0 2.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V bZIP_2 PF07716.10 CCH62279.1 - 1.8e-05 24.4 7.6 4.8e-05 23.1 5.3 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CCH62279.1 - 0.00048 20.0 3.3 0.001 18.9 2.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor DcpS PF05652.7 CCH62279.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.6 2 2 0 2 2 2 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal RNase_T PF00929.19 CCH62280.1 - 1.9e-24 86.7 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Pkinase PF00069.20 CCH62281.1 - 2.5e-61 207.0 0.0 3.6e-38 131.2 0.0 3.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62281.1 - 3.9e-27 94.9 0.0 3.5e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CCH62281.1 - 3.1e-05 23.9 0.1 0.0001 22.2 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CCH62281.1 - 5.6e-05 22.2 0.1 0.0003 19.8 0.0 2.2 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 CCH62281.1 - 0.0017 17.4 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH62281.1 - 0.021 14.5 0.0 0.39 10.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family B3_4 PF03483.12 CCH62282.1 - 4.6e-29 101.1 0.0 7.7e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CCH62282.1 - 1.5e-18 66.3 0.0 4.9e-16 58.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 CCH62282.1 - 0.0032 16.7 0.1 0.037 13.2 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) Ribosomal_L22e PF01776.12 CCH62283.1 - 1.6e-43 147.2 1.3 1.8e-43 147.0 0.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Tfb4 PF03850.9 CCH62283.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Mob1_phocein PF03637.12 CCH62284.1 - 2.9e-71 238.7 1.8 4.9e-71 237.9 1.2 1.4 1 0 0 1 1 1 1 Mob1/phocein family Lin-8 PF03353.10 CCH62284.1 - 0.55 9.4 6.8 0.71 9.0 4.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.8 CCH62284.1 - 7.3 6.3 23.3 10 5.9 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK5_activator PF03261.10 CCH62284.1 - 7.6 5.7 10.7 11 5.2 7.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RNA_pol PF00940.14 CCH62285.1 - 3.8e-166 552.5 0.1 1.5e-165 550.6 0.0 1.9 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CCH62285.1 - 6.7e-85 285.1 1.0 1.2e-84 284.3 0.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Tubulin PF00091.20 CCH62286.1 - 1e-71 241.2 0.0 1.7e-71 240.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCH62286.1 - 7.3e-49 165.0 0.0 1.2e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCH62286.1 - 2.4e-05 24.3 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CCH62286.1 - 0.00075 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MVL PF12151.3 CCH62286.1 - 0.058 13.0 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 Mannan-binding protein MutS_V PF00488.16 CCH62287.1 - 3.6e-62 209.8 0.1 9.8e-62 208.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCH62287.1 - 2.4e-25 89.5 12.0 6e-24 84.9 8.3 2.8 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 CCH62287.1 - 4.8e-13 49.3 0.1 2.7e-12 46.9 0.1 2.4 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCH62287.1 - 8.6e-13 48.2 1.5 8.6e-13 48.2 1.0 4.4 5 0 0 5 5 5 1 MutS family domain IV Toprim PF01751.17 CCH62287.1 - 2.1 8.3 6.0 0.41 10.6 0.1 2.9 3 1 0 3 3 3 0 Toprim domain DUF3437 PF11919.3 CCH62288.1 - 4e-28 96.9 0.0 1.3e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) SMC_N PF02463.14 CCH62289.1 - 5e-58 195.9 41.0 1.5e-34 119.2 3.7 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCH62289.1 - 9.6e-26 90.1 0.1 5.6e-25 87.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 CCH62289.1 - 6.2e-08 32.0 0.1 1.5e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCH62289.1 - 1.2e-06 28.7 1.8 1.2e-06 28.7 1.3 6.4 2 2 1 3 3 3 1 AAA domain SbcCD_C PF13558.1 CCH62289.1 - 0.018 14.9 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit WW PF00397.21 CCH62290.1 - 6.4e-09 35.5 0.9 1.3e-08 34.5 0.6 1.6 1 0 0 1 1 1 1 WW domain PAT1 PF09770.4 CCH62290.1 - 0.032 12.5 31.9 0.035 12.3 22.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 CCH62292.1 - 2.2e-72 238.8 3.7 1.2e-24 85.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.24 CCH62293.1 - 2.1e-26 91.3 11.9 5.1e-09 35.6 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCH62293.1 - 1.3e-19 69.3 13.3 2.7e-08 33.2 0.3 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCH62293.1 - 6.5e-07 28.8 7.5 0.11 12.0 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCH62293.1 - 8.1e-05 22.1 1.9 2.2 7.9 0.0 3.8 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CCH62293.1 - 0.0057 16.4 5.5 0.48 10.2 0.1 3.6 3 0 0 3 3 3 2 NusA-like KH domain Menin PF05053.8 CCH62293.1 - 0.017 13.3 5.2 0.023 12.9 3.6 1.1 1 0 0 1 1 1 0 Menin Mucin PF01456.12 CCH62293.1 - 0.15 11.8 9.9 0.27 10.9 6.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein HMG_CoA_synt_C PF08540.5 CCH62294.1 - 1.2e-103 346.4 5.4 1.6e-103 346.1 3.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CCH62294.1 - 1.6e-92 307.7 0.4 2.6e-92 307.1 0.3 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal COX14 PF14880.1 CCH62297.1 - 3.2e-16 58.6 0.3 4.2e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF1772 PF08592.6 CCH62297.1 - 0.042 13.5 0.0 0.042 13.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) RRM_1 PF00076.17 CCH62298.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH62298.1 - 0.0051 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CCH62298.1 - 0.21 11.3 13.7 1.2 8.9 1.3 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HiaBD2 PF15403.1 CCH62298.1 - 1.1 9.4 5.9 1.6 8.9 2.3 2.3 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) Mito_fiss_reg PF05308.6 CCH62298.1 - 1.2 8.4 3.5 1.6 8.0 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PI-PLC-X PF00388.14 CCH62299.1 - 8.9e-20 70.5 0.0 1.6e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L18ae PF01775.12 CCH62299.1 - 0.094 12.6 0.1 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Ribosomal L18ae/LX protein domain Peptidase_C80 PF11713.3 CCH62299.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 2 0 0 2 2 2 0 Peptidase C80 family DUF3589 PF12141.3 CCH62300.1 - 1.1e-89 300.9 1.4 2.4e-87 293.2 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3589) ABC2_membrane_4 PF12730.2 CCH62300.1 - 0.03 13.4 1.8 0.046 12.8 1.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Oxidored_FMN PF00724.15 CCH62301.1 - 1.4e-115 385.9 0.0 1.6e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Mannosyl_trans3 PF11051.3 CCH62302.1 - 4.1e-64 216.5 1.8 6.2e-64 215.9 1.2 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3119 PF11317.3 CCH62302.1 - 0.031 14.2 0.0 0.15 12.1 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) DUF3589 PF12141.3 CCH62303.1 - 7.1e-14 50.9 23.2 7.9e-08 30.9 6.3 3.8 3 1 0 3 3 3 3 Protein of unknown function (DUF3589) Rotamase_2 PF13145.1 CCH62304.1 - 0.032 14.8 2.0 0.039 14.6 1.0 1.4 1 1 0 1 1 1 0 PPIC-type PPIASE domain FlgI PF02119.11 CCH62304.1 - 1 7.9 8.1 1.1 7.8 5.6 1.0 1 0 0 1 1 1 0 Flagellar P-ring protein DUF572 PF04502.8 CCH62304.1 - 1.3 8.1 8.2 1.6 7.9 5.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mannosyl_trans3 PF11051.3 CCH62306.1 - 3.1e-61 207.0 0.1 4.6e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DnaJ PF00226.26 CCH62307.1 - 0.00016 21.3 0.1 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCH62307.1 - 0.00042 20.1 0.0 0.00065 19.4 0.0 1.2 1 0 0 1 1 1 1 Pam16 Osmo_CC PF08946.5 CCH62307.1 - 0.56 10.2 2.5 8.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Osmosensory transporter coiled coil zf-DHHC PF01529.15 CCH62308.1 - 5.1e-38 130.1 11.7 5.1e-38 130.1 8.1 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase UBA_e1_C PF09358.5 CCH62309.1 - 0.025 14.7 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Syja_N PF02383.13 CCH62310.1 - 2.7e-91 305.6 0.2 2.7e-91 305.6 0.1 1.8 2 0 0 2 2 2 1 SacI homology domain HTH_CodY PF08222.6 CCH62310.1 - 0.021 14.1 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 0 CodY helix-turn-helix domain LCM PF04072.9 CCH62311.1 - 6.8e-25 87.6 0.0 1.1e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 CCH62311.1 - 6.9e-11 41.7 10.5 2.3e-07 30.4 0.1 5.0 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CCH62311.1 - 4.3e-10 39.3 6.3 0.00011 22.1 0.1 5.1 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CCH62311.1 - 1.4e-09 37.2 4.3 0.00039 20.0 0.1 3.3 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CCH62311.1 - 4.9e-08 32.7 3.5 0.011 15.6 0.0 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 CCH62311.1 - 2.6e-05 24.2 3.2 0.016 15.3 0.0 4.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CCH62311.1 - 8.3 6.0 14.2 1.1 8.8 0.1 4.1 5 0 0 5 5 5 0 Kelch motif CDC50 PF03381.10 CCH62312.1 - 2.7e-90 302.3 2.2 4.5e-90 301.5 1.5 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Aminotran_3 PF00202.16 CCH62313.1 - 1.1e-104 350.0 0.0 1.3e-104 349.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Na_Ca_ex PF01699.19 CCH62314.1 - 3.7e-26 91.3 27.2 6.3e-15 55.0 8.4 3.9 5 1 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CCH62314.1 - 2.5e-07 31.0 1.9 2.5e-07 31.0 1.3 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF307) IF4E PF01652.13 CCH62315.1 - 4.8e-55 185.5 1.5 5.7e-55 185.3 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 CCH62316.1 - 5.9e-17 60.8 3.1 2.9e-07 30.1 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 CCH62316.1 - 3.2e-06 27.1 5.1 8.6e-06 25.7 3.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCH62316.1 - 6.4e-06 25.9 7.9 6.4e-06 25.9 5.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH62316.1 - 8.5e-05 22.5 7.7 8.5e-05 22.5 5.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH62316.1 - 0.0012 18.4 4.5 0.0012 18.4 3.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCH62316.1 - 0.099 12.4 7.6 0.23 11.3 5.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CCH62316.1 - 0.46 10.2 17.2 0.35 10.6 8.4 2.9 1 1 1 2 2 2 0 zinc-RING finger domain Sugar_tr PF00083.19 CCH62317.1 - 3.3e-111 372.0 27.8 3.7e-111 371.8 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH62317.1 - 2.6e-24 85.6 46.4 9.7e-24 83.7 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 CCH62318.1 - 3.4e-19 68.7 23.6 2.7e-12 46.0 3.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2TM PF13239.1 CCH62318.1 - 1.3 9.1 10.6 0.87 9.6 0.1 3.9 4 0 0 4 4 4 0 2TM domain HAD_2 PF13419.1 CCH62319.1 - 7.1e-17 62.1 0.0 9.1e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH62319.1 - 0.0001 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Lipoprotein_1 PF00820.14 CCH62319.1 - 0.0023 17.0 0.7 0.0038 16.3 0.5 1.3 1 0 0 1 1 1 1 Borrelia lipoprotein DNA_mis_repair PF01119.14 CCH62320.1 - 1.5e-13 50.2 0.3 3.1e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCH62320.1 - 2.3e-08 33.7 0.1 7.2e-08 32.1 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCH62320.1 - 1.2e-07 31.4 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bromodomain PF00439.20 CCH62322.1 - 0.018 14.9 4.7 0.2 11.6 3.3 2.6 1 1 0 1 1 1 0 Bromodomain HA2 PF04408.18 CCH62323.1 - 1.4e-22 79.6 0.0 8.4e-22 77.1 0.0 2.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCH62323.1 - 2.6e-14 52.8 0.0 2.4e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCH62323.1 - 6.2e-11 42.1 0.1 3.3e-10 39.7 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCH62323.1 - 7.6e-08 32.0 0.0 2.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH62323.1 - 2.2e-05 24.5 0.3 0.00022 21.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCH62323.1 - 0.0043 16.1 1.5 0.0073 15.4 0.1 2.1 2 1 0 2 2 2 1 KaiC T2SE PF00437.15 CCH62323.1 - 0.018 13.9 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HTH_37 PF13744.1 CCH62323.1 - 0.061 13.1 1.6 0.25 11.1 0.4 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain MOZ_SAS PF01853.13 CCH62324.1 - 4.9e-61 205.2 2.6 7e-61 204.7 1.8 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-C2H2 PF00096.21 CCH62324.1 - 0.1 12.9 2.3 0.24 11.8 1.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type SNF2_N PF00176.18 CCH62325.1 - 1.6e-68 230.7 0.5 1.6e-68 230.7 0.3 2.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCH62325.1 - 5.6e-11 42.3 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.1 CCH62325.1 - 5.8e-10 38.6 4.8 1.1e-09 37.7 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CCH62325.1 - 1.4e-09 37.6 0.0 3.7e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 CCH62325.1 - 2e-08 34.1 6.9 4e-08 33.1 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH62325.1 - 4.3e-08 32.8 7.2 1e-07 31.6 5.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCH62325.1 - 2e-07 30.5 7.6 4.2e-07 29.5 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH62325.1 - 1.1e-06 28.2 8.0 2.3e-06 27.1 5.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCH62325.1 - 0.00042 20.1 7.8 0.001 18.8 5.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 CCH62325.1 - 0.00051 19.5 7.6 0.0011 18.4 5.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CCH62325.1 - 0.00072 19.6 3.6 0.0017 18.4 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCH62325.1 - 0.0019 18.0 2.1 0.0036 17.1 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CCH62325.1 - 0.0033 17.0 4.5 0.0033 17.0 3.1 2.4 3 0 0 3 3 2 1 RING-type zinc-finger zf-Nse PF11789.3 CCH62325.1 - 1.3 8.5 5.9 2.3 7.7 2.8 2.5 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 CCH62325.1 - 1.3 8.5 7.2 6.2 6.4 5.1 2.0 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger MIF4G_like PF09088.6 CCH62326.1 - 1.1e-58 197.8 1.0 2.9e-58 196.4 0.7 1.8 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CCH62326.1 - 3e-47 160.9 7.4 3e-47 160.9 5.1 2.2 2 0 0 2 2 2 1 MIF4G like Pkr1 PF08636.5 CCH62327.1 - 1.7e-18 66.3 4.0 2.1e-18 66.1 2.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Pox_P21 PF05313.7 CCH62327.1 - 0.0036 16.5 1.4 0.0044 16.3 1.0 1.1 1 0 0 1 1 1 1 Poxvirus P21 membrane protein DcuC PF03606.10 CCH62327.1 - 0.0088 14.3 0.4 0.011 14.0 0.3 1.0 1 0 0 1 1 1 1 C4-dicarboxylate anaerobic carrier FUSC-like PF12805.2 CCH62327.1 - 0.016 14.1 0.3 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF3568 PF12092.3 CCH62327.1 - 0.021 14.5 0.2 0.026 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) MSC PF09402.5 CCH62327.1 - 0.027 13.1 0.1 0.032 12.9 0.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF788 PF05620.6 CCH62327.1 - 0.035 13.9 0.2 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF4094 PF13334.1 CCH62327.1 - 0.17 12.2 0.2 0.17 12.2 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Bap31 PF05529.7 CCH62327.1 - 0.35 10.2 1.9 0.37 10.2 0.1 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF2140 PF09911.4 CCH62327.1 - 0.81 8.8 4.2 0.12 11.5 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) AICARFT_IMPCHas PF01808.13 CCH62328.1 - 4.6e-116 387.3 0.0 6.8e-116 386.7 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCH62328.1 - 3.6e-22 78.1 0.6 7.7e-22 77.0 0.1 1.9 2 0 0 2 2 2 1 MGS-like domain Sdh_cyt PF01127.17 CCH62329.1 - 7.7e-18 64.4 0.4 1e-17 64.1 0.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.20 CCH62330.1 - 4.9e-65 219.2 0.1 1e-64 218.2 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62330.1 - 4.4e-28 98.0 0.1 1.2e-27 96.6 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH62330.1 - 0.028 13.3 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DASH_Hsk3 PF08227.6 CCH62331.1 - 4.1e-06 26.8 4.8 7.2e-06 26.0 3.3 1.6 1 1 0 1 1 1 1 DASH complex subunit Hsk3 like ORF6C PF10552.4 CCH62331.1 - 0.024 14.3 0.5 0.026 14.2 0.3 1.1 1 0 0 1 1 1 0 ORF6C domain DASH_Dad3 PF08656.5 CCH62331.1 - 0.073 12.7 1.8 0.12 12.0 1.3 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad3 Mnd1 PF03962.10 CCH62331.1 - 0.67 9.5 4.1 3.4 7.3 0.3 2.0 1 1 1 2 2 2 0 Mnd1 family UBN2_3 PF14244.1 CCH62332.1 - 0.079 12.5 9.3 0.08 12.4 2.0 2.7 2 1 2 4 4 4 0 gag-polypeptide of LTR copia-type DUF869 PF05911.6 CCH62332.1 - 0.087 11.0 11.9 0.091 10.9 8.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF342 PF03961.8 CCH62332.1 - 0.21 9.9 8.0 0.31 9.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 CCH62332.1 - 0.27 11.3 16.7 0.07 13.2 6.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4559 PF15112.1 CCH62332.1 - 0.28 10.3 15.0 0.39 9.8 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Spc24 PF08286.6 CCH62332.1 - 0.28 10.8 19.6 74 3.0 13.6 3.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HR1 PF02185.11 CCH62332.1 - 0.55 10.0 9.8 0.068 12.9 2.4 2.5 2 1 0 2 2 2 0 Hr1 repeat FemAB PF02388.11 CCH62332.1 - 0.55 8.8 10.2 0.75 8.4 3.9 2.1 2 0 0 2 2 2 0 FemAB family NPV_P10 PF05531.7 CCH62332.1 - 0.69 10.2 16.3 0.86 9.8 5.3 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein IZUMO PF15005.1 CCH62332.1 - 1.1 9.2 4.5 1.5 8.8 2.5 1.6 1 1 0 1 1 1 0 Izumo sperm-egg fusion DUF4140 PF13600.1 CCH62332.1 - 1.3 9.4 7.1 6.9 7.1 1.3 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 CCH62332.1 - 2.3 7.0 12.5 4.6 6.1 8.7 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cep57_MT_bd PF06657.8 CCH62332.1 - 3.3 7.7 10.3 0.91 9.5 0.6 3.1 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 V_ATPase_I PF01496.14 CCH62332.1 - 3.5 5.3 11.5 11 3.6 7.9 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family NYD-SP28 PF14772.1 CCH62332.1 - 9.5 6.3 12.8 0.37 10.9 3.0 2.7 2 1 2 4 4 4 0 Sperm tail L31 PF09784.4 CCH62333.1 - 6.6e-38 128.9 3.4 1.3e-37 127.9 2.3 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Adaptin_N PF01602.15 CCH62334.1 - 1.3e-87 294.3 31.2 1.8e-87 293.9 21.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCH62334.1 - 1.3e-07 31.6 6.6 1.3e-07 31.6 4.6 4.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCH62334.1 - 3.8e-06 26.5 0.0 0.0099 15.8 0.0 3.1 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 CCH62334.1 - 5.4e-06 26.6 0.0 2e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 HEAT repeats Utp12 PF04003.7 CCH62334.1 - 0.037 13.9 1.3 0.31 10.9 0.1 2.7 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF3158 PF11358.3 CCH62334.1 - 0.082 12.3 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) S10_plectin PF03501.10 CCH62335.1 - 0.031 14.1 0.2 0.11 12.4 0.2 1.9 1 0 0 1 1 1 0 Plectin/S10 domain Ribosomal_L5_C PF00673.16 CCH62338.1 - 4.2e-22 77.6 0.2 9.1e-22 76.6 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCH62338.1 - 2.2e-05 24.1 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Flavokinase PF01687.12 CCH62339.1 - 1e-27 96.4 0.0 3.1e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Riboflavin kinase DUF4250 PF14056.1 CCH62339.1 - 0.1 12.3 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Reticulon PF02453.12 CCH62340.1 - 0.0018 17.9 8.8 0.0035 16.9 6.1 1.5 1 1 0 1 1 1 1 Reticulon Sel1 PF08238.7 CCH62341.1 - 4e-23 81.3 8.1 0.0077 16.8 0.2 8.4 7 2 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.1 CCH62341.1 - 0.019 15.3 4.6 43 4.8 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCH62341.1 - 0.069 12.8 8.4 0.064 12.9 0.5 3.7 2 2 1 3 3 3 0 TPR repeat TPR_17 PF13431.1 CCH62341.1 - 2.8 8.3 13.2 13 6.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCH62341.1 - 3.7 7.3 16.5 13 5.6 0.2 5.1 3 1 1 4 4 4 0 Tetratricopeptide repeat SRP1_TIP1 PF00660.12 CCH62342.1 - 5.2e-18 64.7 4.1 5.8e-18 64.6 0.4 3.1 2 0 0 2 2 2 1 Seripauperin and TIP1 family Flocculin_t3 PF13928.1 CCH62342.1 - 0.007 16.4 46.6 0.014 15.5 13.3 9.7 5 4 5 10 10 10 6 Flocculin type 3 repeat Zn_clus PF00172.13 CCH62344.1 - 1.6e-08 34.2 10.5 3.4e-08 33.2 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L10 PF00466.15 CCH62345.1 - 4.1e-05 23.4 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Fimbrillin_C PF15495.1 CCH62345.1 - 0.012 15.7 0.1 0.066 13.3 0.1 2.1 1 1 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal Methyltransf_4 PF02390.12 CCH62346.1 - 2.1e-60 203.1 0.1 3.3e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CCH62346.1 - 9e-07 28.5 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCH62346.1 - 5.1e-05 23.8 0.0 8.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCH62346.1 - 0.00036 20.5 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCH62346.1 - 0.00037 20.8 0.0 0.0059 16.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCH62346.1 - 0.0014 19.0 0.0 0.005 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCH62346.1 - 0.003 16.9 0.0 0.0072 15.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CCH62346.1 - 0.0036 16.4 0.0 0.014 14.5 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3958 PF13125.1 CCH62346.1 - 0.013 15.3 0.1 0.042 13.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Methyltransf_11 PF08241.7 CCH62346.1 - 0.018 15.4 0.0 1.6 9.2 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 CCH62346.1 - 0.025 13.5 0.0 0.086 11.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) DUF2431 PF10354.4 CCH62346.1 - 0.068 13.1 1.0 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) DOT1 PF08123.8 CCH62346.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Histone methylation protein DOT1 Mito_carr PF00153.22 CCH62347.1 - 1.5e-33 114.3 0.8 3.4e-14 52.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ATC_hydrolase PF14196.1 CCH62348.1 - 0.024 15.0 0.2 0.024 15.0 0.1 2.6 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase VIT1 PF01988.14 CCH62350.1 - 1.5e-55 187.9 2.2 1.8e-55 187.7 1.5 1.0 1 0 0 1 1 1 1 VIT family CRF1 PF10380.4 CCH62351.1 - 3.9e-35 120.8 5.2 3.9e-35 120.8 3.6 6.4 4 2 1 5 5 5 1 Transcription factor CRF1 PRKCSH-like PF12999.2 CCH62352.1 - 1.3e-38 132.3 5.3 4e-38 130.7 3.7 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CCH62352.1 - 3.8e-18 65.4 4.6 7.6e-18 64.4 0.3 3.1 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CCH62352.1 - 4.5e-06 27.3 0.6 1.4e-05 25.8 0.4 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein NAAA-beta PF15508.1 CCH62352.1 - 0.11 12.9 2.5 13 6.1 0.1 4.2 3 1 1 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SlyX PF04102.7 CCH62352.1 - 2.5 8.5 7.7 41 4.6 1.7 3.5 3 0 0 3 3 3 0 SlyX Ldl_recept_a PF00057.13 CCH62352.1 - 4.7 7.1 17.6 1 9.3 2.1 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Cyclin_N PF00134.18 CCH62354.1 - 0.0036 16.8 0.5 0.0073 15.8 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain S100PBPR PF15427.1 CCH62354.1 - 0.0088 15.1 4.0 0.016 14.3 2.8 1.4 1 0 0 1 1 1 1 S100P-binding protein Septin PF00735.13 CCH62355.1 - 2.1e-70 236.9 5.0 3.1e-70 236.4 3.5 1.2 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 CCH62355.1 - 2.7e-05 24.0 1.9 5.9e-05 22.9 0.1 2.6 2 2 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CCH62355.1 - 0.00013 21.8 1.1 0.00064 19.6 0.4 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCH62355.1 - 0.00034 20.9 0.8 0.00075 19.8 0.0 1.9 3 0 0 3 3 1 1 ABC transporter AAA_33 PF13671.1 CCH62355.1 - 0.00038 20.3 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CCH62355.1 - 0.00039 20.9 0.3 0.0016 18.9 0.0 2.2 3 0 0 3 3 2 1 Miro-like protein Arch_ATPase PF01637.13 CCH62355.1 - 0.00039 20.2 0.4 0.00039 20.2 0.3 1.9 2 1 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 CCH62355.1 - 0.0033 16.6 0.0 0.0078 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 CCH62355.1 - 0.015 15.1 2.5 0.03 14.2 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCH62355.1 - 0.023 14.1 0.0 0.068 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain Corona_nucleoca PF00937.13 CCH62355.1 - 0.026 13.4 1.7 0.037 12.9 1.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FtsK_SpoIIIE PF01580.13 CCH62355.1 - 0.028 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 CCH62355.1 - 0.034 14.9 0.1 0.15 12.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 CCH62355.1 - 0.034 14.2 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CCH62355.1 - 0.034 13.6 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CCH62355.1 - 0.036 14.2 0.0 0.23 11.6 0.0 2.4 2 1 1 3 3 3 0 RNA helicase DAP3 PF10236.4 CCH62355.1 - 0.044 12.7 0.9 0.36 9.7 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MobB PF03205.9 CCH62355.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCH62355.1 - 0.083 13.1 0.2 0.083 13.1 0.1 2.8 2 1 0 3 3 2 0 AAA domain NACHT PF05729.7 CCH62355.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad9_Rad53_bind PF08605.5 CCH62356.1 - 2.7e-27 95.1 0.8 1e-26 93.2 0.5 2.1 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 CCH62356.1 - 3.6e-08 33.4 1.5 1.1e-07 31.8 0.2 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-H2C2_2 PF13465.1 CCH62357.1 - 4e-06 26.8 10.8 4.4e-05 23.5 4.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCH62357.1 - 5e-05 23.3 17.3 0.0054 16.9 2.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62357.1 - 0.00033 20.7 18.0 0.016 15.4 0.6 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCH62357.1 - 0.051 13.4 7.6 0.023 14.6 1.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 CCH62357.1 - 0.061 13.4 1.3 0.15 12.1 0.9 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CCH62357.1 - 1.2 9.4 4.5 2.1 8.7 0.7 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aha1_N PF09229.6 CCH62358.1 - 5.3e-39 133.1 0.1 9.5e-39 132.3 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CCH62358.1 - 4.5e-06 26.7 0.0 8.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3362 PF11842.3 CCH62358.1 - 0.038 13.8 0.2 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) DUF3439 PF11921.3 CCH62358.1 - 0.069 12.8 1.3 0.14 11.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zn_clus PF00172.13 CCH62359.1 - 6.3e-08 32.4 10.1 1.1e-07 31.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMAP PF15477.1 CCH62359.1 - 8.1 6.7 8.8 14 6.0 3.8 3.2 1 1 0 1 1 1 0 Small acidic protein family Ras PF00071.17 CCH62360.1 - 5.5e-51 172.1 0.0 6.7e-51 171.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH62360.1 - 1.5e-14 54.5 0.0 2.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH62360.1 - 3.4e-07 29.6 0.0 4.6e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Zn_clus PF00172.13 CCH62361.1 - 1.5e-08 34.4 9.5 2.6e-08 33.6 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 CCH62362.1 - 6.2e-17 61.6 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3605 PF12239.3 CCH62362.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) Transp_cyt_pur PF02133.10 CCH62363.1 - 8.8e-73 245.3 38.1 8.8e-73 245.3 26.4 1.3 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.11 CCH62364.1 - 1.2e-29 103.1 25.0 1.2e-29 103.1 17.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCH62364.1 - 3.2e-05 22.6 12.3 3.2e-05 22.6 8.5 2.4 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 CCH62364.1 - 0.0006 18.1 6.6 0.00091 17.5 4.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2754 PF10953.3 CCH62364.1 - 0.005 16.8 0.0 0.02 14.9 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2754) Rick_17kDa_Anti PF05433.10 CCH62364.1 - 0.063 12.9 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain YqhR PF11085.3 CCH62364.1 - 0.16 11.4 6.1 0.55 9.7 4.2 1.9 1 0 0 1 1 1 0 Conserved membrane protein YqhR TraL PF07178.6 CCH62364.1 - 0.66 10.0 4.1 0.45 10.5 0.5 2.5 2 0 0 2 2 2 0 TraL protein Thi4 PF01946.12 CCH62365.1 - 2.1e-97 324.7 0.2 2.5e-97 324.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CCH62365.1 - 5.5e-07 28.8 0.5 4.1e-06 25.9 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCH62365.1 - 2.2e-05 23.5 0.3 3.3e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 CCH62365.1 - 8.1e-05 22.5 0.4 0.00036 20.5 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCH62365.1 - 0.00027 19.9 1.2 0.0042 15.9 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CCH62365.1 - 0.00038 20.2 0.1 0.0012 18.5 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCH62365.1 - 0.0014 18.5 0.0 0.011 15.6 0.3 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH62365.1 - 0.0034 17.4 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCH62365.1 - 0.019 13.4 0.6 0.032 12.6 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 CCH62365.1 - 0.032 13.3 0.1 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Coq4 PF05019.8 CCH62366.1 - 4.1e-92 307.1 0.0 4.9e-92 306.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SMI1_KNR4 PF09346.5 CCH62366.1 - 0.0046 16.9 0.1 0.016 15.2 0.1 1.8 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Rogdi_lz PF10259.4 CCH62367.1 - 1.8e-34 119.0 0.0 1.5e-33 116.1 0.0 2.0 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein Flg_hook PF02120.11 CCH62367.1 - 0.063 12.9 0.4 25 4.6 0.0 3.4 4 0 0 4 4 4 0 Flagellar hook-length control protein FliK DASH_Spc19 PF08287.6 CCH62368.1 - 6.8e-18 64.7 13.1 8.1e-18 64.4 9.1 1.0 1 0 0 1 1 1 1 Spc19 Ctf8 PF09696.5 CCH62368.1 - 0.015 15.0 0.9 0.019 14.7 0.5 1.4 1 1 0 1 1 1 0 Ctf8 Mnd1 PF03962.10 CCH62368.1 - 0.14 11.8 6.2 0.2 11.2 4.3 1.3 1 0 0 1 1 1 0 Mnd1 family DUF342 PF03961.8 CCH62368.1 - 0.38 9.1 7.5 0.48 8.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CHD5 PF04420.9 CCH62368.1 - 0.62 9.7 6.2 1.8 8.1 1.6 2.3 1 1 1 2 2 2 0 CHD5-like protein IncA PF04156.9 CCH62368.1 - 0.74 9.3 13.3 0.99 8.9 9.2 1.3 1 0 0 1 1 1 0 IncA protein Nup54 PF13874.1 CCH62368.1 - 0.98 9.0 9.9 0.32 10.6 2.5 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF465 PF04325.8 CCH62368.1 - 1 9.1 6.0 3.2 7.5 3.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF465) Osmo_CC PF08946.5 CCH62368.1 - 1.1 9.2 4.9 2.1 8.4 0.4 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Striatin PF08232.7 CCH62368.1 - 1.9 8.7 9.9 3.2 8.0 6.9 1.3 1 0 0 1 1 1 0 Striatin family DUF4407 PF14362.1 CCH62368.1 - 4.6 6.1 7.2 5.9 5.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FHA PF00498.21 CCH62369.1 - 4.5e-14 52.3 2.0 1.4e-13 50.7 0.7 2.3 2 0 0 2 2 2 1 FHA domain Apolipoprotein PF01442.13 CCH62369.1 - 0.015 14.7 2.5 0.027 13.9 1.7 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BPL_LplA_LipB PF03099.14 CCH62370.1 - 7.2e-13 48.6 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0104 PF03706.8 CCH62373.1 - 1.4 8.1 12.9 8.2 5.6 9.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) Yip1 PF04893.12 CCH62373.1 - 2.1 7.7 17.3 0.94 8.9 2.8 2.1 2 0 0 2 2 2 0 Yip1 domain OppC_N PF12911.2 CCH62373.1 - 4.9 6.6 0.0 4.9 6.6 0.0 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C PI3Ka PF00613.15 CCH62374.1 - 4.9e-68 227.9 0.0 7.3e-67 224.1 0.0 2.3 1 1 1 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCH62374.1 - 2.6e-46 158.0 0.1 2.2e-44 151.7 0.0 3.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CCH62374.1 - 1.5e-19 70.2 2.2 4.2e-19 68.7 1.5 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Dicer_dimer PF03368.9 CCH62374.1 - 0.029 14.1 0.1 0.56 10.0 0.0 2.8 2 1 0 2 2 2 0 Dicer dimerisation domain TBD PF12845.2 CCH62374.1 - 0.11 12.1 3.3 0.7 9.4 0.3 3.1 2 1 0 2 2 2 0 TBD domain Arv1 PF04161.8 CCH62375.1 - 5.8e-56 189.6 7.9 5.8e-56 189.6 5.5 1.5 2 0 0 2 2 2 1 Arv1-like family TIP49 PF06068.8 CCH62377.1 - 1.4e-187 623.2 0.7 1.7e-187 623.0 0.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCH62377.1 - 1.7e-08 34.7 0.2 8.4e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCH62377.1 - 3.6e-08 32.7 1.8 8.6e-05 21.6 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CCH62377.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCH62377.1 - 0.0016 18.4 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCH62377.1 - 0.0089 15.7 0.2 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CCH62377.1 - 0.011 14.8 0.1 0.027 13.5 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 CCH62377.1 - 0.024 13.8 0.1 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 CCH62377.1 - 0.026 13.4 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.9 CCH62377.1 - 0.026 14.2 0.1 0.86 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.7 CCH62377.1 - 0.044 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 CCH62377.1 - 0.053 12.4 0.2 0.42 9.4 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein Cpn60_TCP1 PF00118.19 CCH62378.1 - 1.7e-144 482.1 1.3 1.9e-144 481.9 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.19 CCH62379.1 - 2.2e-48 164.6 0.1 2.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 CCH62379.1 - 2.5 8.0 12.2 0.67 9.8 3.9 3.0 3 0 0 3 3 3 0 MYND finger zf-DHHC PF01529.15 CCH62381.1 - 1.2e-34 119.2 9.6 1.2e-34 119.2 6.7 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase PRELI PF04707.9 CCH62382.1 - 6.3e-53 178.5 1.3 8.1e-53 178.1 0.9 1.1 1 0 0 1 1 1 1 PRELI-like family M157 PF11624.3 CCH62382.1 - 0.025 13.7 1.1 0.25 10.4 0.1 2.0 1 1 1 2 2 2 0 MHC class I-like protein M157 VirDNA-topo-I_N PF09266.5 CCH62382.1 - 0.047 13.5 0.1 0.18 11.7 0.1 2.0 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal DUF1878 PF08963.5 CCH62382.1 - 0.047 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) Thioredoxin PF00085.15 CCH62384.1 - 3.2e-05 23.5 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Sec10 PF07393.6 CCH62385.1 - 5.1e-186 619.9 26.9 5.1e-186 619.9 18.6 1.3 1 1 1 2 2 2 1 Exocyst complex component Sec10 SAS4 PF15460.1 CCH62386.1 - 6.2e-23 80.5 5.0 6.2e-23 80.5 3.5 2.2 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PCI PF01399.22 CCH62387.1 - 2.1e-05 24.7 0.6 3.3e-05 24.1 0.4 1.5 1 0 0 1 1 1 1 PCI domain DUF1827 PF08860.5 CCH62387.1 - 0.0081 16.2 1.3 0.27 11.3 0.9 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1827) CybS PF05328.7 CCH62388.1 - 1.6e-40 137.8 0.0 2.3e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 CybS DUF3185 PF11381.3 CCH62388.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Peptidase_M16 PF00675.15 CCH62389.1 - 5.2e-52 175.5 0.0 1.2e-51 174.4 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCH62389.1 - 7.2e-39 133.3 0.0 1e-37 129.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain HMG_box PF00505.14 CCH62390.1 - 1.8e-11 44.1 2.1 3.2e-11 43.3 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCH62390.1 - 1.5e-06 28.4 0.6 1.5e-06 28.4 0.4 1.7 2 0 0 2 2 2 1 HMG-box domain PMC2NT PF08066.7 CCH62390.1 - 0.077 13.3 0.2 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain IPK PF03770.11 CCH62391.1 - 1.2e-46 158.8 0.6 1.6e-46 158.4 0.4 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase CENP-B_dimeris PF09026.5 CCH62391.1 - 0.27 11.4 6.8 0.91 9.7 4.7 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 CCH62391.1 - 0.53 9.7 4.5 0.93 8.9 3.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sec7 PF01369.15 CCH62392.1 - 5.8e-67 225.0 0.1 5.8e-67 225.0 0.1 3.5 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 CCH62392.1 - 2.6e-45 153.8 3.3 1.6e-44 151.2 0.7 3.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCH62392.1 - 1.6e-23 82.0 2.1 1.6e-23 82.0 1.5 5.2 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) AMP-binding PF00501.23 CCH62393.1 - 9.9e-87 291.0 0.0 1.2e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCH62393.1 - 3.4e-19 69.5 0.0 9.8e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mem_trans PF03547.13 CCH62394.1 - 5.9e-57 192.7 1.7 3.1e-32 111.3 0.4 2.1 2 0 0 2 2 2 2 Membrane transport protein Stb3 PF10330.4 CCH62395.1 - 2.3e-29 100.9 0.1 5.2e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein CDC37_N PF03234.9 CCH62396.1 - 3e-63 213.3 16.4 3e-63 213.3 11.4 3.9 2 1 2 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CCH62396.1 - 2.3e-48 163.9 8.5 2.3e-48 163.9 5.9 3.3 4 0 0 4 4 4 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CCH62396.1 - 2.3e-24 85.1 4.6 2.3e-24 85.1 3.2 2.8 3 1 0 3 3 3 1 Cdc37 C terminal domain TFIID_30kDa PF03540.8 CCH62397.1 - 8.7e-26 89.5 0.1 1.3e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Sec5 PF15469.1 CCH62398.1 - 4.3e-44 150.4 13.8 4.3e-44 150.4 9.5 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec5 Anti-adapt_IraP PF10796.4 CCH62398.1 - 0.32 11.3 7.6 4 7.8 0.2 4.2 4 0 0 4 4 4 0 Sigma-S stabilisation anti-adaptor protein COG2 PF06148.6 CCH62398.1 - 0.45 10.3 9.5 0.27 11.0 3.1 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4477 PF14780.1 CCH62399.1 - 0.063 12.6 6.7 0.13 11.6 0.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) DUF262 PF03235.9 CCH62399.1 - 5.6 6.8 7.9 15 5.4 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function DUF262 Glyco_hydro_81 PF03639.8 CCH62400.1 - 8.9e-230 764.3 9.3 1.1e-229 764.0 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Sec1 PF00995.18 CCH62401.1 - 9.6e-105 351.3 5.0 1.4e-104 350.8 3.5 1.2 1 0 0 1 1 1 1 Sec1 family Pro_dh PF01619.13 CCH62402.1 - 2.3e-53 181.2 0.1 3.1e-53 180.8 0.1 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Cwf_Cwc_15 PF04889.7 CCH62403.1 - 9.7e-07 28.7 9.5 2.4e-06 27.4 6.6 1.8 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.23 CCH62404.1 - 1.9e-13 49.5 1.0 6.8e-13 47.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCH62404.1 - 7.9e-12 44.5 0.0 3.5e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCH62404.1 - 1.3e-05 24.5 0.0 2.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TPR_2 PF07719.12 CCH62405.1 - 2.9e-05 23.6 0.2 0.011 15.6 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCH62405.1 - 5.8e-05 22.6 0.0 0.0055 16.3 0.0 2.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CCH62405.1 - 0.00032 20.1 2.2 0.019 14.5 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCH62405.1 - 0.0011 19.2 3.7 0.73 10.2 0.3 3.8 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH62405.1 - 0.049 13.5 0.0 0.42 10.5 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCH62405.1 - 0.063 13.0 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62405.1 - 0.11 13.1 0.0 6.6 7.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HH_signal PF01085.13 CCH62405.1 - 0.13 11.7 1.5 0.28 10.7 0.1 2.1 2 1 0 2 2 2 0 Hedgehog amino-terminal signalling domain TPR_8 PF13181.1 CCH62405.1 - 0.33 10.8 9.2 0.41 10.5 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Na_H_Exchanger PF00999.16 CCH62406.1 - 1e-74 251.3 25.8 1.2e-74 251.1 17.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 CCH62406.1 - 4.1e-70 237.2 55.8 1.5e-67 228.7 38.7 2.4 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus YrhC PF14143.1 CCH62406.1 - 0.17 11.8 0.2 0.54 10.2 0.1 1.8 1 0 0 1 1 1 0 YrhC-like protein Methyltransf_16 PF10294.4 CCH62407.1 - 4.9e-09 35.8 3.0 6.9e-07 28.8 0.2 2.3 2 0 0 2 2 2 2 Putative methyltransferase Semialdhyde_dhC PF02774.13 CCH62408.1 - 1.2e-43 149.0 0.0 1.6e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CCH62408.1 - 4.7e-32 110.8 0.0 8.4e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCH62408.1 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 CCH62408.1 - 0.038 14.5 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ENTH PF01417.15 CCH62409.1 - 2.4e-23 82.3 0.5 4.2e-23 81.5 0.4 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCH62409.1 - 0.031 12.9 0.0 2.7 6.6 0.0 2.3 2 0 0 2 2 2 0 ANTH domain SPAM PF02090.10 CCH62409.1 - 0.16 11.9 5.7 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein zf-CCCH PF00642.19 CCH62410.1 - 5.4e-20 70.5 15.2 3.4e-10 39.3 2.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCH62410.1 - 5e-05 23.1 8.9 0.024 14.6 0.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type DUF1973 PF09315.6 CCH62410.1 - 0.058 12.8 1.3 0.066 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1973) Mcp5_PH PF12814.2 CCH62411.1 - 9.3e-38 128.9 1.1 2.2e-37 127.7 0.0 2.3 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology SAP PF02037.22 CCH62411.1 - 2.2e-07 30.2 0.0 3.6 7.2 0.0 11.9 15 0 0 15 15 15 1 SAP domain Mto2_bdg PF12808.2 CCH62411.1 - 0.12 12.4 6.9 3 8.0 0.0 3.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Homeobox PF00046.24 CCH62411.1 - 0.8 9.3 9.6 6.7 6.4 0.0 6.3 6 0 0 6 6 6 0 Homeobox domain Tropomyosin PF00261.15 CCH62411.1 - 6.4 5.7 69.0 0.1 11.7 3.0 7.5 3 2 2 6 6 6 0 Tropomyosin 2-oxoacid_dh PF00198.18 CCH62412.1 - 6.2e-76 254.6 0.5 8.2e-76 254.2 0.0 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCH62412.1 - 8.3e-16 57.3 1.2 1.4e-15 56.6 0.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme GCV_H PF01597.14 CCH62412.1 - 0.00032 20.3 0.3 0.00072 19.2 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 CCH62412.1 - 0.0086 16.3 0.4 0.044 14.1 0.2 2.2 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CCH62412.1 - 0.028 14.0 0.2 0.15 11.7 0.1 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like DUF2118 PF09891.4 CCH62412.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2360 PF10152.4 CCH62412.1 - 0.36 11.0 4.7 0.62 10.3 3.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAP PF07174.6 CCH62412.1 - 2.9 7.1 19.7 4.7 6.4 13.7 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) zf-C2H2 PF00096.21 CCH62413.1 - 5.3e-09 35.9 15.4 0.0044 17.2 1.9 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62413.1 - 0.00055 20.0 13.7 0.18 12.2 0.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62413.1 - 0.00071 19.7 19.7 0.0033 17.6 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger double domain Bunya_G2 PF03563.8 CCH62413.1 - 0.019 13.8 0.6 0.028 13.3 0.4 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-C2H2_6 PF13912.1 CCH62413.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCH62413.1 - 5.9 7.1 6.9 29 4.9 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zip PF02535.17 CCH62414.1 - 7.2e-64 215.7 5.9 8.7e-64 215.5 4.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF974 PF06159.8 CCH62414.1 - 0.12 11.7 0.4 0.19 11.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF974) TFIID_20kDa PF03847.8 CCH62415.1 - 1.5e-25 89.2 2.6 5.2e-25 87.5 1.8 2.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CCH62415.1 - 0.0043 17.1 0.1 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH62415.1 - 0.0056 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4593 PF15263.1 CCH62415.1 - 0.044 13.6 0.2 0.079 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) Pantoate_ligase PF02569.10 CCH62415.1 - 0.088 11.5 3.0 0.074 11.8 0.4 1.8 1 1 1 2 2 2 0 Pantoate-beta-alanine ligase HTH_45 PF14947.1 CCH62415.1 - 7.9 6.3 8.6 0.72 9.7 0.2 3.2 4 0 0 4 4 4 0 Winged helix-turn-helix Asp PF00026.18 CCH62416.1 - 2.9e-68 230.4 16.8 9.7e-58 195.8 5.1 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH62416.1 - 9.4e-06 25.6 9.2 0.0025 17.8 0.1 3.1 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal RVP PF00077.15 CCH62416.1 - 0.033 14.1 3.0 5.8 6.9 0.0 3.5 3 0 0 3 3 3 0 Retroviral aspartyl protease Mod_r PF07200.8 CCH62417.1 - 3.3e-15 56.3 18.4 5.4e-15 55.6 12.8 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Enkurin PF13864.1 CCH62417.1 - 0.47 10.7 12.0 0.45 10.7 4.0 2.5 1 1 1 2 2 2 0 Calmodulin-binding DUF3635 PF12330.3 CCH62417.1 - 2 8.5 8.0 1.2 9.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3635) ubiquitin PF00240.18 CCH62418.1 - 6.6e-16 57.4 0.6 7.8e-16 57.2 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCH62418.1 - 5.5e-10 38.7 0.4 6.1e-10 38.6 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCH62418.1 - 0.095 12.9 0.1 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Rgp1 PF08737.5 CCH62419.1 - 4.7e-72 243.3 12.7 4.7e-72 243.3 8.8 1.9 2 0 0 2 2 2 1 Rgp1 Pkinase PF00069.20 CCH62420.1 - 6.2e-71 238.5 0.8 3.2e-70 236.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62420.1 - 1.5e-31 109.4 0.4 4.8e-31 107.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCH62420.1 - 0.0012 18.6 8.8 0.002 17.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Herpes_TAF50 PF03326.8 CCH62420.1 - 0.052 12.4 23.0 0.081 11.8 15.9 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) TATR PF03430.8 CCH62420.1 - 0.081 11.5 11.0 0.12 11.0 7.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Ribosomal_60s PF00428.14 CCH62420.1 - 0.16 12.4 3.4 0.42 11.0 2.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 CCH62420.1 - 0.4 8.8 39.1 0.53 8.4 27.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CCH62420.1 - 1.1 8.7 20.4 1.8 8.1 14.2 1.3 1 0 0 1 1 1 0 IncA protein DUF3373 PF11853.3 CCH62420.1 - 2.6 6.4 18.4 3.9 5.9 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PepSY_2 PF13670.1 CCH62420.1 - 5.3 7.0 9.3 12 5.9 6.5 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Flocculin_t3 PF13928.1 CCH62421.1 - 4.8e-09 36.2 13.0 4.8e-09 36.2 9.0 2.9 3 0 0 3 3 3 2 Flocculin type 3 repeat Redoxin PF08534.5 CCH62422.1 - 8.8e-31 106.4 0.1 1e-30 106.1 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCH62422.1 - 2.4e-10 40.1 0.0 3.1e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Colicin-DNase PF12639.2 CCH62423.1 - 0.12 12.6 1.6 0.32 11.2 0.8 2.0 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Herpes_UL55 PF04537.7 CCH62424.1 - 0.03 13.6 0.1 0.039 13.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL55 protein CH PF00307.26 CCH62425.1 - 5.6e-75 248.3 0.2 5.4e-22 77.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CCH62425.1 - 1.2e-06 28.0 0.0 0.46 10.1 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 CCH62425.1 - 1.6e-06 28.1 0.2 4.1e-05 23.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CCH62425.1 - 0.0062 15.7 0.1 7.2 6.1 0.0 3.6 3 0 0 3 3 3 1 EF hand HOOK PF05622.7 CCH62425.1 - 0.048 11.4 0.0 0.21 9.3 0.0 1.9 2 0 0 2 2 2 0 HOOK protein LMBR1 PF04791.11 CCH62426.1 - 0.01 14.4 2.8 0.011 14.2 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein EURL PF06937.6 CCH62426.1 - 0.015 14.7 1.1 0.018 14.4 0.7 1.3 1 0 0 1 1 1 0 EURL protein Trypan_PARP PF05887.6 CCH62426.1 - 0.08 12.7 1.2 0.094 12.5 0.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PBP_sp32 PF07222.7 CCH62426.1 - 0.26 10.4 4.4 0.38 9.9 3.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_I6 PF04595.8 CCH62426.1 - 0.29 9.8 2.1 0.38 9.4 1.4 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family DUF3334 PF11813.3 CCH62426.1 - 0.5 9.8 3.2 0.63 9.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF3682 PF12446.3 CCH62426.1 - 1.2 9.3 9.7 1.8 8.8 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Sporozoite_P67 PF05642.6 CCH62426.1 - 1.4 6.7 8.0 1.7 6.4 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDHD PF02862.12 CCH62426.1 - 4.2 7.1 7.9 5.2 6.8 5.5 1.1 1 0 0 1 1 1 0 DDHD domain CobT PF06213.7 CCH62426.1 - 6.4 5.8 14.2 7.3 5.6 9.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 CCH62426.1 - 8.8 5.4 9.9 11 5.1 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein Abhydrolase_6 PF12697.2 CCH62427.1 - 2.4e-18 66.8 0.0 3.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH62427.1 - 1.7e-15 57.2 0.0 4.2e-15 55.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCH62427.1 - 6e-11 42.2 0.0 4.2e-10 39.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCH62427.1 - 1.8e-05 24.5 0.0 8.7e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase DUF915 PF06028.6 CCH62427.1 - 5.8e-05 22.3 2.7 0.0092 15.1 0.3 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 CCH62427.1 - 0.00011 20.8 0.0 0.0022 16.5 0.0 2.1 2 0 0 2 2 2 1 Ndr family Esterase PF00756.15 CCH62427.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 CCH62427.1 - 0.0042 16.3 0.1 1.1 8.4 0.0 3.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Thioesterase PF00975.15 CCH62427.1 - 0.0093 16.2 0.0 0.47 10.6 0.0 2.8 3 0 0 3 3 3 1 Thioesterase domain DUF676 PF05057.9 CCH62427.1 - 0.0094 15.2 1.2 0.54 9.5 0.0 2.8 3 0 0 3 3 3 1 Putative serine esterase (DUF676) DUF2305 PF10230.4 CCH62427.1 - 0.016 14.6 0.0 0.25 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CCH62427.1 - 0.021 14.4 0.0 0.044 13.3 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.6 CCH62427.1 - 0.035 13.8 0.0 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 CCH62427.1 - 0.036 13.6 0.0 0.57 9.7 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CCH62427.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase F-box-like PF12937.2 CCH62428.1 - 6e-06 25.8 0.2 9.9e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 F-box-like MIT PF04212.13 CCH62428.1 - 0.00034 20.4 0.3 0.001 18.8 0.1 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain F-box PF00646.28 CCH62428.1 - 0.003 17.1 0.4 0.0058 16.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 CCH62428.1 - 0.0051 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CCH62428.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62428.1 - 0.067 13.1 0.0 0.29 11.1 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Nyv1_N PF09426.5 CCH62429.1 - 4.3e-45 152.7 1.6 8.4e-45 151.8 1.1 1.4 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 CCH62429.1 - 3.4e-25 87.4 5.3 3.4e-25 87.4 3.7 1.9 1 1 1 2 2 2 1 Synaptobrevin EMP24_GP25L PF01105.19 CCH62429.1 - 0.022 14.4 7.3 0.22 11.1 5.0 2.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Ribonuc_red_2_N PF08471.5 CCH62429.1 - 0.024 14.7 0.1 0.099 12.7 0.0 1.9 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase Longin PF13774.1 CCH62429.1 - 0.026 14.0 0.4 0.089 12.3 0.0 2.0 2 1 0 2 2 2 0 Regulated-SNARE-like domain ADIP PF11559.3 CCH62429.1 - 0.027 14.3 9.0 0.042 13.7 6.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding L27_1 PF09058.5 CCH62429.1 - 0.061 13.2 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 L27_1 PrmA PF06325.8 CCH62429.1 - 0.074 12.1 2.3 0.12 11.4 1.6 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4413 PF14372.1 CCH62429.1 - 0.17 11.8 3.7 10 6.1 1.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4413) CBFD_NFYB_HMF PF00808.18 CCH62430.1 - 4.6e-05 23.3 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PBP1_TM PF14812.1 CCH62430.1 - 2.1 8.7 11.0 5.3 7.4 6.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRM PF02005.11 CCH62431.1 - 3.1e-140 467.3 0.0 4e-140 467.0 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CCH62431.1 - 6.7e-05 22.5 0.1 0.00014 21.5 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 CCH62431.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EMP70 PF02990.11 CCH62432.1 - 3.2e-202 672.6 15.6 4.3e-202 672.1 10.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Actin PF00022.14 CCH62433.1 - 8.6e-54 182.4 0.0 2.1e-53 181.1 0.0 1.6 1 1 0 1 1 1 1 Actin Opy2 PF09463.5 CCH62434.1 - 6.9e-09 35.6 18.3 1.1e-08 35.0 12.7 1.3 1 0 0 1 1 1 1 Opy2 protein Nucleoplasmin PF03066.10 CCH62434.1 - 0.002 17.6 0.3 0.002 17.6 0.2 2.4 2 0 0 2 2 2 1 Nucleoplasmin PLAC8 PF04749.12 CCH62434.1 - 0.0021 18.5 0.4 0.004 17.6 0.3 1.4 1 0 0 1 1 1 1 PLAC8 family Syndecan PF01034.15 CCH62434.1 - 0.03 13.9 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 Syndecan domain YajC PF02699.10 CCH62434.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit DUF912 PF06024.7 CCH62434.1 - 0.72 9.9 0.0 0.72 9.9 0.0 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zn_Tnp_IS1595 PF12760.2 CCH62434.1 - 1.8 8.4 6.4 3.6 7.4 4.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Transketolase_N PF00456.16 CCH62435.1 - 1.1e-149 497.7 0.0 1.7e-149 497.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCH62435.1 - 5.9e-43 146.4 0.0 9.6e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCH62435.1 - 2.6e-11 43.5 0.0 5.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Not3 PF04065.10 CCH62436.1 - 1.1e-38 132.7 13.2 1.1e-38 132.7 9.2 4.5 3 2 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCH62436.1 - 3.1e-24 85.3 9.7 3.1e-24 85.3 6.7 4.4 2 1 2 4 4 4 2 NOT2 / NOT3 / NOT5 family Ndc1_Nup PF09531.5 CCH62436.1 - 0.32 9.3 33.0 0.021 13.2 10.0 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup AMP-binding PF00501.23 CCH62437.1 - 2.3e-74 250.2 0.0 3e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCH62437.1 - 3.9e-68 229.0 0.0 7.3e-68 228.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CCH62437.1 - 3.4e-15 56.0 0.0 8.6e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CCH62437.1 - 1.7e-11 44.0 0.0 3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CCH62437.1 - 9.4e-06 26.4 0.0 4.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CCH62437.1 - 0.00029 19.6 0.1 0.0015 17.2 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SNF2_N PF00176.18 CCH62438.1 - 2.1e-72 243.4 0.3 3.1e-72 242.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH62438.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CCH62438.1 - 5.8e-09 35.4 9.6 5.8e-09 35.4 6.7 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CCH62438.1 - 8.3e-07 28.6 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 CCH62438.1 - 8.7e-06 25.4 8.7 8.7e-06 25.4 6.0 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH62438.1 - 3e-05 23.9 8.6 3e-05 23.9 5.9 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH62438.1 - 0.00058 19.6 9.7 0.00058 19.6 6.7 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CCH62438.1 - 0.0012 18.4 6.3 0.0012 18.4 4.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH62438.1 - 0.008 15.8 9.0 0.008 15.8 6.3 2.3 2 0 0 2 2 1 1 zinc-RING finger domain Shugoshin_C PF07557.6 CCH62438.1 - 0.016 14.6 0.4 0.045 13.2 0.3 1.9 1 0 0 1 1 1 0 Shugoshin C terminus zf-RING_6 PF14835.1 CCH62438.1 - 0.41 10.4 3.2 1.2 8.9 2.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCH62438.1 - 5 6.9 9.9 0.35 10.6 3.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger TPR_11 PF13414.1 CCH62439.1 - 1.2e-60 201.0 32.7 2.2e-13 49.6 0.0 6.7 2 2 7 9 9 9 9 TPR repeat TPR_1 PF00515.23 CCH62439.1 - 6e-48 158.5 17.7 6.7e-07 28.6 0.0 11.2 12 1 0 12 12 12 8 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62439.1 - 5.4e-46 150.8 8.5 8e-05 22.2 0.0 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62439.1 - 2.4e-36 120.7 9.1 0.0016 18.1 0.0 9.9 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 CCH62439.1 - 2.6e-32 110.6 15.3 1.7e-09 37.4 0.0 7.1 4 3 3 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCH62439.1 - 9.6e-31 103.4 28.4 8.3e-05 22.4 0.0 12.2 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62439.1 - 1.7e-26 90.2 2.5 0.00089 19.6 0.1 9.5 4 2 6 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCH62439.1 - 2.1e-25 88.7 0.1 7.1e-06 26.5 0.0 6.5 4 1 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCH62439.1 - 2.7e-23 82.0 0.8 2.8e-05 24.3 0.2 5.6 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 CCH62439.1 - 5.8e-18 63.2 13.9 0.0022 17.6 0.1 9.4 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 CCH62439.1 - 1.9e-17 62.4 5.2 1.1 9.8 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 CCH62439.1 - 7.1e-12 45.0 3.6 0.0045 16.8 0.8 5.2 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.1 CCH62439.1 - 3.5e-11 42.7 3.8 0.0011 18.1 0.0 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CCH62439.1 - 2.5e-09 37.1 15.9 0.00072 19.6 0.1 5.5 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 CCH62439.1 - 1.9e-05 24.6 5.4 0.25 11.2 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 CCH62439.1 - 0.00012 21.0 2.5 0.63 8.7 0.0 3.7 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 CCH62439.1 - 0.0013 18.5 0.5 1.3 8.9 0.1 3.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 CCH62439.1 - 0.0015 18.3 10.0 0.39 10.7 0.1 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.3 CCH62439.1 - 0.0026 16.6 0.7 3.1 6.4 0.0 3.3 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 RPN7 PF10602.4 CCH62439.1 - 0.0049 16.2 3.5 7 5.9 0.0 4.3 3 2 1 5 5 4 0 26S proteasome subunit RPN7 TPR_20 PF14561.1 CCH62439.1 - 0.011 15.8 0.0 3 8.0 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 CCH62439.1 - 0.032 14.5 0.4 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Med1 PF10744.4 CCH62440.1 - 4.7e-51 173.7 67.0 8.5e-50 169.6 39.8 3.6 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Spermine_synth PF01564.12 CCH62441.1 - 4.2e-101 337.0 0.0 4.9e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase DUF226 PF02890.9 CCH62441.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Methyltransf_31 PF13847.1 CCH62441.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCH62441.1 - 0.037 14.6 0.0 0.061 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_trans_1_4 PF13692.1 CCH62442.1 - 2.4e-15 56.8 0.0 6.6e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CCH62442.1 - 1.1e-13 50.9 0.0 1.9e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCH62442.1 - 3.4e-07 30.5 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 CCH62442.1 - 0.00084 19.5 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.27 CCH62443.1 - 1.7e-29 98.8 7.2 3e-09 35.4 0.0 4.3 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCH62443.1 - 2.8e-28 97.8 3.5 1.1e-15 57.4 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCH62443.1 - 1.5e-26 89.7 3.3 1.8e-08 33.5 0.0 4.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CCH62443.1 - 2e-22 78.5 8.2 4.2e-11 42.2 0.0 4.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCH62443.1 - 1.7e-16 58.7 4.9 1.3e-08 33.7 0.0 4.5 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 CCH62443.1 - 4.6e-13 48.8 0.0 1.9e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCH62443.1 - 6e-08 32.7 0.1 0.0016 18.4 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CCH62443.1 - 1.6e-06 27.7 0.9 1.5e-05 24.6 0.1 2.1 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 CCH62443.1 - 1.7e-06 27.5 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CCH62443.1 - 0.0042 17.0 0.4 0.0081 16.1 0.0 1.7 2 0 0 2 2 1 1 Ca2+ insensitive EF hand Caleosin PF05042.8 CCH62443.1 - 0.0062 16.1 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein DUF892 PF05974.7 CCH62443.1 - 0.015 15.0 0.2 3.3 7.4 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF892) Toprim PF01751.17 CCH62443.1 - 0.044 13.7 0.0 0.34 10.9 0.0 2.1 1 1 1 2 2 2 0 Toprim domain UvrD_C PF13361.1 CCH62443.1 - 0.058 12.8 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Glycos_trans_3N PF02885.12 CCH62443.1 - 0.1 12.1 1.5 1.5 8.5 0.0 3.2 4 1 0 4 4 4 0 Glycosyl transferase family, helical bundle domain Fe-S_biosyn PF01521.15 CCH62445.1 - 4e-11 42.8 0.1 2.3e-07 30.7 0.0 2.3 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis ThiF PF00899.16 CCH62446.1 - 1.8e-24 86.1 1.7 8.2e-24 83.9 1.2 2.0 1 1 0 1 1 1 1 ThiF family UBACT PF02134.16 CCH62446.1 - 2.7e-11 42.8 0.2 1.7e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCH62446.1 - 1.3e-06 27.6 1.2 3.7e-06 26.2 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Peptidase_S48 PF03574.10 CCH62446.1 - 0.12 12.3 0.0 0.76 9.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase family S48 Pho88 PF10032.4 CCH62447.1 - 1.5e-72 242.8 0.5 1.7e-72 242.6 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Septin PF00735.13 CCH62448.1 - 2.1e-107 358.3 8.6 2.1e-107 358.3 2.4 2.6 1 1 1 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCH62448.1 - 2.4e-07 30.7 0.0 5.6e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCH62448.1 - 2.1e-05 23.7 0.7 8.3e-05 21.8 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 CCH62448.1 - 4.1e-05 23.1 0.0 0.00012 21.5 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 CCH62448.1 - 4.5e-05 23.9 0.3 0.0002 21.8 0.0 2.2 2 1 1 3 3 2 1 Miro-like protein Dynamin_N PF00350.18 CCH62448.1 - 0.00044 20.1 5.2 0.2 11.4 0.0 3.4 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 CCH62448.1 - 0.0012 18.0 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 CCH62448.1 - 0.0012 18.9 0.0 0.0073 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CCH62448.1 - 0.0019 17.6 0.1 0.072 12.5 0.0 2.8 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 CCH62448.1 - 0.0035 16.2 0.1 0.0079 15.0 0.1 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 CCH62448.1 - 0.0036 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain RNA_helicase PF00910.17 CCH62448.1 - 0.0076 16.4 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CCH62448.1 - 0.018 14.8 0.0 0.056 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCH62448.1 - 0.021 14.7 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCH62448.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 CCH62448.1 - 0.032 13.6 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Ras family MobB PF03205.9 CCH62448.1 - 0.083 12.5 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 CCH62448.1 - 0.13 11.7 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 CCH62448.1 - 0.47 10.7 5.0 0.14 12.4 0.4 2.3 2 1 0 2 2 2 0 ABC transporter SIS PF01380.17 CCH62449.1 - 6.3e-59 197.2 0.0 9.6e-30 102.8 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCH62449.1 - 2.7e-27 95.4 0.2 2.5e-19 69.2 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCH62449.1 - 3.7e-16 59.2 0.0 8.1e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCH62449.1 - 1.3e-09 37.8 0.0 2.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCH62449.1 - 9.4e-09 34.3 0.1 1.6e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CCH62449.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 SIS domain Pyr_redox_2 PF07992.9 CCH62450.1 - 3.7e-28 98.7 0.0 4.9e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCH62450.1 - 6.7e-18 64.8 0.1 2.6e-15 56.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH62450.1 - 1.7e-07 31.4 0.0 0.00014 21.9 0.0 2.6 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCH62450.1 - 3.2e-06 26.2 0.7 0.47 9.2 0.1 4.2 4 1 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CCH62450.1 - 0.00031 20.9 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCH62450.1 - 0.0007 19.6 0.0 0.75 9.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CCH62450.1 - 0.00093 19.1 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCH62450.1 - 0.0025 16.9 0.2 0.018 14.1 0.0 2.2 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 CCH62450.1 - 0.0035 16.3 0.0 1.3 7.9 0.0 3.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CCH62450.1 - 0.0074 15.2 0.0 1.9 7.2 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCH62450.1 - 0.0082 15.0 1.4 0.82 8.4 0.2 2.6 3 1 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.14 CCH62450.1 - 0.059 12.4 0.0 4.8 6.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 CCH62450.1 - 0.076 12.7 0.1 8.7 6.0 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PQ-loop PF04193.9 CCH62451.1 - 5e-33 112.4 1.6 9e-16 57.1 0.4 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CCH62451.1 - 0.012 15.4 3.3 0.76 9.6 2.8 2.8 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Pkinase PF00069.20 CCH62453.1 - 7.3e-67 225.2 0.2 7.3e-67 225.2 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62453.1 - 8.9e-47 159.3 0.0 2.5e-46 157.8 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH62453.1 - 1.8e-06 27.1 0.0 4.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like ATP-synt_S1 PF05827.7 CCH62454.1 - 1.6e-46 158.8 2.1 1.9e-46 158.6 1.5 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF843 PF05814.6 CCH62454.1 - 0.15 11.8 6.7 0.19 11.5 1.7 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) ATP-synt_8 PF00895.15 CCH62454.1 - 6.5 7.0 8.7 0.96 9.7 1.9 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 Asp PF00026.18 CCH62455.1 - 1.9e-22 79.9 0.0 1.4e-20 73.8 0.0 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCH62455.1 - 0.004 17.1 0.1 0.01 15.7 0.1 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF3992 PF13157.1 CCH62455.1 - 0.99 9.6 4.4 6.3 7.0 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3992) Sec23_trunk PF04811.10 CCH62456.1 - 4.1e-57 193.3 0.0 8.6e-57 192.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCH62456.1 - 1.7e-21 75.5 0.5 5e-21 74.0 0.3 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CCH62456.1 - 3.7e-13 48.8 2.8 7.7e-13 47.7 2.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCH62456.1 - 4.4e-08 33.5 0.0 1.3e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCH62456.1 - 1.2e-06 28.1 0.0 2.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat EntA_Immun PF08951.5 CCH62456.1 - 0.023 14.8 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Enterocin A Immunity Pal1 PF08316.6 CCH62457.1 - 6.2e-50 169.2 1.7 6.2e-50 169.2 1.2 4.2 3 2 3 6 6 6 1 Pal1 cell morphology protein Sod_Fe_C PF02777.13 CCH62458.1 - 1.2e-11 44.4 2.4 1.3e-05 24.9 0.1 2.7 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Svf1 PF08622.5 CCH62459.1 - 3.7e-128 427.0 8.3 4.4e-128 426.8 5.8 1.0 1 0 0 1 1 1 1 Svf1-like Laps PF10169.4 CCH62459.1 - 0.07 13.3 0.7 0.21 11.7 0.5 1.8 1 0 0 1 1 1 0 Learning-associated protein DUF3612 PF12268.3 CCH62459.1 - 0.085 12.6 0.0 6.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3612) Nop14 PF04147.7 CCH62459.1 - 3.1 5.6 13.2 4.4 5.0 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family tRNA-synt_1d PF00750.14 CCH62460.1 - 1.1e-102 343.5 4.9 1.3e-102 343.2 3.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCH62460.1 - 1.1e-28 99.6 0.0 2.7e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CCH62460.1 - 9.5e-10 38.8 0.0 5.1e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Cpn60_TCP1 PF00118.19 CCH62461.1 - 5.8e-145 483.6 15.3 6.6e-145 483.4 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bac_DnaA PF00308.13 CCH62461.1 - 0.041 13.5 0.7 0.46 10.1 0.1 2.6 2 1 1 3 3 3 0 Bacterial dnaA protein Fcf1 PF04900.7 CCH62462.1 - 1.6e-36 124.3 0.8 2.2e-36 124.0 0.0 1.6 2 0 0 2 2 2 1 Fcf1 ING PF12998.2 CCH62463.1 - 1.9e-13 50.6 5.7 1.9e-13 50.6 4.0 2.3 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCH62463.1 - 1.7e-09 37.2 8.0 1.7e-09 37.2 5.5 1.9 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 CCH62463.1 - 0.013 15.5 1.5 0.049 13.7 0.2 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF2360 PF10152.4 CCH62463.1 - 0.032 14.5 7.9 0.054 13.7 5.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MatE PF01554.13 CCH62464.1 - 1.2e-60 203.7 27.4 6.2e-35 120.2 6.3 3.4 4 0 0 4 4 4 2 MatE DUF818 PF05677.7 CCH62464.1 - 0.077 11.7 1.2 0.12 11.0 0.8 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Brix PF04427.13 CCH62465.1 - 2.5e-40 138.1 3.8 4.5e-40 137.3 2.6 1.4 1 0 0 1 1 1 1 Brix domain RRM_1 PF00076.17 CCH62466.1 - 2.9e-40 135.7 0.1 1.9e-15 56.1 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH62466.1 - 6.3e-24 83.7 0.0 6.3e-08 32.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH62466.1 - 1.3e-19 69.7 0.2 4.3e-10 39.2 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCH62466.1 - 0.00044 20.0 5.6 0.00061 19.6 0.1 3.3 3 1 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCH62466.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif STE PF02200.11 CCH62467.1 - 4.5e-55 184.5 3.2 4.5e-55 184.5 2.2 1.9 2 0 0 2 2 2 1 STE like transcription factor ResIII PF04851.10 CCH62468.1 - 2e-26 92.9 0.0 2e-26 92.9 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCH62468.1 - 4.8e-16 58.7 0.0 1.9e-15 56.7 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH62468.1 - 3.6e-12 45.9 1.3 7.5e-12 44.9 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CCH62468.1 - 0.0001 21.4 2.8 0.00032 19.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCH62468.1 - 0.0037 17.4 0.1 0.029 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCH62468.1 - 5.5 6.4 10.2 0.71 9.4 0.0 3.1 2 2 1 3 3 3 0 AAA domain Pkinase PF00069.20 CCH62469.1 - 1.7e-48 165.0 1.4 2.7e-43 147.9 0.6 2.9 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62469.1 - 1.6e-23 83.1 0.2 9.6e-23 80.5 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH62469.1 - 0.0037 16.2 0.0 0.0072 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Peptidase_C13 PF01650.13 CCH62470.1 - 8e-45 153.1 0.3 8e-45 153.1 0.2 1.8 2 0 0 2 2 2 1 Peptidase C13 family Thioredoxin_7 PF13899.1 CCH62471.1 - 3.9e-18 65.2 0.0 8.8e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 CCH62471.1 - 5.1e-13 48.8 0.1 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCH62471.1 - 9.3e-13 47.4 0.3 3.6e-12 45.6 0.2 2.0 2 0 0 2 2 2 1 UBA-like domain C2-set PF05790.10 CCH62471.1 - 0.0063 16.4 0.1 0.017 15.1 0.1 1.7 1 1 0 1 1 1 1 Immunoglobulin C2-set domain Peroxin-3 PF04882.7 CCH62472.1 - 7.1e-51 173.2 38.4 5.2e-40 137.4 22.7 3.4 1 1 1 2 2 2 2 Peroxin-3 SID-1_RNA_chan PF13965.1 CCH62472.1 - 3 5.8 17.9 0.0063 14.7 2.9 2.2 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 Secretin_N_2 PF07655.8 CCH62472.1 - 3.3 8.1 20.2 2.9 8.3 9.0 3.2 3 0 0 3 3 3 0 Secretin N-terminal domain Skp1 PF01466.14 CCH62473.1 - 9e-37 124.9 0.3 1.4e-36 124.3 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCH62473.1 - 1.7e-11 44.0 0.0 3.7e-10 39.7 0.0 2.3 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain GRAM PF02893.15 CCH62474.1 - 2.1e-16 59.1 0.1 5.2e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Cnd3 PF12719.2 CCH62475.1 - 9.9e-92 307.1 9.5 2.4e-91 305.8 4.8 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 CCH62475.1 - 2.3e-08 33.4 1.5 0.15 12.1 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CCH62475.1 - 1.3e-05 25.3 0.0 0.001 19.3 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Cohesin_HEAT PF12765.2 CCH62475.1 - 7.9e-05 22.5 0.4 0.89 9.5 0.0 3.5 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 CCH62475.1 - 0.19 12.2 0.4 2.2 8.9 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat ABA_GPCR PF12430.3 CCH62476.1 - 6.3e-53 178.8 5.7 6.3e-53 178.8 3.9 2.7 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CCH62476.1 - 2.7e-16 59.3 0.5 7.4e-16 57.9 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) FYVE PF01363.16 CCH62477.1 - 3.4e-18 65.3 30.2 1.8e-14 53.3 4.5 3.6 3 1 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 CCH62477.1 - 0.017 14.6 0.4 0.048 13.2 0.3 1.8 1 0 0 1 1 1 0 Rabenosyn Rab binding domain zf-C2H2_4 PF13894.1 CCH62477.1 - 0.092 13.1 0.1 0.092 13.1 0.1 5.1 5 1 1 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH62477.1 - 0.099 13.0 0.2 0.099 13.0 0.1 4.9 5 2 1 6 6 6 0 Zinc finger, C2H2 type zf-met2 PF12907.2 CCH62477.1 - 0.45 10.5 0.1 0.45 10.5 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding SpoIIE PF07228.7 CCH62478.1 - 4.3e-28 98.3 0.0 5.9e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CCH62478.1 - 2.4e-07 30.4 0.2 0.0096 15.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCH62478.1 - 0.0041 16.5 0.0 0.014 14.7 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C O-ag_pol_Wzy PF14296.1 CCH62478.1 - 0.18 10.3 4.7 0.33 9.4 3.2 1.4 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy HisG_C PF08029.6 CCH62479.1 - 0.026 14.4 0.3 6 6.8 0.1 2.6 1 1 1 2 2 2 0 HisG, C-terminal domain Peptidase_M1 PF01433.15 CCH62480.1 - 4.6e-117 391.4 12.5 8.9e-116 387.1 6.3 2.9 2 1 0 2 2 2 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CCH62480.1 - 1.5e-15 57.3 0.2 3.1e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily SPA PF08616.5 CCH62480.1 - 0.0096 15.6 2.1 0.016 14.9 0.1 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis CN_hydrolase PF00795.17 CCH62481.1 - 1.2e-24 86.6 0.0 2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CCH62481.1 - 1.4e-22 79.7 0.0 3.9e-22 78.3 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CCH62481.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Nop10p PF04135.7 CCH62482.1 - 1.1e-22 79.4 0.5 1.3e-22 79.2 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ubiq-assoc PF09145.5 CCH62483.1 - 2.9e-17 62.2 1.0 6.9e-17 61.0 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-associated TPR_11 PF13414.1 CCH62483.1 - 1.4e-08 34.2 0.1 5.8e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CCH62483.1 - 8.3e-06 25.6 0.0 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62483.1 - 0.00029 20.5 0.6 1.3 9.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCH62483.1 - 0.00095 18.6 5.7 1.9 8.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.26 CCH62483.1 - 0.0032 17.1 0.1 0.0096 15.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain CENP-O PF09496.5 CCH62484.1 - 1.3e-18 67.0 1.9 4.1e-18 65.3 0.1 2.4 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Tht1 PF04163.7 CCH62484.1 - 0.00025 19.5 8.1 0.00025 19.5 5.6 1.9 2 0 0 2 2 2 1 Tht1-like nuclear fusion protein NIF PF03031.13 CCH62485.1 - 9.8e-50 168.3 0.3 9.8e-50 168.3 0.2 2.2 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase WD40 PF00400.27 CCH62486.1 - 2.8e-35 118.9 0.7 3.2e-09 36.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 CCH62486.1 - 4.4e-30 103.5 16.6 1.2e-29 102.0 11.5 1.8 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 CCH62486.1 - 0.00017 21.3 0.9 0.45 10.3 0.0 3.8 3 1 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region Abhydro_lipase PF04083.11 CCH62487.1 - 2.1e-12 46.2 0.0 4.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCH62487.1 - 9.5e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH62487.1 - 0.00073 19.3 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH62487.1 - 0.0022 17.5 0.0 0.005 16.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF900 PF05990.7 CCH62487.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) FSH1 PF03959.8 CCH62487.1 - 0.035 13.5 0.3 0.67 9.3 0.1 2.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Corona_nucleoca PF00937.13 CCH62487.1 - 0.34 9.8 10.9 0.47 9.3 7.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1509 PF07420.6 CCH62487.1 - 0.66 9.1 11.3 1 8.5 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) PUF PF00806.14 CCH62488.1 - 8e-59 191.9 20.6 1.1e-07 30.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.7 CCH62489.1 - 1.1e-17 63.9 4.5 1.3e-17 63.6 3.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.9 CCH62490.1 - 3.3e-69 232.3 2.0 3.3e-69 232.3 1.4 2.2 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CCH62490.1 - 1.8e-21 75.4 0.5 7.2e-21 73.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 CCH62490.1 - 0.0016 18.7 0.0 0.046 14.0 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats DUF2870 PF11069.3 CCH62491.1 - 0.012 15.6 4.2 0.012 15.6 2.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Podoplanin PF05808.6 CCH62491.1 - 0.14 11.7 8.3 0.039 13.4 3.4 1.8 2 0 0 2 2 2 0 Podoplanin LicD PF04991.8 CCH62491.1 - 1.1 9.2 8.3 1.6 8.7 5.7 1.3 1 0 0 1 1 1 0 LicD family Sigma54_AID PF00309.15 CCH62491.1 - 4.3 6.8 6.5 0.4 10.1 1.1 1.8 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) MIP PF00230.15 CCH62492.1 - 2.4e-36 125.3 9.7 3e-36 125.0 6.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein OAD_gamma PF04277.8 CCH62492.1 - 1.1 9.6 3.5 1.7 9.0 1.9 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain tRNA-synt_1b PF00579.20 CCH62494.1 - 2.9e-77 259.6 0.0 4e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 CCH62496.1 - 1.5e-16 59.8 16.1 1.5e-16 59.8 11.2 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CCH62496.1 - 9.5e-06 25.2 0.0 2.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 CCH62496.1 - 0.00048 19.8 1.0 0.00048 19.8 0.7 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCH62496.1 - 0.0072 16.3 1.7 0.0072 16.3 1.2 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UPF0118 PF01594.11 CCH62496.1 - 0.42 9.5 0.8 0.98 8.3 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF20 zf-Tim10_DDP PF02953.10 CCH62497.1 - 2.5e-14 52.3 2.3 3.6e-14 51.7 1.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Clat_adaptor_s PF01217.15 CCH62498.1 - 1.8e-55 186.5 3.5 2.1e-55 186.3 2.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SE PF08491.5 CCH62499.1 - 2e-110 368.0 0.2 2.6e-110 367.6 0.1 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CCH62499.1 - 4.5e-12 45.7 0.0 7.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCH62499.1 - 5.9e-06 25.4 0.0 1.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCH62499.1 - 0.0005 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 CCH62499.1 - 0.0019 17.8 0.2 0.0031 17.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 CCH62499.1 - 0.003 16.6 0.1 0.0057 15.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 CCH62499.1 - 0.0033 16.3 0.3 0.0077 15.1 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CCH62499.1 - 0.013 15.9 0.1 0.035 14.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCH62499.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCH62499.1 - 0.026 13.4 0.1 0.24 10.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 CCH62499.1 - 0.038 12.4 1.0 0.12 10.8 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein GDI PF00996.13 CCH62499.1 - 0.069 11.4 0.2 0.16 10.2 0.0 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor ApbA PF02558.11 CCH62499.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CCH62499.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 CCH62499.1 - 0.19 10.7 0.2 0.4 9.7 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase LsmAD PF06741.8 CCH62500.1 - 5.1e-29 100.1 0.4 5.1e-29 100.1 0.3 2.5 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 CCH62500.1 - 4.8e-14 52.0 0.1 3e-13 49.4 0.1 2.5 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CCH62500.1 - 0.00027 20.6 0.2 0.0013 18.4 0.1 2.3 1 0 0 1 1 1 1 Scd6-like Sm domain Ribonuc_red_sm PF00268.16 CCH62502.1 - 6.3e-115 383.0 2.5 8.3e-115 382.6 1.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF3595 PF12166.3 CCH62502.1 - 1.9 7.2 7.3 7 5.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3595) Ribonuc_red_sm PF00268.16 CCH62503.1 - 7.6e-66 221.9 10.6 9e-66 221.7 7.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain tRNA-synt_1g PF09334.6 CCH62504.1 - 6.1e-102 341.1 2.5 2.2e-101 339.3 1.7 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCH62504.1 - 1.3e-19 69.7 0.9 1.4e-12 46.4 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCH62504.1 - 3.5e-06 26.3 1.1 0.0012 18.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 CCH62504.1 - 0.00053 18.7 0.0 0.00094 17.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) Hira PF07569.6 CCH62504.1 - 0.091 11.9 0.3 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split DNA_pol_E_B PF04042.11 CCH62505.1 - 5.2e-42 143.4 0.1 9.6e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.2 CCH62505.1 - 0.043 13.6 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PS_Dcarbxylase PF02666.10 CCH62506.1 - 2.1e-52 177.3 0.0 4e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CCH62506.1 - 2.1e-12 46.6 0.2 6.1e-08 32.4 0.1 3.0 2 0 0 2 2 2 2 C2 domain APG6 PF04111.7 CCH62507.1 - 0.99 8.3 13.1 1.1 8.1 9.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_X-T_C PF08411.5 CCH62507.1 - 1.7 7.6 6.4 2 7.3 4.5 1.1 1 0 0 1 1 1 0 Exonuclease C-terminal DUF4544 PF15077.1 CCH62507.1 - 1.8 8.0 8.1 2.1 7.8 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF3602 PF12223.3 CCH62507.1 - 3.2 8.1 9.1 46 4.4 6.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) GBP_C PF02841.9 CCH62507.1 - 6 5.9 15.6 6.7 5.8 10.8 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RapA_C PF12137.3 CCH62507.1 - 6.2 5.5 8.6 6.7 5.4 6.0 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal NARP1 PF12569.3 CCH62507.1 - 6.6 5.3 15.8 8.3 5.0 11.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Band_7 PF01145.20 CCH62508.1 - 5.2e-22 78.6 0.5 9.4e-22 77.7 0.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Spo12 PF05032.7 CCH62509.1 - 6.1e-17 60.9 0.7 6.1e-17 60.9 0.5 2.3 3 0 0 3 3 3 1 Spo12 family SMI1_KNR4 PF09346.5 CCH62510.1 - 1.7e-36 125.0 0.4 4.7e-36 123.6 0.0 2.0 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 CCH62510.1 - 0.54 10.7 0.0 0.54 10.7 0.0 4.1 3 1 2 5 5 5 0 SMI1-KNR4 cell-wall GAGA_bind PF06217.7 CCH62510.1 - 3.6 7.4 8.6 7 6.5 6.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Lectin_C PF00059.16 CCH62511.1 - 0.021 15.4 0.1 0.43 11.2 0.1 2.7 2 0 0 2 2 2 0 Lectin C-type domain Pex24p PF06398.6 CCH62512.1 - 4e-23 81.7 9.6 5.8e-23 81.2 6.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_S4 PF00163.14 CCH62513.1 - 1.1e-23 83.4 1.1 1.7e-23 82.8 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCH62513.1 - 2.2e-12 46.1 0.0 4.9e-12 45.0 0.0 1.6 2 0 0 2 2 2 1 S4 domain Ion_trans PF00520.26 CCH62514.1 - 8.4e-83 276.5 119.6 1.1e-32 112.8 4.9 5.8 6 0 0 6 6 6 4 Ion transport protein PKD_channel PF08016.7 CCH62514.1 - 0.0014 17.1 7.4 0.0014 17.1 5.2 7.0 6 1 1 7 7 7 4 Polycystin cation channel Gpi1 PF05024.10 CCH62515.1 - 6.9e-53 179.1 19.3 1.6e-52 177.9 13.4 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MRP-S33 PF08293.6 CCH62516.1 - 2.4e-26 91.4 0.4 3e-26 91.1 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribosomal_S2 PF00318.15 CCH62517.1 - 9.8e-40 136.0 0.0 2.3e-36 125.0 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 zf-ZPR1 PF03367.8 CCH62518.1 - 2.3e-117 387.7 11.9 5.9e-59 197.8 0.2 2.6 3 0 0 3 3 3 2 ZPR1 zinc-finger domain RNHCP PF12647.2 CCH62518.1 - 0.061 13.1 1.4 1.6 8.6 0.3 2.8 2 0 0 2 2 2 0 RNHCP domain DUF2294 PF10057.4 CCH62518.1 - 0.077 12.6 1.2 0.16 11.6 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) OrfB_Zn_ribbon PF07282.6 CCH62518.1 - 0.82 9.3 5.3 8 6.2 0.0 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 CCH62518.1 - 1.6 8.5 13.1 1.8 8.3 0.1 3.7 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 CCH62518.1 - 2.7 7.8 7.3 0.25 11.1 0.5 2.6 3 0 0 3 3 3 0 zinc-ribbons zf-ribbon_3 PF13248.1 CCH62518.1 - 6.6 6.0 13.9 3 7.1 0.1 3.5 3 1 1 4 4 4 0 zinc-ribbon domain ETF PF01012.16 CCH62519.1 - 2.4e-22 79.4 0.0 3e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain UPF0242 PF06785.6 CCH62519.1 - 0.11 11.2 0.4 0.17 10.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) LSM PF01423.17 CCH62520.1 - 1.2e-05 24.7 0.2 2.2e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 LSM domain 4HBT_3 PF13622.1 CCH62521.1 - 3.9e-20 72.6 0.0 4.9e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 CCH62521.1 - 4.4e-20 71.6 0.1 2.8e-15 56.1 0.0 3.1 2 1 1 3 3 3 3 Acyl-CoA thioesterase ILVD_EDD PF00920.16 CCH62522.1 - 7.9e-202 671.2 0.0 9.1e-202 671.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.27 CCH62523.1 - 7.4e-58 190.5 32.9 4.2e-09 35.9 0.1 12.7 13 0 0 13 13 13 10 WD domain, G-beta repeat DUF3533 PF12051.3 CCH62525.1 - 7.9e-116 386.9 18.6 1.2e-115 386.3 12.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) SUI1 PF01253.17 CCH62526.1 - 5.2e-19 67.8 2.1 9.9e-19 66.9 1.5 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF4093 PF13331.1 CCH62526.1 - 0.33 11.1 3.4 0.57 10.4 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) RNase_PH PF01138.16 CCH62527.1 - 3.5e-30 105.0 0.0 6e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCH62527.1 - 7.7e-08 32.1 0.2 1.9e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gp_dh_C PF02800.15 CCH62529.1 - 2.2e-73 244.9 0.1 3.7e-73 244.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCH62529.1 - 1.2e-57 194.0 0.2 2.2e-57 193.2 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CCH62529.1 - 0.0036 17.2 1.0 0.0071 16.2 0.2 2.1 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DJ-1_PfpI PF01965.19 CCH62530.1 - 2.4e-19 69.2 0.0 3.4e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CCH62530.1 - 0.047 13.2 0.4 0.27 10.7 0.1 2.4 2 1 0 2 2 2 0 N-terminal domain of DJ-1_PfpI family DJ-1_PfpI PF01965.19 CCH62531.1 - 2.6e-21 75.6 0.0 4.7e-21 74.7 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 CCH62531.1 - 0.013 15.0 0.1 0.035 13.6 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family RNA_pol_Rpb4 PF03874.11 CCH62532.1 - 3.6e-28 97.9 9.0 8.2e-28 96.7 6.2 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 TraH PF06122.6 CCH62532.1 - 0.06 12.1 0.1 0.059 12.1 0.1 1.1 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein Cpn60_TCP1 PF00118.19 CCH62533.1 - 5.5e-150 500.1 3.2 6.3e-150 500.0 2.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sad1_UNC PF07738.8 CCH62535.1 - 1.6e-06 27.9 0.5 0.014 15.1 0.0 3.2 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.7 CCH62535.1 - 2.7 7.8 7.0 3.2 7.5 2.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 CCH62535.1 - 3 8.1 8.0 1.8 8.8 1.4 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2457 PF10446.4 CCH62536.1 - 0.0087 14.8 25.0 0.014 14.2 17.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF3445 PF11927.3 CCH62536.1 - 0.013 14.8 0.5 0.013 14.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3445) DUF3637 PF12337.3 CCH62536.1 - 0.04 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) Daxx PF03344.10 CCH62536.1 - 0.35 9.3 25.9 0.49 8.8 17.9 1.1 1 0 0 1 1 1 0 Daxx Family Acetyltransf_11 PF13720.1 CCH62536.1 - 3.9 7.7 10.1 6.2 7.1 0.3 2.8 2 1 1 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Tom37_C PF11801.3 CCH62537.1 - 4.2e-33 114.5 2.4 6.4e-33 113.9 1.7 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CCH62537.1 - 5.5e-19 68.2 0.0 1.8e-18 66.5 0.0 1.9 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Hepatitis_core PF00906.15 CCH62537.1 - 0.086 12.4 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Hepatitis core antigen DUF4448 PF14610.1 CCH62538.1 - 4.3e-49 166.5 0.0 5.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mcm10 PF09332.6 CCH62539.1 - 0.086 12.1 3.9 0.11 11.7 2.7 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF2457 PF10446.4 CCH62539.1 - 8.2 5.0 12.0 11 4.5 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TrmE_N PF10396.4 CCH62540.1 - 1.6e-31 108.6 0.0 3.6e-31 107.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CCH62540.1 - 3.5e-22 78.5 2.8 3.5e-22 78.5 1.9 2.6 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCH62540.1 - 4.7e-12 45.7 3.3 1.9e-10 40.4 0.4 2.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTPase_Cys_C PF12631.2 CCH62540.1 - 2e-10 40.9 0.1 5.8e-10 39.4 0.1 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CCH62540.1 - 7.6e-10 38.2 4.0 1.8e-09 37.0 2.8 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCH62540.1 - 4.7e-08 33.5 4.9 3.7e-07 30.6 0.2 3.3 2 2 1 3 3 3 1 Miro-like protein Ras PF00071.17 CCH62540.1 - 3.7e-07 29.6 0.3 0.023 14.1 0.0 2.6 2 0 0 2 2 2 2 Ras family Dynamin_N PF00350.18 CCH62540.1 - 3.2e-05 23.8 0.2 3.2e-05 23.8 0.1 3.7 2 2 2 4 4 4 1 Dynamin family DUF258 PF03193.11 CCH62540.1 - 0.00037 19.7 0.2 0.0011 18.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CCH62540.1 - 0.005 16.3 4.5 1.5 8.2 0.0 3.4 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CCH62540.1 - 0.027 14.6 2.7 1.2 9.2 0.0 3.5 2 1 0 3 3 3 0 AAA domain Arf PF00025.16 CCH62540.1 - 0.051 12.8 7.5 0.22 10.7 0.1 3.4 3 1 1 4 4 4 0 ADP-ribosylation factor family AAA_17 PF13207.1 CCH62540.1 - 1.3 9.9 5.0 2.8 8.7 0.5 3.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCH62540.1 - 9.9 6.4 12.3 2.5 8.4 1.3 3.6 2 1 1 3 3 3 0 AAA domain BLOC1_2 PF10046.4 CCH62541.1 - 0.0024 17.9 11.2 0.0066 16.5 7.7 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ACCA PF03255.9 CCH62541.1 - 0.004 16.7 1.8 0.0052 16.3 1.3 1.3 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Baculo_FP PF03258.9 CCH62541.1 - 0.015 14.3 5.7 0.017 14.2 4.0 1.2 1 0 0 1 1 1 0 Baculovirus FP protein DUF2250 PF10007.4 CCH62541.1 - 0.016 15.0 0.9 0.023 14.5 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) TMP_2 PF06791.8 CCH62541.1 - 0.033 13.7 0.7 0.046 13.3 0.5 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DNA_pol3_theta PF06440.6 CCH62541.1 - 0.045 13.3 0.1 0.066 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit BLYB PF05289.6 CCH62541.1 - 0.078 12.7 4.8 0.23 11.3 3.3 1.6 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein ATPgrasp_Ter PF15632.1 CCH62541.1 - 0.087 11.5 0.2 0.092 11.4 0.2 1.2 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Rogdi_lz PF10259.4 CCH62541.1 - 0.15 11.1 3.9 0.11 11.5 0.5 1.8 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein V_ATPase_I PF01496.14 CCH62541.1 - 0.37 8.5 4.8 0.38 8.5 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EB1 PF03271.12 CCH62541.1 - 0.41 10.7 2.9 11 6.1 0.1 2.5 2 1 0 2 2 2 0 EB1-like C-terminal motif Colicin-DNase PF12639.2 CCH62541.1 - 0.41 10.9 1.8 0.93 9.7 1.2 1.7 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Allexi_40kDa PF05549.6 CCH62541.1 - 0.5 9.6 5.3 0.59 9.3 3.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF848 PF05852.6 CCH62541.1 - 0.63 9.8 7.8 1.1 9.1 3.8 1.9 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CorA PF01544.13 CCH62541.1 - 1.8 7.4 6.1 2.9 6.8 4.2 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_hydro_76 PF03663.9 CCH62542.1 - 5.3e-151 503.2 24.7 7e-151 502.8 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 CCH62543.1 - 1.3e-150 501.9 25.5 1.8e-150 501.4 17.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 CCH62544.1 - 3.5e-151 503.7 26.7 4.6e-151 503.3 18.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UQ_con PF00179.21 CCH62545.1 - 2e-48 163.4 0.0 2.2e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCH62545.1 - 0.054 13.3 0.8 0.071 13.0 0.5 1.6 1 1 0 1 1 1 0 RWD domain Tht1 PF04163.7 CCH62546.1 - 5.1e-37 127.4 32.9 3.9e-36 124.5 22.6 2.0 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein FliD_C PF07195.7 CCH62546.1 - 0.0022 17.3 16.7 0.0052 16.1 2.8 2.4 2 1 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus ApoLp-III PF07464.6 CCH62546.1 - 0.0058 16.6 2.0 0.083 12.9 0.6 2.7 3 0 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.13 CCH62546.1 - 0.15 11.5 2.2 0.75 9.2 1.5 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain EIF_2_alpha PF07541.7 CCH62546.1 - 0.27 10.9 2.1 0.79 9.4 0.4 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Salp15 PF12115.3 CCH62546.1 - 0.37 11.0 3.7 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF4164 PF13747.1 CCH62546.1 - 1.4 9.1 5.1 1.8 8.7 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Snapin_Pallidin PF14712.1 CCH62546.1 - 4 7.8 10.7 19 5.6 1.7 3.6 3 0 0 3 3 3 0 Snapin/Pallidin Sec7 PF01369.15 CCH62547.1 - 0.0026 17.4 2.6 0.014 15.0 0.1 2.3 2 0 0 2 2 2 2 Sec7 domain DNA_primase_lrg PF04104.9 CCH62548.1 - 3.2e-72 242.9 0.0 5.9e-72 242.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit p450 PF00067.17 CCH62549.1 - 6.7e-56 189.7 0.2 8.5e-56 189.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 CENP-F_N PF10481.4 CCH62550.1 - 0.043 13.1 1.8 0.087 12.1 1.2 1.5 1 0 0 1 1 1 0 Cenp-F N-terminal domain EST1 PF10374.4 CCH62550.1 - 0.074 13.0 3.8 0.27 11.2 1.7 2.3 1 1 1 2 2 2 0 Telomerase activating protein Est1 Pex2_Pex12 PF04757.9 CCH62551.1 - 6e-41 140.3 15.2 7.2e-41 140.0 10.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CCH62551.1 - 4.3e-05 23.4 10.3 7.2e-05 22.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCH62551.1 - 4.7e-05 22.9 7.1 7.3e-05 22.3 4.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH62551.1 - 0.012 15.4 11.1 0.021 14.6 7.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCH62551.1 - 0.22 11.2 9.5 0.38 10.4 6.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 CCH62551.1 - 1 8.8 3.5 5.2 6.6 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif F_bP_aldolase PF01116.15 CCH62552.1 - 4.7e-93 311.4 0.1 5.3e-93 311.2 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DWNN PF08783.6 CCH62553.1 - 9.6e-32 108.7 1.7 5.1e-31 106.4 0.0 2.4 2 0 0 2 2 2 1 DWNN domain zf-Nse PF11789.3 CCH62553.1 - 1.6e-06 27.5 1.0 4e-06 26.2 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CCH62553.1 - 4.9e-06 26.4 0.2 1.3e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.18 CCH62553.1 - 0.0013 18.6 2.7 0.0027 17.5 1.9 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CCH62553.1 - 0.0026 17.2 3.3 0.0026 17.2 2.3 1.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCH62553.1 - 0.067 12.9 0.2 0.19 11.5 0.1 1.8 1 0 0 1 1 1 0 Zinc knuckle Rubredoxin PF00301.15 CCH62553.1 - 0.069 13.0 1.8 3.5 7.5 0.1 3.3 3 0 0 3 3 3 0 Rubredoxin zf-CCHC_5 PF14787.1 CCH62553.1 - 0.076 12.5 0.4 0.076 12.5 0.3 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger TF_Zn_Ribbon PF08271.7 CCH62553.1 - 0.18 11.1 3.3 0.39 10.0 0.1 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding Mito_fiss_reg PF05308.6 CCH62553.1 - 5.8 6.1 10.8 14 4.9 4.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator TFIIA_gamma_C PF02751.9 CCH62554.1 - 1.6e-25 88.6 0.3 2.2e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CCH62554.1 - 9.7e-23 79.5 0.1 1.3e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Striatin PF08232.7 CCH62556.1 - 4.6e-24 85.2 1.3 4.6e-24 85.2 0.9 4.6 3 1 0 3 3 3 1 Striatin family DUF4239 PF14023.1 CCH62556.1 - 0.18 11.1 0.0 0.18 11.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF4557 PF15101.1 CCH62556.1 - 0.23 11.2 14.9 0.51 10.1 10.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TMEM51 PF15345.1 CCH62556.1 - 2.6 7.6 17.0 7.5 6.1 8.9 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 TCTP PF00838.12 CCH62557.1 - 1.5e-70 236.4 1.0 1.7e-70 236.3 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein CUE PF02845.11 CCH62558.1 - 1.6e-05 24.2 0.0 3.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.7 CCH62559.1 - 7.7e-29 99.3 5.0 9e-29 99.1 3.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 CCH62559.1 - 0.0042 16.9 3.8 0.6 10.0 0.2 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 CCH62559.1 - 0.0071 16.0 5.1 0.84 9.4 0.2 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CCH62559.1 - 0.13 12.2 3.1 0.43 10.6 2.2 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.4 CCH62559.1 - 0.26 11.3 4.3 4.2 7.4 3.0 2.1 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DASH_Ask1 PF08655.5 CCH62560.1 - 3.4e-24 84.4 0.2 6.2e-24 83.6 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 GLE1 PF07817.8 CCH62560.1 - 0.025 13.5 0.6 0.041 12.8 0.1 1.7 2 0 0 2 2 2 0 GLE1-like protein Frag1 PF10277.4 CCH62561.1 - 4.7e-72 241.9 22.0 5.6e-72 241.7 15.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family FCH PF00611.18 CCH62563.1 - 2e-07 31.1 0.2 2e-07 31.1 0.2 3.0 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 CCH62563.1 - 0.00032 20.1 0.0 0.00062 19.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCH62563.1 - 0.0045 16.3 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH62563.1 - 0.0061 16.1 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Actin PF00022.14 CCH62564.1 - 3.1e-22 78.5 0.4 8.2e-21 73.8 0.1 2.6 2 1 0 2 2 2 1 Actin MreB_Mbl PF06723.8 CCH62564.1 - 0.018 13.6 0.0 6 5.3 0.0 2.9 3 0 0 3 3 3 0 MreB/Mbl protein Peptidase_S24 PF00717.18 CCH62565.1 - 0.00024 20.6 0.2 0.0011 18.5 0.1 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCH62565.1 - 0.0026 17.2 0.0 0.055 13.0 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Rhodanese PF00581.15 CCH62566.1 - 5.6e-10 39.5 0.0 1.4e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain DUF1257 PF06868.6 CCH62566.1 - 0.058 13.2 0.3 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) zf-C2H2 PF00096.21 CCH62567.1 - 4.1e-12 45.6 12.4 3.1e-06 27.2 2.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62567.1 - 7.2e-10 38.4 10.4 2.8e-05 24.1 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62567.1 - 1.2e-07 31.6 17.5 2.5e-06 27.4 0.9 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCH62567.1 - 3.4e-06 27.0 8.9 0.0046 17.0 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCH62567.1 - 8.9e-06 25.7 6.4 0.02 15.0 1.1 3.0 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCH62567.1 - 2.5e-05 23.9 7.2 0.0033 17.2 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 CCH62567.1 - 0.024 14.4 15.3 0.051 13.3 0.5 3.6 3 0 0 3 3 3 0 BED zinc finger GAGA PF09237.6 CCH62567.1 - 0.075 12.6 3.9 2.2 7.9 0.1 3.2 2 1 1 3 3 3 0 GAGA factor Dynamin_M PF01031.15 CCH62569.1 - 1.5e-107 358.7 0.0 3e-107 357.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCH62569.1 - 1.1e-54 184.7 0.4 2.4e-54 183.6 0.3 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CCH62569.1 - 5.2e-29 99.9 3.4 1.7e-28 98.3 2.4 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCH62569.1 - 0.00038 20.4 0.3 0.0044 16.9 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCH62569.1 - 0.0014 19.0 0.6 0.029 14.8 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein PIP5K PF01504.13 CCH62569.1 - 0.0061 15.7 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Podoplanin PF05808.6 CCH62570.1 - 0.01 15.4 2.3 0.013 15.0 1.6 1.1 1 0 0 1 1 1 0 Podoplanin KAT11 PF08214.6 CCH62571.1 - 9e-93 311.0 1.5 1.1e-92 310.7 1.1 1.0 1 0 0 1 1 1 1 Histone acetylation protein Sfi1 PF08457.5 CCH62572.1 - 2.6e-12 45.9 27.3 2.6e-12 45.9 18.9 3.9 1 1 3 4 4 4 2 Sfi1 spindle body protein Sfi1_C PF10638.4 CCH62572.1 - 1.6e-11 44.5 0.9 7.6e-11 42.3 0.6 2.2 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Nsp1_C PF05064.8 CCH62573.1 - 1.5e-37 127.8 5.8 1.5e-37 127.8 4.0 2.2 1 1 1 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 CCH62573.1 - 1.2e-14 54.5 281.7 1.6e-07 31.5 25.0 9.1 1 1 7 8 8 8 5 Nucleoporin FG repeat region Muted PF14942.1 CCH62573.1 - 0.1 12.4 0.8 0.21 11.4 0.4 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF87 PF01935.12 CCH62573.1 - 0.14 12.0 8.8 0.34 10.6 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF87 CENP-F_leu_zip PF10473.4 CCH62573.1 - 0.8 9.5 7.1 15 5.4 5.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHIPPO-rpt PF07004.7 CCH62573.1 - 1.5 9.8 46.2 18 6.4 0.3 11.5 5 2 1 6 6 6 0 Sperm-tail PG-rich repeat GCS PF03074.11 CCH62574.1 - 7e-143 476.1 0.1 9.6e-143 475.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GTP_EFTU PF00009.22 CCH62575.1 - 1.9e-55 187.2 0.0 4.5e-55 186.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCH62575.1 - 1.1e-23 82.8 0.0 3.1e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCH62575.1 - 2.2e-18 65.9 0.3 3.8e-10 39.4 0.0 3.0 3 0 0 3 3 3 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCH62575.1 - 4.4e-06 26.7 0.2 1.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH62575.1 - 0.00014 21.7 0.1 0.00041 20.2 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCH62575.1 - 0.03 13.5 0.0 0.091 11.9 0.0 1.9 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AHS1 PF02682.11 CCH62575.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 MobB PF03205.9 CCH62575.1 - 0.11 12.1 0.2 5.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B zf-C2HC5 PF06221.8 CCH62576.1 - 1.6e-20 72.6 6.2 3e-20 71.7 4.3 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SET PF00856.23 CCH62578.1 - 0.0032 17.7 4.3 0.038 14.3 0.1 2.9 2 0 0 2 2 2 1 SET domain PHD PF00628.24 CCH62578.1 - 3.1 7.5 19.2 0.088 12.5 7.9 2.4 2 1 0 2 2 2 0 PHD-finger Pkinase PF00069.20 CCH62579.1 - 8.4e-55 185.7 0.6 8.4e-55 185.7 0.4 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62579.1 - 9.3e-29 100.2 1.4 1.4e-26 93.1 0.3 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase DUF2201_N PF13203.1 CCH62579.1 - 0.11 11.6 5.4 0.22 10.6 3.7 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain BP28CT PF08146.7 CCH62580.1 - 1.2e-39 135.4 2.7 1.2e-39 135.4 1.9 4.0 5 0 0 5 5 5 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CCH62580.1 - 3.8e-16 59.1 0.5 3.8e-16 59.1 0.3 4.9 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 CCH62580.1 - 0.028 14.7 0.0 23 5.3 0.0 4.7 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.1 CCH62580.1 - 0.21 12.1 1.6 2.8 8.5 0.1 3.5 3 0 0 3 3 3 0 HEAT-like repeat UNC-50 PF05216.8 CCH62581.1 - 3e-88 294.9 20.6 3.4e-88 294.7 14.3 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.17 CCH62582.1 - 4.7e-16 57.9 2.1 4.6e-08 32.5 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CCH62582.1 - 2.4e-08 33.7 0.0 1.8e-07 30.9 0.0 3.9 3 1 0 3 3 3 2 PLD-like domain PX PF00787.19 CCH62582.1 - 0.0001 22.0 9.9 0.00041 20.1 0.3 4.7 5 0 0 5 5 5 2 PX domain GATA PF00320.22 CCH62584.1 - 5.7e-14 51.1 3.0 5.7e-14 51.1 2.1 1.9 2 0 0 2 2 2 1 GATA zinc finger eIF-5_eIF-2B PF01873.12 CCH62584.1 - 0.12 12.0 0.7 0.19 11.3 0.5 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Nudix_N_2 PF14803.1 CCH62584.1 - 0.58 9.8 2.3 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 Nudix N-terminal SSP160 PF06933.6 CCH62584.1 - 1.9 6.3 15.8 2.4 6.0 10.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Snf7 PF03357.16 CCH62586.1 - 5.3e-15 55.2 21.0 5.3e-15 55.2 14.6 1.3 1 1 0 1 1 1 1 Snf7 PNPase PF03726.9 CCH62586.1 - 0.14 12.4 7.8 0.056 13.7 1.3 2.4 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DltD_M PF04918.7 CCH62586.1 - 1.3 9.1 13.8 1.3 9.1 8.1 1.9 1 1 1 2 2 2 0 DltD central region NAD_binding_5 PF07994.7 CCH62586.1 - 3.9 6.8 9.5 1.1 8.6 2.1 2.1 1 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase DUF3496 PF12001.3 CCH62586.1 - 9.7 6.4 10.6 5.7 7.2 5.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) WD40 PF00400.27 CCH62587.1 - 2.3e-25 87.4 6.5 2.5e-07 30.3 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat DASH_Spc34 PF08657.5 CCH62588.1 - 1e-40 140.0 8.8 1.2e-40 139.8 6.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 eIF-4B PF06273.6 CCH62588.1 - 0.05 12.3 1.9 0.078 11.7 1.3 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PIR PF00399.14 CCH62589.1 - 4.6e-14 51.1 20.6 1.7e-07 30.3 3.7 3.9 3 0 0 3 3 3 3 Yeast PIR protein repeat Mucin PF01456.12 CCH62589.1 - 0.69 9.6 19.4 1.2 8.8 13.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PIR PF00399.14 CCH62591.1 - 4.6e-33 111.4 47.9 1.2e-08 33.9 2.7 4.8 4 0 0 4 4 4 4 Yeast PIR protein repeat DUF973 PF06157.6 CCH62591.1 - 1.4 7.8 5.5 10 4.9 0.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF973) Macoilin PF09726.4 CCH62591.1 - 4 5.5 10.0 4.9 5.3 6.9 1.0 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CCH62591.1 - 5 6.9 12.6 6.5 6.5 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S28 PF10213.4 CCH62592.1 - 1.7e-31 108.9 0.2 2.7e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Ada3 PF10198.4 CCH62593.1 - 2e-39 134.3 5.4 2e-39 134.3 3.8 2.2 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 DUF4632 PF15451.1 CCH62593.1 - 0.22 11.4 3.3 3.1 7.7 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4632) UQ_con PF00179.21 CCH62594.1 - 8.1e-44 148.4 0.0 1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CCH62594.1 - 4.1e-27 93.5 2.2 8.5e-27 92.5 1.5 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CCH62594.1 - 0.00075 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B UBA_2 PF08587.6 CCH62594.1 - 0.037 14.2 0.1 0.077 13.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) PXA PF02194.10 CCH62595.1 - 7e-11 42.0 0.6 2e-10 40.5 0.4 2.0 1 1 0 1 1 1 1 PXA domain PseudoU_synth_2 PF00849.17 CCH62596.1 - 2.2e-17 63.3 0.3 1.4e-15 57.5 0.2 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase Nipped-B_C PF12830.2 CCH62597.1 - 6.3e-40 136.8 2.9 3.7e-39 134.3 0.7 3.0 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CCH62597.1 - 7.8e-13 48.0 0.1 2e-09 37.2 0.6 3.0 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Metallophos PF00149.23 CCH62598.1 - 9.8e-15 54.4 2.9 1.6e-14 53.7 2.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCH62598.1 - 0.0087 15.9 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ubiquitin PF00240.18 CCH62599.1 - 1.5e-34 117.1 0.9 2.7e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CCH62599.1 - 9.5e-25 86.1 2.5 1.7e-24 85.3 1.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CCH62599.1 - 1e-19 69.9 0.7 1e-19 69.9 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCH62599.1 - 8.8e-06 25.8 0.2 3.9e-05 23.8 0.1 2.0 2 1 0 2 2 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCH62599.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCH62599.1 - 0.0013 18.6 0.4 0.0034 17.2 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCH62599.1 - 0.0058 16.7 0.3 0.0084 16.2 0.2 1.4 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CCH62599.1 - 0.05 13.4 0.4 0.1 12.4 0.2 1.6 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain IBR PF01485.16 CCH62599.1 - 0.059 13.2 0.4 0.084 12.7 0.3 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 CCH62599.1 - 0.064 13.2 0.1 0.15 12.1 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 CCH62599.1 - 0.16 10.2 1.7 6 5.0 0.2 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF1410 PF07198.6 CCH62599.1 - 3.9 7.8 5.5 6.2 7.2 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1410) Sec1 PF00995.18 CCH62601.1 - 9.7e-136 453.6 19.5 1.1e-135 453.4 13.6 1.0 1 0 0 1 1 1 1 Sec1 family SIR2 PF02146.12 CCH62602.1 - 7e-30 104.0 0.0 1.5e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Peptidase_C71 PF12386.3 CCH62602.1 - 0.027 13.8 0.4 2.6 7.4 0.0 3.3 3 1 1 4 4 4 0 Pseudomurein endo-isopeptidase Pei ATP_bind_1 PF03029.12 CCH62603.1 - 3e-86 288.8 0.0 3.4e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCH62603.1 - 0.00017 22.3 0.0 0.0004 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CCH62603.1 - 0.00047 19.0 0.1 0.0012 17.6 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 CCH62603.1 - 0.00051 19.5 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 CCH62603.1 - 0.0012 18.7 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CCH62603.1 - 0.0031 17.6 0.0 0.02 15.0 0.0 2.3 2 1 0 2 2 2 1 RNA helicase T2SE PF00437.15 CCH62603.1 - 0.0063 15.4 0.0 0.0097 14.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.9 CCH62603.1 - 0.0071 16.0 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CCH62603.1 - 0.0087 16.3 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.22 CCH62603.1 - 0.01 15.2 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 CCH62603.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CCH62603.1 - 0.012 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCH62603.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CCH62603.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.14 CCH62603.1 - 0.024 14.0 0.0 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCH62603.1 - 0.025 14.4 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCH62603.1 - 0.027 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCH62603.1 - 0.027 13.6 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 CCH62603.1 - 0.034 14.3 0.0 0.086 13.0 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Gtr1_RagA PF04670.7 CCH62603.1 - 0.039 13.0 0.2 0.36 9.9 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF87 PF01935.12 CCH62603.1 - 0.04 13.7 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 CCH62603.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 CCH62603.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCH62603.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin PPV_E1_C PF00519.12 CCH62603.1 - 0.076 11.6 0.0 0.15 10.6 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase FtsK_SpoIIIE PF01580.13 CCH62603.1 - 0.08 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 CCH62603.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family NACHT PF05729.7 CCH62603.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCH62603.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 CCH62603.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCH62603.1 - 0.13 12.0 0.1 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 CCH62603.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CCH62603.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF221 PF02714.10 CCH62604.1 - 2.4e-98 329.0 19.2 2.4e-98 329.0 13.3 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCH62604.1 - 8.6e-39 132.6 1.5 8.6e-39 132.6 1.1 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCH62604.1 - 3.1e-14 53.2 0.5 2.6e-13 50.3 0.3 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) DEAD PF00270.24 CCH62605.1 - 1.1e-37 129.1 0.1 7.3e-37 126.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH62605.1 - 1.5e-21 76.0 0.1 3.8e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 CCH62605.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 CCH62606.1 - 1e-63 213.9 0.0 1.2e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CCH62606.1 - 2.1e-06 28.5 0.1 4.5e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH62606.1 - 0.0011 19.3 0.5 0.0048 17.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCH62606.1 - 0.0026 17.6 0.0 0.011 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 CCH62606.1 - 0.0045 16.8 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_28 PF13521.1 CCH62606.1 - 0.0049 16.8 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 CCH62606.1 - 0.0099 15.4 0.1 0.043 13.3 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Viral_Hsp90 PF03225.9 CCH62606.1 - 0.043 12.1 0.1 0.059 11.6 0.1 1.1 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Cytidylate_kin2 PF13189.1 CCH62606.1 - 0.054 13.3 0.1 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family FHA PF00498.21 CCH62608.1 - 5.1e-16 58.5 0.1 1.6e-15 56.9 0.1 1.9 1 0 0 1 1 1 1 FHA domain DUF4321 PF14209.1 CCH62608.1 - 0.028 14.1 0.5 0.064 12.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4321) DUF3891 PF13030.1 CCH62608.1 - 0.15 11.5 2.3 0.24 10.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) Cation_efflux PF01545.16 CCH62609.1 - 1.6e-55 188.2 5.1 1.6e-55 188.2 3.5 2.5 3 0 0 3 3 3 1 Cation efflux family OppC_N PF12911.2 CCH62609.1 - 0.02 14.2 0.1 0.2 11.0 0.0 2.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C ORC4_C PF14629.1 CCH62609.1 - 0.048 13.0 0.3 0.1 11.9 0.2 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Topoisom_bac PF01131.15 CCH62610.1 - 6.2e-92 308.5 0.0 7.9e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CCH62610.1 - 1.3e-20 73.1 0.0 3.1e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DUF3703 PF12487.3 CCH62610.1 - 0.085 12.5 0.0 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) EST1_DNA_bind PF10373.4 CCH62611.1 - 5.8e-49 166.7 8.6 5.8e-49 166.7 5.9 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCH62611.1 - 2.1e-25 89.2 3.7 2.1e-25 89.2 2.6 4.4 3 1 0 3 3 3 2 Telomerase activating protein Est1 PIP5K PF01504.13 CCH62612.1 - 7e-79 264.4 2.3 7e-79 264.4 1.6 2.3 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase W2 PF02020.13 CCH62613.1 - 9.6e-16 57.5 5.5 9.6e-16 57.5 3.8 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CCH62613.1 - 4e-11 41.8 23.2 0.0012 18.2 5.0 4.6 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CCH62613.1 - 1.7e-08 34.0 0.0 3.7e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCH62613.1 - 0.0073 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CCH62613.1 - 0.75 9.4 23.4 0.44 10.1 3.8 3.6 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Ras PF00071.17 CCH62614.1 - 6.3e-51 171.9 0.0 7.4e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH62614.1 - 1.2e-14 54.8 0.0 1.7e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH62614.1 - 6.6e-08 31.9 0.0 8.4e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Anp1 PF03452.9 CCH62615.1 - 1.2e-109 365.6 0.1 1.5e-109 365.2 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CCH62615.1 - 0.0081 15.8 0.2 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Alk_phosphatase PF00245.15 CCH62616.1 - 7.8e-125 416.8 0.0 9.4e-125 416.5 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CCH62616.1 - 5.3e-06 26.0 0.1 1.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Metalloenzyme superfamily cwf21 PF08312.7 CCH62617.1 - 5e-10 39.0 1.5 5e-10 39.0 1.1 1.7 2 0 0 2 2 2 1 cwf21 domain MRP-S28 PF10213.4 CCH62617.1 - 0.18 11.8 7.4 0.23 11.5 5.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein THOC7 PF05615.8 CCH62617.1 - 1.9 8.7 13.1 25 5.1 9.2 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 Glyco_transf_15 PF01793.11 CCH62618.1 - 4e-97 325.1 4.2 5.2e-97 324.7 2.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mg296 PF09644.5 CCH62618.1 - 0.072 12.9 0.4 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Mg296 protein TPR_11 PF13414.1 CCH62619.1 - 1.5e-16 59.7 1.3 2.1e-13 49.7 0.7 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCH62619.1 - 2.1e-15 55.5 3.1 4.5e-05 22.8 0.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62619.1 - 8.1e-10 37.8 1.2 0.025 14.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62619.1 - 0.00021 20.8 5.5 0.91 9.4 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH62619.1 - 0.00059 19.7 0.4 1.3 8.9 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CCH62619.1 - 0.00069 19.7 3.5 0.0068 16.5 2.0 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CCH62619.1 - 0.0028 17.5 1.2 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat INCENP_ARK-bind PF03941.10 CCH62620.1 - 6.5e-11 41.9 1.1 6.5e-11 41.9 0.7 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Methyltransf_19 PF04672.7 CCH62620.1 - 0.062 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl methyltransferase F-box PF00646.28 CCH62622.1 - 0.00032 20.2 0.1 0.0012 18.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCH62622.1 - 0.0012 18.5 0.6 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 CCH62622.1 - 0.021 14.4 0.8 0.021 14.4 0.5 6.6 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) BESS PF02944.15 CCH62622.1 - 0.05 13.1 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 BESS motif LRR_6 PF13516.1 CCH62622.1 - 0.079 13.0 0.1 0.079 13.0 0.1 7.9 9 0 0 9 9 9 0 Leucine Rich repeat LRR_1 PF00560.28 CCH62622.1 - 0.83 9.9 0.1 0.83 9.9 0.0 7.8 7 3 0 7 7 7 0 Leucine Rich Repeat Lge1 PF11488.3 CCH62623.1 - 1.3e-14 54.1 0.4 2.7e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.20 CCH62624.1 - 2.1e-18 66.7 0.0 2.9e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCH62624.1 - 6.5e-08 32.6 0.0 9.8e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCH62624.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCH62624.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding T_Ag_DNA_bind PF02217.11 CCH62624.1 - 0.039 14.3 0.4 0.97 9.8 0.0 2.8 3 0 0 3 3 3 0 Origin of replication binding protein Pkinase PF00069.20 CCH62625.1 - 2.4e-73 246.4 0.0 2.7e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62625.1 - 5.1e-33 114.2 0.0 6.4e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH62625.1 - 6.2e-06 25.3 0.0 1.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH62625.1 - 0.011 15.4 0.2 0.069 12.8 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCH62625.1 - 0.018 14.0 0.1 0.063 12.3 0.1 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CCH62625.1 - 0.51 9.0 3.6 6.8 5.3 0.1 2.1 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Gly_transf_sug PF04488.10 CCH62626.1 - 1.1e-20 73.9 0.3 2.5e-20 72.7 0.2 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif 7TM_GPCR_Srh PF10318.4 CCH62626.1 - 0.0027 16.5 1.4 0.0049 15.7 0.9 1.3 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF3816 PF12822.2 CCH62626.1 - 0.13 12.1 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) TcdA_TcdB PF12919.2 CCH62626.1 - 4.1 5.7 6.9 1 7.7 1.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 CCH62627.1 - 3.2e-102 341.0 1.2 6.5e-102 340.0 0.8 1.5 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCH62627.1 - 1.3e-31 108.5 1.4 1.9e-31 108.0 0.2 1.9 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) ABC2_membrane PF01061.19 CCH62628.1 - 1.3e-68 230.2 45.8 6.4e-37 126.7 7.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCH62628.1 - 6.6e-37 126.8 0.0 2e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCH62628.1 - 1.4e-35 121.0 4.2 5.9e-30 102.9 0.1 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCH62628.1 - 4.8e-11 42.5 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CCH62628.1 - 4.3e-07 29.2 0.0 0.00019 20.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCH62628.1 - 8.7e-06 25.2 0.0 0.022 14.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 CCH62628.1 - 0.00012 21.5 0.5 0.015 14.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 CCH62628.1 - 0.00012 21.5 0.2 0.022 14.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 CCH62628.1 - 0.00025 21.1 0.0 0.043 13.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCH62628.1 - 0.00031 20.4 0.0 0.021 14.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CCH62628.1 - 0.00075 19.5 0.2 0.028 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 CCH62628.1 - 0.0011 18.1 4.6 0.0011 18.1 3.2 3.0 3 0 0 3 3 3 2 ABC-2 family transporter protein UPF0079 PF02367.12 CCH62628.1 - 0.0014 18.2 1.1 0.018 14.6 0.2 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CCH62628.1 - 0.0015 18.4 0.1 1.7 8.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.14 CCH62628.1 - 0.0026 17.0 0.0 4.6 6.4 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCH62628.1 - 0.0028 18.4 0.0 0.084 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCH62628.1 - 0.003 17.8 0.0 0.21 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCH62628.1 - 0.005 16.8 0.0 0.092 12.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CCH62628.1 - 0.0068 15.5 0.0 2.7 7.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CCH62628.1 - 0.0079 15.9 1.6 0.15 11.8 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain RNA_helicase PF00910.17 CCH62628.1 - 0.013 15.6 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 CCH62628.1 - 0.013 15.4 0.1 3.2 7.7 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 CCH62628.1 - 0.015 15.8 0.1 9.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 CCH62628.1 - 0.047 13.1 0.9 4.7 6.5 0.2 2.8 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 CCH62628.1 - 0.051 13.1 0.3 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCH62628.1 - 0.075 12.7 0.2 16 5.1 0.1 3.1 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.1 CCH62628.1 - 0.08 12.8 0.4 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 CCH62628.1 - 0.11 11.9 1.2 1.2 8.5 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CCH62628.1 - 0.14 12.3 0.0 3.1 8.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Exo5 PF09810.4 CCH62629.1 - 1e-25 90.6 1.1 4.3e-16 59.0 0.2 2.3 2 0 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 CCH62629.1 - 5.8e-07 29.1 0.0 1.4e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Glutaredoxin PF00462.19 CCH62631.1 - 9e-18 64.0 0.0 1.4e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin FTR1 PF03239.9 CCH62632.1 - 1.8e-95 319.4 0.0 8.9e-94 313.8 0.0 2.0 1 1 0 1 1 1 1 Iron permease FTR1 family DUF3754 PF12576.3 CCH62632.1 - 2.4 7.7 5.9 0.3 10.7 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) CorA PF01544.13 CCH62633.1 - 3.3e-05 23.0 6.7 3.3e-05 23.0 4.6 2.6 2 2 1 3 3 3 1 CorA-like Mg2+ transporter protein PspB PF06667.7 CCH62633.1 - 0.034 14.0 0.4 0.95 9.4 0.0 2.7 2 0 0 2 2 2 0 Phage shock protein B Glyco_transf_15 PF01793.11 CCH62634.1 - 2.2e-125 417.9 11.3 2.9e-125 417.6 7.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4338 PF14236.1 CCH62634.1 - 0.027 13.1 0.1 0.042 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Abhydrolase_6 PF12697.2 CCH62635.1 - 4.3e-20 72.5 0.0 5.2e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH62635.1 - 2.6e-10 40.2 0.0 4.7e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH62635.1 - 3.7e-10 39.7 0.0 8.3e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 CCH62635.1 - 5.1e-07 29.3 0.0 6.7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CCH62635.1 - 6e-06 26.0 0.0 1.4e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.8 CCH62635.1 - 0.00029 20.4 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF900 PF05990.7 CCH62635.1 - 0.00086 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 CCH62635.1 - 0.0026 16.7 0.0 0.0073 15.3 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.5 CCH62635.1 - 0.015 14.1 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.2 CCH62635.1 - 0.04 12.7 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 CCH62635.1 - 0.12 11.7 0.0 6.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3605 PF12239.3 CCH62637.1 - 1.8e-38 131.9 1.2 2.1e-38 131.6 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) VPS9 PF02204.13 CCH62639.1 - 4.5e-16 58.7 2.6 1.1e-15 57.4 1.8 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF1504 PF07399.6 CCH62640.1 - 0.13 10.8 0.2 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1504) SH3_1 PF00018.23 CCH62641.1 - 1e-17 63.1 0.0 2.3e-09 36.4 0.0 3.3 3 0 0 3 3 3 2 SH3 domain PX PF00787.19 CCH62641.1 - 6.4e-17 61.3 0.0 1.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 CCH62641.1 - 1.6e-10 40.3 0.0 0.00019 20.9 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 CCH62641.1 - 1.6e-08 34.1 0.1 4.5e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.12 CCH62641.1 - 1.3e-07 31.0 0.0 6.3e-06 25.5 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain UCH PF00443.24 CCH62642.1 - 3.4e-39 134.5 1.6 4.7e-39 134.1 1.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH62642.1 - 2.4e-08 33.7 0.9 6.6e-08 32.3 0.6 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase McrBC PF10117.4 CCH62642.1 - 0.025 13.5 0.1 0.056 12.3 0.1 1.6 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component GCR1_C PF12550.3 CCH62643.1 - 0.0022 17.8 0.3 0.032 14.1 0.2 2.5 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes WD40 PF00400.27 CCH62644.1 - 1.2e-58 192.9 19.2 2.5e-12 46.1 0.0 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CCH62644.1 - 5.5e-47 159.4 2.7 1.1e-46 158.5 1.9 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 CCH62644.1 - 1.2e-06 27.9 0.1 3.1e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.11 CCH62644.1 - 0.0029 15.9 0.4 0.26 9.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain PGI PF00342.14 CCH62646.1 - 7.1e-224 743.6 2.0 8.2e-224 743.4 1.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SAP30_Sin3_bdg PF13867.1 CCH62646.1 - 0.019 14.8 0.5 3.1 7.7 0.0 3.2 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.27 CCH62647.1 - 3.2e-22 77.5 11.1 0.0001 22.0 0.0 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCH62647.1 - 2.5e-18 65.7 2.5 8.3e-18 64.0 0.6 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Mt_ATP-synt_B PF05405.9 CCH62648.1 - 1.9e-48 164.0 5.8 2.6e-48 163.5 4.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rabaptin PF03528.10 CCH62648.1 - 0.45 10.4 7.2 0.72 9.7 5.0 1.3 1 0 0 1 1 1 0 Rabaptin RVT_N PF13655.1 CCH62648.1 - 2.6 8.1 6.5 20 5.3 0.1 3.6 3 1 1 4 4 4 0 N-terminal domain of reverse transcriptase DUF3510 PF12022.3 CCH62648.1 - 2.7 8.0 10.4 2.1 8.4 0.6 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Med8 PF10232.4 CCH62649.1 - 9.1e-24 84.2 0.1 1e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 SlyX PF04102.7 CCH62649.1 - 1.3 9.4 3.9 4.8 7.6 0.1 2.4 1 1 1 2 2 2 0 SlyX TarH PF02203.10 CCH62649.1 - 4 7.2 8.3 8.2 6.2 5.8 1.6 1 1 0 1 1 1 0 Tar ligand binding domain homologue DUF4140 PF13600.1 CCH62649.1 - 7.6 7.0 9.1 11 6.5 3.2 2.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3535 PF12054.3 CCH62650.1 - 2.6e-130 434.9 0.8 2.1e-128 428.7 1.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CCH62650.1 - 1.8e-78 263.4 0.0 3.3e-78 262.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH62650.1 - 9.5e-14 51.0 0.0 2.7e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 CCH62650.1 - 1.6e-13 49.4 2.1 0.4 10.8 0.0 8.1 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.2 CCH62650.1 - 8.8e-09 35.6 1.1 0.26 11.6 0.0 6.4 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCH62650.1 - 3.6e-07 30.4 0.4 1 9.9 0.0 7.5 8 0 0 8 8 8 1 HEAT-like repeat DUF1546 PF07571.8 CCH62650.1 - 0.038 14.0 0.1 13 5.9 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) UPF0016 PF01169.14 CCH62652.1 - 2.4e-37 126.8 22.5 1.9e-19 69.6 4.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 AAA PF00004.24 CCH62653.1 - 6.3e-32 110.5 0.0 1.6e-31 109.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCH62653.1 - 6.4e-07 30.2 0.1 3e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCH62653.1 - 8e-07 29.2 0.0 2.6e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH62653.1 - 5.3e-05 23.5 0.4 0.00029 21.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCH62653.1 - 7.9e-05 22.4 0.1 0.031 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCH62653.1 - 0.00029 20.7 0.0 0.0032 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCH62653.1 - 0.0003 20.4 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 CCH62653.1 - 0.00036 20.3 0.2 0.00036 20.3 0.1 2.1 2 1 0 2 2 2 1 Archaeal ATPase AAA_11 PF13086.1 CCH62653.1 - 0.00048 19.7 0.1 0.0084 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCH62653.1 - 0.00082 19.6 0.0 0.0033 17.7 0.0 2.0 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CCH62653.1 - 0.00083 19.3 0.1 0.0031 17.5 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCH62653.1 - 0.0012 18.7 4.0 0.0038 17.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCH62653.1 - 0.0014 18.8 0.2 0.0076 16.4 0.0 2.5 2 1 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 CCH62653.1 - 0.0016 17.5 0.0 0.016 14.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 CCH62653.1 - 0.0022 18.3 2.8 0.0022 18.3 2.0 2.7 2 2 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CCH62653.1 - 0.0035 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCH62653.1 - 0.0042 16.6 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCH62653.1 - 0.0059 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein UPF0079 PF02367.12 CCH62653.1 - 0.0074 15.9 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCH62653.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 CCH62653.1 - 0.032 13.0 0.5 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 CCH62653.1 - 0.038 13.1 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CCH62653.1 - 0.046 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CCH62653.1 - 0.091 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein MobB PF03205.9 CCH62653.1 - 0.11 12.2 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CCH62653.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain BRO1 PF03097.13 CCH62654.1 - 3e-85 286.2 9.1 5.3e-85 285.4 6.3 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCH62654.1 - 8.5e-36 123.4 17.7 2.7e-35 121.7 12.3 1.8 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Flexi_CP_N PF08358.5 CCH62654.1 - 0.87 9.4 6.9 19 5.1 0.1 4.2 4 0 0 4 4 4 0 Carlavirus coat MBA1 PF07961.6 CCH62655.1 - 2.2e-76 255.7 0.7 2.7e-76 255.5 0.5 1.0 1 0 0 1 1 1 1 MBA1-like protein Sec16_C PF12931.2 CCH62656.1 - 6.3e-58 196.7 3.7 6.3e-58 196.7 2.6 2.1 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CCH62656.1 - 1.3e-11 44.4 0.8 9.8e-11 41.6 0.0 3.1 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Ceramidase PF05875.7 CCH62657.1 - 2e-89 299.2 16.1 2.6e-89 298.8 11.1 1.1 1 0 0 1 1 1 1 Ceramidase MFS_1 PF07690.11 CCH62657.1 - 0.0052 15.5 7.7 0.0052 15.5 5.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane_5 PF13346.1 CCH62657.1 - 0.0061 15.8 6.9 0.36 10.1 2.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein DUF2207 PF09972.4 CCH62657.1 - 0.024 13.2 0.8 0.05 12.2 0.5 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF973 PF06157.6 CCH62657.1 - 0.085 11.8 1.5 0.14 11.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3043 PF11241.3 CCH62657.1 - 0.31 10.6 1.0 0.52 9.8 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4181 PF13789.1 CCH62657.1 - 0.47 10.3 9.9 0.083 12.8 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) EamA PF00892.15 CCH62657.1 - 8 6.5 14.6 2.8 7.9 4.8 2.9 2 1 1 3 3 3 0 EamA-like transporter family SRF-TF PF00319.13 CCH62658.1 - 2.6e-23 81.0 0.1 2.6e-23 81.0 0.0 2.7 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3820 PF12843.2 CCH62658.1 - 0.07 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3820) Pyr_redox_2 PF07992.9 CCH62659.1 - 1.3e-37 129.6 0.7 1.8e-37 129.1 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CCH62659.1 - 1.8e-35 121.2 0.0 2.1e-34 117.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CCH62659.1 - 2e-19 69.7 6.0 2.6e-18 66.1 0.7 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH62659.1 - 1.2e-12 48.3 0.4 5e-10 39.7 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCH62659.1 - 2.7e-07 30.0 0.2 1.2e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CCH62659.1 - 5.4e-06 25.5 0.3 0.00053 18.9 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 CCH62659.1 - 7.5e-06 25.6 0.1 0.0043 16.6 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 CCH62659.1 - 3.1e-05 22.6 5.3 0.058 11.8 0.2 3.7 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 CCH62659.1 - 7.5e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CCH62659.1 - 0.0014 17.5 1.9 0.0014 17.5 1.3 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCH62659.1 - 0.0063 15.4 1.8 0.054 12.3 1.1 2.2 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 CCH62659.1 - 0.019 14.1 1.3 7.8 5.6 0.0 3.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CCH62659.1 - 0.04 13.5 0.1 0.04 13.5 0.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CCH62659.1 - 0.066 13.4 1.0 2 8.7 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 CCH62659.1 - 0.21 10.5 2.1 3.3 6.6 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 CCH62659.1 - 5.9 7.0 10.7 0.048 13.6 1.7 1.8 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain SLAC1 PF03595.12 CCH62660.1 - 4.2e-71 239.2 34.9 4.9e-71 239.0 24.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel GerA PF03323.8 CCH62660.1 - 0.17 9.9 5.7 0.39 8.7 4.0 1.6 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Sec62 PF03839.11 CCH62661.1 - 8.2e-52 175.8 3.0 1.4e-51 175.1 0.0 1.9 1 1 1 2 2 2 1 Translocation protein Sec62 DUF918 PF06033.6 CCH62661.1 - 0.017 14.6 0.4 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF918) MMR_HSR1 PF01926.18 CCH62662.1 - 7.4e-08 32.3 5.3 7.3e-07 29.1 2.8 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCH62662.1 - 2.2e-07 30.5 1.9 1.7e-06 27.5 1.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Abhydrolase_1 PF00561.15 CCH62663.1 - 8e-26 91.0 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCH62663.1 - 3.2e-14 53.3 0.0 5.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH62663.1 - 4.3e-08 33.0 0.0 1.5e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1648 PF07853.6 CCH62663.1 - 0.013 14.9 0.1 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) Cutinase PF01083.17 CCH62663.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.16 CCH62663.1 - 0.11 11.7 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Rad4 PF03835.10 CCH62664.1 - 2.4e-11 43.2 1.6 6.9e-11 41.7 1.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 CCH62664.1 - 1.7e-10 41.0 0.1 3.6e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Zn-ribbon_8 PF09723.5 CCH62664.1 - 0.014 15.3 0.6 6.3 6.8 0.0 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-TFIIB PF13453.1 CCH62664.1 - 0.04 13.1 1.4 0.13 11.5 1.0 1.9 1 1 0 1 1 1 0 Transcription factor zinc-finger YhfH PF14149.1 CCH62664.1 - 0.24 11.2 2.5 0.53 10.1 0.2 2.4 2 0 0 2 2 2 0 YhfH-like protein Zn_Tnp_IS1595 PF12760.2 CCH62664.1 - 0.26 11.1 5.3 1.4 8.7 3.7 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCH62664.1 - 2.7 7.5 8.0 8.8 5.9 0.5 2.8 2 1 0 2 2 2 0 zinc-ribbon domain Bax1-I PF01027.15 CCH62665.1 - 0.032 13.8 2.9 0.031 13.9 2.0 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 tRNA-synt_1b PF00579.20 CCH62666.1 - 8.6e-75 251.5 0.2 1.1e-74 251.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 CCH62666.1 - 0.009 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain NAD_synthase PF02540.12 CCH62666.1 - 0.045 12.6 0.0 0.12 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD synthase Romo1 PF10247.4 CCH62667.1 - 7.5e-27 93.3 7.8 9.5e-27 92.9 5.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.1 CCH62667.1 - 0.22 11.1 1.0 0.3 10.7 0.7 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain WD40 PF00400.27 CCH62668.1 - 0.001 18.8 0.0 0.71 9.8 0.0 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat NST1 PF13945.1 CCH62668.1 - 1.6 8.7 8.9 2.9 7.9 6.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator NPL4 PF05021.10 CCH62669.1 - 4.7e-117 390.5 0.0 6.9e-117 389.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CCH62669.1 - 2.7e-70 234.7 2.2 4.9e-70 233.8 1.5 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CCH62669.1 - 4.9e-07 29.9 0.0 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF1906 PF08924.6 CCH62669.1 - 0.0043 16.9 0.0 0.024 14.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1906) HSP70 PF00012.15 CCH62670.1 - 4.1e-150 500.5 1.6 6.3e-150 499.9 1.1 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH62670.1 - 3.4e-09 35.7 0.3 9.2e-09 34.3 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CCH62670.1 - 6.6 6.6 8.5 3 7.6 3.5 2.5 2 2 0 2 2 2 0 Cell division protein FtsA Oxidored-like PF09791.4 CCH62671.1 - 3.9e-22 77.4 2.5 6.2e-22 76.7 1.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Zn_clus PF00172.13 CCH62672.1 - 1.8e-09 37.3 12.3 1.8e-09 37.3 8.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3589 PF12141.3 CCH62673.1 - 5.4e-86 288.8 9.3 4.7e-85 285.7 6.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) Flocculin PF00624.13 CCH62675.1 - 3.8e-108 353.1 496.5 1.1e-14 54.0 15.4 23.6 24 1 0 24 24 24 15 Flocculin repeat GFO_IDH_MocA PF01408.17 CCH62676.1 - 2.6e-19 69.9 0.0 5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCH62676.1 - 1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DCP1 PF06058.8 CCH62677.1 - 1.3e-17 63.9 1.6 6.1e-10 39.2 0.0 3.1 1 1 1 3 3 3 3 Dcp1-like decapping family DUF3445 PF11927.3 CCH62677.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) Kelch_4 PF13418.1 CCH62677.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Galactose oxidase, central domain Spt20 PF12090.3 CCH62678.1 - 2.9e-45 153.8 30.1 2.9e-45 153.8 20.8 4.5 2 2 0 2 2 2 1 Spt20 family PEX11 PF05648.9 CCH62679.1 - 2.7e-59 200.1 4.8 3.1e-59 199.9 3.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sld5 PF05916.6 CCH62680.1 - 2e-08 34.4 0.0 2.6e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein NMD3 PF04981.8 CCH62680.1 - 0.16 11.0 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 NMD3 family TPR_11 PF13414.1 CCH62681.1 - 8e-32 108.7 20.2 3.4e-08 32.9 0.4 9.7 9 2 2 11 11 10 7 TPR repeat TPR_2 PF07719.12 CCH62681.1 - 5.6e-26 88.3 27.4 0.0011 18.6 0.0 13.9 15 1 0 15 15 13 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCH62681.1 - 7.7e-25 86.6 21.0 9.3e-06 25.5 0.2 11.9 7 4 3 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62681.1 - 1.9e-21 74.1 46.2 0.003 17.2 0.1 15.3 16 1 0 16 16 15 6 Tetratricopeptide repeat TPR_1 PF00515.23 CCH62681.1 - 4.2e-21 73.6 43.7 2.2e-05 23.8 0.1 14.1 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCH62681.1 - 3.5e-19 68.9 0.9 0.016 15.5 0.0 8.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCH62681.1 - 4.6e-16 59.0 0.0 0.14 12.8 0.1 9.2 7 2 4 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62681.1 - 2.4e-14 52.5 0.0 6.2 7.7 0.0 11.9 9 3 4 13 13 12 1 Tetratricopeptide repeat Apc3 PF12895.2 CCH62681.1 - 1.2e-13 50.9 18.3 0.12 12.5 0.0 9.4 6 3 4 10 10 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCH62681.1 - 2.1e-13 49.7 7.5 0.3 11.6 0.0 11.6 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCH62681.1 - 3.1e-09 36.2 8.7 18 5.8 0.0 10.3 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCH62681.1 - 1.5e-08 34.2 3.0 0.71 9.8 0.0 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCH62681.1 - 5.7e-07 28.8 16.5 0.095 12.5 0.0 9.9 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCH62681.1 - 2.4e-05 24.1 0.0 1.2 8.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 CCH62681.1 - 0.089 12.8 1.7 28 4.9 0.0 5.2 6 0 0 6 6 5 0 PPR repeat LAMTOR PF15454.1 CCH62682.1 - 2.1e-10 40.7 2.6 3.1e-10 40.1 1.8 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Ribosomal_L50 PF10501.4 CCH62683.1 - 1.5e-19 70.0 1.6 1.5e-19 70.0 1.1 1.6 2 0 0 2 2 2 1 Ribosomal subunit 39S DUF809 PF05663.6 CCH62683.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Snf7 PF03357.16 CCH62684.1 - 2.3e-34 118.2 21.1 3.8e-32 111.0 14.8 2.0 1 1 1 2 2 2 2 Snf7 Ist1 PF03398.9 CCH62684.1 - 6.9e-06 25.5 5.7 8.9e-06 25.2 3.9 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF87 PF01935.12 CCH62684.1 - 2.5 7.8 9.1 1.6 8.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 Ribosomal_S6 PF01250.12 CCH62685.1 - 2.1e-07 30.6 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 NAD_binding_10 PF13460.1 CCH62686.1 - 2.4e-21 76.5 0.0 2.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCH62686.1 - 2.6e-07 29.6 0.2 3.5e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCH62686.1 - 1.7e-06 28.3 0.0 3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCH62686.1 - 6.3e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 CCH62686.1 - 0.001 18.5 0.1 0.0031 16.9 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 CCH62686.1 - 0.0038 17.6 0.0 0.0084 16.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 CCH62686.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CCH62686.1 - 0.021 15.3 0.1 0.045 14.2 0.0 1.5 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 CCH62686.1 - 0.14 11.0 0.1 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Thymidylate_kin PF02223.12 CCH62687.1 - 4.6e-37 127.2 0.0 6.1e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CCH62687.1 - 0.022 14.6 0.0 0.035 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_L14e PF01929.12 CCH62688.1 - 8.5e-31 106.1 2.0 1.3e-30 105.5 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCH62688.1 - 0.00039 20.0 0.2 0.001 18.7 0.1 1.7 1 0 0 1 1 1 1 KOW motif TRAM_LAG1_CLN8 PF03798.11 CCH62689.1 - 7.5e-38 130.0 23.9 7.5e-38 130.0 16.6 2.3 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCH62689.1 - 1.7e-23 81.8 1.2 4.3e-23 80.5 0.8 1.7 1 0 0 1 1 1 1 TRAM1-like protein Sporozoite_P67 PF05642.6 CCH62689.1 - 0.028 12.2 7.2 0.041 11.7 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 CCH62689.1 - 0.077 12.6 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 CCH62689.1 - 0.13 12.4 9.8 0.27 11.4 6.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSP_II PF05432.6 CCH62689.1 - 0.15 11.3 8.6 0.28 10.4 5.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) YqfQ PF14181.1 CCH62689.1 - 0.33 10.9 1.9 0.53 10.3 1.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein RXT2_N PF08595.6 CCH62689.1 - 0.59 9.9 5.9 0.54 10.0 2.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 CCH62689.1 - 1 8.9 7.5 1.8 8.1 5.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 CCH62689.1 - 1.8 7.1 9.5 2.7 6.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 CCH62689.1 - 1.9 7.9 12.8 3.3 7.2 8.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CCH62689.1 - 2.4 7.3 6.1 3.6 6.7 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 CCH62689.1 - 3.1 6.8 6.2 4.9 6.2 4.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.7 CCH62689.1 - 4.8 4.9 9.6 7.1 4.4 6.7 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_S2 PF00318.15 CCH62690.1 - 2.2e-50 170.8 5.9 2.2e-50 170.8 4.1 2.3 2 1 0 2 2 2 1 Ribosomal protein S2 HECT PF00632.20 CCH62692.1 - 5.4e-70 236.0 2.2 5.4e-70 236.0 1.5 2.7 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 CCH62693.1 - 3.1e-71 239.5 0.0 6.5e-71 238.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62693.1 - 4.9e-48 163.4 0.0 1e-47 162.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCH62693.1 - 4.6e-22 78.1 0.0 4.6e-22 78.1 0.0 3.5 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 CCH62693.1 - 4.7e-05 22.4 0.0 9.1e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCH62693.1 - 0.21 11.2 0.0 1.6 8.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Smr PF01713.16 CCH62694.1 - 7.7e-12 45.2 0.0 1.9e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CCH62694.1 - 7.9e-05 22.0 0.9 0.0031 16.9 0.3 2.6 2 0 0 2 2 2 1 CUE domain Glutaredoxin2_C PF04399.8 CCH62695.1 - 0.00021 20.8 4.0 0.00041 19.9 2.8 1.4 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain bZIP_1 PF00170.16 CCH62695.1 - 0.00029 20.7 23.1 0.00029 20.7 16.0 2.3 2 1 0 2 2 2 1 bZIP transcription factor V_ATPase_I PF01496.14 CCH62695.1 - 0.016 13.1 4.6 0.022 12.6 3.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 CCH62695.1 - 0.14 11.8 15.3 0.28 10.9 10.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.10 CCH62695.1 - 0.23 11.2 24.6 0.08 12.7 14.7 2.0 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 CCH62695.1 - 0.28 11.4 11.0 0.68 10.2 7.7 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 CCH62695.1 - 0.55 9.2 8.9 0.88 8.5 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Sec62 PF03839.11 CCH62695.1 - 0.93 8.8 5.6 1.6 8.1 3.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.1 CCH62695.1 - 0.99 8.3 4.6 1.5 7.7 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ExbD PF02472.11 CCH62695.1 - 2.4 8.1 6.8 5.8 6.9 0.5 2.4 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR IncA PF04156.9 CCH62695.1 - 4.3 6.8 13.7 11 5.5 8.5 2.3 2 1 0 2 2 2 0 IncA protein IpaD PF06511.6 CCH62695.1 - 7.4 5.4 8.5 4 6.3 3.1 2.2 2 0 0 2 2 2 0 Invasion plasmid antigen IpaD Bap31 PF05529.7 CCH62695.1 - 8.4 5.8 13.1 16 4.9 9.1 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like EMP70 PF02990.11 CCH62697.1 - 6.4e-63 212.9 51.0 2.6e-62 210.9 30.0 3.9 2 1 0 2 2 2 1 Endomembrane protein 70 LSM PF01423.17 CCH62698.1 - 4.8e-15 54.8 0.8 9.4e-15 53.9 0.5 1.5 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCH62698.1 - 0.00018 21.3 0.0 0.0005 19.9 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Zip PF02535.17 CCH62698.1 - 0.86 8.5 7.8 0.91 8.4 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 CCH62698.1 - 1.4 7.0 14.3 1.6 6.8 9.9 1.2 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 CCH62699.1 - 7.1e-28 95.4 9.8 6.6e-07 28.9 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CCH62699.1 - 0.0032 15.6 1.0 0.09 10.8 0.1 2.7 2 1 1 4 4 4 2 Nucleoporin Nup120/160 MAM1 PF10434.4 CCH62700.1 - 6.5e-29 100.9 21.1 6.5e-29 100.9 14.6 2.4 1 1 1 2 2 2 2 Monopolin complex protein MAM1 Atg8 PF02991.11 CCH62701.1 - 1.3e-49 166.5 0.1 1.4e-49 166.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CCH62701.1 - 1.8e-06 28.0 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 PAP_central PF04928.12 CCH62702.1 - 0.26 10.0 1.4 0.36 9.6 1.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain tRNA-synt_1 PF00133.17 CCH62703.1 - 5.4e-233 774.3 2.6 5.9e-233 774.2 0.5 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCH62703.1 - 7.2e-28 97.2 0.1 2.4e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCH62703.1 - 1.3e-20 73.4 3.2 5.5e-07 28.5 0.5 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CCH62703.1 - 0.0001 21.5 0.0 0.00064 18.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Ribosomal_S8e PF01201.17 CCH62704.1 - 4e-50 169.3 1.9 4.6e-50 169.1 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Adeno_VII PF03228.9 CCH62704.1 - 0.2 12.2 0.2 0.2 12.2 0.1 2.0 2 0 0 2 2 2 0 Adenoviral core protein VII zf-CSL PF05207.8 CCH62705.1 - 2.5e-19 68.5 1.4 3.1e-19 68.2 1.0 1.1 1 0 0 1 1 1 1 CSL zinc finger Nudix_N_2 PF14803.1 CCH62705.1 - 0.037 13.7 0.7 0.059 13.0 0.5 1.3 1 0 0 1 1 1 0 Nudix N-terminal Zn-ribbon_8 PF09723.5 CCH62705.1 - 0.13 12.2 2.0 0.23 11.4 1.4 1.4 1 1 0 1 1 1 0 Zinc ribbon domain ADH_zinc_N_2 PF13602.1 CCH62706.1 - 7.1e-10 39.8 0.0 1.5e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH62706.1 - 2.7e-05 23.8 0.0 4.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rad51 PF08423.6 CCH62707.1 - 3e-137 455.6 0.0 5.2e-137 454.8 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCH62707.1 - 3.1e-14 52.8 0.1 4.8e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CCH62707.1 - 9.6e-12 44.5 0.2 2.5e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CCH62707.1 - 1.2e-11 44.5 0.5 3.1e-11 43.2 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CCH62707.1 - 4.9e-08 32.3 0.3 1.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 KaiC Sec7 PF01369.15 CCH62708.1 - 7.4e-19 68.1 1.5 3.7e-18 65.8 1.0 2.3 1 0 0 1 1 1 1 Sec7 domain Proteasome PF00227.21 CCH62709.1 - 5.5e-42 143.2 0.0 6.6e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.5 CCH62710.1 - 1.4e-10 40.7 5.6 1.4e-10 40.7 3.9 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CCH62710.1 - 0.032 14.1 2.2 0.35 10.8 1.8 2.1 1 1 1 2 2 2 0 CHCH domain DUF2362 PF10154.4 CCH62710.1 - 0.061 11.9 1.0 0.061 11.9 0.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) NDUF_B7 PF05676.8 CCH62710.1 - 0.2 11.1 3.3 0.37 10.2 2.2 1.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Bd3614_N PF14442.1 CCH62710.1 - 0.23 11.4 3.2 0.26 11.2 0.4 1.9 1 1 1 2 2 2 0 Bd3614-like deaminase N-terminal Mac PF12464.3 CCH62710.1 - 0.73 9.8 5.3 0.32 11.0 1.5 2.0 2 0 0 2 2 2 0 Maltose acetyltransferase Meth_synt_2 PF01717.13 CCH62711.1 - 2e-143 477.2 0.0 2.4e-136 453.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCH62711.1 - 4.7e-124 413.6 0.0 1e-110 369.9 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain DUF1840 PF08895.6 CCH62711.1 - 0.021 14.8 0.3 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Na_Ca_ex PF01699.19 CCH62712.1 - 2.3e-27 95.3 30.2 1.7e-15 56.8 6.4 3.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CCH62712.1 - 2.2e-11 43.9 5.3 2.2e-11 43.9 3.7 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF307) DUF3270 PF11674.3 CCH62712.1 - 0.051 13.5 4.2 1.8 8.6 0.1 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) CDC50 PF03381.10 CCH62714.1 - 6e-90 301.1 2.5 8.8e-90 300.6 1.7 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family AAA PF00004.24 CCH62715.1 - 2.9e-52 176.3 0.0 1.2e-44 151.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCH62715.1 - 0.00012 22.2 0.2 0.012 15.7 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CCH62715.1 - 0.00018 22.3 0.0 0.0034 18.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 CCH62715.1 - 0.00024 20.0 0.0 0.00062 18.7 0.0 1.6 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 CCH62715.1 - 0.00046 19.6 0.3 0.012 15.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CCH62715.1 - 0.0015 18.4 0.0 0.023 14.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCH62715.1 - 0.0015 17.6 0.0 0.0046 16.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCH62715.1 - 0.003 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CCH62715.1 - 0.0039 16.9 0.0 0.033 13.9 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH62715.1 - 0.0041 17.1 0.1 0.093 12.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCH62715.1 - 0.0074 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CCH62715.1 - 0.0079 16.3 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.1 CCH62715.1 - 0.015 15.2 0.1 0.086 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CCH62715.1 - 0.016 14.4 0.1 0.034 13.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCH62715.1 - 0.063 13.5 0.0 0.3 11.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCH62715.1 - 0.23 11.3 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.14 CCH62716.1 - 1.4e-80 270.8 0.0 2e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.14 CCH62717.1 - 1.5e-44 151.1 0.0 1.9e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_5 PF13893.1 CCH62718.1 - 1.5e-06 27.9 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.20 CCH62719.1 - 4.6e-32 109.7 8.4 8.2e-21 73.7 0.2 2.9 3 0 0 3 3 3 2 Bromodomain Sox_C_TAD PF12067.3 CCH62719.1 - 0.067 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Sox C-terminal transactivation domain DUF2025 PF09634.5 CCH62719.1 - 0.085 12.6 0.2 0.53 10.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2025) adh_short PF00106.20 CCH62720.1 - 2.5e-65 219.4 0.5 1.3e-31 109.8 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCH62720.1 - 1.5e-30 106.1 0.1 2e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CCH62720.1 - 5.9e-28 96.7 0.0 1.2e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 CCH62720.1 - 1.2e-18 67.7 0.1 6.3e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 CCH62720.1 - 5.2e-06 26.2 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase ELFV_dehydrog PF00208.16 CCH62720.1 - 0.0057 16.2 4.5 0.57 9.7 0.1 2.4 2 0 0 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 CCH62720.1 - 0.074 12.6 2.6 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain BmKX PF09132.5 CCH62720.1 - 0.82 9.5 2.7 0.49 10.2 0.2 1.8 2 0 0 2 2 2 0 BmKX Adap_comp_sub PF00928.16 CCH62721.1 - 8.3e-35 120.1 0.1 6.7e-34 117.1 0.0 2.1 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Myc_N PF01056.13 CCH62721.1 - 0.0024 17.0 1.2 0.0055 15.9 0.8 1.5 1 0 0 1 1 1 1 Myc amino-terminal region Prothymosin PF03247.9 CCH62721.1 - 0.19 11.8 22.3 0.027 14.6 7.9 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family LAT PF15234.1 CCH62721.1 - 0.44 9.9 3.4 0.95 8.8 2.3 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells PBP_sp32 PF07222.7 CCH62721.1 - 1.6 7.8 5.6 2.9 6.9 3.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ribosomal_60s PF00428.14 CCH62721.1 - 2.5 8.5 10.1 5.2 7.5 7.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein SNF5 PF04855.7 CCH62722.1 - 1.1e-64 218.2 1.7 1.1e-64 218.2 1.2 5.5 4 2 0 4 4 4 1 SNF5 / SMARCB1 / INI1 Tctex-1 PF03645.8 CCH62722.1 - 0.034 13.9 0.1 0.034 13.9 0.1 4.1 4 0 0 4 4 4 0 Tctex-1 family Mito_carr PF00153.22 CCH62723.1 - 3.4e-62 206.1 3.6 1.8e-22 78.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.17 CCH62724.1 - 1e-74 251.6 0.0 1.2e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family She2p PF11435.3 CCH62725.1 - 2.7e-63 213.0 13.2 4.4e-63 212.3 9.1 1.3 1 0 0 1 1 1 1 RNA binding protein She2p GCR1_C PF12550.3 CCH62726.1 - 1.1e-20 73.2 0.0 3.7e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Mur_ligase_M PF08245.7 CCH62727.1 - 7.5e-07 29.3 0.3 1.8e-06 28.1 0.2 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CCH62727.1 - 0.11 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TPR_12 PF13424.1 CCH62728.1 - 3.9e-07 29.9 7.9 0.0012 18.7 0.8 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62728.1 - 3.6e-05 23.3 4.1 0.39 10.7 0.6 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH62728.1 - 0.00017 21.1 0.3 0.12 12.2 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62728.1 - 0.00031 21.1 2.0 1.2 9.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCH62728.1 - 0.0014 18.1 5.1 3.1 7.5 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCH62728.1 - 0.0041 17.4 2.9 0.04 14.3 0.6 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCH62728.1 - 0.0045 17.3 4.4 1.2 9.5 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCH62728.1 - 0.016 14.8 9.4 0.13 11.9 1.0 3.2 4 0 0 4 4 4 0 TPR repeat TPR_10 PF13374.1 CCH62728.1 - 0.02 14.8 4.2 0.44 10.5 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62728.1 - 0.029 14.1 12.4 0.31 10.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Herpes_U44 PF04533.8 CCH62728.1 - 0.061 12.5 0.7 0.12 11.6 0.5 1.4 1 0 0 1 1 1 0 Herpes virus U44 protein TPR_16 PF13432.1 CCH62728.1 - 0.17 12.5 4.3 4.3 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCH62728.1 - 0.53 10.4 4.5 4.9 7.3 0.5 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M3 PF01432.15 CCH62729.1 - 1.6e-130 436.2 0.0 2e-130 435.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CCH62729.1 - 0.15 11.4 0.4 0.24 10.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like SAC3_GANP PF03399.11 CCH62730.1 - 1.7e-32 112.6 10.9 2.7e-32 112.0 7.5 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CCH62730.1 - 0.074 13.3 10.3 1.5 9.1 6.0 3.3 2 1 0 2 2 2 0 PCI domain PX PF00787.19 CCH62731.1 - 5.9e-06 26.0 0.3 7.3e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 PX domain Mito_carr PF00153.22 CCH62732.1 - 7.4e-71 233.9 8.8 3.1e-24 84.4 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF500 PF04366.7 CCH62732.1 - 0.00081 18.8 0.7 0.0013 18.1 0.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Fip1 PF05182.8 CCH62734.1 - 3.9e-21 74.0 1.0 8.1e-21 73.0 0.7 1.5 1 0 0 1 1 1 1 Fip1 motif eIF-5_eIF-2B PF01873.12 CCH62735.1 - 3.9e-41 139.6 0.0 7.2e-41 138.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CCH62735.1 - 1.8e-27 95.1 0.0 1.8e-27 95.1 0.0 2.8 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 CCH62735.1 - 0.25 11.3 1.0 0.6 10.1 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain TPR_2 PF07719.12 CCH62736.1 - 1.3e-05 24.6 1.8 0.00021 20.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCH62736.1 - 0.004 16.7 0.1 0.016 14.8 0.1 2.2 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CCH62736.1 - 0.011 15.3 0.7 0.15 11.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat dsrm PF00035.20 CCH62737.1 - 4.4e-05 23.9 0.4 0.001 19.5 0.0 2.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF3666 PF12408.3 CCH62737.1 - 0.029 13.4 0.0 0.12 11.4 0.0 2.1 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase SIS PF01380.17 CCH62738.1 - 1.2e-57 193.1 0.0 2e-29 101.8 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCH62738.1 - 1e-27 96.8 0.0 6.4e-19 67.8 0.0 2.3 1 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCH62738.1 - 6.9e-17 61.6 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCH62738.1 - 1.3e-10 41.0 0.0 2.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCH62738.1 - 6.4e-10 38.1 0.2 1.1e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 CCH62738.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 SIS domain Evr1_Alr PF04777.8 CCH62739.1 - 3.3e-24 84.5 0.3 4.9e-24 84.0 0.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family G-gamma PF00631.17 CCH62740.1 - 3.6e-18 65.0 0.1 5e-18 64.5 0.1 1.2 1 0 0 1 1 1 1 GGL domain PUB PF09409.5 CCH62740.1 - 0.01 15.5 0.2 0.012 15.3 0.1 1.2 1 0 0 1 1 1 0 PUB domain PCI PF01399.22 CCH62742.1 - 8.8e-10 38.8 0.2 1.3e-08 35.1 0.0 2.6 3 0 0 3 3 3 1 PCI domain V-ATPase_H_N PF03224.9 CCH62743.1 - 3e-47 161.2 13.0 3e-47 161.2 9.0 1.6 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCH62743.1 - 1.8e-37 127.8 0.2 1.8e-37 127.8 0.2 3.5 3 1 1 4 4 4 1 V-ATPase subunit H Gln-synt_C PF00120.19 CCH62744.1 - 2.5e-65 220.1 0.0 3e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CCH62744.1 - 2.4e-19 68.7 0.0 4.1e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain NuA4 PF09340.5 CCH62745.1 - 1.1e-19 69.8 6.6 5.3e-19 67.6 4.6 2.1 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Cast PF10174.4 CCH62745.1 - 0.0017 16.4 0.3 0.0021 16.2 0.2 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Tmemb_cc2 PF10267.4 CCH62745.1 - 0.032 12.8 4.7 0.044 12.3 3.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1754 PF08555.5 CCH62745.1 - 1.3 9.6 4.7 0.53 10.9 1.4 1.8 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF4407 PF14362.1 CCH62745.1 - 3.8 6.3 7.6 5.2 5.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIM24 PF01987.12 CCH62746.1 - 1.6e-06 27.7 0.0 7e-06 25.6 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 tRNA-synt_His PF13393.1 CCH62747.1 - 5.1e-38 130.8 0.0 2.5e-33 115.4 0.0 2.0 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CCH62747.1 - 1.2e-19 70.5 0.0 1.3e-18 67.1 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH62747.1 - 2.1e-13 50.0 0.0 4.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CCH62747.1 - 0.0012 17.7 0.1 0.011 14.5 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CCH62747.1 - 0.0076 15.4 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) OGG_N PF07934.7 CCH62747.1 - 0.078 12.9 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Cid2 PF09774.4 CCH62748.1 - 2.2e-31 109.0 10.7 2.6e-31 108.7 7.4 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Lgl_C PF08596.5 CCH62749.1 - 9.3e-109 363.4 0.3 1.6e-108 362.6 0.2 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCH62749.1 - 0.004 16.9 4.2 7.5 6.6 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Pkinase PF00069.20 CCH62750.1 - 1.5e-62 211.1 0.0 3.6e-62 209.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62750.1 - 5.8e-34 117.3 0.0 1.2e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CCH62750.1 - 1.5e-27 95.1 28.3 7e-16 57.7 4.5 2.9 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 CCH62750.1 - 2.3e-20 72.0 32.1 9e-12 44.5 7.8 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CCH62750.1 - 2.2e-09 37.6 0.9 2.2e-09 37.6 0.7 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCH62750.1 - 0.0068 15.3 1.6 0.0092 14.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF4206 PF13901.1 CCH62750.1 - 8.7 5.8 24.5 0.27 10.7 4.5 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4206) SopA PF13981.1 CCH62751.1 - 0.016 15.2 0.1 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 SopA-like central domain EB_dh PF09459.5 CCH62751.1 - 0.038 13.4 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase zf-RING_2 PF13639.1 CCH62751.1 - 1.4 8.7 11.8 0.66 9.8 2.9 3.3 3 0 0 3 3 3 0 Ring finger domain HLH PF00010.21 CCH62752.1 - 5.9e-12 45.0 1.7 1.6e-11 43.7 1.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRESAN PF09687.5 CCH62752.1 - 0.39 10.7 2.9 4.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Got1 PF04178.7 CCH62753.1 - 1.1e-31 109.3 15.3 1.5e-31 108.9 10.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.11 CCH62753.1 - 0.00046 19.0 8.7 0.00053 18.8 6.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 CCH62753.1 - 4.3 7.4 7.2 0.46 10.6 1.7 1.7 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Arrestin_C PF02752.17 CCH62754.1 - 4.2e-19 69.0 2.4 4.2e-19 69.0 1.7 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCH62754.1 - 2.7e-06 27.2 0.3 0.00013 21.8 0.2 2.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Adaptin_N PF01602.15 CCH62755.1 - 3.2e-104 349.1 15.1 3.8e-104 348.8 10.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CCH62755.1 - 6.9e-10 39.2 1.1 1.3e-09 38.4 0.2 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain Xpo1 PF08389.7 CCH62755.1 - 0.048 13.5 5.1 1.2 9.0 0.1 3.4 2 1 1 3 3 3 0 Exportin 1-like protein TB2_DP1_HVA22 PF03134.14 CCH62756.1 - 7.1e-31 105.8 3.6 1.2e-30 105.0 2.5 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2207 PF09972.4 CCH62756.1 - 1.8 7.0 9.1 3.2 6.2 6.3 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) CtnDOT_TraJ PF07863.6 CCH62756.1 - 2.9 8.4 5.8 4.5 7.8 3.4 1.8 1 1 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Glyco_hydro_65m PF03632.10 CCH62757.1 - 1.1e-95 320.5 0.3 5.4e-95 318.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CCH62757.1 - 7.5e-28 97.5 7.2 1.7e-27 96.3 5.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 CCH62757.1 - 4.4e-12 45.8 0.2 3.7e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain ATP-synt_ab PF00006.20 CCH62758.1 - 6.5e-69 231.7 0.0 1e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCH62758.1 - 1.3e-26 93.2 0.2 3.8e-26 91.7 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCH62758.1 - 2.6e-18 65.9 0.9 7e-18 64.6 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ArfGap PF01412.13 CCH62759.1 - 1.3e-33 115.2 1.2 1.3e-33 115.2 0.8 2.6 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Rox3 PF08633.5 CCH62760.1 - 6.9e-53 179.8 11.7 3.3e-50 171.0 8.1 2.0 1 1 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.13 CCH62761.1 - 7.4e-46 154.7 3.7 8.6e-46 154.5 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 CCH62761.1 - 0.15 11.7 0.8 0.24 11.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Motile_Sperm PF00635.21 CCH62762.1 - 2.6e-27 94.6 0.0 5.1e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain PapD-like PF14874.1 CCH62762.1 - 0.016 15.1 0.1 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 Flagellar-associated PapD-like Peptidase_M24 PF00557.19 CCH62763.1 - 4.3e-50 170.1 0.0 6.2e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SH3_1 PF00018.23 CCH62764.1 - 5.2e-11 41.7 0.1 1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH62764.1 - 1.2e-08 34.3 0.0 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCH62764.1 - 5.3e-08 32.2 0.0 9e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain NT-C2 PF10358.4 CCH62766.1 - 7e-40 135.8 9.0 7.2e-26 90.3 1.3 2.7 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins SH3_1 PF00018.23 CCH62767.1 - 9.2e-14 50.5 0.3 2e-13 49.5 0.2 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 CCH62767.1 - 1e-13 51.3 4.9 1.3e-13 51.0 0.0 3.8 3 0 0 3 3 3 1 PH domain SH3_9 PF14604.1 CCH62767.1 - 1.4e-09 37.3 0.1 2.6e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 CCH62767.1 - 2.8e-08 33.4 0.1 5.9e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 CCH62767.1 - 3.3e-06 27.3 0.0 3.3e-06 27.3 0.0 5.2 5 1 0 5 5 5 1 Pleckstrin homology domain PH_8 PF15409.1 CCH62767.1 - 0.00018 21.5 0.0 0.0041 17.1 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 CCH62767.1 - 0.00042 19.7 0.0 0.00094 18.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CCH62767.1 - 0.008 16.3 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MIP PF00230.15 CCH62768.1 - 9.5e-47 159.3 12.4 1.2e-46 159.0 8.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein Snf7 PF03357.16 CCH62769.1 - 1.3e-31 109.3 12.5 1.5e-31 109.0 8.7 1.0 1 0 0 1 1 1 1 Snf7 HHH_2 PF12826.2 CCH62769.1 - 0.032 14.0 0.6 0.058 13.2 0.1 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Mating_N PF12731.2 CCH62769.1 - 0.037 13.8 0.3 2.1 8.2 0.0 2.4 1 1 1 2 2 2 0 Mating-type protein beta 1 UvsY PF11056.3 CCH62769.1 - 0.1 12.7 9.0 0.4 10.8 3.5 2.2 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY Mit_KHE1 PF10173.4 CCH62769.1 - 1 9.1 5.3 1.8 8.4 3.7 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RRF_GI PF12614.3 CCH62769.1 - 3.1 7.6 6.1 2.4 8.0 1.9 2.1 2 0 0 2 2 2 0 Ribosome recycling factor AAA PF00004.24 CCH62770.1 - 1.1e-10 41.7 1.3 1.9e-10 41.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCH62770.1 - 1.9e-08 33.4 9.1 1.5e-06 27.1 0.1 2.9 3 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CCH62770.1 - 7e-07 29.1 0.9 2.3e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH62770.1 - 5.9e-06 27.0 0.0 2.2e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCH62770.1 - 7e-06 25.8 0.0 3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCH62770.1 - 9.9e-06 24.7 0.0 2.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCH62770.1 - 1.8e-05 24.8 0.0 9.1e-05 22.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCH62770.1 - 2.2e-05 24.5 0.0 6.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CCH62770.1 - 0.0013 19.0 1.0 0.0033 17.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CCH62770.1 - 0.003 17.4 1.0 0.0078 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCH62770.1 - 0.0048 16.9 0.1 0.019 14.9 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain SKI PF01202.17 CCH62770.1 - 0.0073 16.1 0.7 0.051 13.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.1 CCH62770.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 CCH62770.1 - 0.032 13.4 0.0 0.032 13.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Band_3_cyto PF07565.8 CCH62770.1 - 0.099 12.1 4.1 0.2 11.1 2.9 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIR PF00399.14 CCH62772.1 - 9.9e-07 27.8 3.3 9.9e-07 27.8 2.3 2.3 2 0 0 2 2 2 1 Yeast PIR protein repeat Elong-fact-P_C PF09285.6 CCH62772.1 - 8.8 5.7 7.2 3 7.2 1.0 2.7 2 1 1 3 3 3 0 Elongation factor P, C-terminal Utp11 PF03998.8 CCH62773.1 - 3.7e-59 200.4 22.6 4.2e-59 200.2 15.7 1.0 1 0 0 1 1 1 1 Utp11 protein SpoIIID PF12116.3 CCH62773.1 - 0.02 14.8 1.4 0.05 13.5 0.0 2.4 2 1 0 2 2 2 0 Stage III sporulation protein D RNA_binding PF01877.12 CCH62773.1 - 0.075 13.0 0.5 0.075 13.0 0.4 2.1 2 1 1 3 3 3 0 RNA binding ADH_N PF08240.7 CCH62774.1 - 3.2e-29 100.8 1.5 3.7e-29 100.6 0.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCH62774.1 - 2.7e-27 94.8 0.2 4.1e-27 94.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 CCH62775.1 - 6.4e-73 245.1 0.0 2e-72 243.4 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62775.1 - 2.7e-34 118.4 0.0 4.5e-32 111.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCH62775.1 - 0.003 17.3 0.0 0.0095 15.6 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCH62775.1 - 0.04 12.9 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M18 PF02127.10 CCH62776.1 - 3e-136 454.3 0.0 3.5e-136 454.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Aminotran_1_2 PF00155.16 CCH62778.1 - 4e-75 253.0 0.0 4.6e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M41 PF01434.13 CCH62779.1 - 1.1e-72 244.0 1.0 1.2e-71 240.5 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CCH62779.1 - 2.7e-42 144.1 0.0 7e-42 142.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCH62779.1 - 7.3e-10 39.0 3.0 7.3e-10 39.0 2.1 2.8 1 1 1 2 2 2 1 FtsH Extracellular AAA_17 PF13207.1 CCH62779.1 - 0.00013 22.7 2.3 0.00038 21.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 CCH62779.1 - 0.00015 20.6 0.3 0.0062 15.2 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 CCH62779.1 - 0.00069 19.7 0.1 0.16 12.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CCH62779.1 - 0.0013 18.6 1.7 0.0056 16.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCH62779.1 - 0.0015 17.6 0.0 0.0033 16.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCH62779.1 - 0.0029 17.3 0.6 0.016 14.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCH62779.1 - 0.0048 16.6 0.4 0.012 15.3 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CCH62779.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CCH62779.1 - 0.02 14.9 0.1 0.09 12.7 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CCH62779.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCH62779.1 - 0.046 13.1 1.1 0.21 10.9 0.2 2.2 1 1 1 2 2 2 0 AAA domain MEDS PF14417.1 CCH62779.1 - 0.12 11.3 1.8 0.28 10.2 1.2 1.5 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Claudin_2 PF13903.1 CCH62779.1 - 0.2 11.3 0.9 0.49 10.0 0.1 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction AAA_18 PF13238.1 CCH62779.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.7 3 2 0 3 3 3 0 AAA domain RP-C_C PF11800.3 CCH62779.1 - 9.3 5.8 9.2 0.4 10.3 1.9 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region CRC_subunit PF08624.5 CCH62781.1 - 1.4e-54 183.7 0.1 3e-54 182.7 0.1 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PRP1_N PF06424.7 CCH62781.1 - 0.15 12.4 8.4 0.35 11.1 5.8 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal UTP15_C PF09384.5 CCH62782.1 - 3.6e-51 172.7 0.3 5.3e-51 172.1 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CCH62782.1 - 6.8e-22 76.4 3.2 5.5e-06 26.0 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCH62782.1 - 0.0029 17.3 0.0 0.68 9.7 0.0 3.8 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Drc1-Sld2 PF11719.3 CCH62783.1 - 3.4e-48 164.8 41.0 7.6e-48 163.6 28.4 1.5 1 1 0 1 1 1 1 DNA replication and checkpoint protein Lipid_DES PF08557.5 CCH62783.1 - 0.066 12.4 1.0 0.14 11.3 0.7 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Apc13p PF05839.6 CCH62783.1 - 0.69 9.9 4.8 2.3 8.2 0.4 2.6 2 0 0 2 2 2 0 Apc13p protein PBP1_TM PF14812.1 CCH62783.1 - 1.6 9.0 13.8 3.5 7.9 2.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2072 PF09845.4 CCH62784.1 - 0.35 10.7 4.1 0.31 10.9 1.1 2.1 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) MMR_HSR1 PF01926.18 CCH62785.1 - 2.9e-12 46.5 0.2 1.1e-11 44.7 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCH62785.1 - 2.5e-08 33.2 0.0 3.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CCH62785.1 - 0.00099 18.4 0.1 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCH62785.1 - 0.0044 17.5 0.1 0.048 14.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein PhaP_Bmeg PF09602.5 CCH62785.1 - 0.0063 16.3 0.4 0.28 11.0 0.0 2.2 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) AAA_25 PF13481.1 CCH62785.1 - 0.0089 15.4 0.0 0.031 13.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain IIGP PF05049.8 CCH62785.1 - 0.01 14.6 0.0 0.019 13.8 0.0 1.4 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 CCH62785.1 - 0.016 15.4 3.2 0.059 13.6 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 CCH62785.1 - 0.022 15.5 0.8 0.1 13.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 CCH62785.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 CCH62785.1 - 0.037 13.0 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Septin NTPase_1 PF03266.10 CCH62785.1 - 0.052 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 NTPase Methyltrn_RNA_4 PF09936.4 CCH62785.1 - 0.053 13.0 0.1 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase MobB PF03205.9 CCH62785.1 - 0.059 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCH62785.1 - 0.086 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.22 CCH62785.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CCH62785.1 - 0.12 12.6 0.2 0.28 11.4 0.0 1.7 1 1 1 2 2 2 0 ABC transporter KTI12 PF08433.5 CCH62786.1 - 8.4e-89 297.3 0.3 9.7e-89 297.1 0.2 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 CCH62786.1 - 9.1e-06 25.6 0.0 2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCH62786.1 - 2.3e-05 24.7 0.6 5.3e-05 23.5 0.4 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCH62786.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_14 PF13173.1 CCH62786.1 - 0.0075 16.1 0.5 0.039 13.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCH62786.1 - 0.013 16.3 0.0 0.022 15.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Elong_Iki1 PF10483.4 CCH62786.1 - 0.025 13.9 0.3 0.044 13.1 0.2 1.4 1 0 0 1 1 1 0 Elongator subunit Iki1 AAA_22 PF13401.1 CCH62786.1 - 0.05 13.7 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCH62786.1 - 0.073 11.9 0.4 0.19 10.6 0.0 1.8 2 1 0 2 2 2 0 Type II/IV secretion system protein CPT PF07931.7 CCH62786.1 - 0.11 12.0 0.1 3.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Oligomerisation PF02410.10 CCH62787.1 - 2.9e-19 68.9 0.2 9.7e-19 67.2 0.0 2.0 2 0 0 2 2 2 1 Oligomerisation domain mRNA_stabil PF13929.1 CCH62787.1 - 3.6e-15 55.6 15.2 7.1e-15 54.7 10.6 1.5 1 0 0 1 1 1 1 mRNA stabilisation BAF1_ABF1 PF04684.8 CCH62788.1 - 6.7e-82 275.9 14.1 2.6e-53 181.6 0.7 7.4 3 2 3 7 7 7 5 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CCH62788.1 - 0.0003 20.2 0.1 0.0006 19.3 0.1 1.4 1 0 0 1 1 1 1 MuDR family transposase XPG_N PF00752.12 CCH62789.1 - 5.6e-39 132.4 1.2 6e-39 132.3 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 CCH62789.1 - 2e-27 95.0 0.0 6.1e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCH62789.1 - 3e-07 30.5 0.0 3e-07 30.5 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 CCH62789.1 - 0.00044 20.0 0.0 0.0045 16.8 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 CCH62789.1 - 0.0033 17.5 0.0 0.02 15.0 0.0 2.3 3 0 0 3 3 3 1 Helix-hairpin-helix domain 5_3_exonuc_N PF02739.11 CCH62789.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain AAA_23 PF13476.1 CCH62789.1 - 0.044 14.1 5.1 4.6 7.5 1.6 2.2 2 0 0 2 2 2 0 AAA domain Transposase_20 PF02371.11 CCH62789.1 - 0.093 12.8 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family HXXSHH PF07586.6 CCH62789.1 - 0.15 10.9 1.4 0.26 10.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AP_endonuc_2 PF01261.19 CCH62790.1 - 3.2e-26 91.9 0.0 4.4e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF4407 PF14362.1 CCH62790.1 - 0.71 8.7 3.6 1.1 8.1 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Host_attach PF10116.4 CCH62790.1 - 0.92 9.7 5.0 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein required for attachment to host cells Pkinase PF00069.20 CCH62791.1 - 9.9e-55 185.4 0.0 1.4e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62791.1 - 7.9e-20 71.0 0.0 5.9e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCH62791.1 - 0.044 12.5 0.2 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Aldose_epim PF01263.15 CCH62792.1 - 3.9e-47 160.8 0.4 4.7e-47 160.5 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase CS PF04969.11 CCH62793.1 - 0.58 10.7 5.1 0.31 11.6 2.1 1.8 2 1 0 2 2 2 0 CS domain zf-MYND PF01753.13 CCH62794.1 - 1.6e-08 34.2 17.6 3.3e-08 33.2 12.2 1.5 1 0 0 1 1 1 1 MYND finger SPRY PF00622.23 CCH62795.1 - 6.5e-09 35.9 0.0 1.4e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 SPRY domain RRN3 PF05327.6 CCH62796.1 - 1.7e-182 607.4 12.5 2.2e-182 607.1 8.7 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.8 CCH62796.1 - 0.0034 17.3 9.5 0.0054 16.6 6.6 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1539 PF07560.6 CCH62796.1 - 0.47 10.3 9.2 0.17 11.7 0.4 3.8 2 2 0 2 2 2 0 Domain of Unknown Function (DUF1539) Sigma70_ner PF04546.8 CCH62796.1 - 1.3 8.5 17.0 3.5 7.1 11.8 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.7 CCH62796.1 - 8.2 5.6 22.4 16 4.6 15.5 1.4 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.20 CCH62797.1 - 7.1e-69 231.8 0.0 3e-68 229.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62797.1 - 7.8e-30 103.8 0.0 1.9e-29 102.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCH62797.1 - 1.1e-09 38.6 0.2 1.1e-09 38.6 0.2 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCH62797.1 - 0.0019 17.2 0.0 0.0045 16.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCH62797.1 - 0.058 12.4 0.1 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCH62797.1 - 0.27 10.9 0.0 0.43 10.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PGM_PMM_I PF02878.11 CCH62798.1 - 1.7e-34 118.2 0.1 3.1e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCH62798.1 - 1.6e-23 82.9 0.0 2.7e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCH62798.1 - 4.3e-14 52.7 0.1 1.4e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCH62798.1 - 1.3e-07 31.5 0.0 2.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain TPP_enzyme_N PF02776.13 CCH62800.1 - 2.7e-60 202.7 0.1 8.8e-60 201.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCH62800.1 - 2e-50 170.3 0.0 1.2e-48 164.5 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCH62800.1 - 8.1e-37 126.0 0.3 3.9e-36 123.8 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 CCH62800.1 - 0.045 13.2 0.1 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg PIR PF00399.14 CCH62801.1 - 4.4e-40 133.6 70.3 3e-08 32.7 5.2 6.3 5 0 0 5 5 5 5 Yeast PIR protein repeat LeuA_dimer PF08502.5 CCH62801.1 - 3.9 7.2 11.7 16 5.3 0.3 3.1 1 1 2 3 3 3 0 LeuA allosteric (dimerisation) domain TFIIA PF03153.8 CCH62801.1 - 4.4 7.1 16.4 5.7 6.7 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myosin_head PF00063.16 CCH62802.1 - 1e-221 737.7 6.8 1.5e-221 737.1 4.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCH62802.1 - 4.1e-39 133.9 0.0 9.7e-39 132.7 0.0 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 CCH62802.1 - 5.3e-10 38.5 0.0 1.2e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCH62802.1 - 4.8e-07 29.2 0.0 1.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CCH62802.1 - 0.0029 17.7 0.0 0.0099 16.0 0.0 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 CCH62802.1 - 0.0046 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hpr_kinase_C PF07475.7 CCH62802.1 - 0.026 13.8 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.22 CCH62802.1 - 0.028 14.6 0.0 0.098 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 CCH62802.1 - 0.029 13.4 0.3 0.11 11.6 0.0 2.0 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.1 CCH62802.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 CCH62802.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CCH62802.1 - 0.075 12.6 0.0 0.19 11.4 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_17 PF13207.1 CCH62802.1 - 0.077 13.8 0.0 0.28 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCH62802.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IQ PF00612.22 CCH62802.1 - 0.37 10.5 9.0 0.96 9.2 0.8 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif TFIIE_alpha PF02002.12 CCH62803.1 - 1.3e-33 114.6 0.2 5.2e-33 112.7 0.0 2.2 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 CCH62803.1 - 2.3e-11 42.7 0.7 8.3e-11 41.0 0.5 2.0 1 0 0 1 1 1 1 TFIIB zinc-binding DUF1759 PF03564.10 CCH62803.1 - 0.026 14.3 0.1 0.026 14.3 0.1 2.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1759) Malic_M PF03949.10 CCH62804.1 - 1.7e-68 230.9 0.0 2.4e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCH62804.1 - 2.3e-65 219.6 0.0 3.4e-65 219.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NIF PF03031.13 CCH62805.1 - 2.6e-50 170.1 0.1 3.7e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-C2H2 PF00096.21 CCH62807.1 - 2.7e-05 24.2 4.5 2.7e-05 24.2 3.1 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62807.1 - 0.00019 21.5 14.9 0.00019 21.5 2.6 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CCH62807.1 - 0.0024 17.9 5.4 0.0045 17.0 3.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCH62807.1 - 0.079 13.0 8.5 0.36 10.9 0.6 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 CCH62807.1 - 8.6 6.8 16.5 2.9 8.3 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-RING_2 PF13639.1 CCH62808.1 - 9.8e-11 41.3 5.5 1.9e-10 40.3 3.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCH62808.1 - 4.9e-08 32.9 5.8 9.2e-08 32.0 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCH62808.1 - 6.4e-08 32.1 4.1 1.1e-07 31.4 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCH62808.1 - 5.5e-07 29.1 3.7 1e-06 28.2 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH62808.1 - 1.7e-05 24.7 2.4 1.7e-05 24.7 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH62808.1 - 3.4e-05 23.4 7.4 6.5e-05 22.5 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCH62808.1 - 0.0017 18.1 2.0 0.0039 17.0 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 CCH62808.1 - 0.026 14.3 1.9 0.057 13.2 0.2 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCH62808.1 - 0.045 13.4 1.6 0.14 11.9 0.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 CCH62808.1 - 0.047 13.6 6.5 0.19 11.7 4.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain DUF1706 PF08020.6 CCH62808.1 - 0.059 12.8 0.7 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1706) zf-P11 PF03854.9 CCH62808.1 - 1.2 8.6 6.1 0.28 10.6 1.6 1.8 2 0 0 2 2 2 0 P-11 zinc finger RINGv PF12906.2 CCH62808.1 - 7.1 6.7 7.4 21 5.2 5.0 1.9 1 1 0 1 1 1 0 RING-variant domain Pribosyl_synth PF14572.1 CCH62809.1 - 1.6e-40 138.8 2.7 8.5e-35 120.1 1.2 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCH62809.1 - 6.8e-40 135.4 0.2 7.6e-38 128.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCH62809.1 - 8.6e-12 44.8 1.2 2e-11 43.6 0.8 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCH62809.1 - 0.0051 16.0 0.1 0.0097 15.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 CCH62809.1 - 0.039 13.6 1.2 0.094 12.4 0.8 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C Form_Nir_trans PF01226.12 CCH62811.1 - 5.2e-57 192.6 17.9 6.6e-57 192.2 12.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Cyt-b5 PF00173.23 CCH62812.1 - 1.6e-18 66.2 0.0 2.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2216 PF10226.4 CCH62812.1 - 0.092 12.2 0.7 0.15 11.5 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) UDPGP PF01704.13 CCH62813.1 - 2.2e-190 632.6 1.8 2.7e-190 632.3 1.3 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 CCH62813.1 - 0.014 13.9 0.0 0.54 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4301) Opi1 PF08618.5 CCH62814.1 - 7.5e-20 71.2 23.0 2.5e-12 46.4 9.1 4.4 1 1 1 2 2 2 2 Transcription factor Opi1 Snf7 PF03357.16 CCH62815.1 - 1.6e-32 112.2 19.2 1.6e-32 112.2 13.3 1.9 2 0 0 2 2 2 1 Snf7 Peptidase_C3 PF00548.15 CCH62815.1 - 0.023 14.5 0.9 0.038 13.7 0.6 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) PAS_7 PF12860.2 CCH62815.1 - 0.026 14.5 3.8 1.7 8.6 0.1 2.7 1 1 2 3 3 3 0 PAS fold Eno-Rase_FAD_bd PF07055.7 CCH62815.1 - 0.064 13.2 3.0 0.078 12.9 1.1 2.0 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Tau95 PF09734.4 CCH62815.1 - 0.37 10.0 2.9 0.48 9.7 2.0 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DUF489 PF04356.7 CCH62815.1 - 0.44 10.1 10.0 0.24 10.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) CLU PF13236.1 CCH62816.1 - 7.6e-68 228.2 0.2 7.6e-68 228.2 0.2 2.1 3 0 0 3 3 3 1 Clustered mitochondria eIF3_p135 PF12807.2 CCH62816.1 - 3.7e-31 108.3 11.9 1.6e-23 83.5 0.0 4.5 4 2 1 5 5 5 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CCH62816.1 - 1.2e-14 54.1 1.5 8.8e-14 51.4 0.3 3.1 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CCH62816.1 - 6.6e-07 29.1 0.1 0.017 15.0 0.0 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCH62816.1 - 0.13 12.2 0.0 2.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SecE PF00584.15 CCH62817.1 - 0.003 17.0 0.4 0.003 17.0 0.3 2.6 2 0 0 2 2 2 1 SecE/Sec61-gamma subunits of protein translocation complex GTP_EFTU PF00009.22 CCH62818.1 - 4.7e-23 81.6 0.1 4.7e-23 81.6 0.1 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CCH62818.1 - 4e-05 23.6 0.0 0.00014 21.8 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 AAA_29 PF13555.1 CCH62818.1 - 0.00057 19.3 0.2 0.0033 16.9 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 CCH62818.1 - 0.0026 16.7 2.4 0.0041 16.0 0.1 2.4 2 1 1 3 3 3 1 Type II/IV secretion system protein AAA_17 PF13207.1 CCH62818.1 - 0.0026 18.5 0.1 0.0097 16.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain DUF87 PF01935.12 CCH62818.1 - 0.0028 17.5 0.0 0.0028 17.5 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CCH62818.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_18 PF13238.1 CCH62818.1 - 0.013 15.8 0.5 0.05 13.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CCH62818.1 - 0.023 14.6 2.1 0.082 12.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 CCH62818.1 - 0.03 14.1 0.1 0.097 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 CCH62818.1 - 0.043 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCH62818.1 - 0.05 13.8 0.1 0.05 13.8 0.1 3.3 2 2 1 3 3 2 0 ABC transporter NACHT PF05729.7 CCH62818.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Miro PF08477.8 CCH62818.1 - 0.071 13.6 3.1 0.086 13.3 0.0 2.9 3 1 0 3 3 2 0 Miro-like protein AAA_16 PF13191.1 CCH62818.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 CCH62818.1 - 0.35 11.1 0.1 0.35 11.1 0.0 4.2 3 2 0 3 3 2 0 AAA domain HA2 PF04408.18 CCH62819.1 - 1.7e-24 85.7 0.0 5.4e-24 84.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCH62819.1 - 1.3e-18 66.8 0.0 5.6e-18 64.8 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCH62819.1 - 6e-14 51.6 0.0 2.1e-13 49.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH62819.1 - 2.8e-09 36.6 0.2 6.2e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCH62819.1 - 2.1e-07 31.1 0.1 7.7e-07 29.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCH62819.1 - 7.3e-05 22.4 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH62819.1 - 0.00055 19.6 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CCH62819.1 - 0.00081 19.2 0.1 0.00081 19.2 0.1 3.9 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 CCH62819.1 - 0.0013 18.5 1.8 0.037 13.9 0.8 3.3 2 1 0 2 2 1 1 AAA domain DUF2075 PF09848.4 CCH62819.1 - 0.0018 17.3 0.0 0.0039 16.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 CCH62819.1 - 0.0037 16.9 0.1 1.1 8.8 0.0 3.0 2 1 1 3 3 3 1 Helicase Miro PF08477.8 CCH62819.1 - 0.0083 16.6 0.3 0.21 12.0 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein IstB_IS21 PF01695.12 CCH62819.1 - 0.0094 15.3 0.0 3.9 6.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein T2SE PF00437.15 CCH62819.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 CCH62819.1 - 0.033 13.6 0.2 0.08 12.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 CCH62819.1 - 0.085 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_25 PF13481.1 CCH62819.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3336 PF11815.3 CCH62820.1 - 3.1e-35 120.8 6.3 9.7e-35 119.2 4.4 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCH62820.1 - 1.7e-28 99.9 0.2 7.5e-28 97.8 0.0 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase Abhydrolase_6 PF12697.2 CCH62822.1 - 1.8e-21 77.1 0.0 2.4e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCH62822.1 - 9.6e-09 35.1 0.0 3.1e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCH62822.1 - 6.2e-06 26.0 0.0 5e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCH62822.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 CCH62822.1 - 0.0076 15.6 0.0 0.52 9.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 CCH62822.1 - 0.051 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Helicase_C_3 PF13625.1 CCH62823.1 - 1.4e-24 86.2 0.0 3.8e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCH62823.1 - 4.3e-14 52.7 2.8 9.8e-14 51.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCH62823.1 - 2.2e-12 46.3 0.0 4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCH62823.1 - 1.2e-10 41.1 0.0 3.2e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH62823.1 - 3.1e-07 30.0 0.0 6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 CCH62823.1 - 0.042 13.1 0.0 0.086 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Ndc80_HEC PF03801.8 CCH62824.1 - 6.8e-52 175.1 0.5 3.7e-51 172.7 0.2 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family HlyD PF00529.15 CCH62824.1 - 3.7 6.7 12.9 1.2 8.4 1.0 2.5 2 0 0 2 2 2 0 HlyD family secretion protein Pantoate_ligase PF02569.10 CCH62825.1 - 5.1e-103 343.6 0.0 5.7e-103 343.5 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_syn PF06574.7 CCH62825.1 - 0.016 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 FAD synthetase HATPase_c PF02518.21 CCH62826.1 - 3.1e-28 97.6 0.4 1e-26 92.8 0.3 2.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCH62826.1 - 2e-27 95.4 0.1 4.4e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCH62826.1 - 2.8e-10 40.0 0.1 7.1e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 CCH62826.1 - 1.7e-05 24.9 0.4 0.08 13.1 0.1 2.6 2 0 0 2 2 2 2 HAMP domain TFR_dimer PF04253.10 CCH62827.1 - 0.074 12.6 1.0 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Myb_DNA-bind_6 PF13921.1 CCH62828.1 - 1.2e-26 92.5 4.9 5.1e-10 39.3 0.4 3.7 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCH62828.1 - 7.9e-25 86.6 9.2 3.2e-11 43.0 0.1 4.0 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CCH62828.1 - 0.0041 16.9 4.2 1.5 8.7 0.2 3.3 2 1 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1748 PF08520.5 CCH62829.1 - 3.9e-31 106.5 0.0 4.2e-31 106.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) G10 PF01125.12 CCH62830.1 - 2.6 7.6 10.3 0.16 11.5 0.2 2.7 3 0 0 3 3 3 0 G10 protein GalP_UDP_transf PF01087.17 CCH62831.1 - 4.2e-65 219.2 0.1 5.8e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCH62831.1 - 2.8e-64 215.6 0.5 2.8e-64 215.6 0.3 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CCH62831.1 - 0.013 15.9 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 HIT domain WG_beta_rep PF14903.1 CCH62831.1 - 0.069 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 WG containing repeat Aldose_epim PF01263.15 CCH62832.1 - 1.5e-77 260.6 0.3 2.3e-77 260.0 0.2 1.3 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 CCH62832.1 - 6.5e-54 182.8 0.0 1.8e-53 181.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CCH62832.1 - 2e-23 82.0 0.2 4.9e-23 80.8 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 CCH62832.1 - 1.6e-19 69.9 0.0 1.2e-17 63.7 0.0 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CCH62832.1 - 1.9e-17 62.8 0.0 1.4e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCH62832.1 - 1.2e-11 44.0 0.0 1.9e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 CCH62832.1 - 1.3e-10 40.6 0.0 3.6e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCH62832.1 - 3.1e-09 36.9 0.0 4.9e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCH62832.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCH62832.1 - 1.9e-07 31.2 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCH62832.1 - 0.0041 16.4 0.1 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family GalKase_gal_bdg PF10509.4 CCH62833.1 - 2.6e-22 77.8 0.0 9.4e-22 76.0 0.0 1.9 1 1 1 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCH62833.1 - 6.3e-15 54.9 0.1 1.4e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCH62833.1 - 1e-12 48.0 0.0 2.4e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal ABC2_membrane PF01061.19 CCH62834.1 - 2.7e-63 212.9 70.0 2.1e-38 131.6 10.4 3.0 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCH62834.1 - 2.6e-36 124.9 0.0 5.1e-17 62.4 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 CCH62834.1 - 1.1e-33 114.9 10.3 9.6e-31 105.5 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 CCH62834.1 - 2.9e-13 49.6 6.9 2.9e-13 49.6 4.8 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein ABC_trans_N PF14510.1 CCH62834.1 - 1.1e-09 38.2 0.0 3.5e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CCH62834.1 - 4.8e-06 25.8 0.0 0.00012 21.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCH62834.1 - 6.7e-06 25.6 0.0 0.0065 15.8 0.0 3.2 4 0 0 4 4 4 1 AAA domain cobW PF02492.14 CCH62834.1 - 9.1e-05 21.9 1.0 0.0012 18.3 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 CCH62834.1 - 0.00022 21.2 0.2 0.0092 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CCH62834.1 - 0.00023 20.6 0.1 0.066 12.7 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCH62834.1 - 0.0015 18.6 0.5 0.019 15.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCH62834.1 - 0.0017 17.8 0.1 3.6 7.0 0.0 3.1 3 0 0 3 3 3 2 FtsK/SpoIIIE family UPF0079 PF02367.12 CCH62834.1 - 0.0033 17.0 1.2 0.071 12.7 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 CCH62834.1 - 0.0034 16.6 0.0 0.6 9.2 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CCH62834.1 - 0.0091 16.3 1.0 0.067 13.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 CCH62834.1 - 0.0091 15.8 0.8 0.077 12.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 CCH62834.1 - 0.02 15.4 0.0 0.39 11.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 CCH62834.1 - 0.021 14.4 0.3 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CCH62834.1 - 0.022 14.6 0.0 0.32 10.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CCH62834.1 - 0.038 13.4 0.4 0.81 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_17 PF13207.1 CCH62834.1 - 0.053 14.3 0.0 0.45 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CCH62834.1 - 0.085 11.6 0.2 9 4.9 0.1 2.2 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 CCH62834.1 - 0.089 12.4 0.6 0.42 10.2 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 CCH62834.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCH62834.1 - 0.13 12.1 0.5 1.2 8.9 0.0 2.6 3 0 0 3 3 2 0 AAA domain Macro PF01661.16 CCH62835.1 - 3.4e-25 88.2 0.0 6.3e-25 87.3 0.0 1.4 1 1 0 1 1 1 1 Macro domain NRDE PF05742.7 CCH62835.1 - 0.021 14.1 0.0 0.33 10.2 0.0 2.0 1 1 1 2 2 2 0 NRDE protein SCO1-SenC PF02630.9 CCH62836.1 - 2.1e-58 196.7 2.4 3.5e-58 196.0 1.7 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CCH62836.1 - 0.00071 19.2 0.5 0.018 14.7 0.3 2.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCH62836.1 - 0.075 12.5 0.1 0.64 9.5 0.1 2.1 1 1 0 1 1 1 0 Redoxin EF-hand_7 PF13499.1 CCH62836.1 - 3.2 7.9 5.5 3.8 7.7 1.5 2.7 2 1 0 2 2 2 0 EF-hand domain pair EmrE PF13536.1 CCH62837.1 - 0.0022 18.2 0.7 0.0022 18.2 0.5 3.5 4 0 0 4 4 4 2 Multidrug resistance efflux transporter FixQ PF05545.6 CCH62837.1 - 0.46 10.1 0.0 0.46 10.1 0.0 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Pkinase PF00069.20 CCH62838.1 - 9.3e-66 221.6 0.1 2.2e-65 220.4 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62838.1 - 1.1e-29 103.2 0.1 9.8e-28 96.9 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCH62838.1 - 0.0022 18.4 1.6 0.0095 16.4 1.1 2.1 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCH62838.1 - 0.0047 15.9 0.0 0.045 12.6 0.0 2.3 3 0 0 3 3 3 1 Kinase-like DASH_Dad1 PF08649.5 CCH62839.1 - 9.9e-22 76.4 0.4 1.2e-21 76.1 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 PilJ PF13675.1 CCH62839.1 - 0.0092 16.2 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 Type IV pili methyl-accepting chemotaxis transducer N-term GCR1_C PF12550.3 CCH62839.1 - 0.037 13.9 0.1 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes G-alpha PF00503.15 CCH62839.1 - 0.068 11.8 0.1 0.07 11.8 0.1 1.0 1 0 0 1 1 1 0 G-protein alpha subunit IPK PF03770.11 CCH62840.1 - 3.1e-47 160.7 0.1 3.1e-47 160.7 0.0 3.3 4 0 0 4 4 4 1 Inositol polyphosphate kinase Fig1 PF12351.3 CCH62841.1 - 4.6e-44 150.5 5.3 4.6e-44 150.5 3.6 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 MARVEL PF01284.18 CCH62841.1 - 0.35 10.6 12.2 2.9 7.7 8.5 2.2 1 1 0 1 1 1 0 Membrane-associating domain Acyl_transf_3 PF01757.17 CCH62841.1 - 3.7 6.2 14.3 22 3.7 9.9 1.9 1 1 0 1 1 1 0 Acyltransferase family AMP-binding PF00501.23 CCH62842.1 - 1.1e-21 76.7 0.0 6.8e-10 37.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Acyltransferase PF01553.16 CCH62843.1 - 2.7e-28 98.0 0.1 5.9e-28 96.9 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase DEAD PF00270.24 CCH62844.1 - 4.7e-42 143.3 2.2 4.7e-42 143.3 1.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH62844.1 - 7.3e-28 96.2 0.8 9.2e-27 92.7 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCH62844.1 - 5.9e-05 22.7 0.1 0.00022 20.8 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCH62844.1 - 0.00017 21.7 0.2 0.00065 19.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 CCH62844.1 - 0.0013 17.8 0.1 0.0053 15.8 0.0 2.1 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 CCH62844.1 - 0.0029 17.2 0.1 0.0055 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 CCH62844.1 - 0.003 17.2 0.0 0.0067 16.0 0.0 1.6 1 0 0 1 1 1 1 Helicase ResIII PF04851.10 CCH62844.1 - 0.006 16.4 0.3 0.017 14.9 0.2 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CCH62844.1 - 0.0089 15.2 3.9 0.036 13.2 2.7 2.0 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.16 CCH62844.1 - 0.016 14.5 0.2 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain CobA_CobO_BtuR PF02572.10 CCH62844.1 - 0.045 13.3 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.9 CCH62844.1 - 0.048 13.4 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain PMSI1 PF15322.1 CCH62845.1 - 0.16 10.9 7.6 0.37 9.8 5.3 1.6 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF1752 PF08550.5 CCH62846.1 - 0.0074 15.8 0.2 0.017 14.6 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Fungal_trans_2 PF11951.3 CCH62847.1 - 4.1e-18 65.1 1.3 1.1e-17 63.7 0.9 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCH62847.1 - 4e-06 26.6 12.6 6.8e-06 25.8 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.7 CCH62848.1 - 3.3e-30 105.1 1.5 3.3e-30 105.1 1.1 2.1 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.1 CCH62848.1 - 1.1e-09 38.4 0.0 0.016 15.5 0.0 5.7 3 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62848.1 - 3e-08 33.5 0.0 0.34 11.6 0.0 6.8 7 1 1 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 CCH62848.1 - 0.00016 21.7 1.5 0.41 10.8 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCH62848.1 - 0.00058 19.8 0.1 1.6 9.1 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62848.1 - 0.00059 19.5 0.1 1.6 8.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCH62848.1 - 0.00081 18.9 0.1 0.041 13.5 0.0 3.5 2 1 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 CCH62848.1 - 0.00091 19.8 0.0 0.082 13.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62848.1 - 0.001 18.6 8.2 9.1 6.3 0.1 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat CYSTM PF12734.2 CCH62849.1 - 1.3e-07 31.6 7.2 1.3e-07 31.6 5.0 2.8 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance DUF3317 PF11779.3 CCH62851.1 - 1.5 8.3 7.3 1.9 8.0 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Pkinase PF00069.20 CCH62852.1 - 6.6e-34 117.2 0.6 1.3e-33 116.2 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62852.1 - 3.7e-23 81.9 0.1 5.9e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCH62852.1 - 0.00099 18.1 0.1 0.0037 16.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like FtsJ PF01728.14 CCH62853.1 - 4.8e-64 215.6 0.0 7.6e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ribosomal_S10 PF00338.17 CCH62854.1 - 3e-25 87.8 0.0 8.3e-25 86.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.1 CCH62855.1 - 2.2e-11 43.4 7.1 4.2e-11 42.4 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCH62855.1 - 2.6e-09 37.0 5.6 5e-09 36.1 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCH62855.1 - 2.5e-07 30.4 4.1 6.7e-07 29.0 2.6 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CCH62855.1 - 9e-05 22.4 8.9 0.00019 21.3 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCH62855.1 - 0.00021 20.8 8.3 0.00021 20.8 5.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH62855.1 - 0.00023 20.8 6.2 0.00052 19.6 4.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCH62855.1 - 0.0017 17.9 6.8 0.0017 17.9 3.8 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCH62855.1 - 0.061 13.0 0.4 0.061 13.0 0.3 2.7 2 1 1 3 3 3 0 RING-type zinc-finger RINGv PF12906.2 CCH62855.1 - 0.072 13.1 5.9 0.17 11.9 4.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 CCH62855.1 - 0.072 12.5 9.4 0.37 10.2 6.6 2.0 1 1 1 2 2 2 0 P-11 zinc finger RRN7 PF11781.3 CCH62855.1 - 0.084 12.3 1.0 8 6.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2217 PF10265.4 CCH62855.1 - 0.089 11.5 2.6 0.11 11.2 1.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SGS PF05002.10 CCH62855.1 - 0.095 12.4 1.3 5.5 6.8 0.0 2.3 1 1 1 2 2 2 0 SGS domain FANCL_C PF11793.3 CCH62855.1 - 0.099 12.6 6.5 0.78 9.7 4.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 CCH62855.1 - 0.57 9.7 5.8 1.5 8.3 4.0 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CCH62855.1 - 5.3 6.9 8.8 40 4.1 6.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C2H2_4 PF13894.1 CCH62856.1 - 3.3e-07 30.1 14.4 0.0009 19.4 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62856.1 - 4e-06 26.8 2.1 4e-06 26.8 1.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCH62856.1 - 7.8e-05 22.7 16.6 0.0017 18.6 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CCH62856.1 - 0.015 15.4 1.0 0.015 15.4 0.7 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING-like PF08746.6 CCH62856.1 - 0.024 14.6 2.8 0.024 14.6 2.0 1.7 2 0 0 2 2 2 0 RING-like domain zf-BED PF02892.10 CCH62856.1 - 7.6 6.3 18.6 32 4.3 5.9 2.9 1 1 1 2 2 2 0 BED zinc finger TFIIS_C PF01096.13 CCH62857.1 - 4e-22 77.5 1.2 4e-22 77.5 0.8 2.8 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCH62857.1 - 1.4e-11 43.9 3.7 1.6e-11 43.6 0.4 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CCH62857.1 - 0.0018 18.0 4.3 0.34 10.7 0.3 2.5 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Elf1 PF05129.8 CCH62857.1 - 0.0019 17.8 3.6 0.016 14.8 0.1 2.3 2 1 0 2 2 2 1 Transcription elongation factor Elf1 like DUF2387 PF09526.5 CCH62857.1 - 0.0023 17.8 3.5 0.031 14.2 0.1 2.3 2 1 0 2 2 2 1 Probable metal-binding protein (DUF2387) zinc_ribbon_5 PF13719.1 CCH62857.1 - 0.085 12.4 8.8 1.8 8.1 0.2 3.6 3 1 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.7 CCH62857.1 - 0.16 11.9 4.7 1.4 8.9 0.2 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain Baculo_LEF5_C PF11792.3 CCH62857.1 - 0.16 11.3 3.6 0.35 10.2 0.1 2.7 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 CCH62857.1 - 0.2 11.5 6.0 1.1 9.1 0.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon Terminase_GpA PF05876.7 CCH62857.1 - 0.27 9.5 1.3 0.74 8.0 0.9 1.8 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) PhnA_Zn_Ribbon PF08274.7 CCH62857.1 - 0.3 10.8 5.6 4.4 7.1 0.2 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF2296 PF10058.4 CCH62857.1 - 0.34 10.6 5.2 8.1 6.2 0.1 2.9 2 1 1 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Desulfoferrod_N PF06397.7 CCH62857.1 - 0.38 10.1 0.2 0.38 10.1 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Lar_restr_allev PF14354.1 CCH62857.1 - 0.54 10.6 5.4 5.6 7.3 0.1 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar IBR PF01485.16 CCH62857.1 - 0.92 9.4 9.3 0.79 9.6 0.3 2.9 2 1 1 3 3 3 0 IBR domain zf-RING_3 PF14369.1 CCH62857.1 - 3.8 7.5 6.3 17 5.5 0.9 3.3 3 1 0 3 3 3 0 zinc-finger zf-piccolo PF05715.8 CCH62857.1 - 3.8 7.5 9.6 0.15 12.0 1.3 2.4 3 0 0 3 3 3 0 Piccolo Zn-finger Ogr_Delta PF04606.7 CCH62857.1 - 4.8 6.9 7.5 17 5.1 0.2 3.2 3 1 0 3 3 3 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.1 CCH62857.1 - 8.9 6.8 13.3 12 6.3 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double domain AA_permease PF00324.16 CCH62858.1 - 2.6e-116 388.7 40.8 3.1e-116 388.5 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH62858.1 - 1.7e-31 109.2 42.4 2.3e-31 108.8 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCH62859.1 - 9.2e-117 390.2 32.4 1.2e-116 389.9 22.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCH62859.1 - 3.7e-37 127.8 31.7 4.6e-37 127.5 21.9 1.1 1 0 0 1 1 1 1 Amino acid permease ROK PF00480.15 CCH62859.1 - 0.045 13.5 0.4 0.1 12.4 0.2 1.6 2 0 0 2 2 2 0 ROK family Thioredoxin PF00085.15 CCH62860.1 - 0.00015 21.3 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCH62860.1 - 0.0031 17.6 0.0 0.0064 16.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_6 PF13848.1 CCH62860.1 - 0.01 15.6 0.5 0.055 13.2 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain MSP1_C PF07462.6 CCH62860.1 - 0.029 12.7 0.2 0.031 12.6 0.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Thioredoxin_3 PF13192.1 CCH62860.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_8 PF13905.1 CCH62860.1 - 0.13 12.3 0.7 1.5 8.9 0.2 2.8 2 1 0 2 2 2 0 Thioredoxin-like His_Phos_1 PF00300.17 CCH62861.1 - 7.1e-38 130.1 0.1 1e-37 129.6 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TIM PF00121.13 CCH62862.1 - 2.8e-89 298.3 1.1 3.2e-89 298.1 0.8 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase MreB_Mbl PF06723.8 CCH62862.1 - 0.011 14.4 0.8 0.074 11.6 0.0 2.2 2 1 0 2 2 2 0 MreB/Mbl protein Alg14 PF08660.6 CCH62863.1 - 1.8e-47 161.5 0.3 2.5e-47 161.0 0.2 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Pigment_DH PF06324.6 CCH62863.1 - 0.092 12.0 2.8 0.17 11.1 1.9 1.5 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) DDE_Tnp_ISL3 PF01610.12 CCH62863.1 - 0.1 12.1 0.9 0.13 11.7 0.6 1.1 1 0 0 1 1 1 0 Transposase zf-C2H2 PF00096.21 CCH62864.1 - 7.2e-09 35.4 11.9 0.00023 21.2 1.3 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62864.1 - 6.4e-05 23.0 9.1 0.019 15.2 0.8 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62864.1 - 0.00021 21.3 0.4 0.00021 21.3 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CCH62864.1 - 0.00055 20.0 3.3 0.29 11.3 0.4 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCH62864.1 - 1.3 9.2 7.5 1.2 9.3 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CCH62864.1 - 4.8 7.0 14.0 0.047 13.4 2.9 2.9 2 1 1 3 3 3 0 BED zinc finger zf-DBF PF07535.7 CCH62865.1 - 1.1e-07 31.3 1.7 1.1e-07 31.3 1.1 2.6 2 0 0 2 2 2 1 DBF zinc finger Recep_L_domain PF01030.19 CCH62866.1 - 5.1e-08 32.8 6.6 0.0021 18.0 0.2 4.4 1 1 3 4 4 4 3 Receptor L domain LRR_9 PF14580.1 CCH62866.1 - 0.019 14.5 0.2 0.054 13.0 0.0 1.8 1 1 1 2 2 2 0 Leucine-rich repeat Macoilin PF09726.4 CCH62866.1 - 0.16 10.1 17.5 0.26 9.5 12.2 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4339 PF14237.1 CCH62866.1 - 0.16 11.5 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) SSFA2_C PF14723.1 CCH62866.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.2 2 1 0 2 2 2 0 Sperm-specific antigen 2 C-terminus DUF2464 PF10240.4 CCH62866.1 - 0.61 9.3 9.1 1.3 8.3 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) AAA PF00004.24 CCH62867.1 - 1e-52 177.7 1.0 1.4e-38 132.0 0.0 3.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCH62867.1 - 1.5e-10 40.9 0.0 3.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 CCH62867.1 - 1.5e-09 38.0 1.4 0.00064 19.8 0.2 3.9 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCH62867.1 - 4e-08 32.3 0.1 0.002 16.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 CCH62867.1 - 5.6e-08 33.6 0.2 0.015 16.1 0.2 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCH62867.1 - 1.5e-07 31.5 0.0 0.0068 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCH62867.1 - 2.7e-07 30.3 0.0 0.0031 17.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCH62867.1 - 4.7e-07 29.4 0.1 0.0049 16.5 0.1 2.4 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 CCH62867.1 - 5.6e-07 29.0 0.6 1.8e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.1 CCH62867.1 - 9.3e-07 28.8 0.0 0.0097 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCH62867.1 - 1.1e-06 28.6 0.0 0.0011 18.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CCH62867.1 - 1.7e-06 28.3 1.4 0.027 14.7 0.0 3.8 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CCH62867.1 - 6.3e-06 25.7 0.0 0.032 13.6 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCH62867.1 - 1.2e-05 24.6 5.3 0.0021 17.2 0.0 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCH62867.1 - 1.3e-05 25.3 0.0 0.13 12.4 0.0 3.0 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 CCH62867.1 - 2e-05 23.7 0.1 0.074 12.0 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 CCH62867.1 - 2.3e-05 23.9 0.0 0.065 12.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 CCH62867.1 - 7.2e-05 22.1 0.0 0.27 10.4 0.0 2.9 3 0 0 3 3 3 2 PhoH-like protein ABC_tran PF00005.22 CCH62867.1 - 0.00014 22.1 0.3 0.056 13.7 0.1 2.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 CCH62867.1 - 0.00023 20.8 2.4 0.12 11.9 0.0 3.4 4 0 0 4 4 3 1 NACHT domain ResIII PF04851.10 CCH62867.1 - 0.00038 20.3 0.2 0.42 10.4 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CCH62867.1 - 0.00048 19.7 0.4 0.4 10.2 0.2 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCH62867.1 - 0.00093 18.1 0.0 1.4 7.7 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 CCH62867.1 - 0.0012 17.9 0.0 0.96 8.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 CCH62867.1 - 0.0015 17.9 3.8 1.7 8.0 0.1 3.9 2 2 2 4 4 4 1 AAA domain KaiC PF06745.8 CCH62867.1 - 0.0046 16.1 4.0 0.16 11.0 0.1 3.1 4 0 0 4 4 2 1 KaiC AAA_3 PF07726.6 CCH62867.1 - 0.0064 16.0 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCH62867.1 - 0.0087 15.0 0.0 0.15 10.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CCH62867.1 - 0.009 15.6 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 CCH62867.1 - 0.0093 15.4 0.9 18 4.7 0.0 3.9 2 2 1 4 4 4 0 DEAD/DEAH box helicase T2SE PF00437.15 CCH62867.1 - 0.018 13.9 0.0 3 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 CCH62867.1 - 0.026 14.1 0.1 4.6 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CCH62867.1 - 0.037 13.4 0.3 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 CCH62867.1 - 0.041 13.8 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCH62867.1 - 0.059 12.8 0.4 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.11 CCH62867.1 - 0.064 12.4 0.0 2.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Isopentenyl transferase Sigma54_activ_2 PF14532.1 CCH62867.1 - 0.087 12.8 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PRKCSH PF07915.8 CCH62869.1 - 5.5e-10 39.9 0.4 5.5e-10 39.9 0.2 4.6 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Bromodomain PF00439.20 CCH62870.1 - 7.4e-16 57.8 0.3 7.4e-16 57.8 0.2 2.8 4 0 0 4 4 4 1 Bromodomain Bromo_TP PF07524.8 CCH62870.1 - 1.5e-05 24.6 0.0 4.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated UQ_con PF00179.21 CCH62871.1 - 2.3e-51 172.9 0.0 2.6e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH62871.1 - 6.2e-05 22.7 0.0 7.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCH62871.1 - 0.00023 21.0 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CCH62871.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain CBF PF03914.12 CCH62872.1 - 2.8e-45 153.7 0.7 2.8e-45 153.7 0.5 3.6 3 1 1 4 4 4 1 CBF/Mak21 family TEA PF01285.13 CCH62873.1 - 7.5e-30 104.4 5.5 7.5e-30 104.4 3.8 3.0 2 1 0 3 3 3 1 TEA/ATTS domain family FTHFS PF01268.14 CCH62874.1 - 1.7e-233 775.6 0.1 2.3e-233 775.2 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCH62874.1 - 2.6e-66 221.6 0.5 4.8e-66 220.7 0.3 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCH62874.1 - 6.3e-35 119.7 1.0 1.7e-34 118.3 0.7 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 CCH62874.1 - 0.011 15.6 1.4 0.13 12.1 0.7 2.6 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L19e PF01280.15 CCH62875.1 - 3.5e-59 198.8 9.7 3.5e-59 198.8 6.7 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF3527 PF12043.3 CCH62875.1 - 0.0063 16.0 1.0 0.0076 15.8 0.5 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3527) DUF2423 PF10338.4 CCH62876.1 - 3e-17 62.2 1.1 3e-17 62.2 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) HSP20 PF00011.16 CCH62876.1 - 0.0043 16.8 0.5 0.0064 16.3 0.3 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Birna_VP3 PF01767.11 CCH62876.1 - 0.069 12.7 1.5 0.071 12.7 1.0 1.1 1 0 0 1 1 1 0 Birnavirus VP3 protein Ribosomal_L6e PF01159.14 CCH62876.1 - 3.3 7.9 6.3 2.3 8.4 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein L6e Elf1 PF05129.8 CCH62877.1 - 0.043 13.5 0.2 0.085 12.5 0.2 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CCH62877.1 - 0.058 13.2 2.9 0.24 11.2 2.0 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Cys_rich_KTR PF14205.1 CCH62877.1 - 0.14 11.5 2.0 0.48 9.9 0.4 2.3 2 1 0 2 2 2 0 Cysteine-rich KTR Ala_racemase_N PF01168.15 CCH62880.1 - 1.6e-39 135.6 0.0 1.8e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 CCH62881.1 - 2.2e-64 217.6 33.1 2.6e-64 217.4 22.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CCH62881.1 - 0.044 13.7 0.1 0.18 11.8 0.1 2.1 1 1 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain HMG_box PF00505.14 CCH62882.1 - 3.6e-25 88.0 0.6 5.6e-25 87.3 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCH62882.1 - 1.1e-19 70.5 0.6 1.7e-19 69.9 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CCH62882.1 - 0.00079 19.1 3.6 0.00094 18.9 2.2 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 CCH62882.1 - 0.053 13.7 0.1 0.17 12.0 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) RXT2_N PF08595.6 CCH62883.1 - 4.1e-30 104.5 5.3 4.1e-30 104.5 3.7 3.5 3 1 0 3 3 3 1 RXT2-like, N-terminal DUF3461 PF11944.3 CCH62883.1 - 0.017 14.9 0.8 0.04 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Membralin PF09746.4 CCH62883.1 - 0.42 9.5 2.6 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Tumour-associated protein Ret_tiss PF10044.4 CCH62883.1 - 0.52 10.8 3.7 22 5.6 0.5 3.0 1 1 1 2 2 2 0 Retinal tissue protein MBOAT PF03062.14 CCH62884.1 - 1.6e-39 135.9 48.7 7.7e-39 133.6 33.7 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family B-block_TFIIIC PF04182.7 CCH62885.1 - 0.03 14.1 0.2 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC DASH_Dad2 PF08654.5 CCH62885.1 - 5.6 7.0 9.5 3.1 7.8 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad2 WD40 PF00400.27 CCH62886.1 - 2.5e-62 204.6 12.5 1.3e-12 47.0 0.0 13.2 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.7 CCH62886.1 - 3e-27 94.7 0.0 5.1e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CCH62886.1 - 1.1e-09 38.3 3.9 0.0024 17.5 0.0 5.8 4 1 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCH62886.1 - 9.2e-08 30.6 7.2 0.1 10.7 0.0 5.4 2 2 3 5 5 5 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 CCH62886.1 - 0.00017 20.7 2.9 0.69 8.9 0.3 4.7 4 2 2 6 6 6 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 CCH62886.1 - 0.0012 18.3 0.6 0.064 12.6 0.1 3.1 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 CCH62886.1 - 0.0018 17.8 0.4 0.89 9.2 0.1 4.0 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 CCH62886.1 - 0.0027 16.5 0.1 0.29 9.8 0.0 3.6 3 1 1 4 4 4 1 Coatomer WD associated region Cytochrom_D1 PF02239.11 CCH62886.1 - 0.0059 14.9 0.3 0.14 10.3 0.0 3.0 3 1 0 3 3 3 1 Cytochrome D1 heme domain RAB3GAP2_N PF14655.1 CCH62886.1 - 0.023 13.7 0.0 0.055 12.4 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Apc4_WD40 PF12894.2 CCH62886.1 - 0.038 13.4 0.0 7.8 6.0 0.0 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.6 CCH62886.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain UPF0029 PF01205.14 CCH62888.1 - 4.2e-27 94.0 0.0 6.5e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CCH62888.1 - 4.4e-10 39.4 0.5 1.1e-09 38.1 0.3 1.7 1 1 0 1 1 1 1 RWD domain TPR_11 PF13414.1 CCH62889.1 - 1.8e-17 62.6 0.0 3.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CCH62889.1 - 2e-14 52.4 0.0 2.1e-06 27.0 0.0 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62889.1 - 5.5e-12 44.6 0.0 3e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62889.1 - 1.4e-07 30.7 0.9 0.00023 20.7 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCH62889.1 - 3.7e-07 29.9 0.0 0.003 17.4 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCH62889.1 - 7.1e-06 25.8 0.0 6.5e-05 22.8 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCH62889.1 - 1.2e-05 25.5 0.0 2.5e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCH62889.1 - 9.5e-05 22.7 0.0 0.34 11.6 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCH62889.1 - 0.00012 21.6 0.0 0.71 9.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CCH62889.1 - 0.00017 21.6 0.0 0.00044 20.3 0.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCH62889.1 - 0.0015 19.1 0.0 0.005 17.4 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.13 CCH62889.1 - 0.0054 16.5 0.1 4 7.4 0.0 2.3 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.4 CCH62889.1 - 0.0079 15.4 0.0 0.5 9.6 0.0 2.5 2 0 0 2 2 2 1 SHNi-TPR U3_assoc_6 PF08640.6 CCH62889.1 - 0.0094 15.6 0.3 0.015 15.0 0.2 1.3 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.1 CCH62889.1 - 0.0099 16.2 0.2 6.8 7.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCH62889.1 - 0.035 13.9 0.0 1.1 9.2 0.0 2.3 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat 4HB_MCP_1 PF12729.2 CCH62889.1 - 0.055 12.8 0.4 0.089 12.1 0.3 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TPR_9 PF13371.1 CCH62889.1 - 0.058 13.2 0.0 0.089 12.6 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat PH PF00169.24 CCH62890.1 - 8.2e-07 29.1 5.5 8.3e-07 29.1 0.2 3.5 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 CCH62890.1 - 0.0083 16.3 1.3 0.031 14.5 0.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain ANTH PF07651.11 CCH62891.1 - 5.6e-57 192.5 0.1 8.8e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 CCH62891.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 ENTH domain IncA PF04156.9 CCH62891.1 - 0.00015 21.4 2.6 0.00029 20.4 1.8 1.4 1 0 0 1 1 1 1 IncA protein Myosin_tail_1 PF01576.14 CCH62891.1 - 0.017 12.9 1.6 0.024 12.4 1.1 1.1 1 0 0 1 1 1 0 Myosin tail TPR_MLP1_2 PF07926.7 CCH62891.1 - 0.023 14.4 3.3 0.063 13.0 2.2 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF501 PF04417.7 CCH62891.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF745 PF05335.8 CCH62891.1 - 0.064 12.7 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF3552 PF12072.3 CCH62891.1 - 0.083 12.0 4.0 0.14 11.3 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ATG16 PF08614.6 CCH62891.1 - 0.26 11.0 6.6 0.63 9.8 4.6 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) G10 PF01125.12 CCH62892.1 - 1.7e-59 199.4 6.5 2e-59 199.3 4.5 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 CCH62893.1 - 1.5e-34 117.8 0.1 6.1e-34 115.9 0.1 2.1 1 0 0 1 1 1 1 Fork head domain Utp14 PF04615.8 CCH62893.1 - 0.98 7.5 27.6 2.6 6.1 0.2 2.3 2 0 0 2 2 2 0 Utp14 protein zf-C3HC4 PF00097.20 CCH62894.1 - 1.6e-10 40.4 10.3 1.6e-10 40.4 7.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCH62894.1 - 1.3e-09 37.9 14.4 6.6e-09 35.6 7.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCH62894.1 - 1.3e-07 31.3 12.0 6.7e-07 29.0 6.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCH62894.1 - 4.9e-07 29.3 11.1 7.8e-07 28.6 4.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCH62894.1 - 1.5e-06 27.9 9.5 1.5e-06 27.9 6.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCH62894.1 - 1.6e-06 27.7 13.6 2.9e-06 26.9 6.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CCH62894.1 - 1.8e-06 27.6 7.1 6e-06 25.9 3.4 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein SAP PF02037.22 CCH62894.1 - 1.6e-05 24.2 0.0 3.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_UBOX PF13445.1 CCH62894.1 - 5.4e-05 22.8 8.0 5.4e-05 22.8 5.6 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 CCH62894.1 - 0.003 17.6 2.9 0.003 17.6 2.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 CCH62894.1 - 0.0089 15.9 0.2 0.064 13.2 0.0 2.5 3 0 0 3 3 3 1 U-box domain zf-RING_4 PF14570.1 CCH62894.1 - 0.5 9.9 6.5 0.53 9.9 1.4 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Phos_pyr_kin PF08543.7 CCH62895.1 - 3.6e-10 39.4 0.0 5.1e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CCH62895.1 - 0.00035 19.8 0.0 0.00081 18.5 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Lipase_3 PF01764.20 CCH62896.1 - 3.3e-10 39.7 0.0 8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CCH62896.1 - 0.051 13.3 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 CCH62896.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pro_isomerase PF00160.16 CCH62897.1 - 3.2e-19 69.6 0.1 5.2e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 CCH62898.1 - 5.8e-63 212.4 0.0 2e-62 210.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH62898.1 - 3.3e-37 127.9 0.2 1.2e-26 93.3 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH62898.1 - 2.9e-05 23.1 1.5 0.0018 17.2 0.0 3.5 4 0 0 4 4 4 1 Kinase-like APH PF01636.18 CCH62898.1 - 0.14 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Metallophos PF00149.23 CCH62899.1 - 3.4e-41 140.8 1.4 5.5e-41 140.1 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UPF0113 PF03657.8 CCH62899.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0113) Chorismate_bind PF00425.13 CCH62900.1 - 1.8e-62 210.9 0.0 2.8e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CCH62900.1 - 2e-31 108.9 0.0 3.3e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CCH62900.1 - 1.8e-15 57.1 0.0 4.4e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CCH62900.1 - 9.8e-10 38.2 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Glucosamine_iso PF01182.15 CCH62901.1 - 6.3e-48 163.1 0.0 9.8e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase E_Pc_C PF06752.7 CCH62901.1 - 0.061 12.8 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PQ-loop PF04193.9 CCH62902.1 - 6.3e-20 70.4 11.9 1.1e-12 47.2 0.2 3.6 3 1 1 4 4 4 2 PQ loop repeat COX14 PF14880.1 CCH62902.1 - 0.027 14.1 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly HemY_N PF07219.8 CCH62903.1 - 0.026 14.0 0.9 6.9 6.2 0.1 3.6 2 1 1 3 3 3 0 HemY protein N-terminus PI31_Prot_C PF08577.6 CCH62904.1 - 8.1e-11 42.4 6.0 8.1e-11 42.4 4.2 2.2 2 0 0 2 2 2 1 PI31 proteasome regulator PP2C PF00481.16 CCH62905.1 - 4.9e-27 94.9 0.0 9.9e-26 90.6 0.0 2.6 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCH62905.1 - 0.0024 17.3 0.0 0.013 14.9 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C Cation_efflux PF01545.16 CCH62906.1 - 0.72 8.8 13.6 1.9 7.4 9.4 1.6 1 1 0 1 1 1 0 Cation efflux family F-box PF00646.28 CCH62907.1 - 0.00033 20.2 0.2 0.00092 18.8 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCH62907.1 - 0.00058 19.5 0.1 0.0017 18.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like PUF PF00806.14 CCH62908.1 - 4.5e-30 101.4 0.7 8e-05 21.9 0.0 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat RRM_1 PF00076.17 CCH62908.1 - 5.2e-06 26.0 0.0 1.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH62908.1 - 3.2e-05 23.7 0.0 9.1e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH62908.1 - 0.002 18.0 0.0 0.0077 16.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Anillin PF08174.6 CCH62909.1 - 8.7e-11 42.0 0.1 4e-10 39.8 0.1 2.2 1 0 0 1 1 1 1 Cell division protein anillin Ribosomal_L37ae PF01780.14 CCH62910.1 - 6e-40 135.0 8.8 6.7e-40 134.8 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1364 PF07102.7 CCH62910.1 - 0.00091 19.0 0.9 0.0011 18.7 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1364) Zn_Tnp_IS1595 PF12760.2 CCH62910.1 - 0.0017 18.1 2.8 0.0026 17.5 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CCH62910.1 - 0.0027 17.1 2.0 0.14 11.6 0.1 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain CarbpepA_inh PF02977.10 CCH62910.1 - 0.0052 16.3 0.6 0.0052 16.3 0.4 2.0 1 1 1 2 2 2 1 Carboxypeptidase A inhibitor Rep_fac-A_C PF08646.5 CCH62910.1 - 0.0053 16.4 0.5 0.006 16.2 0.3 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain zf-H2C2_2 PF13465.1 CCH62910.1 - 0.011 16.0 0.5 0.71 10.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 CCH62910.1 - 0.012 14.8 0.6 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Sgf11 PF08209.6 CCH62910.1 - 0.016 14.5 0.5 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C4_ClpX PF06689.8 CCH62910.1 - 0.05 13.1 2.2 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 ClpX C4-type zinc finger OrfB_Zn_ribbon PF07282.6 CCH62910.1 - 0.053 13.1 2.5 0.085 12.5 1.4 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.1 CCH62910.1 - 0.087 12.3 1.2 0.86 9.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 CCH62910.1 - 0.092 12.4 1.8 0.14 11.8 1.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Sec23_Sec24 PF04810.10 CCH62910.1 - 0.097 12.2 3.4 2.3 7.8 0.0 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger DZR PF12773.2 CCH62910.1 - 0.21 11.4 1.7 0.51 10.1 1.2 1.6 1 1 1 2 2 2 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.1 CCH62910.1 - 0.24 11.8 2.2 0.47 10.8 1.5 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.11 CCH62910.1 - 0.25 11.4 1.9 0.63 10.2 1.3 1.7 1 1 0 1 1 1 0 C1 domain Nudix_N_2 PF14803.1 CCH62910.1 - 0.3 10.7 1.7 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Nudix N-terminal zf-BED PF02892.10 CCH62910.1 - 0.45 10.3 5.0 6.1 6.6 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger PHD PF00628.24 CCH62910.1 - 0.75 9.5 3.9 7.6 6.3 0.4 2.1 1 1 1 2 2 2 0 PHD-finger zf-C2H2 PF00096.21 CCH62910.1 - 1.2 9.6 3.7 5.5 7.5 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Prok-RING_2 PF14445.1 CCH62910.1 - 2.6 8.0 5.0 15 5.6 3.4 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Prim_Zn_Ribbon PF08273.7 CCH62910.1 - 3 7.9 5.1 18 5.4 3.5 2.0 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Zn_clus PF00172.13 CCH62911.1 - 8.4e-08 31.9 10.4 1.4e-07 31.2 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Svf1 PF08622.5 CCH62912.1 - 2.4e-93 312.6 3.0 3e-93 312.3 2.0 1.1 1 0 0 1 1 1 1 Svf1-like Tox-ART-HYE1 PF15634.1 CCH62912.1 - 0.013 14.5 0.1 0.085 11.8 0.1 2.1 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase YodL PF14191.1 CCH62912.1 - 0.05 14.1 0.3 17 5.9 0.1 2.7 2 0 0 2 2 2 0 YodL-like WD40 PF00400.27 CCH62913.1 - 2.6e-59 195.1 24.5 4.6e-09 35.8 0.1 11.4 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 CCH62913.1 - 1.5e-45 154.2 0.1 2.7e-45 153.4 0.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CCH62913.1 - 7.1e-05 21.1 2.2 0.31 9.1 0.1 4.5 3 2 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCH62913.1 - 0.029 12.6 0.1 6.7 4.8 0.0 2.6 2 1 0 2 2 2 0 Cytochrome D1 heme domain Rsa3 PF14615.1 CCH62914.1 - 3.9e-19 67.6 0.1 6.3e-19 67.0 0.1 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 FliE PF02049.13 CCH62914.1 - 0.075 13.0 9.4 0.052 13.5 1.6 2.6 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Daxx PF03344.10 CCH62914.1 - 0.44 8.9 18.9 0.51 8.7 13.1 1.0 1 0 0 1 1 1 0 Daxx Family VIT1 PF01988.14 CCH62915.1 - 2.8e-55 187.0 0.6 3.4e-55 186.8 0.4 1.1 1 0 0 1 1 1 1 VIT family DUF1517 PF07466.6 CCH62915.1 - 0.023 13.6 0.7 0.039 12.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Histone PF00125.19 CCH62916.1 - 1.4e-21 76.4 0.3 1.9e-21 75.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH62916.1 - 6.8e-06 26.0 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCH62916.1 - 0.0013 19.0 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CCH62916.1 - 0.013 14.2 2.9 0.015 13.9 2.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF869 PF05911.6 CCH62916.1 - 0.088 11.0 2.5 0.093 10.9 1.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) RNA_pol_Rpb2_1 PF04563.10 CCH62916.1 - 1 8.2 3.6 5.6 5.8 0.6 2.0 1 1 1 2 2 2 0 RNA polymerase beta subunit Histone PF00125.19 CCH62917.1 - 9.4e-26 89.7 0.0 1.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCH62917.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Orthopox_C10L PF07020.6 CCH62918.1 - 0.0027 18.2 0.0 0.01 16.3 0.0 2.1 1 1 0 1 1 1 1 Orthopoxvirus C10L protein ADK PF00406.17 CCH62919.1 - 6.2e-60 201.4 0.0 7.4e-60 201.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCH62919.1 - 1.4e-14 53.4 0.0 2.9e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CCH62919.1 - 2.1e-06 27.6 0.0 3.4e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCH62919.1 - 1.9e-05 25.4 0.0 6.5e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCH62919.1 - 0.00075 19.8 0.0 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCH62919.1 - 0.02 13.9 0.0 0.024 13.7 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin CFIA_Pcf11 PF11526.3 CCH62920.1 - 8.6e-16 57.8 41.6 4.1e-14 52.4 11.0 4.6 3 1 1 4 4 4 2 Subunit of cleavage factor IA Pcf11 zf-H2C2_2 PF13465.1 CCH62920.1 - 0.67 10.3 2.9 5.2 7.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain MalF_P2 PF14785.1 CCH62921.1 - 0.00092 19.1 2.4 0.0042 16.9 1.6 2.1 1 0 0 1 1 1 1 Maltose transport system permease protein MalF P2 domain DUF3853 PF12964.2 CCH62921.1 - 0.042 13.6 0.1 0.15 11.8 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) DUF3767 PF12597.3 CCH62922.1 - 9e-38 128.5 0.0 1.4e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Romo1 PF10247.4 CCH62922.1 - 0.026 14.7 0.0 5.7 7.2 0.0 2.2 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF1043 PF06295.7 CCH62922.1 - 0.031 13.9 0.5 0.85 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) 60KD_IMP PF02096.15 CCH62923.1 - 3.7e-16 59.3 6.8 1.3e-15 57.5 4.7 1.8 1 1 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.8 CCH62924.1 - 2.6e-27 94.5 0.3 3e-27 94.2 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNHCP PF12647.2 CCH62924.1 - 0.15 11.9 1.0 0.18 11.6 0.7 1.2 1 0 0 1 1 1 0 RNHCP domain zf-TFIIB PF13453.1 CCH62924.1 - 0.23 10.6 1.2 0.35 10.0 0.4 1.6 1 1 0 1 1 1 0 Transcription factor zinc-finger MFS_1 PF07690.11 CCH62925.1 - 4.5e-18 65.0 23.9 4.5e-18 65.0 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 CCH62926.1 - 1.7e-07 31.1 14.0 0.00012 22.1 0.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62926.1 - 2.1e-05 24.4 15.7 0.0011 19.1 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCH62926.1 - 0.00017 21.6 14.5 0.00057 20.0 2.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 CCH62926.1 - 0.0067 16.6 0.9 0.0067 16.6 0.6 3.2 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 CCH62926.1 - 0.74 10.0 7.2 10 6.4 2.0 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Arrestin_C PF02752.17 CCH62927.1 - 1.4e-11 44.6 0.0 1.6e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCH62927.1 - 4.6e-07 29.7 0.5 4.3e-06 26.6 0.4 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HSP70 PF00012.15 CCH62929.1 - 1.6e-209 696.7 9.0 2e-209 696.4 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCH62929.1 - 4.9e-19 68.0 0.9 3.9e-16 58.5 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCH62929.1 - 5.2e-05 22.9 0.0 9.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CCH62929.1 - 0.0056 16.0 0.1 0.24 10.6 0.0 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 CCH62929.1 - 0.58 10.0 4.8 55 3.6 0.0 3.7 2 1 0 2 2 2 0 Cell division protein FtsA P21-Arc PF04062.9 CCH62930.1 - 4.1e-80 267.6 0.1 4.6e-80 267.4 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.17 CCH62931.1 - 1.3e-74 251.0 0.6 3e-74 249.9 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 CCH62931.1 - 6.4e-36 123.2 0.0 6.4e-36 123.2 0.0 3.3 4 0 0 4 4 4 1 Pleckstrin homology domain RhoGEF PF00621.15 CCH62931.1 - 6.1e-31 107.6 0.0 1.3e-30 106.6 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 CCH62931.1 - 6.8e-13 48.1 0.0 1.5e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.13 CCH62932.1 - 2.6e-60 203.8 30.6 3.3e-60 203.4 21.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Cyt_c_ox_IV PF12270.3 CCH62932.1 - 0.25 11.1 8.0 0.84 9.3 0.2 3.6 2 1 2 4 4 4 0 Cytochrome c oxidase subunit IV zf-C2H2_6 PF13912.1 CCH62933.1 - 2.9e-05 23.8 9.6 0.001 18.9 0.3 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCH62933.1 - 8.6e-05 22.6 21.2 0.0042 17.3 1.3 5.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCH62933.1 - 0.0025 18.0 2.3 0.0025 18.0 1.6 5.5 5 1 0 5 5 5 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCH62933.1 - 0.0082 16.3 0.8 0.0082 16.3 0.6 4.9 5 1 1 6 6 6 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCH62933.1 - 0.23 11.6 3.4 0.38 10.9 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.1 CCH62933.1 - 0.59 9.9 3.5 10 5.9 0.2 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-Di19 PF05605.7 CCH62933.1 - 1.1 9.4 6.4 0.7 10.0 1.1 3.1 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 CCH62933.1 - 1.6 8.4 13.1 6.8 6.4 0.1 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.2 CCH62933.1 - 2 8.7 6.3 0.3 11.3 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 CCH62933.1 - 6.1 6.5 10.9 1.2 8.8 0.9 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif KRE9 PF05390.6 CCH62934.1 - 1.3e-29 102.6 0.2 4.9e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCH62934.1 - 2.3e-06 27.9 0.5 6e-06 26.6 0.3 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family La PF05383.12 CCH62935.1 - 3.6e-23 81.1 0.0 3e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 CCH62935.1 - 0.0048 16.8 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SprB PF13573.1 CCH62935.1 - 0.078 12.5 2.5 0.17 11.5 1.7 1.5 1 0 0 1 1 1 0 SprB repeat FAM217 PF15344.1 CCH62936.1 - 1.2 8.6 13.4 1.5 8.3 9.3 1.1 1 0 0 1 1 1 0 FAM217 family TFIIA PF03153.8 CCH62936.1 - 3.1 7.5 6.9 3.4 7.4 4.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 CCH62937.1 - 3.1e-19 68.9 18.4 4.1e-19 68.4 12.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SecY PF00344.15 CCH62938.1 - 4.9e-86 288.7 15.7 6e-86 288.4 10.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCH62938.1 - 4.7e-18 64.4 1.2 1.5e-17 62.7 0.1 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p DUF3494 PF11999.3 CCH62938.1 - 0.48 10.0 4.1 0.69 9.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3494) ADH_zinc_N PF00107.21 CCH62939.1 - 4.7e-13 48.8 0.0 2.7e-12 46.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCH62939.1 - 6.3e-05 22.6 0.3 0.00016 21.3 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ank_2 PF12796.2 CCH62940.1 - 9.5e-08 32.2 0.0 0.018 15.3 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) KilA-N PF04383.8 CCH62940.1 - 1.3e-07 31.1 2.9 9.4e-07 28.4 0.1 3.3 2 1 0 2 2 2 1 KilA-N domain Ank_5 PF13857.1 CCH62940.1 - 5.7e-06 26.4 0.1 0.066 13.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCH62940.1 - 7.9e-06 26.2 0.1 0.27 11.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCH62940.1 - 0.0013 18.4 0.4 0.2 11.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 CCH62940.1 - 0.012 15.7 0.6 2.4 8.6 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeat Y_phosphatase3 PF13350.1 CCH62941.1 - 8.7e-39 133.4 0.0 1.5e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_6 PF12697.2 CCH62941.1 - 2.7e-11 43.7 0.0 4.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCH62941.1 - 4.6e-11 42.6 0.0 7.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 CCH62941.1 - 1.8e-05 24.7 0.0 0.0001 22.3 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Hydrolase_4 PF12146.3 CCH62941.1 - 0.00034 20.4 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Y_phosphatase2 PF03162.8 CCH62941.1 - 0.00035 19.9 0.0 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Chlorophyllase2 PF12740.2 CCH62941.1 - 0.0051 15.7 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF915 PF06028.6 CCH62941.1 - 0.0076 15.3 0.2 2.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Y_phosphatase PF00102.22 CCH62941.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_S9 PF00326.16 CCH62941.1 - 0.027 13.7 0.0 0.6 9.2 0.0 2.4 1 1 0 1 1 1 0 Prolyl oligopeptidase family CRAL_TRIO PF00650.15 CCH62942.1 - 1.2e-42 145.1 0.3 2.4e-42 144.1 0.1 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCH62942.1 - 2.5e-12 46.9 0.2 4e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCH62942.1 - 0.00023 21.2 1.0 0.00077 19.5 0.1 2.4 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain tRNA-synt_1 PF00133.17 CCH62944.1 - 8.8e-54 182.5 1.0 4.1e-16 58.1 0.3 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CCH62944.1 - 4.9e-39 133.5 0.0 9.4e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CCH62944.1 - 2.1e-29 102.3 1.2 6.4e-22 77.7 0.1 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCH62944.1 - 2.1e-07 30.8 0.6 2.1e-07 30.8 0.4 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 CCH62944.1 - 5.4e-05 22.1 0.9 9.2e-05 21.4 0.0 1.8 3 0 0 3 3 3 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 CCH62944.1 - 0.00028 20.1 0.0 0.25 10.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain SMC_N PF02463.14 CCH62945.1 - 1.2e-14 54.0 0.5 1.2e-14 54.0 0.4 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCH62945.1 - 3.6e-07 30.7 48.0 3.6e-07 30.7 33.3 6.6 1 1 1 3 3 2 1 AAA domain TPR_MLP1_2 PF07926.7 CCH62945.1 - 8.8e-06 25.4 13.1 8.8e-06 25.4 9.1 6.5 3 2 3 6 6 6 2 TPR/MLP1/MLP2-like protein AAA_15 PF13175.1 CCH62945.1 - 8.8e-06 25.0 37.9 8.8e-06 25.0 26.3 3.2 2 1 1 3 3 1 1 AAA ATPase domain AAA_29 PF13555.1 CCH62945.1 - 0.00025 20.5 0.0 0.00058 19.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain WEMBL PF05701.6 CCH62945.1 - 0.00094 17.7 15.0 0.00094 17.7 10.4 3.4 2 2 1 3 3 2 2 Weak chloroplast movement under blue light COG5 PF10392.4 CCH62945.1 - 0.0015 18.5 2.6 0.0015 18.5 1.8 4.4 4 1 0 4 4 4 1 Golgi transport complex subunit 5 AAA_21 PF13304.1 CCH62945.1 - 0.0061 16.5 4.6 0.0061 16.5 3.2 5.6 2 2 3 5 5 4 2 AAA domain SbcCD_C PF13558.1 CCH62945.1 - 0.0096 15.8 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Cytochrom_C_2 PF01322.15 CCH62945.1 - 0.04 14.4 0.1 0.04 14.4 0.1 3.9 2 2 1 4 4 4 0 Cytochrome C' DUF3584 PF12128.3 CCH62945.1 - 0.052 10.8 60.6 0.03 11.6 15.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) ABC_tran PF00005.22 CCH62945.1 - 0.066 13.5 0.1 0.066 13.5 0.1 5.7 4 2 0 4 4 1 0 ABC transporter IncA PF04156.9 CCH62945.1 - 0.074 12.6 72.5 0.045 13.3 7.9 4.5 2 2 2 4 4 4 0 IncA protein AAA_13 PF13166.1 CCH62945.1 - 0.39 9.1 93.9 0.81 8.0 21.1 5.2 3 2 2 5 5 5 0 AAA domain UPF0227 PF05728.7 CCH62945.1 - 0.52 10.0 6.9 0.32 10.6 0.4 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) EzrA PF06160.7 CCH62945.1 - 0.99 7.5 64.2 0.0041 15.3 21.6 3.0 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF869 PF05911.6 CCH62945.1 - 1.1 7.3 60.1 0.0081 14.4 12.6 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) Uso1_p115_head PF04869.9 CCH62946.1 - 1.1e-95 320.0 2.2 1.8e-57 194.4 0.1 2.9 2 0 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 CCH62946.1 - 3.4e-10 39.9 20.6 3.4e-10 39.9 14.3 12.8 2 1 10 12 12 12 2 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.4 CCH62946.1 - 0.00021 21.1 57.6 0.00043 20.1 17.5 11.7 1 1 12 14 14 14 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rad52_Rad22 PF04098.10 CCH62947.1 - 7.7e-28 97.1 0.2 1e-27 96.7 0.2 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein ROF PF07073.7 CCH62947.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) IKI3 PF04762.7 CCH62948.1 - 0 1093.4 7.4 0 1092.8 5.1 1.2 1 0 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 CCH62948.1 - 0.062 13.1 12.1 2.9 7.8 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62948.1 - 8.3 6.5 9.7 6 7.0 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S14 PF00253.16 CCH62949.1 - 1.7e-18 65.7 5.8 1.9e-18 65.6 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 CCH62949.1 - 0.043 13.8 1.7 1.9 8.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Peptidase_M16 PF00675.15 CCH62950.1 - 1.4e-37 128.6 0.1 1.2e-36 125.6 0.0 2.6 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCH62950.1 - 1.7e-30 106.0 1.0 1.3e-15 57.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain UQ_con PF00179.21 CCH62952.1 - 5.8e-43 145.6 0.1 6.6e-43 145.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCH62952.1 - 4.6e-06 26.4 0.0 5.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCH62952.1 - 0.15 12.0 1.9 0.28 11.0 1.2 1.7 1 1 1 2 2 2 0 RWD domain Pex19 PF04614.7 CCH62953.1 - 5.2e-49 167.1 22.7 6.3e-49 166.8 15.7 1.1 1 0 0 1 1 1 1 Pex19 protein family DUF2408 PF10303.4 CCH62953.1 - 8.9 6.4 15.3 0.71 9.9 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) CFEM PF05730.6 CCH62954.1 - 4.7e-09 35.9 14.5 1e-08 34.8 10.0 1.6 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 CCH62954.1 - 0.16 11.3 16.0 0.19 11.0 11.1 1.0 1 0 0 1 1 1 0 Vta1 like Sec10 PF07393.6 CCH62954.1 - 2.2 6.3 7.7 2.7 6.0 5.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF566 PF04484.7 CCH62954.1 - 5.6 6.3 22.1 7 6.0 15.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) FAM220 PF15487.1 CCH62954.1 - 5.7 6.2 18.8 7.7 5.7 13.0 1.3 1 0 0 1 1 1 0 FAM220 family Herpes_BLLF1 PF05109.8 CCH62954.1 - 6.2 4.6 32.1 7.2 4.4 22.3 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Pol_alpha_B_N PF08418.5 CCH62954.1 - 8.7 5.8 17.6 14 5.0 12.2 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal zf-RING_5 PF14634.1 CCH62955.1 - 1.6e-07 30.9 8.5 2.9e-07 30.1 5.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCH62955.1 - 0.072 13.1 8.1 0.14 12.2 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 CCH62955.1 - 0.087 12.3 5.8 0.19 11.2 4.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FANCL_C PF11793.3 CCH62955.1 - 0.3 11.0 4.4 0.14 12.1 1.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.1 CCH62955.1 - 1.4 8.8 5.7 2.4 8.0 3.9 1.4 1 0 0 1 1 1 0 Ring finger domain Sec1 PF00995.18 CCH62956.1 - 1.5e-70 238.4 20.9 2.1e-70 238.0 14.5 1.1 1 0 0 1 1 1 1 Sec1 family PTS_IIA PF02255.11 CCH62956.1 - 0.069 13.0 0.4 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Lzipper-MIP1 PF14389.1 CCH62958.1 - 0.0032 17.5 3.4 0.0076 16.3 2.3 1.6 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 DUF3573 PF12097.3 CCH62958.1 - 0.26 9.8 5.2 0.17 10.4 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) ACCA PF03255.9 CCH62958.1 - 0.32 10.5 4.1 0.072 12.6 0.6 1.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit cwf21 PF08312.7 CCH62958.1 - 0.98 9.3 10.0 3.4 7.6 0.4 2.4 2 0 0 2 2 2 0 cwf21 domain Dus PF01207.12 CCH62959.1 - 1.5e-40 138.9 0.0 2.4e-31 108.7 0.1 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CCH62959.1 - 0.29 10.8 9.3 0.26 11.0 2.9 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_jaz PF12171.3 CCH62960.1 - 0.00033 20.7 5.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCH62960.1 - 0.00066 19.8 16.3 0.057 13.7 0.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62960.1 - 0.0014 18.8 17.6 0.043 14.1 0.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 CCH62960.1 - 0.053 13.7 0.9 4.7 7.5 0.1 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CCH62960.1 - 0.079 13.2 19.2 0.16 12.3 1.3 3.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 CCH62960.1 - 0.56 10.1 4.3 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Nucleoplasmin PF03066.10 CCH62960.1 - 0.97 8.9 6.0 1.6 8.2 4.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 CCH62960.1 - 1.9 8.0 4.2 4.2 6.9 2.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1765 PF08578.5 CCH62962.1 - 7.8e-15 55.0 4.6 7.8e-15 55.0 3.2 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF1765) PMT PF02366.13 CCH62962.1 - 0.036 13.4 3.9 0.066 12.5 2.7 1.3 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4050 PF13259.1 CCH62963.1 - 4.2e-21 75.1 9.8 2.9e-20 72.4 6.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) His_Phos_2 PF00328.17 CCH62964.1 - 2e-124 415.4 1.4 2.8e-124 414.9 0.9 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCH62964.1 - 5.3e-06 26.0 0.1 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCH62964.1 - 0.0081 16.0 0.0 0.033 14.0 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Sipho_tail PF05709.6 CCH62965.1 - 0.073 12.1 0.1 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein Pribosyl_synth PF14572.1 CCH62966.1 - 3.1e-40 137.8 2.2 1.2e-31 109.8 0.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCH62966.1 - 9e-39 131.8 0.0 2.5e-38 130.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCH62966.1 - 8.5e-07 28.7 0.0 0.0089 15.7 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Acyl_transf_1 PF00698.16 CCH62967.1 - 1.2e-92 310.6 0.0 3.8e-92 309.0 0.0 1.9 1 0 0 1 1 1 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CCH62967.1 - 1.4e-35 121.3 0.1 3e-35 120.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CCH62967.1 - 1.3e-29 101.7 0.0 3.4e-29 100.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 CCH62967.1 - 3.2e-14 52.8 0.0 1.1e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 CCH62967.1 - 0.0024 17.0 0.0 0.045 12.8 0.0 2.6 1 1 0 1 1 1 1 Nitronate monooxygenase Mtr2 PF10429.4 CCH62968.1 - 4.1e-63 212.0 0.8 4.9e-63 211.8 0.5 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Mo25 PF08569.6 CCH62969.1 - 7.5e-97 324.3 24.0 8.7e-97 324.1 16.6 1.0 1 0 0 1 1 1 1 Mo25-like Legionella_OMP PF05150.7 CCH62969.1 - 1.5 7.8 5.1 4.2 6.3 0.2 2.7 3 0 0 3 3 3 0 Legionella pneumophila major outer membrane protein precursor CDC73 PF05179.9 CCH62970.1 - 1.4e-67 227.9 3.9 1.9e-67 227.4 2.7 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family EF-hand_1 PF00036.27 CCH62971.1 - 6.6e-25 84.4 13.7 9.1e-06 24.6 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCH62971.1 - 2e-20 72.6 8.8 4.3e-11 42.7 1.2 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CCH62971.1 - 2.8e-20 70.3 4.9 0.0002 20.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCH62971.1 - 1.6e-16 58.7 13.6 0.00087 18.5 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CCH62971.1 - 1.2e-12 47.2 15.8 0.0035 16.9 0.2 4.4 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CCH62971.1 - 2.9e-07 30.5 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CCH62971.1 - 7.2e-07 28.8 11.1 0.12 12.1 0.2 4.1 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCH62971.1 - 8.5e-06 25.5 0.1 0.54 10.2 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.12 CCH62972.1 - 5.4e-39 134.2 0.1 1.8e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Amidohydro_4 PF13147.1 CCH62973.1 - 2e-06 28.0 0.0 2.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CCH62973.1 - 5.6e-06 26.1 0.0 1.9e-05 24.4 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase Ribosomal_L1 PF00687.16 CCH62974.1 - 5.5e-20 71.6 0.6 6.5e-20 71.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SUI1 PF01253.17 CCH62975.1 - 3.9e-14 52.2 0.0 1.3e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 CCH62975.1 - 9.1e-05 22.0 0.0 0.00026 20.6 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.15 CCH62975.1 - 0.0043 16.7 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 PUA domain Phosphorylase PF00343.15 CCH62976.1 - 0 1019.9 3.5 0 1019.6 2.4 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase HD_3 PF13023.1 CCH62976.1 - 0.041 13.6 0.0 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 HD domain Peptidase_S10 PF00450.17 CCH62977.1 - 1.6e-98 330.5 0.2 2.5e-98 329.9 0.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Daxx PF03344.10 CCH62977.1 - 0.0015 17.0 14.6 0.0023 16.5 10.1 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 CCH62977.1 - 0.0048 14.8 18.1 0.0069 14.3 12.6 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CCH62977.1 - 0.0052 14.8 12.3 0.0073 14.4 8.6 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 CCH62977.1 - 0.021 13.8 15.2 0.041 12.9 10.5 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 CCH62977.1 - 0.053 12.7 18.3 0.079 12.2 12.7 1.1 1 0 0 1 1 1 0 SDA1 DUF912 PF06024.7 CCH62977.1 - 0.11 12.5 4.5 0.61 10.1 3.0 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2722 PF10846.3 CCH62977.1 - 0.86 8.5 9.3 1.4 7.8 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RP-C_C PF11800.3 CCH62977.1 - 1.1 8.9 2.8 1.8 8.2 1.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region VID27 PF08553.5 CCH62977.1 - 2.8 6.0 16.6 4.5 5.3 11.5 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein RRN3 PF05327.6 CCH62977.1 - 3.7 5.5 10.6 5.9 4.8 7.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDP-OH_P_transf PF01066.16 CCH62978.1 - 2.4e-11 43.8 4.1 2.4e-11 43.8 2.8 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MMPL PF03176.10 CCH62978.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 MMPL family EutQ PF06249.7 CCH62978.1 - 0.12 11.8 0.3 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ ACOX PF01756.14 CCH62979.1 - 2.5e-49 167.1 0.0 7e-49 165.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CCH62979.1 - 1.2e-16 59.9 0.4 2.5e-16 58.9 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CCH62979.1 - 2.1e-13 50.6 0.2 2.1e-12 47.4 0.1 2.6 2 1 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CCH62979.1 - 0.0012 18.9 0.0 0.0043 17.1 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Baculo_gp41 PF04700.7 CCH62979.1 - 0.015 14.7 1.3 0.056 12.8 0.3 2.3 2 0 0 2 2 2 0 Structural glycoprotein p40/gp41 conserved region CART PF06373.6 CCH62979.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Clathrin PF00637.15 CCH62980.1 - 8.6e-179 586.2 61.0 7e-31 106.7 1.3 8.5 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CCH62980.1 - 1.8e-20 72.5 0.1 8.6e-18 63.9 0.0 3.8 4 0 0 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.15 CCH62980.1 - 3.6e-05 23.7 9.7 0.47 10.8 0.2 6.1 7 0 0 7 7 7 2 Clathrin propeller repeat TPR_7 PF13176.1 CCH62980.1 - 4.7e-05 22.8 3.0 0.82 9.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Clathrin-link PF09268.5 CCH62980.1 - 0.0033 16.4 0.0 0.021 13.8 0.0 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 CCH62980.1 - 0.015 15.2 7.2 1.2 9.1 0.2 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCH62980.1 - 1.4 8.6 19.9 0.19 11.3 1.3 6.2 7 1 0 7 7 7 0 TPR repeat TPR_1 PF00515.23 CCH62980.1 - 6.3 6.5 13.9 4.5 7.0 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCH62980.1 - 6.9 6.7 8.7 1.7 8.6 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCH62980.1 - 7.8 6.6 15.7 2.8 8.0 0.1 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat SPT16 PF08644.6 CCH62981.1 - 5e-50 169.2 0.1 5e-50 169.2 0.0 1.9 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CCH62981.1 - 6.1e-43 146.1 1.2 3e-42 143.9 0.0 2.8 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CCH62981.1 - 6.8e-26 91.1 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CCH62981.1 - 4.9e-18 64.9 0.1 1.9e-17 63.0 0.1 2.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like AMPKBI PF04739.10 CCH62982.1 - 7.6e-33 112.3 2.0 7.6e-33 112.3 1.4 2.1 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF3736 PF12540.3 CCH62982.1 - 0.036 14.3 3.3 0.075 13.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) zf-H2C2_2 PF13465.1 CCH62983.1 - 9.8e-11 41.3 16.5 1.3e-07 31.5 1.3 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCH62983.1 - 2.4e-09 36.9 14.4 1.9e-05 24.6 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCH62983.1 - 4.2e-09 36.0 10.5 9.6e-06 25.5 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCH62983.1 - 0.0036 17.4 6.2 0.29 11.3 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCH62983.1 - 0.29 11.4 5.2 1.7 8.9 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCH62983.1 - 0.36 10.9 4.5 0.76 9.9 3.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PX PF00787.19 CCH62984.1 - 5.1e-10 39.1 0.2 1.9e-09 37.3 0.1 1.9 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 CCH62984.1 - 8.4e-07 28.5 3.1 3.2e-06 26.7 2.1 2.0 1 0 0 1 1 1 1 SNARE domain DUF1869 PF08956.5 CCH62984.1 - 0.14 11.7 1.4 7.7 6.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) WD40 PF00400.27 CCH62985.1 - 1.2e-13 50.3 10.5 1.5e-07 31.0 0.2 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.7 CCH62985.1 - 0.00037 18.4 0.0 0.00079 17.3 0.0 1.5 2 0 0 2 2 2 1 IKI3 family ABC_tran PF00005.22 CCH62988.1 - 1.3e-48 164.8 1.2 1.2e-23 83.9 0.0 2.8 4 0 0 4 4 2 2 ABC transporter ABC_tran_2 PF12848.2 CCH62988.1 - 1.8e-21 75.7 2.6 1.8e-21 75.7 1.8 2.8 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 CCH62988.1 - 4.8e-21 75.9 3.8 2.4e-05 24.4 0.4 4.3 2 2 1 3 3 3 3 AAA domain AAA_22 PF13401.1 CCH62988.1 - 5.5e-09 36.2 0.0 0.0028 17.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CCH62988.1 - 1.1e-08 34.5 7.1 0.037 13.2 0.1 4.8 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCH62988.1 - 1.4e-08 34.1 0.0 0.0026 17.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCH62988.1 - 2.8e-08 34.5 0.0 0.0026 18.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CCH62988.1 - 1.1e-07 32.3 0.2 0.007 16.8 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_18 PF13238.1 CCH62988.1 - 2.1e-07 31.3 1.6 0.0018 18.5 0.0 3.4 4 1 0 4 4 2 2 AAA domain DUF258 PF03193.11 CCH62988.1 - 2.6e-07 29.9 0.0 0.00018 20.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCH62988.1 - 3.7e-06 26.6 0.0 0.16 11.3 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 CCH62988.1 - 4.5e-06 26.6 0.0 0.032 14.1 0.0 3.1 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA PF00004.24 CCH62988.1 - 5.6e-06 26.5 0.1 0.11 12.6 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCH62988.1 - 8.1e-06 25.9 0.1 0.058 13.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.1 CCH62988.1 - 8.4e-06 25.8 0.1 0.11 12.4 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain NACHT PF05729.7 CCH62988.1 - 9.6e-06 25.3 0.5 0.18 11.4 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_15 PF13175.1 CCH62988.1 - 2.7e-05 23.4 0.3 0.53 9.2 0.0 3.8 4 1 0 5 5 4 2 AAA ATPase domain AAA_23 PF13476.1 CCH62988.1 - 2.9e-05 24.4 0.0 0.011 16.1 0.0 4.3 5 0 0 5 5 3 2 AAA domain AAA_14 PF13173.1 CCH62988.1 - 5.9e-05 22.9 0.0 0.39 10.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCH62988.1 - 5.9e-05 22.7 0.3 0.0029 17.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCH62988.1 - 0.00012 21.9 0.0 0.38 10.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCH62988.1 - 0.00013 20.9 0.0 0.3 9.9 0.0 3.1 3 1 0 3 3 2 2 NB-ARC domain VirE PF05272.6 CCH62988.1 - 0.00014 21.3 0.2 0.061 12.7 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E AAA_28 PF13521.1 CCH62988.1 - 0.00016 21.6 0.0 0.84 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MCM PF00493.18 CCH62988.1 - 0.00051 18.9 1.7 0.13 11.0 0.0 2.9 3 0 0 3 3 3 1 MCM2/3/5 family T2SE PF00437.15 CCH62988.1 - 0.00064 18.6 0.0 0.015 14.2 0.0 2.4 2 1 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 CCH62988.1 - 0.00065 19.5 3.1 0.58 9.9 0.0 3.7 3 1 1 4 4 3 2 Dynamin family AAA_25 PF13481.1 CCH62988.1 - 0.0015 18.0 0.0 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CCH62988.1 - 0.0033 17.1 7.8 0.16 11.6 0.0 3.6 4 0 0 4 4 3 2 Archaeal ATPase AAA_5 PF07728.9 CCH62988.1 - 0.005 16.5 0.0 2.7 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CCH62988.1 - 0.005 15.7 1.5 1.8 7.4 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) NTPase_1 PF03266.10 CCH62988.1 - 0.0053 16.4 0.1 0.62 9.7 0.0 2.6 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.4 CCH62988.1 - 0.0071 15.8 0.1 2.8 7.4 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 CCH62988.1 - 0.011 14.5 0.0 0.82 8.4 0.0 2.8 3 0 0 3 3 3 0 ArgK protein SbcCD_C PF13558.1 CCH62988.1 - 0.02 14.8 0.4 1.3 8.9 0.0 3.3 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 CCH62988.1 - 0.032 12.9 0.1 2.6 6.6 0.0 2.5 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 CCH62988.1 - 0.047 13.3 0.0 7.1 6.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CCH62988.1 - 0.059 12.8 0.0 5.5 6.4 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family FeoB_N PF02421.13 CCH62988.1 - 0.063 12.5 0.0 2.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.12 CCH62988.1 - 0.07 12.9 9.6 0.3 10.8 0.0 3.5 4 1 1 5 5 3 0 Domain of unknown function DUF87 MutS_V PF00488.16 CCH62988.1 - 0.12 11.7 0.0 6 6.1 0.0 2.3 2 0 0 2 2 2 0 MutS domain V G-alpha PF00503.15 CCH62988.1 - 1.4 7.5 6.1 26 3.3 3.1 2.9 2 1 0 2 2 2 0 G-protein alpha subunit DUF4407 PF14362.1 CCH62988.1 - 3.5 6.5 7.7 2.8 6.8 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HAD_2 PF13419.1 CCH62990.1 - 1.8e-20 73.8 0.3 2.7e-20 73.3 0.2 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DNA_primase_S PF01896.14 CCH62990.1 - 0.031 14.0 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit GATA PF00320.22 CCH62991.1 - 3.5e-15 55.0 4.9 3.5e-15 55.0 3.4 2.2 2 0 0 2 2 2 1 GATA zinc finger eIF-5_eIF-2B PF01873.12 CCH62991.1 - 0.0014 18.2 0.3 0.0042 16.7 0.2 1.8 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 CCH62991.1 - 0.021 14.1 2.8 0.049 12.9 1.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding RRN7 PF11781.3 CCH62991.1 - 0.15 11.5 0.6 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 XPG_I PF00867.13 CCH62992.1 - 1.3e-23 82.8 0.1 2.7e-22 78.6 0.0 3.2 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.12 CCH62992.1 - 6.5e-06 26.3 0.0 2.1e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain PMSR PF01625.16 CCH62993.1 - 6e-49 165.9 0.6 7.4e-49 165.6 0.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SAPS PF04499.10 CCH62995.1 - 4.5e-112 375.1 49.5 4.5e-112 375.1 34.3 3.0 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein DnaJ PF00226.26 CCH62996.1 - 1.8e-13 50.0 6.0 3.5e-13 49.0 4.2 1.5 1 0 0 1 1 1 1 DnaJ domain Palm_thioest PF02089.10 CCH62996.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Jiraiya PF15038.1 CCH62996.1 - 0.082 12.3 0.1 0.78 9.1 0.0 2.2 2 1 1 3 3 3 0 Jiraiya Adaptin_binding PF10199.4 CCH62998.1 - 9.4e-05 22.7 2.3 0.08 13.2 0.0 2.3 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 HORMA PF02301.13 CCH62998.1 - 0.064 12.7 0.4 0.097 12.1 0.3 1.4 1 1 0 1 1 1 0 HORMA domain Peptidase_M20 PF01546.23 CCH62999.1 - 1.9e-29 102.5 0.0 2.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCH62999.1 - 7.5e-14 51.4 0.0 1.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain GIDA PF01134.17 CCH63000.1 - 2.2e-154 514.0 0.0 2.9e-154 513.6 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CCH63000.1 - 2.7e-19 68.9 0.3 1.2e-18 66.8 0.1 2.1 2 0 0 2 2 2 1 GidA associated domain 3 FAD_oxidored PF12831.2 CCH63000.1 - 7.8e-07 28.5 0.2 1.3e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCH63000.1 - 1.3e-06 28.4 0.3 3.4e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCH63000.1 - 1.9e-06 27.0 2.2 0.038 12.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCH63000.1 - 4.2e-05 22.5 3.0 0.0016 17.4 1.9 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CCH63000.1 - 0.022 13.2 2.2 1.2 7.5 0.7 2.3 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 CCH63000.1 - 0.045 14.1 1.3 0.11 12.9 0.9 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH63000.1 - 0.16 12.0 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cse1 PF08506.5 CCH63001.1 - 8.7e-163 541.1 12.3 8.7e-163 541.1 8.5 1.9 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 CCH63001.1 - 2.1e-106 355.8 7.7 2.1e-106 355.8 5.3 1.5 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CCH63001.1 - 1.1e-16 60.4 0.6 2.5e-15 56.1 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCH63001.1 - 0.00044 20.1 6.8 0.0019 18.0 0.1 4.5 4 0 0 4 4 4 1 Exportin 1-like protein Ank PF00023.25 CCH63002.1 - 3.4e-14 51.8 0.4 2e-05 24.1 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 CCH63002.1 - 2.2e-11 43.9 0.6 1.1e-10 41.6 0.2 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCH63002.1 - 2.1e-10 39.8 0.1 0.00025 20.9 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCH63002.1 - 2.4e-10 40.3 0.6 1.4e-05 25.1 0.1 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCH63002.1 - 6.4e-09 36.0 3.2 6.4e-06 26.5 0.6 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF2638 PF10937.3 CCH63003.1 - 1.5e-22 80.7 0.1 1.7e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Ribosomal_L18_c PF14204.1 CCH63004.1 - 0.019 15.5 0.9 0.06 13.9 0.7 1.8 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Ppx-GppA PF02541.11 CCH63005.1 - 2e-54 184.7 0.0 2.5e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SAC3_GANP PF03399.11 CCH63006.1 - 2.3e-29 102.4 0.5 2.9e-29 102.1 0.4 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCH63006.1 - 3e-17 62.7 0.1 4.4e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Vip3A_N PF12495.3 CCH63006.1 - 0.021 14.4 2.1 0.038 13.6 1.4 1.5 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Hexokinase_2 PF03727.11 CCH63007.1 - 2.4e-91 305.2 0.0 3.1e-91 304.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCH63007.1 - 1.8e-82 275.6 0.0 2.9e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 CCH63007.1 - 0.014 14.7 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF457 PF04307.9 CCH63008.1 - 0.76 9.0 5.4 3.7 6.8 3.7 2.0 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Oxidored_FMN PF00724.15 CCH63010.1 - 6.4e-116 387.0 0.0 7.4e-116 386.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sugar_tr PF00083.19 CCH63011.1 - 8.4e-160 532.2 38.6 9.6e-160 532.0 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCH63011.1 - 3.3e-30 104.9 35.5 1.3e-27 96.5 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCH63011.1 - 0.001 17.3 4.0 0.001 17.3 2.8 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector ATP1G1_PLM_MAT8 PF02038.11 CCH63011.1 - 0.016 14.2 2.5 0.72 8.9 0.8 2.9 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PDR_CDR PF06422.7 CCH63011.1 - 1.4 8.6 5.7 3.5 7.3 0.0 3.6 3 0 0 3 3 3 0 CDR ABC transporter hDGE_amylase PF14701.1 CCH63012.1 - 1.8e-168 560.8 4.3 2.6e-168 560.3 3.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CCH63012.1 - 3.1e-123 411.1 0.0 5.5e-123 410.3 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CCH63012.1 - 3.1e-75 252.7 0.1 5.4e-75 251.9 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CCH63012.1 - 1.2e-22 79.4 0.2 5.2e-22 77.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CCH63012.1 - 1e-07 31.6 1.0 0.00023 20.6 0.9 2.7 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_2 PF00535.21 CCH63013.1 - 2.8e-29 101.9 0.0 3.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CCH63013.1 - 4.4e-07 29.2 0.0 7.1e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CCH63013.1 - 7.8e-06 25.8 0.0 9.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Sec23_trunk PF04811.10 CCH63014.1 - 8.8e-68 228.2 0.0 1.2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCH63014.1 - 6.5e-35 118.6 0.1 1.7e-34 117.3 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCH63014.1 - 1.2e-29 102.7 0.6 2.3e-29 101.7 0.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCH63014.1 - 1.9e-13 49.7 9.7 3.2e-13 48.9 6.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCH63014.1 - 1.3e-11 43.9 0.0 3.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat NBP1 PF08537.5 CCH63015.1 - 5.4e-38 130.9 27.6 8.7e-37 127.0 19.1 1.9 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF3251 PF11622.3 CCH63015.1 - 0.24 10.7 1.6 0.37 10.1 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3251) IncA PF04156.9 CCH63015.1 - 1.8 8.1 15.0 1.8e+02 1.5 10.4 2.6 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 CCH63015.1 - 1.8 8.5 11.6 0.2 11.5 1.8 3.0 2 1 0 2 2 2 0 FlxA-like protein Prefoldin PF02996.12 CCH63015.1 - 2.2 7.9 10.4 0.088 12.4 0.9 2.9 2 1 1 3 3 3 0 Prefoldin subunit DUF724 PF05266.9 CCH63015.1 - 3.1 7.3 11.5 0.65 9.5 5.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Pyridox_oxidase PF01243.15 CCH63016.1 - 1e-16 60.7 0.1 3.1e-16 59.1 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 CCH63016.1 - 1.5e-05 24.8 0.2 0.00012 21.9 0.1 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 CCH63016.1 - 0.00094 19.0 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PWWP PF00855.12 CCH63017.1 - 4.4e-14 52.4 0.9 8e-14 51.6 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Aa_trans PF01490.13 CCH63019.1 - 0.032 12.7 1.8 0.051 12.0 1.2 1.3 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein NfeD PF01957.13 CCH63019.1 - 0.062 13.4 0.2 0.074 13.1 0.2 1.0 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding ABC2_membrane_4 PF12730.2 CCH63019.1 - 0.076 12.1 0.7 0.084 12.0 0.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Med10 PF09748.4 CCH63020.1 - 1.1e-44 151.3 0.8 1.1e-44 151.3 0.6 1.3 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex DUF1281 PF06924.6 CCH63020.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) PBS_linker_poly PF00427.16 CCH63020.1 - 0.03 13.9 0.9 0.087 12.4 0.1 2.1 2 1 0 2 2 2 0 Phycobilisome Linker polypeptide Laminin_II PF06009.7 CCH63020.1 - 0.037 13.7 1.4 0.053 13.2 0.6 1.5 2 0 0 2 2 2 0 Laminin Domain II DUF3877 PF12993.2 CCH63020.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF615 PF04751.9 CCH63020.1 - 0.11 12.1 0.9 1.4 8.5 0.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF615) AAA_13 PF13166.1 CCH63020.1 - 0.13 10.6 1.2 0.16 10.4 0.8 1.0 1 0 0 1 1 1 0 AAA domain NPV_P10 PF05531.7 CCH63020.1 - 0.84 9.9 5.9 8.7 6.6 0.3 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 CCH63020.1 - 3.8 7.3 7.1 7.5 6.3 4.1 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.17 CCH63021.1 - 1.5e-55 187.0 0.0 1.8e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCH63021.1 - 5.7e-16 59.0 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCH63021.1 - 3.8e-07 29.5 0.0 5.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCH63021.1 - 0.00027 20.4 0.0 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCH63021.1 - 0.0041 16.2 0.0 0.0055 15.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCH63021.1 - 0.063 12.4 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fmp27_WPPW PF10359.4 CCH63022.1 - 1.4e-100 336.9 1.2 1.4e-100 336.9 0.9 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.4 CCH63022.1 - 7.2e-94 315.1 75.0 1.5e-93 314.1 52.0 1.5 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 CCH63022.1 - 3e-76 257.1 20.8 2.8e-53 181.4 4.8 3.7 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CCH63022.1 - 4.2e-57 192.4 1.0 1.1e-56 191.0 0.7 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCH63022.1 - 9.1e-49 165.2 4.8 1.7e-48 164.3 1.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCH63022.1 - 1.1e-30 106.1 0.4 1.6e-29 102.3 0.1 3.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain RRM_1 PF00076.17 CCH63023.1 - 3.3e-06 26.6 0.0 6.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH63023.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ORC4_C PF14629.1 CCH63024.1 - 4.6e-33 114.3 2.4 9.5e-33 113.3 1.6 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CCH63024.1 - 1.5e-06 28.3 0.0 4.6e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCH63024.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CCH63024.1 - 0.021 15.0 2.8 0.031 14.4 0.2 2.7 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pneumo_matrix PF03393.11 CCH63024.1 - 0.021 13.7 0.9 0.13 11.1 0.3 2.4 2 1 0 2 2 2 0 Pneumovirus matrix protein Pkinase PF00069.20 CCH63025.1 - 2e-72 243.5 0.1 5.5e-72 242.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH63025.1 - 2e-30 105.7 0.0 9.6e-30 103.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 CCH63026.1 - 3.1e-14 53.0 0.1 5.4e-09 36.1 0.0 2.8 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 CCH63026.1 - 9.6e-09 34.8 0.1 2.7e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 CCH63027.1 - 1e-38 132.6 0.0 1.7e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CCH63027.1 - 5e-36 122.6 0.3 1.1e-35 121.5 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CCH63027.1 - 1.9e-11 43.9 0.6 6.6e-11 42.1 0.4 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCH63027.1 - 0.0065 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCH63027.1 - 0.082 12.7 0.0 0.9 9.3 0.0 2.6 3 0 0 3 3 3 0 Dynamin family MFS_1 PF07690.11 CCH63028.1 - 2.1e-25 89.2 27.1 7.5e-16 57.7 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCH63028.1 - 1.2e-10 40.3 21.3 6.6e-07 28.0 7.4 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 CCH63028.1 - 1.2e-06 27.4 0.7 1.2e-06 27.4 0.5 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 CCH63028.1 - 0.0059 14.7 7.7 0.22 9.6 0.8 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector OATP PF03137.15 CCH63028.1 - 0.0077 14.3 9.1 0.092 10.7 0.7 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S26 PF10502.4 CCH63028.1 - 0.093 12.2 0.1 0.34 10.4 0.0 1.9 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 Ribosomal_S7 PF00177.16 CCH63029.1 - 1.2e-39 135.2 1.9 1.6e-39 134.8 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Baculo_IE-1 PF05290.6 CCH63029.1 - 0.08 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) GCV_T PF01571.16 CCH63030.1 - 0.00016 21.1 0.0 0.81 9.0 0.0 3.0 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCH63030.1 - 0.037 14.0 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DnaB_2 PF07261.6 CCH63030.1 - 0.04 13.5 0.1 0.54 9.8 0.0 2.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment JmjC PF02373.17 CCH63031.1 - 9.6e-36 122.4 1.4 1.4e-35 121.9 0.2 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 CCH63031.1 - 4.7e-14 51.6 0.3 1.2e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 CCH63031.1 - 5.6e-11 41.9 2.9 5.6e-11 41.9 2.0 2.4 2 0 0 2 2 2 1 PHD-finger MACPF PF01823.14 CCH63031.1 - 0.017 14.8 0.5 0.017 14.8 0.3 2.3 2 0 0 2 2 2 0 MAC/Perforin domain PHD_2 PF13831.1 CCH63031.1 - 0.54 9.6 3.9 0.26 10.6 0.3 2.3 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 CCH63031.1 - 0.87 9.3 4.0 0.41 10.4 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PfkB PF00294.19 CCH63032.1 - 1e-69 234.9 1.7 1.3e-69 234.6 1.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCH63032.1 - 3.3e-06 26.4 0.1 7e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Lipase_3 PF01764.20 CCH63033.1 - 3.7e-37 127.0 0.0 5.5e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CCH63033.1 - 0.026 13.9 0.1 5.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Esterase PF00756.15 CCH63033.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 CCH63033.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family G-alpha PF00503.15 CCH63034.1 - 9.8e-99 330.6 46.7 1.7e-85 287.1 9.6 3.9 1 1 2 3 3 3 2 G-protein alpha subunit Arf PF00025.16 CCH63034.1 - 3.9e-16 58.7 0.9 1e-10 41.1 0.3 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Daxx PF03344.10 CCH63034.1 - 0.00011 20.8 28.8 0.00011 20.8 20.0 2.2 2 0 0 2 2 2 2 Daxx Family Miro PF08477.8 CCH63034.1 - 0.0033 17.9 4.7 3 8.3 0.0 3.6 2 1 0 2 2 2 2 Miro-like protein DUF2890 PF11081.3 CCH63034.1 - 0.011 15.7 27.6 0.011 15.7 19.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2890) Trypan_PARP PF05887.6 CCH63034.1 - 2.8 7.7 28.3 6.7 6.5 19.6 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RNA_pol_Rpb8 PF03870.10 CCH63035.1 - 2.1e-45 154.3 0.1 2.3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF2407_C PF13373.1 CCH63036.1 - 1.6e-40 138.2 0.9 1.6e-40 138.2 0.6 1.9 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CCH63036.1 - 5.4e-20 71.3 0.3 1.1e-19 70.4 0.2 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Zn_clus PF00172.13 CCH63037.1 - 9e-06 25.4 6.7 1.9e-05 24.4 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 CCH63037.1 - 0.0005 19.8 0.0 0.0024 17.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 CCH63037.1 - 0.084 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain CtaG_Cox11 PF04442.9 CCH63038.1 - 1.6e-55 187.1 0.4 4.8e-55 185.5 0.0 1.9 2 1 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Lactonase PF10282.4 CCH63039.1 - 0.056 12.5 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller RNA_bind_2 PF10133.4 CCH63039.1 - 0.15 12.0 0.1 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted RNA-binding protein Ribosomal_L18p PF00861.17 CCH63040.1 - 5.9e-46 155.5 0.0 5.9e-46 155.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CCH63040.1 - 9.8e-33 112.5 3.9 9.8e-33 112.5 2.7 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 CCH63040.1 - 0.06 13.3 0.4 0.92 9.5 0.0 2.7 3 0 0 3 3 3 0 Threonine synthase N terminus RFC1 PF08519.7 CCH63041.1 - 2.3e-61 206.0 3.5 7.8e-61 204.3 0.6 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CCH63041.1 - 1.2e-11 44.9 0.0 6.3e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CCH63041.1 - 2.7e-10 40.2 0.0 1.1e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain AAA_17 PF13207.1 CCH63041.1 - 3.3e-06 27.9 0.7 0.00023 21.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain Rad17 PF03215.10 CCH63041.1 - 1.7e-05 23.7 0.1 0.00049 18.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCH63041.1 - 1.9e-05 24.7 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCH63041.1 - 0.0001 21.4 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CCH63041.1 - 0.00022 21.5 2.2 0.013 15.8 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CCH63041.1 - 0.00033 20.5 0.0 0.0012 18.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCH63041.1 - 0.00098 18.8 0.0 0.0041 16.8 0.0 2.1 1 1 1 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CCH63041.1 - 0.0028 17.6 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 CCH63041.1 - 0.0061 16.7 0.0 0.025 14.7 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 CCH63041.1 - 0.0069 16.2 0.0 0.035 14.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCH63041.1 - 0.037 13.7 0.0 0.34 10.5 0.0 2.3 1 1 0 1 1 1 0 NACHT domain GRAB PF10375.4 CCH63042.1 - 2.2e-07 30.2 5.6 6e-07 28.8 1.1 2.7 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Cortex-I_coil PF09304.5 CCH63042.1 - 7.8e-05 22.6 12.5 7.8e-05 22.6 8.6 4.8 2 1 2 4 4 3 1 Cortexillin I, coiled coil Nup88 PF10168.4 CCH63042.1 - 0.0016 16.4 18.4 0.0016 16.4 12.8 2.4 1 1 0 2 2 2 1 Nuclear pore component AAA_13 PF13166.1 CCH63042.1 - 0.002 16.7 31.5 0.002 16.7 21.8 3.1 1 1 2 3 3 3 1 AAA domain DUF3450 PF11932.3 CCH63042.1 - 0.0031 16.8 7.5 0.0031 16.8 5.2 4.6 2 2 1 4 4 4 1 Protein of unknown function (DUF3450) IncA PF04156.9 CCH63042.1 - 0.026 14.1 74.1 0.12 11.9 17.0 4.6 1 1 3 4 4 4 0 IncA protein bZIP_1 PF00170.16 CCH63042.1 - 0.095 12.6 58.4 0.11 12.5 5.2 7.3 6 1 1 7 7 7 0 bZIP transcription factor FUSC PF04632.7 CCH63042.1 - 0.69 8.2 2.7 5.7 5.2 0.3 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Tropomyosin PF00261.15 CCH63042.1 - 1.7 7.7 65.4 0.037 13.1 26.2 3.3 2 1 1 3 3 3 0 Tropomyosin Atg14 PF10186.4 CCH63042.1 - 1.7 7.5 61.5 0.057 12.3 7.3 4.1 1 1 3 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CCH63042.1 - 1.8 6.9 60.6 0.013 13.9 8.3 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF342) ADIP PF11559.3 CCH63042.1 - 2.1 8.2 69.3 0.058 13.2 14.0 4.4 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding TMF_TATA_bd PF12325.3 CCH63042.1 - 2.2 8.0 69.6 0.016 14.9 9.4 5.6 1 1 4 5 5 5 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 CCH63042.1 - 2.5 7.9 71.8 0.11 12.3 10.4 4.3 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 CCH63042.1 - 2.5 6.2 67.5 1.2 7.2 42.9 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Spc7 PF08317.6 CCH63042.1 - 2.7 6.5 74.1 0.61 8.6 20.2 3.8 1 1 3 4 4 4 0 Spc7 kinetochore protein Acetyltransf_7 PF13508.1 CCH63043.1 - 0.036 14.2 0.0 0.07 13.2 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain YqeY PF09424.5 CCH63044.1 - 1.1e-20 73.9 11.1 1.1e-20 73.9 7.7 1.5 1 1 1 2 2 2 1 Yqey-like protein 5_3_exonuc_N PF02739.11 CCH63044.1 - 0.035 13.4 4.1 0.51 9.6 1.1 2.1 1 1 1 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain tRNA_NucTran2_2 PF13735.1 CCH63044.1 - 0.075 12.8 5.5 0.18 11.5 3.7 1.8 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative GerE PF00196.14 CCH63044.1 - 0.28 10.5 1.9 0.34 10.2 0.3 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family DUF1764 PF08576.5 CCH63044.1 - 6.2 7.6 7.5 2.6 8.8 3.4 1.7 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) YEATS PF03366.11 CCH63045.1 - 4.4e-20 71.1 0.1 8.9e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 YEATS family TRF PF08558.5 CCH63046.1 - 3.2e-18 65.9 10.5 6.7e-17 61.6 7.3 2.4 1 1 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 CCH63046.1 - 1.4e-05 25.0 0.5 2.7e-05 24.1 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH63046.1 - 0.00079 19.4 0.2 0.0029 17.6 0.2 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain IBN_N PF03810.14 CCH63047.1 - 1e-16 60.5 1.2 5.1e-15 55.1 0.3 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Mog1 PF04603.7 CCH63047.1 - 0.0032 17.4 0.1 0.0092 15.9 0.0 1.8 1 0 0 1 1 1 1 Ran-interacting Mog1 protein ANTH PF07651.11 CCH63048.1 - 0.00037 19.3 2.7 0.00052 18.8 1.9 1.1 1 0 0 1 1 1 1 ANTH domain DUF1754 PF08555.5 CCH63048.1 - 2 9.0 4.2 0.62 10.6 0.2 2.1 2 1 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Ribonuclease_T2 PF00445.13 CCH63049.1 - 5.2e-41 140.3 3.7 1.1e-40 139.3 2.5 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family Nop52 PF05997.7 CCH63050.1 - 9.2e-66 221.3 2.3 1.1e-65 221.1 1.6 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3139 PF11337.3 CCH63050.1 - 0.061 13.6 0.2 0.47 10.7 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) RXT2_N PF08595.6 CCH63050.1 - 0.13 12.0 1.2 0.36 10.6 0.8 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 CCH63050.1 - 2.5 7.5 7.4 0.15 11.5 1.3 1.8 2 0 0 2 2 2 0 Nucleoplasmin SecE PF00584.15 CCH63051.1 - 6.3e-11 41.6 0.0 7e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CBFD_NFYB_HMF PF00808.18 CCH63052.1 - 1.5e-11 44.1 0.0 2.3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Oxidored_FMN PF00724.15 CCH63053.1 - 1.3e-118 395.9 0.0 1.4e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TENA_THI-4 PF03070.11 CCH63054.1 - 5.2e-07 29.6 6.1 7.6e-07 29.0 4.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family CRAL_TRIO_2 PF13716.1 CCH63056.1 - 1.2e-29 103.1 3.6 3.2e-29 101.7 2.5 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CCH63056.1 - 2e-12 47.0 0.3 2.3e-11 43.5 0.2 2.6 1 1 0 1 1 1 1 RhoGAP domain SEF14_adhesin PF06443.6 CCH63056.1 - 0.071 12.7 0.4 0.17 11.5 0.3 1.6 1 0 0 1 1 1 0 SEF14-like adhesin RasGEF PF00617.14 CCH63057.1 - 2e-52 177.6 3.7 2e-52 177.6 2.6 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCH63057.1 - 1.7e-14 53.8 0.8 1.7e-14 53.8 0.6 3.1 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.23 CCH63057.1 - 0.0012 18.2 0.1 0.0031 16.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain Aconitase PF00330.15 CCH63058.1 - 1.9e-152 507.9 0.0 3.6e-152 507.1 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCH63058.1 - 8.8e-39 132.6 0.0 2e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CCH63058.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) SPX PF03105.14 CCH63059.1 - 6e-36 124.6 29.4 2.4e-35 122.6 20.4 2.0 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CCH63059.1 - 1.9e-17 63.3 37.8 3e-17 62.6 26.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCH63059.1 - 6.1e-10 38.1 19.5 6.1e-10 38.1 13.5 2.1 1 1 1 2 2 2 1 Citrate transporter UCH PF00443.24 CCH63060.1 - 2.8e-87 292.2 3.7 1.3e-85 286.7 0.9 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCH63060.1 - 1.5e-17 63.9 18.9 1.5e-10 41.0 1.8 4.4 4 2 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase PfkB PF00294.19 CCH63061.1 - 3.8e-50 170.7 0.2 8.6e-50 169.5 0.1 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.13 CCH63062.1 - 2.1e-08 33.9 9.9 4.5e-08 32.8 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2797 PF10977.3 CCH63062.1 - 0.26 10.8 2.1 0.62 9.6 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Glutaredoxin PF00462.19 CCH63062.1 - 1.9 8.5 5.0 4 7.4 0.1 2.9 3 0 0 3 3 3 0 Glutaredoxin AAA PF00004.24 CCH63064.1 - 2.9e-98 325.1 0.0 4.7e-48 162.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCH63064.1 - 2.8e-19 68.8 0.7 8.2e-19 67.3 0.5 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CCH63064.1 - 7.8e-14 51.9 0.1 2.9e-07 30.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCH63064.1 - 2.7e-13 49.5 0.0 1.5e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCH63064.1 - 4.2e-13 49.2 0.5 2.1e-06 27.5 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCH63064.1 - 6.1e-12 45.9 0.0 0.00041 20.3 0.0 3.7 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CCH63064.1 - 7e-12 45.4 0.1 4.9e-06 26.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CCH63064.1 - 3.4e-11 43.9 0.1 0.0013 19.5 0.0 3.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CCH63064.1 - 6.9e-11 42.3 3.0 0.0013 18.9 0.1 4.8 3 2 0 3 3 3 2 AAA domain TIP49 PF06068.8 CCH63064.1 - 2.7e-09 36.2 0.1 0.0012 17.6 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCH63064.1 - 1.6e-08 34.5 0.0 0.0041 17.0 0.0 3.3 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 CCH63064.1 - 7.5e-08 31.9 0.1 0.0074 15.7 0.0 3.1 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CCH63064.1 - 2e-07 30.6 1.1 0.021 14.5 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CCH63064.1 - 2e-07 31.1 0.0 0.01 15.9 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CCH63064.1 - 2.2e-07 30.4 6.1 0.0084 15.5 0.3 4.2 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CCH63064.1 - 2.8e-07 29.9 0.4 0.022 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 CCH63064.1 - 3e-07 29.9 0.0 7.7e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 CCH63064.1 - 4.6e-07 29.1 0.0 0.011 14.8 0.0 2.9 2 1 0 2 2 2 2 Zeta toxin AAA_24 PF13479.1 CCH63064.1 - 2.2e-06 27.3 0.1 0.11 12.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 CCH63064.1 - 3.3e-06 26.3 3.1 0.31 10.1 0.0 3.8 2 2 2 4 4 4 2 KaiC AAA_28 PF13521.1 CCH63064.1 - 3.7e-06 26.9 0.5 0.25 11.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 CCH63064.1 - 8.2e-06 25.7 0.2 0.0099 15.7 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 CCH63064.1 - 1.2e-05 24.3 0.0 0.13 11.1 0.0 3.0 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 CCH63064.1 - 1.2e-05 25.5 0.0 0.2 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CCH63064.1 - 1.4e-05 24.6 0.1 0.14 11.6 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CCH63064.1 - 3.3e-05 24.2 0.1 0.098 12.9 0.0 3.8 3 1 0 3 3 2 1 ABC transporter PhoH PF02562.11 CCH63064.1 - 3.8e-05 23.0 2.5 0.11 11.7 0.0 3.1 3 0 0 3 3 3 2 PhoH-like protein Bac_DnaA PF00308.13 CCH63064.1 - 4e-05 23.3 0.0 0.19 11.3 0.0 3.4 3 0 0 3 3 3 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 CCH63064.1 - 4.6e-05 23.4 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.1 CCH63064.1 - 5.2e-05 22.9 0.0 0.43 10.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 CCH63064.1 - 6.5e-05 21.9 0.0 0.09 11.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Vps4_C PF09336.5 CCH63064.1 - 8.8e-05 22.3 0.4 0.00097 18.9 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 CCH63064.1 - 9e-05 22.0 0.0 0.68 9.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCH63064.1 - 0.00024 20.8 0.1 1.7 8.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Arch_ATPase PF01637.13 CCH63064.1 - 0.00038 20.2 3.6 0.65 9.6 0.0 4.4 4 2 1 5 5 4 2 Archaeal ATPase AAA_30 PF13604.1 CCH63064.1 - 0.00051 19.6 0.0 1.7 8.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CCH63064.1 - 0.00052 19.0 0.0 0.71 8.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 CCH63064.1 - 0.0062 15.4 0.1 1.9 7.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.11 CCH63064.1 - 0.015 14.4 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NTPase_1 PF03266.10 CCH63064.1 - 0.018 14.7 1.4 3.4 7.3 0.0 3.8 4 0 0 4 4 3 0 NTPase Zot PF05707.7 CCH63064.1 - 0.025 14.0 0.3 5.7 6.3 0.1 3.6 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 CCH63064.1 - 0.06 12.9 0.1 7.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 CCH63064.1 - 0.064 12.2 2.8 1.7 7.5 0.0 3.2 3 2 1 4 4 3 0 KAP family P-loop domain Molydop_binding PF01568.16 CCH63064.1 - 0.074 12.8 0.1 0.33 10.8 0.0 2.1 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Viral_helicase1 PF01443.13 CCH63064.1 - 0.16 11.5 0.1 16 4.9 0.0 3.2 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase Cyclin_N PF00134.18 CCH63065.1 - 3.1e-15 55.8 0.1 7.1e-15 54.6 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCH63065.1 - 5.4e-09 36.6 0.1 5.4e-09 36.6 0.1 1.9 2 1 0 2 2 2 1 Cyclin Na_Ca_ex PF01699.19 CCH63066.1 - 5.8e-52 175.0 30.5 3.4e-26 91.5 5.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Flavoprotein PF02441.14 CCH63066.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Flavoprotein HNF-1_N PF04814.8 CCH63068.1 - 0.025 14.6 1.6 5.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Methyltransf_31 PF13847.1 CCH63068.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FBPase_2 PF06874.6 CCH63068.1 - 0.042 11.8 0.6 0.065 11.2 0.4 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Methyltransf_11 PF08241.7 CCH63068.1 - 0.096 13.1 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SNARE PF05739.14 CCH63069.1 - 3.3e-12 45.9 11.4 3.3e-12 45.8 0.7 3.8 3 1 1 4 4 4 1 SNARE domain FliJ PF02050.11 CCH63069.1 - 0.01 15.8 4.8 0.01 15.8 3.3 2.5 2 1 0 2 2 2 0 Flagellar FliJ protein MIS13 PF08202.6 CCH63069.1 - 0.013 14.5 11.7 0.018 14.1 8.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family TMPIT PF07851.8 CCH63069.1 - 0.014 14.4 5.7 0.014 14.4 0.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein Laminin_II PF06009.7 CCH63069.1 - 0.017 14.8 10.5 0.8 9.4 1.8 3.0 2 1 1 3 3 3 0 Laminin Domain II NPV_P10 PF05531.7 CCH63069.1 - 0.023 14.9 0.6 0.023 14.9 0.4 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 CCH63069.1 - 0.05 13.9 12.4 7.1 7.0 0.1 4.2 2 2 2 4 4 4 0 SlyX Allexi_40kDa PF05549.6 CCH63069.1 - 0.07 12.4 11.2 0.029 13.6 4.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Hpt PF01627.18 CCH63069.1 - 0.086 12.8 1.1 6.5 6.8 0.6 2.7 2 1 0 2 2 2 0 Hpt domain Cob_adeno_trans PF01923.13 CCH63069.1 - 0.11 12.2 5.1 0.5 10.1 0.4 2.4 1 1 0 2 2 2 0 Cobalamin adenosyltransferase Prominin PF05478.6 CCH63069.1 - 0.17 9.4 11.8 0.16 9.4 3.4 2.0 1 1 1 2 2 2 0 Prominin DUF745 PF05335.8 CCH63069.1 - 0.33 10.4 8.1 0.92 8.9 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.7 CCH63069.1 - 0.38 10.5 10.8 4.1 7.1 0.6 2.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 CCH63069.1 - 0.38 10.0 4.6 0.86 8.9 0.0 2.8 1 1 2 3 3 3 0 PspA/IM30 family WEMBL PF05701.6 CCH63069.1 - 0.4 9.0 5.0 0.77 8.1 3.5 1.6 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DivIVA PF05103.8 CCH63069.1 - 0.72 9.9 8.9 0.26 11.3 2.4 2.3 1 1 0 2 2 2 0 DivIVA protein DUF1664 PF07889.7 CCH63069.1 - 0.76 9.5 7.6 5.2 6.8 2.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.6 CCH63069.1 - 0.83 10.0 15.0 3.5 8.1 1.4 4.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF16 PF01519.11 CCH63069.1 - 1 9.5 10.7 4.4 7.5 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 E2R135 PF11570.3 CCH63069.1 - 1.7 8.7 4.4 2 8.4 1.4 2.1 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 GvpK PF05121.7 CCH63069.1 - 2.9 7.7 6.2 5.7 6.8 0.1 2.9 2 1 1 3 3 3 0 Gas vesicle protein K DASH_Dad1 PF08649.5 CCH63069.1 - 3 7.5 6.5 7.2 6.3 0.6 3.1 4 0 0 4 4 4 0 DASH complex subunit Dad1 Fzo_mitofusin PF04799.8 CCH63069.1 - 3.3 7.0 8.8 29 4.0 2.8 2.9 1 1 1 2 2 2 0 fzo-like conserved region IL3 PF02059.10 CCH63069.1 - 3.7 7.5 8.9 1.2 9.0 3.8 1.9 1 1 1 2 2 2 0 Interleukin-3 V_ATPase_I PF01496.14 CCH63069.1 - 9.9 3.8 8.4 17 3.0 5.9 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DDHD PF02862.12 CCH63071.1 - 1.3e-42 146.1 0.5 2.5e-25 89.5 0.0 3.3 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.10 CCH63071.1 - 9.7e-06 24.7 1.2 0.00083 18.4 0.0 2.9 2 1 1 3 3 3 2 Lecithin:cholesterol acyltransferase RNA_Me_trans PF04252.8 CCH63072.1 - 1.4e-79 266.1 0.0 1.5e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF2611 PF11022.3 CCH63073.1 - 7.9e-18 64.3 0.1 9e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Cpn10 PF00166.16 CCH63074.1 - 2.3e-25 88.3 0.3 2.6e-25 88.1 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit eIF-1a PF01176.14 CCH63074.1 - 0.083 12.3 0.1 0.4 10.1 0.0 2.1 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 SIR2 PF02146.12 CCH63076.1 - 2.4e-37 128.3 0.3 3.5e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Sir2 family FYVE_2 PF02318.11 CCH63076.1 - 0.0077 16.1 0.6 0.0077 16.1 0.4 2.1 2 0 0 2 2 2 1 FYVE-type zinc finger IncA PF04156.9 CCH63076.1 - 0.77 9.3 5.6 14 5.1 1.6 2.3 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 CCH63077.1 - 1.8e-10 40.6 9.2 3.1e-10 39.8 6.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 CCH63077.1 - 0.013 15.2 1.8 0.026 14.2 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.12 CCH63077.1 - 0.22 11.8 4.4 0.43 10.8 3.1 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.10 CCH63077.1 - 5.4 6.9 10.2 13 5.7 7.0 1.6 1 1 0 1 1 1 0 Basic region leucine zipper Cellulase PF00150.13 CCH63078.1 - 8.4e-13 48.1 25.7 5.5e-12 45.4 17.8 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fasciclin PF02469.17 CCH63079.1 - 0.00014 21.8 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain EPV_E5 PF08135.6 CCH63079.1 - 0.0065 16.4 2.0 0.011 15.7 1.4 1.3 1 0 0 1 1 1 1 Major transforming protein E5 family VPS11_C PF12451.3 CCH63079.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal Sbi-IV PF11621.3 CCH63079.1 - 0.35 11.0 0.1 0.35 11.0 0.0 2.4 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI HLH PF00010.21 CCH63080.1 - 1.8e-16 59.5 1.5 3e-16 58.8 1.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRP38_assoc PF12871.2 CCH63080.1 - 3.1 8.4 15.3 4.6 7.8 5.8 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ank_2 PF12796.2 CCH63081.1 - 1.4e-53 179.1 0.1 1.5e-18 66.9 0.1 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCH63081.1 - 5.4e-34 114.3 0.1 4.1e-09 35.7 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CCH63081.1 - 2.8e-26 91.3 1.6 4.1e-09 36.7 0.1 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCH63081.1 - 2.2e-25 88.0 0.2 2.3e-07 30.8 0.1 5.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CCH63081.1 - 8.3e-24 83.9 3.2 8.3e-24 83.9 2.3 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_3 PF13606.1 CCH63081.1 - 1.5e-23 80.5 0.1 6.5e-05 22.8 0.1 6.5 6 0 0 6 6 6 4 Ankyrin repeat ENTH PF01417.15 CCH63081.1 - 0.0054 16.5 0.0 12 5.7 0.0 3.5 2 1 1 3 3 3 1 ENTH domain UNC45-central PF11701.3 CCH63082.1 - 2e-24 86.0 0.1 1e-23 83.7 0.1 2.4 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Lactamase_B PF00753.22 CCH63083.1 - 3.3e-19 69.2 0.0 6.3e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCH63083.1 - 8.2e-05 22.2 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TOMM6 PF15184.1 CCH63085.1 - 0.25 10.6 0.2 0.25 10.6 0.1 1.7 2 1 0 3 3 3 0 Mitochondrial import receptor subunit TOM6 homolog Pmp3 PF01679.12 CCH63086.1 - 1.8e-17 62.7 7.8 1.9e-17 62.6 5.4 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.7 CCH63086.1 - 0.027 14.2 2.9 0.033 13.9 2.0 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DEAD PF00270.24 CCH63087.1 - 5.4e-35 120.3 0.7 5.4e-35 120.3 0.5 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCH63087.1 - 4.9e-27 93.5 0.1 1.3e-26 92.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain YhfZ_C PF14503.1 CCH63087.1 - 0.0045 16.3 0.9 0.12 11.7 0.2 2.4 1 1 1 2 2 2 1 YhfZ C-terminal domain Helicase_C_2 PF13307.1 CCH63087.1 - 0.0087 16.0 0.4 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain Vfa1 PF08432.5 CCH63087.1 - 0.15 12.0 9.1 0.24 11.4 6.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RAP PF08373.5 CCH63088.1 - 0.021 14.6 0.2 0.021 14.6 0.1 2.0 2 0 0 2 2 2 0 RAP domain Orthopox_F14 PF06076.7 CCH63088.1 - 0.1 12.6 0.3 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Orthopoxvirus F14 protein Acyltransferase PF01553.16 CCH63089.1 - 9.9e-07 28.2 0.0 2.4e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Roughex PF06020.6 CCH63089.1 - 0.039 12.6 0.1 0.23 10.0 0.2 1.9 2 0 0 2 2 2 0 Drosophila roughex protein Nro1 PF12753.2 CCH63090.1 - 4.1e-115 384.9 23.6 4.6e-115 384.7 16.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 zf-AN1 PF01428.11 CCH63091.1 - 6.7e-10 38.6 10.5 1.2e-09 37.8 7.3 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Flavoprotein PF02441.14 CCH63092.1 - 1.7e-42 144.1 0.0 7.4e-42 142.0 0.0 2.2 1 1 0 1 1 1 1 Flavoprotein SGS PF05002.10 CCH63093.1 - 1.8e-28 98.1 0.9 1.8e-28 98.1 0.6 2.1 3 0 0 3 3 3 1 SGS domain CS PF04969.11 CCH63093.1 - 3.6e-14 53.0 2.4 7.5e-14 52.0 1.7 1.6 1 0 0 1 1 1 1 CS domain ABC_sub_bind PF04392.7 CCH63093.1 - 0.052 12.4 1.3 0.53 9.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter substrate binding protein MAP65_ASE1 PF03999.7 CCH63094.1 - 3.8e-54 184.3 57.1 8.4e-54 183.2 38.3 2.5 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) DnaJ PF00226.26 CCH63095.1 - 2.8e-18 65.4 0.2 7.8e-18 63.9 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain DUF2121 PF09894.4 CCH63095.1 - 0.32 10.2 4.6 0.15 11.3 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) MFS_1 PF07690.11 CCH63096.1 - 8.4e-25 87.2 14.3 1.3e-24 86.6 9.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2930 PF11152.3 CCH63096.1 - 0.042 13.0 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) Pkinase PF00069.20 CCH63097.1 - 2.1e-44 151.6 0.0 3.9e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH63097.1 - 1.1e-16 60.6 0.0 2.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCH63098.1 - 4.8e-40 137.3 0.1 5.5e-27 94.5 0.2 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCH63098.1 - 1.3e-19 70.2 0.0 9.3e-16 57.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCH63098.1 - 0.013 14.5 0.0 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Zip PF02535.17 CCH63099.1 - 7.3e-21 74.4 16.2 4e-20 72.0 4.5 3.4 1 1 0 2 2 2 1 ZIP Zinc transporter GST_C PF00043.20 CCH63100.1 - 1.6e-06 28.0 0.0 3.3e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCH63100.1 - 3.5e-06 26.8 0.0 5.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCH63100.1 - 0.00058 20.2 0.0 0.00099 19.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCH63101.1 - 5.4e-08 32.7 0.0 9.5e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCH63101.1 - 5.5e-05 22.9 0.2 9.3e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SET PF00856.23 CCH63102.1 - 2.1e-24 86.6 0.3 2.1e-24 86.6 0.2 3.5 3 2 0 3 3 3 1 SET domain SRI PF08236.6 CCH63102.1 - 1.2e-19 69.9 6.5 1.2e-19 69.9 4.5 2.3 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 CCH63102.1 - 0.0013 18.4 0.1 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 WW domain DUF2976 PF11190.3 CCH63103.1 - 0.004 16.6 0.1 1.5 8.3 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2976) BPD_transp_1 PF00528.17 CCH63103.1 - 0.025 14.0 0.0 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF2401 PF10287.4 CCH63104.1 - 2.9e-74 249.4 1.6 3.8e-74 249.1 1.1 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCH63104.1 - 1.4e-22 79.6 0.1 3.2e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) STE3 PF02076.10 CCH63105.1 - 1.1e-94 316.6 25.3 1.4e-94 316.3 17.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor KRE9 PF05390.6 CCH63106.1 - 1.5e-42 144.3 4.3 1.5e-42 144.3 3.0 2.1 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCH63106.1 - 6.8e-10 39.2 0.5 6.8e-10 39.2 0.4 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SWIRM PF04433.12 CCH63107.1 - 1.7e-29 101.7 0.1 5.7e-29 100.0 0.1 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CCH63107.1 - 7.6e-11 41.9 0.9 7.6e-11 41.9 0.6 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH63107.1 - 4.4e-09 36.3 0.0 1.6e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ATG27 PF09451.5 CCH63108.1 - 2.8e-28 98.9 2.7 4.3e-28 98.3 1.9 1.3 1 1 0 1 1 1 1 Autophagy-related protein 27 Prefoldin_2 PF01920.15 CCH63110.1 - 1.2e-18 66.8 9.9 1.4e-18 66.6 6.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1699 PF08004.6 CCH63110.1 - 0.016 14.7 0.2 0.044 13.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1699) CST-I PF06002.7 CCH63110.1 - 0.1 11.8 1.9 0.11 11.7 0.6 1.5 1 1 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) ORF6C PF10552.4 CCH63110.1 - 0.36 10.5 5.6 0.14 11.9 1.0 1.9 1 1 1 2 2 2 0 ORF6C domain RasGAP_C PF03836.10 CCH63110.1 - 0.53 9.9 10.4 1.3 8.7 2.4 2.2 2 0 0 2 2 2 0 RasGAP C-terminus ACCA PF03255.9 CCH63110.1 - 0.66 9.5 6.5 0.49 9.9 1.9 1.9 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMF_DNA_bd PF12329.3 CCH63110.1 - 0.68 9.7 17.9 0.21 11.4 2.8 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CCH63110.1 - 0.98 8.9 12.2 2.4 7.6 0.9 2.3 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 CCH63110.1 - 1.1 7.8 10.7 1.5 7.3 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3338 PF11819.3 CCH63110.1 - 1.4 8.3 6.0 0.62 9.5 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) DUF4208 PF13907.1 CCH63110.1 - 2.3 8.4 7.1 0.98 9.6 0.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF3573 PF12097.3 CCH63110.1 - 3 6.3 6.1 3.4 6.1 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Syntaxin-6_N PF09177.6 CCH63110.1 - 5.5 7.4 7.7 1.8 9.0 1.7 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATP12 PF07542.6 CCH63111.1 - 9.8e-21 73.9 0.0 4.1e-20 71.9 0.0 2.0 1 1 0 1 1 1 1 ATP12 chaperone protein Glyco_transf_34 PF05637.7 CCH63113.1 - 7.4e-29 100.9 4.2 1e-28 100.4 2.9 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Gon7 PF08738.5 CCH63114.1 - 2.6e-32 110.8 0.2 3.1e-32 110.6 0.1 1.1 1 0 0 1 1 1 1 Gon7 family muHD PF10291.4 CCH63115.1 - 4.7e-63 212.7 0.1 7.4e-63 212.1 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mannosyl_trans3 PF11051.3 CCH63116.1 - 6.5e-77 258.5 0.0 1e-76 257.8 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.20 CCH63117.1 - 5.8e-42 143.6 0.6 8.9e-41 139.7 0.3 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCH63117.1 - 1.8e-26 92.7 0.0 3.3e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S11 PF00411.14 CCH63118.1 - 1.5e-40 137.7 0.8 1.9e-40 137.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Myb_DNA-binding PF00249.26 CCH63119.1 - 3.6e-14 52.5 0.0 9.7e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCH63119.1 - 2e-05 24.6 3.3 0.0054 16.8 0.1 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain ELO PF01151.13 CCH63120.1 - 2.5e-57 194.0 22.4 3.2e-57 193.6 15.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.16 CCH63121.1 - 5e-19 68.9 0.1 1.8e-18 67.1 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 zf-CCHC PF00098.18 CCH63122.1 - 1.1e-08 34.5 32.9 0.00091 19.0 1.8 4.2 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.1 CCH63122.1 - 0.83 9.2 19.0 0.22 11.0 0.3 3.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCH63122.1 - 2 8.1 37.2 0.36 10.5 1.4 5.3 4 1 1 5 5 5 0 Zinc knuckle tRNA-synt_2b PF00587.20 CCH63123.1 - 3.7e-46 156.8 1.2 9.2e-46 155.5 0.9 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCH63123.1 - 1.7e-19 69.5 0.5 4.4e-19 68.2 0.4 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CCH63123.1 - 2.5e-13 49.6 0.0 5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CCH63123.1 - 1.5e-11 43.9 0.0 3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain GET2 PF08690.5 CCH63124.1 - 1.9e-72 244.0 0.1 2.2e-72 243.8 0.1 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 BING4CT PF08149.6 CCH63125.1 - 4.9e-36 122.1 0.1 1.8e-34 117.0 0.0 3.0 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 CCH63125.1 - 2.1e-07 30.5 0.1 1.8e-05 24.4 0.0 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat TPD PF14811.1 CCH63125.1 - 1.4 8.4 4.9 0.27 10.7 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif SPO22 PF08631.5 CCH63126.1 - 1.7e-45 155.2 4.3 1.7e-45 155.2 3.0 3.8 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like PIR PF00399.14 CCH63127.1 - 1.5e-23 81.2 41.4 8.4e-09 34.4 2.1 7.1 7 0 0 7 7 7 4 Yeast PIR protein repeat HORMA PF02301.13 CCH63128.1 - 7.4e-49 166.0 2.7 7.4e-49 166.0 1.9 1.6 2 0 0 2 2 2 1 HORMA domain Dpoe2NT PF12213.3 CCH63128.1 - 0.028 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal PHD_2 PF13831.1 CCH63128.1 - 0.12 11.6 5.9 0.4 10.0 4.1 1.9 1 0 0 1 1 1 0 PHD-finger Yos1 PF08571.5 CCH63129.1 - 8.7e-31 105.8 2.4 9.7e-31 105.7 1.7 1.0 1 0 0 1 1 1 1 Yos1-like Rod_cone_degen PF15201.1 CCH63129.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Progressive rod-cone degeneration LCCL PF03815.14 CCH63130.1 - 2.3e-07 30.7 0.1 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Ribonuc_red_lgC PF02867.10 CCH63131.1 - 2e-212 706.5 0.0 2.7e-212 706.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCH63131.1 - 5.1e-22 77.4 0.0 1.4e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCH63131.1 - 4.3e-15 55.9 0.0 2.2e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain DUF619 PF04768.8 CCH63132.1 - 1.2e-38 132.2 0.3 2.8e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 CCH63132.1 - 3.4e-10 39.8 0.0 5.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family Pox_VLTF3 PF04947.9 CCH63132.1 - 0.027 13.9 1.7 0.096 12.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like zf-RING_4 PF14570.1 CCH63133.1 - 6.6e-20 70.4 13.0 1.2e-19 69.5 9.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 CCH63133.1 - 6.1e-07 29.2 5.6 0.001 18.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCH63133.1 - 8.2e-07 28.5 0.0 0.0022 17.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CCH63133.1 - 3.7e-06 26.5 6.8 7.2e-06 25.5 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CCH63133.1 - 0.00011 21.9 3.7 0.00011 21.9 2.6 2.4 2 1 0 2 2 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.1 CCH63133.1 - 0.00014 21.6 8.6 0.00028 20.6 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 CCH63133.1 - 0.00023 20.4 3.6 0.00023 20.4 2.5 4.5 4 1 1 5 5 4 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 CCH63133.1 - 0.0012 18.3 10.6 0.0029 17.2 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 CCH63133.1 - 0.0034 16.6 0.1 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_6 PF14259.1 CCH63133.1 - 0.013 15.4 0.1 0.5 10.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CCH63133.1 - 0.05 13.6 10.3 0.099 12.6 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCH63133.1 - 0.14 11.8 9.8 0.33 10.7 6.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCH63133.1 - 2.7 7.9 10.5 14 5.6 7.3 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2578 PF10843.3 CCH63134.1 - 2.7e-57 193.5 18.7 3e-57 193.4 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) RNase_PH PF01138.16 CCH63134.1 - 0.13 12.5 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 SAP PF02037.22 CCH63135.1 - 7.2e-13 47.6 0.0 1.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain HAD_2 PF13419.1 CCH63137.1 - 8.5e-12 45.6 0.0 1.1e-11 45.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCH63137.1 - 2.1e-06 28.3 0.0 4.8e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCH63137.1 - 2.8e-06 26.9 0.0 4.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCH63137.1 - 0.0034 17.5 0.0 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribonuc_L-PSP PF01042.16 CCH63138.1 - 4.8e-39 132.8 0.1 5.3e-39 132.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_L34e PF01199.13 CCH63139.1 - 4.3e-38 129.4 5.8 4.3e-38 129.4 4.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e DUF1428 PF07237.6 CCH63139.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Zn_ribbon_recom PF13408.1 CCH63139.1 - 0.17 12.1 2.0 0.42 10.9 1.4 1.8 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF3133 PF11331.3 CCH63139.1 - 0.36 10.4 1.9 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) FhuF_C PF11575.3 CCH63139.1 - 1.8 8.2 5.4 6.9 6.4 0.2 2.5 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Steroid_dh PF02544.11 CCH63140.1 - 2.8e-09 36.8 10.8 4.2e-09 36.3 6.4 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1385 PF07136.6 CCH63141.1 - 0.0013 17.8 1.6 0.73 8.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1385) E1-E2_ATPase PF00122.15 CCH63142.1 - 8.4e-28 96.9 0.1 1.7e-27 95.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCH63142.1 - 9.3e-14 52.3 0.1 2.4e-12 47.7 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCH63142.1 - 1.6e-10 41.5 0.0 4.5e-10 40.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCH63142.1 - 1e-07 31.7 0.0 4.6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCH63142.1 - 0.0037 16.8 0.1 0.03 13.8 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EXS PF03124.9 CCH63143.1 - 5.9e-82 275.4 28.1 9.6e-82 274.7 19.4 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCH63143.1 - 1.4e-26 93.9 1.9 8.1e-22 78.2 8.0 2.9 2 2 0 2 2 2 1 SPX domain CBM_21 PF03370.8 CCH63144.1 - 2.9e-26 91.6 1.8 6.6e-26 90.5 1.2 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit bZIP_2 PF07716.10 CCH63145.1 - 8.8e-07 28.6 10.9 2.9e-06 27.0 7.6 1.8 1 1 0 1 1 1 1 Basic region leucine zipper ATG16 PF08614.6 CCH63145.1 - 0.0022 17.8 5.0 0.0027 17.5 3.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 CCH63145.1 - 0.014 15.3 8.5 0.025 14.5 5.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor Sec16_N PF12935.2 CCH63145.1 - 0.058 13.2 1.4 0.071 12.9 0.9 1.1 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 N-terminus IncA PF04156.9 CCH63145.1 - 0.76 9.3 3.3 1.2 8.7 2.3 1.3 1 0 0 1 1 1 0 IncA protein Tim44 PF04280.10 CCH63146.1 - 1.6e-30 106.0 0.1 5.1e-30 104.3 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Glyco_hydro_20 PF00728.17 CCH63146.1 - 0.032 13.3 1.8 0.048 12.8 1.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain RNA_pol_A_bac PF01000.21 CCH63148.1 - 8.2e-32 109.6 0.3 2.8e-31 107.9 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCH63148.1 - 8.4e-14 50.4 0.0 1.5e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4611 PF15387.1 CCH63148.1 - 0.039 14.1 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GRP PF07172.6 CCH63148.1 - 0.095 13.1 8.4 0.15 12.5 5.8 1.3 1 0 0 1 1 1 0 Glycine rich protein family His_biosynth PF00977.16 CCH63149.1 - 8.6e-19 67.7 0.1 1.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein X PF00739.14 CCH63150.1 - 0.17 11.8 0.0 0.44 10.4 0.0 1.7 1 1 0 1 1 1 0 Trans-activation protein X HLH PF00010.21 CCH63151.1 - 2.2e-12 46.4 0.1 6.1e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tcell_CD4_Cterm PF12104.3 CCH63151.1 - 0.13 11.9 0.3 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region UCR_hinge PF02320.11 CCH63152.1 - 1.9e-23 82.1 6.2 2.8e-23 81.6 4.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Nop14 PF04147.7 CCH63152.1 - 0.0017 16.4 24.7 0.0018 16.3 17.1 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CCH63152.1 - 0.0019 16.3 14.4 0.0021 16.2 10.0 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 CCH63152.1 - 0.036 13.3 24.2 0.038 13.2 16.8 1.0 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 CCH63152.1 - 0.037 12.7 36.9 0.041 12.6 25.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop53 PF07767.6 CCH63152.1 - 0.039 12.9 8.9 0.049 12.6 6.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF506 PF04720.7 CCH63152.1 - 0.048 13.2 5.0 0.061 12.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Daxx PF03344.10 CCH63152.1 - 0.11 10.9 24.7 0.13 10.7 17.1 1.0 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 CCH63152.1 - 0.33 9.0 15.9 0.35 8.9 11.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-T PF15511.1 CCH63152.1 - 0.42 9.8 17.4 0.49 9.5 12.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Utp14 PF04615.8 CCH63152.1 - 0.84 7.7 16.2 0.96 7.5 11.2 1.1 1 0 0 1 1 1 0 Utp14 protein DUF2796 PF10986.3 CCH63152.1 - 0.92 9.4 12.2 1.2 9.1 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) HSP90 PF00183.13 CCH63152.1 - 3.7 5.8 15.8 4.4 5.5 10.9 1.1 1 0 0 1 1 1 0 Hsp90 protein SGT1 PF07093.6 CCH63152.1 - 4.1 5.6 18.0 4.6 5.5 12.4 1.1 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.10 CCH63152.1 - 9.1 4.7 7.0 9.5 4.7 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRM_1 PF00076.17 CCH63153.1 - 5.6e-15 54.7 0.3 8.1e-09 34.9 0.1 3.4 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH63153.1 - 2.4e-13 49.8 0.0 4.7e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH63153.1 - 1.1e-05 25.2 0.1 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SH3BGR PF04908.10 CCH63153.1 - 0.017 15.0 1.9 0.054 13.4 1.3 1.9 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ribosomal_L2_C PF03947.13 CCH63154.1 - 5.4e-41 139.4 2.4 8.4e-41 138.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCH63154.1 - 1e-14 54.2 0.1 2.3e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HEAT PF02985.17 CCH63155.1 - 0.031 14.3 0.0 0.3 11.2 0.0 2.9 1 0 0 1 1 1 0 HEAT repeat Steroid_dh PF02544.11 CCH63156.1 - 0.034 13.9 0.1 0.046 13.4 0.1 1.2 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Gly-zipper_OmpA PF13436.1 CCH63156.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Sedlin_N PF04628.8 CCH63158.1 - 5.8e-31 107.0 0.0 7.8e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCH63158.1 - 6.9e-05 22.5 0.1 0.00021 21.0 0.0 1.8 2 0 0 2 2 2 1 Sybindin-like family Med22 PF06179.7 CCH63159.1 - 9.5e-18 64.2 5.0 1.6e-17 63.4 3.5 1.4 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3126 PF11324.3 CCH63159.1 - 0.29 10.8 2.6 7.5 6.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3126) dUTPase PF00692.14 CCH63160.1 - 4.3e-44 149.1 0.0 5e-44 148.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase Ribosomal_S5 PF00333.15 CCH63161.1 - 1.3e-20 72.8 0.0 2.4e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCH63161.1 - 4.9e-20 70.5 0.0 1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HMG_box PF00505.14 CCH63162.1 - 9.2e-14 51.4 4.9 3.6e-13 49.5 3.4 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCH63162.1 - 0.00017 21.8 2.2 0.00076 19.7 0.7 2.3 1 1 1 2 2 2 1 HMG-box domain DEC-1_N PF04625.8 CCH63162.1 - 1.1 7.8 11.0 1.5 7.3 7.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NAD_binding_8 PF13450.1 CCH63163.1 - 3.3e-10 39.8 0.0 9.9e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 CCH63163.1 - 0.0027 15.9 0.0 0.0044 15.2 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.19 CCH63163.1 - 0.003 16.6 0.3 0.029 13.4 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 CCH63163.1 - 0.021 15.1 0.0 0.48 10.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCH63163.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCH63163.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCH63163.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gti1_Pac2 PF09729.4 CCH63164.1 - 3.3e-45 153.9 10.3 2.4e-40 138.1 0.0 3.3 2 2 1 3 3 3 2 Gti1/Pac2 family Thioredoxin PF00085.15 CCH63165.1 - 2.5e-20 72.0 3.1 3.5e-18 65.1 0.0 3.7 5 0 0 5 5 5 2 Thioredoxin TEX12 PF15219.1 CCH63166.1 - 0.0087 16.0 0.2 0.0087 16.0 0.2 2.8 2 1 1 3 3 3 1 Testis-expressed 12 AHS1 PF02682.11 CCH63166.1 - 0.36 10.2 3.0 0.4 10.1 0.1 2.3 2 1 1 3 3 3 0 Allophanate hydrolase subunit 1 Prefoldin_2 PF01920.15 CCH63167.1 - 3.3e-20 71.8 10.0 4e-20 71.5 6.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit ATP_bind_3 PF01171.15 CCH63167.1 - 0.012 15.0 0.2 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 PP-loop family Thymidylat_synt PF00303.14 CCH63167.1 - 0.037 13.0 0.5 0.043 12.8 0.3 1.2 1 0 0 1 1 1 0 Thymidylate synthase Prefoldin PF02996.12 CCH63167.1 - 0.055 13.1 5.2 0.32 10.6 0.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit Bap31 PF05529.7 CCH63167.1 - 0.092 12.1 3.9 0.12 11.8 2.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Takusan PF04822.8 CCH63167.1 - 0.15 11.8 4.2 0.56 9.9 2.9 1.8 1 1 0 1 1 1 0 Takusan HLH PF00010.21 CCH63167.1 - 0.16 11.7 1.3 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain 4HB_MCP_1 PF12729.2 CCH63167.1 - 0.19 11.0 4.9 0.89 8.8 0.1 2.0 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DASH_Dad3 PF08656.5 CCH63167.1 - 0.2 11.3 5.0 0.13 11.9 0.9 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad3 Atg14 PF10186.4 CCH63167.1 - 0.21 10.4 2.4 0.27 10.1 1.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_L25p PF01386.14 CCH63167.1 - 0.22 11.6 0.3 0.22 11.6 0.2 1.8 2 0 0 2 2 2 0 Ribosomal L25p family Spc24 PF08286.6 CCH63167.1 - 0.3 10.8 8.9 2.1 8.0 0.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Rad9 PF04139.8 CCH63167.1 - 0.32 10.0 2.6 2.3 7.2 0.2 2.0 1 1 1 2 2 2 0 Rad9 Fib_alpha PF08702.5 CCH63167.1 - 0.34 11.0 7.3 0.46 10.6 5.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 CCH63167.1 - 0.35 9.8 5.3 0.43 9.5 3.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Rep_3 PF01051.16 CCH63167.1 - 0.38 10.2 5.5 0.67 9.5 0.2 2.0 1 1 1 2 2 2 0 Initiator Replication protein DUF2935 PF11155.3 CCH63167.1 - 1.1 9.3 5.4 1.6 8.8 3.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) bZIP_1 PF00170.16 CCH63167.1 - 5.5 7.0 6.9 17 5.4 0.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor DDOST_48kD PF03345.9 CCH63168.1 - 2.1e-113 379.0 2.3 2.4e-113 378.8 1.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Nsp1_C PF05064.8 CCH63169.1 - 0.039 13.5 0.9 0.046 13.3 0.6 1.3 1 1 0 1 1 1 0 Nsp1-like C-terminal region Pox_Rif PF03340.8 CCH63169.1 - 0.051 11.6 0.1 0.055 11.5 0.1 1.0 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein APG6 PF04111.7 CCH63169.1 - 0.075 12.0 0.6 0.08 11.9 0.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 CCH63169.1 - 0.094 12.5 0.8 0.21 11.4 0.6 1.3 1 1 0 1 1 1 0 Tropomyosin like Laminin_II PF06009.7 CCH63169.1 - 0.1 12.3 0.5 0.11 12.2 0.3 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF16 PF01519.11 CCH63169.1 - 0.1 12.8 0.9 0.12 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 FlxA PF14282.1 CCH63169.1 - 0.35 10.8 4.1 0.43 10.5 2.8 1.3 1 0 0 1 1 1 0 FlxA-like protein AAA_23 PF13476.1 CCH63169.1 - 1.1 9.4 4.9 1.3 9.2 3.4 1.0 1 0 0 1 1 1 0 AAA domain Syja_N PF02383.13 CCH63170.1 - 6.7e-63 212.3 1.7 6.7e-63 212.3 1.2 1.8 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 CCH63170.1 - 1.4e-23 84.0 0.0 2.5e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.26 CCH63171.1 - 6.5e-19 67.9 4.3 4.7e-14 52.3 0.2 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.25 CCH63171.1 - 7e-10 38.2 0.1 7.4e-07 28.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCH63171.1 - 3.1e-09 37.0 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCH63171.1 - 4.2e-07 30.2 0.3 1.3e-05 25.5 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCH63171.1 - 1.5e-06 28.2 0.2 0.00097 19.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCH63171.1 - 3.7e-06 26.6 0.3 0.014 15.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat DUF3342 PF11822.3 CCH63171.1 - 0.58 9.2 5.7 10 5.1 3.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3342) SRP1_TIP1 PF00660.12 CCH63173.1 - 2.4e-34 117.2 1.2 2.4e-34 117.2 0.8 1.6 2 0 0 2 2 2 1 Seripauperin and TIP1 family Tmemb_cc2 PF10267.4 CCH63173.1 - 0.93 8.0 3.9 0.94 7.9 2.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 CCH63173.1 - 4.8 5.3 13.4 6.1 5.0 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SRP1_TIP1 PF00660.12 CCH63174.1 - 5.5e-27 93.6 0.1 8e-27 93.0 0.1 1.2 1 0 0 1 1 1 1 Seripauperin and TIP1 family SRP1_TIP1 PF00660.12 CCH63175.1 - 1.3e-23 82.8 2.7 1.3e-23 82.8 1.9 3.0 2 1 1 3 3 3 1 Seripauperin and TIP1 family BBP1_C PF15272.1 CCH63175.1 - 0.87 9.1 4.1 2.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal EF-hand_4 PF12763.2 CCH63176.1 - 2e-23 82.1 0.5 2.1e-12 46.6 0.0 3.2 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCH63176.1 - 9.3e-10 38.5 0.0 5.3e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCH63176.1 - 2.2e-08 32.7 0.0 0.0035 16.5 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF1720 PF08226.6 CCH63176.1 - 5.6e-06 26.3 48.5 0.00016 21.6 13.8 9.6 3 3 5 8 8 8 3 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 CCH63176.1 - 4.4e-05 23.0 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CCH63176.1 - 0.0025 17.3 0.0 1.7 8.3 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair Ribosomal_L29 PF00831.18 CCH63176.1 - 2.3 7.9 11.4 9.4 6.0 3.0 3.0 2 0 0 2 2 2 0 Ribosomal L29 protein RRM_1 PF00076.17 CCH63177.1 - 1.1e-18 66.6 0.5 2.2e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCH63177.1 - 4.5e-11 42.5 0.0 6.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCH63177.1 - 1.1e-09 38.0 0.1 6.6e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PIR PF00399.14 CCH63178.1 - 1.8e-06 27.0 2.2 1.8e-06 27.0 1.5 5.4 5 0 0 5 5 5 1 Yeast PIR protein repeat zf-FCS PF06467.9 CCH63178.1 - 0.49 10.0 13.0 10 5.8 0.0 4.7 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DZR PF12773.2 CCH63178.1 - 5.7 6.8 15.7 51 3.8 0.1 3.5 2 1 0 2 2 2 0 Double zinc ribbon SRP1_TIP1 PF00660.12 CCH63179.1 - 6.3e-27 93.4 0.1 1.2e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family DNA_pol_viral_N PF00242.12 CCH63179.1 - 0.49 9.3 5.7 0.55 9.1 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CCH63179.1 - 0.53 8.5 8.7 0.56 8.4 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Mucin PF01456.12 CCH63179.1 - 2.1 8.1 20.0 3.7 7.3 13.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DDHD PF02862.12 CCH63179.1 - 3.1 7.5 8.1 4.9 6.8 5.6 1.3 1 0 0 1 1 1 0 DDHD domain RAP1 PF07218.6 CCH63179.1 - 7.2 4.5 11.2 9.4 4.1 7.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SRP1_TIP1 PF00660.12 CCH63180.1 - 3.8e-18 65.2 0.8 3.8e-18 65.2 0.6 2.8 3 0 0 3 3 3 1 Seripauperin and TIP1 family EF-hand_4 PF12763.2 CCH63181.1 - 5.2e-29 100.0 0.0 8.6e-14 51.1 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCH63181.1 - 4.3e-10 39.5 0.0 0.00018 21.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCH63181.1 - 2.4e-08 32.6 0.0 0.0042 16.3 0.0 4.1 4 0 0 4 4 4 2 EF hand DUF1720 PF08226.6 CCH63181.1 - 1.7e-06 27.9 52.8 1.4e-05 25.0 17.4 11.0 4 2 4 8 8 8 5 Domain of unknown function (DUF1720) EF-hand_8 PF13833.1 CCH63181.1 - 2.2e-05 23.9 0.0 0.21 11.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCH63181.1 - 7.8e-05 22.2 0.0 0.68 9.9 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain Cwf_Cwc_15 PF04889.7 CCH63181.1 - 0.0036 17.0 17.5 0.0036 17.0 12.1 4.1 5 0 0 5 5 5 1 Cwf15/Cwc15 cell cycle control protein E3_binding PF02817.12 CCH63181.1 - 0.027 14.1 0.1 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain SRP1_TIP1 PF00660.12 CCH63182.1 - 2.4e-25 88.3 0.5 5.4e-25 87.2 0.3 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 CCH63182.1 - 2.5e-06 26.6 6.9 2.5e-06 26.6 4.8 3.0 2 0 0 2 2 2 1 Yeast PIR protein repeat Macoilin PF09726.4 CCH63182.1 - 0.12 10.6 16.2 0.13 10.5 11.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2201_N PF13203.1 CCH63182.1 - 0.35 10.0 13.4 0.6 9.2 9.1 1.6 1 1 0 1 1 1 0 Putative metallopeptidase domain CDC27 PF09507.5 CCH63182.1 - 0.38 9.9 24.5 0.47 9.6 17.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.4 CCH63182.1 - 1.1 7.8 17.7 1.5 7.4 12.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DNA_pol_viral_N PF00242.12 CCH63182.1 - 1.7 7.6 12.3 2 7.3 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Presenilin PF01080.12 CCH63182.1 - 2.3 6.9 15.2 3.2 6.4 10.5 1.1 1 0 0 1 1 1 0 Presenilin SOBP PF15279.1 CCH63182.1 - 3.1 8.0 14.0 3.9 7.7 9.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF572 PF04502.8 CCH63182.1 - 3.6 6.6 18.5 4.3 6.4 12.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 CCH63182.1 - 5.3 6.8 9.5 7.3 6.3 6.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CCH63182.1 - 5.4 4.5 13.0 6 4.4 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.14 CCH63182.1 - 5.7 5.5 10.5 7.8 5.0 7.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TATR PF03430.8 CCH63182.1 - 7.2 5.1 10.3 8.3 4.9 7.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Pneumo_att_G PF05539.6 CCH63182.1 - 7.2 5.8 23.1 8.8 5.5 16.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF2413 PF10310.4 CCH63182.1 - 8.6 5.0 22.8 12 4.5 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DnaJ-X PF14308.1 CCH63183.1 - 2.3e-58 196.8 6.3 2.3e-58 196.8 4.4 2.6 2 1 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.26 CCH63183.1 - 3.9e-27 93.7 1.2 1.2e-26 92.1 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain Rb_C PF08934.5 CCH63183.1 - 0.2 11.2 0.1 0.2 11.2 0.1 2.6 3 0 0 3 3 3 0 Rb C-terminal domain DUF3210 PF11489.3 CCH63184.1 - 2.3e-22 79.5 50.6 2.3e-22 79.5 35.1 4.4 2 1 2 4 4 4 1 Protein of unknown function (DUF3210) Sec3-PIP2_bind PF15277.1 CCH63185.1 - 5.9e-20 70.9 1.4 5.9e-20 70.9 1.0 2.7 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 CCH63186.1 - 2.5e-130 435.7 29.2 2.5e-130 435.7 20.2 3.2 3 1 0 3 3 3 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CCH63186.1 - 1e-23 83.0 1.3 2.1e-23 81.9 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Helicase_C PF00271.26 CCH63187.1 - 2.4e-20 72.1 0.1 7.4e-20 70.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCH63187.1 - 2.2e-18 66.3 0.1 1.6e-17 63.5 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 CCH63187.1 - 1.1e-17 64.5 0.0 1.1e-17 64.5 0.0 3.5 3 1 2 5 5 5 1 Type III restriction enzyme, res subunit Sigma70_r1_2 PF00140.15 CCH63187.1 - 0.032 13.8 1.2 0.07 12.8 0.8 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 bZIP_1 PF00170.16 CCH63188.1 - 0.0012 18.7 19.5 0.0019 18.0 11.3 2.9 2 1 0 2 2 2 1 bZIP transcription factor DUF4407 PF14362.1 CCH63188.1 - 1.4 7.8 6.8 2.4 7.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LETM1 PF07766.8 CCH63189.1 - 9e-66 221.6 10.8 1.5e-65 220.9 7.5 1.3 1 0 0 1 1 1 1 LETM1-like protein Dimerisation PF08100.6 CCH63190.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Dimerisation domain Rpr2 PF04032.11 CCH63191.1 - 6.6e-19 67.5 2.5 8.2e-19 67.2 1.8 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Proteasome PF00227.21 CCH63192.1 - 5.8e-56 188.7 0.0 7.6e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCH63192.1 - 1.4e-13 49.8 0.1 1.4e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YqzE PF14038.1 CCH63192.1 - 0.013 15.2 2.5 0.028 14.1 1.7 1.6 1 0 0 1 1 1 0 YqzE-like protein APC_CDC26 PF10471.4 CCH63192.1 - 0.052 14.2 6.2 0.12 13.1 4.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Snapin_Pallidin PF14712.1 CCH63193.1 - 8e-08 32.4 4.7 1e-07 32.1 3.2 1.1 1 0 0 1 1 1 1 Snapin/Pallidin Allexi_40kDa PF05549.6 CCH63193.1 - 0.012 14.9 1.4 0.013 14.8 0.9 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein GreA_GreB_N PF03449.10 CCH63193.1 - 0.039 13.9 0.6 0.073 13.1 0.4 1.7 1 1 0 1 1 1 0 Transcription elongation factor, N-terminal DUF2206 PF09971.4 CCH63193.1 - 0.084 11.6 0.5 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Fib_alpha PF08702.5 CCH63193.1 - 0.31 11.1 6.0 0.43 10.6 4.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 CCH63193.1 - 0.39 10.5 5.4 1.7 8.4 3.8 1.9 1 1 0 1 1 1 0 Prefoldin subunit Nup54 PF13874.1 CCH63193.1 - 0.41 10.3 4.0 0.54 9.9 2.5 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 CCH63193.1 - 0.68 10.2 4.7 5.7 7.2 2.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 CCH63193.1 - 1.3 8.7 5.3 2.5 7.7 0.5 2.1 1 1 1 2 2 2 0 Prefoldin subunit Syntaxin PF00804.20 CCH63193.1 - 1.5 9.0 6.8 2.7 8.2 4.7 1.5 1 1 0 1 1 1 0 Syntaxin OST3_OST6 PF04756.8 CCH63194.1 - 1.5e-16 60.3 10.9 1.5e-16 60.3 7.5 2.0 2 0 0 2 2 2 1 OST3 / OST6 family EF-hand_4 PF12763.2 CCH63195.1 - 2.4e-44 149.3 2.2 2.4e-44 149.3 1.5 2.4 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CCH63195.1 - 1.3e-19 70.5 8.9 7.7e-12 45.2 0.2 2.8 2 1 1 3 3 3 2 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 CCH63195.1 - 0.018 14.3 1.6 0.061 12.6 0.7 2.3 3 0 0 3 3 3 0 EF hand COG2 PF06148.6 CCH63195.1 - 0.033 14.0 2.6 0.63 9.9 0.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sugarporin_N PF11471.3 CCH63195.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension EF-hand_8 PF13833.1 CCH63195.1 - 0.049 13.2 2.4 0.18 11.4 0.7 2.4 2 0 0 2 2 2 0 EF-hand domain pair He_PIG PF05345.7 CCH63196.1 - 8.3e-12 44.9 4.9 5.4e-05 23.1 0.0 4.8 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.5 CCH63196.1 - 2.4e-10 39.5 0.1 2.4e-10 39.5 0.1 2.5 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CcoS PF03597.10 CCH63196.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Mito_carr PF00153.22 CCH63197.1 - 3.7e-62 206.0 1.8 4.4e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 CCH63197.1 - 2.3e-13 48.3 7.5 5.2e-05 22.2 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CCH63197.1 - 8.8e-13 48.1 9.3 6.9e-11 42.1 2.3 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CCH63197.1 - 1.7e-10 39.8 9.1 0.035 13.9 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CCH63197.1 - 4.3e-06 25.8 8.6 0.022 14.0 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CCH63197.1 - 0.0002 20.9 1.1 0.57 9.8 0.4 2.7 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CCH63197.1 - 0.00035 20.5 0.2 0.16 12.0 0.1 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CCH63197.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain DUF2177 PF09945.4 CCH63197.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) HORMA PF02301.13 CCH63198.1 - 1.2e-20 73.8 0.4 1.8e-20 73.3 0.3 1.3 1 0 0 1 1 1 1 HORMA domain DNA_mis_repair PF01119.14 CCH63199.1 - 1.6e-24 85.6 0.5 6e-24 83.7 0.1 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CCH63199.1 - 5.6e-24 84.3 0.1 3.1e-23 81.9 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 CCH63199.1 - 1.9e-12 47.0 0.3 1.9e-12 47.0 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCH63199.1 - 7.2e-10 38.5 2.1 9.1e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EOS1 PF12326.3 CCH63200.1 - 6.9e-62 207.4 12.8 6.9e-62 207.4 8.9 1.9 2 1 0 2 2 2 1 N-glycosylation protein DMP1 PF07263.6 CCH63200.1 - 0.051 12.2 3.1 0.092 11.4 2.1 1.3 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) Glutenin_hmw PF03157.8 CCH63201.1 - 0.00091 17.6 66.6 0.073 11.3 25.4 2.1 1 1 1 2 2 2 2 High molecular weight glutenin subunit