# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PIF1 PF05970.14 KNZ71251.1 - 4.2e-16 59.1 0.1 4.6e-16 59.0 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF4315 PF14193.6 KNZ71252.1 - 0.039 14.0 12.3 0.056 13.4 11.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) DUF572 PF04502.13 KNZ71252.1 - 2.4 7.7 8.8 0.19 11.3 2.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF1682 PF07946.14 KNZ71252.1 - 2.7 7.1 10.7 4.9 6.3 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ATP-grasp_2 PF08442.10 KNZ71253.1 - 8.2e-65 218.2 1.4 6e-64 215.3 0.3 2.1 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 KNZ71253.1 - 2.9e-26 92.1 0.2 5.6e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KNZ71253.1 - 1.1e-08 34.8 0.4 2.5e-08 33.7 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 KNZ71253.1 - 0.0014 18.4 0.1 0.015 15.1 0.1 2.3 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KNZ71253.1 - 0.0034 16.9 0.2 0.15 11.5 0.0 2.4 1 1 1 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PASTA PF03793.19 KNZ71253.1 - 0.033 14.0 0.3 4.4 7.2 0.1 2.9 2 0 0 2 2 2 0 PASTA domain Succ_CoA_lig PF13607.6 KNZ71253.1 - 0.04 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain ATP-grasp PF02222.22 KNZ71253.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.8 1 1 0 1 1 1 0 ATP-grasp domain SGT1 PF07093.11 KNZ71254.1 - 7.6e-85 285.5 14.0 2.7e-48 164.8 11.2 3.7 2 1 0 2 2 2 2 SGT1 protein YjcQ PF09639.10 KNZ71254.1 - 0.028 14.6 0.2 0.11 12.7 0.0 2.2 2 0 0 2 2 2 0 YjcQ protein XPA_C PF05181.12 KNZ71255.1 - 5.1e-25 87.2 3.0 1e-24 86.2 3.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus ANAPC_CDC26 PF10471.9 KNZ71255.1 - 0.0054 17.5 1.0 0.0054 17.5 1.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex APC subunit CDC26 XPA_N PF01286.18 KNZ71255.1 - 0.068 13.2 11.6 0.048 13.7 6.4 2.6 2 0 0 2 2 2 0 XPA protein N-terminal TipAS PF07739.13 KNZ71255.1 - 0.53 10.9 6.4 0.2 12.2 3.3 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Hist_deacetyl PF00850.19 KNZ71256.1 - 1.8e-84 283.8 0.0 2.4e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 KNZ71256.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 NIL domain MFS_1 PF07690.16 KNZ71257.1 - 2.3e-19 69.6 37.3 6.7e-18 64.7 5.3 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily Asparaginase_2 PF01112.18 KNZ71258.1 - 1e-72 244.8 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Asparaginase DGF-1_5 PF11038.8 KNZ71258.1 - 0.0082 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 G_glu_transpept PF01019.21 KNZ71258.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase STE3 PF02076.15 KNZ71259.1 - 3.6e-63 213.5 18.3 4.4e-63 213.2 18.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor YcaO PF02624.16 KNZ71259.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding EBP PF05241.12 KNZ71260.1 - 0.013 15.0 10.7 0.033 13.7 10.7 1.6 1 1 0 1 1 1 0 Emopamil binding protein PDDEXK_10 PF07788.11 KNZ71260.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Pex24p PF06398.11 KNZ71262.1 - 3e-24 85.7 5.1 1.1e-20 73.9 0.0 2.4 2 1 0 2 2 2 2 Integral peroxisomal membrane peroxin Kdo PF06293.14 KNZ71263.1 - 3.4e-06 26.5 0.1 4.9e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ71263.1 - 1.7e-05 24.5 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KNZ71263.1 - 6.8e-05 22.9 2.4 0.0067 16.4 1.7 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ71263.1 - 0.00074 19.0 0.1 0.0011 18.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KNZ71263.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KNZ71263.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase SH3_2 PF07653.17 KNZ71264.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Variant SH3 domain zf-CCHC PF00098.23 KNZ71265.1 - 3.5e-06 26.9 2.1 3.5e-06 26.9 2.1 2.0 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 KNZ71265.1 - 0.00082 19.6 0.0 0.0022 18.2 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF2457 PF10446.9 KNZ71265.1 - 0.42 9.7 9.8 0.58 9.2 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rrn6 PF10214.9 KNZ71265.1 - 2.7 6.4 6.5 3.6 6.0 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5427 PF10310.9 KNZ71267.1 - 2.6e-53 181.6 6.7 1.1e-49 169.7 0.1 2.4 1 1 1 2 2 2 2 Family of unknown function (DUF5427) Complex1_30kDa PF00329.19 KNZ71268.1 - 3.4e-45 153.6 0.0 4.8e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.11 KNZ71269.1 - 7e-67 225.1 5.7 7.9e-67 224.9 5.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Mesd PF10185.9 KNZ71269.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor LRR_RI_capping PF18779.1 KNZ71269.1 - 0.13 11.9 0.3 0.29 10.8 0.3 1.5 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat Nup54 PF13874.6 KNZ71269.1 - 0.29 11.2 8.5 3.3 7.8 3.2 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 APG6_N PF17675.1 KNZ71269.1 - 1.8 9.1 11.2 7.7 7.0 11.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region COesterase PF00135.28 KNZ71271.1 - 3.4e-81 273.7 0.1 8.4e-69 232.8 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ71271.1 - 6.4e-11 42.5 0.2 9.6e-10 38.7 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ71271.1 - 0.0011 19.6 0.3 0.0031 18.1 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KNZ71271.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MARVEL PF01284.23 KNZ71274.1 - 0.3 11.1 12.3 0.86 9.6 11.7 2.0 1 1 0 1 1 1 0 Membrane-associating domain MFS_1 PF07690.16 KNZ71275.1 - 1.9e-14 53.3 17.1 2.6e-14 52.9 17.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ71275.1 - 0.026 13.4 12.6 0.049 12.5 6.6 2.8 1 1 1 2 2 2 0 Sugar (and other) transporter DUF2516 PF10724.9 KNZ71275.1 - 1.6 9.1 5.3 1.6 9.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) Trp_halogenase PF04820.14 KNZ71276.1 - 4.6e-24 85.1 0.0 9.8e-18 64.2 0.0 2.1 1 1 1 2 2 2 2 Tryptophan halogenase ketoacyl-synt PF00109.26 KNZ71278.1 - 8.1e-07 28.9 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PE_PPE_C PF12484.8 KNZ71279.1 - 0.03 15.2 3.9 0.081 13.8 3.9 1.7 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal Coa1 PF08695.10 KNZ71280.1 - 5.4e-33 113.2 0.1 8e-33 112.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Abhydrolase_1 PF00561.20 KNZ71281.1 - 2.5e-16 60.1 0.2 1.9e-13 50.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ71281.1 - 5.2e-12 46.8 0.0 6.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ71281.1 - 6.6e-09 35.4 0.0 3.1e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KNZ71281.1 - 8.3e-06 26.1 0.0 9.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KNZ71281.1 - 0.0042 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3328 PF11807.8 KNZ71282.1 - 5.4e-13 49.2 0.0 5.6e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) zf-CCHC PF00098.23 KNZ71285.1 - 0.36 11.0 3.9 0.79 9.9 3.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C2 PF00648.21 KNZ71286.1 - 1.2e-67 228.1 0.1 6.7e-67 225.6 0.1 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease PEP_mutase PF13714.6 KNZ71287.1 - 2.1e-40 138.7 1.9 3.2e-40 138.1 1.9 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KNZ71287.1 - 3.7e-19 68.6 0.8 4.9e-19 68.2 0.8 1.1 1 0 0 1 1 1 1 Isocitrate lyase family GMC_oxred_N PF00732.19 KNZ71288.1 - 6.2e-50 170.2 0.0 8e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ71288.1 - 1.4e-36 126.1 0.0 2.3e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KNZ71288.1 - 0.00079 19.1 0.8 0.0043 16.7 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ71288.1 - 0.001 19.3 0.1 0.0031 17.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ71288.1 - 0.0039 16.3 0.0 0.0058 15.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ71288.1 - 0.042 12.9 0.3 0.42 9.6 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 KNZ71288.1 - 0.046 12.9 0.0 0.19 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ71288.1 - 0.062 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NB-ARC PF00931.22 KNZ71290.1 - 0.022 13.9 0.0 0.027 13.7 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain HNH_2 PF13391.6 KNZ71292.1 - 0.043 13.9 0.0 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 HNH endonuclease HsbA PF12296.8 KNZ71293.1 - 9.7e-10 38.9 4.9 1.9e-09 38.0 4.9 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A LAGLIDADG_1 PF00961.19 KNZ71294.1 - 2.3e-31 108.8 0.0 2.8e-19 70.0 0.1 2.4 2 0 0 2 2 2 2 LAGLIDADG endonuclease COX1 PF00115.20 KNZ71294.1 - 8.6e-16 57.8 1.3 1.3e-15 57.3 1.3 1.3 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I LAGLIDADG_3 PF14528.6 KNZ71294.1 - 4.7e-05 23.6 0.0 0.17 12.2 0.0 2.9 2 1 0 2 2 2 2 LAGLIDADG-like domain Endonuc_subdom PF09062.10 KNZ71294.1 - 0.0011 19.7 0.0 0.049 14.4 0.0 2.7 2 0 0 2 2 2 1 PI-PfuI Endonuclease subdomain Hom_end PF05204.14 KNZ71294.1 - 0.14 12.4 0.0 24 5.1 0.0 2.7 2 1 0 2 2 2 0 Homing endonuclease ATP-synt_C PF00137.21 KNZ71295.1 - 4.4e-12 46.2 14.2 5.8e-12 45.8 14.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit C COX1 PF00115.20 KNZ71296.1 - 2e-17 63.2 3.2 2.8e-17 62.7 3.2 1.2 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I NUMOD3 PF07460.11 KNZ71296.1 - 4.2e-06 26.9 0.1 0.022 15.0 0.0 3.0 3 0 0 3 3 3 2 NUMOD3 motif (2 copies) NUMOD1 PF07453.13 KNZ71296.1 - 0.059 13.6 0.5 0.32 11.3 0.2 2.5 2 1 0 2 2 2 0 NUMOD1 domain GIY-YIG PF01541.24 KNZ71296.1 - 0.065 13.5 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 GIY-YIG catalytic domain Tropomyosin_1 PF12718.7 KNZ71297.1 - 5.4e-17 62.3 21.8 4.2e-12 46.4 13.3 2.1 2 0 0 2 2 2 2 Tropomyosin like Rb_C PF08934.10 KNZ71297.1 - 0.0054 16.6 1.3 0.55 10.0 0.2 2.5 1 1 1 2 2 2 2 Rb C-terminal domain ROF PF07073.12 KNZ71297.1 - 0.033 14.3 4.6 0.86 9.8 0.5 2.6 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) SPATA24 PF15175.6 KNZ71297.1 - 0.036 14.0 14.0 0.067 13.1 0.8 2.9 1 1 2 3 3 3 0 Spermatogenesis-associated protein 24 Phage_lysozyme2 PF18013.1 KNZ71297.1 - 0.11 12.5 1.4 0.22 11.5 1.4 1.7 1 1 0 1 1 1 0 Phage tail lysozyme CCDC-167 PF15188.6 KNZ71297.1 - 0.28 11.6 8.5 0.24 11.8 3.8 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mst1_SARAH PF11629.8 KNZ71297.1 - 0.42 10.7 5.2 2.8 8.1 0.2 3.2 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Csm1_N PF18504.1 KNZ71297.1 - 0.43 10.9 19.3 0.12 12.7 2.3 3.5 3 1 0 3 3 3 0 Csm1 N-terminal domain Swi5 PF07061.11 KNZ71297.1 - 0.82 9.8 11.2 0.94 9.6 3.1 3.3 2 1 1 3 3 3 0 Swi5 Fez1 PF06818.15 KNZ71297.1 - 1.6 9.2 17.7 6.4 7.2 17.7 1.8 1 1 0 1 1 1 0 Fez1 CHD5 PF04420.14 KNZ71297.1 - 4.7 7.0 9.4 7.1 6.5 1.0 3.3 1 1 1 3 3 3 0 CHD5-like protein Ribosomal_L37e PF01907.19 KNZ71300.1 - 1.8e-25 88.9 12.1 3.1e-25 88.1 12.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KNZ71300.1 - 0.0056 16.7 1.9 0.0089 16.0 1.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 KNZ71300.1 - 0.012 15.7 1.2 0.014 15.5 1.0 1.4 1 1 0 1 1 1 0 SelR domain HypA PF01155.19 KNZ71300.1 - 0.034 14.2 1.0 0.051 13.6 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zn-ribbon_14 PF16503.5 KNZ71300.1 - 0.52 9.9 4.8 0.86 9.2 0.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon zf-C3HC4_2 PF13923.6 KNZ71300.1 - 0.75 9.7 5.7 7.9 6.4 6.8 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 KNZ71300.1 - 0.87 9.4 5.3 15 5.4 5.8 2.1 1 1 1 2 2 2 0 zinc-ribbon domain Aminotran_3 PF00202.21 KNZ71301.1 - 1.9e-10 40.0 0.0 2.2e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short_C2 PF13561.6 KNZ71302.1 - 5.5e-47 160.3 0.0 6.9e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ71302.1 - 5.3e-36 123.9 0.1 6.2e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ71302.1 - 1.5e-09 38.1 0.0 2.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 KNZ71302.1 - 0.01 15.3 0.1 0.024 14.1 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein LAGLIDADG_2 PF03161.13 KNZ71303.1 - 8.6e-33 113.7 1.2 2.8e-32 112.1 1.2 1.8 1 1 0 1 1 1 1 LAGLIDADG DNA endonuclease family Alpha_kinase PF02816.18 KNZ71303.1 - 0.042 14.0 0.2 0.063 13.4 0.2 1.4 1 0 0 1 1 1 0 Alpha-kinase family DUF1638 PF07796.11 KNZ71303.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) DUF4883 PF16224.5 KNZ71303.1 - 0.21 11.8 3.9 0.94 9.7 1.1 2.3 2 0 0 2 2 2 0 DOmain of unknown function (DUF4883) Cytochrom_B_C PF00032.17 KNZ71304.1 - 1.3e-15 57.5 1.2 1.8e-15 57.1 1.2 1.2 1 0 0 1 1 1 1 Cytochrome b(C-terminal)/b6/petD LAGLIDADG_2 PF03161.13 KNZ71305.1 - 2.6e-39 135.0 1.9 3.3e-39 134.6 1.9 1.1 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family ABC2_membrane PF01061.24 KNZ71307.1 - 5.9e-27 94.5 16.4 5.9e-27 94.5 16.4 1.9 2 1 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 KNZ71307.1 - 1.2e-06 28.3 0.6 3.1e-06 27.0 0.6 1.6 1 0 0 1 1 1 1 CDR ABC transporter TPP_enzyme_M PF00205.22 KNZ71308.1 - 3.8e-16 59.1 0.0 6.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNZ71308.1 - 1.3e-11 44.6 0.0 4.6e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KNZ71308.1 - 2.5e-06 27.2 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain p450 PF00067.22 KNZ71312.1 - 2.1e-43 148.8 0.0 2.5e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.20 KNZ71313.1 - 2.2e-51 175.0 0.6 2.8e-51 174.7 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KNZ71313.1 - 0.00072 19.9 0.0 0.08 13.3 0.0 2.8 1 1 2 3 3 3 2 HEAT repeats Arm PF00514.23 KNZ71313.1 - 0.7 10.0 2.2 24 5.1 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Fungal_trans PF04082.18 KNZ71314.1 - 0.00027 20.1 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain gag-asp_proteas PF13975.6 KNZ71315.1 - 4.2e-07 30.4 0.0 7.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ71315.1 - 5.7e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ71315.1 - 0.012 15.4 0.1 0.022 14.5 0.1 1.5 1 1 0 1 1 1 0 Aspartyl protease TipE PF16972.5 KNZ71316.1 - 0.07 12.3 2.5 0.12 11.5 2.5 1.4 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE DUF3716 PF12511.8 KNZ71316.1 - 0.14 12.2 0.3 0.14 12.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) Glyco_hydro_43 PF04616.14 KNZ71319.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Pkinase_fungal PF17667.1 KNZ71320.1 - 6e-38 130.7 0.0 7.4e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Glyco_hydro_61 PF03443.14 KNZ71321.1 - 1.2e-09 38.4 0.0 1.3e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 gag-asp_proteas PF13975.6 KNZ71322.1 - 7.5e-07 29.6 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ71322.1 - 2.8e-06 27.9 0.0 7.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ71322.1 - 0.025 14.4 0.1 0.045 13.5 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 KNZ71324.1 - 0.00077 18.9 0.0 0.00077 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71324.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Cytochrome_B PF00033.19 KNZ71325.1 - 2.5e-64 216.6 14.6 2.5e-64 216.6 14.6 1.3 2 0 0 2 2 2 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 KNZ71325.1 - 4.2e-41 140.7 13.1 5.1e-41 140.5 13.1 1.1 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 KNZ71325.1 - 0.14 12.5 0.9 0.14 12.5 0.9 3.8 2 1 1 3 3 3 0 Cytochrome b(C-terminal)/b6/petD FtsX PF02687.21 KNZ71325.1 - 1.6 9.3 13.0 72 3.9 11.8 2.4 1 1 1 2 2 2 0 FtsX-like permease family Ni_hydr_CYTB PF01292.20 KNZ71325.1 - 8.9 5.9 23.2 0.15 11.6 8.9 2.6 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 PIF1 PF05970.14 KNZ71326.1 - 4.5e-23 82.0 0.1 5.1e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PAE PF03283.13 KNZ71326.1 - 0.038 13.1 0.1 0.038 13.1 0.1 1.1 1 0 0 1 1 1 0 Pectinacetylesterase p450 PF00067.22 KNZ71327.1 - 2.7e-22 79.2 0.0 3.1e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_q2 PF00420.24 KNZ71331.1 - 4.8e-16 58.3 12.6 5.4e-16 58.1 12.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF3098 PF11297.8 KNZ71331.1 - 0.96 9.1 9.7 0.4 10.3 7.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3098) ORC6 PF05460.13 KNZ71332.1 - 0.92 8.7 6.4 1.2 8.3 6.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ketoacyl-synt PF00109.26 KNZ71333.1 - 1.4e-33 116.6 1.6 1.6e-32 113.1 0.7 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KNZ71333.1 - 2.5e-31 108.1 0.4 3.5e-31 107.7 0.4 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KNZ71333.1 - 2.7e-05 23.7 0.2 0.00062 19.2 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Copper-fist PF00649.18 KNZ71334.1 - 1.1 8.8 11.9 6.8 6.3 0.5 3.0 1 1 1 2 2 2 0 Copper fist DNA binding domain PolC_DP2 PF03833.13 KNZ71334.1 - 3.5 5.4 6.5 3.8 5.3 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cript PF10235.9 KNZ71334.1 - 6.8 7.3 12.0 0.75 10.4 4.5 2.4 1 1 1 2 2 2 0 Microtubule-associated protein CRIPT GDA1_CD39 PF01150.17 KNZ71335.1 - 3.2e-32 111.7 0.0 1.2e-31 109.9 0.0 1.7 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KNZ71335.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RVP_2 PF08284.11 KNZ71336.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Phasin PF05597.11 KNZ71337.1 - 0.025 14.6 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BAR_2 PF10455.9 KNZ71338.1 - 2.1e-10 40.3 1.0 2.6e-10 39.9 1.0 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KNZ71338.1 - 0.0088 15.7 0.3 0.011 15.4 0.3 1.1 1 0 0 1 1 1 1 BAR domain DUF3328 PF11807.8 KNZ71339.1 - 2.8e-15 56.7 1.2 7.8e-15 55.2 1.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PIF1 PF05970.14 KNZ71340.1 - 3.4e-28 98.9 0.0 3.7e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase COX2_TM PF02790.15 KNZ71341.1 - 2.4e-31 107.7 1.7 2.7e-31 107.6 1.7 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain E1-E2_ATPase PF00122.20 KNZ71341.1 - 0.24 10.9 1.3 0.28 10.7 1.3 1.0 1 0 0 1 1 1 0 E1-E2 ATPase Saf_2TM PF18303.1 KNZ71341.1 - 0.36 10.4 2.4 2.5 7.7 0.3 1.9 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain COX2 PF00116.20 KNZ71342.1 - 4.1e-29 100.9 0.1 4.6e-29 100.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Herpes_Helicase PF02689.14 KNZ71344.1 - 0.00026 19.1 0.0 0.00027 19.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ71344.1 - 0.03 14.1 0.1 0.062 13.1 0.1 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ71345.1 - 7.5e-22 78.0 0.0 9.1e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ71345.1 - 0.012 15.6 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ71345.1 - 0.21 11.3 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF5487 PF17589.2 KNZ71346.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5487) Kdo PF06293.14 KNZ71348.1 - 8.6e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNZ71348.1 - 2.6e-05 23.7 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KNZ71348.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ71348.1 - 0.0022 17.9 0.7 0.003 17.5 0.7 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ71348.1 - 0.069 12.5 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KNZ71348.1 - 0.14 11.7 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KNZ71348.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Chromo PF00385.24 KNZ71349.1 - 8.3e-16 57.6 0.1 1.1e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SelB-wing_2 PF09106.11 KNZ71349.1 - 0.023 14.9 0.1 2.1 8.6 0.2 2.3 2 0 0 2 2 2 0 Elongation factor SelB, winged helix SF3a60_bindingd PF12108.8 KNZ71349.1 - 0.025 14.5 0.8 0.044 13.7 0.1 1.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Mtf2_C PF14061.6 KNZ71349.1 - 0.097 12.9 0.8 0.14 12.3 0.8 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 ATP-synt_A PF00119.20 KNZ71350.1 - 9.2e-22 78.0 13.1 1e-21 77.9 13.1 1.0 1 0 0 1 1 1 1 ATP synthase A chain DUF1290 PF06947.12 KNZ71350.1 - 0.11 12.7 8.4 2.1 8.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1290) DUF2070 PF09843.9 KNZ71350.1 - 2.6 6.3 11.9 2.8 6.1 11.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Chromo PF00385.24 KNZ71351.1 - 4.7e-15 55.2 0.1 5.9e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ71351.1 - 0.048 13.8 0.1 0.066 13.4 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 COX3 PF00510.18 KNZ71354.1 - 8.5e-24 84.8 11.8 9.3e-24 84.7 11.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III NTP_transferase PF00483.23 KNZ71355.1 - 2.2e-31 109.3 0.0 8.3e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase MannoseP_isomer PF01050.18 KNZ71355.1 - 0.00021 21.2 0.1 0.00036 20.4 0.1 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase DUF364 PF04016.12 KNZ71355.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation DivIC PF04977.15 KNZ71355.1 - 0.92 9.3 3.3 0.36 10.6 0.7 1.7 2 0 0 2 2 2 0 Septum formation initiator PAXX PF15384.6 KNZ71356.1 - 0.021 14.6 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 G-alpha PF00503.20 KNZ71357.1 - 3.6e-98 329.0 0.0 4.8e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ71357.1 - 3.8e-08 33.0 1.0 0.031 13.8 0.5 3.4 2 1 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KNZ71357.1 - 0.0022 17.5 0.1 0.0034 16.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_22 PF13401.6 KNZ71357.1 - 0.024 14.9 0.0 0.062 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KNZ71357.1 - 0.038 14.2 0.1 3.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KNZ71357.1 - 0.067 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KNZ71357.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1643 PF07799.12 KNZ71358.1 - 0.18 12.0 1.9 0.23 11.6 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1643) HisKA_3 PF07730.13 KNZ71358.1 - 4.6 7.8 5.6 3.7 8.1 0.1 3.1 2 1 2 4 4 4 0 Histidine kinase DUF883 PF05957.13 KNZ71358.1 - 6.7 7.4 16.5 87 3.8 0.5 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) AAA_18 PF13238.6 KNZ71359.1 - 1e-07 32.6 2.2 1.2e-06 29.1 2.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNZ71359.1 - 5e-05 23.5 0.0 0.00011 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KNZ71359.1 - 0.00062 20.2 0.5 0.021 15.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KNZ71359.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.18 KNZ71359.1 - 0.043 13.5 0.1 0.29 10.8 0.1 2.0 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 KNZ71359.1 - 0.12 11.8 0.1 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 KNZ71359.1 - 0.13 12.5 1.0 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KNZ71359.1 - 0.19 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FAD_binding_2 PF00890.24 KNZ71360.1 - 5.4e-75 253.0 1.5 1.8e-65 221.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Cyt-b5 PF00173.28 KNZ71360.1 - 2.3e-23 82.1 0.0 7.6e-23 80.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 KNZ71360.1 - 1.9e-10 40.5 0.1 2.5e-07 30.2 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ71360.1 - 2.4e-09 37.2 0.6 3.9e-05 23.4 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 KNZ71360.1 - 6.5e-07 28.8 0.2 9.6e-05 21.6 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KNZ71360.1 - 9.4e-07 29.0 2.1 2.6e-06 27.6 0.0 2.9 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KNZ71360.1 - 5.3e-06 25.9 0.2 1e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KNZ71360.1 - 7.8e-05 21.6 4.4 0.00022 20.0 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 KNZ71360.1 - 8.4e-05 22.0 0.1 0.097 11.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ71360.1 - 0.00021 20.6 0.7 0.19 11.0 0.2 2.4 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 KNZ71360.1 - 0.00022 20.6 0.1 0.0004 19.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 KNZ71360.1 - 0.00043 19.7 1.9 0.00061 19.3 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KNZ71360.1 - 0.0022 17.1 0.8 0.0083 15.2 0.3 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KNZ71360.1 - 0.0022 17.4 1.7 0.35 10.1 0.5 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KNZ71360.1 - 0.0022 18.5 0.3 0.07 13.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ71360.1 - 0.0053 16.8 0.2 4.7 7.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KNZ71360.1 - 0.028 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_M19 PF01244.21 KNZ71361.1 - 1.3e-101 340.0 0.0 1.6e-101 339.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) G-patch_2 PF12656.7 KNZ71362.1 - 4.8e-22 77.8 0.2 2e-21 75.8 0.2 2.2 1 0 0 1 1 1 1 G-patch domain EIF4E-T PF10477.9 KNZ71362.1 - 0.033 13.0 17.7 0.032 13.1 17.7 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E G-patch PF01585.23 KNZ71362.1 - 0.063 13.2 1.0 0.24 11.3 1.0 2.1 1 1 0 1 1 1 0 G-patch domain Pantoate_transf PF02548.15 KNZ71363.1 - 1.3e-67 227.9 0.2 9.3e-46 156.3 0.0 3.1 2 1 1 3 3 3 3 Ketopantoate hydroxymethyltransferase Ras PF00071.22 KNZ71363.1 - 4e-35 120.8 0.0 6.7e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ71363.1 - 3.8e-14 52.9 0.0 8e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Chs7 PF12271.8 KNZ71364.1 - 3.9e-20 72.4 0.7 4.4e-20 72.2 0.7 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone SKG6 PF08693.10 KNZ71366.1 - 3.8 7.0 7.5 6.3 6.3 7.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DotD PF16816.5 KNZ71368.1 - 0.081 12.9 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 DotD protein Atg14 PF10186.9 KNZ71369.1 - 1.2e-48 165.8 0.0 2.1e-48 165.1 0.0 1.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3053 PF11254.8 KNZ71369.1 - 0.013 15.1 0.4 0.03 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) EzrA PF06160.12 KNZ71369.1 - 0.056 11.6 0.5 0.076 11.2 0.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-B_box PF00643.24 KNZ71369.1 - 0.34 11.1 4.2 0.66 10.2 4.2 1.5 1 0 0 1 1 1 0 B-box zinc finger FUSC PF04632.12 KNZ71369.1 - 4.8 5.6 6.9 7.1 5.0 6.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aldedh PF00171.22 KNZ71370.1 - 1.2e-168 561.4 0.0 1.4e-168 561.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase_Tyr PF07714.17 KNZ71371.1 - 2.2e-13 50.1 0.2 1.8e-06 27.4 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KNZ71371.1 - 1e-12 48.0 0.0 3.1e-08 33.3 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KNZ71371.1 - 0.061 12.7 0.1 0.096 12.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M36 PF02128.15 KNZ71373.1 - 5.5e-131 437.1 0.9 6.9e-131 436.8 0.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KNZ71373.1 - 0.00052 19.8 0.1 0.0019 18.0 0.1 2.0 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KNZ71373.1 - 0.0053 16.6 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain DUF5503 PF17607.2 KNZ71374.1 - 0.094 13.0 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5503) Chromo PF00385.24 KNZ71376.1 - 5e-09 35.9 0.3 7.7e-09 35.3 0.3 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tannase PF07519.11 KNZ71379.1 - 2.8e-76 257.3 0.0 3.4e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase PIF1 PF05970.14 KNZ71381.1 - 6.5e-34 117.7 0.1 8e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KNZ71381.1 - 0.00015 19.9 0.0 0.00019 19.5 0.0 1.1 1 0 0 1 1 1 1 Helicase 4HPAD_g_N PF18671.1 KNZ71381.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UPF0160 PF03690.13 KNZ71382.1 - 2.3e-129 431.6 0.0 2.9e-129 431.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) SAD_SRA PF02182.17 KNZ71384.1 - 1.1e-35 122.6 0.1 4.7e-33 114.1 0.1 2.1 1 1 0 1 1 1 1 SAD/SRA domain XhlA PF10779.9 KNZ71385.1 - 0.0044 17.2 0.7 0.0044 17.2 0.7 4.3 4 1 1 5 5 5 1 Haemolysin XhlA Snapin_Pallidin PF14712.6 KNZ71385.1 - 7.9 7.0 12.0 3.6 8.1 1.7 2.9 3 0 0 3 3 3 0 Snapin/Pallidin Mpp10 PF04006.12 KNZ71386.1 - 1.2e-108 364.3 39.0 1.8e-108 363.7 39.0 1.1 1 0 0 1 1 1 1 Mpp10 protein Fig1 PF12351.8 KNZ71387.1 - 1.9 8.4 17.1 0.7 9.8 8.5 2.8 1 1 1 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Lyase_8 PF02278.18 KNZ71388.1 - 1.2e-57 195.3 3.0 2e-57 194.6 3.0 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KNZ71388.1 - 1.5e-13 50.4 2.6 1.3e-09 37.4 0.9 2.3 2 1 0 2 2 2 2 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KNZ71388.1 - 1.4e-08 35.0 0.8 1.4e-08 35.0 0.8 2.8 3 0 0 3 3 3 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Lyase_8 PF02278.18 KNZ71390.1 - 7.1e-73 245.3 5.7 1.1e-72 244.7 5.7 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KNZ71390.1 - 1.4e-11 43.9 0.0 4e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KNZ71390.1 - 2.2e-10 40.8 0.0 5.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Thiolase_N PF00108.23 KNZ71391.1 - 4.3e-67 226.2 0.0 6.5e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNZ71391.1 - 8.5e-36 122.3 0.1 2e-35 121.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Ribosomal_S3_C PF00189.20 KNZ71391.1 - 2.7e-24 85.5 0.1 7.8e-24 84.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KNZ71391.1 - 2.5e-11 43.2 0.0 5.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 KH domain ketoacyl-synt PF00109.26 KNZ71391.1 - 0.0026 17.4 2.3 0.0044 16.6 0.6 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KNZ71391.1 - 0.023 14.5 1.1 0.82 9.6 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ldh_1_C PF02866.18 KNZ71391.1 - 0.078 12.9 0.0 2.7 7.9 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain UN_NPL4 PF11543.8 KNZ71391.1 - 0.18 12.3 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ribosomal_L32p PF01783.23 KNZ71392.1 - 2.2e-10 40.6 1.1 2.6e-10 40.4 1.1 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 KNZ71392.1 - 0.0031 17.4 1.7 0.0056 16.6 1.7 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 ADD_ATRX PF17981.1 KNZ71392.1 - 0.0055 16.5 2.4 0.09 12.7 0.1 2.1 1 1 1 2 2 2 2 Cysteine Rich ADD domain Zn-ribbon_8 PF09723.10 KNZ71392.1 - 0.11 12.7 1.9 0.28 11.3 0.2 2.0 1 1 1 2 2 2 0 Zinc ribbon domain ETC_C1_NDUFA5 PF04716.14 KNZ71393.1 - 8.2e-26 89.6 0.4 1.3e-25 88.9 0.1 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region LSM PF01423.22 KNZ71394.1 - 2.3e-18 65.7 0.1 3.3e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KNZ71394.1 - 0.0096 15.6 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Hfq protein PHD PF00628.29 KNZ71395.1 - 8.4e-11 41.6 7.9 8.4e-11 41.6 7.9 2.5 2 0 0 2 2 2 1 PHD-finger HABP4_PAI-RBP1 PF04774.15 KNZ71396.1 - 1.4e-11 45.3 9.8 1.4e-11 45.3 9.8 2.0 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family His_Phos_1 PF00300.22 KNZ71397.1 - 1.9e-25 89.7 0.0 2.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Memo PF01875.17 KNZ71398.1 - 3.6e-68 229.6 0.0 1.1e-67 228.1 0.0 1.7 1 1 0 1 1 1 1 Memo-like protein Ribosomal_L32e PF01655.18 KNZ71398.1 - 1.2e-49 167.2 1.7 1.9e-49 166.6 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 WD40 PF00400.32 KNZ71399.1 - 5.8e-07 30.1 0.6 1.1e-05 26.0 0.0 2.3 2 1 0 2 2 2 1 WD domain, G-beta repeat Pkinase PF00069.25 KNZ71400.1 - 2e-39 135.6 0.0 4.3e-38 131.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71400.1 - 6.6e-17 61.6 0.0 5.6e-16 58.6 0.0 2.4 2 2 1 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ71400.1 - 0.00029 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ71400.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ71400.1 - 0.0068 15.8 0.0 0.0098 15.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GTP_EFTU PF00009.27 KNZ71401.1 - 6.9e-54 182.4 0.1 1.1e-53 181.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KNZ71401.1 - 1.5e-42 144.4 0.0 4.1e-42 143.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KNZ71401.1 - 3.8e-14 52.8 3.0 3.8e-14 52.8 0.8 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ71401.1 - 0.0017 18.4 0.1 0.047 13.8 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NIF3 PF01784.18 KNZ71401.1 - 0.037 13.7 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Semialdhyde_dhC PF02774.18 KNZ71401.1 - 0.049 13.7 0.1 0.5 10.4 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 KNZ71401.1 - 0.54 10.2 5.0 0.089 12.7 0.6 2.0 3 0 0 3 3 3 0 Elongation factor Tu domain 4 EphA2_TM PF14575.6 KNZ71402.1 - 0.061 14.2 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 KNZ71402.1 - 0.22 11.0 4.7 0.48 9.9 4.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KNZ71402.1 - 0.63 9.8 4.9 1.1 9.0 4.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DLH PF01738.18 KNZ71403.1 - 1e-17 64.4 0.0 2e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2048 PF09752.9 KNZ71403.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Acetyltransf_1 PF00583.25 KNZ71404.1 - 8.4e-07 29.2 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ71404.1 - 0.038 13.9 0.0 0.091 12.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.8 KNZ71404.1 - 0.15 11.5 0.3 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Elong_Iki1 PF10483.9 KNZ71405.1 - 5.9e-11 42.4 0.0 3.5e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Elongator subunit Iki1 Aminotran_1_2 PF00155.21 KNZ71407.1 - 2e-90 303.6 0.0 2.3e-90 303.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.20 KNZ71408.1 - 9.2e-77 258.2 0.0 1.3e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNZ71408.1 - 7.7e-08 32.2 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KNZ71408.1 - 0.054 13.0 3.4 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Pil1 PF13805.6 KNZ71409.1 - 6.2e-45 153.8 2.0 9.4e-45 153.2 2.0 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 PRKG1_interact PF15898.5 KNZ71409.1 - 6.5 7.7 11.5 2.2 9.3 3.5 3.1 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain IF4E PF01652.18 KNZ71410.1 - 1.9e-50 170.7 0.0 2.7e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mito_carr PF00153.27 KNZ71411.1 - 8.2e-56 185.9 0.8 3.7e-17 62.0 0.1 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein PX PF00787.24 KNZ71412.1 - 7.1e-16 58.2 0.0 1.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 PX domain DivIC PF04977.15 KNZ71412.1 - 2.8 7.8 5.7 1.3 8.9 2.3 2.2 3 0 0 3 3 3 0 Septum formation initiator Methyltransf_23 PF13489.6 KNZ71413.1 - 2.3e-07 30.8 0.0 3.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ71413.1 - 0.002 18.8 0.0 0.0038 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KNZ71413.1 - 0.0041 16.9 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 KNZ71413.1 - 0.0079 16.8 0.0 0.018 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ71413.1 - 0.0082 15.9 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ71413.1 - 0.011 16.5 0.0 0.036 14.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 KNZ71413.1 - 0.028 13.4 0.0 0.067 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 KNZ71413.1 - 0.044 13.1 0.0 0.67 9.2 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase CBS PF00571.28 KNZ71414.1 - 8.5e-24 83.8 3.0 6.7e-10 39.3 0.1 4.8 4 1 1 5 5 5 4 CBS domain SPRY PF00622.28 KNZ71415.1 - 2.7e-19 69.5 0.0 3.8e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain RIO1 PF01163.22 KNZ71418.1 - 6.6e-48 162.8 0.0 1.1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KNZ71418.1 - 1.8e-34 117.8 0.1 3.5e-34 116.9 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KNZ71418.1 - 1e-09 38.7 0.0 0.0009 19.2 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KNZ71418.1 - 9e-08 31.7 0.0 2e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family GNAT_acetyltr_2 PF13718.6 KNZ71418.1 - 0.15 11.4 1.9 0.26 10.7 1.9 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 SRP-alpha_N PF04086.13 KNZ71418.1 - 0.16 11.8 10.9 0.25 11.2 10.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Paf1 PF03985.13 KNZ71418.1 - 0.25 10.3 12.2 0.39 9.7 12.2 1.3 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 KNZ71418.1 - 0.44 8.7 14.6 0.62 8.2 14.6 1.1 1 0 0 1 1 1 0 Nop14-like family SMN PF06003.12 KNZ71418.1 - 0.51 9.6 6.4 0.88 8.8 6.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PARM PF17061.5 KNZ71418.1 - 0.86 9.7 12.1 1.3 9.1 12.1 1.2 1 0 0 1 1 1 0 PARM Lin-8 PF03353.15 KNZ71418.1 - 0.9 9.0 8.4 1.3 8.5 8.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 KNZ71418.1 - 1.9 6.7 14.7 2.6 6.2 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Acetyltransf_1 PF00583.25 KNZ71419.1 - 1.3e-11 44.8 0.1 2.1e-10 40.8 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ71419.1 - 1.4e-05 25.4 0.0 2.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ71419.1 - 2.4e-05 24.3 0.0 0.0011 18.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KNZ71419.1 - 0.0032 17.6 0.0 0.0067 16.5 0.0 1.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KNZ71419.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Ca_bind_SSO6904 PF18249.1 KNZ71419.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Calcium binding protein SSO6904 ESSS PF10183.9 KNZ71420.1 - 5.8e-13 49.0 0.0 6.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2615 PF11027.8 KNZ71420.1 - 0.063 13.4 0.0 0.091 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) GCV_H PF01597.19 KNZ71421.1 - 7e-40 135.7 0.1 8.1e-40 135.5 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 KNZ71421.1 - 1.4e-05 24.9 0.2 2.2e-05 24.3 0.2 1.4 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 KNZ71421.1 - 2.5e-05 24.0 0.1 4.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Peptidase_M23 PF01551.22 KNZ71421.1 - 0.054 13.7 0.2 2.4 8.4 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 RNaseH_C PF09293.10 KNZ71421.1 - 0.2 12.0 0.1 3.9 7.9 0.1 2.2 1 1 0 1 1 1 0 T4 RNase H, C terminal GTP_EFTU PF00009.27 KNZ71422.1 - 4.2e-57 192.9 0.3 6.6e-57 192.2 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KNZ71422.1 - 5.4e-27 94.3 0.1 1.3e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KNZ71422.1 - 7.8e-16 58.2 1.2 1.6e-15 57.2 1.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ71422.1 - 0.00013 22.0 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ71422.1 - 0.0082 16.1 0.1 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 KNZ71422.1 - 0.0085 15.7 0.5 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KNZ71422.1 - 0.029 14.1 0.4 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GRIP PF01465.20 KNZ71423.1 - 1.1e-17 63.6 0.9 4.2e-17 61.8 0.9 2.1 1 0 0 1 1 1 1 GRIP domain Pex14_N PF04695.13 KNZ71423.1 - 3e-15 57.2 0.3 3e-15 57.2 0.3 6.4 4 4 2 7 7 7 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Cation_efflux PF01545.21 KNZ71425.1 - 2.6e-51 174.2 11.3 4.1e-51 173.5 11.3 1.3 1 1 0 1 1 1 1 Cation efflux family DUF2157 PF09925.9 KNZ71425.1 - 0.023 14.5 4.9 0.19 11.5 0.0 3.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SMN PF06003.12 KNZ71426.1 - 1e-08 34.8 2.8 1.4e-08 34.4 2.8 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 KNZ71426.1 - 3.5e-05 23.8 0.0 0.0001 22.3 0.0 1.9 1 1 0 1 1 1 1 Tudor domain Relaxase PF03432.14 KNZ71426.1 - 0.0049 16.5 2.4 0.0095 15.6 2.4 1.4 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain Tudor_3 PF18115.1 KNZ71426.1 - 0.03 14.1 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain FPN1 PF06963.12 KNZ71426.1 - 0.28 9.7 0.4 0.39 9.2 0.4 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3682 PF12446.8 KNZ71426.1 - 0.34 11.4 7.7 0.66 10.4 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Presenilin PF01080.17 KNZ71426.1 - 0.81 8.4 3.6 1 8.1 3.6 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 KNZ71426.1 - 1.1 9.0 2.7 1.6 8.5 2.7 1.3 1 0 0 1 1 1 0 Connexin PDCD2_C PF04194.13 KNZ71426.1 - 1.5 8.9 9.8 0.49 10.4 6.3 1.8 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain FemAB PF02388.16 KNZ71426.1 - 2.4 6.9 9.8 0.11 11.3 4.4 1.5 2 0 0 2 2 2 0 FemAB family Rsc14 PF08586.10 KNZ71426.1 - 5.3 7.9 7.4 46 4.9 5.9 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Jak1_Phl PF17887.1 KNZ71426.1 - 5.6 6.9 9.5 0.94 9.4 5.8 1.6 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain FlaG PF03646.15 KNZ71426.1 - 6.6 7.0 15.2 6.8 6.9 8.9 2.4 2 1 0 2 2 2 0 FlaG protein MDFI PF15316.6 KNZ71426.1 - 8.8 6.4 7.0 14 5.7 2.1 2.1 2 0 0 2 2 2 0 MyoD family inhibitor JAB PF01398.21 KNZ71427.1 - 1.7e-13 50.6 0.0 3.3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DPBB_1 PF03330.18 KNZ71427.1 - 9e-08 32.3 0.5 2e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 Lytic transglycolase UPF0172 PF03665.13 KNZ71427.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DPBB_1 PF03330.18 KNZ71428.1 - 3.2e-09 36.9 0.0 3.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Lytic transglycolase Cerato-platanin PF07249.12 KNZ71428.1 - 0.068 13.3 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 Cerato-platanin Ipi1_N PF12333.8 KNZ71429.1 - 1.3e-21 77.1 0.0 6.1e-20 71.7 0.0 3.4 2 1 2 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation ECH_2 PF16113.5 KNZ71430.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Cellulase PF00150.18 KNZ71431.1 - 2e-17 63.5 0.5 3.2e-17 62.9 0.5 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KNZ71431.1 - 0.0021 17.5 0.1 0.014 14.8 0.1 2.0 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 KNZ71431.1 - 0.014 14.6 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_hydro_2_C PF02836.17 KNZ71431.1 - 0.055 12.6 0.0 0.46 9.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Atracotoxin PF05353.11 KNZ71431.1 - 0.059 13.4 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 Delta Atracotoxin E1_DerP2_DerF2 PF02221.15 KNZ71433.1 - 3.3e-24 85.8 0.1 4.3e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 KNZ71433.1 - 0.00026 21.4 0.0 0.00087 19.7 0.0 1.8 1 1 0 1 1 1 1 ML-like domain Tetraspanin PF00335.20 KNZ71434.1 - 0.011 15.5 10.1 0.035 13.8 10.1 1.8 1 1 0 1 1 1 0 Tetraspanin family MRAP PF15183.6 KNZ71434.1 - 0.026 14.4 0.1 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF2749 PF10907.8 KNZ71434.1 - 0.52 10.5 5.0 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) Ribosomal_L17 PF01196.19 KNZ71437.1 - 2.4e-34 118.1 0.0 5.3e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L17 SGL PF08450.12 KNZ71438.1 - 2.1e-70 237.1 0.0 2.5e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KNZ71438.1 - 1.2e-05 25.4 0.0 0.00016 21.8 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 KNZ71438.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 Strictosidine synthase DUF4221 PF13970.6 KNZ71438.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) Ribosomal_L13 PF00572.18 KNZ71439.1 - 1.2e-11 44.9 0.0 7.7e-10 39.1 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 KH_1 PF00013.29 KNZ71440.1 - 7.8e-42 140.9 9.7 8.3e-16 57.6 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KNZ71440.1 - 8.1e-11 41.6 0.9 0.002 17.9 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 KNZ71440.1 - 7.1e-08 32.2 8.0 0.029 14.2 0.1 3.5 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 KNZ71440.1 - 3.7e-05 23.7 3.8 0.1 12.7 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.19 KNZ71440.1 - 0.038 13.7 0.3 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 dUTPase NUFIP1 PF10453.9 KNZ71441.1 - 3.4e-17 62.0 2.0 7.9e-17 60.8 2.0 1.7 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) PARM PF17061.5 KNZ71441.1 - 0.13 12.3 7.2 0.22 11.7 7.2 1.2 1 0 0 1 1 1 0 PARM Pinin_SDK_N PF04697.13 KNZ71441.1 - 0.25 12.0 9.1 0.54 10.9 8.8 1.7 1 1 1 2 2 2 0 pinin/SDK conserved region API5 PF05918.11 KNZ71441.1 - 0.41 9.4 1.8 0.55 9.0 1.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SSFA2_C PF14723.6 KNZ71441.1 - 1.5 8.7 4.4 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus IDO PF01231.18 KNZ71442.1 - 1.4e-133 445.8 0.0 1.7e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Peptidase_M16_C PF05193.21 KNZ71443.1 - 5.7e-16 59.1 0.0 3.9e-12 46.6 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KNZ71443.1 - 4e-09 36.6 0.0 3.1e-08 33.7 0.0 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 KNZ71443.1 - 0.016 14.4 0.2 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16C associated MCM_N PF14551.6 KNZ71443.1 - 0.15 12.7 0.0 37 5.0 0.0 2.9 3 0 0 3 3 3 0 MCM N-terminal domain DUF2205 PF10224.9 KNZ71443.1 - 0.45 10.6 3.0 1.5 8.9 1.4 2.4 2 0 0 2 2 2 0 Short coiled-coil protein Exo_endo_phos PF03372.23 KNZ71444.1 - 2.5e-19 69.7 0.0 5.1e-19 68.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA_NucTransf2 PF09249.11 KNZ71444.1 - 0.18 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain RhoGEF PF00621.20 KNZ71445.1 - 2.1e-17 64.0 0.0 4.3e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Coat_F PF07875.12 KNZ71445.1 - 0.26 11.5 0.3 0.93 9.8 0.1 1.9 2 0 0 2 2 2 0 Coat F domain Fungal_trans PF04082.18 KNZ71447.1 - 2.1e-06 27.0 0.2 4.1e-06 26.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ71447.1 - 5e-06 26.5 10.8 8.9e-06 25.7 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-E PF04168.12 KNZ71449.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Ras PF00071.22 KNZ71450.1 - 1.3e-47 161.4 0.1 1.5e-47 161.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ71450.1 - 4.1e-17 62.5 0.0 6.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KNZ71450.1 - 0.00067 19.6 0.1 0.23 11.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KNZ71450.1 - 0.0015 18.1 0.0 0.0048 16.5 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KNZ71450.1 - 0.0034 16.9 0.1 0.13 11.8 0.0 2.6 1 1 1 3 3 3 1 Ferrous iron transport protein B NB-ARC PF00931.22 KNZ71450.1 - 0.012 14.9 0.1 0.016 14.4 0.1 1.6 1 1 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KNZ71450.1 - 0.051 13.7 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 KNZ71450.1 - 0.057 13.1 0.1 0.14 11.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 KNZ71450.1 - 0.06 13.7 0.6 0.17 12.3 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain Gly_kinase PF02595.15 KNZ71450.1 - 0.15 11.1 0.0 1 8.3 0.0 1.9 2 0 0 2 2 2 0 Glycerate kinase family Yippee-Mis18 PF03226.14 KNZ71451.1 - 1.1e-14 54.6 0.2 1.2e-14 54.4 0.2 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-UBR PF02207.20 KNZ71451.1 - 0.0078 16.4 1.1 3.1 8.0 0.2 2.2 2 0 0 2 2 2 2 Putative zinc finger in N-recognin (UBR box) AlcCBM31 PF11606.8 KNZ71451.1 - 0.072 13.3 0.1 2.2 8.5 0.0 2.1 1 1 0 2 2 2 0 Family 31 carbohydrate binding protein Evr1_Alr PF04777.13 KNZ71451.1 - 0.15 12.5 0.2 1.2 9.7 0.2 2.0 1 1 0 1 1 1 0 Erv1 / Alr family Helicase_C PF00271.31 KNZ71452.1 - 3.2e-15 56.4 0.1 7.7e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ71452.1 - 4.3e-07 30.1 0.0 1.5e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNZ71452.1 - 4.8e-05 23.2 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KNZ71452.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 SWI2/SNF2 ATPase TniB PF05621.11 KNZ71452.1 - 0.042 13.3 0.1 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Beta_elim_lyase PF01212.21 KNZ71454.1 - 1.4e-71 241.2 0.0 2.1e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KNZ71454.1 - 0.00029 19.5 0.0 0.0005 18.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-met2 PF12907.7 KNZ71455.1 - 5.4e-15 55.2 0.7 8e-15 54.7 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KNZ71455.1 - 0.00048 20.9 11.8 0.00075 20.3 11.8 1.3 1 0 0 1 1 1 1 4F5 protein family zf-Tim10_DDP PF02953.15 KNZ71456.1 - 2.2e-18 65.7 0.7 2.4e-18 65.5 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 KNZ71456.1 - 0.18 11.8 1.3 0.28 11.2 1.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) WD40 PF00400.32 KNZ71457.1 - 1.6e-11 44.5 22.3 0.0026 18.5 0.1 9.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ71457.1 - 4.1e-08 33.4 0.2 0.0094 16.2 0.0 6.3 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BAT PF15915.5 KNZ71457.1 - 0.023 14.6 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Frtz PF11768.8 KNZ71457.1 - 0.025 12.9 0.0 0.041 12.2 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KNZ71457.1 - 0.38 10.8 2.9 9.7 6.3 0.1 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Mpv17_PMP22 PF04117.12 KNZ71458.1 - 1.5e-22 79.6 0.1 2.2e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.16 KNZ71460.1 - 1.7e-39 134.8 0.2 2e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.29 KNZ71461.1 - 1.9e-40 138.5 0.1 3.3e-40 137.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ71461.1 - 3.4e-24 85.3 0.0 2.9e-23 82.3 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KNZ71461.1 - 1.6e-18 66.7 0.3 3.1e-18 65.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 KNZ71461.1 - 0.033 14.4 1.1 0.78 10.0 0.2 3.0 2 1 0 2 2 2 0 AAA domain UPF0121 PF03661.13 KNZ71462.1 - 3.5e-38 131.4 9.6 4.1e-38 131.2 9.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CBS PF00571.28 KNZ71463.1 - 1e-35 122.0 4.9 4.8e-10 39.7 0.0 4.8 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 KNZ71463.1 - 4.9e-08 32.8 0.0 1.7e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 PB1 domain ATPase PF06745.13 KNZ71463.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Sgf11 PF08209.11 KNZ71464.1 - 5.3e-13 48.3 0.5 1.2e-12 47.1 0.5 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 KNZ71464.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain zf-RING_5 PF14634.6 KNZ71464.1 - 0.95 9.5 2.9 3.2 7.8 0.4 2.2 2 0 0 2 2 2 0 zinc-RING finger domain PTH2 PF01981.16 KNZ71465.1 - 1.1e-40 138.5 0.2 1.2e-40 138.4 0.2 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SUR7 PF06687.12 KNZ71466.1 - 0.019 14.6 0.6 0.019 14.6 0.6 2.4 3 1 0 3 3 3 0 SUR7/PalI family PHO4 PF01384.20 KNZ71466.1 - 0.21 10.6 4.0 0.11 11.5 0.4 1.9 2 0 0 2 2 2 0 Phosphate transporter family DUF4834 PF16118.5 KNZ71466.1 - 0.37 11.8 0.9 1.2 10.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Use1 PF09753.9 KNZ71467.1 - 0.051 13.3 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Urocanase PF01175.18 KNZ71467.1 - 0.15 11.7 0.0 17 5.0 0.0 2.1 2 0 0 2 2 2 0 Urocanase Rossmann-like domain Synaptobrevin PF00957.21 KNZ71467.1 - 0.43 10.4 2.2 0.33 10.8 0.5 1.6 2 0 0 2 2 2 0 Synaptobrevin Peptidase_C48 PF02902.19 KNZ71468.1 - 6.2e-20 72.0 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PRKG1_interact PF15898.5 KNZ71468.1 - 0.41 11.6 3.9 1.3 9.9 3.9 1.8 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain G-patch PF01585.23 KNZ71469.1 - 5.5e-11 42.2 0.1 1.1e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 KNZ71469.1 - 5.2e-07 29.8 6.2 8.9e-07 29.0 6.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ71469.1 - 1.8e-05 24.9 1.5 3e-05 24.3 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 KNZ71469.1 - 0.00019 21.4 0.1 0.00019 21.4 0.1 2.1 2 0 0 2 2 2 1 G-patch domain zf-C2H2_2 PF12756.7 KNZ71469.1 - 0.0014 19.0 0.7 0.0023 18.2 0.7 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 KNZ71469.1 - 0.0079 16.3 0.4 0.012 15.8 0.4 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger DUF4820 PF16091.5 KNZ71469.1 - 0.099 12.0 6.5 0.14 11.5 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNA_pol3_a_NII PF11490.8 KNZ71469.1 - 0.82 9.6 6.2 5.8 6.8 0.2 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Frataxin_Cyay PF01491.16 KNZ71471.1 - 1.1e-37 128.3 0.0 1.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain Drf_DAD PF06345.11 KNZ71471.1 - 0.13 12.3 0.7 0.32 11.1 0.7 1.6 1 0 0 1 1 1 0 DRF Autoregulatory Domain Urb2 PF10441.9 KNZ71472.1 - 3.4e-41 141.4 0.1 3.4e-41 141.4 0.1 3.1 3 1 0 3 3 3 1 Urb2/Npa2 family Peroxin-3 PF04882.12 KNZ71472.1 - 0.0053 15.8 0.3 0.014 14.4 0.1 1.8 2 0 0 2 2 2 1 Peroxin-3 SPO22 PF08631.10 KNZ71472.1 - 0.26 10.7 4.5 1.8 8.0 0.2 3.5 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like IBR PF01485.21 KNZ71473.1 - 1e-18 67.3 31.9 1.8e-11 44.1 1.9 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain RWD PF05773.22 KNZ71473.1 - 1.9e-09 37.8 0.1 5.4e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.6 KNZ71473.1 - 0.00045 20.5 8.8 0.00045 20.5 8.8 4.8 4 1 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 KNZ71473.1 - 0.00058 19.8 9.2 0.00058 19.8 9.2 4.2 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KNZ71473.1 - 0.00075 19.3 6.8 0.00075 19.3 6.8 4.8 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ71473.1 - 0.015 15.3 9.2 0.015 15.3 9.2 4.4 3 2 1 4 4 4 0 zinc-RING finger domain KH_1 PF00013.29 KNZ71474.1 - 5.3e-41 138.3 0.3 3.6e-10 39.5 0.0 7.3 7 0 0 7 7 7 6 KH domain V-ATPase_C PF03223.15 KNZ71475.1 - 1.9e-129 432.3 2.1 2.2e-129 432.1 2.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Rhodanese PF00581.20 KNZ71476.1 - 1.4e-17 64.1 0.0 1.1e-09 38.8 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain ACP_syn_III_C PF08541.10 KNZ71476.1 - 0.15 12.3 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ctr PF04145.15 KNZ71480.1 - 5.9e-30 104.8 0.0 6.7e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Rhodanese PF00581.20 KNZ71481.1 - 2.9e-14 53.5 0.0 5.4e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Multi_ubiq PF14452.6 KNZ71481.1 - 0.03 14.5 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 Multiubiquitin PWI PF01480.17 KNZ71482.1 - 1.4e-08 34.9 0.0 2.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KNZ71482.1 - 2.2e-06 27.4 4.9 3.6e-06 26.7 4.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNZ71482.1 - 0.0011 19.0 7.3 0.0018 18.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger domain FXMRP1_C_core PF12235.8 KNZ71482.1 - 0.012 16.2 3.2 0.012 16.2 3.2 3.6 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal PRKG1_interact PF15898.5 KNZ71482.1 - 0.05 14.5 6.0 0.1 13.5 6.0 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain RRM_3 PF08777.11 KNZ71482.1 - 0.053 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 RNA binding motif Pannexin_like PF12534.8 KNZ71482.1 - 0.15 11.1 1.3 0.22 10.5 1.3 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 zf-CCCH_2 PF14608.6 KNZ71482.1 - 1.1 9.8 3.0 1.9 9.1 3.0 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger AKNA PF12443.8 KNZ71483.1 - 0.17 12.6 0.3 4.1 8.1 0.0 2.3 1 1 0 2 2 2 0 AT-hook-containing transcription factor Lsm_interact PF05391.11 KNZ71484.1 - 0.5 9.9 4.2 1.8 8.2 1.3 2.6 2 0 0 2 2 2 0 Lsm interaction motif Aminotran_4 PF01063.19 KNZ71485.1 - 3.1e-31 109.0 0.0 4.4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV APH PF01636.23 KNZ71488.1 - 2.9e-10 40.5 0.6 1.8e-09 37.9 0.6 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ71488.1 - 1e-05 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ71488.1 - 0.014 15.0 0.1 0.17 11.5 0.0 2.2 2 1 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KNZ71488.1 - 0.025 14.0 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Aldedh PF00171.22 KNZ71489.1 - 4e-178 592.7 0.8 4.5e-178 592.5 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KNZ71489.1 - 0.022 14.2 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) LuxC PF05893.14 KNZ71489.1 - 0.079 12.0 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) ADH_zinc_N PF00107.26 KNZ71490.1 - 5.8e-22 78.1 0.1 9.9e-22 77.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ71490.1 - 2.2e-18 66.1 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KNZ71490.1 - 0.00044 21.3 0.0 0.00076 20.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KNZ71490.1 - 0.017 14.9 0.2 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) NTP_transf_2 PF01909.23 KNZ71491.1 - 1.6e-07 31.5 0.0 4.7e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KNZ71491.1 - 3.4e-07 30.4 0.1 6.6e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KNZ71491.1 - 0.00049 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DUF249 PF03158.13 KNZ71492.1 - 0.22 11.2 0.2 0.39 10.4 0.2 1.3 1 0 0 1 1 1 0 Multigene family 530 protein MLVIN_C PF18697.1 KNZ71496.1 - 0.03 14.4 0.3 0.17 12.0 0.1 2.2 2 1 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVP_2 PF08284.11 KNZ71497.1 - 5.5e-05 23.0 0.0 6.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Colicin_Pyocin PF01320.18 KNZ71498.1 - 0.088 12.9 0.1 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein Coat_X PF07552.11 KNZ71501.1 - 0.05 13.4 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 Spore Coat Protein X and V domain Abhydrolase_6 PF12697.7 KNZ71502.1 - 2.9e-07 31.3 0.0 3.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chromo PF00385.24 KNZ71503.1 - 1.9e-16 59.7 0.0 2.4e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ71503.1 - 0.04 14.1 0.1 0.058 13.6 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 GED PF02212.18 KNZ71504.1 - 0.15 12.2 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain E1_dh PF00676.20 KNZ71505.1 - 1.5e-109 365.6 0.0 1.7e-109 365.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KNZ71505.1 - 5.1e-05 22.6 0.0 8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KNZ71505.1 - 0.00022 21.0 0.6 0.00022 21.0 0.6 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PIF1 PF05970.14 KNZ71506.1 - 7.8e-34 117.4 0.0 8.8e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ71506.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Ferlin_C PF16165.5 KNZ71508.1 - 0.062 13.2 0.1 0.088 12.7 0.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus RsbU_N PF08673.10 KNZ71509.1 - 0.036 14.2 0.1 0.075 13.1 0.0 1.7 1 1 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain gag-asp_proteas PF13975.6 KNZ71510.1 - 0.00075 20.0 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ71510.1 - 0.0024 18.5 0.0 0.0054 17.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease POT1PC PF16686.5 KNZ71511.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Methyltransf_2 PF00891.18 KNZ71512.1 - 1.7e-13 50.4 0.0 2.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KNZ71512.1 - 0.02 15.6 0.0 0.15 12.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain RPA_C PF08784.11 KNZ71512.1 - 0.045 14.4 0.0 0.092 13.4 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal MarR_2 PF12802.7 KNZ71512.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 MarR family CCAP PF11105.8 KNZ71512.1 - 0.11 12.4 0.2 6 6.8 0.0 2.3 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a Rrf2 PF02082.20 KNZ71512.1 - 0.15 12.5 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Dimerisation PF08100.11 KNZ71512.1 - 0.18 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain SMN PF06003.12 KNZ71515.1 - 0.13 11.5 0.6 0.17 11.1 0.6 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Mitofilin PF09731.9 KNZ71516.1 - 1.6e-86 291.6 18.2 1.7e-86 291.5 18.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF494 PF04361.13 KNZ71516.1 - 1 9.2 7.3 0.27 11.1 3.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF494) DUF4795 PF16043.5 KNZ71516.1 - 1.8 8.1 8.6 19 4.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) MnmE_helical PF12631.7 KNZ71516.1 - 3.9 7.6 9.4 9.2 6.4 9.4 1.8 1 1 0 1 1 1 0 MnmE helical domain DHQ_synthase PF01761.20 KNZ71517.1 - 6.8e-36 123.8 0.4 1.3e-35 122.9 0.4 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase USP8_interact PF08941.10 KNZ71517.1 - 0.036 13.9 0.2 0.08 12.7 0.0 1.6 2 0 0 2 2 2 0 USP8 interacting FMO-like PF00743.19 KNZ71520.1 - 2.7e-13 49.2 0.0 4.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ71520.1 - 4.6e-11 42.5 0.0 7.9e-09 35.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ71520.1 - 1.1e-08 35.2 0.0 4e-08 33.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KNZ71520.1 - 4.4e-08 32.7 0.0 5.9e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ71520.1 - 2.6e-07 30.1 0.0 0.00044 19.5 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KNZ71520.1 - 0.00016 21.4 0.0 0.31 10.6 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ71520.1 - 0.00017 21.6 0.1 0.019 15.0 0.0 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ71520.1 - 0.011 16.3 0.8 3.9 8.1 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ71520.1 - 0.12 11.6 0.2 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 KNZ71520.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.4 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KNZ71520.1 - 0.23 10.1 0.1 0.45 9.1 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Alanine_zipper PF11839.8 KNZ71522.1 - 2.3e-05 24.7 67.1 1.1 9.7 11.2 4.9 1 1 5 6 6 6 6 Alanine-zipper, major outer membrane lipoprotein Pex24p PF06398.11 KNZ71522.1 - 1.5 7.7 2.8 2.3 7.1 2.8 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Exo_endo_phos_2 PF14529.6 KNZ71523.1 - 0.00017 21.4 0.5 0.00017 21.4 0.5 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KNZ71524.1 - 8.5e-05 22.2 0.0 0.0001 21.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pyr_redox_2 PF07992.14 KNZ71526.1 - 6.3e-06 25.6 0.0 7.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KNZ71526.1 - 9.2e-06 24.3 0.0 1.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KNZ71526.1 - 0.00073 18.8 0.0 0.029 13.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KNZ71526.1 - 0.0049 16.2 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KNZ71526.1 - 0.013 14.8 0.0 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ71526.1 - 0.17 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RVP_2 PF08284.11 KNZ71527.1 - 0.093 12.5 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease OTT_1508_deam PF14441.6 KNZ71528.1 - 2.1e-07 30.8 0.0 5.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF3863 PF12979.7 KNZ71528.1 - 0.058 12.2 0.0 2.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) OTT_1508_deam PF14441.6 KNZ71529.1 - 9.6e-09 35.1 0.1 2.8e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase SusD_RagB PF07980.11 KNZ71529.1 - 0.071 12.7 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 SusD family DUF3258 PF11646.8 KNZ71529.1 - 0.24 11.5 2.1 5.4 7.2 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF3258 BCIP PF13862.6 KNZ71530.1 - 3.5e-34 118.4 0.2 1.1e-33 116.7 0.0 1.7 2 0 0 2 2 2 1 p21-C-terminal region-binding protein Pro_dh PF01619.18 KNZ71531.1 - 7.1e-53 180.1 0.0 2.2e-52 178.4 0.0 1.7 1 1 0 1 1 1 1 Proline dehydrogenase DUF4817 PF16087.5 KNZ71532.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain (DUF4817) Phage_GP20 PF06810.11 KNZ71532.1 - 5 6.9 14.4 0.56 10.0 3.0 2.5 1 1 0 2 2 2 0 Phage minor structural protein GP20 COesterase PF00135.28 KNZ71533.1 - 5.9e-06 25.4 0.0 8.1e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Coprogen_oxidas PF01218.18 KNZ71534.1 - 2.1e-131 437.0 0.0 2.4e-131 436.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SAICAR_synt PF01259.18 KNZ71535.1 - 2.1e-101 338.8 0.0 2.6e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase MucBP PF06458.12 KNZ71536.1 - 0.12 13.4 0.6 0.5 11.4 0.0 2.0 2 0 0 2 2 2 0 MucBP domain LodA_C PF18417.1 KNZ71536.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 L-lysine epsilon oxidase C-terminal domain Diphthamide_syn PF01866.17 KNZ71537.1 - 1.3e-81 274.4 0.2 5.8e-81 272.2 0.2 1.8 1 1 0 1 1 1 1 Putative diphthamide synthesis protein DUF4746 PF15928.5 KNZ71537.1 - 0.16 11.3 0.0 0.57 9.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) CEP209_CC5 PF16574.5 KNZ71538.1 - 0.033 14.3 1.4 0.046 13.9 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 Phage_integrase PF00589.22 KNZ71542.1 - 9.1e-05 22.3 0.0 0.0006 19.7 0.0 2.2 3 0 0 3 3 3 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KNZ71542.1 - 0.059 13.7 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Coatomer_g_Cpla PF16381.5 KNZ71544.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Coatomer subunit gamma-1 C-terminal appendage platform Glyco_hydro_31 PF01055.26 KNZ71545.1 - 3.6e-114 382.4 0.7 4.5e-114 382.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KNZ71545.1 - 2.3e-09 37.4 0.1 1.2e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 KNZ71545.1 - 0.22 11.8 0.0 0.73 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4968) Cmc1 PF08583.10 KNZ71546.1 - 1.7e-14 53.6 2.4 2e-14 53.3 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Cation_ATPase_N PF00690.26 KNZ71546.1 - 0.054 13.2 0.1 0.084 12.6 0.1 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus DUF3128 PF11326.8 KNZ71546.1 - 0.99 9.8 4.9 2.6 8.5 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Transketolase_N PF00456.21 KNZ71547.1 - 3.9e-149 496.1 0.1 5e-149 495.8 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KNZ71547.1 - 1.1e-42 145.7 0.0 2.4e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KNZ71547.1 - 6.8e-14 51.8 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 KNZ71547.1 - 0.00049 19.4 0.2 0.00095 18.4 0.2 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 KNZ71547.1 - 0.0021 17.0 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.21 KNZ71547.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain UCR_14kD PF02271.16 KNZ71548.1 - 1.3e-38 131.0 0.7 1.5e-38 130.8 0.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit NDK PF00334.19 KNZ71549.1 - 4.3e-55 185.4 0.0 5.1e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CDH-cyt PF16010.5 KNZ71550.1 - 3.2e-08 33.5 0.2 1.2e-07 31.6 0.2 1.9 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 KNZ71550.1 - 6e-05 23.3 0.0 0.00028 21.1 0.0 2.0 3 0 0 3 3 3 1 DOMON domain Cytochrom_B561 PF03188.16 KNZ71550.1 - 0.00013 22.1 6.2 0.00025 21.2 6.2 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Pyridoxal_deC PF00282.19 KNZ71551.1 - 1.6e-57 194.9 0.0 7.5e-57 192.7 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KNZ71551.1 - 1.7e-05 23.9 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KNZ71551.1 - 0.067 11.9 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain VIT_2 PF13757.6 KNZ71552.1 - 0.0036 17.2 0.1 0.01 15.7 0.1 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain COX7a PF02238.15 KNZ71552.1 - 0.41 11.1 0.0 0.41 11.1 0.0 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII Pyridoxal_deC PF00282.19 KNZ71554.1 - 4.1e-66 223.2 0.0 5.3e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KNZ71554.1 - 3.4e-07 29.6 0.0 6.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KNZ71554.1 - 0.07 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain 4HBT PF03061.22 KNZ71555.1 - 1.8e-08 34.6 0.0 2.5e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KNZ71555.1 - 0.0003 20.1 0.1 0.00058 19.2 0.2 1.4 2 0 0 2 2 2 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 KNZ71555.1 - 0.00035 21.0 0.0 0.00044 20.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Pet100 PF09803.9 KNZ71556.1 - 2.1e-26 92.2 0.0 2.9e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Pet100 PALP PF00291.25 KNZ71557.1 - 8.2e-55 186.3 0.0 9.8e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PIN_4 PF13638.6 KNZ71558.1 - 1.4e-20 73.9 0.0 3e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.9 KNZ71558.1 - 9.9e-08 31.8 0.0 1.8e-06 27.7 0.0 2.5 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 KNZ71558.1 - 0.17 12.2 0.1 2.7 8.3 0.0 2.4 2 0 0 2 2 2 0 PIN like domain zf-RVT PF13966.6 KNZ71559.1 - 0.00014 22.5 0.4 0.00014 22.5 0.4 2.7 3 1 0 3 3 3 1 zinc-binding in reverse transcriptase DNA_pol_D_N PF18018.1 KNZ71560.1 - 3.1e-42 143.7 0.0 4.7e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 KNZ71560.1 - 1.2e-30 106.4 0.0 2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B EAP30 PF04157.16 KNZ71561.1 - 1.4e-71 240.5 0.1 1.6e-71 240.3 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4423 PF14394.6 KNZ71561.1 - 0.027 14.2 0.1 0.12 12.0 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4423) Endotoxin_N PF03945.14 KNZ71561.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Cellulase PF00150.18 KNZ71563.1 - 3.3e-23 82.5 2.0 5.1e-23 81.9 2.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) VOMI PF03762.17 KNZ71563.1 - 0.023 14.8 1.4 0.068 13.3 1.4 1.8 1 1 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) Hid1 PF12722.7 KNZ71564.1 - 1.5e-174 582.3 0.0 1.8e-174 582.1 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KNZ71564.1 - 4.1e-89 299.7 0.0 5.4e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Thioredoxin_9 PF14595.6 KNZ71564.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Rad51 PF08423.11 KNZ71565.1 - 1.8e-32 112.6 0.0 2.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KNZ71565.1 - 1.8e-05 24.4 0.2 0.0026 17.3 0.1 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_25 PF13481.6 KNZ71565.1 - 7.4e-05 22.4 0.0 0.00023 20.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain DnaB_C PF03796.15 KNZ71565.1 - 0.00045 19.6 0.2 0.0051 16.2 0.2 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 KNZ71565.1 - 0.00046 19.6 0.0 0.00074 18.9 0.0 1.4 1 0 0 1 1 1 1 KaiC Atg8 PF02991.16 KNZ71566.1 - 6.1e-52 174.1 0.2 7.3e-52 173.9 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KNZ71566.1 - 3.9e-07 30.4 0.0 4.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.17 KNZ71566.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Variant SH3 domain Band_7 PF01145.25 KNZ71567.1 - 5.1e-05 23.4 0.0 5.1e-05 23.4 0.0 3.0 2 1 0 3 3 3 1 SPFH domain / Band 7 family FlgT_C PF16538.5 KNZ71567.1 - 0.51 10.9 4.4 5 7.7 0.4 2.8 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain Lactamase_B_2 PF12706.7 KNZ71568.1 - 1e-07 31.7 0.2 0.0025 17.4 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KNZ71568.1 - 9.6e-05 22.5 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KNZ71568.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II MFS_1 PF07690.16 KNZ71569.1 - 1.2e-34 119.8 32.9 1.2e-34 119.8 32.9 2.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Pkinase PF00069.25 KNZ71570.1 - 2e-65 220.8 0.0 2.3e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71570.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ71570.1 - 4.9e-05 22.8 0.0 0.00025 20.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KNZ71570.1 - 0.00095 19.2 0.1 0.04 13.8 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ71570.1 - 0.019 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 KNZ71570.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KNZ71570.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KNZ71571.1 - 1e-46 155.9 27.8 3.9e-08 33.8 0.3 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KNZ71571.1 - 1.3e-11 44.2 0.2 2.7e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KNZ71571.1 - 2.3e-11 43.0 14.6 0.0032 16.2 0.1 6.1 2 2 2 6 6 6 6 Nucleoporin Nup120/160 F-box PF00646.33 KNZ71571.1 - 1.3e-09 37.7 0.0 2.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KNZ71571.1 - 2e-07 31.2 1.3 4.8 7.5 0.0 5.4 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KNZ71571.1 - 0.0049 16.7 0.0 0.017 15.0 0.0 2.0 1 0 0 1 1 1 1 F-box DUF866 PF05907.13 KNZ71572.1 - 0.0063 16.4 1.4 0.0092 15.9 1.4 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PARM PF17061.5 KNZ71572.1 - 0.048 13.8 1.6 0.067 13.3 1.6 1.2 1 0 0 1 1 1 0 PARM Thoc2 PF11732.8 KNZ71573.1 - 0.035 14.2 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Plavaka PF18759.1 KNZ71574.1 - 3.1e-07 29.9 0.0 5.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase UQ_con PF00179.26 KNZ71576.1 - 6.7e-12 45.2 0.2 3.5e-09 36.4 0.4 2.2 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Cul7 PF11515.8 KNZ71576.1 - 0.039 14.2 0.0 0.075 13.3 0.0 1.4 2 0 0 2 2 2 0 Mouse development and cellular proliferation protein Cullin-7 ALO PF04030.14 KNZ71577.1 - 4.6e-72 242.9 4.8 1.6e-71 241.2 4.8 1.7 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KNZ71577.1 - 0.0001 22.0 0.4 0.00022 21.0 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain DDE_Tnp_1_assoc PF13808.6 KNZ71577.1 - 0.088 12.8 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 DDE_Tnp_1-associated CRF-BP PF05428.11 KNZ71578.1 - 0.16 10.8 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Corticotropin-releasing factor binding protein (CRF-BP) PapG_C PF03628.13 KNZ71579.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 PapG chaperone-binding domain DUF2971 PF11185.8 KNZ71579.1 - 0.048 14.8 0.1 0.21 12.7 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2971) Dpoe2NT PF12213.8 KNZ71580.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Calcipressin PF04847.12 KNZ71582.1 - 6.1 6.5 9.2 22 4.7 9.1 1.8 1 1 1 2 2 2 0 Calcipressin WD40 PF00400.32 KNZ71584.1 - 0.00031 21.5 1.7 0.94 10.5 0.2 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat T4_deiodinase PF00837.17 KNZ71584.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Glyco_hydro_115 PF15979.5 KNZ71585.1 - 6.4e-06 25.8 0.0 8.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 Peptidase_C54 PF03416.19 KNZ71586.1 - 1.1e-101 339.9 0.0 1.5e-101 339.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 FAM176 PF14851.6 KNZ71586.1 - 8.3 6.1 7.3 13 5.4 4.5 2.3 2 0 0 2 2 2 0 FAM176 family p450 PF00067.22 KNZ71587.1 - 3.3e-58 197.6 0.0 4.6e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM150 PF15129.6 KNZ71588.1 - 0.2 11.8 0.2 0.26 11.4 0.2 1.2 1 0 0 1 1 1 0 FAM150 family MFS_1 PF07690.16 KNZ71589.1 - 0.00052 19.0 8.8 0.00055 19.0 8.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2830 PF11125.8 KNZ71590.1 - 0.02 14.9 1.6 0.029 14.3 1.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2830) Ribonuclease_3 PF00636.26 KNZ71591.1 - 2.1e-37 128.0 0.0 5e-18 65.7 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KNZ71591.1 - 1.8e-25 89.6 0.3 2.3e-10 40.7 0.0 4.5 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.14 KNZ71591.1 - 8.1e-23 80.4 0.0 2e-22 79.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 KNZ71591.1 - 2.6e-14 53.5 0.1 1.3e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNZ71591.1 - 5.7e-14 52.3 0.0 1.4e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KNZ71591.1 - 3.3e-12 46.7 0.0 6.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dzip-like_N PF13815.6 KNZ71591.1 - 0.13 12.2 0.1 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal PvlArgDC PF01862.16 KNZ71591.1 - 0.15 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Peroxidase_2 PF01328.17 KNZ71592.1 - 8.9e-50 169.8 0.0 1.1e-49 169.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Zot PF05707.12 KNZ71592.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) adh_short PF00106.25 KNZ71593.1 - 3e-37 128.0 0.0 4e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ71593.1 - 2.6e-25 89.3 0.0 3.4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ71593.1 - 2.1e-06 27.8 0.0 2.9e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KNZ71593.1 - 1.4e-05 24.7 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KNZ71593.1 - 0.00017 21.1 0.0 0.00024 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KNZ71593.1 - 0.0024 17.0 0.1 0.0037 16.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KNZ71593.1 - 0.0099 15.8 0.2 0.013 15.4 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KNZ71593.1 - 0.025 13.7 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 KNZ71593.1 - 0.035 13.7 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Protoglobin PF11563.8 KNZ71594.1 - 4.3e-44 150.2 0.0 5e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Protoglobin p450 PF00067.22 KNZ71595.1 - 1.4e-61 208.7 0.0 1.8e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_30 PF02055.16 KNZ71597.1 - 9e-30 103.8 0.7 1.2e-29 103.5 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 KNZ71597.1 - 1.3e-15 57.4 0.3 2.5e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KNZ71597.1 - 4.6e-05 23.2 0.0 0.0011 18.7 0.0 2.2 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 MFS_1 PF07690.16 KNZ71599.1 - 1.7e-39 135.7 34.2 1.7e-39 135.7 34.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Bacteriocin_IId PF09221.10 KNZ71599.1 - 2.6 8.3 8.0 0.5 10.6 0.9 2.6 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Fasciclin PF02469.22 KNZ71600.1 - 2e-30 105.6 1.9 1.5e-18 67.2 0.4 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF5373 PF17343.2 KNZ71601.1 - 0.067 13.0 3.5 0.038 13.8 1.6 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5373) DUF2207 PF09972.9 KNZ71601.1 - 0.33 9.6 1.3 0.78 8.4 1.4 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) EcsB PF05975.12 KNZ71601.1 - 0.52 9.1 9.7 12 4.6 9.3 2.1 1 1 1 2 2 2 0 Bacterial ABC transporter protein EcsB ABC2_membrane_3 PF12698.7 KNZ71601.1 - 1.2 8.2 8.7 1.8 7.6 8.7 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein NdhL PF10716.9 KNZ71601.1 - 3.4 7.7 9.4 3.1 7.8 0.0 3.1 2 1 1 3 3 3 0 NADH dehydrogenase transmembrane subunit DUF3899 PF13038.6 KNZ71601.1 - 8.3 7.0 13.5 6.2e+03 -2.2 13.0 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) F-box-like PF12937.7 KNZ71602.1 - 6e-08 32.5 1.2 2.3e-07 30.6 1.2 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ71602.1 - 0.32 10.9 1.9 7.3 6.6 0.4 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 KNZ71603.1 - 1.1e-05 25.3 1.3 3.7e-05 23.5 1.3 2.0 1 0 0 1 1 1 1 F-box-like PP2C PF00481.21 KNZ71604.1 - 4.5e-50 170.7 0.2 8.5e-50 169.8 0.2 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C HMG_box PF00505.19 KNZ71605.1 - 4.1e-07 30.3 3.8 9.1e-07 29.2 3.8 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box DUF5007 PF16398.5 KNZ71605.1 - 0.045 13.4 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) adh_short PF00106.25 KNZ71606.1 - 2.7e-35 121.6 0.2 5.2e-35 120.7 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ71606.1 - 1.1e-22 80.7 1.6 1.5e-21 77.0 1.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KNZ71606.1 - 0.0023 17.4 0.1 0.0037 16.7 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Integrase_H2C2 PF17921.1 KNZ71609.1 - 2.3e-11 43.6 6.7 5.2e-11 42.5 6.7 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain HMG_box PF00505.19 KNZ71610.1 - 4.2e-05 23.9 6.6 0.00013 22.3 6.6 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box PNP_UDP_1 PF01048.20 KNZ71611.1 - 3.7e-25 88.6 0.0 8.3e-25 87.4 0.0 1.5 1 1 1 2 2 2 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.13 KNZ71611.1 - 0.16 11.9 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.19 KNZ71612.1 - 0.016 15.6 4.4 0.021 15.2 1.3 2.2 1 1 1 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ71612.1 - 0.026 15.1 2.3 0.77 10.4 3.2 2.3 1 1 1 2 2 2 0 HMG-box domain adh_short_C2 PF13561.6 KNZ71613.1 - 5.5e-47 160.3 0.0 6.9e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ71613.1 - 5.3e-36 123.9 0.1 6.2e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ71613.1 - 1.5e-09 38.1 0.0 2.1e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.21 KNZ71613.1 - 0.01 15.3 0.1 0.024 14.1 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Zn_ribbon_17 PF17120.5 KNZ71614.1 - 4.1e-05 23.1 6.5 4.1e-05 23.1 6.5 3.0 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 KNZ71614.1 - 0.0048 17.0 1.6 0.018 15.1 1.6 2.0 1 0 0 1 1 1 1 KIAA1045 RING finger WD40 PF00400.32 KNZ71614.1 - 0.0065 17.3 17.6 0.19 12.7 0.7 5.9 5 2 0 5 5 5 2 WD domain, G-beta repeat GMC_oxred_N PF00732.19 KNZ71615.1 - 4.3e-56 190.5 0.0 6e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ71615.1 - 2.6e-34 118.8 0.2 4.1e-34 118.2 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ71615.1 - 0.00024 21.2 0.3 0.00081 19.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ71615.1 - 0.00074 18.7 0.3 0.0018 17.4 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ71615.1 - 0.0016 17.6 0.7 0.17 11.0 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KNZ71615.1 - 0.0052 16.1 0.1 0.014 14.6 0.1 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KNZ71615.1 - 0.0083 15.7 2.4 0.0091 15.6 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ71615.1 - 0.021 14.0 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KNZ71615.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Phage-tail_1 PF09097.10 KNZ71615.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 TrkA_N PF02254.18 KNZ71615.1 - 0.14 12.4 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KNZ71615.1 - 0.18 10.5 0.2 11 4.5 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein Internalin_N PF12354.8 KNZ71615.1 - 0.37 10.9 1.2 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Pkinase PF00069.25 KNZ71616.1 - 4.5e-69 232.8 0.0 2.5e-67 227.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71616.1 - 8e-37 126.9 0.0 6.4e-33 114.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ71616.1 - 1.3e-05 24.2 0.3 2.2e-05 23.4 0.3 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KNZ71616.1 - 4.3e-05 23.0 0.0 9.4e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ71616.1 - 0.013 14.9 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 KNZ71616.1 - 0.027 14.0 0.5 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL GMC_oxred_N PF00732.19 KNZ71618.1 - 7.6e-48 163.4 0.1 3.2e-47 161.3 0.1 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ71618.1 - 5.8e-34 117.7 0.2 8.9e-34 117.1 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ71618.1 - 6.8e-05 23.0 0.5 0.00019 21.6 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ71618.1 - 0.00028 20.6 0.5 0.00066 19.4 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ71618.1 - 0.00036 19.7 1.0 0.012 14.7 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 KNZ71618.1 - 0.00046 19.3 0.1 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KNZ71618.1 - 0.0056 16.0 0.0 0.1 11.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KNZ71618.1 - 0.015 14.6 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KNZ71618.1 - 0.03 13.5 0.1 0.068 12.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KNZ71618.1 - 0.085 12.1 0.0 3.7 6.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UCR_TM PF02921.14 KNZ71618.1 - 0.086 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region Phage-tail_1 PF09097.10 KNZ71618.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 DUF2583 PF10762.9 KNZ71620.1 - 0.038 14.4 2.2 0.16 12.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) p450 PF00067.22 KNZ71621.1 - 1.4e-63 215.3 0.0 1.8e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asp_protease_2 PF13650.6 KNZ71623.1 - 2.8e-05 24.7 0.0 0.033 14.8 0.0 2.3 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KNZ71623.1 - 0.00028 21.4 0.0 0.11 13.1 0.0 2.2 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KNZ71623.1 - 0.081 12.7 0.0 7.4 6.3 0.0 2.4 2 1 0 2 2 2 0 Retroviral aspartyl protease YqjK PF13997.6 KNZ71624.1 - 0.59 10.4 6.0 0.64 10.3 0.1 3.4 3 1 1 4 4 4 0 YqjK-like protein Zn_clus PF00172.18 KNZ71624.1 - 2.4 8.4 8.7 11 6.2 9.1 1.9 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MRC1 PF09444.10 KNZ71626.1 - 7.5e-20 71.9 13.6 7.5e-20 71.9 13.6 5.7 8 0 0 8 8 8 2 MRC1-like domain Yos1 PF08571.10 KNZ71627.1 - 1.7 9.0 3.3 12 6.3 0.6 2.6 1 1 2 3 3 3 0 Yos1-like RhoGAP PF00620.27 KNZ71628.1 - 1.2e-40 138.8 0.0 2.1e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KNZ71628.1 - 3e-15 56.6 0.0 6.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.24 KNZ71628.1 - 2.1e-06 27.7 0.0 5.6e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 KNZ71628.1 - 0.022 15.0 0.2 0.16 12.2 0.0 2.4 3 0 0 3 3 3 0 Pleckstrin homology domain SHR3_chaperone PF08229.11 KNZ71629.1 - 3.4e-45 153.3 2.9 1.2e-25 89.6 0.3 2.0 2 0 0 2 2 2 2 ER membrane protein SH3 LSM PF01423.22 KNZ71631.1 - 4.4e-16 58.3 0.0 5.6e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain NMO PF03060.15 KNZ71632.1 - 3.1e-37 128.7 0.8 7.2e-27 94.6 0.1 2.0 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KNZ71632.1 - 1.9e-05 23.9 0.0 0.00072 18.6 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KNZ71632.1 - 0.00016 20.8 0.2 0.00026 20.1 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KNZ71632.1 - 0.0018 17.8 0.1 1 8.7 0.1 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein CPSase_L_D2 PF02786.17 KNZ71633.1 - 2e-80 269.2 0.1 4e-80 268.3 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 KNZ71633.1 - 1e-67 227.8 0.0 2e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 KNZ71633.1 - 1.1e-40 138.5 0.1 2.3e-40 137.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KNZ71633.1 - 2.6e-30 104.7 0.0 9.1e-30 102.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 KNZ71633.1 - 2.2e-27 96.3 0.0 4.6e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KNZ71633.1 - 8.1e-19 67.2 4.3 1.3e-17 63.4 3.8 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KNZ71633.1 - 8.4e-13 47.9 2.3 1.1e-06 28.4 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 KNZ71633.1 - 3e-10 40.0 0.0 6.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KNZ71633.1 - 1.3e-07 31.3 0.0 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 KNZ71633.1 - 6.7e-06 25.5 0.6 0.0014 17.8 0.0 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KNZ71633.1 - 1.1e-05 25.5 0.0 4.6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 KNZ71633.1 - 1.2e-05 25.9 1.0 0.27 12.0 0.3 2.8 2 0 0 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 KNZ71633.1 - 0.00015 21.6 1.4 0.0038 17.1 0.3 3.2 3 1 0 3 3 3 1 Glycine cleavage H-protein ATP-grasp_4 PF13535.6 KNZ71633.1 - 0.00023 20.8 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.11 KNZ71633.1 - 0.0045 16.4 0.3 0.011 15.2 0.3 1.6 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GARS_A PF01071.19 KNZ71633.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 KNZ71633.1 - 0.0073 16.3 0.3 0.28 11.1 0.3 2.8 2 1 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 KNZ71633.1 - 0.014 15.3 0.6 0.042 13.8 0.6 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain PNPase PF03726.14 KNZ71633.1 - 0.089 13.3 0.2 0.28 11.7 0.1 1.9 2 0 0 2 2 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ATPgrasp_ST PF14397.6 KNZ71633.1 - 0.097 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp PTS_EIIA_1 PF00358.20 KNZ71633.1 - 0.13 12.0 0.1 1.1 9.0 0.0 2.4 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 EamA PF00892.20 KNZ71634.1 - 0.0001 22.5 8.5 0.0001 22.5 8.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.20 KNZ71634.1 - 0.005 15.9 1.6 0.005 15.9 1.6 2.3 1 1 0 2 2 2 1 Phosphate transporter family PQ-loop PF04193.14 KNZ71635.1 - 3.5e-16 58.7 5.1 9.9e-13 47.7 1.8 2.7 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KNZ71635.1 - 0.0033 18.3 4.7 0.0069 17.2 4.5 1.7 1 1 0 1 1 1 1 ER lumen protein retaining receptor Ferlin_C PF16165.5 KNZ71635.1 - 0.39 10.7 3.4 1.3 9.0 0.0 2.2 1 1 1 2 2 2 0 Ferlin C-terminus DUF1771 PF08590.10 KNZ71636.1 - 3e-15 56.3 8.0 5.3e-15 55.5 8.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Torus PF16131.5 KNZ71636.1 - 3.5e-08 34.1 2.8 1.8e-05 25.4 0.1 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH PF00642.24 KNZ71636.1 - 3.6e-07 29.9 7.6 0.0011 18.9 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNZ71636.1 - 1e-06 28.5 9.8 0.00023 21.1 1.5 3.0 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KNZ71636.1 - 6.1e-05 23.3 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 Smr domain zf-CCCH_2 PF14608.6 KNZ71636.1 - 0.00029 21.2 7.0 0.043 14.3 1.4 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KNZ71636.1 - 0.0014 18.4 15.0 0.33 10.8 2.1 3.4 2 2 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KNZ71636.1 - 0.0017 18.5 4.5 0.026 14.7 4.5 2.1 1 1 0 1 1 1 1 Zinc-finger containing family zf-C3H1 PF10650.9 KNZ71636.1 - 0.0039 16.9 4.7 0.061 13.1 0.9 2.5 2 0 0 2 2 2 1 Putative zinc-finger domain HBS1_N PF08938.10 KNZ71636.1 - 0.0064 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 HBS1 N-terminus Pkinase_fungal PF17667.1 KNZ71637.1 - 0.15 10.8 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase AAA_12 PF13087.6 KNZ71638.1 - 5e-35 120.9 0.1 1.3e-34 119.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ71638.1 - 3.4e-32 111.6 3.4 5e-09 36.7 0.0 7.1 6 2 1 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KNZ71638.1 - 4.4e-28 98.8 8.1 1.7e-18 67.4 0.0 6.6 6 1 0 6 6 6 2 AAA domain AAA_19 PF13245.6 KNZ71638.1 - 2e-16 60.6 0.0 8.7e-06 26.1 0.0 5.8 5 2 0 5 5 4 4 AAA domain AAA_30 PF13604.6 KNZ71638.1 - 7.6e-16 58.4 1.3 0.0019 17.9 0.0 6.3 6 0 0 6 6 5 4 AAA domain AAA_5 PF07728.14 KNZ71638.1 - 2.3e-12 47.1 0.5 0.14 12.1 0.1 5.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_6 PF17866.1 KNZ71638.1 - 7.8e-11 42.0 0.0 3e-09 36.9 0.1 3.2 2 0 0 2 2 2 1 AAA lid domain Mg_chelatase PF01078.21 KNZ71638.1 - 9e-11 41.5 0.3 0.1 12.0 0.0 4.7 4 0 0 4 4 4 4 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KNZ71638.1 - 1.3e-09 38.1 1.0 0.66 9.7 0.0 4.9 5 0 0 5 5 4 3 IstB-like ATP binding protein AAA_22 PF13401.6 KNZ71638.1 - 1.5e-09 38.2 5.6 0.26 11.5 0.1 6.8 6 2 0 6 6 6 2 AAA domain AAA_16 PF13191.6 KNZ71638.1 - 9e-09 35.9 6.7 0.14 12.6 0.0 5.9 5 0 0 5 5 4 2 AAA ATPase domain RuvB_N PF05496.12 KNZ71638.1 - 1.3e-07 31.5 0.3 0.29 10.9 0.0 4.5 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KNZ71638.1 - 1.3e-07 32.2 7.0 0.29 11.7 0.0 5.6 5 0 0 5 5 4 2 AAA domain RNA_helicase PF00910.22 KNZ71638.1 - 3.1e-06 27.5 0.4 7.7 7.0 0.0 5.3 5 0 0 5 5 5 0 RNA helicase AAA_24 PF13479.6 KNZ71638.1 - 3.9e-06 26.7 7.9 1.5 8.5 0.0 5.4 5 1 0 5 5 5 3 AAA domain DUF2075 PF09848.9 KNZ71638.1 - 7.7e-06 25.4 6.0 0.011 15.0 0.0 6.0 6 1 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KNZ71638.1 - 1e-05 25.1 1.1 8 5.9 0.0 5.2 5 0 0 5 5 5 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KNZ71638.1 - 1.1e-05 25.3 1.9 0.047 13.4 0.0 5.4 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 KNZ71638.1 - 1.3e-05 24.9 0.3 8 6.1 0.0 5.0 5 0 0 5 5 5 0 Sigma-54 interaction domain AAA_33 PF13671.6 KNZ71638.1 - 3.1e-05 24.2 13.3 0.17 12.0 0.0 5.1 5 0 0 5 5 4 3 AAA domain PhoH PF02562.16 KNZ71638.1 - 9.4e-05 22.0 0.5 6.5 6.1 0.0 4.6 4 0 0 4 4 4 0 PhoH-like protein AAA_25 PF13481.6 KNZ71638.1 - 0.00023 20.8 5.0 4.5 6.8 0.0 5.4 6 0 0 6 6 5 1 AAA domain Torsin PF06309.11 KNZ71638.1 - 0.00035 20.7 0.1 2.2 8.4 0.0 4.1 4 0 0 4 4 4 1 Torsin AAA_29 PF13555.6 KNZ71638.1 - 0.0017 18.1 2.3 21 5.0 0.0 4.8 5 0 0 5 5 4 0 P-loop containing region of AAA domain TsaE PF02367.17 KNZ71638.1 - 0.0025 17.8 0.5 0.75 9.8 0.0 3.6 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 KNZ71638.1 - 0.011 15.8 5.1 12 6.0 0.0 4.7 5 0 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF815 PF05673.13 KNZ71638.1 - 0.019 14.2 0.7 2.2 7.4 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF815) MCM PF00493.23 KNZ71638.1 - 0.03 13.4 0.1 0.63 9.1 0.0 2.8 3 0 0 3 3 3 0 MCM P-loop domain NACHT PF05729.12 KNZ71638.1 - 0.033 14.1 4.3 39 4.1 0.0 5.2 5 0 0 5 5 5 0 NACHT domain NTPase_1 PF03266.15 KNZ71638.1 - 0.05 13.5 4.2 9.5 6.1 0.0 4.2 4 0 0 4 4 4 0 NTPase AAA_17 PF13207.6 KNZ71638.1 - 0.39 11.1 0.0 0.39 11.1 0.0 5.0 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.22 KNZ71638.1 - 0.5 10.0 2.4 10 5.7 0.0 3.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KNZ71638.1 - 0.54 9.4 2.0 28 3.8 0.0 3.7 4 0 0 4 4 4 0 NB-ARC domain AAA_28 PF13521.6 KNZ71638.1 - 0.56 10.4 0.0 0.56 10.4 0.0 5.8 7 0 0 7 7 4 0 AAA domain ATPase PF06745.13 KNZ71638.1 - 2.3 7.5 10.0 15 4.8 0.1 4.8 5 0 0 5 5 4 0 KaiC RVP_2 PF08284.11 KNZ71639.1 - 0.071 12.9 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease CNTF PF01110.17 KNZ71641.1 - 0.084 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor gag-asp_proteas PF13975.6 KNZ71646.1 - 4.5e-05 23.9 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ71646.1 - 0.0026 18.4 0.0 0.0061 17.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease rve PF00665.26 KNZ71647.1 - 0.1 12.8 0.0 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain Retrotrans_gag PF03732.17 KNZ71648.1 - 0.022 15.0 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein DUF4939 PF16297.5 KNZ71648.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4939) APH PF01636.23 KNZ71651.1 - 2.2e-06 27.8 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ71651.1 - 0.0073 15.7 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 KNZ71651.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase MFS_1 PF07690.16 KNZ71653.1 - 5.2e-35 121.0 60.7 3.6e-33 114.9 60.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF443 PF04276.12 KNZ71653.1 - 0.089 12.6 1.5 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF443) ketoacyl-synt PF00109.26 KNZ71654.1 - 3.5e-18 66.1 0.0 7.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Glyco_hydro_35 PF01301.19 KNZ71656.1 - 1e-72 245.5 0.0 1.5e-72 244.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KNZ71656.1 - 6.5e-58 194.3 2.0 1.1e-29 103.3 0.1 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KNZ71656.1 - 2.1e-34 118.9 0.8 3.8e-34 118.1 0.8 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KNZ71656.1 - 2.2e-20 72.0 0.1 7.1e-20 70.4 0.1 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KNZ71656.1 - 0.14 11.5 0.1 2.5 7.4 0.1 2.2 1 1 0 1 1 1 0 Beta-galactosidase COX4 PF02936.14 KNZ71657.1 - 3.2e-27 95.2 0.1 6.1e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV POT1PC PF16686.5 KNZ71663.1 - 0.017 15.0 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein DUF3716 PF12511.8 KNZ71664.1 - 0.07 13.2 2.2 0.17 12.0 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF2956 PF11169.8 KNZ71664.1 - 0.1 12.8 1.1 0.46 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RRT14 PF17075.5 KNZ71666.1 - 0.25 11.5 0.1 0.25 11.5 0.1 3.2 3 0 0 3 3 3 0 Regular of rDNA transcription protein 14 Cation_efflux PF01545.21 KNZ71667.1 - 1.2e-50 172.0 15.4 2.7e-50 170.9 15.4 1.5 1 1 0 1 1 1 1 Cation efflux family Alginate_lyase PF05426.12 KNZ71669.1 - 1.3e-38 133.1 3.6 3.6e-38 131.7 3.6 1.7 1 1 0 1 1 1 1 Alginate lyase CCB2_CCB4 PF11152.8 KNZ71670.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Globin PF00042.22 KNZ71670.1 - 0.1 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Globin Pkinase PF00069.25 KNZ71671.1 - 3e-05 23.5 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71671.1 - 0.0076 15.6 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_1 PF00560.33 KNZ71672.1 - 0.016 15.7 1.9 36 5.5 0.1 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 KNZ71673.1 - 3e-05 23.5 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71673.1 - 0.0076 15.6 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNA_Me_trans PF04252.13 KNZ71677.1 - 1e-75 253.8 0.0 1.1e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Annexin PF00191.20 KNZ71678.1 - 6.6e-51 170.2 0.3 4.1e-16 58.8 0.0 4.3 4 0 0 4 4 4 4 Annexin DUF4462 PF14692.6 KNZ71678.1 - 0.18 11.3 0.4 1.1 8.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) F-box-like PF12937.7 KNZ71679.1 - 6.1e-07 29.2 0.6 2.3e-06 27.4 0.6 2.1 1 0 0 1 1 1 1 F-box-like Glyco_hydro_5_C PF18564.1 KNZ71680.1 - 1.5e-24 86.3 0.0 2.8e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KNZ71680.1 - 7.2e-12 45.3 0.0 7.4e-07 28.9 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) COesterase PF00135.28 KNZ71681.1 - 4.1e-89 299.8 0.0 5e-89 299.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ71681.1 - 1.1e-08 35.2 0.0 3.3e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ71681.1 - 0.12 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 KNZ71683.1 - 1.4e-83 281.7 0.0 1.7e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase 2OG-FeII_Oxy PF03171.20 KNZ71685.1 - 9.8e-14 51.7 0.0 1.8e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KNZ71685.1 - 3e-08 34.4 0.0 1e-07 32.7 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal ABC_membrane PF00664.23 KNZ71686.1 - 1.4e-55 188.9 34.4 7.5e-32 111.1 13.9 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ71686.1 - 8e-41 139.8 0.0 1.7e-25 90.2 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ71686.1 - 5.2e-09 35.9 5.8 0.13 11.7 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KNZ71686.1 - 6.8e-08 32.3 3.1 0.018 14.6 2.8 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 KNZ71686.1 - 1e-06 29.2 2.9 0.0093 16.4 0.4 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.29 KNZ71686.1 - 1.6e-06 28.5 0.1 0.13 12.7 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KNZ71686.1 - 6.1e-06 25.9 0.3 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KNZ71686.1 - 4.8e-05 24.0 6.9 0.00044 20.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KNZ71686.1 - 5.2e-05 23.2 5.2 0.024 14.5 0.1 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 KNZ71686.1 - 7e-05 22.6 0.9 0.94 9.2 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 KNZ71686.1 - 7.5e-05 23.0 3.9 0.43 10.8 1.8 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KNZ71686.1 - 0.00023 21.2 0.2 0.36 10.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 KNZ71686.1 - 0.00042 20.5 0.7 0.0055 16.8 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 KNZ71686.1 - 0.0012 18.8 0.1 0.93 9.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KNZ71686.1 - 0.0014 18.1 0.0 0.77 9.2 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 KNZ71686.1 - 0.0015 18.5 1.1 3.6 7.6 0.0 3.9 3 1 1 4 4 4 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KNZ71686.1 - 0.0024 17.0 1.5 0.84 8.6 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein NACHT PF05729.12 KNZ71686.1 - 0.0048 16.8 3.5 9.5 6.1 0.1 3.4 3 0 0 3 3 3 0 NACHT domain Adeno_IVa2 PF02456.15 KNZ71686.1 - 0.0077 15.1 0.1 0.077 11.8 0.0 2.1 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_18 PF13238.6 KNZ71686.1 - 0.014 15.9 0.1 5.2 7.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 KNZ71686.1 - 0.018 15.0 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KNZ71686.1 - 0.024 14.8 0.0 7.5 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KNZ71686.1 - 0.028 14.8 0.0 9.7 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 KNZ71686.1 - 0.037 14.1 0.4 16 5.5 0.2 2.9 2 0 0 2 2 2 0 Dynamin family Pox_A32 PF04665.12 KNZ71686.1 - 0.048 13.1 0.9 0.45 9.9 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein ResIII PF04851.15 KNZ71686.1 - 0.048 13.7 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_15 PF13175.6 KNZ71686.1 - 0.055 13.2 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KNZ71686.1 - 0.062 12.6 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.6 KNZ71686.1 - 0.079 12.7 0.2 0.25 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 KNZ71686.1 - 0.082 12.6 0.9 2.7 7.7 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 KNZ71686.1 - 0.099 11.8 2.1 2.6 7.2 0.1 2.8 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KNZ71686.1 - 0.11 12.2 1.1 3.3 7.4 0.2 2.5 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KNZ71686.1 - 2.4 7.7 6.0 37 3.8 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Glyco_hydro_1 PF00232.18 KNZ71687.1 - 1.8e-140 468.3 1.2 6.6e-113 377.5 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 1 adh_short_C2 PF13561.6 KNZ71688.1 - 5.9e-52 176.6 2.4 6.3e-51 173.2 2.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ71688.1 - 8e-43 146.2 0.6 3.4e-41 140.9 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ71688.1 - 4.3e-09 36.5 0.1 7.2e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 KR domain TRI5 PF06330.11 KNZ71689.1 - 6.1e-29 101.0 1.3 8e-29 100.6 1.3 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) F-box-like PF12937.7 KNZ71690.1 - 0.012 15.5 0.1 0.048 13.6 0.1 2.0 1 0 0 1 1 1 0 F-box-like TRI5 PF06330.11 KNZ71691.1 - 6.5e-22 77.9 0.1 1.8e-21 76.4 0.0 1.5 1 1 0 1 1 1 1 Trichodiene synthase (TRI5) FHA PF00498.26 KNZ71692.1 - 3.4e-06 27.3 0.0 7.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KNZ71692.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain UbiA PF01040.18 KNZ71693.1 - 2.3e-45 154.9 20.8 2.9e-45 154.6 20.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Isy1 PF06246.12 KNZ71694.1 - 1.4e-76 257.4 3.0 1.7e-76 257.2 3.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family N2227 PF07942.12 KNZ71695.1 - 9.8e-87 290.6 0.0 4.8e-58 196.5 0.0 2.1 2 0 0 2 2 2 2 N2227-like protein TPMT PF05724.11 KNZ71695.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) SelP_N PF04592.14 KNZ71695.1 - 3.7 6.9 10.0 5.8 6.3 10.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sugar_tr PF00083.24 KNZ71696.1 - 8.4e-108 361.1 27.1 1e-107 360.9 27.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ71696.1 - 2.1e-27 96.0 26.6 2.1e-27 96.0 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PT-VENN PF04829.13 KNZ71696.1 - 0.94 9.6 2.8 3.8 7.7 2.8 2.2 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif OTT_1508_deam PF14441.6 KNZ71698.1 - 2.8e-10 40.0 0.5 7.2e-10 38.7 0.5 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase PLATZ PF04640.14 KNZ71698.1 - 0.057 14.0 0.1 0.27 11.9 0.1 2.1 1 0 0 1 1 1 0 PLATZ transcription factor Argos PF11581.8 KNZ71698.1 - 0.11 12.5 0.8 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Antagonist of EGFR signalling, Argos COPIIcoated_ERV PF07970.12 KNZ71699.1 - 1.3e-34 120.0 1.2 1.6e-34 119.7 0.3 1.6 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KNZ71699.1 - 6.5e-22 77.7 0.0 1.1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CBM60 PF16841.5 KNZ71700.1 - 0.032 14.6 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Peptidase_M36 PF02128.15 KNZ71701.1 - 9.1e-45 153.4 9.4 3.2e-35 122.0 4.1 2.1 1 1 1 2 2 2 2 Fungalysin metallopeptidase (M36) Pkinase PF00069.25 KNZ71702.1 - 7e-08 32.2 1.7 2e-07 30.7 1.7 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71702.1 - 0.00028 20.3 0.2 0.0011 18.3 0.2 1.7 1 1 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 KNZ71702.1 - 0.0075 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KNZ71702.1 - 0.019 14.9 2.8 0.24 11.3 0.6 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family rve PF00665.26 KNZ71704.1 - 0.00037 20.7 0.0 0.00082 19.5 0.0 1.6 1 1 1 2 2 2 1 Integrase core domain Helitron_like_N PF14214.6 KNZ71706.1 - 0.008 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Integrase_H2C2 PF17921.1 KNZ71707.1 - 7.9e-15 54.7 0.6 1.4e-14 53.9 0.6 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain RT_RNaseH PF17917.1 KNZ71707.1 - 6.6e-11 42.4 0.0 1.7e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ71707.1 - 1.5e-08 34.6 0.0 4.7e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KNZ71707.1 - 0.00012 22.3 0.0 0.00026 21.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain POT1PC PF16686.5 KNZ71707.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Senescence PF06911.12 KNZ71709.1 - 0.018 15.4 0.1 0.022 15.1 0.1 1.3 1 0 0 1 1 1 0 Senescence-associated protein DUF2286 PF10051.9 KNZ71709.1 - 0.061 13.1 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) Sod_Fe_C PF02777.18 KNZ71712.1 - 6.8e-12 45.5 0.1 6.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DAD PF02109.16 KNZ71713.1 - 5.4e-47 158.6 1.8 6.1e-47 158.4 1.8 1.0 1 0 0 1 1 1 1 DAD family Cyt_b-c1_8 PF10890.8 KNZ71713.1 - 0.069 13.6 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 SSP160 PF06933.11 KNZ71713.1 - 0.11 10.6 0.0 0.13 10.5 0.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1748 PF08520.10 KNZ71714.1 - 1.5e-19 69.6 0.0 1.6e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF2838 PF10998.8 KNZ71715.1 - 9.6e-44 148.2 10.8 2.1e-43 147.1 10.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Hexokinase_2 PF03727.16 KNZ71716.1 - 4.5e-75 252.2 0.0 5.9e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KNZ71716.1 - 1.1e-69 234.3 0.0 1.5e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase UPF0270 PF06794.12 KNZ71716.1 - 0.0055 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0270) Gly-zipper_Omp PF13488.6 KNZ71716.1 - 0.76 9.8 4.5 1.4 9.0 1.4 2.5 2 0 0 2 2 2 0 Glycine zipper Integrase_H2C2 PF17921.1 KNZ71718.1 - 4.3e-15 55.5 0.6 8.3e-15 54.6 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KNZ71718.1 - 0.00099 19.3 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain POT1PC PF16686.5 KNZ71718.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein AAA_22 PF13401.6 KNZ71719.1 - 0.092 13.0 0.1 19 5.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 KNZ71721.1 - 8.2e-07 29.6 0.1 0.028 15.3 0.0 4.1 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ71721.1 - 1.2e-05 25.6 0.0 3.1 8.1 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KNZ71721.1 - 0.00024 21.5 0.3 2.7 8.6 0.0 4.8 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 KNZ71721.1 - 0.0037 16.9 1.2 0.11 12.0 0.0 3.2 3 1 1 4 4 4 2 PQQ-like domain BBS2_Mid PF14783.6 KNZ71721.1 - 0.0054 16.8 0.3 6.6 6.8 0.0 3.6 3 2 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KNZ71721.1 - 0.015 15.2 0.1 1.2 9.2 0.0 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat BBS1 PF14779.6 KNZ71721.1 - 0.054 12.9 0.5 4.8 6.5 0.0 3.2 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 1 Asp_protease_2 PF13650.6 KNZ71724.1 - 0.0014 19.2 0.0 0.0017 19.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KNZ71724.1 - 0.013 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KNZ71724.1 - 0.014 16.0 0.0 0.017 15.7 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2205 PF10224.9 KNZ71725.1 - 0.13 12.3 9.3 0.061 13.3 2.3 3.2 4 0 0 4 4 4 0 Short coiled-coil protein Spc42p PF11544.8 KNZ71725.1 - 0.13 12.3 6.4 0.095 12.7 0.6 2.8 2 0 0 2 2 2 0 Spindle pole body component Spc42p DivIC PF04977.15 KNZ71725.1 - 0.21 11.4 9.0 0.058 13.2 1.4 2.4 2 0 0 2 2 2 0 Septum formation initiator CSN5_C PF18323.1 KNZ71725.1 - 0.21 12.5 6.5 3.9 8.4 0.3 2.6 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF1307 PF06998.11 KNZ71725.1 - 0.44 10.6 10.9 0.11 12.6 6.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1307) Med9 PF07544.13 KNZ71725.1 - 0.47 10.6 7.0 7.1 6.8 0.6 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SKA1 PF07160.12 KNZ71725.1 - 0.54 10.1 10.4 0.071 12.9 2.3 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 TSNAXIP1_N PF15739.5 KNZ71725.1 - 0.64 10.4 8.2 0.46 10.9 3.1 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus SlyX PF04102.12 KNZ71725.1 - 0.76 10.4 6.9 0.61 10.7 1.1 2.6 2 0 0 2 2 2 0 SlyX Phage_HK97_TLTM PF06120.11 KNZ71725.1 - 0.91 8.7 12.8 0.028 13.6 5.0 2.0 2 0 0 2 2 2 0 Tail length tape measure protein DHR10 PF18595.1 KNZ71725.1 - 2.4 8.3 14.2 5.3 7.1 3.4 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Mt_ATP-synt_D PF05873.12 KNZ71725.1 - 3.2 7.6 12.4 0.44 10.4 0.2 3.0 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) YabA PF06156.13 KNZ71725.1 - 5.2 7.8 8.8 1.1 9.9 2.9 2.4 2 0 0 2 2 2 0 Initiation control protein YabA FlxA PF14282.6 KNZ71725.1 - 8.5 6.4 16.4 6.4 6.8 3.6 2.5 2 0 0 2 2 2 0 FlxA-like protein CMV_1a PF12467.8 KNZ71727.1 - 0.75 10.1 3.0 0.45 10.8 1.5 1.5 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family NACHT PF05729.12 KNZ71731.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.6 1 1 0 1 1 1 1 NACHT domain Creatininase PF02633.14 KNZ71731.1 - 0.064 12.7 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 Creatinine amidohydrolase Pkinase PF00069.25 KNZ71732.1 - 8.9e-37 126.9 0.0 5.1e-36 124.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71732.1 - 1.3e-15 57.4 0.0 2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ71732.1 - 0.00054 20.0 0.0 0.0033 17.4 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ71732.1 - 0.003 16.7 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 KNZ71732.1 - 0.018 14.0 0.1 0.028 13.4 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KNZ71732.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 KNZ71732.1 - 0.048 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KNZ71732.1 - 0.072 11.9 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EF-hand_1 PF00036.32 KNZ71733.1 - 1.5e-26 89.9 16.6 2.4e-09 36.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KNZ71733.1 - 2.3e-26 92.0 14.1 3.1e-13 50.0 4.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KNZ71733.1 - 7.9e-23 78.4 12.0 2e-08 33.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 KNZ71733.1 - 5.8e-15 54.9 15.1 6e-09 35.6 1.6 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 KNZ71733.1 - 1.6e-12 47.6 2.0 4.5e-06 26.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 KNZ71733.1 - 8.1e-11 40.9 6.3 0.0011 18.3 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 KNZ71733.1 - 2.2e-08 34.0 6.7 0.00054 19.9 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 KNZ71733.1 - 0.00034 20.6 2.7 0.067 13.1 0.0 3.4 2 1 1 3 3 3 1 Caleosin related protein DUF1636 PF07845.11 KNZ71733.1 - 0.00085 19.7 0.0 1.2 9.6 0.0 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1636) SPARC_Ca_bdg PF10591.9 KNZ71733.1 - 0.01 16.1 3.3 1 9.7 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 KNZ71733.1 - 0.017 15.4 2.6 0.31 11.4 0.3 2.4 2 1 0 2 2 2 0 EF-hand domain EF-hand_11 PF08976.11 KNZ71733.1 - 0.064 14.1 0.5 13 6.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 KNZ71733.1 - 0.1 12.4 0.9 3.5 7.5 0.3 2.4 2 1 0 2 2 2 0 SurA N-terminal domain YolD PF08863.10 KNZ71733.1 - 0.2 11.7 1.3 0.38 10.8 0.1 2.1 3 0 0 3 3 3 0 YolD-like protein zf-C2H2 PF00096.26 KNZ71734.1 - 4.5e-10 39.4 7.5 0.0003 21.1 1.9 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ71734.1 - 0.00035 20.8 3.6 0.00035 20.8 3.6 3.8 4 0 0 4 4 4 1 Zinc-finger double domain TFIIA PF03153.13 KNZ71734.1 - 0.0027 17.8 14.9 0.0027 17.8 14.9 1.8 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.6 KNZ71734.1 - 0.0042 17.8 19.7 0.013 16.3 1.3 4.8 5 0 0 5 5 5 2 C2H2-type zinc finger Na_trans_assoc PF06512.13 KNZ71734.1 - 0.05 13.9 0.9 0.096 13.0 0.9 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated zf-H2C2_5 PF13909.6 KNZ71734.1 - 0.62 9.9 7.8 3.8 7.4 1.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PBP1_TM PF14812.6 KNZ71734.1 - 1.7 9.1 8.8 2.8 8.4 5.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.26 KNZ71735.1 - 1.1e-06 28.7 17.8 0.001 19.4 4.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ71735.1 - 0.00061 20.1 7.8 0.00061 20.1 7.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ71735.1 - 0.0022 18.7 16.1 0.087 13.7 4.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KNZ71735.1 - 0.013 15.8 2.0 0.031 14.6 2.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon FANCL_C PF11793.8 KNZ71735.1 - 0.056 13.6 2.1 0.1 12.8 2.1 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain FOXP-CC PF16159.5 KNZ71735.1 - 0.068 13.8 7.4 0.27 11.9 0.4 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 KNZ71735.1 - 5.1 7.5 9.3 0.27 11.6 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PAP_assoc PF03828.19 KNZ71738.1 - 1.5e-05 25.1 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KNZ71738.1 - 3.9e-05 23.9 0.0 0.00011 22.4 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain Glucan_synthase PF02364.15 KNZ71742.1 - 0 1321.0 0.0 0 1320.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KNZ71742.1 - 6.4e-43 146.2 0.2 2e-42 144.5 0.2 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 REV PF00424.18 KNZ71743.1 - 0.041 13.9 0.5 0.095 12.7 0.5 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) SpoIIE PF07228.12 KNZ71744.1 - 7.4e-13 48.8 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KNZ71744.1 - 2.7e-06 27.2 0.0 8.8e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.8 KNZ71744.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III PP2C PF00481.21 KNZ71744.1 - 0.079 12.6 0.1 1.7 8.2 0.0 2.3 3 0 0 3 3 3 0 Protein phosphatase 2C Peptidase_M49 PF03571.15 KNZ71745.1 - 4.8e-216 718.4 0.0 5.7e-216 718.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 FAD_binding_3 PF01494.19 KNZ71746.1 - 4.2e-37 128.2 0.0 8.9e-23 81.1 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KNZ71746.1 - 4.3e-06 26.2 0.0 0.061 12.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ71746.1 - 3e-05 23.5 0.0 0.00022 20.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ71746.1 - 0.00034 19.5 0.0 0.37 9.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 KNZ71746.1 - 0.0058 15.7 0.1 0.03 13.4 0.0 2.1 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KNZ71746.1 - 0.014 14.8 0.4 0.16 11.3 0.4 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ71746.1 - 0.014 15.6 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KNZ71746.1 - 0.016 15.2 0.0 0.99 9.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ71746.1 - 0.019 15.5 0.1 9.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ71746.1 - 0.038 13.1 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KNZ71746.1 - 0.038 13.6 0.0 0.44 10.1 0.0 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 KNZ71746.1 - 0.058 12.4 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 KNZ71746.1 - 0.1 11.9 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KNZ71746.1 - 0.12 12.6 0.1 1 9.6 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain TPR_12 PF13424.6 KNZ71747.1 - 2.9e-05 24.3 18.5 0.12 12.7 1.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ71747.1 - 0.0096 15.8 0.2 0.0096 15.8 0.2 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ71747.1 - 0.024 14.7 8.8 1.5 9.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ71747.1 - 0.071 13.0 4.5 10 6.1 0.7 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ71747.1 - 0.077 13.2 3.2 2.6 8.5 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Cellulase PF00150.18 KNZ71748.1 - 8.1e-15 55.0 0.5 2.5e-14 53.4 0.3 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KNZ71748.1 - 1.2e-05 25.1 0.2 0.0041 16.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KNZ71748.1 - 0.00019 20.9 0.5 0.0055 16.1 0.2 2.7 2 1 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 KNZ71748.1 - 0.092 11.8 0.3 0.62 9.1 0.0 2.3 3 0 0 3 3 3 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_1 PF00232.18 KNZ71748.1 - 0.12 10.8 0.2 0.37 9.1 0.2 1.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 1 DEAD_2 PF06733.15 KNZ71749.1 - 1.5e-53 181.1 0.0 2.6e-53 180.2 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 KNZ71749.1 - 2.3e-44 151.4 1.1 3.9e-38 131.1 0.1 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KNZ71749.1 - 1.3e-42 145.8 0.0 2.6e-42 144.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 KNZ71749.1 - 0.00016 21.7 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNZ71749.1 - 0.0069 16.2 0.1 3.1 7.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Peptidase_M41 PF01434.18 KNZ71750.1 - 1.8e-56 191.0 0.0 3.1e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KNZ71750.1 - 2.1e-43 147.9 0.0 9.4e-43 145.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ71750.1 - 2e-09 37.1 0.0 4.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KNZ71750.1 - 9.8e-06 25.6 0.2 0.00012 22.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ71750.1 - 3.3e-05 24.3 3.2 0.002 18.5 0.2 3.0 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KNZ71750.1 - 0.00012 21.8 0.0 0.00036 20.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KNZ71750.1 - 0.00015 21.1 0.0 0.00037 19.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 KNZ71750.1 - 0.00081 19.7 0.3 0.03 14.6 0.4 2.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KNZ71750.1 - 0.005 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 KNZ71750.1 - 0.013 15.1 1.1 0.93 9.0 0.5 2.8 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 KNZ71750.1 - 0.015 15.8 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KNZ71750.1 - 0.017 14.5 0.3 0.037 13.4 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KNZ71750.1 - 0.019 15.2 0.7 0.043 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KNZ71750.1 - 0.038 14.0 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KNZ71750.1 - 0.043 13.0 0.0 0.096 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 KNZ71750.1 - 0.045 13.9 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KNZ71750.1 - 0.046 13.4 0.3 0.24 11.1 0.0 2.3 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KNZ71750.1 - 0.047 13.2 0.1 0.3 10.6 0.1 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 KNZ71750.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 KNZ71750.1 - 0.076 12.9 0.1 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 KNZ71750.1 - 0.087 12.2 0.4 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 KNZ71750.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KNZ71750.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Amidohydro_2 PF04909.14 KNZ71750.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase RNA_helicase PF00910.22 KNZ71750.1 - 0.18 12.2 0.1 1 9.8 0.0 2.3 2 1 0 2 2 1 0 RNA helicase GCIP PF13324.6 KNZ71751.1 - 2.3e-43 148.7 0.2 4.2e-43 147.8 0.1 1.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Exo70 PF03081.15 KNZ71751.1 - 0.0051 15.9 0.3 1.6 7.7 0.1 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit FBPase PF00316.20 KNZ71753.1 - 2.6e-74 248.8 0.2 3.2e-74 248.5 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 KNZ71753.1 - 0.00022 20.8 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family zf-H2C2_2 PF13465.6 KNZ71754.1 - 2.8e-22 78.1 22.4 1.4e-06 28.4 2.3 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 KNZ71754.1 - 1.4e-21 75.7 28.7 2.2e-05 24.6 3.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ71754.1 - 3.4e-11 43.0 24.3 0.021 15.6 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNZ71754.1 - 9.5e-06 25.8 1.6 2 8.8 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ71754.1 - 2.7e-05 24.4 4.6 0.2 12.1 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KNZ71754.1 - 0.0036 17.0 13.1 0.047 13.4 0.8 4.5 4 0 0 4 4 4 1 C2H2-type zinc-finger domain FOXP-CC PF16159.5 KNZ71754.1 - 0.036 14.7 8.6 0.49 11.1 0.1 3.7 3 1 1 4 4 4 0 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 KNZ71754.1 - 0.083 13.2 8.1 1.6 9.1 0.8 3.0 1 1 1 3 3 3 0 C2H2-type zinc ribbon Minor_capsid_2 PF11114.8 KNZ71754.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Minor capsid protein zf-C2H2_6 PF13912.6 KNZ71754.1 - 0.54 10.3 0.1 0.54 10.3 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-TRAF PF02176.18 KNZ71754.1 - 0.87 10.3 14.7 0.2 12.4 3.4 3.1 1 1 2 3 3 3 0 TRAF-type zinc finger zf-CGNR PF11706.8 KNZ71754.1 - 1.6 8.7 12.8 38 4.3 0.4 4.4 4 0 0 4 4 4 0 CGNR zinc finger Pmp3 PF01679.17 KNZ71755.1 - 7.5e-17 61.3 3.0 1e-16 60.9 3.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PNGaseA PF12222.8 KNZ71756.1 - 5e-129 430.9 2.7 6.8e-129 430.5 2.7 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A BACON PF13004.7 KNZ71756.1 - 0.43 10.6 0.1 0.43 10.6 0.1 2.8 2 1 0 2 2 2 0 Putative binding domain, N-terminal FTHFS PF01268.19 KNZ71757.1 - 1.5e-254 845.4 0.0 2.2e-254 844.8 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KNZ71757.1 - 1.8e-65 219.1 0.1 4.4e-65 217.9 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KNZ71757.1 - 5.3e-35 120.2 0.1 1.2e-34 119.1 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GrpE PF01025.19 KNZ71758.1 - 3.7e-43 147.1 0.4 5.2e-43 146.6 0.4 1.2 1 0 0 1 1 1 1 GrpE HAUS-augmin3 PF14932.6 KNZ71758.1 - 1.2 8.7 9.8 1.9 8.0 0.4 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 4F5 PF04419.14 KNZ71758.1 - 1.5 9.8 11.7 0.95 10.4 2.6 2.7 2 0 0 2 2 2 0 4F5 protein family Uds1 PF15456.6 KNZ71758.1 - 6.6 6.9 9.0 26 5.0 3.3 2.4 1 1 1 2 2 2 0 Up-regulated During Septation tRNA-synt_2d PF01409.20 KNZ71759.1 - 5.3e-27 94.9 0.1 5.7e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 KNZ71759.1 - 5.2e-23 81.3 0.0 1.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF3552 PF12072.8 KNZ71760.1 - 0.004 16.6 6.5 0.021 14.2 2.8 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) Lzipper-MIP1 PF14389.6 KNZ71760.1 - 0.06 13.6 0.6 1.9 8.8 0.0 2.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1090 PF06476.12 KNZ71760.1 - 0.8 9.8 4.2 10 6.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) DUF948 PF06103.11 KNZ71761.1 - 0.81 10.0 7.8 1.2 9.5 1.5 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Vps5 PF09325.10 KNZ71761.1 - 7.7 6.0 14.2 0.22 11.1 4.7 2.4 2 1 0 2 2 2 0 Vps5 C terminal like Porin_3 PF01459.22 KNZ71762.1 - 2.3e-85 286.3 5.5 2.7e-85 286.1 5.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Glyco_transf_15 PF01793.16 KNZ71763.1 - 1.3e-121 405.8 10.1 1.5e-121 405.6 10.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 KNZ71763.1 - 0.087 13.1 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Glyco_transf_15 PF01793.16 KNZ71764.1 - 3.8e-122 407.6 7.8 4.8e-122 407.3 7.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PI3_PI4_kinase PF00454.27 KNZ71765.1 - 1.1e-33 117.2 0.0 1.2e-32 113.8 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 KNZ71765.1 - 0.0011 18.8 0.0 0.33 10.9 0.0 3.6 3 0 0 3 3 3 1 Yeast phosphatidylinositol-4-OH kinase Pik1 OST3_OST6 PF04756.13 KNZ71766.1 - 2.7e-89 299.4 0.0 3.3e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 KNZ71766.1 - 0.00028 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin 7TMR-DISM_7TM PF07695.11 KNZ71766.1 - 0.47 10.3 8.4 2.3 8.1 8.4 2.0 1 1 0 1 1 1 0 7TM diverse intracellular signalling Sec16_C PF12931.7 KNZ71767.1 - 1.4e-99 333.5 0.0 2e-99 333.1 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KNZ71767.1 - 1.9e-27 96.2 0.7 1e-26 93.8 0.0 2.6 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region RHH_8 PF17723.1 KNZ71767.1 - 0.13 12.4 0.1 0.86 9.8 0.1 2.0 2 0 0 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family PUF PF00806.19 KNZ71768.1 - 2.7e-61 199.9 7.5 7.5e-09 34.8 0.0 9.8 9 1 0 9 9 9 8 Pumilio-family RNA binding repeat CoA_binding_2 PF13380.6 KNZ71768.1 - 0.054 14.0 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 CoA binding domain Kinesin PF00225.23 KNZ71769.1 - 6.8e-113 377.0 0.1 6.8e-113 377.0 0.1 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ71769.1 - 5.1e-28 97.9 0.0 2.1e-27 95.9 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding DUF465 PF04325.13 KNZ71769.1 - 0.00016 21.6 19.5 0.00019 21.4 9.2 3.6 2 1 0 2 2 2 1 Protein of unknown function (DUF465) TFA2_Winged_2 PF18121.1 KNZ71769.1 - 0.043 13.5 1.1 0.48 10.2 1.1 3.0 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 DUF3580 PF12117.8 KNZ71769.1 - 0.092 13.0 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3580) Pro_Al_protease PF02983.14 KNZ71769.1 - 0.19 11.8 1.7 1.1 9.3 1.3 2.7 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Elf1 PF05129.13 KNZ71770.1 - 3e-29 100.9 0.5 3.6e-29 100.6 0.5 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.12 KNZ71770.1 - 0.033 14.7 0.4 0.05 14.1 0.4 1.3 1 0 0 1 1 1 0 CHY zinc finger PHD_4 PF16866.5 KNZ71770.1 - 0.093 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 PHD-finger Kinesin PF00225.23 KNZ71771.1 - 4.4e-108 361.1 0.0 8.5e-108 360.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ71771.1 - 1.3e-22 80.4 0.0 3.6e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Microtub_bind PF13931.6 KNZ71771.1 - 0.0048 17.3 0.1 0.0048 17.3 0.1 5.0 4 2 3 7 7 7 1 Kinesin-associated microtubule-binding Spidroin_N PF16763.5 KNZ71771.1 - 0.043 13.8 4.5 0.8 9.7 0.1 3.2 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term Lant_dehydr_C PF14028.6 KNZ71771.1 - 2.8 7.4 12.4 2.5 7.6 0.8 3.6 2 1 0 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term Vps55 PF04133.14 KNZ71772.1 - 1.9e-44 150.4 5.2 2.1e-44 150.2 5.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 TRAPPC9-Trs120 PF08626.11 KNZ71773.1 - 2.5e-200 667.8 0.0 2.5e-198 661.2 0.0 2.0 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 KNZ71773.1 - 0.00052 20.2 0.1 0.016 15.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat DPM2 PF07297.12 KNZ71774.1 - 5e-30 103.6 0.4 5.6e-30 103.5 0.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KNZ71774.1 - 6.2e-06 26.1 0.3 6.6e-06 26.0 0.3 1.1 1 0 0 1 1 1 1 PIG-P Peptidase_M28 PF04389.17 KNZ71774.1 - 0.041 13.6 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 UNC-79 PF14776.6 KNZ71775.1 - 0.0083 14.9 0.0 0.021 13.6 0.0 1.6 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 C1_1 PF00130.22 KNZ71775.1 - 0.086 12.7 2.2 0.18 11.7 2.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KNZ71775.1 - 1.1 9.3 4.4 2.1 8.3 4.4 1.4 1 0 0 1 1 1 0 PHD-finger DUF4211 PF13926.6 KNZ71776.1 - 2.2e-33 115.3 0.0 1.1e-32 113.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Peptidase_C14 PF00656.22 KNZ71776.1 - 0.0018 18.2 2.6 0.0044 17.0 0.8 2.2 2 0 0 2 2 2 1 Caspase domain TFIID-18kDa PF02269.16 KNZ71777.1 - 1.3e-16 60.3 2.4 1.6e-14 53.7 2.4 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit RRM_1 PF00076.22 KNZ71778.1 - 6.2e-16 58.0 0.1 1.8e-15 56.5 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ71778.1 - 1e-09 38.4 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 KNZ71778.1 - 0.0005 20.0 0.0 0.00076 19.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Pkinase PF00069.25 KNZ71779.1 - 4.1e-12 46.0 0.1 7.4e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71779.1 - 1.9e-05 24.1 0.0 0.00024 20.5 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ71779.1 - 0.03 13.1 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2040 PF09745.9 KNZ71780.1 - 2.2e-35 121.3 24.0 2.2e-35 121.3 24.0 3.5 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) RNase_PH PF01138.21 KNZ71781.1 - 3.7e-31 108.3 0.0 5.1e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KNZ71781.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 AA_permease_2 PF13520.6 KNZ71782.1 - 3.8e-58 197.3 39.7 5e-58 196.9 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ71782.1 - 6.6e-22 77.8 34.8 1e-21 77.1 34.8 1.2 1 0 0 1 1 1 1 Amino acid permease HMA PF00403.26 KNZ71783.1 - 2.4e-08 34.3 0.1 3.4e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain TRM PF02005.16 KNZ71784.1 - 2.7e-121 405.3 0.0 3.4e-121 405.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KNZ71784.1 - 0.0034 17.1 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Spermine_synth PF01564.17 KNZ71784.1 - 0.025 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain Pkinase PF00069.25 KNZ71785.1 - 1.2e-68 231.3 0.0 1.6e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71785.1 - 1.2e-47 162.4 0.0 1.7e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 KNZ71785.1 - 4.2e-16 59.1 0.0 7.5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ras_bdg_2 PF14847.6 KNZ71785.1 - 1.9e-14 53.8 0.0 4e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 KNZ71785.1 - 4.1e-14 52.4 0.0 7.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 KNZ71785.1 - 3.9e-05 23.1 0.0 0.0042 16.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KNZ71785.1 - 0.00078 18.3 0.0 0.0018 17.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 KNZ71785.1 - 0.0037 17.2 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Alpha-amylase PF00128.24 KNZ71786.1 - 8.6e-22 78.1 0.3 3.8e-17 62.9 0.1 3.1 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.11 KNZ71786.1 - 5.6e-16 59.0 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KNZ71786.1 - 1.3e-07 31.3 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 PRCC PF10253.9 KNZ71787.1 - 1.4e-27 97.9 16.1 1.4e-27 97.9 16.1 3.3 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Histone PF00125.24 KNZ71788.1 - 9.8e-22 77.7 2.4 1.3e-21 77.3 2.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNZ71788.1 - 1.5e-05 25.2 0.1 3.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KNZ71788.1 - 0.0003 21.2 0.0 0.00053 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A IHO1 PF15771.5 KNZ71788.1 - 0.021 13.6 1.1 0.024 13.4 1.1 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 YscO-like PF16789.5 KNZ71788.1 - 0.027 14.5 0.3 0.032 14.3 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein Bt_P21 PF05560.11 KNZ71788.1 - 0.1 12.2 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein PRIMA1 PF16101.5 KNZ71790.1 - 8.4 6.5 8.5 20 5.2 8.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SAP PF02037.27 KNZ71791.1 - 1.2e-10 40.9 0.1 1.9e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 SAP domain DUF2315 PF10231.9 KNZ71792.1 - 6.6e-24 84.4 3.1 2.2e-23 82.7 3.1 1.7 1 1 0 1 1 1 1 Apoptogenic protein 1 Nucleoporin_C PF03177.14 KNZ71793.1 - 5.4e-70 236.8 0.0 6.5e-69 233.2 0.0 2.0 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 KNZ71793.1 - 1.2e-17 63.8 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Histone PF00125.24 KNZ71794.1 - 1.8e-21 76.9 2.2 2.5e-21 76.4 2.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNZ71794.1 - 1.6e-05 25.1 0.1 3.6e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KNZ71794.1 - 0.0003 21.2 0.0 0.00053 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A IHO1 PF15771.5 KNZ71794.1 - 0.026 13.3 0.9 0.03 13.1 0.9 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 YscO-like PF16789.5 KNZ71794.1 - 0.037 14.1 0.3 0.045 13.8 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein Bt_P21 PF05560.11 KNZ71794.1 - 0.096 12.3 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Methyltransf_11 PF08241.12 KNZ71795.1 - 1e-15 58.2 0.0 3e-15 56.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ71795.1 - 1.3e-12 48.3 0.0 3.5e-12 46.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ71795.1 - 5.2e-08 33.5 0.0 1.1e-07 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ71795.1 - 2.4e-07 30.7 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ71795.1 - 5.3e-05 22.7 0.0 8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 KNZ71795.1 - 0.0008 19.1 0.0 0.0018 17.9 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_24 PF13578.6 KNZ71795.1 - 0.00086 20.3 0.1 0.003 18.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ71795.1 - 0.0068 16.2 0.0 0.044 13.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 KNZ71795.1 - 0.097 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 RrnaAD PF00398.20 KNZ71795.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DAGK_cat PF00781.24 KNZ71796.1 - 7.7e-25 86.9 0.0 1.5e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain WD40 PF00400.32 KNZ71796.1 - 0.0014 19.4 8.7 0.083 13.8 0.6 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Swi3 PF07962.12 KNZ71797.1 - 3.3e-29 100.7 0.1 5e-29 100.1 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.12 KNZ71798.1 - 2.2e-50 171.2 0.0 7.5e-49 166.2 0.0 2.2 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 KNZ71798.1 - 2.2e-05 25.1 0.0 0.24 12.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ71798.1 - 0.00035 20.4 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ71798.1 - 0.0014 19.2 0.0 1.3 9.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ71798.1 - 0.014 16.1 0.0 5.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 KNZ71798.1 - 0.07 12.4 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain ADK PF00406.22 KNZ71799.1 - 3e-46 157.2 0.0 4.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KNZ71799.1 - 3.1e-20 73.0 0.0 6e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KNZ71799.1 - 1.4e-13 50.6 0.0 2.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KNZ71799.1 - 3.8e-08 34.0 0.0 9.6e-08 32.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNZ71799.1 - 0.00076 19.7 0.2 0.0019 18.3 0.0 1.9 2 2 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 KNZ71799.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Epimerase PF01370.21 KNZ71801.1 - 3.4e-09 36.5 0.0 1e-07 31.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ71801.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KNZ71801.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 KNZ71801.1 - 0.0039 16.3 0.0 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KNZ71801.1 - 0.0077 15.4 0.1 2 7.5 0.0 2.7 3 0 0 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KNZ71801.1 - 0.0084 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KNZ71801.1 - 0.028 13.5 0.0 0.089 11.9 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain DPBB_1 PF03330.18 KNZ71802.1 - 2.2e-09 37.5 0.2 6.8e-09 35.9 0.2 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KNZ71802.1 - 1.3e-05 25.0 0.3 2.5e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Barwin family PRCC PF10253.9 KNZ71802.1 - 0.15 12.8 1.9 0.26 12.0 1.9 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Stm1_N PF09598.10 KNZ71802.1 - 9.5 7.1 10.3 92 4.0 10.3 2.2 1 1 0 1 1 1 0 Stm1 SCAMP PF04144.13 KNZ71803.1 - 2e-51 174.7 11.5 2.5e-51 174.4 11.5 1.1 1 0 0 1 1 1 1 SCAMP family Ycf9 PF01737.17 KNZ71803.1 - 0.78 9.7 6.1 3.6 7.5 0.1 2.8 3 0 0 3 3 3 0 YCF9 RRM_1 PF00076.22 KNZ71804.1 - 1.3e-82 271.6 6.6 2.3e-22 78.6 0.5 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KNZ71804.1 - 4.7e-26 90.7 0.7 1.8e-25 88.9 0.6 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 KNZ71804.1 - 7.4e-06 26.0 1.2 1.3 9.2 0.0 4.8 4 3 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 KNZ71804.1 - 9.5e-06 25.6 11.1 0.027 14.5 4.2 3.9 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 KNZ71804.1 - 4.3e-05 23.4 0.6 4.7 7.3 0.0 4.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 KNZ71804.1 - 0.00078 19.3 0.1 0.52 10.2 0.0 3.0 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KNZ71804.1 - 0.002 18.2 0.5 2.7 8.1 0.1 3.4 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.11 KNZ71804.1 - 0.012 15.3 2.6 12 5.6 0.4 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.8 KNZ71804.1 - 0.06 13.9 7.8 0.24 11.9 1.9 2.9 3 0 0 3 3 3 0 Heat induced stress protein YflT IGPD PF00475.18 KNZ71804.1 - 0.077 13.3 0.3 12 6.2 0.0 2.3 1 1 1 2 2 2 0 Imidazoleglycerol-phosphate dehydratase PNPase PF03726.14 KNZ71804.1 - 0.11 13.0 2.3 0.35 11.4 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Calcipressin PF04847.12 KNZ71804.1 - 0.12 12.1 0.6 0.34 10.6 0.2 1.9 2 0 0 2 2 2 0 Calcipressin Erf4 PF10256.9 KNZ71804.1 - 0.19 11.9 1.5 6.9 6.8 0.2 3.2 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF4407 PF14362.6 KNZ71804.1 - 0.46 9.8 6.7 0.46 9.8 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF716 PF04819.12 KNZ71806.1 - 0.023 14.3 4.0 0.16 11.6 0.0 2.4 2 1 1 3 3 3 0 Family of unknown function (DUF716) Gemini_mov PF01708.16 KNZ71806.1 - 0.035 13.9 0.1 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein SRP54 PF00448.22 KNZ71807.1 - 1.3e-73 246.9 0.6 2.4e-73 246.0 0.6 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KNZ71807.1 - 5.9e-26 91.0 0.5 5.9e-26 91.0 0.5 3.7 4 0 0 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KNZ71807.1 - 8.4e-19 67.6 4.6 2e-18 66.4 4.6 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KNZ71807.1 - 3.3e-06 26.8 0.1 1e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KNZ71807.1 - 0.00016 21.8 0.1 0.00038 20.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KNZ71807.1 - 0.00036 19.9 0.1 0.0007 18.9 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 KNZ71807.1 - 0.00044 19.3 0.3 0.0023 17.0 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KNZ71807.1 - 0.00077 19.5 0.1 0.003 17.6 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 KNZ71807.1 - 0.0032 17.9 0.1 0.0032 17.9 0.1 2.6 4 0 0 4 4 3 1 AAA domain Fe-ADH PF00465.19 KNZ71807.1 - 0.0032 16.3 1.8 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase MipZ PF09140.11 KNZ71807.1 - 0.039 13.2 0.1 1.1 8.5 0.1 2.3 1 1 0 1 1 1 0 ATPase MipZ HTH_ParB PF17762.1 KNZ71807.1 - 0.048 13.5 1.6 0.98 9.3 0.2 2.6 2 0 0 2 2 2 0 HTH domain found in ParB protein AAA_30 PF13604.6 KNZ71807.1 - 0.053 13.2 0.1 0.053 13.2 0.1 2.6 4 0 0 4 4 4 0 AAA domain 6PF2K PF01591.18 KNZ71807.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ResIII PF04851.15 KNZ71807.1 - 0.11 12.5 2.1 7 6.6 0.4 2.7 1 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNZ71807.1 - 0.12 12.6 0.1 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2201 PF09967.9 KNZ71807.1 - 0.14 12.3 0.8 0.45 10.7 0.1 2.3 2 0 0 2 2 2 0 VWA-like domain (DUF2201) WD40 PF00400.32 KNZ71808.1 - 1.7e-07 31.8 16.7 1.6 9.7 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat SH2_2 PF14633.6 KNZ71809.1 - 1.3e-75 253.5 0.1 1.3e-75 253.5 0.1 2.9 4 0 0 4 4 2 1 SH2 domain YqgF PF14639.6 KNZ71809.1 - 1.1e-30 106.4 0.0 4.2e-30 104.5 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 KNZ71809.1 - 2.4e-28 98.5 0.0 6.1e-28 97.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 KNZ71809.1 - 9.7e-22 77.6 0.0 3.2e-21 75.9 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 KNZ71809.1 - 6.7e-20 71.5 33.8 6.7e-20 71.5 33.8 5.2 4 2 2 6 6 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KNZ71809.1 - 1.2e-06 29.3 3.4 8.3e-06 26.6 3.4 2.5 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KNZ71809.1 - 5.1e-06 26.5 0.0 5.2e-05 23.3 0.0 2.5 2 0 0 2 2 2 1 SH2 domain HHH_3 PF12836.7 KNZ71809.1 - 0.00049 20.3 0.0 0.0028 17.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif WD40_4 PF16300.5 KNZ71809.1 - 0.034 14.1 0.1 0.22 11.5 0.1 2.2 2 0 0 2 2 2 0 Type of WD40 repeat Tex_YqgF PF16921.5 KNZ71809.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Tex protein YqgF-like domain Radical_SAM PF04055.21 KNZ71809.1 - 0.13 12.6 0.4 0.83 10.0 0.2 2.5 2 0 0 2 2 2 0 Radical SAM superfamily Inv-AAD PF18785.1 KNZ71810.1 - 7.4e-27 93.8 0.0 1.3e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KNZ71810.1 - 7.8e-12 45.0 0.0 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KNZ71810.1 - 0.023 14.4 0.3 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 MafB19-like deaminase AMP-binding PF00501.28 KNZ71811.1 - 1.5e-80 270.8 0.0 2.3e-80 270.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KNZ71811.1 - 2e-72 244.4 0.0 5.3e-17 61.6 0.0 5.3 4 1 1 5 5 5 5 Condensation domain PP-binding PF00550.25 KNZ71811.1 - 6.1e-15 55.3 1.4 2.2e-06 27.9 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site GH3 PF03321.13 KNZ71811.1 - 0.0063 15.4 0.0 0.024 13.5 0.0 1.9 3 0 0 3 3 3 1 GH3 auxin-responsive promoter YAcAr PF10686.9 KNZ71811.1 - 0.038 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family K_oxygenase PF13434.6 KNZ71812.1 - 9.8e-75 251.8 0.0 1.2e-74 251.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KNZ71812.1 - 0.00011 21.5 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ71812.1 - 0.0002 20.7 0.0 0.0004 19.7 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ71812.1 - 0.0038 17.2 0.0 0.038 14.0 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ71812.1 - 0.0077 16.8 0.0 3.7 8.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ71812.1 - 0.017 14.7 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ71812.1 - 0.077 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Corona_NSP4_C PF16348.5 KNZ71812.1 - 0.16 12.8 0.0 0.31 11.9 0.0 1.4 1 0 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus Mqo PF06039.15 KNZ71812.1 - 0.21 10.1 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ribosomal_L24e PF01246.20 KNZ71813.1 - 9.3e-33 112.3 6.4 9.3e-33 112.3 6.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 KNZ71813.1 - 0.024 14.5 4.1 0.046 13.7 4.1 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif HAGH_C PF16123.5 KNZ71813.1 - 0.048 14.2 1.6 0.16 12.5 0.7 2.0 1 1 1 2 2 2 0 Hydroxyacylglutathione hydrolase C-terminus Atrophin-1 PF03154.15 KNZ71813.1 - 0.077 11.3 0.3 0.1 10.9 0.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family ATG_C PF09333.11 KNZ71814.1 - 3.7e-38 129.8 0.1 9.1e-38 128.5 0.1 1.7 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 KNZ71814.1 - 7.2e-12 45.5 0.0 2.3e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 KNZ71814.1 - 3.4e-08 33.4 0.0 2.7e-07 30.4 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 KNZ71814.1 - 0.0022 17.8 0.1 0.0061 16.4 0.1 1.7 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Lipase_GDSL PF00657.22 KNZ71815.1 - 8.1e-06 25.9 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KNZ71815.1 - 3.4e-05 24.3 0.1 9.8e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RPA_C PF08784.11 KNZ71816.1 - 1.3e-15 57.9 0.0 3.1e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KNZ71816.1 - 1e-07 31.8 0.3 2.1e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KNZ71816.1 - 0.0027 17.5 0.2 0.0044 16.8 0.2 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 HTH_6 PF01418.17 KNZ71816.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family NatB_MDM20 PF09797.9 KNZ71817.1 - 6.4e-78 262.4 8.8 3.3e-77 260.0 4.9 2.3 2 0 0 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KNZ71817.1 - 4.6e-06 27.0 6.6 0.024 15.1 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ71817.1 - 0.0002 21.9 1.8 7.7 7.6 0.0 6.4 4 1 3 7 7 7 1 Tetratricopeptide repeat BTAD PF03704.17 KNZ71817.1 - 0.025 15.0 1.1 0.083 13.3 0.0 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 KNZ71817.1 - 0.17 12.1 2.8 28 5.0 0.1 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NCE101 PF11654.8 KNZ71818.1 - 6.2e-18 64.2 0.1 9.2e-18 63.7 0.1 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 PAC3 PF10178.9 KNZ71819.1 - 0.00026 21.0 0.6 0.0011 19.0 0.6 1.9 1 1 0 1 1 1 1 Proteasome assembly chaperone 3 TruB_N PF01509.18 KNZ71821.1 - 2.7e-43 147.9 0.0 7.4e-43 146.5 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KNZ71821.1 - 0.00097 19.2 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DUF2255 PF10012.9 KNZ71821.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) DHDPS PF00701.22 KNZ71822.1 - 2.2e-28 98.8 0.0 1e-27 96.6 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PNTB PF02233.16 KNZ71823.1 - 1.2e-171 571.7 25.8 1.2e-171 571.7 25.8 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 KNZ71823.1 - 1e-71 240.6 1.1 1e-71 240.6 1.1 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KNZ71823.1 - 1.2e-41 142.1 0.2 5.1e-41 140.2 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KNZ71823.1 - 7.3e-32 109.7 3.5 7.3e-32 109.7 3.5 5.4 4 1 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 KNZ71823.1 - 0.0063 15.9 2.9 0.32 10.3 0.1 3.4 4 0 0 4 4 4 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KNZ71823.1 - 0.022 14.0 2.8 0.022 14.0 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ71823.1 - 0.027 14.7 3.7 0.11 12.8 0.7 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KNZ71823.1 - 0.056 12.5 0.6 0.1 11.6 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TPP_enzyme_M PF00205.22 KNZ71823.1 - 0.17 11.6 3.7 0.13 12.0 0.5 2.4 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.26 KNZ71823.1 - 0.38 10.7 3.8 0.23 11.4 0.3 2.6 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Nuc_sug_transp PF04142.15 KNZ71824.1 - 2.2e-94 316.2 13.9 3.2e-94 315.7 13.9 1.2 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 KNZ71824.1 - 3.3e-06 26.5 11.5 3.3e-06 26.5 11.5 1.6 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 KNZ71824.1 - 0.0011 19.2 3.8 0.0011 19.2 3.8 3.1 3 2 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 KNZ71824.1 - 0.083 12.2 10.0 0.35 10.2 0.3 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Tudor_3 PF18115.1 KNZ71826.1 - 8.7e-12 44.7 0.0 2e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT_2 PF16589.5 KNZ71826.1 - 9.3e-05 22.8 0.0 0.45 10.9 0.0 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DUF4537 PF15057.6 KNZ71826.1 - 0.0001 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) 53-BP1_Tudor PF09038.10 KNZ71826.1 - 0.00025 21.0 0.1 0.00073 19.5 0.0 1.8 2 0 0 2 2 2 1 Tumour suppressor p53-binding protein-1 Tudor BRCT PF00533.26 KNZ71826.1 - 0.00078 19.8 1.3 0.029 14.7 0.0 3.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF1325 PF07039.11 KNZ71826.1 - 0.012 15.7 0.0 0.043 13.9 0.0 1.9 2 0 0 2 2 2 0 SGF29 tudor-like domain Tudor_2 PF18104.1 KNZ71826.1 - 0.059 13.0 0.8 0.12 12.0 0.8 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain ATP11 PF06644.11 KNZ71826.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 ATP11 protein Chromo PF00385.24 KNZ71827.1 - 4.7e-09 36.0 3.6 4.7e-09 36.0 3.6 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Rad54_N PF08658.10 KNZ71828.1 - 3e-44 151.3 8.9 6.4e-44 150.3 8.9 1.5 1 0 0 1 1 1 1 Rad54 N terminal SNF2_N PF00176.23 KNZ71828.1 - 5.5e-39 133.9 0.1 4.5e-19 68.4 0.0 2.4 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ71828.1 - 1.1e-15 57.9 0.0 2.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KNZ71828.1 - 9.8e-06 24.9 1.6 3.6e-05 23.1 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KNZ71828.1 - 0.031 14.3 0.0 0.095 12.7 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GEN1_C PF18380.1 KNZ71828.1 - 0.041 14.8 7.7 2.1 9.3 0.6 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain eIF3_subunit PF08597.10 KNZ71828.1 - 0.23 11.4 11.3 0.57 10.0 0.3 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit U1snRNP70_N PF12220.8 KNZ71828.1 - 1.8 9.2 10.9 0.22 12.2 3.2 2.7 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RPN2_C PF18004.1 KNZ71828.1 - 3.7 7.5 8.7 6.9 6.6 1.0 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain GYF PF02213.16 KNZ71829.1 - 2.4e-07 30.3 0.6 6.1e-07 29.0 0.2 1.9 2 0 0 2 2 2 1 GYF domain T2SSF PF00482.23 KNZ71829.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F PQ-loop PF04193.14 KNZ71830.1 - 2.7e-39 132.7 7.1 1.5e-19 69.5 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 KNZ71830.1 - 0.051 13.6 0.3 0.051 13.6 0.3 2.2 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange RskA PF10099.9 KNZ71830.1 - 0.058 13.7 0.3 0.09 13.1 0.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CLTH PF10607.9 KNZ71831.1 - 1.1e-13 51.3 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KNZ71831.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 LisH LisH_2 PF16045.5 KNZ71831.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 LisH Ribosomal_L3 PF00297.22 KNZ71833.1 - 7.3e-20 71.3 0.3 3.7e-19 69.0 0.2 1.8 1 1 1 2 2 2 1 Ribosomal protein L3 p450 PF00067.22 KNZ71834.1 - 1.1e-51 176.0 0.0 1.2e-50 172.7 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 zf-CW PF07496.15 KNZ71834.1 - 0.19 11.8 0.1 0.48 10.5 0.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Herpes_Helicase PF02689.14 KNZ71835.1 - 5.7e-07 27.9 0.0 5.9e-07 27.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ71835.1 - 0.0022 17.8 0.3 0.0074 16.1 0.2 1.9 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Ras PF00071.22 KNZ71836.1 - 4.4e-55 185.7 0.0 5.4e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ71836.1 - 3.5e-34 117.6 0.0 5e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ71836.1 - 3e-15 56.1 0.0 3.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ71836.1 - 4e-06 26.4 0.0 4.8e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ71836.1 - 3.9e-05 23.7 0.0 5.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ71836.1 - 0.00032 20.6 0.2 0.27 11.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KNZ71836.1 - 0.00058 20.3 0.0 0.00077 19.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KNZ71836.1 - 0.0012 18.5 0.0 0.0025 17.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arrestin_C PF02752.22 KNZ71837.1 - 0.0016 18.9 3.7 0.0024 18.3 1.3 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain ARID PF01388.21 KNZ71838.1 - 7.2e-14 52.2 0.0 2.3e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KNZ71838.1 - 0.00023 20.5 1.1 0.0056 16.0 0.3 2.3 1 1 1 2 2 2 2 SWI/SNF-like complex subunit BAF250/Osa DUF1764 PF08576.10 KNZ71839.1 - 1.2e-08 35.8 6.9 5.5e-07 30.4 6.9 2.1 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) PBP_sp32 PF07222.12 KNZ71839.1 - 0.16 11.4 0.7 0.18 11.2 0.7 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Herpes_Helicase PF02689.14 KNZ71840.1 - 0.00055 18.0 0.0 0.00058 17.9 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KNZ71841.1 - 3.8e-14 52.6 0.0 4.3e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KNZ71842.1 - 1.2e-53 182.6 0.2 1.4e-53 182.3 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ71842.1 - 0.00015 21.5 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ71842.1 - 0.012 16.1 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KNZ71842.1 - 0.013 15.5 0.0 0.078 13.0 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ71842.1 - 0.05 13.3 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KNZ71842.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 KNZ71843.1 - 8.1e-26 91.4 0.0 1e-25 91.1 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ71843.1 - 0.069 13.1 0.0 0.084 12.8 0.0 1.1 1 0 0 1 1 1 0 Inovirus Gp2 Helitron_like_N PF14214.6 KNZ71844.1 - 7.3e-16 58.9 0.2 5.6e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus AAA_18 PF13238.6 KNZ71845.1 - 2.3e-31 109.0 0.0 3.7e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNZ71845.1 - 2.2e-06 27.9 0.0 0.0002 21.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 KNZ71845.1 - 1.1e-05 25.5 0.1 0.017 15.0 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 KNZ71845.1 - 4.9e-05 23.6 0.0 8.3e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ71845.1 - 8.2e-05 23.0 0.0 0.00021 21.7 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KNZ71845.1 - 9.8e-05 22.6 0.0 0.00034 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KNZ71845.1 - 0.00011 22.6 0.0 0.00042 20.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 KNZ71845.1 - 0.0035 17.3 0.0 0.0067 16.4 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain SKI PF01202.22 KNZ71845.1 - 0.0039 17.3 0.1 0.022 14.9 0.1 1.9 1 1 0 1 1 1 1 Shikimate kinase Arnt_C PF18583.1 KNZ71845.1 - 0.0053 16.3 0.9 0.023 14.3 0.0 2.3 3 0 0 3 3 3 1 Aminoarabinose transferase C-terminal domain ABC_tran PF00005.27 KNZ71845.1 - 0.0078 16.7 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 ABC transporter KTI12 PF08433.10 KNZ71845.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MeaB PF03308.16 KNZ71845.1 - 0.011 14.8 0.2 0.037 13.0 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 KNZ71845.1 - 0.015 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 KNZ71845.1 - 0.017 14.8 0.0 5.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 KNZ71845.1 - 0.019 14.3 0.2 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 KNZ71845.1 - 0.022 15.2 0.0 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ADK PF00406.22 KNZ71845.1 - 0.026 14.6 0.0 0.7 10.0 0.0 2.4 2 1 0 2 2 2 0 Adenylate kinase Viral_helicase1 PF01443.18 KNZ71845.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ71845.1 - 0.029 14.8 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 KNZ71845.1 - 0.03 13.6 0.3 0.068 12.4 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 KNZ71845.1 - 0.041 13.8 0.3 0.23 11.3 0.1 2.0 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 KNZ71845.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 KNZ71845.1 - 0.052 13.6 0.0 0.24 11.4 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KNZ71845.1 - 0.057 13.1 0.1 0.073 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KNZ71845.1 - 0.062 12.6 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KNZ71845.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KNZ71845.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 KNZ71845.1 - 0.2 11.4 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 KNZ71845.1 - 0.3 11.4 2.1 0.28 11.5 0.5 1.8 2 1 0 2 2 2 0 AAA domain Sin_N PF04801.13 KNZ71846.1 - 1e-21 77.7 0.0 1.7e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region DnaJ PF00226.31 KNZ71848.1 - 1.4e-19 69.9 0.6 2.5e-19 69.2 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 KNZ71848.1 - 0.0067 16.7 1.6 0.011 16.1 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 KNZ71848.1 - 0.81 9.5 5.8 1.5 8.6 5.8 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KNZ71848.1 - 1.8 8.6 9.5 3.1 7.9 9.5 1.4 1 0 0 1 1 1 0 Glycine zipper Bacteriocin_IIc PF10439.9 KNZ71848.1 - 7.2 6.8 9.5 14 5.8 9.5 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Pex24p PF06398.11 KNZ71849.1 - 0.11 11.4 2.1 0.15 11.0 2.1 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin gag-asp_proteas PF13975.6 KNZ71850.1 - 0.035 14.7 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease LIM PF00412.22 KNZ71852.1 - 1.6e-11 44.2 24.7 1.3e-05 25.4 4.7 5.4 5 0 0 5 5 5 3 LIM domain HhH-GPD PF00730.25 KNZ71853.1 - 0.00014 22.2 0.0 0.0002 21.8 0.0 1.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein FAM195 PF14799.6 KNZ71853.1 - 0.14 12.5 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 FAM195 family FMN_dh PF01070.18 KNZ71854.1 - 2.7e-99 332.5 0.0 3.4e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KNZ71854.1 - 1.7e-21 76.2 0.0 3.3e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.15 KNZ71854.1 - 0.004 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 KNZ71854.1 - 0.006 15.8 0.1 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KNZ71854.1 - 0.019 14.0 1.7 0.088 11.8 0.1 2.6 2 1 1 3 3 3 0 IMP dehydrogenase / GMP reductase domain BLOC1_2 PF10046.9 KNZ71855.1 - 0.09 13.1 0.1 0.18 12.1 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 KNZ71855.1 - 0.11 13.0 0.3 0.21 12.0 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SAP PF02037.27 KNZ71855.1 - 0.16 11.7 0.2 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 SAP domain Pkinase PF00069.25 KNZ71856.1 - 8.3e-65 218.8 0.0 9.7e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71856.1 - 7.6e-26 90.9 0.0 1.2e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ71856.1 - 8.8e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KNZ71856.1 - 0.042 12.8 0.1 0.063 12.2 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KNZ71856.1 - 0.053 12.9 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ71856.1 - 0.092 12.7 0.3 0.3 11.0 0.4 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ71856.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Helitron_like_N PF14214.6 KNZ71857.1 - 1.8e-07 31.6 0.7 2.8e-07 30.9 0.7 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ71859.1 - 9.5e-28 97.4 0.1 1e-27 97.3 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ71859.1 - 0.002 18.1 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ71859.1 - 0.011 16.1 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KNZ71859.1 - 0.034 13.9 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KNZ71859.1 - 0.077 12.7 0.1 0.088 12.5 0.1 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Aldo_ket_red PF00248.21 KNZ71860.1 - 3.5e-68 230.0 0.0 3.9e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PAN_4 PF14295.6 KNZ71861.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.1 2 1 0 2 2 2 0 PAN domain ComFB PF10719.9 KNZ71861.1 - 0.19 11.9 0.3 0.33 11.1 0.3 1.3 1 0 0 1 1 1 0 Late competence development protein ComFB Transp_cyt_pur PF02133.15 KNZ71862.1 - 1.4e-112 376.7 35.9 1.6e-112 376.5 35.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.25 KNZ71863.1 - 6.2e-48 163.5 0.0 9e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71863.1 - 1.9e-47 161.7 0.0 2.7e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KNZ71863.1 - 5.8e-07 29.3 6.7 1.3e-06 28.2 6.7 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_fungal PF17667.1 KNZ71863.1 - 0.0055 15.5 0.0 0.0085 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase C1_2 PF03107.16 KNZ71863.1 - 0.017 15.4 2.5 0.039 14.3 2.5 1.7 1 0 0 1 1 1 0 C1 domain Kdo PF06293.14 KNZ71863.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ71863.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-HC5HC2H PF13771.6 KNZ71863.1 - 0.19 12.0 3.0 0.41 10.9 3.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Haspin_kinase PF12330.8 KNZ71863.1 - 0.26 10.2 0.0 0.46 9.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PHD PF00628.29 KNZ71863.1 - 0.56 10.2 10.0 1.5 8.8 10.0 1.7 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.27 KNZ71864.1 - 6.3e-24 83.7 4.0 1e-15 57.4 0.2 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Aim19 PF10315.9 KNZ71865.1 - 0.09 13.1 0.2 0.15 12.4 0.2 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 Herpes_U47 PF05467.11 KNZ71865.1 - 7.8 4.5 6.7 11 4.0 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 MCR_D PF02505.14 KNZ71866.1 - 0.064 13.1 0.0 0.067 13.0 0.0 1.0 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D SE PF08491.10 KNZ71868.1 - 1.8e-94 315.9 0.0 2.2e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KNZ71868.1 - 0.00015 21.2 0.0 0.00029 20.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNZ71868.1 - 0.00039 20.1 0.1 0.00054 19.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase 4HBT PF03061.22 KNZ71869.1 - 3.7e-07 30.4 0.0 0.0029 17.9 0.0 2.5 2 0 0 2 2 2 2 Thioesterase superfamily DUF1688 PF07958.11 KNZ71871.1 - 1.5e-161 537.9 0.0 1.7e-161 537.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) GEN1_C PF18380.1 KNZ71872.1 - 4.7e-28 98.2 0.2 1.5e-27 96.5 0.2 2.0 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KNZ71872.1 - 4.2e-18 65.5 0.0 1.3e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KNZ71872.1 - 0.0011 19.5 0.0 0.0041 17.6 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_3 PF00933.21 KNZ71873.1 - 1.4e-79 267.7 0.0 1.8e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain VHS PF00790.19 KNZ71874.1 - 5.2e-07 29.6 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 VHS domain Pkinase PF00069.25 KNZ71875.1 - 3.5e-21 75.7 0.0 9.4e-19 67.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ71875.1 - 5.6e-20 71.7 0.0 7.8e-17 61.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ71875.1 - 0.00084 18.2 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ71875.1 - 0.0028 17.6 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ71875.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Fructosamin_kin PF03881.14 KNZ71875.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 KNZ71875.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 KNZ71876.1 - 8.8e-33 112.0 0.1 5.1e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ71876.1 - 1.6e-11 44.2 0.0 2.5e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KNZ71876.1 - 0.0068 16.4 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif OB_RNB PF08206.11 KNZ71876.1 - 0.0075 15.9 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KNZ71876.1 - 0.056 13.5 0.0 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GAT PF03127.14 KNZ71877.1 - 8e-08 32.5 1.3 7.6e-05 22.9 0.1 2.5 2 0 0 2 2 2 2 GAT domain VHS PF00790.19 KNZ71877.1 - 1.2e-07 31.7 0.1 3.6e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 VHS domain AA_permease_2 PF13520.6 KNZ71878.1 - 3.5e-61 207.3 51.7 4.4e-61 207.0 51.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ71878.1 - 5.6e-12 45.0 45.8 8.5e-12 44.4 45.8 1.2 1 0 0 1 1 1 1 Amino acid permease UCR_UQCRX_QCR9 PF05365.12 KNZ71879.1 - 0.037 14.0 1.0 0.11 12.4 1.0 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-C2H2_4 PF13894.6 KNZ71879.1 - 9.2 7.4 6.4 6.2 8.0 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Amino_oxidase PF01593.24 KNZ71880.1 - 8.7e-63 213.2 0.0 2.8e-62 211.5 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ71880.1 - 6.8e-11 42.2 0.5 2.6e-10 40.4 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KNZ71880.1 - 0.00055 19.3 0.0 0.2 10.8 0.1 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KNZ71880.1 - 0.0051 16.2 0.1 0.0077 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KNZ71880.1 - 0.0052 16.1 0.2 0.0087 15.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KNZ71880.1 - 0.0082 15.3 0.3 0.013 14.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNZ71880.1 - 0.014 15.0 0.2 0.28 10.7 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KNZ71880.1 - 0.023 14.0 0.2 0.1 11.8 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KNZ71880.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KNZ71880.1 - 0.25 10.0 0.4 0.57 8.8 0.4 1.6 1 0 0 1 1 1 0 HI0933-like protein DUF89 PF01937.19 KNZ71881.1 - 4.4e-90 302.2 0.0 6.1e-81 272.1 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function DUF89 BolA PF01722.18 KNZ71883.1 - 2.8e-16 59.5 0.0 6e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein Amidohydro_2 PF04909.14 KNZ71884.1 - 3.4e-16 59.9 0.0 5.4e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Adenylsucc_synt PF00709.21 KNZ71885.1 - 6.3e-171 568.9 0.0 7.1e-171 568.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase COX16 PF14138.6 KNZ71886.1 - 3.8e-31 107.4 0.0 4.6e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 ATP-synt_J PF04911.12 KNZ71887.1 - 1.1e-23 82.5 0.0 1.6e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase j chain Clathrin PF00637.20 KNZ71888.1 - 8.9e-20 71.0 1.4 2.5e-13 50.1 0.9 2.7 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 KNZ71888.1 - 3.4e-09 36.6 8.6 6.9e-09 35.6 8.6 1.6 1 0 0 1 1 1 1 Zinc-finger VPS11_C PF12451.8 KNZ71888.1 - 2e-05 24.7 0.8 6.3e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.6 KNZ71888.1 - 0.00059 19.6 8.3 0.0011 18.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ71888.1 - 0.017 15.4 8.1 0.035 14.4 8.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 KNZ71888.1 - 0.023 14.7 7.6 0.041 13.9 7.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain TPR_16 PF13432.6 KNZ71888.1 - 0.057 14.1 2.7 7.5 7.3 1.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 KNZ71888.1 - 0.26 11.2 1.4 0.63 10.0 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 KNZ71888.1 - 0.36 11.2 7.2 0.78 10.1 7.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KNZ71888.1 - 1.7 8.7 7.3 3.8 7.6 7.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Antistasin PF02822.14 KNZ71889.1 - 0.093 13.4 0.4 0.21 12.3 0.4 1.6 1 0 0 1 1 1 0 Antistasin family HSP70 PF00012.20 KNZ71890.1 - 9.8e-263 872.8 8.1 1.1e-262 872.6 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNZ71890.1 - 5.1e-19 68.3 1.4 5e-18 65.0 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KNZ71890.1 - 0.0042 16.4 0.3 0.012 14.8 0.3 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 KNZ71890.1 - 0.0089 15.0 0.4 0.32 9.9 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FIVAR PF07554.13 KNZ71890.1 - 0.31 11.8 4.0 2.1 9.2 0.1 3.5 3 1 0 3 3 3 0 FIVAR domain Acetyltransf_1 PF00583.25 KNZ71891.1 - 3.8e-17 62.6 0.0 5.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ71891.1 - 2.3e-09 37.2 0.0 3.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ71891.1 - 3.3e-09 36.6 0.0 5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KNZ71891.1 - 1e-08 35.5 0.0 1.5e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNZ71891.1 - 8.6e-06 26.5 0.0 1.1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KNZ71891.1 - 1.2e-05 25.4 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KNZ71891.1 - 3.8e-05 23.4 0.0 6.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNZ71891.1 - 0.022 14.9 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KNZ71891.1 - 0.088 12.9 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_18 PF18014.1 KNZ71891.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PP2C PF00481.21 KNZ71895.1 - 1.4e-75 254.2 0.0 2.1e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KNZ71895.1 - 0.0023 17.6 0.0 0.0039 16.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C GMC_oxred_N PF00732.19 KNZ71896.1 - 2.3e-61 207.8 0.0 3.4e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ71896.1 - 1.7e-35 122.7 0.0 3.7e-35 121.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ71896.1 - 0.00011 22.4 0.0 0.00034 20.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ71896.1 - 0.00014 21.0 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ71896.1 - 0.00019 20.6 0.0 0.0086 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ71896.1 - 0.001 18.4 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ71896.1 - 0.0046 16.6 0.1 0.029 14.0 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ71896.1 - 0.0071 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KNZ71896.1 - 0.069 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 KNZ71896.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain YL1_C PF08265.11 KNZ71897.1 - 1.6e-15 56.5 0.8 2.4e-15 56.0 0.8 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CPL PF08144.11 KNZ71898.1 - 9e-35 120.1 0.0 3.3e-31 108.6 0.0 3.5 3 0 0 3 3 3 3 CPL (NUC119) domain Chromo PF00385.24 KNZ71900.1 - 1.6e-08 34.3 0.1 2.1e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ71900.1 - 0.023 14.9 0.1 0.027 14.7 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Spc7 PF08317.11 KNZ71901.1 - 0.067 12.1 2.9 0.084 11.7 2.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein NST1 PF13945.6 KNZ71902.1 - 2.2e-54 184.5 0.0 2.2e-54 184.5 0.0 4.8 2 1 3 5 5 5 1 Salt tolerance down-regulator NdhN PF11909.8 KNZ71903.1 - 0.11 12.2 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 NADH-quinone oxidoreductase cyanobacterial subunit N LRR_4 PF12799.7 KNZ71904.1 - 0.041 14.3 0.3 0.5 10.9 0.0 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ71904.1 - 0.068 12.9 2.0 0.27 11.0 0.1 3.0 4 0 0 4 4 4 0 Leucine rich repeat ACOX PF01756.19 KNZ71905.1 - 1.1e-33 116.4 0.1 2.5e-33 115.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KNZ71905.1 - 7.6e-18 65.3 0.0 1.4e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KNZ71905.1 - 1.9e-05 24.8 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KNZ71905.1 - 0.00074 19.7 0.0 0.00074 19.7 0.0 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain La PF05383.17 KNZ71906.1 - 2.6e-20 72.2 0.0 5.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 KNZ71906.1 - 7.8e-05 22.7 0.0 0.00022 21.2 0.0 1.8 1 0 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 KNZ71906.1 - 0.00018 21.2 0.4 0.00051 19.8 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.27 KNZ71907.1 - 7.2e-38 128.4 1.9 1.4e-13 50.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KNZ71907.1 - 0.0051 16.0 0.1 0.83 8.8 0.0 2.4 2 1 0 2 2 2 2 Gammaproteobacterial serine protease Tim17 PF02466.19 KNZ71907.1 - 0.014 15.8 0.3 7.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Glyco_hydro_79C PF16862.5 KNZ71908.1 - 9.9e-06 26.4 0.1 9e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_79C PF16862.5 KNZ71912.1 - 1.6e-15 57.8 0.5 7.5e-15 55.7 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain Sugar_tr PF00083.24 KNZ71913.1 - 2.3e-85 287.2 14.7 2.5e-85 287.1 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ71913.1 - 1.3e-24 86.9 34.9 5.5e-16 58.4 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KNZ71913.1 - 0.013 14.4 4.1 0.18 10.7 1.5 2.3 2 0 0 2 2 2 0 Sugar-tranasporters, 12 TM DUF3792 PF12670.7 KNZ71913.1 - 8.6 6.6 19.9 0.99 9.6 5.8 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF3792) SH3_2 PF07653.17 KNZ71914.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.5 1 1 0 1 1 1 0 Variant SH3 domain Nyv1_N PF09426.10 KNZ71914.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Ferlin_C PF16165.5 KNZ71916.1 - 0.17 11.8 1.5 0.19 11.7 0.1 1.6 1 1 1 2 2 2 0 Ferlin C-terminus Pkinase_fungal PF17667.1 KNZ71917.1 - 9.6e-47 159.6 0.0 1.4e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF5318 PF17249.2 KNZ71917.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) DNA_pol_B_palm PF14792.6 KNZ71918.1 - 6.2e-27 94.1 0.0 1.4e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KNZ71918.1 - 1.4e-20 72.9 0.3 2.9e-19 68.6 0.1 2.7 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KNZ71918.1 - 2.7e-18 65.9 0.0 7.2e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 KNZ71918.1 - 1e-15 57.8 0.8 2.7e-15 56.5 0.5 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.26 KNZ71918.1 - 0.024 15.0 0.0 0.49 10.8 0.0 2.8 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain HHH PF00633.23 KNZ71918.1 - 0.025 14.5 0.2 0.25 11.3 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 KNZ71918.1 - 0.06 14.0 0.2 13 6.5 0.1 3.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain Methyltransf_31 PF13847.6 KNZ71919.1 - 1.1e-11 44.8 0.0 4e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ71919.1 - 4.3e-11 42.9 0.0 7.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ71919.1 - 1.7e-10 41.4 0.0 4.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ71919.1 - 1.8e-08 34.9 0.0 3.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ71919.1 - 9.6e-07 29.5 0.0 3.4e-06 27.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 KNZ71919.1 - 2e-05 24.1 0.0 7.4e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KNZ71919.1 - 0.0025 18.0 0.0 0.0039 17.3 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KNZ71919.1 - 0.0076 15.6 0.0 0.31 10.3 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KNZ71919.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_M16 PF00675.20 KNZ71920.1 - 6e-24 84.7 0.1 9.7e-24 84.0 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KNZ71920.1 - 0.00037 20.6 0.0 0.04 13.9 0.0 2.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain Pkinase_fungal PF17667.1 KNZ71921.1 - 2.5e-47 161.6 0.1 8.6e-47 159.8 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Pkinase_fungal PF17667.1 KNZ71924.1 - 7e-14 51.4 0.0 1.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DUF5318 PF17249.2 KNZ71924.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5318) Apolipoprotein PF01442.18 KNZ71924.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Peptidase_S9 PF00326.21 KNZ71925.1 - 1.8e-24 86.4 0.0 1.7e-14 53.8 0.0 2.1 1 1 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KNZ71925.1 - 0.0036 16.6 0.0 0.01 15.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ71925.1 - 0.023 14.4 0.0 0.048 13.3 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1513 PF07433.11 KNZ71925.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) Ribosomal_60s PF00428.19 KNZ71926.1 - 1.9e-26 92.5 6.2 1.9e-26 92.5 6.2 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein MMR_HSR1 PF01926.23 KNZ71927.1 - 1.8e-06 28.0 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 KNZ71927.1 - 0.00061 19.2 0.0 0.0062 15.8 0.0 2.1 1 1 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 KNZ71927.1 - 0.0014 18.5 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KNZ71927.1 - 0.0049 17.3 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 KNZ71927.1 - 0.031 14.5 0.0 0.099 12.9 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KNZ71927.1 - 0.055 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KNZ71927.1 - 0.087 13.1 0.0 0.36 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KNZ71927.1 - 0.18 11.3 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KNZ71927.1 - 0.18 12.3 0.0 0.44 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter UBN_AB PF14075.6 KNZ71928.1 - 3.6e-40 138.0 0.3 3.6e-40 138.0 0.3 2.1 2 0 0 2 2 2 1 Ubinuclein conserved middle domain HUN PF08729.10 KNZ71928.1 - 1.7e-14 53.5 0.7 4.1e-14 52.3 0.7 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Mito_fiss_reg PF05308.11 KNZ71928.1 - 0.097 12.7 6.4 0.23 11.5 6.4 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator VIR_N PF15912.5 KNZ71928.1 - 0.12 12.0 9.6 0.034 13.8 5.6 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal FXR_C3 PF16097.5 KNZ71928.1 - 0.22 12.2 0.1 0.22 12.2 0.1 3.0 3 0 0 3 3 3 0 Fragile X-related 1 protein C-terminal region 3 Herpes_DNAp_acc PF04929.12 KNZ71928.1 - 7.7 5.4 10.6 18 4.2 10.6 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ACPS PF01648.20 KNZ71929.1 - 0.0078 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Peptidase_C33 PF05412.12 KNZ71929.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase gag-asp_proteas PF13975.6 KNZ71931.1 - 1.5e-05 25.5 0.0 7.8e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ71931.1 - 0.00013 22.6 0.0 0.0003 21.4 0.0 1.7 2 1 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KNZ71931.1 - 0.002 17.9 0.3 0.029 14.2 0.1 2.1 1 1 1 2 2 2 1 Aspartyl protease CCSAP PF15748.5 KNZ71933.1 - 1.1 9.3 10.1 1.7 8.8 10.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Cation_ATPase_C PF00689.21 KNZ71935.1 - 1.4e-40 138.9 5.7 1.4e-40 138.9 5.7 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KNZ71935.1 - 2.4e-40 138.0 1.0 2.4e-40 138.0 1.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KNZ71935.1 - 3.2e-19 70.1 0.0 1e-08 35.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ71935.1 - 2.1e-17 63.0 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNZ71935.1 - 1.3e-05 24.8 0.0 3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNZ71935.1 - 0.00036 20.4 0.8 0.0008 19.2 0.8 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KNZ71935.1 - 0.074 13.4 0.0 5.9 7.2 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FA_desaturase PF00487.24 KNZ71935.1 - 2.5 7.9 12.4 1.5 8.6 1.0 3.3 3 0 0 3 3 3 0 Fatty acid desaturase Cation_ATPase_C PF00689.21 KNZ71936.1 - 7.2e-43 146.4 3.0 7.2e-43 146.4 3.0 3.2 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KNZ71936.1 - 4.8e-41 140.3 1.8 4.8e-41 140.3 1.8 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KNZ71936.1 - 1.8e-22 80.7 0.1 4.4e-20 72.9 0.0 3.9 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ71936.1 - 4.5e-18 65.1 0.0 1.2e-17 63.8 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNZ71936.1 - 2.5e-08 33.5 0.0 6.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNZ71936.1 - 0.00012 21.9 0.8 0.00078 19.3 0.9 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KNZ71936.1 - 0.0025 18.2 0.0 0.0076 16.7 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 KNZ71936.1 - 9 6.1 8.4 0.35 10.7 0.3 2.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) Podoplanin PF05808.11 KNZ71937.1 - 0.00038 20.6 2.3 0.0011 19.1 2.3 1.8 1 0 0 1 1 1 1 Podoplanin AMP-binding PF00501.28 KNZ71938.1 - 3.8e-20 71.9 0.0 2.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme GH3 PF03321.13 KNZ71938.1 - 0.01 14.8 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Tyr-DNA_phospho PF06087.12 KNZ71939.1 - 1.7e-53 182.1 0.0 2.6e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Importin_rep PF18773.1 KNZ71941.1 - 8.8e-12 44.5 0.0 5.5e-11 42.0 0.0 2.3 2 0 0 2 2 2 1 Importin 13 repeat Xpo1 PF08389.12 KNZ71941.1 - 3.3e-11 43.5 0.2 2.9e-09 37.1 0.1 3.4 2 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KNZ71941.1 - 0.00029 20.7 0.1 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Flu_M1_C PF08289.11 KNZ71941.1 - 0.0012 19.0 0.0 0.0045 17.2 0.0 2.0 1 0 0 1 1 1 1 Influenza Matrix protein (M1) C-terminal domain Importin_rep_3 PF18806.1 KNZ71941.1 - 0.0028 17.6 0.0 0.015 15.4 0.0 2.3 1 0 0 1 1 1 1 Importin 13 repeat UME PF08064.13 KNZ71941.1 - 2.9 7.8 7.8 4.6 7.2 1.1 3.8 3 1 0 3 3 3 0 UME (NUC010) domain TERT_thumb PF17984.1 KNZ71942.1 - 0.034 14.0 0.1 0.055 13.4 0.1 1.3 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain Say1_Mug180 PF10340.9 KNZ71944.1 - 5.4e-23 81.4 0.0 7.6e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KNZ71944.1 - 7.6e-19 68.4 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KNZ71944.1 - 0.034 13.0 0.1 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ71945.1 - 4.1e-20 72.5 0.0 6.1e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KNZ71945.1 - 5.6e-20 71.5 0.0 8.1e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KNZ71945.1 - 0.1 11.5 0.3 0.51 9.1 0.1 1.9 2 0 0 2 2 2 0 Carboxylesterase family AMP-binding PF00501.28 KNZ71947.1 - 1.9e-94 316.6 0.2 2.5e-94 316.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2104 PF09877.9 KNZ71947.1 - 0.015 15.6 0.4 0.037 14.3 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) AMP-binding_C PF13193.6 KNZ71947.1 - 0.032 15.2 0.0 0.11 13.5 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Say1_Mug180 PF10340.9 KNZ71948.1 - 4.6e-22 78.4 0.0 6.6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KNZ71948.1 - 6.8e-19 68.6 0.0 9.9e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KNZ71948.1 - 0.13 11.1 0.0 0.51 9.1 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family DUF1158 PF06643.11 KNZ71948.1 - 0.55 10.8 2.2 8.2 7.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1158) tRNA-synt_1f PF01921.18 KNZ71949.1 - 0.18 10.7 0.1 0.66 8.8 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) Glyco_hydro_38N PF01074.22 KNZ71950.1 - 1e-74 251.6 0.4 1.5e-74 251.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KNZ71950.1 - 9.2e-51 172.9 0.0 1.4e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KNZ71950.1 - 2.6e-09 37.1 0.0 1e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KNZ71950.1 - 1.8e-06 28.0 0.0 5.7e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KNZ71950.1 - 0.02 14.1 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 MMR_HSR1 PF01926.23 KNZ71951.1 - 2.1e-06 27.8 0.0 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KNZ71951.1 - 0.012 15.4 0.2 0.044 13.6 0.1 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 KNZ71951.1 - 0.028 14.3 0.0 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KNZ71951.1 - 0.11 12.1 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNZ71952.1 - 3.4e-08 33.6 0.0 7.1e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KNZ71952.1 - 0.00028 20.4 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KNZ71952.1 - 0.0014 17.9 0.2 0.0062 15.7 0.2 1.9 1 1 1 2 2 2 1 G-protein alpha subunit DUF2326 PF10088.9 KNZ71952.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2326) RsgA_GTPase PF03193.16 KNZ71952.1 - 0.0058 16.6 0.0 0.052 13.4 0.0 2.2 3 0 0 3 3 3 1 RsgA GTPase Roc PF08477.13 KNZ71952.1 - 0.0064 16.7 0.0 0.036 14.3 0.0 2.1 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KNZ71952.1 - 0.018 14.3 0.0 0.29 10.4 0.0 2.2 3 0 0 3 3 3 0 Septin AAA_22 PF13401.6 KNZ71952.1 - 0.019 15.3 0.1 0.18 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KNZ71952.1 - 0.032 13.8 0.0 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KNZ71952.1 - 0.034 14.1 0.3 0.08 12.9 0.2 2.0 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 KNZ71952.1 - 0.043 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 KNZ71952.1 - 0.095 12.8 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 KNZ71952.1 - 0.14 11.9 0.1 0.34 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain TAL_FSA PF00923.19 KNZ71953.1 - 2.1e-60 204.5 0.0 2.7e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase 7TM-7TMR_HD PF07698.11 KNZ71954.1 - 0.092 12.5 13.4 0.51 10.1 6.9 2.1 1 1 1 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF2700 PF10912.8 KNZ71954.1 - 0.21 11.6 9.7 2.5 8.1 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2700) AAA_12 PF13087.6 KNZ71955.1 - 1.1e-31 110.1 0.0 2.4e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ71955.1 - 2e-16 60.3 0.0 1.6e-15 57.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ71955.1 - 3.7e-13 49.9 0.0 8.6e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KNZ71955.1 - 1.5e-12 48.1 0.0 1e-11 45.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KNZ71955.1 - 1.9e-05 24.5 0.2 0.57 9.9 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KNZ71955.1 - 8.8e-05 22.0 0.0 0.00092 18.7 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 KNZ71955.1 - 0.01 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KNZ71955.1 - 0.011 15.1 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KNZ71955.1 - 0.017 15.4 0.0 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 KNZ71955.1 - 0.03 14.2 0.0 0.76 9.6 0.0 2.3 2 0 0 2 2 2 0 Helicase UvrD_C_2 PF13538.6 KNZ71955.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KNZ71955.1 - 0.037 13.6 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 KNZ71955.1 - 0.063 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ71955.1 - 0.081 13.3 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Flavi_DEAD PF07652.14 KNZ71955.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.12 KNZ71955.1 - 0.091 12.7 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain UvrD_C PF13361.6 KNZ71955.1 - 0.096 12.0 0.0 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PMSR PF01625.21 KNZ71956.1 - 8.5e-60 201.4 0.2 9.9e-60 201.1 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase UCR_hinge PF02320.16 KNZ71957.1 - 4.2e-12 46.1 2.8 8.1e-12 45.2 2.8 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein C8 PF08742.11 KNZ71957.1 - 0.034 14.6 0.9 0.054 13.9 0.9 1.3 1 0 0 1 1 1 0 C8 domain EMC3_TMCO1 PF01956.16 KNZ71959.1 - 0.2 11.4 3.0 12 5.6 0.0 2.2 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF1917 PF08939.10 KNZ71960.1 - 1.2e-34 120.4 0.2 1.4e-30 107.1 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1917) Aldedh PF00171.22 KNZ71961.1 - 7.7e-72 242.3 0.0 1e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamin_M PF01031.20 KNZ71962.1 - 3.1e-28 98.8 0.0 1.2e-27 96.9 0.0 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KNZ71962.1 - 2.3e-22 79.8 0.0 4.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KNZ71962.1 - 1.7e-10 40.9 0.2 1.1e-09 38.4 0.2 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_29 PF13555.6 KNZ71962.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KNZ71962.1 - 0.12 12.8 0.0 0.43 11.1 0.0 2.0 1 1 0 1 1 1 0 ABC transporter MFS_1 PF07690.16 KNZ71963.1 - 8e-37 127.0 36.3 8e-37 127.0 36.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily BacteriocIIc_cy PF12173.8 KNZ71963.1 - 0.028 14.7 1.5 0.098 12.9 1.5 2.0 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like Oxidored_FMN PF00724.20 KNZ71964.1 - 1.1e-96 324.1 0.0 1.3e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3602 PF12223.8 KNZ71965.1 - 7e-25 87.4 30.1 9.9e-06 26.1 4.9 5.7 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) ArAE_2 PF10334.9 KNZ71966.1 - 1.8e-49 168.7 0.0 2.7e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KNZ71966.1 - 6.3e-46 157.4 0.0 5.4e-44 151.0 0.0 2.4 1 1 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KNZ71966.1 - 1.3e-09 38.3 15.2 1.3e-09 38.3 15.2 3.2 3 1 0 3 3 3 1 Fusaric acid resistance protein-like CSG2 PF16965.5 KNZ71967.1 - 0.91 8.4 3.1 1.1 8.1 3.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Rep_1 PF01446.17 KNZ71967.1 - 1 8.8 5.8 0.23 10.9 1.6 2.0 1 1 1 2 2 2 0 Replication protein PA26 PF04636.13 KNZ71967.1 - 4.4 6.1 6.6 6.3 5.6 6.6 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM76 PF16046.5 KNZ71967.1 - 6.4 6.0 16.3 0.38 10.1 11.4 1.4 2 0 0 2 2 2 0 FAM76 protein Asp_protease_2 PF13650.6 KNZ71968.1 - 0.0031 18.1 0.0 0.0077 16.8 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ71968.1 - 0.0079 16.7 0.0 0.017 15.7 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease ICMT PF04140.14 KNZ71969.1 - 5.3e-11 42.8 1.3 7.6e-11 42.3 0.2 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KNZ71969.1 - 3.1e-10 40.4 0.7 3.7e-09 36.9 0.7 2.3 1 1 0 1 1 1 1 Phospholipid methyltransferase NADH5_C PF06455.11 KNZ71969.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus MFS_1 PF07690.16 KNZ71970.1 - 1.6e-19 70.1 19.3 2.8e-19 69.2 19.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily ImcF-related_N PF14331.6 KNZ71971.1 - 0.0045 16.4 0.3 0.0083 15.5 0.3 1.4 1 0 0 1 1 1 1 ImcF-related N-terminal domain GTP_EFTU PF00009.27 KNZ71971.1 - 0.019 14.5 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Pmp3 PF01679.17 KNZ71971.1 - 0.068 13.4 2.8 0.22 11.8 1.0 2.4 2 0 0 2 2 2 0 Proteolipid membrane potential modulator Aldo_ket_red PF00248.21 KNZ71972.1 - 7.9e-59 199.3 0.0 2.3e-58 197.7 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1896 PF08989.10 KNZ71974.1 - 0.0044 17.1 0.3 5.9 7.0 0.1 3.2 2 2 1 3 3 3 2 Domain of unknown function (DUF1896) RYDR_ITPR PF01365.21 KNZ71974.1 - 0.089 12.2 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 RIH domain Mistic PF11458.8 KNZ71974.1 - 0.21 11.6 1.7 0.39 10.7 0.5 2.1 2 0 0 2 2 2 0 Membrane-integrating protein Mistic SURF2 PF05477.11 KNZ71975.1 - 0.083 12.6 12.6 0.091 12.4 12.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 KNZ71975.1 - 0.093 12.1 22.6 0.095 12.0 22.6 1.0 1 0 0 1 1 1 0 BUD22 DUF4746 PF15928.5 KNZ71975.1 - 0.48 9.8 14.3 0.56 9.6 14.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Zip PF02535.22 KNZ71975.1 - 0.74 9.0 8.9 0.82 8.8 8.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Fibrinogen_aC PF12160.8 KNZ71975.1 - 0.78 9.6 10.8 0.29 11.0 7.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha C domain RR_TM4-6 PF06459.12 KNZ71975.1 - 1.1 9.0 12.7 1.4 8.7 12.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 KNZ71975.1 - 1.2 8.0 17.4 1.4 7.8 17.4 1.2 1 0 0 1 1 1 0 Paf1 Raftlin PF15250.6 KNZ71975.1 - 1.4 7.6 10.1 1.5 7.5 10.1 1.0 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 KNZ71975.1 - 2.6 6.2 26.3 2.9 6.0 26.3 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 KNZ71975.1 - 3.1 6.5 12.7 3.5 6.3 12.7 1.0 1 0 0 1 1 1 0 Presenilin Roughex PF06020.11 KNZ71975.1 - 3.2 6.8 16.6 4.3 6.3 16.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein FAM163 PF15069.6 KNZ71975.1 - 3.6 8.0 4.8 5 7.6 4.8 1.2 1 0 0 1 1 1 0 FAM163 family SDA1 PF05285.12 KNZ71975.1 - 3.8 6.8 28.6 4.5 6.6 28.6 1.0 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 KNZ71975.1 - 3.8 6.4 8.4 4.8 6.0 8.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 KNZ71975.1 - 4.4 6.0 13.2 4.5 5.9 13.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SLC12 PF03522.15 KNZ71975.1 - 4.8 6.1 7.5 5.2 6.0 7.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Trypan_PARP PF05887.11 KNZ71975.1 - 5.4 7.0 14.7 7 6.6 14.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM60A PF15396.6 KNZ71975.1 - 6.2 6.8 7.2 7.4 6.5 7.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.11 KNZ71975.1 - 6.8 6.2 23.0 8.4 5.9 23.0 1.2 1 0 0 1 1 1 0 PPP4R2 Pes-10 PF07149.11 KNZ71975.1 - 8.6 5.3 23.0 11 5.0 23.0 1.0 1 0 0 1 1 1 0 Pes-10 CDC45 PF02724.14 KNZ71975.1 - 9.2 4.4 22.1 11 4.2 22.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SCNM1_acidic PF15805.5 KNZ71978.1 - 0.046 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 DUF2321 PF10083.9 KNZ71978.1 - 0.073 12.7 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF1349 PF07081.11 KNZ71979.1 - 2.7e-12 46.8 0.0 3.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PLAC8 PF04749.17 KNZ71980.1 - 1.9e-24 86.5 6.8 2.4e-24 86.2 6.8 1.1 1 0 0 1 1 1 1 PLAC8 family CaM_binding PF07839.11 KNZ71983.1 - 0.0097 16.6 0.3 0.017 15.9 0.3 1.3 1 0 0 1 1 1 1 Plant calmodulin-binding domain Glyco_hydro_10 PF00331.20 KNZ71984.1 - 2.1e-28 99.4 1.1 4.4e-15 55.6 0.2 2.9 1 1 2 3 3 3 3 Glycosyl hydrolase family 10 ATG13 PF10033.9 KNZ71985.1 - 2.2e-34 119.2 0.0 6.5e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 N2227 PF07942.12 KNZ71986.1 - 3.7e-62 210.0 0.0 4.6e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KNZ71986.1 - 7.2e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ71986.1 - 0.0073 17.0 0.0 0.017 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Histone PF00125.24 KNZ71987.1 - 4.9e-50 169.3 3.8 5.5e-50 169.1 3.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNZ71987.1 - 2.6e-05 24.5 0.1 4.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNZ71987.1 - 5.2e-05 23.3 0.1 0.0001 22.4 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KNZ71987.1 - 6.1e-05 23.6 2.5 7.7e-05 23.3 2.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KNZ71987.1 - 0.00072 19.8 0.1 0.0014 18.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KNZ71987.1 - 0.089 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Hist_deacetyl PF00850.19 KNZ71988.1 - 1.1e-53 182.8 0.1 1.8e-53 182.0 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Mito_carr PF00153.27 KNZ71989.1 - 4.1e-55 183.7 5.1 1e-19 70.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF202 PF02656.15 KNZ71990.1 - 1.1e-16 61.0 6.2 1.1e-16 61.0 6.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) AnkUBD PF18418.1 KNZ71990.1 - 0.027 14.6 0.1 0.045 13.9 0.1 1.4 1 0 0 1 1 1 0 Ankyrin ubiquitin-binding domain RRM_1 PF00076.22 KNZ71991.1 - 2.1e-10 40.3 1.1 6.4e-07 29.1 0.2 3.8 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 KNZ71992.1 - 4e-33 115.0 28.6 2.4e-31 109.1 28.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ71992.1 - 1.2e-06 27.7 44.0 1.3e-05 24.3 14.0 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily Pectinesterase PF01095.19 KNZ71993.1 - 1.7e-33 115.7 0.3 2.1e-33 115.3 0.3 1.1 1 0 0 1 1 1 1 Pectinesterase bZIP_1 PF00170.21 KNZ71995.1 - 3.7e-05 23.7 7.6 6.2e-05 23.0 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KNZ71995.1 - 0.0003 20.8 11.1 0.00053 20.0 11.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KNZ71995.1 - 0.014 15.9 3.2 0.026 15.1 3.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Suc_Fer-like PF06999.12 KNZ71996.1 - 9.5e-23 81.1 0.0 1.1e-22 80.9 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like TPR_12 PF13424.6 KNZ71999.1 - 2.9e-86 283.8 34.5 8.7e-12 45.2 0.1 9.8 2 1 9 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ71999.1 - 1.5e-80 263.2 0.4 4.4e-09 35.9 0.0 11.7 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ71999.1 - 3.7e-16 59.4 26.8 8.2e-06 25.4 2.2 5.0 1 1 2 4 4 4 3 MalT-like TPR region Patatin PF01734.22 KNZ71999.1 - 1.6e-12 48.1 0.0 3.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_17 PF13431.6 KNZ71999.1 - 3.8e-12 45.7 6.3 2.6 8.6 0.0 10.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ71999.1 - 7.2e-10 38.2 24.7 5.8 7.3 0.2 11.0 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ71999.1 - 7.2e-10 38.2 15.8 19 5.6 0.0 10.3 10 0 0 10 10 10 0 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ71999.1 - 1.2e-08 34.5 0.0 3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.6 KNZ71999.1 - 1.1e-07 32.4 3.8 11 6.8 0.0 7.9 6 3 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ71999.1 - 1.2e-05 25.1 13.9 0.94 9.9 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ71999.1 - 7.1e-05 23.1 1.3 1.1e+02 3.9 0.0 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ71999.1 - 0.00086 19.9 14.0 9.6 6.9 0.1 7.5 2 2 6 8 8 8 1 Domain of unknown function (DUF4404) TPR_1 PF00515.28 KNZ71999.1 - 0.0011 18.7 19.0 30 4.7 0.0 10.1 12 0 0 12 12 11 0 Tetratricopeptide repeat DUF4648 PF15505.6 KNZ71999.1 - 0.0027 18.5 0.2 1.1 10.1 0.0 4.6 5 1 1 6 6 5 1 Domain of unknown function (DUF4648) AAA_16 PF13191.6 KNZ71999.1 - 0.0029 18.0 0.0 0.022 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain IF-2B PF01008.17 KNZ71999.1 - 0.017 14.3 9.2 6.7 5.8 0.1 4.3 1 1 3 4 4 4 0 Initiation factor 2 subunit family ATPase_2 PF01637.18 KNZ71999.1 - 0.025 14.5 0.1 0.27 11.1 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea CbiA PF01656.23 KNZ71999.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-RVT PF13966.6 KNZ72000.1 - 0.0018 18.9 1.0 0.002 18.8 0.6 1.3 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase PBP_sp32 PF07222.12 KNZ72000.1 - 0.035 13.6 0.9 0.04 13.4 0.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-FPG_IleRS PF06827.14 KNZ72000.1 - 0.04 13.8 1.3 0.04 13.8 1.3 2.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Zn_Tnp_IS1595 PF12760.7 KNZ72000.1 - 0.35 10.9 9.8 1.4 8.9 9.8 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PIF1 PF05970.14 KNZ72001.1 - 4.1e-26 92.0 0.0 5.4e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ72001.1 - 0.0057 17.1 0.0 0.0085 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KNZ72001.1 - 0.06 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 KNZ72001.1 - 0.071 11.9 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.22 KNZ72001.1 - 0.084 13.3 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 KNZ72001.1 - 0.097 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ72001.1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain SH3_1 PF00018.28 KNZ72003.1 - 4.8e-13 48.5 0.0 7.2e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ72003.1 - 1.3e-10 40.9 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ72003.1 - 9.3e-09 34.8 0.0 1.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Sporozoite_P67 PF05642.11 KNZ72003.1 - 0.042 11.9 6.1 0.051 11.7 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_LMP1 PF05297.11 KNZ72003.1 - 0.17 11.1 1.2 0.29 10.3 1.2 1.4 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sugar_tr PF00083.24 KNZ72005.1 - 2.1e-103 346.6 12.2 4e-103 345.7 12.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ72005.1 - 5.5e-28 97.9 29.9 1.1e-27 96.9 18.9 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily AMP-binding PF00501.28 KNZ72006.1 - 4.7e-77 259.4 0.0 6.2e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ72006.1 - 7.5e-06 26.8 0.2 3.3e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF202 PF02656.15 KNZ72007.1 - 0.00012 22.4 5.3 0.00035 21.0 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) S_4TM PF18159.1 KNZ72007.1 - 0.46 9.7 1.4 0.53 9.5 1.0 1.3 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain CRPA PF05745.11 KNZ72007.1 - 2.8 7.9 5.7 5.4 7.0 5.7 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Gram_pos_anchor PF00746.21 KNZ72007.1 - 6.8 6.7 7.1 25 4.9 0.8 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Pectinesterase PF01095.19 KNZ72009.1 - 6.2e-38 130.2 6.2 7.8e-38 129.9 6.2 1.0 1 0 0 1 1 1 1 Pectinesterase DER1 PF04511.15 KNZ72010.1 - 1.2e-25 90.5 5.8 2.8e-23 82.8 5.8 2.0 1 1 0 1 1 1 1 Der1-like family Na_H_Exchanger PF00999.21 KNZ72011.1 - 4.4e-46 157.4 41.6 6.6e-46 156.8 41.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 KNZ72012.1 - 2.1e-51 174.9 49.1 2.8e-51 174.5 49.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_35 PF01301.19 KNZ72014.1 - 1.4e-76 258.2 0.0 1.9e-76 257.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KNZ72014.1 - 1.7e-58 196.1 2.0 2.8e-30 105.2 0.1 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KNZ72014.1 - 1.7e-34 119.2 0.6 3e-34 118.4 0.6 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KNZ72014.1 - 1.9e-20 72.2 0.1 6.3e-20 70.5 0.1 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 KNZ72014.1 - 0.039 13.3 0.2 0.26 10.6 0.2 2.0 1 1 0 1 1 1 0 Beta-galactosidase COX4 PF02936.14 KNZ72015.1 - 2.8e-38 131.0 0.3 4.5e-38 130.4 0.3 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV Ank_2 PF12796.7 KNZ72016.1 - 8.4e-08 32.7 0.2 0.00012 22.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ72016.1 - 0.00076 19.7 0.0 0.019 15.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ72016.1 - 0.0031 18.1 0.1 0.013 16.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RNA_pol_Rpb1_R PF05001.13 KNZ72016.1 - 1.3 9.5 4.5 4 8.0 4.5 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Ank_2 PF12796.7 KNZ72017.1 - 3.5e-14 53.2 1.2 8.8e-08 32.6 0.4 3.1 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ72017.1 - 9.3e-14 51.6 0.6 0.00024 21.6 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ72017.1 - 3.9e-10 39.8 0.7 0.0023 18.2 0.5 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ72017.1 - 1.4e-08 34.3 0.2 0.11 13.2 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KNZ72017.1 - 0.00029 21.2 0.1 25 5.6 0.0 4.6 3 1 1 4 4 4 2 Ankyrin repeat TPR_10 PF13374.6 KNZ72020.1 - 9.1e-12 44.5 1.4 9.6e-05 22.1 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72020.1 - 8.6e-10 38.8 0.6 1.1e-09 38.4 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72020.1 - 0.00071 19.8 0.1 0.16 12.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat HMD PF03201.16 KNZ72020.1 - 0.0093 16.2 0.1 0.011 15.9 0.1 1.1 1 0 0 1 1 1 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF4404 PF14357.6 KNZ72020.1 - 0.026 15.2 0.4 0.039 14.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) GLTP PF08718.11 KNZ72020.1 - 0.043 14.1 0.0 1.6 9.0 0.0 2.0 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) Steroid_dh PF02544.16 KNZ72021.1 - 1.9e-25 89.6 1.2 8.3e-16 58.3 0.1 2.6 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KNZ72021.1 - 1.9e-05 24.3 0.1 3.8e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) GMC_oxred_N PF00732.19 KNZ72022.1 - 2.2e-19 70.0 0.7 1.3e-18 67.5 0.2 2.0 2 0 0 2 2 2 1 GMC oxidoreductase zf-RING_2 PF13639.6 KNZ72022.1 - 1e-06 29.0 2.6 1e-06 29.0 2.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KNZ72022.1 - 2.7e-06 27.5 1.2 2.7e-06 27.5 1.2 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KNZ72022.1 - 4.5e-05 23.1 0.9 0.0031 17.2 0.2 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KNZ72022.1 - 0.00015 21.7 1.0 0.00015 21.7 1.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KNZ72022.1 - 0.00019 21.2 1.0 0.00019 21.2 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ72022.1 - 0.00025 20.8 6.7 0.00073 19.3 3.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KNZ72022.1 - 0.00031 20.3 0.5 0.00031 20.3 0.5 1.7 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KNZ72022.1 - 0.00035 20.5 0.6 0.0013 18.7 0.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 KNZ72022.1 - 0.0012 18.8 0.2 0.0024 17.9 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KNZ72022.1 - 0.0079 16.0 0.7 0.0079 16.0 0.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ72022.1 - 0.014 15.3 1.1 0.014 15.3 1.1 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KNZ72022.1 - 0.081 13.1 0.7 0.21 11.7 0.7 1.7 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KNZ72022.1 - 0.54 10.5 2.1 0.73 10.1 0.2 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KNZ72022.1 - 5.6 7.1 5.6 18 5.4 5.6 1.9 1 1 0 1 1 1 0 Zinc-finger Nop PF01798.18 KNZ72023.1 - 9.4e-85 283.7 0.5 2.3e-84 282.5 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KNZ72023.1 - 7.6e-21 74.3 0.7 7.6e-21 74.3 0.7 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain FRG1 PF06229.12 KNZ72023.1 - 0.0057 16.4 5.3 0.0097 15.6 5.3 1.4 1 0 0 1 1 1 1 FRG1-like domain SPT6_acidic PF14632.6 KNZ72023.1 - 0.42 11.2 16.3 3.9 8.1 13.9 3.0 2 1 1 3 3 3 0 Acidic N-terminal SPT6 UPF0223 PF05256.12 KNZ72024.1 - 0.063 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) PIF1 PF05970.14 KNZ72025.1 - 1.7e-49 168.9 0.0 2.2e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ72025.1 - 0.00027 20.7 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ72025.1 - 0.0012 19.2 0.0 0.0016 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ72025.1 - 0.0023 18.0 0.0 0.015 15.3 0.0 1.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ72025.1 - 0.017 14.8 0.2 0.043 13.6 0.2 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.8 KNZ72025.1 - 0.069 12.0 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.22 KNZ72025.1 - 0.099 13.0 0.1 0.51 10.7 0.1 2.1 1 1 0 1 1 1 0 RNA helicase IBN_N PF03810.19 KNZ72027.1 - 2.1e-08 34.0 0.0 2.7e-07 30.4 0.1 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KNZ72027.1 - 0.0053 16.8 0.4 0.065 13.3 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.10 KNZ72027.1 - 0.009 14.9 0.0 0.028 13.3 0.0 1.8 2 0 0 2 2 2 1 Cse1 HEAT PF02985.22 KNZ72027.1 - 0.052 13.8 0.0 0.68 10.4 0.1 3.1 3 0 0 3 3 3 0 HEAT repeat Actin PF00022.19 KNZ72028.1 - 8.4e-79 265.1 0.0 8e-78 261.8 0.0 1.9 1 1 0 1 1 1 1 Actin TANGO2 PF05742.12 KNZ72029.1 - 7.9e-39 134.2 0.0 1e-38 133.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Zn_clus PF00172.18 KNZ72030.1 - 1.3e-08 34.8 7.2 3e-08 33.7 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSS PF03034.15 KNZ72031.1 - 4e-113 377.7 10.0 5.1e-113 377.4 10.0 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase PET PF06297.14 KNZ72031.1 - 0.053 13.8 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 PET Domain MFS_1 PF07690.16 KNZ72033.1 - 6.7e-26 91.0 22.8 6.7e-26 91.0 22.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CopD PF05425.13 KNZ72033.1 - 0.12 12.7 5.3 0.14 12.6 0.1 2.9 2 0 0 2 2 2 0 Copper resistance protein D YTH PF04146.15 KNZ72034.1 - 2e-59 200.3 0.0 3.5e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 KNZ72034.1 - 8.1e-05 22.4 0.0 0.00065 19.5 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amino_oxidase PF01593.24 KNZ72035.1 - 5.6e-18 65.5 0.1 1.9e-15 57.2 0.0 2.5 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ72035.1 - 2.4e-15 56.5 0.0 1.3e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ72035.1 - 0.00076 19.2 0.2 0.0038 16.8 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ72035.1 - 0.0029 17.6 0.0 0.11 12.5 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KNZ72035.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 KNZ72035.1 - 0.12 11.1 0.0 0.47 9.1 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein gag-asp_proteas PF13975.6 KNZ72037.1 - 0.02 15.4 0.0 0.049 14.2 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF4880 PF16220.5 KNZ72037.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) DUF3168 PF11367.8 KNZ72038.1 - 0.09 13.0 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) Mem_trans PF03547.18 KNZ72039.1 - 6.2e-19 67.7 1.1 8.6e-19 67.2 1.1 1.1 1 0 0 1 1 1 1 Membrane transport protein RT_RNaseH PF17917.1 KNZ72040.1 - 2.1e-05 24.7 0.2 3.2e-05 24.2 0.1 1.3 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72040.1 - 6.8e-05 22.8 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Melibiase_2 PF16499.5 KNZ72043.1 - 7e-53 179.6 2.1 9.7e-41 139.8 0.1 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KNZ72043.1 - 1.4e-10 41.0 0.2 9e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KNZ72043.1 - 4e-06 26.0 0.1 8.9e-06 24.9 0.0 1.5 2 0 0 2 2 2 1 Melibiase PH PF00169.29 KNZ72044.1 - 0.14 12.7 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 PH domain MCD_N PF17408.2 KNZ72044.1 - 0.61 10.3 3.7 1.1 9.5 0.0 3.3 4 0 0 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain TACC_C PF05010.14 KNZ72044.1 - 1.3 8.7 10.7 0.064 13.0 2.1 2.6 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal 2OG-FeII_Oxy_2 PF13532.6 KNZ72045.1 - 1e-15 58.5 0.0 2.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-C2HC5 PF06221.13 KNZ72045.1 - 3.3 7.8 5.6 0.51 10.4 1.4 1.8 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type ATP-synt_DE_N PF02823.16 KNZ72046.1 - 2.5e-16 59.4 0.1 3.6e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain GCS PF03074.16 KNZ72047.1 - 1.9e-174 580.3 0.0 2.3e-174 580.0 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Nic96 PF04097.14 KNZ72050.1 - 9.2e-34 116.9 1.8 1.1e-33 116.6 1.8 1.0 1 0 0 1 1 1 1 Nup93/Nic96 MCM_N PF14551.6 KNZ72050.1 - 0.0031 18.1 0.2 2.3 8.9 0.0 2.3 2 0 0 2 2 2 2 MCM N-terminal domain SesA PF17107.5 KNZ72050.1 - 0.027 14.6 0.1 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases T2SSF PF00482.23 KNZ72050.1 - 0.093 12.7 0.4 0.48 10.4 0.0 2.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF3104 PF11302.8 KNZ72052.1 - 0.067 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) WD40 PF00400.32 KNZ72054.1 - 1.4e-06 28.9 0.4 0.025 15.4 0.0 4.1 3 1 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72054.1 - 3.1e-05 24.2 0.5 9.3 6.6 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KNZ72054.1 - 0.00017 22.0 0.2 2.5 8.7 0.0 4.8 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 KNZ72054.1 - 0.0023 17.5 0.1 0.077 12.6 0.0 2.9 2 1 1 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.6 KNZ72054.1 - 0.0034 17.4 0.4 5.9 7.0 0.0 3.7 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 KNZ72054.1 - 0.013 15.4 0.1 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat BBS1 PF14779.6 KNZ72054.1 - 0.031 13.7 0.4 2.7 7.4 0.0 3.1 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 1 Asp_protease PF09668.10 KNZ72055.1 - 0.06 13.1 0.1 9.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease rve PF00665.26 KNZ72056.1 - 1.3e-05 25.4 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 KNZ72056.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 KNZ72057.1 - 1.4e-07 31.7 0.0 2.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain YchF-GTPase_C PF06071.13 KNZ72058.1 - 1.2e-35 121.6 0.1 4.3e-35 119.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KNZ72058.1 - 5.8e-18 65.0 0.0 1.8e-17 63.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ72058.1 - 6.1e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 KNZ72058.1 - 0.042 12.8 0.2 0.35 9.8 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KNZ72058.1 - 0.12 12.9 0.0 0.6 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain Nop14 PF04147.12 KNZ72060.1 - 3.4 5.8 16.7 5.8 5.0 16.7 1.2 1 0 0 1 1 1 0 Nop14-like family MMtag PF10159.9 KNZ72062.1 - 1.2e-29 102.4 2.0 1.2e-29 102.4 2.0 3.3 3 0 0 3 3 3 1 Multiple myeloma tumor-associated F-box PF00646.33 KNZ72063.1 - 7.8e-07 28.8 9.2 0.00011 22.0 0.2 3.2 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 KNZ72063.1 - 0.0041 17.0 2.4 0.098 12.6 0.2 3.0 2 0 0 2 2 2 1 F-box-like MARVEL PF01284.23 KNZ72065.1 - 1.2e-07 31.9 8.1 4.1e-07 30.1 5.4 2.2 1 1 1 2 2 2 2 Membrane-associating domain Pro_isomerase PF00160.21 KNZ72067.1 - 6.5e-23 81.8 0.0 1.2e-22 80.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD rve PF00665.26 KNZ72067.1 - 3.4e-06 27.2 0.0 5.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain FAM60A PF15396.6 KNZ72067.1 - 0.0073 16.3 5.1 0.012 15.6 5.1 1.3 1 0 0 1 1 1 1 Protein Family FAM60A baeRF_family7 PF18849.1 KNZ72067.1 - 0.11 12.8 0.1 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 PIN_12 PF16289.5 KNZ72067.1 - 2.3 8.7 5.4 1.5 9.3 3.0 1.8 2 0 0 2 2 2 0 PIN domain VIR_N PF15912.5 KNZ72067.1 - 8.1 6.0 9.3 11 5.5 9.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal PhoPQ_related PF10142.9 KNZ72068.1 - 0.0004 19.2 0.1 0.00088 18.0 0.1 1.7 1 1 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_1 PF00561.20 KNZ72068.1 - 0.0019 17.9 0.0 0.18 11.4 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ72068.1 - 0.014 14.7 0.0 1.3 8.2 0.0 2.8 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KNZ72068.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DEAD PF00270.29 KNZ72069.1 - 4.4e-52 176.4 0.0 3.1e-51 173.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ72069.1 - 1.8e-32 112.0 0.0 5.6e-31 107.2 0.0 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ72069.1 - 4.7e-09 36.5 0.0 3.7e-08 33.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ72069.1 - 0.0018 18.0 0.0 0.048 13.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain UTP25 PF06862.12 KNZ72069.1 - 0.011 14.6 0.0 0.24 10.1 0.0 2.5 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 KNZ72069.1 - 0.022 15.1 0.0 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KNZ72069.1 - 0.17 12.3 0.1 19 5.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 KNZ72070.1 - 4.8e-40 136.8 0.0 6.7e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ72070.1 - 5.5e-15 55.7 0.0 1.1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KNZ72070.1 - 3e-05 24.0 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KNZ72070.1 - 0.0038 17.3 0.0 0.0057 16.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNZ72070.1 - 0.0077 15.8 0.0 1.3 8.5 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 KNZ72070.1 - 0.013 15.0 0.0 0.11 12.0 0.0 2.0 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_28 PF13521.6 KNZ72070.1 - 0.099 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain WSD PF15613.6 KNZ72071.1 - 0.25 11.8 0.0 0.25 11.8 0.0 3.5 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Methyltransf_25 PF13649.6 KNZ72072.1 - 7.2e-16 58.7 0.0 2.6e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ72072.1 - 1.2e-15 57.7 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ72072.1 - 3.4e-15 56.4 0.0 9.4e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ72072.1 - 3.4e-14 52.9 0.0 2e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ72072.1 - 1.9e-13 51.0 0.0 1.1e-12 48.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KNZ72072.1 - 6.1e-06 26.4 0.0 9.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KNZ72072.1 - 9.7e-05 21.9 0.0 0.00026 20.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.18 KNZ72072.1 - 0.00022 20.8 0.0 0.01 15.3 0.0 2.2 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 KNZ72072.1 - 0.0003 20.2 0.0 0.0031 16.9 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KNZ72072.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KNZ72072.1 - 0.003 17.0 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KNZ72072.1 - 0.0048 16.2 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain NodS PF05401.11 KNZ72072.1 - 0.01 15.5 0.0 0.02 14.5 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KNZ72072.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KNZ72072.1 - 0.061 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 KNZ72072.1 - 0.081 11.5 0.0 0.84 8.1 0.0 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 KNZ72072.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RRM_1 PF00076.22 KNZ72073.1 - 2.3e-14 52.9 0.1 3.8e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 KNZ72074.1 - 3.7e-28 98.3 0.1 4.5e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit HSV_VP16_C PF12149.8 KNZ72074.1 - 0.15 12.2 0.5 0.15 12.2 0.5 2.5 3 0 0 3 3 3 0 Herpes simplex virus virion protein 16 C terminal PI3Ka PF00613.20 KNZ72075.1 - 2.2e-53 180.4 0.1 3.4e-53 179.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KNZ72075.1 - 3.7e-43 148.1 0.0 4.2e-27 95.5 0.0 3.0 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KNZ72075.1 - 1.9e-40 138.0 0.0 3.6e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 KNZ72075.1 - 0.065 12.5 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Lig_C PF18330.1 KNZ72075.1 - 0.12 12.4 0.0 0.65 10.0 0.2 2.0 2 0 0 2 2 2 0 Ligase Pab1020 C-terminal region Vps26 PF03643.15 KNZ72077.1 - 4.1e-10 39.1 0.0 9.7e-10 37.9 0.0 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 26 DASH_Dad2 PF08654.10 KNZ72078.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 gag-asp_proteas PF13975.6 KNZ72080.1 - 0.0006 20.3 0.0 0.0018 18.8 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ72080.1 - 0.0033 18.0 0.0 0.01 16.4 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease Vps26 PF03643.15 KNZ72081.1 - 8.1e-38 130.0 0.2 2.2e-29 102.3 0.0 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 Retrotran_gag_2 PF14223.6 KNZ72082.1 - 4.9e-10 39.2 0.3 6.5e-10 38.8 0.3 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ72082.1 - 0.013 15.2 0.2 0.025 14.3 0.2 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger RNase_H PF00075.24 KNZ72083.1 - 9e-05 22.7 0.0 9e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 RNase H Retrotran_gag_2 PF14223.6 KNZ72084.1 - 5.1e-15 55.4 0.2 7.6e-15 54.8 0.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ72084.1 - 6.4e-05 22.6 0.6 0.00015 21.4 0.6 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger TolA_bind_tri PF16331.5 KNZ72084.1 - 0.043 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 TolA binding protein trimerisation ZapA PF05164.13 KNZ72084.1 - 0.058 13.8 1.9 0.16 12.4 1.9 1.9 1 1 0 1 1 1 0 Cell division protein ZapA Herpes_V23 PF01802.17 KNZ72084.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein NAPRTase_N PF17767.1 KNZ72084.1 - 0.16 12.3 1.1 0.48 10.8 0.0 2.1 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain zf-C3HC PF07967.13 KNZ72084.1 - 0.44 10.6 3.8 0.42 10.6 0.2 2.3 2 1 0 2 2 2 0 C3HC zinc finger-like BNIP2 PF12496.8 KNZ72085.1 - 0.047 14.1 1.5 0.063 13.7 1.5 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Vps26 PF03643.15 KNZ72086.1 - 3.6e-119 396.8 3.0 4.3e-119 396.6 3.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KNZ72086.1 - 0.0062 16.6 0.7 0.35 10.9 0.3 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Complex1_51K PF01512.17 KNZ72087.1 - 2.1e-48 164.0 0.0 3.7e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KNZ72087.1 - 1.1e-30 105.5 1.0 1.8e-30 104.8 0.1 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KNZ72087.1 - 9.3e-09 35.0 0.0 2.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 KNZ72087.1 - 0.08 13.0 0.5 0.15 12.2 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF1192 PF06698.11 KNZ72088.1 - 0.027 14.5 0.4 0.087 12.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FAD-oxidase_C PF02913.19 KNZ72089.1 - 4.9e-57 193.4 0.0 8.7e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KNZ72089.1 - 7e-29 100.3 0.0 1.4e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain eIF3_N PF09440.10 KNZ72090.1 - 5.6e-45 153.0 4.0 1.8e-44 151.4 4.0 1.8 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KNZ72090.1 - 1e-08 35.6 0.1 3.7e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 PCI domain PBECR3 PF18812.1 KNZ72090.1 - 0.098 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Cpn60_TCP1 PF00118.24 KNZ72091.1 - 5.3e-168 559.7 2.5 6.1e-168 559.5 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF627 PF04781.12 KNZ72091.1 - 0.015 15.3 0.0 0.075 13.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Ribosomal_L4 PF00573.22 KNZ72092.1 - 7.7e-40 136.6 1.4 1.3e-39 135.9 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KNZ72092.1 - 1.5e-29 101.9 3.6 1.9e-29 101.5 0.8 2.2 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain RT_RNaseH PF17917.1 KNZ72094.1 - 3.2e-08 33.8 0.0 6.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72094.1 - 9.7e-05 22.3 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase zf-ZPR1 PF03367.13 KNZ72095.1 - 2.1e-104 346.2 0.0 1.1e-50 171.6 0.0 3.0 2 1 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 KNZ72095.1 - 0.0069 16.4 0.6 0.45 10.5 0.1 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2688 PF10892.8 KNZ72095.1 - 0.0099 15.3 1.6 0.66 9.5 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2688) Zn-ribbon_8 PF09723.10 KNZ72095.1 - 0.01 15.9 1.9 3.3 7.9 0.1 2.9 2 1 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KNZ72095.1 - 0.014 15.4 0.8 0.25 11.4 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KNZ72095.1 - 0.1 12.0 6.7 0.4 10.2 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 KNZ72095.1 - 0.18 11.6 8.0 2.7 7.8 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KNZ72095.1 - 0.18 11.8 0.7 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbons Gal4_dimer PF03902.13 KNZ72095.1 - 0.29 11.3 1.1 18 5.6 0.5 3.4 3 1 0 3 3 2 0 Gal4-like dimerisation domain Ribosomal_L37e PF01907.19 KNZ72095.1 - 0.55 10.4 3.3 16 5.7 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L37e Rubredoxin_2 PF18073.1 KNZ72095.1 - 0.6 9.9 9.6 3.8 7.3 0.3 3.3 3 0 0 3 3 3 0 Rubredoxin metal binding domain DUF983 PF06170.12 KNZ72095.1 - 0.81 10.1 2.8 1.1e+02 3.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Nudix_N_2 PF14803.6 KNZ72095.1 - 2.9 7.9 7.4 1.4 8.9 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.11 KNZ72095.1 - 2.9 7.9 6.1 25 4.9 0.3 3.2 2 1 1 3 3 3 0 Putative transposase DNA-binding domain ABC_membrane PF00664.23 KNZ72096.1 - 3.9e-40 138.2 11.0 4.9e-40 137.9 11.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ72096.1 - 2.5e-08 34.5 0.0 8.8e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KNZ72096.1 - 0.00016 21.2 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Sec34 PF04136.15 KNZ72097.1 - 1.5e-45 154.8 0.0 3.9e-45 153.4 0.0 1.8 1 0 0 1 1 1 1 Sec34-like family zf-H2C2_2 PF13465.6 KNZ72098.1 - 3e-09 36.9 13.6 1.8e-07 31.2 0.4 4.2 4 0 0 4 4 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KNZ72098.1 - 1.6e-07 31.4 12.2 0.001 19.4 4.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ72098.1 - 0.00061 20.4 11.1 0.0051 17.5 3.2 3.8 4 0 0 4 4 2 2 C2H2-type zinc finger zf-met PF12874.7 KNZ72098.1 - 0.0008 19.7 2.4 0.0014 18.9 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KNZ72098.1 - 0.0065 16.4 6.5 0.61 10.2 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 KNZ72098.1 - 0.017 15.3 12.2 0.036 14.2 12.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 KNZ72098.1 - 0.062 13.6 1.0 1.1 9.7 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNZ72098.1 - 0.089 13.1 5.1 0.59 10.5 0.5 2.5 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 KNZ72098.1 - 0.092 12.4 1.7 0.15 11.8 0.2 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_9 PF16293.5 KNZ72098.1 - 0.39 10.6 2.0 0.97 9.3 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 KNZ72098.1 - 3.8 8.2 7.9 0.82 10.4 3.4 2.2 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 KNZ72098.1 - 4.9 7.5 11.9 0.29 11.5 5.7 2.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Retrotran_gag_2 PF14223.6 KNZ72099.1 - 1.7e-11 43.9 0.0 2.1e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Glyco_hydro_79C PF16862.5 KNZ72100.1 - 1.1e-14 55.2 0.1 2e-14 54.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF572 PF04502.13 KNZ72101.1 - 5.2e-67 226.8 0.5 6.2e-67 226.6 0.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Rep_fac-A_3 PF08661.11 KNZ72101.1 - 0.12 12.8 0.3 16 5.9 0.0 2.6 2 1 1 3 3 3 0 Replication factor A protein 3 ARID PF01388.21 KNZ72102.1 - 1.4e-13 51.3 0.0 4.9e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Fmp27_WPPW PF10359.9 KNZ72102.1 - 7.6 5.3 9.2 0.11 11.3 0.6 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain SNARE_assoc PF09335.11 KNZ72103.1 - 8.6e-12 45.6 6.7 1.4e-11 44.9 5.4 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein NAPRTase PF04095.16 KNZ72105.1 - 4e-64 216.5 0.1 5.5e-64 216.1 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KNZ72105.1 - 2.3e-35 121.7 0.1 3.8e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNase_PH PF01138.21 KNZ72106.1 - 1.1e-34 119.8 0.3 2.4e-34 118.7 0.1 1.7 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KNZ72106.1 - 1.3e-05 25.1 0.1 3.7e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Methyltransf_4 PF02390.17 KNZ72107.1 - 1.4e-42 145.1 0.0 1.8e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Citrate_synt PF00285.21 KNZ72108.1 - 9.3e-78 261.8 0.0 1.5e-62 211.7 0.0 2.1 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Eclosion PF04736.12 KNZ72108.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone PLDc_2 PF13091.6 KNZ72109.1 - 2e-12 47.1 0.0 2.4e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KNZ72109.1 - 5.5e-10 39.0 0.1 0.00047 20.2 0.2 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif Actin PF00022.19 KNZ72110.1 - 7.7e-87 291.5 0.0 4.1e-85 285.9 0.0 2.0 1 1 0 1 1 1 1 Actin U1snRNP70_N PF12220.8 KNZ72111.1 - 3.9e-05 24.2 2.5 5.7e-05 23.7 2.5 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal UbiA PF01040.18 KNZ72112.1 - 5.6e-57 192.9 21.6 5.6e-57 192.9 21.6 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family Tmemb_14 PF03647.13 KNZ72112.1 - 0.089 13.5 0.1 0.089 13.5 0.1 2.9 3 0 0 3 3 3 0 Transmembrane proteins 14C Homeodomain PF00046.29 KNZ72113.1 - 2.7e-18 65.5 5.9 7e-18 64.2 5.9 1.7 1 0 0 1 1 1 1 Homeodomain zf-Tim10_DDP PF02953.15 KNZ72114.1 - 2.4e-24 84.8 1.0 2.8e-24 84.5 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DnaJ PF00226.31 KNZ72115.1 - 7.6e-21 74.0 0.4 1.8e-20 72.8 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KNZ72115.1 - 3.5e-10 39.9 0.3 7.9e-10 38.8 0.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ72115.1 - 4.4e-09 36.4 0.6 1.1e-08 35.2 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KNZ72115.1 - 0.0084 16.4 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 KNZ72115.1 - 0.012 15.5 0.3 5.5 7.0 0.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger SAGA-Tad1 PF12767.7 KNZ72115.1 - 0.91 9.2 11.1 0.35 10.6 0.6 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Prp18 PF02840.15 KNZ72116.1 - 1.8e-61 206.4 0.1 1.8e-61 206.4 0.1 2.3 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 KNZ72116.1 - 8.8e-12 44.4 5.3 1.8e-11 43.4 5.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pinin_SDK_memA PF04696.13 KNZ72116.1 - 4.3 7.4 18.9 7.8 6.6 12.1 2.8 2 1 0 2 2 2 0 pinin/SDK/memA/ protein conserved region COX6B PF02297.17 KNZ72117.1 - 1.5e-19 69.9 6.1 1.7e-19 69.8 6.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 KNZ72117.1 - 0.0061 16.7 2.9 0.01 15.9 2.9 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KNZ72117.1 - 0.031 14.3 2.0 0.05 13.6 2.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Oxidored_molyb PF00174.19 KNZ72118.1 - 9.2e-59 197.9 0.0 1.3e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KNZ72118.1 - 5.9e-16 58.7 1.1 1.2e-15 57.7 1.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 KNZ72118.1 - 0.039 13.9 1.1 0.14 12.2 1.1 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat DUF1748 PF08520.10 KNZ72119.1 - 3.3e-24 84.5 0.0 3.7e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) HTH_AraC PF00165.23 KNZ72119.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family Glyco_hydro_18 PF00704.28 KNZ72120.1 - 2.1e-18 67.1 0.2 2.8e-18 66.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KNZ72120.1 - 0.004 17.7 3.1 0.02 15.4 3.1 2.3 1 0 0 1 1 1 1 Carbohydrate binding domain Mucin PF01456.17 KNZ72120.1 - 0.33 11.0 22.8 0.65 10.0 22.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Fungal_trans PF04082.18 KNZ72121.1 - 3.6e-07 29.5 0.0 6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Adaptin_N PF01602.20 KNZ72122.1 - 3.1e-119 398.9 0.6 4.7e-119 398.3 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KNZ72122.1 - 7.7e-14 52.0 0.3 6e-12 45.9 0.0 3.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ72122.1 - 4.1e-06 27.1 0.5 0.0057 17.0 0.0 3.6 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 KNZ72122.1 - 0.015 15.8 0.1 7.7 7.1 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 KNZ72122.1 - 0.019 15.2 4.0 2.8 8.4 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat Myc_N PF01056.18 KNZ72122.1 - 0.021 14.7 1.2 0.035 14.0 1.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region SGT1 PF07093.11 KNZ72122.1 - 2.5 6.4 7.6 4.1 5.7 7.6 1.2 1 0 0 1 1 1 0 SGT1 protein CobT PF06213.12 KNZ72122.1 - 6.7 6.0 16.3 11 5.3 16.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RVT_2 PF07727.14 KNZ72123.1 - 0.036 13.7 0.2 0.092 12.4 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Frag1 PF10277.9 KNZ72124.1 - 1.7e-38 132.4 10.6 1.7e-38 132.4 10.6 2.4 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family cobW PF02492.19 KNZ72125.1 - 2.7e-39 134.6 0.0 3.5e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KNZ72125.1 - 0.006 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KNZ72125.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1574 PF07611.11 KNZ72125.1 - 0.06 12.7 0.0 0.096 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1574) AAA_16 PF13191.6 KNZ72125.1 - 0.079 13.3 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.12 KNZ72125.1 - 0.16 11.4 0.0 0.4 10.1 0.0 1.6 2 0 0 2 2 2 0 Poxvirus A32 protein DnaJ PF00226.31 KNZ72126.1 - 1.4e-17 63.6 0.2 4.3e-17 62.0 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_79C PF16862.5 KNZ72127.1 - 1.5e-18 67.6 0.6 2.9e-18 66.6 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Serinc PF03348.15 KNZ72128.1 - 2.9e-144 481.2 8.4 3.5e-144 480.9 8.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Acetyltransf_13 PF13880.6 KNZ72129.1 - 6.2e-15 54.9 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 KNZ72129.1 - 6.7e-11 41.8 0.2 1.1e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 KNZ72129.1 - 0.013 16.0 0.0 0.13 12.7 0.0 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ72129.1 - 0.023 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nudix_N_2 PF14803.6 KNZ72129.1 - 0.98 9.4 3.3 0.91 9.5 1.5 1.9 2 0 0 2 2 2 0 Nudix N-terminal Rad51 PF08423.11 KNZ72130.1 - 3.7e-08 33.0 0.0 4.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KNZ72130.1 - 2.8e-05 23.7 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KNZ72130.1 - 0.00088 18.7 0.2 0.0017 17.7 0.2 1.8 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KNZ72130.1 - 0.0051 16.4 0.1 0.014 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KNZ72130.1 - 0.0071 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain CobU PF02283.16 KNZ72130.1 - 0.0077 15.8 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 2 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_22 PF13401.6 KNZ72130.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 KNZ72130.1 - 0.065 12.6 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 KNZ72130.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea gag-asp_proteas PF13975.6 KNZ72131.1 - 0.002 18.7 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CRIM PF16978.5 KNZ72132.1 - 0.11 12.7 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain DUF908 PF06012.12 KNZ72133.1 - 0.2 11.0 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Retrotran_gag_2 PF14223.6 KNZ72134.1 - 0.001 18.8 0.2 0.0016 18.1 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2202 PF09968.9 KNZ72134.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) RINGv PF12906.7 KNZ72134.1 - 0.071 13.3 0.1 0.25 11.5 0.1 1.9 1 0 0 1 1 1 0 RING-variant domain V-set_2 PF15910.5 KNZ72135.1 - 0.03 14.4 0.3 0.067 13.3 0.0 1.6 2 0 0 2 2 2 0 ICOS V-set domain DUF1356 PF07092.12 KNZ72135.1 - 0.051 12.8 0.7 0.067 12.5 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) eIF3g PF12353.8 KNZ72135.1 - 0.077 13.4 4.2 0.077 13.4 0.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Cytochrom_c3_2 PF14537.6 KNZ72135.1 - 2.9 8.4 11.8 1.7 9.1 4.7 2.2 1 1 1 2 2 2 0 Cytochrome c3 DnaJ_CXXCXGXG PF00684.19 KNZ72135.1 - 3.1 8.2 11.8 22 5.5 0.7 2.3 1 1 1 2 2 2 0 DnaJ central domain gag-asp_proteas PF13975.6 KNZ72139.1 - 0.0027 18.2 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ72139.1 - 0.016 15.9 0.0 0.029 15.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 KNZ72140.1 - 7e-07 29.5 0.0 4.7e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72140.1 - 0.0043 17.1 0.0 0.047 13.7 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KNZ72141.1 - 7.5e-06 26.1 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF1643 PF07799.12 KNZ72141.1 - 0.024 14.8 0.6 0.92 9.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1643) rve_3 PF13683.6 KNZ72141.1 - 0.036 13.9 0.0 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain Plavaka PF18759.1 KNZ72143.1 - 9e-09 35.0 0.1 1e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 Plavaka transposase DHDPS PF00701.22 KNZ72144.1 - 1.9e-43 148.3 0.0 2.2e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Dynamin_N PF00350.23 KNZ72145.1 - 3.1e-43 147.7 0.0 9.2e-43 146.2 0.0 1.9 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KNZ72145.1 - 1.1e-09 37.9 0.0 2.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KNZ72145.1 - 1.9e-05 24.7 0.0 0.00017 21.7 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KNZ72145.1 - 0.028 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ72145.1 - 0.064 13.0 0.6 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Spectrin PF00435.21 KNZ72145.1 - 0.13 12.8 2.2 0.38 11.3 0.4 2.6 2 0 0 2 2 2 0 Spectrin repeat FeoB_N PF02421.18 KNZ72145.1 - 0.16 11.5 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SCP2 PF02036.17 KNZ72146.1 - 4.3e-26 91.4 1.8 5e-26 91.1 1.8 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KNZ72146.1 - 4.8e-06 26.9 1.5 5.9e-06 26.6 1.5 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KNZ72146.1 - 0.0056 17.0 0.1 0.0074 16.7 0.1 1.3 1 0 0 1 1 1 1 Sterol carrier protein domain Big_6 PF17936.1 KNZ72146.1 - 0.023 15.0 0.7 0.087 13.1 0.3 2.1 1 1 1 2 2 2 0 Bacterial Ig domain DUF5024 PF16427.5 KNZ72146.1 - 0.039 14.3 0.1 0.068 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) Maf1 PF09174.10 KNZ72147.1 - 5.2e-42 144.0 1.7 2.2e-35 122.3 0.0 2.6 3 0 0 3 3 3 2 Maf1 regulator TPR_2 PF07719.17 KNZ72148.1 - 5.3e-29 98.0 8.8 6.6e-06 25.9 0.1 8.8 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ72148.1 - 2.8e-27 93.4 1.3 2.6e-08 33.3 0.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ72148.1 - 1.7e-24 85.8 5.2 3.4e-17 62.4 0.0 5.3 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KNZ72148.1 - 8.1e-19 66.2 1.2 5.7e-07 29.3 0.1 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72148.1 - 1.6e-17 63.5 11.7 1.3e-09 38.2 0.6 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ72148.1 - 7e-12 45.7 5.9 0.011 16.2 0.2 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ72148.1 - 1e-11 45.2 0.9 0.00091 19.8 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ72148.1 - 1.4e-10 40.7 2.4 0.00011 21.8 0.0 6.3 8 1 0 8 8 8 2 TPR repeat TPR_10 PF13374.6 KNZ72148.1 - 7.8e-10 38.3 3.3 0.037 13.9 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72148.1 - 9.7e-10 37.8 10.6 0.017 15.1 0.1 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ72148.1 - 1.1e-08 35.2 11.9 0.0021 18.6 0.1 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72148.1 - 2.7e-08 33.6 4.1 0.98 10.0 0.1 7.3 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ72148.1 - 1.2e-07 31.4 0.5 3.7e-05 23.3 0.2 2.7 2 0 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 KNZ72148.1 - 4.1e-07 30.3 7.1 8.4 7.5 0.0 8.2 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72148.1 - 0.00055 20.0 0.5 1.5 9.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.6 KNZ72148.1 - 0.0019 17.7 0.1 0.064 12.7 0.2 2.8 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 KNZ72148.1 - 0.066 13.2 11.7 4.6 7.3 0.0 6.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ72148.1 - 0.2 12.4 2.2 62 4.7 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat SHP PF03579.13 KNZ72149.1 - 0.0054 16.7 0.5 0.0054 16.7 0.5 2.0 2 0 0 2 2 2 1 Small hydrophobic protein Spectrin PF00435.21 KNZ72149.1 - 0.14 12.7 0.2 0.28 11.7 0.2 1.4 1 0 0 1 1 1 0 Spectrin repeat Pkinase PF00069.25 KNZ72150.1 - 1.5e-61 208.0 0.0 2.1e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72150.1 - 4e-32 111.5 0.0 5.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ72150.1 - 1.9e-08 34.0 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ72150.1 - 1.2e-05 24.3 0.1 2e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ72150.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Macro PF01661.21 KNZ72151.1 - 1.6e-29 102.3 0.0 2.6e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Macro domain Sugar_tr PF00083.24 KNZ72152.1 - 6.8e-101 338.3 19.5 1.5e-99 333.9 19.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ72152.1 - 5.7e-22 78.1 21.6 5.7e-22 78.1 21.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 KNZ72152.1 - 0.0021 17.0 1.0 0.0038 16.2 0.1 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM PhoR PF11808.8 KNZ72152.1 - 0.1 13.0 3.7 1.3 9.5 0.0 3.5 2 1 0 3 3 3 0 Phosphate regulon sensor protein PhoR Ank_2 PF12796.7 KNZ72153.1 - 4.6e-05 23.9 0.0 0.00097 19.7 0.0 2.3 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ72153.1 - 0.00055 20.2 0.1 1.5 9.7 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 KNZ72153.1 - 0.042 14.4 0.1 3 8.5 0.1 2.6 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ72153.1 - 0.18 12.2 0.2 21 5.6 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeats (many copies) RDM PF11002.8 KNZ72154.1 - 0.016 15.2 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 RFPL defining motif (RDM) RRM_1 PF00076.22 KNZ72155.1 - 4.6e-15 55.2 0.0 9.7e-15 54.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 KNZ72155.1 - 0.035 13.7 0.2 4.6 6.9 0.0 2.7 2 0 0 2 2 2 0 Sporulation protein family 7 Sugar_tr PF00083.24 KNZ72156.1 - 4.2e-52 177.5 17.3 1.5e-31 109.8 4.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ72156.1 - 2.2e-19 69.6 26.1 2.2e-19 69.6 26.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.15 KNZ72157.1 - 6.9e-11 42.0 0.8 6.9e-11 42.0 0.8 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KNZ72157.1 - 0.00077 20.2 1.3 0.0011 19.7 1.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like eIF-1a PF01176.19 KNZ72158.1 - 4e-22 77.8 0.0 5.7e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 NPR3 PF03666.13 KNZ72160.1 - 7.2e-94 315.2 1.2 1.1e-91 307.9 1.2 2.3 1 1 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 KNZ72160.1 - 0.084 11.6 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Nitrogen permease regulator 2 AvrL567-A PF11529.8 KNZ72160.1 - 0.09 13.0 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Melampsora lini avirulence protein AvrL567-A Torus PF16131.5 KNZ72161.1 - 8.1e-29 100.5 3.6 1.7e-28 99.5 3.6 1.5 1 0 0 1 1 1 1 Torus domain Nup35_RRM_2 PF14605.6 KNZ72161.1 - 3.7e-05 23.6 0.3 8.7e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KNZ72161.1 - 0.00013 21.7 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DFRP_C PF16543.5 KNZ72162.1 - 1.4e-31 108.8 1.4 1.4e-31 108.8 1.4 3.7 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KNZ72162.1 - 7.2e-08 33.1 11.3 1.9e-05 25.3 3.6 3.6 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KNZ72162.1 - 1.5e-05 24.8 1.0 1.5e-05 24.8 1.0 2.5 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KNZ72162.1 - 1.5e-05 24.7 12.1 0.00036 20.3 3.1 3.2 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KNZ72162.1 - 3.2e-05 23.8 21.0 0.00013 21.9 7.2 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KNZ72162.1 - 0.0027 18.1 8.6 0.55 10.8 4.6 2.5 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KNZ72162.1 - 0.019 15.2 4.0 1.1 9.5 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger containing family Ndc1_Nup PF09531.10 KNZ72162.1 - 0.14 10.8 0.8 0.17 10.5 0.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR_4 PF12799.7 KNZ72164.1 - 6.2e-23 80.5 34.4 1.2e-07 31.9 2.6 8.7 6 2 2 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ72164.1 - 5.8e-20 70.8 33.1 7.9e-10 38.4 4.3 8.4 6 2 2 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 KNZ72164.1 - 1.3e-15 56.1 17.7 0.42 10.8 0.0 10.6 11 0 0 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.33 KNZ72164.1 - 4.3e-11 41.8 19.1 2.5 9.0 0.0 10.0 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 KNZ72164.1 - 0.014 14.9 7.2 0.34 10.4 1.7 3.9 5 0 0 5 5 5 0 Leucine-rich repeat LRR_2 PF07723.13 KNZ72164.1 - 1.2 9.9 5.0 1e+02 3.8 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat zf-Di19 PF05605.12 KNZ72165.1 - 0.09 13.1 1.8 2 8.8 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.21 KNZ72165.1 - 0.097 12.8 3.3 0.19 11.9 3.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C2H2_4 PF13894.6 KNZ72165.1 - 0.22 12.5 0.3 0.22 12.5 0.3 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 KNZ72165.1 - 0.31 11.5 0.8 0.82 10.2 0.0 2.1 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2 PF00096.26 KNZ72165.1 - 0.66 10.5 9.0 2.6 8.7 0.3 3.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.6 KNZ72167.1 - 0.12 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MAP70 PF07058.11 KNZ72167.1 - 0.86 8.3 5.8 1.2 7.8 5.8 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 CCDC106 PF15794.5 KNZ72167.1 - 6.3 6.4 10.2 14 5.3 10.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF2684 PF10885.8 KNZ72168.1 - 0.085 13.0 1.6 0.5 10.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2684) zf-C2H2 PF00096.26 KNZ72169.1 - 1.5e-12 47.2 12.2 0.00015 22.1 0.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ72169.1 - 1.5e-08 34.7 16.3 0.00014 22.1 0.4 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ72169.1 - 2.7e-07 30.8 14.2 0.04 14.8 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KNZ72169.1 - 0.0066 16.6 5.9 4.6 7.3 0.1 3.1 1 1 2 3 3 3 3 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KNZ72169.1 - 0.014 15.4 2.6 0.16 12.0 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KNZ72169.1 - 0.016 15.5 3.5 0.049 13.9 2.9 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KNZ72169.1 - 2.6 8.7 11.9 5.3 7.7 5.4 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 KNZ72169.1 - 3 7.7 7.9 0.85 9.4 0.1 3.0 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KNZ72169.1 - 3.1 8.2 8.6 3.6 8.0 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 KNZ72169.1 - 3.8 7.7 7.3 2.8 8.1 0.7 2.8 1 1 3 4 4 4 0 Zinc ribbon domain Thymidylat_synt PF00303.19 KNZ72170.1 - 1.5e-106 355.4 0.0 1.7e-106 355.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF1295 PF06966.12 KNZ72171.1 - 2.9e-32 112.1 15.4 1.8e-31 109.5 10.9 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) ICMT PF04140.14 KNZ72171.1 - 0.015 15.7 0.1 0.053 14.0 0.1 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sde2_N_Ubi PF13019.6 KNZ72173.1 - 1.6e-31 109.4 3.9 5.8e-30 104.3 3.9 2.4 1 1 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain HMGL-like PF00682.19 KNZ72174.1 - 2.8e-77 259.9 0.4 3.9e-77 259.4 0.4 1.2 1 0 0 1 1 1 1 HMGL-like Response_reg PF00072.24 KNZ72175.1 - 5.6e-20 71.6 0.0 5.7e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 KNZ72175.1 - 3.7e-16 59.6 0.0 1e-15 58.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KNZ72175.1 - 4.6e-13 49.0 0.1 1.3e-12 47.5 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain UDG PF03167.19 KNZ72176.1 - 3.5e-11 43.3 0.0 6.5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily bZIP_1 PF00170.21 KNZ72177.1 - 0.00045 20.3 1.6 0.00076 19.5 1.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KNZ72177.1 - 0.0029 17.7 1.0 0.0053 16.8 1.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper ERCC3_RAD25_C PF16203.5 KNZ72178.1 - 5e-123 409.1 0.1 1.1e-122 408.0 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KNZ72178.1 - 7.1e-38 129.6 0.1 1.7e-37 128.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ72178.1 - 5.2e-16 59.1 0.0 1e-15 58.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNZ72178.1 - 1.9e-10 41.1 0.0 6.6e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KNZ72178.1 - 2.8e-09 36.2 0.1 4e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SF1-HH PF16275.5 KNZ72179.1 - 7.2e-40 135.9 0.9 1.6e-39 134.7 0.9 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 KNZ72179.1 - 1.1e-11 44.2 8.9 1.4e-05 24.9 0.3 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ72179.1 - 1e-06 28.6 3.7 0.0025 17.7 1.4 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.29 KNZ72179.1 - 8e-06 25.6 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.6 KNZ72179.1 - 0.0038 17.0 6.3 0.54 10.1 0.9 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 KNZ72179.1 - 0.0057 16.4 7.1 0.41 10.4 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle CCDC-167 PF15188.6 KNZ72179.1 - 0.008 16.5 2.4 3.7 7.9 0.1 2.4 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 167 Prim_Zn_Ribbon PF08273.12 KNZ72179.1 - 0.23 11.8 3.6 0.56 10.5 3.6 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase DnaJ_CXXCXGXG PF00684.19 KNZ72179.1 - 0.23 11.8 4.8 0.46 10.9 4.8 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.6 KNZ72179.1 - 3.6 7.5 9.8 0.36 10.7 0.7 2.5 2 0 0 2 2 2 0 Zinc knuckle Methyltr_RsmB-F PF01189.17 KNZ72180.1 - 6.8e-28 97.7 0.0 1.1e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 KNZ72180.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DnaJ_C PF01556.18 KNZ72181.1 - 5.3e-37 127.2 0.1 7.2e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 KNZ72181.1 - 2.1e-10 40.8 18.2 3.6e-10 40.1 18.2 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.31 KNZ72181.1 - 3.1e-09 36.8 0.3 6.1e-09 35.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Cytochrome_C7 PF14522.6 KNZ72181.1 - 0.015 15.3 5.8 0.2 11.7 0.9 2.3 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 KNZ72181.1 - 0.025 15.1 6.4 0.062 13.8 1.8 2.3 2 0 0 2 2 2 0 Cytochrome c3 HypA PF01155.19 KNZ72181.1 - 0.13 12.3 11.7 2.3 8.3 0.5 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 KNZ72181.1 - 1.3 9.0 16.8 3.9 7.5 4.4 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 KNZ72181.1 - 2.3 8.3 8.9 11 6.2 1.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon RseC_MucC PF04246.12 KNZ72181.1 - 2.7 7.9 6.3 14 5.6 0.4 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ThuA PF06283.11 KNZ72182.1 - 1.1e-63 215.3 0.0 1.4e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Trehalose utilisation RNase_PH PF01138.21 KNZ72182.1 - 0.056 13.9 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 ECH_1 PF00378.20 KNZ72184.1 - 2.7e-17 62.9 0.0 1.1e-16 61.0 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ72184.1 - 5.1e-06 26.2 0.0 7.6e-06 25.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 KNZ72184.1 - 0.045 12.4 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain Asp PF00026.23 KNZ72185.1 - 1.4e-65 221.8 4.0 1.7e-65 221.5 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ72185.1 - 2.3e-09 37.8 3.0 2.1e-08 34.6 0.7 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Cys_Met_Meta_PP PF01053.20 KNZ72187.1 - 1.2e-128 429.0 0.0 1.4e-128 428.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 KNZ72187.1 - 4.6e-15 55.6 0.0 2.3e-14 53.4 0.0 2.3 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KNZ72187.1 - 2.4e-05 24.6 0.1 8.8e-05 22.8 0.0 2.0 1 1 1 2 2 2 1 GHMP kinases C terminal Aminotran_1_2 PF00155.21 KNZ72187.1 - 0.00014 21.2 0.0 0.00023 20.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GalKase_gal_bdg PF10509.9 KNZ72187.1 - 0.00019 20.9 0.1 0.0004 19.9 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.11 KNZ72187.1 - 0.00036 19.2 0.1 0.12 10.9 0.0 2.1 2 0 0 2 2 2 2 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 KNZ72187.1 - 0.00057 19.3 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KNZ72187.1 - 0.045 13.0 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 Beta-eliminating lyase SelA PF03841.13 KNZ72187.1 - 0.17 10.9 0.0 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase Terpene_synth_C PF03936.16 KNZ72188.1 - 4.8e-05 22.8 0.0 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RNA_pol_Rpb5_C PF01191.19 KNZ72189.1 - 2.7e-31 107.2 0.1 5.2e-31 106.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KNZ72189.1 - 1.4e-26 92.9 0.0 2.5e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 KNZ72189.1 - 0.00075 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease WD40 PF00400.32 KNZ72190.1 - 3.1e-19 69.0 2.1 6.5e-05 23.6 0.0 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72190.1 - 3.8e-08 33.5 0.0 0.15 12.4 0.0 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KNZ72190.1 - 0.014 14.5 0.0 0.036 13.1 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region eIF2A PF08662.11 KNZ72190.1 - 0.22 11.4 0.0 34 4.2 0.0 2.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TRAP_alpha PF03896.16 KNZ72192.1 - 2.8e-08 33.3 0.0 3.5e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1616 PF07760.11 KNZ72192.1 - 0.032 13.6 0.1 0.083 12.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1616) tRNA_synt_1c_R1 PF04558.15 KNZ72193.1 - 0.014 15.4 0.2 0.029 14.4 0.0 1.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF5343 PF17278.2 KNZ72193.1 - 0.017 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5343) AA_permease PF00324.21 KNZ72196.1 - 4.5e-115 385.0 47.1 5.5e-115 384.7 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ72196.1 - 2.9e-33 115.3 51.8 3.6e-33 115.0 51.8 1.1 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 KNZ72196.1 - 0.014 16.1 0.4 0.014 16.1 0.4 3.7 4 1 0 4 4 4 0 PrgI family protein RT_RNaseH_2 PF17919.1 KNZ72199.1 - 1.4e-10 41.1 0.0 3.9e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ72199.1 - 2.1e-08 34.4 0.0 5.4e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Glyoxalase_4 PF13669.6 KNZ72199.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily RNA_lig_T4_1 PF09511.10 KNZ72201.1 - 3.4e-84 282.1 0.0 6.3e-84 281.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KNZ72201.1 - 3.9e-23 82.4 0.1 1.4e-22 80.6 0.0 2.0 2 0 0 2 2 2 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 KNZ72201.1 - 4.5e-17 62.3 0.0 2.2e-16 60.1 0.0 1.9 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.10 KNZ72201.1 - 0.0046 16.5 0.0 0.24 10.8 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CENP-F_leu_zip PF10473.9 KNZ72202.1 - 0.011 15.8 6.9 0.017 15.2 6.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MnmE_helical PF12631.7 KNZ72202.1 - 0.08 13.1 1.1 0.12 12.5 1.1 1.3 1 0 0 1 1 1 0 MnmE helical domain ATPase PF06745.13 KNZ72202.1 - 0.44 9.9 1.6 0.64 9.3 1.6 1.2 1 0 0 1 1 1 0 KaiC Peptidase_C12 PF01088.21 KNZ72203.1 - 1e-53 182.2 0.0 1.4e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KNZ72203.1 - 1.2e-14 54.0 0.0 2.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Med31 PF05669.12 KNZ72204.1 - 2.1e-34 117.4 8.3 2.5e-34 117.2 8.3 1.0 1 0 0 1 1 1 1 SOH1 TPT PF03151.16 KNZ72205.1 - 1.1e-23 84.0 19.6 1.4e-23 83.7 19.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KNZ72205.1 - 3.4e-06 27.3 38.4 0.00049 20.3 17.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KNZ72205.1 - 0.0013 18.0 16.4 0.01 15.1 16.4 2.2 1 1 0 1 1 1 1 UAA transporter family Zn_clus PF00172.18 KNZ72206.1 - 8.5e-06 25.8 12.3 1.4e-05 25.1 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNZ72206.1 - 0.00023 20.3 0.1 0.0004 19.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PXB PF12828.7 KNZ72206.1 - 0.042 13.8 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 PX-associated DUF218 PF02698.17 KNZ72207.1 - 1.7e-06 28.1 0.0 2.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Fungal_trans PF04082.18 KNZ72208.1 - 1.1e-24 87.0 0.9 1.7e-24 86.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KNZ72208.1 - 7.8e-07 29.3 7.8 1.1e-05 25.6 2.9 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 KNZ72208.1 - 4.8e-06 26.7 14.7 0.0031 17.9 5.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ72208.1 - 0.0081 16.9 3.5 0.0081 16.9 3.5 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KNZ72208.1 - 0.29 11.2 7.1 0.28 11.2 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNZ72208.1 - 1.9 8.9 9.0 4.5 7.7 1.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ72208.1 - 2.3 8.7 4.7 30 5.2 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Hydrolase_like PF13242.6 KNZ72209.1 - 8.5e-25 86.6 0.0 1.8e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KNZ72209.1 - 6.7e-13 48.6 0.0 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KNZ72209.1 - 0.18 11.9 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase O-FucT PF10250.9 KNZ72210.1 - 3.9e-07 30.1 0.0 2.2e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase SAM_2 PF07647.17 KNZ72211.1 - 0.00011 22.3 0.0 0.00026 21.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KNZ72211.1 - 0.0015 18.9 0.0 0.0046 17.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MyTH4 PF00784.17 KNZ72212.1 - 4.1e-30 104.4 0.0 1e-29 103.2 0.0 1.7 1 0 0 1 1 1 1 MyTH4 domain RhoGAP PF00620.27 KNZ72212.1 - 1.1e-29 103.2 0.0 1.9e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain WW PF00397.26 KNZ72212.1 - 6e-09 35.8 1.5 0.00095 19.2 2.6 2.6 2 0 0 2 2 2 2 WW domain p450 PF00067.22 KNZ72214.1 - 6.1e-66 223.0 0.0 2.6e-65 221.0 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 TetR_C_31 PF17940.1 KNZ72214.1 - 1.8 8.8 4.9 0.64 10.2 1.8 1.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FB_lectin PF07367.11 KNZ72215.1 - 0.00019 21.3 0.0 0.00021 21.2 0.0 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin FB_lectin PF07367.11 KNZ72216.1 - 5.4e-27 94.4 0.0 6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin DUF3553 PF12073.8 KNZ72216.1 - 0.08 12.7 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3553) Toxin_3 PF00537.18 KNZ72216.1 - 0.086 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Scorpion toxin-like domain MucBP PF06458.12 KNZ72216.1 - 0.09 13.8 0.5 0.5 11.4 0.5 2.0 1 1 1 2 2 2 0 MucBP domain TPT PF03151.16 KNZ72217.1 - 1.3e-37 129.8 10.9 1.9e-26 93.1 5.0 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 KNZ72217.1 - 2.7e-10 40.0 10.2 3.1e-05 23.3 3.7 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 KNZ72217.1 - 1.4e-05 25.3 29.6 0.0018 18.4 10.2 3.3 3 1 1 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KNZ72217.1 - 0.0059 15.8 2.8 1.1 8.4 0.4 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter HNH_2 PF13391.6 KNZ72218.1 - 1.2e-07 31.7 0.0 3.6e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-RVT PF13966.6 KNZ72219.1 - 0.00017 22.2 3.8 0.00027 21.6 3.8 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C3H2C3 PF17122.5 KNZ72221.1 - 0.0096 15.9 1.3 0.0096 15.9 1.3 2.4 2 0 0 2 2 2 1 Zinc-finger UCH PF00443.29 KNZ72222.1 - 2.5e-27 96.0 0.0 4.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 KNZ72222.1 - 2.9e-22 78.2 1.0 8.9e-22 76.6 0.8 2.0 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 KNZ72222.1 - 2.1e-20 72.2 1.0 1.4e-09 37.7 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KNZ72222.1 - 9.8e-16 58.2 0.0 6.5e-15 55.5 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KNZ72222.1 - 8.1e-13 48.5 6.7 1.3e-07 31.8 0.0 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein DUF4473 PF14747.6 KNZ72223.1 - 0.002 18.6 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) AbiEii PF08843.11 KNZ72223.1 - 0.0087 16.0 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system GST_N_3 PF13417.6 KNZ72224.1 - 4.1e-11 43.1 0.0 7.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ72224.1 - 5.4e-11 42.6 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KNZ72224.1 - 3.6e-08 33.6 0.0 9.3e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ72224.1 - 2.1e-06 27.6 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KNZ72224.1 - 1.3e-05 25.3 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 KNZ72224.1 - 0.0077 16.8 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ72224.1 - 0.0081 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ72224.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PQ-loop PF04193.14 KNZ72225.1 - 1.6e-26 91.9 13.0 7.9e-18 64.0 0.7 2.8 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 KNZ72225.1 - 0.00055 20.8 1.9 0.073 13.9 0.4 2.6 2 1 0 2 2 2 2 ER lumen protein retaining receptor Peptidase_U4 PF03419.13 KNZ72225.1 - 1.5 8.1 9.0 0.65 9.2 6.7 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA DUF4149 PF13664.6 KNZ72225.1 - 1.7 9.0 7.3 4.9 7.5 4.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) LAB_N PF07578.11 KNZ72225.1 - 2.4 8.3 6.8 0.56 10.3 0.9 2.5 1 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain AbiEii PF08843.11 KNZ72226.1 - 0.00028 20.9 0.2 0.00063 19.8 0.2 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system Cystatin PF00031.21 KNZ72226.1 - 0.17 12.2 0.0 26 5.2 0.0 2.3 2 0 0 2 2 2 0 Cystatin domain Mito_carr PF00153.27 KNZ72227.1 - 5.9e-62 205.6 4.3 1.2e-21 76.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2345 PF10106.9 KNZ72227.1 - 0.064 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) HMD PF03201.16 KNZ72227.1 - 0.092 13.0 0.0 0.71 10.1 0.0 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase AAA_28 PF13521.6 KNZ72228.1 - 1.9e-20 73.8 0.0 2.1e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 KNZ72228.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Sec63 PF02889.16 KNZ72229.1 - 9.1e-157 519.9 0.0 4e-85 285.1 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KNZ72229.1 - 2.2e-41 141.5 0.5 5.4e-20 71.9 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 KNZ72229.1 - 1e-33 115.8 0.0 3.4e-33 114.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 KNZ72229.1 - 2.1e-19 70.2 0.0 3.3e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNZ72229.1 - 3.2e-12 46.8 0.0 4.3e-08 33.5 0.0 4.1 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 KNZ72229.1 - 0.00073 19.8 0.0 0.16 12.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KNZ72229.1 - 0.0033 16.9 0.1 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 KNZ72229.1 - 0.043 12.9 0.0 0.12 11.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Peptidase_C39 PF03412.15 KNZ72229.1 - 0.065 13.0 0.0 0.6 9.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase C39 family AAA_30 PF13604.6 KNZ72229.1 - 0.1 12.3 0.0 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 KNZ72230.1 - 3.5e-21 75.8 0.0 1.7e-17 63.7 0.0 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72230.1 - 7.3e-06 25.5 0.7 0.068 12.4 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase RNase_H PF00075.24 KNZ72233.1 - 1.5e-10 41.5 0.0 3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 KNZ72233.1 - 1.6e-05 24.7 0.2 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ72233.1 - 0.013 15.4 0.5 0.055 13.5 0.5 2.1 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RVT PF13966.6 KNZ72233.1 - 0.014 16.1 0.2 0.056 14.2 0.2 2.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Rogdi_lz PF10259.9 KNZ72235.1 - 0.006 16.1 0.3 0.0081 15.6 0.3 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Calpain_inhib PF00748.19 KNZ72235.1 - 5.5 7.5 6.3 5.8 7.4 0.2 2.5 1 1 1 2 2 2 0 Calpain inhibitor Helicase_PWI PF18149.1 KNZ72236.1 - 3.6e-20 72.2 0.3 1.4e-19 70.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal helicase PWI domain RVP_2 PF08284.11 KNZ72237.1 - 0.079 12.7 0.2 0.36 10.6 0.0 1.8 1 1 1 2 2 2 0 Retroviral aspartyl protease TaqI_C PF12950.7 KNZ72237.1 - 0.081 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Retrotran_gag_2 PF14223.6 KNZ72238.1 - 2.3e-09 37.0 0.0 2.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KNZ72239.1 - 0.036 14.1 0.7 0.036 14.1 0.7 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ72239.1 - 0.047 13.4 0.6 0.082 12.7 0.6 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger SlyX PF04102.12 KNZ72239.1 - 0.16 12.6 0.2 0.58 10.8 0.1 2.0 2 0 0 2 2 2 0 SlyX polyprenyl_synt PF00348.17 KNZ72240.1 - 9.4e-49 165.8 0.0 1.2e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ThylakoidFormat PF11264.8 KNZ72241.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein Collagen PF01391.18 KNZ72242.1 - 0.015 15.1 6.9 0.015 15.1 6.9 1.5 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Dynamin_N PF00350.23 KNZ72243.1 - 1.7e-28 99.8 0.0 3.1e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KNZ72243.1 - 7.8e-24 84.4 0.0 1.4e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.18 KNZ72243.1 - 2.3e-10 40.5 0.0 5.4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KNZ72243.1 - 0.0001 22.3 0.0 0.00045 20.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 KNZ72243.1 - 0.031 14.0 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KNZ72243.1 - 0.071 13.5 0.1 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 KNZ72243.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Dynamin_M PF01031.20 KNZ72244.1 - 2.6e-33 115.5 0.0 1.9e-20 73.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 KNZ72244.1 - 2.4e-26 92.8 0.0 4.4e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KNZ72244.1 - 1.5e-09 37.9 0.0 5.3e-09 36.1 0.0 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KNZ72244.1 - 0.00011 22.3 0.0 0.00032 20.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KNZ72244.1 - 0.017 15.4 0.1 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KNZ72244.1 - 0.025 14.3 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KNZ72244.1 - 0.1 13.1 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KNZ72244.1 - 0.15 12.4 0.1 1.5 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Glyco_hydro_79C PF16862.5 KNZ72245.1 - 3.1e-08 34.4 0.2 3.1e-08 34.4 0.2 2.5 3 0 0 3 3 3 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF4680 PF15730.5 KNZ72245.1 - 0.14 12.5 3.9 0.26 11.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Metallophos PF00149.28 KNZ72246.1 - 2e-08 35.0 0.3 8.1e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF1798 PF08807.10 KNZ72247.1 - 0.2 11.8 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Peptidase_C14 PF00656.22 KNZ72248.1 - 2.2e-24 86.8 0.0 2.6e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain B12-binding_2 PF02607.17 KNZ72250.1 - 0.15 12.5 0.1 0.25 11.8 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain DUF2673 PF10880.8 KNZ72251.1 - 0.049 13.7 0.4 0.049 13.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Ceramidase_alk PF04734.13 KNZ72253.1 - 7.2e-217 721.0 0.0 8.4e-217 720.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KNZ72253.1 - 8.1e-42 142.9 0.0 1.6e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Cellulase PF00150.18 KNZ72255.1 - 1.4e-07 31.2 0.0 2.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-CCHC PF00098.23 KNZ72258.1 - 0.046 13.8 0.8 0.11 12.7 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3895 PF13034.6 KNZ72258.1 - 0.066 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) DUF4718 PF15842.5 KNZ72258.1 - 0.088 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) SWI-SNF_Ssr4 PF08549.10 KNZ72258.1 - 0.096 11.3 2.7 0.16 10.6 2.7 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3123 PF11321.8 KNZ72258.1 - 3.7 8.3 9.1 4.5 8.0 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) gag-asp_proteas PF13975.6 KNZ72259.1 - 2.5e-05 24.7 0.0 4.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ72259.1 - 5.7e-05 23.7 0.0 0.00011 22.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ72259.1 - 0.0013 18.5 0.1 0.0021 17.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease UPF0147 PF03685.13 KNZ72260.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Pinin_SDK_memA PF04696.13 KNZ72261.1 - 3.6e-11 43.2 12.2 3.6e-11 43.2 12.2 1.6 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF2894 PF11445.8 KNZ72261.1 - 0.88 10.0 7.4 0.076 13.5 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Trypan_PARP PF05887.11 KNZ72261.1 - 2.4 8.2 19.6 5.7 6.9 19.6 1.7 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SRP_TPR_like PF17004.5 KNZ72262.1 - 1.1e-14 54.5 0.1 1.5e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_16 PF13432.6 KNZ72262.1 - 1e-06 29.3 7.5 0.00095 19.8 2.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ72262.1 - 7.2e-06 26.4 10.3 0.0021 18.6 1.8 3.2 1 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ72262.1 - 6e-05 22.8 5.2 0.69 10.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ72262.1 - 0.00042 20.5 5.2 0.23 11.7 5.3 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KNZ72262.1 - 0.00045 20.8 9.5 0.88 10.6 0.0 4.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72262.1 - 0.0018 18.3 0.4 2.9 8.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72262.1 - 0.0063 16.6 5.5 0.024 14.8 0.2 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat SRP72 PF08492.12 KNZ72262.1 - 0.012 16.0 2.7 0.012 16.0 2.7 2.0 2 0 0 2 2 1 0 SRP72 RNA-binding domain TPR_MalT PF17874.1 KNZ72262.1 - 0.013 14.9 3.6 0.087 12.2 2.1 2.5 1 1 2 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 KNZ72262.1 - 0.02 15.5 4.9 2.2 9.1 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ72262.1 - 0.021 14.1 3.7 0.22 10.7 3.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72262.1 - 0.021 14.8 0.5 2 8.6 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72262.1 - 0.18 12.1 11.0 0.049 13.9 4.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ72262.1 - 0.39 10.6 3.9 15 5.6 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2242 PF10001.9 KNZ72264.1 - 0.0078 16.4 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2242) DUF1129 PF06570.11 KNZ72264.1 - 0.055 12.9 0.1 7.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4227 PF14004.6 KNZ72264.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4227) FAD_binding_7 PF03441.14 KNZ72266.1 - 2e-46 158.0 0.6 2.4e-46 157.8 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase 2OG-FeII_Oxy_3 PF13640.6 KNZ72269.1 - 0.075 13.9 0.0 0.22 12.4 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ACOX PF01756.19 KNZ72270.1 - 0.022 14.3 0.7 0.17 11.4 0.1 2.5 1 1 2 3 3 3 0 Acyl-CoA oxidase YrhK PF14145.6 KNZ72270.1 - 0.15 12.0 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 YrhK-like protein PGA_cap PF09587.10 KNZ72270.1 - 0.36 10.2 1.6 0.53 9.7 1.6 1.6 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap RXLR PF16810.5 KNZ72270.1 - 0.6 10.5 5.0 11 6.4 0.0 2.4 2 1 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity 4HB_MCP_1 PF12729.7 KNZ72270.1 - 1.4 8.4 10.0 1 8.9 6.3 2.2 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2207 PF09972.9 KNZ72270.1 - 2.7 6.7 4.4 0.62 8.8 0.9 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Polysacc_lyase PF14099.6 KNZ72271.1 - 5.3e-07 29.7 0.1 5.7e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide lyase BetaGal_dom4_5 PF13364.6 KNZ72271.1 - 0.0079 16.8 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_7 PF00840.20 KNZ72273.1 - 7.2e-190 631.3 15.6 6.7e-189 628.1 15.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 zf-CCHC PF00098.23 KNZ72275.1 - 0.082 13.0 1.4 0.17 12.0 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ72275.1 - 0.64 9.8 4.6 1.3 8.9 4.6 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger RT_RNaseH PF17917.1 KNZ72276.1 - 2.2e-06 27.9 0.0 4.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72276.1 - 1.2e-05 25.3 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF2967 PF11179.8 KNZ72277.1 - 0.081 11.0 0.1 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF3716 PF12511.8 KNZ72277.1 - 0.78 9.8 6.0 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) PsiB PF06290.11 KNZ72278.1 - 0.04 13.4 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) MCM PF00493.23 KNZ72279.1 - 4.7e-31 107.6 0.0 5.7e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 KNZ72279.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pyridoxal_deC PF00282.19 KNZ72280.1 - 9.8e-104 347.0 0.0 1.2e-103 346.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KNZ72280.1 - 0.024 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 KNZ72280.1 - 0.054 12.2 0.0 0.084 11.6 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 KNZ72280.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Tyrosinase PF00264.20 KNZ72281.1 - 3.7e-12 47.0 0.4 5.2e-12 46.5 0.4 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase V-SNARE PF05008.15 KNZ72283.1 - 4.2e-18 65.5 4.8 1e-17 64.3 1.1 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KNZ72283.1 - 3e-12 46.6 4.0 6.6e-12 45.5 4.0 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KNZ72283.1 - 4.8e-05 23.2 0.4 0.00022 21.1 0.0 2.0 2 0 0 2 2 2 1 Sec20 TrwC PF08751.11 KNZ72283.1 - 0.0074 15.8 0.6 0.011 15.3 0.6 1.2 1 0 0 1 1 1 1 TrwC relaxase DASH_Duo1 PF08651.10 KNZ72283.1 - 0.041 13.7 0.4 0.15 11.8 0.1 2.0 2 1 0 2 2 2 0 DASH complex subunit Duo1 Orf78 PF06024.12 KNZ72283.1 - 0.045 14.0 0.1 0.089 13.1 0.1 1.5 1 0 0 1 1 1 0 Orf78 (ac78) RPW8 PF05659.11 KNZ72283.1 - 0.074 12.7 0.7 0.18 11.5 0.2 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Lebercilin PF15619.6 KNZ72283.1 - 0.18 11.5 5.0 2.5 7.7 0.1 2.3 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KNZ72283.1 - 0.69 10.4 4.2 0.34 11.4 0.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Far-17a_AIG1 PF04750.14 KNZ72284.1 - 0.1 11.9 1.7 0.12 11.6 1.7 1.1 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein DUF4381 PF14316.6 KNZ72284.1 - 5.4 7.2 6.5 16 5.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Mpv17_PMP22 PF04117.12 KNZ72285.1 - 4.9e-23 81.1 1.0 7.8e-23 80.5 1.0 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family ApoC-I PF04691.12 KNZ72285.1 - 0.14 12.1 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) MFS_1 PF07690.16 KNZ72287.1 - 1.8e-34 119.2 49.4 2e-30 105.9 50.7 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNZ72287.1 - 1.5e-10 40.1 25.4 7.3e-10 37.9 25.5 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KNZ72290.1 - 1.2e-68 232.0 0.0 3.7e-68 230.4 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 CE2_N PF17996.1 KNZ72292.1 - 1.1e-05 25.4 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Big_3_5 PF16640.5 KNZ72292.1 - 3.1 8.1 6.2 0.52 10.5 0.2 2.7 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) CBM_1 PF00734.18 KNZ72293.1 - 1.7e-11 43.8 12.5 1.7e-11 43.8 12.5 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Esterase_phd PF10503.9 KNZ72293.1 - 4.7e-08 32.8 0.1 5.8e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase RNase_H PF00075.24 KNZ72294.1 - 0.0047 17.1 0.1 0.0087 16.2 0.0 1.5 1 1 0 1 1 1 1 RNase H SpoU_methylase PF00588.19 KNZ72294.1 - 0.077 13.2 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 SpoU rRNA Methylase family RVT_1 PF00078.27 KNZ72295.1 - 1.4e-05 24.7 0.1 1.7e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 KNZ72296.1 - 0.00039 20.0 0.0 0.00039 20.0 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KNZ72297.1 - 6.2e-11 42.2 0.8 8.5e-11 41.7 0.8 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF4106 PF13388.6 KNZ72298.1 - 3.3 6.8 10.2 4.2 6.5 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) KDZ PF18758.1 KNZ72299.1 - 9.9e-49 165.9 1.4 1.5e-48 165.4 1.4 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 KNZ72299.1 - 3e-09 37.0 0.0 1.4e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases BAR_2 PF10455.9 KNZ72301.1 - 1.7e-17 63.5 1.2 1.9e-17 63.3 1.2 1.0 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KNZ72301.1 - 1e-05 25.3 1.8 1.2e-05 25.1 1.8 1.0 1 0 0 1 1 1 1 BAR domain PAP_fibrillin PF04755.12 KNZ72301.1 - 0.035 14.0 0.3 0.059 13.3 0.2 1.4 1 1 0 1 1 1 0 PAP_fibrillin CENP-B_dimeris PF09026.10 KNZ72302.1 - 0.02 15.3 4.7 0.02 15.3 4.7 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 KNZ72302.1 - 2.4 6.1 6.3 3 5.8 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 KNZ72302.1 - 8.6 5.0 5.6 11 4.7 5.6 1.1 1 0 0 1 1 1 0 Presenilin Pyr_redox_2 PF07992.14 KNZ72303.1 - 7.7e-65 219.0 1.7 1.1e-64 218.5 1.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KNZ72303.1 - 4.4e-33 113.8 1.0 1.3e-32 112.3 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KNZ72303.1 - 8.1e-20 71.2 2.2 4.9e-18 65.5 0.2 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ72303.1 - 3.5e-12 46.2 1.2 8.2e-12 45.0 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ72303.1 - 1.6e-07 30.8 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KNZ72303.1 - 1e-06 27.8 0.7 0.00053 18.8 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KNZ72303.1 - 1.1e-05 24.9 0.2 2.2e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ72303.1 - 0.00014 21.0 2.3 0.023 13.8 0.6 2.5 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KNZ72303.1 - 0.0023 18.1 0.3 0.0062 16.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 KNZ72303.1 - 0.018 14.3 0.4 3.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KNZ72303.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KNZ72303.1 - 0.2 11.6 0.9 0.87 9.6 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 KNZ72303.1 - 1.7 7.6 6.3 0.41 9.7 0.1 2.8 3 1 1 4 4 4 0 Glucose inhibited division protein A DAO PF01266.24 KNZ72303.1 - 2 7.9 9.8 2.4 7.7 0.0 2.9 3 1 0 3 3 3 0 FAD dependent oxidoreductase WD40 PF00400.32 KNZ72305.1 - 2.5e-47 157.9 25.5 1.1e-07 32.4 0.1 7.9 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72305.1 - 6.8e-16 58.4 4.2 0.00011 22.4 0.1 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ72305.1 - 3.9e-11 42.3 6.1 0.012 14.2 0.2 4.9 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ72305.1 - 4.7e-05 22.5 1.9 0.11 11.4 0.0 4.0 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ72305.1 - 0.00089 19.2 0.5 0.022 14.6 0.1 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Pox_A_type_inc PF04508.12 KNZ72305.1 - 0.05 13.5 0.3 0.18 11.7 0.3 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AidB_N PF18158.1 KNZ72305.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain SPOUT_MTase_2 PF14419.6 KNZ72306.1 - 0.11 11.9 0.1 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP VCBS PF13517.6 KNZ72308.1 - 3.2e-24 85.3 14.5 1.3e-07 32.1 1.7 5.6 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 KNZ72308.1 - 0.015 15.4 28.3 0.56 10.4 1.1 6.5 7 1 1 8 8 8 0 FG-GAP repeat TcdB_toxin_midN PF12256.8 KNZ72308.1 - 0.7 9.2 6.9 12 5.2 0.0 4.7 4 2 1 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region Cerato-platanin PF07249.12 KNZ72310.1 - 1.4e-45 154.3 0.8 1.6e-45 154.1 0.8 1.0 1 0 0 1 1 1 1 Cerato-platanin Plant_tran PF04827.14 KNZ72310.1 - 0.0011 18.7 0.1 0.0013 18.3 0.1 1.1 1 0 0 1 1 1 1 Plant transposon protein Cerato-platanin PF07249.12 KNZ72311.1 - 1e-46 157.9 0.3 1.2e-46 157.7 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin ABC2_membrane PF01061.24 KNZ72312.1 - 3.6e-39 134.4 18.6 3.6e-39 134.4 18.6 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KNZ72312.1 - 4.1e-24 85.6 0.0 8.4e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 KNZ72312.1 - 0.00027 20.1 25.8 0.00027 20.1 25.8 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 KNZ72312.1 - 0.0019 18.1 0.3 0.005 16.8 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KNZ72312.1 - 0.0068 16.7 0.1 0.018 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 KNZ72312.1 - 0.01 15.7 1.1 1.4 8.7 0.1 2.2 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KNZ72312.1 - 0.02 15.3 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KNZ72312.1 - 0.024 15.2 0.1 0.044 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KNZ72312.1 - 0.03 14.0 0.1 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 KNZ72312.1 - 0.034 14.3 0.2 0.069 13.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ72312.1 - 0.057 13.8 0.9 0.19 12.1 0.3 2.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 KNZ72312.1 - 0.061 13.6 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KNZ72312.1 - 0.083 12.7 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 KNZ72312.1 - 0.093 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 KNZ72312.1 - 0.1 12.3 0.3 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 AAA domain EphA2_TM PF14575.6 KNZ72312.1 - 0.16 12.9 1.0 0.28 12.1 0.0 1.9 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain AAA_23 PF13476.6 KNZ72312.1 - 0.17 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain HD PF01966.22 KNZ72312.1 - 0.19 12.0 0.2 6.7 7.0 0.0 2.3 2 0 0 2 2 2 0 HD domain COX17 PF05051.13 KNZ72313.1 - 4.3e-22 78.2 4.7 4.3e-22 78.2 4.7 1.6 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) E1-E2_ATPase PF00122.20 KNZ72314.1 - 8.5e-39 132.9 2.4 1.4e-36 125.7 0.5 3.2 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNZ72314.1 - 5.8e-24 84.8 12.2 2.4e-17 63.2 1.9 3.4 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KNZ72314.1 - 1.7e-22 80.7 0.0 1.2e-20 74.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ72314.1 - 8e-17 61.1 0.0 1.6e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNZ72314.1 - 4.9e-13 48.5 0.0 1.1e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNZ72314.1 - 0.0001 22.1 1.2 0.028 14.2 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_efflux PF01545.21 KNZ72314.1 - 0.00065 19.5 1.2 0.1 12.3 1.7 2.7 2 1 0 2 2 2 1 Cation efflux family DUF1691 PF07950.11 KNZ72315.1 - 1.8e-06 28.6 0.9 0.00039 21.1 0.5 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) RST PF12174.8 KNZ72315.1 - 0.17 11.9 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain Pkinase PF00069.25 KNZ72316.1 - 1.9e-23 83.2 0.0 2.5e-18 66.4 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72316.1 - 2.4e-10 40.2 0.0 1.2e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ72316.1 - 0.00052 19.4 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 KNZ72316.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_terminal PF02459.15 KNZ72316.1 - 0.27 9.6 2.9 0.48 8.8 2.9 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF5320 PF17253.2 KNZ72316.1 - 0.38 11.8 15.4 1.6 9.8 8.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Sporozoite_P67 PF05642.11 KNZ72316.1 - 0.72 7.9 3.7 0.92 7.5 3.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Keratin_2_head PF16208.5 KNZ72316.1 - 1.2 9.2 14.6 0.31 11.2 9.4 2.1 2 0 0 2 2 2 0 Keratin type II head F-box PF00646.33 KNZ72317.1 - 1.4e-09 37.6 1.6 3.8e-09 36.2 1.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ72317.1 - 7.8e-06 25.7 0.3 1.7e-05 24.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KNZ72317.1 - 0.0013 18.5 3.8 0.0021 17.9 0.4 2.2 2 0 0 2 2 2 1 F-box VapB_antitoxin PF09957.9 KNZ72317.1 - 0.16 11.9 1.0 0.64 10.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Alanine_zipper PF11839.8 KNZ72318.1 - 1e-05 25.8 70.0 0.98 9.8 10.6 5.1 1 1 4 5 5 5 5 Alanine-zipper, major outer membrane lipoprotein Terpene_synth_C PF03936.16 KNZ72319.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DDOST_48kD PF03345.14 KNZ72320.1 - 1.1e-127 426.3 0.0 1.3e-127 426.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BCSC_C PF05420.11 KNZ72320.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Endotoxin_M PF00555.19 KNZ72320.1 - 0.034 14.2 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin ADK PF00406.22 KNZ72321.1 - 6.1e-59 198.4 0.0 7.5e-59 198.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KNZ72321.1 - 2.9e-22 79.5 0.1 7.9e-22 78.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 KNZ72321.1 - 5.7e-17 61.4 0.0 1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KNZ72321.1 - 0.00036 21.1 0.0 0.00088 19.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNZ72321.1 - 0.0024 18.0 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fungal_trans PF04082.18 KNZ72322.1 - 3.3e-10 39.5 0.2 5.2e-10 38.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ72322.1 - 0.0069 16.5 5.8 0.014 15.5 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain gag-asp_proteas PF13975.6 KNZ72323.1 - 6.8e-05 23.4 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ72323.1 - 0.00077 20.1 0.0 0.0017 18.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease BLACT_WH PF17778.1 KNZ72324.1 - 1.2e-15 57.2 0.1 3.7e-15 55.6 0.2 1.8 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KNZ72324.1 - 2.9e-12 47.0 2.4 2e-10 41.0 2.3 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RT_RNaseH PF17917.1 KNZ72324.1 - 0.00025 21.3 0.0 0.00052 20.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72324.1 - 0.0015 18.5 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Lactamase_B_2 PF12706.7 KNZ72324.1 - 0.11 12.0 0.2 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Beta-lactamase superfamily domain MA3 PF02847.17 KNZ72326.1 - 4.6e-26 91.0 0.1 9.1e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 MA3 domain CDC45 PF02724.14 KNZ72326.1 - 0.25 9.6 14.3 0.036 12.4 0.8 2.3 2 0 0 2 2 2 0 CDC45-like protein DUF4598 PF15370.6 KNZ72326.1 - 0.73 10.3 12.4 0.48 10.9 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) FAM176 PF14851.6 KNZ72326.1 - 0.86 9.3 9.0 3.9 7.1 0.4 2.4 2 0 0 2 2 2 0 FAM176 family AF-4 PF05110.13 KNZ72326.1 - 1.9 6.5 24.0 0.36 8.9 18.9 1.8 2 0 0 2 2 2 0 AF-4 proto-oncoprotein PBP1_TM PF14812.6 KNZ72326.1 - 3.7 8.0 11.8 1.9 8.9 2.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA2 PF07543.12 KNZ72326.1 - 7 6.6 11.0 2.1 8.3 2.2 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 HEAT PF02985.22 KNZ72327.1 - 0.0074 16.5 0.1 0.026 14.7 0.1 1.9 2 0 0 2 2 2 1 HEAT repeat Asp_protease_2 PF13650.6 KNZ72328.1 - 0.1 13.2 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Pkinase_fungal PF17667.1 KNZ72330.1 - 1.4e-21 76.8 0.0 1.3e-13 50.6 0.0 2.3 1 1 0 2 2 2 2 Fungal protein kinase Glucodextran_N PF09137.11 KNZ72333.1 - 0.042 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Glucodextranase, domain N DNA_pol_alpha_N PF12254.8 KNZ72334.1 - 0.076 13.1 1.6 0.15 12.2 1.6 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Helitron_like_N PF14214.6 KNZ72336.1 - 6.4e-10 39.6 0.0 6.8e-07 29.7 0.0 2.3 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ72337.1 - 8e-05 22.0 0.0 9.1e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ72337.1 - 0.018 14.7 0.1 0.023 14.4 0.1 1.1 1 0 0 1 1 1 0 AAA domain Pkinase_fungal PF17667.1 KNZ72338.1 - 1.9e-26 92.8 0.0 1.9e-25 89.5 0.0 1.9 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KNZ72339.1 - 1.3e-09 37.8 0.0 1.9e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72339.1 - 0.0024 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNase_H PF00075.24 KNZ72341.1 - 2.8e-08 34.1 0.0 7e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ72341.1 - 0.0023 18.6 3.2 0.0068 17.1 3.2 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase TFIIA PF03153.13 KNZ72343.1 - 0.0049 16.9 6.5 0.006 16.6 6.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ribonucleas_3_3 PF14622.6 KNZ72344.1 - 4.2e-07 30.2 0.0 1.1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 KNZ72344.1 - 2.1e-06 28.3 0.0 6.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KNZ72344.1 - 0.014 16.0 0.0 0.039 14.6 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease III domain Helicase_C PF00271.31 KNZ72344.1 - 0.18 12.1 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SNF2_N PF00176.23 KNZ72345.1 - 1.4e-35 122.7 0.0 2.3e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-PHD-like PF15446.6 KNZ72345.1 - 4.3e-06 26.4 4.9 4.3e-06 26.4 4.9 3.2 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 KNZ72345.1 - 7.1e-06 26.1 0.0 2.1e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.24 KNZ72345.1 - 0.014 15.3 4.8 1.2 9.2 0.2 3.2 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain C1_1 PF00130.22 KNZ72345.1 - 0.083 12.8 0.3 0.083 12.8 0.3 4.0 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_22 PF13401.6 KNZ72345.1 - 0.092 13.0 0.1 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain PHD PF00628.29 KNZ72345.1 - 1.6 8.7 18.0 0.87 9.5 0.1 4.4 4 1 0 4 4 4 0 PHD-finger LIDHydrolase PF10230.9 KNZ72346.1 - 4.3e-16 59.3 0.1 4.8e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Sec8_exocyst PF04048.14 KNZ72347.1 - 1e-25 90.3 0.2 2.1e-25 89.3 0.2 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KNZ72347.1 - 5.8e-05 22.5 0.2 0.00013 21.3 0.2 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Helitron_like_N PF14214.6 KNZ72349.1 - 2.1e-24 86.8 0.0 2.6e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RT_RNaseH_2 PF17919.1 KNZ72350.1 - 0.0026 17.8 0.0 0.0071 16.4 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ72350.1 - 0.02 15.2 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase DUF4894 PF16235.5 KNZ72350.1 - 0.052 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) DUF1623 PF07785.11 KNZ72350.1 - 0.2 11.8 1.6 0.54 10.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1623) Pkinase PF00069.25 KNZ72354.1 - 3.1e-09 36.6 0.0 4.5e-08 32.8 0.0 2.2 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72354.1 - 0.021 14.1 0.0 0.045 13.0 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase MRP-S22 PF10245.9 KNZ72355.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S22 Ank_2 PF12796.7 KNZ72356.1 - 5.9e-19 68.5 0.3 1.7e-14 54.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ72356.1 - 3.1e-16 59.2 1.5 6.1e-06 26.4 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ72356.1 - 4.6e-16 59.0 4.9 2.9e-09 37.3 0.1 4.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ72356.1 - 1.1e-14 53.1 0.7 0.0007 19.9 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KNZ72356.1 - 1.6e-10 41.0 9.3 0.0057 17.1 0.6 5.8 5 1 0 5 5 5 3 Ankyrin repeat AAA_23 PF13476.6 KNZ72357.1 - 6.8 7.1 6.9 12 6.3 6.9 1.3 1 0 0 1 1 1 0 AAA domain FCH PF00611.23 KNZ72358.1 - 2e-13 50.4 0.1 5.8e-13 48.9 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain FAD-SLDH PF12318.8 KNZ72359.1 - 0.12 12.4 0.3 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Cwf_Cwc_15 PF04889.12 KNZ72361.1 - 3.9e-86 288.8 25.9 4.4e-86 288.6 25.9 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2167 PF09935.9 KNZ72361.1 - 0.018 14.2 0.7 0.018 14.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Nop14 PF04147.12 KNZ72361.1 - 0.028 12.7 21.9 0.033 12.4 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 KNZ72361.1 - 0.11 11.1 23.7 0.17 10.5 23.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Roughex PF06020.11 KNZ72361.1 - 0.52 9.4 14.1 0.65 9.0 14.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 KNZ72361.1 - 1.9 6.7 20.0 2.4 6.3 20.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KNZ72361.1 - 2 7.1 10.8 2.2 7.0 10.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KNZ72361.1 - 3.8 6.4 6.9 5 6.0 6.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ALMT PF11744.8 KNZ72361.1 - 9.8 4.9 7.7 14 4.4 7.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PseudoU_synth_2 PF00849.22 KNZ72362.1 - 3.8e-26 92.1 0.0 5.6e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box PF00646.33 KNZ72363.1 - 3.1 7.8 8.9 9.1 6.3 1.0 3.2 3 0 0 3 3 3 0 F-box domain ThiF PF00899.21 KNZ72364.1 - 3e-31 108.6 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KNZ72364.1 - 4.8e-10 39.9 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Aminotran_5 PF00266.19 KNZ72366.1 - 2.2e-27 96.0 0.0 8.1e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Sas10_Utp3 PF04000.15 KNZ72366.1 - 0.7 10.6 2.2 5.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Sas10/Utp3/C1D family p450 PF00067.22 KNZ72367.1 - 1.1e-72 245.3 0.0 3.3e-72 243.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Uso1_p115_head PF04869.14 KNZ72368.1 - 1.6e-46 158.9 0.0 5.7e-45 153.8 0.0 3.1 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KNZ72368.1 - 3.7e-14 53.2 24.6 7.1e-14 52.3 24.6 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KNZ72368.1 - 0.0001 21.3 9.6 0.00016 20.7 9.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HEAT_2 PF13646.6 KNZ72368.1 - 0.022 15.1 2.8 0.67 10.4 0.0 3.9 2 1 1 3 3 3 0 HEAT repeats DUF3818 PF12825.7 KNZ72368.1 - 0.026 13.5 6.9 0.043 12.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) FAM76 PF16046.5 KNZ72368.1 - 0.12 11.7 6.2 0.18 11.2 6.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4140 PF13600.6 KNZ72368.1 - 0.15 12.5 3.7 0.58 10.6 3.7 2.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) MIF4G_like_2 PF09090.11 KNZ72368.1 - 0.22 10.9 6.2 0.51 9.8 6.2 1.6 1 0 0 1 1 1 0 MIF4G like Seryl_tRNA_N PF02403.22 KNZ72368.1 - 0.23 11.7 13.0 0.14 12.4 10.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FH2 PF02181.23 KNZ72368.1 - 0.35 9.9 10.7 0.63 9.1 10.7 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Lectin_N PF03954.14 KNZ72368.1 - 0.53 10.0 5.6 1.5 8.5 5.3 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DprA_WH PF17782.1 KNZ72368.1 - 0.58 10.3 5.5 0.26 11.4 0.7 2.9 2 0 0 2 2 2 0 DprA winged helix domain Golgin_A5 PF09787.9 KNZ72368.1 - 0.61 9.5 13.9 1 8.8 13.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2570 PF10828.8 KNZ72368.1 - 1.3 8.9 5.6 4.4 7.2 5.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CKAP2_C PF15297.6 KNZ72368.1 - 1.4 7.9 10.4 2.2 7.3 10.4 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Macoilin PF09726.9 KNZ72368.1 - 1.4 7.3 10.1 2.2 6.7 10.1 1.2 1 0 0 1 1 1 0 Macoilin family ACCA PF03255.14 KNZ72368.1 - 1.9 8.3 6.5 3.4 7.5 6.5 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF1759 PF03564.15 KNZ72368.1 - 2.1 8.3 5.9 13 5.7 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) NPV_P10 PF05531.12 KNZ72368.1 - 3.5 8.1 5.9 19 5.8 0.2 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 KNZ72368.1 - 4.3 7.8 18.3 0.61 10.5 7.1 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain FlxA PF14282.6 KNZ72368.1 - 4.8 7.2 16.9 7.1 6.7 16.2 1.6 1 1 0 1 1 1 0 FlxA-like protein LPP PF04728.13 KNZ72368.1 - 9.7 6.7 7.6 5.9 7.4 3.6 2.6 2 1 1 3 3 2 0 Lipoprotein leucine-zipper Arm-DNA-bind_5 PF17293.2 KNZ72369.1 - 0.059 13.8 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Arm DNA-binding domain ATG16 PF08614.11 KNZ72370.1 - 0.0038 17.5 2.9 0.0038 17.5 2.9 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 KNZ72370.1 - 0.089 12.3 5.2 0.22 11.0 1.8 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit CK2S PF15011.6 KNZ72370.1 - 0.099 12.5 5.7 4.3 7.2 1.7 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate CALCOCO1 PF07888.11 KNZ72370.1 - 0.13 11.1 9.8 0.067 12.1 6.1 2.0 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HIP1_clath_bdg PF16515.5 KNZ72370.1 - 0.31 11.7 7.6 0.69 10.6 2.7 2.6 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SHE3 PF17078.5 KNZ72370.1 - 0.4 10.4 7.5 0.11 12.2 3.9 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 FapA PF03961.13 KNZ72370.1 - 0.42 9.2 3.4 2.3 6.7 1.8 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A FUSC PF04632.12 KNZ72370.1 - 0.57 8.6 2.8 0.77 8.2 0.7 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF5082 PF16888.5 KNZ72370.1 - 0.67 10.2 8.1 14 5.9 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) zf-RVT PF13966.6 KNZ72373.1 - 0.00016 22.3 1.4 0.00024 21.7 1.4 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KNZ72374.1 - 6e-10 39.5 0.1 8.3e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KNZ72374.1 - 0.0031 17.3 0.0 0.017 14.9 0.0 2.0 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.24 KNZ72377.1 - 5.4e-06 26.6 0.0 6.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 RNase H DUF3819 PF12842.7 KNZ72377.1 - 0.046 13.7 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF1772 PF08592.11 KNZ72378.1 - 0.027 14.8 0.9 0.2 12.0 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Ank_2 PF12796.7 KNZ72379.1 - 4.8e-16 59.1 0.8 6.1e-11 42.8 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ72379.1 - 2.3e-13 50.1 0.4 0.00023 21.4 0.0 3.6 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ72379.1 - 5.4e-11 41.7 0.7 0.0024 18.2 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KNZ72379.1 - 3.1e-08 34.0 0.1 0.00037 21.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KNZ72379.1 - 1.8e-05 25.0 2.3 0.074 13.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat MT PF12777.7 KNZ72379.1 - 0.11 11.5 0.3 0.15 11.0 0.3 1.2 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor IKI3 PF04762.12 KNZ72380.1 - 3.2e-252 839.6 0.4 7.8e-195 649.7 0.0 2.1 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 KNZ72380.1 - 6.9e-07 29.5 0.0 1.6 9.1 0.0 5.7 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4298 PF14131.6 KNZ72380.1 - 0.14 12.1 0.5 1.3 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Clathrin PF00637.20 KNZ72380.1 - 0.19 11.6 1.3 0.74 9.7 0.0 2.5 2 1 1 3 3 3 0 Region in Clathrin and VPS Efg1 PF10153.9 KNZ72381.1 - 8.8e-36 122.7 13.1 1.7e-35 121.8 13.1 1.5 1 0 0 1 1 1 1 rRNA-processing protein Efg1 Tropomyosin_1 PF12718.7 KNZ72381.1 - 0.085 13.0 9.2 0.15 12.3 9.2 1.5 1 0 0 1 1 1 0 Tropomyosin like FUSC PF04632.12 KNZ72381.1 - 0.37 9.3 0.3 0.44 9.0 0.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3496 PF12001.8 KNZ72381.1 - 0.43 11.0 7.0 0.14 12.5 4.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Fib_alpha PF08702.10 KNZ72381.1 - 0.44 10.7 3.9 0.76 10.0 3.5 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FAD_binding_4 PF01565.23 KNZ72382.1 - 2.4e-11 43.5 0.1 0.00063 19.5 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.12 KNZ72382.1 - 1.1e-06 28.7 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KNZ72382.1 - 0.0086 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_3_C PF01915.22 KNZ72384.1 - 3.4e-51 174.1 0.0 5.5e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ72384.1 - 5.9e-51 173.7 0.0 8.1e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ72384.1 - 2.8e-22 78.6 1.0 5.6e-22 77.6 1.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KNZ72384.1 - 0.17 11.0 0.0 0.33 10.0 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain PEP_mutase PF13714.6 KNZ72385.1 - 4.6e-39 134.3 4.2 1.2e-38 132.9 4.2 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KNZ72385.1 - 3e-19 68.9 0.8 4.2e-19 68.4 0.8 1.1 1 0 0 1 1 1 1 Isocitrate lyase family RVT_thumb PF06817.14 KNZ72388.1 - 0.067 13.0 1.1 0.11 12.4 0.2 1.8 1 1 1 2 2 2 0 Reverse transcriptase thumb domain AbrB_C PF18277.1 KNZ72388.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 AbrB C-terminal domain DUF5417 PF17438.2 KNZ72388.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5417) HSP70 PF00012.20 KNZ72389.1 - 3e-39 134.7 0.1 3.2e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DMRL_synthase PF00885.19 KNZ72389.1 - 0.0024 17.7 0.1 0.0027 17.5 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RNase_H PF00075.24 KNZ72390.1 - 0.0015 18.7 0.3 0.0029 17.8 0.0 1.6 2 0 0 2 2 2 1 RNase H Retrotran_gag_2 PF14223.6 KNZ72391.1 - 0.0025 17.5 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KNZ72391.1 - 0.13 12.4 3.4 0.36 11.0 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle Patatin PF01734.22 KNZ72392.1 - 3.6e-08 33.8 0.0 2.6e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KNZ72393.1 - 0.00084 18.6 0.0 0.018 14.2 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain TPR_10 PF13374.6 KNZ72394.1 - 5.7e-47 156.4 0.2 7.4e-10 38.4 0.0 6.0 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72394.1 - 2.1e-45 152.9 2.2 1.4e-13 51.0 0.0 4.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ72394.1 - 3.2e-11 43.2 6.3 1.5e-07 31.2 3.1 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KNZ72394.1 - 2.3e-09 36.6 4.3 0.37 11.0 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ72394.1 - 1.4e-07 32.1 4.9 0.01 16.4 0.2 4.0 1 1 3 4 4 4 2 Domain of unknown function (DUF4404) TPR_19 PF14559.6 KNZ72394.1 - 3.7e-06 27.3 2.2 0.15 12.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72394.1 - 5.6e-06 26.4 0.2 5.5 7.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72394.1 - 3.7e-05 23.4 3.1 13 6.1 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ72394.1 - 0.00012 22.4 0.0 12 6.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72394.1 - 0.00013 21.9 1.0 4.4 7.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ72394.1 - 0.0031 17.3 1.4 5.9 6.9 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat FANCI_S2 PF14676.6 KNZ72394.1 - 0.0041 17.5 3.0 0.26 11.6 0.2 2.4 1 1 1 2 2 2 1 FANCI solenoid 2 TPR_16 PF13432.6 KNZ72394.1 - 0.011 16.3 0.0 30 5.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat UDG PF03167.19 KNZ72394.1 - 0.021 14.8 0.0 2.6 8.0 0.0 2.9 1 1 1 3 3 3 0 Uracil DNA glycosylase superfamily AviRa PF11599.8 KNZ72394.1 - 0.03 13.8 1.0 0.11 11.9 0.1 2.1 1 1 1 2 2 2 0 RRNA methyltransferase AviRa DUF1897 PF09005.10 KNZ72394.1 - 0.65 9.5 4.5 44 3.7 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) COG2 PF06148.11 KNZ72394.1 - 1.3 9.1 4.7 2.2 8.4 0.6 2.4 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5340 PF17275.2 KNZ72394.1 - 5.4 7.2 6.1 33 4.7 0.1 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5340) APH PF01636.23 KNZ72396.1 - 2.4e-05 24.4 0.4 0.00025 21.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ72396.1 - 0.0035 17.0 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 KNZ72396.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNZ72396.1 - 0.013 14.8 0.0 0.035 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein kinase domain CDC50 PF03381.15 KNZ72397.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family P22_portal PF16510.5 KNZ72398.1 - 0.056 12.1 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage P22-like portal protein NB-ARC PF00931.22 KNZ72399.1 - 0.022 13.9 0.0 0.027 13.7 0.0 1.0 1 0 0 1 1 1 0 NB-ARC domain APH PF01636.23 KNZ72400.1 - 0.00014 21.9 1.6 0.0036 17.3 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72400.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.20 KNZ72400.1 - 0.1 12.2 0.0 0.26 10.8 0.0 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Foamy_virus_ENV PF03408.14 KNZ72401.1 - 0.12 10.2 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein TAP42 PF04177.12 KNZ72402.1 - 0.1 11.7 0.1 0.15 11.2 0.1 1.2 1 0 0 1 1 1 0 TAP42-like family PGI PF00342.19 KNZ72402.1 - 0.24 9.9 0.1 0.37 9.3 0.1 1.1 1 0 0 1 1 1 0 Phosphoglucose isomerase gag-asp_proteas PF13975.6 KNZ72404.1 - 6.2e-05 23.5 0.0 6.8e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ72404.1 - 0.00016 22.2 0.0 0.00019 22.0 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease DUF4470 PF14737.6 KNZ72407.1 - 7.1e-21 74.2 0.1 1.2e-20 73.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KNZ72407.1 - 0.00018 21.5 7.1 0.00043 20.3 7.1 1.6 1 0 0 1 1 1 1 MYND finger AMP-binding PF00501.28 KNZ72408.1 - 7.3e-36 123.7 0.0 1.7e-35 122.5 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KNZ72408.1 - 9.5e-19 67.6 0.0 1.4e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KNZ72408.1 - 3.4e-05 23.4 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KNZ72408.1 - 0.0034 17.7 0.0 0.0091 16.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF4470 PF14737.6 KNZ72409.1 - 1.9e-05 24.7 0.0 5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) Flavin_Reduct PF01613.18 KNZ72410.1 - 1.5e-20 73.8 0.0 1.7e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Apo-CIII PF05778.12 KNZ72412.1 - 0.085 12.5 0.5 0.11 12.2 0.5 1.3 1 1 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) FAM167 PF11652.8 KNZ72412.1 - 0.11 13.0 0.0 0.13 12.8 0.0 1.3 1 1 0 1 1 1 0 FAM167 FMO-like PF00743.19 KNZ72413.1 - 4.3e-14 51.8 0.3 1.1e-12 47.2 0.3 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ72413.1 - 3.4e-11 42.9 0.0 2.8e-08 33.3 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ72413.1 - 4.7e-11 42.4 0.0 5.8e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KNZ72413.1 - 2.3e-09 36.9 0.0 1.5e-06 27.7 0.0 3.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ72413.1 - 5.7e-08 32.9 0.1 9.9e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ72413.1 - 5.2e-05 23.0 0.8 0.27 10.8 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ72413.1 - 0.00039 20.4 2.8 0.13 12.3 0.0 4.2 5 1 0 5 5 5 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KNZ72413.1 - 0.0059 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KNZ72413.1 - 0.042 13.9 0.2 0.41 10.7 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KNZ72413.1 - 0.045 12.8 0.0 0.64 9.0 0.0 2.2 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KNZ72413.1 - 0.08 13.5 3.1 10 6.7 0.1 3.0 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNZ72413.1 - 0.19 10.8 2.5 1.8 7.5 0.0 2.8 3 1 0 3 3 3 0 Glucose inhibited division protein A FMO-like PF00743.19 KNZ72414.1 - 1.3e-15 56.8 0.2 2.4e-15 56.0 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ72414.1 - 2.9e-11 43.1 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ72414.1 - 7.5e-11 42.1 0.0 6.5e-09 35.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KNZ72414.1 - 1.8e-10 40.6 0.0 7.1e-09 35.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ72414.1 - 2.2e-10 40.2 0.0 2.3e-09 36.9 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KNZ72414.1 - 6.5e-05 23.0 0.1 0.069 13.1 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 KNZ72414.1 - 0.00018 21.2 0.0 0.13 11.8 0.0 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KNZ72414.1 - 0.0032 18.0 0.6 1.9 9.1 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KNZ72414.1 - 0.0057 16.0 0.1 0.017 14.5 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KNZ72414.1 - 0.011 16.1 0.0 6.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Thi4 PF01946.17 KNZ72414.1 - 0.016 14.4 0.3 0.22 10.7 0.0 2.4 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 KNZ72414.1 - 0.021 13.9 0.0 4.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KNZ72414.1 - 0.032 12.9 0.5 0.2 10.3 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 KNZ72414.1 - 0.044 12.8 0.2 0.98 8.4 0.0 2.2 1 1 1 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KNZ72414.1 - 0.07 12.4 0.3 1 8.6 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KNZ72414.1 - 0.26 11.3 0.4 4.1 7.5 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_16 PF00722.21 KNZ72418.1 - 3.2e-13 49.5 4.9 6.9e-12 45.2 3.9 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Adaptin_N PF01602.20 KNZ72419.1 - 1.9e-75 254.5 12.8 1.8e-62 211.6 8.0 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 KNZ72419.1 - 6.6e-14 52.3 6.5 1.8e-12 47.6 3.1 3.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ72419.1 - 0.00081 19.7 0.3 0.47 10.9 0.0 4.3 2 1 3 5 5 5 2 HEAT repeats Helitron_like_N PF14214.6 KNZ72420.1 - 1.6e-64 217.6 0.1 2.5e-64 217.0 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ72420.1 - 0.059 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) MitMem_reg PF13012.6 KNZ72421.1 - 0.034 14.5 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ72422.1 - 2.5e-51 174.9 0.1 2.8e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ72422.1 - 1e-05 25.4 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ72422.1 - 0.0051 16.6 0.2 0.013 15.2 0.2 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ72422.1 - 0.039 14.3 0.1 0.18 12.2 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KNZ72422.1 - 0.062 13.7 0.0 0.066 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FMO-like PF00743.19 KNZ72424.1 - 6e-15 54.7 0.0 1.3e-14 53.5 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ72424.1 - 2.2e-11 43.5 0.0 9.3e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ72424.1 - 6.3e-11 42.1 0.0 3.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ72424.1 - 2.2e-10 40.6 0.1 5.7e-09 36.1 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KNZ72424.1 - 2.8e-10 39.9 0.0 4e-07 29.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KNZ72424.1 - 1.3e-05 25.0 0.1 0.022 14.4 0.0 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ72424.1 - 9.8e-05 22.4 0.4 0.032 14.2 0.0 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ72424.1 - 0.00056 20.4 1.1 1.6 9.4 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ72424.1 - 0.00072 18.9 0.1 0.006 15.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.19 KNZ72424.1 - 0.0034 16.8 0.1 0.008 15.6 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KNZ72424.1 - 0.0062 15.7 0.0 3.6 6.6 0.0 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 KNZ72424.1 - 0.024 15.1 0.2 6.6 7.2 0.0 2.6 3 1 0 3 3 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KNZ72424.1 - 0.033 13.2 0.0 0.21 10.6 0.0 2.1 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 KNZ72424.1 - 0.034 12.9 0.7 0.12 11.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KNZ72424.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KNZ72424.1 - 0.16 12.0 0.2 2 8.5 0.0 2.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KNZ72424.1 - 0.19 11.0 0.7 2.1 7.6 0.2 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain APH PF01636.23 KNZ72425.1 - 0.00018 21.5 0.1 0.00021 21.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72425.1 - 0.006 16.0 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ72425.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ72425.1 - 0.049 12.6 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain AICARFT_IMPCHas PF01808.18 KNZ72428.1 - 1.1e-86 291.0 0.0 1.4e-86 290.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KNZ72428.1 - 1.2e-24 86.3 0.0 2.3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain HD_3 PF13023.6 KNZ72429.1 - 6.2e-27 94.5 0.6 7.7e-27 94.2 0.6 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KNZ72429.1 - 6.8e-07 29.2 0.1 8.7e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 KNZ72429.1 - 2.9e-06 27.5 0.3 4.1e-06 27.0 0.3 1.3 1 0 0 1 1 1 1 HD domain zf-C2H2 PF00096.26 KNZ72430.1 - 1.2e-10 41.2 7.5 9.4e-05 22.7 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ72430.1 - 4.4e-06 26.9 2.3 4.4e-06 26.9 2.3 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ72430.1 - 1.3e-05 25.6 6.8 0.0097 16.7 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KNZ72430.1 - 0.4 11.3 1.0 21 5.8 0.0 2.6 1 1 1 2 2 2 0 FOXP coiled-coil domain Cytomega_UL20A PF05984.12 KNZ72430.1 - 2.7 8.3 6.1 8.2 6.8 1.6 3.1 3 0 0 3 3 3 0 Cytomegalovirus UL20A protein MMR_HSR1 PF01926.23 KNZ72432.1 - 9.6e-14 51.4 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ72432.1 - 0.00061 19.3 0.0 0.00089 18.8 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KNZ72432.1 - 0.0047 17.0 0.0 0.19 11.7 0.0 2.1 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 KNZ72432.1 - 0.06 12.7 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 KNZ72432.1 - 0.16 11.8 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Tmemb_170 PF10190.9 KNZ72433.1 - 9.2e-09 35.6 2.7 1.8e-06 28.2 0.6 2.1 2 0 0 2 2 2 2 Putative transmembrane protein 170 TEA PF01285.18 KNZ72434.1 - 7.4e-22 77.2 0.0 1.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain WD40 PF00400.32 KNZ72435.1 - 1e-33 114.8 17.9 2.3e-08 34.6 0.7 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72435.1 - 3.1e-11 43.4 0.3 0.029 14.7 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ72435.1 - 0.00029 19.6 5.3 0.14 10.8 0.1 3.2 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ72435.1 - 0.00093 18.2 1.8 2.7 6.9 1.3 3.1 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ72435.1 - 0.0017 18.3 0.1 1.3 8.9 0.1 3.1 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.12 KNZ72435.1 - 0.0088 15.7 0.2 0.062 12.9 0.0 2.2 1 1 1 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Kelch_6 PF13964.6 KNZ72435.1 - 0.038 14.3 0.1 3.7 8.0 0.1 2.9 2 0 0 2 2 2 0 Kelch motif RabGAP-TBC PF00566.18 KNZ72436.1 - 4.7e-50 170.2 0.0 7.4e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KNZ72436.1 - 6.7e-06 26.0 0.0 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 KNZ72436.1 - 0.00011 22.5 1.8 0.0012 19.2 0.2 3.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 KNZ72436.1 - 0.00028 20.6 4.7 0.0023 17.7 0.2 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KNZ72436.1 - 0.00033 20.0 3.1 0.00097 18.5 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KNZ72436.1 - 0.00075 19.3 0.6 0.13 12.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KNZ72436.1 - 0.045 13.3 0.1 0.23 11.0 0.0 2.3 2 0 0 2 2 2 0 EF hand HEPN_Swt1 PF18731.1 KNZ72436.1 - 0.048 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Swt1-like HEPN SPARC_Ca_bdg PF10591.9 KNZ72436.1 - 0.054 13.8 0.1 0.17 12.2 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region 2-oxoacid_dh PF00198.23 KNZ72440.1 - 7e-49 166.4 0.0 1.4e-48 165.4 0.0 1.5 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KNZ72440.1 - 2.5e-17 62.4 0.1 4.6e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KNZ72440.1 - 2.6e-12 46.9 0.3 5e-12 45.9 0.3 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KNZ72440.1 - 0.0025 17.6 0.2 0.0061 16.4 0.2 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.6 KNZ72440.1 - 0.12 13.1 0.0 0.28 11.9 0.0 1.6 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_D23 PF16576.5 KNZ72440.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Abhydrolase_1 PF00561.20 KNZ72441.1 - 6.8e-36 124.2 0.0 3.2e-35 122.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.25 KNZ72442.1 - 2.8e-26 92.2 1.2 2e-25 89.4 1.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ72442.1 - 6.3e-14 52.1 0.6 8.1e-12 45.2 0.6 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ72442.1 - 9.5e-07 28.9 3.0 3.2e-06 27.2 0.8 2.1 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KNZ72442.1 - 2.3e-05 24.0 0.0 0.082 12.3 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DFP PF04127.15 KNZ72442.1 - 0.0075 16.1 1.3 0.13 12.1 1.3 2.1 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Shikimate_DH PF01488.20 KNZ72442.1 - 0.048 13.7 0.2 0.11 12.5 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 KNZ72442.1 - 0.054 12.8 0.2 0.25 10.6 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding_3 PF13727.6 KNZ72442.1 - 0.064 13.3 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 CoA-binding domain Pyr_redox_2 PF07992.14 KNZ72442.1 - 0.086 12.1 1.3 0.16 11.2 1.3 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.13 KNZ72442.1 - 0.093 12.7 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_10 PF13460.6 KNZ72442.1 - 0.12 12.2 1.6 0.98 9.3 1.0 2.2 2 1 0 2 2 2 0 NAD(P)H-binding PAPA-1 PF04795.12 KNZ72443.1 - 7.9e-12 45.8 17.9 7.9e-12 45.8 17.9 4.0 2 2 0 2 2 2 1 PAPA-1-like conserved region DUF4746 PF15928.5 KNZ72443.1 - 5.7 6.3 25.1 0.17 11.3 5.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4746) UbiA PF01040.18 KNZ72446.1 - 1.7e-43 148.7 13.5 2.3e-43 148.3 13.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RVP_2 PF08284.11 KNZ72446.1 - 9.3e-05 22.2 0.2 0.00015 21.5 0.2 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease NTF2 PF02136.20 KNZ72447.1 - 3.8e-17 63.0 0.1 5.6e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 KNZ72447.1 - 2.4e-06 27.3 0.0 4.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Het-C PF07217.11 KNZ72448.1 - 3e-183 610.4 0.0 2.9e-112 376.0 0.0 2.0 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C SH3_15 PF18346.1 KNZ72448.1 - 0.044 14.1 0.2 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain HAUS2 PF15003.6 KNZ72448.1 - 0.19 11.4 0.1 0.36 10.5 0.1 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 CRIM PF16978.5 KNZ72450.1 - 0.072 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain WD40 PF00400.32 KNZ72451.1 - 3.5e-13 49.8 7.1 0.00011 22.9 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72451.1 - 1.4e-06 28.5 0.1 2.5 8.5 0.0 4.0 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ72451.1 - 0.002 18.0 0.2 12 6.0 0.0 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat HECT_2 PF09814.9 KNZ72452.1 - 2.2e-44 151.9 0.0 4.3e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DLH PF01738.18 KNZ72453.1 - 5.7e-16 58.7 0.0 4e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KNZ72453.1 - 0.11 13.0 0.0 0.18 12.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ72453.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KNZ72454.1 - 1.5e-20 73.7 0.1 3.1e-17 62.9 0.1 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 KNZ72454.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Homoserine_dh PF00742.19 KNZ72456.1 - 2.8e-42 144.6 0.0 8.4e-42 143.0 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KNZ72456.1 - 3.1e-18 66.5 0.0 5.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain PHB_acc_N PF07879.11 KNZ72456.1 - 0.059 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain ADC PF06314.11 KNZ72457.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Histone PF00125.24 KNZ72459.1 - 1.4e-21 77.2 2.7 1.9e-21 76.8 2.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNZ72459.1 - 3.4e-05 24.1 0.1 3.4e-05 24.1 0.1 2.0 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KNZ72459.1 - 0.00029 21.3 0.0 0.00055 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 KNZ72459.1 - 0.034 14.2 0.3 0.041 13.9 0.3 1.1 1 0 0 1 1 1 0 YscO-like protein CENP-W PF15510.6 KNZ72459.1 - 0.054 13.7 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Bt_P21 PF05560.11 KNZ72459.1 - 0.087 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein Histone PF00125.24 KNZ72460.1 - 1.4e-17 64.3 0.0 1.6e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KNZ72460.1 - 4.2e-16 58.4 1.9 7.5e-16 57.6 1.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KNZ72460.1 - 2.1e-05 24.7 0.0 2.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cys_Met_Meta_PP PF01053.20 KNZ72461.1 - 3.3e-23 81.8 0.0 4.7e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KNZ72461.1 - 7.3e-06 25.4 0.0 1.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II CBS PF00571.28 KNZ72462.1 - 1.6e-15 57.3 0.5 0.00017 22.0 0.0 4.4 4 0 0 4 4 4 3 CBS domain CNH PF00780.22 KNZ72463.1 - 9.5e-12 45.1 0.0 1.6e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain SKG6 PF08693.10 KNZ72464.1 - 0.22 11.0 7.3 0.14 11.6 1.5 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Zn_clus PF00172.18 KNZ72465.1 - 1.8e-07 31.2 7.1 3.1e-07 30.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNZ72465.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Paralemmin PF03285.15 KNZ72465.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Paralemmin PPR_2 PF13041.6 KNZ72466.1 - 4.3e-08 33.2 0.0 0.38 11.0 0.0 3.8 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.6 KNZ72466.1 - 2.8e-05 24.1 0.0 0.03 14.4 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 KNZ72466.1 - 0.00023 21.2 0.0 6.3 7.3 0.0 4.3 5 0 0 5 5 5 2 PPR repeat ADP_PFK_GK PF04587.15 KNZ72466.1 - 0.071 11.7 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Pkinase PF00069.25 KNZ72467.1 - 1.3e-62 211.5 0.0 2.3e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72467.1 - 1.2e-30 106.7 0.0 2e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ72467.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family TSGP1 PF07771.11 KNZ72468.1 - 0.081 13.1 4.6 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Tick salivary peptide group 1 NAM-associated PF14303.6 KNZ72468.1 - 6 7.6 10.3 1.4 9.6 2.0 2.2 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain MMR_HSR1 PF01926.23 KNZ72469.1 - 5.3e-11 42.6 0.0 1.3e-10 41.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ72469.1 - 0.00055 19.9 0.0 0.0014 18.6 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KNZ72469.1 - 0.0031 17.0 0.0 0.008 15.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 KNZ72469.1 - 0.006 17.0 0.0 0.022 15.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KNZ72469.1 - 0.016 15.8 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 KNZ72469.1 - 0.024 14.1 0.0 0.098 12.1 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family IIGP PF05049.13 KNZ72469.1 - 0.05 12.7 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KNZ72469.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_UL47 PF03362.13 KNZ72469.1 - 0.14 10.9 0.2 0.21 10.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein MCM PF00493.23 KNZ72469.1 - 0.18 10.8 0.0 0.37 9.8 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 KNZ72469.1 - 0.2 11.2 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KNZ72469.1 - 0.23 11.5 1.3 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Dynamin family DUF202 PF02656.15 KNZ72470.1 - 6.2e-14 52.2 6.0 6.8e-14 52.1 0.6 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF202) DUF3333 PF11812.8 KNZ72470.1 - 2.9 8.1 0.0 2.9 8.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) zf-C3HC4_3 PF13920.6 KNZ72471.1 - 5.8e-12 45.3 5.3 6.4e-10 38.7 1.5 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ72471.1 - 5.3e-05 23.0 1.5 0.00024 20.9 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ72471.1 - 0.00032 21.0 5.4 0.0017 18.7 1.7 2.5 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 KNZ72471.1 - 0.0014 18.5 4.6 0.0014 18.5 4.6 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KNZ72471.1 - 0.003 17.5 2.4 0.026 14.5 0.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ72471.1 - 0.14 12.2 5.8 1.8 8.6 0.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DUF1644 PF07800.12 KNZ72471.1 - 0.16 12.0 0.3 0.35 10.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Ribosomal_L27A PF00828.19 KNZ72472.1 - 3.3e-21 76.3 0.0 4.8e-21 75.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 KNZ72473.1 - 1.3e-26 92.1 0.0 1.8e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KNZ72473.1 - 1.1e-11 44.0 0.0 1.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.11 KNZ72473.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Rio2, N-terminal ADH_N PF08240.12 KNZ72474.1 - 2.1e-27 95.1 2.9 4.1e-27 94.2 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ72474.1 - 4.1e-27 94.7 0.8 7.3e-27 93.9 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KNZ72474.1 - 0.00047 19.5 0.3 0.00076 18.8 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TOBE_2 PF08402.10 KNZ72474.1 - 0.07 13.3 0.1 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 TOBE domain ADH_zinc_N_2 PF13602.6 KNZ72474.1 - 0.076 14.1 0.0 0.12 13.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RNA_pol_3_Rpc31 PF11705.8 KNZ72475.1 - 5.7e-25 88.9 4.5 8.4e-25 88.3 4.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RRM_1 PF00076.22 KNZ72476.1 - 2e-15 56.3 0.1 4.3e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KNZ72476.1 - 1.2e-06 28.9 0.9 1.2e-06 28.9 0.9 2.2 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KNZ72476.1 - 0.0021 17.9 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif DNA_topoisoIV PF00521.20 KNZ72476.1 - 0.21 10.4 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A PPTA PF01239.22 KNZ72477.1 - 5.8e-42 140.3 12.4 3.3e-09 36.2 0.1 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Glyco_transf_20 PF00982.21 KNZ72478.1 - 8.7e-149 496.2 0.0 1.2e-148 495.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KNZ72478.1 - 2.2e-67 226.6 0.0 6e-67 225.2 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Cnd1_N PF12922.7 KNZ72479.1 - 3.5e-56 189.6 6.0 1.4e-55 187.7 0.0 4.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KNZ72479.1 - 2.3e-55 187.0 3.9 2.8e-51 173.8 0.2 3.6 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ72479.1 - 8.3e-06 26.1 0.4 0.23 11.9 0.0 5.0 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 KNZ72479.1 - 5.8e-05 23.0 1.2 5.6 7.5 0.1 6.4 6 0 0 6 6 6 1 HEAT repeat YtzH PF14165.6 KNZ72479.1 - 0.002 18.5 2.9 0.011 16.1 0.6 3.4 2 1 1 3 3 3 1 YtzH-like protein RTP1_C1 PF10363.9 KNZ72479.1 - 0.0055 16.9 4.1 2.5 8.3 0.1 3.5 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KNZ72479.1 - 0.01 14.4 12.0 0.042 12.4 0.3 4.1 3 2 2 5 5 5 0 Adaptin N terminal region PIP5K PF01504.18 KNZ72480.1 - 5.6e-102 340.6 0.0 1e-101 339.8 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SR-25 PF10500.9 KNZ72480.1 - 0.73 9.4 6.0 1.7 8.2 6.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PP2C PF00481.21 KNZ72481.1 - 8.3e-22 78.1 0.0 7.1e-21 75.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KNZ72481.1 - 0.0064 16.4 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Aconitase_B_N PF11791.8 KNZ72481.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Aconitate B N-terminal domain MFS_1 PF07690.16 KNZ72482.1 - 3.6e-29 101.8 22.3 1.3e-27 96.7 19.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ72482.1 - 1.5e-05 24.0 7.1 0.0075 15.2 0.0 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2269 PF10027.9 KNZ72482.1 - 0.0035 17.4 6.1 0.0035 17.4 6.1 2.1 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) Peptidase_M56 PF05569.11 KNZ72482.1 - 0.19 10.9 1.3 0.51 9.5 1.3 1.8 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2070 PF09843.9 KNZ72482.1 - 2 6.6 6.2 3.6 5.8 6.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RNase_H PF00075.24 KNZ72484.1 - 0.0078 16.4 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.6 KNZ72486.1 - 7.2e-08 32.3 0.3 1.4e-07 31.4 0.3 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KNZ72488.1 - 1.5e-05 25.2 0.1 2.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 RNase H Tetraspanin PF00335.20 KNZ72489.1 - 1.2e-08 34.9 11.1 1.8e-08 34.4 11.1 1.2 1 0 0 1 1 1 1 Tetraspanin family Methyltransf_2 PF00891.18 KNZ72490.1 - 8.2e-26 90.6 0.0 8.5e-25 87.3 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KNZ72490.1 - 0.00055 19.9 0.1 0.0016 18.4 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KNZ72490.1 - 0.059 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain WBP-1 PF11669.8 KNZ72490.1 - 0.18 12.4 0.0 0.38 11.4 0.0 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 ABC2_membrane PF01061.24 KNZ72491.1 - 5.3e-76 254.7 50.0 2.6e-43 147.9 17.7 3.8 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KNZ72491.1 - 1.1e-39 134.2 4.8 3.4e-29 100.6 0.2 3.5 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KNZ72491.1 - 5.9e-38 130.5 0.0 7.8e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KNZ72491.1 - 6.8e-13 49.0 0.0 1.6e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KNZ72491.1 - 1.1e-06 29.2 0.0 0.0005 20.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KNZ72491.1 - 4.3e-06 26.7 0.0 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 1 1 RsgA GTPase AAA_22 PF13401.6 KNZ72491.1 - 9.7e-06 25.9 0.0 0.035 14.4 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KNZ72491.1 - 2.1e-05 24.2 0.2 0.0011 18.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KNZ72491.1 - 4.4e-05 22.7 11.5 4.4e-05 22.7 11.5 3.7 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_33 PF13671.6 KNZ72491.1 - 0.00041 20.5 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KNZ72491.1 - 0.00057 19.9 0.1 0.063 13.2 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 KNZ72491.1 - 0.00058 19.4 0.0 0.27 10.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KNZ72491.1 - 0.00083 19.3 0.6 0.59 9.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 KNZ72491.1 - 0.00098 19.0 0.0 0.05 13.5 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_29 PF13555.6 KNZ72491.1 - 0.003 17.3 0.2 0.21 11.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KNZ72491.1 - 0.006 16.3 0.2 1 9.0 0.4 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KNZ72491.1 - 0.0063 16.1 0.1 0.58 9.7 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KNZ72491.1 - 0.014 15.4 0.1 0.38 10.8 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KNZ72491.1 - 0.026 15.1 0.0 5.3 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KNZ72491.1 - 0.034 14.2 0.0 0.62 10.2 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 KNZ72491.1 - 0.04 14.4 0.0 5.3 7.5 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KNZ72491.1 - 0.049 14.0 0.5 4.4 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3464 PF11947.8 KNZ72491.1 - 0.049 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 AAA_24 PF13479.6 KNZ72491.1 - 0.086 12.6 0.1 4.4 7.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KNZ72491.1 - 0.094 13.2 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ72491.1 - 0.14 12.5 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 KNZ72491.1 - 0.16 12.2 0.1 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 KNZ72491.1 - 0.16 11.2 0.0 5.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 KNZ72491.1 - 0.16 11.3 0.1 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 KNZ72491.1 - 0.19 12.2 0.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KNZ72491.1 - 0.2 11.4 0.1 5.2 6.8 0.2 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation T2SSE PF00437.20 KNZ72491.1 - 0.21 10.6 0.2 17 4.4 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein TMEM171 PF15471.6 KNZ72492.1 - 0.43 9.5 2.8 1.6 7.6 3.2 1.7 2 0 0 2 2 2 0 Transmembrane protein family 171 MAM33 PF02330.16 KNZ72493.1 - 1.6e-42 145.9 0.1 9.4e-39 133.6 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial glycoprotein Aldedh PF00171.22 KNZ72494.1 - 3.3e-83 279.7 0.0 4e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhzC-PhzF PF02567.16 KNZ72495.1 - 8.3e-42 143.6 0.1 9.5e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Apolipoprotein PF01442.18 KNZ72496.1 - 3.8e-06 26.9 3.5 0.0013 18.7 1.3 3.0 2 2 0 2 2 2 2 Apolipoprotein A1/A4/E domain Perilipin PF03036.16 KNZ72496.1 - 0.00071 18.7 13.4 0.00073 18.7 0.1 2.8 1 1 0 2 2 2 1 Perilipin family PLC-beta_C PF08703.10 KNZ72496.1 - 0.001 19.1 0.2 2.4 8.1 0.0 2.5 2 1 0 2 2 2 2 PLC-beta C terminal DUF4435 PF14491.6 KNZ72496.1 - 0.19 11.6 2.1 0.3 10.9 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) VBS PF08913.10 KNZ72496.1 - 0.32 11.5 5.0 0.34 11.3 3.6 1.8 2 0 0 2 2 2 0 Vinculin Binding Site HisKA_3 PF07730.13 KNZ72496.1 - 0.44 11.1 4.3 16 6.1 0.1 4.2 3 2 2 5 5 5 0 Histidine kinase DUF1664 PF07889.12 KNZ72496.1 - 0.44 10.6 3.1 0.51 10.4 1.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Mis14 PF08641.12 KNZ72496.1 - 0.76 10.1 5.4 1 9.7 0.1 3.1 3 1 0 3 3 3 0 Kinetochore protein Mis14 like WXG100 PF06013.12 KNZ72496.1 - 0.92 9.8 5.1 3.9 7.8 1.0 2.8 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF1769 PF08588.10 KNZ72498.1 - 3.6e-22 78.3 0.1 8.5e-22 77.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Autophagy_C PF10381.9 KNZ72498.1 - 0.15 11.6 0.6 0.27 10.8 0.1 1.6 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal SR-25 PF10500.9 KNZ72498.1 - 0.3 10.6 2.1 0.47 10.0 2.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein G-alpha PF00503.20 KNZ72499.1 - 8.8e-112 373.8 2.0 1e-111 373.6 2.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ72499.1 - 6.1e-15 55.1 0.1 2.8e-09 36.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ72499.1 - 0.00077 18.9 0.1 0.76 9.1 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KNZ72499.1 - 0.013 15.7 0.1 0.76 10.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KNZ72499.1 - 0.019 14.4 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SMP_C2CD2L PF18696.1 KNZ72499.1 - 0.11 12.4 0.3 0.28 11.0 0.1 1.7 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain AAA_29 PF13555.6 KNZ72499.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Aldo_ket_red PF00248.21 KNZ72501.1 - 6e-58 196.4 0.1 6.7e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FGAR-AT_linker PF18072.1 KNZ72501.1 - 3 8.5 4.8 1.3 9.6 0.2 2.7 3 0 0 3 3 3 0 Formylglycinamide ribonucleotide amidotransferase linker domain Copper-fist PF00649.18 KNZ72502.1 - 1.5e-14 53.2 2.1 1.5e-14 53.2 2.1 2.4 1 1 1 2 2 2 1 Copper fist DNA binding domain Ank_2 PF12796.7 KNZ72503.1 - 2e-15 57.1 0.1 1.4e-07 32.0 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ72503.1 - 1.1e-13 51.1 0.3 0.0003 21.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ72503.1 - 7.2e-13 48.8 0.1 2.8e-06 27.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ72503.1 - 7.3e-11 41.3 0.1 0.0071 16.8 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank PF00023.30 KNZ72503.1 - 1.8e-07 31.3 1.7 0.088 13.3 0.2 5.0 3 1 1 4 4 4 2 Ankyrin repeat Bd3614-deam PF14439.6 KNZ72503.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase UPF0172 PF03665.13 KNZ72505.1 - 1e-56 192.0 0.0 1.2e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) WD40 PF00400.32 KNZ72506.1 - 1.9e-25 88.6 8.6 9.8e-06 26.2 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72506.1 - 0.0017 18.6 0.0 0.033 14.5 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KNZ72506.1 - 0.03 13.9 0.5 1.1 8.8 0.2 2.8 2 1 1 3 3 3 0 PQQ-like domain WD40_like PF17005.5 KNZ72506.1 - 0.082 12.2 0.0 12 5.1 0.0 2.6 1 1 1 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 KNZ72506.1 - 0.087 11.5 0.0 2 7.0 0.0 2.2 1 1 0 1 1 1 0 Nup133 N terminal like KDZ PF18758.1 KNZ72510.1 - 3.6e-08 33.3 0.2 0.00027 20.6 0.1 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Hormone_4 PF00220.17 KNZ72510.1 - 0.1 12.6 2.4 0.57 10.3 2.4 2.4 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain AA_permease_2 PF13520.6 KNZ72511.1 - 1.1e-34 120.1 32.1 1.5e-33 116.3 30.3 2.7 1 1 1 2 2 2 2 Amino acid permease Fungal_trans PF04082.18 KNZ72512.1 - 5.6e-34 117.4 0.0 1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ72512.1 - 1.4e-06 28.3 13.2 3.7e-06 26.9 13.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sds3 PF08598.11 KNZ72513.1 - 1.6e-23 83.9 0.0 1.6e-23 83.9 0.0 2.0 3 0 0 3 3 3 1 Sds3-like DUF775 PF05603.12 KNZ72515.1 - 7.5e-53 179.0 0.0 1e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) VIT1 PF01988.19 KNZ72516.1 - 1.3e-65 221.3 4.2 1.6e-65 221.0 4.2 1.1 1 0 0 1 1 1 1 VIT family TENA_THI-4 PF03070.16 KNZ72517.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 TENA/THI-4/PQQC family p450 PF00067.22 KNZ72518.1 - 3.4e-35 121.7 0.0 1.4e-21 76.8 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 PNP_UDP_1 PF01048.20 KNZ72519.1 - 9.1e-37 126.5 0.0 1.2e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Plus-3 PF03126.18 KNZ72520.1 - 2.4e-35 121.4 0.4 5.5e-34 117.0 0.0 2.9 3 0 0 3 3 3 1 Plus-3 domain OPT PF03169.15 KNZ72521.1 - 3.2e-152 508.3 38.2 3.6e-152 508.2 38.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Helitron_like_N PF14214.6 KNZ72522.1 - 1e-13 51.9 0.6 2.4e-12 47.5 0.1 2.2 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus RFX5_N PF18326.1 KNZ72522.1 - 0.039 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 RFX5 N-terminal domain PIF1 PF05970.14 KNZ72523.1 - 1.5e-11 44.1 0.1 1.7e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF2013 PF09431.10 KNZ72524.1 - 4.4e-53 179.1 0.9 4.4e-53 179.1 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DUF5112 PF17139.4 KNZ72524.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Biotin_carb_N PF00289.22 KNZ72526.1 - 1.2e-24 87.0 0.0 2.5e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain CPSase_L_D2 PF02786.17 KNZ72526.1 - 2.1e-10 40.5 0.0 3.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 KNZ72526.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.22 KNZ72526.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DDE_1 PF03184.19 KNZ72527.1 - 1.3e-19 70.5 0.1 1.5e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease RUN PF02759.19 KNZ72527.1 - 0.076 13.0 0.0 0.085 12.8 0.0 1.1 1 0 0 1 1 1 0 RUN domain COesterase PF00135.28 KNZ72528.1 - 1.9e-84 284.4 0.1 2.8e-84 283.9 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ72528.1 - 0.0001 22.2 0.8 0.0025 17.7 0.2 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Anoctamin PF04547.12 KNZ72529.1 - 1.4e-102 343.9 5.5 1.4e-102 343.9 5.5 1.9 2 1 0 2 2 2 1 Calcium-activated chloride channel NiFe_hyd_3_EhaA PF17367.2 KNZ72529.1 - 4.2 7.6 8.6 0.7 10.1 0.4 3.2 3 0 0 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A p450 PF00067.22 KNZ72530.1 - 1.1e-69 235.4 0.0 1.4e-69 235.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.21 KNZ72531.1 - 8.4e-40 136.6 0.0 1.8e-39 135.5 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF5082 PF16888.5 KNZ72531.1 - 0.021 15.1 6.4 0.046 14.0 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4604 PF15377.6 KNZ72531.1 - 0.2 12.1 0.0 0.2 12.1 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4604) UQ_con PF00179.26 KNZ72532.1 - 1.3e-16 60.6 0.1 1.8e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thymidylate_kin PF02223.17 KNZ72533.1 - 1.8e-43 148.4 0.0 2.1e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KNZ72533.1 - 0.0013 19.0 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KNZ72533.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 CotJB PF12652.7 KNZ72533.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 CotJB protein Glyco_hydro_76 PF03663.14 KNZ72534.1 - 1.4e-28 100.5 17.5 8.8e-26 91.3 3.6 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 RhoGEF PF00621.20 KNZ72535.1 - 6.1e-35 121.1 0.0 9.7e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 KNZ72535.1 - 0.0011 19.5 0.0 0.0097 16.4 0.0 2.5 2 0 0 2 2 2 1 PH domain Pirin PF02678.16 KNZ72537.1 - 1.7e-26 92.3 1.0 2.8e-26 91.6 1.0 1.2 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 KNZ72537.1 - 4.9e-09 35.8 0.5 6.2e-06 25.8 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 KNZ72537.1 - 7.4e-07 29.3 0.7 3.3e-05 24.0 0.3 2.9 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain Cupin_3 PF05899.12 KNZ72537.1 - 0.0091 15.7 0.3 0.27 10.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Dyp_perox PF04261.12 KNZ72538.1 - 0.00075 18.6 0.8 0.033 13.2 0.1 2.9 2 1 0 2 2 2 1 Dyp-type peroxidase family Glyco_transf_15 PF01793.16 KNZ72539.1 - 2.3e-54 184.8 3.5 2.9e-54 184.5 3.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DEAD PF00270.29 KNZ72541.1 - 7.9e-48 162.5 0.0 2e-47 161.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ72541.1 - 2.1e-30 105.3 0.0 6.9e-30 103.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ72541.1 - 0.022 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNZ72541.1 - 0.045 12.9 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GATA PF00320.27 KNZ72543.1 - 1.1e-09 37.7 4.5 4.7e-08 32.5 4.5 2.3 1 1 0 1 1 1 1 GATA zinc finger RVP_2 PF08284.11 KNZ72544.1 - 0.032 14.0 0.4 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease APH PF01636.23 KNZ72545.1 - 0.00015 21.7 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72545.1 - 0.00061 19.2 0.0 0.00093 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ72545.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ72547.1 - 4.6e-05 23.4 0.1 0.00012 22.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72547.1 - 0.0026 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF383 PF04063.14 KNZ72549.1 - 8.7e-60 201.6 0.0 1.9e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KNZ72549.1 - 6.9e-20 70.7 0.1 1.3e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_EZ PF13513.6 KNZ72549.1 - 0.072 13.6 0.0 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat Spt20 PF12090.8 KNZ72551.1 - 5e-27 95.0 0.0 1.1e-13 51.4 0.0 5.9 3 2 1 5 5 5 2 Spt20 family Fis1_TPR_C PF14853.6 KNZ72553.1 - 0.015 15.4 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 KNZ72553.1 - 0.023 14.8 0.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_15 PF01793.16 KNZ72554.1 - 1.1e-58 199.0 5.0 1.8e-58 198.4 5.0 1.3 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase HAT PF02184.16 KNZ72554.1 - 5.9e-19 67.7 58.4 1.3e-07 31.5 1.7 13.8 16 1 0 16 16 15 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KNZ72554.1 - 8.1e-19 66.7 28.6 0.0059 17.3 0.1 11.6 6 3 8 14 14 14 6 Tetratricopeptide repeat Suf PF05843.14 KNZ72554.1 - 3.7e-17 63.3 7.9 4.1e-05 23.7 0.1 6.7 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KNZ72554.1 - 2.1e-12 47.3 1.1 0.089 13.3 0.0 7.2 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ72554.1 - 5e-11 41.8 3.8 0.085 13.0 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ72554.1 - 4.8e-07 29.3 18.6 0.035 13.3 0.1 5.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ72554.1 - 6.2e-06 26.8 14.0 0.45 11.2 0.0 7.0 5 2 2 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72554.1 - 1.1e-05 25.5 0.2 0.095 13.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 KNZ72554.1 - 2e-05 24.2 2.9 0.0012 18.3 0.2 3.1 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 KNZ72554.1 - 2.9e-05 23.9 0.0 25 5.4 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ72554.1 - 3.1e-05 24.3 5.2 61 4.6 0.0 8.2 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72554.1 - 0.00076 19.6 4.0 1.1 9.5 0.2 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ72554.1 - 0.0012 18.6 0.0 5.6 7.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72554.1 - 0.0018 18.2 5.8 46 4.4 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72554.1 - 0.015 15.6 5.8 0.9 9.9 0.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ72554.1 - 0.015 15.0 0.1 4.7 7.0 0.0 3.9 4 0 0 4 4 4 0 TPR repeat U3_assoc_6 PF08640.11 KNZ72554.1 - 0.045 13.8 11.2 0.057 13.5 0.5 5.0 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 c-SKI_SMAD_bind PF08782.10 KNZ72554.1 - 1.1 9.5 4.0 1.4 9.2 0.3 3.0 4 0 0 4 4 3 0 c-SKI Smad4 binding domain Prefoldin PF02996.17 KNZ72556.1 - 0.089 12.7 0.2 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.8 KNZ72556.1 - 0.49 10.6 4.1 0.21 11.8 1.8 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding APH PF01636.23 KNZ72557.1 - 7.8e-06 26.0 0.0 2.4e-05 24.4 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72557.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ72557.1 - 0.014 14.9 0.0 0.056 13.0 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KNZ72557.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RdRP_2 PF00978.21 KNZ72557.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase adh_short PF00106.25 KNZ72558.1 - 1.9e-37 128.7 0.0 2.4e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ72558.1 - 1.4e-27 96.8 0.0 1.8e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ72558.1 - 9.4e-11 41.9 0.0 3.1e-10 40.2 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 KNZ72561.1 - 1.4e-15 57.3 0.0 1.7e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ72561.1 - 4.6e-07 29.6 0.0 5.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ72561.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 KR domain APH PF01636.23 KNZ72562.1 - 3e-05 24.1 0.0 8.8e-05 22.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72562.1 - 0.00043 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ72562.1 - 0.073 12.7 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KNZ72562.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RdRP_2 PF00978.21 KNZ72562.1 - 0.17 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase APH PF01636.23 KNZ72564.1 - 4.2e-05 23.6 0.1 0.00012 22.1 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72564.1 - 0.00023 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ72564.1 - 0.079 12.5 0.0 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KNZ72564.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RdRP_2 PF00978.21 KNZ72564.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase eIF3g PF12353.8 KNZ72565.1 - 0.0011 19.3 0.9 0.003 17.9 0.9 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2582 PF10771.9 KNZ72565.1 - 0.15 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) zf-C2HC5 PF06221.13 KNZ72566.1 - 1.3e-14 53.9 5.7 1.9e-14 53.4 5.7 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DZR PF12773.7 KNZ72566.1 - 0.88 9.6 5.4 1.6 8.8 5.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon HAUS6_N PF14661.6 KNZ72567.1 - 2.3e-07 30.6 3.3 0.00012 21.7 0.0 3.9 4 0 0 4 4 4 2 HAUS augmin-like complex subunit 6 N-terminus Amino_oxidase PF01593.24 KNZ72571.1 - 8.9e-72 242.8 0.0 1.2e-71 242.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ72571.1 - 6.6e-12 45.5 1.3 9e-12 45.1 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KNZ72571.1 - 0.00033 20.0 0.6 0.00055 19.3 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KNZ72571.1 - 0.00035 20.0 0.5 0.00059 19.3 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ72571.1 - 0.001 18.2 0.2 0.0015 17.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNZ72571.1 - 0.0017 18.0 1.5 0.0029 17.2 0.9 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ72571.1 - 0.002 17.4 0.1 0.011 14.9 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KNZ72571.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KNZ72571.1 - 0.03 13.0 0.1 0.05 12.3 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KNZ72571.1 - 0.062 13.9 0.4 0.15 12.6 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNZ72571.1 - 0.19 10.8 0.2 0.31 10.1 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A PTR2 PF00854.21 KNZ72576.1 - 4.1e-74 249.8 7.8 5.3e-74 249.4 7.8 1.1 1 0 0 1 1 1 1 POT family Retrotran_gag_2 PF14223.6 KNZ72580.1 - 8.4e-17 61.1 0.0 1.2e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ72580.1 - 0.0032 17.2 2.2 0.0061 16.3 2.2 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger DUF4219 PF13961.6 KNZ72580.1 - 0.011 15.4 0.2 0.023 14.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.23 KNZ72580.1 - 0.16 12.1 2.4 0.38 10.9 2.4 1.7 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 KNZ72580.1 - 0.18 12.2 0.4 0.3 11.5 0.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF3784 PF12650.7 KNZ72581.1 - 0.26 11.5 1.5 0.61 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF4407 PF14362.6 KNZ72583.1 - 0.07 12.5 0.1 0.096 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.22 KNZ72584.1 - 2.2e-61 208.0 0.0 3e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 THOC2_N PF16134.5 KNZ72585.1 - 0.16 10.5 0.1 0.81 8.2 0.0 1.8 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus FAM199X PF15814.5 KNZ72585.1 - 8.6 5.3 7.8 14 4.6 7.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X DSPc PF00782.20 KNZ72586.1 - 2.1e-40 137.6 0.2 1e-30 106.2 0.1 2.5 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KNZ72586.1 - 4.3e-05 23.8 0.1 0.0048 17.2 0.0 2.6 2 0 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KNZ72586.1 - 0.00041 20.0 0.0 0.00068 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KNZ72586.1 - 0.0016 18.2 0.1 0.0034 17.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) HU-CCDC81_bac_2 PF18175.1 KNZ72586.1 - 0.074 12.9 0.0 25 4.8 0.1 3.1 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 7TM_GPCR_Sri PF10327.9 KNZ72586.1 - 0.082 12.1 0.7 1.2 8.2 0.0 2.6 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri Myotub-related PF06602.14 KNZ72586.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain CDC24_OB3 PF17244.2 KNZ72587.1 - 0.065 12.9 0.2 0.092 12.4 0.2 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 HTH_21 PF13276.6 KNZ72589.1 - 0.017 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain SIR2 PF02146.17 KNZ72590.1 - 5.1e-23 81.9 0.1 6.3e-21 75.1 0.1 3.0 1 1 0 1 1 1 1 Sir2 family LIAS_N PF16881.5 KNZ72590.1 - 0.063 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family VirDNA-topo-I_N PF09266.10 KNZ72590.1 - 0.16 12.1 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Zn-ribbon_8 PF09723.10 KNZ72590.1 - 0.21 11.7 0.6 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 KNZ72591.1 - 6.8e-05 23.1 13.3 0.00049 20.4 2.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ72591.1 - 0.0018 18.6 2.9 0.0018 18.6 2.9 4.7 6 0 0 6 6 6 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ72591.1 - 0.014 16.2 2.3 0.014 16.2 2.3 4.3 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KNZ72591.1 - 8.8 7.0 10.0 0.27 11.9 0.6 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain Metallophos PF00149.28 KNZ72592.1 - 6.5e-36 124.7 0.9 2.8e-35 122.7 0.2 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase RT_RNaseH PF17917.1 KNZ72592.1 - 1.4e-18 67.1 0.8 2.6e-18 66.2 0.8 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72592.1 - 5.9e-09 35.9 0.0 1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase STPPase_N PF16891.5 KNZ72592.1 - 0.024 15.1 0.4 0.052 14.0 0.4 1.6 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KNZ72592.1 - 0.22 11.1 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain ABC_tran PF00005.27 KNZ72593.1 - 5.5e-46 156.5 0.0 1.6e-23 83.7 0.0 3.1 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KNZ72593.1 - 3e-21 75.2 5.6 7.6e-21 74.0 4.8 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KNZ72593.1 - 1.6e-12 47.9 6.3 0.031 14.1 0.2 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KNZ72593.1 - 2.2e-08 34.7 0.0 0.0003 21.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KNZ72593.1 - 2.5e-08 33.5 0.5 0.0022 17.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KNZ72593.1 - 1.4e-06 29.0 10.4 0.008 16.7 0.0 4.2 5 0 0 5 5 4 2 AAA domain NACHT PF05729.12 KNZ72593.1 - 4.7e-06 26.6 0.0 0.082 12.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 KNZ72593.1 - 6e-06 25.8 2.4 0.74 9.2 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 KNZ72593.1 - 4.3e-05 23.5 1.4 0.088 12.7 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase MMR_HSR1 PF01926.23 KNZ72593.1 - 0.00011 22.2 0.1 0.15 12.1 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_18 PF13238.6 KNZ72593.1 - 0.00018 22.1 0.0 0.87 10.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KNZ72593.1 - 0.00029 20.7 15.1 0.2 11.3 0.1 4.9 3 2 1 4 4 4 1 AAA ATPase domain AAA_28 PF13521.6 KNZ72593.1 - 0.0003 21.1 0.0 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KNZ72593.1 - 0.00072 19.3 0.5 2.1 8.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KNZ72593.1 - 0.0011 19.4 0.1 5.6 7.4 0.1 4.3 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ72593.1 - 0.0011 19.2 0.0 2.1 8.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KNZ72593.1 - 0.0025 17.9 4.6 1.2 9.2 0.7 3.5 3 1 1 4 4 4 2 Helicase HerA, central domain RNA_helicase PF00910.22 KNZ72593.1 - 0.0026 18.1 2.9 4.5 7.7 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 KNZ72593.1 - 0.0026 17.5 0.0 0.46 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KNZ72593.1 - 0.0027 17.1 0.2 0.86 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.15 KNZ72593.1 - 0.0058 16.6 0.9 1.2 9.0 0.1 3.2 3 0 0 3 3 3 1 NTPase AAA_5 PF07728.14 KNZ72593.1 - 0.0066 16.5 0.1 6.6 6.7 0.1 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KNZ72593.1 - 0.0077 16.4 0.0 4.5 7.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KNZ72593.1 - 0.017 15.2 8.6 1.1 9.3 0.1 4.2 2 2 1 3 3 3 0 Dynamin family Roc PF08477.13 KNZ72593.1 - 0.022 15.0 0.0 12 6.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KNZ72593.1 - 0.023 13.3 2.8 1.6 7.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.22 KNZ72593.1 - 0.034 13.3 0.0 8.4 5.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 KNZ72593.1 - 0.04 13.6 0.1 2.9 7.5 0.0 2.6 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 KNZ72593.1 - 0.052 12.7 2.0 3.6 6.7 0.0 3.0 3 1 0 3 3 3 0 G-protein alpha subunit AAA_25 PF13481.6 KNZ72593.1 - 0.072 12.6 0.1 6.7 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 KNZ72593.1 - 0.088 12.4 0.2 13 5.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 KNZ72593.1 - 0.1 13.0 0.6 16 5.9 0.0 4.0 4 1 0 4 4 4 0 AAA domain DAP3 PF10236.9 KNZ72593.1 - 0.15 11.2 3.0 7.8 5.6 0.1 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.17 KNZ72593.1 - 0.18 11.6 1.3 6.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 KNZ72593.1 - 0.76 9.4 4.0 82 2.8 0.0 3.8 4 0 0 4 4 4 0 Thymidylate kinase UPF0147 PF03685.13 KNZ72596.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) zinc_ribbon_10 PF10058.9 KNZ72597.1 - 2.1e-20 72.2 0.5 3.4e-20 71.5 0.5 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein zf-4CXXC_R1 PF10497.9 KNZ72597.1 - 0.043 14.0 0.1 0.091 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ZnuA PF01297.17 KNZ72597.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic PhnA_Zn_Ribbon PF08274.12 KNZ72597.1 - 0.85 9.6 2.8 4.4 7.3 2.9 1.9 1 1 1 2 2 2 0 PhnA Zinc-Ribbon DSPc PF00782.20 KNZ72598.1 - 1.4e-38 131.7 0.0 1.2e-30 106.0 0.0 3.0 2 1 1 3 3 3 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KNZ72598.1 - 0.00018 21.8 0.1 0.013 15.8 0.1 2.5 2 1 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KNZ72598.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPn PF14671.6 KNZ72598.1 - 0.054 13.9 0.2 7.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Dual specificity protein phosphatase, N-terminal half HTH_38 PF13936.6 KNZ72600.1 - 2.4e-10 40.0 1.5 4e-10 39.3 1.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1804 PF08822.11 KNZ72600.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) GerE PF00196.19 KNZ72600.1 - 0.024 14.2 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family MarR_2 PF12802.7 KNZ72600.1 - 0.027 14.4 0.1 0.06 13.2 0.1 1.7 2 0 0 2 2 2 0 MarR family HTH_23 PF13384.6 KNZ72600.1 - 0.03 14.1 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Sigma54_DBD PF04552.13 KNZ72600.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54, DNA binding domain HTH_37 PF13744.6 KNZ72600.1 - 0.12 12.4 0.0 4.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_38 PF13936.6 KNZ72601.1 - 2.9e-06 26.9 1.5 5.3e-06 26.1 1.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 KNZ72601.1 - 0.37 10.4 1.5 0.45 10.2 0.4 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain FPP PF05911.11 KNZ72603.1 - 0.013 13.8 7.1 0.019 13.2 7.1 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Glyco_hydro_63N PF16923.5 KNZ72603.1 - 0.072 13.2 0.5 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 N-terminal domain Atrophin-1 PF03154.15 KNZ72603.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family SlyX PF04102.12 KNZ72603.1 - 0.54 10.9 5.1 15 6.3 0.0 3.8 3 1 0 4 4 4 0 SlyX Spectrin PF00435.21 KNZ72603.1 - 0.8 10.2 7.6 2.8 8.5 5.5 2.3 2 0 0 2 2 2 0 Spectrin repeat RRP7 PF12923.7 KNZ72603.1 - 0.84 9.8 5.4 0.11 12.6 0.9 1.8 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain AAA_13 PF13166.6 KNZ72603.1 - 1.4 7.4 9.9 2.3 6.7 9.9 1.2 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 KNZ72603.1 - 5.8 7.1 10.1 0.76 9.9 0.9 2.9 3 0 0 3 3 3 0 Hr1 repeat DUF5082 PF16888.5 KNZ72603.1 - 6 7.2 10.2 5.5 7.3 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DivIC PF04977.15 KNZ72603.1 - 6.7 6.6 9.1 14 5.5 1.8 3.6 3 0 0 3 3 3 0 Septum formation initiator DUF4226 PF10774.9 KNZ72604.1 - 0.07 13.4 1.3 0.18 12.1 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Spc7 PF08317.11 KNZ72604.1 - 0.1 11.5 7.9 0.14 11.0 7.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GPO PF05929.11 KNZ72604.1 - 0.11 12.1 4.3 0.33 10.5 4.0 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase ROF PF07073.12 KNZ72604.1 - 0.19 11.9 3.5 0.16 12.2 1.7 1.7 1 1 1 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) UPF0242 PF06785.11 KNZ72604.1 - 0.35 10.9 8.3 0.44 10.6 8.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MCU PF04678.13 KNZ72604.1 - 0.4 10.8 2.2 0.62 10.1 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Integrase_H2C2 PF17921.1 KNZ72605.1 - 0.012 15.8 2.0 0.039 14.0 2.0 2.0 1 0 0 1 1 1 0 Integrase zinc binding domain Aa_trans PF01490.18 KNZ72606.1 - 7.6e-16 57.8 23.4 2e-15 56.4 23.4 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5515 PF17635.2 KNZ72606.1 - 0.095 13.4 0.0 0.21 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5515) Thiolase_N PF00108.23 KNZ72607.1 - 6e-05 22.5 0.0 7.3e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain SSF PF00474.17 KNZ72608.1 - 5.1e-24 84.9 35.1 5.1e-24 84.9 35.1 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.9 KNZ72608.1 - 0.15 10.8 0.0 0.15 10.8 0.0 3.9 3 2 1 4 4 4 0 Predicted membrane protein (DUF2207) Ferritin_2 PF13668.6 KNZ72609.1 - 1.1e-31 109.8 0.1 1.8e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Metallophos PF00149.28 KNZ72610.1 - 2.2e-14 54.5 1.5 3.7e-14 53.7 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ72610.1 - 1.1e-06 28.9 0.3 8.3e-05 22.8 0.3 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThylakoidFormat PF11264.8 KNZ72610.1 - 0.036 13.7 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein FA_desaturase PF00487.24 KNZ72611.1 - 9.3e-25 87.9 25.7 9.3e-25 87.9 25.7 1.4 2 0 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 KNZ72611.1 - 0.003 17.8 0.1 0.0055 16.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 KNZ72612.1 - 4.6e-23 82.4 31.1 6.8e-23 81.8 31.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KNZ72612.1 - 4.4e-05 23.7 0.0 8.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF2235 PF09994.9 KNZ72614.1 - 1.4e-95 319.9 0.0 1.8e-95 319.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) ketoacyl-synt PF00109.26 KNZ72615.1 - 9.6e-78 261.2 0.0 2.2e-77 260.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KNZ72615.1 - 4.4e-43 148.0 0.0 6.1e-42 144.2 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KNZ72615.1 - 2.5e-38 130.7 0.4 5.9e-38 129.5 0.1 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SAT PF16073.5 KNZ72615.1 - 3.6e-27 95.6 3.1 4.7e-25 88.7 0.1 3.1 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PS-DH PF14765.6 KNZ72615.1 - 1.3e-26 93.5 0.0 2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KNZ72615.1 - 3.5e-17 63.3 0.3 9.2e-16 58.6 0.0 3.0 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 KNZ72615.1 - 6.4e-13 48.9 0.8 1.7e-12 47.5 0.8 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 KNZ72615.1 - 1.5e-09 38.8 4.1 2.5e-07 31.5 0.1 3.4 3 1 1 4 4 4 2 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KNZ72615.1 - 9.6e-06 26.0 0.0 2.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KNZ72615.1 - 0.0074 15.7 0.2 0.019 14.3 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.7 KNZ72616.1 - 0.22 11.3 9.5 7e+02 -0.1 0.0 8.3 2 1 12 14 14 14 0 Alpha/beta hydrolase family Paramecium_SA PF01508.16 KNZ72616.1 - 8.2 6.9 21.5 1 9.8 3.8 2.6 2 1 1 3 3 3 0 Paramecium surface antigen domain CN_hydrolase PF00795.22 KNZ72622.1 - 3.2e-38 131.6 0.0 4.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KNZ72622.1 - 1.3e-22 80.1 0.0 5.8e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Sec6 PF06046.13 KNZ72623.1 - 1.4e-146 489.2 1.9 1.4e-146 489.2 1.9 1.9 2 0 0 2 2 2 1 Exocyst complex component Sec6 HECT PF00632.25 KNZ72623.1 - 0.0026 17.3 0.1 0.0046 16.5 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RPN7 PF10602.9 KNZ72623.1 - 0.015 15.0 1.0 0.043 13.5 1.0 1.8 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Fes1 PF08609.10 KNZ72623.1 - 0.048 14.5 3.2 0.19 12.6 2.0 2.8 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 Fib_alpha PF08702.10 KNZ72623.1 - 3.5 7.8 6.9 2.1 8.5 0.6 3.3 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family FAD_binding_3 PF01494.19 KNZ72624.1 - 1.7e-22 80.2 0.1 1.3e-12 47.6 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KNZ72624.1 - 3.2e-08 33.0 0.1 7.4e-05 22.0 0.1 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein Trp_halogenase PF04820.14 KNZ72624.1 - 0.00021 20.3 0.3 0.007 15.3 0.1 2.7 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 KNZ72624.1 - 0.00037 19.6 0.0 0.00056 19.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 KNZ72624.1 - 0.00047 19.5 0.1 0.0013 18.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ72624.1 - 0.00064 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KNZ72624.1 - 0.0019 18.2 0.0 0.0054 16.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KNZ72624.1 - 0.014 15.0 1.5 0.034 13.7 1.4 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ72624.1 - 0.02 15.1 0.2 0.059 13.6 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KNZ72624.1 - 0.043 12.5 0.0 0.092 11.4 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KNZ72624.1 - 0.045 12.8 1.0 0.084 11.9 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KNZ72624.1 - 0.13 12.9 0.2 1.3 9.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ72624.1 - 0.2 10.9 0.1 0.35 10.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 KNZ72625.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 F-box-like HAUS4 PF14735.6 KNZ72626.1 - 1.8e-07 31.1 1.3 0.0001 22.1 0.1 2.2 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 4 COG5 PF10392.9 KNZ72626.1 - 0.029 14.5 0.9 0.079 13.1 0.9 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Na_H_Exchanger PF00999.21 KNZ72629.1 - 4.2e-57 193.7 28.5 5.2e-57 193.4 28.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2649 PF10854.8 KNZ72629.1 - 0.7 10.2 5.1 0.11 12.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) Romo1 PF10247.9 KNZ72629.1 - 1.4 9.3 5.8 0.39 11.1 0.5 2.8 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Integrase_H2C2 PF17921.1 KNZ72630.1 - 0.016 15.3 3.0 0.016 15.3 3.0 1.9 2 0 0 2 2 2 0 Integrase zinc binding domain POT1PC PF16686.5 KNZ72630.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Subtilosin_A PF11420.8 KNZ72630.1 - 0.66 10.0 6.3 0.99 9.4 0.8 2.5 2 0 0 2 2 2 0 Bacteriocin subtilosin A Na_H_Exchanger PF00999.21 KNZ72634.1 - 1.5e-57 195.1 23.3 1.8e-57 194.8 23.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PHO4 PF01384.20 KNZ72634.1 - 0.34 9.9 2.6 0.24 10.4 0.5 1.7 1 1 0 1 1 1 0 Phosphate transporter family Romo1 PF10247.9 KNZ72634.1 - 1.2 9.6 6.1 0.29 11.5 0.7 2.8 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 MNHE PF01899.16 KNZ72634.1 - 1.2 8.9 10.4 1.8 8.3 1.2 3.0 3 0 0 3 3 3 0 Na+/H+ ion antiporter subunit DUF996 PF06195.13 KNZ72634.1 - 2.4 8.4 17.7 0.082 13.2 3.6 3.8 3 1 0 4 4 4 0 Protein of unknown function (DUF996) Ferlin_C PF16165.5 KNZ72635.1 - 0.052 13.5 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferlin C-terminus rve PF00665.26 KNZ72636.1 - 2.7e-06 27.5 0.0 5.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.23 KNZ72640.1 - 0.033 14.3 0.7 0.033 14.3 0.7 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ72640.1 - 0.042 13.6 0.6 0.074 12.8 0.6 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Na_H_Exchanger PF00999.21 KNZ72641.1 - 1.2e-57 195.5 29.1 1.5e-57 195.1 29.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2304 PF10066.9 KNZ72641.1 - 0.057 13.6 0.3 0.057 13.6 0.3 3.7 4 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2304) Mito_carr PF00153.27 KNZ72644.1 - 1.3e-28 98.8 9.0 1.3e-16 60.3 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein DHBP_synthase PF00926.19 KNZ72645.1 - 4.5e-89 297.1 0.1 5.2e-89 296.9 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase PS_Dcarbxylase PF02666.15 KNZ72646.1 - 4e-53 180.0 0.0 6.1e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase zf_CCCH_4 PF18345.1 KNZ72646.1 - 4.8e-31 105.9 91.0 1.4e-05 25.0 1.9 8.7 8 0 0 8 8 8 8 Zinc finger domain zf-CCCH PF00642.24 KNZ72646.1 - 6.4e-29 99.3 68.6 2e-05 24.4 3.7 8.5 8 0 0 8 8 8 8 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KNZ72646.1 - 1.9e-28 99.3 24.1 0.0013 19.4 0.1 8.8 7 2 1 8 8 8 8 Torus domain zf-CCCH_4 PF18044.1 KNZ72646.1 - 1e-22 79.4 78.7 5.9e-05 22.8 1.2 8.7 8 0 0 8 8 8 8 CCCH-type zinc finger GFO_IDH_MocA PF01408.22 KNZ72646.1 - 5.5e-19 69.2 0.0 1.4e-18 67.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold zf-CCCH_3 PF15663.5 KNZ72646.1 - 1.3e-05 25.4 30.6 0.51 10.6 0.0 7.6 7 1 0 7 7 7 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 KNZ72646.1 - 3.5e-05 24.1 72.1 0.025 15.0 3.8 8.2 8 0 0 8 8 8 5 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 KNZ72646.1 - 0.00055 20.0 5.3 0.0016 18.5 5.3 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KNZ72646.1 - 0.002 18.1 2.3 0.0069 16.4 2.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KNZ72646.1 - 0.0029 17.4 8.0 0.0075 16.1 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ72646.1 - 0.01 15.7 2.4 0.042 13.7 2.4 2.1 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KNZ72646.1 - 0.026 14.4 3.8 0.073 13.0 3.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KNZ72646.1 - 0.04 13.7 0.0 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ72646.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-C3HC4_2 PF13923.6 KNZ72646.1 - 0.16 11.9 5.4 0.58 10.0 5.4 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ72646.1 - 3.7 7.6 10.4 5.3 7.1 8.9 2.1 2 0 0 2 2 1 0 zinc-RING finger domain OHCU_decarbox PF09349.10 KNZ72647.1 - 7.3e-29 101.2 0.0 9.2e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DnaJ PF00226.31 KNZ72648.1 - 8.9e-21 73.8 1.6 2.5e-20 72.3 1.6 1.8 2 0 0 2 2 2 1 DnaJ domain Sigma70_ner PF04546.13 KNZ72648.1 - 0.025 14.5 5.0 0.66 9.8 5.0 2.2 1 1 0 1 1 1 0 Sigma-70, non-essential region RPT PF13446.6 KNZ72648.1 - 0.035 14.0 0.2 0.8 9.7 0.0 2.6 2 1 0 2 2 2 0 A repeated domain in UCH-protein Hrs_helical PF12210.8 KNZ72648.1 - 0.63 10.6 7.3 0.89 10.1 0.6 3.0 3 1 1 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pkinase PF00069.25 KNZ72649.1 - 1.5e-62 211.3 0.0 1.9e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72649.1 - 5.1e-30 104.6 0.0 6.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ72649.1 - 0.01 15.8 0.1 0.036 14.0 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ72649.1 - 0.014 14.4 0.0 0.29 10.0 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KNZ72649.1 - 0.037 13.3 0.0 0.11 11.8 0.0 1.7 1 1 1 2 2 2 0 Kinase-like zf-RanBP PF00641.18 KNZ72650.1 - 5.4e-07 28.8 15.6 4.5e-05 22.7 4.7 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KNZ72650.1 - 0.013 14.9 10.3 0.12 11.8 2.2 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PHD_2 PF13831.6 KNZ72650.1 - 0.032 13.8 1.3 1.7 8.3 0.1 2.7 2 0 0 2 2 2 0 PHD-finger Prok-RING_2 PF14445.6 KNZ72650.1 - 1.1 9.4 3.8 5.6 7.2 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-Sec23_Sec24 PF04810.15 KNZ72650.1 - 7.1 6.8 13.4 2 8.5 0.0 3.0 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger NADH-u_ox-rdase PF10785.9 KNZ72651.1 - 4.9e-33 113.7 0.2 8e-33 113.0 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KNZ72651.1 - 1.2e-12 47.6 0.0 1.7e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Transferase PF02458.15 KNZ72652.1 - 2.7e-27 95.5 0.0 1.6e-13 50.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family DPBB_1 PF03330.18 KNZ72653.1 - 0.00032 20.9 1.7 0.00044 20.5 0.3 1.9 1 1 1 2 2 2 1 Lytic transglycolase DHHC PF01529.20 KNZ72654.1 - 7.6e-20 71.4 5.5 3.7e-19 69.1 5.5 1.9 1 1 0 1 1 1 1 DHHC palmitoyltransferase Med4 PF10018.9 KNZ72655.1 - 6.5e-22 78.2 0.0 8.3e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CENP-H PF05837.12 KNZ72655.1 - 0.016 15.6 2.5 0.025 15.0 2.5 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4226 PF10774.9 KNZ72655.1 - 0.018 15.3 0.5 0.029 14.6 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Muted PF14942.6 KNZ72655.1 - 0.071 13.5 1.0 0.099 13.0 1.0 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein HTH_19 PF12844.7 KNZ72655.1 - 0.12 12.5 0.7 0.23 11.5 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Put_DNA-bind_N PF06971.13 KNZ72655.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus TRAF_BIRC3_bd PF16673.5 KNZ72655.1 - 0.5 10.2 3.9 0.27 11.1 1.0 1.9 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain ABC_tran_CTD PF16326.5 KNZ72655.1 - 0.53 10.6 13.6 0.076 13.3 2.0 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF5446 PF17522.2 KNZ72655.1 - 4.8 7.4 6.3 1.2 9.4 0.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Voltage_CLC PF00654.20 KNZ72656.1 - 2.2e-82 277.2 26.6 2.2e-82 277.2 26.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel DUF2408 PF10303.9 KNZ72657.1 - 9.8e-58 194.5 8.2 1.3e-41 142.3 0.1 5.0 4 1 0 4 4 4 3 Protein of unknown function (DUF2408) MscS_porin PF12795.7 KNZ72657.1 - 0.002 17.8 2.9 0.17 11.4 0.3 2.4 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain FUSC PF04632.12 KNZ72657.1 - 0.0042 15.7 0.2 0.0076 14.8 0.2 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein family Laminin_I PF06008.14 KNZ72657.1 - 0.034 13.8 5.0 0.27 10.9 0.2 2.7 2 1 0 2 2 2 0 Laminin Domain I DUF2968 PF11180.8 KNZ72657.1 - 0.33 10.5 3.1 0.34 10.5 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) V-SNARE PF05008.15 KNZ72657.1 - 0.54 10.7 0.1 0.54 10.7 0.1 3.5 5 1 1 6 6 6 0 Vesicle transport v-SNARE protein N-terminus NBD94 PF16830.5 KNZ72657.1 - 0.94 9.9 5.3 0.79 10.2 0.3 3.2 4 0 0 4 4 4 0 Nucleotide-Binding Domain 94 of RH BST2 PF16716.5 KNZ72657.1 - 1.4 9.6 7.5 29 5.3 2.1 4.4 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 Snapin_Pallidin PF14712.6 KNZ72657.1 - 1.7 9.1 14.4 11 6.5 0.3 5.4 6 1 0 6 6 6 0 Snapin/Pallidin Laminin_II PF06009.12 KNZ72657.1 - 5.1 7.1 6.9 42 4.1 0.7 3.8 4 0 0 4 4 4 0 Laminin Domain II Hrs_helical PF12210.8 KNZ72657.1 - 5.1 7.7 8.2 2.2 8.9 0.2 3.8 4 1 1 5 5 5 0 Hepatocyte growth factor-regulated tyrosine kinase substrate BLOC1_2 PF10046.9 KNZ72657.1 - 8.3 6.8 9.2 4.2 7.7 0.1 3.5 5 0 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KNZ72658.1 - 2.1e-44 151.2 33.7 2.6e-44 150.8 33.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KNZ72658.1 - 8e-08 31.9 32.5 0.00098 18.6 18.7 2.8 1 1 1 2 2 2 2 Tropomyosin Fez1 PF06818.15 KNZ72658.1 - 0.008 16.7 25.7 0.023 15.2 15.4 2.0 1 1 1 2 2 2 1 Fez1 HGD-D PF06050.13 KNZ72658.1 - 0.0091 15.8 3.3 0.0094 15.7 2.7 1.3 1 1 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component Flagellin_C PF00700.21 KNZ72658.1 - 0.016 15.6 5.3 0.22 11.9 0.7 2.5 2 1 1 3 3 2 0 Bacterial flagellin C-terminal helical region HHV-5_US34A PF17087.5 KNZ72658.1 - 0.031 14.4 1.7 0.031 14.4 1.7 2.2 2 1 1 3 3 3 0 Herpesvirus US34A protein family GAS PF13851.6 KNZ72658.1 - 0.19 11.1 32.3 8.8 5.6 31.8 2.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 KNZ72658.1 - 0.19 11.8 40.0 0.55 10.3 11.4 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 KNZ72658.1 - 0.42 10.4 27.4 0.48 10.2 12.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 KNZ72658.1 - 0.46 10.9 23.8 1.3 9.4 4.3 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) KELK PF15796.5 KNZ72658.1 - 0.57 10.7 28.8 0.083 13.4 6.0 3.3 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Jnk-SapK_ap_N PF09744.9 KNZ72658.1 - 0.68 10.1 36.0 0.44 10.8 17.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 KNZ72658.1 - 0.72 9.1 27.9 1.5 8.1 18.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BRE1 PF08647.11 KNZ72658.1 - 0.83 9.8 29.1 0.39 10.8 11.6 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 KNZ72658.1 - 0.9 9.6 29.9 0.91 9.6 22.2 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 KNZ72658.1 - 1.9 8.9 33.5 13 6.2 5.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 KNZ72658.1 - 1.9 8.6 38.1 11 6.1 14.1 3.0 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 KNZ72658.1 - 2.2 8.4 9.2 2 8.5 7.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 KNZ72658.1 - 3.2 6.5 29.8 2.1 7.2 25.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein MPDZ_u10 PF16667.5 KNZ72658.1 - 3.4 8.6 4.7 1.5 9.7 2.2 1.7 2 0 0 2 2 1 0 Unstructured region 10 on multiple PDZ protein PRKG1_interact PF15898.5 KNZ72658.1 - 4.2 8.3 24.8 1.7 9.6 14.2 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Fib_alpha PF08702.10 KNZ72658.1 - 5.2 7.3 14.6 5.6 7.1 0.9 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 KNZ72658.1 - 6.7 7.0 28.3 11 6.3 3.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.11 KNZ72658.1 - 7.2 4.4 8.8 7.6 4.3 8.8 1.1 1 0 0 1 1 1 0 Prominin XhlA PF10779.9 KNZ72658.1 - 9.6 6.5 17.5 1.2 9.4 1.0 3.7 1 1 2 3 3 3 0 Haemolysin XhlA CREPT PF16566.5 KNZ72658.1 - 9.7 6.3 21.4 3.4 7.8 8.3 2.8 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour SelR PF01641.18 KNZ72659.1 - 4e-53 178.6 0.1 4.6e-53 178.4 0.1 1.0 1 0 0 1 1 1 1 SelR domain ADD_ATRX PF17981.1 KNZ72659.1 - 0.0097 15.7 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 1 Cysteine Rich ADD domain DZR PF12773.7 KNZ72659.1 - 0.044 13.8 1.6 1.9 8.6 0.0 2.3 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KNZ72659.1 - 0.06 13.1 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Yippee-Mis18 PF03226.14 KNZ72659.1 - 0.074 13.3 0.3 0.23 11.7 0.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.6 KNZ72659.1 - 0.079 13.1 2.4 0.3 11.2 0.5 2.6 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.12 KNZ72659.1 - 0.21 11.1 1.9 1.4 8.5 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ACC PF17848.1 KNZ72659.1 - 0.52 10.4 2.3 1.7 8.8 0.3 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DNA_RNApol_7kD PF03604.13 KNZ72659.1 - 1.8 8.3 4.1 4.9 6.9 0.5 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.6 KNZ72659.1 - 3.6 7.1 7.6 11 5.6 0.2 3.1 4 0 0 4 4 4 0 zinc-ribbon domain IF4E PF01652.18 KNZ72660.1 - 1e-55 187.9 0.2 1.3e-55 187.5 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Macoilin PF09726.9 KNZ72660.1 - 0.067 11.7 0.0 0.092 11.3 0.0 1.2 1 1 0 1 1 1 0 Macoilin family EF-hand_11 PF08976.11 KNZ72660.1 - 0.14 13.1 0.0 0.41 11.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain Kei1 PF08552.11 KNZ72661.1 - 4e-54 183.4 5.2 7.3e-54 182.6 5.2 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 MFS_MOT1 PF16983.5 KNZ72661.1 - 0.014 15.8 1.6 0.029 14.7 1.6 1.5 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily PQ-loop PF04193.14 KNZ72662.1 - 7.5e-30 102.5 7.1 1.6e-17 63.0 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 KNZ72662.1 - 0.029 15.2 0.4 0.29 11.9 0.1 2.4 1 1 0 2 2 2 0 ER lumen protein retaining receptor MtN3_slv PF03083.16 KNZ72662.1 - 0.096 12.7 3.2 1.6 8.9 0.1 2.8 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange rve PF00665.26 KNZ72664.1 - 0.0018 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF3244 PF11589.8 KNZ72666.1 - 0.12 12.4 0.4 0.18 11.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Coatomer_WDAD PF04053.14 KNZ72668.1 - 3.3e-154 514.2 0.0 5.8e-154 513.4 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 KNZ72668.1 - 4.5e-37 125.4 5.8 1.7e-06 28.7 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72668.1 - 4.3e-09 36.5 0.2 0.007 16.6 0.0 5.8 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ72668.1 - 0.00077 18.2 0.2 0.39 9.3 0.0 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KNZ72668.1 - 0.00099 19.1 0.1 7.5 6.6 0.0 4.8 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region LigD_N PF13298.6 KNZ72668.1 - 0.061 13.6 0.1 5.6 7.3 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase Ligase (LigD) Nucleoporin_N PF08801.11 KNZ72668.1 - 0.16 10.7 0.2 0.95 8.1 0.0 2.5 4 0 0 4 4 4 0 Nup133 N terminal like Sugar_tr PF00083.24 KNZ72669.1 - 6.8e-132 440.5 18.8 7.7e-132 440.4 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ72669.1 - 5.1e-24 84.9 25.4 5.1e-24 84.9 25.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ThrE PF06738.12 KNZ72669.1 - 4.7 6.5 14.2 0.45 9.8 2.0 2.7 2 1 0 2 2 2 0 Putative threonine/serine exporter Abhydrolase_1 PF00561.20 KNZ72670.1 - 6.2e-19 68.6 0.1 1.1e-17 64.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ72670.1 - 1e-15 57.6 0.2 4.8e-15 55.5 0.2 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ72670.1 - 1.2e-15 58.7 0.7 2e-15 58.0 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KNZ72670.1 - 2.6e-06 27.1 0.1 0.00019 21.0 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KNZ72670.1 - 1.2e-05 25.3 0.1 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KNZ72670.1 - 0.0001 21.9 0.3 0.21 11.1 0.2 3.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 KNZ72670.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 KNZ72670.1 - 0.17 11.3 0.2 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase Hist_deacetyl PF00850.19 KNZ72672.1 - 8.6e-81 271.8 0.1 2e-80 270.5 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Peptidase_M24 PF00557.24 KNZ72674.1 - 2.9e-45 154.6 0.0 5.8e-45 153.5 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.9 KNZ72674.1 - 1.2e-39 136.0 0.0 1.4e-22 79.5 0.0 3.0 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 KNZ72674.1 - 9.2e-09 34.6 0.8 1.7e-08 33.7 0.8 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain XPC-binding PF09280.11 KNZ72674.1 - 0.29 10.9 2.2 0.61 9.9 0.5 2.5 2 0 0 2 2 2 0 XPC-binding domain adh_short PF00106.25 KNZ72675.1 - 7.5e-11 41.8 0.0 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ72675.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ72675.1 - 7.2e-07 29.3 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KNZ72675.1 - 0.0015 18.8 1.1 0.0021 18.3 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain BTB PF00651.31 KNZ72675.1 - 0.0058 16.8 1.1 0.011 15.9 0.5 1.7 2 0 0 2 2 2 1 BTB/POZ domain API5 PF05918.11 KNZ72675.1 - 0.14 11.0 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ham1p_like PF01725.16 KNZ72676.1 - 2.8e-39 135.0 0.0 3.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Phytochelatin PF05023.14 KNZ72677.1 - 0.11 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Phytochelatin synthase DUF1768 PF08719.11 KNZ72679.1 - 8.9e-21 74.8 0.0 1.4e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TAFII28 PF04719.14 KNZ72680.1 - 7.3e-34 115.7 0.1 1.1e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 KNZ72680.1 - 0.0022 18.2 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone fn3_2 PF16893.5 KNZ72681.1 - 5.2e-39 132.3 0.3 1.5e-38 130.8 0.3 1.8 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KNZ72681.1 - 3.7e-26 90.8 0.1 7.5e-26 89.8 0.1 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 KNZ72681.1 - 1.9e-06 28.1 0.0 3.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 KNZ72681.1 - 0.00038 20.7 0.4 0.002 18.5 0.4 2.2 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 KNZ72681.1 - 0.00067 19.8 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.7 KNZ72681.1 - 0.0011 18.8 0.0 0.011 15.7 0.0 2.2 1 1 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KNZ72681.1 - 0.032 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain eIF2A PF08662.11 KNZ72682.1 - 9.2e-39 133.3 0.2 2.4e-33 115.6 0.0 4.4 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KNZ72682.1 - 1.5e-06 28.0 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KNZ72682.1 - 0.004 18.0 3.1 3.4 8.7 0.1 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat Pkinase PF00069.25 KNZ72683.1 - 1.9e-63 214.3 0.0 2.3e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72683.1 - 6.5e-30 104.3 0.0 1.3e-29 103.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ72683.1 - 0.03 13.3 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KNZ72683.1 - 0.057 12.7 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Clathrin PF00637.20 KNZ72685.1 - 1.4e-25 89.9 0.1 3.9e-25 88.4 0.1 1.8 1 0 0 1 1 1 1 Region in Clathrin and VPS zf-RING_2 PF13639.6 KNZ72685.1 - 0.0058 16.9 2.1 0.0058 16.9 2.1 2.4 2 0 0 2 2 2 1 Ring finger domain Vps39_1 PF10366.9 KNZ72685.1 - 0.01 16.1 0.4 0.074 13.3 0.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KNZ72685.1 - 0.014 15.9 0.1 0.028 14.9 0.1 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-ANAPC11 PF12861.7 KNZ72685.1 - 0.3 11.2 2.0 0.43 10.7 0.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KNZ72685.1 - 0.36 10.5 2.0 0.77 9.4 2.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KNZ72685.1 - 0.97 9.5 5.0 1.5 8.8 3.7 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 KNZ72685.1 - 1.7 8.4 5.4 5.2 6.9 5.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KNZ72685.1 - 5.3 7.2 13.0 0.052 13.6 2.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNZ72685.1 - 5.9 6.8 8.6 0.48 10.3 2.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3446 PF11928.8 KNZ72685.1 - 8.3 6.8 8.7 10 6.5 0.1 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain TAF4 PF05236.14 KNZ72686.1 - 2.5e-34 119.3 5.4 3.8e-34 118.7 5.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family G_path_suppress PF15991.5 KNZ72686.1 - 0.0023 18.1 2.9 0.0023 18.1 2.9 2.6 2 2 0 2 2 2 1 G-protein pathway suppressor Sporozoite_P67 PF05642.11 KNZ72686.1 - 0.57 8.2 10.3 0.87 7.6 10.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L13 PF00572.18 KNZ72687.1 - 3.4e-52 176.0 0.1 4.3e-52 175.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 UAF_Rrn10 PF05234.11 KNZ72688.1 - 0.038 14.2 0.0 8.2 6.7 0.0 2.3 2 0 0 2 2 2 0 UAF complex subunit Rrn10 AAA_21 PF13304.6 KNZ72688.1 - 6.1 6.6 9.9 1.1 8.9 5.7 1.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TPR_2 PF07719.17 KNZ72689.1 - 3.9e-13 48.4 3.8 0.00056 19.8 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ72689.1 - 1.1e-10 40.8 1.1 0.02 14.7 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ72689.1 - 1.9e-10 40.3 0.2 0.02 14.6 0.0 4.5 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 KNZ72689.1 - 2.1e-08 34.7 2.0 0.00093 19.8 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72689.1 - 2.5e-08 34.1 5.2 0.0011 19.2 0.2 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72689.1 - 3.2e-08 33.2 0.3 0.039 14.2 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ72689.1 - 4.3e-08 33.5 0.0 0.036 14.6 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72689.1 - 8.8e-07 28.9 0.0 0.0066 16.7 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72689.1 - 1.9e-05 24.3 4.0 5.5 7.3 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ72689.1 - 0.00014 22.4 20.7 0.05 14.4 0.0 7.3 6 3 3 9 9 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72689.1 - 0.00017 21.7 9.9 0.0052 16.9 0.0 5.8 6 1 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ72689.1 - 0.0015 18.8 0.0 0.012 15.9 0.1 2.6 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 KNZ72689.1 - 0.038 13.7 0.3 0.42 10.3 0.1 2.9 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 KNZ72689.1 - 0.16 11.8 18.3 0.11 12.4 0.3 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Rab5ip PF07019.12 KNZ72691.1 - 8.5e-21 74.3 2.6 1.1e-20 74.0 2.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Semialdhyde_dhC PF02774.18 KNZ72692.1 - 6.2e-35 120.9 0.0 9.1e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KNZ72692.1 - 2.8e-29 102.0 0.0 7.2e-29 100.7 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KNZ72692.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNase_PH PF01138.21 KNZ72693.1 - 1.6e-28 99.9 0.0 3.6e-28 98.7 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SMC_N PF02463.19 KNZ72694.1 - 2e-19 69.9 0.0 4.2e-19 68.9 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNZ72694.1 - 1.9e-09 38.3 27.7 1.9e-09 38.3 27.7 6.3 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 KNZ72694.1 - 0.00082 19.2 11.6 0.00082 19.2 11.6 4.1 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 KNZ72694.1 - 0.02 14.6 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KNZ72694.1 - 0.068 13.0 1.1 0.68 9.7 0.3 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3618 PF12277.8 KNZ72694.1 - 0.23 11.7 6.8 4.2 7.7 0.1 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) 4HBT PF03061.22 KNZ72696.1 - 4.4e-06 26.9 0.4 7.9e-06 26.1 0.1 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 2OG-FeII_Oxy_2 PF13532.6 KNZ72697.1 - 4.9e-13 49.7 0.0 7.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 KNZ72697.1 - 0.17 12.4 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RVP_2 PF08284.11 KNZ72698.1 - 0.00024 20.9 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KNZ72698.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease MSP1b PF03429.13 KNZ72698.1 - 0.22 9.6 0.0 0.49 8.4 0.0 1.5 2 0 0 2 2 2 0 Major surface protein 1B Retrotran_gag_2 PF14223.6 KNZ72701.1 - 0.0029 17.3 0.1 0.015 15.0 0.1 1.9 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.8 KNZ72701.1 - 0.014 15.7 0.7 0.035 14.5 0.2 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF553 PF04473.12 KNZ72701.1 - 0.029 13.9 0.7 0.042 13.4 0.6 1.6 1 1 0 1 1 1 0 Transglutaminase-like domain CtIP_N PF10482.9 KNZ72701.1 - 0.039 14.0 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2582 PF10771.9 KNZ72701.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) SAP18 PF06487.12 KNZ72703.1 - 8.5e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_transf_52 PF07922.11 KNZ72703.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 52 RRM_3 PF08777.11 KNZ72704.1 - 0.00026 21.0 0.0 0.0013 18.8 0.0 2.0 1 1 0 1 1 1 1 RNA binding motif RRM_1 PF00076.22 KNZ72704.1 - 0.0067 16.2 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L4 PF00573.22 KNZ72704.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family EF_assoc_2 PF08356.12 KNZ72706.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 EF hand associated PSP PF04046.16 KNZ72706.1 - 0.028 14.3 0.1 0.07 13.0 0.1 1.6 1 0 0 1 1 1 0 PSP KDZ PF18758.1 KNZ72708.1 - 9.3e-10 38.5 0.1 1.6e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Flavodoxin_4 PF12682.7 KNZ72708.1 - 0.057 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin EF_assoc_2 PF08356.12 KNZ72709.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 EF hand associated DUF1768 PF08719.11 KNZ72710.1 - 5.5e-15 56.0 0.0 6.1e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ATG22 PF11700.8 KNZ72712.1 - 1.7e-105 353.4 21.0 3.2e-104 349.2 21.0 1.9 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KNZ72712.1 - 6.9e-08 31.8 43.6 3.2e-06 26.3 13.2 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily FUSC-like PF12805.7 KNZ72712.1 - 0.35 9.9 2.3 0.65 9.0 2.3 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Amidase PF01425.21 KNZ72713.1 - 1.5e-36 126.3 0.0 6.1e-32 111.2 0.0 2.2 2 0 0 2 2 2 2 Amidase DUF4939 PF16297.5 KNZ72715.1 - 0.0028 17.5 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) MRF_C1 PF13887.6 KNZ72716.1 - 0.057 12.6 0.1 0.17 11.1 0.1 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 CZB PF13682.6 KNZ72716.1 - 0.2 12.1 8.7 0.65 10.5 8.7 1.9 1 1 0 1 1 1 0 Chemoreceptor zinc-binding domain Cryptochrome_C PF12546.8 KNZ72716.1 - 0.44 11.1 7.4 0.17 12.5 1.1 2.7 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal MatP PF06303.12 KNZ72716.1 - 5 7.8 12.2 16 6.1 0.4 2.5 2 0 0 2 2 2 0 MatP N-terminal domain p450 PF00067.22 KNZ72717.1 - 0.00067 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 GST_N_3 PF13417.6 KNZ72718.1 - 9.3e-16 58.0 0.0 2.2e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ72718.1 - 1.3e-13 51.1 0.0 2.6e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KNZ72718.1 - 1.9e-06 28.1 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 KNZ72718.1 - 0.03 15.1 0.0 0.1 13.4 0.0 2.0 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain MLVIN_C PF18697.1 KNZ72720.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.6 1 1 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain PGA2 PF07543.12 KNZ72721.1 - 0.93 9.5 4.8 0.27 11.2 1.3 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 TPR_12 PF13424.6 KNZ72722.1 - 2.4e-60 200.7 32.4 2.1e-15 56.8 0.4 4.5 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ72722.1 - 2.2e-52 173.6 13.4 1e-09 37.9 0.1 6.9 8 0 0 8 8 6 6 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ72722.1 - 3.8e-12 45.6 5.3 0.28 11.9 0.2 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ72722.1 - 1.5e-09 37.2 13.3 1.1 9.6 0.1 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ72722.1 - 1.6e-09 37.1 12.8 0.76 9.7 0.1 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ72722.1 - 4.4e-09 36.2 18.1 0.00013 21.5 6.2 2.7 1 1 1 2 2 2 2 MalT-like TPR region Patatin PF01734.22 KNZ72722.1 - 7.6e-08 32.8 0.0 1.8e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_16 PF13432.6 KNZ72722.1 - 2.4e-07 31.3 7.5 0.061 14.0 0.2 4.9 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72722.1 - 8.7e-07 28.5 13.4 0.025 14.6 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72722.1 - 2.2e-05 24.5 6.6 0.051 14.0 0.1 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ72722.1 - 0.00027 21.4 17.8 2.1 8.9 0.1 5.5 1 1 5 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ72722.1 - 0.00047 19.4 0.0 0.0018 17.5 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_3 PF07720.12 KNZ72722.1 - 0.013 15.5 1.4 64 3.7 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat RPN6_C_helix PF18503.1 KNZ72722.1 - 0.02 14.6 4.9 26 4.7 0.0 5.3 5 0 0 5 5 5 0 26S proteasome subunit RPN6 C-terminal helix domain TPR_20 PF14561.6 KNZ72722.1 - 0.024 14.9 6.7 2.8 8.3 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72722.1 - 0.026 14.7 15.1 3 8.3 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF4648 PF15505.6 KNZ72722.1 - 0.028 15.3 0.0 17 6.4 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4648) TPR_14 PF13428.6 KNZ72722.1 - 0.03 15.1 14.0 32 5.7 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.29 KNZ72722.1 - 0.078 13.4 0.0 0.31 11.5 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KNZ72722.1 - 0.086 13.2 0.3 17 5.8 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 KNZ72722.1 - 0.13 11.8 0.3 0.4 10.2 0.0 2.0 2 0 0 2 2 1 0 P-loop containing dynein motor region DUF4054 PF13262.6 KNZ72722.1 - 0.32 11.0 6.5 55 3.9 0.2 4.9 1 1 5 6 6 6 0 Protein of unknown function (DUF4054) AAA_16 PF13191.6 KNZ72722.1 - 0.54 10.6 5.0 0.89 9.9 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain YbaB_DNA_bd PF02575.16 KNZ72722.1 - 0.94 9.7 8.0 77 3.6 0.5 4.4 3 1 1 4 4 4 0 YbaB/EbfC DNA-binding family RPN6_N PF18055.1 KNZ72722.1 - 5.7 7.3 9.3 27 5.2 1.8 3.5 2 1 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF3139 PF11337.8 KNZ72722.1 - 6.1 7.6 6.7 1.7 9.4 0.7 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3139) RT_RNaseH PF17917.1 KNZ72724.1 - 2.2e-08 34.4 0.0 7.2e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ72724.1 - 0.0001 22.3 0.0 0.00033 20.7 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Glyoxalase_4 PF13669.6 KNZ72724.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4168 PF13767.6 KNZ72727.1 - 0.28 12.4 5.1 0.75 11.0 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) SCHIP-1 PF10148.9 KNZ72728.1 - 0.036 13.7 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 RVP_2 PF08284.11 KNZ72729.1 - 0.049 13.4 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease p450 PF00067.22 KNZ72731.1 - 9.9e-55 186.1 0.1 2.5e-37 128.7 0.1 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF1771 PF08590.10 KNZ72731.1 - 0.054 13.9 0.1 0.59 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) TIP120 PF08623.10 KNZ72732.1 - 2.5e-54 183.5 1.8 2.5e-53 180.3 0.2 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KNZ72732.1 - 6e-11 41.6 27.4 0.24 11.7 0.0 12.0 14 0 0 14 14 12 2 HEAT repeat HEAT_2 PF13646.6 KNZ72732.1 - 1.1e-10 41.8 22.2 0.088 13.2 0.8 9.5 6 2 3 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 KNZ72732.1 - 8.7e-09 35.7 26.8 0.032 14.7 0.1 12.1 12 1 1 13 13 13 2 HEAT-like repeat MMS19_C PF12460.8 KNZ72732.1 - 4.6e-07 29.3 31.3 0.0095 15.1 0.4 6.0 4 2 3 7 7 7 4 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 KNZ72732.1 - 9.3e-07 29.4 0.2 10 6.8 0.0 7.3 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KNZ72732.1 - 2.7e-06 27.1 4.6 0.045 13.3 0.2 5.0 5 1 0 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 KNZ72732.1 - 0.0002 21.4 6.4 5.3 7.1 0.2 6.4 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KNZ72732.1 - 0.00037 20.4 4.4 0.0022 17.9 0.0 4.2 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KNZ72732.1 - 0.0021 17.6 8.1 0.39 10.2 0.0 4.8 4 2 1 5 5 5 1 Tti2 family ParcG PF10274.9 KNZ72732.1 - 0.045 13.9 4.6 5.9 7.0 0.0 4.8 6 0 0 6 6 6 0 Parkin co-regulated protein RTP1_C1 PF10363.9 KNZ72732.1 - 0.09 13.0 5.8 1.5 9.0 0.1 4.9 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 GP24_25 PF17388.2 KNZ72732.1 - 0.12 12.4 1.8 0.79 9.7 1.8 2.5 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 FliT PF05400.13 KNZ72732.1 - 0.69 10.8 2.9 2.6 8.9 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein FliT Pkinase PF00069.25 KNZ72734.1 - 9.2e-56 189.1 0.0 1.1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72734.1 - 1.4e-23 83.5 0.0 1.9e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ72734.1 - 3.1e-05 23.4 0.1 0.0001 21.7 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KNZ72734.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ72734.1 - 0.13 12.2 0.1 2.7 7.8 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family AAA PF00004.29 KNZ72736.1 - 6.9e-42 143.0 0.0 1.1e-41 142.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KNZ72736.1 - 6.3e-26 90.1 0.1 1.8e-25 88.7 0.1 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KNZ72736.1 - 7.4e-21 74.0 4.7 1.5e-20 73.0 4.7 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 KNZ72736.1 - 1.4e-07 31.2 0.0 5.1e-07 29.4 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KNZ72736.1 - 2.7e-06 27.9 0.1 0.00078 19.9 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KNZ72736.1 - 3e-06 27.5 1.1 0.0012 19.1 0.2 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KNZ72736.1 - 5.1e-06 26.3 0.0 9.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNZ72736.1 - 2.1e-05 24.5 0.0 0.00011 22.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KNZ72736.1 - 2.5e-05 24.3 0.1 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KNZ72736.1 - 3.7e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 KNZ72736.1 - 0.00048 19.4 0.0 0.0021 17.3 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KNZ72736.1 - 0.00074 18.8 0.0 0.0018 17.5 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_24 PF13479.6 KNZ72736.1 - 0.001 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNZ72736.1 - 0.0012 19.0 0.1 0.0035 17.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 KNZ72736.1 - 0.002 18.7 0.0 0.0051 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KNZ72736.1 - 0.0027 17.8 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KNZ72736.1 - 0.0047 16.5 0.1 0.8 9.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 KNZ72736.1 - 0.0047 16.3 0.1 1.6 8.0 0.0 2.3 1 1 1 2 2 2 1 KaiC RNA_helicase PF00910.22 KNZ72736.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KNZ72736.1 - 0.0082 15.6 0.0 1.8 7.9 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein AAA_17 PF13207.6 KNZ72736.1 - 0.026 14.9 0.1 0.076 13.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 KNZ72736.1 - 0.039 13.3 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Use1 PF09753.9 KNZ72736.1 - 0.048 13.4 0.7 0.19 11.4 1.1 1.7 2 0 0 2 2 2 0 Membrane fusion protein Use1 NACHT PF05729.12 KNZ72736.1 - 0.056 13.4 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 KNZ72736.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KNZ72736.1 - 0.065 12.7 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 KNZ72736.1 - 0.079 12.9 0.1 1.3 8.9 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KNZ72736.1 - 0.091 12.6 0.0 0.52 10.1 0.0 2.0 1 1 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KNZ72736.1 - 0.1 12.3 0.0 0.54 9.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 KNZ72736.1 - 0.1 11.8 0.0 2.8 7.2 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_7 PF12775.7 KNZ72736.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 KNZ72736.1 - 0.18 11.9 0.0 0.51 10.4 0.0 1.7 2 0 0 2 2 1 0 Torsin Viral_helicase1 PF01443.18 KNZ72736.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APH PF01636.23 KNZ72737.1 - 4.5e-06 26.7 0.0 8.6e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ72737.1 - 0.012 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.20 KNZ72737.1 - 0.02 14.5 0.0 0.059 13.0 0.0 1.7 1 1 1 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 KNZ72737.1 - 0.062 12.7 0.2 0.19 11.0 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L19e PF01280.20 KNZ72738.1 - 2.1e-60 202.9 11.3 2.1e-60 202.9 11.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 KNZ72738.1 - 0.007 16.1 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain Lant_dehydr_C PF14028.6 KNZ72738.1 - 0.01 15.4 1.2 0.011 15.3 0.7 1.4 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term FAF PF11250.8 KNZ72738.1 - 0.082 13.2 0.9 0.21 11.9 0.1 2.1 2 0 0 2 2 2 0 Fantastic Four meristem regulator MOZ_SAS PF01853.18 KNZ72739.1 - 1.2e-62 210.7 0.1 6.1e-62 208.4 0.0 1.9 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 KNZ72739.1 - 6.1e-14 51.4 5.6 7.2e-07 28.7 0.3 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 KNZ72739.1 - 6.1e-08 32.4 0.2 1.4e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KNZ72739.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ72739.1 - 0.039 14.2 0.0 0.093 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4834 PF16118.5 KNZ72739.1 - 0.11 13.5 0.0 17 6.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) AA_permease_2 PF13520.6 KNZ72740.1 - 8.6e-46 156.6 42.5 1e-45 156.4 42.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ72740.1 - 1.5e-09 37.0 41.1 3e-09 36.0 41.1 1.4 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 KNZ72741.1 - 1.9e-34 119.3 0.0 2.8e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72741.1 - 1.8e-11 43.8 0.0 2.8e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ72741.1 - 0.011 15.7 0.1 0.028 14.3 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ72741.1 - 0.024 14.0 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like tRNA-synt_His PF13393.6 KNZ72744.1 - 0.11 11.8 0.7 0.14 11.3 0.7 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-CCHC PF00098.23 KNZ72745.1 - 0.00037 20.4 13.4 0.012 15.7 5.8 4.1 5 1 0 5 5 5 2 Zinc knuckle DUF2085 PF09858.9 KNZ72747.1 - 0.045 14.2 0.4 0.061 13.8 0.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) zf-RVT PF13966.6 KNZ72747.1 - 0.063 14.0 2.4 0.083 13.6 2.1 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase p450 PF00067.22 KNZ72750.1 - 2e-65 221.4 0.0 1.4e-64 218.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 TrmO_C PF18389.1 KNZ72750.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 TrmO C-terminal domain YceG PF02618.16 KNZ72750.1 - 0.21 11.1 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 YceG-like family p450 PF00067.22 KNZ72751.1 - 1.4e-63 215.3 0.0 5.6e-38 130.9 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 TrmO_C PF18389.1 KNZ72751.1 - 0.034 14.2 0.1 0.1 12.7 0.1 1.8 1 0 0 1 1 1 0 TrmO C-terminal domain PH PF00169.29 KNZ72752.1 - 7.7e-06 26.4 0.0 1.9e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF515 PF04415.12 KNZ72753.1 - 0.066 11.6 2.3 0.089 11.2 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) WASH-7_mid PF14744.6 KNZ72753.1 - 0.16 11.1 2.0 0.21 10.6 2.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 DUF3772 PF12607.8 KNZ72753.1 - 1.7 8.5 3.7 5.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) BST2 PF16716.5 KNZ72753.1 - 2.2 8.9 6.1 4.2 8.0 5.4 1.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Glyco_transf_17 PF04724.13 KNZ72754.1 - 2e-139 464.5 0.3 2.3e-139 464.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_hydro_18 PF00704.28 KNZ72755.1 - 2.2e-57 195.2 0.1 2.8e-57 194.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-C2H2 PF00096.26 KNZ72756.1 - 4.7e-11 42.5 14.7 7.6e-05 22.9 1.7 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ72756.1 - 2.5e-08 34.1 12.2 0.00085 20.0 0.9 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ72756.1 - 4e-05 23.8 12.0 0.00024 21.4 0.6 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KNZ72756.1 - 0.0017 18.6 2.8 0.21 12.0 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ72756.1 - 0.02 15.3 6.4 8.7 6.9 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KNZ72756.1 - 0.062 13.6 4.4 0.66 10.3 2.8 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KNZ72756.1 - 1.2 9.2 8.5 0.89 9.6 0.7 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_carr PF00153.27 KNZ72757.1 - 1.5e-62 207.6 3.5 3e-21 75.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3844 PF12955.7 KNZ72758.1 - 1.4e-30 105.5 4.3 2.2e-30 104.9 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 KNZ72758.1 - 4.8 7.6 9.8 9.5 6.7 9.8 1.5 1 0 0 1 1 1 0 EGF-like domain Gti1_Pac2 PF09729.9 KNZ72759.1 - 2.4e-28 99.5 1.3 2.2e-24 86.6 0.0 2.4 2 1 1 3 3 3 2 Gti1/Pac2 family Glutaredoxin PF00462.24 KNZ72760.1 - 0.034 14.4 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin O-FucT PF10250.9 KNZ72761.1 - 3.9e-13 49.8 0.0 5.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Esterase_phd PF10503.9 KNZ72762.1 - 8.6e-25 87.5 1.0 1.4e-24 86.9 1.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KNZ72762.1 - 4e-13 49.1 14.9 1.4e-12 47.3 14.9 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KNZ72762.1 - 5.1e-09 35.9 0.8 9.5e-09 35.0 0.8 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KNZ72762.1 - 0.07 12.8 1.2 0.18 11.4 1.2 1.8 1 1 0 1 1 1 0 Putative esterase Glutaredoxin PF00462.24 KNZ72763.1 - 5e-12 45.8 0.0 8.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KNZ72763.1 - 0.016 15.7 0.0 0.02 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 KNZ72763.1 - 0.045 14.2 0.0 0.073 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HAD_2 PF13419.6 KNZ72764.1 - 4.1e-17 62.8 0.0 5.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ72764.1 - 1.3e-11 45.3 0.0 4.2e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KNZ72764.1 - 0.031 14.4 0.0 6.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Bax1-I PF01027.20 KNZ72766.1 - 1.7e-44 152.1 23.3 2e-44 151.9 23.3 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 KNZ72766.1 - 0.0028 17.2 16.4 0.0074 15.9 16.4 1.7 1 1 0 1 1 1 1 Bax inhibitor 1 like DUF1761 PF08570.10 KNZ72766.1 - 7.9 6.8 15.5 0.6 10.4 4.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) CMAS PF02353.20 KNZ72767.1 - 6.4e-32 110.9 0.1 8.9e-32 110.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KNZ72767.1 - 4.2e-14 53.0 0.0 7.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ72767.1 - 5.3e-13 49.4 0.0 1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ72767.1 - 2.1e-10 40.6 0.0 4.7e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ72767.1 - 6.4e-10 39.7 0.0 1.2e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ72767.1 - 1.5e-08 34.6 0.0 3.2e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ72767.1 - 8.7e-07 28.6 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KNZ72767.1 - 0.00017 21.1 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltr_RsmB-F PF01189.17 KNZ72767.1 - 0.0003 20.5 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F tRNA_U5-meth_tr PF05958.11 KNZ72767.1 - 0.00031 19.8 0.0 0.00044 19.3 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 KNZ72767.1 - 0.00041 19.8 0.1 0.00067 19.1 0.1 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 KNZ72767.1 - 0.0049 16.6 0.0 0.0067 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KNZ72767.1 - 0.01 15.5 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW DOT1 PF08123.13 KNZ72767.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 KNZ72767.1 - 0.042 13.8 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 KNZ72767.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 KNZ72767.1 - 0.1 12.3 0.1 0.21 11.3 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF938) IBD PF10416.9 KNZ72767.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD RrnaAD PF00398.20 KNZ72767.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 KNZ72767.1 - 0.16 11.2 0.0 0.37 10.1 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain MDM31_MDM32 PF08118.11 KNZ72768.1 - 1.9e-214 713.2 0.0 2.3e-214 713.0 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Babuvirus_MP PF07234.11 KNZ72768.1 - 0.16 12.1 0.3 0.37 11.0 0.3 1.5 1 0 0 1 1 1 0 Movement and RNA silencing protein BAR PF03114.18 KNZ72771.1 - 1.1e-42 146.3 0.1 1.3e-42 146.1 0.1 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 KNZ72771.1 - 0.0058 16.2 0.4 0.021 14.4 0.1 1.8 2 0 0 2 2 2 1 Arfaptin-like domain SYF2 PF08231.12 KNZ72771.1 - 0.0094 16.4 0.7 0.015 15.7 0.7 1.4 1 0 0 1 1 1 1 SYF2 splicing factor LPD39 PF18858.1 KNZ72771.1 - 0.039 14.1 1.6 0.12 12.4 0.3 2.3 3 0 0 3 3 3 0 Large polyvalent protein associated domain 39 Casc1_N PF15927.5 KNZ72771.1 - 0.04 13.6 1.9 0.057 13.1 0.7 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus UvdE PF03851.14 KNZ72772.1 - 1.1e-83 280.7 0.0 1.5e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE UPF0767 PF15990.5 KNZ72772.1 - 7.3 6.8 5.6 12 6.2 0.6 3.1 3 0 0 3 3 3 0 UPF0767 family RabGAP-TBC PF00566.18 KNZ72774.1 - 4.9e-52 176.7 0.2 9.4e-52 175.8 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain APG6_N PF17675.1 KNZ72774.1 - 0.0083 16.7 6.8 0.0083 16.7 6.8 2.6 3 0 0 3 3 3 1 Apg6 coiled-coil region Phage_GP20 PF06810.11 KNZ72774.1 - 0.014 15.2 2.8 0.021 14.6 1.4 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 ZapB PF06005.12 KNZ72774.1 - 0.69 10.4 7.9 28 5.2 0.0 3.0 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KNZ72774.1 - 1 9.2 8.3 3 7.7 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator Endonuc-dimeris PF09124.10 KNZ72774.1 - 1.5 9.0 3.6 16 5.8 0.2 2.7 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Yippee-Mis18 PF03226.14 KNZ72775.1 - 9.3e-06 25.8 0.1 1.2e-05 25.5 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Amidohydro_1 PF01979.20 KNZ72776.1 - 1.6e-30 106.6 0.0 3e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KNZ72776.1 - 6.2e-13 49.0 0.1 1e-05 25.3 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family zf-RING_2 PF13639.6 KNZ72777.1 - 2.5e-12 46.9 5.2 5.1e-12 45.9 5.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KNZ72777.1 - 1.6e-07 30.9 1.5 1.6e-07 30.9 1.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KNZ72777.1 - 1.4e-06 28.0 6.0 1.5e-06 27.9 4.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KNZ72777.1 - 2.5e-05 24.0 2.7 5e-05 23.0 2.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KNZ72777.1 - 3e-05 24.0 0.6 6.9e-05 22.8 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 KNZ72777.1 - 4.7e-05 23.2 2.7 9.5e-05 22.2 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KNZ72777.1 - 6.6e-05 23.1 5.2 0.00028 21.1 5.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KNZ72777.1 - 0.00016 21.5 1.6 0.00033 20.6 1.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KNZ72777.1 - 0.0033 17.2 0.9 0.0072 16.2 0.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ72777.1 - 0.0099 15.9 6.8 0.045 13.8 1.0 2.8 3 0 0 3 3 2 1 RING-type zinc-finger RINGv PF12906.7 KNZ72777.1 - 0.012 15.8 2.5 0.023 14.8 2.5 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 KNZ72777.1 - 0.014 15.5 1.6 0.044 14.0 1.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KNZ72777.1 - 0.015 15.1 5.9 0.18 11.7 6.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 KNZ72777.1 - 0.16 11.9 2.5 2.7 8.0 0.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KNZ72777.1 - 0.53 10.2 2.6 1.3 9.0 2.6 1.7 1 0 0 1 1 1 0 PHD-finger Josephin PF02099.17 KNZ72778.1 - 1.6e-45 155.1 0.1 1.6e-45 155.1 0.1 2.1 2 0 0 2 2 2 1 Josephin UIM PF02809.20 KNZ72778.1 - 0.66 10.0 18.0 1.3 9.1 1.2 4.0 3 0 0 3 3 3 0 Ubiquitin interaction motif RMI1_N PF08585.12 KNZ72778.1 - 1.6 8.5 4.5 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 RecQ mediated genome instability protein Bac_rhamnosid6H PF17389.2 KNZ72779.1 - 1.6e-12 47.4 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KNZ72779.1 - 1.6e-06 27.8 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 KNZ72779.1 - 0.0015 17.4 0.1 0.0022 16.9 0.1 1.1 1 0 0 1 1 1 1 Trehalase Autoind_bind PF03472.15 KNZ72779.1 - 0.022 14.3 0.3 0.058 12.9 0.3 1.7 1 0 0 1 1 1 0 Autoinducer binding domain ATG27 PF09451.10 KNZ72780.1 - 3e-58 197.8 0.0 4e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KNZ72780.1 - 0.00017 20.8 0.0 0.00032 19.9 0.0 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Cauli_VI PF01693.16 KNZ72781.1 - 3.9e-13 49.5 0.0 6.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin DASH_Duo1 PF08651.10 KNZ72782.1 - 8e-21 73.6 0.5 1.3e-20 72.9 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 LMBR1 PF04791.16 KNZ72782.1 - 8.4 5.2 5.1 11 4.8 5.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DEAD PF00270.29 KNZ72783.1 - 2.6e-41 141.3 0.0 6.3e-41 140.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ72783.1 - 6.2e-24 84.5 0.1 3.4e-23 82.1 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KNZ72783.1 - 1.8e-20 72.9 2.3 6.1e-20 71.2 2.3 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain EMP70 PF02990.16 KNZ72784.1 - 7.6e-199 661.7 2.6 9.3e-199 661.4 2.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TGT PF01702.18 KNZ72785.1 - 1.1e-124 416.2 0.0 1.4e-124 415.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Glyco_hydro_70 PF02324.16 KNZ72785.1 - 0.3 9.2 0.0 0.42 8.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 tRNA-synt_1b PF00579.25 KNZ72786.1 - 2.2e-67 227.5 0.0 2.9e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 KNZ72786.1 - 0.0019 17.9 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 S4 domain Abhydrolase_1 PF00561.20 KNZ72787.1 - 4e-11 43.1 0.0 1.3e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ72787.1 - 0.0053 17.4 0.1 0.007 17.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosom_S12_S23 PF00164.25 KNZ72788.1 - 3.2e-47 158.9 0.8 4.4e-47 158.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Transglut_core PF01841.19 KNZ72789.1 - 1.6e-10 41.4 0.0 2.4e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KNZ72789.1 - 0.21 11.1 0.0 2 7.9 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain CTP_transf_1 PF01148.20 KNZ72790.1 - 1.3e-71 241.5 21.2 1.9e-71 240.9 21.2 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Topoisom_I PF01028.20 KNZ72791.1 - 2.9e-98 327.8 8.0 2.9e-98 327.8 8.0 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KNZ72791.1 - 1.2e-96 322.4 0.7 1.2e-96 322.4 0.7 3.2 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KNZ72791.1 - 1.5e-35 121.0 0.2 5.5e-35 119.1 0.2 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain NDUF_B12 PF08122.12 KNZ72792.1 - 1.5e-20 73.0 0.2 1.8e-20 72.7 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Chromate_transp PF02417.15 KNZ72792.1 - 0.0097 16.1 0.0 0.011 15.9 0.0 1.0 1 0 0 1 1 1 1 Chromate transporter MipZ PF09140.11 KNZ72792.1 - 0.031 13.6 0.0 0.032 13.5 0.0 1.0 1 0 0 1 1 1 0 ATPase MipZ Cation_ATPase_C PF00689.21 KNZ72792.1 - 0.041 13.6 0.0 0.041 13.6 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus HAD_2 PF13419.6 KNZ72793.1 - 1.8e-05 24.9 0.0 4.8e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ72793.1 - 0.03 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF2608 PF11019.8 KNZ72793.1 - 0.042 13.3 0.0 0.8 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) PALP PF00291.25 KNZ72794.1 - 6e-78 262.2 0.0 7.8e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KNZ72794.1 - 5e-39 132.0 0.0 2.2e-21 75.4 0.0 2.6 3 0 0 3 3 3 2 C-terminal regulatory domain of Threonine dehydratase PHD PF00628.29 KNZ72795.1 - 3.6e-11 42.8 7.9 6e-11 42.1 7.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 KNZ72795.1 - 0.039 14.0 1.8 0.081 13.0 1.8 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger DUF4890 PF16231.5 KNZ72795.1 - 0.084 13.4 0.2 0.084 13.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4890) PHD_2 PF13831.6 KNZ72795.1 - 0.12 12.0 3.9 0.21 11.2 3.9 1.4 1 0 0 1 1 1 0 PHD-finger Vps8 PF12816.7 KNZ72796.1 - 3.8e-67 225.6 0.1 1.6e-65 220.3 0.0 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KNZ72796.1 - 0.00035 20.5 0.0 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS PQQ_3 PF13570.6 KNZ72796.1 - 0.0063 17.0 0.3 1.8 9.2 0.0 2.8 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KNZ72796.1 - 0.047 14.0 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ72796.1 - 0.3 12.0 3.0 0.45 11.5 0.0 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF3510 PF12022.8 KNZ72797.1 - 5.4e-33 114.1 0.0 1.7e-32 112.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 KNZ72797.1 - 7.7e-25 87.5 6.5 2.3e-24 86.0 6.5 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.13 KNZ72797.1 - 0.02 13.5 1.4 0.04 12.5 1.4 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Vps51 PF08700.11 KNZ72797.1 - 0.031 14.4 2.0 0.062 13.4 0.6 2.3 2 1 0 2 2 2 0 Vps51/Vps67 Spc7 PF08317.11 KNZ72797.1 - 0.095 11.6 5.2 0.19 10.6 5.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2407 PF10302.9 KNZ72797.1 - 0.13 12.8 0.6 0.46 11.1 0.2 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DFF-C PF09033.10 KNZ72797.1 - 0.18 11.7 4.9 0.7 9.8 4.9 2.0 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain YabA PF06156.13 KNZ72797.1 - 1.7 9.3 3.3 9.4 6.9 0.2 3.1 3 0 0 3 3 3 0 Initiation control protein YabA DUF1168 PF06658.12 KNZ72798.1 - 1.1e-38 132.2 13.1 1.4e-38 131.8 13.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) PNMA PF14893.6 KNZ72798.1 - 0.0048 16.4 0.7 0.0064 15.9 0.7 1.3 1 0 0 1 1 1 1 PNMA CENP-Q PF13094.6 KNZ72798.1 - 0.65 10.2 12.0 0.54 10.5 9.8 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CMS1 PF14617.6 KNZ72798.1 - 1.6 8.0 8.9 2.4 7.4 8.9 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3987 PF13148.6 KNZ72798.1 - 2.7 6.9 9.6 4.6 6.2 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Coilin_N PF15862.5 KNZ72798.1 - 9.2 6.1 9.5 14 5.5 9.5 1.3 1 0 0 1 1 1 0 Coilin N-terminus MCM PF00493.23 KNZ72799.1 - 1.4e-98 328.5 0.0 2.1e-98 327.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNZ72799.1 - 1.1e-36 125.5 0.8 2.1e-36 124.5 0.8 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KNZ72799.1 - 6.9e-29 100.1 1.4 1.4e-28 99.2 1.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KNZ72799.1 - 1.1e-17 64.5 0.0 3.8e-17 62.8 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 KNZ72799.1 - 1.7e-08 34.6 0.0 4.6e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KNZ72799.1 - 1.2e-07 31.3 0.0 8e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KNZ72799.1 - 3.7e-05 23.6 0.0 0.0015 18.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNZ72799.1 - 0.0011 18.7 0.1 1 9.0 0.0 3.1 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_16 PF13191.6 KNZ72799.1 - 0.0039 17.6 0.1 0.018 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KNZ72799.1 - 0.13 12.7 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ank_4 PF13637.6 KNZ72800.1 - 5.8e-12 45.9 0.2 9e-06 26.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KNZ72800.1 - 4.2e-05 23.8 0.1 0.00012 22.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 KNZ72800.1 - 6.4e-05 23.5 0.1 0.00014 22.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ72800.1 - 0.00091 19.5 0.1 0.002 18.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ72800.1 - 0.0019 18.5 0.2 0.017 15.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Sybindin PF04099.12 KNZ72801.1 - 1.4e-16 60.7 0.0 2.1e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family SNF2_N PF00176.23 KNZ72802.1 - 5.7e-59 199.6 0.1 1.3e-58 198.5 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ72802.1 - 3.2e-19 69.3 0.0 1.8e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ72802.1 - 6.5e-11 42.5 0.0 5e-09 36.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNZ72802.1 - 1.6e-05 24.2 0.2 3.3e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 KNZ72802.1 - 4.9e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Mito_carr PF00153.27 KNZ72803.1 - 1.5e-13 50.5 0.0 3.8e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF1365 PF07103.11 KNZ72804.1 - 2.3e-54 184.6 0.0 3.4e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) zf-CCCH PF00642.24 KNZ72806.1 - 2.1e-05 24.3 2.9 5.1e-05 23.1 2.9 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNZ72806.1 - 0.0054 16.8 2.4 0.015 15.3 2.4 1.8 1 1 0 1 1 1 1 Zinc finger domain RRM_1 PF00076.22 KNZ72806.1 - 0.062 13.1 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg14 PF08660.11 KNZ72807.1 - 1e-54 185.1 0.0 1.4e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TPR_1 PF00515.28 KNZ72808.1 - 1.4e-24 84.9 8.9 0.00011 21.9 1.7 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72808.1 - 7.2e-23 78.9 7.5 3.1e-05 23.8 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat ANAPC8 PF04049.13 KNZ72808.1 - 3.9e-18 65.8 0.0 3.8e-17 62.6 0.0 2.6 3 1 0 3 3 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.17 KNZ72808.1 - 1.5e-16 59.1 18.0 0.015 15.3 0.1 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ72808.1 - 4e-16 58.3 15.4 0.0063 17.2 0.1 8.4 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ72808.1 - 8.1e-11 41.4 3.6 1.1e-06 28.2 0.5 4.8 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.6 KNZ72808.1 - 1.5e-09 38.0 19.2 0.00013 22.2 0.7 5.6 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72808.1 - 1.7e-08 34.3 1.6 0.47 11.0 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ72808.1 - 2e-08 34.7 14.4 2.2e-06 28.2 0.2 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72808.1 - 5.3e-08 32.3 14.4 0.5 10.5 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ72808.1 - 3.1e-06 27.3 13.0 0.077 13.2 0.0 4.3 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KNZ72808.1 - 1.1e-05 25.8 12.2 0.07 13.6 0.1 6.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72808.1 - 5.7e-05 23.2 11.6 0.00064 19.8 1.2 4.4 3 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ72808.1 - 0.00026 21.4 6.0 14 6.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ72808.1 - 0.00035 20.3 5.9 0.075 12.9 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ72808.1 - 0.0039 16.5 2.7 0.0039 16.5 2.7 2.6 2 1 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 KNZ72808.1 - 0.0078 15.3 0.0 0.085 11.8 0.0 2.3 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.7 KNZ72808.1 - 0.26 11.3 2.2 1.9 8.5 0.1 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) GLTSCR1 PF15249.6 KNZ72809.1 - 1.3e-25 89.8 0.4 2e-25 89.2 0.4 1.3 1 0 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein Voltage_CLC PF00654.20 KNZ72810.1 - 2.1e-88 297.0 20.2 2.1e-88 297.0 20.2 2.1 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KNZ72810.1 - 0.0029 18.0 0.1 0.51 10.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain LSM PF01423.22 KNZ72811.1 - 5e-14 51.7 0.2 6.5e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KNZ72811.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 KNZ72811.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain E3_binding PF02817.17 KNZ72811.1 - 0.029 14.7 0.1 0.062 13.7 0.1 1.6 1 0 0 1 1 1 0 e3 binding domain DUF1674 PF07896.12 KNZ72812.1 - 4.8e-16 59.0 3.6 4.8e-16 59.0 3.6 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.18 KNZ72813.1 - 6.9e-21 74.5 0.7 1.1e-20 73.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ72813.1 - 2.5e-09 37.1 13.3 4.9e-09 36.2 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KNZ72813.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Ribosomal_S8e PF01201.22 KNZ72814.1 - 4e-47 159.8 0.7 1.3e-46 158.2 0.7 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e Yip1 PF04893.17 KNZ72815.1 - 1.1e-05 25.2 11.7 1.7e-05 24.6 11.7 1.3 1 0 0 1 1 1 1 Yip1 domain CX9C PF16860.5 KNZ72817.1 - 0.00064 19.7 0.4 1.2 9.2 0.1 2.2 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 KNZ72817.1 - 0.0065 16.7 0.7 0.043 14.1 0.7 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 KNZ72817.1 - 0.042 13.9 1.3 0.096 12.7 0.5 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1746 PF08508.10 KNZ72818.1 - 9.8e-10 38.8 0.4 2.4e-09 37.5 0.4 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Tetraspanin PF00335.20 KNZ72819.1 - 7.1e-06 25.9 12.1 1.6e-05 24.7 12.1 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF2970 PF11174.8 KNZ72819.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) COX2_TM PF02790.15 KNZ72819.1 - 1.8 8.8 7.9 1.4 9.1 0.3 3.0 1 1 3 4 4 4 0 Cytochrome C oxidase subunit II, transmembrane domain Amidohydro_1 PF01979.20 KNZ72820.1 - 6.3e-14 52.0 0.0 8.9e-11 41.7 0.0 2.9 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.11 KNZ72820.1 - 1.5e-11 44.5 4.1 3.1e-07 30.2 0.0 3.4 4 0 0 4 4 4 2 Amidohydrolase family SARAF PF06682.12 KNZ72821.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis UME PF08064.13 KNZ72821.1 - 0.097 12.6 0.4 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 UME (NUC010) domain Caskin-tail PF16632.5 KNZ72821.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of Caskin Plavaka PF18759.1 KNZ72822.1 - 4.7e-11 42.5 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase Rad10 PF03834.14 KNZ72823.1 - 8.7e-45 151.4 0.2 1.5e-44 150.7 0.2 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 KNZ72823.1 - 4e-07 30.5 0.0 9.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KNZ72823.1 - 0.00091 19.3 0.0 0.0047 17.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 KNZ72823.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Amidohydro_3 PF07969.11 KNZ72824.1 - 1.6e-13 51.0 1.3 4e-08 33.2 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KNZ72824.1 - 2.4e-12 46.8 0.0 7.9e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family REPA_OB_2 PF16900.5 KNZ72824.1 - 0.064 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Replication protein A OB domain Abhydrolase_3 PF07859.13 KNZ72825.1 - 1.1e-24 87.5 0.0 1.6e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KNZ72825.1 - 6.8e-12 44.9 0.0 1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3128 PF11326.8 KNZ72826.1 - 1.7e-22 79.6 0.2 2.1e-22 79.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MCM PF00493.23 KNZ72827.1 - 3.3e-100 333.8 0.0 4.7e-100 333.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNZ72827.1 - 5.9e-35 119.9 0.0 1e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KNZ72827.1 - 3.2e-34 118.4 29.1 3.2e-34 118.4 29.1 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KNZ72827.1 - 4.6e-26 91.1 0.4 2.8e-25 88.5 0.7 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KNZ72827.1 - 9.3e-14 51.9 0.0 3.1e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KNZ72827.1 - 1.4e-07 31.1 0.0 3.8e-06 26.4 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KNZ72827.1 - 5.6e-06 26.4 0.0 1.4e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) SelR PF01641.18 KNZ72827.1 - 0.00086 19.4 0.2 0.4 10.8 0.1 2.4 2 0 0 2 2 2 2 SelR domain AAA_3 PF07726.11 KNZ72827.1 - 0.0012 18.7 0.1 0.013 15.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNZ72827.1 - 0.0024 17.6 0.1 0.02 14.6 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 KNZ72827.1 - 0.032 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Sec23_Sec24 PF04810.15 KNZ72827.1 - 0.24 11.5 0.4 0.45 10.6 0.4 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger CHCH PF06747.13 KNZ72828.1 - 8.2e-09 35.4 2.6 1.3e-08 34.7 2.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 KNZ72828.1 - 0.019 15.4 1.3 0.031 14.7 1.3 1.3 1 0 0 1 1 1 0 GCK domain LPD23 PF18838.1 KNZ72829.1 - 0.043 13.6 1.0 0.084 12.7 0.1 2.0 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 Pkinase PF00069.25 KNZ72830.1 - 3.6e-58 197.0 0.0 4.2e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72830.1 - 2.2e-16 59.9 0.0 3.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ72830.1 - 4.1e-06 26.9 0.0 0.022 14.7 0.2 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ72830.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Tai4 PF16695.5 KNZ72830.1 - 0.078 13.5 0.1 1.1 9.9 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system (T6SS), amidase immunity protein Sec7 PF01369.20 KNZ72831.1 - 4.4e-36 124.3 0.0 6.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 KNZ72831.1 - 0.0099 15.9 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Fe-ADH PF00465.19 KNZ72832.1 - 1.9e-61 207.9 0.0 2.3e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KNZ72832.1 - 3.6e-14 53.1 0.0 7.2e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Cation_efflux PF01545.21 KNZ72833.1 - 1e-45 156.0 2.0 1.4e-45 155.5 2.0 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KNZ72833.1 - 6.4e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Lyase_aromatic PF00221.19 KNZ72834.1 - 1.3e-146 489.0 4.2 1.6e-146 488.7 4.2 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Tcp11 PF05794.13 KNZ72835.1 - 2.5e-10 40.1 0.0 0.0015 17.7 0.0 2.9 2 1 0 2 2 2 2 T-complex protein 11 GDH_N PF12466.8 KNZ72835.1 - 0.14 12.4 0.0 3.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Cnd3 PF12719.7 KNZ72836.1 - 6.7e-71 238.9 8.6 1.8e-70 237.4 5.1 2.6 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KNZ72836.1 - 7.6e-07 28.9 4.6 0.056 13.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 KNZ72836.1 - 1.9e-06 28.1 0.3 0.0013 19.1 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KNZ72836.1 - 0.0077 16.7 2.2 0.72 10.4 0.0 4.4 4 0 0 4 4 4 1 HEAT-like repeat DUF5031 PF16434.5 KNZ72836.1 - 0.029 13.5 0.1 0.061 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) DUF1040 PF06288.13 KNZ72836.1 - 0.3 11.5 2.1 0.5 10.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1040) Pneumo_att_G PF05539.11 KNZ72836.1 - 4 6.9 7.3 7.1 6.1 7.3 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mg_trans_NIPA PF05653.14 KNZ72837.1 - 5.9e-14 51.9 12.4 9.8e-11 41.3 1.3 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA Ssl1 PF04056.14 KNZ72838.1 - 1.5e-69 233.7 0.0 2.5e-69 233.0 0.0 1.4 1 1 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KNZ72838.1 - 1.4e-11 44.9 0.0 2.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 KNZ72838.1 - 0.018 14.5 6.3 9 5.7 7.6 2.2 2 0 0 2 2 2 0 Transcription factor Tfb4 VWA PF00092.28 KNZ72838.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4428 PF14471.6 KNZ72838.1 - 0.38 10.7 2.6 1.3 9.0 2.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Hist_deacetyl PF00850.19 KNZ72839.1 - 3.1e-90 302.8 0.0 4.5e-90 302.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 KNZ72839.1 - 2.1e-36 125.4 0.0 3.1e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Form_Nir_trans PF01226.17 KNZ72840.1 - 2.1e-70 236.8 22.1 3e-68 229.7 22.1 2.0 1 1 0 1 1 1 1 Formate/nitrite transporter RRM_2 PF04059.12 KNZ72841.1 - 3.6e-33 113.6 0.9 6.5e-33 112.8 0.9 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KNZ72841.1 - 1.1e-05 25.1 0.8 0.018 14.8 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 KNZ72841.1 - 0.00096 19.3 0.1 0.0018 18.5 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 Ribosomal_S6 PF01250.17 KNZ72842.1 - 4.9e-20 71.6 0.0 7.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 MarR_2 PF12802.7 KNZ72842.1 - 0.057 13.3 0.4 0.095 12.6 0.1 1.5 2 0 0 2 2 2 0 MarR family Cpn60_TCP1 PF00118.24 KNZ72843.1 - 3.3e-161 537.2 0.9 4.9e-161 536.7 0.9 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Amidohydro_2 PF04909.14 KNZ72845.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase HAUS-augmin3 PF14932.6 KNZ72846.1 - 0.0012 18.5 6.9 0.0087 15.7 6.9 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 V_ATPase_I PF01496.19 KNZ72846.1 - 0.29 9.0 4.1 0.43 8.5 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KNZ72846.1 - 0.79 8.3 6.0 1.3 7.6 6.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 KNZ72846.1 - 1.5 8.1 6.9 2.4 7.4 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MIF4G PF02854.19 KNZ72847.1 - 3.4e-47 160.8 1.3 9.3e-30 103.9 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KNZ72847.1 - 1.2e-29 103.7 8.6 1.6e-29 103.4 3.1 3.0 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Tnp_P_element PF12017.8 KNZ72847.1 - 0.0094 15.4 0.2 0.11 11.9 0.2 2.4 2 0 0 2 2 2 1 Transposase protein SNase PF00565.17 KNZ72848.1 - 1.7e-58 195.7 0.0 4.6e-21 75.3 0.0 6.2 5 1 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.24 KNZ72848.1 - 2.4e-07 30.8 0.0 3.7e-05 23.7 0.0 2.5 1 1 0 1 1 1 1 Tudor domain Hydrolase PF00702.26 KNZ72849.1 - 7.9e-14 52.4 0.0 1.1e-13 52.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KNZ72849.1 - 1e-13 51.8 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ72849.1 - 6.9e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like SET PF00856.28 KNZ72850.1 - 6.6e-11 42.9 1.2 4.7e-10 40.1 0.1 2.7 2 1 0 2 2 2 1 SET domain AT_hook PF02178.19 KNZ72850.1 - 0.13 12.2 3.7 0.9 9.6 3.7 2.6 1 0 0 1 1 1 0 AT hook motif ubiquitin PF00240.23 KNZ72851.1 - 6.7e-170 551.2 26.1 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KNZ72851.1 - 3.3e-78 257.5 28.3 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KNZ72851.1 - 4.3e-28 97.6 13.6 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KNZ72851.1 - 1.9e-19 69.4 6.0 0.041 13.8 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KNZ72851.1 - 1.6e-17 63.6 4.7 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KNZ72851.1 - 3.3e-17 62.6 12.2 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 KNZ72851.1 - 6.6e-16 58.8 2.9 0.43 11.2 0.0 5.2 1 1 0 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KNZ72851.1 - 4.8e-12 46.0 0.8 1.9 8.3 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 KNZ72851.1 - 5.4e-09 35.7 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KNZ72851.1 - 1.4e-07 31.5 32.8 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 KNZ72851.1 - 2e-07 31.3 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 KNZ72851.1 - 2e-07 31.6 0.7 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF3861 PF12977.7 KNZ72851.1 - 5.1e-07 29.8 5.6 16 5.8 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) TmoB PF06234.12 KNZ72851.1 - 1.3e-06 28.4 0.1 40 4.4 0.0 5.7 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) ACT_5 PF13710.6 KNZ72851.1 - 2.6e-06 27.2 6.9 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 KNZ72851.1 - 6.4e-06 26.2 6.6 9.2 6.4 0.1 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KNZ72851.1 - 2.3e-05 24.0 0.1 27 4.1 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KNZ72851.1 - 0.0001 22.8 2.3 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 KNZ72851.1 - 0.00034 21.1 0.1 1.7e+02 2.9 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KNZ72851.1 - 0.00063 19.8 0.0 1.2e+02 2.9 0.0 5.2 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KNZ72851.1 - 0.015 15.4 8.6 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KNZ72851.1 - 0.11 12.3 13.6 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 KNZ72851.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif YcgR_2 PF12945.7 KNZ72851.1 - 0.7 10.1 8.1 61 3.9 0.1 4.9 5 0 0 5 5 5 0 Flagellar protein YcgR Phage_sheath_1N PF17481.2 KNZ72851.1 - 0.93 10.0 13.3 1.2e+02 3.2 0.1 4.9 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain PI3K_p85B PF02192.16 KNZ72851.1 - 6.2 6.6 13.2 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Ribosomal_S4e PF00900.20 KNZ72851.1 - 7.1 6.6 12.3 1.4e+02 2.5 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e Cnl2_NKP2 PF09447.10 KNZ72851.1 - 8.3 6.6 14.2 1.3e+02 2.8 0.1 5.2 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Nop25 PF09805.9 KNZ72852.1 - 1.8e-22 80.3 20.2 1.8e-22 80.3 20.2 2.3 2 0 0 2 2 2 2 Nucleolar protein 12 (25kDa) DUF4741 PF15897.5 KNZ72852.1 - 0.55 10.0 4.0 7 6.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4741) V-SNARE_C PF12352.8 KNZ72853.1 - 4.3e-16 59.0 0.4 4.3e-16 59.0 0.4 2.5 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KNZ72853.1 - 0.012 15.5 1.9 0.085 12.8 0.0 2.6 2 1 1 3 3 3 0 Sec20 HALZ PF02183.18 KNZ72853.1 - 0.038 14.2 0.0 0.93 9.8 0.0 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper MCU PF04678.13 KNZ72853.1 - 0.057 13.5 0.6 0.096 12.8 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Plasmid_RAQPRD PF09686.10 KNZ72853.1 - 0.26 11.5 5.0 0.49 10.6 1.6 2.7 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Lactamase_B PF00753.27 KNZ72854.1 - 8.1e-05 22.7 0.8 0.00015 21.8 0.8 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KNZ72854.1 - 0.0006 19.4 0.1 0.00096 18.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PIRT PF15099.6 KNZ72854.1 - 0.18 11.4 2.3 0.24 11.0 0.5 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family E1-E2_ATPase PF00122.20 KNZ72855.1 - 1.4e-30 106.2 0.0 4.8e-30 104.4 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 KNZ72855.1 - 1.5e-22 80.0 0.1 3.6e-22 78.8 0.1 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 KNZ72855.1 - 1e-16 61.8 0.0 2.8e-07 31.0 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KNZ72855.1 - 3.4e-08 33.4 6.8 3.4e-08 33.4 6.8 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KNZ72855.1 - 2.8e-05 24.1 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNZ72855.1 - 0.0039 16.8 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNZ72855.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short_C2 PF13561.6 KNZ72856.1 - 2.5e-44 151.6 0.1 4.1e-44 150.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ72856.1 - 7e-26 90.9 0.1 2.4e-25 89.1 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ72856.1 - 3.6e-06 27.0 0.0 5.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DinI PF06183.13 KNZ72856.1 - 0.014 15.7 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 DinI-like family Methyltransf_25 PF13649.6 KNZ72856.1 - 0.043 14.5 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SbcD_C PF12320.8 KNZ72856.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain p450 PF00067.22 KNZ72857.1 - 5.5e-53 180.3 0.2 6.5e-53 180.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Troponin PF00992.20 KNZ72857.1 - 0.035 14.4 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 Troponin FKBP_C PF00254.28 KNZ72858.1 - 6.5e-32 109.7 0.1 1.3e-31 108.7 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 KNZ72858.1 - 2.2e-20 73.1 0.1 2.2e-20 73.1 0.1 2.1 2 1 0 2 2 2 1 Nucleoplasmin-like domain YL1 PF05764.13 KNZ72858.1 - 0.045 13.9 18.8 0.066 13.3 18.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein RNA_pol_Rpc4 PF05132.14 KNZ72858.1 - 0.27 11.7 7.4 0.56 10.6 7.4 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Borrelia_P83 PF05262.11 KNZ72858.1 - 1.4 7.4 17.3 1.9 6.9 17.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 KNZ72858.1 - 1.8 7.2 7.6 2.5 6.8 7.6 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 KNZ72858.1 - 6.4 4.9 17.8 8.7 4.5 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein ARPC4 PF05856.12 KNZ72859.1 - 4.1e-75 251.0 3.6 4.6e-75 250.8 3.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Ten1_2 PF15490.6 KNZ72860.1 - 0.0026 17.4 0.0 0.0029 17.3 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ribosomal_S7 PF00177.21 KNZ72863.1 - 4.7e-37 126.9 1.3 5.8e-37 126.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Chorismate_bind PF00425.18 KNZ72864.1 - 0.034 13.7 0.2 0.055 13.0 0.2 1.3 1 0 0 1 1 1 0 chorismate binding enzyme TPR_7 PF13176.6 KNZ72864.1 - 0.097 12.8 0.2 19 5.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat APG6_N PF17675.1 KNZ72864.1 - 0.34 11.4 10.2 0.7 10.4 10.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1690 PF07956.11 KNZ72864.1 - 0.36 11.3 6.0 0.74 10.2 5.6 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2508 PF10704.9 KNZ72864.1 - 1.2 9.4 6.0 2.9 8.1 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) FUSC PF04632.12 KNZ72864.1 - 1.8 7.0 3.5 2.3 6.6 3.5 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-H PF05837.12 KNZ72864.1 - 2.9 8.4 7.3 1.7 9.1 5.3 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SNF2_N PF00176.23 KNZ72866.1 - 4.8e-61 206.4 0.1 7.1e-61 205.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KNZ72866.1 - 1.3e-16 60.2 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.18 KNZ72866.1 - 2.4e-10 41.1 0.0 6e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.31 KNZ72866.1 - 4.7e-10 39.8 0.0 1.2e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KNZ72866.1 - 7.8e-09 35.2 6.3 2.2e-08 33.8 6.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ72866.1 - 4.5e-08 32.8 6.4 1.1e-07 31.6 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ72866.1 - 5.7e-08 32.5 2.6 1.1e-07 31.5 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ72866.1 - 1.2e-06 28.7 6.0 2.5e-06 27.7 6.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KNZ72866.1 - 4e-06 26.7 3.8 7.6e-06 25.8 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ72866.1 - 9.2e-06 25.6 8.3 2.1e-05 24.4 8.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 KNZ72866.1 - 2.1e-05 24.6 0.0 5.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KNZ72866.1 - 6.8e-05 22.7 4.5 0.00022 21.0 4.8 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KNZ72866.1 - 0.00023 21.4 2.0 0.00065 19.9 2.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KNZ72866.1 - 0.00027 21.0 7.4 0.00074 19.6 7.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DEAD PF00270.29 KNZ72866.1 - 0.013 15.3 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase zf-RING_11 PF17123.5 KNZ72866.1 - 0.54 10.0 6.4 1.2 9.0 6.4 1.6 1 0 0 1 1 1 0 RING-like zinc finger Acetyltransf_3 PF13302.7 KNZ72867.1 - 1.6e-18 67.7 0.0 2.1e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ72867.1 - 2.8e-05 24.3 0.0 3.9e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family F-box-like PF12937.7 KNZ72868.1 - 1e-08 34.9 2.7 2.9e-08 33.5 2.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ72868.1 - 0.00044 20.1 0.9 0.0012 18.6 0.9 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 KNZ72869.1 - 4.9e-26 90.5 13.8 0.00012 22.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ72869.1 - 1.6e-07 31.5 0.1 0.0057 16.9 0.0 4.4 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ72869.1 - 0.00011 21.6 0.1 0.0022 17.4 0.1 2.7 2 1 1 3 3 3 1 WD40-like domain PQQ PF01011.21 KNZ72869.1 - 0.00018 21.3 0.0 2.7 8.1 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.6 KNZ72869.1 - 0.00055 19.6 1.0 0.03 13.9 1.1 2.3 1 1 1 2 2 2 2 PQQ-like domain DUF5046 PF16465.5 KNZ72869.1 - 0.0058 16.1 0.4 0.14 11.5 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) Me-amine-dh_H PF06433.11 KNZ72869.1 - 0.11 11.4 0.1 0.7 8.7 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Marek_SORF3 PF07153.11 KNZ72869.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Ge1_WD40 PF16529.5 KNZ72869.1 - 0.18 10.7 0.0 1.7 7.5 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LSM PF01423.22 KNZ72870.1 - 1.3e-15 56.8 0.3 2.4e-15 56.0 0.2 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.6 KNZ72870.1 - 0.067 13.3 0.0 0.088 13.0 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Ribosomal_S8e PF01201.22 KNZ72871.1 - 2.7e-56 189.5 0.5 4.1e-56 188.9 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e UDPGP PF01704.18 KNZ72872.1 - 8.8e-161 535.1 0.0 1e-160 534.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase UDPGP PF01704.18 KNZ72873.1 - 5.1e-198 657.8 1.0 5.9e-198 657.6 1.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Thioredoxin_15 PF18403.1 KNZ72873.1 - 0.011 15.7 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Metallophos PF00149.28 KNZ72874.1 - 7.1e-16 59.3 0.6 9.8e-16 58.9 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CPSase_sm_chain PF00988.22 KNZ72875.1 - 1.5e-44 150.9 0.2 3.6e-44 149.7 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KNZ72875.1 - 1.6e-35 122.6 0.0 3.4e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KNZ72875.1 - 6.9e-07 29.2 0.1 9.6e-06 25.5 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KNZ72875.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family VP40 PF07447.12 KNZ72875.1 - 0.06 12.5 1.6 1.2 8.2 0.1 2.4 2 0 0 2 2 2 0 Matrix protein VP40 Usher_TcfC PF17271.2 KNZ72875.1 - 0.1 11.4 2.0 0.18 10.6 2.0 1.3 1 0 0 1 1 1 0 TcfC Usher-like barrel domain BSD PF03909.17 KNZ72876.1 - 6.8e-10 38.8 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 BSD domain BPL_N PF09825.9 KNZ72876.1 - 0.017 14.2 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF5018 PF16410.5 KNZ72876.1 - 0.088 11.5 0.3 0.14 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) Metallophos PF00149.28 KNZ72877.1 - 8e-07 29.8 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Scs3p PF10261.9 KNZ72878.1 - 3.1e-40 138.2 8.1 1.2e-33 116.7 0.4 2.2 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 KNZ72878.1 - 0.0059 16.4 3.4 0.0059 16.4 3.4 2.5 2 1 0 2 2 2 1 PAP2 superfamily DUF2085 PF09858.9 KNZ72878.1 - 4.9 7.7 8.4 4.2 7.9 0.6 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) ALAD PF00490.21 KNZ72879.1 - 1.2e-117 392.6 0.0 1.4e-117 392.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pkinase PF00069.25 KNZ72880.1 - 8.8e-47 159.7 0.0 1.8e-46 158.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72880.1 - 2.8e-31 108.8 0.0 7.2e-31 107.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ72880.1 - 0.052 13.5 0.0 0.16 11.9 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Homeodomain PF00046.29 KNZ72881.1 - 1.5e-18 66.4 0.6 2.8e-18 65.5 0.6 1.5 1 0 0 1 1 1 1 Homeodomain Aldo_ket_red PF00248.21 KNZ72882.1 - 3.2e-46 157.9 0.0 2.7e-34 118.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family bZIP_2 PF07716.15 KNZ72883.1 - 0.069 13.2 1.6 0.17 12.0 0.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 KNZ72883.1 - 0.12 12.5 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 bZIP transcription factor BAG PF02179.16 KNZ72884.1 - 4.6e-18 65.4 0.2 6.4e-18 65.0 0.2 1.1 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KNZ72884.1 - 6.6e-07 29.0 0.0 9.6e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family TSKS PF15358.6 KNZ72884.1 - 0.023 13.1 0.0 0.024 13.0 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Pkinase PF00069.25 KNZ72885.1 - 3.8e-54 183.8 0.0 5.2e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72885.1 - 6.7e-36 123.9 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ72885.1 - 3.8e-06 26.4 0.0 6.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ72885.1 - 0.00069 19.6 0.3 0.21 11.5 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ72885.1 - 0.019 13.8 1.0 0.031 13.1 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 KNZ72885.1 - 0.034 13.1 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain tRNA-synt_1 PF00133.22 KNZ72886.1 - 7.2e-221 734.6 0.0 1.3e-220 733.7 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KNZ72886.1 - 1.2e-26 93.5 0.1 2.2e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KNZ72886.1 - 1.2e-13 50.6 0.0 0.00031 19.6 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KNZ72886.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zf-C2H2_jaz PF12171.8 KNZ72887.1 - 7.4e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ72887.1 - 1.9e-05 24.9 0.1 3.2e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KNZ72887.1 - 0.00026 21.0 1.7 0.00026 21.0 1.7 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KNZ72887.1 - 0.001 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 DBF zinc finger Orbi_VP6 PF01516.16 KNZ72887.1 - 0.034 13.7 0.6 0.034 13.7 0.6 1.8 2 0 0 2 2 2 0 Orbivirus helicase VP6 zf-C2H2_4 PF13894.6 KNZ72887.1 - 0.11 13.4 0.1 0.2 12.6 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger EXS PF03124.14 KNZ72888.1 - 1.1e-90 304.3 22.0 1.3e-90 304.1 22.0 1.0 1 0 0 1 1 1 1 EXS family 2-Hacid_dh_C PF02826.19 KNZ72889.1 - 6.8e-45 152.6 0.0 1e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNZ72889.1 - 4.1e-16 58.9 0.0 5.5e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNZ72889.1 - 1.7e-06 28.3 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 KNZ72889.1 - 0.052 14.0 0.1 16 6.0 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 KNZ72889.1 - 0.11 12.6 0.0 0.94 9.5 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Bromodomain PF00439.25 KNZ72890.1 - 1e-24 86.4 0.2 1.9e-24 85.6 0.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KNZ72890.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ72890.1 - 3e-05 24.0 0.0 5.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ72890.1 - 9.3e-05 22.8 0.1 0.00017 21.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cwf_Cwc_15 PF04889.12 KNZ72890.1 - 0.0069 16.1 1.0 0.013 15.2 1.0 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 KNZ72890.1 - 3.3 6.2 6.7 4.9 5.6 6.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 KNZ72890.1 - 8.9 6.8 8.8 1.3 9.5 4.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pro_isomerase PF00160.21 KNZ72891.1 - 3.8e-48 163.7 0.2 4.8e-48 163.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD p450 PF00067.22 KNZ72892.1 - 1e-52 179.5 0.0 1.5e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DEAD PF00270.29 KNZ72893.1 - 1.6e-39 135.5 0.0 2.8e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KNZ72893.1 - 3.1e-17 62.5 0.6 5.5e-17 61.8 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KNZ72893.1 - 3.9e-17 62.6 0.0 2.5e-16 60.0 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ72893.1 - 0.00092 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MOZ_SAS PF01853.18 KNZ72894.1 - 2.3e-79 265.2 0.2 3.2e-79 264.8 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KNZ72894.1 - 1.9e-21 75.4 0.7 4.4e-21 74.2 0.7 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KNZ72894.1 - 6.4e-17 61.2 0.0 1.3e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KNZ72894.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_Mga PF08280.11 KNZ72894.1 - 0.005 16.8 0.3 0.011 15.7 0.3 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_1 PF00583.25 KNZ72894.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ORC6 PF05460.13 KNZ72894.1 - 0.086 12.1 0.5 0.18 11.1 0.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LAG1-DNAbind PF09271.11 KNZ72896.1 - 2.6e-50 171.0 0.0 4.6e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.10 KNZ72896.1 - 8.6e-20 71.5 0.0 3.1e-18 66.5 0.0 2.6 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain PHC2_SAM_assoc PF16616.5 KNZ72897.1 - 1.6 9.5 6.8 0.13 13.0 0.8 2.3 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 PAC4 PF16093.5 KNZ72898.1 - 5e-23 81.1 0.1 8e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Pkinase PF00069.25 KNZ72899.1 - 4.4e-51 173.8 0.1 7.7e-51 173.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72899.1 - 4.6e-23 81.8 0.1 7.8e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ72899.1 - 0.00028 20.9 0.1 0.00028 20.9 0.1 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ72899.1 - 0.00065 19.4 1.0 0.0015 18.2 1.0 1.6 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KNZ72899.1 - 0.18 11.4 4.3 0.11 12.0 0.5 2.5 3 0 0 3 3 3 0 Choline/ethanolamine kinase Put_Phosphatase PF06888.12 KNZ72900.1 - 9.6e-42 143.0 1.2 1.6e-39 135.7 0.1 2.4 2 1 0 2 2 2 1 Putative Phosphatase BSD PF03909.17 KNZ72901.1 - 1.2e-14 54.0 0.6 2.6e-12 46.6 0.0 2.7 3 0 0 3 3 3 2 BSD domain HTH_Tnp_ISL3 PF13542.6 KNZ72901.1 - 0.045 13.2 0.1 0.34 10.3 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 PH_TFIIH PF08567.11 KNZ72901.1 - 0.072 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain CASP_C PF08172.12 KNZ72902.1 - 3.4e-74 249.4 0.0 3.4e-74 249.4 0.0 3.9 2 2 1 4 4 4 1 CASP C terminal CtIP_N PF10482.9 KNZ72902.1 - 0.018 15.1 2.2 0.018 15.1 2.2 5.3 5 0 0 5 5 5 0 Tumour-suppressor protein CtIP N-terminal domain PAC2 PF09754.9 KNZ72902.1 - 0.1 12.6 0.5 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 PAC2 family DUF4407 PF14362.6 KNZ72902.1 - 0.28 10.5 38.9 0.6 9.4 17.1 4.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 KNZ72902.1 - 5.2 7.1 36.6 1.1 9.4 0.1 5.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Ribosomal_S9 PF00380.19 KNZ72903.1 - 2e-41 141.3 0.1 4.4e-41 140.2 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 BRE1 PF08647.11 KNZ72904.1 - 4.9e-22 77.8 12.4 4.9e-22 77.8 12.4 7.2 4 3 3 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 KNZ72904.1 - 2.7e-07 30.3 9.6 5.6e-07 29.3 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ72904.1 - 1.1e-06 28.4 9.2 2.3e-06 27.3 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ72904.1 - 1.5e-06 28.0 6.6 3.5e-06 26.8 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ72904.1 - 4.5e-06 26.5 9.2 1.2e-05 25.2 9.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ72904.1 - 1.9e-05 24.6 6.6 3.8e-05 23.6 6.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KNZ72904.1 - 0.0001 22.6 8.5 0.0002 21.6 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KNZ72904.1 - 0.003 17.4 6.2 0.0073 16.1 6.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KNZ72904.1 - 0.0095 16.2 4.7 0.026 14.8 4.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KNZ72904.1 - 0.021 14.7 3.9 0.044 13.7 3.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein CALCOCO1 PF07888.11 KNZ72904.1 - 0.044 12.7 60.6 0.031 13.2 21.7 3.7 1 1 2 3 3 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1272 PF06906.11 KNZ72904.1 - 0.058 13.5 4.2 0.15 12.2 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 KNZ72904.1 - 0.059 13.3 0.5 1.2 9.0 1.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1192 PF06698.11 KNZ72904.1 - 0.13 12.4 0.1 0.13 12.4 0.1 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1192) zf-RING_4 PF14570.6 KNZ72904.1 - 0.64 9.9 10.0 3.1 7.7 6.5 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KNZ72904.1 - 0.73 10.0 7.4 1.7 8.9 7.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 KNZ72904.1 - 2.5 8.0 5.0 6 6.8 5.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ureidogly_lyase PF04115.12 KNZ72905.1 - 1.7e-47 161.6 0.0 2.2e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase Allantoicase PF03561.15 KNZ72905.1 - 1.1e-37 129.2 0.2 1.6e-37 128.7 0.2 1.3 1 0 0 1 1 1 1 Allantoicase repeat Methyltransf_31 PF13847.6 KNZ72906.1 - 1.9e-05 24.5 0.0 3.4e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ72906.1 - 5.4e-05 22.8 0.3 0.00046 19.8 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase small domain PrmC_N PF17827.1 KNZ72906.1 - 0.00013 22.5 0.9 0.0003 21.3 0.1 2.1 2 1 0 2 2 2 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 KNZ72906.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KNZ72906.1 - 0.00044 19.8 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 KNZ72906.1 - 0.0016 19.1 0.0 0.0032 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ72906.1 - 0.16 12.6 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 KNZ72906.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.5 1 1 0 1 1 1 0 RNA methyltransferase Zn_clus PF00172.18 KNZ72907.1 - 0.00028 20.9 11.8 0.0006 19.9 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KNZ72907.1 - 0.0042 17.1 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold Frankia_peptide PF14407.6 KNZ72907.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. PRA1 PF03208.19 KNZ72908.1 - 2.4e-33 114.8 0.5 2.9e-33 114.5 0.5 1.0 1 0 0 1 1 1 1 PRA1 family protein MPS-4 PF17523.2 KNZ72908.1 - 0.021 14.9 0.3 0.047 13.8 0.3 1.7 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 DUF202 PF02656.15 KNZ72908.1 - 3.8 8.0 6.8 1 9.8 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Asp-B-Hydro_N PF05279.11 KNZ72909.1 - 0.022 14.8 0.4 0.027 14.5 0.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TPR_1 PF00515.28 KNZ72910.1 - 3.9e-17 61.3 7.6 3.7e-05 23.3 0.2 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ72910.1 - 6.2e-14 50.9 11.1 0.0011 18.9 0.3 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ72910.1 - 3.1e-10 40.0 9.5 0.00084 20.0 0.1 5.6 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ72910.1 - 1.6e-09 37.3 3.2 0.0053 16.4 0.5 4.3 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 KNZ72910.1 - 7e-09 35.8 9.7 0.00039 20.6 0.6 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72910.1 - 3.4e-08 33.3 8.3 0.18 12.3 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ72910.1 - 1.7e-07 31.8 4.5 0.00028 21.5 0.4 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72910.1 - 2e-07 30.7 5.2 0.17 12.2 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ72910.1 - 2.5e-07 31.1 9.1 6.4e-06 26.6 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 KNZ72910.1 - 1e-05 25.7 6.4 0.44 10.9 1.2 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72910.1 - 0.00021 21.4 3.5 0.016 15.4 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ72910.1 - 0.0017 18.5 3.8 0.011 16.0 0.7 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KNZ72910.1 - 0.048 13.7 3.4 5.1 7.4 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ72910.1 - 0.088 12.7 11.4 1 9.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 KNZ72911.1 - 8.2e-13 48.0 12.6 0.00034 20.9 0.3 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ72911.1 - 1.1e-07 32.1 11.6 0.026 15.4 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ72911.1 - 5.7e-06 26.5 15.1 9.6e-05 22.6 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 KNZ72911.1 - 3.6e-05 23.6 6.2 0.01 15.9 0.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 KNZ72911.1 - 0.011 16.4 13.9 1 10.0 4.2 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain zf-Di19 PF05605.12 KNZ72911.1 - 0.012 15.9 3.7 0.42 10.9 2.1 2.4 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KNZ72911.1 - 0.014 15.7 4.8 3.4 8.2 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type OSTMP1 PF09777.9 KNZ72911.1 - 0.043 13.2 0.3 0.06 12.7 0.3 1.1 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor zf-C2H2_2 PF12756.7 KNZ72911.1 - 0.055 13.8 2.2 1.7 9.0 1.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 KNZ72911.1 - 0.12 12.4 7.0 0.09 12.8 2.1 2.4 2 0 0 2 2 2 0 BED zinc finger zf-TRAF PF02176.18 KNZ72911.1 - 0.5 11.1 7.0 0.14 12.9 2.3 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger Abhydrolase_3 PF07859.13 KNZ72912.1 - 8.7e-30 104.1 0.0 2.4e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PspC PF04024.12 KNZ72912.1 - 6.1 6.8 5.2 0.84 9.5 0.7 1.9 2 0 0 2 2 2 0 PspC domain IF-2B PF01008.17 KNZ72913.1 - 2.9e-52 177.6 0.0 3.8e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Retrotran_gag_2 PF14223.6 KNZ72914.1 - 8e-14 51.5 0.0 1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TNV_CP PF03898.13 KNZ72914.1 - 0.058 12.7 0.1 0.078 12.2 0.1 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein TrbC_Ftype PF09673.10 KNZ72914.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Asparaginase_2 PF01112.18 KNZ72915.1 - 3.7e-39 134.5 0.0 6.7e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Asparaginase Tfb4 PF03850.14 KNZ72916.1 - 1.7e-82 277.0 0.0 2e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 SNF2_N PF00176.23 KNZ72917.1 - 3.7e-60 203.5 0.2 5.9e-60 202.8 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 KNZ72917.1 - 2.9e-24 85.3 0.3 1.1e-23 83.5 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 KNZ72917.1 - 2.9e-19 68.7 7.5 2.9e-16 59.1 1.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 KNZ72917.1 - 3.2e-19 69.3 0.0 9.3e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cdh1_DBD_1 PF18196.1 KNZ72917.1 - 1.8e-09 38.0 0.2 1.8e-09 38.0 0.2 3.5 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 HDA2-3 PF11496.8 KNZ72917.1 - 8.2e-09 35.0 0.5 1.7e-08 34.0 0.5 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KNZ72917.1 - 3.7e-07 30.3 0.0 9.8e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 KNZ72917.1 - 4.8e-06 27.2 2.7 7.3e-06 26.6 0.3 2.6 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 ERCC3_RAD25_C PF16203.5 KNZ72917.1 - 0.00011 21.6 0.4 0.00022 20.6 0.4 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-C2H2_3rep PF18868.1 KNZ72917.1 - 0.037 14.7 0.7 1.2 9.9 0.0 3.4 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Methyltransf_18 PF12847.7 KNZ72917.1 - 0.075 13.0 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF1771 PF08590.10 KNZ72918.1 - 0.00029 21.2 3.8 0.00056 20.2 3.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Slu7 PF11708.8 KNZ72919.1 - 9.9e-108 360.0 12.6 9.9e-108 360.0 12.6 2.0 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor XPG_N PF00752.17 KNZ72920.1 - 4.7e-34 116.9 0.0 9.4e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KNZ72920.1 - 4.7e-25 87.8 0.0 1.3e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 KNZ72920.1 - 4.3e-08 33.7 0.0 1.2e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 KNZ72920.1 - 0.0055 17.3 0.1 0.027 15.1 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain Fungal_trans PF04082.18 KNZ72922.1 - 6.6e-29 100.8 0.0 1.6e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ72922.1 - 0.18 12.0 1.3 0.38 10.9 1.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H2-Ydr279 PF09468.10 KNZ72923.1 - 5.4e-20 72.2 0.0 2.2e-19 70.2 0.0 2.1 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KNZ72923.1 - 1.5e-14 54.0 0.2 1.3e-13 50.9 0.0 2.9 3 0 0 3 3 3 1 Ydr279p protein triple barrel domain MmgE_PrpD PF03972.14 KNZ72924.1 - 4.8e-154 513.1 0.0 5.6e-154 512.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ATP-sulfurylase PF01747.17 KNZ72925.1 - 1.5e-88 295.8 0.1 2.1e-88 295.3 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 KNZ72925.1 - 5.6e-52 175.6 0.0 9.1e-52 174.9 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 KNZ72925.1 - 1.1e-49 168.3 0.0 1.6e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PspC PF04024.12 KNZ72926.1 - 3.2 7.6 5.7 0.5 10.2 1.8 1.6 2 0 0 2 2 2 0 PspC domain ERO1 PF04137.15 KNZ72927.1 - 3.5e-127 424.5 0.2 4.1e-127 424.2 0.2 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) KH_1 PF00013.29 KNZ72928.1 - 4e-82 270.0 28.8 2.4e-12 46.5 0.1 15.1 15 2 0 15 15 15 9 KH domain SLS PF14611.6 KNZ72928.1 - 4e-10 39.9 18.3 0.017 15.0 0.1 6.5 6 0 0 6 6 6 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KNZ72928.1 - 7.3e-10 38.5 20.6 0.012 15.4 1.3 8.0 8 0 0 8 8 8 4 KH domain MOEP19 PF16005.5 KNZ72928.1 - 0.0006 19.8 0.0 0.082 12.9 0.0 3.8 3 0 0 3 3 3 1 KH-like RNA-binding domain DUF4974 PF16344.5 KNZ72928.1 - 0.00065 19.7 0.1 0.022 14.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4974) KH_4 PF13083.6 KNZ72928.1 - 0.054 13.4 16.4 2.3 8.2 0.2 6.9 7 0 0 7 7 7 0 KH domain DUF5629 PF18629.1 KNZ72928.1 - 0.31 11.6 1.3 0.63 10.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5629) BMC PF00936.19 KNZ72928.1 - 0.8 9.7 26.2 0.72 9.9 0.6 6.7 7 0 0 7 7 7 0 BMC domain RRM_1 PF00076.22 KNZ72929.1 - 1.9e-09 37.2 0.0 0.00018 21.3 0.0 2.7 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 KNZ72929.1 - 1e-08 35.0 0.2 2.5e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 Surp module RRM_7 PF16367.5 KNZ72929.1 - 0.0085 16.2 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif CTD_bind PF04818.13 KNZ72929.1 - 0.025 15.4 0.1 0.07 14.0 0.1 1.9 1 0 0 1 1 1 0 RNA polymerase II-binding domain. TonB_N PF16031.5 KNZ72929.1 - 0.054 14.0 0.4 0.054 14.0 0.4 1.9 3 0 0 3 3 3 0 TonB polyproline region CTNNB1_binding PF08347.11 KNZ72929.1 - 0.82 9.8 5.4 1.7 8.8 5.4 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding PPP5 PF08321.12 KNZ72930.1 - 1e-26 93.0 0.1 2.2e-26 92.0 0.1 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 KNZ72930.1 - 5e-25 89.2 0.1 9.6e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 KNZ72930.1 - 3.8e-16 58.1 4.0 3.1e-07 29.9 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ72930.1 - 2.5e-12 45.9 3.9 0.00026 20.9 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ72930.1 - 6.9e-10 38.5 0.2 0.057 13.1 0.0 3.5 3 0 0 3 3 3 3 TPR repeat TPR_17 PF13431.6 KNZ72930.1 - 4e-09 36.2 0.7 0.00064 19.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ72930.1 - 3.6e-08 33.4 0.0 0.00065 19.8 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ72930.1 - 1.5e-06 28.6 0.7 0.75 10.4 0.3 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ72930.1 - 6.3e-05 22.9 3.0 0.065 13.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ72930.1 - 0.0004 21.0 0.4 0.64 11.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ72930.1 - 0.003 18.2 3.0 0.26 12.0 1.5 2.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ72930.1 - 0.015 14.5 0.4 0.04 13.1 0.5 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ72930.1 - 0.029 15.0 1.7 0.11 13.2 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ72930.1 - 0.048 13.7 0.1 4.1 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SLT PF01464.20 KNZ72931.1 - 2.9e-14 52.7 0.1 6e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 KNZ72931.1 - 0.02 15.4 1.5 0.062 13.8 0.6 2.3 2 1 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase P_C PF06640.11 KNZ72931.1 - 0.069 13.3 0.7 0.11 12.6 0.7 1.3 1 0 0 1 1 1 0 P protein C-terminus Cyclin PF08613.11 KNZ72932.1 - 0.00076 19.9 0.0 0.016 15.6 0.0 2.6 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 KNZ72932.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Cyclin, N-terminal domain Asp PF00026.23 KNZ72933.1 - 8.2e-42 143.7 0.2 1e-41 143.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ72933.1 - 2e-06 28.1 3.8 0.00011 22.5 3.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ72933.1 - 0.0056 17.3 2.5 2.5 8.8 0.0 3.5 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ72933.1 - 0.16 12.5 0.3 25 5.5 0.0 2.9 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Zn_clus PF00172.18 KNZ72934.1 - 4e-07 30.1 6.7 6e-07 29.5 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KNZ72935.1 - 5.7e-63 212.7 0.0 6.6e-63 212.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72935.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ72935.1 - 0.00014 20.7 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KNZ72935.1 - 0.00022 20.7 0.0 0.0015 18.0 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Acetyltransf_1 PF00583.25 KNZ72936.1 - 2.8e-13 50.1 0.0 3.6e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ72936.1 - 1.7e-08 34.7 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ72936.1 - 2.3e-06 27.6 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNZ72936.1 - 7.6e-05 22.9 0.0 9.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ72936.1 - 0.0076 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 KNZ72936.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNZ72936.1 - 0.11 13.2 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 KNZ72936.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.24 KNZ72939.1 - 1.2e-28 100.2 26.9 5.5e-19 68.4 5.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ72939.1 - 4.1e-18 65.4 33.3 4.9e-18 65.2 30.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Complex1_49kDa PF00346.19 KNZ72940.1 - 4.7e-108 360.4 0.0 6.5e-108 359.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KNZ72940.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Pkinase PF00069.25 KNZ72941.1 - 9.5e-22 77.6 0.0 1.1e-19 70.8 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72941.1 - 4.2e-07 29.5 0.0 0.00032 20.1 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ72941.1 - 0.01 15.2 0.0 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 KNZ72941.1 - 0.019 14.3 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2201 PF09967.9 KNZ72941.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 VWA-like domain (DUF2201) RIO1 PF01163.22 KNZ72941.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family iPGM_N PF06415.13 KNZ72942.1 - 5.3e-74 248.3 0.0 1.1e-73 247.2 0.0 1.6 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KNZ72942.1 - 3.5e-72 242.7 0.7 5.1e-72 242.2 0.7 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KNZ72942.1 - 9.3e-07 28.5 0.1 5.6e-06 26.0 0.1 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KNZ72942.1 - 3.5e-05 23.6 0.0 7.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 KNZ72942.1 - 0.0022 18.1 0.1 0.0055 16.8 0.1 1.7 1 0 0 1 1 1 1 PglZ domain Alk_phosphatase PF00245.20 KNZ72942.1 - 0.011 14.8 0.7 0.022 13.7 0.4 1.6 2 0 0 2 2 2 0 Alkaline phosphatase ATG27 PF09451.10 KNZ72943.1 - 4.8e-14 52.9 0.0 1.7e-13 51.1 0.0 1.7 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 KNZ72943.1 - 1.4e-09 37.5 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 KNZ72943.1 - 1.7e-09 37.9 0.0 0.00068 19.7 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat NIF3 PF01784.18 KNZ72944.1 - 3.7e-53 180.7 0.1 1.6e-50 172.0 0.1 2.7 2 1 0 2 2 2 2 NIF3 (NGG1p interacting factor 3) ECH_1 PF00378.20 KNZ72945.1 - 7.4e-51 172.9 0.0 1e-50 172.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ72945.1 - 3.1e-21 76.2 0.0 6.8e-21 75.1 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_M76 PF09768.9 KNZ72946.1 - 2.8e-69 232.3 2.2 3.4e-69 232.0 2.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 KNZ72946.1 - 0.57 10.1 3.5 1.3 8.9 3.3 1.6 1 1 0 1 1 1 0 SprT-like family GPI-anchored PF10342.9 KNZ72947.1 - 2.3e-05 25.1 0.1 2.3e-05 25.1 0.1 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glutaredoxin PF00462.24 KNZ72948.1 - 2.5e-14 53.2 0.1 3.3e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KNZ72948.1 - 0.00037 20.9 0.2 0.00064 20.1 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KNZ72948.1 - 0.0047 16.9 0.0 0.0062 16.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF953 PF06110.11 KNZ72948.1 - 0.018 14.6 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DUF836 PF05768.14 KNZ72948.1 - 0.06 13.8 0.0 0.073 13.5 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DPM3 PF08285.11 KNZ72949.1 - 1.2e-33 115.1 0.1 1.4e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TssO PF17561.2 KNZ72949.1 - 0.019 15.1 0.2 0.12 12.5 0.3 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO MTCP1 PF08991.10 KNZ72950.1 - 1.7e-13 50.6 7.2 2.7e-13 49.9 7.2 1.3 1 1 0 1 1 1 1 Mature-T-Cell Proliferation I type HsbA PF12296.8 KNZ72953.1 - 5e-15 56.0 1.0 5e-15 56.0 1.0 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A UDPG_MGDP_dh PF00984.19 KNZ72953.1 - 0.042 14.1 0.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain RVT_1 PF00078.27 KNZ72956.1 - 2.4e-05 24.0 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Haemagg_act PF05860.13 KNZ72956.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 haemagglutination activity domain DUF5337 PF17272.2 KNZ72958.1 - 0.027 14.3 4.1 0.071 12.9 0.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Fasciclin PF02469.22 KNZ72959.1 - 5.1e-07 30.0 0.0 1.2e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain ICMT PF04140.14 KNZ72960.1 - 6.7e-12 45.7 0.2 6.7e-12 45.7 0.2 2.5 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KNZ72960.1 - 1.5e-10 41.4 2.7 9.6e-10 38.8 0.4 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KNZ72960.1 - 4.6e-05 22.4 0.2 6.4e-05 21.9 0.2 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KNZ72960.1 - 0.0093 15.5 0.5 0.018 14.6 0.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Aldo_ket_red PF00248.21 KNZ72962.1 - 6.3e-65 219.3 0.0 7.3e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adap_comp_sub PF00928.21 KNZ72963.1 - 1.1e-21 77.5 0.0 2e-21 76.5 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KNZ72963.1 - 2.8e-06 27.3 0.3 4.4e-06 26.7 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phytoreo_Pns PF05451.11 KNZ72963.1 - 0.07 12.3 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 DUF4337 PF14235.6 KNZ72963.1 - 0.56 10.3 2.2 0.93 9.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Rib_hydrolayse PF02267.17 KNZ72964.1 - 0.0023 17.4 0.1 0.0031 17.0 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosyl cyclase TPR_10 PF13374.6 KNZ72967.1 - 5e-27 93.0 0.6 2.9e-08 33.3 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ72967.1 - 1.8e-23 82.6 2.0 5.2e-12 45.9 0.4 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ72967.1 - 2.2e-07 30.8 0.0 0.012 16.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ72967.1 - 0.00027 21.3 1.7 7.9 7.4 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ72967.1 - 0.0056 17.3 5.0 1.6 9.4 0.3 3.0 1 1 2 3 3 3 2 Domain of unknown function (DUF4404) TPR_MalT PF17874.1 KNZ72967.1 - 0.011 15.2 3.7 0.029 13.7 3.4 1.7 1 1 0 1 1 1 0 MalT-like TPR region Lipase_chap PF03280.14 KNZ72967.1 - 0.018 15.0 1.4 1.1 9.2 0.1 2.2 1 1 1 2 2 2 0 Proteobacterial lipase chaperone protein DUF919 PF06034.11 KNZ72967.1 - 0.028 14.2 0.7 9.4 6.2 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) FAD_binding_8 PF08022.12 KNZ72967.1 - 0.031 14.3 0.1 0.32 11.1 0.0 2.2 1 1 1 2 2 2 0 FAD-binding domain TPR_19 PF14559.6 KNZ72967.1 - 0.033 14.7 1.0 0.17 12.4 0.4 2.4 2 2 1 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.22 KNZ72968.1 - 5.5e-18 64.6 0.0 7.6e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNZ72968.1 - 0.0022 17.6 0.0 0.0031 17.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KNZ72971.1 - 5.8e-08 32.2 1.8 5.8e-08 32.2 1.8 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 KNZ72971.1 - 1.1e-07 32.1 7.9 3e-07 30.8 3.3 2.5 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Adaptin_N PF01602.20 KNZ72972.1 - 2e-92 310.5 6.1 3.4e-92 309.7 6.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 KNZ72972.1 - 1.9e-59 199.2 0.0 5.6e-59 197.7 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 KNZ72972.1 - 1.4e-53 180.6 0.0 3.3e-53 179.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 KNZ72972.1 - 1.2e-10 41.6 0.1 0.091 13.2 0.0 5.5 1 1 4 5 5 5 3 HEAT repeats Cnd1 PF12717.7 KNZ72972.1 - 4.2e-08 33.4 9.9 0.00045 20.3 0.0 4.5 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 KNZ72972.1 - 2e-06 27.4 8.9 0.00053 19.5 1.6 3.8 2 2 3 5 5 5 3 Family of unknown function (DUF5578) Coatomer_g_Cpla PF16381.5 KNZ72972.1 - 4.8e-06 26.7 0.1 0.00078 19.6 0.0 2.8 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KNZ72972.1 - 3.9e-05 23.5 1.2 1.3 9.5 0.0 5.3 5 0 0 5 5 4 1 HEAT repeat DUF5071 PF16804.5 KNZ72972.1 - 0.0018 18.6 0.8 0.14 12.4 0.0 3.7 1 1 3 4 4 4 1 Domain of unknown function (DUF5071) RTP1_C1 PF10363.9 KNZ72972.1 - 0.0054 16.9 1.4 1 9.5 0.0 3.2 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 ParcG PF10274.9 KNZ72972.1 - 0.0087 16.2 2.1 0.88 9.7 0.0 3.0 3 1 0 3 3 3 1 Parkin co-regulated protein MA3 PF02847.17 KNZ72972.1 - 0.038 14.0 0.5 3.8 7.5 0.0 3.3 2 0 0 2 2 2 0 MA3 domain RasGEF_N_2 PF14663.6 KNZ72972.1 - 0.041 14.3 7.0 2.6 8.5 0.0 5.0 5 1 1 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Gemini_V2 PF01524.17 KNZ72972.1 - 0.16 12.2 0.1 4 7.7 0.0 2.6 2 0 0 2 2 2 0 Geminivirus V2 protein Utp14 PF04615.13 KNZ72973.1 - 1.1e-197 659.2 56.9 1.1e-197 659.2 56.9 2.0 1 1 1 2 2 2 1 Utp14 protein Pkinase PF00069.25 KNZ72974.1 - 1.4e-73 247.5 0.0 1.8e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ72974.1 - 3.9e-40 137.8 0.0 5.6e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KNZ72974.1 - 1.8e-17 63.8 0.9 2.1e-10 41.1 0.0 3.4 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KNZ72974.1 - 1.2e-13 50.9 0.1 2.6e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KNZ72974.1 - 2.6e-06 26.9 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KNZ72974.1 - 8.8e-05 22.2 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KNZ72974.1 - 0.00013 21.1 0.3 0.00023 20.2 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KNZ72974.1 - 0.0003 20.2 0.8 0.0065 15.8 0.8 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ72974.1 - 0.079 12.9 0.6 0.33 10.8 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.9 KNZ72974.1 - 0.18 10.6 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC MatE PF01554.18 KNZ72977.1 - 5.1e-42 143.3 22.8 1.4e-21 76.8 8.1 2.3 2 0 0 2 2 2 2 MatE Heme_oxygenase PF01126.20 KNZ72978.1 - 0.0092 15.8 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Heme oxygenase DHR10 PF18595.1 KNZ72978.1 - 0.67 10.0 22.3 0.5 10.4 1.5 3.2 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain HALZ PF02183.18 KNZ72978.1 - 0.76 10.1 9.3 1.2 9.4 0.8 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper APG6_N PF17675.1 KNZ72978.1 - 1.4 9.5 24.0 11 6.6 14.4 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region PhoU PF01895.19 KNZ72978.1 - 1.4 9.4 7.8 0.57 10.7 1.0 2.9 2 1 1 3 3 3 0 PhoU domain Asp PF00026.23 KNZ72979.1 - 1.3e-45 156.2 6.0 1.9e-45 155.7 6.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ72979.1 - 6.1e-08 33.1 5.3 3.3e-06 27.5 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ72979.1 - 1.6e-05 25.4 3.4 9.6e-05 23.0 0.8 2.8 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ72979.1 - 0.0018 18.8 1.3 0.0089 16.6 0.1 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KNZ72979.1 - 0.11 12.3 0.0 0.59 9.9 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal WD40 PF00400.32 KNZ72982.1 - 0.019 15.8 16.5 2 9.4 0.4 6.0 6 1 0 6 6 6 0 WD domain, G-beta repeat Clusterin PF01093.17 KNZ72983.1 - 0.077 12.0 0.0 0.097 11.7 0.0 1.1 1 0 0 1 1 1 0 Clusterin TP_methylase PF00590.20 KNZ72984.1 - 7.9e-42 143.6 1.7 1.3e-41 142.9 1.7 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 KNZ72984.1 - 3.8e-09 35.8 0.1 8e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 KNZ72984.1 - 4.8e-09 35.7 2.2 3.7e-06 26.5 0.1 2.8 3 0 0 3 3 3 2 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.6 KNZ72984.1 - 0.00034 21.0 0.0 0.0015 18.9 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding SRP14 PF02290.15 KNZ72985.1 - 1.1e-22 80.1 1.3 1.4e-22 79.9 0.0 1.7 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF726 PF05277.12 KNZ72989.1 - 5e-121 403.8 0.9 6.8e-121 403.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) LCAT PF02450.15 KNZ72989.1 - 0.18 11.0 0.6 0.27 10.3 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Glyco_hydro_43 PF04616.14 KNZ72990.1 - 1.1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1115 PF06544.12 KNZ72991.1 - 9.2e-06 25.8 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) AKAP95 PF04988.12 KNZ72991.1 - 0.037 14.3 0.1 0.068 13.4 0.1 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) MtN3_slv PF03083.16 KNZ72992.1 - 0.037 14.1 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange MatE PF01554.18 KNZ72993.1 - 1.2e-31 109.5 27.3 1.2e-24 86.8 9.4 3.4 2 1 1 3 3 3 3 MatE Aminotran_1_2 PF00155.21 KNZ72994.1 - 8.3e-42 143.6 0.0 9.3e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNZ72994.1 - 3e-06 26.8 0.1 4.6e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KNZ72994.1 - 0.00031 19.4 0.0 0.00046 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KNZ72994.1 - 0.023 13.7 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Malic_M PF03949.15 KNZ72996.1 - 1.8e-84 283.1 0.0 2.3e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KNZ72996.1 - 3.7e-61 206.1 0.0 1.6e-60 204.0 0.0 1.9 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain MARVEL PF01284.23 KNZ72997.1 - 9.6e-06 25.7 17.4 1.2e-05 25.4 17.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_U4 PF03419.13 KNZ72997.1 - 2.3 7.4 13.0 2.8 7.1 13.0 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Fungal_trans PF04082.18 KNZ72998.1 - 1.1e-11 44.3 1.9 2e-11 43.4 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ72998.1 - 2.6e-05 24.3 10.2 6.6e-05 22.9 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4215 PF13948.6 KNZ72998.1 - 0.11 12.9 0.3 0.23 11.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) DUF2235 PF09994.9 KNZ72999.1 - 2.3e-92 309.4 0.0 2.8e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_28 PF00295.17 KNZ73000.1 - 1.4e-42 145.9 1.6 1.4e-42 145.9 1.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KNZ73000.1 - 1.5 8.7 18.2 0.71 9.7 10.4 2.7 1 1 1 2 2 2 0 Right handed beta helix region Histone PF00125.24 KNZ73001.1 - 1.6e-45 154.7 1.3 2.1e-45 154.3 1.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNZ73001.1 - 6.8e-05 23.2 0.1 0.00011 22.5 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNZ73001.1 - 0.00022 21.3 0.9 0.00029 20.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KNZ73001.1 - 0.0038 17.5 0.1 0.0038 17.5 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cellulase PF00150.18 KNZ73002.1 - 2.8e-31 109.0 6.5 3.6e-31 108.6 6.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KNZ73002.1 - 1.2e-11 44.3 6.7 1.2e-11 44.3 6.7 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 KNZ73002.1 - 5.2e-08 32.3 0.0 8.9e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 KNZ73002.1 - 2e-05 24.4 1.2 2.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 KNZ73002.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_10 PF00331.20 KNZ73002.1 - 0.014 14.5 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 SlpA PF03217.14 KNZ73002.1 - 0.082 13.5 0.0 19 5.9 0.0 2.7 2 0 0 2 2 2 0 Surface later protein A domain zf-C2H2_4 PF13894.6 KNZ73004.1 - 0.00055 20.5 1.8 0.36 11.8 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ73004.1 - 0.016 15.7 1.7 1.8 9.2 0.1 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 KNZ73004.1 - 0.028 14.3 1.9 0.096 12.6 1.9 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type L51_S25_CI-B8 PF05047.16 KNZ73004.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-4CXXC_R1 PF10497.9 KNZ73004.1 - 0.57 10.4 4.0 0.92 9.8 4.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 GFO_IDH_MocA PF01408.22 KNZ73005.1 - 1.7e-14 54.7 0.0 3.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KNZ73005.1 - 0.0022 18.0 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain F-box-like PF12937.7 KNZ73006.1 - 3.3e-10 39.7 0.6 8.4e-10 38.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 KNZ73006.1 - 0.00061 19.5 0.6 6.6 6.6 0.0 4.4 4 1 0 4 4 4 2 Leucine rich repeat Colicin_M PF14859.6 KNZ73006.1 - 0.21 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Colicin M p450 PF00067.22 KNZ73007.1 - 6.4e-71 239.5 0.0 7.2e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.9 KNZ73009.1 - 8.5e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KNZ73009.1 - 6.4e-05 23.6 0.0 0.00024 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ73009.1 - 0.00011 22.9 0.0 0.00027 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73009.1 - 0.00041 20.2 0.0 0.0022 17.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ73009.1 - 0.0045 16.8 0.0 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ73009.1 - 0.038 14.6 0.0 0.085 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCHC PF00098.23 KNZ73013.1 - 0.032 14.3 0.7 0.032 14.3 0.7 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ73013.1 - 0.04 13.6 0.6 0.072 12.8 0.6 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger gag-asp_proteas PF13975.6 KNZ73014.1 - 0.0064 17.0 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ73014.1 - 0.059 14.0 0.0 0.092 13.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease PHY PF00360.20 KNZ73017.1 - 2.4e-28 98.7 0.0 5.3e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 KNZ73017.1 - 1.6e-18 67.3 0.0 3.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KNZ73017.1 - 4.1e-18 65.6 0.2 1.1e-17 64.2 0.2 1.8 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 KNZ73017.1 - 8.9e-15 55.5 0.0 1.4e-13 51.6 0.0 2.5 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 KNZ73017.1 - 4.6e-09 36.9 0.2 5.1e-08 33.5 0.0 2.9 3 0 0 3 3 3 1 PAS fold Abhydrolase_6 PF12697.7 KNZ73017.1 - 8.4e-08 33.1 0.1 3.5e-07 31.1 0.1 2.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ73017.1 - 1.1e-07 31.8 0.1 7.7e-07 29.0 0.1 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ73017.1 - 1.3e-06 27.8 0.1 3.5e-05 23.2 0.1 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 HisKA PF00512.25 KNZ73017.1 - 1.3e-05 25.1 0.2 4e-05 23.6 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Abhydrolase_3 PF07859.13 KNZ73017.1 - 0.00077 19.4 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold HATPase_c_3 PF13589.6 KNZ73017.1 - 0.0063 16.3 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3089 PF11288.8 KNZ73017.1 - 0.039 13.5 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) OKR_DC_1_N PF03709.15 KNZ73017.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain HCO3_cotransp PF00955.21 KNZ73018.1 - 1.5e-76 258.3 10.1 4.9e-42 144.4 0.2 2.0 1 1 1 2 2 2 2 HCO3- transporter family Sulfate_transp PF00916.20 KNZ73018.1 - 0.0003 19.7 6.5 0.0004 19.3 1.0 2.9 3 0 0 3 3 3 1 Sulfate permease family DUF3522 PF12036.8 KNZ73018.1 - 0.095 13.0 7.8 0.53 10.5 1.6 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) His_Phos_2 PF00328.22 KNZ73019.1 - 2.2e-05 24.0 0.3 0.0037 16.7 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.22 KNZ73019.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Iwr1 PF08574.10 KNZ73020.1 - 1.7e-11 44.9 11.1 1.7e-11 44.9 11.1 2.9 3 0 0 3 3 3 1 Transcription factor Iwr1 cobW PF02492.19 KNZ73021.1 - 6e-25 87.8 0.0 7.4e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 KNZ73021.1 - 0.0036 17.4 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TIP49 PF06068.13 KNZ73021.1 - 0.01 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain ABC_tran PF00005.27 KNZ73021.1 - 0.033 14.7 0.0 0.049 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KNZ73021.1 - 0.06 12.4 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 KNZ73021.1 - 0.066 13.8 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ73021.1 - 0.07 13.5 0.0 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 KNZ73021.1 - 0.073 13.6 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KNZ73021.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 KNZ73021.1 - 0.083 12.9 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TsaE PF02367.17 KNZ73021.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KNZ73021.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KNZ73021.1 - 0.2 12.0 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HVSL PF09749.9 KNZ73022.1 - 1.7e-43 148.9 2.5 3.9e-43 147.7 2.5 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 KNZ73022.1 - 2e-05 24.6 2.0 2.6e-05 24.2 1.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily RNase_H PF00075.24 KNZ73023.1 - 2.5e-06 27.7 0.1 5.9e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 RNase H UAA PF08449.11 KNZ73024.1 - 2.6e-76 256.7 15.3 3e-76 256.5 15.3 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KNZ73024.1 - 3.1e-06 26.6 1.9 4.8e-06 26.0 1.9 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KNZ73024.1 - 1.6e-05 25.1 26.8 0.012 15.8 9.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 KNZ73024.1 - 0.00038 19.8 3.5 0.00038 19.8 3.5 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 KNZ73024.1 - 0.00062 18.8 6.0 0.00086 18.4 1.7 2.2 1 1 1 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Mur_ligase_M PF08245.12 KNZ73025.1 - 4.5e-06 26.8 0.0 0.00032 20.7 0.0 2.6 2 1 0 2 2 2 2 Mur ligase middle domain Methyltransf_11 PF08241.12 KNZ73026.1 - 1.6e-20 73.5 0.0 3.5e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73026.1 - 1.1e-19 70.7 0.0 1.5e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ73026.1 - 2.3e-18 66.7 0.0 1.2e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ73026.1 - 1.5e-17 63.9 0.0 2.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73026.1 - 2.1e-14 54.1 0.0 3.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ73026.1 - 5.4e-12 45.6 0.0 1.9e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KNZ73026.1 - 7.7e-09 35.3 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KNZ73026.1 - 5.7e-07 28.8 0.0 7.9e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 KNZ73026.1 - 9.5e-06 25.5 0.1 1.9e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KNZ73026.1 - 5e-05 22.8 0.0 7.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KNZ73026.1 - 0.00036 20.2 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KNZ73026.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KNZ73026.1 - 0.0012 18.2 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 KNZ73026.1 - 0.0034 16.5 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase ADH_zinc_N PF00107.26 KNZ73026.1 - 0.0045 17.0 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UPF0020 PF01170.18 KNZ73026.1 - 0.018 14.8 0.5 0.13 11.9 0.3 2.3 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_7 PF03492.15 KNZ73026.1 - 0.027 13.7 0.0 23 4.0 0.0 3.1 3 0 0 3 3 3 0 SAM dependent carboxyl methyltransferase Styelin PF17562.2 KNZ73026.1 - 0.063 13.6 0.1 0.14 12.5 0.1 1.5 1 0 0 1 1 1 0 Styelin RRM_1 PF00076.22 KNZ73027.1 - 3.2e-06 26.8 0.0 6.5e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ73027.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KNZ73027.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KNZ73027.1 - 0.017 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif LRR_4 PF12799.7 KNZ73029.1 - 9e-27 92.7 26.4 0.00082 19.7 0.4 8.3 6 1 0 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ73029.1 - 3.5e-17 61.9 24.5 0.00035 20.3 0.0 6.9 3 1 5 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 KNZ73029.1 - 1.7e-14 53.7 1.2 0.004 16.7 0.0 4.3 2 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 KNZ73029.1 - 0.018 15.5 33.7 42 5.2 0.2 11.0 9 4 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KNZ73029.1 - 0.05 13.7 15.1 36 4.7 0.1 7.7 9 0 0 9 9 9 0 Leucine Rich repeat Mem_trans PF03547.18 KNZ73031.1 - 0.2 10.0 0.6 0.24 9.7 0.6 1.1 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.15 KNZ73031.1 - 0.28 9.9 6.3 0.34 9.6 6.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.9 KNZ73031.1 - 0.44 9.3 9.5 0.51 9.1 9.5 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.13 KNZ73031.1 - 0.98 9.3 16.8 1.1 9.1 16.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Menin PF05053.13 KNZ73031.1 - 2.5 6.4 10.0 3 6.1 10.0 1.1 1 0 0 1 1 1 0 Menin RR_TM4-6 PF06459.12 KNZ73031.1 - 2.6 7.8 8.8 3.5 7.4 8.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 KNZ73031.1 - 2.8 6.8 6.4 3.2 6.7 6.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ndc1_Nup PF09531.10 KNZ73031.1 - 3.9 6.0 9.1 4.6 5.8 9.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SpoIIIAH PF12685.7 KNZ73031.1 - 5.9 6.7 15.8 8.1 6.2 15.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Hid1 PF12722.7 KNZ73031.1 - 6.5 4.7 8.8 7.1 4.6 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MGC-24 PF05283.11 KNZ73031.1 - 6.6 7.2 14.9 14 6.1 14.8 1.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Apt1 PF10351.9 KNZ73031.1 - 7.2 5.3 11.4 8 5.2 11.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mucin PF01456.17 KNZ73031.1 - 9.3 6.2 14.0 13 5.7 14.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF202 PF02656.15 KNZ73032.1 - 4e-17 62.4 2.3 4e-17 62.4 2.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PMP22_Claudin PF00822.20 KNZ73032.1 - 0.36 10.7 2.9 0.62 9.9 2.9 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family SET PF00856.28 KNZ73033.1 - 1.8e-08 35.0 0.0 1.3e-07 32.2 0.0 2.2 1 1 0 1 1 1 1 SET domain NIPSNAP PF07978.13 KNZ73033.1 - 0.015 15.6 0.6 0.043 14.0 0.6 1.8 1 0 0 1 1 1 0 NIPSNAP FAD_binding_1 PF00667.20 KNZ73034.1 - 3.8e-53 180.3 0.0 2e-52 177.9 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KNZ73034.1 - 8.3e-32 110.4 0.5 1.6e-31 109.5 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KNZ73034.1 - 1.3e-19 70.8 0.0 4.2e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain She9_MDM33 PF05546.11 KNZ73035.1 - 2e-75 253.0 12.1 2e-75 253.0 12.1 1.4 1 1 0 1 1 1 1 She9 / Mdm33 family TACC_C PF05010.14 KNZ73035.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.9 2 1 1 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Uso1_p115_C PF04871.13 KNZ73035.1 - 0.78 10.1 9.6 0.27 11.6 1.2 2.9 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Lectin_N PF03954.14 KNZ73035.1 - 3.8 7.3 6.3 19 5.0 0.0 3.1 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain HSCB_C PF07743.13 KNZ73035.1 - 4.9 7.7 16.0 0.14 12.7 0.8 3.8 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Methyltransf_23 PF13489.6 KNZ73036.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain HIT PF01230.23 KNZ73037.1 - 7.3e-19 68.3 0.1 1.3e-18 67.5 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KNZ73037.1 - 4.7e-13 49.6 0.1 9.4e-13 48.6 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KNZ73037.1 - 0.00011 22.1 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CBFD_NFYB_HMF PF00808.23 KNZ73038.1 - 4.1e-15 55.8 2.1 4.1e-15 55.8 2.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ73038.1 - 1.7e-07 31.7 2.6 3.2e-07 30.8 2.6 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KNZ73038.1 - 0.033 14.3 0.3 0.061 13.4 0.3 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KNZ73038.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated MMS1_N PF10433.9 KNZ73039.1 - 5.7e-54 183.5 0.0 1e-53 182.7 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KNZ73039.1 - 1.7e-46 159.0 0.0 5.5e-46 157.4 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region Na_Ca_ex PF01699.24 KNZ73040.1 - 1.4e-20 73.8 41.4 9.9e-15 54.8 11.4 3.3 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Glyco_hydro_43 PF04616.14 KNZ73042.1 - 6.2e-37 127.5 3.2 7.5e-37 127.2 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ADH_N PF08240.12 KNZ73043.1 - 4.1e-25 87.8 0.5 8e-25 86.8 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ73043.1 - 8.7e-10 38.7 0.1 1.5e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ73043.1 - 0.065 14.3 0.2 0.49 11.4 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase Mon1 PF03164.14 KNZ73044.1 - 8.1e-97 324.8 0.0 1.8e-96 323.7 0.0 1.5 1 1 0 1 1 1 1 Trafficking protein Mon1 DUF3682 PF12446.8 KNZ73044.1 - 0.13 12.7 0.1 0.26 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) IGR PF09597.10 KNZ73045.1 - 0.00031 20.8 1.1 0.00053 20.0 1.1 1.4 1 0 0 1 1 1 1 IGR protein motif CRAL_TRIO PF00650.20 KNZ73046.1 - 1.9e-25 89.4 0.0 3e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ73046.1 - 7.3e-09 35.7 0.3 1.7e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Imm6 PF14434.6 KNZ73046.1 - 0.035 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein Imm6 DUF4376 PF14301.6 KNZ73046.1 - 0.16 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DUF4939 PF16297.5 KNZ73047.1 - 0.094 12.6 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Glyco_hydro_71 PF03659.14 KNZ73048.1 - 7.6e-123 410.0 3.6 9.4e-123 409.7 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 vATP-synt_AC39 PF01992.16 KNZ73049.1 - 3.5e-117 391.7 0.5 3.9e-117 391.5 0.5 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit TLP1_add_C PF18313.1 KNZ73049.1 - 0.039 13.9 0.0 0.16 11.9 0.0 1.9 1 1 1 2 2 2 0 Thiolase-like protein type 1 additional C-terminal domain MFS_1 PF07690.16 KNZ73050.1 - 6.9e-30 104.2 28.6 6.9e-30 104.2 28.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KNZ73050.1 - 0.2 11.5 5.0 17 5.2 3.5 2.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Shugoshin_C PF07557.11 KNZ73051.1 - 0.048 13.5 0.6 0.15 11.9 0.6 1.9 1 0 0 1 1 1 0 Shugoshin C terminus SQS_PSY PF00494.19 KNZ73052.1 - 2.5e-50 171.5 0.0 3.1e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_L28 PF00830.19 KNZ73053.1 - 5.3e-23 81.0 1.2 8.7e-23 80.3 1.2 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Complex1_LYR PF05347.15 KNZ73054.1 - 1.3e-07 31.5 0.1 1.7e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MRP-L47 PF06984.13 KNZ73055.1 - 4.2e-23 81.3 2.9 1.3e-22 79.7 2.9 1.9 1 1 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 KNZ73055.1 - 0.00066 19.6 2.7 0.00066 19.6 2.7 2.6 2 1 0 2 2 2 1 Ribosomal L29 protein SecD-TM1 PF13721.6 KNZ73055.1 - 0.4 11.2 1.8 2.9 8.4 0.1 2.2 1 1 1 2 2 2 0 SecD export protein N-terminal TM region RPN2_C PF18004.1 KNZ73055.1 - 1.1 9.2 8.1 2.5 8.0 8.1 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain AAA_23 PF13476.6 KNZ73056.1 - 8.3e-34 117.9 0.0 8.3e-34 117.9 0.0 8.0 1 1 1 2 2 1 1 AAA domain AAA_21 PF13304.6 KNZ73056.1 - 1.7e-11 44.5 5.8 3.9e-05 23.6 0.0 4.0 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNZ73056.1 - 1.4e-09 37.8 0.1 1.4e-09 37.8 0.1 4.8 4 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KNZ73056.1 - 7.4e-09 35.8 1.6 7.4e-09 35.8 1.6 5.9 1 1 3 4 4 2 2 AAA ATPase domain SbcCD_C PF13558.6 KNZ73056.1 - 1.6e-06 28.2 0.1 7.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KNZ73056.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KNZ73056.1 - 0.0038 17.7 0.1 0.0038 17.7 0.1 7.5 3 2 0 3 3 1 1 ABC transporter AAA_13 PF13166.6 KNZ73056.1 - 0.0071 15.0 0.0 0.0071 15.0 0.0 7.7 4 2 3 7 7 7 2 AAA domain Roc PF08477.13 KNZ73056.1 - 0.061 13.5 0.0 0.27 11.5 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KNZ73056.1 - 0.081 12.8 0.3 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Cyc-maltodext_C PF10438.9 KNZ73056.1 - 0.11 12.6 0.7 0.68 10.1 0.2 2.7 2 0 0 2 2 1 0 Cyclo-malto-dextrinase C-terminal domain AAA_16 PF13191.6 KNZ73056.1 - 0.22 11.9 0.0 0.22 11.9 0.0 4.0 4 1 0 5 5 5 0 AAA ATPase domain Jag_N PF14804.6 KNZ73056.1 - 0.47 10.8 6.1 10 6.5 0.2 4.3 3 0 0 3 3 3 0 Jag N-terminus GTP_EFTU PF00009.27 KNZ73056.1 - 1.1 8.7 6.2 0.34 10.4 0.0 3.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain SET PF00856.28 KNZ73057.1 - 6.6e-10 39.6 0.0 1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 KNZ73057.1 - 1.7e-07 31.2 14.7 1.7e-07 31.2 14.7 1.7 2 0 0 2 2 2 1 MYND finger DER1 PF04511.15 KNZ73058.1 - 2.7e-47 161.2 6.3 3e-47 161.0 6.3 1.0 1 0 0 1 1 1 1 Der1-like family NDK PF00334.19 KNZ73059.1 - 5.4e-17 62.1 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Tam41_Mmp37 PF09139.11 KNZ73060.1 - 2.3e-96 323.0 0.0 3e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Pkinase_fungal PF17667.1 KNZ73061.1 - 1.1e-15 57.3 0.0 1.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ATP-synt_C PF00137.21 KNZ73062.1 - 9.3e-19 67.5 11.3 9.3e-19 67.5 11.3 2.3 2 0 0 2 2 2 2 ATP synthase subunit C EHN PF06441.12 KNZ73063.1 - 1.2e-33 115.7 0.9 2.2e-32 111.6 0.0 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KNZ73063.1 - 1.1e-11 44.9 0.0 2.3e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ73063.1 - 0.0022 18.6 5.5 0.0095 16.6 5.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dynamin_N PF00350.23 KNZ73064.1 - 1.9e-19 70.4 0.1 5.3e-19 68.9 0.1 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KNZ73064.1 - 6.3e-14 52.0 0.1 4.9e-13 49.2 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNZ73064.1 - 2.1e-09 37.2 0.9 9.9e-09 35.0 0.5 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KNZ73064.1 - 2.5e-05 24.2 1.1 0.06 13.3 0.2 2.8 2 1 1 3 3 3 2 RsgA GTPase cobW PF02492.19 KNZ73064.1 - 0.00036 20.2 0.1 0.044 13.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KNZ73064.1 - 0.0027 17.9 0.2 0.53 10.5 0.0 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KNZ73064.1 - 0.003 16.7 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KNZ73064.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.18 KNZ73064.1 - 0.028 13.7 0.0 0.062 12.6 0.0 1.7 1 0 0 1 1 1 0 Septin TsaE PF02367.17 KNZ73064.1 - 0.032 14.3 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FeoB_N PF02421.18 KNZ73064.1 - 0.084 12.4 0.2 5.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF2258 PF10015.9 KNZ73064.1 - 0.11 12.6 0.2 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) SAM_2 PF07647.17 KNZ73065.1 - 4.1e-10 39.6 0.0 2.1e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KNZ73065.1 - 0.00023 21.5 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1281 PF06924.11 KNZ73065.1 - 0.013 15.1 0.1 0.022 14.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF4508 PF14969.6 KNZ73065.1 - 0.038 14.3 0.1 0.078 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) adh_short PF00106.25 KNZ73066.1 - 3.1e-43 147.5 0.6 3.8e-43 147.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ73066.1 - 5.2e-34 117.8 0.2 6.5e-34 117.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ73066.1 - 6.4e-07 29.5 0.2 1e-06 28.8 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF3012 PF11216.8 KNZ73066.1 - 0.0094 16.0 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3012) NifU PF01106.17 KNZ73067.1 - 0.00053 20.1 0.0 5.9 7.1 0.0 3.4 3 0 0 3 3 3 2 NifU-like domain BPA_C PF18040.1 KNZ73067.1 - 0.015 15.2 0.2 4.8 7.2 0.0 2.7 3 0 0 3 3 3 0 beta porphyranase A C-terminal DUF4406 PF14359.6 KNZ73067.1 - 0.034 14.6 0.0 11 6.6 0.0 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4406) DEC-1_N PF04625.13 KNZ73067.1 - 2 7.4 7.5 3.3 6.6 7.5 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ADH_zinc_N PF00107.26 KNZ73068.1 - 1e-24 87.0 0.0 1.6e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ73068.1 - 4.8e-18 66.5 0.0 8.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ73068.1 - 2.7e-06 27.2 0.0 1.7e-05 24.6 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Peptidase_S9 PF00326.21 KNZ73069.1 - 3.3e-05 23.5 0.3 0.00011 21.7 0.3 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KNZ73069.1 - 9.5e-05 21.8 0.1 0.00051 19.4 0.1 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ73069.1 - 0.0022 18.7 1.0 0.0035 18.0 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 KNZ73069.1 - 0.0053 16.1 0.0 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1749 PF08538.10 KNZ73069.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Ribosomal_L1 PF00687.21 KNZ73070.1 - 1.2e-57 194.9 0.8 1.9e-57 194.3 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MRC1 PF09444.10 KNZ73070.1 - 9.3 6.7 8.3 0.96 9.9 1.8 2.3 3 0 0 3 3 3 0 MRC1-like domain Peptidase_M64 PF09471.10 KNZ73072.1 - 2.4e-28 99.4 0.0 2.2e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 IgA Peptidase M64 HD-ZIP_N PF04618.12 KNZ73072.1 - 0.015 15.8 0.1 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 HD-ZIP protein N terminus MIP PF00230.20 KNZ73074.1 - 2.6e-52 177.8 8.2 3.1e-52 177.5 8.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein EamA PF00892.20 KNZ73074.1 - 0.025 14.8 1.1 0.025 14.8 1.1 2.7 3 0 0 3 3 3 0 EamA-like transporter family Oxidored_q3 PF00499.20 KNZ73074.1 - 0.056 13.2 0.1 0.056 13.2 0.1 2.4 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 TTc_toxin_rep PF18807.1 KNZ73075.1 - 0.062 13.1 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Tripartite Tc toxins repeat NTR2 PF15458.6 KNZ73075.1 - 0.22 11.0 3.5 3 7.3 3.5 2.5 1 1 0 1 1 1 0 Nineteen complex-related protein 2 Rad60-SLD PF11976.8 KNZ73076.1 - 1.6e-10 40.6 0.4 0.00053 19.8 0.4 3.6 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KNZ73076.1 - 0.0044 16.7 0.0 2.3 8.0 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin family GEN1_C PF18380.1 KNZ73076.1 - 9 7.2 9.6 0.99 10.3 0.1 3.3 3 1 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain mRNA_triPase PF02940.15 KNZ73077.1 - 2.1e-53 181.3 0.0 2.5e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Porin_3 PF01459.22 KNZ73078.1 - 1.1e-69 234.9 3.5 1.2e-69 234.8 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.25 KNZ73079.1 - 2.2e-42 145.2 0.0 6.4e-42 143.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73079.1 - 1.1e-23 83.8 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ73079.1 - 0.0002 21.4 0.0 0.00055 19.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ73079.1 - 0.00041 19.8 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ73079.1 - 0.0046 15.8 3.6 0.015 14.1 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 KNZ73079.1 - 0.2 11.2 0.3 0.72 9.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ73080.1 - 8.7e-75 251.5 0.0 1.6e-74 250.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73080.1 - 2e-52 178.1 0.0 3.5e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ73080.1 - 0.0016 17.3 0.0 0.0025 16.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 KNZ73080.1 - 0.0025 17.8 1.0 26 5.1 0.0 6.0 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 KNZ73080.1 - 0.0042 16.4 0.0 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF4704 PF15787.5 KNZ73080.1 - 0.074 12.3 3.1 1 8.5 0.2 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4704) RICTOR_N PF14664.6 KNZ73080.1 - 0.079 11.9 8.9 0.75 8.7 0.3 2.8 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term FTA2 PF13095.6 KNZ73080.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Adaptin_N PF01602.20 KNZ73080.1 - 0.2 10.2 2.8 2.4 6.6 0.1 3.0 2 1 0 3 3 3 0 Adaptin N terminal region CBF PF03914.17 KNZ73080.1 - 1.2 9.2 3.1 20 5.1 0.2 3.0 3 0 0 3 3 3 0 CBF/Mak21 family RVT_1 PF00078.27 KNZ73081.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KNZ73082.1 - 6.3e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 RNase H WD40 PF00400.32 KNZ73084.1 - 3.2e-11 43.6 1.6 0.035 15.0 0.0 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ73084.1 - 1.5e-07 31.6 0.0 0.011 16.0 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Homeodomain PF00046.29 KNZ73085.1 - 0.0065 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain SPESP1 PF15754.5 KNZ73086.1 - 2.7 7.1 6.0 3.9 6.6 6.0 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Mob1_phocein PF03637.17 KNZ73087.1 - 2.3e-66 223.0 1.3 2.8e-66 222.7 1.3 1.0 1 0 0 1 1 1 1 Mob1/phocein family RhoGEF PF00621.20 KNZ73088.1 - 7e-09 36.2 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Mannosyl_trans2 PF04188.13 KNZ73090.1 - 1.9e-29 103.3 10.0 5.1e-23 82.1 8.1 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) Rhodanese PF00581.20 KNZ73091.1 - 1e-06 29.2 0.0 2.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 KNZ73091.1 - 0.002 18.9 0.0 0.19 12.6 0.0 3.1 2 0 0 2 2 2 1 WD domain, G-beta repeat PH PF00169.29 KNZ73092.1 - 0.019 15.5 0.1 0.05 14.1 0.1 1.7 1 0 0 1 1 1 0 PH domain POB3_N PF17292.2 KNZ73093.1 - 1.3e-31 108.9 0.3 2.2e-27 95.3 0.1 2.7 2 0 0 2 2 2 2 POB3-like N-terminal PH domain SSrecog PF03531.14 KNZ73093.1 - 2.3e-28 97.9 0.0 1.3e-27 95.5 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 KNZ73093.1 - 9.6e-21 74.0 0.1 6e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CH PF00307.31 KNZ73094.1 - 4e-44 149.3 0.1 3.7e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KNZ73094.1 - 2.4e-19 69.2 0.1 1.8e-18 66.4 0.0 2.5 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KNZ73094.1 - 1.6e-10 40.7 0.1 1.2e-07 31.5 0.1 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Baculo_PEP_C PF04513.12 KNZ73094.1 - 3.4e-05 23.9 1.5 0.00014 21.9 1.5 2.0 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 KNZ73094.1 - 0.00018 21.9 2.0 0.094 13.2 1.3 2.8 2 0 0 2 2 2 1 Spectrin repeat EF-hand_6 PF13405.6 KNZ73094.1 - 0.00048 19.8 0.0 0.0058 16.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain DUF3584 PF12128.8 KNZ73094.1 - 0.0006 17.5 2.1 0.0011 16.6 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3153 PF11353.8 KNZ73094.1 - 0.0019 17.8 1.4 0.004 16.8 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) Seryl_tRNA_N PF02403.22 KNZ73094.1 - 0.0035 17.5 0.7 0.0076 16.5 0.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain EF-hand_14 PF17959.1 KNZ73094.1 - 0.0093 16.3 0.4 0.83 10.0 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KNZ73094.1 - 0.01 15.3 0.0 0.036 13.6 0.0 2.1 1 0 0 1 1 1 0 EF hand Fib_alpha PF08702.10 KNZ73094.1 - 0.019 15.1 1.5 1.7 8.8 0.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Elongin_A PF06881.11 KNZ73094.1 - 0.041 14.4 1.4 0.28 11.7 0.4 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CENP-K PF11802.8 KNZ73094.1 - 0.053 13.1 0.3 0.097 12.2 0.3 1.4 1 0 0 1 1 1 0 Centromere-associated protein K SF-assemblin PF06705.11 KNZ73094.1 - 0.06 12.7 4.7 0.046 13.1 2.7 1.7 2 0 0 2 2 2 0 SF-assemblin/beta giardin Spc7 PF08317.11 KNZ73094.1 - 0.062 12.2 4.5 0.075 11.9 3.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4456 PF14644.6 KNZ73094.1 - 0.092 12.4 1.9 0.16 11.7 0.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4456) NPV_P10 PF05531.12 KNZ73094.1 - 0.095 13.2 0.6 0.74 10.3 0.7 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EF-hand_7 PF13499.6 KNZ73094.1 - 0.12 12.8 0.3 0.66 10.5 0.1 2.4 2 1 0 2 2 1 0 EF-hand domain pair Exonuc_VII_L PF02601.15 KNZ73094.1 - 0.14 11.7 4.2 0.2 11.2 4.2 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF3138 PF11336.8 KNZ73094.1 - 0.21 10.2 0.8 0.35 9.4 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Helo_like_N PF17111.5 KNZ73094.1 - 0.38 10.1 3.8 0.4 10.0 0.5 2.4 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins Uso1_p115_C PF04871.13 KNZ73094.1 - 0.46 10.9 2.9 39 4.6 0.0 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cofilin_ADF PF00241.20 KNZ73095.1 - 8.1e-42 141.9 0.4 9e-42 141.7 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein gag-asp_proteas PF13975.6 KNZ73096.1 - 0.00088 19.8 0.0 0.0012 19.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ73096.1 - 0.0026 18.4 0.0 0.0048 17.5 0.0 1.5 1 1 0 1 1 1 1 Aspartyl protease DUF5425 PF17472.2 KNZ73097.1 - 0.055 14.2 0.1 0.064 14.0 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5425) DUF3605 PF12239.8 KNZ73098.1 - 7.2e-28 97.8 0.1 4.4e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) LRR_6 PF13516.6 KNZ73100.1 - 8.5e-08 31.7 18.2 0.36 11.0 0.0 7.3 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KNZ73100.1 - 0.016 15.6 20.6 5.5 7.6 0.2 6.1 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ73100.1 - 0.086 12.6 16.0 21 5.0 5.6 5.6 4 2 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KNZ73100.1 - 0.14 12.8 14.2 13 6.8 0.2 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat TPR_MLP1_2 PF07926.12 KNZ73101.1 - 2.9e-27 95.3 20.5 2.9e-27 95.3 20.5 17.6 7 5 9 17 17 17 6 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 KNZ73101.1 - 0.0023 17.9 3.5 0.0023 17.9 3.5 18.7 8 3 10 21 21 21 2 BRE1 E3 ubiquitin ligase DUF2321 PF10083.9 KNZ73101.1 - 2.1 7.9 4.5 2.6 7.6 0.8 3.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Hemerythrin PF01814.23 KNZ73103.1 - 2.3e-12 47.6 0.2 4.1e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Chromo PF00385.24 KNZ73104.1 - 4e-06 26.6 0.5 6.2e-06 26.0 0.5 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SWIRM-assoc_2 PF16496.5 KNZ73104.1 - 0.0045 15.9 0.4 0.0048 15.8 0.4 1.1 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Pkinase PF00069.25 KNZ73105.1 - 8.3e-38 130.3 0.0 6.8e-16 58.4 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73105.1 - 1e-12 47.9 0.3 0.0004 19.7 0.1 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KNZ73105.1 - 0.097 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Lipase_GDSL_2 PF13472.6 KNZ73106.1 - 3.7e-06 27.5 0.0 5.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KNZ73106.1 - 2.5e-05 24.3 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aldo_ket_red PF00248.21 KNZ73107.1 - 7.2e-68 228.9 0.0 8.6e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KNZ73108.1 - 1.8e-54 185.1 0.0 2.5e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ73108.1 - 1.2e-36 126.4 0.0 1.8e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KNZ73108.1 - 4.4e-07 29.8 0.2 0.0039 16.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ73108.1 - 5.1e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KNZ73108.1 - 7.9e-05 22.0 0.0 0.00045 19.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ73108.1 - 9.1e-05 21.7 0.1 0.013 14.6 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KNZ73108.1 - 0.0002 20.6 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KNZ73108.1 - 0.0039 16.5 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 KNZ73108.1 - 0.057 12.1 0.0 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KNZ73108.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GDI PF00996.18 KNZ73108.1 - 0.21 10.1 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor AMP-binding PF00501.28 KNZ73109.1 - 3e-79 266.6 0.0 4.1e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ73109.1 - 0.042 14.8 1.0 0.19 12.7 0.2 2.5 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain Glyco_hydro_61 PF03443.14 KNZ73110.1 - 1.1e-39 136.5 0.0 1.4e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MG2 PF01835.19 KNZ73110.1 - 0.068 13.6 0.0 0.091 13.2 0.0 1.2 1 0 0 1 1 1 0 MG2 domain YhdB PF14148.6 KNZ73112.1 - 0.09 12.9 0.1 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 YhdB-like protein Abhydrolase_1 PF00561.20 KNZ73113.1 - 1e-09 38.4 0.0 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ73113.1 - 3.5e-09 37.6 0.1 6.2e-09 36.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ73113.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KNZ73113.1 - 0.086 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 KNZ73113.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CMD PF02627.20 KNZ73113.1 - 0.14 12.2 0.1 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Erythro-docking PF09277.11 KNZ73113.1 - 0.17 11.8 0.3 8 6.5 0.1 2.3 2 0 0 2 2 2 0 Erythronolide synthase, docking gag-asp_proteas PF13975.6 KNZ73114.1 - 0.0051 17.3 0.0 0.011 16.3 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ73114.1 - 0.013 16.1 0.0 0.029 15.0 0.0 1.6 2 0 0 2 2 2 0 Aspartyl protease Aldo_ket_red PF00248.21 KNZ73116.1 - 3e-70 236.7 0.0 4e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cep57_CLD PF14073.6 KNZ73118.1 - 0.012 15.6 8.1 0.8 9.7 0.3 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 TolA_bind_tri PF16331.5 KNZ73118.1 - 0.013 15.6 0.8 0.013 15.6 0.8 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation H_kinase_N PF12282.8 KNZ73118.1 - 0.044 13.7 0.2 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 Signal transduction histidine kinase Tropomyosin_1 PF12718.7 KNZ73118.1 - 0.16 12.1 5.2 1.6 8.9 0.4 2.7 2 0 0 2 2 2 0 Tropomyosin like FlaC_arch PF05377.11 KNZ73118.1 - 0.25 11.7 2.5 12 6.4 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 KNZ73118.1 - 0.26 11.4 7.2 0.37 10.9 0.3 2.8 3 0 0 3 3 3 0 bZIP transcription factor P4Ha_N PF08336.11 KNZ73118.1 - 0.83 9.7 3.6 7.3 6.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region zf-CCHC PF00098.23 KNZ73118.1 - 1.3 9.2 5.2 2.2 8.5 5.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Fib_alpha PF08702.10 KNZ73118.1 - 1.3 9.2 3.9 15 5.7 0.1 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 KNZ73118.1 - 2.8 8.1 7.7 11 6.2 1.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper DUF5082 PF16888.5 KNZ73118.1 - 3.6 7.9 7.4 1.1 9.6 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 KNZ73118.1 - 5.2 7.1 10.2 5.6 7.0 0.5 3.0 3 0 0 3 3 3 0 Prefoldin subunit Pkinase_fungal PF17667.1 KNZ73119.1 - 5.6e-62 209.8 0.2 8e-62 209.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KNZ73119.1 - 0.00092 18.7 0.7 0.004 16.6 0.2 2.3 3 0 0 3 3 3 1 Protein kinase domain FliJ PF02050.16 KNZ73119.1 - 0.019 15.2 1.6 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein TAtT PF16811.5 KNZ73119.1 - 0.042 13.1 0.4 0.076 12.3 0.4 1.3 1 0 0 1 1 1 0 TRAP transporter T-component MF_alpha_N PF05436.11 KNZ73120.1 - 0.46 10.4 2.0 0.77 9.7 0.5 2.1 2 1 0 2 2 2 0 Mating factor alpha precursor N-terminus DUF4939 PF16297.5 KNZ73123.1 - 0.00055 19.8 0.0 0.00074 19.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) DUF2576 PF10845.8 KNZ73126.1 - 0.15 11.7 0.5 0.39 10.4 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Ank_2 PF12796.7 KNZ73127.1 - 8e-16 58.4 0.5 1.9e-15 57.2 0.4 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ73127.1 - 5.2e-09 36.5 0.2 0.00023 21.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ73127.1 - 2.8e-07 30.3 0.4 0.055 14.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KNZ73127.1 - 9.3e-07 29.0 5.7 0.0042 17.5 0.1 3.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KNZ73127.1 - 5.5e-06 26.6 0.4 0.063 13.6 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Phage_r1t_holin PF16945.5 KNZ73128.1 - 0.0062 16.7 0.4 0.016 15.4 0.2 1.7 2 0 0 2 2 2 1 Putative lactococcus lactis phage r1t holin SCHIP-1 PF10148.9 KNZ73129.1 - 0.086 12.4 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 UPF0147 PF03685.13 KNZ73130.1 - 0.035 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Bac_export_1 PF01311.20 KNZ73132.1 - 0.3 10.6 1.2 0.57 9.7 1.2 1.4 1 0 0 1 1 1 0 Bacterial export proteins, family 1 RVP_2 PF08284.11 KNZ73134.1 - 0.066 13.0 0.1 6.2 6.6 0.0 2.5 2 1 0 2 2 2 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 KNZ73135.1 - 0.012 15.7 0.6 0.024 14.8 0.6 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain RVT_1 PF00078.27 KNZ73135.1 - 0.039 13.5 0.2 0.065 12.7 0.2 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TIR-like PF10137.9 KNZ73135.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF443 PF04276.12 KNZ73135.1 - 0.75 9.6 5.0 0.18 11.6 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF443) RNase_H PF00075.24 KNZ73136.1 - 0.0018 18.5 1.9 0.0031 17.7 1.9 1.5 1 1 0 1 1 1 1 RNase H rve PF00665.26 KNZ73140.1 - 3.5e-13 49.8 0.0 4.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain TUG-UBL1 PF11470.8 KNZ73140.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 TUG ubiquitin-like domain rve_3 PF13683.6 KNZ73140.1 - 0.013 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Helo_like_N PF17111.5 KNZ73140.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins CN_hydrolase PF00795.22 KNZ73145.1 - 5.6e-12 45.6 0.0 8e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4632 PF15451.6 KNZ73145.1 - 0.019 15.0 2.7 0.058 13.5 2.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Helicase_C PF00271.31 KNZ73146.1 - 2.9e-17 63.0 0.0 3.3e-15 56.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KNZ73146.1 - 2.2e-09 37.9 1.3 3.9e-09 37.1 0.5 1.9 2 0 0 2 2 2 1 RecQ zinc-binding DEAD PF00270.29 KNZ73146.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Aldolase_II PF00596.21 KNZ73147.1 - 8.1e-38 130.2 0.0 9.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Melibiase_2 PF16499.5 KNZ73148.1 - 3.5e-48 164.2 3.0 5.6e-29 101.2 0.6 2.4 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KNZ73148.1 - 8.2e-13 48.2 1.8 1.2e-12 47.7 0.8 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KNZ73148.1 - 0.00037 19.5 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Melibiase Nepo_coat PF03391.15 KNZ73148.1 - 1.7 8.1 5.8 0.29 10.6 1.9 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, central domain PAS_3 PF08447.12 KNZ73149.1 - 9.4e-09 35.4 0.0 3.3e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 KNZ73149.1 - 0.00038 20.4 0.0 0.0078 16.2 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 KNZ73149.1 - 0.012 15.7 0.0 0.039 14.1 0.0 1.8 2 0 0 2 2 2 0 PAS domain PAS_9 PF13426.7 KNZ73149.1 - 0.13 12.6 0.0 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 PAS domain GCD14 PF08704.10 KNZ73150.1 - 9.7e-85 284.2 1.8 8.4e-83 277.8 1.8 2.8 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KNZ73150.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 KNZ73150.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_24 PF13578.6 KNZ73150.1 - 0.015 16.3 0.0 0.03 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73150.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Stathmin PF00836.19 KNZ73150.1 - 0.045 13.7 2.8 0.078 13.0 2.8 1.3 1 0 0 1 1 1 0 Stathmin family Fibrillarin PF01269.17 KNZ73150.1 - 0.15 11.2 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Fibrillarin DUF3847 PF12958.7 KNZ73150.1 - 0.45 10.7 3.2 1.4 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) BHD_3 PF10405.9 KNZ73151.1 - 1.1e-27 96.3 0.4 2.1e-27 95.3 0.4 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 KNZ73151.1 - 2.7e-23 82.3 0.4 2.6e-22 79.1 0.0 2.5 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 KNZ73151.1 - 5.8e-20 70.9 0.0 1.4e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KNZ73151.1 - 4e-16 59.7 0.4 4e-16 59.7 0.4 2.8 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 KNZ73151.1 - 4.1e-08 33.7 0.0 1.8e-07 31.6 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily SWIRM-assoc_2 PF16496.5 KNZ73151.1 - 0.87 8.4 6.1 1.8 7.3 6.1 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal zf-RVT PF13966.6 KNZ73152.1 - 0.015 16.0 1.9 0.017 15.8 1.9 1.1 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Sdh_cyt PF01127.22 KNZ73152.1 - 0.028 14.4 0.0 0.03 14.4 0.0 1.1 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RT_RNaseH PF17917.1 KNZ73153.1 - 0.0027 18.0 0.0 0.0038 17.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KNZ73154.1 - 0.0043 17.1 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain MFS_1 PF07690.16 KNZ73155.1 - 4.7e-25 88.3 40.7 1.1e-14 54.2 9.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ73155.1 - 3.5e-21 75.6 20.8 1.9e-19 69.9 0.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter CEND1 PF15677.5 KNZ73155.1 - 0.18 12.4 8.0 0.33 11.5 8.0 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 Ribonuc_L-PSP PF01042.21 KNZ73156.1 - 2e-06 27.8 0.2 0.0067 16.4 0.0 2.1 1 1 1 2 2 2 2 Endoribonuclease L-PSP BNR_4 PF15892.5 KNZ73157.1 - 6.7e-36 124.0 1.8 8.5e-26 90.9 1.3 2.2 1 1 1 2 2 2 2 BNR repeat-containing family member BNR PF02012.20 KNZ73157.1 - 0.016 15.1 1.4 0.11 12.6 0.6 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat APH PF01636.23 KNZ73159.1 - 1.2e-14 54.9 0.0 7.1e-14 52.3 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KNZ73159.1 - 3.5e-05 22.9 0.1 0.0032 16.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.14 KNZ73159.1 - 0.021 14.2 0.0 0.062 12.6 0.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Avl9 PF09794.9 KNZ73160.1 - 7.1e-122 406.8 0.0 9.3e-122 406.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 KNZ73160.1 - 3.1e-08 33.6 0.1 0.00092 18.9 0.1 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KNZ73160.1 - 2.4e-06 27.5 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2235 PF09994.9 KNZ73162.1 - 3.4e-88 295.7 0.0 6.3e-88 294.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KNZ73162.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pkinase PF00069.25 KNZ73163.1 - 1.5e-66 224.5 0.0 1.8e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73163.1 - 8.5e-36 123.6 0.0 1.1e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KNZ73163.1 - 0.0029 16.7 0.0 0.0071 15.4 0.1 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 KNZ73163.1 - 0.01 15.2 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 KNZ73163.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KNZ73163.1 - 0.13 11.8 0.0 0.35 10.4 0.0 1.6 1 1 1 2 2 2 0 RIO1 family RabGAP-TBC PF00566.18 KNZ73164.1 - 5.7e-31 107.8 0.0 7.9e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_2 PF07653.17 KNZ73164.1 - 0.0007 19.2 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ73164.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Cwf_Cwc_15 PF04889.12 KNZ73164.1 - 0.57 9.9 5.5 1.2 8.8 5.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-MYND PF01753.18 KNZ73165.1 - 3.4e-10 39.9 4.4 9.5e-10 38.4 4.4 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 KNZ73165.1 - 0.0026 17.8 1.3 0.0065 16.5 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YjeF_N PF03853.15 KNZ73166.1 - 1e-32 113.4 0.0 1.4e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FYRN PF05964.14 KNZ73168.1 - 9.2e-18 63.8 0.6 2e-17 62.8 0.6 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 KNZ73168.1 - 1.7e-15 56.9 0.0 3.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus cIII PF08134.11 KNZ73168.1 - 0.18 11.6 0.5 0.43 10.4 0.5 1.6 1 0 0 1 1 1 0 cIII protein family Abhydrolase_3 PF07859.13 KNZ73169.1 - 1.6e-17 64.1 0.6 2.3e-12 47.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ73169.1 - 3e-12 46.5 0.1 2.8e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KNZ73169.1 - 0.00062 19.1 0.1 0.058 12.7 0.0 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 KNZ73169.1 - 0.0012 18.5 0.1 0.91 9.0 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KNZ73169.1 - 0.0017 18.2 0.4 0.027 14.3 0.0 2.5 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase COesterase PF00135.28 KNZ73169.1 - 0.015 14.2 0.1 4.3 6.1 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_6 PF12697.7 KNZ73169.1 - 0.017 15.7 13.8 0.069 13.8 13.8 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KNZ73169.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein LIP PF03583.14 KNZ73169.1 - 0.1 11.9 0.1 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase CsbD PF05532.12 KNZ73171.1 - 0.17 11.8 1.8 0.19 11.7 0.6 1.7 2 0 0 2 2 2 0 CsbD-like SIR2 PF02146.17 KNZ73172.1 - 2.7e-40 138.2 0.0 9.1e-36 123.4 0.0 2.3 1 1 1 2 2 2 2 Sir2 family p450 PF00067.22 KNZ73173.1 - 9.3e-74 248.8 0.0 1.1e-73 248.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0147 PF03685.13 KNZ73174.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) p450 PF00067.22 KNZ73175.1 - 3.2e-72 243.8 0.0 3.9e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.32 KNZ73176.1 - 6.7e-25 86.9 3.2 0.00016 22.4 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ73176.1 - 2.1e-10 40.7 0.2 0.085 13.2 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ73176.1 - 0.0008 18.2 0.6 0.027 13.1 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ73176.1 - 0.0058 15.6 0.7 2.6 6.9 0.1 3.1 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KNZ73176.1 - 0.015 14.9 0.1 0.045 13.3 0.1 1.9 1 1 0 1 1 1 0 PQQ-like domain WD40_like PF17005.5 KNZ73176.1 - 0.027 13.8 0.2 2.2 7.5 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain Gmad1 PF10647.9 KNZ73176.1 - 0.036 13.8 0.3 0.47 10.2 0.3 2.4 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Antig_Caf1 PF09255.10 KNZ73177.1 - 0.017 15.3 1.1 0.83 9.8 0.5 2.2 2 0 0 2 2 2 0 Caf1 Capsule antigen BTB PF00651.31 KNZ73178.1 - 0.021 15.1 0.0 0.055 13.7 0.0 1.8 2 1 0 2 2 2 0 BTB/POZ domain Peptidase_S28 PF05577.12 KNZ73179.1 - 4.5e-55 187.2 0.0 9.3e-55 186.1 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Chromo PF00385.24 KNZ73180.1 - 4.7e-17 61.6 0.0 6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.8 KNZ73180.1 - 0.0082 16.0 0.4 0.0082 16.0 0.4 1.9 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain Mtf2_C PF14061.6 KNZ73180.1 - 0.05 13.8 0.1 0.071 13.3 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Zn_clus PF00172.18 KNZ73181.1 - 0.17 12.1 5.7 3.6 7.8 0.6 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.12 KNZ73184.1 - 0.44 11.1 1.0 1 9.8 1.0 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein A_deaminase PF00962.22 KNZ73185.1 - 4.5e-121 404.2 0.2 6.8e-121 403.6 0.2 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Methyltransf_2 PF00891.18 KNZ73186.1 - 1.8e-17 63.4 0.0 3.4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KNZ73186.1 - 0.00042 20.3 0.3 0.0014 18.6 0.1 2.1 2 0 0 2 2 2 1 Dimerisation domain Dimerisation2 PF16864.5 KNZ73186.1 - 0.0062 16.5 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain DUF3292 PF11696.8 KNZ73186.1 - 0.14 10.5 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) UQ_con PF00179.26 KNZ73187.1 - 4.9e-10 39.2 0.0 9.5e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ebp2 PF05890.12 KNZ73188.1 - 1.5e-88 296.8 7.8 1.5e-88 296.8 7.8 1.6 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Asp PF00026.23 KNZ73189.1 - 1.6e-38 132.9 0.1 2.1e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ73189.1 - 0.0016 18.7 0.3 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal WD40 PF00400.32 KNZ73190.1 - 2.6e-07 31.2 7.4 0.00069 20.4 0.1 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat HCV_NS1 PF01560.17 KNZ73190.1 - 0.057 12.1 0.1 5.1 5.7 0.0 2.2 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein E2/NS1 Q_salvage PF10343.9 KNZ73191.1 - 6.8e-95 317.9 0.0 9.8e-95 317.3 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Ribonuc_red_lgC PF02867.15 KNZ73193.1 - 3.9e-180 599.9 0.0 5.1e-180 599.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 KNZ73193.1 - 1.4e-24 85.8 0.0 4.2e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 KNZ73193.1 - 2.4e-13 50.4 0.2 2e-12 47.5 0.1 2.4 2 0 0 2 2 2 1 ATP cone domain Dor1 PF04124.12 KNZ73194.1 - 0.021 13.5 1.4 0.054 12.2 1.7 1.5 1 1 1 2 2 2 0 Dor1-like family COX6B PF02297.17 KNZ73194.1 - 0.12 12.7 0.2 0.25 11.6 0.2 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb GPHR_N PF12537.8 KNZ73196.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal F-box-like PF12937.7 KNZ73197.1 - 0.0079 16.1 2.8 0.027 14.4 2.8 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ73197.1 - 3.9 7.5 5.8 5 7.1 0.9 3.2 3 0 0 3 3 3 0 F-box domain Methyltransf_33 PF10017.9 KNZ73198.1 - 2.4e-71 240.4 0.0 3.1e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KNZ73198.1 - 2.5e-22 79.7 0.1 1.2e-11 44.7 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KNZ73198.1 - 6.3e-05 23.5 1.0 0.00013 22.5 1.0 1.5 1 0 0 1 1 1 1 DinB superfamily DHHC PF01529.20 KNZ73199.1 - 3.5e-36 124.3 2.6 3.5e-36 124.3 2.6 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4064 PF13273.6 KNZ73199.1 - 0.031 14.5 0.8 4.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Ribosomal_L40e PF01020.17 KNZ73199.1 - 0.17 11.8 4.8 0.31 11.0 4.8 1.3 1 0 0 1 1 1 0 Ribosomal L40e family DZR PF12773.7 KNZ73199.1 - 2.1 8.5 8.7 3.6 7.7 8.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon 4HBT_3 PF13622.6 KNZ73200.1 - 2.8e-23 83.5 0.6 3.6e-23 83.1 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2931 PF11153.8 KNZ73200.1 - 0.15 11.8 0.1 0.29 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) 4HBT_3 PF13622.6 KNZ73201.1 - 3.8e-30 106.0 0.1 6.2e-30 105.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KNZ73201.1 - 0.014 15.7 0.1 0.05 14.0 0.1 2.0 1 1 0 1 1 1 0 Thioesterase superfamily Dynactin_p62 PF05502.13 KNZ73202.1 - 1.4e-42 146.1 0.1 3.2e-27 95.5 0.1 2.1 1 1 1 2 2 2 2 Dynactin p62 family ZF-HD_dimer PF04770.12 KNZ73205.1 - 0.18 12.1 0.6 0.62 10.4 0.0 2.0 2 0 0 2 2 2 0 ZF-HD protein dimerisation region DUF680 PF05079.12 KNZ73206.1 - 3.6 8.4 8.8 0.61 10.8 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF680) Asp PF00026.23 KNZ73208.1 - 1.7e-10 40.8 0.0 1.8e-09 37.5 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease COX6C PF02937.15 KNZ73208.1 - 0.17 12.0 0.3 0.37 10.9 0.3 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Asp PF00026.23 KNZ73209.1 - 6.3e-23 81.7 6.1 1.7e-20 73.7 6.1 2.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 KNZ73209.1 - 9.9e-06 26.0 0.3 0.0015 19.0 0.1 2.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ73209.1 - 2e-05 25.1 0.9 0.00031 21.3 0.2 3.0 2 2 0 2 2 2 1 Aspartyl protease DUF2207 PF09972.9 KNZ73209.1 - 0.0093 14.8 0.0 0.018 13.8 0.0 1.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) Orthoreo_P10 PF07204.11 KNZ73209.1 - 0.011 15.7 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TAXi_N PF14543.6 KNZ73209.1 - 0.074 13.3 7.4 0.095 12.9 0.2 2.6 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal Heme_oxygenase PF01126.20 KNZ73210.1 - 2e-41 142.1 0.0 3.4e-41 141.3 0.0 1.4 1 1 0 1 1 1 1 Heme oxygenase Heme_oxygenase PF01126.20 KNZ73211.1 - 8.2e-36 123.7 0.0 1.1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase zf-RING_2 PF13639.6 KNZ73213.1 - 3e-11 43.4 7.1 7.5e-11 42.2 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KNZ73213.1 - 8.3e-10 38.2 6.4 8.3e-10 38.2 6.4 2.2 3 0 0 3 3 3 1 RING-like zinc finger PA PF02225.22 KNZ73213.1 - 8.6e-07 28.9 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 KNZ73213.1 - 2e-06 27.7 5.1 4.4e-06 26.6 5.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KNZ73213.1 - 1.7e-05 24.6 6.7 3.6e-05 23.5 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KNZ73213.1 - 8.7e-05 22.7 8.4 0.00045 20.4 8.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KNZ73213.1 - 0.00045 20.0 6.5 0.0011 18.7 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ73213.1 - 0.0051 16.8 9.4 0.0056 16.7 1.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KNZ73213.1 - 0.019 14.8 5.6 0.062 13.2 5.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KNZ73213.1 - 0.047 13.7 5.0 0.26 11.4 5.0 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 KNZ73213.1 - 0.05 13.5 6.1 0.12 12.3 6.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 KNZ73213.1 - 0.24 11.1 6.2 0.28 10.8 4.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 KNZ73213.1 - 0.48 10.3 3.5 1.2 9.0 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Glyco_hydro_15 PF00723.21 KNZ73214.1 - 7.4e-89 298.6 0.2 9e-89 298.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KNZ73214.1 - 6.8e-24 83.6 0.0 1.7e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Starch binding domain Ysc84 PF04366.12 KNZ73215.1 - 2.9e-45 153.1 0.0 4.8e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 KNZ73216.1 - 1.4e-28 99.2 0.0 2.3e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 KNZ73217.1 - 2.4e-12 46.7 0.0 5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Phosphodiest PF01663.22 KNZ73218.1 - 5.2e-78 263.1 1.0 6.9e-78 262.7 1.0 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KNZ73218.1 - 0.00049 19.6 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 2 Sulfatase RNase_H PF00075.24 KNZ73219.1 - 0.0053 17.0 0.0 0.0085 16.3 0.0 1.4 1 0 0 1 1 1 1 RNase H Pkinase PF00069.25 KNZ73221.1 - 3e-12 46.5 0.0 6.3e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73221.1 - 2.4e-05 23.7 0.0 0.00042 19.7 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KNZ73221.1 - 0.025 14.5 9.6 1.7 8.5 0.4 4.4 4 2 2 6 6 6 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ73221.1 - 0.074 11.8 0.0 2 7.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase RELT PF12606.8 KNZ73221.1 - 0.7 8.9 5.8 2.3 7.3 0.3 2.6 3 0 0 3 3 3 0 Tumour necrosis factor receptor superfamily member 19 VWA_2 PF13519.6 KNZ73222.1 - 0.081 13.6 0.2 0.25 12.0 0.2 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain CagY_I PF14585.6 KNZ73224.1 - 0.0031 17.6 0.8 0.0071 16.4 0.0 2.0 2 0 0 2 2 2 1 CagY type 1 repeat IL3 PF02059.15 KNZ73224.1 - 0.047 13.8 0.3 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Interleukin-3 AAA_5 PF07728.14 KNZ73225.1 - 6.2e-115 379.3 0.0 9.6e-21 74.2 0.0 10.2 9 1 1 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KNZ73225.1 - 4.9e-51 171.4 1.7 2e-18 66.5 0.0 5.6 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 KNZ73225.1 - 2.6e-25 88.5 0.0 6.9e-25 87.2 0.0 1.8 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 KNZ73225.1 - 3.6e-22 78.6 0.0 8e-07 29.0 0.0 7.0 8 0 0 8 8 6 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KNZ73225.1 - 9.2e-21 74.6 0.1 0.00034 21.0 0.0 7.4 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KNZ73225.1 - 1.4e-17 63.8 0.3 0.00078 19.0 0.0 6.0 6 0 0 6 6 5 3 P-loop containing dynein motor region Dynein_heavy PF03028.15 KNZ73225.1 - 6.2e-17 61.8 0.0 0.012 15.7 0.0 5.9 6 0 0 6 6 4 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 KNZ73225.1 - 2.4e-16 60.6 14.8 0.00083 19.8 0.1 8.1 7 2 0 7 7 6 3 AAA ATPase domain Sigma54_activat PF00158.26 KNZ73225.1 - 1.6e-13 50.7 0.0 0.029 14.1 0.0 5.0 4 0 0 4 4 4 4 Sigma-54 interaction domain AAA_6 PF12774.7 KNZ73225.1 - 8.3e-13 48.0 0.0 0.29 10.1 0.0 7.7 8 0 0 8 8 8 3 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 KNZ73225.1 - 7.8e-12 45.9 0.0 1.1 9.8 0.0 6.3 5 0 0 5 5 5 3 AAA domain AAA_22 PF13401.6 KNZ73225.1 - 1.3e-11 44.9 2.1 0.0096 16.2 0.1 6.3 6 0 0 6 6 5 2 AAA domain AAA_14 PF13173.6 KNZ73225.1 - 2.3e-09 37.4 0.0 0.061 13.4 0.0 6.7 7 0 0 7 7 6 2 AAA domain TsaE PF02367.17 KNZ73225.1 - 3.7e-09 36.6 0.2 3.5 7.6 0.0 5.6 5 0 0 5 5 5 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KNZ73225.1 - 1.2e-08 35.1 1.0 0.029 14.5 0.0 5.7 7 0 0 7 7 5 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 KNZ73225.1 - 1.1e-07 31.5 0.1 2.9 7.2 0.0 6.7 7 0 0 7 7 7 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KNZ73225.1 - 1.2e-07 31.1 5.4 0.2 10.7 0.0 6.4 7 0 0 7 7 7 2 Type II/IV secretion system protein ABC_tran PF00005.27 KNZ73225.1 - 2.8e-07 31.1 3.9 0.46 11.0 0.0 5.9 7 0 0 7 7 4 2 ABC transporter AAA_30 PF13604.6 KNZ73225.1 - 3e-07 30.3 0.0 2.1 8.0 0.0 6.6 7 1 0 7 7 5 1 AAA domain RNA_helicase PF00910.22 KNZ73225.1 - 4.8e-06 26.9 0.6 18 5.8 0.0 6.1 7 0 0 7 7 5 0 RNA helicase NACHT PF05729.12 KNZ73225.1 - 4.8e-06 26.6 2.4 1.5 8.7 0.0 5.0 6 0 0 6 6 4 1 NACHT domain AAA_29 PF13555.6 KNZ73225.1 - 1.2e-05 25.0 0.9 4.9 7.0 0.1 5.5 6 0 0 6 6 5 0 P-loop containing region of AAA domain DUF815 PF05673.13 KNZ73225.1 - 5.4e-05 22.5 0.2 6.4 5.9 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 KNZ73225.1 - 9.7e-05 22.2 0.1 2.2 8.0 0.0 4.7 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KNZ73225.1 - 0.0002 21.7 5.7 0.51 10.7 0.1 5.6 5 1 0 5 5 4 1 AAA domain AAA_28 PF13521.6 KNZ73225.1 - 0.0002 21.6 4.7 1.7 8.9 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.6 KNZ73225.1 - 0.00027 21.1 0.3 18 5.5 0.0 5.3 5 0 0 5 5 4 0 AAA domain AAA_25 PF13481.6 KNZ73225.1 - 0.00078 19.1 6.0 5.4 6.5 0.2 5.7 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 KNZ73225.1 - 0.00096 19.1 0.1 15 5.5 0.0 5.0 5 0 0 5 5 5 0 Rad17 P-loop domain AAA_8 PF12780.7 KNZ73225.1 - 0.0014 18.0 0.9 0.63 9.3 0.0 4.7 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 PduV-EutP PF10662.9 KNZ73225.1 - 0.0042 16.8 0.6 2.1 8.1 0.0 4.2 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KNZ73225.1 - 0.0044 16.3 0.0 20 4.4 0.0 4.9 5 0 0 5 5 5 0 Zeta toxin RsgA_GTPase PF03193.16 KNZ73225.1 - 0.006 16.5 0.2 13 5.6 0.0 3.8 3 0 0 3 3 3 0 RsgA GTPase IstB_IS21 PF01695.17 KNZ73225.1 - 0.008 15.9 0.0 16 5.1 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_24 PF13479.6 KNZ73225.1 - 0.0098 15.6 0.0 13 5.4 0.0 4.6 4 0 0 4 4 3 0 AAA domain TniB PF05621.11 KNZ73225.1 - 0.012 15.0 0.0 2.4 7.5 0.0 3.9 4 0 0 4 4 3 0 Bacterial TniB protein Roc PF08477.13 KNZ73225.1 - 0.014 15.6 4.7 3.3 7.9 0.0 4.8 6 0 0 6 6 3 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KNZ73225.1 - 0.017 14.8 0.5 12 5.5 0.0 3.7 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain DEAD PF00270.29 KNZ73225.1 - 0.022 14.5 0.0 2.6 7.8 0.0 3.4 3 0 0 3 3 2 0 DEAD/DEAH box helicase CPT PF07931.12 KNZ73225.1 - 0.024 14.5 1.7 67 3.3 0.0 5.4 6 0 0 6 6 6 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 KNZ73225.1 - 0.024 14.6 0.2 12 5.9 0.0 3.6 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KNZ73225.1 - 0.067 12.5 0.5 5.3 6.3 0.0 3.1 3 0 0 3 3 3 0 KaiC CbiA PF01656.23 KNZ73225.1 - 0.1 12.6 0.4 3 7.9 0.0 3.3 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 KNZ73225.1 - 0.11 12.4 1.9 3.6 7.4 0.0 3.7 4 0 0 4 4 2 0 Deoxynucleoside kinase IPT PF01745.16 KNZ73225.1 - 0.11 11.8 0.1 17 4.7 0.0 3.2 3 0 0 3 3 3 0 Isopentenyl transferase NTPase_1 PF03266.15 KNZ73225.1 - 0.33 10.9 5.4 11 5.9 0.1 4.9 7 0 0 7 7 4 0 NTPase MMR_HSR1 PF01926.23 KNZ73225.1 - 1.3 9.2 2.8 97 3.1 0.0 4.9 6 0 0 6 6 6 0 50S ribosome-binding GTPase DUF2604 PF10790.9 KNZ73225.1 - 2.4 8.5 4.9 24 5.3 0.0 3.8 4 0 0 4 4 3 0 Protein of Unknown function (DUF2604) Pkinase_Tyr PF07714.17 KNZ73227.1 - 6.4e-37 127.2 0.0 7.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ73227.1 - 3.7e-32 111.7 0.0 5.2e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KNZ73227.1 - 4.9e-05 22.3 0.0 7.1e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ73227.1 - 0.017 15.1 0.6 0.031 14.2 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ73227.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Kinase-like KAP PF05804.12 KNZ73227.1 - 0.15 10.2 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Kdo PF06293.14 KNZ73227.1 - 0.18 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Quaking_NLS PF16551.5 KNZ73228.1 - 0.64 9.7 4.9 0.23 11.2 0.8 2.1 1 1 1 2 2 2 0 Putative nuclear localisation signal of quaking Phytase-like PF13449.6 KNZ73229.1 - 1.3e-34 120.4 0.1 1.8e-34 120.0 0.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase mRNA_cap_C PF03919.15 KNZ73230.1 - 0.061 14.0 0.2 0.11 13.1 0.2 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain RGS12_us1 PF16613.5 KNZ73230.1 - 0.11 12.8 0.5 0.21 11.9 0.5 1.4 1 0 0 1 1 1 0 Unstructured region of RGS12 Abhydrolase_1 PF00561.20 KNZ73231.1 - 1.2e-15 57.9 0.0 1.5e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ73231.1 - 9e-15 55.9 0.0 1.1e-14 55.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ73231.1 - 6.5e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KNZ73231.1 - 5e-08 33.4 0.0 7.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KNZ73231.1 - 0.00017 21.4 0.9 0.0029 17.4 0.3 2.7 2 1 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 KNZ73231.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 KNZ73231.1 - 0.0089 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF829 PF05705.14 KNZ73231.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Chlorophyllase PF07224.11 KNZ73231.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 KNZ73231.1 - 0.025 14.5 0.1 0.068 13.0 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 KNZ73231.1 - 0.046 13.4 0.1 0.083 12.5 0.1 1.5 1 1 0 1 1 1 0 Putative esterase Palm_thioest PF02089.15 KNZ73231.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 KNZ73231.1 - 0.091 12.1 0.2 5.5 6.2 0.1 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1057 PF06342.12 KNZ73231.1 - 0.2 10.7 0.3 0.45 9.5 0.0 1.6 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Phytase-like PF13449.6 KNZ73232.1 - 1.6e-33 116.9 0.1 2e-33 116.5 0.1 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase SWI-SNF_Ssr4 PF08549.10 KNZ73233.1 - 1.8e-31 109.6 5.1 1.4e-30 106.7 5.1 1.9 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) CG-1 PF03859.16 KNZ73233.1 - 0.0025 17.6 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 CG-1 domain DivIC PF04977.15 KNZ73233.1 - 1.1 9.0 7.6 6.2 6.7 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 KNZ73233.1 - 4.3 8.0 9.8 3 8.5 2.2 2.7 3 0 0 3 3 3 0 SlyX Pkinase PF00069.25 KNZ73234.1 - 4e-40 137.9 0.0 1.2e-39 136.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73234.1 - 6e-26 91.3 0.0 5.2e-22 78.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ73234.1 - 0.039 12.7 0.0 0.039 12.7 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase CTP_synth_N PF06418.14 KNZ73236.1 - 0.062 12.6 0.0 0.062 12.6 0.0 1.0 1 0 0 1 1 1 0 CTP synthase N-terminus ThylakoidFormat PF11264.8 KNZ73237.1 - 0.021 14.5 0.2 0.029 14.0 0.2 1.1 1 0 0 1 1 1 0 Thylakoid formation protein RVP_2 PF08284.11 KNZ73238.1 - 0.0037 17.0 0.0 0.0048 16.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease PAS_10 PF13596.6 KNZ73241.1 - 0.028 15.0 0.0 0.04 14.5 0.0 1.2 1 0 0 1 1 1 0 PAS domain DUF3398 PF11878.8 KNZ73241.1 - 0.16 12.4 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) RNase_H PF00075.24 KNZ73242.1 - 1.5e-05 25.2 0.1 3.2e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 RNase H 1-cysPrx_C PF10417.9 KNZ73243.1 - 0.0052 16.6 0.2 0.0088 15.9 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box PF00646.33 KNZ73244.1 - 0.00024 20.9 1.8 0.00061 19.6 0.1 2.5 2 0 0 2 2 2 1 F-box domain Sigma70_ner PF04546.13 KNZ73245.1 - 0.012 15.5 4.8 0.02 14.8 4.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region F-box-like PF12937.7 KNZ73245.1 - 0.052 13.5 1.4 0.38 10.7 0.0 3.1 3 1 0 3 3 3 0 F-box-like DUF4611 PF15387.6 KNZ73245.1 - 0.41 10.9 6.1 1 9.6 6.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 KNZ73245.1 - 2.1 7.6 5.8 3.2 7.0 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein FMN_red PF03358.15 KNZ73246.1 - 3.9e-08 33.2 0.0 5.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KNZ73246.1 - 1.1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KNZ73246.1 - 0.0044 17.2 0.0 0.034 14.3 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin Amidase PF01425.21 KNZ73247.1 - 1e-87 295.0 0.0 1.4e-87 294.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Spore_coat_CotO PF14153.6 KNZ73247.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Spore coat protein CotO zf-MYND PF01753.18 KNZ73248.1 - 2.3e-10 40.4 11.2 2.3e-10 40.4 11.2 3.0 2 1 0 2 2 2 1 MYND finger SET PF00856.28 KNZ73248.1 - 7.6e-10 39.4 0.0 1.1e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 SET domain DUF563 PF04577.14 KNZ73249.1 - 7.9e-19 68.6 0.1 2.1e-18 67.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) TFIIA_gamma_N PF02268.16 KNZ73250.1 - 3.6e-25 87.7 0.1 5e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KNZ73250.1 - 2.5e-22 78.7 0.3 4.7e-22 77.9 0.0 1.5 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.14 KNZ73250.1 - 0.035 13.9 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Scytalone dehydratase LRR_4 PF12799.7 KNZ73251.1 - 0.027 14.9 7.9 3.2 8.3 0.0 5.7 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) TBCA PF02970.16 KNZ73251.1 - 0.083 13.2 0.3 0.19 12.1 0.3 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor A TPR_MLP1_2 PF07926.12 KNZ73251.1 - 0.089 12.9 2.2 0.15 12.1 2.2 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Blo-t-5 PF11642.8 KNZ73251.1 - 0.16 12.0 0.1 0.75 9.8 0.0 1.9 2 0 0 2 2 2 0 Mite allergen Blo t 5 F-box-like PF12937.7 KNZ73252.1 - 0.076 12.9 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 KNZ73253.1 - 0.2 11.0 0.0 13 5.0 0.0 2.2 1 1 1 2 2 2 0 Protein kinase domain Amidase PF01425.21 KNZ73254.1 - 1.3e-81 274.9 0.0 2.1e-54 185.2 0.5 2.0 1 1 1 2 2 2 2 Amidase UPF0180 PF03698.13 KNZ73254.1 - 0.079 13.1 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) DUF563 PF04577.14 KNZ73255.1 - 4.5e-21 75.9 0.1 5.8e-21 75.6 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Shikimate_dh_N PF08501.11 KNZ73257.1 - 4.7e-11 42.8 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 KNZ73257.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KNZ73257.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.24 KNZ73258.1 - 1.2e-115 387.0 29.8 1.3e-115 386.8 29.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ73258.1 - 7.4e-20 71.2 49.6 1.3e-19 70.4 42.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.21 KNZ73259.1 - 4e-40 137.7 0.1 4.4e-40 137.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 KNZ73260.1 - 4.2e-46 157.1 0.3 4.6e-46 157.0 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 KNZ73261.1 - 5e-47 160.1 0.6 5.5e-47 160.0 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_M28 PF04389.17 KNZ73262.1 - 1.2e-16 61.0 0.0 1.7e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KNZ73262.1 - 0.0016 18.2 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF2749 PF10907.8 KNZ73262.1 - 0.03 14.5 0.2 0.071 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF4159 PF13709.6 KNZ73263.1 - 0.18 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) RRM_1 PF00076.22 KNZ73264.1 - 1.7e-09 37.4 0.0 5.5e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase_Tyr PF07714.17 KNZ73265.1 - 7.9e-31 107.3 0.0 1.4e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ73265.1 - 3.7e-30 105.2 0.0 7.2e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KNZ73265.1 - 0.041 13.5 1.4 0.94 9.0 0.0 2.9 3 0 0 3 3 3 0 RIO1 family DUF2937 PF11157.8 KNZ73265.1 - 0.058 13.1 1.1 0.29 10.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) APH PF01636.23 KNZ73265.1 - 2.9 7.7 4.7 0.65 9.9 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RNase_H PF00075.24 KNZ73266.1 - 8e-21 74.7 0.3 1.7e-20 73.7 0.1 1.6 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 KNZ73266.1 - 8.8e-05 23.1 1.4 0.00019 22.1 1.4 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase HTH_45 PF14947.6 KNZ73266.1 - 0.039 13.9 0.3 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix Pkinase_Tyr PF07714.17 KNZ73267.1 - 9.4e-44 149.6 0.0 2.3e-23 82.8 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ73267.1 - 1.2e-37 129.8 0.0 7.8e-22 77.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KNZ73267.1 - 0.016 14.6 0.0 0.75 9.1 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Radical_SAM PF04055.21 KNZ73267.1 - 0.022 15.1 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily ABC1 PF03109.16 KNZ73267.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family APH PF01636.23 KNZ73268.1 - 2.2e-12 47.4 0.0 5.6e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Dioxygenase_C PF00775.21 KNZ73269.1 - 2e-49 167.5 0.0 2.7e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KNZ73269.1 - 5.1e-32 109.5 0.0 8.5e-32 108.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KNZ73269.1 - 9.6e-05 22.6 0.0 0.00036 20.7 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Fe-ADH PF00465.19 KNZ73270.1 - 3.2e-74 249.9 5.0 3.6e-74 249.8 5.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KNZ73270.1 - 3.4e-14 53.2 1.2 5.1e-14 52.6 1.2 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AIRC PF00731.20 KNZ73270.1 - 0.023 14.3 0.2 0.063 12.9 0.1 1.8 1 1 0 1 1 1 0 AIR carboxylase Prok-RING_2 PF14445.6 KNZ73270.1 - 0.13 12.5 0.2 0.28 11.4 0.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Oxidored-like PF09791.9 KNZ73272.1 - 7e-18 64.0 0.8 1.3e-17 63.1 0.8 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Bombinin PF05298.11 KNZ73272.1 - 0.062 13.0 0.1 2.3 7.9 0.1 2.1 2 0 0 2 2 2 0 Bombinin MbeB_N PF04837.12 KNZ73272.1 - 0.54 10.6 3.8 1.3 9.4 0.6 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Ribosomal_L18A PF01775.17 KNZ73274.1 - 6.3e-45 152.2 0.8 7.9e-45 151.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Methyltransf_23 PF13489.6 KNZ73275.1 - 1.1e-21 77.4 0.0 1.5e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ73275.1 - 4.8e-20 72.0 0.0 7.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ73275.1 - 8.9e-17 61.6 0.0 1.6e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73275.1 - 5.2e-16 58.8 0.0 6.6e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73275.1 - 2e-15 57.3 0.0 3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KNZ73275.1 - 1.3e-09 37.7 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KNZ73275.1 - 3.2e-07 30.0 0.0 4.8e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KNZ73275.1 - 2e-06 27.3 0.0 2.8e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 KNZ73275.1 - 1.3e-05 24.3 0.0 1.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KNZ73275.1 - 0.00062 19.4 0.0 0.001 18.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KNZ73275.1 - 0.0042 17.1 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KNZ73275.1 - 0.0044 16.7 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.14 KNZ73275.1 - 0.0079 15.6 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 KNZ73275.1 - 0.025 14.2 0.0 0.087 12.5 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 KNZ73275.1 - 0.036 13.6 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 KNZ73275.1 - 0.07 13.1 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DREV PF05219.12 KNZ73275.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase AdoMet_MTase PF07757.13 KNZ73275.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase CSN5_C PF18323.1 KNZ73276.1 - 1.1e-29 103.2 6.4 2.3e-29 102.2 6.4 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain JAB PF01398.21 KNZ73276.1 - 9.2e-29 99.8 0.1 1.9e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KNZ73276.1 - 0.00027 20.7 0.0 0.00059 19.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4404 PF14357.6 KNZ73276.1 - 0.0097 16.5 0.6 0.02 15.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) Vfa1 PF08432.10 KNZ73276.1 - 0.032 14.6 1.4 0.076 13.3 1.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 UPF0172 PF03665.13 KNZ73276.1 - 0.089 12.8 1.1 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Sox_N PF12444.8 KNZ73276.1 - 0.22 12.7 3.2 0.52 11.5 3.2 1.5 1 0 0 1 1 1 0 Sox developmental protein N terminal PseudoU_synth_1 PF01416.20 KNZ73277.1 - 8e-26 90.6 0.0 2.8e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase NPR3 PF03666.13 KNZ73279.1 - 0.026 13.3 2.7 0.027 13.3 2.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 KNZ73279.1 - 0.065 11.4 16.3 0.069 11.4 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 KNZ73279.1 - 0.13 11.5 0.8 0.15 11.3 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 KNZ73279.1 - 0.16 10.9 0.5 0.18 10.7 0.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3682 PF12446.8 KNZ73279.1 - 0.33 11.5 14.4 0.43 11.1 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RP-C_C PF11800.8 KNZ73279.1 - 0.59 10.2 4.7 0.69 10.0 4.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF5523 PF17661.1 KNZ73279.1 - 0.77 9.4 9.5 0.93 9.1 9.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF2201_N PF13203.6 KNZ73279.1 - 0.86 9.1 3.3 1.1 8.8 3.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop25 PF09805.9 KNZ73279.1 - 1.2 9.6 12.4 1.5 9.3 12.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF789 PF05623.12 KNZ73279.1 - 1.9 8.1 5.9 2.2 7.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Presenilin PF01080.17 KNZ73279.1 - 3.6 6.2 6.1 4.3 6.0 6.1 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.8 KNZ73279.1 - 8.2 6.6 18.3 12 6.0 18.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RVP_2 PF08284.11 KNZ73281.1 - 0.031 14.1 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease SGL PF08450.12 KNZ73283.1 - 7.7e-15 55.1 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KNZ73283.1 - 0.012 15.8 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 Arylesterase Str_synth PF03088.16 KNZ73283.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 Strictosidine synthase Cullin PF00888.22 KNZ73286.1 - 6.9e-120 401.5 20.5 9.3e-120 401.1 20.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KNZ73286.1 - 2e-17 62.9 2.1 4.6e-17 61.8 0.6 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Rrf2 PF02082.20 KNZ73286.1 - 0.079 13.3 0.1 0.31 11.4 0.1 2.0 1 0 0 1 1 1 0 Transcriptional regulator Pkinase PF00069.25 KNZ73287.1 - 8.9e-39 133.4 0.0 2.1e-38 132.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73287.1 - 4.2e-38 131.1 0.0 6.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ73287.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NUC130_3NT PF08158.12 KNZ73287.1 - 0.017 15.4 0.3 0.041 14.2 0.3 1.5 1 0 0 1 1 1 0 NUC130/3NT domain PhageP22-tail PF09251.10 KNZ73288.1 - 0.14 10.5 0.0 0.23 9.8 0.0 1.4 1 1 1 2 2 2 0 Salmonella phage P22 tail-spike Pkinase PF00069.25 KNZ73289.1 - 1.7e-34 119.4 0.0 4.3e-34 118.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73289.1 - 1.8e-34 119.2 0.0 2.8e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ73289.1 - 0.005 16.2 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ73289.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KNZ73289.1 - 0.03 13.9 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KNZ73290.1 - 8.5e-42 143.3 0.0 5.2e-41 140.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73290.1 - 1.2e-40 139.5 0.0 2.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ73290.1 - 0.00031 20.1 0.0 0.00073 18.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KNZ73290.1 - 0.00059 19.5 0.0 0.0053 16.4 0.0 2.2 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 KNZ73290.1 - 0.0046 16.3 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNZ73290.1 - 0.017 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KNZ73290.1 - 0.068 13.1 0.0 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family tRNA-synt_1d PF00750.19 KNZ73292.1 - 1.4e-86 290.6 0.9 2.2e-86 290.0 0.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KNZ73292.1 - 5.3e-24 84.7 0.7 1.4e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 DALR anticodon binding domain Peroxin-13_N PF04088.13 KNZ73293.1 - 5.4e-44 150.0 1.3 7.4e-44 149.5 1.3 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 KNZ73293.1 - 5.6e-10 38.7 1.1 0.00089 18.8 1.9 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 KNZ73293.1 - 2.9e-09 36.5 0.0 5.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KNZ73293.1 - 3.7e-08 33.1 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Keratin_2_head PF16208.5 KNZ73293.1 - 3.7 7.7 28.7 6.6 6.9 28.7 1.3 1 0 0 1 1 1 0 Keratin type II head Pkinase_Tyr PF07714.17 KNZ73294.1 - 3.5e-28 98.6 0.0 1.3e-27 96.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ73294.1 - 4.1e-28 98.5 0.0 9.9e-28 97.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.6 KNZ73294.1 - 4.5e-05 22.9 0.0 0.00024 20.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 KNZ73294.1 - 0.0012 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNZ73294.1 - 0.0029 16.4 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KNZ73294.1 - 0.0086 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KNZ73294.1 - 0.02 14.8 0.3 0.08 12.8 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 KNZ73295.1 - 5.6e-06 26.3 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ73295.1 - 1.7e-05 25.0 0.0 3.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TEX13 PF15186.6 KNZ73297.1 - 0.12 12.1 1.0 0.19 11.4 1.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family GMC_oxred_C PF05199.13 KNZ73298.1 - 3.8e-22 79.4 0.0 4.6e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Zn_Tnp_IS1595 PF12760.7 KNZ73299.1 - 6.1e-05 22.9 4.4 6.1e-05 22.9 4.4 1.6 1 1 1 2 2 2 1 Transposase zinc-ribbon domain zf-RVT PF13966.6 KNZ73299.1 - 0.0017 19.0 0.5 0.0025 18.5 0.5 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-FPG_IleRS PF06827.14 KNZ73299.1 - 0.0035 17.1 1.0 0.0068 16.3 1.0 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zinc_ribbon_9 PF14369.6 KNZ73299.1 - 0.12 12.7 0.5 0.12 12.7 0.5 2.3 2 1 0 2 2 2 0 zinc-ribbon PBP_sp32 PF07222.12 KNZ73299.1 - 0.16 11.4 0.4 0.16 11.4 0.4 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Asp_protease_2 PF13650.6 KNZ73301.1 - 0.033 14.8 0.0 0.042 14.5 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease FHA PF00498.26 KNZ73303.1 - 1.4e-16 60.6 0.0 2.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 KNZ73303.1 - 1.7e-06 28.3 0.0 6.9e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Atrophin-1 PF03154.15 KNZ73303.1 - 4.2 5.5 7.2 5.6 5.1 7.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family FMN_dh PF01070.18 KNZ73304.1 - 5.5e-69 232.8 3.9 6.1e-47 160.3 2.3 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 KNZ73304.1 - 8.5e-07 28.3 0.3 3.5e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KNZ73304.1 - 0.0006 19.0 0.1 0.00088 18.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 KNZ73304.1 - 0.022 14.1 0.2 0.3 10.4 0.1 2.1 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG NMO PF03060.15 KNZ73304.1 - 0.042 13.2 0.7 0.065 12.6 0.7 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase COesterase PF00135.28 KNZ73306.1 - 3.7e-88 296.6 0.0 1.5e-86 291.4 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ73306.1 - 6e-05 23.0 0.2 0.0037 17.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ73306.1 - 0.0044 16.5 0.2 0.027 14.0 0.2 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 KNZ73307.1 - 1.9e-81 274.5 0.0 1.6e-77 261.5 0.0 3.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ73307.1 - 1.8e-05 24.7 0.3 0.0036 17.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ73307.1 - 0.013 15.0 0.2 0.029 13.9 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family AAA PF00004.29 KNZ73308.1 - 2.8e-38 131.3 0.0 4.5e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ73308.1 - 2.2e-09 37.0 0.0 5.1e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KNZ73308.1 - 9.4e-07 28.7 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KNZ73308.1 - 4.9e-05 23.8 0.1 0.0015 19.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KNZ73308.1 - 6.8e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KNZ73308.1 - 9.2e-05 22.6 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KNZ73308.1 - 0.00018 21.8 0.1 0.0057 16.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KNZ73308.1 - 0.00018 21.5 0.4 0.0019 18.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KNZ73308.1 - 0.00031 20.7 0.1 0.0013 18.7 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 KNZ73308.1 - 0.00035 21.1 0.0 0.00067 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KNZ73308.1 - 0.00066 19.1 0.2 0.003 17.0 0.2 1.8 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KNZ73308.1 - 0.00075 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KNZ73308.1 - 0.00098 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.6 KNZ73308.1 - 0.0025 18.1 0.0 0.0064 16.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 KNZ73308.1 - 0.0057 15.9 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 KNZ73308.1 - 0.0066 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KNZ73308.1 - 0.007 15.8 0.0 3.1 7.2 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein Sigma54_activ_2 PF14532.6 KNZ73308.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 KNZ73308.1 - 0.014 14.9 0.1 0.073 12.6 0.0 2.2 1 1 1 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KNZ73308.1 - 0.022 14.0 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 KNZ73308.1 - 0.028 14.1 0.1 0.068 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KNZ73308.1 - 0.031 14.2 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 KNZ73308.1 - 0.032 14.7 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ73308.1 - 0.037 13.6 0.2 0.25 10.9 0.2 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KNZ73308.1 - 0.044 14.3 0.0 0.086 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KNZ73308.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KNZ73308.1 - 0.073 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 KNZ73308.1 - 0.074 12.7 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase Hydin_ADK PF17213.3 KNZ73308.1 - 0.095 13.0 0.1 0.81 9.9 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Sigma54_activat PF00158.26 KNZ73308.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 KNZ73308.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2207 PF09972.9 KNZ73308.1 - 0.7 8.6 0.0 0.7 8.6 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Terpene_synth_C PF03936.16 KNZ73309.1 - 2.3e-07 30.4 0.0 8.7e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KNZ73309.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Trehalase PF01204.18 KNZ73310.1 - 1.2e-114 383.9 0.7 4.5e-104 349.1 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.14 KNZ73310.1 - 0.0064 15.5 0.4 0.012 14.5 0.4 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase RRM_1 PF00076.22 KNZ73311.1 - 1.4e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 KNZ73311.1 - 0.0053 17.0 0.2 0.015 15.6 0.2 1.8 1 0 0 1 1 1 1 PWI domain PRP1_N PF06424.12 KNZ73312.1 - 7.4e-50 169.2 4.4 7.4e-50 169.2 4.4 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KNZ73312.1 - 2.5e-22 77.7 42.0 0.0019 18.9 0.8 14.9 7 3 9 16 16 15 7 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ73312.1 - 2e-19 69.9 3.4 0.0028 18.3 0.0 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ73312.1 - 2.2e-13 50.5 13.1 0.07 13.6 0.1 9.7 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73312.1 - 4.4e-09 35.8 4.6 0.41 10.9 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ73312.1 - 0.00012 22.2 6.3 1.7 8.9 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ73312.1 - 0.00033 20.6 4.4 0.33 11.3 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ73312.1 - 0.0017 18.9 5.6 29 5.6 0.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ73312.1 - 0.0017 18.1 0.0 3.4 7.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ73312.1 - 0.049 13.9 10.5 3.9 7.8 0.0 5.7 6 2 0 6 6 5 0 Tetratricopeptide repeat FAT PF02259.23 KNZ73312.1 - 0.05 12.8 9.5 1.2 8.3 5.3 3.9 2 1 0 2 2 2 0 FAT domain Suf PF05843.14 KNZ73312.1 - 0.21 11.5 1.2 46 3.8 0.0 4.4 5 1 0 5 5 5 0 Suppressor of forked protein (Suf) NARP1 PF12569.8 KNZ73312.1 - 0.37 9.6 5.1 5.2 5.9 0.0 4.2 4 1 0 4 4 4 0 NMDA receptor-regulated protein 1 NFACT-R_1 PF05670.13 KNZ73313.1 - 1.7e-39 134.9 0.0 2.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain Methyltransf_25 PF13649.6 KNZ73314.1 - 1.3e-11 45.0 0.1 3.6e-11 43.6 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ73314.1 - 1.9e-10 41.3 0.1 6.6e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KNZ73314.1 - 5e-10 39.3 0.1 8.2e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KNZ73314.1 - 1.4e-08 34.7 0.0 3e-08 33.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ73314.1 - 9.5e-07 28.8 0.0 1.4e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73314.1 - 4.7e-05 24.1 0.0 0.00013 22.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KNZ73314.1 - 5.4e-05 24.2 0.3 0.00016 22.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KNZ73314.1 - 0.00073 19.1 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KNZ73314.1 - 0.044 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.15 KNZ73314.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.14 KNZ73314.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DIOX_N PF14226.6 KNZ73315.1 - 4e-33 114.7 0.0 7.1e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ73315.1 - 4.2e-19 68.9 0.0 7.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HIT PF01230.23 KNZ73316.1 - 1.2e-22 80.5 0.1 1.8e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KNZ73316.1 - 9.9e-11 42.1 0.1 1.7e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KNZ73316.1 - 0.0002 21.2 0.4 0.00034 20.5 0.4 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 p450 PF00067.22 KNZ73317.1 - 2.9e-67 227.4 0.0 3.9e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tn916-Xis PF09035.10 KNZ73317.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Excisionase from transposon Tn916 RPAP1_C PF08620.10 KNZ73318.1 - 1.8e-18 66.4 0.1 4.3e-18 65.2 0.1 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 KNZ73318.1 - 6.9e-09 35.3 1.4 1.5e-08 34.3 1.4 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal GSH_synth_ATP PF03917.17 KNZ73319.1 - 4.7e-128 427.1 0.0 5.5e-128 426.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KNZ73319.1 - 5e-30 104.0 0.4 8.5e-30 103.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase MFS_1 PF07690.16 KNZ73320.1 - 1.6e-26 93.1 26.3 1.6e-26 93.1 26.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Saf_2TM PF18303.1 KNZ73320.1 - 0.7 9.5 0.0 0.7 9.5 0.0 2.8 3 1 0 3 3 3 0 SAVED-fused 2TM effector domain adh_short PF00106.25 KNZ73321.1 - 6.4e-30 104.1 0.4 8e-30 103.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ73321.1 - 1.2e-26 93.7 0.1 1.4e-26 93.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KNZ73321.1 - 0.062 12.7 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) KR PF08659.10 KNZ73321.1 - 0.083 12.8 0.8 0.32 10.9 0.8 1.8 1 1 0 1 1 1 0 KR domain MFS_1 PF07690.16 KNZ73322.1 - 1.9e-28 99.4 22.1 3.1e-28 98.7 22.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LHC PF00556.20 KNZ73322.1 - 0.058 13.6 2.1 3.4 8.0 0.4 3.1 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Phosphoesterase PF04185.14 KNZ73323.1 - 1.3e-30 106.8 1.3 3.9e-30 105.2 1.3 1.7 1 1 0 1 1 1 1 Phosphoesterase family Mad3_BUB1_I PF08311.12 KNZ73323.1 - 0.039 13.9 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TAP_C PF03943.13 KNZ73325.1 - 4.2e-14 51.9 0.0 9.3e-14 50.8 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 KNZ73325.1 - 1.3e-06 28.1 0.7 2.2e-06 27.3 0.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 KNZ73325.1 - 0.00049 20.7 0.0 0.54 10.8 0.0 2.4 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 KNZ73325.1 - 0.00052 19.7 10.7 0.0031 17.3 10.7 2.3 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KNZ73325.1 - 0.00054 20.3 12.8 0.0048 17.3 8.6 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) UBA_4 PF14555.6 KNZ73325.1 - 0.0016 18.2 0.1 0.0073 16.1 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain LRR_1 PF00560.33 KNZ73325.1 - 2.3 9.1 4.2 2.6e+02 2.8 0.0 3.6 2 1 0 2 2 2 0 Leucine Rich Repeat Ank_2 PF12796.7 KNZ73326.1 - 2.3e-20 73.0 0.4 4.8e-08 33.5 0.0 4.9 2 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ73326.1 - 1.8e-17 63.5 8.5 0.00089 19.8 0.0 6.9 5 3 3 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ73326.1 - 7.3e-15 54.8 3.6 0.0002 21.6 0.0 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KNZ73326.1 - 3.5e-11 43.0 11.1 2.3e-05 24.6 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KNZ73326.1 - 4.8e-10 38.8 7.4 0.01 16.3 0.0 6.8 6 0 0 6 6 6 2 Ankyrin repeat Vps39_1 PF10366.9 KNZ73327.1 - 9.3e-29 99.9 0.5 1.7e-27 95.9 0.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KNZ73327.1 - 7e-22 78.0 0.1 1.5e-21 76.9 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 KNZ73327.1 - 3.4e-11 43.2 0.3 6.7e-09 35.8 0.1 2.4 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 KNZ73327.1 - 1.6e-05 24.7 0.0 0.0015 18.2 0.0 3.0 2 1 1 3 3 3 1 CNH domain WD40_like PF17005.5 KNZ73327.1 - 0.031 13.6 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 WD40-like domain PQQ_3 PF13570.6 KNZ73327.1 - 0.058 13.9 0.1 1.7 9.3 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain LAT2 PF15703.5 KNZ73327.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 MFS_1 PF07690.16 KNZ73328.1 - 1.8e-21 76.5 36.9 5.1e-21 75.0 36.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ73328.1 - 3.9e-08 32.6 2.6 3.9e-08 32.6 2.6 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter PIF1 PF05970.14 KNZ73330.1 - 1.8e-15 57.0 0.2 2.6e-15 56.5 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ73330.1 - 1.2e-05 25.7 0.0 2.4e-05 24.8 0.0 1.4 2 0 0 2 2 1 1 AAA ATPase domain ResIII PF04851.15 KNZ73330.1 - 0.00079 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_6 PF12774.7 KNZ73330.1 - 0.0014 17.7 0.0 0.037 13.0 0.0 2.1 1 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 KNZ73330.1 - 0.0015 18.8 0.6 0.02 15.2 0.1 2.2 2 1 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 KNZ73330.1 - 0.003 16.8 0.2 0.0052 16.0 0.2 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 KNZ73330.1 - 0.0037 17.0 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Med29 PF11568.8 KNZ73330.1 - 0.0057 16.9 0.2 0.069 13.4 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 29 AAA_22 PF13401.6 KNZ73330.1 - 0.01 16.1 0.2 0.023 15.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KNZ73330.1 - 0.014 16.0 1.9 0.021 15.3 0.3 1.9 1 1 1 2 2 2 0 ABC transporter DUF2075 PF09848.9 KNZ73330.1 - 0.014 14.6 0.2 0.025 13.8 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zein-binding PF04576.15 KNZ73330.1 - 0.018 15.3 0.5 0.026 14.8 0.5 1.3 1 0 0 1 1 1 0 Zein-binding AAA PF00004.29 KNZ73330.1 - 0.029 14.8 1.8 0.093 13.2 0.2 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KNZ73330.1 - 0.029 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 KNZ73330.1 - 0.035 13.9 0.7 0.054 13.2 0.7 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 KNZ73330.1 - 0.044 12.8 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP_SPB PF02978.19 KNZ73330.1 - 0.048 14.3 0.1 0.081 13.6 0.1 1.3 1 0 0 1 1 1 0 Signal peptide binding domain MitMem_reg PF13012.6 KNZ73330.1 - 0.062 13.7 0.0 0.13 12.7 0.0 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF2791 PF10923.8 KNZ73330.1 - 0.066 12.1 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ATPase PF06745.13 KNZ73330.1 - 0.07 12.5 0.8 1.7 7.9 0.1 2.1 1 1 1 2 2 2 0 KaiC TsaE PF02367.17 KNZ73330.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KNZ73330.1 - 0.075 12.6 0.7 0.29 10.7 0.2 1.9 1 1 2 3 3 3 0 AAA domain Torsin PF06309.11 KNZ73330.1 - 0.088 12.9 0.1 0.33 11.0 0.1 1.9 2 1 0 2 2 2 0 Torsin ATPase_2 PF01637.18 KNZ73330.1 - 0.094 12.6 0.1 0.36 10.7 0.0 1.8 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KNZ73330.1 - 0.12 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 KNZ73330.1 - 0.16 11.3 0.1 0.28 10.4 0.0 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KNZ73330.1 - 0.18 12.3 1.4 0.58 10.7 0.3 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KNZ73330.1 - 0.19 12.0 1.2 0.9 9.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KNZ73330.1 - 0.19 11.4 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Thymidylate_kin PF02223.17 KNZ73330.1 - 0.22 11.2 0.9 4.1 7.0 0.0 2.1 1 1 1 2 2 2 0 Thymidylate kinase ArsA_ATPase PF02374.15 KNZ73330.1 - 1.1 8.4 3.6 1 8.5 0.8 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase DUF4112 PF13430.6 KNZ73331.1 - 0.0077 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Glyco_hydro_17 PF00332.18 KNZ73332.1 - 8.4e-07 28.9 0.0 1.3e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Cellulase PF00150.18 KNZ73334.1 - 3.6e-15 56.2 0.2 3.6e-15 56.2 0.2 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DDE_Tnp_1_2 PF13586.6 KNZ73334.1 - 0.045 14.1 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Pkinase PF00069.25 KNZ73335.1 - 4.8e-32 111.4 0.0 2.1e-16 60.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73335.1 - 4.4e-16 58.9 0.0 1.2e-06 28.0 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 KNZ73335.1 - 0.0026 17.7 0.7 0.065 13.2 0.4 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ73335.1 - 0.061 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ73335.1 - 0.11 11.8 0.0 1.2 8.4 0.0 2.6 4 0 0 4 4 4 0 Kinase-like PIF1 PF05970.14 KNZ73336.1 - 1.1e-29 103.7 0.1 1.4e-29 103.4 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KNZ73336.1 - 2.6e-06 25.7 0.0 3.3e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Helicase 4HPAD_g_N PF18671.1 KNZ73336.1 - 9e-05 22.1 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UvrD_C_2 PF13538.6 KNZ73336.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ73337.1 - 6.8e-13 48.5 0.1 8.2e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.18 KNZ73337.1 - 0.066 12.9 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KNZ73337.1 - 0.13 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.6 KNZ73337.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ73337.1 - 0.22 11.1 0.2 0.28 10.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain TIR PF01582.20 KNZ73338.1 - 0.052 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 TIR domain zf-RVT PF13966.6 KNZ73339.1 - 0.00059 20.5 0.9 0.00089 19.9 0.9 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Glyco_hydro_17 PF00332.18 KNZ73340.1 - 1.1e-06 28.5 0.1 1.2e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF1688 PF07958.11 KNZ73340.1 - 0.16 10.6 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) Peptidase_M56 PF05569.11 KNZ73341.1 - 0.34 10.0 3.8 0.26 10.4 0.3 2.1 2 0 0 2 2 2 0 BlaR1 peptidase M56 Herpes_Helicase PF02689.14 KNZ73343.1 - 1e-05 23.7 0.0 1.1e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ73343.1 - 0.025 14.4 0.1 0.064 13.1 0.1 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Cation_ATPase_C PF00689.21 KNZ73345.1 - 1.1e-39 136.0 7.9 1.1e-39 136.0 7.9 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KNZ73345.1 - 3.4e-32 111.4 0.8 3.4e-32 111.4 0.8 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 KNZ73345.1 - 2.1e-22 79.0 0.0 4.9e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KNZ73345.1 - 6e-12 46.3 0.1 2.2e-10 41.2 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KNZ73345.1 - 4.6e-08 32.6 0.4 5.8e-06 25.9 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF5325 PF17259.2 KNZ73345.1 - 1.9 8.4 7.8 1.4 8.8 1.5 3.6 2 1 0 2 2 2 0 Family of unknown function (DUF5325) CCDC53 PF10152.9 KNZ73346.1 - 5.5e-05 23.6 2.0 0.031 14.7 0.1 2.5 2 1 0 2 2 2 2 Subunit CCDC53 of WASH complex DUF948 PF06103.11 KNZ73346.1 - 0.16 12.3 1.4 21 5.5 0.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.11 KNZ73346.1 - 0.28 10.7 1.4 5.4 6.5 0.1 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Transketolase_N PF00456.21 KNZ73347.1 - 1.6e-15 56.9 0.5 2.5e-14 53.0 0.5 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 KNZ73347.1 - 5.2e-10 39.3 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 KNZ73347.1 - 1.9e-06 27.7 0.2 4.4e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 KNZ73347.1 - 0.0024 17.7 0.1 0.0089 15.8 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KNZ73347.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component CRIM PF16978.5 KNZ73348.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain Tubulin PF00091.25 KNZ73349.1 - 2.1e-60 204.3 0.0 3e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KNZ73349.1 - 3.7e-37 127.3 0.0 6e-37 126.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KNZ73349.1 - 2.4e-06 27.8 0.0 8.1e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KNZ73349.1 - 0.0019 17.9 0.0 0.0049 16.6 0.0 1.7 2 0 0 2 2 2 1 Tubulin domain ART PF01129.18 KNZ73349.1 - 0.0033 16.8 0.2 0.0054 16.1 0.2 1.3 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase Tubulin_2 PF13809.6 KNZ73349.1 - 0.034 13.3 0.0 0.076 12.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like DUF1479 PF07350.12 KNZ73350.1 - 1.3e-136 455.7 0.0 1.4e-136 455.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 KNZ73350.1 - 0.024 14.9 0.2 1.1 9.5 0.2 3.0 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Complex1_LYR_2 PF13233.6 KNZ73351.1 - 2.2e-20 73.2 0.0 2.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KNZ73351.1 - 1.4e-12 47.5 0.0 2.1e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KNZ73351.1 - 0.029 15.0 0.0 0.048 14.3 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Cyanate_lyase PF02560.14 KNZ73352.1 - 3.7e-33 113.2 0.0 7.5e-33 112.2 0.0 1.5 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.12 KNZ73352.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 zf-C2H2 PF00096.26 KNZ73352.1 - 0.022 15.2 0.6 0.022 15.2 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type HTH_31 PF13560.6 KNZ73352.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain KorB PF08535.10 KNZ73352.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 KorB domain F-box-like PF12937.7 KNZ73353.1 - 6.2e-07 29.2 0.5 2.9e-06 27.1 0.5 2.2 1 0 0 1 1 1 1 F-box-like PIF1 PF05970.14 KNZ73354.1 - 1.6e-08 34.1 0.0 3.4e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase DUF5633 PF18656.1 KNZ73354.1 - 0.15 12.0 0.3 0.26 11.2 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5633) HgmA PF04209.13 KNZ73357.1 - 4.4e-171 569.3 0.0 5.1e-171 569.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AAA PF00004.29 KNZ73358.1 - 7.1e-16 58.8 0.1 1.8e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 KNZ73358.1 - 7.2e-12 45.2 0.0 4.8e-11 42.6 0.0 2.3 3 0 0 3 3 3 1 BAH domain AAA_16 PF13191.6 KNZ73358.1 - 5.3e-10 39.9 0.1 1.1e-08 35.6 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 KNZ73358.1 - 3.2e-07 30.4 0.1 7.6e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KNZ73358.1 - 1.2e-06 28.8 0.0 4.2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 KNZ73358.1 - 0.00039 19.8 0.0 0.00076 18.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KNZ73358.1 - 0.0054 17.1 1.7 0.008 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KNZ73358.1 - 0.03 14.1 1.0 0.041 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KNZ73358.1 - 0.039 13.9 0.0 0.36 10.7 0.0 2.5 2 1 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 KNZ73358.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KNZ73358.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF2568 PF10823.8 KNZ73361.1 - 0.1 12.9 0.5 0.1 12.9 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2568) TMCCDC2 PF15844.5 KNZ73361.1 - 1.6 8.7 4.0 4.5 7.2 0.9 2.2 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Patatin PF01734.22 KNZ73364.1 - 6e-31 108.2 0.0 2.6e-30 106.2 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Abhydrolase_1 PF00561.20 KNZ73365.1 - 2.1e-18 66.9 0.2 1.3e-16 61.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ73365.1 - 9.9e-16 59.0 0.0 1.5e-15 58.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ73365.1 - 1.4e-11 44.2 0.0 2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KNZ73365.1 - 1.9e-07 31.4 0.0 2.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KNZ73365.1 - 2.9e-05 23.9 0.5 0.00038 20.3 0.5 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KNZ73365.1 - 8.2e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KNZ73365.1 - 0.0052 16.6 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 KNZ73365.1 - 0.013 15.2 0.0 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative esterase Abhydrolase_2 PF02230.16 KNZ73365.1 - 0.015 15.1 0.1 0.37 10.6 0.0 2.2 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KNZ73365.1 - 0.022 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KNZ73365.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Palm_thioest PF02089.15 KNZ73365.1 - 0.076 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 KNZ73365.1 - 0.11 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1057 PF06342.12 KNZ73365.1 - 0.23 10.5 0.1 0.72 8.8 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) AAR2 PF05282.11 KNZ73367.1 - 0.24 10.7 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 AAR2 protein Arv1 PF04161.13 KNZ73368.1 - 2.8e-34 119.1 9.5 4.6e-34 118.4 9.5 1.3 1 0 0 1 1 1 1 Arv1-like family DUF410 PF04190.13 KNZ73370.1 - 5.3e-72 242.7 0.0 6.4e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 KNZ73370.1 - 0.25 11.6 0.6 16 5.9 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Helitron_like_N PF14214.6 KNZ73372.1 - 1e-23 84.5 0.6 4e-23 82.6 0.0 2.2 3 0 0 3 3 3 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ73373.1 - 7e-13 48.5 0.0 7.4e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase RT_RNaseH_2 PF17919.1 KNZ73374.1 - 2.3e-09 37.2 0.0 3.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ73374.1 - 0.0062 16.8 0.1 0.012 15.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase MIP PF00230.20 KNZ73376.1 - 1.9e-45 155.4 13.6 2.1e-45 155.2 13.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein HSBP1 PF06825.12 KNZ73377.1 - 4.6e-20 71.2 3.2 6.7e-20 70.7 3.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 FdhE PF04216.12 KNZ73377.1 - 0.034 14.0 0.0 0.04 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation NPV_P10 PF05531.12 KNZ73377.1 - 0.046 14.2 0.5 0.095 13.2 0.5 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GOLGA2L5 PF15070.6 KNZ73377.1 - 0.053 12.2 0.1 0.12 11.0 0.1 1.5 1 1 1 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Baculo_PEP_C PF04513.12 KNZ73377.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 KNZ73377.1 - 0.11 12.3 0.3 1.3 8.9 0.3 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Gti1_Pac2 PF09729.9 KNZ73378.1 - 3.1e-48 164.3 4.8 4e-47 160.6 0.6 2.8 2 1 0 2 2 2 1 Gti1/Pac2 family Ank_4 PF13637.6 KNZ73379.1 - 1.8e-36 124.0 0.2 1.9e-13 50.7 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ73379.1 - 9.2e-33 112.7 0.0 2.4e-16 60.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KNZ73379.1 - 2e-32 110.2 1.9 2.4e-07 30.9 0.0 5.8 5 1 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 KNZ73379.1 - 7.9e-30 99.6 0.1 5.3e-06 26.4 0.0 6.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KNZ73379.1 - 1.2e-28 98.8 1.2 2.4e-05 24.5 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Glyoxalase_6 PF18029.1 KNZ73379.1 - 0.001 19.8 0.4 1 10.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Chromo PF00385.24 KNZ73380.1 - 0.0039 17.1 0.0 0.0048 16.8 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain COesterase PF00135.28 KNZ73381.1 - 4.1e-81 273.4 0.3 1.5e-67 228.6 0.1 2.8 2 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ73381.1 - 8.6e-12 45.4 0.3 7.2e-11 42.3 0.2 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KNZ73381.1 - 0.0038 16.9 0.2 0.02 14.6 0.2 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KNZ73381.1 - 0.0042 16.6 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KNZ73381.1 - 0.083 11.7 0.1 0.57 9.0 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KNZ73382.1 - 5.5e-26 92.5 0.0 9.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ73382.1 - 5.4e-10 39.0 0.0 8.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ73382.1 - 5.9e-07 29.4 0.0 7e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 KNZ73382.1 - 2.2e-05 24.7 0.0 9.5e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KNZ73382.1 - 0.0055 16.5 0.0 0.0088 15.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 KNZ73382.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 KNZ73382.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Peptidase_S28 PF05577.12 KNZ73382.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 AAA PF00004.29 KNZ73383.1 - 7.5e-91 301.4 0.0 8.8e-48 162.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ73383.1 - 4.6e-22 77.6 1.5 6e-10 38.8 0.2 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 KNZ73383.1 - 3.5e-13 49.6 0.0 1.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KNZ73383.1 - 8.5e-13 49.0 0.9 0.0019 18.6 0.0 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 KNZ73383.1 - 3.4e-12 46.8 0.4 0.029 14.6 0.0 5.3 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.14 KNZ73383.1 - 4.9e-10 39.8 0.0 0.00053 20.1 0.0 3.1 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KNZ73383.1 - 6.9e-10 39.1 1.2 0.0023 18.0 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KNZ73383.1 - 1e-09 38.7 0.0 0.00062 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KNZ73383.1 - 9.8e-08 31.6 0.2 0.016 14.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KNZ73383.1 - 1.6e-07 31.6 0.0 0.016 15.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 KNZ73383.1 - 1.9e-07 31.2 0.0 0.026 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KNZ73383.1 - 2.1e-07 31.3 0.0 0.0042 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KNZ73383.1 - 2.3e-07 30.3 0.0 0.0075 15.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 KNZ73383.1 - 6.5e-07 29.3 0.0 0.04 13.6 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 KNZ73383.1 - 8.5e-06 25.9 0.0 0.045 13.9 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.6 KNZ73383.1 - 1.7e-05 25.3 0.0 0.31 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KNZ73383.1 - 2.5e-05 24.3 0.6 0.62 10.0 0.0 3.5 3 1 0 4 4 3 2 NACHT domain ABC_tran PF00005.27 KNZ73383.1 - 3e-05 24.6 0.0 0.3 11.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 KNZ73383.1 - 3.6e-05 23.5 0.0 0.34 10.6 0.0 3.3 3 1 0 3 3 2 2 Sigma-54 interaction domain ATPase PF06745.13 KNZ73383.1 - 4.1e-05 23.1 0.1 1 8.7 0.0 3.2 3 0 0 3 3 3 2 KaiC AAA_3 PF07726.11 KNZ73383.1 - 4.6e-05 23.3 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KNZ73383.1 - 0.00011 22.2 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KNZ73383.1 - 0.0002 20.9 0.0 0.66 9.5 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 KNZ73383.1 - 0.00026 20.6 3.6 2 7.9 0.0 4.1 3 1 0 4 4 4 1 AAA domain DUF815 PF05673.13 KNZ73383.1 - 0.00039 19.7 0.0 0.0086 15.3 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 KNZ73383.1 - 0.00049 19.9 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 KNZ73383.1 - 0.00051 20.0 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain Zeta_toxin PF06414.12 KNZ73383.1 - 0.00054 19.3 0.0 0.69 9.2 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_17 PF13207.6 KNZ73383.1 - 0.00073 20.0 0.0 2.1 8.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 KNZ73383.1 - 0.00091 18.5 0.0 0.71 9.0 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KNZ73383.1 - 0.00095 18.9 0.0 0.9 9.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain Vps4_C PF09336.10 KNZ73383.1 - 0.00098 19.1 0.0 2.5 8.2 0.0 3.0 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain Cytidylate_kin2 PF13189.6 KNZ73383.1 - 0.0013 18.9 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase-like family AAA_11 PF13086.6 KNZ73383.1 - 0.0016 18.3 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KNZ73383.1 - 0.0016 17.9 0.1 2.3 7.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 KNZ73383.1 - 0.0017 17.5 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 KNZ73383.1 - 0.0035 17.3 0.0 1.9 8.3 0.0 2.8 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 KNZ73383.1 - 0.018 14.4 0.0 32 3.9 0.0 3.6 2 1 1 3 3 3 0 Bacterial TniB protein AFG1_ATPase PF03969.16 KNZ73383.1 - 0.027 13.4 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 KNZ73383.1 - 0.03 14.7 1.1 12 6.2 0.2 2.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KNZ73383.1 - 0.06 13.3 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 KNZ73383.1 - 0.099 12.3 0.1 20 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KNZ73383.1 - 0.11 12.3 0.0 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.18 KNZ73383.1 - 0.11 12.3 0.0 4.4 7.1 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein SKI PF01202.22 KNZ73383.1 - 0.12 12.5 0.0 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase SRPRB PF09439.10 KNZ73383.1 - 0.21 11.0 0.0 18 4.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.9 KNZ73383.1 - 0.23 10.7 0.0 21 4.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF829 PF05705.14 KNZ73384.1 - 1e-28 100.8 0.0 1.3e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Retrotran_gag_2 PF14223.6 KNZ73385.1 - 4.6e-09 36.0 0.1 3.2e-08 33.3 0.1 2.0 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.8 KNZ73385.1 - 0.051 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 KNZ73386.1 - 0.084 13.0 1.4 0.18 11.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ73386.1 - 0.43 10.4 2.0 0.72 9.6 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger rve PF00665.26 KNZ73387.1 - 0.0029 17.8 0.0 0.0058 16.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ceramidse_alk_C PF17048.5 KNZ73390.1 - 9.7e-17 61.3 0.1 1.2e-10 41.5 0.0 2.0 2 0 0 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, C-terminal PIF1 PF05970.14 KNZ73391.1 - 1.9e-33 116.1 0.0 2.4e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KNZ73391.1 - 9e-07 27.2 0.0 1.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ73391.1 - 0.00031 20.5 0.0 0.00066 19.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain 4HPAD_g_N PF18671.1 KNZ73391.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal DKCLD PF08068.12 KNZ73392.1 - 3e-33 113.7 0.2 1.7e-32 111.3 0.3 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KNZ73392.1 - 1.6e-23 83.7 0.2 2e-16 60.7 0.1 3.4 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KNZ73392.1 - 2.7e-22 78.7 0.8 5.9e-22 77.6 0.8 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KNZ73392.1 - 5.1e-21 74.4 1.7 5.1e-21 74.4 1.7 1.9 2 0 0 2 2 2 1 PUA domain UPF0113 PF03657.13 KNZ73392.1 - 0.015 15.5 0.0 0.043 14.1 0.0 1.8 1 0 0 1 1 1 0 UPF0113 PUA domain Ribosomal_L22e PF01776.17 KNZ73393.1 - 2.8e-48 162.8 0.2 3.1e-48 162.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HA2 PF04408.23 KNZ73394.1 - 7.9e-18 64.7 0.2 8.7e-17 61.4 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KNZ73394.1 - 8.9e-15 55.0 0.0 2.5e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KNZ73394.1 - 2.6e-10 40.5 0.0 5.6e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KNZ73394.1 - 1.1e-06 29.0 1.5 2.9e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KNZ73394.1 - 0.015 15.8 0.5 0.074 13.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 KNZ73394.1 - 0.025 13.9 0.4 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 KaiC DUF4140 PF13600.6 KNZ73394.1 - 0.18 12.2 1.4 6.5 7.3 1.6 3.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SNF2_N PF00176.23 KNZ73395.1 - 3.2e-53 180.7 2.5 1.4e-52 178.6 1.3 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 KNZ73395.1 - 1.6e-49 167.7 18.7 1.6e-49 167.7 18.7 2.3 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 KNZ73395.1 - 3.7e-16 59.5 0.0 7.6e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KNZ73395.1 - 5e-06 25.9 0.1 9.5e-05 21.7 0.0 2.7 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Lyase_1 PF00206.20 KNZ73396.1 - 3.1e-104 348.7 0.0 3.8e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KNZ73396.1 - 4.6e-12 46.2 0.1 1.1e-11 45.0 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus PEX11 PF05648.14 KNZ73397.1 - 5.9e-51 173.1 0.6 6.7e-51 172.9 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cmc1 PF08583.10 KNZ73398.1 - 9.4e-13 48.0 1.1 1.1e-12 47.7 1.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4839 PF16127.5 KNZ73398.1 - 0.17 12.0 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4839) LIAS_N PF16881.5 KNZ73399.1 - 5.3e-24 84.7 0.0 1.2e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KNZ73399.1 - 2.5e-14 54.0 0.0 5.3e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Ribosomal_S28e PF01200.18 KNZ73400.1 - 5.7e-29 99.9 1.5 6.6e-29 99.7 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.20 KNZ73401.1 - 3.9e-15 56.1 0.0 5.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_24 PF18404.1 KNZ73401.1 - 0.032 13.6 0.1 0.05 13.0 0.1 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 Peptidase_M22 PF00814.25 KNZ73402.1 - 2.9e-77 260.0 0.1 6.1e-77 259.0 0.0 1.6 2 0 0 2 2 2 1 Glycoprotease family 2-oxoacid_dh PF00198.23 KNZ73403.1 - 3.3e-69 232.9 0.0 2.9e-36 125.1 0.0 2.1 1 1 1 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KNZ73403.1 - 6.6e-18 64.3 1.5 1.7e-17 63.0 1.5 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KNZ73403.1 - 6.3e-13 48.8 0.3 1.3e-12 47.8 0.3 1.6 1 0 0 1 1 1 1 e3 binding domain PE PF00934.20 KNZ73403.1 - 0.053 13.9 0.3 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 PE family EXOSC1 PF10447.9 KNZ73404.1 - 7.1e-18 65.2 1.4 1.6e-13 51.2 0.3 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KNZ73404.1 - 0.031 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region Agarase_CBM PF17992.1 KNZ73404.1 - 0.063 12.8 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Agarase CBM like domain Es2 PF09751.9 KNZ73405.1 - 3.5e-64 218.2 13.3 3.5e-64 218.2 13.3 3.4 3 1 1 4 4 4 1 Nuclear protein Es2 NUDE_C PF04880.13 KNZ73405.1 - 2.2e-05 25.0 29.1 2.2e-05 25.0 29.1 7.3 4 2 2 6 6 6 1 NUDE protein, C-terminal conserved region PRKG1_interact PF15898.5 KNZ73405.1 - 0.0018 19.1 10.5 0.0018 19.1 10.5 4.2 4 1 1 5 5 5 1 cGMP-dependent protein kinase interacting domain Flg_hook PF02120.16 KNZ73405.1 - 0.027 14.4 9.7 0.032 14.1 0.9 3.4 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK DUF2353 PF09789.9 KNZ73405.1 - 0.052 12.9 20.1 0.13 11.5 20.1 1.6 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) YiiD_C PF09500.10 KNZ73405.1 - 0.12 12.2 0.2 0.98 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative thioesterase (yiiD_Cterm) HrpB7 PF09486.10 KNZ73405.1 - 0.52 10.7 18.9 1.3 9.4 6.7 3.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Occludin_ELL PF07303.13 KNZ73405.1 - 1.4 9.7 10.0 0.7 10.7 0.9 3.0 2 1 1 3 3 3 0 Occludin homology domain Syntaxin-6_N PF09177.11 KNZ73405.1 - 9.7 6.8 20.3 4.4 7.9 2.8 4.0 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Nefa_Nip30_N PF10187.9 KNZ73406.1 - 9.1e-23 80.6 9.5 1.5e-22 79.9 9.5 1.4 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 FUSC PF04632.12 KNZ73406.1 - 0.19 10.2 0.1 0.23 10.0 0.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family SLX9 PF15341.6 KNZ73408.1 - 1.7e-19 70.5 5.2 2.4e-19 70.0 5.2 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 EamA PF00892.20 KNZ73408.1 - 1e-09 38.7 36.0 3.5e-08 33.7 12.6 2.9 2 1 0 2 2 2 2 EamA-like transporter family DUF3955 PF13127.6 KNZ73408.1 - 1.4e-06 28.0 1.8 1.4e-06 28.0 1.8 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 KNZ73408.1 - 7.3e-06 25.7 19.3 6.7e-05 22.5 17.0 2.2 2 0 0 2 2 2 1 Solute carrier family 35 DUF4686 PF15742.5 KNZ73408.1 - 0.038 13.1 1.8 0.051 12.7 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) DUF4094 PF13334.6 KNZ73408.1 - 2.5 8.6 4.5 0.51 10.8 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Ank_4 PF13637.6 KNZ73409.1 - 3.8e-11 43.3 0.3 0.0002 21.9 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ73409.1 - 6.1e-11 42.8 0.1 1.8e-06 28.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ73409.1 - 1.2e-10 40.6 0.3 0.00014 22.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KNZ73409.1 - 1.3e-10 41.3 0.5 2.5e-08 34.0 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KNZ73409.1 - 7.4e-09 35.7 0.8 1.6e-05 25.2 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat HAP1_N PF04849.13 KNZ73410.1 - 1.2e-05 24.7 24.9 0.16 11.1 17.6 3.3 3 0 0 3 3 3 3 HAP1 N-terminal conserved region Macoilin PF09726.9 KNZ73410.1 - 0.0017 17.1 12.2 0.0017 17.1 12.2 3.3 3 1 0 3 3 3 1 Macoilin family FapA PF03961.13 KNZ73410.1 - 0.05 12.2 6.2 0.11 11.1 6.2 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cep57_CLD_2 PF14197.6 KNZ73410.1 - 1 9.5 25.6 0.025 14.6 9.5 4.6 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 Golgin_A5 PF09787.9 KNZ73410.1 - 1.8 8.0 23.0 0.12 11.9 16.4 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 TSC22 PF01166.18 KNZ73410.1 - 4 7.8 11.1 9 6.7 0.7 3.9 4 0 0 4 4 4 0 TSC-22/dip/bun family YabA PF06156.13 KNZ73410.1 - 5.1 7.8 18.9 5.7 7.6 0.1 4.4 3 1 1 4 4 4 0 Initiation control protein YabA Rad51 PF08423.11 KNZ73411.1 - 5e-09 35.8 0.0 7.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KNZ73411.1 - 0.0019 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PPR_2 PF13041.6 KNZ73412.1 - 1.4e-31 108.5 0.1 3e-09 36.9 0.0 7.3 5 3 4 9 9 9 6 PPR repeat family PPR_3 PF13812.6 KNZ73412.1 - 4.4e-26 90.7 0.0 6.3e-08 32.6 0.0 6.7 4 2 3 7 7 7 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 KNZ73412.1 - 2e-22 78.6 2.6 1.6e-08 34.1 0.0 6.8 7 0 0 7 7 7 3 PPR repeat PPR PF01535.20 KNZ73412.1 - 1.1e-18 66.1 7.9 2.9e-07 30.3 0.0 6.7 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 KNZ73412.1 - 3.3e-14 52.8 0.1 2.5e-10 40.1 0.0 3.7 4 0 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KNZ73412.1 - 2.7e-05 24.6 0.0 0.72 10.8 0.0 5.7 4 2 1 5 5 5 1 Tetratricopeptide repeat Hap4_Hap_bind PF10297.9 KNZ73413.1 - 3e-06 27.1 3.6 7e-06 26.0 3.6 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KNZ73413.1 - 2.5e-05 24.3 12.2 2.5e-05 24.3 12.2 1.9 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 KNZ73413.1 - 0.0043 17.1 13.1 0.016 15.3 2.4 2.3 2 0 0 2 2 2 2 Basic region leucine zipper HAUS-augmin3 PF14932.6 KNZ73413.1 - 0.28 10.7 4.7 0.42 10.1 4.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Sugar_tr PF00083.24 KNZ73414.1 - 4.4e-44 151.1 25.5 3.6e-42 144.8 25.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ73414.1 - 2.7e-16 59.5 43.7 9.5e-09 34.6 21.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 KNZ73414.1 - 0.069 13.4 0.2 0.069 13.4 0.2 3.9 4 0 0 4 4 4 0 Putative inner membrane exporter, YdcZ Phage_GPO PF05929.11 KNZ73416.1 - 0.15 11.7 3.2 0.091 12.4 1.3 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Hepar_II_III PF07940.13 KNZ73418.1 - 0.061 12.9 0.0 0.072 12.7 0.0 1.0 1 0 0 1 1 1 0 Heparinase II/III-like protein DUF1154 PF06631.11 KNZ73419.1 - 0.069 13.2 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Glyco_hydro_3_C PF01915.22 KNZ73420.1 - 9.6e-39 133.4 0.1 3.2e-36 125.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ73420.1 - 5.3e-21 75.3 0.0 7.3e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ73420.1 - 0.00089 19.3 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3445 PF11927.8 KNZ73421.1 - 5.7e-72 242.0 0.0 7.1e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Mt_ATP-synt_D PF05873.12 KNZ73422.1 - 1.2e-16 61.0 0.9 1.5e-16 60.6 0.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Glyco_hydro_35 PF01301.19 KNZ73423.1 - 5.6e-85 285.8 0.5 8.2e-85 285.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KNZ73423.1 - 4.2e-57 191.7 5.9 2.4e-33 115.1 0.6 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KNZ73423.1 - 4.7e-44 150.3 1.4 1.1e-43 149.1 1.4 1.7 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KNZ73423.1 - 1.5e-21 75.7 0.2 4.7e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 A_deamin PF02137.18 KNZ73424.1 - 2.6e-46 158.6 0.0 3.2e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain SNAD4 PF18750.1 KNZ73424.1 - 0.26 11.4 0.3 0.54 10.4 0.0 1.6 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 MCC-bdg_PDZ PF10506.9 KNZ73427.1 - 0.18 11.8 1.3 0.22 11.6 0.1 1.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Herpes_Helicase PF02689.14 KNZ73428.1 - 1.6e-06 26.4 0.0 1.7e-06 26.3 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ73428.1 - 0.06 13.2 0.1 0.15 11.9 0.1 1.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Pex24p PF06398.11 KNZ73429.1 - 3.1e-07 29.7 2.2 4.4e-07 29.2 2.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rad21_Rec8_N PF04825.13 KNZ73429.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein CRPV_capsid PF08762.10 KNZ73429.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 CRPV capsid protein like HA2 PF04408.23 KNZ73430.1 - 2.1e-17 63.3 0.0 4.8e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KNZ73430.1 - 8.6e-14 51.8 0.0 3.9e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.26 KNZ73430.1 - 1.6e-08 35.2 0.0 0.00063 20.4 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif DEAD PF00270.29 KNZ73430.1 - 6.6e-08 32.5 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KNZ73430.1 - 0.00054 20.3 0.1 0.0036 17.6 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 KNZ73430.1 - 0.0011 19.3 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Dicer_dimer PF03368.14 KNZ73430.1 - 0.003 17.7 0.0 0.011 15.8 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 KNZ73430.1 - 0.1 12.6 0.0 0.42 10.6 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Adaptin_N PF01602.20 KNZ73431.1 - 4.5e-123 411.6 6.1 6.3e-123 411.1 6.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KNZ73431.1 - 4.8e-39 133.0 0.0 1e-38 132.0 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KNZ73431.1 - 1.3e-15 57.7 0.0 3.5e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 KNZ73431.1 - 0.061 13.6 0.3 1.3 9.5 0.1 3.3 3 0 0 3 3 3 0 HEAT repeat RTP1_C1 PF10363.9 KNZ73431.1 - 0.064 13.4 0.5 0.2 11.9 0.5 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGAP PF00616.19 KNZ73432.1 - 2e-28 99.5 0.0 1.9e-21 76.7 0.1 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KNZ73432.1 - 6e-07 29.7 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain ELO PF01151.18 KNZ73433.1 - 3.7e-59 200.3 17.2 4.2e-59 200.1 17.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CitMHS PF03600.16 KNZ73433.1 - 0.3 10.2 3.5 0.32 10.1 3.5 1.2 1 0 0 1 1 1 0 Citrate transporter gag-asp_proteas PF13975.6 KNZ73435.1 - 0.00096 19.7 0.0 0.001 19.6 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ73435.1 - 0.0024 18.5 0.0 0.0028 18.2 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease VPS13_mid_rpt PF16910.5 KNZ73436.1 - 2.8e-91 305.1 8.7 1.2e-87 293.3 1.4 4.5 3 1 1 4 4 4 3 Repeating coiled region of VPS13 VPS13 PF16908.5 KNZ73436.1 - 1.4e-75 254.2 0.7 2.4e-71 240.3 0.1 3.5 3 0 0 3 3 3 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KNZ73436.1 - 7.2e-70 234.4 5.3 1.5e-66 223.5 0.1 3.1 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 KNZ73436.1 - 6e-59 199.6 0.0 1.5e-56 191.8 0.0 3.6 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 KNZ73436.1 - 6.1e-28 97.3 0.2 1.6e-27 95.9 0.2 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 KNZ73436.1 - 2.6e-08 34.1 0.0 9.9e-08 32.2 0.0 2.0 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DENN PF02141.21 KNZ73437.1 - 8.1e-19 68.3 0.0 3.5e-18 66.2 0.0 2.2 2 0 0 2 2 2 1 DENN (AEX-3) domain ADIP PF11559.8 KNZ73437.1 - 0.011 15.9 9.7 0.011 15.9 9.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding OmpH PF03938.14 KNZ73437.1 - 0.036 14.4 9.9 0.088 13.1 9.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lum_binding PF00677.17 KNZ73437.1 - 0.077 13.0 0.0 0.38 10.8 0.0 2.2 1 0 0 1 1 1 0 Lumazine binding domain FAM184 PF15665.5 KNZ73437.1 - 0.1 12.3 13.7 0.22 11.3 13.7 1.5 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B GAS PF13851.6 KNZ73437.1 - 0.13 11.6 13.4 0.3 10.4 13.4 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 KNZ73437.1 - 0.14 12.8 7.5 5.6 7.7 0.4 2.8 2 0 0 2 2 2 0 Initiation control protein YabA SLATT_1 PF18181.1 KNZ73437.1 - 0.23 11.4 2.6 0.61 10.0 2.6 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 APG6_N PF17675.1 KNZ73437.1 - 0.35 11.4 14.6 1.1 9.7 14.6 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region EspB_PE PF18625.1 KNZ73437.1 - 0.66 10.5 4.5 0.55 10.7 0.4 2.6 1 1 1 2 2 2 0 ESX-1 secreted protein B PE domain FapA PF03961.13 KNZ73437.1 - 3.2 6.2 9.1 6.4 5.3 9.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Tup_N PF08581.10 KNZ73437.1 - 4 7.8 11.0 1.5 9.2 6.2 2.5 2 1 0 2 2 2 0 Tup N-terminal DUF4407 PF14362.6 KNZ73437.1 - 8.9 5.6 13.8 2.9 7.2 8.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mg_trans_NIPA PF05653.14 KNZ73438.1 - 5.9e-19 68.3 16.1 5.5e-10 38.8 2.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA AAA_2 PF07724.14 KNZ73439.1 - 1.8e-50 171.4 0.0 1.2e-45 155.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KNZ73439.1 - 4.5e-33 113.3 1.2 4.5e-33 113.3 1.2 3.0 4 0 0 4 4 2 1 AAA lid domain AAA PF00004.29 KNZ73439.1 - 9.9e-25 87.5 0.0 1.6e-13 51.3 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KNZ73439.1 - 1.5e-21 76.2 0.2 9e-21 73.7 0.2 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 KNZ73439.1 - 4.2e-14 52.4 1.8 1.4e-10 41.1 0.3 4.1 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 KNZ73439.1 - 1.4e-13 51.0 0.1 2e-06 27.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ73439.1 - 1.3e-12 48.5 0.3 1.7e-05 25.3 0.0 4.3 3 1 1 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KNZ73439.1 - 4.3e-08 33.1 0.0 5.8e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 KNZ73439.1 - 8.7e-08 32.5 0.0 0.044 14.1 0.0 4.1 2 2 1 3 3 2 2 AAA domain IstB_IS21 PF01695.17 KNZ73439.1 - 3e-07 30.4 0.0 0.0016 18.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KNZ73439.1 - 8.2e-07 28.6 0.2 0.0027 17.1 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 KNZ73439.1 - 1.9e-06 27.8 0.0 0.0084 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 KNZ73439.1 - 1e-05 24.9 2.2 0.04 13.1 0.0 3.4 3 1 1 4 4 3 2 TIP49 P-loop domain TniB PF05621.11 KNZ73439.1 - 6.3e-05 22.5 0.1 0.15 11.4 0.0 3.8 3 1 0 3 3 3 1 Bacterial TniB protein AAA_18 PF13238.6 KNZ73439.1 - 0.0001 22.9 0.5 0.23 12.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 KNZ73439.1 - 0.00012 22.1 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 KNZ73439.1 - 0.00014 22.2 0.3 0.95 9.9 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.6 KNZ73439.1 - 0.00018 21.7 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KNZ73439.1 - 0.00018 21.3 0.0 1.3 8.8 0.0 3.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KNZ73439.1 - 0.00048 19.7 0.0 0.89 9.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 KNZ73439.1 - 0.0006 19.2 0.0 0.079 12.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 KNZ73439.1 - 0.0014 19.1 1.7 1.2 9.7 0.0 3.5 3 0 0 3 3 3 1 ABC transporter Torsin PF06309.11 KNZ73439.1 - 0.0017 18.4 0.2 0.05 13.7 0.0 2.9 4 0 0 4 4 2 1 Torsin PhoH PF02562.16 KNZ73439.1 - 0.0021 17.6 0.0 0.39 10.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 KNZ73439.1 - 0.0037 17.5 1.8 1.3 9.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 KNZ73439.1 - 0.0052 17.0 0.0 0.6 10.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 KNZ73439.1 - 0.0063 16.5 0.0 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KNZ73439.1 - 0.011 15.5 0.0 3.4 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.12 KNZ73439.1 - 0.012 15.6 1.6 0.031 14.3 1.6 1.7 1 0 0 1 1 1 0 Laminin Domain II AAA_14 PF13173.6 KNZ73439.1 - 0.014 15.4 0.0 2.6 8.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KNZ73439.1 - 0.021 15.1 0.0 4.5 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 KNZ73439.1 - 0.03 14.4 0.1 11 6.1 0.0 3.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KNZ73439.1 - 0.031 13.8 0.8 8.3 5.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KNZ73439.1 - 0.032 14.1 0.0 4.8 7.1 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase T2SSE PF00437.20 KNZ73439.1 - 0.034 13.2 0.5 0.12 11.5 0.0 2.0 3 0 0 3 3 2 0 Type II/IV secretion system protein Pox_A_type_inc PF04508.12 KNZ73439.1 - 0.052 13.4 0.3 0.46 10.4 0.3 2.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat ResIII PF04851.15 KNZ73439.1 - 0.08 12.9 0.0 3.5 7.6 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 KNZ73439.1 - 0.081 12.8 0.4 5 7.0 0.0 3.2 3 0 0 3 3 2 0 NTPase APS_kinase PF01583.20 KNZ73439.1 - 0.081 12.8 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_3 PF07726.11 KNZ73439.1 - 0.084 12.7 0.0 41 4.0 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KNZ73439.1 - 0.1 12.3 0.0 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hemagglutinin PF00509.18 KNZ73439.1 - 0.14 10.5 0.5 0.22 9.9 0.5 1.2 1 0 0 1 1 1 0 Haemagglutinin UPF0242 PF06785.11 KNZ73439.1 - 0.39 10.8 4.9 0.89 9.6 4.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 KNZ73439.1 - 0.69 10.4 17.0 7.9 6.9 0.0 3.7 3 1 0 3 3 3 0 AAA domain ATPase PF06745.13 KNZ73439.1 - 0.71 9.2 4.9 6 6.1 0.0 3.8 3 1 1 4 4 4 0 KaiC DUF724 PF05266.14 KNZ73439.1 - 0.79 9.5 9.2 2 8.2 9.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Uds1 PF15456.6 KNZ73439.1 - 1.1 9.4 9.9 3.6 7.8 9.9 1.9 1 0 0 1 1 1 0 Up-regulated During Septation DUF4140 PF13600.6 KNZ73439.1 - 1.4 9.4 11.0 5.8 7.4 1.2 3.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 KNZ73439.1 - 1.7 7.6 9.7 2.8 6.9 9.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PV-1 PF06637.11 KNZ73439.1 - 2.6 6.8 9.7 4.2 6.1 9.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF4407 PF14362.6 KNZ73439.1 - 2.6 7.3 6.6 4.4 6.6 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 KNZ73439.1 - 3.5 6.4 13.8 0.74 8.6 10.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein 5_nucleotid PF05761.14 KNZ73439.1 - 4.2 6.1 4.8 7.2 5.4 4.8 1.3 1 0 0 1 1 1 0 5' nucleotidase family INCENP_ARK-bind PF03941.15 KNZ73440.1 - 1.2e-21 76.4 0.7 1.2e-21 76.4 0.7 2.4 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region ARGLU PF15346.6 KNZ73440.1 - 1.3 8.9 30.8 0.097 12.5 24.9 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DCP2 PF05026.13 KNZ73441.1 - 7.9e-33 112.6 1.6 1.5e-32 111.7 1.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KNZ73441.1 - 1.2e-08 35.0 0.0 5.6e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain PARP PF00644.20 KNZ73442.1 - 4.7e-10 39.4 0.0 1.3e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KNZ73442.1 - 0.0087 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KNZ73442.1 - 0.13 12.6 0.0 0.77 10.1 0.0 2.3 2 0 0 2 2 2 0 RWD domain Opiods_neuropep PF01160.18 KNZ73442.1 - 1.7 8.8 3.5 5 7.3 3.5 1.8 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Tubulin_2 PF13809.6 KNZ73443.1 - 0.078 12.2 0.0 0.095 11.9 0.0 1.1 1 0 0 1 1 1 0 Tubulin like zf-CHCC PF10276.9 KNZ73444.1 - 6.8e-12 45.2 0.7 1.1e-11 44.6 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.25 KNZ73445.1 - 3e-50 171.1 0.0 4.2e-49 167.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73445.1 - 1.3e-22 80.3 0.0 3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase V-ATPase_G_2 PF16999.5 KNZ73445.1 - 0.027 14.9 5.6 0.047 14.1 5.6 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2956 PF11169.8 KNZ73445.1 - 1.9 8.8 6.4 4.1 7.6 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Pribosyltran_N PF13793.6 KNZ73446.1 - 9.1e-46 154.6 0.8 5.5e-44 148.8 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KNZ73446.1 - 7.2e-38 130.5 4.2 1.1e-32 113.6 0.9 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KNZ73446.1 - 2e-14 53.4 1.7 2.6e-14 53.1 0.4 1.8 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KNZ73446.1 - 0.00085 18.8 0.2 0.0016 17.9 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF848 PF05852.11 KNZ73446.1 - 0.19 11.8 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) ECH_1 PF00378.20 KNZ73447.1 - 1.5e-36 126.0 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ73447.1 - 5.7e-19 68.8 0.0 7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HSCB_C PF07743.13 KNZ73449.1 - 1.3e-15 57.7 2.1 1.3e-15 57.7 2.1 1.5 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 KNZ73449.1 - 0.00012 22.1 0.0 0.0012 18.9 0.0 2.6 2 1 0 2 2 2 1 DnaJ domain Wbp11 PF09429.10 KNZ73449.1 - 0.048 14.1 1.0 0.15 12.5 0.4 2.0 2 0 0 2 2 2 0 WW domain binding protein 11 DUF4327 PF14217.6 KNZ73449.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) AMP-binding PF00501.28 KNZ73451.1 - 6.6e-62 209.5 0.1 1.5e-37 129.2 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ73451.1 - 1.7e-20 73.7 0.1 4.4e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GYF PF02213.16 KNZ73452.1 - 8.9e-16 57.3 0.0 1.9e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 KNZ73452.1 - 0.0099 15.7 0.2 0.053 13.3 0.0 2.2 3 0 0 3 3 3 1 GYF domain 2 FAD-oxidase_C PF02913.19 KNZ73453.1 - 3.4e-55 187.4 0.0 4.3e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KNZ73453.1 - 2.2e-35 121.4 0.2 4.4e-35 120.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BRCT_2 PF16589.5 KNZ73454.1 - 9.5e-12 45.2 0.0 1.6e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 KNZ73454.1 - 1.8e-08 34.4 1.3 5.7e-08 32.8 1.3 1.9 1 1 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 KNZ73454.1 - 0.75 10.4 5.3 1.2 9.8 2.0 2.9 2 1 0 2 2 2 0 Rap1, DNA-binding Pkinase PF00069.25 KNZ73455.1 - 1.3e-51 175.5 0.0 1.4e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73455.1 - 2.8e-19 69.4 0.0 3.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ73455.1 - 6.7e-05 22.3 0.1 0.0001 21.8 0.1 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KNZ73455.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KNZ73455.1 - 0.18 10.7 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain TTL PF03133.15 KNZ73456.1 - 1.1e-47 162.6 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family MMM1 PF10296.9 KNZ73457.1 - 1.5e-37 129.4 0.3 6.7e-26 91.1 0.0 3.0 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 RNA_pol_Rpb8 PF03870.15 KNZ73459.1 - 5e-48 162.8 0.0 5.8e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 Sec7 PF01369.20 KNZ73460.1 - 8.6e-32 110.3 0.0 1.5e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KNZ73460.1 - 3.7e-10 40.2 0.1 7.6e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KNZ73460.1 - 3.4e-09 37.1 0.1 7.9e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.11 KNZ73461.1 - 8.7e-122 405.9 0.0 8.7e-122 405.9 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 KNZ73461.1 - 2.9e-08 34.0 0.0 1e-07 32.3 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DNA_mis_repair PF01119.19 KNZ73461.1 - 0.0073 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain LIG3_BRCT PF16759.5 KNZ73461.1 - 0.008 16.4 0.0 0.028 14.7 0.0 2.0 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 KNZ73461.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SurA_N_2 PF13623.6 KNZ73461.1 - 0.057 13.3 0.2 0.17 11.7 0.2 1.8 1 0 0 1 1 1 0 SurA N-terminal domain DWNN PF08783.11 KNZ73461.1 - 0.069 13.4 0.4 0.069 13.4 0.4 2.1 2 0 0 2 2 2 0 DWNN domain LSM PF01423.22 KNZ73462.1 - 1.9e-05 24.3 0.3 9.7e-05 22.0 0.1 2.0 2 0 0 2 2 2 1 LSM domain Hfq PF17209.3 KNZ73462.1 - 0.033 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Hfq protein FHIPEP PF00771.20 KNZ73462.1 - 0.033 12.7 1.1 0.043 12.3 1.1 1.2 1 0 0 1 1 1 0 FHIPEP family RdRP PF05183.12 KNZ73463.1 - 4.1e-165 550.8 0.0 6.6e-165 550.1 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3107 PF11305.8 KNZ73463.1 - 0.16 12.2 0.0 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3107) Complex1_LYR PF05347.15 KNZ73464.1 - 4.1e-10 39.5 0.0 5.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Cyclin_N PF00134.23 KNZ73466.1 - 4.4e-37 126.7 0.5 4.4e-37 126.7 0.5 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KNZ73466.1 - 1.7e-08 34.5 0.2 4.4e-08 33.2 0.2 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain GFO_IDH_MocA PF01408.22 KNZ73467.1 - 1.8e-09 38.5 0.4 1e-08 36.0 0.4 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Hydrolase PF00702.26 KNZ73467.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sacchrp_dh_NADP PF03435.18 KNZ73467.1 - 0.13 12.5 0.0 0.57 10.4 0.0 1.9 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Isochorismatase PF00857.20 KNZ73467.1 - 0.15 12.2 0.0 0.93 9.6 0.0 2.3 2 0 0 2 2 2 0 Isochorismatase family WAC_Acf1_DNA_bd PF10537.9 KNZ73469.1 - 2.3e-33 114.7 1.3 2.3e-33 114.7 1.3 2.5 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KNZ73469.1 - 3.7e-31 107.5 0.1 3.7e-31 107.5 0.1 2.7 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KNZ73469.1 - 2.3e-13 50.2 0.5 6e-13 48.9 0.5 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KNZ73469.1 - 8.2e-08 31.6 0.0 1.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CENP-H PF05837.12 KNZ73469.1 - 0.036 14.5 0.8 0.036 14.5 0.8 3.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF3287 PF11690.8 KNZ73469.1 - 0.16 11.7 2.3 4.3 7.1 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF4407 PF14362.6 KNZ73469.1 - 4.9 6.4 10.2 1.4 8.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Aa_trans PF01490.18 KNZ73470.1 - 2.8e-55 187.7 27.7 3.4e-55 187.4 27.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KNZ73470.1 - 0.00046 19.3 12.2 0.00046 19.3 12.2 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CSN8_PSD8_EIF3K PF10075.9 KNZ73471.1 - 2.2e-22 79.6 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF592 PF04574.13 KNZ73471.1 - 0.05 13.4 0.0 7.2 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF592) WD40 PF00400.32 KNZ73472.1 - 9e-49 162.4 14.0 4.3e-10 40.0 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ73472.1 - 7.2e-19 67.9 0.6 9.2e-05 22.7 0.0 4.9 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ73472.1 - 7.3e-10 39.0 0.1 0.0042 17.0 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KNZ73472.1 - 1.1e-08 34.8 0.0 1.3e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KNZ73472.1 - 2.2e-07 30.2 1.1 0.012 14.5 0.2 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KNZ73472.1 - 0.00034 19.8 0.1 0.0025 16.9 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region RAB3GAP2_N PF14655.6 KNZ73472.1 - 0.00065 19.1 0.0 0.0021 17.4 0.0 1.9 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 KNZ73472.1 - 0.0087 14.8 5.6 5.8 5.4 0.1 4.4 1 1 2 4 4 4 2 Nucleoporin Nup120/160 IKI3 PF04762.12 KNZ73472.1 - 0.011 13.8 0.0 0.023 12.7 0.0 1.5 1 0 0 1 1 1 0 IKI3 family Kelch_6 PF13964.6 KNZ73472.1 - 0.027 14.8 0.6 0.92 9.9 0.0 3.4 4 0 0 4 4 4 0 Kelch motif Pectate_lyase22 PF14583.6 KNZ73472.1 - 0.052 12.2 0.4 0.12 11.0 0.1 1.7 2 1 0 2 2 2 0 Oligogalacturonate lyase PALB2_WD40 PF16756.5 KNZ73472.1 - 0.29 10.0 1.9 9.7 5.0 0.1 3.1 1 1 4 5 5 5 0 Partner and localizer of BRCA2 WD40 domain ubiquitin PF00240.23 KNZ73473.1 - 4.5e-137 446.0 18.7 1.3e-33 114.6 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 KNZ73473.1 - 2.8e-63 209.7 20.7 3e-15 55.8 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KNZ73473.1 - 3.5e-23 81.8 9.2 0.00045 20.6 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 KNZ73473.1 - 4e-16 58.7 3.0 0.033 14.1 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KNZ73473.1 - 1.4e-14 54.2 7.5 0.044 14.1 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KNZ73473.1 - 1.6e-14 54.0 2.7 0.11 12.6 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KNZ73473.1 - 5e-13 49.5 1.1 0.36 11.4 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 KNZ73473.1 - 5.3e-10 39.4 0.4 1.1 9.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 KNZ73473.1 - 4.3e-07 29.9 24.6 16 5.7 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 KNZ73473.1 - 5.1e-07 29.3 0.6 1 8.7 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 KNZ73473.1 - 3.9e-06 26.9 2.8 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 KNZ73473.1 - 4.4e-06 27.4 0.1 30 5.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 KNZ73473.1 - 5.6e-06 26.7 0.0 30 5.1 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 KNZ73473.1 - 1e-05 25.3 3.8 11 5.9 0.0 4.3 4 0 0 4 4 4 0 ACT domain TmoB PF06234.12 KNZ73473.1 - 1.1e-05 25.4 0.1 29 4.9 0.0 4.8 4 0 0 4 4 4 0 Toluene-4-monooxygenase system protein B (TmoB) UDP-g_GGTase PF06427.11 KNZ73473.1 - 5.6e-05 23.2 3.2 6.9 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KNZ73473.1 - 0.00034 20.1 0.0 21 4.4 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 KNZ73473.1 - 0.00036 21.1 0.9 73 4.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF493 PF04359.14 KNZ73473.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 KNZ73473.1 - 0.007 16.5 0.0 91 3.3 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 KNZ73473.1 - 0.011 15.9 5.3 64 3.8 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 KNZ73473.1 - 0.041 13.7 9.2 43 4.1 0.1 4.4 4 0 0 4 4 4 0 FlgD Ig-like domain Tash_PEST PF07708.11 KNZ73473.1 - 0.14 12.3 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif DMA PF03474.14 KNZ73473.1 - 0.28 10.8 4.0 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 DMRTA motif Phage_sheath_1N PF17481.2 KNZ73473.1 - 0.44 11.0 9.2 46 4.6 1.3 4.0 1 1 2 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 KNZ73473.1 - 1.1 9.5 4.6 2.4e+02 2.0 0.0 4.0 4 0 0 4 4 4 0 Flagellar protein YcgR PI3K_p85B PF02192.16 KNZ73473.1 - 1.2 9.0 8.5 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 KNZ73473.1 - 1.2 9.3 9.9 1e+02 3.2 0.1 4.4 4 0 0 4 4 4 0 Cnl2/NKP2 family protein Fcf1 PF04900.12 KNZ73474.1 - 1.5e-34 118.3 0.1 1.5e-34 118.3 0.1 1.8 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KNZ73474.1 - 0.0021 18.4 0.0 0.0037 17.6 0.0 1.4 1 0 0 1 1 1 1 PIN like domain DUF2012 PF09430.10 KNZ73475.1 - 1.8e-22 79.8 0.0 2.7e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 KNZ73475.1 - 0.039 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 KNZ73475.1 - 0.04 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II SOP4 PF17081.5 KNZ73475.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein CAP PF00188.26 KNZ73477.1 - 2.6e-24 86.5 1.5 2.6e-24 86.5 1.5 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family XRCC4 PF06632.12 KNZ73477.1 - 0.23 10.3 0.0 0.45 9.3 0.0 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cortexin PF11057.8 KNZ73478.1 - 0.019 14.8 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Cortexin of kidney ABC_sub_bind PF04392.12 KNZ73478.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein FAD_binding_6 PF00970.24 KNZ73479.1 - 6.6e-36 122.6 0.0 1.1e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KNZ73479.1 - 2.8e-28 98.7 0.0 4.3e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KNZ73479.1 - 7.4e-06 26.2 0.0 8.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KNZ73479.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DSPc PF00782.20 KNZ73480.1 - 4e-19 68.7 0.0 2.2e-17 63.1 0.0 2.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ73480.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF846 PF05832.12 KNZ73481.1 - 2.8e-53 179.7 7.2 3.5e-53 179.4 7.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) UbiA PF01040.18 KNZ73481.1 - 0.031 13.6 9.6 0.66 9.2 0.7 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family Adeno_E3B PF03376.14 KNZ73481.1 - 5 7.4 9.8 0.8 10.0 2.2 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein ArsA_ATPase PF02374.15 KNZ73482.1 - 0.1 11.7 0.1 0.21 10.7 0.0 1.4 2 0 0 2 2 2 0 Anion-transporting ATPase LRR_6 PF13516.6 KNZ73483.1 - 1.7e-07 30.7 2.9 1.4 9.2 0.0 7.2 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KNZ73483.1 - 2.8e-07 30.7 9.9 0.48 10.9 0.1 7.3 3 2 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ73483.1 - 0.0015 18.3 5.7 0.53 10.1 0.1 5.2 4 1 0 4 4 4 2 Leucine rich repeat BNR PF02012.20 KNZ73484.1 - 1.7e-06 27.1 15.6 2.3 8.6 0.4 7.8 7 0 0 7 7 7 4 BNR/Asp-box repeat BNR_6 PF15899.5 KNZ73484.1 - 0.001 18.9 4.3 3.8 7.9 0.1 4.9 4 0 0 4 4 4 2 BNR-Asp box repeat LBR_tudor PF09465.10 KNZ73486.1 - 0.085 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Asp_protease_2 PF13650.6 KNZ73487.1 - 0.0039 17.8 0.0 0.02 15.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ73487.1 - 0.012 16.1 0.0 0.05 14.2 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KNZ73487.1 - 0.096 12.5 0.0 8.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease AA_permease PF00324.21 KNZ73488.1 - 6.2e-124 414.2 33.8 7.6e-124 413.9 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ73488.1 - 3.7e-32 111.7 36.2 4.5e-32 111.4 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ73489.1 - 1.3e-123 413.1 37.2 1.8e-123 412.7 37.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ73489.1 - 1e-33 116.8 37.0 1.3e-33 116.5 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease RhoGEF PF00621.20 KNZ73490.1 - 3.7e-41 141.4 0.0 6e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.7 KNZ73490.1 - 0.0037 17.6 1.1 1.8 9.1 0.0 2.9 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ73490.1 - 0.011 15.5 4.5 0.032 14.0 0.0 3.0 2 1 2 4 4 4 0 Leucine rich repeat PH PF00169.29 KNZ73490.1 - 0.12 12.9 0.0 0.89 10.1 0.0 2.4 2 0 0 2 2 2 0 PH domain PAXNEB PF05625.11 KNZ73491.1 - 2.1e-53 181.8 0.0 3.3e-53 181.2 0.0 1.2 1 0 0 1 1 1 1 PAXNEB protein Peptidase_S26 PF10502.9 KNZ73492.1 - 4.1e-08 33.1 0.0 5.6e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 KNZ73492.1 - 7.4e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like TPR_1 PF00515.28 KNZ73493.1 - 2.7e-06 26.9 1.7 0.027 14.3 0.1 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73493.1 - 9.5e-05 22.2 1.3 0.83 9.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat RPN13_C PF16550.5 KNZ73493.1 - 0.0014 18.7 3.2 0.083 13.1 0.3 3.4 2 1 1 3 3 3 1 UCH-binding domain Csm2_III-A PF03750.13 KNZ73493.1 - 0.048 14.5 0.0 11 6.9 0.0 2.3 2 0 0 2 2 2 0 Csm2 Type III-A TPR_7 PF13176.6 KNZ73493.1 - 0.057 13.5 0.0 1.8 8.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C27 PF05407.12 KNZ73493.1 - 0.069 13.2 0.5 0.14 12.3 0.1 1.6 1 1 1 2 2 2 0 Rubella virus endopeptidase TPR_14 PF13428.6 KNZ73493.1 - 0.069 14.0 0.7 9.2 7.4 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4019 PF13211.6 KNZ73493.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) TPR_11 PF13414.6 KNZ73493.1 - 0.13 12.0 0.8 0.95 9.2 0.0 2.6 3 0 0 3 3 3 0 TPR repeat AlaDh_PNT_N PF05222.15 KNZ73494.1 - 4.2e-28 98.3 0.0 6e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KNZ73494.1 - 0.0027 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF5060 PF16586.5 KNZ73494.1 - 0.018 15.4 0.0 0.72 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) zf-Tim10_DDP PF02953.15 KNZ73497.1 - 3.4e-23 81.0 0.8 3.9e-23 80.9 0.8 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Acyltransferase PF01553.21 KNZ73498.1 - 7.5e-21 74.2 0.0 1.2e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KNZ73498.1 - 2.7e-09 37.0 0.0 5.2e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Hydrolase_4 PF12146.8 KNZ73500.1 - 9.3e-06 25.1 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ73500.1 - 0.0077 15.9 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chromo PF00385.24 KNZ73501.1 - 3e-07 30.2 4.4 6.4e-07 29.2 4.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3678 PF12435.8 KNZ73501.1 - 9 5.8 9.0 0.082 12.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Clat_adaptor_s PF01217.20 KNZ73502.1 - 1.6e-17 63.7 2.0 1.7e-17 63.6 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2672 PF10878.8 KNZ73502.1 - 0.068 13.1 2.1 0.082 12.9 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Glucosamine_iso PF01182.20 KNZ73503.1 - 3.7e-73 246.1 0.0 4.2e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ras PF00071.22 KNZ73504.1 - 7e-48 162.3 0.5 8.1e-48 162.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ73504.1 - 5.9e-22 78.1 0.0 1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ73504.1 - 9.5e-09 34.9 0.1 1.1e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ73504.1 - 6.5e-05 22.5 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KNZ73504.1 - 0.0024 17.3 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 KNZ73504.1 - 0.0093 15.8 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Glyco_hydro_75 PF07335.11 KNZ73504.1 - 0.061 13.6 0.1 0.078 13.3 0.1 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATG16 PF08614.11 KNZ73505.1 - 1.9e-54 184.9 21.5 2.7e-54 184.5 21.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 KNZ73505.1 - 0.00099 19.3 24.5 0.022 15.0 2.1 3.1 2 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KNZ73505.1 - 0.028 15.1 3.5 0.028 15.1 3.5 3.1 2 1 1 3 3 3 0 Initiation control protein YabA DUF2680 PF10925.8 KNZ73505.1 - 0.096 12.7 1.6 3.5 7.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2680) DUF4094 PF13334.6 KNZ73505.1 - 0.15 12.5 7.7 7.1 7.1 2.6 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) MPS2 PF17060.5 KNZ73505.1 - 0.51 9.5 8.8 4.1 6.6 5.5 2.3 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF1664 PF07889.12 KNZ73505.1 - 0.73 9.9 6.5 1.2 9.1 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 KNZ73505.1 - 0.77 10.2 16.3 0.65 10.4 5.8 2.2 1 1 1 2 2 2 0 Fez1 ZapB PF06005.12 KNZ73505.1 - 0.93 10.0 22.7 1.7 9.1 4.8 4.2 2 1 2 4 4 4 0 Cell division protein ZapB DUF5320 PF17253.2 KNZ73505.1 - 1.1 10.4 4.3 29 5.8 0.5 3.4 1 1 1 3 3 3 0 Family of unknown function (DUF5320) SlyX PF04102.12 KNZ73505.1 - 1.2 9.8 14.2 0.95 10.1 1.4 3.8 2 1 2 4 4 4 0 SlyX FlaC_arch PF05377.11 KNZ73505.1 - 1.6 9.2 6.0 9.7 6.7 0.1 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 KNZ73505.1 - 2.2 7.1 20.8 0.24 10.2 14.1 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KNZ73505.1 - 3.1 8.0 15.5 0.21 11.8 7.3 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF3574 PF12098.8 KNZ73505.1 - 4.2 7.2 5.5 8 6.3 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3574) MAD PF05557.13 KNZ73505.1 - 4.6 5.5 21.4 0.38 9.1 15.5 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein FlxA PF14282.6 KNZ73505.1 - 7.8 6.6 17.9 1 9.4 0.6 3.5 2 1 0 3 3 3 0 FlxA-like protein RRM_1 PF00076.22 KNZ73506.1 - 2.1e-51 171.6 0.0 2.3e-19 69.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNZ73506.1 - 7.6e-08 32.0 0.0 0.00053 19.6 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ73506.1 - 4.4e-06 26.5 0.0 0.0003 20.6 0.0 3.0 3 1 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KNZ73506.1 - 0.027 14.4 0.1 18 5.4 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KNZ73506.1 - 0.042 14.0 0.0 0.2 11.8 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif NupH_GANP PF16768.5 KNZ73506.1 - 0.092 12.4 8.1 0.15 11.8 8.1 1.3 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein Band_7 PF01145.25 KNZ73507.1 - 2.2e-25 89.7 3.3 4.4e-25 88.7 2.8 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KNZ73507.1 - 0.00055 19.1 4.0 0.00069 18.8 4.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial vATP-synt_E PF01991.18 KNZ73507.1 - 2.7 7.4 11.0 4 6.8 11.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Mitoc_mL59 PF18126.1 KNZ73508.1 - 8.6e-40 136.0 5.1 1.3e-39 135.5 5.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Asn_synthase PF00733.21 KNZ73509.1 - 1.4e-17 64.4 0.9 2.9e-06 27.2 0.1 3.3 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KNZ73509.1 - 1.3e-06 28.4 0.0 3.3e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.13 KNZ73509.1 - 0.00025 20.6 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KNZ73509.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase 6PGD PF00393.19 KNZ73510.1 - 5.6e-124 413.2 0.0 6.8e-124 412.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KNZ73510.1 - 1.1e-45 155.7 0.0 1.6e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Oxysterol_BP PF01237.18 KNZ73511.1 - 1e-112 376.7 0.0 2.9e-112 375.2 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 KNZ73511.1 - 1.8e-18 66.6 3.6 4.1e-17 62.2 0.0 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KNZ73511.1 - 1.1e-06 29.0 2.5 1.5e-06 28.7 0.0 2.5 3 0 0 3 3 3 1 PH domain TMF_TATA_bd PF12325.8 KNZ73511.1 - 0.037 14.2 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_3_C PF01915.22 KNZ73512.1 - 9.9e-52 175.9 0.1 1.8e-51 175.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ73512.1 - 4.2e-29 101.9 0.2 1.1e-19 70.9 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ73512.1 - 1.3e-19 70.1 0.0 2.5e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.18 KNZ73512.1 - 7.9e-06 25.7 2.6 1.7e-05 24.7 2.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Aconitase PF00330.20 KNZ73513.1 - 3.6e-128 428.4 0.0 5.8e-128 427.8 0.0 1.3 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KNZ73513.1 - 6.2e-07 29.8 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KNZ73513.1 - 0.086 11.5 0.0 2.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF521) MutS_V PF00488.21 KNZ73514.1 - 7.4e-70 234.8 0.0 1.3e-69 234.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KNZ73514.1 - 1.6e-37 129.6 1.0 3.5e-37 128.5 1.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KNZ73514.1 - 6.6e-24 84.3 0.0 1.8e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KNZ73514.1 - 8.2e-09 35.9 0.0 2.2e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_27 PF13514.6 KNZ73514.1 - 0.00017 21.2 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KNZ73514.1 - 0.13 12.7 0.3 0.39 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KNZ73514.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 KNZ73515.1 - 7.2e-106 353.6 0.6 9.2e-106 353.2 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KNZ73515.1 - 1.6e-06 28.1 0.0 5.8e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KNZ73515.1 - 0.00043 20.4 3.2 0.096 12.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KNZ73515.1 - 0.0074 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 KNZ73515.1 - 0.012 15.2 0.1 0.24 10.9 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KNZ73515.1 - 0.053 12.9 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KNZ73515.1 - 0.07 13.0 4.0 0.11 12.4 0.5 2.9 3 1 0 3 3 3 0 RsgA GTPase Roc PF08477.13 KNZ73515.1 - 0.078 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 KNZ73515.1 - 0.27 11.7 5.4 5.2 7.5 4.7 2.2 2 0 0 2 2 2 0 AAA domain MIT PF04212.18 KNZ73516.1 - 6.1e-05 23.0 0.4 0.00015 21.7 0.4 1.7 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF3543 PF12063.8 KNZ73516.1 - 0.12 11.8 1.9 0.19 11.1 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) SRA1 PF07304.11 KNZ73516.1 - 8.5 6.2 6.7 24 4.7 0.9 3.8 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) FA_hydroxylase PF04116.13 KNZ73517.1 - 1.3e-19 70.8 16.3 1.5e-19 70.6 16.3 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Helitron_like_N PF14214.6 KNZ73519.1 - 5.6e-25 88.7 0.0 6.8e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ73519.1 - 0.055 13.4 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Inovirus Gp2 PIF1 PF05970.14 KNZ73520.1 - 4.2e-19 68.9 0.0 4.6e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase MitMem_reg PF13012.6 KNZ73522.1 - 0.19 12.1 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ73523.1 - 1.6e-16 60.4 0.1 1.9e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ73523.1 - 0.00035 20.3 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ73523.1 - 0.0008 19.5 0.0 0.001 19.1 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ73523.1 - 0.0011 19.4 0.0 0.0015 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.8 KNZ73523.1 - 0.0054 15.6 0.0 0.007 15.3 0.0 1.1 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Zeta_toxin PF06414.12 KNZ73523.1 - 0.033 13.5 0.0 0.055 12.7 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KNZ73523.1 - 0.04 13.5 0.2 0.055 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 KNZ73523.1 - 0.073 13.0 0.2 0.11 12.4 0.2 1.2 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 KNZ73523.1 - 0.08 13.0 0.3 0.14 12.2 0.1 1.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 KNZ73523.1 - 0.08 12.7 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KNZ73523.1 - 0.084 13.3 0.6 1.9 8.9 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KNZ73523.1 - 0.095 13.1 0.0 0.21 12.0 0.0 1.6 2 0 0 2 2 2 0 RNA helicase Thymidylate_kin PF02223.17 KNZ73523.1 - 0.13 11.9 0.1 3.3 7.4 0.0 2.0 1 1 1 2 2 2 0 Thymidylate kinase AAA_22 PF13401.6 KNZ73523.1 - 0.14 12.5 0.1 0.23 11.8 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KNZ73523.1 - 0.16 12.3 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KNZ73524.1 - 1.2e-78 264.8 0.0 1.5e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KNZ73524.1 - 3.7e-06 25.2 0.0 4.8e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Helicase 4HPAD_g_N PF18671.1 KNZ73524.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal AAA_30 PF13604.6 KNZ73524.1 - 0.015 15.0 0.1 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 KNZ73524.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain F-box-like PF12937.7 KNZ73525.1 - 1.8e-07 30.9 0.4 4.1e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ73525.1 - 5.7e-06 26.1 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain Death_2 PF14786.6 KNZ73525.1 - 0.055 13.4 0.3 0.12 12.3 0.2 1.6 1 1 1 2 2 2 0 Tube Death domain Elongin_A PF06881.11 KNZ73525.1 - 0.1 13.1 0.1 0.17 12.5 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Aph-1 PF06105.12 KNZ73525.1 - 0.21 10.9 0.0 2.2 7.6 0.1 2.0 2 0 0 2 2 2 0 Aph-1 protein SURF4 PF02077.15 KNZ73526.1 - 5.4e-90 301.6 6.1 6.3e-90 301.4 6.1 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 KNZ73526.1 - 0.82 9.6 14.4 0.65 9.9 12.4 1.8 1 1 1 2 2 2 0 Nicotinamide mononucleotide transporter NUC153 PF08159.12 KNZ73527.1 - 3.8e-11 42.6 0.1 8.1e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KNZ73527.1 - 0.12 13.3 1.5 5.3 8.1 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1796 PF08795.10 KNZ73528.1 - 0.097 12.6 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) POT1PC PF16686.5 KNZ73529.1 - 0.046 13.6 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein AMP-binding PF00501.28 KNZ73531.1 - 7.5e-64 215.9 0.0 1.1e-63 215.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KNZ73531.1 - 1e-58 198.6 0.0 1.8e-58 197.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 KNZ73531.1 - 7.4e-14 51.3 0.0 2.5e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KNZ73531.1 - 1.1e-10 41.6 0.0 3e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KNZ73531.1 - 4.7e-06 26.2 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 KNZ73531.1 - 1.1e-05 26.3 0.0 3.6e-05 24.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HPIH PF13323.6 KNZ73532.1 - 0.031 14.2 0.7 0.054 13.3 0.7 1.4 1 0 0 1 1 1 0 N-terminal domain with HPIH motif HMG-CoA_red PF00368.18 KNZ73533.1 - 1.3e-48 165.9 6.8 1.7e-48 165.5 6.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Retrotran_gag_2 PF14223.6 KNZ73534.1 - 0.0079 15.9 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KNZ73534.1 - 0.021 14.6 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HMG-CoA_red PF00368.18 KNZ73536.1 - 6.2e-64 216.3 6.8 7.8e-64 216.0 6.8 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase PIF1 PF05970.14 KNZ73538.1 - 1.1e-28 100.5 0.1 1.6e-28 100.0 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ73538.1 - 0.0024 18.3 0.0 0.0033 17.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KNZ73538.1 - 0.0042 16.8 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ73538.1 - 0.0053 16.8 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2791 PF10923.8 KNZ73538.1 - 0.027 13.3 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.18 KNZ73538.1 - 0.03 14.1 0.1 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KNZ73538.1 - 0.11 12.0 0.2 0.18 11.4 0.2 1.5 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KNZ73539.1 - 3.1e-19 69.4 0.2 3.3e-19 69.3 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase Imm3 PF14425.6 KNZ73541.1 - 0.051 13.6 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 Immunity protein Imm3 AMP-binding PF00501.28 KNZ73543.1 - 7.1e-15 54.5 0.0 2.6e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme adh_short_C2 PF13561.6 KNZ73545.1 - 2e-51 174.8 0.1 2.5e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ73545.1 - 5.4e-38 130.4 0.2 7.9e-38 129.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ribosomal_L44 PF00935.19 KNZ73546.1 - 3e-37 127.0 12.0 4.9e-37 126.3 12.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 KNZ73546.1 - 0.68 10.3 3.6 0.2 12.0 0.6 1.6 2 0 0 2 2 2 0 Cathelicidin Acetyltransf_3 PF13302.7 KNZ73547.1 - 6.9e-06 26.8 0.0 1.6e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ73547.1 - 0.001 19.3 0.0 0.0018 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ73547.1 - 0.0086 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NARP1 PF12569.8 KNZ73548.1 - 5e-148 494.2 7.7 4e-146 487.9 0.8 3.0 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 KNZ73548.1 - 4e-15 56.2 3.8 0.68 10.6 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73548.1 - 8e-14 50.6 22.5 0.0079 16.2 0.0 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ73548.1 - 1.5e-09 37.8 7.1 0.057 14.3 0.0 8.8 7 2 3 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ73548.1 - 2.2e-09 37.7 14.8 0.11 13.0 1.0 7.8 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ73548.1 - 3.9e-09 35.9 12.7 0.0059 16.4 0.2 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ73548.1 - 9e-08 31.8 8.6 0.0064 16.6 0.0 6.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ73548.1 - 2e-07 31.1 3.2 3.2 8.0 0.0 6.5 6 1 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ73548.1 - 1.3e-06 28.6 3.3 3.4 7.9 0.0 6.3 6 1 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KNZ73548.1 - 6e-06 26.5 15.1 0.74 10.1 0.1 6.3 4 1 1 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ73548.1 - 7.8e-06 25.9 0.0 0.17 12.4 0.0 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ73548.1 - 2.5e-05 24.0 5.4 1.1 9.5 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ73548.1 - 5.8e-05 22.7 3.0 0.0041 16.8 0.4 4.5 5 0 0 5 5 5 1 TPR repeat TPR_4 PF07721.14 KNZ73548.1 - 0.00086 19.7 0.1 1.6 9.6 0.1 4.1 4 0 0 4 4 2 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 KNZ73548.1 - 0.39 10.8 1.6 5.3 7.2 0.1 3.4 4 0 0 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_6 PF13174.6 KNZ73548.1 - 1.4 9.7 10.3 2e+02 2.9 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.17 KNZ73548.1 - 3 8.3 7.5 8.5 6.8 2.1 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain HEAT_2 PF13646.6 KNZ73549.1 - 2.1e-06 28.0 3.7 5.7e-05 23.4 0.1 4.4 3 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 KNZ73549.1 - 2.4e-06 27.7 1.2 0.0084 16.2 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KNZ73549.1 - 0.00022 21.2 3.2 1.6 9.2 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 KNZ73549.1 - 0.0025 18.3 1.6 1 10.0 0.1 4.4 5 0 0 5 5 5 1 HEAT-like repeat Kdo_hydroxy PF11004.8 KNZ73549.1 - 0.091 12.0 0.1 0.93 8.7 0.0 2.4 3 0 0 3 3 3 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase SWIRM-assoc_2 PF16496.5 KNZ73549.1 - 0.92 8.3 7.1 1.6 7.5 7.1 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4218 PF13960.6 KNZ73550.1 - 0.061 12.9 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4218) F-box PF00646.33 KNZ73551.1 - 0.00032 20.5 0.1 0.00088 19.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ73551.1 - 0.0024 17.8 0.3 0.013 15.3 0.1 2.5 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 KNZ73551.1 - 1.9 8.4 5.8 0.63 9.9 0.1 2.8 3 0 0 3 3 3 0 F-box zf-C2H2 PF00096.26 KNZ73551.1 - 7 7.3 6.9 9.8 6.9 2.3 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type COesterase PF00135.28 KNZ73552.1 - 1.1e-54 186.2 0.0 5.6e-46 157.5 0.0 2.4 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ73552.1 - 0.0024 17.7 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 KNZ73552.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) SRP19 PF01922.17 KNZ73553.1 - 3.9e-26 91.8 0.0 1.1e-25 90.4 0.0 1.7 2 0 0 2 2 2 1 SRP19 protein JTB PF05439.12 KNZ73554.1 - 0.00036 20.5 0.1 0.00036 20.5 0.1 1.9 2 1 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) Glyco_hydro_18 PF00704.28 KNZ73555.1 - 2.9e-56 191.5 0.4 3.5e-56 191.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chromo PF00385.24 KNZ73556.1 - 0.0015 18.4 0.7 0.0033 17.3 0.7 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dak1 PF02733.17 KNZ73557.1 - 1.7e-88 296.5 0.2 4.2e-88 295.2 0.2 1.7 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KNZ73557.1 - 1.6e-44 151.8 0.1 2.8e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 DAK2 domain F-box PF00646.33 KNZ73557.1 - 0.00018 21.3 0.2 0.00065 19.5 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ73557.1 - 0.00019 21.2 0.1 0.00077 19.3 0.1 2.1 1 0 0 1 1 1 1 F-box-like SET PF00856.28 KNZ73559.1 - 7.4e-12 46.0 0.0 4e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 SET domain BCNT PF07572.12 KNZ73560.1 - 2.7e-20 72.2 0.0 5.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development T3SS_needle_reg PF09025.10 KNZ73560.1 - 0.06 13.3 0.2 0.093 12.7 0.2 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator Bin3 PF06859.12 KNZ73562.1 - 7.1e-37 126.4 0.0 1.3e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 KNZ73562.1 - 2.5e-11 44.1 0.0 2.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ73562.1 - 7.3e-11 42.2 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ73562.1 - 6e-10 39.7 0.0 0.00021 21.9 0.0 2.5 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73562.1 - 5.9e-09 35.9 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73562.1 - 7.1e-07 29.9 0.0 0.0032 18.2 0.0 2.4 3 0 0 3 3 2 2 Methyltransferase domain PrmA PF06325.13 KNZ73562.1 - 0.00073 19.0 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 KNZ73562.1 - 0.0069 15.3 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) POR PF01558.18 KNZ73562.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase CMAS PF02353.20 KNZ73562.1 - 0.017 14.4 0.1 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KNZ73562.1 - 0.018 14.4 0.0 5.4 6.3 0.0 2.5 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 KNZ73562.1 - 0.02 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 KNZ73562.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 KNZ73562.1 - 0.2 11.1 0.0 12 5.3 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase domain UCH PF00443.29 KNZ73563.1 - 1e-39 136.6 0.0 1.6e-39 136.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ73563.1 - 1.2e-11 44.8 0.0 0.00014 21.6 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_1 PF00232.18 KNZ73565.1 - 6e-141 469.9 0.5 7.1e-140 466.4 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 BH4 PF02180.17 KNZ73565.1 - 0.045 13.6 0.5 0.13 12.1 0.5 1.7 1 0 0 1 1 1 0 Bcl-2 homology region 4 Asp_protease_2 PF13650.6 KNZ73567.1 - 0.15 12.7 0.0 2.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease PUF PF00806.19 KNZ73568.1 - 2.1e-26 90.1 0.1 2.1e-07 30.2 0.0 6.0 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DCP1 PF06058.13 KNZ73569.1 - 1.1e-23 83.4 0.0 3.8e-23 81.7 0.0 2.0 1 1 0 1 1 1 1 Dcp1-like decapping family ECF_trnsprt PF12822.7 KNZ73569.1 - 0.54 10.3 13.8 1.1 9.4 13.8 1.4 1 0 0 1 1 1 0 ECF transporter, substrate-specific component DUF1768 PF08719.11 KNZ73570.1 - 6e-32 111.1 0.1 7e-32 110.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) ORC2 PF04084.14 KNZ73571.1 - 1.9e-95 319.6 0.0 2.4e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 MatE PF01554.18 KNZ73573.1 - 5.2e-55 185.5 25.4 2e-28 99.0 6.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KNZ73573.1 - 0.00029 20.9 13.9 0.00029 20.9 13.9 3.6 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain UCR_6-4kD PF08997.10 KNZ73573.1 - 0.055 13.4 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein adh_short PF00106.25 KNZ73574.1 - 3.6e-37 127.7 0.0 4.8e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ73574.1 - 3.3e-27 95.6 0.0 4.7e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ73574.1 - 2.2e-07 30.9 0.0 6.1e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ73574.1 - 9.6e-07 28.5 0.0 1.9e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ73574.1 - 2.5e-05 24.3 0.0 4.5e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KNZ73574.1 - 0.00057 19.1 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KNZ73574.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Steroid_dh PF02544.16 KNZ73575.1 - 4.4e-34 117.6 2.3 4.4e-34 117.6 2.3 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 KNZ73575.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family APH PF01636.23 KNZ73577.1 - 1.3e-09 38.4 1.7 2.2e-09 37.6 1.7 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ73577.1 - 0.00038 20.1 0.0 0.00069 19.3 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase PRP3 PF08572.10 KNZ73578.1 - 5.5e-69 232.3 4.6 9.9e-69 231.5 4.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KNZ73578.1 - 1.4e-43 148.5 1.2 3.5e-43 147.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosomal_L16 PF00252.18 KNZ73579.1 - 2.1e-38 131.3 0.4 2.6e-38 131.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Presenilin PF01080.17 KNZ73580.1 - 0.19 10.5 0.9 0.19 10.5 0.9 1.1 1 0 0 1 1 1 0 Presenilin CI-B14_5a PF07347.12 KNZ73580.1 - 0.39 10.6 6.4 0.93 9.4 6.4 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) VirC2 PF07181.11 KNZ73580.1 - 0.79 9.2 4.5 1.2 8.6 4.5 1.2 1 0 0 1 1 1 0 VirC2 protein DUF4834 PF16118.5 KNZ73580.1 - 1.5 9.8 7.0 2.8 9.0 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Atg14 PF10186.9 KNZ73580.1 - 4.8 6.2 9.0 8.6 5.3 9.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Acetyltransf_8 PF13523.6 KNZ73581.1 - 8.1e-38 129.4 0.1 1.1e-37 129.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNZ73581.1 - 0.014 16.1 0.1 0.15 12.7 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.15 KNZ73582.1 - 5.8e-35 120.9 35.7 1.3e-33 116.4 35.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HMW1C_N PF18071.1 KNZ73584.1 - 0.033 14.0 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 HMW1C N-terminal ThylakoidFormat PF11264.8 KNZ73585.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein zinc_ribbon_11 PF11682.8 KNZ73588.1 - 0.05 13.6 0.3 0.064 13.3 0.3 1.3 1 0 0 1 1 1 0 Probable zinc-ribbon PIF1 PF05970.14 KNZ73590.1 - 1.8e-29 103.1 0.0 2e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ73590.1 - 0.0064 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UvrD_C_2 PF13538.6 KNZ73590.1 - 0.037 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MLVIN_C PF18697.1 KNZ73591.1 - 0.14 12.3 0.1 0.22 11.6 0.0 1.5 1 1 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Aldedh PF00171.22 KNZ73595.1 - 2.1e-176 587.0 1.2 2.3e-176 586.8 1.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KNZ73595.1 - 0.0046 16.1 0.1 0.055 12.5 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Alpha-L-AF_C PF06964.12 KNZ73596.1 - 5.4e-28 98.2 0.0 1.4e-27 96.9 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_44 PF12891.7 KNZ73596.1 - 0.0025 17.8 0.0 0.0058 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 44 GH3 PF03321.13 KNZ73596.1 - 0.052 12.4 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter UQ_con PF00179.26 KNZ73597.1 - 7.8e-41 139.0 0.0 9e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNZ73597.1 - 0.0024 17.6 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KNZ73597.1 - 0.0097 15.8 0.1 0.018 14.9 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KNZ73597.1 - 0.085 13.1 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain SH3_9 PF14604.6 KNZ73599.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ73599.1 - 0.07 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 SH3 domain zf-RVT PF13966.6 KNZ73601.1 - 0.0032 18.1 1.2 0.0047 17.6 1.2 1.5 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Sulfotransfer_4 PF17784.1 KNZ73601.1 - 0.037 13.8 0.3 0.045 13.6 0.3 1.1 1 0 0 1 1 1 0 Sulfotransferase domain DUF677 PF05055.12 KNZ73601.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) zf-TFIIB PF13453.6 KNZ73601.1 - 0.19 11.1 1.0 0.3 10.4 0.1 1.8 2 0 0 2 2 2 0 Transcription factor zinc-finger GCIP PF13324.6 KNZ73602.1 - 0.066 12.8 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Glyco_transf_20 PF00982.21 KNZ73603.1 - 5.6e-131 437.5 0.0 7.3e-131 437.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KNZ73603.1 - 8.2e-18 64.4 0.0 3.4e-16 59.1 0.0 2.9 3 1 0 3 3 3 1 Trehalose-phosphatase Herpes_capsid PF06112.11 KNZ73603.1 - 3.2 7.8 5.5 8.4 6.4 5.5 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Metallophos PF00149.28 KNZ73604.1 - 4.1e-35 122.1 0.0 5.3e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KNZ73604.1 - 0.007 16.0 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 KNZ73604.1 - 0.035 14.6 0.0 0.082 13.4 0.0 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KNZ73604.1 - 0.15 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_18 PF00704.28 KNZ73605.1 - 5.2e-26 92.1 1.7 2.2e-25 90.0 1.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF563 PF04577.14 KNZ73606.1 - 2.2e-19 70.4 0.3 6.3e-18 65.7 0.0 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF563) Sigma70_r2 PF04542.14 KNZ73607.1 - 0.11 12.2 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 region 2 Glyco_hydro_10 PF00331.20 KNZ73608.1 - 5.3e-69 232.8 0.0 6e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 ATG13 PF10033.9 KNZ73609.1 - 1.3e-31 110.1 0.0 2.9e-31 109.0 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 HsbA PF12296.8 KNZ73614.1 - 9.3e-05 22.8 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Metallophos PF00149.28 KNZ73615.1 - 9.3e-06 26.3 0.2 2.7e-05 24.8 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cutinase PF01083.22 KNZ73617.1 - 1.8e-42 145.3 1.6 2.1e-42 145.1 1.6 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KNZ73617.1 - 7.8e-05 22.3 0.3 0.00012 21.7 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 KNZ73617.1 - 0.00048 20.8 0.3 0.00053 20.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BTB PF00651.31 KNZ73618.1 - 0.002 18.3 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Mob1_phocein PF03637.17 KNZ73619.1 - 1.9e-16 60.6 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Mob1/phocein family NusA_N PF08529.11 KNZ73619.1 - 3.5 8.0 8.6 1.1 9.6 1.8 2.3 2 0 0 2 2 2 0 NusA N-terminal domain AA_permease_2 PF13520.6 KNZ73622.1 - 2.4e-73 247.4 28.4 3e-73 247.1 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ73622.1 - 1.4e-18 66.8 24.6 1.8e-18 66.4 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3995 PF13160.6 KNZ73622.1 - 0.8 10.1 12.8 7.9 6.9 1.8 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3995) Pkinase_Tyr PF07714.17 KNZ73623.1 - 1.4e-31 109.8 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ73623.1 - 3.7e-30 105.2 0.0 4.4e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ73623.1 - 0.00089 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNZ73623.1 - 0.013 14.3 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KNZ73623.1 - 0.04 13.8 0.2 0.074 13.0 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family C2 PF00168.30 KNZ73624.1 - 1.8e-24 86.0 0.0 9.1e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Cul7 PF11515.8 KNZ73624.1 - 0.038 14.3 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 SMP_LBD PF17047.5 KNZ73624.1 - 0.095 12.2 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain FHA PF00498.26 KNZ73625.1 - 1.9e-07 31.3 0.0 3.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain DUF2470 PF10615.9 KNZ73626.1 - 8.1e-16 58.4 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 KNZ73626.1 - 1.5e-07 31.6 2.3 2.5e-07 30.9 2.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4499) DNA_binding_1 PF01035.20 KNZ73627.1 - 3.8e-23 81.4 0.1 5.3e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Cu-oxidase PF00394.22 KNZ73628.1 - 1.5e-42 145.4 0.2 3.3e-40 137.8 0.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ73628.1 - 6.8e-35 119.8 6.5 3.8e-33 114.1 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ73628.1 - 1.2e-28 99.6 5.8 2.9e-27 95.1 1.2 3.0 3 0 0 3 3 3 2 Multicopper oxidase FMN_red PF03358.15 KNZ73630.1 - 2.5e-11 43.6 0.0 2.9e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KNZ73630.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KNZ73630.1 - 0.0032 17.7 0.0 0.14 12.4 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin PhoD PF09423.10 KNZ73631.1 - 3.8e-100 335.3 0.2 4.6e-100 335.0 0.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KNZ73631.1 - 1.3e-21 76.9 0.0 2.7e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KNZ73631.1 - 0.0012 19.4 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain LRR_8 PF13855.6 KNZ73632.1 - 0.84 9.4 8.8 0.94 9.3 0.1 4.0 5 0 0 5 5 5 0 Leucine rich repeat RRM_1 PF00076.22 KNZ73633.1 - 9.8e-12 44.5 0.0 1.5e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KNZ73633.1 - 1.6e-07 31.7 0.1 2.9e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 PHP PF02811.19 KNZ73634.1 - 6.5e-14 52.6 0.1 1e-13 51.9 0.1 1.3 1 0 0 1 1 1 1 PHP domain WD40 PF00400.32 KNZ73635.1 - 5.9e-30 102.9 29.0 0.0002 22.1 0.4 11.3 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ73635.1 - 2.6e-18 66.1 2.5 2.6e-08 34.0 0.0 6.7 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ73635.1 - 2.6e-05 24.2 0.8 2.4 8.0 0.1 4.6 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.15 KNZ73635.1 - 0.0013 18.1 0.0 0.99 8.7 0.0 2.4 2 0 0 2 2 2 2 CPSF A subunit region PD40 PF07676.12 KNZ73635.1 - 0.0014 18.5 1.1 2.9 8.0 0.1 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KNZ73635.1 - 0.0035 15.4 0.2 0.056 11.4 0.1 2.1 2 0 0 2 2 2 1 IKI3 family Nbas_N PF15492.6 KNZ73635.1 - 0.0078 15.6 0.6 0.57 9.5 0.0 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 KNZ73635.1 - 0.0086 15.1 1.5 4.2 6.2 0.0 4.5 4 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KNZ73635.1 - 0.012 14.9 0.1 0.09 12.0 0.0 2.3 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4394 PF14339.6 KNZ73635.1 - 0.058 12.8 0.2 0.21 10.9 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4394) TFIIIC_delta PF12657.7 KNZ73635.1 - 0.06 13.3 2.3 7 6.5 0.1 2.8 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term SUKH-4 PF14435.6 KNZ73635.1 - 0.081 13.0 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 SUKH-4 immunity protein Exo_endo_phos_2 PF14529.6 KNZ73638.1 - 1.7e-07 31.1 0.6 4.6e-07 29.7 0.6 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AIP3 PF03915.13 KNZ73640.1 - 0.038 13.1 13.7 0.057 12.5 13.7 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 BCDHK_Adom3 PF10436.9 KNZ73640.1 - 0.63 9.9 6.7 3.6 7.4 6.7 2.0 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Tup_N PF08581.10 KNZ73640.1 - 5.1 7.5 10.7 1.9 8.9 5.8 2.4 2 0 0 2 2 2 0 Tup N-terminal Aldedh PF00171.22 KNZ73641.1 - 8.5e-08 31.1 0.0 9.8e-08 30.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3558 PF12079.8 KNZ73641.1 - 0.0051 16.8 0.1 0.0058 16.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3558) Ribosomal_L14e PF01929.17 KNZ73641.1 - 0.035 14.6 0.2 11 6.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L14 CMAS PF02353.20 KNZ73641.1 - 0.19 11.0 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AMP-binding PF00501.28 KNZ73642.1 - 1.6e-26 92.9 0.1 3.2e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KNZ73642.1 - 1.4e-25 89.9 0.0 2.2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KNZ73642.1 - 3.5e-07 29.9 0.0 1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ73642.1 - 0.13 12.1 0.0 6.9 6.5 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Exo_endo_phos_2 PF14529.6 KNZ73644.1 - 4.2e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KNZ73644.1 - 9.3e-05 22.6 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 RNase H Ydr279_N PF17745.1 KNZ73644.1 - 0.074 13.3 0.3 0.28 11.5 0.1 1.9 1 1 1 2 2 2 0 Ydr279p protein triple barrel domain RGM_C PF06534.13 KNZ73644.1 - 0.28 10.7 0.1 0.28 10.7 0.1 1.6 2 0 0 2 2 2 0 Repulsive guidance molecule (RGM) C-terminus TauD PF02668.16 KNZ73645.1 - 1.8e-50 172.2 0.3 2.5e-50 171.7 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KNZ73645.1 - 9.7e-10 39.0 0.0 2.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KNZ73645.1 - 0.0021 17.2 0.0 0.083 12.0 0.0 2.0 2 0 0 2 2 2 2 CsiD MaoC_dehydratas PF01575.19 KNZ73646.1 - 1.7e-26 92.2 0.0 4.6e-26 90.8 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 KNZ73646.1 - 2.5e-06 27.7 0.0 0.00019 21.6 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase NAD_binding_11 PF14833.6 KNZ73647.1 - 3.3e-29 101.6 0.4 6.9e-29 100.6 0.4 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HAD_2 PF13419.6 KNZ73647.1 - 5e-17 62.5 0.0 8.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ73647.1 - 3.4e-12 47.1 0.0 4.1e-11 43.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KNZ73647.1 - 2.9e-05 24.6 0.0 5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Zot PF05707.12 KNZ73647.1 - 0.027 14.1 0.0 0.086 12.5 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Hydrolase_6 PF13344.6 KNZ73647.1 - 0.086 13.0 0.0 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 KNZ73647.1 - 0.19 11.3 0.0 11 5.5 0.0 2.3 3 0 0 3 3 3 0 HAD superfamily, subfamily IIIB (Acid phosphatase) VWA_2 PF13519.6 KNZ73648.1 - 9.2e-25 87.4 2.6 3.2e-24 85.6 0.1 2.7 2 1 1 3 3 3 1 von Willebrand factor type A domain UIM PF02809.20 KNZ73648.1 - 8e-07 28.6 21.8 0.0035 17.2 2.3 3.9 3 1 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 KNZ73648.1 - 1.1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like p450 PF00067.22 KNZ73649.1 - 3.4e-72 243.7 0.0 6.8e-72 242.7 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Actin PF00022.19 KNZ73650.1 - 8.5e-143 475.8 0.0 5.2e-142 473.2 0.0 1.8 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 KNZ73650.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase EMG1 PF03587.14 KNZ73651.1 - 3.8e-75 251.8 0.0 4.6e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase ETF PF01012.21 KNZ73652.1 - 1.3e-34 119.6 0.6 2.4e-34 118.8 0.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KNZ73652.1 - 2.1e-31 107.8 0.9 2.1e-31 107.8 0.9 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain EMC1_C PF07774.13 KNZ73653.1 - 1.4e-71 240.6 0.1 2.5e-71 239.8 0.1 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 KNZ73653.1 - 9.6e-15 54.8 0.6 2.3e-10 40.4 0.2 3.4 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 KNZ73653.1 - 3e-08 33.2 0.2 0.0048 16.8 0.1 3.1 2 0 0 2 2 2 2 PQQ enzyme repeat FolB PF02152.18 KNZ73654.1 - 5.1e-37 126.8 0.0 2.2e-22 79.7 0.0 2.0 2 0 0 2 2 2 2 Dihydroneopterin aldolase Thioredoxin PF00085.20 KNZ73656.1 - 3.9e-50 168.1 0.0 4.3e-28 97.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 KNZ73656.1 - 3.6e-09 36.8 0.3 0.00035 20.9 0.0 4.5 4 2 1 5 5 5 2 Thioredoxin-like Thioredoxin_6 PF13848.6 KNZ73656.1 - 6e-08 32.8 0.0 0.00029 20.8 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KNZ73656.1 - 5.4e-06 26.4 0.0 0.0053 16.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_2 PF13098.6 KNZ73656.1 - 7.9e-05 23.1 0.2 0.029 14.8 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KNZ73656.1 - 0.00064 19.2 0.1 1.1 8.5 0.0 2.8 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_4 PF13462.6 KNZ73656.1 - 0.00094 19.4 0.7 0.045 13.9 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_7 PF13899.6 KNZ73656.1 - 0.002 18.2 0.8 0.012 15.7 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin-like TraF PF13728.6 KNZ73656.1 - 0.0021 17.9 0.1 0.32 10.8 0.0 2.3 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 KNZ73656.1 - 0.85 9.9 2.9 17 5.7 0.1 2.8 2 0 0 2 2 2 0 Glutaredoxin CGI-121 PF08617.10 KNZ73657.1 - 3.6e-33 115.0 0.0 4.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 PPR_2 PF13041.6 KNZ73658.1 - 2.6e-43 146.0 8.6 7.9e-07 29.2 0.0 12.8 10 2 4 14 14 14 10 PPR repeat family PPR PF01535.20 KNZ73658.1 - 2.1e-37 124.8 12.8 2e-05 24.5 0.0 15.2 18 0 0 18 18 18 6 PPR repeat PPR_3 PF13812.6 KNZ73658.1 - 1.7e-28 98.4 3.8 6.9e-08 32.4 0.0 11.2 10 3 3 13 13 13 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 KNZ73658.1 - 2.3e-23 81.6 0.0 1.9e-05 24.2 0.0 9.5 9 0 0 9 9 9 6 PPR repeat PPR_long PF17177.4 KNZ73658.1 - 3.3e-13 49.5 6.0 1.3e-09 37.7 0.7 5.0 3 2 3 6 6 6 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KNZ73658.1 - 3.3e-06 27.5 2.1 7.8 7.6 0.0 8.3 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ73658.1 - 7.1e-05 23.2 1.0 6 7.5 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat SPOB_a PF14689.6 KNZ73658.1 - 0.059 13.1 0.0 1.8 8.3 0.0 3.1 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Coilin_N PF15862.5 KNZ73659.1 - 1.2e-05 25.1 3.7 1.2e-05 25.1 3.7 2.8 3 0 0 3 3 3 1 Coilin N-terminus DUF1338 PF07063.13 KNZ73659.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) SR-25 PF10500.9 KNZ73659.1 - 0.41 10.2 52.5 1.2 8.7 25.8 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 KNZ73659.1 - 0.72 9.8 23.4 0.27 11.2 17.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Sec63 PF02889.16 KNZ73660.1 - 6e-18 64.9 0.0 1.6e-17 63.5 0.0 1.7 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 KNZ73660.1 - 3.2e-14 52.8 0.3 7.2e-14 51.7 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain UPRTase PF14681.6 KNZ73661.1 - 2.9e-74 249.0 0.0 3.7e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KNZ73661.1 - 0.0032 17.0 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2067 PF09840.9 KNZ73662.1 - 0.013 15.0 0.0 0.048 13.2 0.0 1.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) Rx_N PF18052.1 KNZ73662.1 - 0.036 14.3 0.7 0.1 12.9 0.7 1.7 1 0 0 1 1 1 0 Rx N-terminal domain WD40 PF00400.32 KNZ73663.1 - 2.2e-16 59.9 12.3 2e-06 28.4 1.4 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ73663.1 - 9.3e-09 35.5 0.0 0.053 13.8 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ73663.1 - 5.8e-05 23.0 0.1 0.008 16.1 0.0 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PTPRCAP PF15713.5 KNZ73663.1 - 0.026 14.8 3.2 0.069 13.4 3.2 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated MMS1_N PF10433.9 KNZ73663.1 - 0.098 11.3 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.6 KNZ73663.1 - 0.12 12.3 0.0 1 9.3 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Tti2 PF10521.9 KNZ73664.1 - 1.3e-43 149.6 0.0 2.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Tti2 family EF-hand_1 PF00036.32 KNZ73666.1 - 2e-28 95.8 10.6 2.5e-07 29.8 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KNZ73666.1 - 7e-25 87.3 5.3 5.2e-15 55.6 1.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KNZ73666.1 - 6.8e-23 78.6 6.8 1.3e-05 24.8 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KNZ73666.1 - 5e-18 63.7 13.1 1.1e-05 24.7 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KNZ73666.1 - 2.3e-12 46.6 13.1 0.00099 18.9 0.4 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 KNZ73666.1 - 8.8e-06 25.6 6.1 0.0047 16.9 0.6 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KNZ73666.1 - 3e-05 24.3 0.0 0.081 13.2 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KNZ73666.1 - 0.0019 18.5 0.2 0.72 10.2 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain Homeodomain PF00046.29 KNZ73666.1 - 0.16 11.8 0.3 0.45 10.4 0.1 1.8 2 0 0 2 2 2 0 Homeodomain Dockerin_1 PF00404.18 KNZ73666.1 - 0.19 12.0 2.1 0.83 9.9 1.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain TrmE_N PF10396.9 KNZ73667.1 - 6.4e-35 119.9 0.0 1.3e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 KNZ73667.1 - 9.1e-35 120.7 0.1 1.2e-34 120.3 0.1 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 KNZ73667.1 - 9.6e-16 57.9 0.0 2.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ73667.1 - 0.0034 16.9 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KNZ73667.1 - 0.0098 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 KNZ73667.1 - 0.079 13.3 0.0 0.17 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 KNZ73667.1 - 0.13 12.2 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KNZ73667.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.32 KNZ73668.1 - 4.4e-09 36.8 11.5 0.0029 18.4 0.5 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat DUF4731 PF15875.5 KNZ73669.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) MARVEL PF01284.23 KNZ73670.1 - 6.3 6.8 20.8 9.6 6.2 20.8 1.3 1 0 0 1 1 1 0 Membrane-associating domain tRNA-synt_1g PF09334.11 KNZ73671.1 - 2.8e-76 256.8 0.0 4.4e-74 249.6 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KNZ73671.1 - 1.1e-18 66.9 0.0 2.5e-12 45.9 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KNZ73671.1 - 3.3e-09 36.5 0.0 4.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KNZ73671.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA SCO1-SenC PF02630.14 KNZ73672.1 - 3.1e-44 150.2 0.0 5e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KNZ73672.1 - 0.0019 18.1 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KNZ73672.1 - 0.0033 17.7 0.0 0.0053 17.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like MBOAT PF03062.19 KNZ73673.1 - 2.6e-45 155.3 4.1 2.6e-45 155.3 4.1 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abhydrolase_6 PF12697.7 KNZ73674.1 - 3.2e-13 50.8 0.5 1.7e-11 45.2 0.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ73674.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold GN3L_Grn1 PF08701.11 KNZ73675.1 - 7.5e-24 83.6 17.8 2e-23 82.2 17.8 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KNZ73675.1 - 4.2e-14 52.6 0.1 2.7e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ73675.1 - 6.3e-08 32.7 0.5 5.9e-06 26.3 0.3 2.3 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KNZ73675.1 - 2e-07 30.5 0.1 3.4e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KNZ73675.1 - 0.00013 22.0 5.8 0.00036 20.6 0.8 3.0 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.18 KNZ73675.1 - 0.00053 19.5 0.0 0.004 16.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.18 KNZ73675.1 - 0.00082 18.7 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 KNZ73675.1 - 0.001 18.7 0.4 4.1 6.9 0.0 3.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 KNZ73675.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fungal_lectin PF07938.12 KNZ73675.1 - 0.053 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal fucose-specific lectin GBP PF02263.19 KNZ73675.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.27 KNZ73675.1 - 2 8.9 4.6 0.55 10.7 0.1 2.2 3 0 0 3 3 3 0 ABC transporter F-box-like PF12937.7 KNZ73676.1 - 2.6e-05 24.0 3.0 7.2e-05 22.6 0.2 3.0 3 0 0 3 3 3 1 F-box-like PUF PF00806.19 KNZ73677.1 - 3.7e-15 54.7 0.0 0.0029 17.2 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Ribosomal_L18 PF17135.4 KNZ73678.1 - 2e-79 265.3 0.4 2e-79 265.3 0.4 3.3 5 0 0 5 5 5 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KNZ73678.1 - 0.0015 19.2 0.0 0.026 15.2 0.0 2.7 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A zf-RING_11 PF17123.5 KNZ73678.1 - 0.03 14.1 0.3 0.064 13.0 0.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger ZNRF_3_ecto PF18212.1 KNZ73678.1 - 0.071 13.1 0.0 19 5.3 0.0 2.7 2 0 0 2 2 2 0 ZNRF-3 Ectodomain RRM_1 PF00076.22 KNZ73679.1 - 7.2e-17 61.0 0.0 9.7e-17 60.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNZ73679.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.21 KNZ73680.1 - 3.5e-15 56.0 31.0 3e-10 40.2 7.1 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-CCCH PF00642.24 KNZ73680.1 - 1.5e-13 50.3 12.0 5.8e-07 29.3 3.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KNZ73680.1 - 9.3e-12 44.5 14.7 2.1e-07 30.6 3.7 2.8 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KNZ73680.1 - 1.7e-10 40.6 20.0 1.7e-05 24.7 4.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-RING_UBOX PF13445.6 KNZ73680.1 - 1.1e-06 28.5 5.5 1.1e-06 28.5 5.5 3.0 3 1 0 3 3 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNZ73680.1 - 1.9e-05 24.4 2.3 1.9e-05 24.4 2.3 3.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ73680.1 - 2.6e-05 24.0 5.7 2.6e-05 24.0 5.7 4.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ73680.1 - 3.7e-05 24.0 4.2 3.7e-05 24.0 4.2 4.5 3 1 1 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KNZ73680.1 - 0.00021 21.1 2.8 0.00021 21.1 2.8 4.2 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KNZ73680.1 - 0.00026 20.8 0.0 0.13 12.1 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_4 PF15227.6 KNZ73680.1 - 0.00034 20.7 5.4 0.00034 20.7 5.4 3.7 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KNZ73680.1 - 0.0025 17.8 5.9 0.0025 17.8 5.9 3.8 3 2 1 4 4 2 1 zinc-RING finger domain Torus PF16131.5 KNZ73680.1 - 0.23 12.2 0.1 0.23 12.2 0.1 3.8 4 0 0 4 4 3 0 Torus domain zf-CCCH_2 PF14608.6 KNZ73680.1 - 0.82 10.2 28.3 0.34 11.4 4.5 4.2 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger DUF3584 PF12128.8 KNZ73681.1 - 0.53 7.7 12.0 0.76 7.2 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MS_channel PF00924.18 KNZ73682.1 - 2.1e-06 27.4 0.2 4.2e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel FDF PF09532.10 KNZ73682.1 - 0.016 16.1 0.5 0.032 15.1 0.5 1.4 1 0 0 1 1 1 0 FDF domain Sulf_transp PF04143.14 KNZ73683.1 - 0.085 12.4 3.4 0.11 12.1 1.9 1.9 1 1 1 2 2 2 0 Sulphur transport PTCRA PF15028.6 KNZ73683.1 - 0.18 11.5 0.3 0.36 10.5 0.3 1.4 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Ribosomal_L12 PF00542.19 KNZ73684.1 - 5.2e-23 81.2 2.8 3e-20 72.3 2.8 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KNZ73684.1 - 2.3e-15 56.0 4.1 2e-14 53.0 2.3 2.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Not3 PF04065.15 KNZ73685.1 - 6.2e-76 254.8 18.2 1e-75 254.1 18.2 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KNZ73685.1 - 6.9e-44 149.1 8.7 2.7e-43 147.2 8.7 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF3138 PF11336.8 KNZ73685.1 - 0.19 10.3 0.7 0.45 9.1 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF812 PF05667.11 KNZ73685.1 - 0.19 10.6 15.4 0.3 9.9 15.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CLZ PF16526.5 KNZ73685.1 - 2.7 8.4 9.9 0.74 10.2 3.7 3.0 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF641 PF04859.12 KNZ73685.1 - 6.4 7.1 15.3 3.1 8.2 6.5 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) SH3_1 PF00018.28 KNZ73686.1 - 2.9e-23 81.2 0.0 1.3e-10 40.7 0.0 3.2 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 KNZ73686.1 - 1.7e-18 66.2 0.2 1.3e-08 34.6 0.0 3.5 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 KNZ73686.1 - 2e-16 59.4 0.0 1.2e-09 37.7 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 KNZ73686.1 - 6.1e-08 32.6 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 PX domain NDUFA12 PF05071.16 KNZ73687.1 - 9e-30 103.4 4.7 1.4e-29 102.8 4.7 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DAO PF01266.24 KNZ73688.1 - 1.6e-52 179.2 0.0 1.8e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ73688.1 - 0.00054 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ73688.1 - 0.011 14.8 0.0 0.067 12.2 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 KNZ73688.1 - 0.057 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox PF00070.27 KNZ73688.1 - 0.076 13.6 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNZ73688.1 - 0.084 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPR_1 PF00515.28 KNZ73689.1 - 3.4e-10 39.3 10.2 0.01 15.6 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73689.1 - 7.4e-06 25.7 11.2 0.079 13.1 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ73689.1 - 0.00014 22.4 0.1 0.049 14.5 0.0 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ73689.1 - 0.00063 19.8 2.0 0.078 13.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KNZ73689.1 - 0.0019 18.2 0.5 0.014 15.5 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 KNZ73689.1 - 0.0032 17.1 0.7 0.074 12.7 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.6 KNZ73689.1 - 0.007 16.3 0.2 8.2 6.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ73689.1 - 0.027 15.0 2.5 0.72 10.4 0.1 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ73689.1 - 0.051 13.9 0.8 12 6.2 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF5484 PF17583.2 KNZ73689.1 - 0.18 11.5 0.1 0.42 10.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5484) Ribosomal_S7e PF01251.18 KNZ73690.1 - 1.7e-86 288.7 2.4 2e-86 288.4 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ras PF00071.22 KNZ73691.1 - 7.8e-46 155.6 0.0 8.5e-42 142.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KNZ73691.1 - 6e-33 113.6 0.0 8.6e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ73691.1 - 1.1e-10 41.2 0.0 5e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ73691.1 - 2e-06 27.9 0.0 3.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KNZ73691.1 - 0.00016 21.4 0.1 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KNZ73691.1 - 0.00019 21.7 0.1 0.0026 18.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KNZ73691.1 - 0.00024 20.6 0.0 0.00042 19.7 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KNZ73691.1 - 0.00028 20.4 0.2 0.00068 19.1 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KNZ73691.1 - 0.00083 19.3 0.2 0.0056 16.6 0.0 2.3 2 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 KNZ73691.1 - 0.0013 19.1 0.0 0.003 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KNZ73691.1 - 0.025 14.3 0.2 0.054 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KNZ73691.1 - 0.076 12.5 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 KNZ73691.1 - 0.091 12.2 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 KNZ73691.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 KNZ73691.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 KNZ73691.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KNZ73691.1 - 0.19 11.0 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Septin AMMECR1 PF01871.17 KNZ73692.1 - 7.9e-46 155.7 0.0 1.4e-45 154.9 0.0 1.3 1 1 0 1 1 1 1 AMMECR1 Tannase PF07519.11 KNZ73695.1 - 3.6e-88 296.5 0.0 4.5e-88 296.2 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KNZ73695.1 - 0.0038 16.9 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ73695.1 - 0.0041 16.4 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chs7 PF12271.8 KNZ73696.1 - 9.2e-73 245.1 5.7 1.1e-72 244.9 5.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone BTB PF00651.31 KNZ73697.1 - 7e-06 26.2 0.1 1.4e-05 25.3 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain Gal4_dimer PF03902.13 KNZ73697.1 - 0.13 12.4 1.8 0.48 10.6 0.1 2.4 3 0 0 3 3 3 0 Gal4-like dimerisation domain Ank_5 PF13857.6 KNZ73698.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Glyco_hydro_11 PF00457.17 KNZ73699.1 - 1.5e-73 246.2 15.6 1.5e-73 246.2 15.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KNZ73699.1 - 1e-09 38.2 12.8 1e-09 38.2 12.8 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain GPP34 PF05719.11 KNZ73700.1 - 2e-65 220.7 0.2 2.6e-65 220.3 0.2 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) G-alpha PF00503.20 KNZ73701.1 - 1.8e-97 326.7 0.0 3.6e-97 325.7 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ73701.1 - 1.3e-05 24.8 1.2 0.00033 20.1 0.1 3.0 3 0 0 3 3 3 1 ADP-ribosylation factor family Ribosomal_L33 PF00471.20 KNZ73702.1 - 3.4e-07 30.6 0.0 4.1e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 DUF2150 PF09920.9 KNZ73703.1 - 0.039 13.9 0.1 0.062 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) KdgT PF03812.13 KNZ73703.1 - 0.13 11.5 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease IL11 PF07400.11 KNZ73704.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Interleukin 11 DUF4031 PF13223.6 KNZ73704.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) DUF919 PF06034.11 KNZ73704.1 - 0.16 11.9 0.9 6.6 6.6 0.1 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Robl_LC7 PF03259.17 KNZ73705.1 - 8.1e-06 25.5 0.0 1.6e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain p450 PF00067.22 KNZ73706.1 - 8.1e-66 222.6 0.0 9.2e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KNZ73707.1 - 9.8e-85 285.0 0.0 1.1e-84 284.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HPP PF04982.13 KNZ73708.1 - 1.5e-42 144.6 4.7 1.5e-42 144.6 4.7 1.8 2 0 0 2 2 2 1 HPP family Ribosomal_L14e PF01929.17 KNZ73710.1 - 1e-30 106.0 0.5 2e-30 105.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KNZ73710.1 - 7.7e-05 22.5 0.1 0.00012 21.9 0.1 1.3 1 0 0 1 1 1 1 KOW motif DUF1838 PF08894.11 KNZ73711.1 - 2.3e-56 191.2 0.0 2.7e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1838) His_Phos_2 PF00328.22 KNZ73712.1 - 2.6e-25 89.6 0.0 4.5e-25 88.8 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_zinc_N PF00107.26 KNZ73713.1 - 9.8e-10 38.5 0.2 2.3e-09 37.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KNZ73713.1 - 7.1e-05 22.7 0.7 0.00018 21.3 0.7 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KNZ73713.1 - 0.00032 20.1 0.1 0.00048 19.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KNZ73713.1 - 0.0019 17.0 0.3 0.0033 16.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 KNZ73713.1 - 0.0077 15.7 0.0 0.037 13.5 0.0 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 KNZ73713.1 - 0.022 14.6 0.2 0.93 9.4 0.1 2.5 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Pyr_redox_2 PF07992.14 KNZ73713.1 - 0.032 13.5 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ73713.1 - 0.036 13.2 0.3 0.053 12.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 KNZ73713.1 - 0.1 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain UL42 PF17638.2 KNZ73715.1 - 0.11 12.4 0.2 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 HCMV UL42 Vac_ImportDeg PF09783.9 KNZ73716.1 - 0.041 13.7 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 Vacuolar import and degradation protein Pkinase_Tyr PF07714.17 KNZ73717.1 - 2.2e-52 177.9 0.0 3.2e-52 177.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ73717.1 - 1.9e-35 122.5 0.0 5e-35 121.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 KNZ73717.1 - 0.00083 18.8 0.1 0.0019 17.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2226 PF09987.9 KNZ73717.1 - 0.026 13.9 0.1 0.059 12.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) APH PF01636.23 KNZ73717.1 - 0.052 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ73717.1 - 0.078 12.6 0.2 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 RIO1 family HK97-gp10_like PF04883.12 KNZ73721.1 - 0.027 15.5 1.4 0.13 13.2 0.8 2.2 2 1 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component CSN7a_helixI PF18392.1 KNZ73721.1 - 0.17 11.8 1.4 0.44 10.5 1.4 1.7 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain eIF3_subunit PF08597.10 KNZ73721.1 - 1.1 9.1 6.6 0.5 10.2 4.4 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit CNH PF00780.22 KNZ73722.1 - 6.6e-52 176.8 0.0 1e-51 176.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KNZ73722.1 - 4.2e-38 131.4 0.6 5.3e-32 111.5 0.3 2.3 2 0 0 2 2 2 2 RhoGEF domain PH_5 PF15405.6 KNZ73722.1 - 4.5e-13 49.5 0.0 3e-12 46.8 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 KNZ73722.1 - 0.00047 20.1 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KNZ73722.1 - 0.054 14.0 0.0 0.2 12.2 0.0 2.1 1 1 0 1 1 1 0 PH domain zf-C2H2 PF00096.26 KNZ73723.1 - 0.0004 20.7 0.7 0.61 10.7 0.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ73723.1 - 0.01 16.6 0.7 1.2 10.2 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short_C2 PF13561.6 KNZ73724.1 - 2.4e-59 200.7 0.7 3.3e-59 200.3 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ73724.1 - 2.8e-49 167.3 2.5 3.9e-49 166.8 2.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ73724.1 - 3.3e-18 66.2 0.1 1.1e-17 64.6 0.1 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KNZ73724.1 - 1.9e-05 24.2 0.3 3.2e-05 23.5 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KNZ73724.1 - 8.7e-05 22.1 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KNZ73724.1 - 0.013 14.7 0.3 0.018 14.2 0.3 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein LDcluster4 PF18306.1 KNZ73724.1 - 0.041 13.5 0.1 0.085 12.4 0.1 1.4 1 0 0 1 1 1 0 SLOG cluster4 family Glyco_transf_5 PF08323.11 KNZ73724.1 - 0.068 12.9 0.0 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF4170 PF13773.6 KNZ73724.1 - 0.1 12.8 0.3 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) DUF2382 PF09557.10 KNZ73725.1 - 0.015 15.5 0.2 0.034 14.4 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2382) AAA_2 PF07724.14 KNZ73726.1 - 3.3e-47 160.8 0.0 3.5e-45 154.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KNZ73726.1 - 5.6e-33 113.0 5.9 6.9e-33 112.7 0.6 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KNZ73726.1 - 1.1e-20 73.4 2.4 3.9e-20 71.7 0.1 2.7 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KNZ73726.1 - 1.4e-18 67.5 0.1 1e-09 38.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KNZ73726.1 - 5.4e-17 62.1 0.0 7.1e-11 42.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KNZ73726.1 - 3e-10 40.5 1.0 0.003 17.9 0.0 4.8 4 2 0 4 4 4 2 AAA domain AAA_16 PF13191.6 KNZ73726.1 - 6.5e-09 36.4 5.3 0.0037 17.7 0.1 4.5 3 2 1 4 4 3 2 AAA ATPase domain Sigma54_activat PF00158.26 KNZ73726.1 - 2.3e-07 30.7 0.0 3.8e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KNZ73726.1 - 1.4e-06 27.8 0.1 0.2 11.0 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KNZ73726.1 - 1.8e-06 28.5 0.9 0.054 14.0 0.1 3.6 2 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 KNZ73726.1 - 7.2e-06 25.6 0.0 0.019 14.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KNZ73726.1 - 1.1e-05 25.3 0.0 0.0081 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KNZ73726.1 - 1.5e-05 24.8 0.2 0.2 11.4 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 KNZ73726.1 - 3.2e-05 24.0 0.0 0.041 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KNZ73726.1 - 5.8e-05 23.6 0.7 0.059 13.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 KNZ73726.1 - 8.5e-05 22.9 0.3 0.46 10.7 0.0 3.8 3 1 0 4 4 3 1 AAA domain RuvB_N PF05496.12 KNZ73726.1 - 0.00015 21.5 0.5 1.5 8.6 0.0 3.3 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KNZ73726.1 - 0.00048 20.5 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_29 PF13555.6 KNZ73726.1 - 0.00051 19.7 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Roc PF08477.13 KNZ73726.1 - 0.00086 19.5 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KNZ73726.1 - 0.00099 19.0 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 KNZ73726.1 - 0.0039 17.1 1.9 15 5.4 0.1 4.2 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 KNZ73726.1 - 0.0054 16.6 0.1 4.7 7.0 0.0 2.7 3 0 0 3 3 2 0 Bacterial dnaA protein T2SSE PF00437.20 KNZ73726.1 - 0.0064 15.6 0.0 0.074 12.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 KNZ73726.1 - 0.0079 15.9 0.0 1.2 8.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KNZ73726.1 - 0.0087 15.7 0.6 1.2 8.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 KNZ73726.1 - 0.013 15.8 0.1 0.52 10.6 0.0 2.8 2 1 1 3 3 2 0 AAA domain NTPase_1 PF03266.15 KNZ73726.1 - 0.013 15.4 0.4 9.1 6.2 0.0 3.6 4 0 0 4 4 3 0 NTPase ATP_bind_1 PF03029.17 KNZ73726.1 - 0.014 15.2 0.0 0.52 10.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 KNZ73726.1 - 0.014 15.9 13.0 0.46 11.0 0.0 3.5 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 KNZ73726.1 - 0.023 14.6 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KNZ73726.1 - 0.028 14.2 0.0 0.3 10.8 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 KNZ73726.1 - 0.034 14.3 0.0 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KNZ73726.1 - 0.046 13.3 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KNZ73726.1 - 0.054 13.5 0.0 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 KNZ73726.1 - 0.061 13.1 0.0 0.87 9.4 0.0 2.6 2 1 0 2 2 1 0 DNA polymerase III, delta subunit AAA_3 PF07726.11 KNZ73726.1 - 0.081 12.8 0.0 24 4.8 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KNZ73726.1 - 0.089 12.6 1.2 6.3 6.5 0.0 3.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 KNZ73726.1 - 0.098 12.1 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_15 PF13175.6 KNZ73726.1 - 0.12 12.0 0.1 31 4.1 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Cortex-I_coil PF09304.10 KNZ73726.1 - 0.13 12.4 7.3 1.8 8.8 6.4 3.1 3 0 0 3 3 2 0 Cortexillin I, coiled coil Rad17 PF03215.15 KNZ73726.1 - 0.14 12.0 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain EcoEI_R_C PF08463.10 KNZ73726.1 - 0.39 10.8 3.6 1.3 9.1 3.6 2.0 1 1 0 1 1 1 0 EcoEI R protein C-terminal Atg14 PF10186.9 KNZ73726.1 - 0.74 8.8 4.5 1.1 8.3 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GCV_T PF01571.21 KNZ73727.1 - 7.5e-76 254.9 0.0 8.9e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 KNZ73727.1 - 6.4e-23 80.5 0.0 1.2e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DeoC PF01791.9 KNZ73728.1 - 1.2e-13 51.3 2.9 1.5e-13 51.0 2.9 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Cu-oxidase PF00394.22 KNZ73729.1 - 5.7e-46 156.5 0.3 9.3e-44 149.3 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ73729.1 - 1.7e-38 131.3 0.0 1.8e-36 124.7 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ73729.1 - 8.6e-37 125.9 0.1 2.2e-33 114.9 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Lipase_chap PF03280.14 KNZ73730.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein TMF_TATA_bd PF12325.8 KNZ73731.1 - 0.027 14.7 3.0 0.047 13.9 3.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CEP209_CC5 PF16574.5 KNZ73731.1 - 0.032 14.4 1.4 0.045 13.9 1.4 1.2 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 APG6_N PF17675.1 KNZ73731.1 - 0.064 13.8 4.0 0.11 13.0 4.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region MBOAT_2 PF13813.6 KNZ73732.1 - 7.4e-22 77.4 1.3 2.4e-21 75.8 0.6 2.2 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family Helitron_like_N PF14214.6 KNZ73733.1 - 4.1e-35 121.7 1.7 5.2e-35 121.4 0.4 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Spore_GerQ PF09671.10 KNZ73733.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) SPC12 PF06645.13 KNZ73734.1 - 2.4e-28 98.0 0.9 2.6e-28 97.9 0.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) SPW PF03779.14 KNZ73734.1 - 0.42 10.2 7.1 0.68 9.6 7.1 1.4 1 0 0 1 1 1 0 SPW repeat QCR10 PF09796.9 KNZ73734.1 - 6.5 6.9 8.6 1.5 8.9 2.3 2.0 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) S_4TM PF18159.1 KNZ73734.1 - 6.7 5.9 5.2 8.1 5.6 5.2 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Pkinase PF00069.25 KNZ73735.1 - 3.6e-11 42.9 0.0 5.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ73735.1 - 8.3e-10 39.0 0.5 5.7e-06 26.4 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KNZ73735.1 - 5.8e-08 32.3 0.0 8.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KNZ73735.1 - 1.4e-05 24.8 1.5 2.1e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KNZ73735.1 - 3e-05 23.5 0.1 7.9e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNZ73735.1 - 0.00083 18.2 1.3 0.0014 17.5 1.3 1.4 1 1 0 1 1 1 1 Fungal protein kinase Radical_SAM_C PF16199.5 KNZ73736.1 - 1.6e-30 105.0 0.0 2.8e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KNZ73736.1 - 4.1e-17 63.0 0.1 1.4e-16 61.3 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KNZ73736.1 - 9.9e-11 41.9 0.1 2e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ73736.1 - 1.9e-06 27.8 0.0 4.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ73736.1 - 0.0023 18.3 0.0 0.0049 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ73736.1 - 0.04 13.9 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein MMM1 PF10296.9 KNZ73737.1 - 9.6e-13 47.9 0.0 1.6e-08 34.0 0.0 2.7 2 1 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 GDA1_CD39 PF01150.17 KNZ73738.1 - 1.4e-101 340.2 0.0 2.1e-101 339.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 KNZ73738.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Tyr_Deacylase PF02580.16 KNZ73739.1 - 2.3e-49 167.6 0.0 2.6e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 KNZ73740.1 - 5e-16 59.4 0.2 1e-13 51.8 0.0 2.0 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KNZ73741.1 - 6.7e-39 131.2 32.2 9.4e-07 29.5 0.3 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 KNZ73741.1 - 1.7e-13 50.2 3.0 4.4e-13 48.9 3.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ73741.1 - 1.5e-11 43.8 1.3 4.6e-11 42.3 1.3 1.9 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KNZ73741.1 - 2e-08 34.4 0.8 0.88 9.9 0.0 5.9 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ73741.1 - 2.1e-05 23.4 5.8 0.12 11.0 0.1 4.7 3 1 2 6 6 6 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KNZ73741.1 - 0.32 9.9 8.0 1.3 7.9 0.6 3.5 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Fungal_trans PF04082.18 KNZ73742.1 - 6.9e-15 54.8 0.4 1.3e-14 53.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GPI-anchored PF10342.9 KNZ73743.1 - 0.00089 20.0 0.0 0.0014 19.4 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Terpene_synth_C PF03936.16 KNZ73745.1 - 2.8e-06 26.9 0.0 4.4e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Adaptin_N PF01602.20 KNZ73745.1 - 0.078 11.5 0.0 0.16 10.5 0.0 1.5 2 0 0 2 2 2 0 Adaptin N terminal region DUF4537 PF15057.6 KNZ73747.1 - 0.00041 20.4 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 KNZ73747.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 KNZ73747.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 PWWP domain Nuc_sug_transp PF04142.15 KNZ73748.1 - 2.7e-98 329.0 10.4 5.1e-87 292.0 8.5 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter PUNUT PF16913.5 KNZ73748.1 - 0.00014 21.2 0.9 0.00014 21.2 0.9 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KNZ73748.1 - 0.00018 21.7 2.9 0.00018 21.7 2.9 3.1 3 1 0 3 3 3 1 EamA-like transporter family UAA PF08449.11 KNZ73748.1 - 0.0017 17.6 11.8 0.0052 16.0 11.8 1.8 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 KNZ73748.1 - 0.003 17.0 0.6 0.003 17.0 0.6 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family ECF-ribofla_trS PF07155.12 KNZ73748.1 - 0.79 9.7 9.2 0.068 13.2 3.3 2.2 3 0 0 3 3 3 0 ECF-type riboflavin transporter, S component Mit_ribos_Mrp51 PF11709.8 KNZ73749.1 - 5.2e-09 36.2 1.2 4e-08 33.2 1.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit RCR PF12273.8 KNZ73751.1 - 0.003 18.2 0.7 0.018 15.7 0.0 2.2 1 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Mid2 PF04478.12 KNZ73751.1 - 0.0097 15.7 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor HR1 PF02185.16 KNZ73751.1 - 0.015 15.4 1.0 0.025 14.7 1.0 1.3 1 0 0 1 1 1 0 Hr1 repeat TMEM154 PF15102.6 KNZ73751.1 - 0.049 13.5 0.3 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family SlyX PF04102.12 KNZ73751.1 - 0.062 13.9 2.9 0.27 11.9 0.3 2.3 2 0 0 2 2 2 0 SlyX EphA2_TM PF14575.6 KNZ73751.1 - 0.068 14.1 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Insulin_TMD PF17870.1 KNZ73751.1 - 0.11 12.6 0.3 0.25 11.5 0.3 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 KNZ73751.1 - 0.13 12.1 2.9 0.23 11.2 2.9 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FlxA PF14282.6 KNZ73751.1 - 1.1 9.3 13.1 12 5.9 13.1 2.2 1 1 0 1 1 1 0 FlxA-like protein SGL PF08450.12 KNZ73752.1 - 0.091 12.3 0.0 0.54 9.8 0.0 2.0 1 1 1 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region XRCC4 PF06632.12 KNZ73752.1 - 0.47 9.3 3.8 0.14 11.0 0.2 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PRKG1_interact PF15898.5 KNZ73752.1 - 1.1 10.2 5.7 0.37 11.7 1.3 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain WD40 PF00400.32 KNZ73752.1 - 2.6 9.1 5.5 1.3 10.0 0.3 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat ZapB PF06005.12 KNZ73752.1 - 2.7 8.5 7.8 0.33 11.4 2.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB GMC_oxred_C PF05199.13 KNZ73753.1 - 2.3e-10 41.1 0.1 2.8e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DUF5305 PF17231.2 KNZ73755.1 - 0.012 15.0 0.3 0.024 14.1 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) UPF1_Zn_bind PF09416.10 KNZ73757.1 - 3.2e-69 231.8 1.7 3.2e-69 231.8 1.7 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KNZ73757.1 - 4.4e-59 199.5 0.0 7.9e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ73757.1 - 6.8e-52 176.8 4.4 7.4e-31 107.9 1.5 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KNZ73757.1 - 4.4e-35 119.8 0.0 8.4e-35 118.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KNZ73757.1 - 2e-15 57.0 0.1 1.1e-14 54.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ73757.1 - 1.3e-11 45.1 0.2 4e-11 43.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ73757.1 - 7.4e-07 29.1 0.1 0.048 13.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KNZ73757.1 - 1.1e-05 24.8 0.1 0.00033 20.0 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KNZ73757.1 - 1.2e-05 25.4 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KNZ73757.1 - 0.00023 21.0 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 Helicase Ribosomal_S13_N PF08069.12 KNZ73757.1 - 0.011 15.7 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PIF1 PF05970.14 KNZ73757.1 - 0.017 14.3 0.2 0.65 9.1 0.0 2.3 1 1 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 KNZ73757.1 - 0.034 14.4 0.0 0.1 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KNZ73757.1 - 0.048 13.1 0.1 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 KNZ73757.1 - 0.074 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ribosomal_S27e PF01667.17 KNZ73757.1 - 0.075 12.8 0.5 0.25 11.1 0.5 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 DEAD PF00270.29 KNZ73757.1 - 0.085 12.6 0.4 0.23 11.2 0.1 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 KNZ73757.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.12 KNZ73757.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KNZ73757.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KNZ73757.1 - 0.18 11.1 0.0 0.49 9.7 0.0 1.7 2 0 0 2 2 2 0 KaiC ADH_N PF08240.12 KNZ73758.1 - 1.1e-09 38.1 0.1 1e-08 35.0 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ73758.1 - 7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ73758.1 - 0.17 12.9 0.0 0.5 11.4 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F-box-like PF12937.7 KNZ73759.1 - 0.0027 17.5 0.1 0.0077 16.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.23 KNZ73761.1 - 4.7e-47 160.4 0.0 1.5e-40 139.0 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ73761.1 - 2.3e-08 34.3 0.1 4.2e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GPI-anchored PF10342.9 KNZ73761.1 - 0.0003 21.5 0.0 0.00067 20.4 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DEAD PF00270.29 KNZ73761.1 - 0.0089 15.8 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KNZ73761.1 - 0.17 11.8 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pam17 PF08566.10 KNZ73762.1 - 6.9e-60 201.6 0.0 9e-60 201.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 SH3_9 PF14604.6 KNZ73763.1 - 4.1e-11 42.6 0.0 2e-10 40.3 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 KNZ73763.1 - 2.1e-05 24.1 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KNZ73763.1 - 0.00065 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_5 PF07728.14 KNZ73764.1 - 3.7e-10 39.9 0.0 7.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNZ73764.1 - 8.8e-09 35.7 0.0 1.8e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KNZ73764.1 - 0.00057 20.3 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ73764.1 - 0.0013 19.0 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ73764.1 - 0.014 15.7 0.0 0.14 12.5 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_PrkA PF08298.11 KNZ73764.1 - 0.031 13.2 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain RNA_helicase PF00910.22 KNZ73764.1 - 0.037 14.4 0.0 0.083 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KNZ73764.1 - 0.053 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KNZ73764.1 - 0.06 13.5 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KNZ73764.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF836 PF05768.14 KNZ73765.1 - 2.9e-11 43.6 0.0 6e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) zf-CCHC PF00098.23 KNZ73765.1 - 0.0014 18.6 0.2 0.0025 17.8 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Thioredoxin_3 PF13192.6 KNZ73765.1 - 0.037 14.1 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain BUD22 PF09073.10 KNZ73765.1 - 0.1 12.0 4.1 0.14 11.5 4.1 1.1 1 0 0 1 1 1 0 BUD22 Roughex PF06020.11 KNZ73765.1 - 0.2 10.8 5.0 0.29 10.2 5.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 KNZ73765.1 - 0.7 8.1 2.2 0.88 7.8 2.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Catalase PF00199.19 KNZ73766.1 - 2.1e-169 563.7 0.2 2.7e-169 563.3 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 KNZ73766.1 - 3e-14 52.9 0.0 5.9e-14 52.0 0.0 1.5 1 1 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 KNZ73766.1 - 2.4e-13 50.1 0.0 5e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 KNZ73766.1 - 2e-12 47.2 0.0 3.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Amidohydro_1 PF01979.20 KNZ73767.1 - 9.4e-66 222.5 0.0 1.1e-65 222.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KNZ73767.1 - 6.5e-09 35.8 0.1 2.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KNZ73767.1 - 0.00022 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Phosphodiest PF01663.22 KNZ73768.1 - 2.5e-11 43.8 0.5 3.9e-11 43.2 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KNZ73768.1 - 0.00034 20.1 0.1 0.00054 19.4 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KNZ73768.1 - 0.001 18.5 0.5 0.0018 17.7 0.5 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Hexapep PF00132.24 KNZ73769.1 - 4.3e-11 42.1 15.8 0.0002 20.9 0.4 4.1 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KNZ73769.1 - 0.0019 17.9 14.8 0.0092 15.7 6.2 3.3 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase mRNA_cap_enzyme PF01331.19 KNZ73771.1 - 3.3e-52 177.2 0.0 5e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KNZ73771.1 - 1.5e-31 109.2 0.1 2.5e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 KNZ73771.1 - 1.2e-09 38.2 0.0 2.6e-07 30.5 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Skp1 PF01466.19 KNZ73772.1 - 1.3e-29 102.0 0.3 2.2e-29 101.3 0.3 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KNZ73772.1 - 3.8e-24 84.6 1.0 7e-24 83.8 0.1 1.9 3 0 0 3 3 3 1 Skp1 family, tetramerisation domain BTB PF00651.31 KNZ73772.1 - 0.0017 18.5 0.0 0.076 13.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain Ribosomal_L27 PF01016.19 KNZ73773.1 - 1.4e-31 108.3 0.6 2e-31 107.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 KNZ73773.1 - 0.059 13.2 0.5 1 9.2 0.0 2.8 3 1 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region DUF3074 PF11274.8 KNZ73774.1 - 9e-34 117.1 0.0 2.7e-33 115.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) DUF1854 PF08909.11 KNZ73774.1 - 0.065 13.0 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) Gln-synt_C PF00120.24 KNZ73775.1 - 6.9e-73 245.6 0.0 2.1e-72 244.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amino_oxidase PF01593.24 KNZ73776.1 - 4e-27 95.6 0.0 4.9e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ73776.1 - 1.6e-11 44.3 2.3 6.1e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ73776.1 - 9.9e-08 31.9 3.8 9.8e-07 28.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ73776.1 - 0.028 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 KNZ73776.1 - 0.028 13.2 0.0 0.054 12.3 0.0 1.4 2 0 0 2 2 2 0 MCRA family Pyr_redox_2 PF07992.14 KNZ73776.1 - 0.029 13.6 0.6 0.39 9.9 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ73776.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ73776.1 - 0.39 11.3 2.1 3.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Glutaredoxin PF00462.24 KNZ73777.1 - 2.8e-17 62.7 0.0 4.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Herpes_ori_bp PF02399.15 KNZ73777.1 - 0.24 9.4 0.0 0.28 9.2 0.0 1.0 1 0 0 1 1 1 0 Origin of replication binding protein zf-DNL PF05180.12 KNZ73778.1 - 2.8e-29 100.9 0.2 3.5e-29 100.5 0.2 1.1 1 0 0 1 1 1 1 DNL zinc finger Zn_ribbon_SprT PF17283.2 KNZ73778.1 - 0.32 10.9 2.9 15 5.6 0.3 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Sporozoite_P67 PF05642.11 KNZ73778.1 - 6.5 4.7 8.0 7.6 4.5 8.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CASP_C PF08172.12 KNZ73782.1 - 0.03 13.7 0.2 0.041 13.2 0.2 1.1 1 0 0 1 1 1 0 CASP C terminal Aha1_N PF09229.11 KNZ73783.1 - 1.1e-30 106.6 0.1 2e-30 105.8 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 KNZ73783.1 - 8.4e-13 48.6 0.0 2.5e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein WD40 PF00400.32 KNZ73783.1 - 6.5e-06 26.8 1.2 0.0029 18.4 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ73783.1 - 0.021 15.1 0.0 4.3 7.7 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KNZ73783.1 - 0.069 13.7 0.9 4 8.1 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Terpene_synth_C PF03936.16 KNZ73784.1 - 2.2e-08 33.8 0.0 1.9e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KNZ73784.1 - 0.0076 15.1 0.2 0.32 9.8 0.1 2.1 2 0 0 2 2 2 2 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 KNZ73785.1 - 1.5e-07 31.0 0.0 4.9e-07 29.4 0.0 1.8 3 0 0 3 3 3 1 Terpene synthase family, metal binding domain TRI5 PF06330.11 KNZ73785.1 - 0.00033 19.6 0.0 0.004 16.1 0.0 2.1 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) SPOB_ab PF14682.6 KNZ73785.1 - 0.03 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal DUF3429 PF11911.8 KNZ73786.1 - 9.2e-40 136.3 15.5 1.3e-39 135.8 15.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF2378 PF09536.10 KNZ73786.1 - 0.033 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) SH3_9 PF14604.6 KNZ73787.1 - 3.5e-08 33.2 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ73787.1 - 4.4e-06 26.2 0.0 7.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SKG6 PF08693.10 KNZ73787.1 - 0.041 13.3 1.0 0.074 12.5 1.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF347 PF03988.12 KNZ73787.1 - 0.072 13.3 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) hSH3 PF14603.6 KNZ73787.1 - 0.083 13.3 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain Amnionless PF14828.6 KNZ73787.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 KNZ73787.1 - 0.16 12.8 0.0 0.31 12.0 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 KNZ73787.1 - 0.25 11.2 0.5 0.42 10.5 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Mucin PF01456.17 KNZ73787.1 - 1.9 8.5 13.7 4.1 7.4 13.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein WD40 PF00400.32 KNZ73788.1 - 3.6e-23 81.4 18.6 2.8e-05 24.8 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KNZ73788.1 - 2.3e-12 46.6 0.7 4.7e-12 45.6 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ73788.1 - 4.8e-08 32.7 0.6 9.6e-08 31.7 0.6 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KNZ73788.1 - 2e-07 30.0 1.1 0.043 12.5 0.0 4.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KNZ73788.1 - 1e-05 25.7 0.2 0.15 12.3 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KNZ73788.1 - 0.00061 19.5 0.0 0.0055 16.3 0.0 2.2 1 1 1 2 2 2 1 PQQ-like domain DUF5046 PF16465.5 KNZ73788.1 - 0.001 18.6 0.1 0.048 13.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) WD40_like PF17005.5 KNZ73788.1 - 0.011 15.0 0.2 0.1 11.9 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Kelch_2 PF07646.15 KNZ73788.1 - 0.14 12.2 0.6 4.2 7.5 0.0 3.1 2 1 0 2 2 2 0 Kelch motif Lipase_3 PF01764.25 KNZ73790.1 - 4.8e-06 26.5 0.1 1.9e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KNZ73790.1 - 0.0021 18.7 1.0 0.0024 18.5 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ73790.1 - 0.0045 16.7 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ73790.1 - 0.0046 16.3 0.0 0.0095 15.2 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 KNZ73790.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) G-gamma PF00631.22 KNZ73792.1 - 5.6e-23 80.7 0.0 6.2e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.22 KNZ73793.1 - 2.9e-13 49.6 0.2 3.2e-13 49.5 0.2 1.1 1 0 0 1 1 1 1 GGL domain Thioredoxin PF00085.20 KNZ73794.1 - 4.9e-22 77.9 0.0 6.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNZ73794.1 - 3.1e-07 30.8 0.0 4.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KNZ73794.1 - 2.5e-05 24.5 0.0 0.00028 21.1 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 KNZ73794.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 KNZ73794.1 - 0.009 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 KNZ73794.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KNZ73794.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like SPX PF03105.19 KNZ73795.1 - 1.7 8.5 7.3 1.9 8.3 7.3 1.1 1 0 0 1 1 1 0 SPX domain Pex14_N PF04695.13 KNZ73795.1 - 2 9.0 9.9 0.41 11.3 5.4 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Myotub-related PF06602.14 KNZ73796.1 - 2.4e-148 493.8 0.1 3.1e-148 493.4 0.1 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain HTH_29 PF13551.6 KNZ73796.1 - 0.03 14.3 0.0 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Y_phosphatase3 PF13350.6 KNZ73796.1 - 0.11 12.4 0.1 0.42 10.5 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KNZ73796.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase S-AdoMet_synt_C PF02773.16 KNZ73797.1 - 1.3e-67 226.1 0.4 2.8e-67 224.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KNZ73797.1 - 1.9e-47 160.4 0.0 3.6e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KNZ73797.1 - 1.3e-44 150.9 0.4 2.4e-44 150.0 0.4 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 KNZ73797.1 - 0.039 12.7 0.5 0.17 10.7 0.1 1.9 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) GATase_6 PF13522.6 KNZ73798.1 - 3.8e-13 49.8 0.0 1.1e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KNZ73798.1 - 7.5e-11 42.0 0.0 1.8e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KNZ73798.1 - 2.2e-09 37.0 0.2 3.7e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KNZ73798.1 - 5.8e-05 22.1 0.0 0.00016 20.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glyoxal_oxid_N PF07250.11 KNZ73799.1 - 4.5e-37 127.5 0.0 4e-36 124.4 0.0 2.4 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ73799.1 - 2.2e-19 69.5 0.0 6.3e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KNZ73799.1 - 0.067 13.2 0.4 18 5.4 0.0 3.6 4 0 0 4 4 4 0 Galactose oxidase, central domain AAA_18 PF13238.6 KNZ73800.1 - 2.9e-05 24.6 0.0 4.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 KNZ73800.1 - 8.5e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 KNZ73800.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KNZ73800.1 - 0.047 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain KH_8 PF17903.1 KNZ73801.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KNZ73801.1 - 0.0022 17.8 0.8 0.0053 16.5 0.8 1.6 1 0 0 1 1 1 1 KH domain Thr_synth_N PF14821.6 KNZ73802.1 - 9.9e-27 93.0 0.0 3.4e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 KNZ73802.1 - 4.5e-15 55.8 0.0 1e-14 54.7 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme UPF0160 PF03690.13 KNZ73803.1 - 4.8e-13 49.5 0.0 2.7e-12 47.0 0.0 1.7 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0160) p450 PF00067.22 KNZ73805.1 - 2.9e-66 224.1 0.0 6.2e-66 223.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.6 KNZ73806.1 - 0.12 13.0 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Med9 PF07544.13 KNZ73808.1 - 0.1 12.7 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Aminotran_1_2 PF00155.21 KNZ73813.1 - 8.1e-76 255.5 0.0 1.1e-75 255.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KNZ73813.1 - 7.1e-05 21.5 0.0 0.00016 20.4 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KNZ73813.1 - 0.00053 19.0 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Pertussis_S1 PF02917.14 KNZ73813.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.6 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Aminotran_3 PF00202.21 KNZ73814.1 - 3.7e-97 325.6 0.0 5.2e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Sec63 PF02889.16 KNZ73815.1 - 3.5e-69 232.8 0.0 5.2e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KNZ73815.1 - 5.3e-26 91.5 3.8 1.3e-18 67.3 0.8 4.3 3 2 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KNZ73815.1 - 6e-08 32.9 0.2 4.2e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNZ73815.1 - 1.1e-06 29.0 0.0 8.8e-05 22.8 0.0 4.0 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KNZ73815.1 - 0.0027 18.0 0.1 4.2 7.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KNZ73815.1 - 0.046 13.4 0.7 4.8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Aminotran_1_2 PF00155.21 KNZ73816.1 - 5.7e-61 206.7 0.0 6.4e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNZ73816.1 - 1e-06 28.3 0.0 3.2e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KNZ73816.1 - 5.2e-05 22.0 0.0 0.00024 19.8 0.0 2.0 2 1 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KNZ73816.1 - 0.0007 18.6 0.0 0.17 10.8 0.0 2.5 3 0 0 3 3 3 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNZ73816.1 - 0.004 16.5 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ank_2 PF12796.7 KNZ73817.1 - 4.4e-33 113.7 0.0 1.7e-13 50.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ73817.1 - 1.9e-31 107.7 0.8 3.5e-09 36.7 0.2 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ73817.1 - 6.2e-28 96.8 4.1 6.9e-14 52.0 0.4 4.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ73817.1 - 1.3e-23 80.5 1.2 8.8e-05 22.6 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 KNZ73817.1 - 2.4e-23 81.5 1.0 9.2e-06 25.9 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat FYVE PF01363.21 KNZ73817.1 - 1.3e-16 60.4 9.2 1.3e-16 60.4 9.2 2.6 3 0 0 3 3 2 1 FYVE zinc finger zf-RING_2 PF13639.6 KNZ73817.1 - 2.7e-08 34.0 4.7 2.7e-08 34.0 4.7 3.9 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ73817.1 - 1.3e-05 24.9 3.3 1.3e-05 24.9 3.3 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KNZ73817.1 - 0.00044 20.5 2.4 0.00044 20.5 2.4 2.7 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 KNZ73817.1 - 0.0045 16.7 5.0 0.0045 16.7 5.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 KNZ73817.1 - 0.018 15.2 4.2 0.054 13.7 2.9 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_9 PF13901.6 KNZ73817.1 - 0.26 11.3 9.7 0.31 11.0 1.6 3.4 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon HypA PF01155.19 KNZ73817.1 - 0.61 10.1 4.8 0.69 10.0 0.8 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4611 PF15387.6 KNZ73817.1 - 3.3 8.0 5.6 0.34 11.2 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FYVE_2 PF02318.16 KNZ73817.1 - 4.9 7.4 10.9 0.87 9.8 4.4 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.24 KNZ73817.1 - 5.6 7.2 9.6 2 8.6 4.3 2.7 2 0 0 2 2 2 0 B-box zinc finger PI31_Prot_N PF11566.8 KNZ73819.1 - 1.6e-46 158.0 0.0 2.2e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 KNZ73819.1 - 5.9e-10 40.2 23.4 3.1e-09 37.9 23.1 2.4 1 1 0 1 1 1 1 PI31 proteasome regulator DEAD PF00270.29 KNZ73820.1 - 2.3e-52 177.3 0.0 2.1e-51 174.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ73820.1 - 3e-26 91.9 0.0 1.5e-25 89.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ73820.1 - 4.4e-05 23.5 0.0 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NuDC PF16273.5 KNZ73820.1 - 0.26 11.8 0.0 0.26 11.8 0.0 4.3 5 0 0 5 5 5 0 Nuclear distribution C domain Nsp1_C PF05064.13 KNZ73821.1 - 2.2e-28 98.4 2.1 2.2e-28 98.4 2.1 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 KNZ73821.1 - 4.1e-07 30.8 56.1 4.5e-05 24.2 26.1 5.7 2 1 4 6 6 6 3 Nucleoporin FG repeat region FlaC_arch PF05377.11 KNZ73821.1 - 0.085 13.3 7.5 0.34 11.3 1.3 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KNZ73821.1 - 0.17 11.9 6.6 1 9.4 0.1 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MurB_C PF02873.16 KNZ73821.1 - 0.96 9.5 6.1 0.47 10.5 0.4 2.8 3 0 0 3 3 3 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Deltameth_res PF16020.5 KNZ73822.1 - 0.56 10.1 0.0 0.56 10.1 0.0 3.2 3 0 0 3 3 3 0 Deltamethrin resistance YtpI PF14007.6 KNZ73822.1 - 2.7 8.2 12.0 1.9 8.7 1.0 2.9 3 0 0 3 3 3 0 YtpI-like protein DUF952 PF06108.12 KNZ73823.1 - 6.5e-22 77.3 0.0 8.9e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) AAA_22 PF13401.6 KNZ73824.1 - 0.00076 19.8 0.2 0.61 10.4 0.2 2.9 1 1 0 1 1 1 1 AAA domain DUF87 PF01935.17 KNZ73824.1 - 0.0019 18.3 0.1 0.053 13.6 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 KNZ73824.1 - 0.003 18.0 0.1 0.44 11.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 KNZ73824.1 - 0.0058 16.3 0.0 0.025 14.2 0.0 1.9 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_10 PF12846.7 KNZ73824.1 - 0.016 14.2 0.0 0.74 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 KNZ73824.1 - 0.019 14.3 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 KNZ73824.1 - 0.078 11.8 0.0 0.19 10.5 0.1 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_16 PF13191.6 KNZ73824.1 - 0.086 13.2 0.1 4.8 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 KNZ73824.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.29 KNZ73824.1 - 0.15 11.8 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Methyltransf_8 PF05148.15 KNZ73825.1 - 1.2e-67 228.0 0.0 3.2e-67 226.6 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KNZ73825.1 - 3.1e-08 34.2 0.1 2.2e-07 31.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ73825.1 - 2e-06 28.4 0.1 2.3e-05 25.0 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ73825.1 - 1.2e-05 25.3 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73825.1 - 0.00028 21.6 0.1 0.0016 19.1 0.0 2.4 2 2 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73825.1 - 0.00077 19.3 0.0 0.043 13.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ73825.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPRTase PF14681.6 KNZ73826.1 - 9.9e-66 221.1 0.0 1.1e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KNZ73826.1 - 0.053 13.0 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CEND1 PF15677.5 KNZ73826.1 - 0.19 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 FAD_binding_1 PF00667.20 KNZ73827.1 - 3e-51 174.1 0.0 4.6e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KNZ73827.1 - 2.8e-08 34.4 0.0 9.9e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.18 KNZ73827.1 - 0.00054 20.1 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Pox_F12L PF03337.13 KNZ73827.1 - 0.044 11.9 0.1 0.065 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus F12L protein FAD_binding_6 PF00970.24 KNZ73827.1 - 0.051 13.9 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.19 KNZ73828.1 - 3.5e-77 260.6 7.6 4.9e-77 260.1 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Wtap PF17098.5 KNZ73829.1 - 0.0092 15.9 1.8 0.015 15.2 1.8 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family SWIRM-assoc_1 PF16495.5 KNZ73829.1 - 0.06 13.3 2.2 0.12 12.3 2.2 1.4 1 0 0 1 1 1 0 SWIRM-associated region 1 AAA_23 PF13476.6 KNZ73829.1 - 0.32 11.5 1.4 0.61 10.6 1.4 1.4 1 0 0 1 1 1 0 AAA domain Mei5 PF10376.9 KNZ73830.1 - 0.022 14.6 0.3 0.034 14.0 0.3 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF4094 PF13334.6 KNZ73830.1 - 0.12 12.8 0.7 5.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) IFP_35_N PF07334.13 KNZ73830.1 - 0.14 12.3 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Rho_GDI PF02115.17 KNZ73831.1 - 1.3e-55 188.2 0.0 1.5e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UbiA PF01040.18 KNZ73832.1 - 7.7e-36 123.7 19.2 2.3e-35 122.1 19.2 1.8 1 1 0 1 1 1 1 UbiA prenyltransferase family Rep_fac-A_3 PF08661.11 KNZ73833.1 - 1.3e-16 60.9 0.3 1.4e-16 60.7 0.3 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Plk4_PB1 PF18190.1 KNZ73833.1 - 0.027 14.6 0.3 0.034 14.3 0.3 1.2 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 Ytp1 PF10355.9 KNZ73834.1 - 8.6e-107 356.5 6.9 1.3e-106 355.9 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KNZ73834.1 - 1.1e-13 50.9 1.0 1.1e-13 50.9 1.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SK_channel PF03530.14 KNZ73834.1 - 0.83 9.7 5.2 0.75 9.8 0.7 2.6 3 0 0 3 3 3 0 Calcium-activated SK potassium channel MFS_1 PF07690.16 KNZ73835.1 - 8.6e-35 120.3 14.8 1.5e-34 119.5 14.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KNZ73835.1 - 5.8e-05 22.5 0.3 5.8e-05 22.5 0.3 1.7 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB GFO_IDH_MocA PF01408.22 KNZ73838.1 - 3.2e-20 73.1 0.1 6.1e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KNZ73838.1 - 8e-06 25.9 0.0 2.6e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain IlvN PF07991.12 KNZ73838.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF1615 PF07759.12 KNZ73838.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) Abhydrolase_6 PF12697.7 KNZ73839.1 - 2.1e-14 54.7 10.8 2.8e-14 54.3 10.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ73839.1 - 1.5e-09 37.5 0.1 9.8e-08 31.5 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ73839.1 - 2.2e-05 24.2 1.0 0.0048 16.6 0.4 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KNZ73839.1 - 6.4e-05 22.9 1.4 0.11 12.4 0.3 2.3 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_8 PF06259.12 KNZ73839.1 - 0.037 13.7 1.2 0.13 11.9 0.8 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase CDT1_C PF16679.5 KNZ73840.1 - 5.6e-15 55.5 0.2 1.9e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain DUF908 PF06012.12 KNZ73840.1 - 8.6 5.7 6.3 2.5 7.5 2.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) GFO_IDH_MocA PF01408.22 KNZ73841.1 - 3e-22 79.7 0.2 5.8e-22 78.8 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KNZ73841.1 - 1.6e-10 41.0 0.0 3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KNZ73841.1 - 0.075 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 KNZ73841.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ubiquitin PF00240.23 KNZ73842.1 - 2.6e-07 30.3 0.0 4.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KNZ73842.1 - 0.029 14.9 0.0 0.13 12.8 0.0 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain cNMP_binding PF00027.29 KNZ73843.1 - 8.8e-36 121.9 0.1 3.3e-18 65.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 KNZ73843.1 - 7e-12 44.8 0.1 1.7e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Proteasome PF00227.26 KNZ73844.1 - 3.2e-43 147.4 0.2 3.7e-43 147.2 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit CSN8_PSD8_EIF3K PF10075.9 KNZ73845.1 - 3.8e-28 98.3 0.0 5.8e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 KNZ73845.1 - 7.4e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 KNZ73846.1 - 6.1e-50 169.3 0.0 7.5e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KNZ73846.1 - 4.1e-09 35.9 4.9 6.7e-07 28.9 0.3 2.4 2 0 0 2 2 2 2 Proteasome subunit A N-terminal signature DUF5633 PF18656.1 KNZ73846.1 - 7.1 6.6 6.6 4.6 7.2 3.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Nup88 PF10168.9 KNZ73847.1 - 1.5e-23 82.6 0.1 2.7e-12 45.4 0.0 3.3 3 0 0 3 3 3 3 Nuclear pore component Nup54 PF13874.6 KNZ73847.1 - 0.00064 19.8 3.1 0.00064 19.8 3.1 1.8 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 ANAPC4_WD40 PF12894.7 KNZ73847.1 - 0.071 13.4 0.0 28 5.1 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 KNZ73848.1 - 3.5e-32 111.7 26.4 4.9e-32 111.2 26.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 KNZ73849.1 - 3.2e-89 299.4 0.3 3.6e-89 299.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.22 KNZ73850.1 - 2.1e-45 155.3 0.0 3.4e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UBX PF00789.20 KNZ73851.1 - 1.7e-13 50.6 0.4 3.2e-13 49.7 0.4 1.4 1 0 0 1 1 1 1 UBX domain WYL PF13280.6 KNZ73851.1 - 0.044 13.8 0.1 0.066 13.3 0.1 1.2 1 0 0 1 1 1 0 WYL domain PITH PF06201.13 KNZ73852.1 - 5.5e-38 130.6 0.0 6.9e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 PITH domain Mg_trans_NIPA PF05653.14 KNZ73853.1 - 6.5e-54 183.0 9.0 8.1e-54 182.7 9.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KNZ73853.1 - 5.6e-06 26.6 0.2 5.6e-06 26.6 0.2 2.8 2 1 0 2 2 2 1 EamA-like transporter family VMA21 PF09446.10 KNZ73853.1 - 0.031 14.4 0.9 0.11 12.6 0.9 1.9 1 0 0 1 1 1 0 VMA21-like domain Trp_oprn_chp PF09534.10 KNZ73853.1 - 4 7.2 5.5 1.5 8.6 2.5 1.9 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) WD40 PF00400.32 KNZ73854.1 - 0.00025 21.8 0.1 0.0026 18.6 0.0 2.6 3 0 0 3 3 3 1 WD domain, G-beta repeat Nop10p PF04135.12 KNZ73854.1 - 0.012 15.6 0.2 0.04 14.0 0.0 1.9 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family PAD_N PF08526.10 KNZ73854.1 - 0.11 12.9 0.5 1.5 9.2 0.1 2.4 2 1 0 2 2 2 0 Protein-arginine deiminase (PAD) N-terminal domain TFIID-31kDa PF02291.15 KNZ73855.1 - 3.5e-35 120.7 0.0 4.9e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KNZ73855.1 - 0.00014 21.9 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KNZ73855.1 - 0.00037 20.8 0.0 0.00091 19.6 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 KNZ73855.1 - 0.00081 19.3 0.0 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 KNZ73855.1 - 0.04 14.3 0.0 0.067 13.5 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NifU_N PF01592.16 KNZ73856.1 - 2.8e-50 169.8 0.0 3.7e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Nop PF01798.18 KNZ73857.1 - 2.2e-65 220.3 0.0 7.7e-44 149.9 0.1 2.3 2 0 0 2 2 2 2 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 KNZ73857.1 - 1e-37 129.7 5.0 1.7e-37 129.0 5.0 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Pkinase PF00069.25 KNZ73858.1 - 7.8e-62 209.0 0.0 2.2e-61 207.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73858.1 - 1e-25 90.5 0.0 3.3e-24 85.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ73858.1 - 0.0089 15.4 0.2 3.8 6.7 0.1 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KNZ73858.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KNZ73858.1 - 0.33 10.5 1.4 1 8.9 1.4 1.7 1 1 0 1 1 1 0 RIO1 family PEX11 PF05648.14 KNZ73860.1 - 9.5e-13 48.1 2.5 1.9e-10 40.6 2.5 3.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) SNARE_assoc PF09335.11 KNZ73861.1 - 3.9e-14 53.2 7.1 3.9e-14 53.2 7.1 2.0 1 1 1 2 2 2 1 SNARE associated Golgi protein DUF1772 PF08592.11 KNZ73861.1 - 0.12 12.7 7.6 0.7 10.2 0.0 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 KNZ73862.1 - 5.8e-69 232.4 0.0 7.8e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73862.1 - 1.1e-27 97.0 0.0 1.2e-19 70.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNZ73862.1 - 7.6e-08 32.0 0.0 0.35 10.1 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KNZ73862.1 - 0.00034 19.5 1.2 0.0043 15.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KNZ73862.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ73862.1 - 0.44 9.4 0.0 0.44 9.4 0.0 1.9 3 0 0 3 3 3 0 Haspin like kinase domain MFS_1 PF07690.16 KNZ73863.1 - 8.9e-38 130.1 40.0 1.3e-37 129.5 38.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily COA2 PF17051.5 KNZ73864.1 - 7.7e-08 32.3 0.0 9.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 COX14 PF14880.6 KNZ73864.1 - 0.32 10.9 0.9 0.72 9.7 0.9 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Ribosomal_S14 PF00253.21 KNZ73865.1 - 4.4e-21 74.4 1.6 6.7e-21 73.8 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.8 KNZ73866.1 - 9.7e-14 51.4 0.0 4.5e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KNZ73866.1 - 0.0021 18.1 4.4 0.0041 17.2 4.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor Pneumo_att_G PF05539.11 KNZ73866.1 - 0.093 12.3 0.4 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DNA_RNApol_7kD PF03604.13 KNZ73867.1 - 2.6e-17 62.2 8.4 3.6e-17 61.7 8.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 KNZ73867.1 - 0.002 18.0 0.2 0.0027 17.5 0.2 1.1 1 0 0 1 1 1 1 MCM OB domain zinc_ribbon_10 PF10058.9 KNZ73867.1 - 0.0043 16.7 0.3 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Zn_ribbon_recom PF13408.6 KNZ73867.1 - 0.0067 16.9 1.3 0.22 12.1 0.1 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 KNZ73867.1 - 0.0078 16.3 1.8 0.016 15.3 1.8 1.5 1 0 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 KNZ73867.1 - 0.013 15.5 0.7 0.021 14.9 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 KNZ73867.1 - 0.015 15.2 0.6 0.077 12.9 0.9 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain HypA PF01155.19 KNZ73867.1 - 0.025 14.6 0.6 0.036 14.1 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_2 PF13240.6 KNZ73867.1 - 0.028 14.1 1.4 0.067 12.9 1.4 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-C3HC PF07967.13 KNZ73867.1 - 0.037 14.1 0.1 0.041 13.9 0.1 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like GFA PF04828.14 KNZ73867.1 - 0.055 13.8 0.6 0.73 10.2 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-trcl PF13451.6 KNZ73867.1 - 0.095 12.6 5.9 0.85 9.6 0.2 2.3 1 1 1 2 2 2 0 Probable zinc-ribbon domain TF_Zn_Ribbon PF08271.12 KNZ73867.1 - 0.099 12.2 2.3 1.3 8.5 0.1 2.3 1 1 1 2 2 2 0 TFIIB zinc-binding DUF2688 PF10892.8 KNZ73867.1 - 0.12 11.9 1.8 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Ribosomal_L37e PF01907.19 KNZ73867.1 - 0.19 11.9 2.8 4 7.7 2.2 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e zf-Sec23_Sec24 PF04810.15 KNZ73867.1 - 0.35 11.0 2.8 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-ribbon_3 PF13248.6 KNZ73867.1 - 0.37 10.3 2.3 1.7 8.2 2.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 KNZ73867.1 - 0.38 10.5 4.0 11 5.8 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf_UBZ PF18439.1 KNZ73867.1 - 0.69 9.6 2.3 14 5.4 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger MAP65_ASE1 PF03999.12 KNZ73868.1 - 0.72 8.5 10.9 0.9 8.2 10.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4187 PF13821.6 KNZ73869.1 - 3.4e-21 74.7 1.4 5.9e-21 74.0 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KNZ73869.1 - 3e-05 23.8 1.9 4.6e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KNZ73869.1 - 0.1 12.7 0.2 0.48 10.5 0.2 2.1 1 1 0 1 1 1 0 G-patch domain RRM_1 PF00076.22 KNZ73870.1 - 8.2e-28 96.0 0.0 1.4e-12 47.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 KNZ73870.1 - 0.0083 16.1 0.1 3.7 7.6 0.0 2.5 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_5 PF13893.6 KNZ73870.1 - 0.014 15.0 0.0 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Totivirus_coat PF05518.11 KNZ73870.1 - 0.015 13.4 7.7 0.019 13.0 7.7 1.1 1 0 0 1 1 1 0 Totivirus coat protein OB_RNB PF08206.11 KNZ73870.1 - 0.23 11.2 3.5 28 4.5 0.0 3.2 2 1 0 2 2 2 0 Ribonuclease B OB domain Glyco_hydro_cc PF11790.8 KNZ73871.1 - 1.2e-62 211.6 3.5 1.6e-62 211.2 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ATF7IP_BD PF16788.5 KNZ73871.1 - 6.2 6.9 7.2 10 6.2 7.2 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain FSA_C PF10479.9 KNZ73871.1 - 7.1 4.6 10.4 9.6 4.2 10.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Ribosomal_L11 PF00298.19 KNZ73874.1 - 5.2e-30 103.8 0.4 8.4e-30 103.1 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KNZ73874.1 - 5.6e-27 93.4 0.7 8.9e-27 92.7 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.17 KNZ73875.1 - 2.6e-23 82.7 0.1 5.2e-23 81.8 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KNZ73875.1 - 9.2e-08 32.0 0.0 1.6e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KNZ73875.1 - 0.007 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Nicastrin Asp PF00026.23 KNZ73877.1 - 1.1e-28 100.6 0.1 7.3e-27 94.6 0.1 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ73877.1 - 0.0042 17.3 1.7 0.072 13.3 1.7 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Esterase_phd PF10503.9 KNZ73878.1 - 9.1e-12 44.9 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KNZ73878.1 - 2.8e-11 43.1 7.8 7.8e-11 41.7 7.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KNZ73878.1 - 5.6e-08 32.5 0.3 9.1e-08 31.8 0.3 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KNZ73878.1 - 1.6e-05 24.7 0.2 2.2e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KNZ73878.1 - 0.019 13.7 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Sporozoite_P67 PF05642.11 KNZ73878.1 - 0.21 9.6 2.5 0.24 9.4 2.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF262 PF03235.14 KNZ73879.1 - 5.6e-16 59.4 0.1 2.6e-15 57.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF262 Tannase PF07519.11 KNZ73880.1 - 6e-100 335.4 0.0 7.8e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KNZ73880.1 - 0.00041 20.1 0.0 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ73880.1 - 0.0079 15.5 0.0 0.32 10.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 F-box-like PF12937.7 KNZ73881.1 - 1.1e-06 28.4 1.4 9.6e-06 25.4 0.2 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ73881.1 - 5.3 7.0 10.6 6.7 6.7 5.4 3.3 2 1 0 2 2 2 0 F-box domain Helitron_like_N PF14214.6 KNZ73882.1 - 4.7e-45 154.2 0.2 7.1e-45 153.6 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus rve PF00665.26 KNZ73883.1 - 2.5e-05 24.4 0.0 6.4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Integrase core domain Hepar_II_III PF07940.13 KNZ73883.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Heparinase II/III-like protein AIM3 PF17096.5 KNZ73884.1 - 0.017 16.1 0.0 0.033 15.1 0.0 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Med2 PF11214.8 KNZ73884.1 - 0.062 13.4 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Ax_dynein_light PF10211.9 KNZ73885.1 - 0.016 15.2 2.3 0.035 14.1 2.3 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Cep57_CLD PF14073.6 KNZ73885.1 - 0.024 14.7 5.4 0.044 13.8 5.4 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 CTP_transf_like PF01467.26 KNZ73885.1 - 0.029 14.5 2.4 0.16 12.2 2.3 2.1 1 1 0 1 1 1 0 Cytidylyltransferase-like BMFP PF04380.13 KNZ73885.1 - 0.085 13.4 3.9 0.28 11.7 2.3 2.5 2 0 0 2 2 2 0 Membrane fusogenic activity SlyX PF04102.12 KNZ73885.1 - 0.1 13.2 1.0 0.66 10.6 1.4 2.1 2 0 0 2 2 2 0 SlyX DUF3552 PF12072.8 KNZ73885.1 - 0.16 11.4 7.6 0.26 10.7 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4200 PF13863.6 KNZ73885.1 - 0.36 11.3 6.6 3.1 8.2 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TP53IP5 PF15331.6 KNZ73886.1 - 7.2 6.7 5.9 32 4.6 5.9 2.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 eIF-5_eIF-2B PF01873.17 KNZ73887.1 - 2.2e-39 133.9 0.1 4.4e-39 133.0 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KNZ73887.1 - 4.6e-16 58.7 0.1 2.2e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon ATP-synt_F PF01990.17 KNZ73887.1 - 0.02 15.2 0.0 0.063 13.6 0.0 1.8 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit F_actin_cap_B PF01115.17 KNZ73888.1 - 5.2e-104 347.1 0.0 7.3e-104 346.6 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 KNZ73888.1 - 0.048 13.1 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 F-actin capping protein alpha subunit Pro_isomerase PF00160.21 KNZ73889.1 - 2.9e-27 95.9 0.1 3.3e-27 95.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD G-alpha PF00503.20 KNZ73890.1 - 1e-116 390.0 0.1 1.2e-116 389.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ73890.1 - 1.4e-13 50.7 0.0 1.2e-10 41.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KNZ73890.1 - 3.6e-05 24.0 0.1 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KNZ73890.1 - 8.1e-05 22.3 0.1 0.014 15.0 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_24 PF13479.6 KNZ73890.1 - 0.0013 18.5 0.0 0.045 13.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 KNZ73890.1 - 0.0048 16.3 0.1 0.77 9.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 KNZ73890.1 - 0.028 13.8 0.1 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 KNZ73890.1 - 0.089 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KNZ73890.1 - 0.12 12.3 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 KNZ73890.1 - 0.12 12.2 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KNZ73890.1 - 0.12 11.9 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain BCD PF15461.6 KNZ73890.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase HLH PF00010.26 KNZ73891.1 - 1.6e-06 27.9 0.0 7.9e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain THUMP PF02926.17 KNZ73892.1 - 3.6e-11 43.4 0.1 5.1e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 THUMP domain Adipokin_hormo PF06377.11 KNZ73892.1 - 0.19 12.1 0.6 28 5.2 0.1 2.7 2 1 0 2 2 2 0 Adipokinetic hormone NUDIX PF00293.28 KNZ73893.1 - 4.1e-10 39.8 0.2 5.9e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.22 KNZ73894.1 - 4.6e-42 144.4 17.2 4.1e-40 138.0 17.2 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter HD PF01966.22 KNZ73895.1 - 0.00011 22.4 0.1 0.00032 20.9 0.1 1.8 1 1 0 1 1 1 1 HD domain PEX11 PF05648.14 KNZ73896.1 - 1e-11 44.8 0.2 1.4e-10 41.0 0.2 2.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) GMC_oxred_N PF00732.19 KNZ73897.1 - 4.7e-52 177.2 0.0 6.2e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ73897.1 - 9.2e-36 123.5 0.0 2e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KNZ73897.1 - 0.00012 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ73897.1 - 0.0053 17.0 0.1 0.018 15.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KNZ73897.1 - 0.026 13.8 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KNZ73897.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_pol3_delta2 PF13177.6 KNZ73898.1 - 2.7e-12 46.8 0.1 5.2e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KNZ73898.1 - 0.00024 21.5 0.5 0.00057 20.3 0.5 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ73898.1 - 0.0042 17.5 0.1 0.011 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 KNZ73898.1 - 0.014 15.2 0.2 0.023 14.5 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF1820 PF08850.11 KNZ73898.1 - 0.034 14.6 0.0 0.075 13.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) AAA_33 PF13671.6 KNZ73898.1 - 0.052 13.7 0.1 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KNZ73898.1 - 0.054 12.9 0.1 0.23 10.8 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KNZ73898.1 - 0.1 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Phyto-Amp PF15438.6 KNZ73898.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma AAA_22 PF13401.6 KNZ73898.1 - 0.21 11.9 1.4 1.8 8.9 1.0 2.5 2 1 0 2 2 2 0 AAA domain Glyco_hydro_10 PF00331.20 KNZ73899.1 - 4.9e-96 321.6 0.0 5.5e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Methyltransf_23 PF13489.6 KNZ73900.1 - 2.5e-05 24.2 0.0 5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73900.1 - 0.0069 16.2 0.1 0.065 13.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KNZ73900.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.6 KNZ73900.1 - 0.03 15.0 0.1 2.7 8.8 0.1 3.0 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73900.1 - 0.04 14.6 0.0 0.28 12.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KNZ73900.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain ATP_synt_H PF05493.13 KNZ73901.1 - 5.3e-17 62.0 3.9 6.6e-17 61.7 3.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.6 KNZ73901.1 - 0.036 14.2 0.3 0.047 13.8 0.3 1.3 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF4131 PF13567.6 KNZ73901.1 - 0.58 9.8 5.0 0.61 9.7 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TGBp3 PF02495.17 KNZ73901.1 - 2.3 8.0 6.4 2.4 7.9 0.2 2.3 1 1 1 2 2 2 0 Triple gene block 3 Glyco_hydro_10 PF00331.20 KNZ73902.1 - 8.8e-105 350.3 0.0 1e-104 350.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KNZ73902.1 - 2.1e-12 46.7 12.0 2.1e-12 46.7 12.0 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain CRIM PF16978.5 KNZ73902.1 - 0.19 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain RAI1 PF08652.11 KNZ73904.1 - 5e-22 77.9 0.0 9.5e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Whi5 PF08528.11 KNZ73905.1 - 9.6e-05 21.9 0.1 0.00017 21.1 0.1 1.4 1 0 0 1 1 1 1 Whi5 like Sugar_tr PF00083.24 KNZ73906.1 - 8.6e-110 367.7 15.0 1.1e-109 367.4 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ73906.1 - 1.1e-18 67.4 33.5 5.1e-18 65.1 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyt-b5 PF00173.28 KNZ73907.1 - 1.7e-18 66.6 0.0 2.5e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TauD PF02668.16 KNZ73910.1 - 1.2e-59 202.3 0.3 1.5e-59 202.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glycos_transf_3 PF00591.21 KNZ73912.1 - 2.4e-73 246.9 0.0 3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KNZ73912.1 - 6.5e-08 32.3 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain TRI5 PF06330.11 KNZ73913.1 - 1e-23 83.8 1.5 1.2e-23 83.6 1.5 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF2521 PF10730.9 KNZ73913.1 - 0.023 14.7 0.5 0.049 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) Retrotran_gag_2 PF14223.6 KNZ73914.1 - 5.3e-16 58.5 0.8 8e-16 58.0 0.8 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ73914.1 - 7.1e-05 22.4 0.6 0.00015 21.4 0.6 1.5 1 0 0 1 1 1 1 C2H2 zinc-finger TolA_bind_tri PF16331.5 KNZ73914.1 - 0.049 13.7 0.8 0.12 12.5 0.8 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation Retrotran_gag_3 PF14244.6 KNZ73914.1 - 0.063 13.1 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type ZapA PF05164.13 KNZ73914.1 - 0.081 13.4 3.2 0.26 11.8 3.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapA DUF4219 PF13961.6 KNZ73914.1 - 0.1 12.3 0.7 0.23 11.2 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Herpes_V23 PF01802.17 KNZ73914.1 - 0.15 11.5 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein NAPRTase_N PF17767.1 KNZ73914.1 - 0.19 12.1 1.1 0.56 10.6 0.0 2.2 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Glyoxalase_4 PF13669.6 KNZ73916.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3461 PF11944.8 KNZ73916.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) FAM199X PF15814.5 KNZ73916.1 - 0.11 11.6 0.2 0.17 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein family FAM199X HsbA PF12296.8 KNZ73919.1 - 8.2e-17 61.7 0.4 1.1e-16 61.3 0.4 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF4393 PF14337.6 KNZ73919.1 - 0.028 14.2 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) CMAS PF02353.20 KNZ73920.1 - 1.9e-43 148.7 0.0 4.5e-43 147.5 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KNZ73920.1 - 9.4e-08 32.7 0.0 2.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ73920.1 - 3.8e-06 27.4 0.0 8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ73920.1 - 1.1e-05 25.3 0.0 3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ73920.1 - 0.0011 19.6 0.0 0.0019 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ73920.1 - 0.0046 16.8 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ73920.1 - 0.04 13.5 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KNZ73920.1 - 0.071 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 KNZ73920.1 - 0.17 11.5 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 KNZ73920.1 - 0.19 11.4 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 KNZ73921.1 - 6.3e-64 216.4 0.0 8.2e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Na_H_Exchanger PF00999.21 KNZ73922.1 - 1.2e-25 90.1 31.8 3.5e-25 88.6 31.8 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Thiolase_N PF00108.23 KNZ73923.1 - 4.7e-05 22.9 0.0 0.00058 19.3 0.0 2.0 1 1 0 2 2 2 2 Thiolase, N-terminal domain Fic PF02661.18 KNZ73924.1 - 0.011 16.6 0.0 7.4 7.5 0.1 2.6 1 1 1 2 2 2 0 Fic/DOC family Aromatic_hydrox PF11723.8 KNZ73924.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Homotrimeric ring hydroxylase Fic PF02661.18 KNZ73925.1 - 0.015 16.1 0.0 11 7.0 0.0 3.0 3 0 0 3 3 3 0 Fic/DOC family JAB PF01398.21 KNZ73926.1 - 1.3e-14 54.2 0.1 1.3e-14 54.2 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 KNZ73926.1 - 1.3e-07 31.4 0.1 3.5e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Asp PF00026.23 KNZ73927.1 - 2.1e-31 109.5 0.1 2.9e-30 105.8 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ73927.1 - 3.3e-05 24.2 0.8 0.0013 19.0 0.8 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ73927.1 - 0.021 15.5 0.5 0.28 11.8 0.1 2.9 3 0 0 3 3 3 0 Aspartyl protease PB1 PF00564.24 KNZ73928.1 - 1.5e-13 50.5 0.0 3.4e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain G-patch PF01585.23 KNZ73928.1 - 5.9e-07 29.3 0.6 1.5e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 G-patch domain TPR_12 PF13424.6 KNZ73928.1 - 9.6e-06 25.8 0.8 0.00082 19.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ73928.1 - 2.9e-05 23.9 0.9 0.00048 20.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73928.1 - 0.00037 20.4 4.3 0.068 13.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ73928.1 - 0.0023 17.6 0.1 0.0075 15.9 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 KNZ73928.1 - 0.0045 16.8 2.7 0.027 14.3 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat G-patch_2 PF12656.7 KNZ73928.1 - 0.01 15.9 0.1 0.01 15.9 0.1 3.3 3 1 0 3 3 3 0 G-patch domain TPR_7 PF13176.6 KNZ73928.1 - 0.069 13.2 1.0 1.5 9.0 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ73928.1 - 0.27 12.0 3.2 19 6.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KNZ73930.1 - 1e-24 87.6 0.5 1.4e-24 87.1 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KNZ73930.1 - 4.4e-23 80.6 0.0 9.8e-23 79.5 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 KNZ73930.1 - 6e-05 22.4 0.0 0.0035 16.7 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KNZ73930.1 - 0.0055 16.4 0.1 0.076 12.7 0.1 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF902 PF06001.13 KNZ73931.1 - 0.53 10.8 2.2 7.1 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF902) UPF0029 PF01205.19 KNZ73932.1 - 1.4e-18 67.1 0.1 1.6e-18 67.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Glucosamine_iso PF01182.20 KNZ73933.1 - 8.5e-17 61.8 0.0 1.7e-16 60.8 0.0 1.5 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 KNZ73933.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD-binding domain Glyco_hydro_15 PF00723.21 KNZ73934.1 - 5.1e-95 318.9 0.1 6.1e-95 318.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KNZ73934.1 - 1.5e-29 101.8 0.4 3.6e-29 100.5 0.4 1.7 1 0 0 1 1 1 1 Starch binding domain zf-C2H2 PF00096.26 KNZ73935.1 - 2.8e-21 74.7 80.0 0.00035 20.9 0.7 11.1 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ73935.1 - 1.2e-14 53.7 67.2 0.14 13.1 0.4 11.1 11 0 0 11 11 11 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ73935.1 - 3.2e-09 36.8 0.9 2.7e-07 30.7 0.4 12.0 12 1 1 13 13 13 3 Zinc-finger double domain zf-C2H2_8 PF15909.5 KNZ73935.1 - 5.7e-05 23.3 29.2 0.003 17.8 4.9 5.9 3 2 4 7 7 7 5 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KNZ73935.1 - 0.031 14.5 28.6 1 9.7 1.0 7.4 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KNZ73935.1 - 0.068 13.2 34.3 0.97 9.5 2.0 8.2 8 0 0 8 8 8 0 C2H2-type zinc finger zf_ZIC PF18366.1 KNZ73935.1 - 7.8 6.7 0.0 7.8 6.7 0.0 6.7 5 2 3 8 8 8 0 Zic proteins zinc finger domain Pro_CA PF00484.19 KNZ73937.1 - 4.7e-23 82.2 0.0 6e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase UPF0137 PF03677.13 KNZ73937.1 - 0.049 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) DUF2407_C PF13373.6 KNZ73938.1 - 1.2e-21 77.4 7.7 1.4e-18 67.4 1.1 3.2 3 1 0 3 3 3 2 DUF2407 C-terminal domain DUF2407 PF10302.9 KNZ73938.1 - 5.9e-19 68.6 0.1 1e-18 67.8 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KNZ73938.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family AI-2E_transport PF01594.16 KNZ73938.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 AI-2E family transporter VIT1 PF01988.19 KNZ73938.1 - 0.084 12.7 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 VIT family GIT_SHD PF08518.11 KNZ73939.1 - 4.8e-28 96.4 4.5 4.8e-15 54.9 0.7 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Exonuc_VII_L PF02601.15 KNZ73939.1 - 0.13 11.8 9.1 0.028 14.0 1.5 3.1 3 1 0 3 3 3 0 Exonuclease VII, large subunit SpecificRecomb PF10136.9 KNZ73939.1 - 2.6 6.3 11.6 0.44 8.8 2.9 2.5 3 0 0 3 3 3 0 Site-specific recombinase adh_short PF00106.25 KNZ73940.1 - 3.9e-39 134.1 1.3 5.6e-39 133.6 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ73940.1 - 6.8e-23 81.4 0.4 9.1e-23 81.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ73940.1 - 4.4e-05 23.5 0.2 7e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KNZ73940.1 - 0.0086 15.5 0.0 0.086 12.2 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) SAM_MT PF04445.13 KNZ73940.1 - 0.085 12.3 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Pyr_redox_2 PF07992.14 KNZ73940.1 - 0.098 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyridoxal_deC PF00282.19 KNZ73941.1 - 4.8e-102 341.5 0.0 5.7e-102 341.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 KNZ73941.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 KNZ73941.1 - 0.016 13.9 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 KNZ73941.1 - 0.11 11.7 0.0 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II PEX-1N PF09262.11 KNZ73942.1 - 8.9e-25 86.9 1.1 1.9e-24 85.9 0.4 2.0 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA PF00004.29 KNZ73942.1 - 2e-14 54.1 0.4 3e-11 43.9 0.0 3.7 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ73942.1 - 9.8e-11 41.3 0.5 9.9e-08 31.7 0.1 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KNZ73942.1 - 4.5e-05 23.9 0.9 0.00023 21.6 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KNZ73942.1 - 0.00074 19.5 0.0 0.0049 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KNZ73942.1 - 0.0031 17.8 0.5 0.062 13.6 0.3 3.0 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KNZ73942.1 - 0.0062 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 KNZ73942.1 - 0.015 15.2 1.6 0.7 9.8 1.6 2.4 1 1 0 1 1 1 0 NACHT domain TIP49 PF06068.13 KNZ73942.1 - 0.017 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain APS_kinase PF01583.20 KNZ73942.1 - 0.021 14.7 0.0 0.062 13.2 0.1 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase Molydop_binding PF01568.21 KNZ73942.1 - 0.029 14.4 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Sigma54_activat PF00158.26 KNZ73942.1 - 0.047 13.4 0.0 0.099 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KNZ73942.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 KNZ73942.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ73942.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 KNZ73942.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 KNZ73942.1 - 0.16 11.9 0.1 0.47 10.5 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KNZ73942.1 - 0.17 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 KNZ73942.1 - 0.17 11.0 0.0 0.36 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 KNZ73942.1 - 0.2 11.7 0.0 0.65 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNase_P_p30 PF01876.16 KNZ73943.1 - 1e-31 110.1 0.0 1.7e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Polyketide_cyc2 PF10604.9 KNZ73944.1 - 2.6e-05 24.5 0.6 9.3e-05 22.7 0.6 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KNZ73944.1 - 0.039 14.2 0.4 0.051 13.8 0.4 1.6 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport GST_N_3 PF13417.6 KNZ73945.1 - 1.9e-19 69.9 0.0 3.9e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ73945.1 - 1.2e-17 64.0 0.0 2.2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KNZ73945.1 - 7.3e-13 48.7 0.5 3.7e-12 46.4 0.2 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ73945.1 - 7.2e-06 25.9 0.0 1.8e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ73945.1 - 2e-05 24.7 0.2 0.0001 22.4 0.1 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KNZ73945.1 - 0.00038 21.0 0.0 0.00084 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TetR_C_6 PF13977.6 KNZ73945.1 - 0.078 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal GST_N_4 PF17172.4 KNZ73945.1 - 0.12 13.1 0.0 0.24 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Foie-gras_1 PF11817.8 KNZ73946.1 - 5.8e-38 131.0 0.9 7.6e-35 120.7 0.2 3.0 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 KNZ73946.1 - 2.2e-10 40.0 0.0 6.9e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 KNZ73946.1 - 3.3e-05 23.8 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 KNZ73946.1 - 0.00048 20.4 3.2 0.0044 17.3 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TRAPPC10 PF12584.8 KNZ73946.1 - 0.027 14.2 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_1 PF00515.28 KNZ73946.1 - 0.072 12.9 8.3 0.29 11.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ73946.1 - 0.14 12.4 0.2 0.89 9.9 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ73946.1 - 0.35 11.0 2.3 0.92 9.7 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73946.1 - 8 6.9 12.0 0.38 11.0 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ubiquitin PF00240.23 KNZ73947.1 - 2.5e-07 30.4 0.5 1.2e-06 28.2 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 KNZ73947.1 - 4.7e-06 27.0 0.3 2.1e-05 24.9 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain RAWUL PF16207.5 KNZ73947.1 - 0.0094 16.6 0.0 0.011 16.4 0.0 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Ubiquitin_4 PF18036.1 KNZ73947.1 - 0.043 13.9 0.2 0.62 10.1 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain SUR7 PF06687.12 KNZ73948.1 - 3.6e-07 30.0 4.2 4.4e-07 29.7 4.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Clostridium_P47 PF06597.11 KNZ73948.1 - 0.38 9.4 5.4 0.43 9.3 5.4 1.1 1 0 0 1 1 1 0 Clostridium P-47 protein Vma12 PF11712.8 KNZ73948.1 - 0.6 10.2 3.8 0.72 9.9 3.8 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Phage_holin_2_4 PF16082.5 KNZ73948.1 - 1.3 8.8 4.8 2.6 7.9 4.8 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3112 PF11309.8 KNZ73949.1 - 0.077 12.4 1.3 0.19 11.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) PalH PF08733.10 KNZ73949.1 - 6.4 5.7 14.6 54 2.6 14.5 2.0 1 1 0 1 1 1 0 PalH/RIM21 NUDIX PF00293.28 KNZ73950.1 - 2.2e-17 63.3 0.0 4.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 KNZ73950.1 - 7.8e-08 32.9 0.1 1.8e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 KNZ73950.1 - 0.0014 18.2 1.3 0.0027 17.3 1.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain ABC_membrane PF00664.23 KNZ73951.1 - 1.1e-50 172.8 0.8 1.7e-50 172.2 0.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ73951.1 - 1.5e-30 106.5 0.0 6.5e-30 104.4 0.0 2.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KNZ73951.1 - 1.4e-05 24.7 0.3 0.0005 19.6 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KNZ73951.1 - 0.016 15.6 2.4 0.064 13.6 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KNZ73951.1 - 0.091 12.8 4.0 0.77 9.8 0.0 2.9 2 1 0 2 2 2 0 Helicase HerA, central domain Hydrolase_4 PF12146.8 KNZ73952.1 - 2e-59 200.8 0.0 2.6e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ73952.1 - 1.8e-15 58.2 0.0 2.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ73952.1 - 1.8e-11 44.2 0.0 5e-08 32.9 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.10 KNZ73952.1 - 0.0029 16.7 0.2 0.0064 15.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 KNZ73952.1 - 0.0062 16.0 0.1 0.091 12.2 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KNZ73952.1 - 0.033 14.0 0.6 5 6.9 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Tannase PF07519.11 KNZ73952.1 - 0.087 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase FSH1 PF03959.13 KNZ73952.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Clathrin_lg_ch PF01086.17 KNZ73953.1 - 1.9e-41 142.6 1.9 2.2e-41 142.4 1.9 1.1 1 0 0 1 1 1 1 Clathrin light chain DUF4552 PF15089.6 KNZ73953.1 - 0.0023 17.1 0.8 0.069 12.2 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4552) Endonuc_Holl PF10107.9 KNZ73953.1 - 0.27 11.1 3.2 0.41 10.5 3.2 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase PGP_phosphatase PF09419.10 KNZ73954.1 - 1.1e-33 116.2 0.0 1.8e-18 66.7 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial PGP phosphatase Glyco_hydro_28 PF00295.17 KNZ73955.1 - 2e-60 204.5 9.1 3.5e-60 203.8 9.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 TMEM223 PF14640.6 KNZ73956.1 - 0.013 15.6 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 223 BTB PF00651.31 KNZ73957.1 - 0.00011 22.3 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-MYND PF01753.18 KNZ73957.1 - 0.045 13.9 1.8 0.079 13.1 1.8 1.4 1 0 0 1 1 1 0 MYND finger Kri1_C PF12936.7 KNZ73960.1 - 2.3e-24 85.4 0.3 2.3e-24 85.4 0.3 4.6 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 KNZ73960.1 - 6e-23 81.4 9.2 6e-23 81.4 9.2 6.4 6 2 1 7 7 7 1 KRI1-like family RNase_H PF00075.24 KNZ73963.1 - 1.4e-06 28.6 0.0 2.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ73963.1 - 0.00074 20.2 2.3 0.00074 20.2 2.3 2.4 3 0 0 3 3 3 1 zinc-binding in reverse transcriptase Pantoate_transf PF02548.15 KNZ73964.1 - 2.8e-101 338.3 0.0 3.2e-101 338.1 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KNZ73964.1 - 0.002 17.6 0.1 0.0041 16.6 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase SCP2_2 PF13530.6 KNZ73964.1 - 0.11 12.9 0.0 0.55 10.7 0.0 2.1 3 0 0 3 3 3 0 Sterol carrier protein domain PIF1 PF05970.14 KNZ73965.1 - 1.4e-23 83.7 0.0 2.1e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ73965.1 - 0.019 15.4 0.0 0.049 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ73965.1 - 0.039 13.7 0.2 0.059 13.1 0.2 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ73965.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit XPA_N PF01286.18 KNZ73965.1 - 1.4 9.0 0.1 1.4 9.0 0.1 2.6 3 0 0 3 3 3 0 XPA protein N-terminal RT_RNaseH PF17917.1 KNZ73967.1 - 3.5e-07 30.4 0.0 8.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ73967.1 - 3.4e-06 27.0 0.0 6.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIF1 PF05970.14 KNZ73968.1 - 5.4e-11 42.3 0.0 6e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ73968.1 - 0.00031 21.2 0.0 0.00042 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ73968.1 - 0.0024 17.9 0.0 0.0026 17.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2791 PF10923.8 KNZ73968.1 - 0.012 14.5 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_25 PF13481.6 KNZ73968.1 - 0.014 15.0 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KNZ73968.1 - 0.022 14.2 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein Viral_helicase1 PF01443.18 KNZ73968.1 - 0.041 13.6 0.3 0.067 12.9 0.3 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ73968.1 - 0.047 14.1 0.1 0.1 13.0 0.0 1.5 2 0 0 2 2 2 0 RNA helicase Med29 PF11568.8 KNZ73968.1 - 0.082 13.1 0.2 0.097 12.9 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 AAA PF00004.29 KNZ73968.1 - 0.093 13.2 1.0 3.6 8.0 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KNZ73968.1 - 0.098 11.8 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain GnHR_trans PF12369.8 KNZ73969.1 - 0.069 14.0 0.1 0.16 12.8 0.1 1.6 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region USP7_ICP0_bdg PF12436.8 KNZ73969.1 - 0.087 12.1 0.1 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 ICP0-binding domain of Ubiquitin-specific protease 7 Peptidase_S10 PF00450.22 KNZ73972.1 - 2.6e-72 244.5 3.3 1.2e-71 242.3 3.3 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase IGPS PF00218.21 KNZ73973.1 - 3.1e-88 295.2 0.0 6e-88 294.3 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 KNZ73973.1 - 1.4e-41 142.4 0.0 2.6e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 KNZ73973.1 - 1.3e-37 129.5 0.0 6.5e-32 110.9 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 KNZ73973.1 - 5.2e-06 26.4 0.1 4.7e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 Peptidase C26 His_biosynth PF00977.21 KNZ73973.1 - 0.015 14.8 0.0 0.47 9.9 0.0 2.5 2 0 0 2 2 2 0 Histidine biosynthesis protein QRPTase_C PF01729.19 KNZ73973.1 - 0.023 14.5 0.1 1.5 8.6 0.0 3.1 4 0 0 4 4 4 0 Quinolinate phosphoribosyl transferase, C-terminal domain TMP-TENI PF02581.17 KNZ73973.1 - 0.16 11.3 0.2 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase Pkinase PF00069.25 KNZ73974.1 - 2.4e-64 217.2 0.0 3e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ73974.1 - 1e-26 93.8 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ73974.1 - 0.019 13.9 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 KNZ73974.1 - 0.028 15.3 0.0 0.073 14.0 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat APH PF01636.23 KNZ73974.1 - 0.058 13.3 0.5 0.19 11.6 0.3 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Tetraspanin PF00335.20 KNZ73975.1 - 3.2e-05 23.8 13.8 5.5e-05 23.0 13.7 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF2981 PF11200.8 KNZ73975.1 - 0.017 14.9 5.2 0.023 14.4 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Yip1 PF04893.17 KNZ73975.1 - 0.017 14.8 14.6 0.025 14.3 14.6 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4293 PF14126.6 KNZ73975.1 - 0.28 11.4 11.0 0.2 11.9 4.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF996 PF06195.13 KNZ73975.1 - 0.48 10.7 13.7 0.081 13.2 6.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF996) MFS_1 PF07690.16 KNZ73975.1 - 4.4 6.1 17.0 12 4.7 16.8 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF2070 PF09843.9 KNZ73975.1 - 5.8 5.1 11.1 7.1 4.8 11.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PhoLip_ATPase_C PF16212.5 KNZ73976.1 - 2e-81 273.4 24.4 2e-81 273.4 24.4 1.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KNZ73976.1 - 1.1e-26 92.3 4.8 5.1e-26 90.1 4.8 2.2 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KNZ73976.1 - 2.4e-11 43.6 0.0 9e-11 41.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KNZ73976.1 - 1.4e-10 41.8 1.9 1.7e-05 25.2 0.5 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KNZ73976.1 - 4.4e-06 26.3 0.0 1.5e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KNZ73976.1 - 0.0056 16.4 0.1 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_III_psi PF03603.13 KNZ73976.1 - 0.086 13.1 0.1 0.25 11.6 0.1 1.8 1 0 0 1 1 1 0 DNA polymerase III psi subunit rve PF00665.26 KNZ73979.1 - 0.0044 17.2 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain POT1PC PF16686.5 KNZ73979.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Hist_deacetyl PF00850.19 KNZ73981.1 - 3.3e-59 200.9 0.0 4e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Sugar_tr PF00083.24 KNZ73982.1 - 4.8e-46 157.5 19.4 2.9e-45 155.0 19.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ73982.1 - 4e-21 75.3 26.2 6.9e-21 74.5 26.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily tRNA_synt_1c_R1 PF04558.15 KNZ73985.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Vps16_C PF04840.12 KNZ73986.1 - 1e-80 271.2 0.0 1.3e-80 270.8 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 KNZ73986.1 - 1.9e-75 254.2 0.0 2.6e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region tRNA-synt_1d PF00750.19 KNZ73989.1 - 1.3e-105 353.2 5.5 1.8e-105 352.7 5.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KNZ73989.1 - 2.6e-12 47.0 0.0 6.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain PAS_6 PF08348.11 KNZ73989.1 - 0.073 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 YheO-like PAS domain RRM_1 PF00076.22 KNZ73990.1 - 3.9e-39 132.3 0.1 2e-19 69.2 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ73990.1 - 4.1e-06 26.8 0.1 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 KNZ73990.1 - 0.031 14.1 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif GDI PF00996.18 KNZ73991.1 - 5.7e-43 147.0 0.0 7.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KNZ73991.1 - 4e-06 27.0 0.0 9.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KNZ73991.1 - 0.01 15.0 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KNZ73991.1 - 0.023 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KNZ73991.1 - 0.056 12.5 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KNZ73991.1 - 0.22 10.7 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ73991.1 - 0.25 10.3 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KNZ73991.1 - 0.25 10.5 0.5 0.55 9.4 0.2 1.6 2 0 0 2 2 2 0 Thi4 family S36_mt PF10937.8 KNZ73993.1 - 2.9e-09 38.5 5.3 1.8e-05 26.3 1.2 2.2 1 1 1 2 2 2 2 Ribosomal protein S36, mitochondrial CTK3 PF12243.8 KNZ73993.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Proteasome PF00227.26 KNZ73994.1 - 2e-46 157.9 0.2 8.9e-46 155.8 0.2 1.8 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KNZ73994.1 - 1e-14 53.8 0.3 2.1e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_1 PF04997.12 KNZ73995.1 - 2.8e-85 286.4 0.0 5.4e-85 285.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KNZ73995.1 - 9.1e-82 274.5 0.2 1.4e-81 273.8 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KNZ73995.1 - 4.5e-73 244.9 0.0 1.4e-72 243.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KNZ73995.1 - 8.5e-33 113.5 0.2 1.6e-31 109.4 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KNZ73995.1 - 1.6e-32 111.6 0.2 5.8e-32 109.8 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.8 KNZ73995.1 - 0.63 10.0 2.5 0.7 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) TPR_1 PF00515.28 KNZ73996.1 - 3e-09 36.3 2.2 2.5e-05 23.9 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ73996.1 - 6.7e-07 29.6 0.2 0.0011 19.6 0.0 7.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ73996.1 - 9.2e-07 28.5 21.1 0.00013 21.8 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ73996.1 - 7.3e-06 25.8 6.2 0.00051 20.0 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ73996.1 - 7.8e-05 22.8 7.3 3.7 8.1 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ73996.1 - 0.0023 17.6 0.2 0.0023 17.6 0.2 5.2 5 1 1 6 6 6 1 TPR repeat TPR_15 PF13429.6 KNZ73996.1 - 0.019 14.2 2.4 0.023 13.9 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ73996.1 - 0.023 14.9 7.3 1 9.7 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AKNA PF12443.8 KNZ73996.1 - 0.18 12.5 0.9 0.71 10.6 0.9 2.0 1 0 0 1 1 1 0 AT-hook-containing transcription factor TPR_16 PF13432.6 KNZ73996.1 - 0.21 12.2 0.0 0.21 12.2 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ73996.1 - 5.2 7.4 15.3 6.9 7.0 0.5 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Patatin PF01734.22 KNZ73998.1 - 8.4e-17 62.0 0.0 1.7e-16 61.0 0.0 1.4 1 1 0 1 1 1 1 Patatin-like phospholipase SPT2 PF08243.11 KNZ73999.1 - 9.1 6.9 8.0 17 6.0 8.0 1.4 1 1 0 1 1 1 0 SPT2 chromatin protein Med13_C PF06333.12 KNZ74001.1 - 2.8e-58 197.8 3.0 2.8e-58 197.8 3.0 3.7 4 0 0 4 4 4 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 KNZ74001.1 - 5.6e-39 134.4 2.0 5.6e-39 134.4 2.0 2.6 3 0 0 3 3 3 1 Mediator complex subunit 13 N-terminal DUF2433 PF10360.9 KNZ74002.1 - 3.8e-42 143.3 0.0 1.4e-41 141.5 0.0 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF2433) Rrn6 PF10214.9 KNZ74002.1 - 0.032 12.7 5.7 0.055 12.0 5.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRM_1 PF00076.22 KNZ74002.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 KNZ74002.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Tim54 PF11711.8 KNZ74002.1 - 0.28 9.9 5.7 0.46 9.2 5.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 KNZ74002.1 - 0.29 9.9 1.3 0.4 9.4 1.3 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KNZ74002.1 - 0.44 10.3 6.3 0.7 9.7 6.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KNZ74002.1 - 0.46 10.5 17.5 0.88 9.6 17.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 KNZ74002.1 - 0.52 10.6 11.8 0.91 9.8 11.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CPSF100_C PF13299.6 KNZ74002.1 - 0.76 9.9 5.6 1.5 9.0 5.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PNISR PF15996.5 KNZ74002.1 - 0.76 10.0 15.4 1.5 9.1 15.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RNA_pol_Rpc4 PF05132.14 KNZ74002.1 - 0.9 10.0 9.6 2.2 8.7 9.6 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 KNZ74002.1 - 1.3 7.8 14.9 2 7.2 14.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ferlin_C PF16165.5 KNZ74002.1 - 1.5 8.7 4.9 3.3 7.7 4.9 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Med3 PF11593.8 KNZ74002.1 - 3.1 6.9 17.0 5.5 6.1 17.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F_bP_aldolase PF01116.20 KNZ74003.1 - 3e-90 302.5 0.0 3.7e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.11 KNZ74003.1 - 0.046 13.8 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Torsin PPR_1 PF12854.7 KNZ74005.1 - 0.36 10.6 0.9 0.7 9.7 0.9 1.5 1 0 0 1 1 1 0 PPR repeat DUF4774 PF15999.5 KNZ74005.1 - 2.3 8.1 9.5 1.3 8.9 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4774) tRNA-synt_1 PF00133.22 KNZ74006.1 - 7e-214 711.5 0.0 4.9e-213 708.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) CRIM PF16978.5 KNZ74006.1 - 6.8e-44 149.4 0.0 1.6e-43 148.2 0.0 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain Anticodon_1 PF08264.13 KNZ74006.1 - 2.1e-34 118.7 0.3 5.5e-34 117.3 0.3 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA SIN1_PH PF16979.5 KNZ74006.1 - 5.2e-32 110.4 0.1 1e-31 109.5 0.1 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology tRNA-synt_1g PF09334.11 KNZ74006.1 - 2.1e-13 49.8 0.2 3e-07 29.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KNZ74006.1 - 4.2e-10 39.5 0.1 5.7e-07 29.2 0.1 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 TUG-UBL1 PF11470.8 KNZ74006.1 - 0.00053 20.2 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KNZ74006.1 - 0.0027 17.8 0.0 0.0097 16.0 0.0 2.0 1 0 0 1 1 1 1 Raf-like Ras-binding domain tRNA-synt_1e PF01406.19 KNZ74006.1 - 0.15 11.4 0.0 0.56 9.5 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pox_Ag35 PF03286.14 KNZ74006.1 - 0.83 9.4 7.5 1.8 8.3 7.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_L5_C PF00673.21 KNZ74007.1 - 5.8e-26 90.5 0.0 9.1e-26 89.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KNZ74007.1 - 0.0062 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 CRAL_TRIO PF00650.20 KNZ74008.1 - 3e-33 114.8 0.0 4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ74008.1 - 1.2e-10 41.4 1.2 1.2e-10 41.4 1.2 1.7 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 KNZ74009.1 - 4.1e-34 117.6 0.0 6.6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ74009.1 - 1.1e-09 38.4 0.5 2.8e-09 37.0 0.5 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KNZ74009.1 - 0.0014 18.8 0.0 0.0072 16.5 0.0 1.9 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 KNZ74009.1 - 0.16 12.2 0.2 0.56 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) Abhydrolase_1 PF00561.20 KNZ74010.1 - 8.7e-15 55.1 0.1 1.2e-13 51.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ74010.1 - 1.6e-11 45.2 0.0 2.1e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ74010.1 - 2e-09 37.1 0.0 3.2e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KNZ74010.1 - 0.0013 18.2 0.1 0.47 9.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 KNZ74010.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.7 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_4 PF08386.10 KNZ74010.1 - 0.021 15.0 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.13 KNZ74010.1 - 0.031 14.1 0.0 0.22 11.3 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold HSF_DNA-bind PF00447.17 KNZ74010.1 - 0.047 14.3 0.0 0.096 13.3 0.0 1.5 1 0 0 1 1 1 0 HSF-type DNA-binding DUF2048 PF09752.9 KNZ74010.1 - 0.095 11.8 0.1 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 YjcZ_2 PF09680.10 KNZ74012.1 - 1.9 8.2 5.5 3.2 7.5 5.5 1.3 1 0 0 1 1 1 0 Family of unknown function Plant_NMP1 PF06694.11 KNZ74013.1 - 0.14 11.3 0.0 0.19 10.8 0.0 1.3 1 1 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) GMC_oxred_C PF05199.13 KNZ74015.1 - 5.8e-37 127.4 0.0 7.4e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase AMP-binding PF00501.28 KNZ74016.1 - 3.3e-16 58.9 0.0 1e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme DnaJ PF00226.31 KNZ74019.1 - 1.7e-15 56.8 2.3 1e-14 54.4 2.3 2.4 1 1 0 1 1 1 1 DnaJ domain Borrelia_P83 PF05262.11 KNZ74019.1 - 0.004 15.7 18.3 0.0054 15.3 18.3 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein Paf1 PF03985.13 KNZ74019.1 - 2.8 6.8 24.9 3.2 6.7 24.0 1.5 1 1 0 1 1 1 0 Paf1 zf-CCHC PF00098.23 KNZ74020.1 - 0.16 12.1 1.5 0.16 12.1 1.5 2.3 3 0 0 3 3 3 0 Zinc knuckle RNase_H PF00075.24 KNZ74022.1 - 0.00055 20.1 1.1 0.0017 18.5 1.1 2.0 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ74023.1 - 0.011 16.4 0.4 0.011 16.4 0.4 1.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ74023.1 - 1 9.4 5.4 0.11 12.5 1.0 1.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PTCB-BRCT PF12738.7 KNZ74024.1 - 1.8e-28 98.2 6.1 1.2e-17 63.5 0.1 5.5 6 0 0 6 6 6 3 twin BRCT domain BRCT PF00533.26 KNZ74024.1 - 2.9e-23 82.0 0.1 1.3e-08 35.1 0.0 6.0 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KNZ74024.1 - 3.7e-20 72.1 0.0 0.00088 19.6 0.0 6.5 6 0 0 6 6 6 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 KNZ74024.1 - 1.1e-17 63.8 0.1 1.7e-16 59.9 0.0 2.9 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KNZ74024.1 - 1.1e-05 25.7 1.9 0.98 9.8 0.0 4.3 5 0 0 5 5 5 2 DNA ligase 3 BRCT domain DUF4653 PF15546.6 KNZ74025.1 - 0.24 11.0 0.0 0.33 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) RRM_1 PF00076.22 KNZ74026.1 - 8.8e-29 99.1 2.2 3.9e-09 36.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KNZ74026.1 - 0.00015 21.7 0.1 0.34 11.0 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 KNZ74026.1 - 0.00018 21.3 0.0 6.5 6.7 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KNZ74026.1 - 0.024 14.7 0.0 0.82 9.8 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif NID PF07292.13 KNZ74026.1 - 0.032 14.9 0.0 13 6.5 0.0 3.6 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Glyco_hydro81C PF17652.1 KNZ74027.1 - 1.7e-68 231.5 1.6 2.8e-68 230.7 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KNZ74027.1 - 3.2e-31 108.7 2.9 3.2e-31 108.7 2.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 KNZ74027.1 - 0.025 14.8 0.0 0.2 11.9 0.0 2.1 1 1 1 2 2 2 0 Fascin domain VHL PF01847.16 KNZ74028.1 - 0.00014 21.7 0.0 0.00076 19.4 0.0 2.0 2 0 0 2 2 2 1 VHL beta domain Metallophos PF00149.28 KNZ74029.1 - 4.1e-14 53.5 3.2 6.5e-14 52.9 2.8 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 KNZ74029.1 - 0.03 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Clat_adaptor_s PF01217.20 KNZ74031.1 - 3.4e-12 46.5 0.0 5.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 KNZ74032.1 - 2.7e-11 43.3 0.0 4e-09 36.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74032.1 - 0.0017 17.7 0.0 0.14 11.4 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase DUF1077 PF06417.12 KNZ74033.1 - 0.052 13.6 0.0 0.052 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) SKICH PF17751.1 KNZ74033.1 - 0.059 13.9 0.0 0.074 13.6 0.0 1.2 1 0 0 1 1 1 0 SKICH domain NAD_binding_4 PF07993.12 KNZ74034.1 - 1.3e-34 119.5 0.0 2e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ74034.1 - 1e-25 90.2 0.0 2.5e-25 89.0 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KNZ74034.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KNZ74034.1 - 0.0016 18.8 0.1 0.005 17.2 0.1 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 KNZ74034.1 - 0.0057 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KNZ74034.1 - 0.0086 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 KR domain CT_A_B PF02626.15 KNZ74037.1 - 4.6e-63 213.3 0.0 7.3e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 KNZ74037.1 - 3.6e-54 183.4 0.1 6.2e-54 182.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 KNZ74037.1 - 2.2e-40 138.6 0.0 3.9e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 KNZ74037.1 - 2e-34 118.4 0.0 7e-34 116.7 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KNZ74037.1 - 8.3e-29 99.9 0.0 1.8e-28 98.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 KNZ74037.1 - 2.2e-06 27.4 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 KNZ74037.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 KNZ74037.1 - 0.0082 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 KNZ74037.1 - 0.087 12.4 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Pkinase PF00069.25 KNZ74039.1 - 5.3e-11 42.4 0.0 2.7e-08 33.5 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74039.1 - 0.00081 18.8 0.0 0.063 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ74040.1 - 1.6e-08 34.2 0.0 1.3e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74040.1 - 0.006 15.9 0.0 0.56 9.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase NIF PF03031.18 KNZ74042.1 - 6.2e-39 133.3 0.1 1.3e-38 132.2 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF737 PF05300.11 KNZ74042.1 - 0.0028 18.0 4.6 0.0043 17.4 4.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF737) LRR_4 PF12799.7 KNZ74045.1 - 0.15 12.6 12.1 0.43 11.1 0.5 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) FCH PF00611.23 KNZ74046.1 - 5.2e-16 58.7 0.0 1.5e-15 57.2 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 KNZ74046.1 - 4.5e-10 39.0 0.1 9.2e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ74046.1 - 4.8e-09 35.9 0.1 8.8e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ74046.1 - 3.6e-05 23.3 0.0 6.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_C50 PF03568.17 KNZ74046.1 - 0.31 10.1 5.0 0.51 9.4 5.0 1.2 1 0 0 1 1 1 0 Peptidase family C50 Zn-ribbon_8 PF09723.10 KNZ74047.1 - 0.0017 18.4 3.2 0.0027 17.8 3.2 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zf-FPG_IleRS PF06827.14 KNZ74047.1 - 0.0039 17.0 0.5 0.009 15.9 0.5 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS zf-RRPl_C4 PF17026.5 KNZ74047.1 - 0.0054 16.8 0.6 0.007 16.4 0.6 1.3 1 0 0 1 1 1 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-UDP PF14569.6 KNZ74047.1 - 0.027 14.6 1.6 0.04 14.0 1.6 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc_ribbon_9 PF14369.6 KNZ74047.1 - 0.043 14.1 2.6 0.13 12.6 2.6 1.8 1 1 0 1 1 1 0 zinc-ribbon zinc-ribbons_6 PF07191.12 KNZ74047.1 - 0.048 13.7 1.2 0.079 13.0 1.2 1.4 1 0 0 1 1 1 0 zinc-ribbons HypA PF01155.19 KNZ74047.1 - 0.065 13.3 2.8 0.076 13.0 2.8 1.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LIM PF00412.22 KNZ74047.1 - 0.076 13.3 3.4 0.12 12.6 3.4 1.4 1 0 0 1 1 1 0 LIM domain Zn_Tnp_IS1595 PF12760.7 KNZ74047.1 - 0.086 12.8 2.2 4.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 KNZ74047.1 - 0.23 11.7 2.9 0.25 11.5 2.9 1.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DpnI PF06044.12 KNZ74047.1 - 0.29 10.7 2.4 0.32 10.6 2.4 1.3 1 1 0 1 1 1 0 Dam-replacing family zinc_ribbon_4 PF13717.6 KNZ74047.1 - 0.34 10.9 8.5 3.4 7.7 0.1 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-DNL PF05180.12 KNZ74047.1 - 2.3 8.2 5.7 8.9 6.3 5.7 1.9 1 1 0 1 1 1 0 DNL zinc finger Cys_rich_KTR PF14205.6 KNZ74047.1 - 5.5 6.9 6.5 2 8.3 0.1 2.2 1 1 0 2 2 2 0 Cysteine-rich KTR Glyco_hydr_30_2 PF14587.6 KNZ74048.1 - 1.1e-13 51.6 0.0 3.7e-10 40.0 0.0 2.1 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_cc PF11790.8 KNZ74048.1 - 0.00041 20.0 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core VHL PF01847.16 KNZ74049.1 - 5.9e-09 35.7 0.1 8.2e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 VHL beta domain Glyco_hydro81C PF17652.1 KNZ74050.1 - 4.7e-66 223.4 0.7 7e-66 222.8 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 KNZ74050.1 - 2.5e-28 99.2 2.6 2.5e-28 99.2 2.6 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Fascin PF06268.13 KNZ74050.1 - 0.021 15.0 0.0 0.16 12.2 0.0 2.1 1 1 0 1 1 1 0 Fascin domain FRG1 PF06229.12 KNZ74050.1 - 0.29 10.8 0.2 0.53 10.0 0.2 1.4 1 0 0 1 1 1 0 FRG1-like domain p450 PF00067.22 KNZ74051.1 - 7.5e-07 28.2 0.3 0.0014 17.4 0.0 2.7 3 0 0 3 3 3 2 Cytochrome P450 E1-E2_ATPase PF00122.20 KNZ74052.1 - 4.6e-50 169.6 0.3 4.6e-50 169.6 0.3 2.9 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNZ74052.1 - 1.2e-39 135.9 1.6 1.2e-39 135.9 1.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KNZ74052.1 - 2.7e-17 63.8 5.1 1.8e-16 61.1 2.8 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KNZ74052.1 - 5.2e-09 35.7 0.0 1.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KNZ74052.1 - 7.4e-09 35.6 0.1 1.5e-07 31.4 0.1 2.6 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KNZ74052.1 - 1.7e-05 24.7 1.2 0.00094 19.0 0.7 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 KNZ74052.1 - 0.001 19.0 0.2 0.005 16.8 0.0 2.3 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC RhoGEF PF00621.20 KNZ74053.1 - 1.6e-31 110.0 0.0 3.2e-31 109.0 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain TIMELESS PF04821.14 KNZ74053.1 - 0.12 11.6 0.2 0.24 10.6 0.2 1.4 1 0 0 1 1 1 0 Timeless protein Aldo_ket_red PF00248.21 KNZ74054.1 - 9e-44 149.8 0.2 4.2e-43 147.6 0.2 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family IpaB_EvcA PF03278.13 KNZ74055.1 - 0.2 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 IpaB/EvcA family UbiA PF01040.18 KNZ74064.1 - 3.8e-07 29.7 0.0 5.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-H2C2_5 PF13909.6 KNZ74065.1 - 4.2e-08 32.8 8.0 0.0009 18.9 2.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KNZ74065.1 - 4.6e-07 30.0 0.6 4.6e-07 30.0 0.6 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KNZ74065.1 - 6.1e-06 26.4 11.9 0.027 14.9 3.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ74065.1 - 0.0088 16.8 14.5 2 9.5 1.9 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger Fer2 PF00111.27 KNZ74066.1 - 2.7e-10 40.0 0.1 4.2e-10 39.4 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.25 KNZ74067.1 - 1e-28 100.1 0.1 4.4e-25 88.3 0.2 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ74067.1 - 8.9e-17 61.4 0.0 1.5e-15 57.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ74067.1 - 1.2e-06 28.6 0.1 1.6e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ74067.1 - 1.5e-06 27.9 0.0 0.013 15.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KNZ74067.1 - 0.048 12.8 0.1 0.42 9.8 0.1 2.0 1 1 0 1 1 1 0 Male sterility protein Chromo PF00385.24 KNZ74069.1 - 1.1e-14 54.0 0.0 1.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 KNZ74070.1 - 0.0059 17.2 0.0 0.0068 17.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease zf-RVT PF13966.6 KNZ74074.1 - 0.00043 21.0 0.4 0.00057 20.5 0.4 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase NAP PF00956.18 KNZ74075.1 - 2.1e-89 299.3 3.7 2.9e-89 298.9 3.7 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 KNZ74075.1 - 1.3 8.7 11.3 3.4 7.3 11.3 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 KNZ74075.1 - 4.6 6.5 9.5 7.4 5.8 9.5 1.3 1 0 0 1 1 1 0 BUD22 Cadherin_pro PF08758.11 KNZ74076.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Cadherin prodomain like LRR_4 PF12799.7 KNZ74077.1 - 0.0017 18.7 8.1 2.4 8.7 0.2 5.0 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ74077.1 - 0.36 10.6 6.8 1.3 8.9 0.3 3.4 3 0 0 3 3 3 0 Leucine rich repeat MutL_C PF08676.11 KNZ74079.1 - 8.2e-25 87.3 0.2 2.7e-24 85.6 0.2 1.9 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KNZ74079.1 - 9.8e-19 67.2 0.0 2.1e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KNZ74079.1 - 7e-11 42.1 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KNZ74079.1 - 3.8e-09 37.1 0.0 1.4e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyoxal_oxid_N PF07250.11 KNZ74080.1 - 2.4e-28 99.0 2.1 2.6e-22 79.2 3.0 5.0 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ74080.1 - 4.6e-23 81.3 1.1 1.1e-22 80.1 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KNZ74080.1 - 0.00059 19.8 3.3 0.55 10.3 0.1 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ74080.1 - 0.03 14.6 2.2 12 6.4 0.1 4.8 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 KNZ74080.1 - 0.03 14.3 0.1 12 6.1 0.0 3.8 3 0 0 3 3 3 0 Kelch motif DUF5122 PF17164.4 KNZ74080.1 - 1.9 8.9 8.5 62 4.0 0.0 5.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller Kelch_5 PF13854.6 KNZ74080.1 - 2.4 8.2 9.1 4.9 7.2 0.1 5.1 5 1 0 5 5 5 0 Kelch motif Pkinase PF00069.25 KNZ74081.1 - 2.8e-06 26.9 0.0 4.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ74082.1 - 0.00031 20.7 0.0 0.002 18.1 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ74082.1 - 0.0057 16.3 0.0 0.0072 15.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ74082.1 - 0.062 12.9 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 KNZ74083.1 - 6e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74083.1 - 0.054 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KNZ74084.1 - 2e-07 30.7 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Chitin_synth_1 PF01644.17 KNZ74085.1 - 2.2e-66 222.9 0.1 3.5e-66 222.2 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KNZ74085.1 - 4.1e-29 100.3 0.1 9.6e-29 99.2 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KNZ74085.1 - 2.3e-24 85.9 0.2 7.4e-21 74.4 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KNZ74085.1 - 1.1e-08 35.3 0.0 1.1e-08 35.3 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferase family group 2 RVT_1 PF00078.27 KNZ74086.1 - 0.00028 20.5 0.0 0.00028 20.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CRC_subunit PF08624.10 KNZ74089.1 - 7.1e-43 146.3 0.7 1.1e-42 145.7 0.0 1.6 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit AMP-binding PF00501.28 KNZ74091.1 - 3e-57 194.1 0.5 1.3e-40 139.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ74091.1 - 0.0072 17.3 0.0 0.033 15.1 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TPT PF03151.16 KNZ74092.1 - 5.5e-06 25.9 18.0 7.4e-06 25.5 18.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF4434 PF14488.6 KNZ74092.1 - 0.14 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Tetraspanin PF00335.20 KNZ74092.1 - 0.59 9.8 4.5 0.14 11.9 0.4 2.0 2 0 0 2 2 2 0 Tetraspanin family Pkinase PF00069.25 KNZ74093.1 - 6.2e-64 215.9 0.0 4.6e-63 213.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74093.1 - 1.9e-37 129.0 0.0 2.3e-36 125.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ74093.1 - 8.1e-07 28.6 0.0 2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ74093.1 - 0.00028 20.9 6.2 0.042 13.8 0.1 4.3 3 1 1 4 4 4 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ74093.1 - 0.019 13.9 0.0 0.047 12.6 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain DUF1874 PF08960.10 KNZ74093.1 - 0.42 10.8 2.4 1.2 9.3 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) Hydantoinase_B PF02538.14 KNZ74093.1 - 2.6 6.4 6.3 3.8 5.8 6.3 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF5595 PF18077.1 KNZ74093.1 - 3 8.0 4.8 2.8 8.1 0.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) DUF5082 PF16888.5 KNZ74093.1 - 3.4 8.0 14.6 4.5 7.6 1.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Peptidase_M20 PF01546.28 KNZ74094.1 - 3.5e-07 30.1 0.1 5.4e-07 29.5 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 AAA_12 PF13087.6 KNZ74095.1 - 2.2e-57 193.9 0.0 1.1e-56 191.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KNZ74095.1 - 6.6e-55 186.7 0.0 1.9e-54 185.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ74095.1 - 2.6e-10 40.5 0.0 0.044 13.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 KNZ74095.1 - 3.9e-09 37.0 0.0 5.8e-08 33.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KNZ74095.1 - 4e-09 36.5 0.0 1.4e-05 24.9 0.0 2.5 2 1 0 2 2 2 2 AAA domain ResIII PF04851.15 KNZ74095.1 - 5.3e-05 23.3 0.0 0.008 16.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNZ74095.1 - 6.9e-05 23.1 0.0 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 KNZ74095.1 - 0.0018 18.1 0.0 0.0068 16.2 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 KNZ74095.1 - 0.0024 17.4 0.0 0.0066 16.0 0.0 1.8 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 KNZ74095.1 - 0.0052 16.1 0.0 0.36 10.0 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 KNZ74095.1 - 0.019 15.4 0.0 0.088 13.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ74095.1 - 0.022 15.2 0.1 0.074 13.4 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KNZ74095.1 - 0.025 14.3 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KNZ74095.1 - 0.089 13.0 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KNZ74095.1 - 0.11 13.0 0.0 0.34 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ74095.1 - 0.12 12.0 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 KNZ74095.1 - 0.18 10.9 0.0 18 4.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase ATPase_2 PF01637.18 KNZ74096.1 - 8.6e-12 45.5 0.0 0.00016 21.6 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_16 PF13191.6 KNZ74096.1 - 3.1e-08 34.2 0.0 5.5e-07 30.1 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KNZ74096.1 - 1.2e-06 28.8 0.0 0.0089 16.3 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 KNZ74096.1 - 0.0023 18.4 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 KNZ74096.1 - 0.018 13.8 0.0 0.037 12.8 0.0 1.5 2 0 0 2 2 2 0 RNA12 protein zf-C3HC4_2 PF13923.6 KNZ74097.1 - 1.5e-07 31.1 2.8 1.5e-07 31.1 2.8 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ74097.1 - 7.5e-07 29.1 2.6 7.5e-07 29.1 2.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KNZ74097.1 - 6.6e-06 26.2 1.9 6.6e-06 26.2 1.9 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KNZ74097.1 - 3e-05 23.8 18.5 0.00014 21.7 1.5 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ74097.1 - 3.1e-05 23.7 6.9 3.1e-05 23.7 6.9 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ74097.1 - 5e-05 23.6 2.2 5e-05 23.6 2.2 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KNZ74097.1 - 0.00034 20.5 9.1 0.00034 20.5 9.1 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 KNZ74097.1 - 0.00064 19.5 0.3 0.00064 19.5 0.3 2.5 3 0 0 3 3 3 1 zf-RING of BARD1-type protein HAMP PF00672.25 KNZ74098.1 - 1.7e-45 153.1 17.1 3.1e-08 33.8 0.0 8.7 8 0 0 8 8 7 6 HAMP domain HATPase_c PF02518.26 KNZ74098.1 - 1.2e-29 103.0 0.2 3.8e-29 101.5 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KNZ74098.1 - 1.1e-22 80.3 0.1 3.4e-22 78.7 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KNZ74098.1 - 1.9e-17 63.0 1.1 1.1e-16 60.6 1.1 2.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF4795 PF16043.5 KNZ74098.1 - 7.4e-08 32.2 0.3 0.0037 16.9 0.0 4.0 2 1 1 4 4 4 2 Domain of unknown function (DUF4795) DUF3829 PF12889.7 KNZ74098.1 - 0.018 14.5 0.7 14 5.1 0.0 4.1 4 1 0 4 4 4 0 Protein of unknown function (DUF3829) DUF4279 PF14106.6 KNZ74098.1 - 0.03 14.5 0.0 14 5.9 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) DUF5609 PF18429.1 KNZ74098.1 - 0.06 13.1 1.0 1 9.2 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5609) DUF1843 PF08898.10 KNZ74098.1 - 0.31 11.6 8.9 10 6.7 0.1 6.1 7 1 0 7 7 7 0 Domain of unknown function (DUF1843) WXG100 PF06013.12 KNZ74098.1 - 0.47 10.7 15.0 5.1 7.4 0.4 6.9 5 2 5 10 10 10 0 Proteins of 100 residues with WXG SpoIIID PF12116.8 KNZ74098.1 - 0.63 10.2 3.1 66 3.7 0.0 4.8 5 0 0 5 5 5 0 Stage III sporulation protein D ATG16 PF08614.11 KNZ74098.1 - 0.7 10.1 3.6 0.91 9.7 0.2 3.0 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) T4SS PF07996.11 KNZ74098.1 - 8.9 6.7 13.2 10 6.5 0.4 3.7 3 2 1 4 4 4 0 Type IV secretion system proteins HNH_2 PF13391.6 KNZ74099.1 - 2.6e-08 33.9 0.1 9.1e-08 32.1 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease DUF3295 PF11702.8 KNZ74099.1 - 5.4 6.2 6.4 8 5.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) RNase_H PF00075.24 KNZ74100.1 - 2.9e-13 50.2 0.0 3.1e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 RNase H Glyco_hydro_3_C PF01915.22 KNZ74101.1 - 2.5e-39 135.4 0.0 3.5e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain SGL PF08450.12 KNZ74101.1 - 0.31 10.6 1.7 2.4 7.7 0.1 2.2 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF3328 PF11807.8 KNZ74103.1 - 1.4e-21 77.3 3.0 1.6e-21 77.1 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GDP_Man_Dehyd PF16363.5 KNZ74103.1 - 0.085 12.2 0.1 0.14 11.6 0.1 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase But2 PF09792.9 KNZ74104.1 - 0.002 18.5 0.0 0.0027 18.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PIF1 PF05970.14 KNZ74105.1 - 7.8e-09 35.2 0.0 8.1e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Rad1 PF02144.16 KNZ74107.1 - 7.4e-76 254.8 0.0 8.5e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF3244 PF11589.8 KNZ74108.1 - 0.12 12.4 0.4 0.18 11.9 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Asp_protease_2 PF13650.6 KNZ74110.1 - 0.00039 21.0 0.0 0.00072 20.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ74110.1 - 0.0016 19.0 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KNZ74110.1 - 0.041 13.7 0.8 1.1 9.0 0.2 2.6 1 1 2 3 3 3 0 Aspartyl protease RVP_2 PF08284.11 KNZ74111.1 - 0.037 13.8 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Cellulase PF00150.18 KNZ74112.1 - 4.3e-48 164.2 0.1 5.6e-48 163.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KNZ74112.1 - 1.7e-07 31.0 3.7 1.7e-07 31.0 3.7 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Complex1_LYR PF05347.15 KNZ74113.1 - 0.00076 19.5 0.7 0.0015 18.6 0.7 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Sec8_exocyst PF04048.14 KNZ74114.1 - 2.9e-26 92.0 0.1 4.5e-25 88.2 0.1 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 KNZ74114.1 - 0.00017 21.0 0.3 0.00036 19.9 0.3 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex LIDHydrolase PF10230.9 KNZ74115.1 - 1.6e-47 162.3 0.0 1.8e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KNZ74115.1 - 0.0014 19.3 2.8 0.0019 18.9 2.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ74115.1 - 0.0017 17.7 0.2 0.0025 17.1 0.2 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KNZ74115.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KNZ74115.1 - 0.02 14.5 0.2 0.03 14.0 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SNF2_N PF00176.23 KNZ74116.1 - 9e-54 182.5 0.1 1.3e-53 181.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ74116.1 - 3.2e-18 66.1 0.0 9.7e-18 64.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KNZ74116.1 - 2e-16 60.1 1.5 2.3e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 zf-PHD-like PF15446.6 KNZ74116.1 - 1.6e-06 27.8 6.0 1.6e-06 27.8 6.0 2.8 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain ResIII PF04851.15 KNZ74116.1 - 1.7e-06 28.1 0.0 4.8e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNZ74116.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 KNZ74116.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SRP54 PF00448.22 KNZ74116.1 - 0.15 11.7 0.0 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Chromo PF00385.24 KNZ74116.1 - 0.72 9.8 11.4 0.88 9.5 0.2 3.3 4 0 0 4 4 4 0 Chromo (CHRromatin Organisation MOdifier) domain Ribonucleas_3_3 PF14622.6 KNZ74117.1 - 8e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KNZ74117.1 - 2e-06 28.4 0.0 2e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KNZ74117.1 - 0.0081 16.8 0.0 0.018 15.7 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Pkinase PF00069.25 KNZ74118.1 - 1.3e-53 182.1 0.0 1.6e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74118.1 - 1.9e-28 99.5 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ74118.1 - 3.7e-05 23.2 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FHA PF00498.26 KNZ74118.1 - 0.0019 18.5 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KNZ74118.1 - 0.13 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metal_resist PF13801.6 KNZ74118.1 - 0.16 12.1 0.0 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Heavy-metal resistance Esterase PF00756.20 KNZ74119.1 - 3.6e-44 151.3 0.0 4.3e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KNZ74119.1 - 0.0022 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KNZ74119.1 - 0.007 15.3 0.0 0.022 13.7 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KNZ74119.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KNZ74119.1 - 0.024 14.1 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.22 KNZ74120.1 - 4.4e-24 85.1 0.0 8.4e-24 84.1 0.0 1.4 2 0 0 2 2 2 1 Cytochrome P450 Kelch_4 PF13418.6 KNZ74122.1 - 4.6e-32 109.8 7.3 1e-05 25.4 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KNZ74122.1 - 6.5e-31 105.7 7.4 8.2e-07 28.5 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KNZ74122.1 - 1e-30 105.2 6.7 0.00023 21.1 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KNZ74122.1 - 1.1e-30 104.8 6.7 7.1e-07 29.3 0.5 6.4 3 2 3 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KNZ74122.1 - 2.4e-30 104.2 10.1 9.9e-07 28.9 0.0 6.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 KNZ74122.1 - 1.9e-19 68.8 10.9 0.0047 16.9 0.1 6.5 6 0 0 6 6 6 5 Kelch motif DUF2353 PF09789.9 KNZ74122.1 - 0.00034 20.1 15.5 0.00034 20.1 15.5 4.7 1 1 5 6 6 6 1 Uncharacterized coiled-coil protein (DUF2353) IFN-gamma PF00714.17 KNZ74122.1 - 0.13 12.1 0.6 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Interferon gamma DUF4172 PF13776.6 KNZ74122.1 - 7.1 7.0 14.6 3.4 8.1 1.4 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4172) ABC_membrane_2 PF06472.15 KNZ74123.1 - 7.9e-77 258.3 0.6 1.3e-76 257.6 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KNZ74123.1 - 3.6e-16 59.9 0.0 7.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KNZ74123.1 - 0.066 12.6 0.0 3.9 6.8 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 KNZ74123.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI S1 PF00575.23 KNZ74124.1 - 5.5e-53 177.2 24.1 1.8e-13 50.6 0.2 10.6 10 0 0 10 10 10 9 S1 RNA binding domain TPR_14 PF13428.6 KNZ74124.1 - 3.8e-06 27.3 0.2 3.4 8.7 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ74124.1 - 1.6e-05 25.3 0.9 3.3 8.3 0.0 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74124.1 - 0.00011 22.7 0.0 0.13 12.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat S1_2 PF13509.6 KNZ74124.1 - 0.00084 19.4 2.0 8.3 6.6 0.0 5.4 5 0 0 5 5 5 1 S1 domain TPR_12 PF13424.6 KNZ74124.1 - 0.0011 19.2 1.2 2.1 8.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ74124.1 - 0.0037 17.5 0.1 0.014 15.6 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NRDE-2 PF08424.10 KNZ74124.1 - 0.0051 16.0 9.2 0.16 11.1 0.1 3.4 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_21 PF09976.9 KNZ74124.1 - 0.0086 15.8 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain DUF966 PF06136.13 KNZ74124.1 - 0.01 15.6 0.9 0.01 15.6 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) TPR_2 PF07719.17 KNZ74124.1 - 0.034 14.3 1.4 16 5.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Suf PF05843.14 KNZ74124.1 - 0.088 12.8 11.0 0.88 9.5 1.3 4.1 2 1 2 4 4 4 0 Suppressor of forked protein (Suf) RNA_pol_Rbc25 PF08292.12 KNZ74124.1 - 0.55 10.5 8.0 4.4 7.6 0.0 5.1 7 0 0 7 7 7 0 RNA polymerase III subunit Rpc25 DUF4798 PF16055.5 KNZ74124.1 - 1.1 9.5 5.5 0.16 12.2 0.4 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4798) Inhibitor_I69 PF13734.6 KNZ74124.1 - 1.6 9.2 4.1 2.3 8.7 0.0 2.9 3 0 0 3 3 3 0 Spi protease inhibitor SF3A2 PF16835.5 KNZ74125.1 - 7.5e-37 125.6 0.1 1.1e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KNZ74125.1 - 2e-06 28.0 0.7 2e-06 28.0 0.7 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KNZ74125.1 - 0.0085 15.6 0.9 0.016 14.7 0.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.9 KNZ74125.1 - 0.044 13.7 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein MRP-S25 PF13741.6 KNZ74126.1 - 2.6e-41 141.7 11.2 1.9e-39 135.6 11.2 2.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KNZ74126.1 - 0.035 14.4 7.7 0.16 12.3 7.7 2.0 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 IDO PF01231.18 KNZ74126.1 - 0.046 12.5 0.1 0.06 12.1 0.1 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase PCI PF01399.27 KNZ74127.1 - 7.2e-19 68.3 0.0 2.7e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KNZ74127.1 - 8e-06 25.9 1.2 2.3e-05 24.4 1.2 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain F-box-like PF12937.7 KNZ74128.1 - 0.054 13.4 0.1 0.24 11.3 0.1 2.2 1 0 0 1 1 1 0 F-box-like Drc1-Sld2 PF11719.8 KNZ74129.1 - 1.8e-12 47.6 29.7 9.1e-11 42.0 29.6 3.0 1 1 0 1 1 1 1 DNA replication and checkpoint protein DUF4148 PF13663.6 KNZ74131.1 - 1.2 9.4 2.9 0.76 10.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Pal1 PF08316.11 KNZ74132.1 - 0.016 15.9 0.7 0.036 14.8 0.0 1.9 2 0 0 2 2 2 0 Pal1 cell morphology protein AMP-binding PF00501.28 KNZ74133.1 - 2e-67 227.7 0.0 5.2e-67 226.3 0.0 1.6 1 1 1 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ74133.1 - 2.1e-12 47.8 0.2 8e-12 46.0 0.2 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Lambda_Kil PF06301.11 KNZ74133.1 - 0.12 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein PIF1 PF05970.14 KNZ74134.1 - 3.4e-38 131.8 0.4 6.5e-38 130.8 0.1 1.5 2 0 0 2 2 2 1 PIF1-like helicase ResIII PF04851.15 KNZ74134.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ74134.1 - 0.0037 17.7 0.0 0.0055 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KNZ74134.1 - 0.0049 16.6 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KNZ74134.1 - 0.0097 16.3 0.1 0.18 12.2 0.0 2.7 3 1 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 KNZ74134.1 - 0.045 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 KNZ74134.1 - 0.08 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_25 PF13481.6 KNZ74134.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KNZ74134.1 - 0.097 12.4 0.1 0.23 11.2 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase EcoEI_R_C PF08463.10 KNZ74134.1 - 0.099 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal Med7 PF05983.11 KNZ74135.1 - 1.4e-48 165.5 0.3 1.9e-48 165.1 0.3 1.2 1 0 0 1 1 1 1 MED7 protein Mod_r PF07200.13 KNZ74135.1 - 0.012 15.7 1.1 0.018 15.1 1.1 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein BCL_N PF04714.13 KNZ74136.1 - 0.00058 19.9 0.1 0.001 19.1 0.1 1.4 1 0 0 1 1 1 1 BCL7, N-terminal conserver region IL17R_fnIII_D1 PF16556.5 KNZ74136.1 - 0.0035 17.0 0.2 0.0059 16.3 0.2 1.3 1 0 0 1 1 1 1 Interleukin-17 receptor, fibronectin-III-like domain 1 GARS_A PF01071.19 KNZ74140.1 - 9.9e-79 263.6 0.0 1.5e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 KNZ74140.1 - 2.1e-32 111.7 0.0 2.3e-31 108.4 0.0 2.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 KNZ74140.1 - 1.8e-30 106.1 0.0 3.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 KNZ74140.1 - 1.2e-28 99.2 0.5 2.7e-28 98.0 0.5 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 KNZ74140.1 - 1.1e-14 54.8 3.5 2.3e-14 53.8 1.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 KNZ74140.1 - 0.00014 21.4 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 KNZ74140.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Ank_2 PF12796.7 KNZ74141.1 - 1.1e-07 32.3 0.0 2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_2 PF14608.6 KNZ74141.1 - 2.3e-07 31.0 17.1 8.8e-07 29.2 5.4 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 KNZ74141.1 - 7.3e-07 28.8 11.7 0.00019 21.1 3.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_5 PF13857.6 KNZ74141.1 - 7.8e-07 29.3 0.0 9.4e-06 25.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ74141.1 - 9.4e-06 25.6 0.0 0.00057 20.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat zf_CCCH_4 PF18345.1 KNZ74141.1 - 5.2e-05 23.1 15.3 0.00069 19.6 1.1 3.1 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 KNZ74141.1 - 7.6e-05 23.4 2.9 0.00025 21.7 0.1 2.3 2 0 0 2 2 2 1 Torus domain Ank PF00023.30 KNZ74141.1 - 0.00023 21.5 0.1 0.0019 18.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH PF00642.24 KNZ74141.1 - 0.00037 20.3 11.7 0.039 13.9 3.5 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.6 KNZ74141.1 - 0.00046 20.7 0.0 0.00094 19.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NAD_Gly3P_dh_C PF07479.14 KNZ74142.1 - 1e-50 171.7 0.3 1.6e-50 171.1 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KNZ74142.1 - 2.8e-24 85.9 0.0 7.7e-24 84.5 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SNARE PF05739.19 KNZ74143.1 - 1.1e-10 41.4 0.5 2.9e-10 40.0 0.5 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KNZ74143.1 - 6.6e-06 25.2 2.1 8e-06 24.9 0.1 2.4 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 KNZ74143.1 - 2.1e-05 24.7 3.1 2.2e-05 24.6 0.5 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.25 KNZ74143.1 - 6.6e-05 22.7 0.5 6.6e-05 22.7 0.5 2.7 2 1 1 3 3 3 1 Syntaxin DUF1351 PF07083.11 KNZ74143.1 - 0.027 14.3 1.1 0.027 14.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) BLOC1_2 PF10046.9 KNZ74143.1 - 0.16 12.3 6.3 0.31 11.4 0.6 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 KNZ74143.1 - 0.17 12.1 8.1 0.33 11.2 2.5 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein ALMT PF11744.8 KNZ74143.1 - 1 8.1 9.5 1.8 7.3 7.2 2.0 2 0 0 2 2 2 0 Aluminium activated malate transporter Cor1 PF04803.12 KNZ74143.1 - 2 8.6 9.7 2.9 8.1 1.3 2.6 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Spectrin PF00435.21 KNZ74143.1 - 3.8 8.0 8.1 0.69 10.4 0.7 3.0 2 1 1 3 3 3 0 Spectrin repeat DUF16 PF01519.16 KNZ74143.1 - 8.3 7.0 16.3 0.08 13.4 1.3 2.9 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 KNZ74143.1 - 9.7 6.3 12.0 1.6 8.8 1.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RRM_1 PF00076.22 KNZ74144.1 - 1e-07 31.7 0.0 2.5e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Protamine_P2 PF00841.19 KNZ74144.1 - 0.32 11.5 0.2 0.32 11.5 0.2 3.1 4 1 0 4 4 4 0 Sperm histone P2 Wound_ind PF08186.11 KNZ74144.1 - 7.2 7.1 11.6 1.1 9.8 0.5 3.1 2 0 0 2 2 2 0 Wound-inducible basic protein family DUF4663 PF15668.5 KNZ74145.1 - 0.73 8.8 3.8 1.5 7.8 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) MAPEG PF01124.18 KNZ74146.1 - 1.4e-18 67.1 0.2 1.6e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 MAPEG family DDE_3 PF13358.6 KNZ74147.1 - 0.0044 16.8 0.0 0.054 13.2 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease CENP-C_C PF11699.8 KNZ74148.1 - 1.3e-24 86.2 0.1 2.1e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KNZ74148.1 - 0.00035 20.2 0.0 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain TonB_N PF16031.5 KNZ74148.1 - 0.03 14.8 3.9 0.03 14.8 3.9 3.6 4 0 0 4 4 4 0 TonB polyproline region AraC_binding PF02311.19 KNZ74148.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain NOA36 PF06524.12 KNZ74148.1 - 2.7 7.2 7.4 5.6 6.2 7.4 1.5 1 0 0 1 1 1 0 NOA36 protein tRNA_Me_trans PF03054.16 KNZ74149.1 - 1.8e-112 375.6 0.0 2.1e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 KNZ74149.1 - 0.0092 15.1 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Retrotran_gag_2 PF14223.6 KNZ74150.1 - 3.1e-09 36.6 0.5 5.2e-09 35.9 0.5 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KNZ74150.1 - 0.25 11.5 1.0 0.52 10.5 1.0 1.5 1 0 0 1 1 1 0 Zinc knuckle CAF1C_H4-bd PF12265.8 KNZ74152.1 - 3.4e-14 52.9 0.1 3.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KNZ74152.1 - 1.1e-11 45.1 7.1 0.00031 21.5 0.2 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat PA28_beta PF02252.18 KNZ74153.1 - 3.6e-51 172.6 1.4 5.3e-51 172.1 1.4 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 KNZ74153.1 - 0.006 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome activator pa28 alpha subunit DUF3591 PF12157.8 KNZ74154.1 - 1.3e-187 623.9 0.3 2.1e-187 623.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 KNZ74154.1 - 0.0001 22.1 2.2 0.00024 20.9 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle TFIIF_beta PF02270.15 KNZ74154.1 - 0.0011 19.0 0.2 0.0024 18.0 0.2 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain zf-CCHC PF00098.23 KNZ74154.1 - 0.78 9.9 3.3 1.4 9.1 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.26 KNZ74155.1 - 7.7e-07 29.2 25.8 5.7e-05 23.3 2.0 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ74155.1 - 8.3e-05 22.8 3.9 8.3e-05 22.8 3.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KNZ74155.1 - 0.00099 19.3 0.7 0.00099 19.3 0.7 4.0 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ74155.1 - 0.0018 18.6 0.7 0.0018 18.6 0.7 4.1 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KNZ74155.1 - 0.0023 18.6 1.7 0.0023 18.6 1.7 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KNZ74155.1 - 0.0042 17.0 1.0 0.013 15.4 1.0 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 KNZ74155.1 - 0.19 12.0 8.2 0.52 10.6 8.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon EF-hand_6 PF13405.6 KNZ74156.1 - 1.8e-13 49.2 1.5 8.9e-07 28.4 0.4 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KNZ74156.1 - 2.8e-11 43.7 2.5 2.2e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KNZ74156.1 - 6.6e-07 28.4 7.4 0.00078 18.8 0.4 3.9 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 KNZ74156.1 - 0.0002 21.6 0.0 0.64 10.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain DUF2666 PF10869.8 KNZ74156.1 - 0.023 14.9 0.1 0.44 10.8 0.0 2.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2666) DUF1456 PF07308.13 KNZ74156.1 - 0.034 14.5 0.0 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) RRM_1 PF00076.22 KNZ74156.1 - 0.043 13.7 0.2 0.61 9.9 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_5 PF13202.6 KNZ74156.1 - 0.049 13.1 0.7 0.049 13.1 0.7 2.5 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 KNZ74156.1 - 1 9.3 7.2 2.5 8.0 0.2 3.6 3 2 1 4 4 4 0 EF-hand domain pair adh_short PF00106.25 KNZ74157.1 - 8.8e-44 149.3 0.4 1.2e-43 148.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ74157.1 - 2.2e-34 119.1 0.0 2.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KNZ74157.1 - 7.6e-08 32.1 0.0 1.1e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KNZ74157.1 - 3.3e-06 27.1 0.0 6.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ74157.1 - 8.2e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KNZ74157.1 - 0.0022 17.1 0.0 0.0041 16.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.15 KNZ74157.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PI-PLC-C1 PF16670.5 KNZ74158.1 - 0.0016 17.6 0.1 0.84 8.6 0.0 2.9 3 0 0 3 3 3 2 Phosphoinositide phospholipase C, Ca2+-dependent PI-PLC-X PF00388.19 KNZ74158.1 - 0.049 13.2 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Utp11 PF03998.13 KNZ74159.1 - 7.8e-69 232.3 27.4 1.2e-68 231.7 27.4 1.3 1 1 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KNZ74159.1 - 0.022 14.1 0.6 0.042 13.2 0.6 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Type2_restr_D3 PF16902.5 KNZ74159.1 - 0.063 13.2 0.3 0.18 11.8 0.3 1.7 1 0 0 1 1 1 0 Type-2 restriction enzyme D3 domain DsrD PF08679.11 KNZ74159.1 - 0.077 13.3 1.4 0.32 11.3 0.1 2.5 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Pex14_N PF04695.13 KNZ74160.1 - 1.1 9.9 16.4 0.087 13.5 10.6 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VHS PF00790.19 KNZ74161.1 - 1e-29 103.2 0.0 2.2e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 KNZ74161.1 - 1.3e-08 35.0 0.2 9.8e-08 32.2 0.3 2.3 2 0 0 2 2 2 1 GAT domain Penicillinase_R PF03965.16 KNZ74161.1 - 0.012 15.9 0.9 0.44 10.9 0.0 2.6 2 0 0 2 2 2 0 Penicillinase repressor KIF1B PF12423.8 KNZ74161.1 - 0.14 12.6 0.5 0.67 10.4 0.1 2.4 2 0 0 2 2 2 0 Kinesin protein 1B MnmE_helical PF12631.7 KNZ74161.1 - 1.2 9.3 7.0 3 8.0 7.0 1.8 1 1 0 1 1 1 0 MnmE helical domain tRNA-synt_2b PF00587.25 KNZ74162.1 - 5.8e-21 75.3 0.0 1.3e-20 74.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KNZ74162.1 - 9.2e-08 32.3 0.8 1.5e-07 31.6 0.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Rep_fac_C PF08542.11 KNZ74163.1 - 1.7e-26 92.4 0.0 3.7e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KNZ74163.1 - 2.5e-12 46.9 0.1 2.7e-10 40.3 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 KNZ74163.1 - 5.5e-12 46.3 0.0 9.5e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KNZ74163.1 - 7e-07 29.3 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ74163.1 - 1.1e-06 29.2 0.0 6.5e-05 23.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KNZ74163.1 - 5.5e-06 26.7 0.0 0.0015 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KNZ74163.1 - 4e-05 23.5 0.0 6.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNZ74163.1 - 5.6e-05 22.9 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 KNZ74163.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 KNZ74163.1 - 0.0033 16.8 0.0 0.033 13.5 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MeaB PF03308.16 KNZ74163.1 - 0.0034 16.4 0.0 0.0068 15.4 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 KNZ74163.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain NTPase_1 PF03266.15 KNZ74163.1 - 0.0078 16.1 0.1 0.022 14.6 0.1 1.7 1 1 1 2 2 2 1 NTPase AAA_11 PF13086.6 KNZ74163.1 - 0.0099 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KNZ74163.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KNZ74163.1 - 0.032 14.6 0.1 0.21 12.0 0.1 2.4 1 1 0 1 1 1 0 RNA helicase AAA_assoc_2 PF16193.5 KNZ74163.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_19 PF13245.6 KNZ74163.1 - 0.057 13.8 0.2 0.32 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KNZ74163.1 - 0.085 13.4 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KNZ74163.1 - 0.094 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KNZ74163.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ74163.1 - 0.17 11.6 0.1 0.38 10.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KNZ74163.1 - 0.17 12.4 0.0 0.4 11.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PIF1 PF05970.14 KNZ74165.1 - 2.1e-15 56.8 0.0 2.9e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ74165.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ74165.1 - 0.0053 17.2 0.0 0.008 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KNZ74165.1 - 0.063 13.0 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Med29 PF11568.8 KNZ74165.1 - 0.066 13.4 0.5 0.099 12.9 0.5 1.3 1 1 0 1 1 1 0 Mediator complex subunit 29 DUF2791 PF10923.8 KNZ74165.1 - 0.077 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.18 KNZ74165.1 - 0.083 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sdh5 PF03937.16 KNZ74165.1 - 0.09 12.8 0.1 0.39 10.7 0.0 1.9 1 1 1 2 2 2 0 Flavinator of succinate dehydrogenase Torsin PF06309.11 KNZ74165.1 - 0.13 12.3 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Torsin DinB_2 PF12867.7 KNZ74166.1 - 0.00015 22.2 1.0 0.00018 22.0 1.0 1.1 1 0 0 1 1 1 1 DinB superfamily Chromo PF00385.24 KNZ74167.1 - 1.3e-06 28.2 0.1 4e-06 26.6 0.1 1.9 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Fungal_KA1 PF16797.5 KNZ74167.1 - 0.15 11.8 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 Fungal kinase associated-1 domain 4HBT_3 PF13622.6 KNZ74168.1 - 8.4e-51 173.6 0.1 1.1e-50 173.3 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KNZ74168.1 - 1.4e-18 67.0 0.1 9.7e-14 51.3 0.0 3.4 2 2 0 2 2 2 2 Acyl-CoA thioesterase EB_dh PF09459.10 KNZ74168.1 - 0.018 15.0 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Ribosomal_S27e PF01667.17 KNZ74169.1 - 1.6e-22 78.9 4.9 1.8e-22 78.8 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_12 PF11331.8 KNZ74169.1 - 0.64 9.9 7.3 6.1 6.7 5.8 2.6 1 1 1 2 2 2 0 Probable zinc-ribbon domain BTG PF07742.12 KNZ74170.1 - 1.7e-11 44.0 0.0 3e-09 36.7 0.0 2.4 3 0 0 3 3 3 2 BTG family QWRF PF04484.12 KNZ74170.1 - 0.042 13.6 5.0 0.059 13.1 5.0 1.2 1 0 0 1 1 1 0 QWRF family CCDC106 PF15794.5 KNZ74170.1 - 0.076 12.7 3.3 0.12 12.0 3.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Macoilin PF09726.9 KNZ74170.1 - 0.42 9.1 3.0 0.54 8.7 3.0 1.0 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 KNZ74170.1 - 0.72 8.1 6.1 0.93 7.7 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EBP50_C PF09007.11 KNZ74170.1 - 1.2 10.1 10.8 2.9 8.9 10.8 1.7 1 1 0 1 1 1 0 EBP50, C-terminal BATS PF06968.13 KNZ74171.1 - 4.9e-22 77.9 0.3 1.7e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KNZ74171.1 - 2.6e-17 63.7 0.0 4.3e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Plasmid_RAQPRD PF09686.10 KNZ74171.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) RNase_T PF00929.24 KNZ74172.1 - 3.1e-09 37.6 0.0 5e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF2235 PF09994.9 KNZ74174.1 - 0.00057 19.3 0.3 0.00066 19.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Mad3_BUB1_I PF08311.12 KNZ74175.1 - 0.13 12.3 0.1 17 5.4 0.0 2.8 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 AAA_16 PF13191.6 KNZ74177.1 - 0.14 12.5 0.2 5 7.5 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 KNZ74177.1 - 0.17 12.2 0.1 37 4.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Lyase_1 PF00206.20 KNZ74182.1 - 2.3e-96 322.9 0.0 6.4e-96 321.4 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 KNZ74182.1 - 2.3e-19 69.9 0.3 4.2e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 Argininosuccinate lyase C-terminal Syntaxin PF00804.25 KNZ74183.1 - 5.6e-35 120.8 8.2 8.4e-35 120.3 8.2 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KNZ74183.1 - 4.2e-09 36.3 0.1 1e-08 35.0 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KNZ74183.1 - 1.6e-07 31.6 8.2 7.1e-07 29.5 5.2 2.3 2 0 0 2 2 2 1 Syntaxin-like protein VitD-bind_III PF09164.10 KNZ74183.1 - 0.0053 16.7 0.4 0.015 15.3 0.1 1.8 2 0 0 2 2 2 1 Vitamin D binding protein, domain III PHM7_cyt PF14703.6 KNZ74183.1 - 0.036 14.3 1.4 0.067 13.4 0.2 2.0 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MCPsignal PF00015.21 KNZ74183.1 - 0.038 13.8 1.0 0.038 13.8 1.0 2.5 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CLZ PF16526.5 KNZ74183.1 - 0.043 14.2 3.4 1.8 9.0 0.3 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pox_A_type_inc PF04508.12 KNZ74183.1 - 0.049 13.5 2.0 0.18 11.7 2.0 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2939 PF11159.8 KNZ74183.1 - 0.055 13.9 2.0 0.15 12.5 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) Spectrin PF00435.21 KNZ74183.1 - 0.15 12.6 5.7 3.5 8.2 0.1 3.0 3 1 0 3 3 3 0 Spectrin repeat ALMT PF11744.8 KNZ74183.1 - 0.3 9.9 5.6 0.6 8.9 5.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter V-SNARE PF05008.15 KNZ74183.1 - 0.31 11.4 12.2 0.26 11.7 0.5 3.6 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Syntaxin-6_N PF09177.11 KNZ74183.1 - 0.78 10.3 5.3 9.4 6.9 1.3 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Arc_PepC_II PF06847.11 KNZ74183.1 - 1.8 9.1 3.9 1.9 9.1 0.1 2.6 2 2 1 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II WXG100 PF06013.12 KNZ74183.1 - 2.5 8.4 9.4 3.9 7.8 0.1 3.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF745 PF05335.13 KNZ74183.1 - 3.8 7.2 11.6 0.33 10.7 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF3552 PF12072.8 KNZ74183.1 - 4.3 6.7 13.4 1.3 8.4 0.3 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3552) 4HB_MCP_1 PF12729.7 KNZ74183.1 - 6.9 6.2 15.8 0.29 10.7 0.8 3.9 4 0 0 4 4 4 0 Four helix bundle sensory module for signal transduction zf-AN1 PF01428.16 KNZ74184.1 - 5.7e-10 39.2 8.8 5.7e-10 39.2 8.8 1.8 1 1 0 1 1 1 1 AN1-like Zinc finger Rubredoxin_2 PF18073.1 KNZ74184.1 - 0.0011 18.7 0.7 0.0011 18.7 0.7 1.9 2 0 0 2 2 2 1 Rubredoxin metal binding domain IBR PF01485.21 KNZ74184.1 - 0.037 14.2 10.3 0.045 14.0 9.7 1.5 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain TackOD1 PF18551.1 KNZ74184.1 - 0.046 13.4 8.6 0.052 13.2 8.6 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Aminotran_1_2 PF00155.21 KNZ74185.1 - 2.8e-87 293.3 0.0 3.1e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT PF02985.22 KNZ74186.1 - 1.7e-12 46.4 16.9 0.0039 17.3 0.1 9.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 KNZ74186.1 - 5.1e-08 33.2 19.7 0.00021 21.6 0.0 6.9 7 1 0 7 7 7 2 HEAT repeats Adaptin_N PF01602.20 KNZ74186.1 - 0.00072 18.2 0.0 0.002 16.8 0.0 1.6 2 0 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_N PF03224.14 KNZ74186.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H HEAT_EZ PF13513.6 KNZ74186.1 - 0.062 13.8 16.3 8.1 7.1 0.2 5.8 5 1 1 6 6 6 0 HEAT-like repeat Lig_chan PF00060.26 KNZ74186.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel MARVEL PF01284.23 KNZ74187.1 - 0.00093 19.2 15.2 0.0017 18.4 15.2 1.4 1 0 0 1 1 1 1 Membrane-associating domain 2HCT PF03390.15 KNZ74187.1 - 0.047 12.3 1.7 0.065 11.8 1.7 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family DUF761 PF05553.11 KNZ74188.1 - 0.05 13.2 0.8 0.088 12.4 0.8 1.3 1 0 0 1 1 1 0 Cotton fibre expressed protein FUN14 PF04930.15 KNZ74190.1 - 3.6e-19 69.0 0.5 4.4e-19 68.7 0.5 1.1 1 0 0 1 1 1 1 FUN14 family Methyltr_RsmB-F PF01189.17 KNZ74191.1 - 1.1e-76 257.0 0.0 1.6e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KNZ74191.1 - 2.2e-09 37.7 0.0 9e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 KNZ74191.1 - 0.00047 20.0 0.0 0.00088 19.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 KNZ74191.1 - 0.0046 16.7 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KNZ74191.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KNZ74191.1 - 0.056 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KNZ74191.1 - 0.078 13.7 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF2431 PF10354.9 KNZ74191.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) FtsJ PF01728.19 KNZ74191.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Hexapep PF00132.24 KNZ74192.1 - 9.1e-12 44.2 16.3 0.00028 20.5 5.3 3.8 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KNZ74192.1 - 4.3e-08 33.0 0.0 6.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase W2 PF02020.18 KNZ74192.1 - 5.4e-08 32.9 0.4 2e-07 31.0 0.4 2.0 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.6 KNZ74192.1 - 3.8e-05 23.4 16.2 0.051 13.3 3.8 4.1 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KNZ74192.1 - 6.5e-05 22.0 1.3 0.00013 21.0 1.3 1.5 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 KNZ74192.1 - 0.00016 22.1 0.0 0.00025 21.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KNZ74192.1 - 0.0037 15.5 4.9 0.0069 14.6 4.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) TMEM119 PF15724.5 KNZ74192.1 - 0.18 11.9 6.1 0.45 10.5 6.1 1.6 1 0 0 1 1 1 0 TMEM119 family DUF2201_N PF13203.6 KNZ74192.1 - 1 8.9 8.0 9.9 5.7 4.4 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Presenilin PF01080.17 KNZ74192.1 - 2.4 6.8 3.3 4.7 5.9 3.3 1.4 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 KNZ74192.1 - 4.9 6.5 25.5 1.8 7.9 9.9 2.3 2 0 0 2 2 2 0 SDA1 Abhydrolase_3 PF07859.13 KNZ74193.1 - 1.2e-08 35.1 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KNZ74193.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Aminotran_5 PF00266.19 KNZ74194.1 - 8.6e-10 38.1 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.19 KNZ74195.1 - 2.7e-22 79.5 0.0 5.5e-22 78.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ74195.1 - 1.7e-07 30.8 0.0 1e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ74195.1 - 2.6e-06 27.3 0.0 0.0023 17.6 0.1 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KNZ74195.1 - 6.9e-06 26.5 0.1 2.1e-05 25.0 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ74195.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KNZ74195.1 - 0.0003 20.0 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 KNZ74195.1 - 0.0012 18.2 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KNZ74195.1 - 0.0012 17.6 0.1 0.0018 17.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein XdhC_C PF13478.6 KNZ74195.1 - 0.0034 17.9 0.0 0.058 13.9 0.0 2.5 3 0 0 3 3 3 1 XdhC Rossmann domain FAD_oxidored PF12831.7 KNZ74195.1 - 0.0052 16.2 0.2 0.01 15.2 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 KNZ74195.1 - 0.016 14.3 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase ThiF PF00899.21 KNZ74195.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.24 KNZ74195.1 - 0.022 13.8 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KNZ74195.1 - 0.04 13.2 0.2 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KNZ74195.1 - 0.06 13.2 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 KNZ74195.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 KNZ74195.1 - 0.079 11.8 0.7 0.76 8.5 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KNZ74195.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KNZ74195.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family AT_hook PF02178.19 KNZ74196.1 - 6.7e-06 25.4 50.5 0.026 14.4 3.7 4.5 4 0 0 4 4 4 4 AT hook motif PRKCSH PF07915.13 KNZ74197.1 - 8.1e-16 58.8 0.4 1.5e-15 57.9 0.4 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 KNZ74197.1 - 0.0016 18.1 0.0 0.0077 15.9 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DEAD PF00270.29 KNZ74198.1 - 1.3e-46 158.6 0.0 6.4e-46 156.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pkinase PF00069.25 KNZ74198.1 - 2.5e-42 145.0 0.0 1.4e-41 142.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Helicase_C PF00271.31 KNZ74198.1 - 7.2e-28 97.1 0.0 2.2e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pkinase_Tyr PF07714.17 KNZ74198.1 - 3.4e-24 85.5 0.0 6.2e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ResIII PF04851.15 KNZ74198.1 - 0.0015 18.5 0.0 0.0034 17.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit APH PF01636.23 KNZ74198.1 - 0.027 14.4 0.4 0.027 14.4 0.4 2.8 5 0 0 5 5 5 0 Phosphotransferase enzyme family EF_assoc_2 PF08356.12 KNZ74199.1 - 0.008 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KNZ74199.1 - 0.019 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 EF hand associated RhoGEF PF00621.20 KNZ74200.1 - 4.5e-15 56.3 0.1 7.4e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain Rx_N PF18052.1 KNZ74200.1 - 0.066 13.5 0.7 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Rx N-terminal domain Asn_synthase PF00733.21 KNZ74201.1 - 8.1e-94 315.2 0.0 4.9e-56 190.9 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 KNZ74201.1 - 3e-34 117.6 0.0 5.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KNZ74201.1 - 2e-27 96.0 0.0 3.5e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KNZ74201.1 - 2.5e-05 23.8 0.0 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.13 KNZ74201.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.17 KNZ74201.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Syntaxin PF00804.25 KNZ74202.1 - 1e-21 77.5 12.2 2.3e-21 76.4 12.2 1.5 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 KNZ74202.1 - 1.1e-07 32.1 2.9 1.1e-07 32.1 2.9 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KNZ74202.1 - 8.1e-06 25.8 0.2 4.1e-05 23.5 0.2 2.3 1 0 0 1 1 1 1 SNARE domain Caveolin PF01146.17 KNZ74202.1 - 0.096 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Caveolin DUF2116 PF09889.9 KNZ74202.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Prominin PF05478.11 KNZ74202.1 - 0.18 9.7 2.3 2.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Prominin Tweety PF04906.13 KNZ74202.1 - 0.18 10.4 2.1 0.72 8.4 0.0 2.1 2 1 0 2 2 2 0 Tweety Cnn_1N PF07989.11 KNZ74202.1 - 0.2 11.9 5.2 2.7 8.2 0.3 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DASH_Dam1 PF08653.10 KNZ74202.1 - 0.27 11.0 4.1 5.2 7.0 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 Syntaxin-6_N PF09177.11 KNZ74202.1 - 0.85 10.2 10.1 0.22 12.1 2.7 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4055 PF13264.6 KNZ74202.1 - 2.2 8.4 5.9 0.51 10.5 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) SlyX PF04102.12 KNZ74202.1 - 4.3 8.0 12.5 1.4 9.6 0.6 3.7 3 1 1 4 4 4 0 SlyX CDP-OH_P_transf PF01066.21 KNZ74203.1 - 2.1e-14 54.0 0.3 2.1e-14 54.0 0.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AAA PF00004.29 KNZ74204.1 - 1.4e-35 122.6 0.0 3.6e-35 121.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ74204.1 - 2.1e-11 43.5 0.1 6e-11 42.0 0.0 1.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KNZ74204.1 - 6.7e-06 26.6 0.3 0.0055 17.1 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 KNZ74204.1 - 0.0014 18.9 0.3 0.031 14.5 0.1 3.1 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 KNZ74204.1 - 0.0015 18.5 0.1 0.0093 16.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KNZ74204.1 - 0.0015 18.7 0.0 0.0074 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 KNZ74204.1 - 0.0065 16.2 0.1 0.091 12.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_6 PF12774.7 KNZ74204.1 - 0.0089 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region RuvB_N PF05496.12 KNZ74204.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KNZ74204.1 - 0.012 16.2 0.9 0.041 14.4 0.0 2.4 3 0 0 3 3 1 0 AAA domain DUF4279 PF14106.6 KNZ74204.1 - 0.018 15.3 0.0 3.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) AAA_24 PF13479.6 KNZ74204.1 - 0.025 14.3 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KNZ74204.1 - 0.029 14.2 0.4 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KNZ74204.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KNZ74204.1 - 0.041 14.2 0.5 0.44 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KNZ74204.1 - 0.051 13.8 0.0 0.2 11.9 0.0 2.0 3 0 0 3 3 1 0 AAA domain IPT PF01745.16 KNZ74204.1 - 0.079 12.3 0.1 5 6.4 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Rad17 PF03215.15 KNZ74204.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 KNZ74204.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KNZ74204.1 - 0.13 12.0 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KNZ74204.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ74204.1 - 0.22 11.9 0.0 0.55 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SMC_Nse1 PF07574.13 KNZ74205.1 - 1.5e-31 109.8 1.4 1.2e-30 106.8 1.4 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex CDP-OH_P_transf PF01066.21 KNZ74206.1 - 7.1e-12 45.9 1.1 1.6e-11 44.8 0.6 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase USP7_ICP0_bdg PF12436.8 KNZ74208.1 - 2.7e-83 279.0 0.1 1.4e-82 276.6 0.1 2.2 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KNZ74208.1 - 1.1e-66 224.5 2.1 3.2e-62 209.9 0.1 3.2 2 1 1 3 3 3 3 Ubiquitin-specific protease C-terminal UCH PF00443.29 KNZ74208.1 - 9.6e-51 172.7 0.3 1.6e-50 172.0 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ74208.1 - 1.4e-22 80.8 0.4 3.1e-22 79.6 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KNZ74208.1 - 1.2e-07 31.8 0.0 6e-07 29.6 0.0 2.2 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 KNZ74208.1 - 0.028 14.1 0.1 0.94 9.3 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin family HSDR_N_2 PF13588.6 KNZ74208.1 - 0.061 13.3 0.1 0.65 10.0 0.0 2.6 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) UN_NPL4 PF11543.8 KNZ74208.1 - 0.074 13.5 0.0 0.79 10.3 0.0 2.8 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 KNZ74209.1 - 5.8e-57 192.2 0.1 6.8e-57 191.9 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 StbA PF06406.11 KNZ74209.1 - 0.043 13.0 0.1 0.06 12.6 0.1 1.2 1 0 0 1 1 1 0 StbA protein DUF3216 PF11505.8 KNZ74209.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Citrate_synt PF00285.21 KNZ74210.1 - 1.6e-98 330.1 0.0 1.9e-98 329.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain B56 PF01603.20 KNZ74212.1 - 2.8e-190 632.7 5.3 3.3e-190 632.4 5.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) HSP70 PF00012.20 KNZ74213.1 - 2.9e-231 768.9 6.0 4.3e-156 520.6 0.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KNZ74213.1 - 2.8e-12 46.1 0.0 4.3e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.18 KNZ74213.1 - 0.029 13.7 0.2 0.063 12.5 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase GRP PF07172.11 KNZ74213.1 - 0.049 14.3 4.1 0.13 12.9 4.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family StbA PF06406.11 KNZ74213.1 - 0.077 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 StbA protein PhoD PF09423.10 KNZ74214.1 - 1.1e-70 238.4 2.1 4.2e-58 197.0 0.2 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase PhoD_N PF16655.5 KNZ74214.1 - 1.6e-20 73.4 0.0 4.7e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KNZ74214.1 - 1.9e-05 25.2 0.2 4e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Fungal_trans PF04082.18 KNZ74215.1 - 5.2e-16 58.5 0.3 1.1e-15 57.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sipho_Gp157 PF05565.11 KNZ74216.1 - 0.00012 22.1 0.8 0.00013 22.0 0.8 1.0 1 0 0 1 1 1 1 Siphovirus Gp157 DivIC PF04977.15 KNZ74216.1 - 0.0023 17.7 4.2 0.0032 17.2 4.2 1.2 1 0 0 1 1 1 1 Septum formation initiator Uso1_p115_C PF04871.13 KNZ74216.1 - 0.005 17.2 2.6 0.0062 16.9 2.6 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Rx_N PF18052.1 KNZ74216.1 - 0.0075 16.5 1.8 0.0079 16.4 1.8 1.1 1 0 0 1 1 1 1 Rx N-terminal domain DUF3450 PF11932.8 KNZ74216.1 - 0.01 15.1 1.0 0.011 15.0 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 KNZ74216.1 - 0.014 15.5 2.7 0.016 15.3 2.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 KNZ74216.1 - 0.017 15.3 1.0 0.029 14.6 1.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 KNZ74216.1 - 0.027 15.0 5.6 0.032 14.7 5.6 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor Cnn_1N PF07989.11 KNZ74216.1 - 0.039 14.1 3.9 0.04 14.1 3.0 1.4 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 KNZ74216.1 - 0.04 14.4 1.1 0.046 14.2 1.1 1.1 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF2937 PF11157.8 KNZ74216.1 - 0.058 13.1 1.3 0.066 12.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Matrilin_ccoil PF10393.9 KNZ74216.1 - 0.12 12.2 1.0 0.18 11.7 1.0 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin ox_reductase_C PF08635.10 KNZ74217.1 - 3.2e-72 240.8 0.4 5.1e-72 240.1 0.4 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 KNZ74217.1 - 1.4e-25 90.4 0.1 4.7e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KNZ74217.1 - 0.00061 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain zf-C2HE PF16278.5 KNZ74218.1 - 5.5e-17 62.0 0.4 5.5e-17 62.0 0.4 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KNZ74218.1 - 1.8e-07 31.6 0.4 4.2e-07 30.4 0.2 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KNZ74218.1 - 5.7e-05 23.8 0.0 0.00018 22.2 0.0 1.8 1 0 0 1 1 1 1 HIT domain zf-C2H2_2 PF12756.7 KNZ74218.1 - 0.051 13.9 1.3 0.07 13.5 0.3 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RabGAP-TBC PF00566.18 KNZ74219.1 - 1.6e-38 132.5 5.3 3.1e-36 125.0 1.6 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain 2OG-FeII_Oxy_2 PF13532.6 KNZ74219.1 - 1.8e-34 119.6 0.0 8.7e-33 114.2 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SHR3_chaperone PF08229.11 KNZ74219.1 - 5.1e-28 97.3 0.2 8.3e-28 96.6 0.2 1.3 1 0 0 1 1 1 1 ER membrane protein SH3 PH_RBD PF12068.8 KNZ74219.1 - 8.4e-07 28.6 0.0 8.9e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Rab-binding domain (RBD) Imm63 PF15599.6 KNZ74219.1 - 0.074 13.5 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 63 LETM1 PF07766.13 KNZ74220.1 - 2.8e-86 289.2 3.4 9.8e-84 280.8 0.3 3.4 2 2 1 3 3 3 2 LETM1-like protein EF-hand_7 PF13499.6 KNZ74220.1 - 5.3e-05 23.6 1.1 0.0078 16.6 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair SAP PF02037.27 KNZ74220.1 - 0.00022 20.9 1.0 0.003 17.3 0.0 3.3 3 0 0 3 3 3 1 SAP domain EF-hand_6 PF13405.6 KNZ74220.1 - 0.00098 18.9 0.0 16 5.8 0.0 4.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 KNZ74220.1 - 0.001 18.5 0.0 0.21 11.2 0.0 3.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 KNZ74220.1 - 0.0011 18.7 0.1 0.012 15.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KNZ74220.1 - 0.016 14.7 0.0 0.46 10.1 0.0 2.9 2 0 0 2 2 2 0 EF hand DUF5063 PF16702.5 KNZ74220.1 - 0.021 15.2 1.2 0.053 13.9 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) RsfS PF02410.15 KNZ74221.1 - 1.9e-06 28.2 0.0 2.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation G-patch PF01585.23 KNZ74222.1 - 3.2e-08 33.3 1.1 3.2e-08 33.3 1.1 2.0 2 1 0 2 2 2 1 G-patch domain FAD_binding_2 PF00890.24 KNZ74223.1 - 1.3e-120 403.3 1.1 1.7e-120 402.9 1.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KNZ74223.1 - 9.2e-43 145.3 0.2 1.4e-42 144.7 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 KNZ74223.1 - 8.4e-06 25.1 1.2 0.0074 15.4 2.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KNZ74223.1 - 1.1e-05 24.8 0.2 0.0063 15.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KNZ74223.1 - 2.4e-05 23.7 1.7 0.00039 19.8 0.5 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KNZ74223.1 - 0.0024 17.2 0.2 0.0042 16.4 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNZ74223.1 - 0.012 15.2 0.4 0.022 14.3 0.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KNZ74223.1 - 0.13 10.9 2.0 0.32 9.7 0.7 2.2 3 0 0 3 3 3 0 HI0933-like protein RabGAP-TBC PF00566.18 KNZ74224.1 - 1e-32 113.5 0.0 1.1e-15 57.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain TBCC PF07986.12 KNZ74224.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C CLTH PF10607.9 KNZ74225.1 - 3.5e-22 78.9 0.0 5.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KNZ74225.1 - 1.1e-06 28.5 0.2 2.1e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KNZ74225.1 - 0.0045 16.4 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KNZ74225.1 - 0.028 14.4 0.2 0.045 13.7 0.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 KNZ74225.1 - 0.05 14.0 0.3 0.084 13.2 0.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Nse PF11789.8 KNZ74225.1 - 0.21 11.4 1.0 0.43 10.4 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pellino PF04710.14 KNZ74225.1 - 0.23 10.1 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 Pellino zf-C3HC4_2 PF13923.6 KNZ74225.1 - 0.36 10.7 1.2 0.64 9.9 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GCV_T_C PF08669.11 KNZ74226.1 - 0.034 14.1 0.1 41 4.2 0.0 3.3 3 0 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain PQQ_2 PF13360.6 KNZ74226.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 PQQ-like domain WD40 PF00400.32 KNZ74226.1 - 0.1 13.5 0.0 20 6.2 0.0 3.2 2 0 0 2 2 2 0 WD domain, G-beta repeat PQQ PF01011.21 KNZ74226.1 - 0.14 12.1 0.1 3.6 7.7 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Pirin PF02678.16 KNZ74227.1 - 1.8e-28 98.7 1.0 3.4e-28 97.8 1.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 KNZ74227.1 - 1.9e-17 63.5 0.0 1.1e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 KNZ74227.1 - 0.12 12.1 1.0 0.23 11.2 1.0 1.5 1 0 0 1 1 1 0 Cupin domain AA_permease PF00324.21 KNZ74228.1 - 3e-120 402.0 41.6 3.7e-120 401.8 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ74228.1 - 1.8e-28 99.5 46.3 2.6e-28 99.1 46.3 1.2 1 0 0 1 1 1 1 Amino acid permease ECH_1 PF00378.20 KNZ74229.1 - 5.2e-28 98.0 0.0 6.1e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ74229.1 - 1.4e-20 74.1 0.0 1.5e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase OTU PF02338.19 KNZ74231.1 - 1.3e-21 77.4 0.0 2e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KNZ74231.1 - 0.00025 20.6 0.0 0.34 10.3 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain Metal_resist PF13801.6 KNZ74231.1 - 0.11 12.7 13.4 0.29 11.3 13.4 1.7 1 1 0 1 1 1 0 Heavy-metal resistance Adaptin_N PF01602.20 KNZ74232.1 - 6.8e-123 411.0 1.2 9e-123 410.6 1.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KNZ74232.1 - 1.6e-56 190.8 0.3 2.6e-53 180.4 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ74232.1 - 5.9e-14 52.2 12.4 2.7e-07 30.9 0.4 5.6 4 1 2 6 6 6 4 HEAT repeats HEAT PF02985.22 KNZ74232.1 - 2e-08 33.8 5.5 0.0068 16.6 0.0 6.7 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.23 KNZ74232.1 - 1.9e-07 30.8 2.9 0.31 11.1 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KNZ74232.1 - 0.00022 21.6 1.1 7.5 7.2 0.0 5.8 6 0 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.8 KNZ74232.1 - 0.0057 16.3 0.0 0.061 12.9 0.0 2.5 2 1 0 2 2 2 1 CLASP N terminal DUF4477 PF14780.6 KNZ74233.1 - 6.2e-06 26.0 3.0 0.00075 19.2 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) FlgN PF05130.12 KNZ74233.1 - 0.066 13.7 0.5 6 7.4 0.0 2.3 2 0 0 2 2 2 0 FlgN protein DUF4282 PF14110.6 KNZ74233.1 - 0.45 11.3 4.7 0.51 11.1 3.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Cu_bind_like PF02298.17 KNZ74234.1 - 0.0002 21.3 0.1 0.00044 20.2 0.1 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain KRTAP PF11759.8 KNZ74234.1 - 0.7 10.5 14.4 2.1 9.0 14.3 1.9 1 1 0 1 1 1 0 Keratin-associated matrix Pyr_redox_2 PF07992.14 KNZ74235.1 - 5.6e-12 45.5 0.0 4.6e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ74235.1 - 0.014 15.0 3.7 1.8 8.0 0.1 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ74235.1 - 0.072 13.1 0.3 7.2 6.6 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding UEV PF05743.13 KNZ74236.1 - 2.4e-36 124.3 0.0 3.6e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 KNZ74236.1 - 3.2e-28 97.5 0.4 7e-28 96.4 0.4 1.6 1 0 0 1 1 1 1 Vps23 core domain CortBP2 PF09727.9 KNZ74236.1 - 0.026 14.4 1.0 0.039 13.8 1.0 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 TEA PF01285.18 KNZ74237.1 - 5.4e-16 58.4 0.6 1.2e-15 57.3 0.6 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Pectate_lyase PF03211.13 KNZ74237.1 - 0.2 11.2 0.1 0.33 10.4 0.1 1.3 1 0 0 1 1 1 0 Pectate lyase NOC3p PF07540.11 KNZ74238.1 - 3.6e-33 113.9 0.0 1.7e-32 111.7 0.0 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KNZ74238.1 - 4.2e-19 69.2 0.4 1.1e-17 64.6 0.0 2.9 2 1 1 4 4 4 1 CBF/Mak21 family DUF4337 PF14235.6 KNZ74238.1 - 0.068 13.3 2.0 0.15 12.2 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BSP_II PF05432.11 KNZ74238.1 - 2.3 7.9 12.1 3.5 7.2 1.7 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) ANAPC5 PF12862.7 KNZ74239.1 - 7.7e-10 38.7 0.1 4.2e-09 36.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 KNZ74239.1 - 0.19 11.6 4.4 0.3 11.0 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CLASP_N PF12348.8 KNZ74240.1 - 1.2e-25 90.4 0.5 1.4e-07 31.4 0.0 5.9 5 1 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 KNZ74240.1 - 6.9e-12 44.6 16.1 0.47 10.9 0.0 12.2 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.7 KNZ74240.1 - 5.5e-08 33.0 2.6 0.89 9.6 0.0 7.1 7 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ74240.1 - 2.2e-07 31.1 16.2 1.5 9.3 1.4 9.5 8 2 1 9 9 9 2 HEAT repeats TAN PF11640.8 KNZ74240.1 - 0.00014 22.0 10.1 0.014 15.6 0.1 5.4 5 1 1 6 6 5 2 Telomere-length maintenance and DNA damage repair HEAT_EZ PF13513.6 KNZ74240.1 - 0.00029 21.3 7.5 5 7.7 0.0 6.8 5 1 1 6 6 6 1 HEAT-like repeat MMS19_N PF14500.6 KNZ74240.1 - 0.0059 16.2 6.4 3.6 7.1 0.0 6.2 4 2 2 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 KNZ74240.1 - 0.013 16.1 0.0 50 4.6 0.0 6.0 7 1 0 7 7 7 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.10 KNZ74240.1 - 0.018 14.8 0.0 0.69 9.7 0.0 3.4 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Nipped-B_C PF12830.7 KNZ74240.1 - 0.058 13.3 0.1 23 4.9 0.0 3.6 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus ParcG PF10274.9 KNZ74240.1 - 0.32 11.1 1.7 70 3.5 0.0 4.6 5 0 0 5 5 5 0 Parkin co-regulated protein Tti2 PF10521.9 KNZ74240.1 - 0.37 10.3 2.5 30 4.0 0.0 4.2 4 0 0 4 4 4 0 Tti2 family Acyltransferase PF01553.21 KNZ74241.1 - 1.3e-10 41.0 0.0 2.3e-09 37.0 0.0 2.6 2 1 0 2 2 2 1 Acyltransferase Peptidase_M24 PF00557.24 KNZ74242.1 - 6.4e-38 130.5 0.2 2.6e-29 102.4 0.0 2.1 1 1 1 2 2 2 2 Metallopeptidase family M24 IF-2B PF01008.17 KNZ74244.1 - 6.6e-56 189.6 0.0 8.8e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PGBA_N PF15436.6 KNZ74244.1 - 0.0036 16.9 0.0 0.89 9.1 0.0 2.2 2 0 0 2 2 2 2 Plasminogen-binding protein pgbA N-terminal Cyclin_N PF00134.23 KNZ74245.1 - 3.2e-09 36.6 0.0 8.3e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KNZ74245.1 - 7.5e-06 26.0 0.9 0.078 13.1 0.0 2.6 3 0 0 3 3 3 2 Cyclin, C-terminal domain TFIIB PF00382.19 KNZ74245.1 - 0.00025 21.0 0.2 0.0034 17.4 0.0 2.6 3 0 0 3 3 3 1 Transcription factor TFIIB repeat Ribosomal_S21 PF01165.20 KNZ74248.1 - 1.4e-15 56.8 2.7 2.3e-15 56.0 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 ADIP PF11559.8 KNZ74248.1 - 0.038 14.1 3.9 0.046 13.8 3.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RWD PF05773.22 KNZ74249.1 - 2.8e-17 63.1 0.0 5.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KNZ74249.1 - 7.5e-06 26.3 5.9 1.1e-05 25.8 5.0 1.7 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Abhydrolase_6 PF12697.7 KNZ74250.1 - 5e-08 33.8 2.3 8.1e-08 33.1 2.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ74250.1 - 3.9e-07 30.0 0.2 2.6e-06 27.3 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ74250.1 - 1.2e-06 28.0 0.0 1.1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Muted PF14942.6 KNZ74251.1 - 0.0012 19.2 0.6 1.4 9.2 0.0 2.3 2 0 0 2 2 2 2 Organelle biogenesis, Muted-like protein CSTF2_hinge PF14327.6 KNZ74251.1 - 0.025 15.0 0.7 0.068 13.6 0.7 1.7 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF2357 PF09823.9 KNZ74251.1 - 0.15 11.3 0.2 0.26 10.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DUF748 PF05359.11 KNZ74252.1 - 0.0055 16.9 0.2 0.019 15.1 0.0 1.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF748) adh_short PF00106.25 KNZ74253.1 - 2.1e-42 144.8 6.0 5e-41 140.3 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ74253.1 - 6.2e-28 97.9 1.2 8.3e-28 97.5 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ74253.1 - 9.4e-10 38.7 2.2 6.9e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 KR domain Queuosine_synth PF02547.15 KNZ74253.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein SET PF00856.28 KNZ74254.1 - 8.8e-05 23.0 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 SET domain SUI1 PF01253.22 KNZ74255.1 - 1e-23 83.7 1.0 1.9e-23 82.8 1.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3584 PF12128.8 KNZ74255.1 - 0.0026 15.4 0.5 0.0029 15.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) TnpV PF14198.6 KNZ74255.1 - 0.1 12.6 3.2 0.1 12.6 2.0 1.6 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Bacillus_HBL PF05791.11 KNZ74255.1 - 0.11 12.3 2.7 0.22 11.3 2.7 1.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PAP2 PF01569.21 KNZ74257.1 - 7.9e-15 54.8 12.7 2.2e-14 53.4 12.7 1.6 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KNZ74257.1 - 0.0024 18.0 0.7 0.0024 18.0 0.7 2.4 1 1 0 2 2 2 1 Divergent PAP2 family Shisa PF13908.6 KNZ74257.1 - 0.0096 16.2 0.8 0.013 15.7 0.8 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM173 PF15009.6 KNZ74257.1 - 0.19 10.8 1.6 0.22 10.7 1.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 173 Phage_holin_3_6 PF07332.11 KNZ74257.1 - 0.9 9.6 7.1 6.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4191 PF13829.6 KNZ74257.1 - 8.4 5.7 10.2 0.72 9.2 5.0 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4191) DnaJ PF00226.31 KNZ74258.1 - 4.5e-20 71.5 1.4 1.8e-19 69.6 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain TetR_C_8 PF14278.6 KNZ74258.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region RAI16-like PF10257.9 KNZ74259.1 - 3.8e-72 243.1 0.1 5.7e-72 242.6 0.1 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CPSF_A PF03178.15 KNZ74260.1 - 2.3e-77 260.5 0.0 4e-77 259.7 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 KNZ74260.1 - 7.2e-22 77.7 0.0 1.8e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DEAD PF00270.29 KNZ74262.1 - 4e-16 59.3 0.0 7.2e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 KNZ74262.1 - 7.7e-07 29.8 0.1 3.2e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 RecQ zinc-binding Helicase_C PF00271.31 KNZ74262.1 - 9.8e-07 29.1 0.0 1.1e-05 25.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ74262.1 - 0.0018 18.3 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FYDLN_acid PF09538.10 KNZ74262.1 - 2.2 9.0 8.2 5.1 7.8 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) ATP_bind_1 PF03029.17 KNZ74263.1 - 3.1e-77 259.6 0.0 3.7e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KNZ74263.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 KNZ74263.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB C1ORF64 PF15547.6 KNZ74263.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein MMR_HSR1 PF01926.23 KNZ74263.1 - 0.19 11.8 0.1 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase APH PF01636.23 KNZ74264.1 - 4e-10 40.0 0.0 9.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KNZ74264.1 - 1.9e-05 23.7 0.0 0.0053 15.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) GMC_oxred_N PF00732.19 KNZ74265.1 - 2.1e-65 221.0 0.0 2.7e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ74265.1 - 2.2e-34 119.0 0.0 3.6e-34 118.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ74265.1 - 0.00053 20.2 0.0 0.0031 17.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KNZ74265.1 - 0.0025 17.0 0.1 0.064 12.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KNZ74265.1 - 0.0054 16.0 0.0 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KNZ74265.1 - 0.0082 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KNZ74265.1 - 0.033 13.4 0.0 0.054 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BMF PF15185.6 KNZ74265.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis FF PF01846.19 KNZ74265.1 - 0.15 12.2 0.2 0.43 10.8 0.3 1.7 2 0 0 2 2 2 0 FF domain GMC_oxred_N PF00732.19 KNZ74266.1 - 2.3e-65 220.9 0.0 2.9e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ74266.1 - 9.3e-38 130.0 0.0 1.5e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ74266.1 - 0.00011 22.4 0.0 0.00036 20.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ74266.1 - 0.00032 19.9 0.1 0.00047 19.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KNZ74266.1 - 0.0018 17.6 0.0 0.0078 15.5 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KNZ74266.1 - 0.0037 16.4 0.0 0.011 14.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KNZ74266.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KNZ74266.1 - 0.032 13.8 0.1 0.077 12.6 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ74266.1 - 0.045 13.0 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KNZ74266.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TPR_12 PF13424.6 KNZ74267.1 - 2.7e-12 46.8 13.4 1.2e-05 25.5 0.7 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74267.1 - 1.8e-08 33.8 10.4 0.0045 17.0 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ74267.1 - 4.8e-05 23.8 10.3 0.48 11.4 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ74267.1 - 0.00031 20.7 0.7 5.2 7.5 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ74267.1 - 0.00036 20.1 1.5 0.69 9.6 1.2 3.6 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 KNZ74267.1 - 0.00055 19.6 7.7 0.09 12.6 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ74267.1 - 0.006 16.4 7.1 0.84 9.6 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ74267.1 - 0.014 15.9 7.4 3.8 8.1 0.1 5.0 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ74267.1 - 0.015 15.3 8.6 13 6.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.9 KNZ74267.1 - 0.026 14.2 0.1 0.071 12.8 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KNZ74267.1 - 0.032 14.9 4.0 0.35 11.6 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74267.1 - 0.036 14.7 6.3 0.1 13.3 0.2 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 KNZ74267.1 - 0.081 12.5 2.3 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_9 PF13371.6 KNZ74267.1 - 1.1 9.5 6.1 4.2 7.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyoxalase_2 PF12681.7 KNZ74268.1 - 0.17 11.8 2.9 0.18 11.7 1.7 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain YnfE PF17452.2 KNZ74268.1 - 0.18 12.1 4.6 0.24 11.7 3.2 2.1 1 1 0 1 1 1 0 Uncharacterized YnfE-like Arnt_C PF18583.1 KNZ74268.1 - 0.95 9.1 5.8 0.53 9.9 2.4 2.1 1 1 0 2 2 2 0 Aminoarabinose transferase C-terminal domain WD40 PF00400.32 KNZ74269.1 - 1.1e-08 35.6 8.2 0.1 13.5 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat SRA1 PF07304.11 KNZ74269.1 - 4.9e-06 26.4 0.0 4.9e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 KNZ74269.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 Prp18 PF02840.15 KNZ74269.1 - 0.098 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain DUF3106 PF11304.8 KNZ74271.1 - 0.016 15.7 0.8 0.022 15.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) ELFV_dehydrog PF00208.21 KNZ74273.1 - 2.1e-72 243.8 0.3 2.6e-72 243.5 0.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KNZ74273.1 - 6.7e-44 148.9 0.0 2e-38 131.2 0.0 2.5 2 0 0 2 2 2 2 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Transp_cyt_pur PF02133.15 KNZ74275.1 - 4.1e-27 95.0 33.6 3e-26 92.2 33.6 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Acetyltransf_3 PF13302.7 KNZ74276.1 - 8.3e-12 46.0 0.0 1.1e-11 45.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ74276.1 - 0.0089 16.3 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family zf-RING_2 PF13639.6 KNZ74277.1 - 6e-07 29.7 7.8 1.6e-06 28.4 7.8 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 KNZ74277.1 - 1.2e-05 25.4 3.9 2.6e-05 24.3 3.9 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 KNZ74277.1 - 0.0018 18.3 1.5 0.0043 17.1 1.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KNZ74277.1 - 0.0039 17.5 6.2 0.012 15.9 6.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING-like PF08746.11 KNZ74277.1 - 0.064 13.6 6.5 0.18 12.1 6.5 1.8 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 KNZ74277.1 - 0.099 12.3 4.6 0.22 11.2 4.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 KNZ74277.1 - 0.11 12.7 5.8 0.38 10.9 5.8 2.1 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 KNZ74277.1 - 0.26 11.2 7.5 0.69 9.8 7.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 KNZ74277.1 - 0.29 11.3 2.9 0.88 9.7 2.9 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 KNZ74277.1 - 0.3 11.0 3.5 0.19 11.6 1.5 1.7 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 KNZ74277.1 - 0.4 10.6 8.9 0.5 10.3 7.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_90 PF05686.12 KNZ74278.1 - 4.9e-14 52.1 0.6 6.2e-13 48.4 0.2 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Flavin_Reduct PF01613.18 KNZ74279.1 - 8.8e-20 71.3 0.0 1.2e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain LAT PF15234.6 KNZ74279.1 - 0.027 14.2 0.0 0.061 13.1 0.0 1.5 2 0 0 2 2 2 0 Linker for activation of T-cells Peptidase_M43 PF05572.13 KNZ74280.1 - 6.9e-19 68.3 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KNZ74280.1 - 4e-07 30.6 0.0 6.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KNZ74280.1 - 0.00044 20.5 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KNZ74280.1 - 0.014 15.0 0.3 0.019 14.6 0.3 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4671 PF15710.5 KNZ74280.1 - 0.073 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4671) Peptidase_M10 PF00413.24 KNZ74280.1 - 0.078 12.8 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_2 PF13574.6 KNZ74280.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Methyltransf_2 PF00891.18 KNZ74282.1 - 1.1e-24 87.0 0.0 7.4e-24 84.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KNZ74282.1 - 0.002 18.8 0.0 0.014 16.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ74282.1 - 0.0035 18.0 0.0 0.0082 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 KNZ74282.1 - 0.039 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_PK PF05891.12 KNZ74282.1 - 0.06 12.9 0.0 0.17 11.3 0.0 1.8 2 1 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 KNZ74282.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3783 PF12646.7 KNZ74282.1 - 0.078 13.0 0.0 1.1 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) WD40 PF00400.32 KNZ74283.1 - 6.6e-17 61.6 17.5 0.0035 18.2 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ74283.1 - 1.1e-07 32.1 1.1 0.0051 17.1 0.1 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ74283.1 - 1.1e-05 24.5 0.0 0.52 9.2 0.0 3.8 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CytB6-F_Fe-S PF08802.10 KNZ74288.1 - 0.01 15.8 1.3 0.17 11.9 0.1 2.4 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit PIF1 PF05970.14 KNZ74291.1 - 8e-08 31.8 0.1 2e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 PIF1-like helicase APH PF01636.23 KNZ74292.1 - 8.1e-07 29.2 0.2 1.8e-06 28.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ74292.1 - 0.00041 19.8 0.0 0.00053 19.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ74292.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase MFS_1 PF07690.16 KNZ74293.1 - 1.4e-35 122.9 28.7 1.4e-35 122.9 28.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ74293.1 - 2.8e-34 118.8 23.8 5.6e-34 117.8 23.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MtrF PF09472.10 KNZ74293.1 - 1.7 8.1 4.5 4.5 6.7 1.7 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) APH PF01636.23 KNZ74295.1 - 0.00011 22.2 0.0 0.00017 21.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ74295.1 - 0.0046 16.6 0.1 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Laminin_II PF06009.12 KNZ74297.1 - 0.096 12.7 2.5 0.15 12.0 0.4 2.1 2 0 0 2 2 2 0 Laminin Domain II CRISPR_assoc PF08798.11 KNZ74298.1 - 0.044 13.9 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR associated protein zf-CSL PF05207.13 KNZ74298.1 - 0.059 13.1 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger Phage_portal PF04860.12 KNZ74299.1 - 0.041 13.1 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage portal protein Suf PF05843.14 KNZ74299.1 - 0.73 9.8 4.5 1.2 9.0 4.5 1.5 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 KNZ74300.1 - 1.1e-10 41.3 0.1 3.2e-09 36.5 0.0 2.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74300.1 - 0.0011 18.3 0.0 0.049 12.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase PIF1 PF05970.14 KNZ74301.1 - 1.1e-12 47.8 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase MFS_1 PF07690.16 KNZ74302.1 - 1.4e-34 119.6 34.2 1.4e-34 119.6 34.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Glycophorin_A PF01102.18 KNZ74302.1 - 0.089 13.0 0.3 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 Glycophorin A Amidohydro_1 PF01979.20 KNZ74303.1 - 1.3e-16 60.9 0.0 1.1e-15 57.8 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 KNZ74303.1 - 2.3e-06 27.3 0.2 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Cutinase PF01083.22 KNZ74304.1 - 7.1e-43 146.6 0.1 8.3e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KNZ74304.1 - 0.00037 20.1 0.1 0.00048 19.8 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.25 KNZ74304.1 - 0.00048 20.0 0.0 0.00072 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 KNZ74304.1 - 0.00055 19.6 0.2 0.00093 18.8 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KNZ74304.1 - 0.00091 18.9 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.11 KNZ74304.1 - 0.0019 18.1 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_8 PF06259.12 KNZ74304.1 - 0.035 13.8 0.8 0.093 12.4 0.8 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 KNZ74304.1 - 0.045 14.4 1.0 0.05 14.2 1.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIP PF03583.14 KNZ74304.1 - 0.12 11.7 0.2 0.18 11.1 0.2 1.2 1 0 0 1 1 1 0 Secretory lipase F-box-like PF12937.7 KNZ74307.1 - 0.00025 20.9 1.2 0.019 14.9 0.1 2.9 3 0 0 3 3 3 2 F-box-like CcmD PF04995.14 KNZ74309.1 - 0.025 14.7 0.2 0.047 13.8 0.2 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) EphA2_TM PF14575.6 KNZ74309.1 - 0.11 13.4 0.1 3.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 KNZ74309.1 - 0.11 12.7 0.8 0.27 11.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Ndc1_Nup PF09531.10 KNZ74309.1 - 1 7.9 11.2 1.5 7.4 11.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 KNZ74309.1 - 5.8 6.7 8.6 9.7 6.0 8.6 1.3 1 0 0 1 1 1 0 SPX domain Thioesterase PF00975.20 KNZ74310.1 - 1.9e-09 38.0 0.0 2.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 KNZ74310.1 - 6.3e-05 23.7 0.0 6.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DPBB_1 PF03330.18 KNZ74310.1 - 0.00034 20.8 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KNZ74310.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Barwin family DUF2974 PF11187.8 KNZ74310.1 - 0.21 11.1 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Isy1 PF06246.12 KNZ74311.1 - 2.1e-59 201.2 2.3 2.5e-59 200.9 2.3 1.0 1 0 0 1 1 1 1 Isy1-like splicing family sCache_like PF16736.5 KNZ74311.1 - 0.094 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Single Cache-like UbiA PF01040.18 KNZ74313.1 - 1.1e-14 54.4 24.6 7.3e-12 45.1 20.0 2.7 1 1 1 2 2 2 2 UbiA prenyltransferase family DUF4660 PF15559.6 KNZ74314.1 - 0.065 13.5 0.5 0.18 12.1 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4660) PROCN PF08083.11 KNZ74314.1 - 0.11 11.2 0.6 0.14 10.8 0.6 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain DPBB_1 PF03330.18 KNZ74315.1 - 0.00011 22.4 0.0 0.00019 21.6 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 KNZ74315.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 Barwin family polyprenyl_synt PF00348.17 KNZ74318.1 - 1.2e-53 181.8 0.0 1.5e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Gcn1_N PF12074.8 KNZ74319.1 - 4.6e-81 272.9 0.5 1.1e-79 268.4 0.0 3.3 2 1 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 KNZ74319.1 - 1.8e-33 111.7 7.8 0.17 12.2 0.0 18.8 19 0 0 19 19 18 7 HEAT repeat HEAT_2 PF13646.6 KNZ74319.1 - 8e-27 93.5 21.1 4.3e-05 23.8 0.0 13.7 11 2 4 15 15 15 7 HEAT repeats HEAT_EZ PF13513.6 KNZ74319.1 - 2.2e-26 91.9 22.9 0.0051 17.3 0.1 16.0 16 1 2 18 18 15 5 HEAT-like repeat CLASP_N PF12348.8 KNZ74319.1 - 4e-13 49.5 0.0 0.0018 17.9 0.0 6.6 4 2 1 7 7 7 2 CLASP N terminal Cnd1 PF12717.7 KNZ74319.1 - 3.4e-11 43.5 0.1 0.74 9.8 0.0 9.0 6 2 3 9 9 8 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KNZ74319.1 - 5e-06 25.3 2.6 3.6 6.0 0.0 6.5 6 1 0 6 6 6 2 Adaptin N terminal region UME PF08064.13 KNZ74319.1 - 6.2e-06 26.1 2.1 2.5 8.0 0.0 8.0 9 0 0 9 9 9 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 KNZ74319.1 - 1.1e-05 26.0 0.0 17 6.1 0.0 6.7 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 KNZ74319.1 - 3e-05 23.3 3.9 0.21 10.7 0.0 6.6 7 1 0 7 7 7 1 Interferon-related developmental regulator (IFRD) RTP1_C1 PF10363.9 KNZ74319.1 - 0.00023 21.3 0.2 5.8 7.1 0.0 6.7 8 1 1 9 9 8 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 KNZ74319.1 - 0.0028 17.4 16.8 0.11 12.2 0.1 7.6 7 1 1 8 8 8 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 KNZ74319.1 - 0.0031 17.4 1.0 11 6.0 0.0 6.2 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) MMS19_N PF14500.6 KNZ74319.1 - 0.014 15.0 2.2 27 4.2 0.0 5.6 7 0 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II U3snoRNP10 PF12397.8 KNZ74319.1 - 0.21 12.0 11.9 5.9 7.3 0.0 6.8 7 0 0 7 7 6 0 U3 small nucleolar RNA-associated protein 10 TFCD_C PF12612.8 KNZ74319.1 - 1.1 9.1 5.7 88 2.9 0.0 5.6 7 0 0 7 7 7 0 Tubulin folding cofactor D C terminal HEAT_PBS PF03130.16 KNZ74319.1 - 4.7 8.2 13.4 38 5.4 0.1 7.8 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat CTK3 PF12243.8 KNZ74320.1 - 4.3e-38 130.1 0.0 6.1e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KNZ74320.1 - 5.4e-26 90.5 2.3 1e-25 89.7 2.3 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CoA_transf_3 PF02515.17 KNZ74322.1 - 5.2e-104 348.3 0.0 5.9e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lactonase PF10282.9 KNZ74323.1 - 2.9e-51 174.8 0.0 3.3e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PrpF PF04303.13 KNZ74324.1 - 1.1e-75 255.0 0.6 3.1e-75 253.5 0.6 1.6 1 1 0 1 1 1 1 PrpF protein Integrase_H2C2 PF17921.1 KNZ74325.1 - 2.4e-07 30.7 0.2 2.4e-07 30.7 0.2 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain RVT_1 PF00078.27 KNZ74325.1 - 2.4e-06 27.2 0.0 3.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ski_Sno PF02437.17 KNZ74325.1 - 0.077 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 SKI/SNO/DAC family RVT_1 PF00078.27 KNZ74326.1 - 0.05 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_hydro_7 PF00840.20 KNZ74328.1 - 3e-212 705.1 17.4 3.9e-212 704.7 17.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KNZ74328.1 - 1.4e-12 47.3 14.4 1.4e-12 47.3 14.4 4.3 5 0 0 5 5 5 1 Fungal cellulose binding domain Glyco_hydro_7 PF00840.20 KNZ74329.1 - 6.3e-212 704.0 14.1 7.1e-212 703.8 14.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF1707 PF08044.11 KNZ74332.1 - 0.074 13.1 1.7 0.15 12.2 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Tli4_N PF18443.1 KNZ74332.1 - 0.12 12.7 1.7 0.16 12.4 1.3 1.4 1 1 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Hid1 PF12722.7 KNZ74332.1 - 0.7 8.0 5.7 0.8 7.8 5.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCRS_N PF13325.6 KNZ74332.1 - 1.4 8.9 5.8 2.5 8.1 5.8 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein PGA2 PF07543.12 KNZ74332.1 - 1.7 8.6 13.3 5.5 7.0 7.0 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 S-antigen PF05756.11 KNZ74332.1 - 4.9 7.6 7.4 5.8 7.4 1.2 2.4 2 0 0 2 2 2 0 S-antigen protein Abhydrolase_3 PF07859.13 KNZ74334.1 - 7.8e-27 94.5 0.0 1.1e-26 94.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KNZ74334.1 - 2.7e-11 42.9 0.2 1.5e-10 40.5 0.0 2.1 3 0 0 3 3 3 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 KNZ74334.1 - 0.1 13.2 0.7 0.17 12.5 0.7 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KNZ74334.1 - 0.14 11.7 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box PF00646.33 KNZ74336.1 - 6.2e-05 22.8 0.2 0.00015 21.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ74336.1 - 0.0021 17.9 0.1 0.0086 15.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like DMA PF03474.14 KNZ74336.1 - 0.068 12.8 0.2 3.3 7.4 0.0 2.8 2 0 0 2 2 2 0 DMRTA motif FTO_CTD PF12934.7 KNZ74336.1 - 0.079 12.7 2.0 0.18 11.6 2.0 1.5 1 0 0 1 1 1 0 FTO C-terminal domain DUF1798 PF08807.10 KNZ74336.1 - 0.75 10.0 3.4 0.69 10.1 1.5 1.9 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) Glyoxal_oxid_N PF07250.11 KNZ74337.1 - 1.8e-26 92.8 0.1 1.6e-24 86.4 0.0 3.7 4 1 0 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ74337.1 - 1.7e-17 63.5 0.0 4e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KNZ74337.1 - 0.00029 21.0 0.3 8.6 6.8 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Glyoxal_oxid_N PF07250.11 KNZ74338.1 - 6.6e-28 97.5 0.0 6.7e-27 94.2 0.0 2.4 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ74338.1 - 1e-21 77.0 0.8 7.1e-21 74.3 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KNZ74338.1 - 0.0042 17.3 0.2 8 6.9 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 KNZ74338.1 - 0.0057 16.6 0.0 17 5.6 0.1 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 KNZ74338.1 - 0.02 14.9 0.8 2 8.5 0.0 4.0 5 0 0 5 5 5 0 Galactose oxidase, central domain COesterase PF00135.28 KNZ74339.1 - 7.3e-54 183.5 0.1 1.7e-46 159.2 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ74339.1 - 0.00028 20.8 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4666 PF15697.5 KNZ74341.1 - 0.018 15.7 6.9 0.75 10.5 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4666) Cpn60_TCP1 PF00118.24 KNZ74343.1 - 1.1e-143 479.5 1.9 1.2e-143 479.3 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 KNZ74343.1 - 0.074 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Pkinase_fungal PF17667.1 KNZ74344.1 - 1.4e-06 27.4 1.0 3.7e-06 26.0 1.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Tab2_like PF06485.11 KNZ74344.1 - 0.032 13.7 0.7 0.042 13.4 0.7 1.2 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Pkinase PF00069.25 KNZ74345.1 - 9.4e-10 38.3 0.0 1.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74345.1 - 0.00088 18.6 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3461 PF11944.8 KNZ74345.1 - 0.12 12.5 0.0 8.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) FAD_binding_3 PF01494.19 KNZ74346.1 - 1.2e-21 77.3 0.1 3.5e-21 75.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KNZ74346.1 - 1.1e-09 37.8 0.8 3.2e-09 36.3 0.8 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ74346.1 - 7.7e-07 29.2 1.4 2.2e-06 27.8 1.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ74346.1 - 1.3e-06 28.3 6.1 4.2e-06 26.6 3.8 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ74346.1 - 1.6e-06 27.6 0.7 0.00024 20.4 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ74346.1 - 0.0005 19.4 0.2 0.00097 18.4 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Rossmann-like PF10727.9 KNZ74346.1 - 0.00056 19.8 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain FAD_binding_2 PF00890.24 KNZ74346.1 - 0.0016 17.6 3.6 0.0045 16.1 3.1 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KNZ74346.1 - 0.0023 16.8 1.0 0.23 10.3 1.0 2.3 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 KNZ74346.1 - 0.0028 18.2 0.2 0.011 16.3 0.2 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KNZ74346.1 - 0.004 16.5 0.2 0.0081 15.5 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.16 KNZ74346.1 - 0.013 15.1 1.0 0.024 14.3 1.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KNZ74346.1 - 0.064 12.3 1.4 0.087 11.9 0.8 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KNZ74346.1 - 0.073 12.4 1.6 0.11 11.8 1.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KNZ74346.1 - 0.11 11.7 1.1 0.55 9.4 1.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KNZ74346.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 KNZ74346.1 - 0.12 12.2 0.4 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 KNZ74346.1 - 0.18 10.5 1.1 0.31 9.7 1.1 1.3 1 0 0 1 1 1 0 HI0933-like protein F-box PF00646.33 KNZ74348.1 - 0.0012 18.7 0.4 0.0041 17.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KNZ74348.1 - 0.0079 16.1 0.9 0.042 13.8 0.5 2.2 2 0 0 2 2 2 1 F-box-like PHINT_rpt PF14882.6 KNZ74349.1 - 0.038 14.3 0.1 1 9.7 0.1 2.7 2 0 0 2 2 2 0 Phage-integrase repeat unit Ribosomal_S17 PF00366.20 KNZ74349.1 - 0.15 12.2 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S17 CBM_1 PF00734.18 KNZ74350.1 - 5.7e-08 32.6 11.4 2.3e-07 30.7 11.4 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 KNZ74350.1 - 6.1e-05 23.5 5.5 0.00013 22.5 5.5 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Helitron_like_N PF14214.6 KNZ74353.1 - 8e-16 58.8 0.1 1.1e-15 58.4 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_6 PF12774.7 KNZ74354.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region MitMem_reg PF13012.6 KNZ74354.1 - 0.21 12.0 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ74355.1 - 3.5e-31 108.7 0.1 3.9e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74355.1 - 0.00059 19.6 0.0 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ74355.1 - 0.00089 19.7 0.0 0.00099 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ74355.1 - 0.0027 17.7 0.0 0.0027 17.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2791 PF10923.8 KNZ74355.1 - 0.0045 15.9 0.0 0.0054 15.6 0.0 1.1 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.18 KNZ74355.1 - 0.0098 15.7 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 KNZ74355.1 - 0.061 13.6 0.1 0.09 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KNZ74355.1 - 0.076 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KNZ74355.1 - 0.091 12.3 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ74355.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.25 KNZ74355.1 - 0.16 11.6 0.1 0.2 11.3 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 KNZ74355.1 - 0.17 12.3 0.4 1.5 9.2 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 KNZ74356.1 - 2.6e-06 25.7 0.0 2.7e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ74356.1 - 0.075 12.9 0.2 0.19 11.6 0.1 1.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Fez1 PF06818.15 KNZ74357.1 - 0.00037 21.0 7.4 0.00037 21.0 7.4 1.6 2 0 0 2 2 2 1 Fez1 DUF4200 PF13863.6 KNZ74357.1 - 0.0014 19.0 10.3 0.0037 17.6 10.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) UPF0242 PF06785.11 KNZ74357.1 - 0.0018 18.4 6.7 0.0035 17.5 6.7 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KNZ74357.1 - 0.011 14.7 10.2 0.015 14.2 9.0 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 KNZ74357.1 - 0.027 13.8 6.8 0.049 13.0 6.8 1.5 1 0 0 1 1 1 0 FAM76 protein Atg14 PF10186.9 KNZ74357.1 - 0.073 12.2 6.0 0.12 11.5 6.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 KNZ74357.1 - 0.23 11.6 17.4 0.48 10.6 17.4 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Sipho_Gp157 PF05565.11 KNZ74357.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.7 2 1 0 2 2 2 0 Siphovirus Gp157 Spore_III_AB PF09548.10 KNZ74357.1 - 2.6 8.1 9.6 14 5.7 5.6 3.4 1 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Sec20 PF03908.13 KNZ74357.1 - 3.5 7.6 5.1 1.3 9.0 0.3 2.7 4 0 0 4 4 4 0 Sec20 DUF641 PF04859.12 KNZ74357.1 - 3.7 7.9 8.2 4 7.8 5.8 2.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.15 KNZ74357.1 - 5.8 6.4 11.1 2.7 7.5 8.5 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit BRE1 PF08647.11 KNZ74357.1 - 7.1 6.8 15.0 1.6 8.8 11.4 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase KR PF08659.10 KNZ74358.1 - 1.9e-05 24.6 0.1 6.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 KNZ74358.1 - 0.00047 19.7 0.2 0.0021 17.6 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase GAS PF13851.6 KNZ74358.1 - 0.039 13.3 30.6 0.21 10.9 5.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 KNZ74358.1 - 0.32 11.4 27.5 0.51 10.8 7.5 2.5 1 1 1 2 2 2 0 Fez1 LMBR1 PF04791.16 KNZ74358.1 - 0.56 9.0 7.7 1.2 7.9 7.7 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein HOOK PF05622.12 KNZ74358.1 - 0.79 7.8 30.1 2.2 6.3 28.4 1.8 1 1 1 2 2 2 0 HOOK protein PRKG1_interact PF15898.5 KNZ74358.1 - 3 8.8 28.0 8 7.4 10.0 3.0 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain EspB_PE PF18625.1 KNZ74358.1 - 3.5 8.1 10.3 9.5 6.8 0.1 3.4 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain APG6_N PF17675.1 KNZ74358.1 - 3.6 8.1 30.2 2.1 8.9 26.4 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 KNZ74358.1 - 8.8 5.1 29.9 0.62 8.9 17.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Peptidase_M22 PF00814.25 KNZ74359.1 - 0.086 12.5 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Glycoprotease family Lpp-LpqN PF10738.9 KNZ74359.1 - 0.19 11.2 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Probable lipoprotein LpqN DUF3686 PF12458.8 KNZ74359.1 - 0.26 9.7 1.0 3.1 6.2 0.1 2.1 2 0 0 2 2 2 0 ATPase involved in DNA repair Questin_oxidase PF14027.6 KNZ74360.1 - 0.0095 15.5 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Questin oxidase-like SH3BP5 PF05276.14 KNZ74360.1 - 0.12 12.1 0.4 0.34 10.7 0.1 1.9 2 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) PKcGMP_CC PF16808.5 KNZ74360.1 - 0.56 10.1 2.7 1.6 8.7 2.2 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CEP63 PF17045.5 KNZ74360.1 - 0.77 9.6 4.0 0.2 11.6 0.5 1.7 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa 3-alpha PF03475.14 KNZ74361.1 - 0.12 12.3 2.2 0.47 10.4 0.1 2.9 3 0 0 3 3 3 0 3-alpha domain Mito_carr PF00153.27 KNZ74362.1 - 1.6e-55 185.0 1.0 2e-18 66.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Alpha_L_fucos PF01120.17 KNZ74365.1 - 1.1e-77 261.9 3.8 1.4e-77 261.5 3.8 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase ARD PF03079.14 KNZ74366.1 - 2.1e-44 151.5 0.0 2.5e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 KNZ74366.1 - 8.3e-10 38.2 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KNZ74366.1 - 6.2e-06 26.2 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 KNZ74366.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KNZ74366.1 - 0.038 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF1846 PF08903.11 KNZ74366.1 - 0.047 12.3 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Cupin_8 PF13621.6 KNZ74366.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.7 KNZ74366.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Cupin Pkinase PF00069.25 KNZ74367.1 - 5.7e-09 35.7 0.0 7.4e-08 32.1 0.0 2.1 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74367.1 - 0.0035 16.6 0.0 0.084 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase gag_pre-integrs PF13976.6 KNZ74368.1 - 7.5e-08 32.1 0.1 7.5e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KNZ74368.1 - 0.00052 19.7 0.3 0.00086 19.0 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 KNZ74369.1 - 7.5e-08 32.1 0.1 7.5e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KNZ74369.1 - 0.00052 19.7 0.3 0.00086 19.0 0.3 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pkinase PF00069.25 KNZ74370.1 - 3e-09 36.6 0.0 7e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74370.1 - 0.01 15.2 0.0 0.036 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase EphA2_TM PF14575.6 KNZ74371.1 - 0.12 13.3 0.1 0.33 11.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF5316 PF17247.2 KNZ74371.1 - 0.25 11.4 0.9 0.59 10.2 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5316) Kdo PF06293.14 KNZ74372.1 - 7.6e-06 25.4 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ74372.1 - 0.0004 20.4 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ74372.1 - 0.0036 16.7 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.11 KNZ74372.1 - 0.021 14.5 0.1 0.034 13.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KNZ74372.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KNZ74372.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KNZ74372.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RVP_2 PF08284.11 KNZ74373.1 - 0.047 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease FAD_binding_3 PF01494.19 KNZ74375.1 - 1.7e-24 86.7 0.0 1.6e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 KNZ74375.1 - 0.0054 15.8 0.0 1.6 7.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 KNZ74375.1 - 0.013 15.7 0.3 0.03 14.6 0.3 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Phage_holin_5_2 PF16079.5 KNZ74376.1 - 4.2 7.8 12.0 2.6 8.4 2.1 4.1 3 1 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V DUF2919 PF11143.8 KNZ74376.1 - 7.3 6.9 12.6 0.073 13.4 1.5 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF2919) TRI5 PF06330.11 KNZ74377.1 - 3.4e-07 29.5 0.0 5.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.16 KNZ74377.1 - 1.5e-05 24.5 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.22 KNZ74378.1 - 1.7e-55 188.7 0.0 2.1e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KNZ74379.1 - 3e-21 75.8 53.2 7.4e-18 64.6 39.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Helitron_like_N PF14214.6 KNZ74380.1 - 4.7e-16 59.6 0.1 5.6e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ74380.1 - 0.014 15.4 0.3 0.015 15.2 0.3 1.1 1 0 0 1 1 1 0 Inovirus Gp2 RNase_H PF00075.24 KNZ74381.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.4 1 1 0 1 1 1 1 RNase H HypF_C PF17788.1 KNZ74382.1 - 0.16 12.7 4.8 0.77 10.5 0.7 2.4 2 0 0 2 2 2 0 HypF Kae1-like domain L71 PF02448.15 KNZ74382.1 - 0.19 12.2 3.8 1.9 9.0 2.5 2.3 2 0 0 2 2 2 0 L71 family p450 PF00067.22 KNZ74385.1 - 6.3e-72 242.8 0.0 7.1e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 URO-D PF01208.17 KNZ74386.1 - 6.7e-129 430.0 0.0 7.5e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Nod1 PF17114.5 KNZ74386.1 - 0.19 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DSPn PF14671.6 KNZ74387.1 - 3.3e-41 141.0 0.0 7e-40 136.7 0.0 2.4 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KNZ74387.1 - 2.2e-13 50.1 0.0 4.2e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ74387.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KNZ74387.1 - 0.002 18.3 0.0 0.0035 17.5 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate UPF0731 PF14982.6 KNZ74387.1 - 0.033 14.4 1.7 37 4.6 2.2 3.5 3 0 0 3 3 3 0 UPF0731 family zf-RVT PF13966.6 KNZ74389.1 - 0.011 16.4 0.2 0.025 15.3 0.2 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Arf PF00025.21 KNZ74392.1 - 0.02 14.4 0.4 0.023 14.2 0.4 1.1 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF5344 PF17279.2 KNZ74392.1 - 0.022 15.3 0.5 0.033 14.7 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) zf-RVT PF13966.6 KNZ74395.1 - 3.9e-08 33.9 2.5 3.9e-08 33.9 2.5 1.9 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase KDZ PF18758.1 KNZ74397.1 - 5.5e-18 65.4 0.1 1.1e-17 64.5 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KNZ74397.1 - 1.5e-07 31.5 0.9 1.5e-07 31.5 0.9 2.1 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KNZ74397.1 - 3e-05 24.1 2.2 3.8e-05 23.8 0.9 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Peptidase_C48 PF02902.19 KNZ74397.1 - 0.0002 21.3 1.8 0.00043 20.2 1.8 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_S17e PF00833.18 KNZ74397.1 - 0.12 12.3 0.5 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal S17 vMSA PF00695.19 KNZ74404.1 - 0.21 10.6 0.4 0.27 10.3 0.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus MDM10 PF12519.8 KNZ74406.1 - 2.3e-86 290.6 1.6 3.5e-75 253.7 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 KNZ74406.1 - 0.11 11.9 0.0 10 5.5 0.0 3.0 2 1 0 3 3 3 0 Eukaryotic porin LSM PF01423.22 KNZ74408.1 - 9.8e-19 66.8 0.0 1.1e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KNZ74408.1 - 0.055 13.1 0.1 0.066 12.9 0.1 1.2 1 0 0 1 1 1 0 Hfq protein PPR_2 PF13041.6 KNZ74409.1 - 0.0011 19.2 0.0 0.91 9.8 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 KNZ74409.1 - 0.027 14.5 0.0 0.082 13.0 0.0 1.9 1 0 0 1 1 1 0 Pentatricopeptide repeat domain AAA PF00004.29 KNZ74410.1 - 1.5e-30 106.3 0.0 2.1e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ74410.1 - 8.6e-10 39.0 0.0 2e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ74410.1 - 2.8e-08 34.3 0.2 7.4e-08 33.0 0.2 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KNZ74410.1 - 4.1e-06 26.8 0.0 5.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 KNZ74410.1 - 1.2e-05 25.8 0.0 1.8e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KNZ74410.1 - 2.7e-05 24.3 0.0 5.2e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KNZ74410.1 - 7.6e-05 22.9 0.0 0.00017 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ74410.1 - 8e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KNZ74410.1 - 0.00011 22.2 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KNZ74410.1 - 0.00019 21.1 0.4 0.029 14.0 0.4 2.2 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 KNZ74410.1 - 0.00022 21.2 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KNZ74410.1 - 0.00029 20.9 0.1 0.00071 19.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KNZ74410.1 - 0.00045 20.2 0.0 0.00088 19.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KNZ74410.1 - 0.00049 19.3 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KNZ74410.1 - 0.00074 19.3 0.1 0.003 17.3 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 KNZ74410.1 - 0.00075 19.4 0.3 0.0016 18.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KNZ74410.1 - 0.00086 18.6 0.0 0.33 10.2 0.0 2.2 1 1 0 2 2 2 1 KAP family P-loop domain Cytidylate_kin PF02224.18 KNZ74410.1 - 0.0011 18.7 0.0 0.0022 17.8 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase RNA_helicase PF00910.22 KNZ74410.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 KNZ74410.1 - 0.0018 18.5 0.0 0.0044 17.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.9 KNZ74410.1 - 0.0022 17.3 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KNZ74410.1 - 0.0024 17.6 0.0 0.0078 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KNZ74410.1 - 0.0024 17.6 0.0 0.0081 15.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 KNZ74410.1 - 0.0034 16.7 0.0 0.0043 16.3 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain Viral_helicase1 PF01443.18 KNZ74410.1 - 0.0037 17.0 0.1 0.022 14.5 0.1 2.0 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 KNZ74410.1 - 0.0039 16.7 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 KNZ74410.1 - 0.0055 16.2 0.0 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 KNZ74410.1 - 0.0066 16.8 0.2 0.034 14.5 0.2 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KNZ74410.1 - 0.013 16.1 0.0 0.016 15.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 KNZ74410.1 - 0.016 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KNZ74410.1 - 0.017 15.6 0.0 0.049 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 KNZ74410.1 - 0.022 14.7 0.1 0.067 13.1 0.1 1.7 1 1 1 2 2 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KNZ74410.1 - 0.023 14.1 0.1 0.062 12.7 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 KNZ74410.1 - 0.028 13.8 0.0 0.7 9.2 0.0 2.2 2 0 0 2 2 2 0 KaiC ATP_bind_1 PF03029.17 KNZ74410.1 - 0.033 14.0 0.1 0.65 9.7 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CPT PF07931.12 KNZ74410.1 - 0.037 13.9 0.0 0.072 12.9 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.10 KNZ74410.1 - 0.04 13.3 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KNZ74410.1 - 0.049 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KNZ74410.1 - 0.07 13.0 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 NTPase Zot PF05707.12 KNZ74410.1 - 0.076 12.6 0.0 0.39 10.3 0.0 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) SRP54 PF00448.22 KNZ74410.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 KNZ74410.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 KNZ74410.1 - 0.11 12.4 0.2 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KNZ74410.1 - 0.11 13.0 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KNZ74410.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.23 KNZ74410.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.15 KNZ74410.1 - 0.15 12.1 0.0 2.3 8.2 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 KNZ74410.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_6 PF12774.7 KNZ74410.1 - 0.15 11.0 0.1 0.45 9.4 0.0 1.8 2 1 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_13 PF13166.6 KNZ74410.1 - 0.27 9.8 0.0 0.34 9.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rdx PF10262.9 KNZ74411.1 - 3.7e-23 81.5 0.0 7.5e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Rdx family CLASP_N PF12348.8 KNZ74412.1 - 3.9e-68 229.4 1.1 1.1e-61 208.3 0.3 4.0 4 0 0 4 4 4 2 CLASP N terminal HEAT PF02985.22 KNZ74412.1 - 2.1e-07 30.6 0.9 7 7.2 0.0 5.6 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 KNZ74412.1 - 2.2e-05 24.5 0.1 0.69 9.9 0.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KNZ74412.1 - 0.18 12.3 5.9 19 5.9 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Rhomboid PF01694.22 KNZ74413.1 - 6.9e-25 87.8 9.7 1.1e-24 87.2 9.7 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KNZ74413.1 - 0.011 16.2 0.3 0.011 16.2 0.3 1.8 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Microvir_lysis PF04517.12 KNZ74413.1 - 0.036 14.0 0.5 0.036 14.0 0.5 2.0 2 0 0 2 2 2 0 Microvirus lysis protein (E), C terminus Sedlin_N PF04628.13 KNZ74414.1 - 2.4e-24 85.9 0.1 1.4e-23 83.4 0.1 1.9 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 KNZ74414.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family Activator_LAG-3 PF11498.8 KNZ74415.1 - 8 5.3 28.1 14 4.5 28.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Actin PF00022.19 KNZ74416.1 - 8.2e-92 307.9 0.0 1e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KNZ74416.1 - 6.4e-05 21.9 0.0 0.14 10.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BOP1NT PF08145.12 KNZ74417.1 - 2.8e-92 309.3 4.7 4.3e-92 308.7 4.7 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KNZ74417.1 - 2e-19 69.6 7.0 0.00032 21.4 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ74417.1 - 1.4e-05 25.3 0.3 1.3 9.4 0.1 4.8 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain FCP1_C PF09309.10 KNZ74417.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.6 2 1 0 2 2 2 0 FCP1, C-terminal DUF2651 PF10852.8 KNZ74418.1 - 0.14 12.8 0.3 0.14 12.8 0.3 4.1 4 1 0 5 5 5 0 Protein of unknown function (DUF2651) TctB PF07331.11 KNZ74418.1 - 2.3 8.5 10.5 0.12 12.6 0.5 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF2423 PF10338.9 KNZ74419.1 - 1.5e-15 57.2 4.0 1.5e-15 57.2 4.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 KNZ74419.1 - 0.047 14.3 0.7 0.047 14.3 0.7 1.5 2 0 0 2 2 2 0 Learning-associated protein LSM PF01423.22 KNZ74420.1 - 1.4e-20 72.7 0.0 1.6e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KNZ74420.1 - 0.0041 17.2 0.0 0.0046 17.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 KNZ74421.1 - 1.1e-19 70.4 0.8 1.6e-19 69.9 0.8 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 KNZ74421.1 - 0.00081 19.4 0.1 0.001 19.0 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 KNZ74421.1 - 0.017 15.5 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PfkB PF00294.24 KNZ74422.1 - 6.4e-10 38.8 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KNZ74422.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase ACPS PF01648.20 KNZ74423.1 - 1.3e-09 38.2 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily RNA_pol_Rpc34 PF05158.12 KNZ74424.1 - 4.6e-70 236.6 0.0 2.9e-68 230.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit CCDC71L PF15374.6 KNZ74424.1 - 3.6e-06 26.5 0.3 3.6e-06 26.5 0.3 1.6 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 71L B-block_TFIIIC PF04182.12 KNZ74424.1 - 0.021 15.0 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC HxlR PF01638.17 KNZ74424.1 - 0.038 13.8 0.1 0.073 12.9 0.1 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Macoilin PF09726.9 KNZ74424.1 - 0.94 8.0 14.0 1.3 7.5 14.0 1.1 1 0 0 1 1 1 0 Macoilin family Asp_protease_2 PF13650.6 KNZ74426.1 - 0.00082 20.0 0.0 0.0013 19.4 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ74426.1 - 0.0012 19.4 0.0 0.0019 18.7 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Helitron_like_N PF14214.6 KNZ74429.1 - 1.5e-17 64.4 0.1 1.9e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ74429.1 - 0.13 12.2 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Inovirus Gp2 PIF1 PF05970.14 KNZ74430.1 - 1.9e-63 214.8 0.1 2.8e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74430.1 - 5e-05 23.1 0.0 7.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ74430.1 - 0.0071 16.4 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ74430.1 - 0.02 15.3 0.0 0.035 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ74430.1 - 0.032 14.0 0.2 0.077 12.7 0.2 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NAAA-beta PF15508.6 KNZ74430.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MADF_DNA_bdg PF10545.9 KNZ74430.1 - 0.18 12.1 0.4 0.72 10.2 0.0 2.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PIF1 PF05970.14 KNZ74431.1 - 3.3e-29 102.2 0.2 3.8e-29 102.0 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase Pkr1 PF08636.10 KNZ74432.1 - 1.2e-14 54.2 8.8 1.5e-14 53.9 8.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4191 PF13829.6 KNZ74432.1 - 0.0027 17.1 0.4 0.0028 17.0 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) Spore_YabQ PF09578.10 KNZ74432.1 - 0.0042 17.3 1.9 0.0053 16.9 1.9 1.2 1 0 0 1 1 1 1 Spore cortex protein YabQ (Spore_YabQ) Sld5 PF05916.11 KNZ74433.1 - 0.00043 20.7 0.0 0.00067 20.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Tau95 PF09734.9 KNZ74435.1 - 8.8e-34 117.3 0.4 7.1e-33 114.4 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KNZ74435.1 - 1.3e-26 93.2 0.0 2.8e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain zf-HC2 PF13490.6 KNZ74438.1 - 0.29 11.4 0.4 0.93 9.8 0.0 2.1 3 0 0 3 3 3 0 Putative zinc-finger Aconitase PF00330.20 KNZ74439.1 - 9.3e-160 532.6 0.0 1.1e-159 532.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KNZ74439.1 - 5.8e-40 136.6 0.0 9.5e-40 136.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain ALF PF03752.13 KNZ74439.1 - 0.5 10.4 3.3 11 6.0 0.2 2.5 2 0 0 2 2 2 0 Short repeats of unknown function Glyco_hydro_125 PF06824.11 KNZ74441.1 - 4.9e-149 496.7 0.0 5.7e-149 496.5 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) C2 PF00168.30 KNZ74442.1 - 4.2e-13 49.5 0.0 2.3e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain WD40 PF00400.32 KNZ74443.1 - 2e-11 44.2 3.5 0.0072 17.1 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat EF-hand_13 PF17958.1 KNZ74443.1 - 0.02 14.7 0.0 0.064 13.1 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain ANAPC4_WD40 PF12894.7 KNZ74443.1 - 0.025 14.9 0.1 1.5 9.2 0.1 2.4 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain dUTPase PF00692.19 KNZ74444.1 - 4.6e-33 113.7 0.0 7.7e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 dUTPase Exo_endo_phos_2 PF14529.6 KNZ74446.1 - 2.9e-09 36.8 0.1 5.6e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KNZ74446.1 - 1e-08 35.4 0.0 6e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 RNase H zf-RVT PF13966.6 KNZ74446.1 - 3.4e-07 30.9 0.1 8.5e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Exo_endo_phos PF03372.23 KNZ74446.1 - 0.00032 20.3 0.1 0.0007 19.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3336 PF11815.8 KNZ74447.1 - 6.7e-52 174.9 0.3 1e-51 174.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KNZ74447.1 - 7e-18 65.5 0.1 1.5e-17 64.5 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TadE PF07811.12 KNZ74447.1 - 0.71 10.2 4.0 1.5 9.1 4.0 1.5 1 0 0 1 1 1 0 TadE-like protein DUF3759 PF12585.8 KNZ74448.1 - 8.2e-39 131.5 8.5 9.6e-39 131.3 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) PCSK9_C2 PF18464.1 KNZ74449.1 - 0.031 14.3 1.4 2.3 8.3 0.0 3.3 3 0 0 3 3 3 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain ORC4_C PF14629.6 KNZ74450.1 - 9e-31 106.9 0.2 1.6e-30 106.1 0.2 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KNZ74450.1 - 4.1e-17 63.1 0.1 9.3e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KNZ74450.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 KNZ74450.1 - 0.008 16.1 0.0 2.5 8.0 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KNZ74450.1 - 0.009 16.3 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KNZ74450.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KNZ74450.1 - 0.075 13.5 0.0 0.22 12.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KNZ74450.1 - 0.085 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 KNZ74450.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 KNZ74450.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Med20 PF08612.11 KNZ74451.1 - 1.2e-08 34.6 0.0 4.2e-08 32.8 0.0 1.7 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Phage_holin_3_6 PF07332.11 KNZ74453.1 - 4.4 7.4 8.1 2.1 8.4 0.7 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III zf-CCHC PF00098.23 KNZ74456.1 - 0.72 10.0 3.8 1.1 9.5 3.8 1.3 1 0 0 1 1 1 0 Zinc knuckle Sugar_tr PF00083.24 KNZ74458.1 - 7.8e-22 77.7 0.2 9.6e-22 77.5 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KNZ74458.1 - 0.076 11.4 0.6 0.098 11.0 0.6 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KNZ74458.1 - 0.089 11.7 2.1 0.17 10.7 2.1 1.4 1 1 0 1 1 1 0 Major Facilitator Superfamily HLH PF00010.26 KNZ74459.1 - 4.1e-07 29.9 0.0 6.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Atrophin-1 PF03154.15 KNZ74461.1 - 0.00062 18.2 14.8 0.00062 18.2 14.8 1.6 1 1 1 2 2 2 1 Atrophin-1 family DUF3915 PF13054.6 KNZ74461.1 - 0.0074 16.3 12.9 0.017 15.1 12.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) Auts2 PF15336.6 KNZ74461.1 - 0.64 10.1 7.6 1.3 9.1 7.6 1.6 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Phage_Gp23 PF10669.9 KNZ74461.1 - 1.8 8.9 6.4 3.3 8.1 6.4 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Trypan_PARP PF05887.11 KNZ74461.1 - 6 6.8 22.1 3 7.8 4.2 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ceramidase_alk PF04734.13 KNZ74462.1 - 1.5e-69 235.0 0.0 7.2e-40 137.1 0.1 2.3 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KNZ74462.1 - 7.7e-50 169.0 0.1 1.3e-49 168.3 0.1 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RVT_1 PF00078.27 KNZ74462.1 - 0.053 13.0 0.2 0.48 9.9 0.2 2.1 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TGT_C2 PF14810.6 KNZ74464.1 - 0.026 14.6 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Plavaka PF18759.1 KNZ74465.1 - 3.1e-11 43.1 0.0 6.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Plavaka transposase Asp_protease_2 PF13650.6 KNZ74466.1 - 0.0051 17.4 0.0 0.0071 17.0 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ74466.1 - 0.036 14.6 0.0 0.056 14.0 0.0 1.3 1 1 0 1 1 1 0 gag-polyprotein putative aspartyl protease UbiA PF01040.18 KNZ74469.1 - 2.4e-06 27.0 0.3 3.2e-06 26.6 0.2 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF1564 PF07600.11 KNZ74469.1 - 0.14 11.8 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) PP-binding PF00550.25 KNZ74470.1 - 1.2e-14 54.4 4.5 4.5e-08 33.3 0.5 2.3 2 0 0 2 2 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 KNZ74471.1 - 3.6e-29 102.3 0.0 5.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 KNZ74471.1 - 1.3e-21 77.2 0.0 2e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KNZ74471.1 - 0.0002 21.8 0.0 0.00078 19.9 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Aminotran_5 PF00266.19 KNZ74473.1 - 3.6e-11 42.6 0.0 3.7e-10 39.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KNZ74473.1 - 0.0091 15.3 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Chromo PF00385.24 KNZ74474.1 - 1e-05 25.3 0.2 1.6e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Methyltransf_2 PF00891.18 KNZ74475.1 - 2.8e-24 85.6 0.0 4.8e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KNZ74475.1 - 1e-05 25.4 0.0 2.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 KNZ74475.1 - 3.9e-05 23.1 0.1 7.2e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KNZ74475.1 - 0.00019 22.1 0.0 0.00054 20.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ74475.1 - 0.00021 21.9 0.0 0.00072 20.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KNZ74475.1 - 0.00061 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KNZ74475.1 - 0.04 14.5 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ74475.1 - 0.053 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 KNZ74475.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PIF1 PF05970.14 KNZ74476.1 - 5.4e-95 318.6 0.1 1.2e-75 255.0 0.0 2.0 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KNZ74476.1 - 1.1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ74476.1 - 0.0061 17.0 0.0 0.01 16.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain 4HPAD_g_N PF18671.1 KNZ74476.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal ResIII PF04851.15 KNZ74476.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ74476.1 - 0.073 12.8 0.2 0.16 11.7 0.2 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 KNZ74476.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF2791 PF10923.8 KNZ74476.1 - 0.16 10.8 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) FAM60A PF15396.6 KNZ74477.1 - 0.21 11.5 7.4 0.27 11.2 7.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A MAP17 PF15807.5 KNZ74477.1 - 0.41 10.9 9.2 0.5 10.6 9.2 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 HGTP_anticodon2 PF12745.7 KNZ74477.1 - 0.9 9.0 9.4 1.4 8.4 9.0 1.4 1 1 0 1 1 1 0 Anticodon binding domain of tRNAs DUF913 PF06025.12 KNZ74477.1 - 1.1 8.1 4.1 1.4 7.8 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tub_N PF16322.5 KNZ74477.1 - 1.3 9.4 14.4 1.6 9.1 14.4 1.1 1 0 0 1 1 1 0 Tubby N-terminal Zip PF02535.22 KNZ74477.1 - 1.9 7.6 5.7 2.1 7.5 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 KNZ74477.1 - 7.6 5.3 11.7 9.8 4.9 11.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.16 KNZ74477.1 - 8.7 5.8 10.4 10 5.5 10.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 KNZ74477.1 - 9.1 4.9 6.9 11 4.7 6.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 KNZ74477.1 - 9.3 5.6 13.2 12 5.3 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) NPR3 PF03666.13 KNZ74477.1 - 9.8 4.8 8.3 11 4.6 8.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_28 PF13521.6 KNZ74479.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ca_chan_IQ PF08763.11 KNZ74481.1 - 0.05 13.8 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain NCD3G PF07562.14 KNZ74482.1 - 1.2 9.1 11.5 0.27 11.2 6.9 2.0 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR His_Phos_2 PF00328.22 KNZ74483.1 - 6.4e-45 154.1 0.0 8.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MAM1 PF10434.9 KNZ74484.1 - 0.0096 15.6 0.1 0.027 14.1 0.0 1.6 2 0 0 2 2 2 1 Monopolin complex protein MAM1 Mucin15 PF15672.5 KNZ74484.1 - 0.022 14.3 13.8 0.041 13.4 13.8 1.5 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 Gly-zipper_Omp PF13488.6 KNZ74484.1 - 0.031 14.3 0.1 0.051 13.6 0.1 1.2 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 KNZ74484.1 - 0.1 12.5 2.1 0.18 11.7 2.1 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF4538 PF15061.6 KNZ74484.1 - 1.8 8.3 3.5 3.6 7.4 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Adeno_E3_CR2 PF02439.15 KNZ74485.1 - 0.0023 17.6 0.8 0.0049 16.6 0.8 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 ATG16 PF08614.11 KNZ74485.1 - 0.02 15.1 0.1 0.02 15.1 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF5305 PF17231.2 KNZ74485.1 - 0.03 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Yip1 PF04893.17 KNZ74485.1 - 0.035 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Yip1 domain Gly-zipper_Omp PF13488.6 KNZ74485.1 - 0.11 12.5 3.2 0.19 11.8 3.2 1.3 1 0 0 1 1 1 0 Glycine zipper DivIC PF04977.15 KNZ74485.1 - 0.18 11.6 7.8 0.72 9.7 0.5 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 KNZ74485.1 - 0.35 10.2 2.0 0.64 9.3 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2937 PF11157.8 KNZ74485.1 - 2.6 7.7 5.3 6.3 6.5 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) ABC_tran_CTD PF16326.5 KNZ74485.1 - 4.7 7.5 6.7 0.98 9.7 1.2 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain Pyr_redox_2 PF07992.14 KNZ74486.1 - 0.00017 20.9 0.0 0.13 11.5 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ74486.1 - 0.002 18.6 0.0 0.0044 17.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ74486.1 - 0.038 13.1 0.0 3.7 6.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 KNZ74486.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIA PF03153.13 KNZ74487.1 - 0.0048 17.0 8.6 0.0059 16.7 8.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit gag-asp_proteas PF13975.6 KNZ74488.1 - 0.0011 19.5 0.0 0.0033 18.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ74488.1 - 0.0015 19.2 0.0 0.0047 17.5 0.0 1.9 1 0 0 1 1 1 1 Aspartyl protease DUF3446 PF11928.8 KNZ74488.1 - 6.3 7.2 9.8 50 4.3 8.1 2.4 1 1 1 2 2 2 0 Early growth response N-terminal domain RT_RNaseH PF17917.1 KNZ74489.1 - 6.5e-08 32.8 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ74489.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KNZ74490.1 - 2.5e-12 46.7 0.5 4e-12 46.0 0.5 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Asp_protease_2 PF13650.6 KNZ74491.1 - 0.0001 22.8 0.0 0.00026 21.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ74491.1 - 0.00019 21.9 0.0 0.00037 21.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease PIF1 PF05970.14 KNZ74492.1 - 2.4e-36 125.7 0.0 2.7e-36 125.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74492.1 - 0.0032 17.2 0.0 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ74492.1 - 0.0042 16.9 0.1 0.011 15.5 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ74492.1 - 0.035 14.5 0.1 0.16 12.4 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KNZ74492.1 - 0.052 13.1 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KNZ74492.1 - 0.064 13.2 0.0 0.29 11.1 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ74492.1 - 0.084 13.3 0.0 0.084 13.2 0.0 1.2 1 1 0 1 1 1 0 AAA ATPase domain Torsin PF06309.11 KNZ74492.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin Helitron_like_N PF14214.6 KNZ74493.1 - 2.9e-64 216.8 0.6 4.9e-64 216.1 0.1 1.7 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ74493.1 - 0.042 12.9 1.2 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) TFIIA PF03153.13 KNZ74494.1 - 0.069 13.1 8.1 0.092 12.7 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 KNZ74494.1 - 7.7 4.9 16.4 11 4.4 16.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fmp27_SW PF10305.9 KNZ74496.1 - 0.16 12.7 0.0 4.1 8.2 0.0 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Integrase_H2C2 PF17921.1 KNZ74497.1 - 9.3e-12 44.9 2.6 9.3e-12 44.9 2.6 1.8 2 0 0 2 2 2 1 Integrase zinc binding domain WCCH PF03716.14 KNZ74497.1 - 0.013 15.2 0.9 0.013 15.2 0.9 1.9 2 0 0 2 2 2 0 WCCH motif DUF5017 PF16409.5 KNZ74500.1 - 0.12 11.9 0.3 0.18 11.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) HA2 PF04408.23 KNZ74501.1 - 5.4e-18 65.3 0.0 1.4e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KNZ74501.1 - 1.8e-12 47.6 0.0 7e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KNZ74501.1 - 6.6e-10 39.2 0.0 2.5e-09 37.4 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KNZ74501.1 - 9.5e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KNZ74501.1 - 0.00014 22.1 0.1 0.00037 20.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ74501.1 - 0.00047 19.9 0.1 0.0011 18.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 KNZ74501.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 KNZ74501.1 - 0.001 19.4 0.1 0.0021 18.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ74501.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 KNZ74501.1 - 0.027 14.3 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Helicase ABC_tran PF00005.27 KNZ74501.1 - 0.032 14.8 0.3 0.43 11.1 0.3 2.5 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 KNZ74501.1 - 0.042 13.3 0.1 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 KNZ74501.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 KaiC ATPase_2 PF01637.18 KNZ74501.1 - 0.14 12.1 0.2 4.9 7.0 0.0 2.8 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 KNZ74501.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 KNZ74501.1 - 0.15 12.0 0.1 1 9.3 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KNZ74501.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glyco_hydro_18 PF00704.28 KNZ74502.1 - 4.5e-16 59.5 0.5 8.4e-16 58.6 0.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 RT_RNaseH PF17917.1 KNZ74504.1 - 5.8e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ74504.1 - 0.036 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Glyco_hydro_18 PF00704.28 KNZ74506.1 - 1.9e-15 57.4 1.0 4.5e-15 56.2 1.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LMBR1 PF04791.16 KNZ74507.1 - 0.00029 19.9 0.9 0.00039 19.5 0.9 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Spc7 PF08317.11 KNZ74507.1 - 0.011 14.7 1.6 0.014 14.3 1.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 KNZ74507.1 - 0.013 15.5 4.9 0.019 15.0 4.9 1.2 1 0 0 1 1 1 0 Laminin Domain II Cortex-I_coil PF09304.10 KNZ74507.1 - 0.019 15.2 2.3 21 5.4 0.5 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil TMPIT PF07851.13 KNZ74507.1 - 0.02 14.2 4.0 0.03 13.6 4.0 1.3 1 1 0 1 1 1 0 TMPIT-like protein AAA_32 PF13654.6 KNZ74507.1 - 0.028 13.2 0.3 0.033 13.0 0.3 1.1 1 0 0 1 1 1 0 AAA domain AIP3 PF03915.13 KNZ74507.1 - 0.028 13.5 1.9 0.034 13.2 1.9 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 SPATIAL PF15256.6 KNZ74507.1 - 0.044 14.1 1.5 0.061 13.6 1.5 1.2 1 0 0 1 1 1 0 SPATIAL DUF745 PF05335.13 KNZ74507.1 - 0.12 12.1 2.6 0.17 11.6 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 KNZ74507.1 - 0.13 11.8 3.4 0.16 11.5 3.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Latarcin PF10279.9 KNZ74507.1 - 0.13 12.7 0.7 0.23 11.9 0.7 1.5 1 0 0 1 1 1 0 Latarcin precursor Prominin PF05478.11 KNZ74507.1 - 0.2 9.5 1.1 0.27 9.1 1.1 1.2 1 0 0 1 1 1 0 Prominin Tropomyosin PF00261.20 KNZ74507.1 - 0.95 8.8 7.4 3.7 6.9 6.4 2.0 1 1 0 1 1 1 0 Tropomyosin Fib_alpha PF08702.10 KNZ74507.1 - 0.97 9.6 5.1 1.9 8.7 5.1 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Vps5 PF09325.10 KNZ74508.1 - 5e-72 242.3 5.2 6.4e-72 241.9 5.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KNZ74508.1 - 3.1e-25 88.4 0.2 4.2e-24 84.7 0.0 2.2 2 0 0 2 2 2 1 PX domain BAR PF03114.18 KNZ74508.1 - 1.8e-05 24.5 2.8 2.7e-05 24.0 2.8 1.2 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.9 KNZ74508.1 - 0.00091 18.8 1.4 0.13 11.7 0.2 2.2 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.13 KNZ74508.1 - 0.0013 18.3 2.7 0.0026 17.3 2.7 1.4 1 1 0 1 1 1 1 Arfaptin-like domain BAR_3 PF16746.5 KNZ74508.1 - 0.028 14.1 3.3 0.089 12.5 0.3 2.1 2 0 0 2 2 2 0 BAR domain of APPL family FAM92 PF06730.11 KNZ74508.1 - 0.15 11.4 5.7 0.33 10.3 5.7 1.4 1 1 0 1 1 1 0 FAM92 protein DNA_pack_N PF02500.15 KNZ74508.1 - 0.16 11.8 0.8 0.41 10.4 0.3 1.8 1 1 1 2 2 2 0 Probable DNA packing protein, N-terminus CLZ PF16526.5 KNZ74508.1 - 0.42 11.0 1.6 1.1 9.7 0.1 2.4 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DWNN PF08783.11 KNZ74509.1 - 1.6e-28 98.8 1.9 1.8e-28 98.7 0.1 2.0 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 KNZ74509.1 - 7.9e-11 41.6 6.5 1.4e-10 40.8 6.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KNZ74509.1 - 1.9e-06 27.7 1.6 3.6e-06 26.8 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ74509.1 - 0.0025 17.7 0.2 0.0053 16.7 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 KNZ74509.1 - 0.003 17.7 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 U-box domain RHH_3 PF12651.7 KNZ74509.1 - 0.011 15.7 1.1 0.11 12.5 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain zf-C3HC4_3 PF13920.6 KNZ74509.1 - 0.012 15.4 5.5 0.012 15.4 5.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ74509.1 - 0.015 15.1 8.4 0.015 15.1 8.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.6 KNZ74509.1 - 0.025 14.3 0.6 0.025 14.3 0.6 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-RING_UBOX PF13445.6 KNZ74509.1 - 0.094 12.8 6.7 0.2 11.7 6.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger TFB6 PF17110.5 KNZ74509.1 - 0.16 11.7 1.1 0.34 10.6 1.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH zf-C3HC4 PF00097.25 KNZ74509.1 - 1.2 9.0 8.4 2.7 7.9 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ74509.1 - 1.4 8.9 12.1 0.18 11.8 6.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 KNZ74509.1 - 1.8 9.0 13.4 0.044 14.1 6.9 1.7 2 0 0 2 2 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KNZ74509.1 - 2.4 8.4 8.9 5.8 7.2 8.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING ERG4_ERG24 PF01222.17 KNZ74510.1 - 1.6e-119 399.5 23.7 2e-119 399.2 23.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family TPR_19 PF14559.6 KNZ74511.1 - 1.4e-08 35.1 1.6 0.0017 18.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74511.1 - 2.1e-08 33.7 0.0 0.056 13.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74511.1 - 5.9e-08 33.2 0.2 0.0012 19.4 0.0 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ74511.1 - 5e-07 29.9 0.0 0.28 11.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ74511.1 - 5.2e-07 29.9 5.5 1.1 10.3 0.0 5.9 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ74511.1 - 7.5e-06 25.6 0.0 1 9.5 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ74511.1 - 8.6e-06 25.6 0.0 0.86 10.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ74511.1 - 2.6e-05 23.8 0.0 0.24 11.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ74511.1 - 4.6e-05 23.5 0.1 0.0042 17.4 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ74511.1 - 8.1e-05 22.4 0.1 0.29 11.1 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ74511.1 - 0.00024 21.3 0.0 0.045 14.0 0.0 2.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 KNZ74511.1 - 0.0072 16.0 0.1 0.028 14.2 0.0 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 KNZ74511.1 - 0.025 14.7 0.5 8.1 6.7 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 KNZ74511.1 - 0.035 13.8 0.0 4.9 6.8 0.0 2.5 1 1 1 2 2 2 0 26S proteasome subunit RPN7 HemY_N PF07219.13 KNZ74511.1 - 0.035 14.3 0.0 0.19 11.9 0.0 2.2 1 1 1 2 2 2 0 HemY protein N-terminus DUF1955 PF09205.10 KNZ74511.1 - 0.089 12.5 0.5 0.56 9.9 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1955) TPR_11 PF13414.6 KNZ74511.1 - 0.18 11.5 0.1 24 4.7 0.0 3.1 3 1 1 4 4 4 0 TPR repeat KAR9 PF08580.10 KNZ74512.1 - 8.4e-20 70.9 32.6 5.3e-18 65.0 32.6 3.0 1 1 0 1 1 1 1 Yeast cortical protein KAR9 GAS2 PF02187.17 KNZ74512.1 - 6.3e-05 23.0 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Med4 PF10018.9 KNZ74512.1 - 0.0085 15.8 0.5 0.093 12.4 0.0 2.5 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF3479 PF11965.8 KNZ74512.1 - 0.027 14.6 0.3 0.093 12.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) RIC3 PF15361.6 KNZ74512.1 - 0.14 12.6 2.5 3.2 8.1 0.4 3.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FlaC_arch PF05377.11 KNZ74512.1 - 7.7 7.0 7.4 4.4 7.8 0.5 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Clr2_transil PF16761.5 KNZ74513.1 - 1.1e-23 83.8 0.9 3.1e-23 82.4 0.9 1.8 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KNZ74513.1 - 2.3e-06 28.4 0.0 0.00023 22.0 0.0 2.7 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 MBOAT PF03062.19 KNZ74514.1 - 1.9e-14 53.8 25.5 5.7e-12 45.6 5.5 3.1 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KNZ74514.1 - 0.0073 16.6 0.9 0.038 14.3 0.1 2.5 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family Sds3 PF08598.11 KNZ74515.1 - 1.4e-06 28.5 2.5 1.7e-06 28.2 2.5 1.4 1 1 0 1 1 1 1 Sds3-like F-box-like PF12937.7 KNZ74516.1 - 2.2e-05 24.3 0.0 5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ74516.1 - 3.3e-05 23.6 0.4 7.5e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KNZ74516.1 - 0.091 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box DnaJ PF00226.31 KNZ74517.1 - 4.3e-25 87.6 0.5 7.1e-25 86.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 KNZ74517.1 - 8.9e-21 74.1 0.0 1.9e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) hGDE_N PF14699.6 KNZ74518.1 - 0.058 13.5 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme WD40 PF00400.32 KNZ74519.1 - 1.9e-08 34.8 3.9 0.91 10.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Carm_PH PF17888.1 KNZ74519.1 - 0.17 12.3 0.8 27 5.2 0.0 2.8 2 1 1 3 3 3 0 Carmil pleckstrin homology domain Pkinase_Tyr PF07714.17 KNZ74520.1 - 1.4e-26 93.3 0.0 2.4e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74520.1 - 7e-23 81.3 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain PAM2 PF07145.15 KNZ74520.1 - 0.0011 18.6 0.0 0.26 11.1 0.0 2.9 2 0 0 2 2 2 2 Ataxin-2 C-terminal region DOPA_dioxygen PF08883.11 KNZ74523.1 - 1.5e-21 76.6 0.0 1.9e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family FGF-BP1 PF06473.12 KNZ74524.1 - 2 8.2 6.6 0.82 9.5 1.7 2.0 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) SWIRM-assoc_2 PF16496.5 KNZ74524.1 - 4.2 6.1 14.6 0.15 10.9 8.1 1.6 1 1 1 2 2 2 0 SWIRM-associated domain at the N-terminal StbA PF06406.11 KNZ74526.1 - 0.11 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 StbA protein DUF1804 PF08822.11 KNZ74529.1 - 0.055 13.4 0.1 0.055 13.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) TFIIS_M PF07500.14 KNZ74530.1 - 1.3e-15 57.8 0.8 2.5e-15 56.9 0.8 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 KNZ74530.1 - 7.5e-13 48.7 0.0 5.6e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 SPOC domain PHD PF00628.29 KNZ74530.1 - 4.7e-10 39.2 7.7 8.1e-10 38.4 7.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KNZ74530.1 - 0.61 9.7 2.4 1.2 8.8 2.4 1.5 1 0 0 1 1 1 0 PHD-finger ADH_zinc_N PF00107.26 KNZ74531.1 - 4.5e-14 52.5 0.0 6e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ74531.1 - 3.1e-08 33.5 0.0 1e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KNZ74531.1 - 6.6e-05 22.5 0.1 0.00037 20.0 0.1 2.0 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pkinase PF00069.25 KNZ74532.1 - 3.4e-56 190.5 0.0 3.5e-55 187.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74532.1 - 3.1e-25 88.9 0.1 1.6e-19 70.2 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ74532.1 - 8.7e-06 24.9 0.2 1.5e-05 24.1 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KNZ74532.1 - 0.0042 16.4 0.1 0.0087 15.4 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ74532.1 - 0.0051 16.8 0.4 0.2 11.5 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ74532.1 - 0.0061 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 KNZ74532.1 - 0.01 15.2 0.5 0.029 13.7 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KNZ74532.1 - 0.04 12.7 0.9 0.058 12.2 1.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KNZ74532.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KNZ74533.1 - 1.8e-41 139.3 10.0 1.5e-07 32.0 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ74533.1 - 6.5e-14 52.0 0.0 0.089 13.1 0.0 5.7 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 KNZ74533.1 - 3.3e-13 48.9 1.0 6.5e-13 48.0 1.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 KNZ74533.1 - 3.6e-05 23.2 0.0 0.21 10.9 0.0 3.9 3 1 1 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 KNZ74533.1 - 0.00096 18.2 0.0 13 4.6 0.0 4.1 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KNZ74533.1 - 0.002 17.5 0.1 7.7 5.7 0.0 3.2 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KNZ74533.1 - 0.27 9.8 2.4 3.8 6.0 0.0 3.4 4 1 1 5 5 5 0 Nucleoporin Nup120/160 Ank_4 PF13637.6 KNZ74534.1 - 1.2e-11 44.9 0.2 1.6e-07 31.7 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ74534.1 - 2.3e-11 44.1 0.2 1.7e-05 25.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ74534.1 - 4.8e-10 39.5 0.4 0.0011 19.3 0.1 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ74534.1 - 1.4e-09 37.3 0.3 0.013 16.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KNZ74534.1 - 4.6e-09 36.3 2.5 0.0003 21.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.13 KNZ74534.1 - 0.00015 21.6 0.2 0.0034 17.2 0.2 2.3 1 1 0 1 1 1 1 KilA-N domain Spc29 PF17082.5 KNZ74534.1 - 0.065 13.1 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 Rootletin PF15035.6 KNZ74536.1 - 0.0037 17.3 0.2 0.007 16.4 0.2 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion PspA_IM30 PF04012.12 KNZ74536.1 - 0.14 11.7 3.0 0.43 10.1 1.0 2.2 2 0 0 2 2 2 0 PspA/IM30 family CENP-F_leu_zip PF10473.9 KNZ74536.1 - 0.47 10.5 4.3 0.84 9.7 4.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 KNZ74536.1 - 7.8 5.5 6.2 4.8 6.2 3.7 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 An_peroxidase PF03098.15 KNZ74537.1 - 1.7e-33 116.0 0.0 1.9e-21 76.2 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KNZ74537.1 - 0.00025 19.9 0.0 0.00046 19.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Coatomer_E PF04733.14 KNZ74538.1 - 5.8e-38 130.9 0.1 7.2e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KNZ74538.1 - 1.7e-05 25.2 2.7 8.8 6.9 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74538.1 - 0.00046 20.1 0.1 19 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ74538.1 - 0.0055 17.4 7.8 35 5.6 0.1 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ74538.1 - 0.0074 16.8 7.4 1.5 9.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ74538.1 - 0.035 14.7 0.1 61 4.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TetR_C_36 PF18598.1 KNZ74538.1 - 0.055 13.4 1.2 0.13 12.3 0.2 2.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_8 PF13181.6 KNZ74538.1 - 0.084 13.1 0.1 2.4 8.6 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74538.1 - 0.19 12.4 7.9 16 6.2 0.1 5.1 4 3 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ74538.1 - 0.24 11.6 2.2 0.89 9.7 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.7 KNZ74539.1 - 1.1e-12 47.6 0.5 2.9e-12 46.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like Vps62 PF06101.11 KNZ74540.1 - 4.4e-17 61.6 5.5 6.4e-17 61.1 5.5 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 PI3_PI4_kinase PF00454.27 KNZ74541.1 - 2.6e-52 178.1 0.0 5e-52 177.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KNZ74541.1 - 6.1e-10 38.7 0.0 2.1e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 FATC domain TAN PF11640.8 KNZ74541.1 - 2.9e-08 34.0 0.9 2.4e-07 31.0 0.1 3.1 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair DUF4407 PF14362.6 KNZ74541.1 - 0.17 11.2 0.6 0.42 9.9 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PALP PF00291.25 KNZ74542.1 - 5.7e-52 176.9 0.1 6.6e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 KNZ74543.1 - 5.6e-52 177.0 0.4 6.5e-52 176.8 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Asparaginase_C PF17763.1 KNZ74543.1 - 0.13 12.4 0.1 0.33 11.2 0.1 1.7 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain DOPA_dioxygen PF08883.11 KNZ74544.1 - 6.2e-46 155.0 1.2 7.8e-46 154.7 1.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family PH_10 PF15411.6 KNZ74545.1 - 2e-24 86.2 0.0 3.2e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KNZ74545.1 - 1.3e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KNZ74545.1 - 0.00013 22.3 1.6 0.00026 21.3 1.6 1.6 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.6 KNZ74545.1 - 0.00015 21.8 0.3 0.00052 20.0 0.0 2.1 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_UBOX PF13445.6 KNZ74545.1 - 0.00068 19.6 0.9 0.0017 18.3 0.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KNZ74545.1 - 0.003 17.5 1.3 0.0057 16.6 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 KNZ74545.1 - 0.27 11.0 5.4 0.22 11.3 3.3 2.1 2 0 0 2 2 2 0 RING-like zinc finger RRP7 PF12923.7 KNZ74546.1 - 2.7e-28 98.5 5.2 6.2e-28 97.3 5.2 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 KNZ74546.1 - 1.2e-10 41.4 0.2 3.1e-10 40.1 0.0 1.9 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 KNZ74546.1 - 2e-05 24.3 0.0 4.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myc_N PF01056.18 KNZ74546.1 - 0.068 13.1 7.0 0.077 12.9 3.3 2.0 1 1 0 2 2 2 0 Myc amino-terminal region PMT PF02366.18 KNZ74547.1 - 8.5e-84 281.0 16.1 1.5e-83 280.1 16.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KNZ74547.1 - 2.9e-63 213.1 2.9 2.9e-63 213.1 2.9 3.7 2 1 2 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KNZ74547.1 - 4.3e-17 62.6 1.6 7e-17 61.9 1.6 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KNZ74547.1 - 3.7e-07 30.5 12.9 1.3e-06 28.7 12.9 2.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Transport_MerF PF11431.8 KNZ74547.1 - 0.39 10.6 3.1 0.36 10.8 0.9 2.2 2 0 0 2 2 2 0 Membrane transport protein MerF PX PF00787.24 KNZ74548.1 - 4.9e-15 55.5 0.0 1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 PX domain IQCJ-SCHIP1 PF15157.6 KNZ74548.1 - 0.67 9.8 3.4 11 5.8 0.1 2.4 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DnaJ PF00226.31 KNZ74549.1 - 6.8e-14 51.7 0.3 6.8e-14 51.7 0.3 2.5 4 0 0 4 4 4 1 DnaJ domain DDHD PF02862.17 KNZ74549.1 - 2.6 8.1 6.2 0.76 9.9 3.4 1.5 2 0 0 2 2 2 0 DDHD domain E1-E2_ATPase PF00122.20 KNZ74550.1 - 1.2e-49 168.3 5.4 1.2e-49 168.3 5.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KNZ74550.1 - 1e-32 114.2 0.8 1.8e-32 113.4 0.3 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KNZ74550.1 - 4.6e-27 94.3 0.0 5.9e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KNZ74550.1 - 0.00024 20.9 0.4 0.033 13.9 0.3 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 KNZ74550.1 - 0.13 12.3 2.1 2.9 7.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) HAD PF12710.7 KNZ74550.1 - 0.13 12.7 0.3 1.8 8.9 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 KNZ74551.1 - 2.4e-60 204.6 0.7 1.1e-59 202.5 0.7 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.10 KNZ74551.1 - 0.2 12.0 0.3 0.46 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Dynactin_p22 PF07426.11 KNZ74552.1 - 1.8e-14 53.9 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 Sbi-IV PF11621.8 KNZ74552.1 - 0.0041 17.4 1.4 13 6.2 0.0 3.8 3 1 1 4 4 4 2 C3 binding domain 4 of IgG-bind protein SBI Lebercilin PF15619.6 KNZ74552.1 - 0.033 13.8 6.1 0.025 14.2 3.8 1.8 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.13 KNZ74552.1 - 0.15 12.2 2.1 0.32 11.1 0.7 2.0 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein dsrm PF00035.26 KNZ74554.1 - 8e-07 29.7 0.0 1.2e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif RhoGAP PF00620.27 KNZ74555.1 - 1.7e-08 34.5 0.1 8.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KNZ74555.1 - 2.8e-06 27.3 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KNZ74555.1 - 5.9e-05 23.3 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.6 KNZ74555.1 - 7 5.9 9.2 0.92 8.8 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Histone_H2A_C PF16211.5 KNZ74556.1 - 9.7e-15 54.0 0.5 1.5e-14 53.4 0.5 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KNZ74556.1 - 5.4e-10 39.7 0.2 6.6e-10 39.5 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNZ74556.1 - 0.034 14.4 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M50B PF13398.6 KNZ74557.1 - 6.1e-45 153.3 13.8 7e-45 153.1 13.8 1.0 1 0 0 1 1 1 1 Peptidase M50B-like 7tm_3 PF00003.22 KNZ74557.1 - 0.055 13.2 8.8 0.15 11.7 8.8 1.7 1 1 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR Fis1_TPR_C PF14853.6 KNZ74558.1 - 1.5e-23 82.6 0.6 3e-23 81.7 0.6 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KNZ74558.1 - 1.2e-14 53.7 0.0 2.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 KNZ74558.1 - 0.031 14.4 0.3 0.075 13.2 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Gram_pos_anchor PF00746.21 KNZ74558.1 - 0.57 10.2 2.4 0.98 9.4 2.4 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif RRM_1 PF00076.22 KNZ74559.1 - 1.3e-33 114.6 2.3 1.5e-15 56.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ74559.1 - 2.5e-06 27.5 0.0 0.00062 19.8 0.0 2.9 3 1 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 KNZ74559.1 - 0.00072 19.4 0.0 0.72 9.8 0.0 3.2 3 1 0 3 3 3 2 Occluded RNA-recognition motif MTCP1 PF08991.10 KNZ74560.1 - 3.8e-05 23.8 1.6 5.3e-05 23.4 1.6 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KNZ74560.1 - 0.0012 18.9 5.4 0.0017 18.4 5.4 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 KNZ74560.1 - 0.002 18.4 2.1 0.004 17.4 2.1 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Amidase PF01425.21 KNZ74561.1 - 6.7e-101 338.5 0.0 9.7e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 Amidase SLC35F PF06027.12 KNZ74562.1 - 1.4e-100 336.7 17.6 1.7e-100 336.5 17.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KNZ74562.1 - 9.3e-11 41.3 0.2 9.3e-11 41.3 0.2 1.5 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KNZ74562.1 - 0.012 15.7 28.1 0.025 14.8 0.8 3.2 2 1 1 3 3 3 0 EamA-like transporter family Deltameth_res PF16020.5 KNZ74562.1 - 0.032 14.1 2.7 0.11 12.3 0.0 3.2 3 0 0 3 3 3 0 Deltamethrin resistance Zip PF02535.22 KNZ74562.1 - 2.8 7.1 4.8 11 5.1 1.7 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Selenoprotein_S PF06936.11 KNZ74563.1 - 0.056 13.3 1.4 0.077 12.8 1.4 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) SF3b1 PF08920.10 KNZ74564.1 - 1.7e-25 89.8 2.4 1.7e-25 89.8 2.4 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 KNZ74564.1 - 3.2e-09 37.1 9.9 0.012 16.0 0.1 7.5 4 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 KNZ74564.1 - 2.9e-07 30.9 9.0 0.013 16.0 0.0 7.6 9 1 1 10 10 10 1 HEAT-like repeat HEAT PF02985.22 KNZ74564.1 - 3.9e-07 29.8 11.9 0.06 13.6 0.1 9.6 12 0 0 12 12 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KNZ74564.1 - 1.9e-06 28.4 1.4 1.2 9.8 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KNZ74564.1 - 3.9e-06 25.7 1.7 0.041 12.4 0.1 3.3 2 1 0 3 3 3 3 Adaptin N terminal region NUC173 PF08161.12 KNZ74564.1 - 6.4e-05 22.7 0.8 2 8.0 0.0 4.9 4 1 1 5 5 5 2 NUC173 domain Cnd1 PF12717.7 KNZ74564.1 - 0.00027 21.0 8.9 0.53 10.3 0.0 6.4 8 0 0 8 8 8 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 KNZ74564.1 - 0.00056 19.8 0.2 0.8 9.6 0.0 4.7 4 2 2 6 6 6 1 UME (NUC010) domain CLASP_N PF12348.8 KNZ74564.1 - 0.00072 19.2 1.7 1.5 8.3 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal DUF3110 PF11360.8 KNZ74564.1 - 0.016 15.4 0.1 0.047 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Dopey_N PF04118.14 KNZ74564.1 - 0.15 11.1 1.9 4.3 6.4 0.0 3.3 4 0 0 4 4 4 0 Dopey, N-terminal Adaptin_N PF01602.20 KNZ74565.1 - 3.1e-139 464.9 9.3 4e-139 464.5 9.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KNZ74565.1 - 3.1e-21 75.8 0.7 3.1e-21 75.8 0.7 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 KNZ74565.1 - 2.3e-06 27.7 11.7 1.2e-05 25.4 0.4 3.8 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ74565.1 - 0.0019 18.6 2.2 1.7 9.1 0.2 4.2 4 0 0 4 4 4 1 HEAT repeats Microcin PF03526.13 KNZ74565.1 - 0.077 12.8 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein Peptidase_M73 PF12389.8 KNZ74565.1 - 0.08 12.8 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Glyco_hydro_47 PF01532.20 KNZ74566.1 - 2.4e-120 402.5 0.0 1.1e-119 400.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Evr1_Alr PF04777.13 KNZ74567.1 - 3.4e-26 91.6 0.0 5.5e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Zip PF02535.22 KNZ74568.1 - 1.5e-62 211.8 8.9 1.7e-62 211.6 8.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-HIT PF04438.16 KNZ74569.1 - 6.5e-09 35.5 10.0 6.5e-09 35.5 10.0 2.2 3 0 0 3 3 3 1 HIT zinc finger zf-MYND PF01753.18 KNZ74569.1 - 0.05 13.7 8.5 0.12 12.5 7.7 2.0 1 1 1 2 2 2 0 MYND finger PolC_DP2 PF03833.13 KNZ74569.1 - 5 4.9 5.5 6.9 4.4 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DEAD PF00270.29 KNZ74570.1 - 4.6e-37 127.5 0.0 8.6e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ74570.1 - 3.2e-13 50.0 0.0 9.3e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ74570.1 - 0.0043 17.1 0.0 0.013 15.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 KNZ74570.1 - 0.02 13.2 4.3 0.028 12.7 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SWIRM-assoc_2 PF16496.5 KNZ74570.1 - 0.28 10.0 5.3 0.43 9.4 5.3 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Apt1 PF10351.9 KNZ74570.1 - 5.2 5.8 11.8 0.21 10.4 4.8 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Ribosomal_S10 PF00338.22 KNZ74571.1 - 4.2e-28 97.4 0.3 5.1e-28 97.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FGGY_N PF00370.21 KNZ74572.1 - 5.8e-62 209.4 0.1 4.3e-60 203.3 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KNZ74572.1 - 5e-61 205.9 0.9 7.7e-61 205.3 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Glyco_hydro_47 PF01532.20 KNZ74573.1 - 2.2e-128 429.1 0.0 2.6e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pox_G7 PF05503.12 KNZ74573.1 - 0.044 12.7 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like ANTH PF07651.16 KNZ74574.1 - 1.1e-47 162.3 0.0 2.5e-47 161.2 0.0 1.6 1 1 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 KNZ74574.1 - 0.00046 20.5 1.6 0.00046 20.5 1.6 8.0 3 1 2 5 5 5 2 Domain of unknown function (DUF1720) ENTH PF01417.20 KNZ74574.1 - 0.00065 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 ENTH domain SHNi-TPR PF10516.9 KNZ74575.1 - 2.4e-16 58.9 0.2 4.3e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_12 PF13424.6 KNZ74575.1 - 2.1e-14 53.6 1.6 2.2e-06 27.8 0.2 2.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ74575.1 - 7.1e-07 28.8 3.4 0.019 14.7 0.6 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74575.1 - 3.2e-06 27.7 3.3 0.015 16.0 0.5 4.4 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74575.1 - 7.9e-06 25.6 8.3 0.045 13.9 0.6 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ74575.1 - 1.7e-05 24.4 7.2 0.054 13.2 0.9 4.9 4 2 1 5 5 5 2 TPR repeat TPR_7 PF13176.6 KNZ74575.1 - 0.0004 20.2 0.2 1.4 9.1 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ74575.1 - 0.00042 20.3 6.1 0.2 12.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ74575.1 - 0.00072 19.3 0.0 0.38 10.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ74575.1 - 0.0021 18.5 10.8 0.031 14.8 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ74575.1 - 0.04 13.3 0.5 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 MalT-like TPR region MIT PF04212.18 KNZ74575.1 - 0.07 13.2 5.4 0.14 12.2 0.3 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 KNZ74575.1 - 0.23 12.4 9.0 20 6.4 0.1 4.7 4 1 1 5 5 4 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 KNZ74576.1 - 2.2e-40 138.7 15.3 2.5e-40 138.5 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SprA-related PF12118.8 KNZ74576.1 - 0.56 9.3 3.8 0.6 9.2 3.3 1.4 1 1 0 1 1 1 0 SprA-related family Glyco_hydro_28 PF00295.17 KNZ74577.1 - 2.3e-42 145.2 15.6 2.7e-42 145.0 15.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 KNZ74578.1 - 2.8e-40 137.9 6.1 3.8e-40 137.5 6.1 1.0 1 0 0 1 1 1 1 Pectinesterase zf-RING_2 PF13639.6 KNZ74579.1 - 1e-08 35.4 5.6 1e-08 35.4 5.6 4.0 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KNZ74579.1 - 3.5e-08 33.3 4.7 3.5e-08 33.3 4.7 3.9 2 1 1 3 3 3 1 zinc-RING finger domain IBR PF01485.21 KNZ74579.1 - 1.2e-06 28.6 5.6 1.2e-06 28.6 5.6 4.2 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 KNZ74579.1 - 2.2e-06 27.6 3.0 2.2e-06 27.6 3.0 3.8 3 1 0 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 KNZ74579.1 - 6.5e-06 25.9 4.1 6.5e-06 25.9 4.1 4.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ74579.1 - 3.6e-05 23.5 4.9 3.6e-05 23.5 4.9 5.1 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ74579.1 - 0.00046 20.0 3.7 0.00046 20.0 3.7 4.5 2 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KNZ74579.1 - 0.0041 16.8 3.1 0.0041 16.8 3.1 2.9 3 0 0 3 3 3 1 RING-like zinc finger Aldedh PF00171.22 KNZ74580.1 - 4.3e-17 61.8 5.6 1e-12 47.4 3.8 2.6 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 KNZ74580.1 - 0.039 13.4 0.0 0.093 12.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) ATP-synt_ab PF00006.25 KNZ74581.1 - 6.5e-74 248.2 0.0 1.1e-73 247.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KNZ74581.1 - 9e-44 148.8 0.0 1.6e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KNZ74581.1 - 1.7e-17 63.7 1.2 4.1e-17 62.5 1.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AcetDehyd-dimer PF09290.11 KNZ74581.1 - 0.51 10.5 3.6 1.1 9.5 0.6 2.5 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Ribosomal_L21p PF00829.21 KNZ74582.1 - 3e-27 94.8 0.5 3.6e-27 94.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein UvrA_inter PF17760.1 KNZ74582.1 - 0.031 14.4 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 UvrA interaction domain Exo_endo_phos_2 PF14529.6 KNZ74584.1 - 3.7e-08 33.2 0.5 7.1e-08 32.3 0.5 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KNZ74584.1 - 0.00012 21.7 0.3 0.00021 20.9 0.3 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.24 KNZ74585.1 - 4.9e-06 26.8 0.2 9.9e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 RNase H MMS19_C PF12460.8 KNZ74587.1 - 6.4e-104 348.4 3.8 3.4e-102 342.7 0.7 3.3 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 KNZ74587.1 - 4.4e-91 305.1 0.0 5.6e-89 298.2 0.0 3.3 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 KNZ74587.1 - 1.1e-05 25.8 0.5 0.35 11.3 0.0 5.1 5 2 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 KNZ74587.1 - 0.0052 17.3 1.5 0.88 10.1 0.0 4.9 6 0 0 6 6 6 1 HEAT-like repeat CLASP_N PF12348.8 KNZ74587.1 - 0.11 12.0 0.3 2.4 7.7 0.0 3.0 2 1 0 3 3 3 0 CLASP N terminal DUF3385 PF11865.8 KNZ74587.1 - 0.2 11.5 0.9 6.4 6.7 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Methyltransf_28 PF02636.17 KNZ74588.1 - 3.9e-38 131.6 0.0 5.5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 KNZ74588.1 - 0.0077 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 KNZ74588.1 - 0.01 16.6 0.0 0.049 14.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ74588.1 - 0.14 12.9 0.0 0.5 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ74589.1 - 2.3e-12 47.4 0.0 4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ74589.1 - 4.9e-11 43.1 0.0 7.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ74589.1 - 1.7e-09 37.6 0.0 2.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KNZ74589.1 - 0.00092 18.8 0.0 0.0021 17.7 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TPMT PF05724.11 KNZ74589.1 - 0.037 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.18 KNZ74589.1 - 0.15 11.4 0.1 0.61 9.4 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Brix PF04427.18 KNZ74590.1 - 4.7e-21 75.8 0.2 6e-21 75.4 0.2 1.1 1 0 0 1 1 1 1 Brix domain Carn_acyltransf PF00755.20 KNZ74591.1 - 1.9e-170 568.4 0.0 2.2e-170 568.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AATase PF07247.12 KNZ74592.1 - 2.8e-07 29.5 0.0 3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase ZZ PF00569.17 KNZ74593.1 - 1e-16 60.5 56.5 1.4e-06 28.0 6.9 6.2 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.24 KNZ74593.1 - 4.2e-10 39.4 0.5 1.1e-09 38.1 0.1 1.8 2 0 0 2 2 2 1 PB1 domain C1_2 PF03107.16 KNZ74593.1 - 5.6e-06 26.6 46.2 0.13 12.6 2.7 5.7 5 0 0 5 5 5 4 C1 domain FdhE PF04216.12 KNZ74593.1 - 0.64 9.8 0.0 0.64 9.8 0.0 3.7 4 0 0 4 4 4 0 Protein involved in formate dehydrogenase formation PHF5 PF03660.14 KNZ74594.1 - 7.2e-44 148.3 7.9 8.4e-44 148.0 7.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PHD PF00628.29 KNZ74594.1 - 0.49 10.3 10.5 5.1 7.1 10.6 2.4 1 1 1 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 KNZ74594.1 - 1 9.4 9.6 0.12 12.4 3.7 2.2 1 1 1 2 2 2 0 zinc-ribbons C1_2 PF03107.16 KNZ74594.1 - 1.1 9.7 11.8 1.1 9.6 0.4 2.6 1 1 1 2 2 2 0 C1 domain PolC_DP2 PF03833.13 KNZ74594.1 - 1.3 6.8 3.9 1.5 6.6 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C4_ClpX PF06689.13 KNZ74594.1 - 2.6 8.0 11.3 2.5 8.0 0.7 3.1 3 1 0 3 3 3 0 ClpX C4-type zinc finger DZR PF12773.7 KNZ74594.1 - 3.3 7.8 13.5 9.4 6.4 1.0 3.1 1 1 1 2 2 2 0 Double zinc ribbon HECT PF00632.25 KNZ74595.1 - 6.7e-78 262.3 0.0 1.1e-77 261.5 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KNZ74595.1 - 0.024 14.7 1.4 0.87 9.7 0.0 4.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Drf_GBD PF06371.13 KNZ74595.1 - 0.045 13.3 0.1 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain ACOX PF01756.19 KNZ74595.1 - 0.61 9.6 3.6 0.6 9.6 0.1 2.6 3 0 0 3 3 3 0 Acyl-CoA oxidase Aminotran_3 PF00202.21 KNZ74596.1 - 4.1e-68 229.9 0.1 1.4e-41 142.5 0.3 2.0 2 0 0 2 2 2 2 Aminotransferase class-III DRMBL PF07522.14 KNZ74597.1 - 1e-28 99.7 0.0 2.5e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KNZ74597.1 - 2.4e-06 27.2 0.0 4.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KNZ74597.1 - 0.036 14.1 2.9 0.13 12.3 2.9 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Ribosomal_S4e PF00900.20 KNZ74598.1 - 1.1e-35 121.3 0.2 4.4e-35 119.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 KNZ74598.1 - 1.6e-25 88.4 0.2 2.9e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KNZ74598.1 - 1.4e-08 34.7 0.5 2.9e-08 33.7 0.3 1.7 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 KNZ74598.1 - 7.5e-08 32.0 0.0 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KNZ74598.1 - 5.4e-05 23.0 4.3 5.4e-05 23.0 4.3 2.1 2 0 0 2 2 2 1 KOW motif Sipho_tail PF05709.11 KNZ74598.1 - 0.049 13.0 0.0 0.21 11.0 0.0 1.7 1 1 1 2 2 2 0 Phage tail protein IBR PF01485.21 KNZ74599.1 - 6e-08 32.8 5.9 6e-08 32.8 5.9 3.7 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KNZ74599.1 - 1.9e-06 28.1 7.0 1.9e-06 28.1 7.0 3.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 KNZ74599.1 - 6.1e-06 26.1 6.9 6.1e-06 26.1 6.9 3.6 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ74599.1 - 3.7e-05 23.7 4.6 3.7e-05 23.7 4.6 2.9 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNZ74599.1 - 0.00099 18.9 6.8 0.00099 18.9 6.8 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ74599.1 - 0.0025 17.7 7.4 0.0025 17.7 7.4 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ74599.1 - 0.0098 15.7 5.9 0.0098 15.7 5.9 4.1 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KNZ74599.1 - 0.28 10.9 8.9 0.034 13.9 3.6 2.4 2 0 0 2 2 2 0 RING-like zinc finger UIM PF02809.20 KNZ74599.1 - 0.38 10.8 1.8 0.79 9.8 1.8 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif TPT PF03151.16 KNZ74600.1 - 3e-47 161.4 13.9 3.8e-47 161.0 13.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KNZ74600.1 - 1.5e-09 38.1 21.3 0.0002 21.6 12.0 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KNZ74600.1 - 3.4e-08 33.0 14.8 4.5e-08 32.7 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family DUF5317 PF17248.2 KNZ74600.1 - 1.7 8.6 11.9 1.8 8.5 0.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5317) Multi_Drug_Res PF00893.19 KNZ74600.1 - 6.7 7.5 11.9 3 8.6 1.3 3.3 2 1 1 3 3 3 0 Small Multidrug Resistance protein CRAL_TRIO PF00650.20 KNZ74601.1 - 2.1e-25 89.3 0.0 3.4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ74601.1 - 0.0012 19.0 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HIG_1_N PF04588.13 KNZ74601.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Ribosomal_L37ae PF01780.19 KNZ74603.1 - 1.9e-42 143.2 10.1 2.2e-42 143.0 10.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 KNZ74603.1 - 0.00057 20.0 2.5 0.00081 19.5 2.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 KNZ74603.1 - 0.0021 18.0 1.4 0.0034 17.3 1.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1364 PF07102.12 KNZ74603.1 - 0.016 15.1 0.6 0.023 14.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) zf-H2C2_2 PF13465.6 KNZ74603.1 - 0.13 12.8 3.8 2.8 8.5 0.8 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-BED PF02892.15 KNZ74603.1 - 0.27 11.3 4.4 7.7 6.6 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 KNZ74603.1 - 0.29 11.5 2.3 0.71 10.2 2.3 1.6 1 1 0 1 1 1 0 C1 domain Paf1 PF03985.13 KNZ74604.1 - 2.3e-52 178.4 0.1 2.8e-52 178.2 0.1 1.0 1 0 0 1 1 1 1 Paf1 GFO_IDH_MocA PF01408.22 KNZ74605.1 - 2.9e-20 73.3 0.0 4.6e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KNZ74605.1 - 0.038 14.0 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DXP_reductoisom PF02670.16 KNZ74605.1 - 0.064 14.0 0.0 0.25 12.1 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase WD40 PF00400.32 KNZ74606.1 - 0.00026 21.7 0.0 0.25 12.3 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat SET PF00856.28 KNZ74607.1 - 8.1e-10 39.3 0.2 5.6e-09 36.6 0.2 1.9 1 1 0 1 1 1 1 SET domain Complex1_LYR PF05347.15 KNZ74608.1 - 3.9e-06 26.8 1.0 6.7e-06 26.1 1.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) CNH PF00780.22 KNZ74609.1 - 4.3e-75 252.8 0.0 6.6e-75 252.2 0.0 1.3 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KNZ74609.1 - 2.6e-33 115.8 0.0 4.4e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KNZ74609.1 - 2.8e-32 111.6 0.0 5.3e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KNZ74609.1 - 9.1e-12 44.9 0.1 1.8e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KNZ74609.1 - 0.0059 16.4 0.1 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Polysacc_deac_1 PF01522.21 KNZ74610.1 - 5.2e-29 100.7 0.0 8.2e-29 100.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3489 PF11994.8 KNZ74610.1 - 0.16 12.0 0.2 0.43 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Sec1 PF00995.23 KNZ74611.1 - 2.6e-124 416.6 0.0 3.2e-124 416.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Cortex-I_coil PF09304.10 KNZ74611.1 - 1.2 9.4 4.1 22 5.3 0.1 3.0 4 0 0 4 4 4 0 Cortexillin I, coiled coil AAA PF00004.29 KNZ74612.1 - 1.8e-42 144.9 0.0 3.5e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ74612.1 - 3.6e-12 45.9 0.9 1e-11 44.4 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 KNZ74612.1 - 5.9e-08 32.5 1.2 1.2e-07 31.5 0.1 2.2 2 1 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KNZ74612.1 - 1.7e-07 31.4 0.1 1.9e-06 27.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ74612.1 - 5.1e-07 30.2 0.0 0.00024 21.5 0.0 2.8 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 KNZ74612.1 - 8.2e-06 26.0 0.0 2.7e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KNZ74612.1 - 8.6e-06 25.6 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KNZ74612.1 - 0.00023 21.4 0.1 0.0058 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 KNZ74612.1 - 0.00056 19.5 0.0 0.0059 16.1 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 KNZ74612.1 - 0.0013 19.2 0.0 0.0044 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.13 KNZ74612.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KNZ74612.1 - 0.0027 17.1 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 KNZ74612.1 - 0.0035 16.6 0.0 0.0075 15.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain Prot_ATP_OB_N PF17758.1 KNZ74612.1 - 0.0047 16.5 0.1 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 KNZ74612.1 - 0.0051 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 KNZ74612.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KNZ74612.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 KNZ74612.1 - 0.0087 16.2 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KNZ74612.1 - 0.012 15.6 0.0 0.033 14.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 KNZ74612.1 - 0.012 15.3 0.0 0.045 13.5 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 KNZ74612.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNZ74612.1 - 0.018 14.7 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KNZ74612.1 - 0.02 15.1 0.1 0.054 13.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 KNZ74612.1 - 0.022 14.2 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 KNZ74612.1 - 0.033 13.9 0.1 0.088 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain Mnd1 PF03962.15 KNZ74612.1 - 0.039 14.2 0.2 0.098 13.0 0.2 1.7 1 0 0 1 1 1 0 Mnd1 HTH domain AAA_11 PF13086.6 KNZ74612.1 - 0.042 13.6 1.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KNZ74612.1 - 0.047 13.0 0.9 0.19 11.0 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 KNZ74612.1 - 0.058 13.9 2.7 12 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 KNZ74612.1 - 0.065 12.3 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KNZ74612.1 - 0.07 12.4 0.9 0.35 10.1 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KNZ74612.1 - 0.074 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain HBM PF16591.5 KNZ74612.1 - 0.084 12.3 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF4200 PF13863.6 KNZ74612.1 - 0.084 13.3 2.6 0.19 12.1 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) NACHT PF05729.12 KNZ74612.1 - 0.084 12.8 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 1 0 NACHT domain CPT PF07931.12 KNZ74612.1 - 0.15 11.9 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 KNZ74612.1 - 0.17 12.2 0.2 0.44 10.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Peptidase_S10 PF00450.22 KNZ74613.1 - 2.9e-61 208.2 0.1 7.3e-61 206.8 0.1 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase GCFC PF07842.12 KNZ74614.1 - 1.9e-78 263.9 7.9 2.2e-78 263.7 7.2 1.4 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 KNZ74614.1 - 5.3e-13 49.2 21.3 5.3e-13 49.2 21.3 3.2 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch PF01585.23 KNZ74614.1 - 2.3e-12 46.6 1.3 5.5e-12 45.4 1.3 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KNZ74614.1 - 5e-08 32.9 0.7 1.8e-06 27.9 0.3 2.8 2 0 0 2 2 2 1 G-patch domain DUF3333 PF11812.8 KNZ74614.1 - 0.2 11.9 0.1 0.2 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Sof1 PF04158.14 KNZ74616.1 - 1.6e-28 98.8 11.6 1.6e-28 98.8 11.6 2.0 3 0 0 3 3 3 1 Sof1-like domain WD40 PF00400.32 KNZ74616.1 - 3.3e-25 87.9 9.3 2.4e-08 34.5 0.5 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ74616.1 - 1.1e-07 32.0 0.1 0.5 10.7 0.0 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ74616.1 - 0.012 15.5 0.0 0.31 10.9 0.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KNZ74617.1 - 3.1e-13 50.0 1.3 0.012 16.5 0.0 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ74617.1 - 0.0075 16.6 0.0 1.6 9.1 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ74617.1 - 0.053 13.5 0.0 3.2 7.8 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FGGY_N PF00370.21 KNZ74618.1 - 1.7e-25 90.0 0.0 1.6e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 KNZ74618.1 - 5e-14 52.5 0.0 9.1e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain PseudoU_synth_1 PF01416.20 KNZ74618.1 - 5.9e-13 49.2 0.0 3.5e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase RNA_pol_Rpb4 PF03874.16 KNZ74619.1 - 3.6e-19 69.3 0.9 4.5e-19 69.0 0.9 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 Stm1_N PF09598.10 KNZ74621.1 - 0.05 14.5 2.1 0.093 13.6 2.1 1.4 1 0 0 1 1 1 0 Stm1 Aa_trans PF01490.18 KNZ74622.1 - 1.5e-67 228.1 24.8 2.5e-62 210.9 18.5 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CDC27 PF09507.10 KNZ74622.1 - 2e-36 126.4 59.8 1.3e-35 123.6 59.8 2.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Fungal_trans PF04082.18 KNZ74623.1 - 0.046 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF202 PF02656.15 KNZ74624.1 - 0.00056 20.3 2.7 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CopD PF05425.13 KNZ74624.1 - 0.005 17.2 1.3 0.052 14.0 0.0 2.1 2 0 0 2 2 2 1 Copper resistance protein D MTHFR PF02219.17 KNZ74625.1 - 1.5e-105 352.7 0.0 2.3e-105 352.1 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PH_12 PF16457.5 KNZ74626.1 - 9.5e-36 123.3 0.0 1.8e-35 122.4 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KNZ74626.1 - 8.7e-28 97.2 0.0 3.1e-27 95.4 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) ELMO_CED12 PF04727.13 KNZ74626.1 - 1.2e-26 93.9 0.1 1.9e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family V-ATPase_H_C PF11698.8 KNZ74626.1 - 0.011 15.9 0.3 1.5 9.0 0.0 2.7 2 0 0 2 2 2 0 V-ATPase subunit H Tristanin_u2 PF16638.5 KNZ74626.1 - 0.067 14.0 0.2 0.22 12.4 0.1 1.9 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers RCC1 PF00415.18 KNZ74628.1 - 3.6e-15 56.3 3.9 0.0009 19.8 0.0 6.9 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNZ74628.1 - 1.3e-12 47.2 19.3 3.2e-06 26.8 0.7 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat FOXP-CC PF16159.5 KNZ74629.1 - 0.014 16.0 0.4 0.03 14.9 0.4 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 KNZ74629.1 - 0.039 14.4 0.4 0.12 12.9 0.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C3HC4 PF00097.25 KNZ74630.1 - 1.8e-05 24.5 13.2 3.7e-05 23.5 13.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ74630.1 - 0.00025 20.8 15.7 0.0081 16.0 15.7 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KNZ74630.1 - 0.00064 19.5 4.5 0.0014 18.5 4.5 1.6 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 KNZ74630.1 - 0.0013 18.7 9.7 0.0013 18.7 9.7 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KNZ74630.1 - 0.0017 18.7 15.9 0.0076 16.6 15.9 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KNZ74630.1 - 0.002 18.2 10.7 0.023 14.8 11.1 2.4 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KNZ74630.1 - 0.0024 18.0 9.0 0.0064 16.6 8.6 2.0 1 1 0 1 1 1 1 zinc RING finger of MSL2 Baculo_IE-1 PF05290.11 KNZ74630.1 - 0.0085 16.1 1.2 0.014 15.3 1.2 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Tmpp129 PF10272.9 KNZ74630.1 - 0.01 15.2 5.4 0.015 14.6 5.4 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_5 PF14634.6 KNZ74630.1 - 0.03 14.3 11.9 0.058 13.4 11.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain CENP-Q PF13094.6 KNZ74630.1 - 0.42 10.8 8.4 0.31 11.2 3.5 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-rbx1 PF12678.7 KNZ74630.1 - 0.52 10.6 16.2 3.9 7.8 16.2 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KNZ74630.1 - 0.99 9.5 9.2 2.8 8.1 9.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KNZ74630.1 - 1.8 8.4 8.1 6 6.7 8.1 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Actin PF00022.19 KNZ74631.1 - 1.5e-23 83.1 0.0 4.1e-13 48.7 0.0 3.0 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KNZ74631.1 - 1e-09 38.1 0.2 1e-06 28.2 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KNZ74631.1 - 3.5e-05 22.8 0.1 7.5e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KNZ74631.1 - 0.095 13.1 0.4 0.2 12.1 0.4 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Peptidase_M20 PF01546.28 KNZ74633.1 - 2.4e-33 115.6 0.0 4.7e-33 114.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KNZ74633.1 - 4e-11 42.8 0.0 7.1e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KNZ74633.1 - 0.0014 18.3 0.0 0.0033 17.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 V-ATPase_G PF03179.15 KNZ74634.1 - 2.8e-34 117.8 14.3 3.5e-34 117.5 14.3 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 KNZ74634.1 - 0.48 9.8 16.9 0.19 11.1 9.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 KNZ74634.1 - 0.49 10.5 20.0 0.077 13.1 14.7 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 KNZ74634.1 - 0.7 10.3 18.8 2.7 8.4 14.4 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Fungal_trans PF04082.18 KNZ74635.1 - 6.8e-19 67.9 1.8 1e-18 67.3 1.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_60s PF00428.19 KNZ74635.1 - 3.2e-16 59.7 8.8 6.3e-16 58.7 8.8 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Zn_clus PF00172.18 KNZ74635.1 - 2.8e-09 36.9 9.3 5.1e-09 36.1 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S19 PF00203.21 KNZ74636.1 - 6.9e-32 109.2 0.2 1.1e-31 108.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.16 KNZ74636.1 - 0.0032 17.5 0.0 0.0044 17.1 0.0 1.2 1 0 0 1 1 1 1 Flagellar assembly protein FliH Symplekin_C PF12295.8 KNZ74637.1 - 3.5e-64 216.4 2.8 2.6e-63 213.5 0.3 3.0 3 0 0 3 3 3 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 KNZ74637.1 - 4.2e-52 177.0 1.8 1.2e-51 175.6 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HEAT_EZ PF13513.6 KNZ74637.1 - 0.02 15.4 1.9 46 4.7 0.0 5.0 6 0 0 6 6 6 0 HEAT-like repeat HEAT_2 PF13646.6 KNZ74637.1 - 0.043 14.2 0.5 4.5 7.7 0.0 3.6 4 0 0 4 4 4 0 HEAT repeats Pkinase PF00069.25 KNZ74638.1 - 1.6e-53 181.8 0.0 7.6e-43 146.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74638.1 - 7.2e-26 91.0 0.0 1.4e-18 67.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ74638.1 - 0.0013 18.7 2.4 0.13 12.2 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ74638.1 - 0.055 12.4 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KNZ74638.1 - 0.092 12.3 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase ParA PF10609.9 KNZ74639.1 - 1.2e-95 319.7 0.0 1.4e-95 319.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KNZ74639.1 - 3.7e-09 36.7 0.0 1.1e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 KNZ74639.1 - 1.1e-05 24.8 1.8 0.0017 17.6 0.1 2.8 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 KNZ74639.1 - 7.3e-05 22.7 0.1 0.00054 19.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KNZ74639.1 - 0.0034 16.9 0.1 0.013 15.0 0.1 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 KNZ74639.1 - 0.0085 15.6 0.0 0.68 9.3 0.0 2.4 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 KNZ74639.1 - 0.019 14.8 0.1 0.046 13.6 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 KNZ74639.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 KNZ74639.1 - 0.03 14.1 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KNZ74639.1 - 0.068 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KNZ74639.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 KNZ74639.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E RhoGAP PF00620.27 KNZ74640.1 - 3.8e-34 117.7 0.0 7.4e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KNZ74640.1 - 1.9e-26 92.1 36.9 1.2e-10 41.5 7.9 4.6 4 0 0 4 4 4 4 LIM domain Forkhead PF00250.18 KNZ74641.1 - 6.4e-26 90.4 0.0 1.2e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Arteri_nucleo PF01481.16 KNZ74641.1 - 0.52 10.6 2.2 11 6.4 0.1 2.5 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein Carboxyl_trans PF01039.22 KNZ74642.1 - 2.4e-47 161.7 0.0 3.3e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain DUF4020 PF13212.6 KNZ74642.1 - 0.082 12.7 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) DNA_ligase_A_M PF01068.21 KNZ74643.1 - 1.7e-52 178.1 0.0 2.8e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KNZ74643.1 - 1.8e-41 142.4 0.5 8.6e-41 140.1 0.0 2.5 3 0 0 3 3 3 1 DNA ligase N terminus BRCT_2 PF16589.5 KNZ74643.1 - 1.3e-21 76.8 0.1 1.6e-09 38.0 0.1 3.0 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 KNZ74643.1 - 2.1e-14 53.9 0.3 8.8e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KNZ74643.1 - 1.3e-11 45.1 0.2 4.6e-11 43.3 0.1 2.1 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 KNZ74643.1 - 1.4e-08 35.0 2.0 0.00097 19.5 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KNZ74643.1 - 0.012 15.5 0.0 2.9 7.9 0.0 3.1 3 0 0 3 3 3 0 twin BRCT domain Pkinase PF00069.25 KNZ74644.1 - 4.4e-63 213.1 0.0 7.2e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74644.1 - 7.5e-35 120.4 0.0 1.3e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ74644.1 - 5.5e-06 25.6 1.3 1.2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Fungal_KA1 PF16797.5 KNZ74644.1 - 5.7e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 KNZ74644.1 - 0.00021 20.7 0.0 0.00043 19.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ74644.1 - 0.0043 16.4 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dynein_light PF01221.18 KNZ74645.1 - 2.1e-27 95.3 0.1 2.6e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 He_PIG PF05345.12 KNZ74646.1 - 8e-06 26.0 7.4 0.0005 20.2 3.6 4.0 4 0 0 4 4 4 2 Putative Ig domain HEAT_2 PF13646.6 KNZ74647.1 - 7.4e-13 48.7 3.1 0.028 14.8 0.7 5.5 4 2 0 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 KNZ74647.1 - 2.2e-11 44.0 13.7 0.002 18.6 0.0 7.3 7 1 1 8 8 7 4 HEAT-like repeat HEAT PF02985.22 KNZ74647.1 - 5e-11 41.9 11.4 0.017 15.3 0.0 7.9 9 0 0 9 9 9 3 HEAT repeat IBN_N PF03810.19 KNZ74647.1 - 1.9e-09 37.3 1.4 8.4e-09 35.2 0.2 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 KNZ74647.1 - 0.00013 22.5 0.0 0.29 11.7 0.0 3.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KNZ74647.1 - 0.00027 21.0 0.1 1.2 9.1 0.0 3.8 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KNZ74647.1 - 0.0014 18.6 0.1 0.4 10.6 0.0 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) IFRD PF05004.13 KNZ74647.1 - 0.0017 17.6 0.6 0.12 11.5 0.0 3.4 4 0 0 4 4 4 1 Interferon-related developmental regulator (IFRD) GRIP PF01465.20 KNZ74647.1 - 0.014 15.3 0.0 6.1 6.8 0.0 3.7 3 1 0 3 3 3 0 GRIP domain RIX1 PF08167.12 KNZ74647.1 - 0.082 12.6 1.0 0.76 9.5 0.0 2.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 KNZ74647.1 - 0.14 10.7 0.1 9.4 4.7 0.0 3.6 3 2 2 5 5 5 0 Adaptin N terminal region DHO_dh PF01180.21 KNZ74648.1 - 2.9e-95 318.9 0.0 3.5e-95 318.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 KNZ74648.1 - 0.0081 15.2 0.0 0.053 12.5 0.0 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase MamL-1 PF09596.10 KNZ74648.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 MamL-1 domain BTB PF00651.31 KNZ74649.1 - 3.2e-05 24.1 0.0 7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AIP3 PF03915.13 KNZ74650.1 - 2.1e-142 475.1 8.3 3.1e-142 474.5 8.3 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 ISG65-75 PF11727.8 KNZ74650.1 - 0.0015 17.8 0.9 0.0015 17.8 0.9 1.7 2 0 0 2 2 2 1 Invariant surface glycoprotein DUF1720 PF08226.11 KNZ74650.1 - 0.015 15.7 6.9 0.015 15.7 6.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) OmpH PF03938.14 KNZ74650.1 - 2.8 8.3 15.5 4.8 7.5 0.7 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Metallophos PF00149.28 KNZ74651.1 - 1.9e-13 51.4 0.1 4.9e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ74651.1 - 0.00025 21.3 0.1 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.20 KNZ74652.1 - 6.6e-08 32.8 0.3 1.9e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 LRR_8 PF13855.6 KNZ74653.1 - 9.4e-15 54.1 11.5 1.2e-08 34.6 4.8 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KNZ74653.1 - 8.3e-09 35.6 5.1 2.5e-05 24.5 4.8 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNZ74653.1 - 0.64 10.8 8.6 2.3 9.1 0.2 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat zf-H2C2_2 PF13465.6 KNZ74654.1 - 1.8e-18 66.0 29.6 8e-07 29.2 0.4 5.6 7 0 0 7 7 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ74654.1 - 1.3e-14 53.6 29.1 0.00061 20.4 1.5 7.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ74654.1 - 4.7e-13 48.8 42.9 0.00067 20.0 1.8 7.3 8 1 0 8 8 7 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KNZ74654.1 - 3.7e-07 30.3 7.5 0.11 12.8 0.3 5.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KNZ74654.1 - 0.00019 22.0 28.6 0.022 15.4 0.2 6.7 5 1 2 7 7 6 2 FOXP coiled-coil domain zf_ZIC PF18366.1 KNZ74654.1 - 0.00077 19.5 15.7 0.046 13.8 0.0 5.7 6 2 1 7 7 7 2 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 KNZ74654.1 - 0.0039 17.5 13.9 0.55 10.6 4.3 4.4 4 1 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KNZ74654.1 - 0.0058 16.4 24.5 0.0081 15.9 0.3 6.3 6 1 0 6 6 6 1 zinc-finger C2H2-type zf-met PF12874.7 KNZ74654.1 - 0.0064 16.9 15.2 0.28 11.7 1.5 5.4 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 KNZ74654.1 - 0.017 14.7 4.0 0.72 9.5 0.3 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2_9 PF16293.5 KNZ74654.1 - 0.51 10.2 6.4 36 4.3 0.1 4.1 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-MYST PF17772.1 KNZ74654.1 - 0.54 9.9 7.1 0.12 12.1 0.7 2.7 2 1 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 KNZ74654.1 - 0.68 10.0 20.3 6.7 6.8 1.7 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger Cytochrom_CIII PF02085.16 KNZ74654.1 - 1.9 8.9 11.7 4.4 7.7 11.7 1.6 1 0 0 1 1 1 0 Class III cytochrome C family zf-Di19 PF05605.12 KNZ74654.1 - 3 8.2 23.1 6 7.3 0.6 5.0 4 1 1 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 KNZ74654.1 - 3.8 7.5 11.1 7.9 6.5 0.0 4.3 5 0 0 5 5 5 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 KNZ74654.1 - 9.5 6.2 7.6 3.9 7.5 0.1 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain CTP_transf_like PF01467.26 KNZ74655.1 - 8.8e-15 55.1 0.0 2.7e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like CUE PF02845.16 KNZ74656.1 - 0.04 13.6 0.1 0.19 11.5 0.0 2.3 2 1 0 2 2 2 0 CUE domain FAD_binding_3 PF01494.19 KNZ74657.1 - 5.8e-50 170.5 0.0 4.3e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Tma16 PF11176.8 KNZ74658.1 - 1.2e-44 151.7 3.9 1.4e-44 151.5 3.9 1.0 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MOZART1 PF12554.8 KNZ74659.1 - 4.6e-18 64.7 0.2 5.4e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Zds_C PF08632.10 KNZ74660.1 - 3e-28 97.3 1.0 5.4e-28 96.5 1.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF4337 PF14235.6 KNZ74660.1 - 1.5 9.0 3.4 3 7.9 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Presenilin PF01080.17 KNZ74660.1 - 5.5 5.6 5.3 14 4.3 5.3 1.6 1 0 0 1 1 1 0 Presenilin ACC_central PF08326.12 KNZ74661.1 - 5.4e-238 791.9 0.0 7.3e-238 791.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KNZ74661.1 - 6.5e-170 566.0 0.0 8.5e-170 565.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain P34-Arc PF04045.14 KNZ74661.1 - 5.3e-108 360.3 0.1 9.3e-108 359.5 0.1 1.4 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc CPSase_L_D2 PF02786.17 KNZ74661.1 - 3.7e-52 176.9 0.1 9e-52 175.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KNZ74661.1 - 1.8e-28 99.3 0.1 4e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KNZ74661.1 - 2.2e-21 76.0 0.0 2.2e-20 72.8 0.0 2.7 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KNZ74661.1 - 1.6e-16 59.9 0.2 4.7e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KNZ74661.1 - 0.001 18.7 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KNZ74661.1 - 0.0017 18.4 0.0 0.0053 16.8 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.21 KNZ74662.1 - 3.6e-17 62.7 0.3 1.2e-16 60.9 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ74662.1 - 4.2e-16 58.8 0.0 1.2e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ74662.1 - 2.3e-11 43.9 0.0 3.1e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KNZ74662.1 - 2.3e-10 40.1 0.0 2.8e-08 33.2 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 KNZ74662.1 - 3.7e-09 36.5 0.1 2.6e-07 30.4 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 KNZ74662.1 - 1.2e-06 28.2 0.2 1.2e-06 28.2 0.2 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KNZ74662.1 - 0.034 13.3 0.0 0.85 8.7 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein BtpA PF03437.15 KNZ74662.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 BtpA family APH PF01636.23 KNZ74663.1 - 1e-10 42.0 0.0 1.7e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family rve PF00665.26 KNZ74665.1 - 0.02 15.1 0.0 0.027 14.7 0.0 1.1 1 0 0 1 1 1 0 Integrase core domain F-box-like PF12937.7 KNZ74667.1 - 1e-06 28.5 2.3 9.7e-06 25.4 0.2 3.1 3 0 0 3 3 3 1 F-box-like UPF0444 PF15475.6 KNZ74667.1 - 0.065 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 F-box PF00646.33 KNZ74667.1 - 5.9 6.9 10.6 6.8 6.7 5.4 3.3 2 1 0 2 2 2 0 F-box domain RVP_2 PF08284.11 KNZ74668.1 - 0.019 14.7 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease DoxX_3 PF13781.6 KNZ74668.1 - 0.072 13.7 0.0 0.078 13.6 0.0 1.1 1 0 0 1 1 1 0 DoxX-like family Helitron_like_N PF14214.6 KNZ74670.1 - 7.1e-10 39.4 0.0 7.7e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ74671.1 - 2e-22 79.9 0.0 2.4e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74671.1 - 1.7e-11 44.2 0.0 2.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ74671.1 - 2.6e-08 34.3 0.0 6.6e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ74671.1 - 0.00012 22.1 0.1 0.00016 21.7 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 KNZ74671.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.18 KNZ74671.1 - 0.0091 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 KNZ74671.1 - 0.025 14.6 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 KNZ74671.1 - 0.059 13.8 0.0 0.098 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ74671.1 - 0.09 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KNZ74671.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein HAMP PF00672.25 KNZ74672.1 - 0.019 15.3 0.0 0.058 13.8 0.0 1.8 2 0 0 2 2 2 0 HAMP domain DUF1882 PF08966.11 KNZ74672.1 - 0.03 14.6 0.1 0.05 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) UPF0547 PF10571.9 KNZ74672.1 - 0.078 13.1 0.4 0.16 12.1 0.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 APH PF01636.23 KNZ74673.1 - 0.0004 20.4 0.0 0.00077 19.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KNZ74673.1 - 0.091 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.23 KNZ74674.1 - 0.027 14.4 0.0 0.078 12.9 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF5320 PF17253.2 KNZ74675.1 - 0.038 15.1 5.9 0.065 14.3 5.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FoP_duplication PF13865.6 KNZ74675.1 - 0.36 11.4 9.9 0.61 10.7 9.9 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tannase PF07519.11 KNZ74678.1 - 8.3e-97 325.0 0.0 1e-96 324.7 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KNZ74678.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MAD PF05557.13 KNZ74680.1 - 1.9e-36 125.7 55.2 1e-29 103.5 10.5 2.7 1 1 1 2 2 2 2 Mitotic checkpoint protein MT0933_antitox PF14013.6 KNZ74681.1 - 0.0076 16.5 0.4 0.044 14.1 0.2 2.1 1 1 1 2 2 2 1 MT0933-like antitoxin protein LRR_4 PF12799.7 KNZ74682.1 - 4.5e-06 26.9 4.6 0.1 13.1 0.2 5.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) Methyltransf_16 PF10294.9 KNZ74684.1 - 6.1e-14 52.1 0.0 8.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KNZ74684.1 - 0.029 13.8 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GTP_EFTU PF00009.27 KNZ74688.1 - 1.7e-50 171.2 0.0 2.6e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KNZ74688.1 - 7.3e-15 54.8 0.5 1.8e-14 53.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 KNZ74688.1 - 8e-05 22.7 0.0 0.00031 20.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KNZ74688.1 - 0.00017 21.9 4.7 0.0043 17.4 0.6 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KNZ74688.1 - 0.018 15.1 0.0 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Elongation Factor G, domain II AAA_19 PF13245.6 KNZ74688.1 - 0.055 13.8 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 KNZ74688.1 - 0.19 11.2 0.1 9.7 5.6 0.1 2.3 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit ANAPC4_WD40 PF12894.7 KNZ74690.1 - 0.00012 22.3 0.0 0.38 11.1 0.0 4.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 KNZ74690.1 - 0.00037 20.3 0.3 0.025 14.3 0.0 3.1 4 0 0 4 4 4 1 TUP1-like enhancer of split AAA_16 PF13191.6 KNZ74691.1 - 1.7e-10 41.6 0.2 6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KNZ74691.1 - 2.1e-08 34.2 0.0 4.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 KNZ74691.1 - 4.4e-06 27.2 0.3 2.6e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ74691.1 - 6.9e-05 23.1 0.1 0.00041 20.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain ATPase_2 PF01637.18 KNZ74691.1 - 8.6e-05 22.6 0.1 0.00023 21.1 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KNZ74691.1 - 0.00026 21.6 0.1 0.0045 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KNZ74691.1 - 0.00029 20.5 0.3 0.0026 17.4 0.3 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KNZ74691.1 - 0.0036 16.6 0.2 0.92 8.8 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin KAP_NTPase PF07693.14 KNZ74691.1 - 0.0071 15.6 3.5 0.12 11.5 0.3 2.7 2 1 1 3 3 3 1 KAP family P-loop domain RNA_helicase PF00910.22 KNZ74691.1 - 0.017 15.5 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KNZ74691.1 - 0.042 13.8 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 KNZ74691.1 - 0.06 12.8 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DSPc PF00782.20 KNZ74692.1 - 1.4e-05 25.0 0.0 2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ74692.1 - 0.018 14.6 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 KNZ74692.1 - 0.083 12.6 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 KNZ74692.1 - 0.2 11.6 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like PF12937.7 KNZ74693.1 - 1.5e-08 34.4 1.0 3.4e-08 33.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ74693.1 - 0.063 13.2 1.2 14 5.7 0.1 2.8 2 0 0 2 2 2 0 F-box domain Peptidase_C14 PF00656.22 KNZ74695.1 - 1.2e-39 136.8 0.0 1.9e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Pkinase_Tyr PF07714.17 KNZ74696.1 - 9.5e-19 67.7 0.0 1.1e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74696.1 - 2.6e-17 63.1 0.0 3.3e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KNZ74696.1 - 0.00066 19.1 0.0 0.00097 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PBP PF01161.20 KNZ74697.1 - 5.3e-19 68.8 0.0 6.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TPR_10 PF13374.6 KNZ74700.1 - 1.6e-258 828.9 56.7 1.6e-15 56.4 0.1 20.2 20 0 0 20 20 20 19 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ74700.1 - 5.7e-251 811.6 97.6 1.4e-18 66.9 0.2 16.4 1 1 16 18 18 18 18 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74700.1 - 6.5e-45 147.7 29.5 0.03 14.4 0.0 18.9 19 0 0 19 19 18 11 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ74700.1 - 4.5e-41 136.3 28.3 0.052 13.9 0.0 18.2 19 0 0 19 19 19 12 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ74700.1 - 3e-40 134.4 30.8 0.036 13.9 0.0 18.8 19 0 0 19 19 19 9 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ74700.1 - 8.6e-39 128.5 30.9 0.076 13.3 0.0 18.7 19 0 0 19 19 19 10 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ74700.1 - 9.9e-36 119.2 42.4 0.12 12.5 0.0 18.2 18 0 0 18 18 18 11 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ74700.1 - 3e-30 105.7 72.6 3.3e-06 26.7 9.2 9.1 1 1 10 11 11 11 11 MalT-like TPR region TPR_16 PF13432.6 KNZ74700.1 - 1.1e-24 86.7 13.5 0.41 11.3 0.0 14.6 6 5 8 14 14 14 8 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ74700.1 - 6.2e-15 54.2 0.0 35 5.4 0.0 13.8 15 0 0 15 15 13 0 Tetratricopeptide repeat nec1 PF10379.9 KNZ74700.1 - 2.6e-13 49.9 3.9 7.8 6.0 0.0 11.9 3 1 10 15 15 15 1 Virulence protein nec1 PPR PF01535.20 KNZ74700.1 - 5.8e-13 48.2 9.7 26 5.3 0.0 15.5 17 0 0 17 17 16 0 PPR repeat Patatin PF01734.22 KNZ74700.1 - 2.6e-08 34.3 0.0 8.2e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 KNZ74700.1 - 2.6e-08 33.4 0.0 1.2e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain RPM2 PF08579.11 KNZ74700.1 - 0.00044 20.6 9.7 27 5.2 0.0 8.5 2 2 7 11 11 11 0 Mitochondrial ribonuclease P subunit (RPM2) ATPase_2 PF01637.18 KNZ74700.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea YlmH_RBD PF17774.1 KNZ74700.1 - 0.0041 17.4 16.0 13 6.2 0.1 8.4 6 1 4 10 10 10 0 Putative RNA-binding domain in YlmH Get5_bdg PF16843.5 KNZ74700.1 - 0.0092 15.5 0.1 39 3.9 0.0 6.3 8 0 0 8 8 7 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein PPR_1 PF12854.7 KNZ74700.1 - 0.013 15.2 29.3 3.6 7.4 0.0 12.7 16 0 0 16 16 16 0 PPR repeat NACHT PF05729.12 KNZ74700.1 - 0.039 13.9 0.4 0.56 10.1 0.0 3.1 4 0 0 4 4 3 0 NACHT domain TPR_19 PF14559.6 KNZ74700.1 - 0.11 13.0 67.2 1.2 9.7 2.0 12.2 6 5 8 15 15 14 0 Tetratricopeptide repeat Pkinase PF00069.25 KNZ74702.1 - 7.6e-61 205.8 0.0 9.5e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74702.1 - 9.6e-27 93.9 0.0 1.2e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ74702.1 - 1.7e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ74702.1 - 0.018 15.0 0.9 0.04 13.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ74702.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KNZ74702.1 - 0.17 10.9 0.1 0.25 10.3 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_10 PF13374.6 KNZ74705.1 - 6.8e-280 896.9 43.9 4.4e-15 55.0 0.1 20.3 20 0 0 20 20 20 20 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ74705.1 - 1.5e-268 867.9 87.2 3.1e-20 72.2 0.3 18.1 1 1 18 19 19 19 19 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ74705.1 - 2.3e-57 187.3 2.8 0.047 14.1 0.0 20.3 20 0 0 20 20 20 16 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74705.1 - 2e-42 139.9 15.4 0.7 10.2 0.2 20.3 20 0 0 20 20 20 10 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ74705.1 - 7.2e-36 120.6 17.7 1.2 9.1 0.1 20.0 20 0 0 20 20 20 8 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ74705.1 - 1.9e-35 118.3 40.5 0.21 11.7 0.1 19.6 19 0 0 19 19 19 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ74705.1 - 6.5e-34 117.8 92.2 6.3e-05 22.5 8.2 10.7 1 1 13 14 14 14 14 MalT-like TPR region TPR_8 PF13181.6 KNZ74705.1 - 2.4e-27 92.8 21.0 4.1 7.9 0.0 19.9 20 0 0 20 20 20 4 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ74705.1 - 1.7e-19 68.3 0.0 93 4.1 0.0 17.0 18 0 0 18 18 18 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74705.1 - 8.2e-14 52.0 11.7 2.7 8.7 0.0 15.0 8 7 7 15 15 15 1 Tetratricopeptide repeat Patatin PF01734.22 KNZ74705.1 - 4.1e-13 50.0 0.0 9.4e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PPR PF01535.20 KNZ74705.1 - 4.5e-06 26.5 7.1 7.1e+02 0.9 0.0 13.6 18 0 0 18 18 18 0 PPR repeat ATPase_2 PF01637.18 KNZ74705.1 - 0.00074 19.5 0.0 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Glyco_hydro_108 PF05838.12 KNZ74705.1 - 0.057 13.9 0.2 1.8e+02 2.7 0.0 5.5 4 2 0 4 4 3 0 Glycosyl hydrolase 108 DUF934 PF06073.12 KNZ74705.1 - 3 7.8 11.1 48 3.9 0.0 7.0 6 4 7 13 13 13 0 Bacterial protein of unknown function (DUF934) U3_snoRNA_assoc PF08297.11 KNZ74706.1 - 0.012 16.3 2.2 0.012 16.3 2.2 2.8 2 2 0 2 2 2 0 U3 snoRNA associated Nop25 PF09805.9 KNZ74706.1 - 0.012 16.1 10.5 0.012 16.1 10.5 2.0 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 KNZ74706.1 - 0.051 12.9 24.1 0.023 14.0 22.1 1.4 1 1 0 1 1 1 0 BUD22 DUF2064 PF09837.9 KNZ74706.1 - 0.055 13.3 1.2 0.11 12.3 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) IKKbetaNEMObind PF12179.8 KNZ74706.1 - 0.096 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain p450 PF00067.22 KNZ74707.1 - 3.9e-69 233.6 0.0 9.3e-69 232.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KNZ74708.1 - 6.8e-58 196.1 0.0 4.3e-31 108.3 0.0 3.9 4 0 0 4 4 4 3 Protein kinase domain HGTP_anticodon2 PF12745.7 KNZ74708.1 - 2.7e-47 161.5 0.2 1.2e-46 159.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 KNZ74708.1 - 3e-30 105.4 0.0 2.9e-15 56.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.6 KNZ74708.1 - 5.9e-08 32.3 0.0 5.9e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.23 KNZ74708.1 - 0.004 17.1 2.7 0.0085 16.0 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RWD PF05773.22 KNZ74708.1 - 0.025 14.9 0.2 0.095 13.0 0.1 2.1 2 0 0 2 2 2 0 RWD domain Pkinase_fungal PF17667.1 KNZ74708.1 - 0.07 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Methyltransf_16 PF10294.9 KNZ74709.1 - 3e-20 72.7 0.0 4.8e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KNZ74709.1 - 0.00044 20.9 0.0 0.00087 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ74709.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ74709.1 - 0.013 16.2 0.0 0.024 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KNZ74709.1 - 0.23 11.2 0.0 0.49 10.1 0.0 1.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1978 PF09321.10 KNZ74710.1 - 0.22 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) Epimerase PF01370.21 KNZ74711.1 - 0.00019 21.0 0.3 0.0017 17.9 0.3 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KNZ74711.1 - 0.00052 19.3 0.0 0.0007 18.8 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KNZ74711.1 - 0.0077 16.1 1.6 0.028 14.3 0.2 2.5 3 1 0 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 KNZ74712.1 - 9.3e-13 48.2 0.1 1.2e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ74712.1 - 3e-11 42.9 0.0 4.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ74712.1 - 2.4e-07 30.8 0.9 9.5e-07 28.9 0.1 2.2 3 0 0 3 3 3 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KNZ74712.1 - 1.2e-06 27.9 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KNZ74712.1 - 0.0007 19.1 0.1 0.0023 17.4 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KNZ74712.1 - 0.0036 16.5 0.1 0.0054 15.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DND1_DSRM PF14709.7 KNZ74712.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 adh_short PF00106.25 KNZ74712.1 - 0.17 11.3 3.6 0.26 10.7 0.3 2.5 2 1 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.21 KNZ74713.1 - 9.1e-11 41.7 0.1 1.8e-09 37.4 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ74713.1 - 1.8e-09 37.0 0.2 7.7e-09 34.9 0.2 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ74713.1 - 5.6e-09 36.1 0.3 1.3e-08 34.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KNZ74713.1 - 2.1e-05 24.2 0.1 3.4e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Cytochrom_D1 PF02239.16 KNZ74713.1 - 0.0053 15.3 0.0 0.014 13.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome D1 heme domain GDP_Man_Dehyd PF16363.5 KNZ74713.1 - 0.012 15.0 0.1 0.042 13.2 0.1 2.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Pardaxin PF07425.11 KNZ74713.1 - 0.4 10.3 2.3 1 9.1 2.3 1.7 1 0 0 1 1 1 0 Pardaxin Cohesin_load PF10345.9 KNZ74714.1 - 0.087 11.3 0.6 1.1 7.6 0.0 2.6 3 1 0 3 3 3 0 Cohesin loading factor VGCC_beta4Aa_N PF12052.8 KNZ74714.1 - 0.37 10.9 1.7 0.98 9.6 1.7 1.7 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Epimerase PF01370.21 KNZ74715.1 - 4.6e-12 45.9 0.0 9e-12 45.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ74715.1 - 9.4e-06 24.8 0.0 1.7e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ74715.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KNZ74715.1 - 0.0022 17.2 0.0 0.0048 16.1 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KNZ74715.1 - 0.0038 16.7 0.1 0.1 11.9 0.0 2.9 4 0 0 4 4 4 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KNZ74715.1 - 0.053 13.1 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 4HBT PF03061.22 KNZ74716.1 - 1.4e-09 38.2 0.1 2.1e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Pkinase_Tyr PF07714.17 KNZ74717.1 - 1.5e-42 145.6 0.0 2.1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74717.1 - 1.9e-38 132.4 0.0 2.6e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain F-box-like PF12937.7 KNZ74718.1 - 7.6e-07 28.9 2.4 7.6e-07 28.9 2.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ74718.1 - 0.022 14.6 6.1 0.53 10.2 1.3 2.9 2 0 0 2 2 2 0 F-box domain Ribosomal_L7Ae PF01248.26 KNZ74719.1 - 1.2e-21 76.2 1.0 2.2e-21 75.4 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Toprim_3 PF13362.6 KNZ74719.1 - 0.083 13.3 0.4 1.1 9.6 0.1 2.3 1 1 1 2 2 2 0 Toprim domain CLPTM1 PF05602.12 KNZ74719.1 - 0.092 11.7 0.4 0.12 11.3 0.4 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) AAA PF00004.29 KNZ74720.1 - 2e-14 54.1 0.0 4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ74720.1 - 0.033 14.4 2.1 0.45 10.8 0.0 2.8 2 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KNZ74720.1 - 0.066 13.6 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 KNZ74720.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KNZ74720.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ELP6 PF09807.9 KNZ74721.1 - 4.3e-18 65.6 0.0 3.2e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 KNZ74721.1 - 2e-07 30.8 0.3 2.6e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 ERCC4 PF02732.15 KNZ74722.1 - 5.9e-17 62.3 0.0 1.1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Beta_protein PF14350.6 KNZ74722.1 - 0.012 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Beta protein SWI-SNF_Ssr4 PF08549.10 KNZ74722.1 - 0.06 12.0 0.4 0.089 11.4 0.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Cir_N PF10197.9 KNZ74723.1 - 9.1e-07 29.0 0.8 9.1e-07 29.0 0.8 4.1 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF5112 PF17139.4 KNZ74723.1 - 0.36 10.3 1.6 0.68 9.4 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) Barttin PF15462.6 KNZ74723.1 - 2.5 7.8 5.4 1.1 9.0 1.9 1.9 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Pkinase_Tyr PF07714.17 KNZ74724.1 - 5e-35 121.0 0.0 5.3e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ74724.1 - 1.8e-33 116.0 0.0 6.3e-24 84.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 KNZ74724.1 - 0.0049 16.3 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ74724.1 - 0.083 12.5 2.6 0.32 10.6 0.0 2.6 3 0 0 3 3 3 0 RIO1 family APH PF01636.23 KNZ74724.1 - 0.083 12.8 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.7 KNZ74725.1 - 4.9e-07 29.5 0.7 1.6e-06 27.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ74725.1 - 0.00046 20.0 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 F-box domain Ribosomal_L5 PF00281.19 KNZ74725.1 - 0.088 13.2 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L5 Pkinase_Tyr PF07714.17 KNZ74726.1 - 6.9e-28 97.6 0.0 9.5e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74726.1 - 1.5e-24 86.8 0.0 2.3e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ74726.1 - 0.0081 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ74726.1 - 0.023 14.0 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KNZ74726.1 - 0.039 13.9 0.3 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KNZ74730.1 - 1.7e-36 125.9 0.0 9.7e-36 123.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74730.1 - 3.1e-33 115.3 0.0 5.9e-32 111.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KNZ74730.1 - 2.8e-05 23.6 0.0 7.4e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ74730.1 - 7.1e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ74730.1 - 0.0063 16.1 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KNZ74730.1 - 0.0082 15.0 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ74730.1 - 0.013 15.4 0.2 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ74730.1 - 0.033 13.1 0.0 0.043 12.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KNZ74730.1 - 0.06 13.0 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_Tyr PF07714.17 KNZ74731.1 - 4.3e-39 134.4 0.0 5.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74731.1 - 3.2e-36 125.0 0.0 4e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KNZ74731.1 - 2.9e-05 23.6 0.0 4.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ74731.1 - 0.0004 20.4 0.0 0.00069 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ74731.1 - 0.00044 19.7 0.1 0.00065 19.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ74731.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KNZ74731.1 - 0.0011 17.8 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 KNZ74731.1 - 0.095 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_Tyr PF07714.17 KNZ74732.1 - 1.9e-19 70.0 0.0 5.1e-13 48.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ74732.1 - 2.5e-18 66.4 0.0 4e-14 52.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain PSP1 PF04468.12 KNZ74732.1 - 4.3e-11 42.9 1.2 1.5e-10 41.2 0.2 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region PBD PF00786.28 KNZ74733.1 - 2.5e-19 69.4 7.1 8.6e-11 42.0 1.6 2.6 3 0 0 3 3 3 2 P21-Rho-binding domain PH PF00169.29 KNZ74733.1 - 5e-11 43.0 0.1 4.6e-05 23.9 0.0 2.7 2 1 0 2 2 2 2 PH domain G-alpha PF00503.20 KNZ74734.1 - 8.7e-92 308.0 0.4 5.8e-73 246.1 0.4 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Arf PF00025.21 KNZ74734.1 - 9.9e-10 38.1 1.8 2.1e-05 24.1 0.0 2.9 3 1 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ74734.1 - 0.017 15.2 0.0 2.3 8.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 KNZ74734.1 - 0.12 12.6 0.1 1.5 9.1 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KNZ74734.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 KNZ74734.1 - 0.17 10.9 0.2 0.46 9.5 0.1 1.7 2 0 0 2 2 2 0 MCM P-loop domain Kelch_5 PF13854.6 KNZ74735.1 - 1.8e-13 50.1 0.0 4.6e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 KNZ74735.1 - 3.1e-12 45.9 1.0 9.9e-06 25.1 0.2 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 KNZ74735.1 - 4e-12 46.0 1.2 8.2e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ74735.1 - 6.5e-11 42.1 1.1 2.7e-05 24.3 0.4 2.2 1 1 1 2 2 2 2 Kelch motif Kelch_3 PF13415.6 KNZ74735.1 - 5.7e-09 36.0 2.0 3.9e-05 23.8 0.0 3.2 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KNZ74735.1 - 6.7e-07 29.0 0.9 0.0062 16.5 0.0 2.3 2 0 0 2 2 2 2 Kelch motif Ricin_B_lectin PF00652.22 KNZ74736.1 - 5.5e-23 81.6 0.4 7.8e-23 81.1 0.4 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KNZ74736.1 - 6.5e-15 55.6 2.4 5.4e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pea-VEAacid PF08111.11 KNZ74736.1 - 0.024 14.9 0.1 0.047 14.0 0.1 1.5 1 0 0 1 1 1 0 Pea-VEAacid family Ricin_B_lectin PF00652.22 KNZ74737.1 - 2.2e-23 82.9 0.6 3.2e-23 82.3 0.6 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KNZ74737.1 - 1.7e-14 54.3 3.6 8.3e-07 29.6 0.0 2.2 1 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pea-VEAacid PF08111.11 KNZ74737.1 - 0.009 16.2 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Pea-VEAacid family CDtoxinA PF03498.14 KNZ74737.1 - 0.018 14.6 0.8 0.16 11.6 0.0 2.1 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain DUF4598 PF15370.6 KNZ74738.1 - 3.9e-11 43.4 0.0 6.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4598) DUF3246 PF11596.8 KNZ74738.1 - 0.0037 16.7 0.7 0.0044 16.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) UbiA PF01040.18 KNZ74738.1 - 0.17 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family Chromo PF00385.24 KNZ74740.1 - 3.6e-15 55.6 0.1 4.8e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ74740.1 - 0.037 14.2 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 KNZ74740.1 - 0.04 13.8 1.1 0.052 13.4 1.1 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Ribonuc_2-5A PF06479.12 KNZ74741.1 - 0.011 15.9 0.0 0.028 14.6 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease 2-5A FAP206 PF12018.8 KNZ74741.1 - 0.21 11.1 0.6 0.28 10.6 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function RCC1 PF00415.18 KNZ74742.1 - 1.4e-33 115.2 13.5 1.3e-06 28.9 0.0 6.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNZ74742.1 - 1.8e-15 56.3 22.6 0.00016 21.4 0.2 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 KNZ74742.1 - 5.3e-10 39.0 5.5 5.3e-10 39.0 5.5 2.6 2 0 0 2 2 2 1 PHD-finger SNX17_FERM_C PF18116.1 KNZ74742.1 - 0.0038 17.3 0.5 15 5.7 0.0 3.5 3 0 0 3 3 3 2 Sorting Nexin 17 FERM C-terminal domain Prok-RING_1 PF14446.6 KNZ74742.1 - 0.071 13.0 3.4 0.17 11.8 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KNZ74742.1 - 5.5 6.6 11.1 12 5.6 1.1 3.7 3 0 0 3 3 3 0 PHD-finger GMC_oxred_N PF00732.19 KNZ74743.1 - 4e-69 233.3 0.0 5.1e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ74743.1 - 2.3e-32 112.5 0.1 3.7e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ74743.1 - 0.00066 19.9 0.0 0.0034 17.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ74743.1 - 0.0023 17.1 0.1 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ74743.1 - 0.0031 16.6 0.7 0.04 13.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KNZ74743.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KNZ74743.1 - 0.031 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KNZ74743.1 - 0.057 13.7 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KNZ74743.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lipase_GDSL_2 PF13472.6 KNZ74744.1 - 0.0015 19.0 1.7 0.0035 17.8 1.7 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KNZ74744.1 - 0.031 14.2 0.1 0.093 12.7 0.1 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF3097 PF11296.8 KNZ74744.1 - 0.18 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) Glyco_hydro_92 PF07971.12 KNZ74745.1 - 8.9e-111 371.0 0.0 1.1e-110 370.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KNZ74745.1 - 9.7e-05 22.4 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain GMC_oxred_N PF00732.19 KNZ74746.1 - 4.7e-62 210.0 0.0 6.1e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ74746.1 - 1.1e-35 123.3 0.8 3.9e-35 121.5 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KNZ74746.1 - 0.00012 21.3 0.0 0.00019 20.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ74746.1 - 0.00025 21.2 0.0 0.00074 19.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ74746.1 - 0.0033 17.1 0.4 0.064 12.8 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ74746.1 - 0.0062 15.7 0.1 0.18 10.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ74746.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ74746.1 - 0.077 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KNZ74746.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KNZ74746.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Med3 PF11593.8 KNZ74747.1 - 2.7 7.1 9.8 3.4 6.7 9.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hamartin PF04388.12 KNZ74747.1 - 9.8 4.7 8.9 11 4.5 8.9 1.0 1 0 0 1 1 1 0 Hamartin protein Retrotran_gag_2 PF14223.6 KNZ74748.1 - 1.1e-19 70.5 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KNZ74748.1 - 0.0024 17.9 1.1 0.0045 17.0 1.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Vps36-NZF-N PF16988.5 KNZ74748.1 - 0.29 10.6 0.1 0.29 10.6 0.1 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Methyltransf_15 PF09445.10 KNZ74749.1 - 2.4e-37 128.0 0.0 4.8e-28 97.8 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KNZ74749.1 - 5.6e-07 30.2 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ74749.1 - 3.1e-05 23.8 0.0 4.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 KNZ74749.1 - 6.4e-05 22.7 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 KNZ74749.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 KNZ74749.1 - 0.00044 20.8 0.0 0.0012 19.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 KNZ74749.1 - 0.0043 16.8 0.1 0.054 13.2 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KNZ74749.1 - 0.005 16.3 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 KNZ74749.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SAM_MT PF04445.13 KNZ74749.1 - 0.035 13.5 0.0 0.055 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase tRNA_U5-meth_tr PF05958.11 KNZ74749.1 - 0.062 12.3 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.16 KNZ74749.1 - 0.096 11.8 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FAD_binding_3 PF01494.19 KNZ74750.1 - 2.9e-18 66.2 0.0 4.7e-08 32.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 KNZ74750.1 - 7.7e-06 25.0 1.0 0.00037 19.5 0.1 3.1 3 1 1 4 4 4 1 Tryptophan halogenase NAD_binding_8 PF13450.6 KNZ74750.1 - 2.8e-05 24.3 0.3 9.9e-05 22.5 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KNZ74750.1 - 0.0032 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family SE PF08491.10 KNZ74750.1 - 0.012 14.7 0.0 0.056 12.5 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 KNZ74750.1 - 0.017 14.4 0.1 0.14 11.4 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ74750.1 - 0.13 11.2 1.4 12 4.8 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 KNZ74750.1 - 0.28 10.7 2.9 0.73 9.4 2.9 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Nup35_RRM PF05172.13 KNZ74751.1 - 2.9e-08 33.6 0.0 1.8e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KNZ74752.1 - 0.00066 19.5 0.0 0.0018 18.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M28 PF04389.17 KNZ74754.1 - 6.3e-32 110.9 0.1 9.8e-32 110.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PTPA PF03095.15 KNZ74755.1 - 2.4e-124 414.7 0.0 2.7e-124 414.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNA_pol_Rpo13 PF12136.8 KNZ74756.1 - 0.68 9.9 6.5 1.5 8.8 6.5 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain GMC_oxred_N PF00732.19 KNZ74757.1 - 6.2e-62 209.6 0.0 7.9e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ74757.1 - 8.8e-35 120.3 0.9 2.4e-34 118.9 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KNZ74757.1 - 0.00013 21.2 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ74757.1 - 0.00027 21.1 0.0 0.0008 19.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ74757.1 - 0.0039 16.8 0.6 0.069 12.7 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ74757.1 - 0.0066 15.6 0.0 0.22 10.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ74757.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ74757.1 - 0.071 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 KNZ74757.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 KNZ74757.1 - 0.21 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PIF1 PF05970.14 KNZ74758.1 - 3.3e-34 118.6 0.0 3.8e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase SUIM_assoc PF16619.5 KNZ74759.1 - 3.7 7.7 14.4 1.1 9.4 7.3 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Serglycin PF04360.12 KNZ74759.1 - 4 7.4 6.4 0.45 10.4 1.2 2.0 2 0 0 2 2 2 0 Serglycin NDUF_B6 PF09782.9 KNZ74760.1 - 0.14 12.3 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF5450 PF17529.2 KNZ74760.1 - 0.15 12.2 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5450) FtsX PF02687.21 KNZ74761.1 - 0.028 14.9 0.2 0.028 14.9 0.2 3.4 3 1 0 3 3 3 0 FtsX-like permease family Bac_export_2 PF01312.19 KNZ74761.1 - 1.6 7.8 3.9 2.7 7.1 3.9 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Fig1 PF12351.8 KNZ74761.1 - 2.1 8.2 6.3 24 4.8 0.0 3.1 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 TRP PF06011.12 KNZ74761.1 - 2.4 6.8 10.5 0.013 14.3 1.0 1.8 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel F-box-like PF12937.7 KNZ74762.1 - 9.2e-07 28.7 0.3 4e-06 26.6 0.3 2.1 1 0 0 1 1 1 1 F-box-like LRV PF01816.17 KNZ74762.1 - 7.1 7.3 6.0 20 5.9 0.3 3.0 2 0 0 2 2 2 0 Leucine rich repeat variant DUF3535 PF12054.8 KNZ74764.1 - 1.7e-99 334.0 0.1 2.5e-98 330.2 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KNZ74764.1 - 2.7e-66 223.7 0.1 4.9e-66 222.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ74764.1 - 1e-16 61.2 0.0 2.4e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KNZ74764.1 - 1e-09 37.8 15.0 1 9.8 0.0 9.0 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 KNZ74764.1 - 0.0026 18.3 7.8 32 5.2 0.0 7.1 7 0 0 7 7 7 0 HEAT-like repeat ResIII PF04851.15 KNZ74764.1 - 0.0068 16.4 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNZ74764.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SOG2 PF10428.9 KNZ74765.1 - 2.4e-79 267.9 2.5 2.4e-79 267.9 2.5 3.0 2 1 0 2 2 2 1 RAM signalling pathway protein Cupin_8 PF13621.6 KNZ74765.1 - 1.1e-16 61.4 0.0 2.1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain LRR_8 PF13855.6 KNZ74765.1 - 1.4e-16 59.9 7.4 7.4e-10 38.4 4.7 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 KNZ74765.1 - 1.7e-13 50.5 12.4 5.5e-05 23.4 0.0 3.8 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNZ74765.1 - 9.8e-05 22.4 1.1 1e+02 4.1 0.1 6.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_9 PF14580.6 KNZ74765.1 - 0.0039 16.7 0.2 0.01 15.4 0.1 1.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 KNZ74765.1 - 0.0053 16.7 2.0 14 6.0 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat UCH_1 PF13423.6 KNZ74766.1 - 1.8e-79 267.7 0.1 2.5e-79 267.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KNZ74766.1 - 2.4e-19 70.5 0.0 4.2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease TF_Zn_Ribbon PF08271.12 KNZ74766.1 - 0.062 12.8 1.4 0.11 12.0 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding WD40 PF00400.32 KNZ74766.1 - 5.6 8.0 8.1 3.8e+02 2.2 0.1 5.4 5 1 0 5 5 5 0 WD domain, G-beta repeat dsDNA_bind PF01984.20 KNZ74767.1 - 3.5e-20 72.3 5.1 4.6e-16 59.1 0.5 2.0 2 0 0 2 2 2 2 Double-stranded DNA-binding domain DUF1221 PF06760.11 KNZ74767.1 - 0.086 12.3 0.2 0.1 12.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) MUG113 PF13455.6 KNZ74768.1 - 6.3e-15 55.6 0.0 3.2e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KNZ74768.1 - 3.5e-11 43.6 0.0 1.2e-07 32.2 0.0 2.6 2 0 0 2 2 2 2 T5orf172 domain Dickkopf_N PF04706.12 KNZ74768.1 - 3.3 8.3 5.5 3 8.4 3.6 2.0 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region UDG PF03167.19 KNZ74770.1 - 9.9e-20 71.1 0.0 1.4e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Rota_NS35 PF02509.14 KNZ74770.1 - 0.0089 15.1 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Rotavirus non-structural protein 35 FYVE PF01363.21 KNZ74771.1 - 4.3e-17 62.0 3.1 7.1e-17 61.3 3.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 KNZ74771.1 - 2.4e-16 59.2 1.9 2.4e-16 59.2 1.9 2.0 2 0 0 2 2 2 1 Rabenosyn Rab binding domain FYVE_2 PF02318.16 KNZ74771.1 - 0.0067 16.6 1.3 0.021 15.1 1.3 1.8 1 0 0 1 1 1 1 FYVE-type zinc finger zf-C2HC5 PF06221.13 KNZ74771.1 - 0.037 14.0 8.9 0.051 13.6 6.6 2.1 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Occludin_ELL PF07303.13 KNZ74771.1 - 0.2 12.4 2.4 0.29 11.9 0.4 2.1 2 0 0 2 2 2 0 Occludin homology domain IBR PF01485.21 KNZ74771.1 - 0.82 9.9 8.4 0.21 11.8 5.1 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Mod_r PF07200.13 KNZ74771.1 - 2 8.5 6.7 1.9 8.6 0.4 2.4 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cofilin_ADF PF00241.20 KNZ74772.1 - 3.9e-33 113.8 0.0 6.1e-19 68.0 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Lysine_decarbox PF03641.14 KNZ74773.1 - 6.8e-33 113.6 0.0 9.9e-33 113.0 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KNZ74773.1 - 7.1e-10 38.7 0.1 1.1e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family tRNA-synt_1b PF00579.25 KNZ74774.1 - 7.2e-22 78.1 0.0 2.4e-21 76.3 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-RING_4 PF14570.6 KNZ74775.1 - 3.2e-17 62.1 7.3 5.2e-17 61.4 7.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KNZ74775.1 - 0.0021 17.9 6.2 0.004 17.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KNZ74775.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 KNZ74775.1 - 0.046 13.6 5.2 0.11 12.4 5.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 KNZ74775.1 - 0.18 11.9 2.8 0.44 10.7 2.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 KNZ74775.1 - 0.43 10.5 3.3 0.88 9.5 3.3 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) FAD-oxidase_C PF02913.19 KNZ74776.1 - 1.6e-55 188.4 0.0 2.3e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KNZ74776.1 - 4e-27 94.6 0.0 7.5e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain PAD PF03068.15 KNZ74776.1 - 0.061 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) MS_channel PF00924.18 KNZ74777.1 - 2.9e-17 62.9 1.0 5.5e-17 62.0 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 KNZ74777.1 - 7.3e-05 22.0 0.2 0.0002 20.7 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KNZ74777.1 - 0.00053 19.7 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KNZ74777.1 - 0.0015 19.0 0.1 0.0031 17.9 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair Wzy_C PF04932.15 KNZ74777.1 - 0.0022 17.6 4.7 0.066 12.9 0.3 2.3 2 0 0 2 2 2 2 O-Antigen ligase EF-hand_5 PF13202.6 KNZ74777.1 - 0.013 14.9 0.2 0.05 13.1 0.2 2.0 1 0 0 1 1 1 0 EF hand Auxin_canalis PF05703.11 KNZ74777.1 - 0.048 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Auxin canalisation DUF2207 PF09972.9 KNZ74777.1 - 0.051 12.3 0.9 0.16 10.7 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3098 PF11297.8 KNZ74777.1 - 0.079 12.6 0.8 0.24 11.0 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) PBP1_TM PF14812.6 KNZ74777.1 - 0.088 13.2 0.0 0.088 13.2 0.0 2.5 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SUR7 PF06687.12 KNZ74777.1 - 5.4 6.6 10.2 9.5 5.8 1.1 2.5 2 0 0 2 2 2 0 SUR7/PalI family HSA PF07529.13 KNZ74778.1 - 3.8e-11 43.1 0.1 3.8e-11 43.1 0.1 2.9 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 KNZ74778.1 - 1.8e-06 28.1 1.1 3.6e-06 27.1 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KNZ74778.1 - 5.3e-05 23.3 2.0 9.7e-05 22.5 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 KNZ74778.1 - 0.069 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Cellulase PF00150.18 KNZ74779.1 - 3e-10 40.0 0.0 5.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4462 PF14692.6 KNZ74780.1 - 0.14 11.6 0.2 0.22 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Pectate_lyase_3 PF12708.7 KNZ74781.1 - 4.5e-82 275.1 19.9 3.4e-75 252.6 14.7 3.5 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KNZ74781.1 - 0.0016 18.1 0.4 0.004 16.8 0.4 1.7 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase CDC45 PF02724.14 KNZ74782.1 - 6.7e-205 682.1 0.0 8e-205 681.9 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 KNZ74782.1 - 0.0069 16.5 1.7 0.01 16.0 1.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Spt5_N PF11942.8 KNZ74782.1 - 0.22 12.5 7.3 0.46 11.5 7.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Scramblase PF03803.15 KNZ74783.1 - 4.8e-43 147.0 0.0 3.6e-32 111.4 0.0 2.0 1 1 1 2 2 2 2 Scramblase GTP_EFTU PF00009.27 KNZ74784.1 - 1e-33 116.6 1.3 4.7e-32 111.1 1.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KNZ74784.1 - 9.1e-31 106.1 0.5 3.3e-30 104.3 0.5 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KNZ74784.1 - 1.9e-08 34.3 0.5 1.2e-07 31.8 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KNZ74784.1 - 0.00049 20.3 0.0 0.00089 19.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IF2_N PF04760.15 KNZ74784.1 - 0.0006 19.6 0.1 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region PduV-EutP PF10662.9 KNZ74784.1 - 0.0063 16.3 0.4 3.2 7.5 0.1 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 KNZ74784.1 - 0.016 14.6 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CHORD PF04968.12 KNZ74785.1 - 6.8e-36 122.8 6.7 1.1e-22 80.5 1.3 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 KNZ74785.1 - 9.8e-16 58.5 0.3 1.8e-15 57.7 0.3 1.5 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.27 KNZ74785.1 - 2.4e-09 37.0 0.1 0.0041 17.0 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein BTK PF00779.19 KNZ74785.1 - 0.075 12.9 3.6 6.1 6.8 0.1 3.2 3 0 0 3 3 3 0 BTK motif 2OG-FeII_Oxy_2 PF13532.6 KNZ74786.1 - 2.8e-11 44.0 0.6 5.4e-11 43.0 0.6 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KNZ74788.1 - 6.2e-08 32.3 0.3 2.3e-07 30.5 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74788.1 - 0.00024 20.5 0.2 0.0015 17.8 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Herpes_Helicase PF02689.14 KNZ74789.1 - 0.00027 19.0 0.0 0.00027 19.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ74789.1 - 0.06 13.2 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ImcF-related_N PF14331.6 KNZ74790.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain MLD PF11647.8 KNZ74791.1 - 0.027 14.7 0.4 0.065 13.5 0.4 1.7 1 0 0 1 1 1 0 Membrane Localization Domain HsbA PF12296.8 KNZ74792.1 - 1.4e-05 25.5 6.8 0.0016 18.9 0.7 2.6 2 1 1 3 3 3 2 Hydrophobic surface binding protein A Xrn1_D3 PF18194.1 KNZ74792.1 - 0.0035 17.4 0.1 0.0075 16.3 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Pex2_Pex12 PF04757.14 KNZ74793.1 - 5.4e-35 121.0 7.1 7.5e-35 120.5 7.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 KNZ74793.1 - 0.0026 17.7 0.6 0.013 15.5 0.2 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-4CXXC_R1 PF10497.9 KNZ74793.1 - 0.029 14.6 0.3 0.054 13.7 0.1 1.4 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C3HC4_4 PF15227.6 KNZ74793.1 - 0.079 13.1 1.0 0.21 11.8 1.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KNZ74793.1 - 0.11 12.3 0.8 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KNZ74793.1 - 0.46 10.7 3.2 0.36 11.0 0.9 1.8 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_2 PF13639.6 KNZ74793.1 - 0.77 10.1 2.9 2.5 8.5 0.4 2.3 2 0 0 2 2 2 0 Ring finger domain IBN_N PF03810.19 KNZ74794.1 - 0.00052 19.9 0.1 0.011 15.6 0.1 3.1 3 1 1 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KNZ74794.1 - 0.011 15.8 0.0 0.049 13.7 0.0 2.2 2 0 0 2 2 2 0 Exportin 1-like protein Slx4 PF09494.10 KNZ74795.1 - 0.00051 19.9 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Mur_ligase_M PF08245.12 KNZ74796.1 - 4.3e-08 33.4 0.4 0.00083 19.4 0.1 3.7 2 1 1 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 KNZ74796.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain BRCT_2 PF16589.5 KNZ74797.1 - 1.3e-09 38.4 0.0 2.9e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KNZ74797.1 - 1.7e-06 28.3 0.0 1.2e-05 25.5 0.0 2.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 KNZ74797.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 KNZ74797.1 - 0.00029 21.1 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KNZ74797.1 - 0.093 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Vps52 PF04129.12 KNZ74799.1 - 3.3e-56 191.1 1.1 7.5e-42 143.7 0.0 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 KNZ74799.1 - 0.00031 19.3 1.2 0.00099 17.6 0.1 2.2 2 1 0 2 2 2 1 Exocyst complex component Sec3 HrpE PF06188.12 KNZ74799.1 - 0.00055 19.9 0.7 0.0026 17.7 0.3 2.1 2 0 0 2 2 2 1 HrpE/YscL/FliH and V-type ATPase subunit E DIT1_PvcA PF05141.12 KNZ74799.1 - 0.017 14.6 0.2 0.87 9.0 0.1 2.2 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein COG2 PF06148.11 KNZ74799.1 - 0.23 11.6 2.2 0.27 11.3 0.3 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 JAB PF01398.21 KNZ74801.1 - 2.6e-32 111.3 0.2 4.4e-32 110.5 0.2 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KNZ74801.1 - 6.6e-13 49.1 1.1 1.2e-12 48.2 1.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KNZ74801.1 - 2.6e-06 27.2 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 KNZ74801.1 - 0.016 15.3 0.3 0.031 14.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) UPF0172 PF03665.13 KNZ74801.1 - 0.086 12.9 0.8 0.22 11.6 0.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.20 KNZ74802.1 - 3.6e-16 59.1 0.1 7.1e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.25 KNZ74803.1 - 2.4e-60 204.2 0.0 1.2e-40 139.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ74803.1 - 5.5e-27 94.7 0.0 3.6e-22 78.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KNZ74803.1 - 1e-12 48.2 0.0 2e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KNZ74803.1 - 1.1e-07 31.5 0.2 0.00064 19.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KNZ74803.1 - 0.0023 17.9 1.5 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 KNZ74803.1 - 0.0026 17.4 0.1 2.9 7.4 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 KNZ74803.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KNZ74803.1 - 0.013 14.9 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KNZ74803.1 - 0.042 12.9 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 KNZ74803.1 - 0.097 12.3 0.1 0.29 10.7 0.1 1.8 1 0 0 1 1 1 0 RIO1 family THOC7 PF05615.13 KNZ74805.1 - 5e-34 117.4 7.1 5e-34 117.4 7.1 1.8 2 0 0 2 2 2 1 Tho complex subunit 7 SlyX PF04102.12 KNZ74805.1 - 0.00092 19.8 0.6 0.6 10.8 0.0 2.9 2 0 0 2 2 2 1 SlyX zf-C4H2 PF10146.9 KNZ74805.1 - 0.0042 17.4 4.6 0.0064 16.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein DUF4482 PF14818.6 KNZ74805.1 - 0.021 15.7 2.4 0.048 14.5 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Cortex-I_coil PF09304.10 KNZ74805.1 - 0.039 14.2 9.2 0.06 13.6 0.3 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil PIN_8 PF18476.1 KNZ74805.1 - 0.069 13.0 4.3 0.12 12.3 4.3 1.3 1 0 0 1 1 1 0 PIN like domain Cep57_MT_bd PF06657.13 KNZ74805.1 - 0.46 11.0 6.3 5.5 7.5 1.7 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 KNZ74805.1 - 2.1 8.4 4.7 2.8 8.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Lactamase_B_2 PF12706.7 KNZ74806.1 - 4.9e-10 39.3 0.8 7.3e-08 32.2 0.8 3.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KNZ74806.1 - 0.0096 15.9 2.3 0.032 14.2 0.7 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.15 KNZ74806.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II RhoGEF PF00621.20 KNZ74808.1 - 1.1e-33 117.0 0.0 2.8e-33 115.7 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain GAS PF13851.6 KNZ74808.1 - 0.82 9.0 12.6 0.42 9.9 3.9 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFP_35_N PF07334.13 KNZ74808.1 - 3.2 7.9 6.3 5 7.3 0.3 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3496 PF12001.8 KNZ74808.1 - 6 7.3 10.4 0.61 10.5 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) RhoGEF PF00621.20 KNZ74809.1 - 1.1e-21 77.9 0.1 5.7e-11 43.0 0.0 2.5 2 1 0 2 2 2 2 RhoGEF domain SOAR PF16533.5 KNZ74809.1 - 0.051 13.5 0.9 0.13 12.3 0.9 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region tRNA-synt_2 PF00152.20 KNZ74809.1 - 0.052 12.6 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) PH PF00169.29 KNZ74809.1 - 0.12 12.9 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 PH domain LRR_6 PF13516.6 KNZ74810.1 - 6e-13 47.7 10.5 0.029 14.4 0.1 8.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 KNZ74810.1 - 1.4e-11 44.4 3.1 0.18 12.3 0.0 7.1 5 3 4 9 9 9 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNZ74810.1 - 2.1e-05 24.4 13.8 7.1 7.6 0.0 7.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 KNZ74810.1 - 0.043 13.6 2.7 14 5.6 0.0 4.6 4 2 1 5 5 5 0 Leucine rich repeat DUF5310 PF17237.2 KNZ74811.1 - 8.7e-21 73.5 2.7 1.2e-20 73.0 2.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Amidohydro_3 PF07969.11 KNZ74812.1 - 4.6e-15 56.0 2.8 1.5e-08 34.6 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KNZ74812.1 - 3e-09 36.6 0.0 3.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Myb_DNA-binding PF00249.31 KNZ74813.1 - 7.5e-20 70.9 3.4 1.6e-08 34.6 0.0 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ74813.1 - 5.3e-14 52.2 0.8 1.5e-08 34.8 0.0 3.9 2 1 2 4 4 4 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KNZ74813.1 - 0.0023 18.0 0.0 0.015 15.4 0.0 2.4 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain HCV_NS5a_C PF12941.7 KNZ74813.1 - 0.037 13.9 0.8 0.054 13.3 0.8 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF676 PF05057.14 KNZ74814.1 - 6.4e-05 22.6 0.0 0.00019 21.0 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KNZ74814.1 - 0.00093 19.9 0.5 0.00093 19.9 0.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 KNZ74814.1 - 0.017 14.4 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 KNZ74814.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 KNZ74814.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 KNZ74814.1 - 0.077 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 KNZ74814.1 - 0.1 12.1 0.0 0.58 9.6 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 KNZ74814.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DctQ PF04290.12 KNZ74814.1 - 0.15 12.0 0.3 0.65 9.9 0.1 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Acetyltransf_1 PF00583.25 KNZ74815.1 - 3.5e-12 46.6 0.0 4.3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ74815.1 - 5.9e-09 35.9 0.0 6.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ74815.1 - 1.1e-06 28.9 0.0 1.5e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ74815.1 - 0.0002 21.3 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 KNZ74815.1 - 0.0035 16.8 0.2 0.0035 16.8 0.2 1.5 2 0 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KNZ74815.1 - 0.0073 16.4 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAF-AH_p_II PF03403.13 KNZ74816.1 - 3.1e-32 111.5 0.0 1.9e-31 109.0 0.0 2.0 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 KNZ74816.1 - 1.2e-06 28.0 0.0 0.0014 17.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KNZ74816.1 - 3.5e-05 22.9 0.0 0.00095 18.1 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 KNZ74816.1 - 0.002 18.8 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 KNZ74816.1 - 0.0031 16.6 0.0 0.014 14.4 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase Thioesterase PF00975.20 KNZ74816.1 - 0.06 13.5 0.1 7.5 6.6 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain DLH PF01738.18 KNZ74816.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Glyco_hydro_79C PF16862.5 KNZ74817.1 - 6.2e-08 33.5 0.0 1.9e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain F-box-like PF12937.7 KNZ74818.1 - 7e-11 41.9 0.8 7e-11 41.9 0.8 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KNZ74818.1 - 1.9e-08 34.5 11.7 0.41 11.1 0.0 6.7 6 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KNZ74818.1 - 3.8e-06 26.5 18.8 24 5.3 0.0 10.3 11 0 0 11 11 11 0 Leucine Rich repeat F-box PF00646.33 KNZ74818.1 - 0.0034 17.2 0.4 0.0034 17.2 0.4 3.8 3 0 0 3 3 3 1 F-box domain FtsA PF14450.6 KNZ74818.1 - 0.11 12.9 0.0 0.94 9.9 0.0 2.4 2 1 0 2 2 2 0 Cell division protein FtsA SAM_Ste50p PF09235.10 KNZ74818.1 - 0.12 12.6 5.9 12 6.2 0.2 3.7 3 1 0 3 3 3 0 Ste50p, sterile alpha motif DUF2718 PF10918.8 KNZ74818.1 - 0.13 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) NOA36 PF06524.12 KNZ74818.1 - 2 7.7 4.3 23 4.2 0.0 2.2 2 0 0 2 2 2 0 NOA36 protein DUF4050 PF13259.6 KNZ74819.1 - 0.091 13.1 1.2 1.3 9.3 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4050) LSM PF01423.22 KNZ74820.1 - 1.7e-18 66.0 0.6 2.5e-18 65.5 0.6 1.3 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KNZ74820.1 - 0.036 14.2 0.1 0.073 13.2 0.0 1.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain zf-U1 PF06220.12 KNZ74821.1 - 2.1e-20 72.2 4.3 2.9e-20 71.7 4.3 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 KNZ74821.1 - 0.19 11.7 2.3 0.3 11.0 2.3 1.4 1 0 0 1 1 1 0 CLIP1 zinc knuckle DUF202 PF02656.15 KNZ74822.1 - 2.9e-15 56.5 4.0 3.2e-15 56.3 2.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2637 PF10935.8 KNZ74822.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) SANT_DAMP1_like PF16282.5 KNZ74823.1 - 7e-32 109.5 4.3 1.3e-31 108.7 4.3 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 KNZ74823.1 - 0.0089 16.2 0.0 0.041 14.1 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain DMAP1 PF05499.12 KNZ74823.1 - 0.065 13.1 1.2 0.39 10.6 1.2 2.0 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 KNZ74823.1 - 0.11 12.8 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain BRO1 PF03097.18 KNZ74824.1 - 6.3e-121 403.8 0.1 8.9e-121 403.3 0.1 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KNZ74824.1 - 2e-47 161.9 0.1 3.3e-47 161.2 0.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF543 PF04418.12 KNZ74825.1 - 1.5e-21 76.2 0.1 1.6e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) AAA PF00004.29 KNZ74826.1 - 8.6e-14 52.1 0.0 2.4e-13 50.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF1904 PF08921.11 KNZ74826.1 - 0.14 12.5 0.4 0.94 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) tRNA-synt_1c PF00749.21 KNZ74827.1 - 6.8e-108 360.3 0.0 9.4e-108 359.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 KNZ74827.1 - 9.4e-37 126.5 0.0 1.6e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 KNZ74827.1 - 7.2e-29 100.9 0.0 2.4e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 KNZ74827.1 - 1.7e-05 25.6 1.0 1.7e-05 25.6 1.0 2.3 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Tubulin PF00091.25 KNZ74828.1 - 1.9e-64 217.5 0.0 2.5e-64 217.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KNZ74828.1 - 2e-49 166.9 0.0 3.2e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KNZ74828.1 - 0.0021 17.8 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Abhydrolase_3 PF07859.13 KNZ74829.1 - 2.9e-38 131.9 0.0 1.9e-30 106.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KNZ74829.1 - 9.9e-11 41.1 0.0 4e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 KNZ74829.1 - 0.085 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family Lactamase_B_6 PF16661.5 KNZ74830.1 - 3.2e-50 170.2 0.0 4.6e-49 166.5 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KNZ74830.1 - 6.1e-26 91.6 7.9 3e-23 82.9 0.1 3.6 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KNZ74830.1 - 1e-20 74.0 0.0 3.5e-20 72.4 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 KNZ74830.1 - 1.1e-05 25.2 0.0 3.6e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Nucleo_P87 PF07267.11 KNZ74830.1 - 2 7.1 6.6 3.1 6.5 6.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Phage_tail_APC PF16778.5 KNZ74830.1 - 3.1 7.7 5.6 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Phage tail assembly chaperone protein CSRNP_N PF16019.5 KNZ74830.1 - 7.8 6.3 5.9 24 4.8 3.9 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Tubulin PF00091.25 KNZ74831.1 - 4.1e-67 226.2 0.0 5.5e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KNZ74831.1 - 2.4e-46 157.0 0.0 3.7e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KNZ74831.1 - 0.00089 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.25 KNZ74831.1 - 0.053 13.4 0.0 7.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) HAD_2 PF13419.6 KNZ74832.1 - 2.7e-18 66.7 0.0 3.6e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ74832.1 - 6.9e-10 39.6 0.2 2.1e-08 34.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ74832.1 - 1.8e-07 31.1 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 KNZ74832.1 - 0.021 15.2 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sec15 PF04091.12 KNZ74833.1 - 3.1e-89 299.5 0.0 5.5e-89 298.7 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 KNZ74833.1 - 7.3e-08 32.7 0.4 7.3e-08 32.7 0.4 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 KNZ74833.1 - 1.4e-05 25.0 0.3 0.00026 20.9 0.1 2.9 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps51 PF08700.11 KNZ74833.1 - 1.6e-05 24.9 0.9 0.00012 22.1 0.1 3.0 2 0 0 2 2 2 1 Vps51/Vps67 Prominin PF05478.11 KNZ74833.1 - 0.0014 16.7 0.8 0.61 8.0 0.3 2.8 3 0 0 3 3 3 2 Prominin Cas_DxTHG PF09455.10 KNZ74833.1 - 0.0057 16.3 0.8 1.9 8.0 0.2 2.5 2 0 0 2 2 2 2 CRISPR-associated (Cas) DxTHG family COG2 PF06148.11 KNZ74833.1 - 0.024 14.7 0.8 0.024 14.7 0.8 2.3 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 KNZ74833.1 - 0.035 13.9 0.1 0.15 11.8 0.1 2.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Tape_meas_lam_C PF09718.10 KNZ74833.1 - 0.53 10.4 1.6 4.4 7.5 0.1 3.2 5 0 0 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Arf PF00025.21 KNZ74834.1 - 6.6e-79 263.4 0.1 7.5e-79 263.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KNZ74834.1 - 1.9e-14 53.9 0.0 2.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KNZ74834.1 - 3.2e-14 52.7 0.0 4e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KNZ74834.1 - 6.3e-13 48.6 1.0 4.7e-09 35.9 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KNZ74834.1 - 1.2e-12 47.7 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KNZ74834.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ74834.1 - 2.2e-06 27.7 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KNZ74834.1 - 0.0072 15.7 0.6 0.02 14.2 0.6 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase DSPc PF00782.20 KNZ74835.1 - 3.2e-28 98.2 0.0 3.7e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ74835.1 - 2.6e-05 23.9 0.0 3.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KNZ74835.1 - 0.0045 17.3 0.0 0.0058 16.9 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Myotub-related PF06602.14 KNZ74835.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF4551 PF15087.6 KNZ74836.1 - 4.3 6.1 12.7 4.9 5.9 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NOP19 PF10863.8 KNZ74837.1 - 0.0073 16.1 0.5 0.0073 16.1 0.5 2.3 2 1 0 2 2 2 1 Nucleolar protein 19 PGA2 PF07543.12 KNZ74837.1 - 1.5 8.8 10.9 1.5 8.8 0.8 2.8 3 0 0 3 3 3 0 Protein trafficking PGA2 Nucleo_P87 PF07267.11 KNZ74837.1 - 3.8 6.3 7.7 6.2 5.6 7.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SIP1 PF04938.12 KNZ74838.1 - 5.5e-27 94.9 0.1 8.5e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Utp12 PF04003.12 KNZ74838.1 - 0.0096 16.2 0.2 0.02 15.2 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF4942 PF13708.6 KNZ74838.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4942) QRPTase_C PF01729.19 KNZ74839.1 - 2.2e-38 131.7 0.0 4.8e-38 130.6 0.0 1.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 KNZ74839.1 - 1e-19 70.3 0.1 2.9e-19 68.9 0.1 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain GPI-anchored PF10342.9 KNZ74839.1 - 1.5e-10 41.7 1.9 2.5e-10 41.0 0.1 2.4 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidohydro_2 PF04909.14 KNZ74840.1 - 3.6e-26 92.6 0.0 5.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 KNZ74840.1 - 0.05 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase ERM PF00769.19 KNZ74841.1 - 0.0017 18.2 10.5 0.0021 17.9 10.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Fib_alpha PF08702.10 KNZ74841.1 - 0.011 15.9 5.0 0.011 15.9 5.0 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.6 KNZ74841.1 - 0.024 14.2 10.9 0.12 11.9 7.0 2.1 1 1 1 2 2 2 0 TMCO5 family Cep57_CLD_2 PF14197.6 KNZ74841.1 - 0.039 14.0 5.6 0.081 13.0 4.7 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Tweety PF04906.13 KNZ74841.1 - 0.042 12.5 2.5 0.06 12.0 2.5 1.2 1 0 0 1 1 1 0 Tweety Phage_GP20 PF06810.11 KNZ74841.1 - 0.075 12.8 6.5 0.038 13.8 3.0 1.9 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF3584 PF12128.8 KNZ74841.1 - 0.15 9.5 10.5 0.19 9.2 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.19 KNZ74841.1 - 0.17 9.8 6.6 0.22 9.4 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5344 PF17279.2 KNZ74841.1 - 0.24 12.0 3.9 0.29 11.7 0.1 2.6 1 1 2 3 3 3 0 Family of unknown function (DUF5344) DUF1664 PF07889.12 KNZ74841.1 - 0.29 11.2 2.3 0.95 9.5 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mt_ATP-synt_B PF05405.14 KNZ74841.1 - 0.36 10.4 8.8 0.097 12.3 4.1 1.9 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CHAD PF05235.14 KNZ74841.1 - 0.42 10.6 7.8 5.8 6.8 7.6 2.1 1 1 0 1 1 1 0 CHAD domain JIP_LZII PF16471.5 KNZ74841.1 - 0.58 10.4 9.2 3.2 8.0 1.6 2.8 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II DUF1043 PF06295.12 KNZ74841.1 - 0.63 10.1 7.1 2.8 7.9 5.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Exonuc_VII_L PF02601.15 KNZ74841.1 - 1.5 8.4 6.7 1.7 8.1 6.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 KNZ74841.1 - 1.5 8.9 11.3 1 9.4 9.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KNZ74841.1 - 1.9 6.9 3.1 2.4 6.6 3.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fzo_mitofusin PF04799.13 KNZ74841.1 - 2 8.0 6.9 1 8.9 3.3 2.2 1 1 2 3 3 3 0 fzo-like conserved region OmpH PF03938.14 KNZ74841.1 - 2.2 8.6 9.7 4.8 7.5 9.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 KNZ74841.1 - 2.2 8.9 10.8 58 4.3 10.8 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CorA PF01544.18 KNZ74841.1 - 2.9 7.1 5.8 3.9 6.7 5.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 KNZ74841.1 - 4.6 7.2 9.4 13 5.8 0.3 2.7 1 1 1 3 3 3 0 Prefoldin subunit CENP-H PF05837.12 KNZ74841.1 - 5.8 7.4 11.5 0.81 10.1 6.6 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 KNZ74841.1 - 6.5 5.9 6.6 11 5.2 6.6 1.5 1 1 0 1 1 1 0 TMPIT-like protein YlqD PF11068.8 KNZ74841.1 - 6.5 7.1 11.0 2.2 8.6 7.6 1.9 1 1 1 2 2 2 0 YlqD protein Gram_pos_anchor PF00746.21 KNZ74842.1 - 0.048 13.6 0.6 0.079 12.9 0.6 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif OppC_N PF12911.7 KNZ74842.1 - 3.4 7.7 5.3 26 4.9 5.3 2.3 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PIF1 PF05970.14 KNZ74843.1 - 1.1e-106 357.0 0.0 1.3e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74843.1 - 3.4e-08 33.4 0.0 5.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain 4HPAD_g_N PF18671.1 KNZ74843.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Viral_helicase1 PF01443.18 KNZ74843.1 - 0.059 13.1 0.2 0.12 12.1 0.2 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KNZ74843.1 - 0.078 13.4 0.0 0.12 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Helitron_like_N PF14214.6 KNZ74844.1 - 2.6e-36 125.7 0.1 5e-36 124.7 0.0 1.5 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ74844.1 - 0.00012 21.3 0.3 0.00024 20.3 0.3 1.5 1 1 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) POT1PC PF16686.5 KNZ74846.1 - 0.038 13.9 0.1 0.043 13.7 0.1 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein gag-asp_proteas PF13975.6 KNZ74847.1 - 6.5e-07 29.8 0.0 9.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ74847.1 - 3.8e-06 27.5 0.0 8.1e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KNZ74847.1 - 0.057 13.2 0.1 0.081 12.7 0.1 1.2 1 0 0 1 1 1 0 Aspartyl protease HNF-1_N PF04814.13 KNZ74848.1 - 0.069 13.8 0.1 0.084 13.5 0.1 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Herpes_pp85 PF04637.12 KNZ74848.1 - 0.26 9.7 0.3 0.28 9.5 0.3 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) RT_RNaseH_2 PF17919.1 KNZ74850.1 - 0.0028 17.6 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ74850.1 - 0.13 12.6 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase gag-asp_proteas PF13975.6 KNZ74851.1 - 0.0014 19.1 0.0 0.0048 17.4 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ74851.1 - 0.0052 17.4 0.0 0.021 15.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease DUF4820 PF16091.5 KNZ74852.1 - 0.083 12.2 1.4 0.13 11.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CoA_binding_2 PF13380.6 KNZ74857.1 - 3.6e-17 62.9 0.0 4.3e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.6 KNZ74858.1 - 7.4e-29 100.6 0.0 8.6e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain PALP PF00291.25 KNZ74859.1 - 6.8e-46 157.0 0.4 4.9e-44 150.9 0.4 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2002 PF09400.10 KNZ74859.1 - 0.017 15.1 0.0 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) PIG-U PF06728.13 KNZ74860.1 - 4.4e-65 220.2 26.1 5e-65 220.0 26.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U BRO1 PF03097.18 KNZ74861.1 - 1.5e-19 70.1 0.0 2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain SbcD_C PF12320.8 KNZ74861.1 - 0.036 14.4 0.1 13 6.1 0.0 2.5 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain NAD_kinase PF01513.21 KNZ74863.1 - 7.2e-60 202.6 0.0 9.2e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KNZ74863.1 - 0.0056 16.3 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PDZ_assoc PF10600.9 KNZ74864.1 - 0.07 14.0 4.1 0.13 13.1 4.1 1.4 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors XPG_I_2 PF12813.7 KNZ74865.1 - 9.3e-07 28.6 0.0 7.8e-05 22.3 0.0 3.3 4 1 0 4 4 4 1 XPG domain containing XPG_N PF00752.17 KNZ74865.1 - 0.028 14.9 0.0 0.086 13.3 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Barwin PF00967.17 KNZ74866.1 - 0.003 17.4 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Barwin family zinc_ribbon_2 PF13240.6 KNZ74866.1 - 0.4 10.5 4.2 25 4.7 0.5 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Cornichon PF03311.14 KNZ74867.1 - 1.1e-44 151.6 9.6 1.3e-44 151.4 9.6 1.1 1 0 0 1 1 1 1 Cornichon protein Cornichon PF03311.14 KNZ74868.1 - 1.3e-45 154.7 3.7 1.5e-45 154.4 3.7 1.1 1 0 0 1 1 1 1 Cornichon protein AMP-binding PF00501.28 KNZ74870.1 - 2.7e-70 237.1 0.0 1.2e-67 228.4 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ74870.1 - 1e-10 42.4 1.0 2.2e-10 41.3 0.2 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase_fungal PF17667.1 KNZ74871.1 - 7.8e-26 90.8 0.1 1.1e-25 90.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Tox-REase-9 PF15650.6 KNZ74871.1 - 0.083 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 9 RRM_1 PF00076.22 KNZ74872.1 - 3.7e-06 26.7 0.0 6.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KNZ74872.1 - 3.6 8.2 10.1 7 7.3 10.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Hydrophobin PF01185.18 KNZ74873.1 - 1.2e-15 57.8 11.9 1.5e-15 57.6 11.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.18 KNZ74874.1 - 6e-12 46.0 13.9 7.2e-12 45.8 13.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DAO PF01266.24 KNZ74875.1 - 1.1e-38 133.8 0.2 1.2e-38 133.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ74875.1 - 1.6e-05 24.3 0.0 0.0089 15.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ74875.1 - 6.6e-05 22.3 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ74875.1 - 0.00011 22.3 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KNZ74875.1 - 0.0003 21.3 0.0 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KNZ74875.1 - 0.0006 19.2 0.0 0.044 13.1 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 KNZ74875.1 - 0.0018 18.3 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KNZ74875.1 - 0.002 17.3 0.2 0.61 9.1 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KNZ74875.1 - 0.016 15.2 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KNZ74875.1 - 0.02 14.0 0.1 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KNZ74875.1 - 0.051 12.3 0.0 5.5 5.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KNZ74875.1 - 0.061 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KNZ74875.1 - 0.085 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Terminase_5 PF06056.12 KNZ74875.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Glyco_transf_49 PF13896.6 KNZ74876.1 - 5.6e-65 219.9 1.2 1.6e-53 182.2 0.2 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_4 PF13704.6 KNZ74876.1 - 0.1 13.1 0.1 0.34 11.5 0.1 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ank_4 PF13637.6 KNZ74877.1 - 0.00088 19.8 0.2 1.8 9.3 0.0 3.8 2 2 3 5 5 5 3 Ankyrin repeats (many copies) SAP PF02037.27 KNZ74877.1 - 0.0023 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain SWIB PF02201.18 KNZ74879.1 - 4.2e-27 93.8 0.0 7.9e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 KNZ74879.1 - 0.059 13.3 0.0 0.22 11.5 0.0 2.0 1 0 0 1 1 1 0 DEK C terminal domain Macoilin PF09726.9 KNZ74879.1 - 0.49 8.9 6.2 0.55 8.7 6.2 1.0 1 0 0 1 1 1 0 Macoilin family PBP1_TM PF14812.6 KNZ74879.1 - 0.58 10.6 19.1 0.46 10.9 6.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hid1 PF12722.7 KNZ74879.1 - 3.5 5.6 6.5 4.3 5.3 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sel1 PF08238.12 KNZ74880.1 - 9.7e-24 83.3 26.9 2.7e-05 24.7 0.1 9.3 9 1 0 9 9 9 6 Sel1 repeat TPR_16 PF13432.6 KNZ74880.1 - 0.0049 17.5 0.1 0.0049 17.5 0.1 4.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ74880.1 - 0.027 14.3 2.4 0.43 10.5 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74880.1 - 0.047 13.8 0.3 0.047 13.8 0.3 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ74880.1 - 0.26 12.2 3.3 1.2 10.2 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ74880.1 - 1.2 9.9 9.3 64 4.5 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPTA PF01239.22 KNZ74881.1 - 3.4e-08 33.0 7.6 0.00052 19.7 0.0 3.6 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat RNase_T PF00929.24 KNZ74882.1 - 3.9e-26 92.5 0.0 4.7e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 KNZ74882.1 - 2.2e-05 24.5 0.0 2.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Nucleoside_tran PF01733.18 KNZ74883.1 - 0.092 12.1 3.7 0.12 11.8 1.0 2.1 1 1 0 2 2 2 0 Nucleoside transporter MRAP PF15183.6 KNZ74883.1 - 0.13 12.2 0.8 17 5.5 0.6 2.7 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family CPSase_L_D2 PF02786.17 KNZ74884.1 - 5.9e-108 359.2 0.0 2.5e-83 278.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KNZ74884.1 - 4.4e-41 140.1 0.5 9.5e-41 139.0 0.5 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KNZ74884.1 - 1.8e-16 60.2 0.0 1.9e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KNZ74884.1 - 5e-13 49.1 0.0 8e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KNZ74884.1 - 1.1e-10 41.3 0.0 0.00057 19.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 KNZ74884.1 - 3e-06 26.9 0.0 0.0081 15.6 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KNZ74884.1 - 5.8e-05 23.2 0.0 0.0099 15.9 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KNZ74884.1 - 0.0025 17.4 0.0 2.6 7.6 0.0 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain Peptidase_M17_N PF02789.17 KNZ74884.1 - 0.16 11.8 0.1 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain 2-oxoacid_dh PF00198.23 KNZ74885.1 - 2.2e-82 276.0 0.1 2.7e-82 275.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KNZ74885.1 - 1.1e-14 54.0 2.4 2.2e-14 53.0 2.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 KNZ74885.1 - 1.9e-06 27.6 0.4 4e-05 23.3 0.3 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 KNZ74885.1 - 0.022 15.4 4.0 2.8 8.7 2.0 2.8 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 KNZ74885.1 - 0.052 13.4 2.3 0.068 13.1 0.4 2.0 1 1 1 2 2 2 0 Glycine cleavage H-protein RnfC_N PF13375.6 KNZ74885.1 - 0.073 13.0 1.0 0.33 10.9 0.7 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF228 PF02989.14 KNZ74885.1 - 0.11 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Lyase_aromatic PF00221.19 KNZ74886.1 - 6e-152 506.5 0.8 9.2e-152 505.9 0.8 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase ICAT PF06384.11 KNZ74886.1 - 0.06 13.6 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Fcf1 PF04900.12 KNZ74887.1 - 3.1e-37 126.9 2.5 3.1e-37 126.9 2.5 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 KNZ74887.1 - 1e-11 45.2 0.1 2.9e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 PIN like domain Imm-NTF2 PF15655.6 KNZ74887.1 - 0.069 13.4 0.5 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 NTF2 fold immunity protein DUF1917 PF08939.10 KNZ74888.1 - 3.3e-26 92.8 0.1 3.3e-26 92.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) UPF0029 PF01205.19 KNZ74890.1 - 1.7e-25 89.4 0.0 2.8e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Rer1 PF03248.13 KNZ74891.1 - 2.6e-73 245.4 1.9 3e-73 245.2 1.9 1.0 1 0 0 1 1 1 1 Rer1 family Torsin PF06309.11 KNZ74892.1 - 0.0049 17.0 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 Torsin KAP_NTPase PF07693.14 KNZ74892.1 - 0.0091 15.3 0.0 0.0096 15.2 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 KNZ74892.1 - 0.029 14.7 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KNZ74892.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KNZ74892.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 KNZ74892.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 KNZ74892.1 - 0.084 12.9 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KNZ74892.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KNZ74892.1 - 0.25 11.0 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase Acetyltransf_1 PF00583.25 KNZ74893.1 - 3.5e-09 36.9 0.0 5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KNZ74893.1 - 2.8e-05 24.0 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KNZ74893.1 - 6.6e-05 23.3 0.0 0.00016 22.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNZ74893.1 - 0.0013 19.5 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNZ74893.1 - 0.0036 17.4 0.0 0.0061 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KNZ74893.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cyclin_N PF00134.23 KNZ74894.1 - 1.5e-09 37.7 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KNZ74894.1 - 6.9e-06 26.5 0.2 2.3e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Cyclin DUF2457 PF10446.9 KNZ74894.1 - 9.2 5.3 12.1 12 4.9 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-CCCH_2 PF14608.6 KNZ74895.1 - 2.2e-15 56.4 28.6 1e-05 25.8 4.2 4.3 4 0 0 4 4 4 4 RNA-binding, Nab2-type zinc finger AAA_16 PF13191.6 KNZ74896.1 - 3.1e-06 27.7 0.2 1e-05 26.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KNZ74896.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KNZ74896.1 - 0.13 12.0 0.0 0.41 10.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RSN1_7TM PF02714.15 KNZ74897.1 - 4.2e-50 170.6 27.1 1.7e-49 168.6 15.1 2.9 2 1 1 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KNZ74897.1 - 1.6e-37 129.5 0.0 2.3e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KNZ74897.1 - 7.1e-36 123.3 0.2 7.1e-36 123.3 0.2 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RNA_pol_Rpb1_R PF05001.13 KNZ74897.1 - 0.3 11.5 2.2 1.3 9.5 2.2 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb1 C-terminal repeat Tim17 PF02466.19 KNZ74898.1 - 1.4e-30 105.9 8.3 2.2e-30 105.3 8.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Arrestin_C PF02752.22 KNZ74899.1 - 3e-12 47.1 0.1 1.8e-11 44.6 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KNZ74899.1 - 8.1e-10 38.9 0.0 2.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 KNZ74899.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like Amidohydro_1 PF01979.20 KNZ74902.1 - 2e-24 86.6 0.0 2.7e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KNZ74902.1 - 1.4e-10 41.2 0.0 6.9e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family MFS_1 PF07690.16 KNZ74904.1 - 1.2e-36 126.3 32.4 1.6e-36 125.9 32.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily GPR15L PF15854.5 KNZ74904.1 - 0.07 13.4 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Peptidase_U4 PF03419.13 KNZ74904.1 - 2.9 7.1 21.8 0.012 14.9 8.5 2.3 2 1 0 2 2 2 0 Sporulation factor SpoIIGA MFS_1 PF07690.16 KNZ74905.1 - 3.7e-37 128.1 60.3 6.1e-34 117.5 36.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CTP_transf_like PF01467.26 KNZ74906.1 - 1e-23 84.1 0.0 1.3e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DNA_pol_B_thumb PF14791.6 KNZ74907.1 - 5.5e-20 71.3 0.2 1.4e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KNZ74907.1 - 1.7e-16 60.4 0.0 3.9e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 KNZ74907.1 - 2.2e-07 30.6 0.0 5.3e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 KNZ74907.1 - 0.032 14.5 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus HHH_5 PF14520.6 KNZ74907.1 - 0.057 14.0 0.0 0.22 12.2 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain Acyl-CoA_dh_1 PF00441.24 KNZ74908.1 - 6.8e-26 91.3 0.2 1.1e-25 90.7 0.1 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KNZ74908.1 - 3.8e-19 68.7 0.0 7.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KNZ74908.1 - 5.8e-19 68.8 0.0 1.1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KNZ74908.1 - 0.00045 20.5 0.1 0.0077 16.5 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KNZ74908.1 - 0.23 11.1 0.0 0.56 9.8 0.0 1.6 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Ribosomal_L35Ae PF01247.18 KNZ74909.1 - 2.9e-44 149.2 0.3 3.2e-44 149.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KNZ74909.1 - 0.0051 17.0 0.1 1.4 9.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain CDK5_activator PF03261.15 KNZ74910.1 - 1 8.9 6.5 1.5 8.2 6.5 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FLILHELTA PF10306.9 KNZ74911.1 - 2.7e-08 34.1 0.0 5.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA PIEZO PF15917.5 KNZ74912.1 - 2.9 7.3 17.0 0.84 9.1 4.2 2.3 2 0 0 2 2 2 0 Piezo NAD_binding_4 PF07993.12 KNZ74913.1 - 1.1e-26 93.6 0.0 1.6e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ74913.1 - 1.1e-25 90.1 0.0 1.8e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KNZ74913.1 - 2.6e-05 23.8 0.0 6.4e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ74913.1 - 0.0085 16.0 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding PP-binding PF00550.25 KNZ74913.1 - 0.025 14.9 0.6 0.093 13.1 0.2 2.3 2 1 0 2 2 2 0 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 KNZ74913.1 - 0.099 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkH PF02386.16 KNZ74914.1 - 9.8e-98 327.8 10.2 1.2e-96 324.2 3.7 2.1 2 0 0 2 2 2 2 Cation transport protein Isy1 PF06246.12 KNZ74915.1 - 3.7e-87 292.1 1.0 4.3e-87 291.9 1.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family OEP PF02321.18 KNZ74916.1 - 0.00022 21.1 1.8 0.00046 20.1 1.8 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein Peptidase_S64 PF08192.11 KNZ74916.1 - 0.0024 16.5 0.0 0.0059 15.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.13 KNZ74916.1 - 0.0044 16.3 0.8 0.0071 15.6 0.1 1.6 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 SAS4 PF15460.6 KNZ74916.1 - 0.016 15.3 1.0 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 SH3BGR PF04908.15 KNZ74916.1 - 0.14 12.4 0.1 0.94 9.7 0.1 2.1 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein MIF4G PF02854.19 KNZ74917.1 - 3.3e-53 180.5 1.4 4.3e-53 180.1 0.6 1.6 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 KNZ74917.1 - 1e-09 38.3 0.3 1.5e-08 34.6 0.1 2.4 2 0 0 2 2 2 1 MA3 domain Ribosomal_60s PF00428.19 KNZ74917.1 - 2.9 8.5 16.9 0.63 10.7 3.2 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein LCM PF04072.14 KNZ74918.1 - 1.5e-05 25.0 0.2 1.8e-05 24.8 0.2 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Helitron_like_N PF14214.6 KNZ74919.1 - 5.7e-26 91.9 0.0 6.9e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ74919.1 - 0.19 11.7 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Inovirus Gp2 MitMem_reg PF13012.6 KNZ74920.1 - 0.034 14.5 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ74921.1 - 1.4e-102 343.6 0.0 1.6e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74921.1 - 7.4e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain 4HPAD_g_N PF18671.1 KNZ74921.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Viral_helicase1 PF01443.18 KNZ74921.1 - 0.056 13.2 0.2 0.12 12.1 0.2 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.14 KNZ74922.1 - 1.2e-06 26.8 0.1 1.2e-06 26.8 0.1 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ74922.1 - 0.024 14.5 0.1 0.054 13.3 0.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PEP_mutase PF13714.6 KNZ74923.1 - 4.7e-42 144.1 4.8 6.2e-42 143.7 4.8 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KNZ74923.1 - 2.8e-19 69.0 0.8 3.9e-19 68.6 0.8 1.1 1 0 0 1 1 1 1 Isocitrate lyase family FMN_dh PF01070.18 KNZ74924.1 - 5.7e-117 390.6 0.1 6.9e-117 390.4 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KNZ74924.1 - 2.8e-21 75.5 0.0 6.4e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KNZ74924.1 - 0.00016 20.9 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KNZ74924.1 - 0.0023 17.0 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Hexapep PF00132.24 KNZ74926.1 - 2.9e-10 39.4 20.2 2.1e-07 30.4 2.1 4.5 4 1 1 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KNZ74926.1 - 2.5e-05 23.9 13.0 0.00072 19.3 0.6 3.9 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KNZ74926.1 - 0.00022 20.3 0.0 0.00032 19.8 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase Chitin_synth_1 PF01644.17 KNZ74927.1 - 6.2e-75 250.6 0.0 1e-74 250.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 KNZ74927.1 - 1.2e-19 70.4 0.9 2.3e-17 62.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 KNZ74927.1 - 3.7e-18 65.3 0.2 1.2e-17 63.6 0.2 1.9 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 KNZ74927.1 - 4.8e-05 23.3 7.6 0.00085 19.3 7.6 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 R3H-assoc PF13902.6 KNZ74928.1 - 0.041 14.3 0.8 0.09 13.2 0.1 1.8 2 0 0 2 2 2 0 R3H-associated N-terminal domain HSP70 PF00012.20 KNZ74929.1 - 9.2e-233 773.8 8.5 1.1e-232 773.5 8.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNZ74929.1 - 7.1e-14 51.4 1.4 7.1e-14 51.4 1.4 2.3 3 0 0 3 3 3 1 MreB/Mbl protein DMRL_synthase PF00885.19 KNZ74929.1 - 0.091 12.6 0.2 0.43 10.4 0.1 2.0 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase Abhydrolase_3 PF07859.13 KNZ74930.1 - 5e-39 134.4 0.0 2e-32 112.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold APH PF01636.23 KNZ74930.1 - 3.8e-36 125.2 0.0 9.2e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Say1_Mug180 PF10340.9 KNZ74930.1 - 5.5e-08 32.1 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Choline_kinase PF01633.20 KNZ74930.1 - 4.8e-05 23.1 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 KNZ74930.1 - 0.0043 16.4 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase DUF2053 PF09767.9 KNZ74930.1 - 0.028 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) TPR_1 PF00515.28 KNZ74931.1 - 1.3e-22 78.6 16.7 1.6e-05 24.5 0.1 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ74931.1 - 4.6e-22 78.3 17.2 0.0006 20.3 0.0 9.4 8 2 2 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74931.1 - 2.1e-19 68.0 39.1 0.00028 20.7 0.0 13.3 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ74931.1 - 7.5e-19 67.8 22.9 6.3e-06 26.4 2.2 8.7 5 2 3 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ74931.1 - 1.5e-17 62.3 10.2 0.0058 16.8 0.0 10.5 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ74931.1 - 1.9e-14 53.2 20.3 4.7e-05 23.8 0.1 10.2 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74931.1 - 5.2e-14 52.6 24.0 0.00048 20.7 0.4 9.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ74931.1 - 5.9e-12 45.3 30.9 0.064 14.1 0.1 12.8 9 3 5 14 14 14 3 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ74931.1 - 1.6e-09 37.1 14.8 0.1 12.6 0.1 8.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ74931.1 - 5.7e-09 35.6 29.3 0.016 15.1 0.2 9.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ74931.1 - 1.6e-08 34.3 4.5 7.1 7.3 0.0 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ74931.1 - 1.4e-06 28.4 12.0 0.091 13.0 0.3 5.5 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 KNZ74931.1 - 0.00023 20.8 0.7 2.9 7.6 0.0 6.4 8 0 0 8 8 8 1 TPR repeat DUF2989 PF11207.8 KNZ74931.1 - 0.00051 19.9 0.8 0.77 9.5 0.0 4.8 3 2 2 5 5 5 1 Protein of unknown function (DUF2989) PknG_TPR PF16918.5 KNZ74931.1 - 0.0042 15.9 0.2 0.0042 15.9 0.2 3.8 4 0 0 4 4 4 1 Protein kinase G tetratricopeptide repeat TPR_4 PF07721.14 KNZ74931.1 - 5.7 7.9 18.3 4.7 8.1 0.2 7.3 9 0 0 9 9 5 0 Tetratricopeptide repeat Ribosomal_S2 PF00318.20 KNZ74932.1 - 1.6e-29 102.7 0.1 2.5e-14 53.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KNZ74932.1 - 5.6e-10 40.4 7.1 1.1e-09 39.6 7.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus SPA PF08616.10 KNZ74933.1 - 7.1e-34 116.2 0.0 2.2e-33 114.6 0.0 1.9 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 KNZ74933.1 - 6.6e-18 65.5 0.3 1.2e-13 51.7 0.2 2.7 3 0 0 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 KNZ74933.1 - 0.02 13.6 0.0 1.5 7.4 0.0 3.1 2 1 0 2 2 2 0 Transport protein Avl9 Fungal_trans PF04082.18 KNZ74934.1 - 1.7e-10 40.4 0.0 2.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ74934.1 - 0.0088 16.1 4.1 0.02 15.0 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MerR-DNA-bind PF09278.11 KNZ74934.1 - 0.079 13.5 1.0 0.23 12.0 0.1 2.2 2 0 0 2 2 2 0 MerR, DNA binding Copper-fist PF00649.18 KNZ74934.1 - 0.3 10.6 2.9 0.71 9.4 2.9 1.6 1 0 0 1 1 1 0 Copper fist DNA binding domain Peptidase_C50 PF03568.17 KNZ74935.1 - 1.5e-133 445.8 0.0 3.1e-133 444.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 KNZ74935.1 - 1.1e-07 32.1 27.5 0.034 14.4 1.0 8.0 8 1 0 9 9 8 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ74935.1 - 0.00016 21.2 8.2 0.0014 18.1 1.6 3.5 3 1 1 4 4 4 2 MalT-like TPR region CHAT PF12770.7 KNZ74935.1 - 0.0006 19.3 0.1 0.1 12.0 0.0 2.8 2 0 0 2 2 2 1 CHAT domain SPO22 PF08631.10 KNZ74935.1 - 0.0028 17.2 1.6 2.6 7.5 0.2 3.9 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KNZ74935.1 - 0.063 13.5 2.7 64 3.9 0.1 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 KNZ74935.1 - 0.094 12.6 13.5 0.29 11.0 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat HBD PF18534.1 KNZ74935.1 - 0.17 12.0 1.0 0.54 10.4 0.1 2.3 2 0 0 2 2 2 0 Helical bundle domain TPR_8 PF13181.6 KNZ74935.1 - 0.3 11.4 13.8 1.3 9.4 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ74935.1 - 0.61 10.3 22.9 1.8 8.9 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ74935.1 - 0.88 10.3 5.3 7 7.5 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0137 PF03677.13 KNZ74936.1 - 0.011 15.5 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Retrotrans_gag PF03732.17 KNZ74936.1 - 0.13 12.6 0.7 0.19 12.1 0.7 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein PIF1 PF05970.14 KNZ74937.1 - 3.6e-55 187.6 0.1 4.5e-55 187.3 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ74937.1 - 1.8e-06 27.8 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ74937.1 - 0.0012 19.3 0.0 0.0015 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ74937.1 - 0.0028 17.7 0.0 0.015 15.3 0.0 1.8 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ74937.1 - 0.016 14.9 0.1 0.035 13.8 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.8 KNZ74937.1 - 0.042 12.7 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.22 KNZ74937.1 - 0.046 14.1 0.2 0.24 11.8 0.1 2.2 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 KNZ74937.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ74937.1 - 0.076 12.6 0.1 0.097 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ74937.1 - 0.12 12.8 0.2 1.3 9.5 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.14 KNZ74938.1 - 1.8e-06 26.2 0.0 1.9e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ74938.1 - 0.0061 16.4 0.1 0.017 14.9 0.1 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Inos-1-P_synth PF01658.17 KNZ74939.1 - 0.00073 19.8 0.0 0.00082 19.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DHH PF01368.20 KNZ74940.1 - 0.0023 18.1 0.1 0.01 16.0 0.1 1.9 1 1 1 2 2 2 1 DHH family VWA_CoxE PF05762.14 KNZ74940.1 - 0.011 15.1 0.2 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Terpene_synth_C PF03936.16 KNZ74941.1 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Pkinase_Tyr PF07714.17 KNZ74942.1 - 1.4e-38 132.6 0.0 1.9e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ74942.1 - 1.8e-33 116.0 0.0 3.4e-33 115.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ74942.1 - 0.0027 17.7 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RT_RNaseH PF17917.1 KNZ74945.1 - 3.4e-23 81.9 0.1 1.1e-22 80.3 0.1 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Peptidase_S8 PF00082.22 KNZ74945.1 - 6.6e-20 71.6 8.7 9.5e-20 71.0 8.7 1.3 1 0 0 1 1 1 1 Subtilase family RT_RNaseH_2 PF17919.1 KNZ74945.1 - 1.1e-12 47.8 0.0 2.3e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Inhibitor_I9 PF05922.16 KNZ74945.1 - 2.2e-06 28.2 0.0 4.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 RVT_3 PF13456.6 KNZ74945.1 - 0.083 12.7 0.9 0.19 11.5 0.1 2.1 2 0 0 2 2 2 0 Reverse transcriptase-like Peroxidase_2 PF01328.17 KNZ74946.1 - 6.1e-49 167.1 0.0 7.5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 NotI PF12183.8 KNZ74946.1 - 0.14 11.4 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease NotI MFS_1 PF07690.16 KNZ74947.1 - 1.3e-36 126.2 26.6 1.3e-36 126.2 26.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 KNZ74947.1 - 0.019 14.9 3.6 0.019 14.9 3.6 2.9 3 1 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF5392 PF17370.2 KNZ74947.1 - 2.5 8.2 5.5 19 5.4 1.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5392) Amidohydro_1 PF01979.20 KNZ74948.1 - 1e-05 25.0 0.1 0.00014 21.3 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Radical_SAM PF04055.21 KNZ74948.1 - 0.045 14.1 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Radical SAM superfamily Amidohydro_3 PF07969.11 KNZ74948.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family MatE PF01554.18 KNZ74949.1 - 8.4e-27 93.8 17.0 4.2e-22 78.5 7.1 3.5 2 1 1 3 3 3 3 MatE SHR3_chaperone PF08229.11 KNZ74949.1 - 0.091 11.7 0.1 0.22 10.5 0.1 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 ZapB PF06005.12 KNZ74950.1 - 2 8.9 7.3 0.29 11.6 3.0 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Mito_carr PF00153.27 KNZ74953.1 - 3.1e-22 78.3 8.2 1.6e-10 40.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2456 PF10445.9 KNZ74953.1 - 0.089 12.9 3.5 0.42 10.7 0.0 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF2456) DUF1899 PF08953.11 KNZ74954.1 - 6.8e-29 99.6 0.1 1.5e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 KNZ74954.1 - 1.1e-18 67.3 3.1 2.2e-05 25.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_4 PF16300.5 KNZ74954.1 - 5.9e-18 64.5 0.5 1.2e-17 63.5 0.5 1.6 1 0 0 1 1 1 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 KNZ74954.1 - 3e-05 24.2 0.0 0.025 14.9 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ74954.1 - 0.033 14.1 0.0 4.2 7.2 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 KNZ74954.1 - 0.089 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Spc42p PF11544.8 KNZ74954.1 - 0.17 11.9 0.6 0.3 11.1 0.6 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p ApoLp-III PF07464.11 KNZ74954.1 - 0.21 11.7 0.7 0.31 11.1 0.7 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DRMBL PF07522.14 KNZ74955.1 - 1.4e-10 41.3 0.1 1.8e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 KNZ74955.1 - 0.003 17.1 0.6 0.014 14.9 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 KNZ74955.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain zf-MYND PF01753.18 KNZ74956.1 - 2.8e-11 43.3 13.0 2.8e-11 43.3 13.0 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 KNZ74956.1 - 0.0076 16.3 0.8 0.019 15.1 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 KNZ74956.1 - 0.064 13.6 9.5 0.14 12.5 9.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pyr_redox_2 PF07992.14 KNZ74957.1 - 4e-29 101.8 0.0 4.9e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ74957.1 - 5.8e-12 46.0 0.9 8.4e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ74957.1 - 0.00012 21.3 0.0 2.3 7.2 0.1 3.2 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 KNZ74957.1 - 0.00016 21.7 0.1 0.64 10.0 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KNZ74957.1 - 0.00042 20.0 3.7 0.11 12.0 0.1 3.3 2 1 1 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KNZ74957.1 - 0.0016 17.4 1.0 0.01 14.7 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 KNZ74957.1 - 0.0022 17.3 0.2 0.12 11.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KNZ74957.1 - 0.0027 17.0 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KNZ74957.1 - 0.0087 16.5 0.3 7.2 7.1 0.0 2.9 3 0 0 3 3 3 2 Putative NAD(P)-binding TrkA_N PF02254.18 KNZ74957.1 - 0.011 16.0 0.1 3.6 7.9 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 KNZ74957.1 - 0.015 14.4 0.4 2.9 6.9 0.0 3.1 2 1 0 3 3 3 0 Glucose inhibited division protein A K_oxygenase PF13434.6 KNZ74957.1 - 0.08 12.1 0.0 9.9 5.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 KNZ74958.1 - 4.5e-54 183.8 0.0 5.9e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ74958.1 - 1.7e-31 109.7 0.0 3.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ74958.1 - 0.00029 21.0 0.8 0.00075 19.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ74958.1 - 0.0031 16.6 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KNZ74958.1 - 0.0077 15.9 0.4 0.013 15.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ74958.1 - 0.02 14.0 1.0 0.037 13.1 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KNZ74958.1 - 0.023 14.0 0.0 0.067 12.4 0.0 1.7 2 0 0 2 2 2 0 Thi4 family dCMP_cyt_deam_1 PF00383.23 KNZ74959.1 - 4.8e-17 61.7 0.1 6.1e-17 61.4 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 KNZ74959.1 - 1.3e-13 51.3 1.7 1.6e-10 41.3 0.2 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 KNZ74959.1 - 0.0003 20.4 1.2 0.15 11.6 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases p450 PF00067.22 KNZ74960.1 - 3.1e-61 207.6 0.0 3.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KNZ74960.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Sortilin-Vps10 PF15902.5 KNZ74961.1 - 2.6e-165 550.6 0.0 4.5e-144 480.6 0.0 2.5 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KNZ74961.1 - 1.1e-71 240.6 13.4 3.1e-40 138.3 1.2 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KNZ74961.1 - 4e-08 32.1 33.3 0.51 10.6 0.1 8.8 8 0 0 8 8 8 5 BNR/Asp-box repeat PSII_BNR PF14870.6 KNZ74961.1 - 0.0035 16.6 2.8 0.87 8.8 0.0 3.8 3 2 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 preSET_CXC PF18264.1 KNZ74961.1 - 3.8 8.1 9.3 19 5.9 2.3 2.8 2 0 0 2 2 2 0 CXC domain p450 PF00067.22 KNZ74962.1 - 8e-68 229.3 0.0 9.7e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hira PF07569.11 KNZ74962.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split p450 PF00067.22 KNZ74963.1 - 2.6e-19 69.3 0.0 3e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_N PF09825.9 KNZ74964.1 - 7.1e-51 173.4 0.0 9.3e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KNZ74964.1 - 2.6e-26 92.1 0.0 4.4e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.11 KNZ74964.1 - 0.0066 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose utilisation F-box PF00646.33 KNZ74965.1 - 0.0011 18.8 0.6 0.0025 17.6 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ74965.1 - 0.072 13.0 0.5 0.19 11.7 0.5 1.7 1 0 0 1 1 1 0 F-box-like Lipase_3 PF01764.25 KNZ74967.1 - 2.3e-21 76.2 0.0 3e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KNZ74967.1 - 0.0043 17.7 0.2 0.0051 17.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KNZ74967.1 - 0.019 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 KNZ74967.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 KNZ74967.1 - 0.033 13.7 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Pro_CA PF00484.19 KNZ74967.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Carbonic anhydrase TPR_1 PF00515.28 KNZ74968.1 - 2.5e-24 84.0 6.8 0.0001 22.0 0.1 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat DnaJ PF00226.31 KNZ74968.1 - 6.2e-23 80.7 0.4 1.2e-22 79.8 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 KNZ74968.1 - 4.2e-20 70.2 21.1 0.00017 21.4 0.1 8.6 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ74968.1 - 5.1e-16 58.1 5.4 1.9e-05 24.2 0.7 5.6 4 1 1 5 5 5 4 TPR repeat TPR_9 PF13371.6 KNZ74968.1 - 1.1e-14 54.3 8.8 1.4e-06 28.3 0.3 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ74968.1 - 1.5e-11 44.8 22.9 0.016 15.9 0.9 6.4 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ74968.1 - 3.9e-09 36.7 18.4 0.016 15.4 0.2 6.5 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ74968.1 - 1.1e-07 31.5 5.2 0.092 13.0 0.1 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ74968.1 - 3.6e-07 30.3 3.8 0.09 13.0 0.1 4.9 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KNZ74968.1 - 5.1e-06 26.9 17.5 0.27 12.2 0.0 7.7 4 3 5 9 9 9 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 KNZ74968.1 - 8.4e-06 25.1 1.4 1 8.9 0.0 4.6 4 0 0 4 4 4 1 SHNi-TPR MIT PF04212.18 KNZ74968.1 - 2.4e-05 24.3 3.2 0.35 11.0 0.0 4.8 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 KNZ74968.1 - 4.1e-05 24.0 20.0 0.66 10.5 1.0 6.2 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ74968.1 - 0.0047 16.9 5.3 0.89 9.7 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ74968.1 - 0.0064 16.8 3.1 17 6.1 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ74968.1 - 0.021 14.7 3.7 13 5.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPM_phosphatase PF04536.14 KNZ74968.1 - 0.044 13.9 0.4 9.1 6.5 0.0 2.9 3 0 0 3 3 2 0 TPM domain Surfac_D-trimer PF09006.11 KNZ74968.1 - 0.22 11.4 0.6 0.65 9.9 0.2 2.0 2 0 0 2 2 1 0 Lung surfactant protein D coiled-coil trimerisation Fis1_TPR_C PF14853.6 KNZ74968.1 - 0.34 11.0 3.5 19 5.4 0.0 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 KNZ74968.1 - 3.3 8.5 11.6 27 5.7 0.1 5.9 7 1 1 8 8 6 0 Tetratricopeptide repeat WD40 PF00400.32 KNZ74970.1 - 9.9e-38 127.5 25.0 8.4e-07 29.6 0.2 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ74970.1 - 2.3e-11 43.9 0.4 0.0081 16.4 0.0 5.9 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ74970.1 - 1.6e-06 27.6 0.0 0.015 14.6 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 KNZ74970.1 - 0.00068 18.4 6.1 4.3 5.9 0.0 4.7 3 1 2 5 5 5 3 Nucleoporin Nup120/160 DUF1513 PF07433.11 KNZ74970.1 - 0.011 14.8 0.0 1.5 7.8 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) PALB2_WD40 PF16756.5 KNZ74970.1 - 1.1 8.0 4.2 5.5 5.8 0.2 3.1 1 1 2 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KNZ74970.1 - 9.6 6.8 8.6 54 4.5 0.3 4.9 8 0 0 8 8 8 0 PQQ-like domain PAAR_motif PF05488.13 KNZ74971.1 - 0.029 14.5 0.2 0.056 13.6 0.2 1.4 1 0 0 1 1 1 0 PAAR motif Mito_carr PF00153.27 KNZ74972.1 - 2.9e-65 216.2 4.5 1.5e-23 82.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HP_OMP PF01856.17 KNZ74972.1 - 0.033 14.3 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 Helicobacter outer membrane protein HMD PF03201.16 KNZ74972.1 - 0.38 11.0 2.8 1 9.6 0.0 2.6 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase RNA_pol_Rbc25 PF08292.12 KNZ74973.1 - 5.8e-32 110.6 0.0 9.4e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KNZ74973.1 - 5.6e-21 74.7 1.5 6.6e-21 74.5 0.1 1.9 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Trehalase PF01204.18 KNZ74974.1 - 5.5e-98 329.0 6.4 1.1e-94 318.2 0.2 3.2 2 2 0 2 2 2 2 Trehalase GDE_C PF06202.14 KNZ74974.1 - 0.047 12.6 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Aminotran_5 PF00266.19 KNZ74976.1 - 2.6e-15 56.3 0.0 4.2e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KNZ74976.1 - 2e-10 40.4 0.0 2.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNZ74976.1 - 0.0027 17.1 0.1 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Sod_Fe_C PF02777.18 KNZ74977.1 - 3.8e-35 120.1 0.0 7.8e-35 119.1 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KNZ74977.1 - 2.2e-31 108.2 3.2 4.3e-31 107.2 2.1 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain PMI_typeI PF01238.21 KNZ74978.1 - 1.4e-14 54.1 0.1 3.1e-14 53.0 0.1 1.5 1 1 0 1 1 1 1 Phosphomannose isomerase type I zf-HC5HC2H_2 PF13832.6 KNZ74979.1 - 3.7e-31 107.5 12.7 3e-30 104.6 8.4 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 KNZ74979.1 - 1.6e-23 83.8 0.5 1.6e-23 83.8 0.5 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 KNZ74979.1 - 2.2e-23 82.3 10.6 2e-22 79.2 5.6 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain Bromodomain PF00439.25 KNZ74979.1 - 2.5e-19 69.1 0.0 5e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.6 KNZ74979.1 - 1e-14 53.8 3.0 1e-14 53.8 3.0 3.4 3 1 1 4 4 4 1 PHD-finger PWWP PF00855.17 KNZ74979.1 - 3.4e-14 53.0 0.6 8.4e-14 51.8 0.6 1.7 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 KNZ74979.1 - 1.8e-10 40.5 5.9 1.8e-10 40.5 5.9 3.1 3 0 0 3 3 3 1 PHD-finger C1_1 PF00130.22 KNZ74979.1 - 0.0055 16.6 0.6 0.0055 16.6 0.6 2.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1525 PF07511.11 KNZ74979.1 - 0.25 11.5 1.0 3.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1525) zf-PHD-like PF15446.6 KNZ74979.1 - 1.2 8.8 14.7 0.022 14.4 4.4 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain FYVE_2 PF02318.16 KNZ74979.1 - 6 7.1 9.5 0.1 12.8 0.5 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4890 PF16231.5 KNZ74979.1 - 7.6 7.1 9.1 18 5.8 0.2 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4890) C1_2 PF03107.16 KNZ74979.1 - 9.6 6.6 19.2 0.23 11.8 1.5 3.0 3 0 0 3 3 3 0 C1 domain PMI_typeI PF01238.21 KNZ74980.1 - 9.3e-115 383.8 0.0 1.1e-114 383.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KNZ74980.1 - 0.0012 18.5 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KNZ74980.1 - 0.01 15.8 0.0 5.5 6.9 0.0 2.6 3 0 0 3 3 3 0 AraC-like ligand binding domain Thioredoxin PF00085.20 KNZ74981.1 - 4.9e-20 71.4 0.1 1.7e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 KNZ74981.1 - 0.00019 21.9 0.0 0.0012 19.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KNZ74981.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 KNZ74981.1 - 0.18 12.2 0.0 13 6.2 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Glyco_hydro_3_C PF01915.22 KNZ74982.1 - 3.1e-57 193.8 0.0 6.4e-57 192.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ74982.1 - 8.9e-46 156.7 0.0 1.5e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ74982.1 - 1.4e-20 73.2 0.5 2.8e-20 72.2 0.5 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KNZ74982.1 - 1.5e-12 47.5 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain ADH_zinc_N PF00107.26 KNZ74983.1 - 6.4e-28 97.3 0.9 1e-27 96.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ74983.1 - 3.7e-19 70.1 0.0 8e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ74983.1 - 2.7e-12 46.5 0.1 6.5e-12 45.3 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 KNZ74983.1 - 0.013 14.8 0.2 0.029 13.7 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 KNZ74983.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Melibiase_2 PF16499.5 KNZ74985.1 - 2.2e-45 155.0 0.9 3.2e-45 154.5 0.9 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KNZ74985.1 - 3.6e-15 55.8 0.2 6.4e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KNZ74985.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase Ran_BP1 PF00638.18 KNZ74986.1 - 0.00049 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 RanBP1 domain GPI-anchored PF10342.9 KNZ74987.1 - 1.2e-06 29.2 0.9 1.8e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RNase_H2_suC PF08615.11 KNZ74988.1 - 5.4e-17 62.3 0.6 9.7e-17 61.5 0.6 1.4 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Dynamin_M PF01031.20 KNZ74989.1 - 3e-107 358.1 0.1 7e-107 356.9 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KNZ74989.1 - 6.4e-55 185.8 0.2 2.2e-54 184.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KNZ74989.1 - 9.7e-30 102.6 2.4 2.8e-29 101.1 1.3 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KNZ74989.1 - 0.0001 22.4 0.1 0.00088 19.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 KNZ74989.1 - 0.043 13.1 0.0 7.4 5.8 0.0 2.4 2 0 0 2 2 2 0 AIG1 family AAA_15 PF13175.6 KNZ74989.1 - 0.049 13.3 0.4 8 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain TipAS PF07739.13 KNZ74989.1 - 0.1 13.1 0.0 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Adeno_E3_14_5 PF04834.12 KNZ74989.1 - 3.4 8.3 4.5 1.7 9.2 0.7 2.3 3 0 0 3 3 3 0 Early E3 14.5 kDa protein BCS1_N PF08740.11 KNZ74990.1 - 1.6e-44 152.1 1.8 1.6e-44 152.1 1.8 2.9 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KNZ74990.1 - 3.2e-15 56.7 0.0 4.8e-14 52.9 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ74990.1 - 0.0018 18.7 0.2 0.0018 18.7 0.2 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KNZ74990.1 - 0.0034 17.6 0.0 0.0034 17.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 KNZ74990.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KNZ74990.1 - 0.081 12.8 0.1 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 NACHT domain YlbE PF14003.6 KNZ74990.1 - 0.081 13.4 0.1 0.081 13.4 0.1 2.2 2 0 0 2 2 2 0 YlbE-like protein RuvB_N PF05496.12 KNZ74990.1 - 0.084 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Antimicrobial_2 PF08023.12 KNZ74990.1 - 0.42 11.2 1.3 0.96 10.0 0.2 2.1 2 0 0 2 2 2 0 Frog antimicrobial peptide DUF3492 PF11997.8 KNZ74990.1 - 8.2 6.1 8.6 19 4.9 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) SYS1 PF09801.9 KNZ74991.1 - 3.5e-25 88.9 2.7 4.4e-17 62.6 1.8 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network DPPIV_N PF00930.21 KNZ74992.1 - 1.7e-91 306.6 0.3 2.4e-91 306.2 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KNZ74992.1 - 2.7e-38 131.6 3.0 3.1e-18 66.0 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KNZ74992.1 - 0.00018 21.2 0.3 0.00052 19.7 0.1 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 KNZ74992.1 - 0.001 18.8 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold CSD2 PF17876.1 KNZ74992.1 - 0.0038 17.3 0.1 0.0093 16.1 0.1 1.6 1 0 0 1 1 1 1 Cold shock domain Abhydrolase_6 PF12697.7 KNZ74992.1 - 0.0057 17.3 0.0 0.016 15.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 KNZ74992.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KNZ74992.1 - 0.055 13.3 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 KNZ74992.1 - 0.055 13.0 0.7 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Nro1 PF12753.7 KNZ74993.1 - 0.016 14.2 0.2 0.57 9.1 0.1 2.1 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 Mito_carr PF00153.27 KNZ74994.1 - 3.3e-49 164.8 8.3 2.4e-21 75.4 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein HTH_28 PF13518.6 KNZ74994.1 - 0.02 15.0 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SnoaL_2 PF12680.7 KNZ74995.1 - 5.1e-10 39.9 0.0 6.2e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 KNZ74995.1 - 9e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.6 KNZ74995.1 - 0.01 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Polysacc_deac_1 PF01522.21 KNZ74996.1 - 2.7e-11 43.4 0.0 5.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KNZ74996.1 - 0.0044 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 KNZ74996.1 - 0.008 14.6 0.0 0.012 14.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2194) STT3 PF02516.14 KNZ74997.1 - 1.8e-144 482.3 36.6 9.7e-144 479.9 36.6 1.8 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Herpes_Helicase PF02689.14 KNZ74998.1 - 2.6e-06 25.7 0.0 2.8e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ74998.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Polysacc_deac_1 PF01522.21 KNZ74999.1 - 2.6e-12 46.7 0.0 5.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 KNZ74999.1 - 0.0078 15.9 0.1 0.018 14.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Plavaka PF18759.1 KNZ75003.1 - 0.00031 20.1 0.1 0.00045 19.6 0.1 1.2 1 0 0 1 1 1 1 Plavaka transposase PH PF00169.29 KNZ75004.1 - 0.0061 17.1 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 2 PH domain RNase_H PF00075.24 KNZ75009.1 - 1e-08 35.4 0.0 1.5e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 RNase H THRAP3_BCLAF1 PF15440.6 KNZ75009.1 - 0.0085 15.2 0.6 0.01 14.9 0.6 1.1 1 0 0 1 1 1 1 THRAP3/BCLAF1 family zf-CSL PF05207.13 KNZ75010.1 - 0.034 13.9 0.5 0.082 12.7 0.5 1.6 1 0 0 1 1 1 0 CSL zinc finger PIF1 PF05970.14 KNZ75011.1 - 5.3e-34 118.0 0.0 6.8e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KNZ75011.1 - 1.9e-06 26.2 0.0 2.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ75011.1 - 0.00032 20.4 0.0 0.00066 19.4 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain 4HPAD_g_N PF18671.1 KNZ75011.1 - 0.0055 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Mating_C PF12737.7 KNZ75013.1 - 1.2e-34 120.3 12.7 2.3e-34 119.4 12.7 1.4 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.11 KNZ75013.1 - 4.9e-11 42.3 0.4 1.4e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 KNZ75013.1 - 0.009 15.8 0.2 0.15 11.9 0.0 2.9 3 0 0 3 3 3 1 Homeodomain Homeodomain PF00046.29 KNZ75014.1 - 2.7e-14 52.7 0.3 5.7e-14 51.7 0.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KNZ75014.1 - 1.5e-06 28.0 0.2 4.6e-06 26.4 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Apolipoprotein PF01442.18 KNZ75015.1 - 1.5 8.7 11.7 12 5.7 11.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 KNZ75015.1 - 4.9 7.8 9.3 52 4.5 1.8 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Glyco_transf_8 PF01501.20 KNZ75016.1 - 1.5e-20 73.9 0.0 1.3e-19 70.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KNZ75016.1 - 0.027 13.8 0.1 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative ABC1 PF03109.16 KNZ75017.1 - 8.1e-22 77.6 0.0 5.6e-12 45.9 0.0 2.6 2 0 0 2 2 2 2 ABC1 family HORMA PF02301.18 KNZ75018.1 - 8.2e-10 38.6 0.0 1.6e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 HORMA domain MFS_1 PF07690.16 KNZ75019.1 - 8.9e-39 133.4 40.0 6.4e-38 130.6 30.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ75019.1 - 3.3e-07 29.5 12.4 3.3e-07 29.5 12.4 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KNZ75019.1 - 0.0057 15.0 0.5 0.0057 15.0 0.5 2.3 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 KNZ75019.1 - 0.23 9.8 12.9 0.0064 14.9 5.9 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Oxidored_FMN PF00724.20 KNZ75020.1 - 3.2e-55 187.8 0.0 4.2e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fructosamin_kin PF03881.14 KNZ75021.1 - 2e-55 188.1 0.0 2.6e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KNZ75021.1 - 8e-07 29.2 0.0 2.2e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.28 KNZ75022.1 - 6.7e-118 394.1 0.1 1e-117 393.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KNZ75022.1 - 6.5e-69 231.5 0.0 9.4e-69 231.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KNZ75022.1 - 7.3e-49 166.0 0.2 1.9e-48 164.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KNZ75022.1 - 5.8e-32 110.0 0.5 1.3e-31 108.8 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 KNZ75022.1 - 2.3e-26 91.8 0.2 6.2e-26 90.5 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KNZ75022.1 - 1.6e-25 89.0 0.2 4.2e-25 87.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KNZ75022.1 - 3.8e-22 78.6 0.1 1.1e-21 77.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 KNZ75022.1 - 1.8 9.3 4.4 0.59 10.9 0.7 2.0 2 0 0 2 2 2 0 MRN-interacting protein Lung_7-TM_R PF06814.13 KNZ75023.1 - 2.3e-50 171.5 13.2 3.2e-50 171.1 13.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3099 PF11298.8 KNZ75023.1 - 0.027 14.6 0.9 0.027 14.6 0.9 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3099) AgrB PF04647.15 KNZ75023.1 - 0.19 11.0 8.9 0.29 10.4 7.9 1.8 1 1 0 1 1 1 0 Accessory gene regulator B PX PF00787.24 KNZ75024.1 - 2.9e-21 75.5 0.1 1.2e-20 73.6 0.2 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KNZ75024.1 - 9.3e-05 22.1 6.0 0.0012 18.5 2.8 2.7 1 1 2 3 3 3 2 Vps5 C terminal like BAR_3 PF16746.5 KNZ75024.1 - 0.038 13.7 0.3 0.23 11.1 0.1 2.1 2 0 0 2 2 2 0 BAR domain of APPL family RmlD_sub_bind PF04321.17 KNZ75025.1 - 0.0002 20.6 0.0 0.00026 20.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KNZ75025.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KNZ75025.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Myb_DNA-bind_7 PF15963.5 KNZ75026.1 - 1.8e-18 66.2 2.2 1.1e-14 54.0 0.0 2.9 3 0 0 3 3 3 2 Myb DNA-binding like Myb_DNA-binding PF00249.31 KNZ75026.1 - 4e-07 30.1 0.0 0.0001 22.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ75026.1 - 0.00081 19.6 0.3 0.0069 16.6 0.0 2.5 2 1 0 2 2 2 1 Myb-like DNA-binding domain Ribonuclease_T2 PF00445.18 KNZ75029.1 - 1.7e-36 126.2 0.1 2.3e-36 125.7 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family GP3 PF03076.14 KNZ75029.1 - 0.069 13.2 1.0 0.1 12.7 0.2 1.7 2 0 0 2 2 2 0 Equine arteritis virus GP3 Rad51 PF08423.11 KNZ75030.1 - 5e-87 291.4 0.0 2e-86 289.4 0.0 1.8 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 KNZ75030.1 - 6.2e-07 29.1 0.8 1.4e-05 24.7 0.8 2.1 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KNZ75030.1 - 3.9e-05 23.1 0.9 0.00017 21.0 0.9 1.9 1 1 0 1 1 1 1 KaiC CWC25 PF12542.8 KNZ75031.1 - 2.9e-24 85.9 0.3 2.9e-24 85.9 0.3 3.5 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KNZ75031.1 - 8.3e-14 51.5 12.6 8.3e-14 51.5 12.6 4.4 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR Ion_trans PF00520.31 KNZ75032.1 - 9.6e-05 21.7 4.6 0.00011 21.5 4.6 1.1 1 0 0 1 1 1 1 Ion transport protein I_LWEQ PF01608.17 KNZ75034.1 - 7.1e-56 188.7 11.8 7.1e-56 188.7 11.8 5.7 4 1 1 5 5 5 2 I/LWEQ domain TcdB_N PF12918.7 KNZ75034.1 - 0.027 14.7 4.5 0.033 14.5 0.2 2.9 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain FAA_hydro_N_2 PF18288.1 KNZ75034.1 - 2.1 8.8 8.7 0.35 11.3 0.7 3.8 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 SURF1 PF02104.15 KNZ75035.1 - 5.3e-46 157.1 0.0 6.2e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 SURF1 family SIR2 PF02146.17 KNZ75037.1 - 3.7e-33 114.9 0.0 1.3e-21 77.4 0.0 2.3 2 0 0 2 2 2 2 Sir2 family Tnp_22_trimer PF17489.2 KNZ75037.1 - 0.14 12.1 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain RNA_pol_Rpb6 PF01192.22 KNZ75038.1 - 5.3e-15 55.1 0.1 7.7e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 RRM_1 PF00076.22 KNZ75039.1 - 2.5e-15 56.0 0.0 3.9e-07 29.8 0.1 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ75039.1 - 0.0024 17.7 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif ParA PF10609.9 KNZ75040.1 - 4.9e-63 212.9 0.0 7.4e-63 212.3 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase DRIM PF07539.12 KNZ75043.1 - 4.6e-180 600.0 6.4 4.6e-180 600.0 6.4 4.3 3 1 1 4 4 4 2 Down-regulated in metastasis Ribonuc_2-5A PF06479.12 KNZ75043.1 - 0.044 14.0 0.1 0.66 10.1 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease 2-5A DUF1517 PF07466.11 KNZ75043.1 - 0.062 13.4 0.2 0.28 11.3 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) HisKA PF00512.25 KNZ75043.1 - 0.073 13.1 0.1 0.76 9.9 0.1 3.0 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain zf-U1 PF06220.12 KNZ75044.1 - 4e-10 39.3 0.8 6e-10 38.7 0.8 1.3 1 0 0 1 1 1 1 U1 zinc finger DUF1326 PF07040.11 KNZ75044.1 - 0.35 10.9 1.5 1 9.4 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1326) MFS_1 PF07690.16 KNZ75045.1 - 3.3e-13 49.3 34.9 4.5e-13 48.8 33.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KNZ75045.1 - 0.01 14.1 1.1 0.01 14.1 1.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3084 PF11283.8 KNZ75045.1 - 0.99 9.4 5.6 4.4 7.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) UPF0020 PF01170.18 KNZ75046.1 - 3.1e-08 33.6 0.0 1.7e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 KNZ75046.1 - 0.0066 16.2 0.0 2.8 7.6 0.0 2.6 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 KNZ75046.1 - 0.19 11.0 0.0 1.4 8.1 0.0 2.0 1 1 0 1 1 1 0 N-6 DNA Methylase SWIM PF04434.17 KNZ75047.1 - 7.9e-05 22.2 0.2 0.00015 21.4 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-4CXXC_R1 PF10497.9 KNZ75048.1 - 1.8e-09 37.7 11.3 3.5e-09 36.8 11.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 P120R PF08062.11 KNZ75048.1 - 0.11 12.9 1.1 0.5 10.8 1.1 2.2 1 0 0 1 1 1 0 P120R (NUC006) repeat Tim17 PF02466.19 KNZ75049.1 - 7.3e-30 103.6 8.3 9.4e-30 103.2 8.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pyrid_ox_like PF16242.5 KNZ75050.1 - 1.8e-29 102.3 0.0 2.6e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 KNZ75050.1 - 1.8e-12 47.3 0.0 3.1e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Antimicrobial19 PF08225.11 KNZ75050.1 - 0.032 13.8 1.2 0.07 12.7 0.6 1.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Rad9 PF04139.13 KNZ75051.1 - 1e-35 123.4 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Rad9 DUF4168 PF13767.6 KNZ75052.1 - 0.015 16.4 0.9 0.042 15.0 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) Amidase PF01425.21 KNZ75054.1 - 1.2e-101 341.0 0.0 2.4e-101 339.9 0.0 1.5 1 1 0 1 1 1 1 Amidase PigN PF04987.14 KNZ75055.1 - 7.8e-126 420.6 31.5 1e-125 420.2 31.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KNZ75055.1 - 1.5e-10 41.2 0.3 2.8e-07 30.5 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KNZ75055.1 - 1.4e-05 24.6 0.0 3.1e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KNZ75055.1 - 0.02 14.3 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Cys_Met_Meta_PP PF01053.20 KNZ75056.1 - 9.1e-132 439.2 0.0 1.1e-131 438.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KNZ75056.1 - 7.8e-11 41.7 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KNZ75056.1 - 2.6e-09 36.5 0.2 5.1e-09 35.6 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KNZ75056.1 - 6.1e-09 35.6 0.2 1.1e-08 34.8 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 KNZ75056.1 - 0.0027 16.3 0.1 0.0067 15.0 0.0 1.6 2 0 0 2 2 2 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 KNZ75056.1 - 0.028 13.7 0.1 0.36 10.1 0.1 2.2 1 1 0 1 1 1 0 Beta-eliminating lyase Prp18 PF02840.15 KNZ75058.1 - 0.082 13.0 0.1 0.094 12.8 0.1 1.1 1 0 0 1 1 1 0 Prp18 domain Cys_Met_Meta_PP PF01053.20 KNZ75060.1 - 1.4e-54 185.1 0.0 3.5e-38 131.1 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme RNase_H PF00075.24 KNZ75061.1 - 1.1e-05 25.7 0.1 5.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 RNase H Tektin PF03148.14 KNZ75062.1 - 0.079 11.7 0.0 0.09 11.5 0.0 1.1 1 0 0 1 1 1 0 Tektin family RNase_H PF00075.24 KNZ75063.1 - 0.00039 20.6 0.1 0.001 19.3 0.1 1.7 1 0 0 1 1 1 1 RNase H DUF2120 PF09893.9 KNZ75063.1 - 0.22 11.6 1.7 2.2 8.4 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) p450 PF00067.22 KNZ75064.1 - 1.1e-62 212.3 0.0 1.3e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_S19 PF00203.21 KNZ75065.1 - 5.9e-25 87.0 0.0 9e-25 86.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 zf-C3HC4_3 PF13920.6 KNZ75067.1 - 7.8e-06 25.7 7.4 7.8e-06 25.7 7.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 KNZ75067.1 - 0.17 12.4 12.6 2.2 8.9 0.0 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C3HC4_2 PF13923.6 KNZ75067.1 - 1.6 8.7 13.0 0.2 11.6 7.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ75067.1 - 1.8 8.6 13.1 1.6 8.7 8.3 2.5 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KNZ75067.1 - 3.4 7.6 18.0 0.053 13.4 8.3 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L37 PF08561.10 KNZ75068.1 - 3.6e-13 50.1 11.4 9.3e-13 48.8 0.8 3.0 3 0 0 3 3 3 2 Mitochondrial ribosomal protein L37 ADH_N PF08240.12 KNZ75069.1 - 6.3e-28 96.8 2.9 1.5e-27 95.7 2.9 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ75069.1 - 6.5e-22 77.9 0.7 1.3e-21 77.0 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ75069.1 - 1.9e-05 25.7 0.0 3.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KNZ75069.1 - 0.014 14.9 0.3 0.022 14.2 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TTC5_OB PF16669.5 KNZ75069.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain AlaDh_PNT_C PF01262.21 KNZ75069.1 - 0.13 11.6 0.4 0.24 10.6 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Gag_p15 PF08723.10 KNZ75069.1 - 0.14 12.4 0.0 0.68 10.2 0.0 2.0 2 0 0 2 2 2 0 Gag protein p15 SH3_15 PF18346.1 KNZ75069.1 - 0.18 12.1 0.5 7 7.1 0.2 2.7 2 1 0 2 2 2 0 Mind bomb SH3 repeat domain PUL PF08324.11 KNZ75069.1 - 0.33 10.2 0.6 7.3 5.7 0.3 2.1 2 0 0 2 2 2 0 PUL domain ADH_N PF08240.12 KNZ75070.1 - 8.7e-28 96.4 2.8 1.8e-27 95.3 2.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ75070.1 - 2.4e-24 85.7 0.5 5.4e-24 84.6 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ75070.1 - 0.00057 21.0 0.1 0.0011 20.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TTC5_OB PF16669.5 KNZ75070.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain Choline_transpo PF04515.12 KNZ75071.1 - 5.5e-50 170.4 8.6 5.5e-50 170.4 8.6 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4164 PF13747.6 KNZ75072.1 - 0.02 15.2 0.5 0.065 13.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FAM177 PF14774.6 KNZ75072.1 - 0.21 12.0 1.3 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 FAM177 family DIM1 PF02966.16 KNZ75074.1 - 4.5e-39 133.3 0.0 3.8e-29 101.1 0.0 2.0 1 1 1 2 2 2 2 Mitosis protein DIM1 Thioredoxin PF00085.20 KNZ75074.1 - 0.00033 20.6 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KNZ75074.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like ORC6 PF05460.13 KNZ75075.1 - 1.7 7.8 6.5 2.4 7.4 6.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Retrotrans_gag PF03732.17 KNZ75082.1 - 0.00057 20.1 0.1 0.0019 18.4 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4939 PF16297.5 KNZ75082.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) PEP-CTERM PF07589.11 KNZ75085.1 - 0.045 13.8 0.2 0.045 13.8 0.2 2.5 3 0 0 3 3 3 0 PEP-CTERM motif Pyr_redox_2 PF07992.14 KNZ75086.1 - 2.8e-05 23.5 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Cation_efflux PF01545.21 KNZ75087.1 - 3.2e-51 173.9 14.4 4e-51 173.6 14.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2157 PF09925.9 KNZ75087.1 - 0.00072 19.4 0.7 0.13 12.0 0.0 2.8 1 1 1 2 2 2 1 Predicted membrane protein (DUF2157) MASE4 PF17158.4 KNZ75087.1 - 0.012 14.9 3.0 0.012 14.9 3.0 1.7 1 1 0 1 1 1 0 Membrane-associated sensor, integral membrane domain WD40 PF00400.32 KNZ75089.1 - 1.6e-14 54.1 8.5 0.0058 17.4 0.2 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75089.1 - 1.1e-10 41.6 0.0 0.22 11.9 0.0 5.4 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KNZ75089.1 - 0.015 14.4 0.0 2.9 6.8 0.0 2.4 1 1 1 2 2 2 0 Coatomer WD associated region DUF1192 PF06698.11 KNZ75089.1 - 0.071 13.2 0.1 0.071 13.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Mcl1_mid PF12341.8 KNZ75089.1 - 0.15 11.3 0.0 5.2 6.3 0.0 2.4 3 0 0 3 3 3 0 Minichromosome loss protein, Mcl1, middle region Shugoshin_N PF07558.11 KNZ75089.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Utp8 PF10395.9 KNZ75089.1 - 0.18 10.3 0.0 0.41 9.1 0.0 1.7 1 0 0 1 1 1 0 Utp8 family DnaJ PF00226.31 KNZ75090.1 - 7.2e-20 70.9 0.2 1.1e-19 70.3 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF5559 PF17714.1 KNZ75090.1 - 0.075 12.9 1.7 1.8 8.4 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5559) HTH_10 PF04967.12 KNZ75090.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain SH3_1 PF00018.28 KNZ75092.1 - 3.5e-18 64.9 1.8 5e-08 32.4 0.2 2.8 2 0 0 2 2 2 2 SH3 domain SAM_1 PF00536.30 KNZ75092.1 - 8.2e-13 48.6 0.0 1.3e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 KNZ75092.1 - 8.2e-13 48.0 2.1 2.4e-05 24.1 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.17 KNZ75092.1 - 1.6e-11 44.2 0.0 2.8e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KNZ75092.1 - 4.3e-07 29.5 0.3 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 KNZ75092.1 - 3.1e-06 27.7 0.0 6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 KNZ75092.1 - 0.004 17.4 3.5 0.15 12.3 0.4 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain SlyX PF04102.12 KNZ75092.1 - 0.032 14.9 0.4 0.098 13.3 0.4 1.8 1 0 0 1 1 1 0 SlyX ADIP PF11559.8 KNZ75092.1 - 0.14 12.3 0.5 0.29 11.2 0.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BRAP2 PF07576.12 KNZ75093.1 - 1.2e-28 99.2 0.0 1.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 KNZ75093.1 - 1.1e-19 70.5 5.1 2e-19 69.7 5.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein RRM_1 PF00076.22 KNZ75093.1 - 0.00057 19.7 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UBP_var PF17807.1 KNZ75093.1 - 0.068 12.9 0.8 0.13 12.0 0.8 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger WXG100 PF06013.12 KNZ75093.1 - 0.29 11.4 3.9 0.45 10.8 2.8 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Nup88 PF10168.9 KNZ75093.1 - 1.8 6.3 8.7 2.5 5.8 8.7 1.1 1 0 0 1 1 1 0 Nuclear pore component IFT20 PF14931.6 KNZ75093.1 - 2.9 8.1 13.8 0.36 11.0 5.7 2.4 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF4407 PF14362.6 KNZ75093.1 - 3.7 6.8 13.0 5.9 6.2 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 KNZ75093.1 - 8.4 5.5 9.4 13 4.9 9.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 NUDIX PF00293.28 KNZ75094.1 - 1.5e-10 41.2 0.0 2.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Vma12 PF11712.8 KNZ75095.1 - 1.1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Tmemb_14 PF03647.13 KNZ75095.1 - 0.097 13.4 0.2 0.17 12.7 0.2 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C SCIMP PF15050.6 KNZ75095.1 - 0.13 12.7 0.2 0.24 11.8 0.1 1.5 2 0 0 2 2 2 0 SCIMP protein Atx10homo_assoc PF09759.9 KNZ75096.1 - 1.4e-23 82.8 0.1 1e-22 80.0 0.0 2.4 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 KNZ75096.1 - 0.29 11.2 1.0 44 4.3 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Leo1 PF04004.13 KNZ75097.1 - 3.7e-52 176.5 0.1 3.7e-52 176.5 0.1 1.8 2 0 0 2 2 2 1 Leo1-like protein SQHop_cyclase_N PF13249.6 KNZ75100.1 - 1.6e-46 158.7 0.0 7.6e-41 140.1 0.0 3.0 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 KNZ75100.1 - 3.7e-40 138.0 1.4 4.6e-37 127.8 0.1 3.0 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 KNZ75100.1 - 7.5e-29 99.2 8.4 1.4e-10 40.7 0.4 5.0 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KNZ75100.1 - 0.0042 16.5 0.2 2.7 7.3 0.0 3.7 4 1 1 5 5 5 2 Pectic acid lyase Actin PF00022.19 KNZ75101.1 - 2.6e-34 118.6 0.0 3.3e-33 114.9 0.0 2.0 1 1 0 1 1 1 1 Actin Ribosomal_L7Ae PF01248.26 KNZ75102.1 - 1.8e-22 78.9 0.0 2.1e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DNA_pol_B PF00136.21 KNZ75103.1 - 2e-133 445.5 0.8 1.2e-107 360.5 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KNZ75103.1 - 2.9e-85 286.4 0.0 6.9e-85 285.2 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KNZ75103.1 - 5.1e-18 65.3 8.1 1.1e-17 64.3 8.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KNZ75103.1 - 0.0011 17.9 2.3 0.0036 16.2 0.1 2.3 2 1 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 KNZ75103.1 - 0.053 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 KNZ75103.1 - 0.17 11.8 4.4 0.61 10.0 4.4 1.9 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PMM PF03332.13 KNZ75104.1 - 2.8e-107 357.5 0.4 3.2e-107 357.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 KNZ75104.1 - 8.1e-05 22.5 0.0 0.0025 17.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KNZ75104.1 - 0.04 14.3 0.2 2.3 8.6 0.0 2.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ75104.1 - 0.048 14.0 0.1 0.075 13.3 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase bVLRF1 PF18826.1 KNZ75105.1 - 2.1e-53 180.2 0.2 4.6e-53 179.1 0.2 1.6 1 1 0 1 1 1 1 bacteroidetes VLRF1 release factor TRAUB PF08164.12 KNZ75106.1 - 9.7e-29 99.7 0.7 1.9e-28 98.8 0.0 1.9 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KNZ75106.1 - 2.8e-25 89.6 2.4 3.2e-24 86.2 0.0 2.7 2 1 1 3 3 3 1 Apoptosis antagonizing transcription factor RR_TM4-6 PF06459.12 KNZ75106.1 - 6.7 6.5 7.8 0.89 9.3 2.6 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PX PF00787.24 KNZ75107.1 - 2.4e-24 85.5 0.3 1.7e-23 82.7 0.1 2.3 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KNZ75107.1 - 6.3e-07 29.2 10.3 0.00027 20.6 2.0 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 KNZ75107.1 - 0.27 10.9 8.8 0.041 13.5 1.7 2.1 2 0 0 2 2 2 0 BAR domain DUF4391 PF14335.6 KNZ75107.1 - 1.2 8.8 6.8 0.17 11.5 1.4 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4391) Exonuc_VII_L PF02601.15 KNZ75107.1 - 1.3 8.6 5.3 1.6 8.2 0.7 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3450 PF11932.8 KNZ75107.1 - 6 6.1 8.8 0.59 9.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) AAA_33 PF13671.6 KNZ75108.1 - 1.2e-11 44.9 0.0 0.00017 21.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 KNZ75108.1 - 0.00036 21.1 0.0 0.0011 19.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KNZ75108.1 - 0.0012 18.4 0.0 0.16 11.4 0.0 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 G-alpha PF00503.20 KNZ75108.1 - 0.0017 17.6 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.6 KNZ75108.1 - 0.0059 16.9 0.0 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain tRNA_lig_kinase PF08303.11 KNZ75108.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain NB-ARC PF00931.22 KNZ75108.1 - 0.028 13.6 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain TIR_2 PF13676.6 KNZ75108.1 - 0.036 14.7 0.0 0.058 14.0 0.0 1.3 1 0 0 1 1 1 0 TIR domain ATP_bind_1 PF03029.17 KNZ75108.1 - 0.044 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 KNZ75108.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase dNK PF01712.19 KNZ75108.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase TPR_11 PF13414.6 KNZ75109.1 - 3.4e-15 55.5 6.4 3.2e-08 33.1 0.8 4.3 2 2 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 KNZ75109.1 - 7.6e-15 53.8 7.3 8e-08 31.8 0.0 5.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ75109.1 - 9.2e-15 53.7 1.2 2.4e-08 33.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ75109.1 - 4e-12 45.6 0.1 0.034 14.5 0.0 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ75109.1 - 9.4e-12 45.4 6.7 1.2e-05 25.9 0.1 3.8 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ75109.1 - 6e-11 42.5 10.0 3.9e-05 23.9 0.5 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ75109.1 - 2e-10 41.0 1.5 0.00047 20.6 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75109.1 - 1.5e-07 31.6 8.5 0.0014 19.3 0.0 4.6 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ75109.1 - 2.4e-07 30.4 6.0 0.0013 18.8 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ75109.1 - 1.4e-06 27.9 5.7 0.0045 16.8 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ75109.1 - 2.4e-05 24.7 0.4 0.024 15.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ75109.1 - 5.8e-05 22.8 7.5 0.027 14.5 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ75109.1 - 0.0001 22.5 0.8 0.0039 17.4 0.6 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KNZ75109.1 - 0.00011 21.6 0.4 0.00014 21.2 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC5 PF12862.7 KNZ75109.1 - 0.00039 20.4 0.1 0.00072 19.6 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 KNZ75109.1 - 0.003 17.8 1.0 0.23 11.8 0.0 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KNZ75109.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 KNZ75109.1 - 0.026 14.6 1.4 6.9 6.8 0.0 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 KNZ75109.1 - 0.053 14.2 5.7 0.92 10.3 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ75109.1 - 0.072 13.3 0.4 9.5 6.4 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat Tim17 PF02466.19 KNZ75110.1 - 3.3e-24 85.4 8.7 4.3e-24 85.0 8.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Velvet PF11754.8 KNZ75111.1 - 1.8e-28 100.1 2.2 2.8e-16 60.2 0.1 2.6 2 1 1 3 3 3 2 Velvet factor Cytochrom_C1 PF02167.15 KNZ75112.1 - 3.1e-98 327.9 0.0 3.7e-98 327.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KNZ75112.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 KNZ75112.1 - 0.01 16.9 0.2 0.038 15.1 0.2 2.0 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.16 KNZ75113.1 - 5.3e-20 72.0 5.5 2.7e-18 66.4 5.4 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 KNZ75113.1 - 9.3e-07 28.9 0.2 2.5e-06 27.5 0.2 1.7 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family tRNA_int_endo PF01974.17 KNZ75114.1 - 1.5e-15 57.0 0.2 5e-15 55.3 0.2 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KNZ75114.1 - 0.007 16.0 0.1 0.034 13.8 0.0 2.0 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain DUF1951 PF09188.10 KNZ75114.1 - 0.22 11.5 0.5 8.4 6.4 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1951) WD40 PF00400.32 KNZ75115.1 - 1.3e-10 41.7 12.6 0.11 13.4 0.2 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Dynein_IC2 PF11540.8 KNZ75115.1 - 0.029 14.3 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 HAND PF09110.11 KNZ75115.1 - 1.4 9.7 9.1 2.9 8.7 9.1 1.4 1 0 0 1 1 1 0 HAND F-box-like PF12937.7 KNZ75116.1 - 0.00019 21.3 0.3 0.00078 19.3 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ75116.1 - 0.087 12.7 0.6 0.64 10.0 0.0 2.9 2 0 0 2 2 2 0 F-box domain Ribosomal_S27 PF01599.19 KNZ75117.1 - 1.1e-26 92.7 2.0 1.1e-26 92.7 2.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 KNZ75117.1 - 1.4e-18 66.3 0.8 8.2e-18 63.9 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 KNZ75117.1 - 4.9e-08 32.7 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 KNZ75117.1 - 0.0038 17.3 0.1 0.0075 16.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 KNZ75117.1 - 0.035 14.3 0.3 0.067 13.4 0.3 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF971 PF06155.12 KNZ75117.1 - 0.15 12.7 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Rep_fac_C PF08542.11 KNZ75118.1 - 2.8e-23 82.1 0.0 1.3e-22 80.0 0.1 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 KNZ75118.1 - 4.2e-18 66.1 0.0 7.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KNZ75118.1 - 3.1e-15 56.3 0.0 3.7e-11 43.1 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KNZ75118.1 - 6.2e-08 32.8 0.0 2.4e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KNZ75118.1 - 2.6e-07 30.5 0.1 1.2e-06 28.4 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 KNZ75118.1 - 1.3e-06 28.4 0.1 3.6e-06 27.0 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 KNZ75118.1 - 7.9e-06 25.2 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 KNZ75118.1 - 1.3e-05 25.1 0.6 0.00043 20.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 KNZ75118.1 - 1.9e-05 24.9 0.1 7e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain AAA_16 PF13191.6 KNZ75118.1 - 2.3e-05 24.8 0.0 4.9e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KNZ75118.1 - 3.3e-05 23.7 0.0 0.00024 20.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 KNZ75118.1 - 0.0001 22.1 0.2 0.00027 20.8 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 KNZ75118.1 - 0.00014 22.2 0.7 0.59 10.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 KNZ75118.1 - 0.00014 22.2 2.1 0.032 14.6 0.0 2.9 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 KNZ75118.1 - 0.00017 21.6 0.3 0.0049 16.9 0.1 3.1 2 2 1 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KNZ75118.1 - 0.00017 21.4 0.0 0.00047 19.9 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain ResIII PF04851.15 KNZ75118.1 - 0.00073 19.6 0.0 0.032 14.2 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNZ75118.1 - 0.0015 18.4 0.3 0.0071 16.1 0.4 1.9 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_3 PF07726.11 KNZ75118.1 - 0.0015 18.4 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 KNZ75118.1 - 0.003 17.1 0.0 0.0059 16.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 KNZ75118.1 - 0.0048 16.3 0.1 0.16 11.4 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KNZ75118.1 - 0.009 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Methyltransf_31 PF13847.6 KNZ75118.1 - 0.012 15.4 0.1 0.034 13.9 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Viral_helicase1 PF01443.18 KNZ75118.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 KNZ75118.1 - 0.016 15.4 0.2 0.042 14.1 0.1 1.8 2 1 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 KNZ75118.1 - 0.016 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KNZ75118.1 - 0.022 13.8 0.0 0.049 12.7 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein MCM PF00493.23 KNZ75118.1 - 0.034 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 KNZ75118.1 - 0.046 14.2 0.0 0.87 10.1 0.0 2.5 2 1 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 KNZ75118.1 - 0.061 12.7 0.0 0.31 10.4 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 KNZ75118.1 - 0.067 12.4 0.0 0.62 9.2 0.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 KNZ75118.1 - 0.081 11.6 0.0 0.14 10.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DALR_1 PF05746.15 KNZ75118.1 - 0.12 12.5 1.9 0.75 10.0 0.1 2.8 2 2 1 3 3 3 0 DALR anticodon binding domain AAA_25 PF13481.6 KNZ75118.1 - 0.14 11.7 0.1 0.84 9.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain TPR_6 PF13174.6 KNZ75118.1 - 0.35 11.6 1.7 7.8 7.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Zw10 PF06248.13 KNZ75119.1 - 8.1e-19 67.6 0.2 1.7e-18 66.5 0.1 1.5 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 KNZ75119.1 - 2.4e-10 40.5 0.0 5.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal MutL_C PF08676.11 KNZ75119.1 - 0.039 13.7 0.4 2.7 7.7 0.0 2.9 2 1 0 2 2 2 0 MutL C terminal dimerisation domain Tweety PF04906.13 KNZ75119.1 - 0.053 12.2 0.6 0.15 10.7 0.4 1.8 2 0 0 2 2 2 0 Tweety DUF1664 PF07889.12 KNZ75119.1 - 0.13 12.3 0.6 0.41 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 KNZ75119.1 - 0.14 12.6 1.3 1.8 9.1 0.4 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 KNZ75119.1 - 0.16 12.0 8.1 0.39 10.8 4.2 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 KNZ75119.1 - 0.16 12.7 0.2 27 5.6 0.0 2.8 2 0 0 2 2 2 0 Occludin homology domain Vps54_N PF10475.9 KNZ75119.1 - 0.3 10.3 3.8 15 4.8 2.5 2.5 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex DUF4164 PF13747.6 KNZ75119.1 - 1.2 9.5 5.1 15 5.9 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RED_N PF07808.13 KNZ75120.1 - 4.1e-14 52.7 12.0 4.1e-14 52.7 12.0 2.2 2 0 0 2 2 2 1 RED-like protein N-terminal region DUF4148 PF13663.6 KNZ75120.1 - 4.1 7.7 5.6 9.4 6.5 0.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4148) NIR_SIR PF01077.22 KNZ75121.1 - 2.8e-49 166.7 0.0 1.2e-43 148.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 KNZ75121.1 - 1.2e-34 118.0 0.0 6.6e-16 57.9 0.0 2.7 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 KNZ75121.1 - 1.6e-25 90.0 0.1 2.7e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin PIG-L PF02585.17 KNZ75122.1 - 5.8e-23 82.0 0.0 8.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase UvrD_C_2 PF13538.6 KNZ75122.1 - 0.06 13.2 0.7 1.8 8.4 0.3 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain ALS2CR11 PF15729.5 KNZ75123.1 - 0.088 11.9 2.8 0.13 11.3 2.8 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 Aminotran_5 PF00266.19 KNZ75124.1 - 1.4e-21 76.9 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KNZ75124.1 - 0.035 14.1 0.1 0.084 12.9 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain KR PF08659.10 KNZ75124.1 - 0.036 14.0 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain Aminotran_5 PF00266.19 KNZ75125.1 - 2.3e-23 82.8 0.0 3.1e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KNZ75125.1 - 0.0069 15.6 0.0 0.023 13.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II PET117 PF15786.5 KNZ75126.1 - 2e-25 88.8 3.0 2.3e-25 88.6 3.0 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4500 PF14937.6 KNZ75126.1 - 0.012 15.6 0.3 0.023 14.7 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4500) MAS20 PF02064.15 KNZ75126.1 - 0.038 14.1 2.6 0.042 13.9 2.6 1.0 1 0 0 1 1 1 0 MAS20 protein import receptor CTD_bind PF04818.13 KNZ75127.1 - 6.8e-05 23.6 0.0 0.00014 22.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. PAP2 PF01569.21 KNZ75128.1 - 8.8e-11 41.7 2.3 1.1e-10 41.4 2.3 1.2 1 0 0 1 1 1 1 PAP2 superfamily SNF2_N PF00176.23 KNZ75129.1 - 9.7e-15 54.1 0.1 3e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KNZ75129.1 - 1.7e-14 53.9 3.9 1.2e-13 51.1 0.0 2.9 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KNZ75129.1 - 7.5e-07 29.5 0.1 1.9e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ75129.1 - 0.00037 20.6 0.4 0.11 12.5 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 KNZ75129.1 - 0.0035 17.3 2.5 0.0035 17.3 2.5 2.6 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KNZ75129.1 - 0.097 12.5 4.7 0.34 10.8 4.7 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 A2L_zn_ribbon PF08792.10 KNZ75129.1 - 1.4 8.8 4.3 0.67 9.7 1.2 2.2 1 1 0 1 1 1 0 A2L zinc ribbon domain IBR PF01485.21 KNZ75129.1 - 3.3 8.0 11.7 9.9 6.5 1.9 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS91 PF14319.6 KNZ75129.1 - 8.3 6.5 6.9 34 4.6 1.0 2.9 2 0 0 2 2 2 0 Transposase zinc-binding domain FYVE PF01363.21 KNZ75129.1 - 9.6 6.4 8.2 23 5.2 1.3 2.8 2 0 0 2 2 2 0 FYVE zinc finger Cript PF10235.9 KNZ75130.1 - 3e-28 98.2 5.9 3.3e-28 98.1 5.9 1.0 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 KNZ75130.1 - 0.0032 17.8 6.0 0.0034 17.7 6.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) PolC_DP2 PF03833.13 KNZ75130.1 - 0.14 10.0 1.9 0.14 10.0 1.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 NOB1_Zn_bind PF08772.11 KNZ75130.1 - 0.2 11.8 7.4 9.6 6.5 7.4 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 KNZ75130.1 - 0.41 10.4 9.5 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf_UBZ PF18439.1 KNZ75130.1 - 1.1 8.9 4.4 2 8.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-dskA_traR PF01258.17 KNZ75130.1 - 1.6 8.7 6.6 5.2 7.1 0.1 3.3 2 1 2 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger Methyltransf_16 PF10294.9 KNZ75132.1 - 5.4e-16 58.8 0.0 7.2e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 KNZ75132.1 - 0.012 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.6 KNZ75132.1 - 0.066 13.9 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 KNZ75132.1 - 0.095 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) WD40 PF00400.32 KNZ75133.1 - 1.5e-20 73.1 15.8 0.0058 17.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KNZ75133.1 - 0.0049 15.9 0.1 0.29 10.0 0.0 2.6 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DZR PF12773.7 KNZ75133.1 - 0.04 13.9 7.3 54 3.9 7.3 3.4 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KNZ75133.1 - 0.052 13.0 7.5 15 5.1 0.1 4.0 3 0 0 3 3 3 0 zinc-ribbon domain DUF2688 PF10892.8 KNZ75133.1 - 0.59 9.6 4.0 0.58 9.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) zinc_ribbon_2 PF13240.6 KNZ75133.1 - 1.3 8.8 7.9 9.1 6.2 0.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain SIR2 PF02146.17 KNZ75134.1 - 2e-19 70.2 0.0 4.9e-19 68.9 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Zn_clus PF00172.18 KNZ75135.1 - 3e-12 46.4 42.7 7.6e-05 22.8 2.9 4.2 3 1 1 4 4 4 4 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_B PF02304.15 KNZ75135.1 - 0.14 12.5 0.2 0.14 12.5 0.2 1.6 2 0 0 2 2 2 0 Scaffold protein B Glyco_hydro_16 PF00722.21 KNZ75136.1 - 3.5e-05 23.4 0.0 6.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 KNZ75137.1 - 0.00011 21.7 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BCS1_N PF08740.11 KNZ75138.1 - 1.4e-45 155.5 1.2 3e-45 154.5 0.9 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KNZ75138.1 - 1.1e-17 64.7 0.0 3e-17 63.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ75138.1 - 0.00076 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 KNZ75138.1 - 0.0034 16.6 0.0 0.0061 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KNZ75138.1 - 0.041 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNZ75138.1 - 0.051 13.6 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KNZ75138.1 - 0.087 13.4 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KNZ75138.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KNZ75138.1 - 0.11 12.6 0.0 0.3 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain Carb_kinase PF01256.17 KNZ75139.1 - 9e-51 172.7 0.0 1.2e-50 172.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KNZ75139.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase PGM_PMM_I PF02878.16 KNZ75140.1 - 1.6e-36 125.0 0.2 2.6e-36 124.4 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 KNZ75140.1 - 3.5e-26 91.6 0.0 6.8e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KNZ75140.1 - 5.6e-15 55.8 0.0 1.8e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KNZ75140.1 - 1e-05 25.6 0.0 2.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Glyco_hydro_57 PF03065.15 KNZ75140.1 - 0.039 13.1 0.0 0.076 12.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 PAP2 PF01569.21 KNZ75141.1 - 4.6e-07 29.7 9.9 1.5e-06 28.0 8.9 2.3 1 1 0 1 1 1 1 PAP2 superfamily Tudor-knot PF11717.8 KNZ75143.1 - 0.0054 16.6 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KNZ75143.1 - 0.032 14.1 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Pantoate_ligase PF02569.15 KNZ75144.1 - 2.8e-89 298.9 0.0 3.2e-89 298.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase MBOAT_2 PF13813.6 KNZ75145.1 - 1.1e-16 60.8 3.4 3.3e-16 59.3 3.4 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_25 PF13649.6 KNZ75146.1 - 4.3e-05 24.1 0.0 0.0013 19.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ75146.1 - 0.13 13.0 0.0 0.61 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ75147.1 - 3.7e-05 24.3 0.0 0.01 16.6 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain HMG_CoA_synt_C PF08540.10 KNZ75148.1 - 2.4e-86 289.8 0.2 3e-86 289.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KNZ75148.1 - 2.2e-82 275.1 0.1 3.2e-82 274.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3641 PF12345.8 KNZ75148.1 - 0.0027 17.7 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) ACP_syn_III PF08545.10 KNZ75148.1 - 0.0083 16.0 0.1 0.048 13.5 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KNZ75148.1 - 0.0097 16.1 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HMG_CoA_synt_C PF08540.10 KNZ75149.1 - 4.2e-86 289.1 0.1 5.2e-86 288.7 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KNZ75149.1 - 5.5e-82 273.8 0.1 7.9e-82 273.3 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3641 PF12345.8 KNZ75149.1 - 0.0029 17.6 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) ACP_syn_III PF08545.10 KNZ75149.1 - 0.0049 16.7 0.2 0.025 14.4 0.1 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KNZ75149.1 - 0.016 15.3 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribonuc_P_40 PF08584.11 KNZ75150.1 - 5.2e-33 114.6 0.0 7.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit IATP PF04568.12 KNZ75151.1 - 0.14 12.6 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP VPS9 PF02204.18 KNZ75152.1 - 2.1e-31 108.2 0.1 3.4e-31 107.5 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KNZ75152.1 - 6.6e-17 61.6 1.1 2.4e-16 59.8 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 KNZ75152.1 - 1.5e-08 34.2 0.1 4.1e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 KNZ75152.1 - 9.7e-06 25.1 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif MFS_1 PF07690.16 KNZ75154.1 - 2.2e-24 86.0 36.1 3.6e-24 85.4 36.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1752 PF08550.10 KNZ75155.1 - 1.6e-08 34.2 4.3 3.1e-08 33.3 4.3 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FMO-like PF00743.19 KNZ75156.1 - 1.5e-14 53.4 0.0 5.1e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KNZ75156.1 - 3e-13 49.8 0.0 6.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ75156.1 - 2.5e-06 27.3 0.0 0.00012 21.8 0.0 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ75156.1 - 0.00024 21.1 0.1 0.016 15.2 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KNZ75156.1 - 0.00076 18.8 0.0 0.044 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ75156.1 - 0.018 14.2 0.0 2.7 7.1 0.0 2.5 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Vint PF14623.6 KNZ75156.1 - 0.041 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Hint-domain Pyr_redox_3 PF13738.6 KNZ75156.1 - 0.097 11.9 0.0 17 4.6 0.0 2.9 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ75156.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 KNZ75156.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 KNZ75157.1 - 7.7e-22 77.7 24.1 9.6e-21 74.1 26.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PACT_coil_coil PF10495.9 KNZ75158.1 - 9e-14 51.8 5.2 2.1e-13 50.7 0.1 4.2 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein HMMR_N PF15905.5 KNZ75158.1 - 0.00068 19.2 13.7 0.00068 19.2 13.7 8.0 2 2 6 8 8 8 1 Hyaluronan mediated motility receptor N-terminal MscS_porin PF12795.7 KNZ75158.1 - 0.0034 17.0 19.8 0.0034 17.0 19.8 8.4 3 2 6 9 9 9 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 KNZ75158.1 - 0.0065 16.5 18.7 0.0065 16.5 18.7 11.8 4 3 6 10 10 10 4 TPR/MLP1/MLP2-like protein BTB PF00651.31 KNZ75160.1 - 0.0091 16.2 0.1 0.046 14.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 KNZ75161.1 - 6.6e-09 36.0 0.0 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ribosomal_L5_C PF00673.21 KNZ75162.1 - 6.9e-21 74.2 0.0 1.1e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KNZ75162.1 - 7.1e-20 71.1 0.1 1.8e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 NMO PF03060.15 KNZ75163.1 - 2.2e-49 168.6 0.7 2.9e-49 168.2 0.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KNZ75163.1 - 2.7e-06 26.6 0.0 1.7e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KNZ75163.1 - 0.0011 18.1 2.2 0.0017 17.5 2.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1515 PF07439.11 KNZ75164.1 - 0.25 11.4 17.5 0.51 10.4 3.5 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) Prominin PF05478.11 KNZ75164.1 - 0.25 9.3 13.0 0.29 9.0 3.6 2.2 1 1 1 2 2 2 0 Prominin YojJ PF10372.9 KNZ75164.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.8 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Lebercilin PF15619.6 KNZ75164.1 - 0.67 9.6 33.7 3 7.5 32.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 KNZ75164.1 - 3 8.2 34.6 0.35 11.3 16.1 2.8 2 1 1 3 3 3 0 Fez1 NPV_P10 PF05531.12 KNZ75164.1 - 5.5 7.5 11.5 16 6.0 4.5 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 KNZ75164.1 - 7.6 4.9 12.1 10 4.5 12.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 KNZ75165.1 - 3.3e-07 29.7 4.2 4.9e-07 29.1 4.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 KNZ75165.1 - 0.0049 17.1 2.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 KNZ75165.1 - 0.0083 16.3 8.4 0.012 15.8 8.4 1.2 1 0 0 1 1 1 1 Tropomyosin like KIAA1430 PF13879.6 KNZ75165.1 - 0.023 15.5 1.3 0.023 15.5 1.3 2.0 2 0 0 2 2 2 0 KIAA1430 homologue DUF4407 PF14362.6 KNZ75165.1 - 0.028 13.8 6.4 0.037 13.4 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TipAS PF07739.13 KNZ75165.1 - 0.038 14.5 4.1 3.1 8.4 0.0 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain HALZ PF02183.18 KNZ75165.1 - 0.062 13.5 6.6 0.4 10.9 0.3 2.8 3 0 0 3 3 2 0 Homeobox associated leucine zipper zf-C3HC4_2 PF13923.6 KNZ75165.1 - 0.069 13.0 0.9 0.15 12.0 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mod_r PF07200.13 KNZ75165.1 - 0.071 13.2 9.1 0.041 14.0 2.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein zf-C3HC4_4 PF15227.6 KNZ75165.1 - 0.074 13.2 2.6 0.15 12.2 2.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 KNZ75165.1 - 0.077 12.8 3.2 0.2 11.4 3.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger TPR_MLP1_2 PF07926.12 KNZ75165.1 - 0.08 13.0 1.1 0.08 13.0 1.1 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Scaffolding_pro PF11418.8 KNZ75165.1 - 0.18 12.4 2.0 0.73 10.4 0.6 2.5 1 1 2 3 3 3 0 Phi29 scaffolding protein ATG16 PF08614.11 KNZ75165.1 - 0.2 11.9 13.7 1.5 9.0 9.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 KNZ75165.1 - 0.25 10.7 13.9 6.5 6.1 7.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C3HC4_3 PF13920.6 KNZ75165.1 - 0.26 11.2 2.6 0.34 10.8 1.6 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LapA_dom PF06305.11 KNZ75165.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Fib_alpha PF08702.10 KNZ75165.1 - 0.35 11.0 7.7 0.12 12.6 1.2 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family zf-RING_2 PF13639.6 KNZ75165.1 - 0.36 11.2 2.7 0.45 10.9 1.4 1.9 2 0 0 2 2 1 0 Ring finger domain Lebercilin PF15619.6 KNZ75165.1 - 0.38 10.4 13.4 15 5.1 13.4 2.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease zf-RING_UBOX PF13445.6 KNZ75165.1 - 0.41 10.7 3.3 0.89 9.6 3.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Spc7 PF08317.11 KNZ75165.1 - 0.47 9.3 10.0 0.72 8.7 10.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KNZ75165.1 - 0.48 10.5 8.3 5.2 7.1 6.9 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 KNZ75165.1 - 1.1 10.1 8.2 11 6.8 2.2 2.5 2 1 0 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.10 KNZ75165.1 - 1.4 9.1 4.5 22 5.2 2.3 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad3 Fmp27_WPPW PF10359.9 KNZ75165.1 - 1.4 7.7 9.3 4.2 6.1 9.3 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TACC_C PF05010.14 KNZ75165.1 - 1.6 8.5 12.4 2.1 8.1 0.1 2.1 1 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SF1-HH PF16275.5 KNZ75165.1 - 2.3 8.6 7.6 2 8.7 1.0 2.6 1 1 1 2 2 2 0 Splicing factor 1 helix-hairpin domain FUSC PF04632.12 KNZ75165.1 - 7.9 4.9 6.1 9.7 4.6 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WLM PF08325.10 KNZ75166.1 - 4.6e-38 131.2 0.7 4.6e-38 131.2 0.7 1.7 2 0 0 2 2 2 1 WLM domain ubiquitin PF00240.23 KNZ75166.1 - 5.9e-08 32.4 0.0 1.2e-06 28.1 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 KNZ75166.1 - 0.0044 16.9 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain HD_2 PF12917.7 KNZ75166.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Zincin_1 PF06262.11 KNZ75166.1 - 0.088 12.9 0.1 0.42 10.8 0.1 2.1 1 1 1 2 2 2 0 Zincin-like metallopeptidase DNA_pol_delta_4 PF04081.13 KNZ75167.1 - 1.4e-29 103.1 3.1 1.4e-29 103.1 0.1 1.9 1 1 1 2 2 2 1 DNA polymerase delta, subunit 4 Rhabdo_matrix PF03397.14 KNZ75167.1 - 0.17 11.6 1.2 0.75 9.5 0.4 1.9 1 1 1 2 2 2 0 Rhabdovirus matrix protein FAD_binding_3 PF01494.19 KNZ75169.1 - 4.6e-91 305.7 0.0 5.9e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KNZ75169.1 - 1.1e-32 113.4 0.1 2.1e-32 112.5 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 KNZ75169.1 - 2.5e-05 23.2 0.6 3.8e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KNZ75169.1 - 3.9e-05 23.8 0.3 0.00022 21.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KNZ75169.1 - 8.9e-05 21.7 1.7 0.00014 21.1 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KNZ75169.1 - 0.00025 21.1 0.1 0.032 14.2 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KNZ75169.1 - 0.0007 18.9 0.3 0.0031 16.8 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ75169.1 - 0.00074 18.9 2.0 0.004 16.5 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KNZ75169.1 - 0.00084 18.7 0.2 0.0016 17.8 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KNZ75169.1 - 0.0027 17.4 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ75169.1 - 0.0033 16.7 0.1 0.0063 15.8 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KNZ75169.1 - 0.0079 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_oxidored PF12831.7 KNZ75169.1 - 0.011 15.1 2.0 0.021 14.2 2.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KNZ75169.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.22 KNZ75169.1 - 0.013 14.6 0.1 0.021 14.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KNZ75169.1 - 0.029 13.4 1.4 0.051 12.6 1.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KNZ75169.1 - 0.11 13.0 0.0 0.28 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 KNZ75169.1 - 0.12 12.9 0.2 0.55 10.8 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KNZ75169.1 - 0.13 11.8 0.4 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UCH PF00443.29 KNZ75170.1 - 6.5e-56 189.7 0.0 1e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ75170.1 - 3.7e-22 79.3 0.5 2.3e-21 76.7 0.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KNZ75170.1 - 1.6e-07 31.8 0.0 3.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DUF668 PF05003.12 KNZ75170.1 - 0.049 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) zf-MIZ PF02891.20 KNZ75170.1 - 0.052 13.3 0.8 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RanBP PF00641.18 KNZ75170.1 - 1.4 8.3 4.0 0.59 9.5 0.4 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others ADIP PF11559.8 KNZ75171.1 - 3e-23 82.6 3.9 3e-23 82.6 3.9 3.6 3 1 1 4 4 4 2 Afadin- and alpha -actinin-Binding BAR_3 PF16746.5 KNZ75171.1 - 0.0046 16.7 0.4 0.0046 16.7 0.4 3.2 2 1 0 2 2 2 2 BAR domain of APPL family HIF-1a_CTAD PF08778.10 KNZ75171.1 - 0.081 12.6 0.2 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain AIP3 PF03915.13 KNZ75171.1 - 2.7 7.0 15.0 1.5 7.8 5.0 2.3 2 0 0 2 2 2 0 Actin interacting protein 3 TPR_MLP1_2 PF07926.12 KNZ75171.1 - 3 7.9 26.8 0.59 10.2 5.5 3.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein zf-HC5HC2H_2 PF13832.6 KNZ75172.1 - 1.1e-16 60.9 2.9 1.1e-16 60.9 2.9 4.5 4 1 0 4 4 4 2 PHD-zinc-finger like domain PHD PF00628.29 KNZ75172.1 - 1.5e-13 50.4 51.8 2.6e-09 36.8 9.6 6.0 6 0 0 6 6 6 3 PHD-finger BAH PF01426.18 KNZ75172.1 - 2.9e-13 49.7 0.0 6.5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KNZ75172.1 - 8.1e-13 48.4 1.7 8.1e-13 48.4 1.7 5.0 4 2 0 4 4 4 2 PHD-like zinc-binding domain PHD_2 PF13831.6 KNZ75172.1 - 0.00044 19.7 2.4 0.00044 19.7 2.4 6.2 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.22 KNZ75172.1 - 0.0064 16.4 5.0 0.0064 16.4 5.0 6.5 6 1 1 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) AT_hook PF02178.19 KNZ75172.1 - 0.051 13.5 2.6 0.13 12.2 2.6 1.8 1 0 0 1 1 1 0 AT hook motif HATPase_c PF02518.26 KNZ75173.1 - 4.8e-23 81.8 0.0 1.1e-22 80.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KNZ75173.1 - 4.7e-18 65.4 0.0 3.7e-10 40.0 0.0 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c_3 PF13589.6 KNZ75173.1 - 0.081 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ran_BP1 PF00638.18 KNZ75174.1 - 1.1e-15 58.0 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Phage_holin_T PF11031.8 KNZ75174.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T holin Glycos_transf_2 PF00535.26 KNZ75175.1 - 3.4e-21 75.8 0.0 4.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KNZ75175.1 - 5.9e-09 36.2 0.0 1.1e-08 35.2 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KNZ75175.1 - 0.02 15.4 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 KNZ75175.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.4 2 0 0 2 2 2 0 Glycosyltransferase like family 2 CBM_1 PF00734.18 KNZ75177.1 - 1.1e-07 31.7 11.3 1.1e-07 31.7 11.3 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF1604 PF07713.13 KNZ75178.1 - 5.8e-40 135.0 0.7 5.8e-40 135.0 0.7 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KNZ75178.1 - 3.6e-07 29.9 1.1 3.5e-05 23.6 0.4 2.9 2 0 0 2 2 2 2 G-patch domain WD40 PF00400.32 KNZ75179.1 - 3.9e-14 52.8 2.9 3.3e-06 27.7 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75179.1 - 0.00056 20.2 0.1 0.29 11.4 0.0 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain FKBP_C PF00254.28 KNZ75179.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase NOA36 PF06524.12 KNZ75179.1 - 0.44 9.8 4.1 0.62 9.3 4.1 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_A_exo1 PF01612.20 KNZ75180.1 - 5.6e-06 26.2 0.2 1.8e-05 24.5 0.2 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Amidase PF01425.21 KNZ75181.1 - 4e-68 230.4 3.4 4.8e-68 230.2 3.4 1.0 1 0 0 1 1 1 1 Amidase RhoGEF PF00621.20 KNZ75187.1 - 8.1e-62 208.7 0.2 2e-33 116.2 0.1 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KNZ75187.1 - 1.4e-60 205.3 0.0 2.2e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KNZ75187.1 - 8.1e-16 58.3 0.0 2.3e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 KNZ75187.1 - 3e-05 24.0 0.0 7.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KNZ75187.1 - 0.00074 20.0 0.0 0.004 17.7 0.0 2.3 1 1 0 1 1 1 1 PH domain F-box PF00646.33 KNZ75188.1 - 7e-06 25.8 0.2 1.9e-05 24.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ75188.1 - 0.014 15.3 0.1 0.053 13.4 0.2 2.0 2 0 0 2 2 2 0 F-box-like BIR PF00653.21 KNZ75189.1 - 2.7e-34 117.7 1.5 5.8e-18 65.3 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 KNZ75189.1 - 4.5e-05 23.5 0.0 0.046 13.8 0.0 2.6 2 0 0 2 2 2 2 C3HC zinc finger-like WAPL PF07814.13 KNZ75190.1 - 4.4e-15 55.4 0.1 1.6e-11 43.6 0.0 3.2 3 0 0 3 3 3 3 Wings apart-like protein regulation of heterochromatin rRNA_proc-arch PF13234.6 KNZ75191.1 - 8.5e-77 258.7 0.0 1.7e-76 257.8 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KNZ75191.1 - 1.8e-49 167.5 0.1 4.1e-49 166.4 0.1 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KNZ75191.1 - 8e-18 64.8 0.0 3.1e-17 62.9 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ75191.1 - 7.9e-07 29.4 0.0 7.9e-06 26.2 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ75191.1 - 1.6e-05 25.0 0.0 3.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KNZ75191.1 - 0.016 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 KNZ75191.1 - 0.055 13.8 0.0 0.59 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DBINO PF13892.6 KNZ75191.1 - 0.066 13.6 1.2 0.22 11.9 1.2 1.8 1 0 0 1 1 1 0 DNA-binding domain ATPase_2 PF01637.18 KNZ75191.1 - 0.67 9.8 2.8 1 9.2 0.0 2.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AA_permease PF00324.21 KNZ75192.1 - 1.5e-121 406.4 37.4 1.8e-121 406.1 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ75192.1 - 6.7e-35 120.7 42.8 8e-35 120.5 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_23 PF13489.6 KNZ75193.1 - 1.7e-13 50.7 0.0 2.9e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ75193.1 - 7.4e-12 45.8 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ75193.1 - 4e-11 43.5 0.0 8.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ75193.1 - 2.3e-10 41.0 0.0 5.2e-10 39.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ75193.1 - 8.8e-07 28.8 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KNZ75193.1 - 0.0021 18.0 0.0 0.062 13.1 0.0 2.2 1 1 1 2 2 2 1 Hypothetical methyltransferase NNMT_PNMT_TEMT PF01234.17 KNZ75193.1 - 0.018 14.2 0.0 0.036 13.2 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 KNZ75193.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 KNZ75193.1 - 0.035 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 KNZ75193.1 - 0.1 13.6 0.0 0.2 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RhoGEF PF00621.20 KNZ75194.1 - 1.3e-59 201.5 0.2 3.5e-29 102.3 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.22 KNZ75194.1 - 4.1e-58 197.2 0.0 6.4e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KNZ75194.1 - 7e-19 68.3 0.0 2.3e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.21 KNZ75194.1 - 0.00032 20.7 0.0 0.00069 19.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.29 KNZ75194.1 - 0.01 16.4 0.0 0.033 14.7 0.0 2.0 1 0 0 1 1 1 0 PH domain CEP209_CC5 PF16574.5 KNZ75196.1 - 0.051 13.7 3.0 0.074 13.2 3.0 1.2 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 RGCC PF15151.6 KNZ75197.1 - 0.22 11.7 3.0 0.29 11.4 3.0 1.1 1 0 0 1 1 1 0 Response gene to complement 32 protein family RNase_H PF00075.24 KNZ75199.1 - 0.0031 17.7 0.0 0.0067 16.6 0.0 1.5 1 1 1 2 2 2 1 RNase H Herpes_Helicase PF02689.14 KNZ75201.1 - 2.7e-05 22.3 0.0 2.8e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ75201.1 - 0.067 13.0 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ75202.1 - 1.2e-33 116.8 0.0 1.4e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ75202.1 - 0.0037 16.9 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Chitin_synth_1 PF01644.17 KNZ75203.1 - 6.9e-80 266.7 0.1 1.2e-79 265.9 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KNZ75203.1 - 1.7e-28 98.3 0.0 3.6e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KNZ75203.1 - 1.4e-24 86.6 0.6 1.9e-18 66.4 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KNZ75203.1 - 0.0019 18.2 13.4 0.02 14.8 13.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 adh_short PF00106.25 KNZ75204.1 - 8e-38 129.9 0.0 1e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ75204.1 - 5.4e-26 91.6 0.0 6.9e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ75204.1 - 1.9e-10 41.0 0.0 3.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KNZ75204.1 - 1.6e-05 24.2 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KNZ75204.1 - 4.9e-05 22.9 0.0 0.00016 21.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ75204.1 - 0.00019 21.4 0.1 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KNZ75204.1 - 0.039 13.1 0.1 0.1 11.8 0.1 1.7 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.13 KNZ75204.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 KNZ75204.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PIF1 PF05970.14 KNZ75205.1 - 1.9e-54 185.2 0.8 1.5e-32 113.2 0.1 2.0 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KNZ75205.1 - 0.0018 18.1 0.0 0.006 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ75205.1 - 0.013 15.3 0.2 0.057 13.2 0.1 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ75205.1 - 0.03 14.3 0.0 0.095 12.7 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KNZ75205.1 - 0.043 14.2 0.5 0.52 10.7 0.1 2.7 1 1 1 2 2 2 0 RNA helicase PhoH PF02562.16 KNZ75205.1 - 0.11 11.9 0.0 0.48 9.8 0.0 1.9 1 1 1 2 2 2 0 PhoH-like protein NMO PF03060.15 KNZ75210.1 - 3.4e-31 108.9 3.1 1.3e-29 103.7 3.1 2.1 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KNZ75210.1 - 7.7e-06 25.2 0.6 1.2e-05 24.6 0.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 KNZ75210.1 - 0.055 12.9 0.7 0.22 10.9 0.1 1.8 2 1 0 2 2 2 0 Histidine biosynthesis protein IMPDH PF00478.25 KNZ75210.1 - 0.063 12.3 0.7 0.15 11.1 0.2 1.9 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KNZ75210.1 - 0.099 11.8 5.4 0.72 8.9 5.4 2.0 1 1 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 KNZ75210.1 - 0.12 11.6 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ADH_zinc_N PF00107.26 KNZ75211.1 - 1.3e-21 76.9 0.0 2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ75211.1 - 3.7e-10 39.7 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KNZ75211.1 - 1.4e-06 29.4 0.0 2.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 KNZ75211.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Retrotrans_gag PF03732.17 KNZ75212.1 - 0.0012 19.1 0.1 0.0027 18.0 0.0 1.7 1 1 1 2 2 2 1 Retrotransposon gag protein WYL_3 PF18488.1 KNZ75212.1 - 0.061 13.7 1.0 0.19 12.1 0.0 2.2 3 0 0 3 3 3 0 WYL domain 7TM_GPCR_Srab PF10292.9 KNZ75213.1 - 0.37 9.7 7.2 0.37 9.6 6.3 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor PIF1 PF05970.14 KNZ75214.1 - 2.9e-39 135.3 0.1 3.2e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ75214.1 - 0.006 16.3 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain Exo_endo_phos_2 PF14529.6 KNZ75215.1 - 1.7e-05 24.6 0.1 3.3e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KNZ75215.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 KNZ75217.1 - 5.3e-05 23.9 3.9 5.3e-05 23.9 3.9 1.3 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.22 KNZ75218.1 - 3.7e-83 279.8 0.0 4.4e-83 279.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_15 PF00723.21 KNZ75219.1 - 2.6e-41 141.9 0.0 2.3e-22 79.4 0.0 3.6 3 1 0 3 3 3 3 Glycosyl hydrolases family 15 FAD_binding_4 PF01565.23 KNZ75220.1 - 2.5e-11 43.5 0.2 1.2e-10 41.3 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain ALO PF04030.14 KNZ75220.1 - 2.4e-08 34.1 0.2 1.2e-07 31.8 0.2 2.2 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Clat_adaptor_s PF01217.20 KNZ75221.1 - 7.3e-49 165.4 1.7 9.7e-49 165.0 1.7 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain F-box PF00646.33 KNZ75222.1 - 0.096 12.6 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 F-box domain CsbD PF05532.12 KNZ75223.1 - 1.2e-10 41.1 7.4 2.8e-10 39.9 2.8 2.2 1 1 1 2 2 2 2 CsbD-like GMC_oxred_N PF00732.19 KNZ75224.1 - 2.7e-57 194.4 0.0 3.6e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ75224.1 - 1.5e-33 116.4 0.0 2.8e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KNZ75224.1 - 0.00012 21.3 0.0 0.0014 17.8 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KNZ75224.1 - 0.012 14.9 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ75224.1 - 0.046 13.9 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KNZ75224.1 - 0.082 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF1582 PF07621.11 KNZ75224.1 - 0.25 11.3 1.7 0.28 11.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Zn_clus PF00172.18 KNZ75225.1 - 0.32 11.1 8.3 2 8.6 0.6 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KNZ75227.1 - 7.4e-35 120.7 10.8 9.1e-27 94.0 9.0 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ75227.1 - 1.4e-20 73.6 12.0 1e-16 60.9 8.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KNZ75227.1 - 0.0014 17.1 0.1 0.0047 15.3 0.0 1.9 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Ndc1_Nup PF09531.10 KNZ75227.1 - 6 5.4 6.7 5.6 5.5 2.9 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_79C PF16862.5 KNZ75228.1 - 1.4e-18 67.7 0.0 6.2e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF5011 PF16403.5 KNZ75228.1 - 0.18 11.9 0.5 0.76 10.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) ThylakoidFormat PF11264.8 KNZ75229.1 - 0.21 11.2 0.1 0.31 10.7 0.1 1.1 1 0 0 1 1 1 0 Thylakoid formation protein DUF2235 PF09994.9 KNZ75231.1 - 4.2e-93 311.8 0.0 7e-93 311.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KNZ75231.1 - 0.11 12.4 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal COG6 PF06419.11 KNZ75233.1 - 5.8e-153 510.4 4.4 5.8e-153 510.4 4.4 1.7 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Prenyltransf PF01255.19 KNZ75234.1 - 1e-70 237.7 0.0 1.3e-70 237.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AP_endonuc_2 PF01261.24 KNZ75234.1 - 0.022 14.2 0.1 0.051 13.0 0.1 1.7 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel CBP PF12192.8 KNZ75236.1 - 3.4e-05 24.0 5.2 3.4e-05 24.0 5.2 2.0 2 0 0 2 2 2 1 Fungal calcium binding protein gag-asp_proteas PF13975.6 KNZ75237.1 - 0.00096 19.7 0.0 0.0021 18.6 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ75237.1 - 0.0063 17.1 0.0 0.0096 16.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 KNZ75239.1 - 4.4e-09 36.1 0.1 8.7e-09 35.2 0.1 1.5 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KNZ75239.1 - 0.038 13.9 0.1 0.061 13.2 0.1 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF2235 PF09994.9 KNZ75241.1 - 4.4e-96 321.6 0.1 6.8e-96 321.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KNZ75241.1 - 0.065 13.1 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal MFS_1 PF07690.16 KNZ75242.1 - 8.2e-17 61.2 32.6 8.2e-17 61.2 32.6 2.0 1 1 2 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ75242.1 - 2.4e-06 26.7 8.0 2.4e-06 26.7 8.0 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter DUF1980 PF09323.10 KNZ75242.1 - 0.0087 16.0 0.5 3.3 7.6 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1980) Abhydrolase_9_N PF15420.6 KNZ75242.1 - 0.18 11.8 6.8 0.076 13.0 0.9 2.7 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Ras PF00071.22 KNZ75243.1 - 3.4e-51 173.1 0.0 3.9e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ75243.1 - 1.1e-21 77.3 0.0 1.4e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ75243.1 - 1.3e-07 31.3 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KNZ75243.1 - 0.0008 19.3 0.0 0.0099 15.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 KNZ75243.1 - 0.0014 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KNZ75243.1 - 0.021 14.9 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KNZ75243.1 - 0.17 11.2 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3445 PF11927.8 KNZ75244.1 - 1.7e-70 237.2 0.0 2.1e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) FAD_binding_3 PF01494.19 KNZ75246.1 - 1.3e-15 57.5 1.0 7.1e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KNZ75246.1 - 0.00035 20.8 0.2 0.00084 19.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KNZ75246.1 - 0.00067 19.7 0.3 0.048 13.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KNZ75246.1 - 0.0022 17.3 1.0 0.0033 16.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ75246.1 - 0.0026 17.4 1.5 0.0084 15.7 0.8 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KNZ75246.1 - 0.0086 15.2 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 KNZ75246.1 - 0.016 14.4 0.4 0.027 13.7 0.4 1.4 1 0 0 1 1 1 0 Thi4 family Kelch_4 PF13418.6 KNZ75247.1 - 1.2e-17 63.6 5.2 0.005 16.8 0.0 6.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ75247.1 - 8.7e-16 57.6 12.7 2e-07 31.1 0.1 6.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KNZ75247.1 - 9.8e-12 44.3 4.9 0.0033 17.0 0.0 6.3 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 KNZ75247.1 - 9.3e-11 41.5 8.1 0.086 12.9 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 KNZ75247.1 - 6.2e-10 39.1 7.0 0.036 14.4 0.0 6.6 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 KNZ75247.1 - 8.1e-10 38.3 7.2 0.00025 20.9 0.0 5.9 5 0 0 5 5 5 1 Kelch motif zf-MYND PF01753.18 KNZ75247.1 - 0.00025 21.1 7.3 0.00055 20.0 7.3 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KNZ75247.1 - 0.0035 17.6 7.9 0.0071 16.6 7.9 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding ANAPC3 PF12895.7 KNZ75247.1 - 0.028 14.7 0.1 0.06 13.6 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KNZ75247.1 - 0.2 12.2 0.1 0.49 10.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HEAT_2 PF13646.6 KNZ75248.1 - 3.2e-08 33.8 2.8 3.1 8.2 0.1 6.6 5 2 1 6 6 6 3 HEAT repeats Adaptin_N PF01602.20 KNZ75248.1 - 3.3e-06 26.0 4.3 0.011 14.3 0.0 3.1 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.6 KNZ75248.1 - 9.1e-05 22.9 16.6 0.086 13.4 0.2 7.7 9 0 0 9 9 9 2 HEAT-like repeat Arm PF00514.23 KNZ75248.1 - 0.0017 18.3 0.7 0.027 14.5 0.2 3.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KNZ75248.1 - 0.0051 16.9 18.5 9.4 6.8 0.0 9.4 12 0 0 12 12 12 2 HEAT repeat MMS19_N PF14500.6 KNZ75248.1 - 0.0053 16.4 3.1 0.12 12.0 0.1 3.6 2 1 1 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II IncE PF17627.2 KNZ75249.1 - 0.074 13.1 1.3 0.42 10.6 0.5 2.3 2 0 0 2 2 2 0 Inclusion membrane protein E DUF2070 PF09843.9 KNZ75249.1 - 0.32 9.2 9.4 0.39 9.0 9.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Stevor PF17410.2 KNZ75249.1 - 1 8.9 3.5 1.6 8.2 3.5 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MAP17 PF15807.5 KNZ75251.1 - 0.00021 21.5 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF1180 PF06679.12 KNZ75251.1 - 0.00076 19.9 11.1 0.00076 19.9 11.1 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1180) TMEM154 PF15102.6 KNZ75251.1 - 0.0011 18.9 0.5 0.0023 17.9 0.5 1.5 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 KNZ75251.1 - 0.0053 17.0 3.2 0.015 15.6 3.2 1.8 1 1 0 1 1 1 1 Glycophorin A HIG_1_N PF04588.13 KNZ75251.1 - 0.071 13.4 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 Hypoxia induced protein conserved region T4SS_CagC PF16943.5 KNZ75251.1 - 0.072 13.3 0.6 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system Saf_2TM PF18303.1 KNZ75251.1 - 0.17 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Amnionless PF14828.6 KNZ75251.1 - 0.3 9.9 1.9 0.45 9.3 1.9 1.2 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 KNZ75251.1 - 0.5 9.9 7.6 0.75 9.3 7.6 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DSPc PF00782.20 KNZ75252.1 - 1.6e-30 105.6 0.0 1.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KNZ75252.1 - 0.00073 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 KNZ75252.1 - 0.01 16.0 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 KNZ75252.1 - 0.052 13.1 0.1 0.096 12.2 0.1 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.14 KNZ75252.1 - 0.09 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Glyco_hydro_61 PF03443.14 KNZ75253.1 - 1.6e-45 155.6 0.0 1.9e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NAD_binding_4 PF07993.12 KNZ75254.1 - 1.2e-24 86.9 0.0 1.9e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ75254.1 - 9.8e-11 40.9 0.0 9.2e-08 31.1 0.0 3.2 2 1 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KNZ75254.1 - 1.1e-07 31.5 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensin2nSMC PF12422.8 KNZ75254.1 - 0.042 14.0 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit ANAPC2 PF08672.11 KNZ75254.1 - 0.078 13.5 0.0 1 9.9 0.0 2.9 2 1 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Aldo_ket_red PF00248.21 KNZ75255.1 - 2.6e-35 122.1 0.0 1.1e-32 113.4 0.0 2.5 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 KNZ75256.1 - 1.3e-26 93.4 39.8 1.4e-24 86.7 31.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KNZ75256.1 - 3.3e-05 23.4 24.7 0.00025 20.5 24.7 2.3 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB BAG PF02179.16 KNZ75257.1 - 1.1e-06 29.0 1.6 3.3e-06 27.4 1.6 1.8 1 0 0 1 1 1 1 BAG domain DUF4637 PF15470.6 KNZ75257.1 - 7.9 6.2 7.5 86 2.8 7.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PBP PF01161.20 KNZ75258.1 - 7.6e-10 39.2 0.1 9.8e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase_Tyr PF07714.17 KNZ75259.1 - 1.9e-69 233.8 0.0 1.2e-32 113.3 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 KNZ75259.1 - 1.7e-58 198.1 0.0 2.8e-32 112.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Kdo PF06293.14 KNZ75259.1 - 2.7e-06 26.9 0.0 1.2 8.5 0.0 3.4 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ75259.1 - 0.0003 20.2 0.0 0.84 8.9 0.0 3.2 3 0 0 3 3 3 1 Kinase-like RIO1 PF01163.22 KNZ75259.1 - 0.00086 19.0 0.4 7.1 6.2 0.0 4.5 4 1 1 5 5 5 2 RIO1 family TraI PF07057.11 KNZ75259.1 - 0.003 17.7 0.0 0.062 13.4 0.0 2.9 3 0 0 3 3 3 1 DNA helicase TraI Pkinase_fungal PF17667.1 KNZ75259.1 - 0.034 12.9 0.0 14 4.4 0.0 3.0 3 0 0 3 3 3 0 Fungal protein kinase APH PF01636.23 KNZ75259.1 - 0.039 13.9 0.6 1.1 9.1 0.0 3.5 5 0 0 5 5 5 0 Phosphotransferase enzyme family DUF4139 PF13598.6 KNZ75260.1 - 1.7e-48 165.1 0.0 1.2e-47 162.3 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KNZ75260.1 - 1.4e-23 83.2 0.5 1.4e-23 83.2 0.5 3.3 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) Prefoldin_2 PF01920.20 KNZ75260.1 - 0.011 15.7 6.0 0.93 9.5 0.3 2.3 2 0 0 2 2 2 0 Prefoldin subunit FapA PF03961.13 KNZ75260.1 - 0.019 13.6 2.0 0.027 13.1 2.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 KNZ75260.1 - 0.034 13.0 3.9 0.052 12.4 3.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PMEI PF04043.15 KNZ75260.1 - 0.041 14.2 0.1 0.081 13.3 0.1 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor TMPIT PF07851.13 KNZ75260.1 - 0.094 11.9 2.3 0.14 11.4 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein Tektin PF03148.14 KNZ75260.1 - 0.1 11.3 3.3 0.22 10.3 3.3 1.4 1 1 0 1 1 1 0 Tektin family Golgin_A5 PF09787.9 KNZ75260.1 - 0.14 11.6 3.0 0.24 10.8 3.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 OmpH PF03938.14 KNZ75260.1 - 0.24 11.8 2.8 4.8 7.5 0.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Cortex-I_coil PF09304.10 KNZ75260.1 - 0.24 11.6 6.3 0.13 12.5 0.4 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil Swi5 PF07061.11 KNZ75260.1 - 0.34 11.0 3.5 0.55 10.3 0.2 2.3 2 0 0 2 2 2 0 Swi5 TPR_MLP1_2 PF07926.12 KNZ75260.1 - 0.37 10.8 4.0 0.94 9.5 0.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 KNZ75260.1 - 0.54 10.6 6.0 1.8 8.9 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 KNZ75260.1 - 0.54 10.8 5.5 0.57 10.8 2.7 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.9 KNZ75260.1 - 0.59 10.2 8.5 4.1 7.4 1.8 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 KNZ75260.1 - 0.64 10.1 3.4 3.5 7.7 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 KNZ75260.1 - 1.4 9.1 4.1 4.1 7.7 4.1 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.9 KNZ75260.1 - 1.5 7.8 5.8 2.3 7.1 5.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Cluap1 PF10234.9 KNZ75260.1 - 1.9 7.8 9.4 4.3 6.6 0.6 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF724 PF05266.14 KNZ75260.1 - 2.6 7.9 5.5 5.7 6.7 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 KNZ75260.1 - 8.2 6.5 9.2 2.4 8.2 1.6 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cu-oxidase PF00394.22 KNZ75261.1 - 2.7e-43 147.9 0.1 4.8e-41 140.5 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ75261.1 - 1.1e-40 138.3 0.7 1.9e-38 131.1 0.3 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ75261.1 - 1.2e-37 128.7 7.4 1.2e-33 115.8 0.3 3.8 3 1 0 3 3 3 3 Multicopper oxidase Chromo PF00385.24 KNZ75263.1 - 9.6e-16 57.4 0.1 1.1e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4140 PF13600.6 KNZ75264.1 - 1.2e-19 70.6 0.0 1.5e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4139 PF13598.6 KNZ75264.1 - 2.6e-19 69.8 0.0 3.8e-18 66.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF5082 PF16888.5 KNZ75264.1 - 0.066 13.5 5.2 1.6 9.0 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 KNZ75264.1 - 0.17 11.8 6.2 3.3 7.7 0.9 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF724 PF05266.14 KNZ75264.1 - 0.8 9.5 3.8 1.6 8.5 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PBP PF01161.20 KNZ75266.1 - 3.3e-10 40.4 0.0 4.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein WD40 PF00400.32 KNZ75267.1 - 1e-137 443.9 75.3 7.2e-12 45.6 0.5 15.3 14 1 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75267.1 - 8.9e-51 170.2 20.4 0.00054 20.2 0.1 13.6 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ75267.1 - 1.6e-20 72.5 1.5 2.2 8.3 0.0 13.2 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KNZ75267.1 - 1.8e-13 49.8 16.7 0.0012 17.5 0.5 6.2 2 2 5 7 7 7 5 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KNZ75267.1 - 4.1e-13 49.0 14.0 0.69 8.8 0.1 10.3 1 1 9 11 11 11 2 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KNZ75267.1 - 2.4e-12 47.1 0.0 4.8e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KNZ75267.1 - 1.7e-11 44.0 2.4 2 7.6 0.0 7.8 2 1 7 10 10 10 3 WD40-like domain AAA_16 PF13191.6 KNZ75267.1 - 4.2e-06 27.3 0.2 6.4e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain nos_propeller PF18764.1 KNZ75267.1 - 8e-05 22.5 2.4 20 5.2 0.0 7.0 8 0 0 8 8 8 0 Nitrous oxide reductase propeller repeat APS_kinase PF01583.20 KNZ75267.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 KNZ75267.1 - 0.0043 17.3 0.7 0.061 13.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF3748 PF12566.8 KNZ75267.1 - 0.0048 16.8 2.9 6.5 6.7 0.0 5.3 2 1 5 7 7 7 1 Protein of unknown function (DUF3748) NB-ARC PF00931.22 KNZ75267.1 - 0.0072 15.5 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Cadherin_4 PF17803.1 KNZ75267.1 - 0.016 15.8 5.8 52 4.6 0.0 6.1 4 2 0 4 4 4 0 Bacterial cadherin-like domain AAA_30 PF13604.6 KNZ75267.1 - 0.023 14.4 0.1 0.49 10.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 KNZ75267.1 - 0.024 14.4 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 KNZ75267.1 - 0.024 15.0 0.1 0.13 12.7 0.1 2.3 1 1 0 1 1 1 0 RNA helicase DUF4988 PF16378.5 KNZ75267.1 - 0.028 14.1 2.7 1.6 8.4 0.1 3.8 2 2 1 4 4 4 0 Domain of unknown function Zeta_toxin PF06414.12 KNZ75267.1 - 0.13 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Proteasome_A_N PF10584.9 KNZ75267.1 - 0.21 11.3 12.6 54 3.6 0.0 7.7 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature ComS PF17584.2 KNZ75267.1 - 4.5 6.9 7.9 71 3.0 0.1 5.1 5 0 0 5 5 5 0 Bacillus competence protein S UPF0147 PF03685.13 KNZ75270.1 - 0.085 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Chromo PF00385.24 KNZ75272.1 - 6.7e-16 57.9 0.1 8.3e-16 57.6 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CALCOCO1 PF07888.11 KNZ75273.1 - 0.02 13.8 1.5 0.027 13.4 1.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DNA_pol3_delt_C PF14840.6 KNZ75273.1 - 0.1 13.0 0.4 0.22 11.8 0.2 1.6 1 1 1 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term PCNA_C PF02747.15 KNZ75274.1 - 3.7e-14 53.0 0.1 5.3e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain TolA PF06519.11 KNZ75274.1 - 0.0004 20.5 0.3 0.00067 19.8 0.3 1.4 1 0 0 1 1 1 1 TolA C-terminal PCNA_N PF00705.18 KNZ75274.1 - 0.019 14.7 0.4 0.043 13.5 0.1 1.8 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain Hus1 PF04005.12 KNZ75274.1 - 0.03 13.5 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein WD40 PF00400.32 KNZ75275.1 - 2.6e-147 474.3 78.3 7.3e-12 45.6 0.5 14.9 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75275.1 - 1.6e-48 162.9 21.7 0.00014 22.1 0.2 13.9 1 1 13 14 14 14 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ75275.1 - 1.2e-22 79.3 3.1 3.9 7.5 0.0 14.3 14 0 0 14 14 14 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KNZ75275.1 - 5e-13 48.3 17.0 0.0011 17.5 0.5 6.2 1 1 4 7 7 7 5 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KNZ75275.1 - 3.2e-11 42.8 15.2 0.87 8.5 0.1 10.7 2 1 11 13 13 13 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KNZ75275.1 - 3.6e-11 43.3 0.1 7.9e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KNZ75275.1 - 2.2e-10 40.4 0.9 2 7.7 0.0 7.6 3 2 7 10 10 10 2 WD40-like domain Ricin_B_lectin PF00652.22 KNZ75275.1 - 5.1e-07 30.0 4.9 0.039 14.2 0.0 4.2 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain AAA_16 PF13191.6 KNZ75275.1 - 0.00031 21.2 0.3 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF4988 PF16378.5 KNZ75275.1 - 0.00098 18.8 2.3 1.6 8.4 0.1 4.3 2 2 3 6 6 6 1 Domain of unknown function nos_propeller PF18764.1 KNZ75275.1 - 0.00099 19.0 3.5 54 3.8 0.0 7.9 10 0 0 10 10 10 0 Nitrous oxide reductase propeller repeat APS_kinase PF01583.20 KNZ75275.1 - 0.0071 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 KNZ75275.1 - 0.0081 16.4 0.1 0.031 14.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 KNZ75275.1 - 0.017 15.5 0.5 0.1 13.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Tricorn_C1 PF14684.6 KNZ75275.1 - 0.041 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Tricorn protease C1 domain Proteasome_A_N PF10584.9 KNZ75275.1 - 0.045 13.4 8.7 55 3.6 0.0 7.2 8 0 0 8 8 7 0 Proteasome subunit A N-terminal signature AAA_29 PF13555.6 KNZ75275.1 - 0.051 13.3 0.0 0.24 11.2 0.0 2.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 KNZ75275.1 - 0.077 13.4 1.1 0.76 10.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KNZ75275.1 - 0.084 12.4 0.0 0.37 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 KNZ75275.1 - 0.097 12.1 1.0 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 KNZ75275.1 - 0.11 13.0 0.4 0.57 10.7 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 KNZ75275.1 - 0.11 11.7 0.0 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 KNZ75275.1 - 0.27 11.7 9.4 4.4 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ComS PF17584.2 KNZ75275.1 - 0.8 9.3 7.8 63 3.2 0.1 5.2 5 0 0 5 5 5 0 Bacillus competence protein S RNase_H PF00075.24 KNZ75276.1 - 1.6e-05 25.1 0.0 5.1e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 RNase H CDC50 PF03381.15 KNZ75277.1 - 0.049 13.2 0.2 0.057 12.9 0.2 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Retrotrans_gag PF03732.17 KNZ75280.1 - 0.014 15.6 0.8 0.034 14.4 0.1 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein PS_Dcarbxylase PF02666.15 KNZ75281.1 - 2.4e-58 197.0 0.0 4e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KNZ75281.1 - 6.9e-35 119.4 0.0 6.8e-20 71.3 0.1 2.6 2 0 0 2 2 2 2 C2 domain SR-25 PF10500.9 KNZ75281.1 - 1.8 8.1 5.4 1.1 8.8 0.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4430 PF14478.6 KNZ75282.1 - 0.00018 22.0 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4430) IDO PF01231.18 KNZ75284.1 - 3.4e-130 434.7 0.0 4.4e-130 434.3 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 KNZ75284.1 - 0.025 13.4 0.0 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) RVT_3 PF13456.6 KNZ75285.1 - 0.0028 17.4 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like G-alpha PF00503.20 KNZ75286.1 - 5.4e-88 295.5 0.0 2.1e-87 293.6 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ75286.1 - 6.1e-06 25.8 0.4 1.6 8.1 0.0 3.7 4 0 0 4 4 4 3 ADP-ribosylation factor family DUF815 PF05673.13 KNZ75286.1 - 0.0024 17.1 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TniB PF05621.11 KNZ75286.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_29 PF13555.6 KNZ75286.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Asp_protease_2 PF13650.6 KNZ75287.1 - 0.00018 22.0 0.0 0.00027 21.5 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ75287.1 - 0.00028 21.4 0.0 0.00037 21.0 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cyclophil_like2 PF18050.1 KNZ75287.1 - 0.092 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Cyclophilin-like family NAD_binding_4 PF07993.12 KNZ75290.1 - 5e-34 117.6 0.0 7.3e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ75290.1 - 2.6e-26 92.2 0.0 4.2e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KNZ75290.1 - 2.3e-05 24.0 0.0 4.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KNZ75290.1 - 0.0044 17.3 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site VWA PF00092.28 KNZ75291.1 - 1.2e-05 25.7 0.0 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KNZ75291.1 - 0.07 13.2 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus Copine PF07002.16 KNZ75291.1 - 0.14 11.5 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Copine RNA12 PF10443.9 KNZ75292.1 - 1.3e-108 363.6 0.0 3.2e-61 207.4 0.0 2.2 1 1 1 2 2 2 2 RNA12 protein AAA_16 PF13191.6 KNZ75292.1 - 1.9e-05 25.1 0.7 0.00014 22.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 KNZ75292.1 - 5.1e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KNZ75292.1 - 0.0042 17.4 0.0 0.12 12.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain Pdase_M17_N2 PF18295.1 KNZ75292.1 - 0.014 15.7 0.2 0.04 14.2 0.2 1.8 1 0 0 1 1 1 0 M17 aminopeptidase N-terminal domain 2 cobW PF02492.19 KNZ75292.1 - 0.022 14.4 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RRM_1 PF00076.22 KNZ75292.1 - 0.026 14.3 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 KNZ75292.1 - 0.084 13.3 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KNZ75292.1 - 0.097 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF974 PF06159.13 KNZ75293.1 - 7.1e-78 261.8 0.0 9.1e-78 261.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) V-ATPase_H_N PF03224.14 KNZ75294.1 - 1.3e-86 290.8 1.2 1.3e-86 290.8 1.2 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KNZ75294.1 - 5.6e-43 145.8 3.3 3.1e-42 143.4 0.1 2.9 3 0 0 3 3 3 1 V-ATPase subunit H HEAT PF02985.22 KNZ75294.1 - 4.2e-05 23.4 2.4 0.15 12.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Arm_2 PF04826.13 KNZ75294.1 - 9e-05 22.0 0.1 0.00074 19.0 0.0 2.3 1 1 1 2 2 2 1 Armadillo-like HEAT_2 PF13646.6 KNZ75294.1 - 0.014 15.7 1.4 0.31 11.4 0.0 3.4 2 2 0 3 3 3 0 HEAT repeats MRP-L46 PF11788.8 KNZ75295.1 - 5.9e-20 72.2 0.1 2.5e-19 70.2 0.1 2.0 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KNZ75295.1 - 1.3e-08 35.0 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Endonuclease_NS PF01223.23 KNZ75296.1 - 1.5e-59 201.6 0.0 1.9e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.22 KNZ75297.1 - 4.3e-12 45.8 1.3 4.9e-12 45.6 0.2 1.7 2 0 0 2 2 2 1 R3H domain RRM_1 PF00076.22 KNZ75297.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 KNZ75298.1 - 4.9e-42 142.9 0.0 6e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KNZ75298.1 - 0.0001 22.6 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KNZ75298.1 - 0.054 13.2 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B EF-hand_4 PF12763.7 KNZ75299.1 - 7.4e-32 109.4 0.0 4.1e-13 49.2 0.0 3.5 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KNZ75299.1 - 2.2e-08 34.4 0.3 7.2e-05 23.2 0.0 4.3 5 0 0 5 5 4 1 EF-hand domain pair UBA PF00627.31 KNZ75299.1 - 1.5e-05 24.7 0.1 3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain ATG16 PF08614.11 KNZ75299.1 - 0.0033 17.7 8.5 0.0033 17.7 8.5 3.3 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) EF-hand_6 PF13405.6 KNZ75299.1 - 0.0034 17.2 4.1 4.7 7.4 0.0 5.1 6 0 0 6 6 5 1 EF-hand domain EF-hand_1 PF00036.32 KNZ75299.1 - 0.0034 16.8 5.6 0.37 10.4 0.1 5.4 6 0 0 6 6 6 1 EF hand WEMBL PF05701.11 KNZ75299.1 - 0.026 13.2 32.5 0.043 12.5 32.5 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light HBS1_N PF08938.10 KNZ75299.1 - 0.034 14.5 0.0 0.16 12.3 0.0 2.2 1 0 0 1 1 1 0 HBS1 N-terminus UBA_3 PF09288.10 KNZ75299.1 - 0.046 13.5 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain EF-hand_8 PF13833.6 KNZ75299.1 - 0.3 11.0 0.8 27 4.7 0.0 3.9 5 0 0 5 5 5 0 EF-hand domain pair Macoilin PF09726.9 KNZ75299.1 - 0.32 9.5 17.0 0.68 8.4 17.0 1.4 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 KNZ75299.1 - 1.5 9.3 40.2 4.1 8.0 5.7 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region PRKG1_interact PF15898.5 KNZ75299.1 - 1.7 9.6 26.4 6 7.8 11.4 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 KNZ75299.1 - 1.8 6.0 27.6 2.5 5.5 27.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 KNZ75299.1 - 2.1 7.1 35.0 0.55 9.0 10.8 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KNZ75299.1 - 2.5 8.7 30.7 0.12 12.9 9.5 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 KNZ75299.1 - 3.5 7.8 33.1 0.43 10.7 11.2 3.3 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.19 KNZ75299.1 - 5 4.9 14.2 7.4 4.3 14.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 KNZ75299.1 - 6 6.9 39.4 0.2 11.7 21.4 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2420 PF10336.9 KNZ75300.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) 5_nucleotid_C PF02872.18 KNZ75302.1 - 2.9e-26 92.6 0.0 5.2e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 KNZ75302.1 - 1.3e-08 35.6 0.1 2.1e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Bmt2 PF11968.8 KNZ75303.1 - 5e-35 121.3 0.0 6.5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Tetraspanin PF00335.20 KNZ75305.1 - 0.00068 19.4 12.4 0.001 18.8 12.4 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.6 KNZ75305.1 - 1.7 8.0 0.0 1.7 8.0 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) MBF1 PF08523.10 KNZ75306.1 - 4.3e-23 81.5 3.4 7.3e-23 80.8 3.0 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KNZ75306.1 - 1.3e-12 47.6 0.1 2.3e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KNZ75306.1 - 2.5e-05 24.6 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 KNZ75306.1 - 0.0033 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 KNZ75306.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.25 KNZ75307.1 - 3.5e-71 239.5 0.0 7.6e-71 238.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KNZ75307.1 - 8.7e-47 158.4 0.5 1.6e-46 157.6 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KNZ75307.1 - 0.001 19.3 0.0 0.0043 17.3 0.0 2.0 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KNZ75307.1 - 0.0042 16.8 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Alpha-amylase PF00128.24 KNZ75308.1 - 8.8e-51 173.4 0.1 1.4e-50 172.8 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KNZ75308.1 - 1.6e-13 50.7 0.0 3.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Sugar_tr PF00083.24 KNZ75309.1 - 7.2e-77 259.2 19.8 9e-77 258.8 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ75309.1 - 6.9e-16 58.1 32.6 6.9e-16 58.1 32.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 KNZ75309.1 - 0.037 13.9 2.2 0.082 12.8 2.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain BRI3BP PF14965.6 KNZ75309.1 - 2 7.9 7.1 0.59 9.6 2.6 2.2 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Not1 PF04054.15 KNZ75310.1 - 2.9e-124 414.7 0.0 5.3e-124 413.9 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KNZ75310.1 - 2.3e-92 308.4 0.3 4.9e-90 300.8 0.1 2.6 2 0 0 2 2 2 2 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KNZ75310.1 - 1.5e-54 183.9 0.7 1.5e-54 183.9 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KNZ75310.1 - 7.5e-51 172.0 0.0 1.8e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KNZ75310.1 - 9.6e-44 149.1 0.4 2.4e-43 147.8 0.4 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat PDEase_II PF02112.15 KNZ75311.1 - 1.5e-11 44.1 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Peptidase_S9 PF00326.21 KNZ75311.1 - 3.1e-10 39.9 0.0 5.3e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KNZ75311.1 - 6.6e-07 28.8 0.0 0.00025 20.4 0.0 3.1 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 KNZ75311.1 - 0.00012 21.9 0.2 0.00023 20.9 0.2 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 KNZ75311.1 - 0.00044 20.0 0.5 0.0011 18.7 0.4 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B_2 PF12706.7 KNZ75311.1 - 0.00049 19.7 0.0 0.0013 18.2 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_2 PF02230.16 KNZ75311.1 - 0.00082 19.2 0.0 0.54 10.0 0.0 2.8 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Tannase PF07519.11 KNZ75311.1 - 0.016 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase Lactamase_B PF00753.27 KNZ75311.1 - 0.021 14.8 0.1 0.061 13.3 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DLH PF01738.18 KNZ75311.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family 3HBOH PF10605.9 KNZ75311.1 - 0.15 10.3 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) Abhydrolase_6 PF12697.7 KNZ75311.1 - 0.48 11.0 11.6 0.79 10.3 9.2 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Striatin PF08232.12 KNZ75312.1 - 9.1e-52 175.8 8.4 4.3e-50 170.3 0.0 3.2 3 0 0 3 3 3 2 Striatin family WD40 PF00400.32 KNZ75312.1 - 1.8e-37 126.7 3.8 4.2e-07 30.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TMA7 PF09072.10 KNZ75312.1 - 2.4e-12 47.5 17.5 2.4e-12 47.5 17.5 2.1 2 0 0 2 2 2 1 Translation machinery associated TMA7 ANAPC4_WD40 PF12894.7 KNZ75312.1 - 6.4e-12 45.6 0.3 0.018 15.3 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KNZ75312.1 - 0.0015 18.1 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.11 KNZ75312.1 - 0.0023 16.8 0.0 0.74 8.5 0.0 3.0 2 1 1 3 3 3 2 Nup133 N terminal like RNA_pol_Rpc82 PF05645.13 KNZ75314.1 - 7.6e-20 71.8 3.4 1.6e-16 60.9 3.6 2.9 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KNZ75314.1 - 2.5e-17 62.7 0.4 1e-11 44.7 0.2 3.9 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KNZ75314.1 - 5.5e-11 42.3 0.1 2.3e-09 37.0 0.0 3.3 3 0 0 3 3 3 1 TFIIE alpha subunit Metallophos PF00149.28 KNZ75315.1 - 5.8e-11 43.3 0.1 1.1e-10 42.4 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ75315.1 - 3.1e-07 30.7 0.1 1.9e-05 24.9 0.1 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AROS PF15684.5 KNZ75315.1 - 0.034 14.7 0.1 0.055 14.0 0.1 1.2 1 0 0 1 1 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 SPT16 PF08644.11 KNZ75316.1 - 2.7e-55 186.7 0.2 2.1e-54 183.8 0.1 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 KNZ75316.1 - 1.3e-41 142.1 0.0 3.7e-41 140.6 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 KNZ75316.1 - 7.4e-24 84.6 0.0 1.3e-23 83.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KNZ75316.1 - 3.7e-15 56.1 0.3 2.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 KNZ75316.1 - 0.013 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Mannosyl_trans2 PF04188.13 KNZ75317.1 - 1.2e-48 166.6 25.8 2e-48 165.8 25.8 1.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) PvlArgDC PF01862.16 KNZ75318.1 - 0.01 15.7 0.1 0.037 13.8 0.1 1.9 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) TMF_DNA_bd PF12329.8 KNZ75318.1 - 0.4 10.7 5.8 0.79 9.8 5.8 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DEAD PF00270.29 KNZ75320.1 - 2.8e-19 69.5 0.0 5.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ75320.1 - 1.5e-12 47.8 0.0 1.4e-10 41.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 KNZ75320.1 - 2.2e-09 37.9 5.1 7.4e-09 36.2 5.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.15 KNZ75320.1 - 5.9e-09 36.1 0.0 1.3e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KNZ75321.1 - 2.8e-20 72.8 0.0 4.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75321.1 - 1.2e-11 44.4 0.0 6.1e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 KNZ75321.1 - 0.086 13.1 0.0 0.3 11.5 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat NAD_binding_2 PF03446.15 KNZ75322.1 - 6.3e-36 123.9 0.0 9.3e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KNZ75322.1 - 7e-30 103.8 0.0 1.4e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KNZ75322.1 - 0.0056 17.2 0.0 0.021 15.4 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 KNZ75323.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cytochrom_B561 PF03188.16 KNZ75324.1 - 3e-09 37.1 7.3 3e-09 37.1 7.3 1.9 3 0 0 3 3 3 1 Eukaryotic cytochrome b561 Sec7 PF01369.20 KNZ75325.1 - 3e-68 229.1 0.3 5e-68 228.4 0.3 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KNZ75325.1 - 4.3e-18 65.7 0.6 4.3e-18 65.7 0.6 3.0 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KNZ75325.1 - 0.044 13.6 2.9 1.2 9.0 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) Proteasome PF00227.26 KNZ75326.1 - 2e-60 203.6 0.0 3e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KNZ75326.1 - 2.7e-14 52.5 0.3 1.1e-13 50.6 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.13 KNZ75327.1 - 4.4e-46 157.0 0.0 7.7e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 KNZ75327.1 - 0.0036 16.8 0.1 0.0065 15.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family C54 EFG_C PF00679.24 KNZ75327.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus MAT1 PF06391.13 KNZ75328.1 - 9.5e-58 195.4 16.6 1.2e-57 195.1 16.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KNZ75328.1 - 2.4e-22 78.5 7.4 3.9e-22 77.9 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ75328.1 - 5.6e-06 26.1 4.7 1e-05 25.3 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ75328.1 - 3.2e-05 23.7 5.0 7.4e-05 22.5 5.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ75328.1 - 3.3e-05 24.1 6.4 5.4e-05 23.4 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ75328.1 - 5.1e-05 23.0 7.5 0.0001 22.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ75328.1 - 6.9e-05 22.7 6.8 0.00023 21.0 7.0 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ75328.1 - 0.0039 17.2 3.6 0.0049 16.9 2.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KNZ75328.1 - 0.0081 16.4 2.3 0.016 15.5 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KNZ75328.1 - 0.023 14.5 3.8 0.15 11.9 1.2 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KNZ75328.1 - 0.03 14.2 9.0 0.57 10.1 9.4 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 YdjO PF14169.6 KNZ75328.1 - 0.11 12.3 2.2 9.4 6.1 0.0 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.6 KNZ75328.1 - 2.6 8.3 7.5 8.3 6.7 7.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CDC45 PF02724.14 KNZ75328.1 - 6.3 5.0 12.5 8.4 4.6 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LigB PF02900.18 KNZ75329.1 - 6e-37 127.2 0.0 8.1e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.25 KNZ75330.1 - 2.2e-65 220.7 0.0 2.7e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75330.1 - 7.4e-30 104.1 0.0 9.1e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ75330.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like WD40 PF00400.32 KNZ75331.1 - 3.2e-11 43.6 15.1 0.0059 17.4 0.1 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 KNZ75331.1 - 0.015 14.1 1.7 0.13 10.9 0.3 3.1 2 2 2 4 4 4 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 KNZ75331.1 - 0.095 13.0 0.1 17 5.8 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NMO PF03060.15 KNZ75332.1 - 4.2e-42 144.7 0.7 8.9e-42 143.6 0.7 1.6 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 KNZ75332.1 - 2.3e-05 23.6 3.8 3.4e-05 23.0 3.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 KNZ75332.1 - 0.1 11.6 4.6 0.32 10.0 4.6 2.0 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Cyto_heme_lyase PF01265.17 KNZ75333.1 - 8.6e-45 153.6 5.9 5.2e-43 147.7 5.9 2.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.18 KNZ75334.1 - 2.5e-43 148.4 0.3 4.1e-43 147.7 0.0 1.4 2 0 0 2 2 2 1 Brix domain PPL5 PF18168.1 KNZ75334.1 - 0.19 11.0 5.8 0.16 11.2 4.5 1.4 1 1 0 1 1 1 0 Prim-pol family 5 CNDH2_C PF16858.5 KNZ75334.1 - 0.25 11.2 15.5 0.44 10.4 15.5 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Cnd2 PF05786.14 KNZ75334.1 - 1.2 7.7 21.4 1.8 7.1 21.4 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 eIF-3c_N PF05470.12 KNZ75334.1 - 1.4 7.2 15.8 1.9 6.7 15.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SlyX PF04102.12 KNZ75335.1 - 0.0093 16.6 0.0 0.023 15.3 0.0 1.6 2 0 0 2 2 2 1 SlyX TPR_19 PF14559.6 KNZ75336.1 - 5.9e-06 26.7 2.2 0.33 11.5 0.1 5.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75336.1 - 5.9e-06 26.7 15.7 35 5.6 0.0 10.7 9 3 4 13 13 13 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ75336.1 - 1.4e-05 24.8 10.4 1 9.7 0.0 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat Suf PF05843.14 KNZ75336.1 - 1.8e-05 24.9 12.4 0.00057 20.0 0.4 5.6 4 1 1 5 5 5 1 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 KNZ75336.1 - 9.7e-05 22.4 5.4 0.74 9.8 0.2 5.7 4 2 2 6 6 6 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 KNZ75336.1 - 0.00029 21.1 3.3 5 7.5 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ75336.1 - 0.093 13.0 7.5 9.4 6.7 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DALR_1 PF05746.15 KNZ75336.1 - 0.3 11.3 3.7 0.7 10.1 0.0 3.1 3 0 0 3 3 3 0 DALR anticodon binding domain NRDE-2 PF08424.10 KNZ75336.1 - 0.76 8.8 11.6 2.8 7.0 0.2 4.3 4 3 0 4 4 4 0 NRDE-2, necessary for RNA interference TPR_1 PF00515.28 KNZ75336.1 - 1.9 8.4 4.7 57 3.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.22 KNZ75337.1 - 3.5e-43 144.1 23.1 3.1e-09 36.3 1.3 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.6 KNZ75337.1 - 0.055 13.9 3.4 11 6.7 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Lzipper-MIP1 PF14389.6 KNZ75337.1 - 0.073 13.4 0.7 0.22 11.9 0.7 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Piwi PF02171.17 KNZ75338.1 - 4.1e-72 243.0 0.0 6.8e-72 242.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KNZ75338.1 - 8.8e-14 52.3 0.0 2.7e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 KNZ75338.1 - 1e-10 41.7 0.0 3.4e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KNZ75338.1 - 4.1e-09 36.0 0.0 1.1e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KNZ75338.1 - 0.00052 20.2 0.0 0.0024 18.1 0.1 2.1 2 0 0 2 2 2 1 Mid domain of argonaute VASP_tetra PF08776.11 KNZ75338.1 - 0.025 14.2 0.1 0.055 13.1 0.1 1.6 1 0 0 1 1 1 0 VASP tetramerisation domain F_actin_bind PF08919.10 KNZ75338.1 - 0.034 14.2 0.6 0.15 12.2 0.0 2.4 2 0 0 2 2 2 0 F-actin binding Ge1_WD40 PF16529.5 KNZ75338.1 - 0.052 12.5 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Got1 PF04178.12 KNZ75339.1 - 8.7e-24 84.1 19.7 1.5e-23 83.4 19.7 1.4 1 1 0 1 1 1 1 Got1/Sft2-like family HAGH_C PF16123.5 KNZ75340.1 - 1e-19 70.8 0.1 1.7e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 KNZ75340.1 - 2.8e-06 27.5 2.7 5.8e-05 23.2 2.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Adeno_E3_CR2 PF02439.15 KNZ75341.1 - 0.02 14.7 0.2 0.033 14.0 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KNZ75341.1 - 0.055 14.3 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 KNZ75341.1 - 0.056 12.3 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 KNZ75341.1 - 0.074 13.0 0.7 0.12 12.3 0.7 1.3 1 0 0 1 1 1 0 Syndecan domain SRP-alpha_N PF04086.13 KNZ75342.1 - 5e-49 167.8 9.8 6.5e-48 164.1 9.8 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KNZ75342.1 - 4.1e-45 153.8 0.1 3.5e-44 150.8 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KNZ75342.1 - 8.4e-09 35.5 0.0 2.9e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KNZ75342.1 - 3.5e-05 22.9 0.1 8.4e-05 21.7 0.1 1.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB BP28CT PF08146.12 KNZ75342.1 - 0.0014 18.5 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 BP28CT (NUC211) domain AAA_30 PF13604.6 KNZ75342.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 KNZ75342.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 KNZ75342.1 - 0.019 14.7 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 KNZ75342.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 KNZ75342.1 - 0.061 12.5 0.3 1.8 7.6 0.1 2.2 1 1 1 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.15 KNZ75342.1 - 0.11 12.4 0.1 0.45 10.4 0.1 2.0 1 1 0 1 1 1 0 NTPase Cyclin_N PF00134.23 KNZ75343.1 - 2e-08 34.0 0.0 5e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KNZ75343.1 - 0.058 13.8 0.2 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Cyclin C-terminal domain Trans_reg_C PF00486.28 KNZ75344.1 - 0.039 14.0 0.4 0.084 13.0 0.4 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal PC-Esterase PF13839.6 KNZ75345.1 - 6.6e-09 35.9 2.0 1.3e-06 28.4 2.1 2.8 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SOR_SNZ PF01680.17 KNZ75346.1 - 1.7e-111 370.9 4.9 2.4e-111 370.5 4.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 KNZ75346.1 - 2.3e-10 40.2 3.9 1.6e-07 30.9 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KNZ75346.1 - 1.3e-05 24.5 0.4 0.078 12.1 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 KNZ75346.1 - 0.00039 20.5 0.0 0.00095 19.2 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 KNZ75346.1 - 0.0031 17.0 3.7 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase NanE PF04131.14 KNZ75346.1 - 0.0078 15.4 0.4 0.36 10.0 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 KNZ75346.1 - 0.014 14.9 0.5 0.35 10.3 0.0 2.6 2 1 0 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 KNZ75346.1 - 0.036 13.2 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase ThiI PF02568.14 KNZ75346.1 - 0.047 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Milton PF12448.8 KNZ75346.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinesin associated protein Img2 PF05046.14 KNZ75347.1 - 1.1e-22 80.1 0.0 1.4e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Piwi PF02171.17 KNZ75349.1 - 2.9e-56 190.9 0.0 7.8e-56 189.5 0.0 1.6 2 0 0 2 2 2 1 Piwi domain ArgoL1 PF08699.10 KNZ75349.1 - 3.1e-16 58.8 0.1 7.6e-16 57.5 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 KNZ75349.1 - 8e-13 49.2 0.1 1.9e-12 48.0 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KNZ75349.1 - 4.5e-07 29.7 0.0 8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KNZ75349.1 - 2.3e-05 24.6 0.0 7.2e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 KNZ75349.1 - 9.7e-05 22.6 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Ras PF00071.22 KNZ75350.1 - 7.1e-47 159.0 0.5 8.4e-47 158.8 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ75350.1 - 2.2e-22 79.5 0.0 3.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ75350.1 - 6.5e-13 48.5 0.1 7.7e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ75350.1 - 4.9e-06 26.2 0.1 9e-06 25.3 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF3873 PF12989.7 KNZ75350.1 - 0.037 14.4 0.1 0.061 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) SPATA19 PF15212.6 KNZ75350.1 - 0.13 12.4 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial zinc_ribbon_15 PF17032.5 KNZ75351.1 - 0.037 14.8 0.3 0.094 13.5 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon family Zn_clus PF00172.18 KNZ75352.1 - 2e-06 27.8 5.1 2e-06 27.8 5.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.10 KNZ75353.1 - 1.7e-52 178.5 0.2 1.9e-52 178.3 0.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 QCR10 PF09796.9 KNZ75354.1 - 3.5e-19 68.6 0.0 3.8e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) HAD_2 PF13419.6 KNZ75355.1 - 5.6e-07 29.8 0.0 8.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ75355.1 - 9e-05 22.5 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KNZ75355.1 - 0.053 13.8 0.0 0.059 13.6 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 KNZ75356.1 - 6.1e-20 69.2 0.5 5.1e-05 22.5 0.0 5.0 5 1 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 KNZ75356.1 - 1.7e-18 64.9 0.5 0.00012 21.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KNZ75356.1 - 2.4e-17 63.1 0.1 3.6e-07 30.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KNZ75356.1 - 4.2e-15 54.5 2.2 0.00014 21.2 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KNZ75356.1 - 1.3e-11 44.1 1.0 6e-06 26.0 0.1 4.0 4 1 0 4 4 4 2 EF-hand domain pair HHV-5_US34A PF17087.5 KNZ75356.1 - 0.014 15.5 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus US34A protein family EF-hand_9 PF14658.6 KNZ75356.1 - 0.029 14.7 0.0 48 4.4 0.0 3.5 2 1 1 3 3 3 0 EF-hand domain Lambda_tail_I PF06805.12 KNZ75356.1 - 0.05 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I EF-hand_2 PF09068.11 KNZ75356.1 - 0.14 12.3 0.0 17 5.6 0.0 3.1 3 1 1 4 4 4 0 EF hand AMP-binding PF00501.28 KNZ75357.1 - 7.8e-77 258.6 0.0 1.1e-76 258.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ75357.1 - 0.0029 18.5 0.0 0.0071 17.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 KNZ75358.1 - 6.5e-20 71.3 27.3 9.9e-20 70.8 27.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M24 PF00557.24 KNZ75360.1 - 2.9e-45 154.5 0.0 4e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KNZ75360.1 - 0.0034 18.0 0.0 0.0054 17.4 0.0 1.3 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain 2OG-FeII_Oxy_2 PF13532.6 KNZ75361.1 - 3.6e-23 82.8 0.0 5.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UBA PF00627.31 KNZ75361.1 - 0.0003 20.6 0.1 0.00054 19.8 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 KNZ75361.1 - 0.11 12.2 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 CUE domain Peptidase_M13_N PF05649.13 KNZ75362.1 - 9.6e-105 351.4 0.0 1.3e-104 350.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 KNZ75362.1 - 6.9e-59 198.9 0.0 1.1e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Mucin PF01456.17 KNZ75362.1 - 0.00056 19.9 10.5 0.00098 19.1 10.5 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein AJAP1_PANP_C PF15298.6 KNZ75362.1 - 0.021 15.1 7.7 0.054 13.7 7.7 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus IGPD PF00475.18 KNZ75363.1 - 1.6e-57 193.9 0.5 2.4e-57 193.3 0.3 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase SbcCD_C PF13558.6 KNZ75363.1 - 0.062 13.6 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit zf-Mss51 PF13824.6 KNZ75364.1 - 3.9e-23 81.3 15.8 8e-23 80.3 15.8 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Integrin_alpha PF00357.20 KNZ75364.1 - 0.23 11.6 0.9 0.5 10.5 0.9 1.6 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region Lar_restr_allev PF14354.6 KNZ75364.1 - 0.56 10.6 7.8 1.1 9.8 7.8 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar WD40 PF00400.32 KNZ75365.1 - 1.4e-40 136.6 18.2 2.3e-11 44.0 0.3 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75365.1 - 9.5e-13 48.3 1.7 0.0016 18.7 0.0 5.2 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ75365.1 - 4e-08 32.6 2.1 0.071 12.1 0.0 4.4 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KNZ75365.1 - 2e-07 30.1 2.2 0.2 10.2 0.0 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 KNZ75365.1 - 1e-05 25.4 0.2 0.029 14.1 0.0 2.6 2 1 0 2 2 2 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 KNZ75365.1 - 0.00047 19.0 1.9 0.017 13.9 0.1 3.8 2 1 1 4 4 4 1 Nup133 N terminal like Frtz PF11768.8 KNZ75365.1 - 0.0039 15.6 0.0 0.009 14.4 0.0 1.6 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KNZ75365.1 - 0.0051 15.8 1.5 0.014 14.3 0.1 2.3 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 KNZ75365.1 - 0.0097 14.5 0.1 0.56 8.7 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF3642 PF12182.8 KNZ75365.1 - 0.045 14.0 0.0 10 6.5 0.0 2.5 1 1 0 2 2 2 0 Bacterial lipoprotein Chromo PF00385.24 KNZ75366.1 - 2.5e-11 43.3 0.8 3e-11 43.0 0.8 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ75366.1 - 0.049 13.8 0.4 0.07 13.3 0.4 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF647 PF04884.14 KNZ75367.1 - 5.4e-74 248.8 0.6 3.4e-73 246.3 0.4 2.2 2 1 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis Exo_endo_phos PF03372.23 KNZ75367.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Chromo PF00385.24 KNZ75371.1 - 1.3e-14 53.9 0.0 1.4e-14 53.7 0.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RPN7 PF10602.9 KNZ75373.1 - 5e-39 133.8 0.0 9e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KNZ75373.1 - 2.9e-18 66.3 0.1 1.3e-17 64.2 0.1 2.1 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.9 KNZ75373.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 1 DDRGK domain CSN8_PSD8_EIF3K PF10075.9 KNZ75373.1 - 0.023 14.7 0.1 0.072 13.1 0.1 1.8 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 KNZ75373.1 - 0.065 13.4 0.1 1.3 9.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 KNZ75374.1 - 6.8e-22 77.8 0.0 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ75374.1 - 1e-18 67.2 0.0 2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KNZ75374.1 - 1.9e-07 32.2 0.0 4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KNZ75374.1 - 0.079 12.7 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) ThiF PF00899.21 KNZ75376.1 - 2.4e-39 135.2 0.0 8.5e-39 133.4 0.0 1.9 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KNZ75376.1 - 6.9e-05 23.1 2.0 0.0006 20.1 0.8 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 KNZ75376.1 - 0.005 16.7 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KNZ75376.1 - 0.009 16.4 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KNZ75376.1 - 0.027 13.8 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KNZ75376.1 - 0.085 12.4 0.3 0.31 10.6 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 KNZ75376.1 - 0.13 11.4 0.3 0.21 10.8 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 KNZ75376.1 - 0.14 11.7 0.3 0.24 10.9 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NUDIX PF00293.28 KNZ75377.1 - 4.8e-07 29.9 0.0 9.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 KNZ75377.1 - 0.00013 21.9 0.0 0.0032 17.4 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4743) Peroxidase_2 PF01328.17 KNZ75378.1 - 3.4e-50 171.2 0.0 4.6e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 F-box-like PF12937.7 KNZ75379.1 - 4.1e-05 23.4 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF3858 PF12970.7 KNZ75379.1 - 0.076 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) Cys_Met_Meta_PP PF01053.20 KNZ75380.1 - 9.2e-129 429.3 0.0 1e-128 429.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KNZ75380.1 - 9.1e-12 44.8 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNZ75380.1 - 1.1e-08 34.7 0.2 2.4e-08 33.7 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KNZ75380.1 - 1.2e-08 34.3 0.1 2.1e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNZ75380.1 - 6e-06 25.7 0.0 1.1e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KNZ75380.1 - 0.00087 17.9 0.4 0.0018 16.9 0.4 1.6 1 1 0 1 1 1 1 Methionine gamma-lyase BAT PF15915.5 KNZ75380.1 - 0.079 12.8 0.3 0.2 11.5 0.3 1.6 1 0 0 1 1 1 0 GAF and HTH_10 associated domain TNV_CP PF03898.13 KNZ75380.1 - 0.12 11.6 0.3 0.2 10.9 0.3 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein SepSecS PF05889.13 KNZ75380.1 - 0.16 10.7 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS F-box-like PF12937.7 KNZ75381.1 - 4.6e-05 23.2 0.0 0.00016 21.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ75381.1 - 0.0044 16.9 3.0 0.018 14.9 0.2 3.5 4 0 0 4 4 4 1 F-box domain SIR2 PF02146.17 KNZ75382.1 - 1.2e-30 106.8 0.0 3.8e-29 101.9 0.0 2.7 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KNZ75382.1 - 0.0011 18.7 0.0 0.074 12.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zf-RING_7 PF02591.15 KNZ75382.1 - 0.1 12.8 0.4 0.36 11.1 0.1 2.0 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-ribbon_3 PF13248.6 KNZ75382.1 - 0.13 11.7 0.3 0.13 11.7 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain PNTB PF02233.16 KNZ75382.1 - 0.17 10.8 0.0 15 4.4 0.0 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Zn-ribbon_8 PF09723.10 KNZ75382.1 - 0.28 11.3 3.3 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Abhydrolase_4 PF08386.10 KNZ75383.1 - 0.0058 16.7 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.13 KNZ75383.1 - 0.044 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) YkuD_2 PF13645.6 KNZ75383.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Pinin_SDK_memA PF04696.13 KNZ75385.1 - 0.16 12.0 1.7 0.23 11.5 1.7 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TPT PF03151.16 KNZ75386.1 - 4.7e-09 36.0 20.7 1.5e-08 34.4 20.7 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KNZ75386.1 - 0.00078 19.6 37.4 0.015 15.5 13.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family Carb_anhydrase PF00194.21 KNZ75388.1 - 2.3e-33 115.8 0.0 3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Chitin_synth_2 PF03142.15 KNZ75388.1 - 0.074 11.7 0.0 0.096 11.3 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase CA_like PF10563.9 KNZ75388.1 - 0.2 11.6 0.5 2.2 8.2 0.2 2.4 2 1 0 2 2 2 0 Putative carbonic anhydrase PAPS_reduct PF01507.19 KNZ75389.1 - 2.8e-31 108.9 0.0 3.4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SPOB_ab PF14682.6 KNZ75389.1 - 0.045 13.8 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Epimerase PF01370.21 KNZ75390.1 - 2.1e-51 174.7 0.0 2.9e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KNZ75390.1 - 1.2e-14 54.5 0.4 7.7e-14 51.8 0.4 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KNZ75390.1 - 1.5e-06 27.6 0.8 0.00037 19.7 0.9 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KNZ75390.1 - 0.00013 21.2 0.0 0.00037 19.7 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KNZ75390.1 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KNZ75390.1 - 0.053 12.7 0.2 0.95 8.6 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein GDP_Man_Dehyd PF16363.5 KNZ75391.1 - 1.4e-158 527.6 0.0 1.6e-158 527.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KNZ75391.1 - 1.4e-72 244.1 0.0 1.7e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KNZ75391.1 - 0.00054 19.2 0.0 0.00089 18.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KNZ75391.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SUZ PF12752.7 KNZ75392.1 - 3.3e-14 53.4 1.5 3.3e-14 53.4 1.5 2.5 2 1 0 2 2 2 1 SUZ domain SUZ-C PF12901.7 KNZ75392.1 - 0.048 13.7 0.3 0.15 12.1 0.3 1.9 1 0 0 1 1 1 0 SUZ-C motif Peptidase_M20 PF01546.28 KNZ75393.1 - 1.5e-33 116.2 0.0 2.2e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KNZ75393.1 - 1.1e-10 41.4 0.0 1.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KNZ75393.1 - 0.0037 17.0 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 MIP PF00230.20 KNZ75395.1 - 1.1e-53 182.3 10.6 1.2e-53 182.1 10.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4596 PF15363.6 KNZ75395.1 - 0.17 12.1 0.1 0.4 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) p450 PF00067.22 KNZ75397.1 - 1.1e-63 215.6 0.0 3.4e-63 214.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Mre11_DNA_bind PF04152.14 KNZ75398.1 - 4.9e-36 124.6 0.0 1.6e-35 122.9 0.0 1.9 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KNZ75398.1 - 1.9e-15 57.9 0.5 3e-15 57.3 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ75398.1 - 1.8e-05 25.0 0.0 0.00023 21.4 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Drf_GBD PF06371.13 KNZ75398.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain YL1 PF05764.13 KNZ75398.1 - 0.035 14.2 10.4 0.059 13.5 10.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein ZZ PF00569.17 KNZ75399.1 - 6.7e-05 22.6 4.1 0.00011 21.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type ABC_tran PF00005.27 KNZ75400.1 - 4.2e-23 82.4 0.0 8.5e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KNZ75400.1 - 3.9e-07 29.7 0.5 0.012 15.0 0.2 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KNZ75400.1 - 8.1e-07 29.1 0.0 4.3e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ75400.1 - 3.7e-06 26.9 0.0 1.9e-05 24.6 0.0 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KNZ75400.1 - 5.4e-05 23.5 0.0 0.0056 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ75400.1 - 0.00081 19.8 0.0 0.0044 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KNZ75400.1 - 0.002 17.8 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KNZ75400.1 - 0.0028 18.2 0.0 0.0059 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 KNZ75400.1 - 0.014 14.7 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain RsgA_GTPase PF03193.16 KNZ75400.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 KNZ75400.1 - 0.019 15.1 0.0 0.059 13.5 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase MTS_N PF08468.11 KNZ75400.1 - 0.029 14.4 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal AAA_30 PF13604.6 KNZ75400.1 - 0.04 13.6 0.0 0.13 11.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KNZ75400.1 - 0.042 13.0 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KNZ75400.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 KNZ75400.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RT_RNaseH PF17917.1 KNZ75401.1 - 8.1e-11 42.1 0.0 2.9e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ75401.1 - 6.4e-08 32.5 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Asp_protease_2 PF13650.6 KNZ75403.1 - 7.3e-05 23.3 0.0 0.00018 22.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ75403.1 - 0.00012 22.5 0.0 0.00023 21.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Aminotran_3 PF00202.21 KNZ75404.1 - 1.8e-38 132.3 0.0 1.2e-17 63.7 0.1 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 KNZ75404.1 - 9.1e-16 58.3 0.0 1.4e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain WD40 PF00400.32 KNZ75405.1 - 2.4e-14 53.5 6.9 4.6e-06 27.3 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75405.1 - 1.6e-10 41.1 1.3 0.00014 22.1 0.4 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ75405.1 - 0.00087 18.3 0.0 0.013 14.5 0.0 2.4 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ75405.1 - 0.0057 16.6 0.0 0.65 9.8 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A adh_short_C2 PF13561.6 KNZ75406.1 - 3.2e-50 170.9 0.0 3.6e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ75406.1 - 3.8e-30 104.8 0.0 4.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ75406.1 - 0.00014 21.9 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KNZ75407.1 - 6.3e-54 183.0 0.0 7.2e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ75407.1 - 2.6e-37 128.2 0.0 3.1e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ75407.1 - 1.5e-08 34.7 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain WD40 PF00400.32 KNZ75408.1 - 1.1e-15 57.7 12.3 8.4e-06 26.4 0.0 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75408.1 - 7.3e-05 23.0 0.1 0.48 10.8 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2358 PF10184.9 KNZ75408.1 - 0.0051 17.1 0.1 0.0096 16.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 KNZ75408.1 - 0.012 16.3 0.0 0.06 14.0 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Sulfate_transp PF00916.20 KNZ75409.1 - 5.4e-115 384.2 15.5 7.3e-115 383.7 15.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KNZ75409.1 - 1.1e-07 31.5 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KNZ75409.1 - 5.7e-05 23.5 11.5 0.0022 18.4 3.3 2.9 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 KNZ75409.1 - 0.014 15.7 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 STAS domain Transcrip_reg PF01709.20 KNZ75410.1 - 1e-58 198.6 0.1 1.2e-58 198.4 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator NYN PF01936.18 KNZ75411.1 - 3.7e-13 50.2 0.0 6.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 NYN domain Peptidase_C14 PF00656.22 KNZ75412.1 - 3.1e-11 43.7 0.0 3.9e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Chorismate_synt PF01264.21 KNZ75412.1 - 0.14 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Chorismate synthase Peptidase_C14 PF00656.22 KNZ75413.1 - 1.1e-22 81.3 0.0 1.9e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain NYN PF01936.18 KNZ75414.1 - 1.3e-43 149.0 0.1 2.5e-23 83.2 0.0 2.4 2 0 0 2 2 2 2 NYN domain CHCH PF06747.13 KNZ75415.1 - 0.00035 20.6 0.7 0.00045 20.3 0.7 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 KNZ75415.1 - 0.018 15.1 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Tweety PF04906.13 KNZ75415.1 - 0.035 12.8 0.1 0.041 12.5 0.1 1.0 1 0 0 1 1 1 0 Tweety Peptidase_C70 PF12385.8 KNZ75415.1 - 0.049 13.6 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 UQ_con PF00179.26 KNZ75416.1 - 1.2e-18 67.1 0.0 2.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.18 KNZ75416.1 - 0.36 10.2 0.1 0.36 10.2 0.1 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF2457 PF10446.9 KNZ75416.1 - 0.63 9.1 5.2 0.36 9.9 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) L31 PF09784.9 KNZ75417.1 - 4.4e-38 129.8 0.3 1.9e-34 118.2 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L31 CMS1 PF14617.6 KNZ75418.1 - 1e-81 274.0 3.6 1.3e-81 273.7 3.6 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit YL1 PF05764.13 KNZ75418.1 - 0.0022 18.1 5.6 0.0029 17.8 5.6 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Herpes_DNAp_acc PF04929.12 KNZ75418.1 - 2.5 7.0 8.4 1.6 7.6 6.7 1.5 1 1 1 2 2 2 0 Herpes DNA replication accessory factor RNase_T PF00929.24 KNZ75419.1 - 9.6e-14 52.3 0.0 1.6e-12 48.3 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Ndc80_HEC PF03801.13 KNZ75420.1 - 3.7e-34 117.5 0.0 8.2e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 KNZ75420.1 - 0.0015 18.6 2.8 0.0015 18.6 2.8 4.5 4 2 3 7 7 7 1 Domain of unknown function (DUF5595) Fib_alpha PF08702.10 KNZ75420.1 - 1 9.6 20.2 0.46 10.7 1.1 3.5 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KNZ75420.1 - 1.6 9.3 9.9 2.4 8.7 0.2 4.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 KNZ75420.1 - 2.5 8.1 24.3 0.19 11.7 1.2 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) CDT1_C PF16679.5 KNZ75420.1 - 2.9 8.4 7.3 0.82 10.1 3.3 2.1 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain Spc7 PF08317.11 KNZ75420.1 - 4.3 6.1 41.9 0.1 11.4 11.1 3.6 2 2 1 3 3 3 0 Spc7 kinetochore protein Lebercilin PF15619.6 KNZ75420.1 - 5.6 6.6 39.6 1.3 8.6 6.4 4.3 2 2 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Mog1 PF04603.12 KNZ75421.1 - 4e-37 127.6 0.0 5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF896 PF05979.12 KNZ75421.1 - 0.17 11.7 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF2383 PF09537.10 KNZ75422.1 - 2.7e-06 27.7 4.5 0.027 14.8 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2383) NRBF2_MIT PF17169.4 KNZ75422.1 - 0.0016 18.6 1.1 0.0016 18.6 1.1 2.6 2 0 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 bZIP_1 PF00170.21 KNZ75422.1 - 0.027 14.5 16.0 0.084 13.0 1.0 3.6 3 0 0 3 3 3 0 bZIP transcription factor Fib_alpha PF08702.10 KNZ75422.1 - 0.067 13.4 6.8 2.1 8.5 0.4 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family CCDC-167 PF15188.6 KNZ75422.1 - 0.16 12.3 11.3 0.72 10.2 0.1 3.4 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 TolA_bind_tri PF16331.5 KNZ75422.1 - 0.22 11.6 5.8 3.2 7.9 0.1 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation DUF4482 PF14818.6 KNZ75422.1 - 0.36 11.7 20.2 1.3 9.9 1.6 3.7 2 2 1 3 3 3 0 Domain of unknown function (DUF4482) TMCO5 PF14992.6 KNZ75422.1 - 0.62 9.6 10.6 1.2 8.7 0.1 3.0 3 0 0 3 3 3 0 TMCO5 family PHM7_cyt PF14703.6 KNZ75422.1 - 2.7 8.2 8.0 9.1 6.5 0.1 2.7 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CCDC92 PF14916.6 KNZ75422.1 - 2.8 7.8 7.6 5.2 6.9 0.2 3.1 3 1 1 4 4 4 0 Coiled-coil domain of unknown function Cnn_1N PF07989.11 KNZ75422.1 - 2.9 8.1 16.0 4.5 7.5 1.2 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 PspB PF06667.12 KNZ75422.1 - 3 8.0 4.8 1.2 9.2 0.5 2.6 2 0 0 2 2 2 0 Phage shock protein B HSBP1 PF06825.12 KNZ75422.1 - 3.3 7.6 5.1 1.8 8.5 0.1 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 zf-C4H2 PF10146.9 KNZ75422.1 - 3.5 7.9 11.5 14 5.9 2.0 3.1 3 0 0 3 3 3 0 Zinc finger-containing protein COQ7 PF03232.13 KNZ75422.1 - 5.3 6.8 7.7 8.7 6.1 0.6 2.4 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 Ax_dynein_light PF10211.9 KNZ75422.1 - 5.8 6.8 18.4 4.5 7.2 1.3 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain TSC22 PF01166.18 KNZ75422.1 - 6.6 7.1 8.5 21 5.5 0.1 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 KNZ75422.1 - 6.9 7.4 11.6 5.3 7.7 1.0 3.0 3 0 0 3 3 3 0 Initiation control protein YabA HECT PF00632.25 KNZ75423.1 - 5.4e-93 311.8 0.0 7.2e-93 311.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KNZ75423.1 - 6.8e-37 125.2 20.6 9.3e-13 48.0 6.3 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 KNZ75423.1 - 2.6e-20 72.6 0.2 6.8e-20 71.3 0.2 1.7 1 0 0 1 1 1 1 C2 domain Pox_MCEL PF03291.16 KNZ75424.1 - 3e-82 276.4 0.0 3.7e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 KNZ75424.1 - 5.9e-13 49.3 0.0 1.7e-07 31.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ75424.1 - 4.7e-08 33.6 0.1 8e-07 29.6 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ75424.1 - 4.7e-08 33.0 0.0 1.6e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ75424.1 - 8.1e-08 32.9 0.0 2.3e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ75424.1 - 9.2e-07 28.8 0.0 1.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ75424.1 - 0.019 14.5 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain TPMT PF05724.11 KNZ75424.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.17 KNZ75424.1 - 0.078 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 KNZ75424.1 - 0.21 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Rrn6 PF10214.9 KNZ75424.1 - 2.1 6.7 6.5 2.6 6.4 6.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ERAP1_C PF11838.8 KNZ75425.1 - 2.9e-76 257.0 0.2 5.6e-76 256.1 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KNZ75425.1 - 6.1e-69 231.9 0.3 9.2e-69 231.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KNZ75425.1 - 8.1e-44 150.0 0.4 1.5e-42 145.9 0.4 2.4 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF4913 PF16259.5 KNZ75425.1 - 0.00032 20.7 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4913) Bestrophin PF01062.21 KNZ75427.1 - 2e-40 139.0 0.0 1.6e-38 132.8 0.0 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel 2Fe-2S_thioredx PF01257.19 KNZ75428.1 - 1.7e-56 190.1 0.0 2.1e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Telomere_reg-2 PF10193.9 KNZ75429.1 - 6.2e-34 116.7 0.0 1.2e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 Telomere length regulation protein Peptidase_S41 PF03572.18 KNZ75430.1 - 5.8e-06 26.0 0.0 1.5e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Flavodoxin_1 PF00258.25 KNZ75430.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin Linker_histone PF00538.19 KNZ75431.1 - 1.7e-21 76.4 4.6 2.5e-21 75.8 0.0 2.5 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 KNZ75431.1 - 8.7 6.4 71.5 5.8 6.9 69.4 1.7 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 AMP-binding PF00501.28 KNZ75432.1 - 6.1e-19 67.9 0.0 1.2e-18 67.0 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.19 KNZ75433.1 - 1.7e-21 76.3 0.0 1.7e-21 76.3 0.0 2.4 2 1 0 2 2 2 1 linker histone H1 and H5 family RRM_1 PF00076.22 KNZ75435.1 - 3.6e-26 90.8 0.0 1.9e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 KNZ75435.1 - 1.4e-19 68.6 0.0 0.0001 21.8 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 KNZ75435.1 - 7e-05 22.6 0.0 0.041 13.8 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nab6_mRNP_bdg PF10567.9 KNZ75435.1 - 0.019 14.5 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA-recognition motif DUF4358 PF14270.6 KNZ75436.1 - 0.038 14.3 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Lipase_GDSL_lke PF16255.5 KNZ75436.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase RCC1 PF00415.18 KNZ75437.1 - 4.1e-19 68.9 11.1 8.5e-08 32.7 0.0 7.6 8 0 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNZ75437.1 - 1.3e-09 37.6 15.0 3.8e-06 26.5 0.0 6.2 7 0 0 7 7 7 2 Regulator of chromosome condensation (RCC1) repeat GBP_PSP PF02425.15 KNZ75437.1 - 0.093 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide NST1 PF13945.6 KNZ75438.1 - 3.7 7.6 7.0 7.5 6.6 7.0 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DPBB_1 PF03330.18 KNZ75439.1 - 0.0057 16.9 0.0 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 Lytic transglycolase SOG2 PF10428.9 KNZ75439.1 - 8 5.5 22.6 10 5.2 22.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DPBB_1 PF03330.18 KNZ75440.1 - 0.0037 17.5 0.0 0.0078 16.5 0.0 1.7 1 1 0 1 1 1 1 Lytic transglycolase SOG2 PF10428.9 KNZ75440.1 - 0.02 14.1 11.2 0.023 13.9 11.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Endomucin PF07010.12 KNZ75440.1 - 0.9 9.5 25.1 1.2 9.0 25.1 1.1 1 0 0 1 1 1 0 Endomucin DPBB_1 PF03330.18 KNZ75441.1 - 0.011 15.9 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 Lytic transglycolase Apt1 PF10351.9 KNZ75441.1 - 0.79 8.5 5.4 1 8.1 5.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 KNZ75441.1 - 2.7 7.1 19.0 3.8 6.6 19.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein E1-E2_ATPase PF00122.20 KNZ75442.1 - 1e-51 175.1 2.3 1e-51 175.1 2.3 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNZ75442.1 - 4.9e-45 153.5 8.2 4.9e-45 153.5 8.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 KNZ75442.1 - 5.4e-21 74.1 0.1 5.2e-19 67.7 0.0 3.0 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KNZ75442.1 - 6.8e-20 71.0 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KNZ75442.1 - 1.5e-17 64.6 3.8 4.2e-17 63.1 1.5 2.9 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KNZ75442.1 - 1.3e-06 28.4 2.1 1.3e-05 25.1 1.8 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KNZ75442.1 - 0.00023 21.7 0.0 0.00063 20.2 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 KNZ75443.1 - 0.0028 17.5 8.2 0.0055 16.5 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FliO PF04347.13 KNZ75443.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 1 0 1 1 1 0 Flagellar biosynthesis protein, FliO Zn-C2H2_12 PF18112.1 KNZ75443.1 - 0.14 12.7 0.6 0.36 11.3 0.6 1.7 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Nuc_sug_transp PF04142.15 KNZ75445.1 - 6.8e-08 32.0 1.4 9.8e-08 31.5 1.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KNZ75445.1 - 1.6e-05 24.4 1.6 1.6e-05 24.4 1.6 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.20 KNZ75445.1 - 0.00033 20.8 7.6 0.00033 20.8 7.6 2.7 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 KNZ75445.1 - 0.0024 17.2 0.2 0.0024 17.2 0.2 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SMP_LBD PF17047.5 KNZ75445.1 - 0.078 12.4 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain SHQ1 PF04925.15 KNZ75446.1 - 1.5e-56 190.7 0.1 2.1e-56 190.2 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 KNZ75446.1 - 3.7e-06 27.3 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 PIH1 CS-like domain CS PF04969.16 KNZ75446.1 - 0.062 14.3 0.0 0.18 12.8 0.0 1.9 1 0 0 1 1 1 0 CS domain SIL1 PF16782.5 KNZ75446.1 - 1.2 8.3 4.3 13 4.8 0.3 2.2 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 Iwr1 PF08574.10 KNZ75446.1 - 1.3 10.1 12.0 9.7 7.3 0.3 2.8 2 1 0 2 2 2 0 Transcription factor Iwr1 Chorismate_bind PF00425.18 KNZ75447.1 - 4.5e-91 305.0 0.0 7.6e-91 304.2 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KNZ75447.1 - 9.7e-30 103.6 0.0 1.7e-28 99.6 0.0 2.8 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Ribosomal_S2 PF00318.20 KNZ75448.1 - 2.7e-50 170.6 0.0 1.8e-25 89.5 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Phosphatase PF15698.5 KNZ75448.1 - 0.023 13.8 0.1 0.061 12.5 0.0 1.6 1 1 0 2 2 2 0 Phosphatase HSP70 PF00012.20 KNZ75449.1 - 2.2e-237 789.1 6.5 2.4e-237 788.9 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNZ75449.1 - 5.5e-17 61.6 0.7 5.4e-16 58.3 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KNZ75449.1 - 0.0062 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 KNZ75449.1 - 0.0094 15.0 0.5 0.089 11.8 0.2 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 KNZ75449.1 - 0.015 14.8 0.2 3.1 7.2 0.1 2.6 2 1 1 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Zincin_2 PF10103.9 KNZ75449.1 - 0.024 13.9 0.1 0.048 12.9 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Hydantoinase_A PF01968.18 KNZ75449.1 - 0.031 13.5 0.2 0.069 12.4 0.2 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KNZ75449.1 - 0.055 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 StbA protein AAA PF00004.29 KNZ75450.1 - 3.6e-14 53.3 0.0 9.8e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 KNZ75450.1 - 7.8e-13 48.7 0.0 2.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KNZ75450.1 - 6.2e-12 45.6 0.0 2.4e-10 40.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KNZ75450.1 - 2e-08 34.3 0.0 4e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KNZ75450.1 - 1.7e-05 25.1 0.0 0.00027 21.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KNZ75450.1 - 4.4e-05 23.4 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KNZ75450.1 - 4.7e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 KNZ75450.1 - 0.00012 22.5 0.1 0.00051 20.5 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KNZ75450.1 - 0.00041 20.1 0.0 0.0021 17.8 0.0 2.1 2 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KNZ75450.1 - 0.00046 20.0 0.0 0.0011 18.7 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNZ75450.1 - 0.00061 19.8 0.0 0.0021 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KNZ75450.1 - 0.00065 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KNZ75450.1 - 0.0012 18.2 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KNZ75450.1 - 0.0023 17.5 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 KNZ75450.1 - 0.0029 17.9 0.0 0.012 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ75450.1 - 0.005 16.9 0.0 0.042 13.8 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KNZ75450.1 - 0.038 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 KNZ75450.1 - 0.042 13.6 0.1 0.45 10.3 0.0 2.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 KNZ75450.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KNZ75450.1 - 0.077 13.5 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KNZ75450.1 - 0.078 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DUF815 PF05673.13 KNZ75450.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 KNZ75450.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.14 KNZ75450.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sec3_C_2 PF15278.6 KNZ75450.1 - 0.16 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit CAF1A PF12253.8 KNZ75451.1 - 4.4e-18 65.2 0.1 4.4e-18 65.2 0.1 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A Spc24 PF08286.11 KNZ75452.1 - 6.8e-20 71.3 1.1 1.6e-19 70.1 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4061 PF13270.6 KNZ75452.1 - 0.064 13.6 2.2 3.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Med9 PF07544.13 KNZ75452.1 - 0.1 12.7 4.4 1.7 8.8 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ZnuA PF01297.17 KNZ75452.1 - 0.19 11.1 1.4 0.28 10.6 0.1 1.7 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic V_ATPase_I PF01496.19 KNZ75452.1 - 0.33 8.8 2.6 0.39 8.6 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KNZ75452.1 - 0.34 11.3 2.3 3.1 8.3 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4349 PF14257.6 KNZ75452.1 - 0.63 9.5 6.1 0.56 9.6 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) GPS2_interact PF15784.5 KNZ75452.1 - 0.74 10.3 6.0 0.19 12.2 2.4 1.8 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain APG6_N PF17675.1 KNZ75452.1 - 0.79 10.2 10.0 1.2 9.7 10.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region BST2 PF16716.5 KNZ75452.1 - 1.4 9.5 7.1 2.1 9.0 0.7 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DivIC PF04977.15 KNZ75452.1 - 2 8.2 6.1 2.6 7.9 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator T2SSM PF04612.12 KNZ75452.1 - 2 8.4 7.5 8.6 6.4 0.2 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M OmpH PF03938.14 KNZ75452.1 - 4.4 7.6 9.6 23 5.3 9.6 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ADH_zinc_N_2 PF13602.6 KNZ75453.1 - 1.3e-18 68.3 0.0 2.5e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KNZ75453.1 - 2.5e-13 50.2 0.0 1.8e-12 47.4 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Prot_ATP_OB_N PF17758.1 KNZ75453.1 - 0.013 15.1 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain ADH_N PF08240.12 KNZ75453.1 - 0.046 13.6 0.0 0.33 10.9 0.0 2.2 2 1 1 3 3 3 0 Alcohol dehydrogenase GroES-like domain ProQ_C PF17516.2 KNZ75453.1 - 0.056 12.9 0.3 0.11 11.9 0.3 1.5 1 0 0 1 1 1 0 ProQ C-terminal domain ADH_N_2 PF16884.5 KNZ75453.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase CRM1_C PF08767.11 KNZ75454.1 - 3.6e-133 443.7 1.8 3.6e-133 443.7 1.8 3.4 3 1 1 4 4 4 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 KNZ75454.1 - 1.3e-33 114.5 4.3 3.5e-33 113.1 4.3 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 KNZ75454.1 - 1.6e-32 112.6 9.2 2.3e-32 112.1 4.9 3.6 6 0 0 6 6 6 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 KNZ75454.1 - 1.6e-30 104.9 1.4 1.6e-30 104.9 1.4 3.3 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KNZ75454.1 - 1.6e-18 65.9 2.4 1.6e-18 65.9 2.4 2.4 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KNZ75454.1 - 6.9e-13 48.3 0.0 2.2e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 KNZ75454.1 - 0.014 15.4 0.9 0.43 10.5 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) UCH PF00443.29 KNZ75454.1 - 0.23 10.9 0.3 0.76 9.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Vac14_Fab1_bd PF12755.7 KNZ75454.1 - 0.45 11.1 2.5 5.1 7.8 0.1 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Pre-PUA PF17832.1 KNZ75455.1 - 5.1e-24 84.8 0.0 7e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KNZ75455.1 - 1.7e-12 47.1 0.1 3e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KNZ75455.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) SRR1 PF07985.12 KNZ75456.1 - 2.7e-09 36.9 0.7 5.9e-09 35.8 0.1 1.8 2 0 0 2 2 2 1 SRR1 DUF2508 PF10704.9 KNZ75456.1 - 0.13 12.4 0.4 0.25 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) TPR_1 PF00515.28 KNZ75458.1 - 1.5e-25 87.9 3.8 1.5e-07 31.0 0.1 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ75458.1 - 3.9e-23 79.7 13.1 0.00026 20.9 0.2 9.8 10 0 0 10 10 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ75458.1 - 8.3e-18 64.4 16.3 5.7e-14 52.1 1.9 5.8 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KNZ75458.1 - 7.8e-16 58.4 9.9 0.0033 17.9 0.0 7.7 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75458.1 - 5e-15 54.9 15.1 0.0095 16.7 0.2 9.0 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ75458.1 - 5.5e-15 54.3 3.9 0.24 11.7 0.1 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ75458.1 - 8e-15 55.2 13.6 4.3e-05 24.1 0.1 7.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ75458.1 - 1e-12 47.5 1.6 0.87 10.1 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ75458.1 - 2.3e-12 46.4 0.4 1.1 9.0 0.0 6.1 6 0 0 6 6 6 4 TPR repeat TPR_12 PF13424.6 KNZ75458.1 - 2.8e-10 40.4 19.4 0.00062 20.0 1.1 8.4 5 1 4 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ75458.1 - 2.7e-08 33.9 4.9 2.4 9.0 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ75458.1 - 4.2e-05 22.9 8.2 0.029 13.6 1.5 3.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ75458.1 - 4.7e-05 23.1 6.3 1.7 8.8 0.0 7.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ75458.1 - 0.00022 21.3 9.9 0.0064 16.6 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ75458.1 - 0.89 10.4 5.8 12 6.9 0.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 KNZ75459.1 - 5.5e-149 496.9 13.5 6.2e-149 496.8 13.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 KNZ75459.1 - 0.00018 21.1 0.2 0.00045 19.8 0.0 1.7 2 0 0 2 2 2 1 Telomere recombination Rhodanese PF00581.20 KNZ75460.1 - 1.4e-13 51.3 0.0 3.7e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Lipase_GDSL_2 PF13472.6 KNZ75461.1 - 3.1e-28 99.4 0.0 3.3e-27 96.0 0.0 2.1 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KNZ75461.1 - 3e-20 73.1 0.0 4.2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DsrH PF04077.12 KNZ75461.1 - 0.016 15.3 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 DsrH like protein tRNA_int_endo PF01974.17 KNZ75462.1 - 1.6e-13 50.5 0.0 4.7e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain EI24 PF07264.11 KNZ75463.1 - 1.8e-32 113.0 7.5 2.3e-32 112.7 7.5 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Linker_histone PF00538.19 KNZ75464.1 - 2.8e-21 75.7 0.4 8.7e-21 74.1 0.0 2.1 2 1 1 3 3 3 1 linker histone H1 and H5 family SOG2 PF10428.9 KNZ75464.1 - 1.5 8.0 16.0 1.7 7.7 16.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RF-1 PF00472.20 KNZ75465.1 - 1.2e-23 83.2 2.4 4e-23 81.6 2.4 1.9 1 0 0 1 1 1 1 RF-1 domain TFIIA PF03153.13 KNZ75465.1 - 0.05 13.6 8.1 0.064 13.2 8.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP_N PF01213.19 KNZ75466.1 - 7.1e-84 282.0 36.8 2.4e-82 277.0 36.8 3.0 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KNZ75466.1 - 2e-59 199.7 3.3 2.7e-59 199.3 3.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 KNZ75466.1 - 0.0043 16.8 2.9 0.0099 15.6 3.0 1.7 1 1 0 1 1 1 1 Tubulin binding cofactor C Mito_fiss_reg PF05308.11 KNZ75466.1 - 3.7 7.5 25.7 0.23 11.5 7.9 2.7 2 1 1 3 3 3 0 Mitochondrial fission regulator SPRY PF00622.28 KNZ75468.1 - 5.3e-09 36.2 0.0 8.8e-07 29.1 0.0 3.1 3 0 0 3 3 3 1 SPRY domain CMS1 PF14617.6 KNZ75468.1 - 3.9 6.7 5.2 7.7 5.8 3.2 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit UQ_con PF00179.26 KNZ75469.1 - 2.3e-29 101.9 0.0 2.6e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nt_Gln_amidase PF09764.9 KNZ75473.1 - 1.3e-30 106.4 0.1 1.5e-30 106.2 0.1 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase ATP12 PF07542.11 KNZ75475.1 - 1.3e-24 86.7 1.1 2.1e-24 86.0 1.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein DUF3535 PF12054.8 KNZ75475.1 - 0.058 12.6 1.6 0.067 12.4 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) MutS_V PF00488.21 KNZ75476.1 - 2.5e-67 226.5 1.0 5.9e-67 225.4 0.3 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KNZ75476.1 - 8.5e-36 124.0 0.8 2.8e-35 122.3 0.8 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KNZ75476.1 - 8.1e-23 80.8 0.0 1.8e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KNZ75476.1 - 2.3e-11 44.1 0.1 2.9e-10 40.5 0.0 2.7 3 0 0 3 3 3 1 MutS domain II DNA_pol_phi PF04931.13 KNZ75477.1 - 1.7e-228 760.6 5.4 1.7e-228 760.6 5.4 1.9 2 0 0 2 2 2 1 DNA polymerase phi Glycos_transf_1 PF00534.20 KNZ75478.1 - 5.8e-20 71.5 0.0 1.2e-19 70.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KNZ75478.1 - 9.1e-14 52.0 0.0 1.6e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KNZ75478.1 - 1.6e-06 28.4 0.0 3.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-RRN7 PF11781.8 KNZ75479.1 - 0.00012 21.6 1.4 0.00021 20.9 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 KNZ75479.1 - 0.00028 20.3 0.4 0.00056 19.4 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIB PF00382.19 KNZ75479.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Abhydrolase_1 PF00561.20 KNZ75480.1 - 1.9e-15 57.2 0.0 2.3e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75480.1 - 4.5e-09 37.2 0.0 7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ75480.1 - 7.2e-07 28.7 0.1 9.7e-07 28.3 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KNZ75480.1 - 3.9e-05 23.9 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KNZ75480.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein ZapB PF06005.12 KNZ75481.1 - 0.0033 17.8 4.7 0.0033 17.8 4.7 6.1 2 1 4 6 6 6 2 Cell division protein ZapB Glyco_trans_A_1 PF09318.10 KNZ75481.1 - 0.75 9.5 7.8 0.88 9.2 0.3 2.3 2 0 0 2 2 2 0 Glycosyl transferase 1 domain A Fez1 PF06818.15 KNZ75481.1 - 2.7 8.4 40.6 14 6.0 16.5 2.8 1 1 1 2 2 2 0 Fez1 Sugarporin_N PF11471.8 KNZ75481.1 - 9.5 6.3 11.8 0.17 11.9 0.9 3.1 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension NAC PF01849.18 KNZ75482.1 - 9.4e-21 73.6 0.0 1.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 KNZ75482.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain PBP1_TM PF14812.6 KNZ75482.1 - 1.6 9.2 4.7 1.2 9.6 0.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_11 PF08241.12 KNZ75483.1 - 1.3e-07 32.2 0.0 2.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ75483.1 - 1.5e-05 25.6 0.0 3.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ75483.1 - 4.6e-05 23.2 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ75483.1 - 0.00069 19.5 0.0 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ75483.1 - 0.0078 16.9 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Glyco_tran_28_C PF04101.16 KNZ75484.1 - 3.7e-29 101.9 0.0 4.3e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain P5CR_dimer PF14748.6 KNZ75485.1 - 4.6e-39 132.8 2.8 8.7e-39 131.9 2.8 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KNZ75485.1 - 8.2e-09 35.9 0.0 1.7e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AAA PF00004.29 KNZ75486.1 - 3.1e-44 150.6 0.0 6e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KNZ75486.1 - 1.3e-10 41.1 0.1 8.8e-10 38.4 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KNZ75486.1 - 2.7e-08 33.9 0.1 8.9e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ75486.1 - 6.6e-08 33.1 0.5 3.3e-05 24.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 KNZ75486.1 - 2e-07 31.3 0.0 4.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KNZ75486.1 - 3.5e-06 26.4 0.0 6.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KNZ75486.1 - 0.00011 22.5 0.9 0.016 15.5 0.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_lid_3 PF17862.1 KNZ75486.1 - 0.0004 20.1 0.0 0.00095 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 KNZ75486.1 - 0.00051 20.1 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KNZ75486.1 - 0.00064 19.5 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KNZ75486.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KNZ75486.1 - 0.0011 19.5 0.0 0.0027 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 KNZ75486.1 - 0.0014 18.6 0.0 0.017 15.2 0.0 2.1 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KNZ75486.1 - 0.0017 18.3 0.0 0.0094 15.9 0.0 2.1 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 KNZ75486.1 - 0.0024 18.2 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 KNZ75486.1 - 0.0042 16.8 0.3 0.011 15.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KNZ75486.1 - 0.0046 16.5 0.1 0.028 13.9 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KNZ75486.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KNZ75486.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 KNZ75486.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 KNZ75486.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KNZ75486.1 - 0.014 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KNZ75486.1 - 0.015 15.2 0.1 0.093 12.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 KNZ75486.1 - 0.018 14.7 0.4 0.059 12.9 0.1 1.8 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 KNZ75486.1 - 0.033 13.6 0.0 0.7 9.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KNZ75486.1 - 0.034 13.9 0.1 0.068 12.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KNZ75486.1 - 0.054 13.3 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KNZ75486.1 - 0.064 13.6 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KNZ75486.1 - 0.081 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase ATPase_2 PF01637.18 KNZ75486.1 - 0.09 12.7 0.1 0.82 9.5 0.0 2.4 2 1 1 3 3 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KNZ75486.1 - 0.11 11.8 0.0 0.59 9.4 0.0 2.0 2 0 0 2 2 2 0 KaiC Bac_DnaA PF00308.18 KNZ75486.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KNZ75486.1 - 0.14 11.9 0.3 1.4 8.6 0.0 2.5 3 1 0 3 3 3 0 Sigma-54 interaction domain DUF2567 PF10821.8 KNZ75486.1 - 0.14 12.2 0.1 0.42 10.7 0.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2567) Parvo_NS1 PF01057.17 KNZ75486.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.22 KNZ75487.1 - 8.5e-12 44.7 0.0 2.2e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNRNP27 PF08648.12 KNZ75489.1 - 1.9e-28 98.3 0.5 3.4e-28 97.5 0.5 1.4 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins SUI1 PF01253.22 KNZ75490.1 - 2.4e-27 95.3 0.7 3.2e-27 94.9 0.7 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 rRNA_processing PF08524.11 KNZ75491.1 - 0.0074 16.3 0.8 0.0074 16.3 0.8 2.7 2 1 0 2 2 2 1 rRNA processing PPP4R2 PF09184.11 KNZ75492.1 - 1.4e-21 77.4 0.9 1.4e-21 77.3 0.9 1.4 1 1 0 1 1 1 1 PPP4R2 PAP2 PF01569.21 KNZ75493.1 - 7.2e-31 106.8 0.8 1.3e-30 106.0 0.8 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 KNZ75493.1 - 0.069 13.1 0.1 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Cullin_binding PF03556.15 KNZ75494.1 - 6.6e-25 87.9 2.4 1e-24 87.3 2.4 1.3 1 0 0 1 1 1 1 Cullin binding N-SET PF11764.8 KNZ75494.1 - 0.16 12.0 0.4 0.36 10.9 0.1 1.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N FeS_assembly_P PF01883.19 KNZ75495.1 - 4.1e-15 55.7 0.0 7.8e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PsaN PF05479.11 KNZ75495.1 - 0.19 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) MRG PF05712.13 KNZ75497.1 - 3.4e-51 173.4 0.0 4.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KNZ75497.1 - 2e-07 30.8 0.0 3.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.25 KNZ75498.1 - 3.7e-22 79.0 0.0 4.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75498.1 - 2.6e-09 36.8 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ75498.1 - 4.6e-07 29.0 0.5 5.9e-07 28.6 0.5 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ75498.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 KNZ75499.1 - 4.6e-16 58.9 0.0 4e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ75499.1 - 8.6e-11 41.6 0.0 1.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KNZ75499.1 - 1.7e-09 37.8 0.2 1.8e-06 28.1 0.0 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KNZ75499.1 - 4.7e-09 35.2 0.0 2.1e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KNZ75499.1 - 1.2e-08 34.6 0.1 0.0013 18.0 0.5 3.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ75499.1 - 2.6e-07 30.6 2.5 0.061 12.9 0.5 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KNZ75499.1 - 3.7e-06 27.4 0.4 0.0009 19.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KNZ75499.1 - 1.5e-05 24.5 0.0 0.067 12.5 0.0 3.2 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KNZ75499.1 - 2.1e-05 24.6 0.1 0.096 12.7 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KNZ75499.1 - 0.0003 20.1 1.1 0.0067 15.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 KNZ75499.1 - 0.00031 20.0 1.9 2.5 7.1 0.2 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A ApbA PF02558.16 KNZ75499.1 - 0.00059 19.5 2.5 0.026 14.2 0.5 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 KNZ75499.1 - 0.00062 20.2 0.0 0.097 13.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KNZ75499.1 - 0.0013 18.0 1.2 0.0023 17.2 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 KNZ75499.1 - 0.008 16.2 0.0 0.62 10.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KNZ75499.1 - 0.009 14.8 5.8 0.033 12.9 0.2 3.5 4 0 0 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 KNZ75499.1 - 0.011 15.7 1.7 0.41 10.5 0.2 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KNZ75499.1 - 0.02 13.9 0.1 2.4 7.1 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KNZ75499.1 - 0.062 12.7 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KNZ75499.1 - 0.08 13.5 0.6 20 5.8 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 KNZ75499.1 - 0.13 11.3 3.2 0.4 9.7 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KNZ75499.1 - 0.36 9.6 2.5 25 3.5 0.1 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Glyco_hydro_10 PF00331.20 KNZ75500.1 - 2.6e-96 322.5 0.4 3.8e-96 321.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KNZ75500.1 - 1.9e-13 50.1 9.4 5.7e-13 48.6 9.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain PRELI PF04707.14 KNZ75500.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 1 0 1 1 1 0 PRELI-like family Glyco_hydro_10 PF00331.20 KNZ75501.1 - 1.1e-101 340.2 0.0 1.3e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 PRELI PF04707.14 KNZ75501.1 - 0.04 13.7 0.0 0.16 11.8 0.0 1.8 1 1 1 2 2 2 0 PRELI-like family ALG3 PF05208.13 KNZ75502.1 - 1.6e-137 458.7 13.5 2.2e-137 458.3 13.5 1.1 1 0 0 1 1 1 1 ALG3 protein Cellulase PF00150.18 KNZ75502.1 - 6.1e-13 48.8 0.0 9.3e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TBP PF00352.21 KNZ75503.1 - 4e-61 202.9 0.1 2.7e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KNZ75503.1 - 0.00019 21.5 0.0 0.35 11.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 KNZ75503.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Dynamin_M PF01031.20 KNZ75504.1 - 2.9e-99 331.9 0.0 6.5e-99 330.7 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KNZ75504.1 - 2e-55 187.4 0.0 3.5e-55 186.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KNZ75504.1 - 2.8e-25 88.3 1.9 8.8e-25 86.7 1.9 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KNZ75504.1 - 0.00017 21.7 0.1 0.0021 18.1 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase BCS1_N PF08740.11 KNZ75505.1 - 7.2e-43 146.7 2.5 7.2e-43 146.7 2.5 2.7 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.29 KNZ75505.1 - 2.6e-16 60.2 0.0 8.2e-16 58.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TFIIA PF03153.13 KNZ75505.1 - 0.00041 20.5 17.5 0.00064 19.8 17.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AAA_29 PF13555.6 KNZ75505.1 - 0.00047 19.9 0.2 0.016 14.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 KNZ75505.1 - 0.0015 19.0 0.0 0.0015 19.0 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ75505.1 - 0.0037 17.0 0.9 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 KNZ75505.1 - 0.079 13.1 0.0 0.079 13.1 0.0 2.9 2 2 0 3 3 3 0 AAA domain ABC_tran PF00005.27 KNZ75505.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.6 2 1 0 2 2 1 0 ABC transporter MMR_HSR1 PF01926.23 KNZ75505.1 - 1 9.5 0.0 1 9.5 0.0 2.7 2 1 0 2 2 1 0 50S ribosome-binding GTPase TFIIF_alpha PF05793.12 KNZ75505.1 - 5.8 5.4 45.7 9.8 4.6 45.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AAA_11 PF13086.6 KNZ75505.1 - 8.7 6.0 0.0 8.7 6.0 0.0 3.3 2 1 1 3 3 2 0 AAA domain Glyco_hydro_88 PF07470.13 KNZ75506.1 - 3.3e-08 33.0 0.2 2.5e-07 30.1 0.2 2.2 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pkinase PF00069.25 KNZ75507.1 - 5.6e-49 166.9 0.0 8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75507.1 - 9.5e-17 61.1 0.0 4.2e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ75507.1 - 2.2e-06 27.8 0.0 0.0042 17.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ75507.1 - 2.8e-06 26.9 0.0 6.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ75507.1 - 0.015 14.1 0.0 0.015 14.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase SMI1_KNR4 PF09346.10 KNZ75508.1 - 4.4e-23 82.1 0.0 1.7e-22 80.2 0.0 1.9 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) BTK PF00779.19 KNZ75508.1 - 0.16 11.8 0.4 0.39 10.6 0.4 1.6 1 0 0 1 1 1 0 BTK motif p450 PF00067.22 KNZ75509.1 - 1.1e-22 80.5 0.0 1.2e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 KNZ75509.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.3 1 1 0 1 1 1 0 Putative cyclase Ferric_reduct PF01794.19 KNZ75510.1 - 3.9e-15 56.1 16.6 7.3e-15 55.2 13.0 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KNZ75510.1 - 1.4e-10 41.5 0.0 2.7e-08 34.1 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KNZ75510.1 - 0.00034 20.7 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Aldedh PF00171.22 KNZ75511.1 - 8.7e-126 420.1 0.0 1e-125 419.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3149 PF11346.8 KNZ75511.1 - 0.087 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) HSP90 PF00183.18 KNZ75512.1 - 9.8e-230 763.8 26.2 1.2e-229 763.5 26.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KNZ75512.1 - 4.1e-14 53.0 0.0 8.4e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KNZ75512.1 - 2.4e-09 37.2 0.1 7.8e-09 35.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 KNZ75512.1 - 2.6 8.1 13.7 1.5 8.9 10.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Aminotran_5 PF00266.19 KNZ75513.1 - 1.1e-34 120.1 0.0 1.7e-34 119.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V NHase_beta PF02211.15 KNZ75513.1 - 0.067 13.2 0.2 2.5 8.1 0.1 2.1 2 0 0 2 2 2 0 Nitrile hydratase beta subunit TRAPPC10 PF12584.8 KNZ75514.1 - 4.9e-35 120.5 0.0 1e-34 119.5 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 KNZ75514.1 - 0.01 15.9 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DEAD PF00270.29 KNZ75515.1 - 2.2e-48 164.3 0.0 3.6e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ75515.1 - 2.6e-26 92.1 0.0 1e-25 90.2 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ75515.1 - 2.2e-05 24.5 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNZ75515.1 - 0.12 12.7 0.0 0.34 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Linker_histone PF00538.19 KNZ75516.1 - 7.9e-08 32.6 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family 2OG-FeII_Oxy_3 PF13640.6 KNZ75516.1 - 0.00028 21.7 0.0 0.00055 20.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NTF2 PF02136.20 KNZ75517.1 - 2.7e-15 57.0 0.0 3.6e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Glyco_hydro_88 PF07470.13 KNZ75519.1 - 1.4e-13 50.6 0.0 1.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KNZ75519.1 - 0.0016 18.0 2.1 0.0037 16.8 2.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 KNZ75519.1 - 0.015 14.6 0.0 0.72 9.0 0.0 2.2 2 0 0 2 2 2 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_127 PF07944.12 KNZ75519.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.4 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Pkinase PF00069.25 KNZ75520.1 - 2e-44 152.0 0.0 2.6e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75520.1 - 9.7e-13 48.0 0.0 1.6e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ75520.1 - 1.6e-05 25.0 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ75520.1 - 0.00028 20.3 0.0 0.00073 18.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ75520.1 - 0.0014 17.5 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_fungal PF17667.1 KNZ75521.1 - 7.2e-42 143.6 15.5 1.3e-24 86.7 0.1 2.8 3 0 0 3 3 3 2 Fungal protein kinase Pkinase PF00069.25 KNZ75521.1 - 8.4e-05 22.1 0.2 0.00015 21.3 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ75521.1 - 0.00022 21.3 0.3 0.075 12.9 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ75521.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KNZ75521.1 - 0.15 11.3 0.1 0.26 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF554 PF04474.12 KNZ75523.1 - 0.2 11.1 0.0 0.41 10.1 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF554) Zn_clus PF00172.18 KNZ75523.1 - 1.7 8.8 8.9 4.7 7.4 0.8 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 KNZ75524.1 - 7.1e-24 84.5 0.0 1.3e-16 60.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ75524.1 - 5.7e-13 49.2 0.5 2.9e-12 46.9 0.1 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ75524.1 - 0.00055 20.0 0.0 0.002 18.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BORG_CEP PF14957.6 KNZ75524.1 - 0.058 14.6 1.0 0.19 12.9 0.2 2.1 2 0 0 2 2 2 0 Cdc42 effector DSPc PF00782.20 KNZ75525.1 - 3.2e-29 101.4 0.0 4.4e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KNZ75525.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 KNZ75525.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KNZ75525.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KNZ75525.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_hydro_31 PF01055.26 KNZ75526.1 - 8e-114 381.2 0.8 1e-113 380.9 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KNZ75526.1 - 1.6e-17 63.6 0.1 7.4e-17 61.4 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Amidohydro_3 PF07969.11 KNZ75527.1 - 3.2e-83 280.8 0.0 3.8e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KNZ75527.1 - 1.5e-13 50.8 0.2 1.1e-07 31.5 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family CTP_transf_like PF01467.26 KNZ75528.1 - 1.4e-24 86.9 0.0 2.8e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2786 PF10979.8 KNZ75529.1 - 1.2e-08 34.7 0.4 1.2e-08 34.7 0.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) PET117 PF15786.5 KNZ75529.1 - 0.24 11.7 3.6 0.57 10.5 3.6 1.6 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial DUF357 PF04010.13 KNZ75529.1 - 5.2 7.2 5.7 31 4.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF357) Abhydrolase_2 PF02230.16 KNZ75530.1 - 4.4e-11 43.0 0.0 2.4e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KNZ75530.1 - 0.038 14.6 0.6 0.046 14.3 0.6 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4502 PF14950.6 KNZ75531.1 - 0.13 11.6 0.7 0.41 10.0 0.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4502) TFA2_Winged_2 PF18121.1 KNZ75532.1 - 1.4e-20 72.8 0.3 3.5e-20 71.4 0.1 1.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KNZ75532.1 - 7.8e-16 58.1 0.7 2.9e-15 56.3 0.3 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain Yae1_N PF09811.9 KNZ75533.1 - 2.2e-09 36.8 2.0 4.6e-08 32.6 0.7 2.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Methyltransf_32 PF13679.6 KNZ75533.1 - 0.07 13.1 0.1 0.097 12.7 0.1 1.1 1 0 0 1 1 1 0 Methyltransferase domain Vir_act_alpha_C PF10400.9 KNZ75533.1 - 0.075 13.7 0.4 0.14 12.9 0.4 1.4 1 0 0 1 1 1 0 Virulence activator alpha C-term DUF3292 PF11696.8 KNZ75533.1 - 0.11 10.8 0.4 0.14 10.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Alpha_Helical PF18489.1 KNZ75533.1 - 0.14 12.4 0.1 0.35 11.0 0.1 1.8 1 1 0 1 1 1 0 Alpha helical domain TipAS PF07739.13 KNZ75533.1 - 1.2 9.7 6.0 0.61 10.6 1.5 2.5 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Abhydrolase_1 PF00561.20 KNZ75534.1 - 3.2e-18 66.3 0.1 9.5e-18 64.8 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75534.1 - 1.4e-14 55.2 0.0 1.7e-14 55.0 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ75534.1 - 2.1e-05 23.9 0.0 3.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KNZ75534.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Ndr family Peptidase_S74 PF13884.6 KNZ75534.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Chaperone of endosialidase Abhydrolase_1 PF00561.20 KNZ75535.1 - 1.1e-16 61.2 0.1 6.6e-16 58.7 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75535.1 - 3.1e-13 50.8 0.0 4.3e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ75535.1 - 4.7e-05 22.8 0.0 8.5e-05 21.9 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KNZ75535.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Peptidase_S74 PF13884.6 KNZ75535.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Gp_dh_C PF02800.20 KNZ75536.1 - 2.4e-69 231.9 0.0 3.3e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KNZ75536.1 - 1.4e-34 118.4 0.0 3.8e-34 117.0 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ipi1_N PF12333.8 KNZ75536.1 - 0.034 14.7 0.0 0.082 13.5 0.0 1.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF1664 PF07889.12 KNZ75537.1 - 3.1 7.9 39.5 0.68 10.0 4.7 5.3 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) ERM PF00769.19 KNZ75537.1 - 9.4 6.0 93.6 0.045 13.6 28.4 3.9 2 1 2 4 4 4 0 Ezrin/radixin/moesin family AA_permease_2 PF13520.6 KNZ75538.1 - 2.1e-57 194.9 36.4 3.3e-57 194.2 36.3 1.3 1 1 0 1 1 1 1 Amino acid permease Phage_holin_5_1 PF06946.11 KNZ75538.1 - 0.18 12.2 1.7 0.44 11.0 0.2 2.4 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 DUF2587 PF10759.9 KNZ75538.1 - 0.2 11.2 0.2 0.48 9.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) GPI2 PF06432.11 KNZ75538.1 - 7.9 5.8 9.7 0.093 12.2 0.4 2.5 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase HLH PF00010.26 KNZ75539.1 - 1.4e-13 50.5 0.1 3.4e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CCDC144C PF14915.6 KNZ75539.1 - 0.025 13.7 0.5 0.036 13.2 0.5 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF3138 PF11336.8 KNZ75539.1 - 0.071 11.7 0.1 0.071 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) ABATE PF07336.11 KNZ75539.1 - 4.5 8.0 13.3 1.2 9.9 0.7 2.6 2 1 0 2 2 2 0 Putative stress-induced transcription regulator Ldh_1_N PF00056.23 KNZ75540.1 - 2.8e-46 157.1 0.1 4.2e-46 156.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KNZ75540.1 - 6.2e-39 133.6 0.0 8.5e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KNZ75540.1 - 5.9e-05 22.2 0.0 0.00012 21.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ75540.1 - 0.091 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding CN_hydrolase PF00795.22 KNZ75542.1 - 2.2e-50 171.4 0.0 2.5e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Methyltransf_25 PF13649.6 KNZ75542.1 - 0.064 14.0 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ75542.1 - 0.072 13.7 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DIOX_N PF14226.6 KNZ75543.1 - 1.2e-12 48.6 0.0 2.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ75543.1 - 3.4e-11 43.5 0.0 6.2e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KNZ75544.1 - 2e-27 96.1 11.4 2.5e-27 95.8 11.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ75544.1 - 6.5e-06 25.3 2.1 1e-05 24.6 2.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter NADH-u_ox-rdase PF10785.9 KNZ75544.1 - 0.23 12.2 2.5 2.4 8.9 0.6 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Bap31 PF05529.12 KNZ75545.1 - 1.4e-44 151.3 5.7 2.1e-44 150.6 5.7 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KNZ75545.1 - 1.2e-11 44.4 4.4 1.2e-11 44.4 4.4 1.8 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain PI3K_P85_iSH2 PF16454.5 KNZ75545.1 - 0.0091 15.6 2.8 0.013 15.1 1.5 1.8 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1869 PF08956.10 KNZ75545.1 - 0.013 15.4 0.2 0.031 14.2 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1869) DUF1357 PF07094.11 KNZ75545.1 - 0.019 15.0 2.1 0.029 14.5 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Seryl_tRNA_N PF02403.22 KNZ75545.1 - 0.29 11.4 4.2 0.52 10.6 4.2 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3285 PF11688.8 KNZ75547.1 - 0.49 10.4 2.9 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) Membr_traf_MHD PF10540.9 KNZ75548.1 - 2e-24 86.5 0.5 5e-11 43.0 0.0 3.4 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 KNZ75548.1 - 3.2e-11 43.4 0.0 1.1e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 C2 domain HSP70 PF00012.20 KNZ75551.1 - 2.6e-75 253.8 5.0 2.6e-75 253.8 5.0 2.4 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KNZ75551.1 - 0.0038 16.1 2.1 0.019 13.8 2.2 2.0 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 KNZ75551.1 - 0.034 13.9 0.0 0.69 9.6 0.0 2.4 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 KNZ75551.1 - 0.083 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family CAML PF14963.6 KNZ75551.1 - 0.61 10.2 3.0 1.2 9.1 3.0 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF5529 PF17669.1 KNZ75552.1 - 0.0069 16.4 0.1 0.0089 16.1 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5529) HEAT_EZ PF13513.6 KNZ75553.1 - 3e-18 65.9 11.6 1.1e-12 48.1 0.0 7.3 9 0 0 9 9 9 2 HEAT-like repeat HEAT PF02985.22 KNZ75553.1 - 8.8e-13 47.3 14.2 6.7e-05 22.8 0.0 9.9 11 1 0 11 11 11 3 HEAT repeat IBN_N PF03810.19 KNZ75553.1 - 1.4e-11 44.2 2.1 7.5e-10 38.6 0.0 4.3 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 KNZ75553.1 - 4.5e-10 39.8 6.1 0.0039 17.6 0.0 7.1 4 1 2 6 6 6 4 HEAT repeats Arm PF00514.23 KNZ75553.1 - 3.4e-09 36.4 6.7 0.0018 18.3 0.0 6.7 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 KNZ75553.1 - 3.7e-05 23.7 0.8 0.78 9.6 0.0 4.6 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) MMS19_C PF12460.8 KNZ75553.1 - 0.00024 20.4 1.3 0.21 10.7 0.0 3.6 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 KNZ75553.1 - 0.00069 19.7 0.1 0.057 13.5 0.0 3.6 3 2 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 KNZ75553.1 - 0.003 17.1 0.1 29 4.1 0.0 4.5 2 2 3 5 5 5 0 CLASP N terminal LSM PF01423.22 KNZ75554.1 - 1.7e-19 69.3 0.0 2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 KNZ75554.1 - 0.16 12.1 0.1 0.73 10.0 0.1 1.8 1 1 0 2 2 2 0 RimP C-terminal SH3 domain PAP_assoc PF03828.19 KNZ75556.1 - 7.6e-15 54.9 0.1 1.8e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KNZ75556.1 - 2.3e-05 24.6 0.0 7.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KNZ75556.1 - 0.02 15.0 0.0 0.05 13.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Pan3_PK PF18101.1 KNZ75557.1 - 9.7e-65 216.7 0.1 1.5e-64 216.1 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KNZ75557.1 - 6.2e-07 29.0 0.0 3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75557.1 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short_C2 PF13561.6 KNZ75558.1 - 1.3e-50 172.2 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ75558.1 - 1.1e-37 129.4 0.2 1.4e-37 129.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ75558.1 - 2.9e-08 33.8 0.2 4e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 KR domain SET PF00856.28 KNZ75559.1 - 9.7e-15 55.4 0.0 2e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 SET domain HTH_21 PF13276.6 KNZ75559.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain Melibiase PF02065.18 KNZ75559.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 Melibiase UCH PF00443.29 KNZ75560.1 - 4.7e-38 131.2 0.0 6.5e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ75560.1 - 5.1e-10 39.4 0.0 2.2e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KNZ75560.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family TetR_C_3 PF08362.11 KNZ75562.1 - 0.0039 17.1 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 YcdC-like protein, C-terminal region zf-C4pol PF14260.6 KNZ75562.1 - 0.18 12.3 4.0 0.097 13.1 1.2 1.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Phage_Mu_Gam PF07352.12 KNZ75564.1 - 0.08 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein DUF680 PF05079.12 KNZ75568.1 - 0.11 13.2 0.7 0.26 12.0 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF680) RINGv PF12906.7 KNZ75569.1 - 1.9e-05 24.7 6.8 3.3e-05 23.9 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KNZ75569.1 - 0.0082 16.5 5.8 0.013 15.8 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain PHD_Oberon PF07227.11 KNZ75569.1 - 0.14 12.0 0.8 0.25 11.2 0.8 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein FANCL_C PF11793.8 KNZ75569.1 - 0.16 12.2 4.0 0.29 11.3 4.0 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KNZ75569.1 - 0.22 11.1 2.0 0.59 9.8 2.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD_4 PF16866.5 KNZ75569.1 - 2.9 8.0 7.2 6.6 6.9 5.6 2.0 2 0 0 2 2 2 0 PHD-finger Complex1_LYR PF05347.15 KNZ75571.1 - 4e-10 39.6 1.1 1.1e-09 38.2 1.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KNZ75571.1 - 4e-07 30.7 0.3 5.1e-07 30.3 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PP28 PF10252.9 KNZ75572.1 - 2.7e-25 88.6 30.2 4e-25 88.1 14.8 2.3 2 0 0 2 2 2 2 Casein kinase substrate phosphoprotein PP28 LAP1C PF05609.12 KNZ75572.1 - 4.4 6.3 15.7 5.3 6.0 15.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PPR_2 PF13041.6 KNZ75573.1 - 2.7e-07 30.7 0.0 0.00095 19.3 0.0 4.2 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 KNZ75573.1 - 0.0058 16.7 0.0 0.093 12.8 0.0 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 KNZ75573.1 - 0.027 14.7 0.1 3 8.3 0.1 2.9 2 0 0 2 2 2 0 PPR repeat PPR_1 PF12854.7 KNZ75573.1 - 0.14 11.9 0.0 1.8 8.3 0.0 2.7 3 0 0 3 3 3 0 PPR repeat RRM_1 PF00076.22 KNZ75574.1 - 1.5e-11 43.9 0.0 5e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KNZ75574.1 - 0.003 17.5 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KNZ75574.1 - 0.065 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif DUF5491 PF17595.2 KNZ75575.1 - 0.0034 17.6 0.0 0.029 14.7 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5491) rve PF00665.26 KNZ75576.1 - 0.0019 18.4 0.0 0.0024 18.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DUF5529 PF17669.1 KNZ75577.1 - 0.004 17.2 2.7 0.0059 16.7 2.7 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5529) Bac_RepA_C PF18008.1 KNZ75580.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain F-box-like PF12937.7 KNZ75582.1 - 0.0059 16.5 0.0 0.09 12.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ75582.1 - 0.016 15.0 0.0 0.062 13.2 0.0 2.0 1 0 0 1 1 1 0 F-box domain RasGEF PF00617.19 KNZ75583.1 - 1.9e-27 96.6 0.0 4.3e-26 92.2 0.0 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KNZ75583.1 - 3.3e-10 40.1 3.2 3.7e-10 40.0 1.6 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif ASF1_hist_chap PF04729.13 KNZ75584.1 - 4e-61 205.5 0.0 4.7e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone zf-primase PF09329.11 KNZ75585.1 - 0.074 12.9 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Primase zinc finger eIF2_C PF09173.11 KNZ75587.1 - 1.9e-34 117.8 0.7 4.4e-34 116.6 0.7 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KNZ75587.1 - 5.4e-20 71.8 1.1 9.4e-19 67.7 1.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KNZ75587.1 - 2e-11 44.1 1.5 3.5e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 KNZ75587.1 - 0.00046 20.1 0.7 0.039 13.9 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KNZ75587.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 KNZ75587.1 - 0.015 15.3 1.5 0.024 14.6 0.2 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Dak1_2 PF13684.6 KNZ75587.1 - 0.039 13.0 0.3 0.062 12.4 0.3 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family p450 PF00067.22 KNZ75588.1 - 1.6e-69 234.9 0.0 1.9e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRI PF08236.11 KNZ75589.1 - 2.8e-17 62.6 12.4 2.8e-17 62.6 12.4 2.2 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KNZ75589.1 - 2.6e-16 60.5 0.2 2.6e-16 60.5 0.2 3.5 2 2 0 2 2 2 1 SET domain AWS PF17907.1 KNZ75589.1 - 4.3e-13 49.1 9.6 4.3e-13 49.1 9.6 2.0 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KNZ75589.1 - 0.0077 16.2 2.0 0.38 10.8 0.1 3.5 3 0 0 3 3 3 1 TFIIS helical bundle-like domain RNA_pol_I_A49 PF06870.12 KNZ75590.1 - 2.7e-105 352.4 0.1 3.1e-105 352.2 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DapH_N PF08503.10 KNZ75590.1 - 0.011 15.9 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal Pkinase PF00069.25 KNZ75591.1 - 1.7e-26 93.1 0.0 7.2e-26 91.1 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75591.1 - 8e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ75591.1 - 7.3e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SOG2 PF10428.9 KNZ75591.1 - 0.0017 17.6 7.1 0.0023 17.2 7.1 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein APH PF01636.23 KNZ75591.1 - 0.07 13.0 1.1 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family BP28CT PF08146.12 KNZ75592.1 - 5.1e-25 88.2 0.6 1.8e-24 86.4 0.6 2.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KNZ75592.1 - 8.5e-16 58.3 14.8 1.5e-14 54.3 0.2 6.4 6 0 0 6 6 6 3 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KNZ75592.1 - 0.036 14.3 3.5 0.1 12.9 0.3 3.8 3 0 0 3 3 3 0 HEAT repeat PIF1 PF05970.14 KNZ75593.1 - 4.7e-20 72.1 0.0 5.7e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ75593.1 - 0.022 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ75593.1 - 0.028 14.2 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ75593.1 - 0.042 14.2 0.0 0.049 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KNZ75593.1 - 0.066 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KNZ75593.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DSX_dimer PF08828.10 KNZ75593.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Doublesex dimerisation domain Polyketide_cyc2 PF10604.9 KNZ75594.1 - 0.00045 20.5 0.0 0.0015 18.8 0.0 1.8 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport SUD-M PF11633.8 KNZ75594.1 - 0.028 14.1 0.1 0.48 10.1 0.1 2.1 2 0 0 2 2 2 0 Single-stranded poly(A) binding domain BAG PF02179.16 KNZ75595.1 - 1.3e-06 28.8 0.0 1.3e-06 28.8 0.0 2.7 2 1 0 2 2 2 1 BAG domain Ten_N PF06484.12 KNZ75595.1 - 0.011 15.6 4.8 0.014 15.4 4.8 1.3 1 0 0 1 1 1 0 Teneurin Intracellular Region HGTP_anticodon PF03129.20 KNZ75595.1 - 0.14 12.3 2.5 0.38 10.9 2.4 1.8 1 1 0 1 1 1 0 Anticodon binding domain Rrn6 PF10214.9 KNZ75595.1 - 0.5 8.8 17.6 0.64 8.4 17.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PRIMA1 PF16101.5 KNZ75595.1 - 1.4 9.0 8.4 5.2 7.1 8.0 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TMEM171 PF15471.6 KNZ75595.1 - 4 6.3 4.3 6.2 5.7 4.3 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Herpes_DNAp_acc PF04929.12 KNZ75595.1 - 5.4 5.9 14.8 7.9 5.3 14.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.9 KNZ75595.1 - 6.7 4.8 18.1 9.2 4.4 18.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 KNZ75595.1 - 7.1 5.2 7.0 8 5.0 7.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HCMV_UL124 PF17609.2 KNZ75596.1 - 0.0031 17.7 1.6 0.005 17.0 1.6 1.4 1 0 0 1 1 1 1 Family of unknown function DUF4328 PF14219.6 KNZ75596.1 - 0.0032 17.0 0.1 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) MscS_TM PF12794.7 KNZ75596.1 - 0.013 14.3 0.1 0.021 13.7 0.0 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 EVC2_like PF12297.8 KNZ75596.1 - 0.052 12.2 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF202 PF02656.15 KNZ75596.1 - 0.061 13.8 3.7 0.11 13.0 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Stevor PF17410.2 KNZ75596.1 - 0.16 11.5 0.1 0.28 10.7 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame GATase_5 PF13507.6 KNZ75597.1 - 4.7e-98 327.4 0.0 6.6e-98 326.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KNZ75597.1 - 2.8e-43 147.8 0.7 4.3e-29 101.7 0.2 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KNZ75597.1 - 4.9e-30 103.9 0.1 1.1e-29 102.8 0.0 1.7 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KNZ75597.1 - 8.8e-21 74.2 0.0 2.2e-20 72.9 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain APH PF01636.23 KNZ75599.1 - 1.7e-06 28.1 0.1 6.9e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KNZ75599.1 - 0.017 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KNZ75601.1 - 0.033 13.6 0.0 0.083 12.2 0.0 1.6 1 1 1 2 2 2 0 Protein kinase domain VP4_helical PF17478.2 KNZ75601.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Rotavirus VP4 helical domain RVP_2 PF08284.11 KNZ75602.1 - 4.4e-05 23.3 0.9 0.0018 18.1 0.1 2.2 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KNZ75602.1 - 0.021 15.4 0.0 0.037 14.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Lon_C PF05362.13 KNZ75604.1 - 5.2e-64 215.6 0.5 7.9e-64 215.0 0.5 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KNZ75604.1 - 2.8e-22 79.5 0.0 9.6e-22 77.8 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KNZ75604.1 - 8.4e-11 42.0 0.0 3.6e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 KNZ75604.1 - 8.6e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 KNZ75604.1 - 4.6e-06 26.5 0.0 1.7e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KNZ75604.1 - 0.00014 22.1 0.0 0.0005 20.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KNZ75604.1 - 0.00039 20.8 1.4 0.002 18.5 0.1 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 KNZ75604.1 - 0.00061 20.0 0.1 0.0065 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KNZ75604.1 - 0.0038 17.0 0.0 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KNZ75604.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KNZ75604.1 - 0.019 14.2 0.1 0.035 13.3 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KNZ75604.1 - 0.028 15.0 0.1 0.12 13.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 KNZ75604.1 - 0.037 14.3 4.6 0.36 11.1 0.4 3.8 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KNZ75604.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.22 KNZ75604.1 - 0.079 13.1 0.2 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase PSD5 PF07637.11 KNZ75604.1 - 0.1 13.0 0.2 0.26 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Mg_chelatase PF01078.21 KNZ75604.1 - 0.11 11.8 0.1 0.57 9.5 0.2 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KNZ75604.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KNZ75604.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FdhE PF04216.12 KNZ75604.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation CENP-H PF05837.12 KNZ75604.1 - 0.54 10.7 2.7 0.61 10.5 0.5 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SNF2_N PF00176.23 KNZ75605.1 - 9.8e-45 152.8 0.1 2.2e-44 151.6 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ75605.1 - 3.3e-19 69.2 0.0 8.4e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KNZ75605.1 - 1.2e-05 25.1 5.9 4.9e-05 23.1 5.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ75605.1 - 0.00012 22.0 1.1 0.00032 20.7 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ERCC3_RAD25_C PF16203.5 KNZ75605.1 - 0.00044 19.5 0.0 0.00084 18.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-RING_5 PF14634.6 KNZ75605.1 - 0.00058 19.8 5.5 0.0014 18.5 5.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 KNZ75605.1 - 0.0016 18.5 0.1 0.0064 16.5 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 KNZ75605.1 - 0.0023 18.1 2.6 0.0023 18.1 2.6 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KNZ75605.1 - 0.18 12.1 10.0 0.051 13.9 5.6 2.1 2 0 0 2 2 2 0 Ring finger domain IBR PF01485.21 KNZ75605.1 - 0.81 10.0 4.8 1.8 8.8 2.5 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Rad50_zn_hook PF04423.14 KNZ75605.1 - 3.2 7.7 6.5 0.2 11.5 0.1 2.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_2 PF13923.6 KNZ75605.1 - 7.3 6.5 15.1 0.032 14.1 5.8 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Cyclase PF04199.13 KNZ75606.1 - 1.4e-16 61.0 0.0 2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Glyco_hydro_3_C PF01915.22 KNZ75608.1 - 6.3e-52 176.5 0.0 1.1e-51 175.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ75608.1 - 4.6e-38 131.4 0.0 9.9e-38 130.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ75608.1 - 2.2e-19 69.3 0.0 3.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Ser_hydrolase PF06821.13 KNZ75608.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Glyco_hydro_3_C PF01915.22 KNZ75609.1 - 7.8e-51 172.9 0.0 1.2e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ75609.1 - 4.4e-40 138.0 0.0 9.5e-40 136.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain adh_short_C2 PF13561.6 KNZ75610.1 - 2.6e-40 138.5 0.0 3.1e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ75610.1 - 3.4e-35 121.3 0.1 5.1e-35 120.7 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KNZ75610.1 - 3.8e-08 33.5 0.0 1e-07 32.1 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ75610.1 - 0.00041 19.9 0.0 0.00075 19.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KNZ75610.1 - 0.0047 16.1 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KNZ75610.1 - 0.0049 16.8 0.1 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KNZ75610.1 - 0.036 13.2 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Virul_Fac PF10139.9 KNZ75610.1 - 0.037 12.3 0.0 0.051 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor YjeF_N PF03853.15 KNZ75610.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus GDP_Man_Dehyd PF16363.5 KNZ75610.1 - 0.084 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 KNZ75610.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B PF00753.27 KNZ75611.1 - 6.7e-08 32.8 0.4 1.4e-07 31.7 0.4 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily UQ_con PF00179.26 KNZ75612.1 - 5.6e-42 142.7 0.0 8.4e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PEMT PF04191.13 KNZ75613.1 - 2.6e-31 108.2 2.3 5e-31 107.2 2.3 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase ABC1 PF03109.16 KNZ75615.1 - 1e-23 83.8 0.0 1.7e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RRM_1 PF00076.22 KNZ75617.1 - 2e-25 88.4 0.1 3.4e-16 58.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KNZ75617.1 - 0.0075 16.5 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 KNZ75617.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Sugar_tr PF00083.24 KNZ75618.1 - 4.7e-81 273.0 19.2 5.7e-81 272.7 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ75618.1 - 4.7e-22 78.4 38.5 7.9e-16 57.9 7.9 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KNZ75618.1 - 0.0003 19.2 0.5 0.0003 19.2 0.5 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_16 PF10294.9 KNZ75619.1 - 0.016 15.0 0.2 0.02 14.6 0.2 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Endonuc_Holl PF10107.9 KNZ75619.1 - 0.085 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peroxidase_2 PF01328.17 KNZ75620.1 - 6.8e-38 131.1 0.0 1.1e-37 130.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 MSA-2c PF12238.8 KNZ75623.1 - 2.8 7.9 10.9 0.22 11.5 5.7 1.8 1 1 0 1 1 1 0 Merozoite surface antigen 2c Ank_2 PF12796.7 KNZ75624.1 - 1.4e-53 179.4 17.5 1.6e-19 70.3 3.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ75624.1 - 1.3e-48 162.4 25.7 1.9e-14 53.5 0.4 6.6 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ75624.1 - 1.8e-46 155.9 20.5 1.2e-13 51.3 0.5 7.2 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KNZ75624.1 - 4.1e-42 140.8 21.4 6.7e-08 32.6 1.0 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 KNZ75624.1 - 6e-40 130.7 11.9 9.3e-06 25.6 0.2 8.2 8 0 0 8 8 8 6 Ankyrin repeat TIMELESS PF04821.14 KNZ75624.1 - 0.021 14.1 0.0 0.052 12.8 0.0 1.6 1 0 0 1 1 1 0 Timeless protein ATP_bind_1 PF03029.17 KNZ75626.1 - 0.015 15.1 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF4751 PF15942.5 KNZ75626.1 - 0.032 14.2 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4751) Asp_protease_2 PF13650.6 KNZ75631.1 - 0.0069 17.0 0.0 0.0085 16.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KNZ75631.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KNZ75631.1 - 0.12 12.9 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ANAPC4_WD40 PF12894.7 KNZ75632.1 - 9.7e-14 51.4 0.0 3.3e-05 24.1 0.0 5.0 4 1 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ75632.1 - 0.0015 19.3 0.1 0.0015 19.3 0.1 6.0 6 1 0 6 6 6 1 WD domain, G-beta repeat Peptidase_S9_N PF02897.15 KNZ75632.1 - 0.12 11.1 0.0 0.27 10.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_1 PF00561.20 KNZ75633.1 - 1.3e-09 38.0 0.0 1.4e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75633.1 - 1.5e-07 32.3 0.0 1.5e-07 32.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ75633.1 - 0.0024 17.2 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 KNZ75633.1 - 0.074 12.8 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M41 PF01434.18 KNZ75634.1 - 1.3e-62 211.1 0.0 1.9e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KNZ75634.1 - 3.5e-42 143.9 0.0 7.1e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ75634.1 - 2.2e-12 46.6 0.2 5.7e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 KNZ75634.1 - 1.8e-09 37.9 0.0 5.3e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_16 PF13191.6 KNZ75634.1 - 0.00066 20.1 0.3 0.13 12.6 0.1 3.4 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 KNZ75634.1 - 0.0021 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 KNZ75634.1 - 0.04 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KNZ75634.1 - 0.042 14.1 0.1 1.8 8.8 0.1 2.6 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 KNZ75634.1 - 0.065 13.2 0.1 0.26 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNZ75634.1 - 0.091 12.9 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 KNZ75634.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Plasmodium_Vir PF05795.11 KNZ75634.1 - 0.12 11.8 5.3 0.18 11.2 5.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOG2 PF10428.9 KNZ75634.1 - 8.3 5.5 11.8 12 4.9 11.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 KNZ75634.1 - 8.3 5.0 6.4 12 4.5 6.4 1.2 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KNZ75635.1 - 6e-30 104.4 52.8 3.1e-28 98.7 30.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 KNZ75635.1 - 2.7e-05 23.8 4.1 5.4e-05 22.8 4.1 1.5 1 0 0 1 1 1 1 Nodulin-like MMPL PF03176.15 KNZ75635.1 - 0.043 12.7 1.4 0.092 11.7 1.4 1.6 1 0 0 1 1 1 0 MMPL family UreD PF01774.17 KNZ75636.1 - 2.5e-40 138.7 0.0 2e-37 129.2 0.0 2.0 1 1 0 1 1 1 1 UreD urease accessory protein GAGBD PF16828.5 KNZ75636.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 GAG-binding domain on surface antigen NRDE-2 PF08424.10 KNZ75638.1 - 3.3e-65 220.3 0.8 5.2e-65 219.7 0.8 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 KNZ75638.1 - 0.024 13.8 0.3 0.71 9.0 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75638.1 - 0.13 13.2 2.7 1.1e+02 4.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat UPF0113_N PF17833.1 KNZ75639.1 - 2.3e-29 101.8 0.0 3.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KNZ75639.1 - 8.3e-26 90.1 0.0 1.8e-25 89.0 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain HpuA PF16960.5 KNZ75639.1 - 0.21 10.7 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter Sec39 PF08314.11 KNZ75640.1 - 5.5e-95 319.4 0.0 7e-95 319.1 0.0 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 OHCU_decarbox PF09349.10 KNZ75640.1 - 0.18 12.3 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 OHCU decarboxylase Cgr1 PF03879.14 KNZ75642.1 - 7.6e-32 109.9 22.1 8.4e-32 109.8 22.1 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2570 PF10828.8 KNZ75642.1 - 0.035 13.9 5.1 0.044 13.6 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) MCU PF04678.13 KNZ75642.1 - 0.12 12.5 3.5 0.12 12.4 3.5 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Atg14 PF10186.9 KNZ75642.1 - 1.7 7.7 11.8 1.8 7.5 11.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Macoilin PF09726.9 KNZ75642.1 - 4.4 5.7 12.5 4.6 5.7 12.5 1.1 1 0 0 1 1 1 0 Macoilin family Pep3_Vps18 PF05131.14 KNZ75643.1 - 1.8e-51 173.9 0.0 3.5e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KNZ75643.1 - 1.2e-09 38.2 8.3 0.00033 20.5 1.0 3.8 3 2 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 KNZ75643.1 - 7.8e-07 29.5 0.1 1.7e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 KNZ75643.1 - 0.00056 19.7 2.0 0.00056 19.7 2.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ75643.1 - 0.00066 19.6 0.8 0.00066 19.6 0.8 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 KNZ75643.1 - 0.0049 17.2 1.9 0.0049 17.2 1.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 KNZ75643.1 - 0.0065 16.2 6.0 0.013 15.2 4.8 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KNZ75643.1 - 0.034 14.2 2.2 0.059 13.4 0.9 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KNZ75643.1 - 0.042 13.7 0.4 0.042 13.7 0.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NOG1_N PF17835.1 KNZ75643.1 - 0.07 13.1 0.3 0.14 12.1 0.3 1.4 1 0 0 1 1 1 0 NOG1 N-terminal helical domain Beta-lactamase2 PF13354.6 KNZ75643.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family zf-rbx1 PF12678.7 KNZ75643.1 - 0.46 10.8 2.7 0.6 10.5 0.3 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KNZ75643.1 - 0.57 9.8 4.4 0.24 11.1 1.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type TPR_2 PF07719.17 KNZ75643.1 - 8.3 6.8 5.6 9.7 6.6 0.5 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 KNZ75644.1 - 3.6e-29 101.9 0.0 1.7e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Spc7 PF08317.11 KNZ75645.1 - 0.0037 16.2 10.7 0.0037 16.2 10.7 6.9 1 1 5 7 7 7 3 Spc7 kinetochore protein DUF724 PF05266.14 KNZ75645.1 - 0.0054 16.6 7.9 0.0054 16.6 7.9 6.6 2 1 5 7 7 7 1 Protein of unknown function (DUF724) DUF4200 PF13863.6 KNZ75645.1 - 0.0056 17.1 4.2 0.0056 17.1 4.2 8.1 3 2 2 6 6 6 2 Domain of unknown function (DUF4200) Fez1 PF06818.15 KNZ75645.1 - 0.0082 16.6 6.1 0.0082 16.6 6.1 6.0 1 1 4 5 5 5 1 Fez1 BST2 PF16716.5 KNZ75645.1 - 0.0099 16.4 6.9 0.0099 16.4 6.9 9.4 3 2 7 10 10 10 3 Bone marrow stromal antigen 2 MatP_C PF17414.2 KNZ75645.1 - 0.031 14.5 0.9 0.031 14.5 0.9 4.1 4 0 0 4 4 4 0 MatP C-terminal ribbon-helix-helix domain Filament PF00038.21 KNZ75645.1 - 0.85 9.1 94.8 0.016 14.8 3.6 5.2 2 2 2 4 4 4 0 Intermediate filament protein ApoC-I PF04691.12 KNZ75645.1 - 1.4 8.9 7.2 0.14 12.1 0.6 2.9 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) DUF4407 PF14362.6 KNZ75645.1 - 7.2 5.9 86.5 0.18 11.1 4.9 5.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 KNZ75646.1 - 2.8e-25 88.1 6.6 6.6e-15 54.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mpv17_PMP22 PF04117.12 KNZ75647.1 - 3e-10 40.2 0.9 4.8e-10 39.5 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TRAPPC-Trs85 PF12739.7 KNZ75648.1 - 9.7e-36 123.6 0.0 8.8e-30 104.0 0.0 2.3 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit LCCL PF03815.19 KNZ75649.1 - 2.5e-11 43.5 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.14 KNZ75651.1 - 9.5e-14 52.0 0.0 1.6e-08 34.9 0.1 2.2 1 1 1 2 2 2 2 Putative adipose-regulatory protein (Seipin) SH3BGR PF04908.15 KNZ75652.1 - 1.8e-12 47.3 0.0 3.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DUF2559 PF10832.8 KNZ75652.1 - 0.01 15.9 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) PhetRS_B1 PF18262.1 KNZ75652.1 - 0.079 13.2 0.0 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain LMWPc PF01451.21 KNZ75653.1 - 1.6e-34 119.3 0.0 1.8e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase OmpH PF03938.14 KNZ75653.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Aldedh PF00171.22 KNZ75654.1 - 1.3e-106 356.9 0.1 2.7e-106 355.8 0.1 1.5 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KNZ75654.1 - 0.00043 19.4 0.1 0.00088 18.4 0.1 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Aldedh PF00171.22 KNZ75655.1 - 1.9e-128 428.9 0.1 2.1e-128 428.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KNZ75655.1 - 0.0009 18.4 0.0 0.0022 17.1 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1897 PF09005.10 KNZ75656.1 - 0.29 10.6 2.1 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) GDI PF00996.18 KNZ75657.1 - 9.6e-210 696.6 0.0 2.4e-209 695.3 0.0 1.5 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 KNZ75657.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Rav1p_C PF12234.8 KNZ75658.1 - 4.1e-192 640.0 0.0 8.4e-192 639.0 0.0 1.5 1 1 0 1 1 1 1 RAVE protein 1 C terminal Fasciclin PF02469.22 KNZ75659.1 - 9.8e-66 219.8 0.0 2.7e-18 66.4 0.1 5.5 5 0 0 5 5 5 5 Fasciclin domain Mito_carr PF00153.27 KNZ75659.1 - 4e-61 202.9 4.3 9.4e-20 70.3 0.2 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein NAT PF04768.13 KNZ75660.1 - 6e-34 117.1 0.0 8.2e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase UQ_con PF00179.26 KNZ75661.1 - 2e-18 66.4 0.0 3.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SKN1 PF03935.15 KNZ75662.1 - 6.6e-174 579.0 6.8 7.9e-174 578.7 6.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SNAPc_SNAP43 PF09808.9 KNZ75663.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ima1_N PF09779.9 KNZ75664.1 - 4e-32 111.9 0.7 6e-32 111.3 0.7 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain zinc_ribbon_6 PF14599.6 KNZ75664.1 - 1.4 9.0 5.4 0.16 12.0 0.7 1.9 2 0 0 2 2 2 0 Zinc-ribbon Rick_17kDa_Anti PF05433.15 KNZ75666.1 - 0.019 14.8 0.5 0.048 13.5 0.5 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Thiolase_N PF00108.23 KNZ75667.1 - 1.7e-68 230.8 0.2 2.4e-68 230.3 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNZ75667.1 - 4e-32 110.5 0.0 1.2e-31 109.0 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KNZ75667.1 - 9.9e-06 25.3 0.1 0.0059 16.4 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KNZ75667.1 - 0.00016 21.4 0.2 0.00061 19.4 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Glyco_transf_21 PF13506.6 KNZ75670.1 - 2.5e-22 79.2 0.2 8e-17 61.2 0.0 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KNZ75670.1 - 0.00035 20.5 0.0 0.00082 19.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Sec3_C PF09763.9 KNZ75671.1 - 1.6e-158 529.2 0.4 2.2e-158 528.8 0.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 KNZ75671.1 - 1.4e-20 73.2 0.0 3.6e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Mto2_bdg PF12808.7 KNZ75671.1 - 0.36 11.2 3.3 0.38 11.1 0.5 2.5 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region P16-Arc PF04699.14 KNZ75672.1 - 1.9e-51 174.4 0.0 2.2e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 KNZ75672.1 - 0.019 15.3 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF2711 PF10924.8 KNZ75672.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Zn_clus PF00172.18 KNZ75673.1 - 1.5e-05 25.0 8.8 2.7e-05 24.2 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNZ75673.1 - 0.0054 15.8 0.1 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain ThrE PF06738.12 KNZ75674.1 - 1e-46 159.3 6.1 1e-46 159.3 6.1 2.3 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 KNZ75674.1 - 3.6e-08 33.6 23.4 4.5e-08 33.3 7.0 3.0 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE APC_r PF05923.12 KNZ75674.1 - 3.6 7.4 4.9 0.66 9.8 0.6 2.1 2 0 0 2 2 2 0 APC repeat SNF2_N PF00176.23 KNZ75675.1 - 3.4e-66 223.3 0.0 5.2e-66 222.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ75675.1 - 1.8e-13 50.8 0.0 4.3e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KNZ75675.1 - 0.0012 18.8 0.3 0.0033 17.3 0.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ75675.1 - 0.012 15.7 0.4 0.044 13.8 0.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KNZ75675.1 - 0.023 14.6 0.7 0.023 14.6 0.7 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ75675.1 - 0.068 13.0 1.6 0.17 11.8 1.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ResIII PF04851.15 KNZ75675.1 - 0.12 12.4 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 KNZ75675.1 - 0.14 12.0 2.0 0.4 10.6 2.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MMR_HSR1 PF01926.23 KNZ75676.1 - 5.6e-16 58.6 0.0 1.2e-14 54.4 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ75676.1 - 4.6e-06 26.2 0.0 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KNZ75676.1 - 5.4e-06 26.4 0.1 0.001 19.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 KNZ75676.1 - 0.00037 19.9 0.0 0.00067 19.0 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KNZ75676.1 - 0.017 15.2 0.1 0.048 13.7 0.1 1.8 1 0 0 1 1 1 0 Dynamin family PPR_3 PF13812.6 KNZ75677.1 - 1.4e-11 44.3 0.3 0.00028 20.9 0.0 3.7 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 KNZ75677.1 - 2.1e-10 40.6 2.1 0.0055 16.9 0.0 5.8 5 2 2 7 7 7 4 PPR repeat family PPR PF01535.20 KNZ75677.1 - 9.9e-08 31.7 0.5 0.027 14.7 0.0 5.1 6 0 0 6 6 6 2 PPR repeat PPR_1 PF12854.7 KNZ75677.1 - 3.8e-06 26.5 0.6 0.016 14.9 0.0 3.3 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 KNZ75677.1 - 0.0054 16.1 0.0 3.1 7.1 0.0 2.2 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP Ribosomal_L3 PF00297.22 KNZ75678.1 - 2e-185 616.1 9.5 2.2e-185 615.9 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 SnoaL PF07366.12 KNZ75679.1 - 6.3e-08 32.5 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KNZ75679.1 - 1e-05 26.1 0.2 2.3e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 SnoaL-like domain Bystin PF05291.11 KNZ75680.1 - 7e-126 419.4 0.0 9e-126 419.1 0.0 1.1 1 0 0 1 1 1 1 Bystin Nop14 PF04147.12 KNZ75680.1 - 0.035 12.3 3.4 0.05 11.8 3.4 1.2 1 0 0 1 1 1 0 Nop14-like family GDP_Man_Dehyd PF16363.5 KNZ75681.1 - 5.9e-62 210.0 0.0 7.4e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KNZ75681.1 - 4.3e-47 160.6 0.0 5.9e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ75681.1 - 4.1e-10 39.1 0.0 6.7e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KNZ75681.1 - 5.9e-07 28.9 0.1 0.0044 16.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 KNZ75681.1 - 6.1e-07 28.8 0.0 8.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KNZ75681.1 - 3.8e-06 26.3 0.2 0.0033 16.6 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Abhydrolase_1 PF00561.20 KNZ75682.1 - 0.0027 17.4 0.1 0.024 14.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2458 PF10454.9 KNZ75683.1 - 5.3e-09 36.0 0.3 8.4e-09 35.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) RGS PF00615.19 KNZ75684.1 - 6e-43 145.9 0.5 1.6e-42 144.5 0.5 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KNZ75684.1 - 1.8e-15 56.7 0.0 4.2e-07 29.9 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cyt-b5 PF00173.28 KNZ75685.1 - 2.5e-10 40.3 0.1 4.2e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nup160 PF11715.8 KNZ75687.1 - 2.7e-25 89.0 0.0 5.5e-17 61.6 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Fungal_trans PF04082.18 KNZ75688.1 - 4.3e-16 58.7 1.4 8e-16 57.9 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ75688.1 - 3e-05 24.0 9.4 5.2e-05 23.3 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2263 PF10021.9 KNZ75689.1 - 9.7e-43 146.0 0.0 1.3e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) VSP PF03302.13 KNZ75690.1 - 3.3e-08 32.8 102.2 0.00044 19.2 16.2 5.9 1 1 4 5 5 5 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 KNZ75690.1 - 1.8e-07 31.2 27.2 4.8e-06 26.7 15.0 5.7 1 1 3 4 4 4 2 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 KNZ75690.1 - 0.01 15.6 92.2 0.014 15.2 26.0 4.1 1 1 1 3 3 3 0 Growth factor receptor domain IV AbrB PF05145.12 KNZ75690.1 - 0.044 12.7 0.2 0.062 12.2 0.2 1.1 1 0 0 1 1 1 0 Transition state regulatory protein AbrB DUF4381 PF14316.6 KNZ75690.1 - 0.054 13.7 0.4 0.084 13.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TMIE PF16038.5 KNZ75690.1 - 0.12 12.3 3.9 0.24 11.3 3.9 1.4 1 0 0 1 1 1 0 TMIE protein Vpu PF00558.19 KNZ75690.1 - 1 9.2 2.2 0.99 9.2 0.5 1.7 2 0 0 2 2 2 0 Vpu protein Furin-like PF00757.20 KNZ75690.1 - 8.5 6.2 87.7 0.078 12.8 31.7 4.7 1 1 3 4 4 4 0 Furin-like cysteine rich region TPR_1 PF00515.28 KNZ75691.1 - 6.5e-41 136.5 21.0 8e-05 22.3 1.1 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ75691.1 - 1.3e-35 118.6 26.5 0.00019 21.3 0.0 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat STI1 PF17830.1 KNZ75691.1 - 1.4e-35 121.0 9.1 5.7e-18 64.6 0.1 3.0 3 0 0 3 3 2 2 STI1 domain TPR_16 PF13432.6 KNZ75691.1 - 5.6e-24 84.5 13.5 1.9e-07 31.6 0.1 6.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ75691.1 - 7.5e-21 74.2 17.8 2.4e-11 43.8 0.3 7.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ75691.1 - 3.7e-20 71.3 18.5 5.3e-06 26.0 0.2 7.7 6 2 1 7 7 7 6 TPR repeat TPR_8 PF13181.6 KNZ75691.1 - 5e-18 63.7 25.6 0.00029 20.8 0.4 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75691.1 - 2.1e-16 59.2 12.3 0.31 12.0 0.0 8.2 5 2 4 9 9 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ75691.1 - 3.8e-15 56.1 12.6 5.3e-08 33.3 0.1 6.9 3 2 2 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ75691.1 - 8.3e-15 53.7 6.9 0.00067 19.5 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ75691.1 - 1.9e-12 46.7 7.0 0.0079 16.5 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ75691.1 - 1e-08 34.7 17.0 0.00089 19.1 0.0 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ75691.1 - 9.9e-08 32.2 15.8 0.59 10.9 0.0 8.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ75691.1 - 6.3e-05 23.1 4.4 3.8 7.7 0.0 5.0 3 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ75691.1 - 0.0009 19.4 11.0 0.043 14.0 0.6 5.8 3 3 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 KNZ75691.1 - 0.0011 19.0 16.6 2 8.5 0.1 7.4 8 0 0 8 8 8 2 MIT (microtubule interacting and transport) domain BTAD PF03704.17 KNZ75691.1 - 0.0032 17.9 10.0 2.3 8.7 0.5 4.5 4 1 0 4 4 4 1 Bacterial transcriptional activator domain DUF627 PF04781.12 KNZ75691.1 - 0.0067 16.4 3.3 4.8 7.2 0.5 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF627) TPR_4 PF07721.14 KNZ75691.1 - 0.02 15.5 0.0 0.53 11.1 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat XPC-binding PF09280.11 KNZ75691.1 - 0.036 13.8 4.4 1.1 9.1 1.0 2.7 2 0 0 2 2 2 0 XPC-binding domain TPR_3 PF07720.12 KNZ75691.1 - 0.042 13.8 19.1 1.6 8.8 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 KNZ75691.1 - 0.057 13.7 0.3 39 4.8 0.0 4.4 4 1 0 4 4 4 0 PPR repeat DUF357 PF04010.13 KNZ75691.1 - 0.1 12.7 3.2 0.27 11.3 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF357) TPR_20 PF14561.6 KNZ75691.1 - 0.38 11.1 12.3 5.9 7.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 KNZ75691.1 - 0.5 10.4 9.4 25 4.9 0.2 4.8 3 3 1 4 4 4 0 Domain of Unknown Function (DUF3856) Alkyl_sulf_dimr PF14863.6 KNZ75691.1 - 2.9 8.3 8.9 17 5.9 0.0 3.8 3 1 0 4 4 3 0 Alkyl sulfatase dimerisation Adap_comp_sub PF00928.21 KNZ75692.1 - 5.6e-55 186.6 0.0 8.2e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KNZ75692.1 - 3.8e-05 23.6 0.0 7.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldo_ket_red PF00248.21 KNZ75693.1 - 3.1e-38 131.6 0.0 4.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1543 PF07566.12 KNZ75693.1 - 0.22 11.3 0.0 0.48 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) B12D PF06522.11 KNZ75694.1 - 3e-15 55.8 0.1 4.1e-15 55.3 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX7a PF02238.15 KNZ75694.1 - 0.17 12.3 1.5 0.25 11.8 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Cnn_1N PF07989.11 KNZ75695.1 - 0.19 11.9 3.2 3.2 8.0 0.1 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 KNZ75695.1 - 0.72 10.0 8.5 0.045 14.0 1.2 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.9 KNZ75695.1 - 3.2 7.6 6.8 4.9 7.1 0.1 2.5 1 1 0 2 2 2 0 Axonemal dynein light chain Isochorismatase PF00857.20 KNZ75696.1 - 4.1e-15 56.4 0.0 2.4e-14 53.9 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_3 PF00933.21 KNZ75698.1 - 1e-35 123.6 0.0 1.7e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KNZ75698.1 - 1.8e-26 93.4 0.2 3.2e-26 92.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain rve PF00665.26 KNZ75698.1 - 0.0021 18.2 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain UPF0147 PF03685.13 KNZ75699.1 - 0.017 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) TFIIA PF03153.13 KNZ75700.1 - 0.013 15.6 8.3 0.016 15.2 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_Helicase PF02689.14 KNZ75701.1 - 5.6e-07 27.9 0.0 6.4e-07 27.7 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ75701.1 - 0.0037 17.0 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Glyco_hydro_3_C PF01915.22 KNZ75702.1 - 6.6e-49 166.6 0.1 1.1e-48 165.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ75702.1 - 6e-34 117.8 0.0 1.1e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ75702.1 - 0.00028 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 KNZ75702.1 - 0.077 12.0 0.7 0.12 11.3 0.7 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Helitron_like_N PF14214.6 KNZ75703.1 - 6e-61 206.0 0.3 7.1e-61 205.7 0.3 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ75703.1 - 0.0061 15.7 0.1 0.0073 15.4 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) DUF3584 PF12128.8 KNZ75705.1 - 0.0019 15.9 33.7 0.0025 15.4 33.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SLATT_6 PF18169.1 KNZ75705.1 - 0.17 11.4 3.2 0.35 10.4 3.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Hemagglutinin PF00509.18 KNZ75705.1 - 0.28 9.5 2.5 0.38 9.1 2.5 1.2 1 0 0 1 1 1 0 Haemagglutinin CALCOCO1 PF07888.11 KNZ75705.1 - 0.43 9.4 37.4 0.74 8.6 37.4 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 KNZ75705.1 - 0.44 9.4 39.4 0.07 12.0 26.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Glyco_hydro_47 PF01532.20 KNZ75707.1 - 5.3e-143 477.2 0.2 6.1e-143 477.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 KNZ75707.1 - 0.0049 16.4 0.5 0.57 9.6 0.0 3.4 3 1 0 3 3 3 1 D-glucuronyl C5-epimerase C-terminus Chs7 PF12271.8 KNZ75708.1 - 1.3e-114 382.5 23.2 1.5e-114 382.3 23.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KNZ75708.1 - 0.56 10.5 6.2 0.34 11.2 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) PS_Dcarbxylase PF02666.15 KNZ75709.1 - 3.2e-72 242.3 0.0 8.2e-70 234.4 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 KNZ75709.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit SPO22 PF08631.10 KNZ75710.1 - 5.1e-65 219.7 13.0 5.1e-62 209.9 3.2 3.5 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like ANAPC3 PF12895.7 KNZ75710.1 - 6.4e-05 23.1 0.9 0.07 13.4 0.0 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KNZ75710.1 - 0.0031 18.0 2.9 0.084 13.4 0.1 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ75710.1 - 0.077 13.1 2.3 28 5.1 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ75710.1 - 0.099 12.5 0.3 25 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75710.1 - 0.1 13.5 16.2 0.56 11.2 0.3 6.7 8 1 1 9 9 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ75710.1 - 0.11 12.7 9.3 5.5 7.3 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TetR_C_35 PF18556.1 KNZ75710.1 - 0.14 12.3 2.0 0.5 10.5 0.4 2.8 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain TPR_6 PF13174.6 KNZ75710.1 - 0.21 12.3 1.1 26 5.7 0.3 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ75710.1 - 0.48 11.1 11.4 1.4 9.7 1.7 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ75710.1 - 1.4 9.8 6.2 0.42 11.4 0.5 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ75710.1 - 1.7 9.0 10.0 4.3 7.7 0.2 5.2 4 2 0 4 4 4 0 Tetratricopeptide repeat Cullin PF00888.22 KNZ75711.1 - 4.8e-130 435.1 1.6 6.6e-130 434.6 1.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KNZ75711.1 - 1.3e-22 79.6 0.1 3.3e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF515 PF04415.12 KNZ75711.1 - 0.008 14.6 0.3 0.014 13.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF515) TRAPP PF04051.16 KNZ75712.1 - 9.7e-35 119.4 0.0 1.7e-34 118.7 0.0 1.4 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3752 PF12572.8 KNZ75713.1 - 2.1e-41 142.0 4.6 2.1e-41 142.0 4.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Retrotran_gag_2 PF14223.6 KNZ75715.1 - 1.1e-05 25.1 0.3 0.0087 15.7 0.0 2.2 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF3549 PF12069.8 KNZ75715.1 - 0.16 11.0 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Baculo_E56 PF04639.12 KNZ75715.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Abhydrolase_1 PF00561.20 KNZ75716.1 - 9.4e-42 143.4 0.0 1.9e-41 142.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75716.1 - 0.0058 17.3 4.7 0.015 15.9 4.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Rgp1 PF08737.10 KNZ75718.1 - 7.8e-47 160.4 0.0 1.7e-46 159.3 0.0 1.6 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 KNZ75718.1 - 0.00027 21.4 0.0 0.32 11.5 0.0 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KNZ75718.1 - 0.0083 16.2 0.0 2.8 8.0 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain p450 PF00067.22 KNZ75719.1 - 6e-42 144.0 0.0 6.9e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Rapsyn_N PF10579.9 KNZ75719.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region A_deaminase PF00962.22 KNZ75720.1 - 2.3e-20 73.2 0.0 4.6e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase F-box-like PF12937.7 KNZ75721.1 - 4.2e-05 23.4 0.1 0.00015 21.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ75721.1 - 0.0021 17.9 0.2 0.0071 16.2 0.2 1.9 1 0 0 1 1 1 1 F-box domain Tryp_alpha_amyl PF00234.22 KNZ75721.1 - 0.092 13.2 0.2 0.2 12.1 0.2 1.6 1 1 0 1 1 1 0 Protease inhibitor/seed storage/LTP family COesterase PF00135.28 KNZ75722.1 - 6.6e-78 262.8 0.0 8.6e-69 232.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ75722.1 - 4.9e-10 39.6 0.2 6.7e-09 35.9 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75722.1 - 0.0033 18.0 0.7 0.0086 16.7 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KNZ75722.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short_C2 PF13561.6 KNZ75723.1 - 1.2e-52 178.8 3.4 8.2e-42 143.4 1.9 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ75723.1 - 3.9e-46 157.0 1.7 4.7e-46 156.7 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ75723.1 - 1e-14 54.9 0.1 1.7e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KNZ75723.1 - 0.0035 17.2 1.1 0.0055 16.6 1.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KNZ75723.1 - 0.03 15.0 0.2 0.063 14.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 KNZ75723.1 - 0.067 13.3 0.9 0.13 12.4 0.9 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain SKG6 PF08693.10 KNZ75725.1 - 0.063 12.7 0.3 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KNZ75725.1 - 0.12 12.1 1.8 0.21 11.4 1.8 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phage_HK97_TLTM PF06120.11 KNZ75725.1 - 0.27 10.4 0.1 0.38 9.9 0.1 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Retrotran_gag_2 PF14223.6 KNZ75726.1 - 1.3e-08 34.6 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KNZ75726.1 - 0.005 16.5 0.4 0.014 15.1 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Phage_HK97_TLTM PF06120.11 KNZ75727.1 - 0.066 12.4 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Phage_HK97_TLTM PF06120.11 KNZ75728.1 - 0.0021 17.3 0.2 0.003 16.8 0.2 1.1 1 0 0 1 1 1 1 Tail length tape measure protein SKG6 PF08693.10 KNZ75728.1 - 0.014 14.8 0.3 0.024 14.0 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Bromodomain PF00439.25 KNZ75729.1 - 3.1e-22 78.4 0.0 9.3e-15 54.5 0.0 2.7 3 0 0 3 3 3 2 Bromodomain BAH PF01426.18 KNZ75729.1 - 9e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 BAH domain zf-C2H2 PF00096.26 KNZ75730.1 - 2.5e-08 33.9 6.6 0.00012 22.3 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ75730.1 - 2.4e-05 24.6 0.4 2.4e-05 24.6 0.4 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ75730.1 - 0.00028 21.4 7.5 0.041 14.7 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KNZ75730.1 - 0.00093 18.9 0.4 0.94 9.3 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 KNZ75730.1 - 0.016 15.1 1.8 0.016 15.1 1.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KNZ75730.1 - 0.069 13.2 0.2 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KNZ75730.1 - 0.096 12.5 1.4 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 zinc-finger C2H2-type Caleosin PF05042.13 KNZ75732.1 - 1.1e-59 201.2 0.2 1.3e-59 200.9 0.2 1.0 1 0 0 1 1 1 1 Caleosin related protein ArfA PF03889.13 KNZ75732.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A adh_short PF00106.25 KNZ75733.1 - 1.1e-07 31.6 0.0 4.2e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KNZ75733.1 - 0.033 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein KR PF08659.10 KNZ75733.1 - 0.036 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 KNZ75733.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FKBP_C PF00254.28 KNZ75734.1 - 2.2e-32 111.2 0.0 2.6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glyco_transf_25 PF01755.17 KNZ75735.1 - 1.3e-05 25.1 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) OPT PF03169.15 KNZ75736.1 - 2.8e-158 528.3 44.8 2.1e-137 459.4 34.8 3.0 2 1 0 2 2 2 2 OPT oligopeptide transporter protein Pox_P35 PF03213.14 KNZ75737.1 - 0.051 12.8 0.6 0.068 12.4 0.6 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein FliD_N PF02465.18 KNZ75737.1 - 0.29 11.8 3.0 0.18 12.5 0.6 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mitoc_mL59 PF18126.1 KNZ75737.1 - 0.34 11.2 5.8 0.46 10.8 5.8 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 TPR_10 PF13374.6 KNZ75737.1 - 1.1 9.3 6.3 7.8 6.5 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat 5_nucleotid PF05761.14 KNZ75737.1 - 1.1 8.0 5.7 1.3 7.8 5.7 1.2 1 0 0 1 1 1 0 5' nucleotidase family Exonuc_VII_L PF02601.15 KNZ75737.1 - 2.1 7.9 9.2 2.6 7.5 9.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 KNZ75737.1 - 6.1 6.7 10.5 0.21 11.4 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) GFA PF04828.14 KNZ75738.1 - 1.6e-33 114.9 1.1 2.7e-21 75.7 1.1 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme OTT_1508_deam PF14441.6 KNZ75740.1 - 2.2e-09 37.2 1.2 5.4e-09 35.9 1.2 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Sua5_yciO_yrdC PF01300.18 KNZ75740.1 - 0.18 11.3 0.0 1.6 8.2 0.0 2.0 2 0 0 2 2 2 0 Telomere recombination TMEM154 PF15102.6 KNZ75742.1 - 0.073 13.0 0.6 0.14 12.0 0.6 1.7 1 1 0 1 1 1 0 TMEM154 protein family ATP-synt_Z PF16594.5 KNZ75742.1 - 0.11 11.9 1.0 0.19 11.3 1.0 1.3 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated AA_permease_2 PF13520.6 KNZ75743.1 - 3.5e-46 157.9 52.7 4.2e-46 157.6 52.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ75743.1 - 8.3e-08 31.2 48.6 1.5e-07 30.4 48.5 1.4 1 1 0 1 1 1 1 Amino acid permease PIF1 PF05970.14 KNZ75746.1 - 2.6e-39 135.4 0.0 3.4e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ75746.1 - 0.0024 17.9 0.0 0.0083 16.1 0.0 1.7 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ75746.1 - 0.0025 17.6 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ75746.1 - 0.012 16.0 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ75746.1 - 0.015 15.0 0.1 0.038 13.7 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.8 KNZ75746.1 - 0.067 12.0 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.22 KNZ75746.1 - 0.09 13.2 0.1 0.52 10.7 0.1 2.2 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KNZ75746.1 - 0.099 12.2 0.2 0.16 11.5 0.2 1.4 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 KNZ75746.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin Herpes_Helicase PF02689.14 KNZ75747.1 - 6.7e-05 21.0 0.1 7.2e-05 20.9 0.1 1.0 1 0 0 1 1 1 1 Helicase dTDP_sugar_isom PF00908.17 KNZ75747.1 - 0.056 13.1 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase TyeA PF09059.10 KNZ75750.1 - 0.028 14.5 0.2 0.04 14.0 0.2 1.2 1 0 0 1 1 1 0 TyeA DnaJ PF00226.31 KNZ75751.1 - 1.1e-17 63.8 1.4 1.2e-17 63.7 0.1 1.8 2 0 0 2 2 1 1 DnaJ domain TPR_2 PF07719.17 KNZ75751.1 - 3e-15 55.0 0.5 0.00017 21.4 0.0 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ75751.1 - 8.4e-13 47.6 0.0 0.00021 20.9 0.0 4.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ75751.1 - 1.3e-10 41.6 1.1 0.0043 17.5 0.2 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ75751.1 - 7.8e-10 38.7 7.3 0.012 16.4 0.1 6.5 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ75751.1 - 1.7e-09 38.1 6.7 1.2e-05 25.8 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ75751.1 - 2.7e-09 36.5 0.7 7.4e-06 25.6 0.6 2.9 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 KNZ75751.1 - 1.9e-07 31.3 2.8 0.22 11.8 0.1 4.1 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ75751.1 - 5.3e-07 29.2 2.4 0.01 15.8 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ75751.1 - 1.9e-06 27.6 0.1 0.32 11.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ75751.1 - 2.6e-06 27.4 2.7 0.015 15.6 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ75751.1 - 5.1e-06 26.8 0.7 20 6.1 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ75751.1 - 1.2e-05 25.5 5.0 0.81 10.5 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ75751.1 - 0.0001 22.1 4.8 0.42 10.6 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ75751.1 - 0.00025 21.1 6.2 9.8 6.4 0.0 5.4 3 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ75751.1 - 0.00099 19.3 1.4 1.8 8.8 0.1 4.5 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 KNZ75751.1 - 0.022 15.2 2.8 0.74 10.2 0.0 3.9 3 2 0 4 4 4 0 Bacterial transcriptional activator domain PknG_TPR PF16918.5 KNZ75751.1 - 0.026 13.3 0.2 0.39 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat SLT_L PF14718.6 KNZ75751.1 - 0.13 12.4 0.0 8.4 6.6 0.0 2.6 2 0 0 2 2 2 0 Soluble lytic murein transglycosylase L domain MIT PF04212.18 KNZ75751.1 - 0.3 11.2 2.0 1.5 9.0 0.0 3.1 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain OTT_1508_deam PF14441.6 KNZ75752.1 - 1.7e-09 37.5 0.1 4.6e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase OTT_1508_deam PF14441.6 KNZ75753.1 - 2.6e-07 30.5 0.2 8.2e-07 28.9 0.2 1.9 1 0 0 1 1 1 1 OTT_1508-like deaminase SR1P PF13790.6 KNZ75753.1 - 6.1 7.0 7.3 14 5.9 3.0 2.8 3 0 0 3 3 3 0 SR1 protein Cu-oxidase PF00394.22 KNZ75754.1 - 2.8e-49 167.3 0.1 1.2e-47 162.0 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ75754.1 - 3.5e-32 111.0 0.1 1.2e-31 109.3 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase ChitinaseA_N PF08329.10 KNZ75754.1 - 0.14 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Glyco_hydro_31 PF01055.26 KNZ75758.1 - 1.7e-139 465.8 4.5 2.8e-139 465.1 4.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KNZ75758.1 - 3.1e-16 59.4 0.1 9.5e-16 57.9 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 KNZ75758.1 - 1.7e-05 25.0 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Gb3_synth PF04572.12 KNZ75758.1 - 0.0042 17.3 0.4 0.0092 16.2 0.4 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region MFS_1 PF07690.16 KNZ75759.1 - 2.5e-30 105.6 9.5 2.5e-30 105.6 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ75759.1 - 3.3e-10 39.4 9.9 4.7e-10 38.9 9.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KNZ75759.1 - 2.5e-07 29.5 2.7 3.1e-07 29.2 2.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KNZ75759.1 - 0.12 10.9 10.1 0.53 8.8 2.6 2.1 1 1 1 2 2 2 0 MFS/sugar transport protein EthD PF07110.11 KNZ75760.1 - 0.021 16.0 0.1 0.069 14.3 0.1 1.9 1 1 0 1 1 1 0 EthD domain DUF4286 PF14114.6 KNZ75760.1 - 0.066 13.7 0.6 0.1 13.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) FTSW_RODA_SPOVE PF01098.19 KNZ75763.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Cell cycle protein SKN1 PF03935.15 KNZ75764.1 - 1.7e-173 577.7 7.5 4.1e-172 573.1 7.5 2.0 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DSPc PF00782.20 KNZ75765.1 - 4.1e-30 104.3 0.0 4.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ75765.1 - 4.5e-05 23.1 0.0 5.5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 KNZ75765.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Sld7_C PF18596.1 KNZ75766.1 - 0.0033 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain TPK_B1_binding PF04265.14 KNZ75769.1 - 0.049 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, vitamin B1 binding domain DnaJ PF00226.31 KNZ75770.1 - 2.4e-11 43.6 0.0 4.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain zf-H3C2 PF16721.5 KNZ75770.1 - 0.17 12.3 0.2 18 5.8 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding Rit1_C PF17184.4 KNZ75771.1 - 1.1e-96 323.5 0.0 1.6e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KNZ75771.1 - 7.8e-14 51.9 0.0 2.7e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Rit1 DUSP-like domain SET PF00856.28 KNZ75772.1 - 2.3e-13 50.9 0.0 4.8e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 SET domain SAF PF08666.12 KNZ75772.1 - 0.024 15.3 0.0 5.9 7.6 0.0 2.4 2 0 0 2 2 2 0 SAF domain Calpain_III PF01067.22 KNZ75773.1 - 8.8e-15 55.2 0.1 0.00031 21.0 0.0 4.3 4 1 0 4 4 4 3 Calpain large subunit, domain III Peptidase_C2 PF00648.21 KNZ75773.1 - 8.5e-12 44.7 0.0 2e-11 43.5 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease MIT PF04212.18 KNZ75773.1 - 0.00043 20.3 1.6 0.00068 19.6 1.6 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 KNZ75774.1 - 5.2e-09 35.9 0.1 8.4e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75774.1 - 0.00011 21.6 0.1 0.00016 21.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ75774.1 - 0.00019 20.9 0.1 0.00043 19.7 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ75774.1 - 0.0017 18.4 0.0 0.0089 16.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4336 PF14234.6 KNZ75774.1 - 0.042 13.0 0.0 0.07 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) Fmp27_WPPW PF10359.9 KNZ75776.1 - 0.0024 16.8 0.3 0.0035 16.3 0.3 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain BPS1 PF05633.11 KNZ75776.1 - 0.0054 15.8 0.1 0.0097 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein BYPASS1-related DUF2664 PF10867.8 KNZ75776.1 - 0.008 16.6 3.2 0.022 15.2 3.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2664) DUF641 PF04859.12 KNZ75776.1 - 0.0081 16.5 1.0 0.0081 16.5 1.0 2.2 3 0 0 3 3 3 1 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.9 KNZ75776.1 - 0.62 10.4 3.8 0.63 10.4 0.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec2p PF06428.11 KNZ75776.1 - 0.95 9.5 5.4 0.63 10.0 1.6 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1963 PF09234.10 KNZ75777.1 - 0.012 16.1 0.2 0.014 15.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) zf-CCCH_6 PF18585.1 KNZ75778.1 - 0.063 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Pkinase PF00069.25 KNZ75779.1 - 7.3e-10 38.6 0.0 7.6e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75779.1 - 5e-05 22.7 0.0 0.0033 16.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KNZ75779.1 - 0.22 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 KNZ75780.1 - 1.7e-09 37.4 0.0 4.7e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75780.1 - 1.2e-05 24.8 0.0 0.00094 18.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Arm-DNA-bind_4 PF14657.6 KNZ75783.1 - 0.15 11.8 0.3 0.27 11.0 0.3 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain 2OG-FeII_Oxy PF03171.20 KNZ75784.1 - 4.3e-15 56.0 0.0 9.8e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KNZ75784.1 - 4.6e-14 53.2 0.2 1.1e-13 52.0 0.2 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Zn_clus PF00172.18 KNZ75785.1 - 0.014 15.5 5.1 0.18 12.0 1.3 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3602 PF12223.8 KNZ75789.1 - 2.6e-21 76.0 37.1 2.1e-07 31.5 3.8 6.1 2 1 4 6 6 6 6 Protein of unknown function (DUF3602) UPF0147 PF03685.13 KNZ75793.1 - 0.068 13.2 0.0 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Oxidored_FMN PF00724.20 KNZ75794.1 - 5.3e-18 65.4 0.0 6.2e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DIOX_N PF14226.6 KNZ75795.1 - 2.5e-20 73.4 0.0 4.6e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ75795.1 - 8.3e-14 51.9 0.0 1.6e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3287 PF11690.8 KNZ75796.1 - 0.0095 15.7 5.1 0.013 15.2 4.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3287) CENP-H PF05837.12 KNZ75796.1 - 0.012 16.0 4.9 0.019 15.4 4.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KNZ75796.1 - 0.04 14.5 1.4 0.067 13.7 1.4 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ERM PF00769.19 KNZ75796.1 - 0.26 11.1 11.0 0.45 10.3 11.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4200 PF13863.6 KNZ75796.1 - 1.5 9.2 7.4 2.3 8.7 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DAHP_synth_2 PF01474.16 KNZ75798.1 - 1e-190 633.9 0.0 1.1e-190 633.8 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family GST_N PF02798.20 KNZ75799.1 - 2.6e-17 62.9 0.0 4.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KNZ75799.1 - 3.6e-17 62.5 0.0 6.1e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ75799.1 - 2.7e-12 46.7 0.0 4.3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KNZ75799.1 - 5.3e-10 39.5 0.0 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ75799.1 - 6.7e-07 29.2 0.0 8.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ75799.1 - 2.1e-05 24.6 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GMP_synt_C PF00958.22 KNZ75799.1 - 0.047 13.7 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 GMP synthase C terminal domain motB PF17613.2 KNZ75799.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Modifier of transcription F-box-like PF12937.7 KNZ75800.1 - 0.0012 18.6 5.3 0.0025 17.7 1.8 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KNZ75800.1 - 0.0053 16.6 2.1 0.0053 16.6 2.1 2.7 3 0 0 3 3 3 1 F-box domain PRANC PF09372.10 KNZ75800.1 - 0.11 12.9 0.2 1.9 8.9 0.1 2.4 2 0 0 2 2 2 0 PRANC domain ECH_1 PF00378.20 KNZ75801.1 - 1.9e-28 99.4 0.1 2.7e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ75801.1 - 2.8e-16 59.9 1.1 3e-13 50.0 0.3 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase YABBY PF04690.13 KNZ75803.1 - 0.002 18.7 4.0 0.002 18.7 4.0 1.6 1 1 1 2 2 2 1 YABBY protein HMG_box PF00505.19 KNZ75803.1 - 0.0059 17.0 3.7 0.0059 17.0 3.7 1.7 1 1 1 2 2 2 1 HMG (high mobility group) box MHC_I_3 PF16497.5 KNZ75806.1 - 0.1 12.1 0.3 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 MHC-I family domain Tannase PF07519.11 KNZ75807.1 - 3.3e-94 316.5 0.0 4.1e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 KNZ75807.1 - 0.00057 19.6 0.0 0.0029 17.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ75807.1 - 0.0013 18.1 0.0 0.054 12.8 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 ATG7_N PF16420.5 KNZ75809.1 - 1.9e-91 306.8 0.0 2.6e-91 306.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KNZ75809.1 - 6.9e-46 156.6 0.0 1.1e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KNZ75809.1 - 0.11 12.6 0.0 0.46 10.5 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Terpene_synth_C PF03936.16 KNZ75810.1 - 4e-10 39.5 0.0 5.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF5601 PF18151.1 KNZ75810.1 - 0.0017 18.6 0.1 0.21 11.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5601) MIS13 PF08202.11 KNZ75812.1 - 2e-22 79.8 5.2 5e-21 75.3 5.2 2.3 1 1 0 1 1 1 1 Mis12-Mtw1 protein family Polysacc_deac_1 PF01522.21 KNZ75814.1 - 1.8e-24 86.0 0.3 3.9e-24 84.9 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase DUF1752 PF08550.10 KNZ75815.1 - 5.6e-13 48.5 0.4 1.2e-12 47.4 0.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.8 KNZ75815.1 - 6.5e-11 42.3 3.8 6.5e-11 42.3 3.8 4.1 3 1 2 5 5 5 1 Protein of unknown function (DUF3295) Fungal_trans PF04082.18 KNZ75816.1 - 4.2e-26 91.6 0.0 7.9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ75816.1 - 0.0031 17.6 9.1 0.0062 16.6 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.21 KNZ75817.1 - 6.4e-22 77.8 0.1 1.3e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase DHHC PF01529.20 KNZ75818.1 - 8.8e-32 110.0 7.6 8.8e-32 110.0 7.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase FYVE PF01363.21 KNZ75818.1 - 0.2 11.8 7.2 0.41 10.8 7.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger OrfB_Zn_ribbon PF07282.11 KNZ75818.1 - 0.43 10.5 4.4 0.94 9.4 4.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 KNZ75818.1 - 1.5 8.3 5.7 0.71 9.4 3.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Polysacc_deac_1 PF01522.21 KNZ75819.1 - 1.5e-14 54.0 0.1 4.4e-13 49.2 0.1 2.4 2 1 0 2 2 2 1 Polysaccharide deacetylase ADH_zinc_N PF00107.26 KNZ75820.1 - 2.5e-16 59.9 0.0 4.7e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ75820.1 - 2e-11 43.7 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KNZ75820.1 - 0.00048 21.2 0.0 0.00083 20.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ75820.1 - 0.049 13.5 0.0 0.22 11.4 0.0 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase NAC PF01849.18 KNZ75820.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 NAC domain GST_N_3 PF13417.6 KNZ75821.1 - 2.3e-19 69.5 0.0 4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KNZ75821.1 - 9.5e-18 64.3 0.0 1.8e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ75821.1 - 3.5e-11 43.2 0.0 7.8e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ75821.1 - 1.2e-10 41.4 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNZ75821.1 - 1.8e-05 24.6 0.0 3.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KNZ75821.1 - 0.036 14.8 0.0 0.061 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 KNZ75821.1 - 0.047 13.9 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KNZ75822.1 - 1.2e-17 64.0 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KNZ75822.1 - 1.5e-15 57.3 0.0 3.5e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ75822.1 - 2.6e-11 43.6 0.0 4.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ75822.1 - 4.4e-11 42.8 0.0 8.1e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNZ75822.1 - 5.2e-05 23.2 0.1 8.9e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain motB PF17613.2 KNZ75822.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Modifier of transcription GST_C_3 PF14497.6 KNZ75822.1 - 0.034 14.3 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SRP54 PF00448.22 KNZ75822.1 - 0.18 11.4 0.0 0.43 10.2 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain WD40 PF00400.32 KNZ75824.1 - 1.3e-142 459.4 61.4 8.6e-11 42.2 0.1 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75824.1 - 5.9e-47 157.9 10.1 0.022 15.0 0.0 14.1 1 1 13 14 14 14 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ75824.1 - 9e-24 82.9 16.0 0.078 12.9 0.2 13.8 14 0 0 14 14 14 6 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KNZ75824.1 - 5.8e-20 72.0 0.1 0.00095 19.1 0.0 5.5 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KNZ75824.1 - 1.4e-14 53.9 15.7 2.3 7.1 0.0 12.5 1 1 13 14 14 14 4 WD40 region of Ge1, enhancer of mRNA-decapping protein CHAP PF05257.16 KNZ75824.1 - 2.6e-12 47.1 32.2 1.9 9.1 0.1 11.9 1 1 8 11 11 11 3 CHAP domain Cytochrom_D1 PF02239.16 KNZ75824.1 - 4.4e-10 38.6 15.3 0.2 10.1 0.1 6.4 1 1 2 6 6 6 6 Cytochrome D1 heme domain PQQ PF01011.21 KNZ75824.1 - 1.7e-05 24.5 0.0 50 4.1 0.0 8.4 11 0 0 11 11 11 0 PQQ enzyme repeat WD40_like PF17005.5 KNZ75824.1 - 3.5e-05 23.3 0.2 47 3.2 0.0 6.5 2 2 9 11 11 11 0 WD40-like domain NACHT PF05729.12 KNZ75824.1 - 0.00054 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AcetylCoA_hyd_C PF13336.6 KNZ75824.1 - 0.0061 16.5 5.2 15 5.5 0.0 6.6 6 2 2 8 8 8 1 Acetyl-CoA hydrolase/transferase C-terminal domain Proteasome_A_N PF10584.9 KNZ75824.1 - 2.4 7.9 24.1 1.5e+02 2.2 0.0 11.1 13 0 0 13 13 13 0 Proteasome subunit A N-terminal signature PRKG1_interact PF15898.5 KNZ75825.1 - 0.004 18.0 3.6 0.0068 17.3 3.6 1.4 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain DUF4600 PF15372.6 KNZ75825.1 - 0.017 15.6 6.0 0.054 13.9 6.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) OmpH PF03938.14 KNZ75825.1 - 0.042 14.2 4.9 0.066 13.6 4.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HsdM_N PF12161.8 KNZ75825.1 - 0.064 13.9 6.0 0.27 11.9 3.2 2.1 1 1 1 2 2 2 0 HsdM N-terminal domain HTH_40 PF14493.6 KNZ75825.1 - 0.19 12.2 2.7 0.54 10.7 1.0 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain CHIP_TPR_N PF18391.1 KNZ75825.1 - 0.93 10.3 6.6 9.6 7.1 4.8 2.7 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain Methyltransf_2 PF00891.18 KNZ75826.1 - 8.6e-22 77.5 0.0 3.4e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KNZ75826.1 - 0.017 15.8 0.0 0.2 12.4 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ75826.1 - 0.054 14.2 0.0 0.18 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 KNZ75826.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain WD40 PF00400.32 KNZ75829.1 - 7.7e-165 529.8 74.1 4.2e-11 43.2 0.0 16.2 16 0 0 16 16 16 16 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75829.1 - 2.3e-54 181.6 9.6 0.0027 18.0 0.0 14.7 1 1 14 15 15 15 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ75829.1 - 5.9e-26 89.8 22.8 0.46 10.5 0.0 13.8 14 0 0 14 14 13 10 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KNZ75829.1 - 2.1e-20 73.4 0.1 0.00031 20.7 0.0 6.4 1 1 7 8 8 8 8 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KNZ75829.1 - 2.1e-13 50.3 0.8 0.95 8.7 0.0 8.4 4 3 5 10 10 10 5 WD40-like domain Ge1_WD40 PF16529.5 KNZ75829.1 - 9.8e-13 47.7 23.6 4.3 6.2 0.7 13.7 1 1 13 14 14 14 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Ret2_MD PF18528.1 KNZ75829.1 - 1.4e-12 47.8 0.1 24 5.4 0.0 11.7 5 4 9 14 14 14 0 RNA editing 3' terminal uridylyl transferase 2 middle domain HARP PF07443.13 KNZ75829.1 - 3.5e-12 45.8 0.0 3.5 7.3 0.0 9.8 11 0 0 11 11 11 1 HepA-related protein (HARP) Cytochrom_D1 PF02239.16 KNZ75829.1 - 1.5e-07 30.3 16.4 0.031 12.8 0.3 6.1 1 1 4 7 7 7 5 Cytochrome D1 heme domain Thioredox_DsbH PF03190.15 KNZ75829.1 - 0.0001 22.3 0.2 55 3.7 0.0 6.6 5 3 5 10 10 9 0 Protein of unknown function, DUF255 Frtz PF11768.8 KNZ75829.1 - 0.00026 19.4 0.0 13 3.9 0.0 6.0 3 2 6 9 9 9 0 WD repeat-containing and planar cell polarity effector protein Fritz AcetylCoA_hyd_C PF13336.6 KNZ75829.1 - 0.0011 18.9 6.0 42 4.0 0.0 7.0 4 3 2 8 8 8 0 Acetyl-CoA hydrolase/transferase C-terminal domain TPP_enzyme_M PF00205.22 KNZ75829.1 - 0.0021 17.8 0.0 19 5.0 0.0 4.7 3 2 2 5 5 5 0 Thiamine pyrophosphate enzyme, central domain DUF2173 PF09941.9 KNZ75829.1 - 0.012 15.9 0.0 64 3.9 0.0 5.8 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2173) PLD_C PF12357.8 KNZ75829.1 - 0.2 11.6 4.0 93 3.0 0.1 6.8 9 1 1 10 10 10 0 Phospholipase D C terminal DUF2096 PF09869.9 KNZ75830.1 - 0.0011 19.1 0.6 0.0017 18.4 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) PRKG1_interact PF15898.5 KNZ75830.1 - 0.024 15.5 2.3 0.058 14.3 2.3 1.6 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4600 PF15372.6 KNZ75830.1 - 1.9 9.0 7.1 1.7 9.1 4.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Methyltransf_2 PF00891.18 KNZ75831.1 - 1.6e-22 79.9 0.0 1e-19 70.7 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KNZ75831.1 - 0.0049 17.5 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ75831.1 - 0.016 15.9 0.0 0.089 13.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase_4 PF12146.8 KNZ75833.1 - 2.3e-11 43.4 0.0 4.8e-09 35.8 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ75833.1 - 1.3e-08 34.8 0.0 1.7e-07 31.1 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ75833.1 - 1.9e-05 25.4 0.0 4.2e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KNZ75833.1 - 0.00048 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KNZ75833.1 - 0.00052 19.9 0.0 0.0025 17.7 0.1 1.9 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KNZ75833.1 - 0.0025 17.3 0.0 0.0068 15.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KNZ75833.1 - 0.01 15.5 0.0 0.59 9.7 0.0 2.3 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 KNZ75833.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 KNZ75833.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF818 PF05677.12 KNZ75833.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 KNZ75833.1 - 0.15 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2526 PF10735.9 KNZ75833.1 - 0.16 12.2 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) FSH1 PF03959.13 KNZ75833.1 - 0.49 10.0 0.0 0.49 10.0 0.0 2.0 3 0 0 3 3 2 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 KNZ75833.1 - 0.61 10.2 3.6 2.6 8.1 0.1 2.8 2 1 1 3 3 3 0 Thioesterase domain LBR_tudor PF09465.10 KNZ75836.1 - 0.0084 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain Pkinase_fungal PF17667.1 KNZ75837.1 - 6.6e-29 100.9 0.0 1.5e-23 83.3 0.0 3.1 1 1 0 1 1 1 1 Fungal protein kinase Dioxygenase_C PF00775.21 KNZ75840.1 - 3.4e-08 33.1 0.1 2.4e-05 23.9 0.0 2.3 1 1 1 2 2 2 2 Dioxygenase NmrA PF05368.13 KNZ75842.1 - 1.5e-26 93.4 0.0 2.3e-26 92.8 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ75842.1 - 3.1e-06 27.2 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding PRA-CH PF01502.18 KNZ75842.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl-AMP cyclohydrolase NmrA PF05368.13 KNZ75843.1 - 7.3e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ75843.1 - 0.055 13.4 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KNZ75846.1 - 2.2e-26 92.9 0.0 3.4e-26 92.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ75846.1 - 1.8e-07 31.2 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding PI-PLC-X PF00388.19 KNZ75847.1 - 5e-05 22.9 0.0 7.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain His_Phos_2 PF00328.22 KNZ75848.1 - 8.9e-05 22.0 0.0 0.17 11.2 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Calc_CGRP_IAPP PF00214.19 KNZ75848.1 - 0.3 11.4 1.1 0.36 11.2 0.1 1.7 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family GMC_oxred_N PF00732.19 KNZ75849.1 - 2.2e-61 207.9 0.0 2.7e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ75849.1 - 6.1e-37 127.3 0.0 1.1e-36 126.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KNZ75849.1 - 0.00098 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ75849.1 - 0.0069 16.6 0.0 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ75849.1 - 0.0071 16.0 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ75849.1 - 0.05 12.7 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain FF PF01846.19 KNZ75849.1 - 0.052 13.7 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 FF domain TrkA_N PF02254.18 KNZ75849.1 - 0.075 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.14 KNZ75849.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ75849.1 - 0.16 11.2 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Glyco_transf_90 PF05686.12 KNZ75850.1 - 8.9e-21 74.2 0.0 2.9e-20 72.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF1422 PF07226.11 KNZ75850.1 - 0.052 13.6 0.2 0.09 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF3866 PF12982.7 KNZ75851.1 - 0.096 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Lactonase PF10282.9 KNZ75852.1 - 3.9e-34 118.4 0.0 4.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Sirohm_synth_M PF14824.6 KNZ75852.1 - 0.043 13.3 0.3 0.17 11.3 0.1 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Acetyltransf_1 PF00583.25 KNZ75853.1 - 5.9e-10 39.4 0.0 8.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ75853.1 - 6.2e-10 39.1 0.0 8.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ75853.1 - 5e-09 36.5 0.1 7.6e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ75853.1 - 0.016 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Transposase_mut PF00872.18 KNZ75853.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Acetyltransf_9 PF13527.7 KNZ75853.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Synaptobrevin PF00957.21 KNZ75854.1 - 1.9e-34 117.3 3.7 2.1e-34 117.1 3.7 1.0 1 0 0 1 1 1 1 Synaptobrevin Peptidase_M48_N PF16491.5 KNZ75854.1 - 0.014 15.3 0.3 0.018 14.9 0.3 1.1 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices TMEM117 PF15113.6 KNZ75854.1 - 0.067 12.1 0.6 0.087 11.7 0.6 1.0 1 0 0 1 1 1 0 TMEM117 protein family Shisa PF13908.6 KNZ75854.1 - 0.36 11.0 0.7 0.51 10.6 0.3 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF515 PF04415.12 KNZ75854.1 - 1.1 7.6 6.4 1.2 7.5 6.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) EPSP_synthase PF00275.20 KNZ75855.1 - 8.9e-121 403.5 0.2 1.6e-120 402.6 0.2 1.4 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KNZ75855.1 - 6.6e-99 330.3 0.0 3.1e-98 328.1 0.0 2.0 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KNZ75855.1 - 1.6e-53 182.3 0.0 3e-53 181.4 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KNZ75855.1 - 2.8e-31 108.8 0.0 1.7e-30 106.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KNZ75855.1 - 5.1e-26 90.8 0.0 8e-25 86.9 0.0 2.7 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KNZ75855.1 - 1.4e-07 31.5 0.1 8.9e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 KNZ75855.1 - 6.3e-07 29.5 0.0 2.4e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 KNZ75855.1 - 8.1e-06 25.5 0.2 3.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain AAA_33 PF13671.6 KNZ75855.1 - 0.034 14.3 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DegS PF05384.11 KNZ75855.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Sensor protein DegS Sacchrp_dh_NADP PF03435.18 KNZ75855.1 - 0.065 13.5 0.1 23 5.2 0.0 4.0 6 0 0 6 6 6 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 KNZ75856.1 - 7.4e-56 189.4 0.0 1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75856.1 - 6.6e-27 94.4 0.0 9.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ75856.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ75856.1 - 0.0072 15.7 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ75856.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RGS PF00615.19 KNZ75857.1 - 4.6e-09 36.6 2.0 7e-05 23.1 0.1 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain L51_S25_CI-B8 PF05047.16 KNZ75858.1 - 9.3e-14 51.1 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain EF-hand_1 PF00036.32 KNZ75860.1 - 1.7e-32 108.5 4.0 2.9e-10 38.9 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KNZ75860.1 - 5.2e-29 99.9 4.1 2e-13 50.0 0.2 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 KNZ75860.1 - 2.1e-27 95.3 1.1 4.8e-18 65.4 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KNZ75860.1 - 6.4e-21 72.9 2.5 1.1e-06 27.8 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 KNZ75860.1 - 1.2e-20 71.6 1.1 1.5e-09 37.0 0.0 3.5 3 1 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 KNZ75860.1 - 5.1e-10 39.5 0.2 0.00043 20.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 KNZ75860.1 - 5.8e-08 32.6 1.2 5.5e-05 23.1 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 KNZ75860.1 - 1.5e-05 25.3 0.1 0.00038 20.8 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 KNZ75860.1 - 1.9e-05 24.6 0.1 0.55 10.3 0.0 2.9 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KNZ75860.1 - 0.00012 22.1 0.2 0.00025 21.1 0.1 1.7 2 0 0 2 2 2 1 Ca2+ insensitive EF hand DUF1103 PF06513.11 KNZ75860.1 - 0.00042 20.0 1.9 0.00053 19.7 1.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) EF-hand_11 PF08976.11 KNZ75860.1 - 0.00046 21.0 0.0 0.0084 17.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 KNZ75860.1 - 0.0023 18.1 4.6 0.012 15.8 0.8 2.6 1 1 2 3 3 3 1 Dockerin type I domain Poly_export PF02563.16 KNZ75860.1 - 0.0093 16.2 0.0 0.47 10.7 0.0 2.3 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 KNZ75860.1 - 0.068 13.2 0.9 27 4.9 0.0 3.1 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF5580 PF17743.1 KNZ75860.1 - 0.076 11.5 0.0 0.085 11.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 KNZ75860.1 - 0.077 12.9 0.5 0.9 9.4 0.1 2.1 1 1 1 2 2 2 0 SurA N-terminal domain RuvA_C PF07499.13 KNZ75860.1 - 0.13 12.7 0.0 10 6.6 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 KNZ75860.1 - 0.14 12.3 0.1 0.23 11.6 0.1 1.5 1 1 0 1 1 1 0 Transcription factor MotA, activation domain DUF5132 PF17195.4 KNZ75860.1 - 0.36 10.9 1.2 20 5.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Glyco_hydro_92 PF07971.12 KNZ75861.1 - 1.2e-113 380.5 0.0 1.4e-113 380.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KNZ75861.1 - 6e-44 150.7 2.2 8.3e-44 150.3 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TFB6 PF17110.5 KNZ75862.1 - 0.25 11.1 2.1 0.31 10.8 2.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Acetyltransf_3 PF13302.7 KNZ75863.1 - 2.5e-15 57.4 0.0 4.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ75863.1 - 0.0025 18.0 0.0 0.0044 17.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KNZ75863.1 - 0.051 13.7 0.1 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_12 PF01670.16 KNZ75864.1 - 1.1e-33 117.0 9.5 1.3e-33 116.8 9.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 NAD_binding_4 PF07993.12 KNZ75865.1 - 1e-30 106.8 0.0 1.6e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ75865.1 - 1.5e-25 89.7 0.0 4.2e-25 88.2 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KNZ75865.1 - 1.5e-09 37.7 0.0 2.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KNZ75865.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 KNZ75865.1 - 0.073 13.4 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site KR PF08659.10 KNZ75865.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 KR domain Nucleo_P87 PF07267.11 KNZ75866.1 - 3.5 6.4 4.6 4.3 6.1 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1744 PF08490.12 KNZ75867.1 - 4.1e-124 414.2 0.0 5.6e-124 413.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KNZ75867.1 - 2e-75 254.0 0.1 3e-75 253.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 KNZ75867.1 - 1.5e-11 43.7 0.4 3.3e-05 22.8 0.0 3.6 3 1 0 3 3 3 3 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KNZ75867.1 - 8.2e-08 32.2 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KNZ75867.1 - 8e-05 22.7 0.0 0.00042 20.3 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily zf-C4pol PF14260.6 KNZ75867.1 - 0.24 11.9 5.7 0.94 10.0 5.7 2.1 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta MAP65_ASE1 PF03999.12 KNZ75868.1 - 8.7e-65 219.6 0.0 6.1e-62 210.2 0.0 2.2 2 0 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) ALIX_LYPXL_bnd PF13949.6 KNZ75868.1 - 0.0091 15.3 2.0 0.018 14.3 2.0 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MFS_1 PF07690.16 KNZ75869.1 - 2.3e-16 59.7 46.8 1.1e-10 41.0 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbX PF06596.11 KNZ75869.1 - 0.0088 16.0 0.4 0.0088 16.0 0.4 3.1 2 1 1 3 3 3 1 Photosystem II reaction centre X protein (PsbX) Acyl-CoA_dh_M PF02770.19 KNZ75870.1 - 0.042 14.1 0.0 0.41 10.9 0.0 2.3 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain DUF2019 PF09450.10 KNZ75870.1 - 0.059 13.3 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) Dimerisation PF08100.11 KNZ75870.1 - 0.095 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Acyl-CoA_dh_1 PF00441.24 KNZ75870.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Hydantoinase_B PF02538.14 KNZ75872.1 - 9.6e-210 697.4 0.8 1.1e-209 697.1 0.8 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase PX PF00787.24 KNZ75873.1 - 5e-13 49.0 0.0 4.7e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 PX domain Prenyltrans PF00432.21 KNZ75874.1 - 2.6e-53 177.4 7.5 5.3e-11 42.1 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KNZ75874.1 - 0.0039 16.3 0.0 0.01 14.9 0.0 1.7 1 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KNZ75874.1 - 0.018 14.2 0.0 3.7 6.5 0.0 3.4 2 1 2 4 4 4 0 Squalene-hopene cyclase N-terminal domain Acetyltransf_1 PF00583.25 KNZ75875.1 - 7.2e-14 52.0 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Mss4 PF04421.13 KNZ75875.1 - 1.8e-13 50.5 0.0 2.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_10 PF13673.7 KNZ75875.1 - 2.3e-08 34.0 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ75875.1 - 2.5e-08 34.2 0.0 5.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KNZ75875.1 - 6.6e-07 29.5 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ75875.1 - 5.9e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_13 PF13880.6 KNZ75875.1 - 0.00055 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 KNZ75875.1 - 0.0079 15.7 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 KNZ75875.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Glyco_hydro_88 PF07470.13 KNZ75876.1 - 3.5e-61 207.2 3.3 4.3e-61 206.9 3.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KNZ75876.1 - 0.039 12.5 0.1 0.077 11.5 0.1 1.4 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 KNZ75877.1 - 6.7e-66 222.7 1.1 8.1e-66 222.4 1.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KNZ75877.1 - 0.038 13.5 8.0 3.1 7.2 0.5 3.2 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 KNZ75877.1 - 0.092 11.2 0.1 0.39 9.2 0.1 1.7 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 KNZ75878.1 - 4.1e-64 216.8 0.5 5.5e-64 216.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 KNZ75878.1 - 0.1 12.1 9.1 3.3 7.1 1.8 3.3 3 1 0 3 3 3 0 Glycosyl hydrolase family 76 Tfb5 PF06331.12 KNZ75879.1 - 3.4e-13 49.3 0.5 4.1e-13 49.1 0.5 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Rib_5-P_isom_A PF06026.14 KNZ75880.1 - 1.3e-60 203.9 0.0 1.7e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 KNZ75880.1 - 0.032 14.2 0.1 0.26 11.2 0.0 2.0 1 1 1 2 2 2 0 DeoR C terminal sensor domain BCS1_N PF08740.11 KNZ75881.1 - 9e-35 120.3 0.6 9e-35 120.3 0.6 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KNZ75881.1 - 6.9e-13 49.2 0.0 1.4e-11 45.0 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ75881.1 - 0.0078 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF3681 PF12442.8 KNZ75882.1 - 0.041 14.3 0.4 0.24 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Aconitase PF00330.20 KNZ75883.1 - 2.5e-152 508.1 0.0 3.2e-152 507.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KNZ75883.1 - 4.5e-43 146.7 0.0 9.1e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PIF1 PF05970.14 KNZ75885.1 - 6.2e-07 28.9 3.9 1.7e-05 24.2 3.9 2.9 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 KNZ75886.1 - 0.00045 20.5 0.0 0.0005 20.3 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus SGL PF08450.12 KNZ75888.1 - 1.7e-12 47.5 0.6 4e-12 46.3 0.6 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 KNZ75888.1 - 0.016 15.3 0.3 0.11 12.7 0.1 2.5 2 1 0 2 2 2 0 Arylesterase Chlorovi_GP_rpt PF06598.11 KNZ75888.1 - 0.061 13.4 1.2 0.1 12.7 0.1 2.0 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat Aida_N PF08910.10 KNZ75890.1 - 0.077 13.4 0.1 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Aida N-terminus Cyt-b5 PF00173.28 KNZ75891.1 - 2e-12 47.1 0.0 4.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 KNZ75891.1 - 6.6e-08 32.7 8.5 6.6e-08 32.7 8.5 2.2 1 1 1 2 2 2 1 Fatty acid desaturase Na_H_antiport_2 PF13726.6 KNZ75892.1 - 2.3 8.4 5.2 1e+02 3.1 0.0 3.7 3 0 0 3 3 3 0 Na+-H+ antiporter family TACI-CRD2 PF09305.10 KNZ75892.1 - 3.5 7.7 8.9 16 5.6 4.6 3.9 4 0 0 4 4 4 0 TACI, cysteine-rich domain Stig1 PF04885.13 KNZ75893.1 - 0.018 15.5 0.3 0.018 15.5 0.3 1.9 1 1 1 2 2 2 0 Stigma-specific protein, Stig1 HMG_box PF00505.19 KNZ75895.1 - 0.028 14.8 1.0 0.028 14.8 1.0 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box DUF4816 PF16086.5 KNZ75895.1 - 5.1 7.1 19.6 3.3 7.7 15.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4816) QRPTase_C PF01729.19 KNZ75896.1 - 0.19 11.5 0.6 0.42 10.4 0.4 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain RVP_2 PF08284.11 KNZ75897.1 - 0.0024 17.7 0.1 0.0026 17.5 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease PIF1 PF05970.14 KNZ75898.1 - 5.4e-47 160.7 0.8 5.8e-46 157.3 0.8 2.0 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ75898.1 - 6.3e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ75898.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KNZ75898.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MitMem_reg PF13012.6 KNZ75898.1 - 0.036 14.5 0.0 0.087 13.3 0.0 1.7 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function RNA_helicase PF00910.22 KNZ75898.1 - 0.042 14.2 0.2 0.25 11.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF2791 PF10923.8 KNZ75898.1 - 0.064 12.1 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.6 KNZ75898.1 - 0.09 13.0 0.2 0.49 10.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KNZ75898.1 - 0.13 12.7 0.5 2.3 8.7 0.1 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 KNZ75898.1 - 0.19 11.4 0.1 0.51 10.0 0.1 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helitron_like_N PF14214.6 KNZ75899.1 - 8.3e-11 42.4 0.0 8.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Pkinase PF00069.25 KNZ75900.1 - 2.6e-26 92.6 0.0 4.5e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ75900.1 - 1e-25 90.5 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RT_RNaseH PF17917.1 KNZ75900.1 - 7.8e-05 22.9 0.0 0.00021 21.6 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ75900.1 - 0.00052 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Kdo PF06293.14 KNZ75900.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Helitron_like_N PF14214.6 KNZ75901.1 - 1.2e-15 58.2 0.0 1.5e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ75901.1 - 0.054 13.4 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 Inovirus Gp2 FF PF01846.19 KNZ75902.1 - 0.011 15.8 0.0 0.7 10.1 0.0 2.3 2 0 0 2 2 2 0 FF domain PIF1 PF05970.14 KNZ75903.1 - 1e-109 367.0 0.0 1.2e-109 366.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ75903.1 - 2e-08 34.2 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ75903.1 - 0.0054 17.1 0.0 0.0094 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain 4HPAD_g_N PF18671.1 KNZ75903.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Viral_helicase1 PF01443.18 KNZ75903.1 - 0.065 13.0 0.2 0.14 11.9 0.2 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ75903.1 - 0.076 13.0 0.0 0.26 11.3 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.14 KNZ75904.1 - 0.0059 14.6 0.0 0.0067 14.4 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ75904.1 - 0.057 13.2 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain SGL PF08450.12 KNZ75905.1 - 6.1e-27 94.8 0.1 1e-26 94.1 0.1 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 KNZ75905.1 - 0.00051 20.1 0.0 0.0063 16.6 0.0 2.7 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 KNZ75905.1 - 0.025 14.8 0.5 0.17 12.1 0.0 2.7 3 1 0 3 3 3 0 Arylesterase FA_desaturase PF00487.24 KNZ75906.1 - 0.028 14.3 4.1 0.039 13.8 4.1 1.3 1 1 0 1 1 1 0 Fatty acid desaturase LapA_dom PF06305.11 KNZ75906.1 - 0.066 13.0 7.1 2 8.3 1.5 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain SASP PF00269.20 KNZ75906.1 - 0.21 11.6 1.1 0.42 10.7 1.1 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type DUF2304 PF10066.9 KNZ75906.1 - 2.7 8.3 6.0 3.9 7.8 0.1 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Tetraspanin PF00335.20 KNZ75906.1 - 5.9 6.5 10.0 8.4 6.0 8.8 1.6 1 1 0 1 1 1 0 Tetraspanin family SPT_ssu-like PF11779.8 KNZ75907.1 - 1.1e-07 31.3 6.6 1.6e-07 30.8 6.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like SPT_ssu-like PF11779.8 KNZ75908.1 - 5.9e-13 48.2 4.2 1.1e-12 47.4 4.2 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Ferric_reduct PF01794.19 KNZ75909.1 - 1.1e-17 64.4 10.1 2e-17 63.5 10.1 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KNZ75909.1 - 1.1e-11 44.8 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KNZ75909.1 - 2.4e-10 40.7 0.0 6e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain DUF2069 PF09842.9 KNZ75909.1 - 0.0037 17.5 1.1 0.0037 17.5 1.1 2.7 3 0 0 3 3 3 1 Predicted membrane protein (DUF2069) GREB1 PF15782.5 KNZ75909.1 - 0.12 9.4 0.1 0.16 9.0 0.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pyr_redox_2 PF07992.14 KNZ75910.1 - 1.2e-52 179.0 0.0 1.5e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ75910.1 - 1.1e-10 41.8 0.0 8.3e-09 35.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ75910.1 - 0.00086 18.6 0.0 0.14 11.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KNZ75910.1 - 0.019 15.4 1.0 0.17 12.3 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.14 KNZ75910.1 - 0.82 8.3 2.7 1.4 7.5 0.0 2.4 2 1 1 3 3 3 0 HI0933-like protein GCP_N_terminal PF17681.1 KNZ75911.1 - 2.5e-63 214.5 0.0 4.8e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KNZ75911.1 - 1.3e-37 129.9 9.9 6.8e-27 94.7 1.8 2.8 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal Peptidase_C2 PF00648.21 KNZ75912.1 - 3.5e-66 223.2 0.1 2.3e-65 220.6 0.1 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease MCC-bdg_PDZ PF10506.9 KNZ75912.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Dna2 PF08696.11 KNZ75913.1 - 5.7e-59 199.3 0.2 9.7e-59 198.6 0.2 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KNZ75913.1 - 4.1e-53 180.0 0.1 6.5e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ75913.1 - 7e-32 111.2 0.1 3.9e-16 59.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 KNZ75913.1 - 4.6e-16 59.1 0.0 9.6e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ75913.1 - 3.7e-11 43.5 0.3 1.8e-10 41.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KNZ75913.1 - 1.6e-07 31.3 1.3 0.24 11.1 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.7 KNZ75913.1 - 1.7e-06 28.2 0.0 4.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.14 KNZ75913.1 - 1.4e-05 25.0 0.0 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 KNZ75913.1 - 0.00044 20.7 0.1 0.0092 16.4 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain Cas_Cas4 PF01930.17 KNZ75913.1 - 0.0006 20.0 1.1 0.0063 16.6 0.5 2.8 2 1 0 2 2 2 1 Domain of unknown function DUF83 PIF1 PF05970.14 KNZ75913.1 - 0.0033 16.7 0.0 0.18 10.9 0.1 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.21 KNZ75913.1 - 0.01 15.4 0.2 0.019 14.5 0.2 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Rad17 PF03215.15 KNZ75913.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 KNZ75913.1 - 0.023 14.4 0.8 0.041 13.5 0.8 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KNZ75913.1 - 0.023 14.9 0.6 0.72 10.1 0.2 3.1 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KNZ75913.1 - 0.029 13.4 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KNZ75913.1 - 0.042 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KNZ75913.1 - 0.044 13.7 0.1 1.5 8.7 0.0 2.9 2 1 1 3 3 3 0 RsgA GTPase AAA PF00004.29 KNZ75913.1 - 0.045 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KNZ75913.1 - 0.045 12.7 0.1 0.12 11.4 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 KNZ75913.1 - 0.052 13.5 0.7 0.15 12.0 0.7 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 KNZ75913.1 - 0.054 13.0 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KNZ75913.1 - 0.062 13.5 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KNZ75913.1 - 0.078 12.7 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KNZ75913.1 - 0.1 12.0 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KNZ75913.1 - 0.1 12.7 0.2 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CbiA PF01656.23 KNZ75913.1 - 0.41 10.7 1.5 1 9.5 1.5 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 KNZ75913.1 - 0.71 9.8 2.4 1.1 9.1 0.3 2.2 2 0 0 2 2 2 0 NTPase ArsA_ATPase PF02374.15 KNZ75913.1 - 0.86 8.7 3.3 7 5.7 0.9 2.5 2 1 0 2 2 2 0 Anion-transporting ATPase CUE PF02845.16 KNZ75915.1 - 4.8e-10 38.9 0.0 7.6e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain stn_TNFRSF12A PF12191.8 KNZ75916.1 - 0.0025 18.0 1.6 0.036 14.3 0.2 2.4 1 1 1 2 2 2 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Tfb4 PF03850.14 KNZ75916.1 - 0.012 15.1 0.6 0.021 14.4 0.1 1.6 2 0 0 2 2 2 0 Transcription factor Tfb4 EphA2_TM PF14575.6 KNZ75916.1 - 0.028 15.3 0.3 0.062 14.2 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SNARE PF05739.19 KNZ75917.1 - 0.00013 21.9 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 SNARE domain Sec20 PF03908.13 KNZ75917.1 - 0.12 12.4 0.1 7 6.6 0.0 2.6 2 1 0 2 2 2 0 Sec20 GATase PF00117.28 KNZ75918.1 - 5.5e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Ribosomal_60s PF00428.19 KNZ75919.1 - 0.53 10.9 2.7 5.7 7.6 0.1 2.6 2 1 0 2 2 2 0 60s Acidic ribosomal protein SPX PF03105.19 KNZ75919.1 - 2.8 7.8 14.1 3.3 7.5 14.1 1.1 1 0 0 1 1 1 0 SPX domain APH PF01636.23 KNZ75920.1 - 8.1e-07 29.2 0.0 1.6e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ75920.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 KNZ75921.1 - 3.2e-42 144.8 0.0 8.1e-25 87.4 0.1 2.3 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KNZ75921.1 - 8e-05 22.7 0.1 0.00072 19.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ75921.1 - 0.0032 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PIF1 PF05970.14 KNZ75922.1 - 2.5e-53 181.5 0.2 2.8e-53 181.4 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ75922.1 - 2e-05 24.4 0.0 2.6e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ75922.1 - 0.0032 17.2 0.2 0.011 15.4 0.2 1.8 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KNZ75922.1 - 0.019 15.3 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KNZ75922.1 - 0.02 15.3 0.1 0.059 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ75922.1 - 0.051 14.0 0.1 0.22 11.9 0.1 1.9 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.15 KNZ75922.1 - 0.083 12.9 0.0 0.31 11.0 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KNZ75922.1 - 0.14 11.8 0.1 0.13 11.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 KNZ75923.1 - 0.038 14.2 0.0 0.041 14.1 0.0 1.1 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus Integrase_H2C2 PF17921.1 KNZ75924.1 - 2.4e-10 40.4 3.6 2.4e-10 40.4 3.6 1.9 3 0 0 3 3 3 1 Integrase zinc binding domain RT_RNaseH_2 PF17919.1 KNZ75925.1 - 1.8e-06 27.9 0.0 2.1e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ75925.1 - 3.4e-05 24.1 0.0 3.7e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase TP2 PF01254.18 KNZ75925.1 - 0.99 10.0 5.5 1.3 9.7 5.5 1.1 1 0 0 1 1 1 0 Nuclear transition protein 2 gag-asp_proteas PF13975.6 KNZ75926.1 - 0.05 14.2 0.0 0.06 13.9 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Vps26 PF03643.15 KNZ75928.1 - 3e-42 144.6 0.1 2.6e-34 118.5 0.1 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 PCNA_N PF00705.18 KNZ75930.1 - 4.4e-43 146.0 6.5 7e-43 145.4 6.5 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KNZ75930.1 - 9.9e-28 96.9 0.2 1.7e-13 50.8 0.0 2.7 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KNZ75930.1 - 0.0011 18.5 0.4 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 Rad9 RR_TM4-6 PF06459.12 KNZ75930.1 - 0.0034 17.3 0.2 0.0047 16.8 0.2 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Hus1 PF04005.12 KNZ75930.1 - 0.16 11.1 1.1 3.5 6.7 0.4 2.5 2 1 1 3 3 3 0 Hus1-like protein DUF2992 PF11208.8 KNZ75930.1 - 0.2 11.9 2.9 0.34 11.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) CDC45 PF02724.14 KNZ75930.1 - 0.35 9.1 2.8 0.44 8.8 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein NMD3 PF04981.13 KNZ75931.1 - 4.2e-07 29.7 2.8 8e-07 28.8 0.0 2.1 1 1 1 2 2 2 2 NMD3 family Glyco_hyd_65N_2 PF14498.6 KNZ75932.1 - 8e-34 117.5 0.2 1.1e-33 117.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Paf67 PF10255.9 KNZ75933.1 - 4.3e-162 539.7 0.0 1.3e-161 538.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 ANAPC3 PF12895.7 KNZ75933.1 - 0.022 15.0 0.1 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KNZ75933.1 - 0.1 12.7 0.0 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_trans_2_3 PF13632.6 KNZ75935.1 - 1.7e-56 191.3 2.2 1.7e-56 191.3 2.2 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KNZ75935.1 - 5.4e-06 26.5 0.1 9.3e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KNZ75935.1 - 6.2e-05 22.9 0.0 0.00025 20.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KNZ75935.1 - 0.0072 15.8 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 KNZ75936.1 - 3.6e-17 62.4 0.1 7.4e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 vATP-synt_E PF01991.18 KNZ75937.1 - 9.7e-57 191.6 8.7 1.1e-56 191.4 8.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 KNZ75937.1 - 0.28 11.6 4.4 3.2 8.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Kinesin PF00225.23 KNZ75938.1 - 3.4e-92 308.9 0.0 1.6e-51 175.3 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 KNZ75938.1 - 2.1e-21 76.5 0.0 5.3e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HR1 PF02185.16 KNZ75938.1 - 0.16 12.1 6.4 0.34 11.1 0.1 3.5 2 1 1 3 3 3 0 Hr1 repeat Pox_A_type_inc PF04508.12 KNZ75938.1 - 0.23 11.4 7.1 0.054 13.4 2.7 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Vfa1 PF08432.10 KNZ75938.1 - 7.3 6.9 15.5 0.072 13.4 1.2 2.3 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ribosomal_L14 PF00238.19 KNZ75939.1 - 1.3e-23 83.4 0.1 1.4e-23 83.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SporV_AA PF12164.8 KNZ75941.1 - 0.083 13.3 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AA POT1PC PF16686.5 KNZ75943.1 - 0.03 14.2 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein CMAS PF02353.20 KNZ75947.1 - 2.1e-64 217.4 0.1 2.6e-64 217.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KNZ75947.1 - 1.1e-12 48.4 0.0 1.8e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ75947.1 - 1.7e-11 44.7 0.0 6e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ75947.1 - 1.9e-09 37.6 0.0 4.2e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ75947.1 - 5.7e-07 30.2 0.0 1.3e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KNZ75947.1 - 2.3e-05 24.0 0.0 6.3e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 MTS PF05175.14 KNZ75947.1 - 0.004 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 KNZ75947.1 - 0.0044 16.8 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KNZ75947.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TMEM208_SND2 PF05620.11 KNZ75947.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 MetW PF07021.12 KNZ75947.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Metallophos_2 PF12850.7 KNZ75948.1 - 6.1e-17 62.3 0.4 1.1e-16 61.5 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CMAS PF02353.20 KNZ75948.1 - 6.6e-12 45.3 0.0 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Metallophos PF00149.28 KNZ75948.1 - 1.1e-05 26.1 0.9 0.058 13.9 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase DOT1 PF08123.13 KNZ75948.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KNZ75948.1 - 0.0046 16.5 0.0 0.0088 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KNZ75948.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KNZ75948.1 - 0.12 12.2 0.2 0.38 10.6 0.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ75948.1 - 0.23 12.2 0.3 0.64 10.8 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain S4 PF01479.25 KNZ75949.1 - 2.2e-06 27.3 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 KNZ75949.1 - 0.0028 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain PFK PF00365.20 KNZ75950.1 - 1.1e-184 612.3 1.5 3.2e-103 345.0 1.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.19 KNZ75950.1 - 0.056 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif CMAS PF02353.20 KNZ75952.1 - 5.3e-58 196.5 0.0 7e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KNZ75952.1 - 5.1e-07 30.3 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ75952.1 - 3.1e-05 24.5 0.0 6.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KNZ75952.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 MTS PF05175.14 KNZ75952.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SAC3 PF12209.8 KNZ75952.1 - 0.14 12.4 0.1 0.35 11.1 0.0 1.7 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain Methyltransf_12 PF08242.12 KNZ75952.1 - 0.16 12.7 0.0 0.46 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Abhydrolase_6 PF12697.7 KNZ75953.1 - 2e-10 41.7 0.1 2.4e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.22 KNZ75954.1 - 1.1e-63 215.6 0.0 1.2e-63 215.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NMO PF03060.15 KNZ75955.1 - 1.9e-30 106.4 3.3 1.3e-14 54.4 0.7 3.4 3 1 0 3 3 3 3 Nitronate monooxygenase Lipase_GDSL PF00657.22 KNZ75956.1 - 6.3e-05 23.0 0.0 7.1e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.22 KNZ75957.1 - 4.4e-13 48.8 0.0 6.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PCI PF01399.27 KNZ75958.1 - 1.4e-10 41.6 0.2 1.5e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain Med16 PF11635.8 KNZ75958.1 - 0.067 11.1 0.4 0.17 9.8 0.0 1.7 2 0 0 2 2 2 0 Mediator complex subunit 16 Ribosomal_S8 PF00410.19 KNZ75959.1 - 3.1e-10 40.1 0.0 1.3e-09 38.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 DUF5437 PF17505.2 KNZ75959.1 - 0.094 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5437) VHS PF00790.19 KNZ75960.1 - 2.4e-36 124.7 0.0 1e-35 122.6 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KNZ75960.1 - 1.8e-19 69.8 0.2 2.2e-18 66.3 0.0 2.7 3 0 0 3 3 3 1 GAT domain GGA_N-GAT PF18308.1 KNZ75960.1 - 0.022 14.4 0.1 0.056 13.1 0.1 1.7 1 0 0 1 1 1 0 GGA N-GAT domain DUF382 PF04037.13 KNZ75961.1 - 6.5e-56 187.9 0.4 2.4e-55 186.1 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 KNZ75961.1 - 1.6e-17 63.1 3.8 3.3e-17 62.1 3.8 1.6 1 0 0 1 1 1 1 PSP DBR1 PF05011.13 KNZ75962.1 - 8.5e-39 133.2 0.0 2.4e-38 131.7 0.0 1.7 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KNZ75962.1 - 1.7e-07 32.0 2.6 2.3e-07 31.5 2.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KNZ75962.1 - 0.0021 17.5 0.0 0.0099 15.2 0.0 2.1 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily WH1 PF00568.23 KNZ75963.1 - 4.9e-24 84.4 0.0 6.6e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KNZ75963.1 - 1.5e-05 25.3 0.0 3.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain DUF2076 PF09849.9 KNZ75963.1 - 0.073 13.1 0.5 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_B PF00136.21 KNZ75964.1 - 1.6e-114 383.1 0.0 4.4e-114 381.7 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KNZ75964.1 - 9.5e-58 195.0 0.6 1.7e-57 194.1 0.6 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KNZ75964.1 - 2.7e-25 89.2 0.0 6e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KNZ75964.1 - 1.7e-16 60.0 6.2 1.7e-16 60.0 6.2 2.0 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KNZ75964.1 - 0.064 12.1 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral PDH PF02153.17 KNZ75965.1 - 4.7e-12 45.4 0.0 7.2e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KNZ75965.1 - 7.9e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KNZ75965.1 - 7.3e-05 23.3 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KNZ75965.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 KNZ75965.1 - 0.12 12.0 0.1 0.34 10.5 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KNZ75965.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ETF_QO PF05187.13 KNZ75966.1 - 1.6e-13 50.7 0.1 2.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 KNZ75966.1 - 1.5e-07 31.3 0.3 2.1e-06 27.6 0.4 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ75966.1 - 3.9e-07 30.2 0.0 1.3e-06 28.5 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KNZ75966.1 - 1.4e-05 24.5 0.0 0.0048 16.2 0.1 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 KNZ75966.1 - 1.9e-05 24.0 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ75966.1 - 3.9e-05 22.9 0.7 0.00037 19.7 1.3 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 KNZ75966.1 - 0.00014 21.3 0.1 0.00022 20.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 KNZ75966.1 - 0.0002 21.4 0.4 0.00043 20.3 0.4 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KNZ75966.1 - 0.00045 19.0 0.5 0.00081 18.2 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KNZ75966.1 - 0.00051 19.4 0.3 0.00081 18.7 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ75966.1 - 0.0062 15.6 0.3 0.015 14.3 0.3 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 KNZ75966.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KNZ75966.1 - 0.088 11.6 0.2 0.15 10.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KNZ75966.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF570 PF04489.13 KNZ75967.1 - 0.05 12.2 0.1 0.075 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Asp_protease_2 PF13650.6 KNZ75968.1 - 0.11 13.1 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Cnn_1N PF07989.11 KNZ75969.1 - 9.1e-23 80.2 9.9 9.1e-23 80.2 9.9 11.4 5 2 5 10 10 10 1 Centrosomin N-terminal motif 1 DHR10 PF18595.1 KNZ75969.1 - 0.0016 18.5 20.0 0.0016 18.5 20.0 12.0 2 2 7 11 11 11 2 Designed helical repeat protein 10 domain HrpB7 PF09486.10 KNZ75969.1 - 0.0027 18.1 14.3 0.0027 18.1 14.3 8.9 2 2 6 8 8 8 1 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 KNZ75969.1 - 0.0041 17.7 1.6 0.0041 17.7 1.6 11.1 4 2 7 12 12 12 3 Clathrin-binding domain of Huntingtin-interacting protein 1 Sh_2 PF17512.2 KNZ75969.1 - 0.25 11.1 2.0 0.31 10.8 0.2 2.1 2 1 1 3 3 3 0 Metapneumovirus Small hydrophobic protein Rsa3 PF14615.6 KNZ75969.1 - 1.2 8.7 4.9 0.34 10.5 0.6 2.4 2 0 0 2 2 2 0 Ribosome-assembly protein 3 TFIIB PF00382.19 KNZ75971.1 - 2.1e-34 117.4 0.3 2.9e-18 65.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KNZ75971.1 - 1.2e-27 96.2 4.1 5.2e-27 94.1 1.9 2.4 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 KNZ75971.1 - 1.4e-07 30.9 2.6 3.3e-07 29.7 2.6 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding rve PF00665.26 KNZ75971.1 - 2.9e-06 27.5 0.1 7e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Cyclin_N PF00134.23 KNZ75971.1 - 0.00021 21.0 0.3 0.18 11.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain DZR PF12773.7 KNZ75971.1 - 0.022 14.8 0.3 0.053 13.5 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RRN7 PF11781.8 KNZ75971.1 - 0.1 12.3 3.3 0.2 11.4 3.3 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4145 PF13643.6 KNZ75971.1 - 0.12 12.5 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) polyprenyl_synt PF00348.17 KNZ75972.1 - 6.3e-61 205.7 0.0 3.3e-56 190.2 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Retrotran_gag_2 PF14223.6 KNZ75973.1 - 3.2e-08 33.3 0.1 4.4e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Herpes_V23 PF01802.17 KNZ75973.1 - 0.027 13.9 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Pex19 PF04614.12 KNZ75974.1 - 2.4e-58 197.8 4.6 3.1e-58 197.4 4.6 1.2 1 0 0 1 1 1 1 Pex19 protein family AAA_32 PF13654.6 KNZ75974.1 - 0.0097 14.7 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain FliE PF02049.18 KNZ75974.1 - 0.015 15.5 1.2 0.042 14.0 0.6 2.1 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE Merozoite_SPAM PF07133.11 KNZ75974.1 - 0.028 14.4 1.1 0.037 14.0 1.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop16 PF09420.10 KNZ75974.1 - 0.041 13.9 0.2 0.057 13.4 0.2 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 FlaC_arch PF05377.11 KNZ75975.1 - 0.055 13.9 0.4 0.099 13.1 0.4 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) LOH1CR12 PF10158.9 KNZ75975.1 - 0.07 13.1 0.1 0.079 13.0 0.1 1.1 1 0 0 1 1 1 0 Tumour suppressor protein EMP24_GP25L PF01105.24 KNZ75975.1 - 0.12 12.4 0.6 0.12 12.2 0.6 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD polyprenyl_synt PF00348.17 KNZ75976.1 - 8.3e-32 110.2 0.0 7.7e-31 107.1 0.0 2.0 1 1 0 1 1 1 1 Polyprenyl synthetase BING4CT PF08149.11 KNZ75977.1 - 2.8e-36 123.2 0.0 4.6e-35 119.3 0.0 2.7 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 KNZ75977.1 - 9.5e-06 26.3 2.3 0.00019 22.1 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ75977.1 - 0.006 16.9 0.0 2.7 8.4 0.0 3.8 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KNZ75977.1 - 0.031 12.8 0.1 0.25 9.8 0.0 2.1 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF1202 PF06717.11 KNZ75977.1 - 0.15 11.4 3.0 0.27 10.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Exo_endo_phos_2 PF14529.6 KNZ75979.1 - 0.0046 16.8 0.1 0.0091 15.8 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KNZ75980.1 - 0.013 15.1 0.0 0.013 15.1 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 KNZ75981.1 - 0.00011 22.4 0.8 0.0022 18.2 0.8 2.4 1 1 0 1 1 1 1 RNase H Orai-1 PF07856.12 KNZ75983.1 - 9 5.9 10.1 2.9 7.6 1.7 2.3 2 0 0 2 2 2 0 Mediator of CRAC channel activity CorA PF01544.18 KNZ75984.1 - 9.7e-12 44.8 0.6 2.5e-11 43.5 0.2 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Pre-SET PF05033.16 KNZ75986.1 - 3.6e-18 66.2 1.0 3.6e-18 66.2 1.0 1.8 2 0 0 2 2 2 1 Pre-SET motif SET PF00856.28 KNZ75986.1 - 1.4e-16 61.4 0.1 5.3e-16 59.5 0.1 2.1 1 1 0 1 1 1 1 SET domain UQ_con PF00179.26 KNZ75987.1 - 1e-40 138.6 0.0 1.4e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNZ75987.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KNZ75987.1 - 0.053 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyco_hydro_35 PF01301.19 KNZ75988.1 - 4.6e-80 269.6 0.4 7.1e-80 269.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KNZ75988.1 - 9.5e-53 177.6 4.3 2.1e-32 112.0 0.0 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KNZ75988.1 - 1.6e-24 86.7 4.8 2.8e-24 85.9 4.8 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KNZ75988.1 - 5.4e-14 51.5 0.1 1.2e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 ORC5_C PF14630.6 KNZ75989.1 - 1.3e-58 198.8 0.0 1.6e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus YycC PF14174.6 KNZ75989.1 - 0.0095 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 YycC-like protein CBM_1 PF00734.18 KNZ75990.1 - 1.3e-10 41.1 9.2 1.3e-10 41.1 9.2 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.12 KNZ75990.1 - 0.06 12.0 0.1 0.15 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) MGC-24 PF05283.11 KNZ75990.1 - 6.3 7.3 11.7 2 8.8 8.5 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MSP1_C PF07462.11 KNZ75990.1 - 7.3 5.2 5.6 14 4.2 5.6 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ParA PF10609.9 KNZ75991.1 - 1.7e-74 250.4 0.0 2.2e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KNZ75991.1 - 5.1e-12 46.0 0.0 8.9e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KNZ75991.1 - 5.4e-08 32.9 0.5 2.7e-07 30.7 0.4 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KNZ75991.1 - 0.00047 19.4 0.5 0.0048 16.1 0.3 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 KNZ75991.1 - 0.0021 17.4 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KNZ75991.1 - 0.0042 16.7 0.0 0.0069 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KNZ75991.1 - 0.0098 15.7 0.2 0.054 13.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain F-box-like PF12937.7 KNZ75992.1 - 0.00027 20.8 1.3 0.001 18.9 1.3 2.1 1 1 0 1 1 1 1 F-box-like REV PF00424.18 KNZ75993.1 - 0.042 13.9 0.4 0.093 12.8 0.4 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) F-box-like PF12937.7 KNZ75994.1 - 4.8e-06 26.4 0.7 1.7e-05 24.6 0.3 2.2 2 1 0 2 2 2 1 F-box-like p450 PF00067.22 KNZ75995.1 - 6.4e-66 223.0 0.0 1e-65 222.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2258 PF10015.9 KNZ75996.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) Nrap_D4 PF17405.2 KNZ75997.1 - 3.9e-63 212.7 0.0 8.6e-63 211.5 0.0 1.6 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 KNZ75997.1 - 9.4e-44 149.3 0.0 1.6e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D2 PF17403.2 KNZ75997.1 - 1.3e-43 148.4 0.0 3e-42 143.9 0.0 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 KNZ75997.1 - 4.5e-40 137.1 0.0 1.3e-37 129.0 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 KNZ75997.1 - 4.9e-39 133.8 0.8 7.5e-39 133.2 0.8 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KNZ75997.1 - 9.8e-34 116.5 0.0 1.9e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 LysM PF01476.20 KNZ75998.1 - 4.9e-13 48.9 0.3 1e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 LysM domain ThiF PF00899.21 KNZ76000.1 - 7.3e-70 235.1 0.0 1e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 KNZ76000.1 - 2.6e-17 63.6 0.1 5e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 KNZ76000.1 - 7.7e-07 29.6 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 KNZ76000.1 - 0.012 16.0 0.0 0.051 14.0 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 KNZ76000.1 - 0.2 10.8 0.1 1.6 7.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Herpes_Helicase PF02689.14 KNZ76004.1 - 2.2e-05 22.6 0.1 2.3e-05 22.6 0.1 1.0 1 0 0 1 1 1 1 Helicase MIF PF01187.18 KNZ76006.1 - 3.7e-14 53.0 0.0 4.6e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) TauD PF02668.16 KNZ76007.1 - 8.3e-29 101.2 0.0 1.1e-28 100.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KNZ76007.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 CsiD Rpp20 PF12328.8 KNZ76008.1 - 4.2e-06 26.8 0.2 5.2e-05 23.2 0.1 2.1 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P eRF1_2 PF03464.15 KNZ76009.1 - 1.3e-47 161.5 0.1 2.4e-47 160.6 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KNZ76009.1 - 6.2e-39 133.0 0.4 1.3e-38 132.0 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KNZ76009.1 - 1.1e-19 70.8 0.0 2e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 KNZ76009.1 - 6.5e-10 39.4 0.1 1e-09 38.8 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 KNZ76009.1 - 9.2e-09 35.7 0.0 1.5e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF3600 PF12207.8 KNZ76009.1 - 0.081 12.9 0.2 0.19 11.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) DUF3895 PF13034.6 KNZ76011.1 - 0.052 13.5 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) gag-asp_proteas PF13975.6 KNZ76012.1 - 9.3e-05 22.9 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76012.1 - 0.0016 19.1 0.0 0.0034 18.0 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KNZ76012.1 - 0.045 13.5 0.2 0.59 9.9 0.2 2.0 1 1 1 2 2 2 0 Aspartyl protease RNase_H PF00075.24 KNZ76013.1 - 0.044 14.0 0.3 0.075 13.2 0.3 1.3 1 0 0 1 1 1 0 RNase H rve PF00665.26 KNZ76013.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.6 1 1 1 2 2 2 0 Integrase core domain CorA PF01544.18 KNZ76015.1 - 4.6e-43 147.6 0.7 6.2e-43 147.2 0.7 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 KNZ76015.1 - 0.023 14.7 0.7 0.047 13.7 0.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uds1 PF15456.6 KNZ76016.1 - 5.9e-30 104.1 15.2 5.9e-30 104.1 15.2 6.2 4 2 2 6 6 6 1 Up-regulated During Septation HR1 PF02185.16 KNZ76016.1 - 0.00078 19.5 5.7 0.00078 19.5 5.7 7.0 7 3 1 8 8 8 1 Hr1 repeat Fer4_24 PF18109.1 KNZ76016.1 - 0.25 11.7 2.3 5.9 7.3 0.0 3.9 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain DegQ PF08181.11 KNZ76016.1 - 9.4 6.4 14.5 37 4.5 1.5 5.3 4 0 0 4 4 4 0 DegQ (SacQ) family Carbam_trans_C PF16861.5 KNZ76017.1 - 0.18 11.4 0.0 1.8 8.1 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus VIR_N PF15912.5 KNZ76019.1 - 8.7e-09 35.4 1.0 2.5e-08 33.9 1.0 1.6 1 1 0 1 1 1 1 Virilizer, N-terminal Sigma70_r2 PF04542.14 KNZ76019.1 - 0.13 12.0 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 region 2 ORMDL PF04061.14 KNZ76020.1 - 2.9e-54 182.6 2.2 3.6e-54 182.2 2.2 1.1 1 0 0 1 1 1 1 ORMDL family TTc_toxin_rep PF18807.1 KNZ76020.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Tripartite Tc toxins repeat THF_DHG_CYH_C PF02882.19 KNZ76021.1 - 2.7e-16 59.3 0.0 9.4e-08 31.5 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 KNZ76021.1 - 0.0067 16.9 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KNZ76021.1 - 0.012 15.7 0.1 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase IPP-2 PF04979.14 KNZ76022.1 - 1.9e-18 67.5 1.4 3.9e-18 66.5 1.4 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) RAP1 PF07218.11 KNZ76022.1 - 4.6 5.4 4.2 4.9 5.3 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NmrA PF05368.13 KNZ76023.1 - 2.9e-18 66.3 0.0 3.6e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ76023.1 - 0.00021 21.2 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Hemerythrin PF01814.23 KNZ76025.1 - 1.3e-07 32.3 1.0 0.00012 22.7 0.1 2.3 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain AAA PF00004.29 KNZ76026.1 - 3.1e-54 183.0 0.0 1.9e-39 135.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ76026.1 - 6.1e-11 42.7 0.4 4.8e-05 23.6 0.0 4.2 2 2 0 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 KNZ76026.1 - 6.4e-10 38.7 0.1 1.5e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KNZ76026.1 - 6.8e-10 39.6 0.1 0.0012 19.2 0.0 3.5 2 1 0 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 KNZ76026.1 - 1.9e-08 33.9 0.2 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 KNZ76026.1 - 3.8e-07 30.0 1.2 0.026 14.3 0.1 3.1 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNZ76026.1 - 6.9e-07 29.3 0.1 0.0028 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KNZ76026.1 - 1e-06 28.9 0.0 0.039 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KNZ76026.1 - 1.2e-06 28.7 0.4 3.8e-05 23.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 KNZ76026.1 - 1.6e-06 28.7 0.0 0.023 15.3 0.0 3.0 2 1 1 3 3 3 2 AAA domain TsaE PF02367.17 KNZ76026.1 - 1.1e-05 25.5 0.1 0.22 11.5 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KNZ76026.1 - 1.7e-05 24.3 0.1 0.012 15.0 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 KNZ76026.1 - 7.6e-05 22.6 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KNZ76026.1 - 7.6e-05 23.1 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 KNZ76026.1 - 7.8e-05 22.5 0.1 0.32 10.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_30 PF13604.6 KNZ76026.1 - 0.00012 21.9 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KNZ76026.1 - 0.00013 21.7 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF2075 PF09848.9 KNZ76026.1 - 0.0002 20.7 0.2 0.21 10.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 KNZ76026.1 - 0.00087 18.9 2.5 3.2 7.3 0.1 3.9 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 KNZ76026.1 - 0.001 19.1 0.0 0.43 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KNZ76026.1 - 0.0011 18.8 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNZ76026.1 - 0.0015 18.3 0.1 0.45 10.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 KNZ76026.1 - 0.0016 18.4 2.0 2.4 8.0 0.0 3.5 4 0 0 4 4 4 1 NACHT domain CDC48_2 PF02933.17 KNZ76026.1 - 0.0021 17.8 0.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 ABC_tran PF00005.27 KNZ76026.1 - 0.0024 18.4 0.3 0.22 12.0 0.1 2.6 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 KNZ76026.1 - 0.0034 16.6 0.1 0.99 8.5 0.1 2.3 2 0 0 2 2 2 1 NB-ARC domain Hydin_ADK PF17213.3 KNZ76026.1 - 0.0038 17.5 0.4 1.7 8.9 0.0 2.8 3 0 0 3 3 2 1 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 KNZ76026.1 - 0.0041 16.7 0.1 0.47 9.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 KNZ76026.1 - 0.0084 16.5 0.3 0.97 9.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KNZ76026.1 - 0.0087 16.3 0.0 0.77 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KNZ76026.1 - 0.017 14.6 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 KNZ76026.1 - 0.019 15.0 0.0 0.95 9.4 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KNZ76026.1 - 0.044 13.0 0.1 3.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin SKI PF01202.22 KNZ76026.1 - 0.054 13.6 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.12 KNZ76026.1 - 0.057 13.3 0.1 5.6 6.8 0.0 2.6 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 KNZ76026.1 - 0.087 12.2 2.6 2 7.7 0.1 3.0 3 1 0 3 3 3 0 KaiC Parvo_NS1 PF01057.17 KNZ76026.1 - 0.1 11.7 0.0 1.8 7.6 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Vps4_C PF09336.10 KNZ76026.1 - 0.13 12.2 0.0 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.18 KNZ76026.1 - 0.18 11.5 0.0 20 4.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase STIMATE PF12400.8 KNZ76027.1 - 4.2e-38 130.7 7.1 6.7e-38 130.1 7.1 1.3 1 0 0 1 1 1 1 STIMATE family DUF2009 PF09418.10 KNZ76028.1 - 9.6e-212 704.0 0.0 1.1e-211 703.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 KNZ76028.1 - 3e-06 27.3 5.2 5.5e-06 26.4 5.2 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 KNZ76028.1 - 0.00085 19.5 5.7 0.0019 18.4 5.7 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 KNZ76028.1 - 0.2 11.5 5.5 0.37 10.7 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) eIF3m_C_helix PF18005.1 KNZ76029.1 - 5.4e-13 48.4 1.1 1e-12 47.5 1.1 1.5 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix PCI PF01399.27 KNZ76029.1 - 4.7e-12 46.4 0.2 1.2e-10 41.9 0.0 2.3 2 0 0 2 2 2 1 PCI domain Pro-kuma_activ PF09286.11 KNZ76030.1 - 5e-36 124.1 0.0 9.3e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KNZ76030.1 - 0.0012 18.1 0.0 0.003 16.9 0.0 1.6 1 1 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.11 KNZ76031.1 - 3e-39 134.6 0.1 5.4e-39 133.7 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KNZ76031.1 - 0.0028 16.9 0.0 0.031 13.5 0.0 2.2 1 1 1 2 2 2 1 Subtilase family Hep_59 PF07052.11 KNZ76032.1 - 9.5e-30 103.5 0.5 9.5e-30 103.5 0.5 2.8 3 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Nuclease_act PF08133.11 KNZ76032.1 - 0.13 12.4 0.0 3.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Anticodon nuclease activator family Gti1_Pac2 PF09729.9 KNZ76033.1 - 1.5e-19 70.8 0.8 1.7e-19 70.6 0.8 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family DLIC PF05783.11 KNZ76034.1 - 6.2e-35 120.9 0.7 5.3e-28 98.1 0.0 3.7 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) AAA_16 PF13191.6 KNZ76034.1 - 0.079 13.3 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TIP41 PF04176.13 KNZ76035.1 - 4.8e-62 208.5 0.0 5.9e-62 208.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family TFIID_20kDa PF03847.13 KNZ76036.1 - 7.5e-28 96.8 0.2 1.3e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KNZ76036.1 - 0.0083 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KNZ76036.1 - 0.0092 16.0 0.0 0.019 15.1 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 KNZ76036.1 - 0.039 14.1 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold RRS1 PF04939.12 KNZ76037.1 - 5.7e-59 198.6 4.2 5.7e-59 198.6 4.2 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) SPRY PF00622.28 KNZ76038.1 - 3.5e-14 52.9 0.1 5.6e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 SPRY domain TFIIS_C PF01096.18 KNZ76039.1 - 2.8e-17 62.3 5.8 2.8e-17 62.3 5.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KNZ76039.1 - 6.5e-09 35.5 0.7 6.5e-09 35.5 0.7 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 KNZ76039.1 - 0.15 12.2 10.4 3.8 7.7 5.1 3.9 3 1 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 KNZ76039.1 - 0.19 11.7 10.4 0.61 10.1 1.3 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KNZ76039.1 - 0.45 10.0 11.0 5.8 6.5 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KNZ76039.1 - 0.9 9.5 13.9 4.6 7.3 0.1 4.1 3 1 1 4 4 4 0 PhnA Zinc-Ribbon zf-NADH-PPase PF09297.11 KNZ76039.1 - 2.1 8.0 10.7 26 4.6 2.4 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc-ribbons_6 PF07191.12 KNZ76039.1 - 3.9 7.5 11.3 0.45 10.5 0.3 2.8 2 1 0 2 2 2 0 zinc-ribbons RRM_1 PF00076.22 KNZ76040.1 - 2.5e-12 46.5 0.3 3.9e-08 33.0 0.1 3.9 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.6 KNZ76041.1 - 1.3e-18 67.3 0.0 6.3e-16 58.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KNZ76041.1 - 1.6e-18 66.4 0.0 3.4e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ76041.1 - 9e-15 54.7 0.0 1.9e-07 30.6 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ76041.1 - 1.8e-11 43.8 0.4 1.7e-08 34.0 0.1 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 KNZ76041.1 - 2.1e-06 27.8 0.1 0.00063 19.8 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KNZ76041.1 - 2.6e-05 24.3 0.3 0.0034 17.4 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ76041.1 - 0.00011 22.6 0.2 0.27 11.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KNZ76041.1 - 0.00013 22.2 0.0 0.048 13.9 0.0 3.0 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.6 KNZ76041.1 - 0.0013 19.0 0.0 0.0049 17.1 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ76041.1 - 0.035 13.1 0.1 0.64 9.0 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 KNZ76041.1 - 0.065 12.8 0.0 0.75 9.3 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KNZ76041.1 - 0.068 12.5 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Malic_M PF03949.15 KNZ76041.1 - 0.069 12.4 0.1 4.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_7 PF13241.6 KNZ76041.1 - 0.11 13.0 0.1 1.1 9.7 0.2 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KNZ76041.1 - 0.16 11.0 0.1 15 4.5 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A DNA_primase_lrg PF04104.14 KNZ76042.1 - 3.9e-85 285.5 0.0 5.3e-85 285.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit SMK-1 PF04802.15 KNZ76043.1 - 5.5e-85 284.0 0.9 1.8e-84 282.4 0.1 2.0 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 MOR2-PAG1_C PF14225.6 KNZ76043.1 - 0.12 12.2 0.7 0.28 11.0 0.7 1.5 1 0 0 1 1 1 0 Cell morphogenesis C-terminal MAS20 PF02064.15 KNZ76044.1 - 2.3e-37 128.0 0.6 4.6e-37 127.0 0.6 1.4 1 0 0 1 1 1 1 MAS20 protein import receptor SET PF00856.28 KNZ76044.1 - 2.4e-13 50.8 0.0 1.3e-12 48.4 0.0 2.2 2 1 0 2 2 2 1 SET domain SAF PF08666.12 KNZ76044.1 - 0.0075 16.9 0.9 3.7 8.2 0.0 2.9 3 0 0 3 3 3 2 SAF domain CLPTM1 PF05602.12 KNZ76046.1 - 1.4e-142 475.7 0.0 1.7e-142 475.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 KNZ76046.1 - 0.0021 17.8 3.7 0.0023 17.6 0.2 2.6 3 0 0 3 3 3 1 PQ loop repeat 2TM PF13239.6 KNZ76046.1 - 0.38 11.1 7.2 0.52 10.7 1.1 3.3 3 0 0 3 3 3 0 2TM domain 14-3-3 PF00244.20 KNZ76048.1 - 1.5e-106 354.9 3.0 1.7e-106 354.7 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 KNZ76048.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF TPR_19 PF14559.6 KNZ76048.1 - 0.61 10.6 3.3 0.73 10.4 0.2 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PGAP1 PF07819.13 KNZ76049.1 - 4.4e-54 183.6 0.0 6.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KNZ76049.1 - 6.1e-05 23.7 2.5 6.1e-05 23.7 2.5 2.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ76049.1 - 0.0046 16.3 0.5 0.0085 15.4 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KNZ76049.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 KNZ76049.1 - 0.096 12.3 0.2 0.45 10.1 0.2 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KNZ76049.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PLU-1 PF08429.11 KNZ76050.1 - 4.7e-55 187.1 1.9 4.7e-55 187.1 1.9 2.0 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.22 KNZ76050.1 - 6.9e-42 142.5 1.8 2.2e-41 140.9 0.3 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase ARID PF01388.21 KNZ76050.1 - 8.7e-18 64.8 0.2 4.8e-17 62.4 0.1 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 KNZ76050.1 - 1.3e-15 57.0 2.5 3.4e-15 55.7 2.5 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 KNZ76050.1 - 1.1e-14 54.0 45.0 6.3e-10 38.8 9.9 4.9 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.16 KNZ76050.1 - 5.1e-13 49.2 10.1 5.1e-13 49.2 10.1 3.1 4 0 0 4 4 4 1 C5HC2 zinc finger DUF5333 PF17267.2 KNZ76050.1 - 0.028 14.6 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5333) MerR-DNA-bind PF09278.11 KNZ76050.1 - 0.086 13.4 2.3 4.6 7.9 0.4 3.2 2 0 0 2 2 2 0 MerR, DNA binding zf-HC5HC2H PF13771.6 KNZ76050.1 - 6.4 7.1 32.7 0.96 9.7 4.3 4.6 4 0 0 4 4 4 0 PHD-like zinc-binding domain Abhydrolase_2 PF02230.16 KNZ76051.1 - 1.4e-58 198.3 0.0 2.4e-58 197.5 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KNZ76051.1 - 0.00013 21.3 0.2 1.4 8.1 0.1 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KNZ76051.1 - 0.0024 17.7 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ76051.1 - 0.0036 17.9 0.0 0.0057 17.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 KNZ76051.1 - 0.006 16.3 0.0 0.0099 15.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 KNZ76051.1 - 0.0075 15.9 0.4 2.1 7.9 0.2 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.18 KNZ76051.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.8 1 1 1 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.25 KNZ76051.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 KNZ76051.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Esterase_phd PF10503.9 KNZ76051.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase tRNA_m1G_MT PF01746.21 KNZ76052.1 - 1.2e-30 106.7 0.1 1.9e-30 106.1 0.1 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Methyltransf_23 PF13489.6 KNZ76053.1 - 1.3e-14 54.4 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ76053.1 - 6.4e-10 39.6 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ76053.1 - 1e-07 32.5 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ76053.1 - 1.5e-07 32.0 0.0 3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ76053.1 - 2.7e-05 24.0 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ76053.1 - 0.028 14.0 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 KNZ76053.1 - 0.038 13.0 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.19 KNZ76053.1 - 0.12 12.4 0.0 0.6 10.2 0.0 1.8 1 1 0 2 2 2 0 FtsJ-like methyltransferase FOXP-CC PF16159.5 KNZ76054.1 - 9.8e-07 29.3 11.4 0.0034 18.0 0.1 4.0 1 1 2 3 3 3 3 FOXP coiled-coil domain zf-C2H2 PF00096.26 KNZ76054.1 - 0.0014 19.0 10.4 0.04 14.4 0.5 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ76054.1 - 0.51 11.3 11.7 1.9 9.5 0.7 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KNZ76054.1 - 0.59 10.3 2.9 1.1 9.4 0.4 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger RNA_pol_Rpb2_6 PF00562.28 KNZ76056.1 - 3.6e-111 372.0 0.0 6.1e-111 371.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KNZ76056.1 - 2e-30 105.8 0.0 4e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 KNZ76056.1 - 1.6e-27 95.5 0.0 3.5e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 KNZ76056.1 - 8e-25 86.6 0.0 1.8e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 KNZ76056.1 - 6.7e-21 74.8 0.0 1.3e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KNZ76056.1 - 9.6e-19 67.6 0.2 8.2e-15 55.0 0.2 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 Nucleoporin2 PF04096.14 KNZ76057.1 - 2e-41 141.6 0.0 2.9e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KNZ76057.1 - 9.6e-14 52.0 285.6 7.6e-06 26.7 40.0 9.9 3 2 7 10 10 10 9 Nucleoporin FG repeat region HIG_1_N PF04588.13 KNZ76058.1 - 7.3e-05 22.9 0.9 0.00017 21.7 0.9 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MbeD_MobD PF04899.12 KNZ76058.1 - 0.063 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 MbeD/MobD like PAPS_reduct PF01507.19 KNZ76059.1 - 1.4e-40 139.2 0.0 1.7e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonuclease_3 PF00636.26 KNZ76060.1 - 3.2e-10 40.6 0.0 9.3e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KNZ76060.1 - 2.6e-07 30.9 0.0 1.4e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KNZ76060.1 - 5.3e-07 30.3 0.0 9.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Cyt-b5 PF00173.28 KNZ76061.1 - 9.1e-24 83.4 0.0 1.2e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Uso1_p115_C PF04871.13 KNZ76063.1 - 0.31 11.4 18.6 0.31 11.4 11.7 2.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KIAA1430 PF13879.6 KNZ76063.1 - 1.8 9.4 10.4 0.63 10.8 3.2 3.1 2 0 0 2 2 2 0 KIAA1430 homologue MCU PF04678.13 KNZ76063.1 - 2.1 8.4 5.0 3.8 7.6 1.9 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter CENP-H PF05837.12 KNZ76063.1 - 3.9 7.9 17.8 8.2 6.9 1.4 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KNZ76063.1 - 8.1 7.0 31.9 4.5 7.8 1.3 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region RRM_1 PF00076.22 KNZ76064.1 - 1.5e-21 76.0 0.3 9.7e-12 44.5 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KNZ76064.1 - 0.00043 20.2 0.1 0.002 18.1 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Ofd1_CTDD PF10637.9 KNZ76065.1 - 2.1e-76 256.7 0.0 2.4e-74 250.0 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KNZ76065.1 - 5.1e-30 104.0 0.0 1.3e-29 102.7 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KNZ76065.1 - 1.1e-14 55.1 0.0 3.5e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily POT1PC PF16686.5 KNZ76068.1 - 0.044 13.7 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein gag-asp_proteas PF13975.6 KNZ76069.1 - 9.5e-06 26.1 0.0 1.6e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76069.1 - 9e-05 23.1 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.24 KNZ76071.1 - 4.9e-07 29.6 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KNZ76071.1 - 0.055 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Chromo shadow domain Chromo PF00385.24 KNZ76072.1 - 1.5e-15 56.8 0.1 1.9e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ76072.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 DUF3123 PF11321.8 KNZ76073.1 - 0.83 10.3 4.6 1.3 9.7 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Tetraspanin PF00335.20 KNZ76074.1 - 0.0086 15.8 0.6 0.0086 15.8 0.6 1.7 1 1 1 2 2 2 1 Tetraspanin family Btz PF09405.10 KNZ76075.1 - 8.9e-10 38.9 1.6 8.9e-10 38.9 1.6 2.1 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding NKAP PF15692.5 KNZ76075.1 - 1.5 9.6 0.0 1.5 9.6 0.0 3.1 4 0 0 4 4 4 0 NF-kappa-B-activating protein Abhydrolase_1 PF00561.20 KNZ76076.1 - 3e-26 92.6 0.2 1.6e-24 86.9 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ76076.1 - 2.9e-15 57.5 3.1 4.9e-15 56.7 3.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ76076.1 - 2.4e-09 36.8 0.0 3.4e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 KNZ76076.1 - 1.1e-07 30.9 0.0 1.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family TFIIF_beta PF02270.15 KNZ76077.1 - 3.9e-21 74.9 0.1 6.3e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 KNZ76077.1 - 1.3e-20 74.5 0.0 2.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus ANAPC4_WD40 PF12894.7 KNZ76078.1 - 2.7e-08 34.0 0.0 0.0015 18.8 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ76078.1 - 7.6e-07 29.7 3.4 0.56 11.2 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.11 KNZ76078.1 - 3.5e-05 23.8 0.0 0.0098 15.8 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 KNZ76078.1 - 0.12 12.3 0.2 2.2 8.3 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat F-box-like PF12937.7 KNZ76079.1 - 0.00013 21.8 0.6 0.00013 21.8 0.6 2.1 2 0 0 2 2 2 1 F-box-like DUF4858 PF16150.5 KNZ76079.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) HMG_box PF00505.19 KNZ76081.1 - 5.1e-10 39.6 5.4 1.4e-09 38.2 5.4 1.7 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ76081.1 - 9.2e-09 35.8 2.3 1.7e-08 34.9 2.3 1.4 1 0 0 1 1 1 1 HMG-box domain HhH-GPD PF00730.25 KNZ76082.1 - 7e-11 42.5 0.0 1.1e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KNZ76082.1 - 0.0031 17.3 0.0 0.026 14.4 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix motif Helitron_like_N PF14214.6 KNZ76083.1 - 5.9e-06 26.6 0.4 1e-05 25.9 0.2 1.5 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KNZ76084.1 - 2e-26 93.4 0.0 2.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ76084.1 - 0.056 13.4 0.0 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 Inovirus Gp2 MitMem_reg PF13012.6 KNZ76085.1 - 0.034 14.5 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ76086.1 - 2.9e-103 345.9 0.0 3.4e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76086.1 - 1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KNZ76086.1 - 2.3e-06 25.9 0.0 3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ76086.1 - 0.00065 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KNZ76086.1 - 0.00092 19.0 0.3 0.15 11.7 0.2 2.5 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase 4HPAD_g_N PF18671.1 KNZ76086.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal zf-RVT PF13966.6 KNZ76087.1 - 0.0067 17.1 1.7 0.014 16.1 1.2 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase DUF521 PF04412.13 KNZ76087.1 - 0.028 13.2 0.1 0.033 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RT_RNaseH_2 PF17919.1 KNZ76089.1 - 1.8e-05 24.7 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ76089.1 - 0.031 14.6 0.0 0.099 12.9 0.0 1.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase G-alpha PF00503.20 KNZ76090.1 - 1.2e-113 379.9 1.5 1.4e-113 379.7 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ76090.1 - 1.8e-14 53.6 0.5 3.4e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ76090.1 - 2.5e-05 23.8 1.7 0.00024 20.5 0.0 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KNZ76090.1 - 0.0017 18.6 1.5 0.43 10.8 0.1 2.7 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase zf-CHC2 PF01807.20 KNZ76090.1 - 0.033 14.0 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 CHC2 zinc finger PAPA-1 PF04795.12 KNZ76092.1 - 2.7e-06 28.1 5.4 7.3e-06 26.7 5.4 1.7 1 0 0 1 1 1 1 PAPA-1-like conserved region HMG_box PF00505.19 KNZ76093.1 - 4e-13 49.6 0.1 7.5e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ76093.1 - 8.9e-05 23.0 0.0 0.00016 22.2 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain CTD PF12815.7 KNZ76095.1 - 0.51 10.9 9.6 2.2 8.9 4.1 2.3 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Helitron_like_N PF14214.6 KNZ76096.1 - 6e-25 88.6 0.0 8.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Acetyltransf_7 PF13508.7 KNZ76097.1 - 4e-06 27.1 0.0 6.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ76097.1 - 5.3e-06 26.4 0.0 7.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ76097.1 - 7.4e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family UPF0220 PF05255.11 KNZ76098.1 - 4e-55 185.9 0.0 4.8e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) TniQ PF06527.11 KNZ76100.1 - 0.077 13.7 0.0 0.74 10.5 0.0 2.0 2 0 0 2 2 2 0 TniQ RabGAP-TBC PF00566.18 KNZ76101.1 - 5.2e-22 78.6 0.5 7.8e-22 78.0 0.5 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PsbX PF06596.11 KNZ76101.1 - 4.3 7.4 4.8 1.8 8.6 0.4 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DBR1 PF05011.13 KNZ76102.1 - 7.1e-38 130.2 0.0 1.5e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KNZ76102.1 - 0.0041 17.6 0.3 0.0066 17.0 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 KNZ76102.1 - 0.061 12.6 0.0 0.28 10.5 0.0 1.9 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily SF3a60_bindingd PF12108.8 KNZ76102.1 - 0.27 11.1 1.4 0.67 9.9 1.4 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DDE_Tnp_4 PF13359.6 KNZ76103.1 - 1.6e-14 53.8 0.0 2.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 KNZ76103.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.4 1 1 0 1 1 1 1 Plant transposon protein Pyr_redox_3 PF13738.6 KNZ76104.1 - 7.4e-11 41.8 0.0 2.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KNZ76104.1 - 8.3e-10 37.7 0.1 2.3e-08 33.0 0.1 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KNZ76104.1 - 2.8e-05 23.4 0.0 0.029 13.5 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KNZ76104.1 - 3.6e-05 23.2 0.0 0.039 13.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ76104.1 - 0.00021 21.8 0.1 0.011 16.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ76104.1 - 0.0004 20.6 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KNZ76104.1 - 0.018 15.0 0.2 5.2 7.0 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KNZ76104.1 - 0.053 12.2 0.0 0.076 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 KNZ76104.1 - 0.061 12.7 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 KNZ76104.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 KNZ76104.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KNZ76104.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ76104.1 - 0.16 11.2 0.0 0.58 9.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KNZ76104.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 KNZ76105.1 - 8.1e-19 68.0 0.0 1.3e-16 60.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KNZ76105.1 - 1.3e-18 66.8 0.0 8.4e-17 60.8 0.0 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ76105.1 - 1.5e-17 63.8 0.7 1.7e-11 43.9 0.1 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ76105.1 - 7.8e-11 41.7 0.0 2.1e-06 27.1 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KNZ76105.1 - 6.5e-08 33.0 0.0 0.003 18.1 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ76105.1 - 2.5e-06 27.3 0.0 0.07 12.7 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ76105.1 - 0.00031 20.8 0.3 1 9.3 0.0 3.3 2 1 1 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 KNZ76105.1 - 0.00045 19.6 0.0 0.24 10.6 0.2 2.4 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KNZ76105.1 - 0.00091 19.4 0.0 0.0048 17.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KNZ76105.1 - 0.002 16.9 0.0 0.18 10.5 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 KNZ76105.1 - 0.004 16.3 0.0 0.91 8.5 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 KNZ76105.1 - 0.0045 16.4 0.0 0.1 12.0 0.0 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KNZ76105.1 - 0.0073 15.4 0.2 0.084 11.9 0.1 2.5 2 1 0 3 3 3 1 FAD binding domain GIDA PF01134.22 KNZ76105.1 - 0.017 14.2 0.1 0.5 9.4 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KNZ76105.1 - 0.018 14.4 0.0 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KNZ76105.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.18 KNZ76105.1 - 0.17 11.8 0.0 0.92 9.4 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Wzy_C PF04932.15 KNZ76106.1 - 0.043 13.4 1.2 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 O-Antigen ligase PMT PF02366.18 KNZ76106.1 - 0.071 12.7 6.8 1.9 8.0 1.6 2.1 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Phage_holin_3_6 PF07332.11 KNZ76106.1 - 0.23 11.5 0.0 0.23 11.5 0.0 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III PNKP-ligase_C PF16536.5 KNZ76107.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, C-terminal region F-box-like PF12937.7 KNZ76109.1 - 7.4e-06 25.8 0.7 3.5e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like Cation_efflux PF01545.21 KNZ76110.1 - 0.011 15.5 2.7 0.012 15.3 1.3 1.8 1 1 0 1 1 1 0 Cation efflux family FRB_dom PF08771.11 KNZ76111.1 - 0.067 13.6 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain F-box-like PF12937.7 KNZ76112.1 - 8.8e-09 35.1 0.0 3e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 F-box-like ZapB PF06005.12 KNZ76113.1 - 1.4e-07 31.8 13.0 4.9e-07 30.1 7.5 3.3 2 1 1 3 3 3 1 Cell division protein ZapB Atg14 PF10186.9 KNZ76113.1 - 0.00011 21.4 9.9 0.00023 20.4 9.9 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 KNZ76113.1 - 0.00016 21.7 19.5 0.0084 16.2 1.3 3.7 3 1 2 5 5 3 3 bZIP transcription factor ATG16 PF08614.11 KNZ76113.1 - 0.0019 18.5 11.9 0.0019 18.5 11.9 2.4 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 KNZ76113.1 - 0.0021 17.0 9.4 0.003 16.5 9.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like KASH_CCD PF14662.6 KNZ76113.1 - 0.0022 17.8 15.0 0.0022 17.8 15.0 2.1 2 1 0 2 2 1 1 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 KNZ76113.1 - 0.0028 18.1 8.9 0.0055 17.2 8.9 1.6 1 0 0 1 1 1 1 Fez1 JIP_LZII PF16471.5 KNZ76113.1 - 0.003 17.7 7.9 0.003 17.7 7.9 2.7 1 1 1 2 2 2 2 JNK-interacting protein leucine zipper II APG6_N PF17675.1 KNZ76113.1 - 0.0034 17.9 15.1 0.023 15.2 9.7 2.8 1 1 1 2 2 2 2 Apg6 coiled-coil region DUF2968 PF11180.8 KNZ76113.1 - 0.0037 16.9 2.3 0.007 16.0 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) bZIP_2 PF07716.15 KNZ76113.1 - 0.005 16.9 23.8 0.12 12.5 0.4 5.4 4 1 2 6 6 6 2 Basic region leucine zipper FlaC_arch PF05377.11 KNZ76113.1 - 0.012 16.0 13.3 0.017 15.5 2.7 4.1 2 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 KNZ76113.1 - 0.013 15.6 3.6 0.013 15.6 3.6 2.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SOGA PF11365.8 KNZ76113.1 - 0.016 16.3 14.4 0.1 13.7 5.0 3.8 2 1 2 4 4 4 0 Protein SOGA TPR_MLP1_2 PF07926.12 KNZ76113.1 - 0.017 15.1 3.6 0.017 15.1 3.6 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein STAT_alpha PF01017.20 KNZ76113.1 - 0.023 14.6 4.8 0.045 13.7 4.8 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF4145 PF13643.6 KNZ76113.1 - 0.025 14.7 1.3 0.51 10.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Cnn_1N PF07989.11 KNZ76113.1 - 0.026 14.7 7.8 0.026 14.7 7.8 3.3 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 GAS PF13851.6 KNZ76113.1 - 0.027 13.8 15.8 0.029 13.7 13.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 KNZ76113.1 - 0.027 13.8 5.9 0.049 12.9 5.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PhoU PF01895.19 KNZ76113.1 - 0.03 14.8 4.2 3.1 8.3 0.4 2.9 1 1 1 2 2 2 0 PhoU domain CENP-F_leu_zip PF10473.9 KNZ76113.1 - 0.064 13.3 18.4 0.044 13.8 14.7 2.5 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JAKMIP_CC3 PF16034.5 KNZ76113.1 - 0.065 13.2 12.7 0.085 12.8 1.7 2.7 1 1 1 2 2 2 0 JAKMIP CC3 domain HALZ PF02183.18 KNZ76113.1 - 0.069 13.4 22.1 0.21 11.8 2.1 4.3 3 1 2 5 5 3 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 KNZ76113.1 - 0.075 13.3 9.9 0.6 10.4 8.0 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CASP_C PF08172.12 KNZ76113.1 - 0.082 12.2 10.7 3.8 6.8 5.1 3.7 2 1 2 4 4 4 0 CASP C terminal TMPIT PF07851.13 KNZ76113.1 - 0.084 12.1 5.0 0.14 11.4 5.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein HDV_ag PF01517.18 KNZ76113.1 - 0.1 12.4 1.0 0.16 11.8 1.0 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Uso1_p115_C PF04871.13 KNZ76113.1 - 0.12 12.8 10.4 0.29 11.5 10.4 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 KNZ76113.1 - 0.14 11.0 10.9 0.23 10.3 10.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 KNZ76113.1 - 0.15 12.5 16.6 0.25 11.7 2.9 3.7 2 1 2 4 4 4 0 Csm1 N-terminal domain RTBV_P46 PF06216.11 KNZ76113.1 - 0.15 10.9 5.1 0.041 12.8 2.1 1.5 2 0 0 2 2 1 0 Rice tungro bacilliform virus P46 protein CtIP_N PF10482.9 KNZ76113.1 - 0.15 12.1 17.8 0.033 14.2 3.9 3.1 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain TMCO5 PF14992.6 KNZ76113.1 - 0.22 11.1 14.0 0.12 12.0 11.9 1.6 2 0 0 2 2 1 0 TMCO5 family DivIC PF04977.15 KNZ76113.1 - 0.23 11.3 17.0 1.4 8.8 2.8 3.9 2 1 2 4 4 3 0 Septum formation initiator Leu_zip PF15294.6 KNZ76113.1 - 0.24 10.9 14.5 1.7 8.1 12.9 2.2 1 1 1 2 2 2 0 Leucine zipper BLOC1_2 PF10046.9 KNZ76113.1 - 0.25 11.6 7.3 2.6 8.4 6.0 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 KNZ76113.1 - 0.26 11.8 8.3 5.2 7.6 1.1 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 KNZ76113.1 - 0.27 11.3 3.8 0.97 9.5 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 KNZ76113.1 - 0.31 11.7 14.1 1.5 9.5 10.8 3.4 2 1 1 3 3 3 0 Initiation control protein YabA Mod_r PF07200.13 KNZ76113.1 - 0.35 11.0 14.1 0.22 11.6 11.0 2.2 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.6 KNZ76113.1 - 0.41 10.0 3.8 0.63 9.3 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_3 PF13758.6 KNZ76113.1 - 0.46 10.6 4.4 23 5.1 0.0 3.1 2 1 0 3 3 2 0 Prefoldin subunit Cep57_CLD_2 PF14197.6 KNZ76113.1 - 0.49 10.5 19.3 0.29 11.2 3.1 4.0 4 1 1 5 5 3 0 Centrosome localisation domain of PPC89 DMPK_coil PF08826.10 KNZ76113.1 - 0.56 10.4 12.1 1.7 8.8 4.7 2.6 1 1 1 2 2 2 0 DMPK coiled coil domain like Syntaxin-6_N PF09177.11 KNZ76113.1 - 0.76 10.4 8.5 4.3 8.0 8.5 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.9 KNZ76113.1 - 0.76 10.0 13.1 0.74 10.0 6.7 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF724 PF05266.14 KNZ76113.1 - 0.96 9.3 15.5 0.11 12.3 8.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 KNZ76113.1 - 0.98 9.5 10.7 0.47 10.5 7.9 1.8 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 KNZ76113.1 - 1.1 9.9 8.4 1.6 9.4 2.1 2.8 1 1 1 2 2 2 0 SlyX CENP-H PF05837.12 KNZ76113.1 - 1.2 9.6 14.9 8 6.9 10.8 3.4 2 1 2 4 4 4 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 KNZ76113.1 - 1.2 6.9 3.8 1.6 6.5 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI3K_P85_iSH2 PF16454.5 KNZ76113.1 - 1.6 8.3 15.5 1.2 8.7 12.7 2.2 2 1 0 2 2 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APC_N_CC PF16689.5 KNZ76113.1 - 2 8.5 18.4 1.4 9.0 2.1 4.0 2 1 2 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Shugoshin_N PF07558.11 KNZ76113.1 - 2.4 8.1 16.8 1.2 9.1 1.1 4.7 3 1 2 5 5 5 0 Shugoshin N-terminal coiled-coil region BRE1 PF08647.11 KNZ76113.1 - 2.4 8.3 11.6 5.9 7.0 10.4 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Cep57_MT_bd PF06657.13 KNZ76113.1 - 2.6 8.6 8.1 5.5 7.5 5.6 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FapA PF03961.13 KNZ76113.1 - 3.2 6.3 10.1 0.13 10.9 2.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF848 PF05852.11 KNZ76113.1 - 4.1 7.5 10.0 28 4.8 8.5 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) GIT_CC PF16559.5 KNZ76113.1 - 4.3 7.3 13.3 3.3 7.7 5.3 3.7 2 1 2 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Herpes_UL6 PF01763.16 KNZ76113.1 - 7.2 5.0 9.9 5.7 5.3 2.0 2.2 1 1 1 2 2 2 0 Herpesvirus UL6 like LPP PF04728.13 KNZ76113.1 - 7.2 7.1 7.8 6.6 7.2 2.2 3.4 2 1 2 4 4 3 0 Lipoprotein leucine-zipper USP8_interact PF08941.10 KNZ76113.1 - 9.8 5.9 6.9 11 5.8 1.2 2.7 1 1 1 2 2 2 0 USP8 interacting Transket_pyr PF02779.24 KNZ76114.1 - 3e-59 199.7 0.0 4.2e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 KNZ76114.1 - 7.2e-45 152.4 0.0 1.2e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 KNZ76114.1 - 2.5e-27 95.6 0.0 7.7e-27 94.0 0.0 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component SH3_12 PF18129.1 KNZ76114.1 - 0.03 14.4 0.1 0.063 13.4 0.1 1.5 1 0 0 1 1 1 0 Xrn1 SH3-like domain RVP_2 PF08284.11 KNZ76115.1 - 0.0077 16.0 0.1 0.009 15.8 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Aldo_ket_red PF00248.21 KNZ76117.1 - 1.8e-71 240.7 0.0 2.2e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TH1 PF04858.13 KNZ76117.1 - 0.029 13.0 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 TH1 protein GPI-anchored PF10342.9 KNZ76118.1 - 1.9e-08 34.9 0.6 5.5e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Amidase PF01425.21 KNZ76119.1 - 5.6e-100 335.4 0.0 8.4e-100 334.8 0.0 1.3 1 1 0 1 1 1 1 Amidase ABC2_membrane PF01061.24 KNZ76120.1 - 4.5e-77 258.2 46.8 2.8e-42 144.5 16.1 3.4 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 KNZ76120.1 - 1e-40 137.5 4.2 4.3e-31 106.7 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 KNZ76120.1 - 3.3e-36 124.8 0.0 1.6e-17 64.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 KNZ76120.1 - 1.4e-07 32.0 0.0 3.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KNZ76120.1 - 1.9e-06 28.3 0.0 0.00048 20.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KNZ76120.1 - 1.8e-05 24.7 0.1 0.00022 21.2 0.0 2.4 3 0 0 3 3 2 1 RsgA GTPase AAA_25 PF13481.6 KNZ76120.1 - 1.8e-05 24.4 0.0 0.0078 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KNZ76120.1 - 4.9e-05 23.3 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KNZ76120.1 - 7.5e-05 23.0 0.1 0.048 13.9 0.1 3.2 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KNZ76120.1 - 0.00072 18.8 21.2 0.00072 18.8 21.2 3.7 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 KNZ76120.1 - 0.00074 19.2 0.1 0.24 11.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KNZ76120.1 - 0.0013 19.3 0.0 1.6 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KNZ76120.1 - 0.0013 18.6 0.1 0.049 13.5 0.1 2.4 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 KNZ76120.1 - 0.0054 16.2 0.0 0.13 11.7 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KNZ76120.1 - 0.0054 16.8 0.1 0.75 9.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 KNZ76120.1 - 0.0073 16.5 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KNZ76120.1 - 0.0079 15.9 0.0 1.1 8.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 KNZ76120.1 - 0.0086 15.9 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 Deoxynucleoside kinase RNA_helicase PF00910.22 KNZ76120.1 - 0.02 15.3 0.0 0.96 9.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KNZ76120.1 - 0.077 13.0 0.1 0.53 10.3 0.1 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KNZ76120.1 - 0.079 13.2 0.0 6.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 KNZ76120.1 - 0.094 12.6 0.0 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 KNZ76120.1 - 0.096 13.2 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ76120.1 - 0.1 13.0 0.0 3 8.3 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KNZ76120.1 - 0.14 11.7 0.3 0.68 9.5 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KNZ76120.1 - 0.15 12.3 0.0 1.4 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KNZ76120.1 - 0.17 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Glyco_hydro_7 PF00840.20 KNZ76121.1 - 0.0021 16.9 0.0 0.0022 16.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pkinase PF00069.25 KNZ76122.1 - 8.1e-31 107.3 0.0 8.8e-15 54.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76122.1 - 1.4e-13 50.7 0.0 5.5e-06 25.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ76122.1 - 0.0057 16.6 0.3 0.045 13.7 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ76122.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ76122.1 - 0.11 11.8 0.0 3.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Kinase-like E1-E2_ATPase PF00122.20 KNZ76123.1 - 2e-50 170.9 0.0 1.2e-49 168.3 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KNZ76123.1 - 1.6e-19 71.1 0.4 3.5e-19 69.9 0.4 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KNZ76123.1 - 1.7e-12 46.9 0.0 4.6e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNZ76123.1 - 0.00018 21.3 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ76123.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) MFS_1 PF07690.16 KNZ76124.1 - 5.6e-39 134.1 25.6 6.2e-39 133.9 25.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily BTP PF05232.12 KNZ76124.1 - 0.0016 18.5 0.1 0.0016 18.5 0.1 3.6 3 1 0 3 3 3 2 Chlorhexidine efflux transporter Peptidase_U4 PF03419.13 KNZ76124.1 - 4.9 6.4 19.6 0.044 13.1 8.3 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA NUDIX PF00293.28 KNZ76125.1 - 4.9e-09 36.3 0.3 6.1e-09 36.0 0.3 1.3 1 1 0 1 1 1 1 NUDIX domain CsbD PF05532.12 KNZ76126.1 - 4.1e-08 33.0 14.0 0.00014 21.6 1.9 2.1 1 1 1 2 2 2 2 CsbD-like Cytomega_UL20A PF05984.12 KNZ76126.1 - 0.23 11.8 3.9 0.29 11.4 3.9 1.2 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein MFS_1 PF07690.16 KNZ76127.1 - 1.4e-35 122.9 27.3 1.4e-35 122.9 27.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily BTP PF05232.12 KNZ76127.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.8 3 1 1 4 4 4 0 Chlorhexidine efflux transporter Glyco_transf_24 PF18404.1 KNZ76128.1 - 9.6e-144 477.7 3.0 1.4e-143 477.2 3.0 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KNZ76128.1 - 5e-59 200.3 0.0 8.9e-58 196.2 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KNZ76128.1 - 3.8e-52 176.9 0.0 1.1e-51 175.5 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KNZ76128.1 - 6.5e-38 129.2 0.1 3.6e-37 126.8 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 KNZ76128.1 - 1e-36 125.8 0.0 3.8e-36 124.0 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KNZ76128.1 - 8.2e-30 104.3 0.0 6.3e-21 75.3 0.0 4.0 4 0 0 4 4 4 3 Thioredoxin-like domain Glyco_transf_8 PF01501.20 KNZ76128.1 - 6.9e-06 25.8 0.1 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 NMD3 PF04981.13 KNZ76129.1 - 2.8e-81 272.6 0.8 3.9e-81 272.1 0.8 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KNZ76129.1 - 0.003 17.5 4.8 0.55 10.3 1.3 2.7 1 1 1 2 2 2 2 Double zinc ribbon NinF PF05810.12 KNZ76129.1 - 0.028 14.3 0.4 0.11 12.3 0.4 2.0 1 0 0 1 1 1 0 NinF protein Rpr2 PF04032.16 KNZ76129.1 - 0.32 11.3 3.7 47 4.4 2.2 3.3 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF35_N PF12172.8 KNZ76129.1 - 1.2 9.0 10.1 0.61 10.0 0.6 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Methyltransf_23 PF13489.6 KNZ76130.1 - 1.1e-10 41.6 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ76130.1 - 3e-07 31.0 0.0 5.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ76130.1 - 1.9e-05 25.3 0.0 3.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ76130.1 - 3.7e-05 24.4 0.0 0.00012 22.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ76130.1 - 0.00034 20.4 0.0 0.0017 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DUF5343 PF17278.2 KNZ76131.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5343) Helitron_like_N PF14214.6 KNZ76134.1 - 1.3e-05 25.5 0.7 2.2e-05 24.8 0.3 1.6 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ76135.1 - 1.2e-53 182.6 0.4 1.7e-53 182.1 0.4 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76135.1 - 1.2e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ76135.1 - 0.01 16.3 0.0 0.033 14.6 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 KNZ76135.1 - 0.015 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Med29 PF11568.8 KNZ76135.1 - 0.029 14.6 0.2 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Mediator complex subunit 29 ResIII PF04851.15 KNZ76135.1 - 0.068 13.2 0.0 0.19 11.7 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ76135.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APH PF01636.23 KNZ76136.1 - 1e-20 74.7 0.0 1.5e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ76136.1 - 1.2e-05 25.1 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase HipA_C PF07804.12 KNZ76136.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 HipA-like C-terminal domain RIO1 PF01163.22 KNZ76136.1 - 0.12 12.0 0.1 0.36 10.4 0.1 1.7 2 0 0 2 2 2 0 RIO1 family DUF676 PF05057.14 KNZ76139.1 - 4.2e-33 114.7 0.0 5.9e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 KNZ76139.1 - 0.0011 18.8 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 KNZ76139.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 KNZ76139.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Rtf2 PF04641.12 KNZ76140.1 - 5e-69 232.6 0.3 6.1e-69 232.3 0.3 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger RE_MamI PF09567.10 KNZ76140.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 MamI restriction endonuclease zf-C3HC4_4 PF15227.6 KNZ76140.1 - 0.027 14.6 2.2 0.076 13.2 1.2 2.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 KNZ76140.1 - 0.13 12.4 0.7 0.34 11.1 0.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain MRP-S31 PF15433.6 KNZ76140.1 - 0.18 11.5 0.9 0.26 10.9 0.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 zf-C2H2_4 PF13894.6 KNZ76140.1 - 0.47 11.4 2.2 1.5 9.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger UPF0203 PF05254.12 KNZ76141.1 - 6.2e-25 87.2 1.9 7.5e-25 87.0 1.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 KNZ76141.1 - 0.019 15.2 1.1 3.7 7.9 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 KNZ76141.1 - 0.025 14.8 3.7 0.66 10.2 0.3 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein ADH_zinc_N PF00107.26 KNZ76142.1 - 1.8e-15 57.1 0.0 3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ76142.1 - 0.00019 22.5 0.0 0.00045 21.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ76142.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.6 KNZ76142.1 - 0.058 13.9 0.0 1.4 9.4 0.0 2.7 2 1 0 2 2 2 0 CoA binding domain EMP24_GP25L PF01105.24 KNZ76143.1 - 2.2e-44 151.6 0.0 2.7e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 KNZ76143.1 - 0.059 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 SdrD B-like domain SCA7 PF08313.12 KNZ76144.1 - 9.1e-28 96.0 0.1 9.1e-28 96.0 0.1 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-TRAF PF02176.18 KNZ76144.1 - 0.01 16.5 1.2 0.057 14.1 0.2 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger MAS20 PF02064.15 KNZ76144.1 - 0.016 15.3 1.7 0.03 14.4 1.7 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Sgf11 PF08209.11 KNZ76144.1 - 0.049 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) zf_C2H2_13 PF18508.1 KNZ76144.1 - 0.049 13.2 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 Zinc finger domain zf_C2HC_14 PF18574.1 KNZ76144.1 - 0.064 13.1 1.7 0.12 12.2 1.7 1.3 1 0 0 1 1 1 0 C2HC Zing finger domain zf_UBZ PF18439.1 KNZ76144.1 - 0.064 12.9 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Rrn6 PF10214.9 KNZ76144.1 - 0.094 11.2 1.3 0.12 10.8 1.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MFAP1 PF06991.11 KNZ76144.1 - 0.24 11.2 7.1 0.37 10.6 7.1 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing TFIID_30kDa PF03540.13 KNZ76145.1 - 2e-25 88.5 0.0 3e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_60s PF00428.19 KNZ76145.1 - 0.016 15.8 5.1 1.2 9.8 0.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Bromo_TP PF07524.13 KNZ76145.1 - 0.027 14.5 0.0 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated DUF3464 PF11947.8 KNZ76145.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Ribosomal_L11_N PF03946.14 KNZ76145.1 - 0.14 12.0 0.2 6.3 6.7 0.1 2.7 2 1 1 3 3 3 0 Ribosomal protein L11, N-terminal domain CCDC53 PF10152.9 KNZ76145.1 - 0.55 10.6 3.7 0.86 10.0 3.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Fungal_trans PF04082.18 KNZ76146.1 - 9e-18 64.2 0.2 1.9e-17 63.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpc4 PF05132.14 KNZ76147.1 - 2.4e-31 109.2 0.1 2.4e-31 109.2 0.1 2.4 3 0 0 3 3 3 1 RNA polymerase III RPC4 Pribosyltran PF00156.27 KNZ76148.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MLD PF11647.8 KNZ76148.1 - 0.11 12.7 0.1 0.26 11.6 0.0 1.6 2 0 0 2 2 2 0 Membrane Localization Domain Aconitase PF00330.20 KNZ76149.1 - 2.4e-110 369.7 0.0 2.5e-109 366.4 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KNZ76149.1 - 6.3e-20 71.8 0.1 1.4e-19 70.7 0.1 1.6 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 KNZ76149.1 - 0.072 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) SRPRB PF09439.10 KNZ76150.1 - 1.3e-21 76.8 0.0 2e-21 76.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 KNZ76150.1 - 7.6e-14 51.5 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ76150.1 - 8.1e-09 35.6 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KNZ76150.1 - 7e-07 28.8 0.0 8.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KNZ76150.1 - 0.00059 20.1 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KNZ76150.1 - 0.0032 17.0 0.0 1.8 8.1 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain G-alpha PF00503.20 KNZ76150.1 - 0.009 15.2 0.0 0.61 9.2 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 KNZ76150.1 - 0.011 16.2 0.2 0.019 15.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KNZ76150.1 - 0.015 14.9 0.1 0.028 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 KNZ76150.1 - 0.015 14.8 0.0 0.054 13.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 KNZ76150.1 - 0.076 12.4 0.0 0.55 9.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 KNZ76150.1 - 0.093 13.1 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ76150.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 KNZ76150.1 - 0.11 12.1 0.2 10 5.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 KNZ76150.1 - 0.11 12.0 0.0 0.92 9.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ENTH PF01417.20 KNZ76151.1 - 4.3e-51 172.2 0.1 7.6e-51 171.4 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KNZ76151.1 - 0.0001 21.4 0.0 0.0001 21.4 0.0 2.3 2 0 0 2 2 2 1 ANTH domain UIM PF02809.20 KNZ76151.1 - 0.027 14.4 12.3 0.18 11.8 2.3 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif Pkinase PF00069.25 KNZ76152.1 - 1.3e-60 205.0 0.0 3e-60 203.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76152.1 - 1.7e-30 106.2 0.0 2.6e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ76152.1 - 2.1e-08 33.8 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ76152.1 - 0.00016 20.6 0.0 0.00034 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KNZ76152.1 - 0.00033 20.1 2.6 0.00099 18.5 0.0 2.7 4 0 0 4 4 4 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ76152.1 - 0.0022 18.0 0.2 0.0047 16.9 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ76152.1 - 0.0065 15.5 0.1 0.0065 15.5 0.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KNZ76152.1 - 0.019 14.0 0.1 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Guanylate_kin PF00625.21 KNZ76153.1 - 5.9e-63 211.8 0.0 6.9e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 KNZ76153.1 - 1.7e-07 31.8 0.0 3.6e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KNZ76153.1 - 5.9e-07 29.7 0.0 4.4e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNZ76153.1 - 0.00021 21.6 0.0 0.00042 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KNZ76153.1 - 0.00038 20.5 0.0 0.00049 20.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ76153.1 - 0.00095 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ATPase_2 PF01637.18 KNZ76153.1 - 0.0054 16.7 0.0 0.028 14.3 0.0 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KNZ76153.1 - 0.006 17.0 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 KNZ76153.1 - 0.01 16.3 0.0 0.013 16.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KNZ76153.1 - 0.013 16.0 0.0 0.04 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 KNZ76153.1 - 0.015 15.3 0.0 0.088 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KNZ76153.1 - 0.028 14.2 0.1 0.06 13.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ76153.1 - 0.032 14.7 0.0 0.11 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KNZ76153.1 - 0.036 13.8 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 KNZ76153.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KNZ76153.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 KNZ76153.1 - 0.09 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KNZ76153.1 - 0.096 12.3 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KNZ76153.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KNZ76153.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_membrane PF00664.23 KNZ76154.1 - 4e-65 220.2 31.1 1.5e-34 119.9 12.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ76154.1 - 5.1e-54 182.5 0.0 3.2e-31 108.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ76154.1 - 4.5e-06 26.2 0.0 0.15 11.5 0.0 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KNZ76154.1 - 3.4e-05 24.3 0.3 0.034 14.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 KNZ76154.1 - 3.5e-05 23.9 0.4 0.33 11.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 KNZ76154.1 - 7e-05 22.8 1.2 6.4 6.5 0.0 3.8 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KNZ76154.1 - 0.0015 18.4 0.1 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNZ76154.1 - 0.0019 17.9 0.4 1.1 9.0 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 KNZ76154.1 - 0.0058 16.7 0.4 4 7.5 0.1 2.4 2 0 0 2 2 2 2 Dynamin family DUF4574 PF15141.6 KNZ76154.1 - 0.011 15.6 0.1 0.057 13.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 IstB_IS21 PF01695.17 KNZ76154.1 - 0.013 15.2 0.0 7.9 6.2 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KNZ76154.1 - 0.014 14.4 0.0 0.58 9.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 KNZ76154.1 - 0.023 14.4 0.5 3.4 7.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KNZ76154.1 - 0.026 15.0 0.1 5.5 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KNZ76154.1 - 0.032 13.8 0.4 0.88 9.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 KNZ76154.1 - 0.032 13.5 0.3 3.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 KNZ76154.1 - 0.21 11.8 0.3 32 4.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 KNZ76154.1 - 0.22 11.8 1.6 4.7 7.5 0.1 3.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 KNZ76154.1 - 1.5 8.9 7.4 2.8 7.9 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain SDH_alpha PF03313.15 KNZ76156.1 - 8.2e-93 310.8 0.1 1.3e-92 310.2 0.1 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 KNZ76156.1 - 1.3e-43 149.0 0.0 3.7e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 Serine dehydratase beta chain Clathrin PF00637.20 KNZ76157.1 - 5.4e-203 665.0 28.8 2.3e-32 111.8 0.1 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KNZ76157.1 - 4.7e-39 130.8 1.2 5.5e-07 29.6 0.1 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KNZ76157.1 - 4.1e-30 103.5 0.1 1.4e-29 101.7 0.1 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 KNZ76157.1 - 8.2e-12 44.3 1.9 3.7e-11 42.2 0.1 2.9 3 0 0 3 3 3 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 KNZ76157.1 - 0.0011 18.1 5.2 0.31 10.0 0.1 3.9 4 0 0 4 4 4 2 Coatomer WD associated region TPR_7 PF13176.6 KNZ76157.1 - 0.0072 16.3 5.8 4.6 7.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 KNZ76157.1 - 0.013 15.7 0.3 6.9 7.2 0.0 5.0 6 0 0 6 6 5 0 PPR repeat TPR_1 PF00515.28 KNZ76157.1 - 0.1 12.5 6.8 15 5.6 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ76157.1 - 0.12 13.3 11.0 9 7.4 0.0 7.4 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ76157.1 - 0.17 12.0 10.4 42 4.6 0.4 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ76157.1 - 7.5 7.0 12.4 7.9 7.0 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Ras PF00071.22 KNZ76158.1 - 4.5e-48 162.9 0.0 5.2e-48 162.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ76158.1 - 6.9e-18 65.0 0.0 1.3e-17 64.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ76158.1 - 0.00049 19.6 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KNZ76158.1 - 0.011 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KNZ76158.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1640 PF07798.11 KNZ76159.1 - 1.3e-61 207.7 11.4 1.5e-61 207.5 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DotU PF09850.9 KNZ76159.1 - 0.043 13.5 3.7 2.3 7.9 0.0 2.9 2 1 1 3 3 3 0 Type VI secretion system protein DotU KIAA1430 PF13879.6 KNZ76159.1 - 0.067 13.9 5.7 0.11 13.3 5.7 1.3 1 0 0 1 1 1 0 KIAA1430 homologue Uso1_p115_C PF04871.13 KNZ76159.1 - 1.2 9.5 9.6 0.34 11.3 4.0 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FlaC_arch PF05377.11 KNZ76159.1 - 1.2 9.5 6.1 0.32 11.4 0.7 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) COG5 PF10392.9 KNZ76159.1 - 1.2 9.3 6.4 2.5 8.3 0.5 2.9 1 1 2 3 3 3 0 Golgi transport complex subunit 5 Fungal_TACC PF12709.7 KNZ76159.1 - 2.3 8.7 8.0 1.4 9.4 3.6 2.5 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 KNZ76159.1 - 4.7 7.1 9.1 1.5 8.7 4.2 2.3 1 1 1 2 2 2 0 Septum formation initiator Fib_alpha PF08702.10 KNZ76159.1 - 8.9 6.5 10.3 1.2 9.3 2.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_C12 PF01088.21 KNZ76160.1 - 2.2e-48 164.8 0.0 4e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40 PF00400.32 KNZ76160.1 - 2.5e-16 59.7 5.8 4.5e-05 24.1 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Integrase_H2C2 PF17921.1 KNZ76160.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain ANAPC4_WD40 PF12894.7 KNZ76160.1 - 0.077 13.3 0.0 1 9.7 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain UBA PF00627.31 KNZ76161.1 - 0.00069 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.17 KNZ76161.1 - 0.0038 17.2 2.2 14 6.1 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ76161.1 - 0.03 14.2 1.1 35 4.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 KNZ76161.1 - 0.067 13.3 0.1 0.51 10.5 0.0 2.4 2 0 0 2 2 2 0 DnaJ domain Chromo PF00385.24 KNZ76162.1 - 6.1e-09 35.7 0.1 1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KNZ76162.1 - 0.0037 17.1 0.0 0.0061 16.4 0.0 1.5 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Glyco_hydro_88 PF07470.13 KNZ76165.1 - 8.9e-20 71.0 0.1 1.3e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 SET PF00856.28 KNZ76166.1 - 1.6e-10 41.6 0.0 4e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 SET domain S6PP_C PF08472.10 KNZ76166.1 - 0.022 14.6 0.0 0.087 12.7 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF2153 PF09921.9 KNZ76166.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) Sod_Fe_C PF02777.18 KNZ76168.1 - 6.3e-35 119.4 0.1 1.2e-34 118.5 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KNZ76168.1 - 1.1e-31 109.2 4.3 1.2e-31 109.0 2.4 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ocnus PF05005.15 KNZ76168.1 - 0.14 12.3 0.0 1.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) PIF1 PF05970.14 KNZ76169.1 - 3.1e-27 95.7 0.0 3.5e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ76169.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Herpes_Helicase PF02689.14 KNZ76170.1 - 8.9e-05 20.6 0.0 9.3e-05 20.6 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ76170.1 - 0.1 12.5 0.3 0.24 11.3 0.2 1.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Herpeto_peptide PF14409.6 KNZ76172.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon Aldo_ket_red PF00248.21 KNZ76174.1 - 3.4e-40 138.1 0.0 3.9e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3089 PF11288.8 KNZ76175.1 - 0.039 13.5 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) RVT_thumb PF06817.14 KNZ76176.1 - 2.3 8.1 5.3 0.97 9.3 0.7 2.5 2 1 1 3 3 3 0 Reverse transcriptase thumb domain Pectate_lyase_3 PF12708.7 KNZ76178.1 - 8.6e-85 283.9 8.4 3.9e-70 236.0 2.9 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KNZ76178.1 - 0.0019 17.9 0.2 0.0098 15.6 0.1 2.3 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Nup84_Nup100 PF04121.13 KNZ76179.1 - 4.3e-158 527.7 0.0 5e-158 527.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.14 KNZ76179.1 - 4.1e-05 22.3 0.3 6.4e-05 21.6 0.3 1.2 1 0 0 1 1 1 1 Nup93/Nic96 TPR_14 PF13428.6 KNZ76179.1 - 2.5 9.2 7.2 1.6 9.7 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF3716 PF12511.8 KNZ76180.1 - 0.43 10.6 4.0 0.18 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) RT_RNaseH PF17917.1 KNZ76181.1 - 1.8e-10 41.0 0.0 3.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76181.1 - 1.4e-08 34.7 0.1 4.6e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase POT1PC PF16686.5 KNZ76181.1 - 0.039 13.8 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein gag-asp_proteas PF13975.6 KNZ76182.1 - 1.5e-07 31.9 0.0 2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76182.1 - 3.2e-06 27.7 0.0 5.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ76182.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.12 KNZ76182.1 - 0.078 12.7 0.2 0.25 11.1 0.1 1.7 1 1 1 2 2 2 0 Putative peptidase (DUF1758) Calcyon PF06387.11 KNZ76184.1 - 0.21 11.5 0.1 0.32 10.9 0.1 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) FHA PF00498.26 KNZ76186.1 - 1.4e-15 57.3 0.4 5.1e-15 55.6 0.1 2.2 2 1 0 2 2 2 1 FHA domain Lipoprotein_7 PF01540.16 KNZ76186.1 - 0.00091 18.6 0.2 0.0018 17.7 0.2 1.4 1 0 0 1 1 1 1 Adhesin lipoprotein Yop-YscD_cpl PF16697.5 KNZ76186.1 - 0.0042 17.4 0.1 0.026 14.8 0.0 2.4 3 0 0 3 3 2 1 Inner membrane component of T3SS, cytoplasmic domain Phage_GP20 PF06810.11 KNZ76186.1 - 0.03 14.1 14.4 0.14 11.9 1.6 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF4407 PF14362.6 KNZ76186.1 - 0.039 13.3 10.0 0.09 12.1 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TRAF_BIRC3_bd PF16673.5 KNZ76186.1 - 0.065 13.0 2.5 0.073 12.9 0.1 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Med3 PF11593.8 KNZ76186.1 - 0.12 11.6 12.4 0.029 13.6 7.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1664 PF07889.12 KNZ76186.1 - 0.12 12.4 13.5 0.92 9.6 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KNZ76186.1 - 0.65 10.2 5.4 4 7.6 0.0 2.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 KNZ76186.1 - 0.82 10.0 13.9 0.76 10.1 0.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 KNZ76186.1 - 0.96 10.0 10.7 2.3 8.8 1.3 3.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal PspA_IM30 PF04012.12 KNZ76186.1 - 1 8.9 21.9 1.2 8.7 10.4 2.6 2 0 0 2 2 2 0 PspA/IM30 family DUF572 PF04502.13 KNZ76186.1 - 1.5 8.4 24.4 0.012 15.2 9.8 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF572) DUF3552 PF12072.8 KNZ76186.1 - 5.4 6.4 17.0 2.6 7.4 12.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) COG6 PF06419.11 KNZ76186.1 - 9.9 4.2 9.4 1 7.5 1.8 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 WW PF00397.26 KNZ76187.1 - 2.7e-09 36.9 6.0 8.6e-09 35.3 6.0 1.9 1 0 0 1 1 1 1 WW domain ECR1_N PF14382.6 KNZ76188.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Glyco_hydro_28 PF00295.17 KNZ76189.1 - 9e-36 123.6 3.8 1.2e-35 123.2 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KNZ76189.1 - 3.4 7.5 19.5 3.7 7.4 16.4 2.6 1 1 1 2 2 2 0 Right handed beta helix region UQ_con PF00179.26 KNZ76190.1 - 1.6e-44 151.0 0.1 1.8e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNZ76190.1 - 0.0039 16.9 0.0 0.0093 15.7 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 KNZ76190.1 - 0.077 13.3 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain EMP24_GP25L PF01105.24 KNZ76191.1 - 1.7e-42 145.4 0.0 2e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNase_PH PF01138.21 KNZ76193.1 - 5.5e-22 78.7 0.0 9.3e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M24 PF00557.24 KNZ76194.1 - 7.9e-56 189.0 0.0 1e-55 188.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KNZ76194.1 - 7.2e-17 61.3 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Use1 PF09753.9 KNZ76195.1 - 1.3e-18 67.6 0.9 1.4e-16 60.9 0.1 2.4 2 1 0 2 2 2 2 Membrane fusion protein Use1 DUF3671 PF12420.8 KNZ76195.1 - 4.3 7.5 5.6 7.8 6.6 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function TPR_11 PF13414.6 KNZ76196.1 - 9.8e-09 34.8 0.0 0.00022 20.8 0.0 2.6 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 KNZ76196.1 - 1.3e-08 35.3 1.1 1.3e-05 25.8 1.2 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat zf-CCCH_4 PF18044.1 KNZ76196.1 - 4.8e-08 32.6 8.2 0.0011 18.7 0.4 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger TPR_17 PF13431.6 KNZ76196.1 - 8.8e-07 28.9 0.0 0.54 10.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ76196.1 - 3.7e-06 26.6 0.1 0.072 13.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ76196.1 - 5.5e-06 26.4 0.3 1.1e-05 25.5 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ76196.1 - 6.8e-06 25.7 0.0 0.35 10.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-CCCH_3 PF15663.5 KNZ76196.1 - 0.00082 19.6 1.0 0.43 10.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger containing family TPR_14 PF13428.6 KNZ76196.1 - 0.0091 16.7 0.1 0.03 15.1 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ76196.1 - 0.0092 16.5 0.4 0.16 12.5 0.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 KNZ76196.1 - 0.0099 16.3 9.2 0.34 11.4 3.3 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 KNZ76196.1 - 2.6 8.2 11.5 4.6 7.4 4.2 2.8 2 1 0 2 2 2 0 Zinc finger domain Torus PF16131.5 KNZ76196.1 - 9 7.0 10.2 2.3 9.0 0.8 3.0 2 1 1 3 3 3 0 Torus domain zf-CCCH PF00642.24 KNZ76196.1 - 9.7 6.2 9.2 8.5 6.4 2.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Prenyltrans PF00432.21 KNZ76197.1 - 2.1e-38 129.7 7.3 3.9e-09 36.1 0.4 6.4 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 KNZ76197.1 - 0.00023 20.3 0.0 0.74 8.9 0.0 2.5 3 0 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Ribosomal_S10 PF00338.22 KNZ76198.1 - 1.8e-28 98.6 0.0 3.1e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FANCI_S1-cap PF14674.6 KNZ76198.1 - 0.12 12.5 0.2 0.3 11.2 0.2 1.7 1 0 0 1 1 1 0 FANCI solenoid 1 cap Ribosomal_L23 PF00276.20 KNZ76199.1 - 8.4e-17 61.3 2.5 4e-16 59.2 2.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L23 PARP_regulatory PF01358.18 KNZ76199.1 - 0.054 12.4 0.2 0.063 12.2 0.2 1.1 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Nop53 PF07767.11 KNZ76200.1 - 3.8e-100 336.1 23.1 4.5e-100 335.8 23.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) pRN1_helical PF13010.6 KNZ76200.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.2 2 1 0 2 2 2 0 Primase helical domain Birna_RdRp PF04197.12 KNZ76200.1 - 0.25 9.6 3.8 0.34 9.2 3.8 1.2 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) CBF PF03914.17 KNZ76201.1 - 2.5e-39 135.0 0.1 2.5e-39 135.0 0.1 3.0 3 1 0 3 3 3 1 CBF/Mak21 family Aminotran_1_2 PF00155.21 KNZ76202.1 - 2.5e-42 145.4 0.0 3.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II TFIIIC_sub6 PF10419.9 KNZ76203.1 - 1.2e-12 47.5 0.1 7e-12 45.1 0.1 2.0 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain TT_ORF2 PF02957.15 KNZ76203.1 - 0.24 12.3 4.6 9.9 7.1 2.2 2.2 2 0 0 2 2 2 0 TT viral ORF2 FtsJ PF01728.19 KNZ76204.1 - 3.3e-16 59.9 0.0 5.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Macoilin PF09726.9 KNZ76204.1 - 0.96 7.9 5.3 1.2 7.7 5.3 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 KNZ76204.1 - 3.1 6.7 6.0 4.7 6.1 6.0 1.1 1 0 0 1 1 1 0 Mitoguardin Ndc1_Nup PF09531.10 KNZ76204.1 - 6.6 5.3 9.5 8.5 4.9 9.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RXT2_N PF08595.11 KNZ76205.1 - 0.16 12.0 2.2 0.23 11.5 2.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PPARgamma_N PF12577.8 KNZ76206.1 - 0.021 15.5 0.8 0.36 11.5 0.0 2.2 2 0 0 2 2 2 0 PPAR gamma N-terminal region RXT2_N PF08595.11 KNZ76206.1 - 0.032 14.3 2.2 0.04 13.9 2.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal BAR_2 PF10455.9 KNZ76209.1 - 7.8e-12 44.9 0.7 9.6e-12 44.6 0.7 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KNZ76209.1 - 0.0029 17.3 0.3 0.0034 17.1 0.3 1.1 1 0 0 1 1 1 1 BAR domain PAP_fibrillin PF04755.12 KNZ76209.1 - 0.023 14.6 0.1 0.029 14.3 0.1 1.1 1 0 0 1 1 1 0 PAP_fibrillin DUF4451 PF14616.6 KNZ76210.1 - 6.8e-15 55.4 0.5 7.9e-15 55.1 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Put_DNA-bind_N PF06971.13 KNZ76211.1 - 0.12 12.5 0.1 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus M64_N PF16217.5 KNZ76211.1 - 0.13 11.8 0.1 0.33 10.5 0.1 1.5 1 1 0 1 1 1 0 Peptidase M64 N-terminus rOmpB PF12334.8 KNZ76212.1 - 0.0032 17.0 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Rickettsia outer membrane protein B Arabinose_bd PF12625.7 KNZ76212.1 - 0.027 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term DUF4449 PF14613.6 KNZ76213.1 - 1.5e-17 64.2 0.0 2.1e-15 57.2 0.0 2.9 1 1 0 2 2 2 1 Protein of unknown function (DUF4449) Apolipoprotein PF01442.18 KNZ76213.1 - 0.029 14.2 14.5 6.6 6.6 0.1 4.3 3 1 1 4 4 4 0 Apolipoprotein A1/A4/E domain Spectrin PF00435.21 KNZ76213.1 - 1.1 9.8 10.9 0.13 12.8 0.4 3.7 4 0 0 4 4 4 0 Spectrin repeat Med15 PF09606.10 KNZ76213.1 - 2.9 6.5 5.7 4.5 5.8 5.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mago_nashi PF02792.14 KNZ76214.1 - 3e-76 254.3 0.4 3.4e-76 254.2 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein CENP-T_C PF15511.6 KNZ76215.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KNZ76215.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KNZ76215.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KNZ76215.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ76215.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KNZ76215.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit FtsJ PF01728.19 KNZ76216.1 - 1.1e-44 152.7 0.0 1.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase MFS_1 PF07690.16 KNZ76217.1 - 1.8e-16 60.0 48.1 9.6e-15 54.3 33.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3337 PF11816.8 KNZ76218.1 - 2.8e-35 121.7 0.0 5.3e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KNZ76218.1 - 6.5e-22 77.4 15.6 9.8e-07 29.4 0.1 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KNZ76218.1 - 0.00077 18.2 1.9 0.023 13.4 0.0 3.1 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ76218.1 - 0.0029 16.6 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAWUL PF16207.5 KNZ76218.1 - 0.0058 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like ANAPC4_WD40 PF12894.7 KNZ76218.1 - 0.017 15.4 0.0 0.33 11.3 0.1 2.8 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 KNZ76218.1 - 0.19 10.6 1.7 3.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PWWP PF00855.17 KNZ76223.1 - 6.6e-18 64.9 0.5 1.4e-17 63.9 0.5 1.7 1 1 0 1 1 1 1 PWWP domain Med26 PF08711.11 KNZ76223.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4551 PF15087.6 KNZ76223.1 - 0.29 9.9 3.4 0.39 9.5 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MAJIN PF15077.6 KNZ76223.1 - 4.6 7.0 8.0 8.8 6.0 8.0 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Ricin_B_lectin PF00652.22 KNZ76224.1 - 1.7e-18 67.1 0.8 2.8e-18 66.4 0.8 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KNZ76224.1 - 1e-12 48.6 10.4 7.5e-07 29.8 0.4 3.0 2 2 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Pkr1 PF08636.10 KNZ76225.1 - 2.7 8.2 11.8 0.15 12.3 3.3 2.9 1 1 2 3 3 3 0 ER protein Pkr1 Asp PF00026.23 KNZ76226.1 - 1.7e-41 142.7 0.2 6.3e-41 140.8 0.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ76226.1 - 2.2e-07 31.3 0.1 5.5e-05 23.5 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KNZ76226.1 - 0.0046 16.7 0.0 0.033 14.0 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KNZ76226.1 - 0.09 13.4 0.5 3.2 8.4 0.0 2.9 3 0 0 3 3 3 0 Aspartyl protease Iso_dh PF00180.20 KNZ76227.1 - 5.9e-83 278.9 0.0 6.8e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LIP1 PF15904.5 KNZ76228.1 - 0.062 13.6 2.7 0.22 11.9 0.2 2.8 3 0 0 3 3 3 0 LKB1 serine/threonine kinase interacting protein 1 DUF2618 PF10940.8 KNZ76228.1 - 0.18 11.6 0.7 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) Tcf25 PF04910.14 KNZ76229.1 - 6.4e-84 282.0 0.0 2e-83 280.4 0.0 1.7 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TPR_12 PF13424.6 KNZ76229.1 - 0.026 14.8 0.1 0.091 13.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ76229.1 - 0.15 12.7 0.3 50 4.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_polI_A34 PF08208.11 KNZ76229.1 - 0.74 9.9 14.5 0.68 10.0 11.7 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 TPR_14 PF13428.6 KNZ76229.1 - 0.87 10.6 5.9 1.3 10.0 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 KNZ76229.1 - 8.7 6.1 13.6 1.3 8.8 8.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Sugar_tr PF00083.24 KNZ76230.1 - 1.2e-39 136.5 20.4 4.3e-29 101.7 13.3 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter DUF3808 PF10300.9 KNZ76231.1 - 2.2e-59 201.5 0.0 5.9e-36 124.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3808) TPR_19 PF14559.6 KNZ76231.1 - 3.2e-08 34.0 1.9 3.9e-06 27.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ76231.1 - 7e-06 25.8 6.0 0.73 10.1 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ76231.1 - 1.1e-05 25.2 1.5 1.6 9.1 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ76231.1 - 0.00012 22.7 3.4 0.05 14.3 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ76231.1 - 0.00025 21.6 4.7 10 7.2 0.1 4.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ76231.1 - 0.0009 19.7 2.5 11 6.9 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ76231.1 - 0.0014 18.4 0.4 2 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ76231.1 - 0.0019 18.4 5.9 0.84 10.0 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat Dak1 PF02733.17 KNZ76231.1 - 0.006 15.5 1.1 0.0094 14.9 1.1 1.2 1 0 0 1 1 1 1 Dak1 domain ANAPC3 PF12895.7 KNZ76231.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.6 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP-synt_G PF04718.15 KNZ76232.1 - 0.12 13.2 0.0 0.18 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit Kdo PF06293.14 KNZ76234.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Amidohydro_3 PF07969.11 KNZ76236.1 - 8.3e-15 55.2 0.6 7.6e-07 29.0 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 KNZ76236.1 - 8.8e-14 51.6 0.2 2e-09 37.2 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family Gtr1_RagA PF04670.12 KNZ76237.1 - 0.057 12.8 3.4 1.2 8.5 0.1 2.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF5082 PF16888.5 KNZ76237.1 - 0.08 13.2 6.9 6.1 7.1 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) LPP PF04728.13 KNZ76237.1 - 5.2 7.5 11.0 3.6 8.0 0.4 4.6 3 1 0 3 3 3 0 Lipoprotein leucine-zipper 2OG-FeII_Oxy PF03171.20 KNZ76238.1 - 1e-17 64.5 0.0 5.2e-17 62.2 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KNZ76238.1 - 2.9e-17 63.5 0.0 6.6e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_hydro_16 PF00722.21 KNZ76239.1 - 6.1e-18 64.9 0.0 1.1e-17 64.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 KNZ76240.1 - 3.1e-54 183.9 0.4 3.1e-54 183.9 0.4 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KNZ76240.1 - 3e-06 27.3 0.0 5.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KNZ76240.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 CI-B14_5a PF07347.12 KNZ76240.1 - 0.095 12.6 0.2 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) ADH_zinc_N PF00107.26 KNZ76241.1 - 8.7e-21 74.3 0.5 1.8e-20 73.2 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ76241.1 - 2.1e-12 48.3 0.0 3.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ76241.1 - 3.8e-06 26.7 0.4 2.4e-05 24.2 0.0 2.5 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain MitMem_reg PF13012.6 KNZ76242.1 - 7.6e-35 119.7 0.6 1.2e-34 119.1 0.6 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 KNZ76242.1 - 5.6e-29 100.5 0.5 1.3e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease zf-CCHC PF00098.23 KNZ76243.1 - 7.5e-34 114.3 46.7 2.5e-08 33.6 2.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ76243.1 - 0.00015 21.6 29.1 0.17 11.9 0.2 5.3 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 KNZ76243.1 - 0.00052 19.7 28.9 0.13 12.0 1.6 5.5 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_5 PF14787.6 KNZ76243.1 - 0.0056 16.4 19.7 0.018 14.8 0.4 5.3 4 1 1 5 5 5 2 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 KNZ76243.1 - 0.086 12.7 31.5 0.16 11.8 6.0 5.0 4 1 1 5 5 5 0 Zinc knuckle Clusterin PF01093.17 KNZ76243.1 - 0.28 10.2 1.5 0.33 10.0 1.5 1.1 1 0 0 1 1 1 0 Clusterin Peptidase_M43 PF05572.13 KNZ76244.1 - 2.8e-15 56.6 0.0 6e-15 55.5 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KNZ76244.1 - 6.5e-05 23.2 0.1 9.7e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KNZ76244.1 - 0.00089 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KNZ76244.1 - 0.029 14.0 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KNZ76244.1 - 0.04 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 KNZ76244.1 - 0.082 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M10 PF00413.24 KNZ76244.1 - 0.088 12.7 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Ctr PF04145.15 KNZ76245.1 - 2.5e-19 70.3 0.3 3.5e-19 69.9 0.3 1.2 1 0 0 1 1 1 1 Ctr copper transporter family ATP-synt_Eps PF04627.13 KNZ76246.1 - 1e-17 63.8 1.3 1.5e-17 63.3 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.22 KNZ76247.1 - 5.9e-51 172.3 0.0 6.8e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ76247.1 - 2.8e-29 101.8 0.0 3.8e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ76247.1 - 1.6e-12 47.2 0.0 1.9e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ76247.1 - 9e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNZ76247.1 - 0.00016 21.3 0.0 0.0034 17.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KNZ76247.1 - 0.058 13.3 0.0 4.8 7.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 KNZ76247.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Dynamin family DSPc PF00782.20 KNZ76248.1 - 3.7e-23 81.8 0.0 4.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KNZ76248.1 - 0.0021 18.3 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 KNZ76248.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DEAD PF00270.29 KNZ76249.1 - 1.1e-21 77.3 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ76249.1 - 0.0058 17.0 0.4 1 9.7 0.0 3.1 3 1 1 4 4 4 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KNZ76249.1 - 0.021 14.1 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MFS_1 PF07690.16 KNZ76250.1 - 4.4e-26 91.7 69.6 6.5e-18 64.8 40.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KNZ76250.1 - 6.9 4.8 13.2 12 4.0 13.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Fibrillarin PF01269.17 KNZ76251.1 - 1.8e-106 354.3 0.0 2.2e-106 354.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KNZ76251.1 - 0.00027 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KNZ76251.1 - 0.0082 15.9 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KNZ76251.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KNZ76251.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PMT PF02366.18 KNZ76252.1 - 6.2e-84 281.4 18.3 6.2e-84 281.4 18.3 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KNZ76252.1 - 4.3e-48 163.6 11.4 1.1e-41 142.6 3.6 3.1 3 1 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KNZ76252.1 - 5.6e-27 94.8 0.4 8.8e-27 94.1 0.4 1.2 1 0 0 1 1 1 1 MIR domain DUF4969 PF16339.5 KNZ76252.1 - 0.11 12.8 0.7 0.28 11.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) PMT_2 PF13231.6 KNZ76252.1 - 3.6 7.8 22.1 0.09 13.0 12.0 2.6 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase VPS28 PF03997.12 KNZ76254.1 - 3.2e-70 235.7 0.0 3.7e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein adh_short PF00106.25 KNZ76255.1 - 4.6e-33 114.3 0.0 5.9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ76255.1 - 2.5e-15 56.7 0.0 3.1e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ76255.1 - 4.1e-08 33.4 0.0 7.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ76255.1 - 1.3e-05 24.8 0.1 7.1e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ76255.1 - 0.0096 15.8 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding SP24 PF16504.5 KNZ76255.1 - 0.029 14.4 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Putative virion membrane protein of plant and insect virus Jacalin PF01419.17 KNZ76256.1 - 1.4e-05 25.1 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.23 KNZ76256.1 - 0.00016 21.3 0.6 0.00029 20.5 0.6 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-RVT PF13966.6 KNZ76258.1 - 0.0079 16.9 0.9 0.035 14.8 0.9 2.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase PIF1 PF05970.14 KNZ76259.1 - 1.8e-60 205.1 0.0 1.9e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76259.1 - 5.2e-06 26.3 0.0 6.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ76259.1 - 0.054 13.2 0.1 0.13 12.0 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KNZ76259.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Torsin RNA_helicase PF00910.22 KNZ76259.1 - 0.14 12.6 0.1 0.64 10.4 0.1 2.0 1 1 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 KNZ76261.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ76261.1 - 0.00048 20.1 0.1 0.0036 17.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 KNZ76261.1 - 0.039 13.3 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Septin PF00735.18 KNZ76261.1 - 0.04 13.2 0.3 0.17 11.1 0.1 1.9 1 1 1 2 2 2 0 Septin DUF815 PF05673.13 KNZ76261.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KNZ76261.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ76261.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 KNZ76261.1 - 0.24 11.4 1.2 4.6 7.3 0.5 2.3 1 1 1 2 2 2 0 Dynamin family G-alpha PF00503.20 KNZ76262.1 - 4.6e-05 22.8 0.1 0.0013 17.9 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KNZ76262.1 - 9.5e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KNZ76262.1 - 0.0019 17.7 0.0 0.0055 16.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 KNZ76262.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KNZ76262.1 - 0.021 14.3 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ATP_bind_1 PF03029.17 KNZ76262.1 - 0.025 14.4 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KNZ76262.1 - 0.084 13.3 0.0 0.3 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 KNZ76262.1 - 0.085 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein GTP_EFTU PF00009.27 KNZ76262.1 - 0.093 12.3 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 KNZ76262.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Arrestin_C PF02752.22 KNZ76264.1 - 0.00033 21.1 0.0 0.01 16.3 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KNZ76264.1 - 0.00079 19.2 0.0 0.0074 16.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 KNZ76264.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HSF_DNA-bind PF00447.17 KNZ76265.1 - 4.2e-29 101.0 0.3 7.9e-29 100.1 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding DUF2780 PF11075.8 KNZ76265.1 - 0.01 16.0 0.7 0.01 16.0 0.7 2.1 2 1 1 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) zf-C4H2 PF10146.9 KNZ76266.1 - 0.63 10.3 10.6 1 9.6 0.1 2.4 3 0 0 3 3 3 0 Zinc finger-containing protein AT_hook PF02178.19 KNZ76266.1 - 6.5 7.0 8.3 15 5.9 8.3 1.7 1 0 0 1 1 1 0 AT hook motif Cyclin_N PF00134.23 KNZ76267.1 - 3.6e-11 42.9 0.0 5.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KNZ76267.1 - 4.4e-08 33.7 0.0 8.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin IML1 PF12257.8 KNZ76268.1 - 3.3e-112 374.3 0.0 4.5e-112 373.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KNZ76268.1 - 1.7e-19 69.6 0.1 3.7e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TBD PF12845.7 KNZ76268.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 TBD domain Acetyltransf_1 PF00583.25 KNZ76269.1 - 1.3e-08 35.1 0.0 1.7e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ76269.1 - 4.5e-07 30.2 0.1 9e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ76269.1 - 3.6e-06 26.9 0.0 5.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ76269.1 - 9.8e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KNZ76269.1 - 0.0046 17.0 0.3 0.0084 16.2 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KNZ76269.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAS_10 PF13596.6 KNZ76270.1 - 0.0029 18.2 0.0 0.0047 17.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain F-box PF00646.33 KNZ76271.1 - 0.022 14.6 0.5 0.069 13.1 0.5 1.9 1 0 0 1 1 1 0 F-box domain Pyr_redox_3 PF13738.6 KNZ76272.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4195 PF13836.6 KNZ76273.1 - 0.014 15.5 1.9 0.35 11.0 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) Peptidase_S28 PF05577.12 KNZ76274.1 - 2.2e-46 158.6 0.1 1.6e-38 132.7 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 MFMR PF07777.11 KNZ76274.1 - 0.0033 17.9 1.1 1.2 9.7 0.0 2.7 2 0 0 2 2 2 2 G-box binding protein MFMR Peptidase_S9 PF00326.21 KNZ76274.1 - 0.069 12.6 1.1 0.16 11.4 1.0 1.6 1 1 1 2 2 2 0 Prolyl oligopeptidase family UCH PF00443.29 KNZ76275.1 - 8e-37 127.1 0.0 1.5e-36 126.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ76275.1 - 0.074 12.6 0.1 0.34 10.4 0.1 2.0 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase p450 PF00067.22 KNZ76276.1 - 1.8e-40 139.1 0.0 4.2e-26 91.7 0.1 2.9 2 1 0 2 2 2 2 Cytochrome P450 zf-C2H2_jaz PF12171.8 KNZ76277.1 - 0.035 14.4 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ76277.1 - 0.068 13.6 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KNZ76277.1 - 0.087 13.2 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CTU2 PF10288.9 KNZ76277.1 - 1.2 9.4 12.1 0.21 11.9 3.4 2.7 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 APH PF01636.23 KNZ76278.1 - 8.1e-10 39.0 0.0 2.1e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Phage_gp49_66 PF13876.6 KNZ76278.1 - 0.19 12.1 0.1 0.32 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family APH PF01636.23 KNZ76279.1 - 2.5e-12 47.2 0.0 3.7e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KNZ76279.1 - 3.6e-05 22.8 0.0 0.046 12.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) DNA_pol_A_exo1 PF01612.20 KNZ76280.1 - 5.1e-05 23.1 0.0 6.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease RVP_2 PF08284.11 KNZ76281.1 - 0.0059 16.4 0.2 0.0067 16.2 0.2 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Allexi_40kDa PF05549.11 KNZ76282.1 - 0.0032 17.0 0.2 0.004 16.7 0.2 1.1 1 0 0 1 1 1 1 Allexivirus 40kDa protein DUF4396 PF14342.6 KNZ76282.1 - 0.021 15.2 1.8 0.044 14.2 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) tRNA-synt_His PF13393.6 KNZ76282.1 - 0.16 11.2 0.6 0.2 10.9 0.6 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF5340 PF17275.2 KNZ76283.1 - 0.014 15.6 1.0 0.15 12.2 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5340) DUF4164 PF13747.6 KNZ76283.1 - 0.015 15.5 0.9 0.015 15.5 0.9 2.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4164) MRPL52 PF18699.1 KNZ76283.1 - 0.023 14.9 2.5 3.2 8.0 0.1 2.9 2 1 1 3 3 3 0 Mitoribosomal protein mL52 Vfa1 PF08432.10 KNZ76283.1 - 0.11 12.8 5.4 0.17 12.2 5.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 WD40 PF00400.32 KNZ76284.1 - 1.1e-07 32.4 0.2 0.028 15.3 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box PF00646.33 KNZ76284.1 - 2.3e-06 27.3 1.2 7.6e-06 25.7 0.1 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KNZ76284.1 - 8.7e-06 25.5 3.0 3.7e-05 23.5 0.3 2.5 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 KNZ76284.1 - 0.0014 18.9 0.0 0.85 10.0 0.0 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5596 PF18082.1 KNZ76285.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) p450 PF00067.22 KNZ76289.1 - 1.5e-56 192.1 0.0 1.3e-39 136.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KNZ76290.1 - 2.4e-68 231.0 0.0 3e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp_protease_2 PF13650.6 KNZ76291.1 - 0.0003 21.4 0.0 0.0003 21.4 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ76291.1 - 0.018 15.6 0.0 0.018 15.6 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KNZ76291.1 - 0.069 12.9 0.0 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease WD40 PF00400.32 KNZ76294.1 - 2.8e-06 27.9 0.1 0.00013 22.7 0.1 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ76294.1 - 0.021 15.1 0.0 0.27 11.6 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain tRNA-synt_2c PF01411.19 KNZ76295.1 - 6.7e-26 90.9 0.3 1.3e-25 89.9 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KNZ76295.1 - 2e-16 59.8 0.0 6.7e-16 58.1 0.0 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KNZ76295.1 - 0.38 11.2 3.8 0.15 12.5 0.5 2.0 2 0 0 2 2 2 0 DHHA1 domain Herpes_Helicase PF02689.14 KNZ76296.1 - 6.8e-05 21.0 0.0 7.1e-05 21.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ76296.1 - 0.063 13.1 0.3 0.29 11.0 0.2 2.1 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Usp PF00582.26 KNZ76299.1 - 2.7e-07 31.2 1.1 8.3e-07 29.6 1.1 1.7 1 1 0 1 1 1 1 Universal stress protein family ADPrib_exo_Tox PF03496.14 KNZ76299.1 - 0.088 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme Glyco_hydro_47 PF01532.20 KNZ76300.1 - 1.5e-30 106.5 0.0 2e-23 83.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_31 PF01055.26 KNZ76301.1 - 2.6e-21 76.4 0.2 1.6e-19 70.4 0.2 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KNZ76301.1 - 2.4e-12 47.0 0.1 4.4e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 Galactose mutarotase-like THF_DHG_CYH PF00763.23 KNZ76301.1 - 0.12 12.7 0.3 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TFIIA PF03153.13 KNZ76302.1 - 0.012 15.6 7.1 0.013 15.5 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIF1 PF05970.14 KNZ76303.1 - 1.6e-106 356.6 0.0 1.9e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76303.1 - 1.1e-07 31.8 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ76303.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ76303.1 - 0.037 14.4 0.0 0.078 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ76303.1 - 0.094 12.4 0.1 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Nop53 PF07767.11 KNZ76304.1 - 0.19 11.1 35.2 0.34 10.3 35.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Dor1 PF04124.12 KNZ76305.1 - 4.2e-43 147.3 0.0 2.2e-42 144.9 0.0 1.9 1 1 0 1 1 1 1 Dor1-like family Baculo_LEF-11 PF06385.12 KNZ76305.1 - 0.064 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Baculovirus LEF-11 protein Baculo_PEP_C PF04513.12 KNZ76305.1 - 0.11 12.5 0.4 0.7 9.9 0.6 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps51 PF08700.11 KNZ76305.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Vps51/Vps67 G-alpha PF00503.20 KNZ76308.1 - 1.4e-98 330.4 0.0 6.3e-98 328.2 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ76308.1 - 1.6e-11 44.0 1.8 4.3e-08 32.8 1.7 3.2 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 KNZ76308.1 - 0.0088 16.3 0.6 2.6 8.3 0.1 3.1 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KNZ76308.1 - 0.026 14.2 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 KNZ76308.1 - 0.099 12.2 0.1 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 KNZ76308.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ribonuc_L-PSP PF01042.21 KNZ76309.1 - 2.5e-42 143.7 0.0 2.8e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Proteasome PF00227.26 KNZ76310.1 - 2.5e-56 190.2 0.0 3e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Inositol_P PF00459.25 KNZ76311.1 - 7e-67 225.8 0.0 7.9e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Sugar_tr PF00083.24 KNZ76312.1 - 3.9e-116 388.6 6.9 2.2e-115 386.1 6.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ76312.1 - 8e-18 64.5 27.6 8.8e-15 54.5 7.9 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DASH_Ask1 PF08655.10 KNZ76314.1 - 1.1e-24 86.0 0.2 2.1e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 TIP49 PF06068.13 KNZ76315.1 - 2e-157 523.9 0.6 3e-157 523.3 0.6 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KNZ76315.1 - 9.7e-21 73.7 0.7 6.3e-20 71.1 1.1 2.2 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 KNZ76315.1 - 1.2e-08 35.5 2.8 1.2e-05 25.8 0.0 3.4 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNZ76315.1 - 4.6e-06 26.5 0.2 0.0068 16.2 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 KNZ76315.1 - 3.5e-05 23.3 0.4 8.3e-05 22.0 0.4 1.6 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KNZ76315.1 - 4.6e-05 23.9 0.1 0.00024 21.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KNZ76315.1 - 0.0011 18.5 1.5 0.028 13.8 0.4 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KNZ76315.1 - 0.0053 17.0 0.0 0.41 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KNZ76315.1 - 0.0064 16.1 0.3 0.021 14.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KNZ76315.1 - 0.01 15.9 1.6 7.4 6.6 0.0 3.4 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KNZ76315.1 - 0.064 13.6 6.7 0.085 13.2 1.1 3.1 2 1 0 2 2 2 0 AAA domain FRG2 PF15315.6 KNZ76315.1 - 0.073 13.3 0.2 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 TFIID-31kDa PF02291.15 KNZ76315.1 - 0.089 12.9 0.4 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AAA_7 PF12775.7 KNZ76315.1 - 0.15 11.6 0.4 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynactin PF12455.8 KNZ76316.1 - 2.2e-89 299.5 2.5 2.2e-89 299.5 2.5 3.7 4 2 1 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 KNZ76316.1 - 3.2e-21 75.1 0.6 1.1e-20 73.4 0.6 1.8 2 0 0 2 2 2 1 CAP-Gly domain TMF_DNA_bd PF12329.8 KNZ76316.1 - 0.00086 19.3 2.0 0.00086 19.3 2.0 9.7 8 3 2 10 10 10 3 TATA element modulatory factor 1 DNA binding TraF_2 PF13729.6 KNZ76316.1 - 2.4 7.5 6.3 16 4.8 0.5 2.7 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein Raptor_N PF14538.6 KNZ76317.1 - 1.1e-61 207.1 0.0 8.2e-61 204.3 0.0 2.2 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KNZ76317.1 - 1.2e-05 25.9 8.4 0.057 14.3 0.2 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat HEAT PF02985.22 KNZ76317.1 - 1.4e-05 24.9 0.8 0.0041 17.2 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KNZ76317.1 - 0.00018 21.8 0.1 0.00091 19.6 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 KNZ76317.1 - 0.0014 19.1 0.1 0.03 14.9 0.1 2.9 2 0 0 2 2 2 1 HEAT-like repeat Cnd1 PF12717.7 KNZ76317.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 KNZ76317.1 - 0.032 13.8 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 Dus PF01207.17 KNZ76318.1 - 1.9e-52 178.3 0.0 3.7e-52 177.4 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) MDM1 PF15501.6 KNZ76318.1 - 0.14 11.3 0.7 0.17 11.0 0.7 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 CPSase_L_D2 PF02786.17 KNZ76319.1 - 1.1e-70 237.4 0.0 1.7e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KNZ76319.1 - 1.3e-46 157.7 0.3 4.8e-46 155.8 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KNZ76319.1 - 1.9e-30 105.1 0.0 3.5e-28 97.9 0.0 2.9 2 1 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KNZ76319.1 - 5.9e-16 58.1 1.8 1.3e-15 57.0 1.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KNZ76319.1 - 6.9e-07 29.0 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 KNZ76319.1 - 3.5e-06 26.7 0.3 6.7e-05 22.6 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like Ntox43 PF15537.6 KNZ76319.1 - 0.0024 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial toxin 43 GARS_A PF01071.19 KNZ76319.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_3 PF13437.6 KNZ76319.1 - 0.01 16.5 0.2 6.9 7.4 0.1 2.8 2 0 0 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.6 KNZ76319.1 - 0.01 15.8 0.5 0.24 11.4 0.3 2.8 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 KNZ76319.1 - 0.043 13.0 0.4 2.2 7.4 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 KNZ76319.1 - 0.044 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 KNZ76319.1 - 0.048 12.9 0.0 0.097 11.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Poly_export PF02563.16 KNZ76319.1 - 0.15 12.3 0.0 0.66 10.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein O-FucT PF10250.9 KNZ76320.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Calpain_inhib PF00748.19 KNZ76321.1 - 0.037 14.5 1.6 0.046 14.2 1.4 1.4 1 1 0 1 1 1 0 Calpain inhibitor CART PF06373.11 KNZ76321.1 - 0.059 13.6 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Adaptin_N PF01602.20 KNZ76323.1 - 1.9e-109 366.6 0.2 2.4e-109 366.3 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KNZ76323.1 - 1.8e-11 44.4 3.5 3.4e-07 30.5 0.0 3.1 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ76323.1 - 6.4e-08 32.9 3.2 0.012 16.0 0.0 4.1 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 KNZ76323.1 - 8.1e-08 31.9 3.9 0.56 10.6 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat RTP1_C1 PF10363.9 KNZ76323.1 - 5.2e-05 23.4 2.7 0.039 14.1 0.0 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 KNZ76323.1 - 0.0036 17.4 0.5 1.3 9.2 0.0 3.7 2 1 1 3 3 3 1 V-ATPase subunit H Cnd3 PF12719.7 KNZ76323.1 - 0.011 14.9 0.1 1.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KNZ76323.1 - 0.013 16.0 3.3 2.5 8.7 0.0 5.4 6 1 2 8 8 8 0 HEAT-like repeat MMS19_N PF14500.6 KNZ76323.1 - 0.068 12.7 0.1 8.2 5.9 0.0 2.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Nipped-B_C PF12830.7 KNZ76323.1 - 0.079 12.9 1.4 31 4.4 0.1 3.5 3 1 1 4 4 4 0 Sister chromatid cohesion C-terminus Pkinase PF00069.25 KNZ76324.1 - 2.2e-69 233.8 0.0 3.1e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76324.1 - 4.1e-50 170.5 0.0 5.8e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ76324.1 - 1.7e-05 23.8 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KNZ76324.1 - 0.00022 20.7 0.0 0.0035 16.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KNZ76324.1 - 0.0024 16.9 0.0 0.089 11.7 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain DUF1241 PF06840.11 KNZ76324.1 - 0.0039 16.9 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) ORC6 PF05460.13 KNZ76324.1 - 0.056 12.7 3.3 0.086 12.1 3.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2076 PF09849.9 KNZ76324.1 - 0.16 12.0 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cation_efflux PF01545.21 KNZ76325.1 - 5.4e-20 72.0 7.2 6.7e-20 71.7 7.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KNZ76325.1 - 1.4e-12 47.5 0.7 2.2e-12 46.9 0.1 1.6 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter CcmB PF03379.13 KNZ76327.1 - 0.0012 18.3 0.1 0.0016 18.0 0.1 1.1 1 0 0 1 1 1 1 CcmB protein APH PF01636.23 KNZ76328.1 - 0.00035 20.6 1.8 0.012 15.5 1.7 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ76328.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pyridox_oxase_2 PF12766.7 KNZ76331.1 - 1.8e-22 79.8 0.0 3.4e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 KNZ76331.1 - 0.0049 17.0 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Homeodomain PF00046.29 KNZ76332.1 - 5.6e-18 64.5 2.6 9.3e-18 63.8 2.6 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KNZ76332.1 - 0.0099 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain VASt PF16016.5 KNZ76333.1 - 1.5e-37 129.3 0.0 3.1e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 KNZ76333.1 - 5.2e-23 81.1 0.0 1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 GRAM domain NAD_binding_8 PF13450.6 KNZ76334.1 - 5.3e-09 36.2 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 KNZ76334.1 - 1.1e-06 27.4 0.1 0.004 15.6 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ76334.1 - 8.5e-06 25.2 0.0 0.0074 15.6 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ76334.1 - 0.0029 17.6 0.0 0.027 14.4 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KNZ76334.1 - 0.0074 15.5 0.0 0.44 9.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KNZ76334.1 - 0.029 14.0 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ76334.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.25 KNZ76335.1 - 2.3e-61 207.5 0.0 4.1e-36 124.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76335.1 - 2.9e-26 92.3 0.0 3.6e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 KNZ76335.1 - 0.00012 22.7 5.1 0.00097 19.8 5.1 2.8 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 KNZ76335.1 - 0.0027 17.4 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 PX PF00787.24 KNZ76335.1 - 0.0057 16.6 0.0 0.038 14.0 0.1 2.3 2 0 0 2 2 2 1 PX domain Kdo PF06293.14 KNZ76335.1 - 0.054 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ76335.1 - 0.058 13.3 0.3 6.4 6.6 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CorA PF01544.18 KNZ76336.1 - 3.3e-34 118.5 7.8 4.4e-30 105.0 5.0 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein RNA_pol_L_2 PF13656.6 KNZ76336.1 - 0.072 12.9 0.2 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF5360 PF17314.2 KNZ76336.1 - 0.08 13.0 1.5 0.14 12.2 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5360) Pga1 PF10333.9 KNZ76337.1 - 0.035 14.0 7.3 0.41 10.5 7.3 2.1 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator RCC1 PF00415.18 KNZ76338.1 - 1.8e-24 86.1 18.5 6.4e-06 26.7 0.5 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNZ76338.1 - 6.4e-09 35.4 24.9 0.0023 17.7 0.1 6.9 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat PfkB PF00294.24 KNZ76339.1 - 1.8e-69 234.4 1.8 2.1e-69 234.1 1.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Calreticulin PF00262.18 KNZ76341.1 - 7.6e-161 535.0 10.3 1.1e-160 534.5 10.3 1.2 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.27 KNZ76341.1 - 3.8e-45 153.8 0.0 5.9e-45 153.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KNZ76341.1 - 4.9e-38 130.5 7.6 4.9e-38 130.5 7.6 1.8 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KNZ76341.1 - 5.1e-23 81.1 0.0 1.3e-22 79.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KNZ76341.1 - 7.5e-22 77.2 0.0 1.8e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ76341.1 - 8.3e-10 38.9 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KNZ76341.1 - 4.3e-06 26.7 0.1 3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KNZ76341.1 - 4e-05 23.7 0.2 7.7e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KNZ76341.1 - 0.0062 16.0 0.1 0.022 14.2 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Prefoldin_2 PF01920.20 KNZ76342.1 - 2.4e-15 56.4 9.2 3.4e-15 55.9 9.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Ax_dynein_light PF10211.9 KNZ76342.1 - 0.0032 17.4 2.8 0.0043 17.0 2.3 1.4 1 1 0 1 1 1 1 Axonemal dynein light chain Seryl_tRNA_N PF02403.22 KNZ76342.1 - 0.079 13.2 7.1 0.18 12.1 7.1 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rib_5-P_isom_A PF06026.14 KNZ76342.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) NPV_P10 PF05531.12 KNZ76342.1 - 0.12 12.9 0.6 0.12 12.9 0.6 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF5320 PF17253.2 KNZ76342.1 - 0.17 13.0 0.7 0.44 11.6 0.3 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF4337 PF14235.6 KNZ76342.1 - 0.2 11.8 0.2 0.2 11.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Cortex-I_coil PF09304.10 KNZ76342.1 - 0.31 11.3 6.5 0.11 12.8 1.9 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil Tropomyosin_1 PF12718.7 KNZ76342.1 - 0.55 10.4 9.1 0.12 12.5 4.2 1.8 1 1 0 1 1 1 0 Tropomyosin like TMF_DNA_bd PF12329.8 KNZ76342.1 - 0.8 9.7 9.3 0.12 12.3 5.5 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 KNZ76342.1 - 7.1 6.7 10.9 16 5.5 10.9 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 KNZ76342.1 - 8.1 5.7 11.9 4.4 6.5 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TPR_2 PF07719.17 KNZ76343.1 - 2.4e-05 24.1 6.8 0.00019 21.3 1.8 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ76343.1 - 6.5e-05 22.5 2.8 6.5e-05 22.5 2.8 2.3 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 KNZ76343.1 - 0.0034 18.1 0.1 0.039 14.8 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ76343.1 - 0.0044 17.3 2.7 0.15 12.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ76343.1 - 0.011 15.6 3.1 0.011 15.6 3.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 KNZ76344.1 - 2.4e-48 164.3 49.8 2.5e-34 118.6 27.1 4.0 5 0 0 5 5 5 2 ABC-2 type transporter ABC_tran PF00005.27 KNZ76344.1 - 6.3e-32 111.0 0.1 6.9e-15 55.8 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KNZ76344.1 - 2.1e-20 72.4 2.6 3.2e-16 59.0 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter AAA_16 PF13191.6 KNZ76344.1 - 3.3e-06 27.6 0.2 0.0068 16.8 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 KNZ76344.1 - 1.2e-05 25.9 0.0 0.019 15.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KNZ76344.1 - 0.00013 22.2 1.0 0.57 10.5 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KNZ76344.1 - 0.00014 22.0 0.0 0.047 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KNZ76344.1 - 0.00017 22.0 0.2 1 9.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain ABC_trans_N PF14510.6 KNZ76344.1 - 0.0005 20.6 3.4 0.0042 17.7 3.4 2.4 1 1 0 1 1 1 1 ABC-transporter N-terminal cobW PF02492.19 KNZ76344.1 - 0.00066 19.3 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KNZ76344.1 - 0.0013 19.0 0.4 0.43 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KNZ76344.1 - 0.0032 17.4 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 1 1 RsgA GTPase AAA_21 PF13304.6 KNZ76344.1 - 0.0052 16.6 0.0 1.2 8.9 0.0 2.5 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KNZ76344.1 - 0.0059 16.3 1.5 2.9 7.6 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KNZ76344.1 - 0.0073 16.0 0.4 0.13 12.0 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KNZ76344.1 - 0.008 15.6 0.0 0.14 11.6 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain TM2 PF05154.16 KNZ76344.1 - 0.011 16.1 2.7 0.011 16.1 2.7 2.6 2 0 0 2 2 1 0 TM2 domain AAA_25 PF13481.6 KNZ76344.1 - 0.023 14.3 0.2 0.32 10.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KNZ76344.1 - 0.39 11.1 4.0 3.2 8.1 0.3 2.9 2 1 0 2 2 2 0 AAA domain Glyco_hydro_cc PF11790.8 KNZ76345.1 - 1.1e-59 202.0 3.2 1.3e-59 201.7 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF-hand_5 PF13202.6 KNZ76346.1 - 1e-07 31.1 0.1 1.2e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 KNZ76346.1 - 1.6e-07 30.6 0.1 0.0038 17.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KNZ76346.1 - 2.4e-05 24.7 0.3 2.4e-05 24.7 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 KNZ76346.1 - 0.00039 19.8 0.2 0.02 14.4 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KNZ76346.1 - 0.12 12.2 0.1 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Dopey_N PF04118.14 KNZ76347.1 - 2.2e-109 365.3 0.4 7.8e-109 363.5 0.1 2.2 2 0 0 2 2 2 1 Dopey, N-terminal Mycobact_memb PF05423.13 KNZ76347.1 - 0.33 10.9 2.7 0.44 10.5 0.1 2.5 3 0 0 3 3 3 0 Mycobacterium membrane protein zf-CCHC PF00098.23 KNZ76348.1 - 0.35 11.0 3.9 0.77 9.9 3.9 1.6 1 0 0 1 1 1 0 Zinc knuckle PBP1_TM PF14812.6 KNZ76349.1 - 0.64 10.4 12.4 0.43 11.0 8.8 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GFA PF04828.14 KNZ76350.1 - 1.4e-12 47.8 1.6 2.2e-12 47.1 1.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ATP-synt_E PF05680.12 KNZ76351.1 - 7.9e-17 61.4 0.3 7.9e-17 61.4 0.3 1.6 2 0 0 2 2 2 1 ATP synthase E chain LdpA_C PF12617.8 KNZ76351.1 - 0.099 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal CAF1C_H4-bd PF12265.8 KNZ76352.1 - 2.7e-29 101.2 1.4 6e-29 100.1 0.8 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KNZ76352.1 - 3.2e-18 65.7 12.4 1.3e-05 25.9 0.5 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat RAMP4 PF06624.12 KNZ76353.1 - 3e-19 68.8 0.0 3.3e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF2431 PF10354.9 KNZ76354.1 - 7.7e-53 179.2 0.0 1e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) MRP-L46 PF11788.8 KNZ76354.1 - 0.11 13.2 2.3 6.3 7.6 2.0 2.6 3 0 0 3 3 3 0 39S mitochondrial ribosomal protein L46 PBP1_TM PF14812.6 KNZ76354.1 - 0.78 10.2 4.2 0.28 11.6 1.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fip1 PF05182.13 KNZ76356.1 - 2.1e-20 72.0 1.4 3.5e-20 71.2 1.4 1.4 1 0 0 1 1 1 1 Fip1 motif Ribosomal_60s PF00428.19 KNZ76356.1 - 3.5 8.3 9.2 2 9.0 2.9 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Adeno_terminal PF02459.15 KNZ76356.1 - 7.3 4.9 6.8 11 4.3 6.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein ING PF12998.7 KNZ76357.1 - 8.6e-14 52.0 1.0 1.3e-13 51.4 1.0 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KNZ76357.1 - 2.3e-06 27.4 6.0 3.9e-06 26.6 6.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KNZ76357.1 - 0.14 11.7 1.6 0.27 10.8 1.6 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 KNZ76357.1 - 0.17 12.2 0.6 0.44 10.8 0.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DASH_Dam1 PF08653.10 KNZ76357.1 - 0.21 11.4 0.6 5.3 6.9 0.0 2.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 CE2_N PF17996.1 KNZ76359.1 - 3.8e-06 26.8 0.8 0.0021 18.0 0.1 2.6 2 1 0 2 2 2 2 Carbohydrate esterase 2 N-terminal APOBEC4_like PF18774.1 KNZ76360.1 - 0.09 12.7 1.0 1.8 8.5 0.0 3.3 3 0 0 3 3 3 0 APOBEC4-like -AID/APOBEC-deaminase RNase_H PF00075.24 KNZ76361.1 - 1.5e-31 109.5 0.0 2.5e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 KNZ76361.1 - 1.5e-20 73.2 1.7 2.8e-20 72.3 1.7 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin TPP1 PF10341.9 KNZ76361.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD NIF PF03031.18 KNZ76362.1 - 3.8e-25 88.5 0.0 7.9e-24 84.2 0.0 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 KNZ76362.1 - 9e-09 35.2 0.2 9.5e-08 31.9 0.1 2.4 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 KNZ76362.1 - 9.5e-05 22.7 0.0 0.00076 19.8 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain SIKE PF05769.11 KNZ76363.1 - 5.2e-09 36.3 14.9 1.5e-05 25.1 7.7 3.1 2 1 1 3 3 3 2 SIKE family RGCC PF15151.6 KNZ76363.1 - 0.018 15.3 0.9 0.043 14.0 0.6 1.8 1 1 1 2 2 2 0 Response gene to complement 32 protein family Mito_fiss_reg PF05308.11 KNZ76363.1 - 0.09 12.8 1.9 0.21 11.6 1.9 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator Csm1_N PF18504.1 KNZ76363.1 - 0.73 10.2 5.1 15 6.0 0.9 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain GnHR_trans PF12369.8 KNZ76364.1 - 0.062 14.1 0.1 0.12 13.2 0.1 1.4 1 0 0 1 1 1 0 Gonadotropin hormone receptor transmembrane region SLT_L PF14718.6 KNZ76368.1 - 0.16 12.1 2.0 0.3 11.2 2.0 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain APH PF01636.23 KNZ76369.1 - 2.2e-12 47.4 0.0 3.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KNZ76369.1 - 4.6e-05 22.9 0.0 0.0031 16.9 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase DUF1679 PF07914.11 KNZ76369.1 - 0.00031 19.7 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 KNZ76369.1 - 0.096 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.23 KNZ76370.1 - 5.8e-69 232.5 0.0 8.1e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KNZ76370.1 - 1.2e-15 57.2 0.0 4.2e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KNZ76370.1 - 8.3e-15 55.1 0.0 1.1e-13 51.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ76370.1 - 1.1e-08 35.3 0.0 3.5e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNZ76370.1 - 2.1e-06 27.6 0.0 4.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 KNZ76370.1 - 2.6e-06 27.2 16.6 2.9e-05 23.8 15.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ76370.1 - 2.6e-06 27.2 15.7 5.2e-06 26.2 15.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ76370.1 - 0.00029 20.6 13.1 0.00054 19.8 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ76370.1 - 0.00031 20.7 15.2 0.00062 19.7 14.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 KNZ76370.1 - 0.00032 20.8 14.0 0.00068 19.7 14.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KNZ76370.1 - 0.00052 20.3 15.6 0.0011 19.2 15.6 1.6 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.15 KNZ76370.1 - 0.02 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-RING_5 PF14634.6 KNZ76370.1 - 0.035 14.1 13.6 0.067 13.2 13.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.8 KNZ76370.1 - 0.18 11.7 8.4 0.46 10.3 8.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KNZ76370.1 - 0.93 9.4 5.6 2.1 8.3 5.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.20 KNZ76370.1 - 0.99 9.2 10.7 2 8.2 10.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Cpn60_TCP1 PF00118.24 KNZ76371.1 - 4.5e-157 523.6 1.9 5.1e-157 523.4 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bot1p PF12298.8 KNZ76372.1 - 2.8e-29 102.5 0.8 2.8e-29 102.5 0.8 2.1 2 1 0 3 3 3 1 Eukaryotic mitochondrial regulator protein Methyltransf_16 PF10294.9 KNZ76373.1 - 9.7e-15 54.7 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KNZ76373.1 - 0.004 16.7 0.0 0.0084 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KNZ76373.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FAM86 PF14904.6 KNZ76373.1 - 0.083 13.0 0.2 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function DUF2530 PF10745.9 KNZ76373.1 - 0.14 12.5 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) WLM PF08325.10 KNZ76374.1 - 2.8e-57 193.9 0.0 3.8e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KNZ76374.1 - 0.0011 19.1 0.2 0.0024 18.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SVIP PF15811.5 KNZ76374.1 - 0.018 15.5 2.4 0.28 11.7 0.0 2.4 2 0 0 2 2 2 0 Small VCP/p97-interacting protein SprT-like PF10263.9 KNZ76374.1 - 0.069 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 SprT-like family Methyltransf_25 PF13649.6 KNZ76375.1 - 8.3e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ76375.1 - 4.7e-10 39.5 0.0 9.3e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ76375.1 - 5.5e-10 39.8 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ76375.1 - 9.1e-10 38.5 0.0 1.6e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ76375.1 - 1.6e-05 25.5 0.0 4.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KNZ76375.1 - 0.0098 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KNZ76375.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KNZ76375.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase SF3b10 PF07189.11 KNZ76376.1 - 1.1e-27 96.0 0.0 1.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Sas10_Utp3 PF04000.15 KNZ76377.1 - 1.4e-16 60.8 0.0 4.8e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family F-box-like PF12937.7 KNZ76378.1 - 2.7e-05 24.0 0.0 0.00013 21.8 0.0 2.2 1 1 0 1 1 1 1 F-box-like PK_C PF02887.16 KNZ76378.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain LRR_1 PF00560.33 KNZ76378.1 - 0.036 14.6 8.7 2.7 8.9 0.2 7.0 7 1 0 7 7 7 0 Leucine Rich Repeat STAS_2 PF13466.6 KNZ76378.1 - 0.11 12.9 1.6 8 6.9 0.2 3.5 2 1 1 3 3 3 0 STAS domain LRR_6 PF13516.6 KNZ76378.1 - 1 9.6 10.9 32 4.9 0.3 6.5 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.7 KNZ76378.1 - 1.8 9.1 16.6 3.1 8.4 0.2 6.2 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) Sec1 PF00995.23 KNZ76379.1 - 9.7e-112 375.1 0.0 1.4e-111 374.6 0.0 1.2 1 0 0 1 1 1 1 Sec1 family cNMP_binding PF00027.29 KNZ76379.1 - 1.7e-27 95.3 0.0 4.7e-15 55.4 0.0 4.7 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KNZ76379.1 - 2.4e-16 60.5 6.2 3.6e-10 40.4 4.8 2.8 2 0 0 2 2 2 2 Patatin-like phospholipase DNA_pol_A PF00476.20 KNZ76379.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family A ICL PF00463.21 KNZ76380.1 - 1.7e-195 650.5 0.3 1.9e-195 650.3 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KNZ76380.1 - 4.6e-11 42.6 0.7 1.1e-09 38.1 0.0 2.7 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase MMM1 PF10296.9 KNZ76381.1 - 3.4e-05 23.1 1.1 5.4e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 KNZ76381.1 - 0.015 15.8 0.0 0.11 13.1 0.0 2.4 1 1 0 1 1 1 0 PH domain PH_9 PF15410.6 KNZ76381.1 - 0.064 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain PAM2 PF07145.15 KNZ76381.1 - 1.5 8.6 5.6 0.51 10.2 1.4 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Fes1 PF08609.10 KNZ76382.1 - 1.9e-24 86.3 2.0 1.6e-23 83.4 0.3 3.0 4 0 0 4 4 4 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 KNZ76382.1 - 0.0022 18.3 0.0 0.61 10.5 0.0 3.0 2 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 KNZ76382.1 - 0.025 15.1 0.0 9.6 6.8 0.0 3.3 2 1 0 2 2 2 0 HEAT-like repeat Cnd1 PF12717.7 KNZ76382.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KNZ76382.1 - 0.091 13.1 0.0 7.6 7.1 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat Exo5 PF09810.9 KNZ76384.1 - 4.3e-69 233.7 0.0 7e-68 229.8 0.0 2.4 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 KNZ76384.1 - 5e-06 26.6 0.1 7.9e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF5082 PF16888.5 KNZ76385.1 - 0.013 15.8 2.0 0.013 15.8 2.0 8.6 3 2 4 8 8 8 0 Domain of unknown function (DUF5082) Surfac_D-trimer PF09006.11 KNZ76385.1 - 0.19 11.7 0.6 29 4.6 0.0 4.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation LPP PF04728.13 KNZ76385.1 - 0.56 10.6 0.0 0.56 10.6 0.0 9.6 9 2 2 11 11 11 0 Lipoprotein leucine-zipper ORF11CD3 PF10549.9 KNZ76385.1 - 1.1 9.4 6.2 2.6 8.3 0.4 3.9 3 0 0 3 3 3 0 ORF11CD3 domain Yae1_N PF09811.9 KNZ76386.1 - 2e-10 40.2 5.5 3.5e-10 39.4 5.5 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Frigida PF07899.11 KNZ76386.1 - 0.25 10.6 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein Corona_nucleoca PF00937.18 KNZ76387.1 - 1.3 8.0 4.3 7.5 5.5 0.7 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein BTB_2 PF02214.22 KNZ76388.1 - 0.0006 20.1 0.0 0.0044 17.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain BTB_3 PF16017.5 KNZ76388.1 - 0.16 12.1 0.0 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain PTE PF02126.18 KNZ76388.1 - 0.19 11.2 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 Phosphotriesterase family WD40 PF00400.32 KNZ76389.1 - 5.9e-36 121.9 18.3 1.3e-06 29.0 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ76389.1 - 3.3e-17 62.6 0.0 0.0035 17.6 0.1 5.3 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ76389.1 - 0.00025 20.1 0.4 1.8 7.5 0.0 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ76389.1 - 0.0007 19.5 0.0 0.39 10.6 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KNZ76389.1 - 0.012 14.9 0.0 11 5.2 0.0 3.4 3 1 0 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KNZ76389.1 - 0.14 10.7 0.0 0.23 10.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Retrotran_gag_2 PF14223.6 KNZ76390.1 - 0.0057 16.3 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AFG1_ATPase PF03969.16 KNZ76392.1 - 7.6e-18 64.5 0.0 9.2e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase DUF269 PF03270.13 KNZ76392.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF269 Plavaka PF18759.1 KNZ76393.1 - 4.1e-19 69.0 0.2 6.7e-19 68.3 0.2 1.3 1 0 0 1 1 1 1 Plavaka transposase Gpr1_Fun34_YaaH PF01184.19 KNZ76395.1 - 4.1e-27 95.1 3.6 5e-27 94.9 3.6 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 KNZ76396.1 - 8.5e-60 201.9 18.7 9.2e-60 201.8 18.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family cIII PF08134.11 KNZ76396.1 - 0.02 14.6 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 0 cIII protein family p450 PF00067.22 KNZ76397.1 - 5.6e-28 97.9 0.0 8.2e-28 97.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3951 PF13131.6 KNZ76397.1 - 0.02 15.1 0.9 0.044 14.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) DUF1819 PF08849.11 KNZ76397.1 - 0.062 13.1 0.1 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) DUF1201 PF06716.11 KNZ76397.1 - 0.078 13.0 2.2 0.085 12.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) CE2_N PF17996.1 KNZ76398.1 - 0.00023 21.1 0.1 0.0076 16.2 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal VSP PF03302.13 KNZ76398.1 - 0.047 12.5 0.2 0.072 11.9 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein TPR_10 PF13374.6 KNZ76399.1 - 4.2e-27 93.2 0.9 3.4e-08 33.1 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ76399.1 - 1.2e-26 92.7 5.8 8.5e-15 54.8 0.5 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ76399.1 - 1.2e-05 25.0 3.0 0.23 11.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ76399.1 - 5.3e-05 23.8 0.7 0.00062 20.4 0.2 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4404) TPR_2 PF07719.17 KNZ76399.1 - 0.00024 20.9 1.8 6.2 7.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ76399.1 - 0.0006 19.5 1.0 5.1 7.1 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ76399.1 - 0.00074 19.0 3.4 0.0023 17.3 3.5 1.5 1 1 0 1 1 1 1 MalT-like TPR region TPR_17 PF13431.6 KNZ76399.1 - 0.0019 18.5 0.2 0.46 11.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Eno-Rase_FAD_bd PF07055.12 KNZ76399.1 - 0.012 16.0 0.0 0.47 10.9 0.0 2.2 1 1 1 2 2 2 0 Enoyl reductase FAD binding domain TPR_16 PF13432.6 KNZ76399.1 - 0.013 16.2 1.4 3.1 8.5 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF294_C PF10335.9 KNZ76399.1 - 0.025 14.4 2.7 0.59 9.9 0.8 2.3 2 1 0 2 2 2 0 Putative nucleotidyltransferase substrate binding domain DUF4054 PF13262.6 KNZ76399.1 - 0.045 13.8 0.2 1.7 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4054) FAD-SLDH PF12318.8 KNZ76399.1 - 0.045 13.8 1.2 0.17 11.9 0.9 1.7 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ala_racemase_N PF01168.20 KNZ76399.1 - 0.06 13.0 1.1 0.095 12.3 0.6 1.5 1 1 1 2 2 2 0 Alanine racemase, N-terminal domain TPR_5 PF12688.7 KNZ76399.1 - 0.063 13.5 2.0 2.4 8.4 1.0 2.6 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_14 PF13428.6 KNZ76399.1 - 0.091 13.6 5.2 17 6.5 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Epimerase_2 PF02350.19 KNZ76402.1 - 3.9e-35 121.3 0.1 1.4e-34 119.5 0.1 1.7 1 1 0 2 2 2 1 UDP-N-acetylglucosamine 2-epimerase Herpes_Helicase PF02689.14 KNZ76403.1 - 5.4e-07 28.0 0.0 5.6e-07 27.9 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ76403.1 - 0.00099 18.9 0.1 0.0029 17.4 0.1 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Asp_protease_2 PF13650.6 KNZ76405.1 - 0.00065 20.3 0.0 0.0015 19.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ76405.1 - 0.0014 19.1 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Chromo PF00385.24 KNZ76407.1 - 2.1e-15 56.3 0.1 2.6e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ76407.1 - 0.037 14.2 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 KNZ76407.1 - 0.084 12.8 0.8 0.1 12.5 0.8 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain TPR_10 PF13374.6 KNZ76408.1 - 2e-102 332.7 15.5 2.1e-08 33.7 0.0 12.4 11 1 1 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ76408.1 - 1.1e-95 314.0 28.7 6.7e-17 61.6 1.5 8.8 5 2 3 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ76408.1 - 2e-27 93.1 32.4 0.14 12.4 0.2 11.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ76408.1 - 6.4e-25 85.7 1.2 2.5 8.7 0.0 12.3 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ76408.1 - 7.5e-22 75.7 28.6 1.2 9.9 0.1 11.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ76408.1 - 1.3e-17 64.1 22.8 0.033 14.8 0.3 10.9 6 4 4 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ76408.1 - 2.7e-17 61.4 47.9 0.4 10.9 0.3 12.0 12 0 0 12 12 11 8 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ76408.1 - 7.3e-15 55.4 14.7 1 10.0 0.0 10.8 1 1 10 11 11 11 2 Domain of unknown function (DUF4404) TPR_MalT PF17874.1 KNZ76408.1 - 2.7e-14 53.3 33.3 0.00035 20.1 1.7 5.6 2 1 3 5 5 5 4 MalT-like TPR region TPR_7 PF13176.6 KNZ76408.1 - 4.4e-11 42.0 27.2 2.1 8.6 0.1 11.5 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ76408.1 - 2e-10 40.0 28.0 6.1 6.8 0.1 11.9 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_5 PF12688.7 KNZ76408.1 - 5.6e-08 33.0 21.6 1.5 9.0 0.9 7.5 1 1 7 8 8 8 7 Tetratrico peptide repeat TPR_19 PF14559.6 KNZ76408.1 - 3.2e-07 30.8 23.4 1.4 9.5 0.1 7.9 3 1 6 9 9 9 4 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ76408.1 - 2.2e-06 27.1 0.0 5.4e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KNZ76408.1 - 0.0022 18.3 0.0 0.012 15.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain PTR PF12789.7 KNZ76408.1 - 0.0025 17.8 0.4 32 4.7 0.0 5.5 8 0 0 8 8 5 0 Phage tail repeat like AAA_7 PF12775.7 KNZ76408.1 - 0.04 13.4 0.1 0.08 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sec7 PF01369.20 KNZ76408.1 - 0.053 13.2 3.0 2.2 8.0 0.3 4.8 3 1 1 5 5 4 0 Sec7 domain AAA_5 PF07728.14 KNZ76408.1 - 0.064 13.2 0.0 0.52 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PTS_EIIA_2 PF00359.22 KNZ76408.1 - 0.13 12.2 3.9 12 5.8 0.1 5.0 4 1 2 6 6 6 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Gtr1_RagA PF04670.12 KNZ76408.1 - 0.13 11.5 0.4 0.66 9.3 0.0 2.2 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region Nup54_C PF18437.1 KNZ76408.1 - 0.71 9.8 3.3 0.53 10.2 0.5 2.3 2 0 0 2 2 2 0 Nup54 C-terminal interacting domain Holin_BhlA PF10960.8 KNZ76408.1 - 1.2 9.2 7.8 22 5.1 0.3 6.2 9 0 0 9 9 7 0 BhlA holin family PPR_1 PF12854.7 KNZ76408.1 - 2.4 7.9 29.9 38 4.1 0.0 10.2 11 0 0 11 11 11 0 PPR repeat RT_RNaseH PF17917.1 KNZ76410.1 - 6.5e-11 42.5 0.0 1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76410.1 - 1.3e-09 38.0 0.1 8.7e-09 35.3 0.1 2.0 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Tim17 PF02466.19 KNZ76411.1 - 0.15 12.4 0.1 0.15 12.4 0.1 3.0 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family NAGLU_N PF12971.7 KNZ76413.1 - 0.0031 17.3 0.3 0.0094 15.7 0.0 1.9 2 0 0 2 2 2 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DBB PF14545.6 KNZ76415.1 - 0.13 12.1 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, TFIID-18kDa PF02269.16 KNZ76417.1 - 5.1e-32 109.8 0.1 1.1e-31 108.7 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIE-A_C PF11521.8 KNZ76417.1 - 0.0025 18.1 2.4 0.004 17.4 1.1 2.0 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Asp_protease PF09668.10 KNZ76418.1 - 4.2e-59 197.8 0.1 1.1e-58 196.4 0.1 1.7 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ76418.1 - 4.1e-21 75.3 0.0 1.1e-20 74.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76418.1 - 6.5e-11 42.7 0.1 2.4e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 KNZ76418.1 - 8.1e-07 28.7 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.20 KNZ76418.1 - 0.0013 19.1 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 KNZ76418.1 - 0.0036 17.1 0.0 0.0079 16.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.31 KNZ76418.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 UBA/TS-N domain XPC-binding PF09280.11 KNZ76418.1 - 0.026 14.3 2.8 0.026 14.3 2.8 1.8 2 0 0 2 2 2 0 XPC-binding domain UBA_4 PF14555.6 KNZ76418.1 - 0.059 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF3322 PF11795.8 KNZ76418.1 - 0.11 12.5 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Atg29_N PF18388.1 KNZ76419.1 - 1.5e-06 27.9 0.3 2.5e-06 27.2 0.3 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain UPF0029 PF01205.19 KNZ76420.1 - 8.4e-31 106.4 0.0 1.4e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KNZ76420.1 - 1.6e-06 28.4 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain Aldedh PF00171.22 KNZ76421.1 - 8.9e-163 542.1 0.2 1e-162 541.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAA_hydrolase PF01557.18 KNZ76422.1 - 2.3e-34 119.0 0.0 3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family CDC14 PF08045.11 KNZ76423.1 - 1.9e-28 99.4 2.1 6.4e-22 78.0 0.3 3.1 2 1 0 2 2 2 2 Cell division control protein 14, SIN component HisKA_3 PF07730.13 KNZ76423.1 - 0.036 14.6 0.6 0.21 12.1 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase Coiled-coil_56 PF09813.9 KNZ76424.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 Fungus-induced PF10917.8 KNZ76425.1 - 0.52 10.7 1.9 0.73 10.2 1.9 1.2 1 0 0 1 1 1 0 Fungus-induced protein DASH_Spc19 PF08287.11 KNZ76426.1 - 1.1e-10 41.7 1.4 6.8e-07 29.3 0.0 2.1 1 1 1 2 2 2 2 Spc19 CASP_C PF08172.12 KNZ76426.1 - 0.017 14.5 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 CASP C terminal NifW PF03206.14 KNZ76426.1 - 0.16 12.5 0.7 0.26 11.8 0.2 1.6 2 0 0 2 2 2 0 Nitrogen fixation protein NifW NuA4 PF09340.10 KNZ76426.1 - 0.26 11.2 2.2 0.45 10.4 2.2 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 Tnp_22_trimer PF17489.2 KNZ76426.1 - 9.1 6.3 9.2 8 6.5 0.2 2.3 2 0 0 2 2 2 0 L1 transposable element trimerization domain VWA_2 PF13519.6 KNZ76427.1 - 0.0042 17.7 0.0 0.03 15.0 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KNZ76427.1 - 0.0059 16.9 0.0 0.031 14.5 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 KNZ76427.1 - 0.0072 16.5 0.1 0.022 14.8 0.1 1.7 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 KNZ76427.1 - 0.071 13.0 0.1 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain GCP_N_terminal PF17681.1 KNZ76428.1 - 7.8e-39 134.1 0.0 1.3e-38 133.4 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KNZ76428.1 - 1.6e-32 113.2 3.2 1.6e-32 113.2 3.2 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Ribosomal_L1 PF00687.21 KNZ76429.1 - 2.2e-43 148.4 1.1 2.7e-43 148.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Mgm101p PF06420.12 KNZ76430.1 - 5.1e-71 237.7 0.1 1.2e-70 236.5 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MoCF_biosynth PF00994.24 KNZ76431.1 - 1.7e-58 196.4 0.2 2.2e-28 98.7 0.1 2.6 2 1 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KNZ76431.1 - 1.7e-32 112.4 0.1 2.5e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KNZ76431.1 - 2.1e-15 56.7 0.3 6.9e-15 55.0 0.1 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) PDZ_2 PF13180.6 KNZ76431.1 - 0.24 11.7 1.3 1.6 9.1 0.0 2.8 3 0 0 3 3 3 0 PDZ domain DUF498 PF04430.14 KNZ76432.1 - 1.5e-33 115.1 0.0 2e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) CHCH PF06747.13 KNZ76434.1 - 0.00041 20.4 13.5 0.00053 20.0 6.6 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 KNZ76434.1 - 0.0012 18.8 11.4 0.028 14.4 5.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 KNZ76434.1 - 4.8 7.5 11.0 36 4.8 9.1 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KNZ76434.1 - 8.3 6.5 15.1 14 5.7 4.8 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-MYND PF01753.18 KNZ76435.1 - 1.9e-09 37.4 10.6 3.8e-09 36.5 10.6 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 KNZ76435.1 - 0.00057 19.7 7.3 0.0011 18.8 7.3 1.5 1 0 0 1 1 1 1 HIT zinc finger DUF2202 PF09968.9 KNZ76435.1 - 0.00081 19.3 0.1 0.097 12.5 0.1 2.9 2 1 1 3 3 3 1 Uncharacterized protein domain (DUF2202) KinB_sensor PF16767.5 KNZ76435.1 - 0.053 14.0 0.0 0.57 10.6 0.0 2.2 1 1 1 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB zf-C6H2 PF15801.5 KNZ76435.1 - 0.16 12.3 6.0 0.4 11.0 6.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CNH PF00780.22 KNZ76436.1 - 8.3e-05 22.3 0.0 0.0026 17.4 0.0 2.2 2 0 0 2 2 2 2 CNH domain TRP PF06011.12 KNZ76437.1 - 3.8e-26 91.8 15.8 2.3e-20 72.8 7.5 2.3 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel GatB_N PF02934.15 KNZ76438.1 - 3.1e-106 354.8 0.0 4e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 KNZ76438.1 - 7.3e-27 94.1 0.4 4.4e-26 91.5 0.4 2.1 1 1 0 1 1 1 1 GatB domain DUF108 PF01958.18 KNZ76439.1 - 0.046 14.1 0.2 0.083 13.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF108 DeoC PF01791.9 KNZ76440.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase LEA_6 PF10714.9 KNZ76440.1 - 0.27 11.3 7.8 0.19 11.8 1.2 3.3 3 0 0 3 3 3 0 Late embryogenesis abundant protein 18 Myb_CC_LHEQLE PF14379.6 KNZ76444.1 - 0.19 11.5 0.8 0.43 10.3 0.8 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif PAP_central PF04928.17 KNZ76445.1 - 1.4e-104 348.5 0.0 1.8e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KNZ76445.1 - 2.8e-56 189.8 0.0 4.8e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KNZ76445.1 - 1.4e-11 44.5 0.0 3.8e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KNZ76445.1 - 0.049 13.4 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Beta_helix PF13229.6 KNZ76446.1 - 6e-09 35.9 20.9 2.5e-08 33.9 17.2 2.8 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 KNZ76446.1 - 0.00097 18.5 8.3 0.025 13.9 2.3 2.4 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF4381 PF14316.6 KNZ76446.1 - 0.19 12.0 0.7 0.29 11.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Rhomboid PF01694.22 KNZ76449.1 - 9.9e-08 32.1 7.9 1.5e-07 31.6 7.9 1.2 1 0 0 1 1 1 1 Rhomboid family CUE PF02845.16 KNZ76449.1 - 4.8e-07 29.3 0.1 8e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain DER1 PF04511.15 KNZ76449.1 - 0.00067 19.6 6.1 0.00097 19.1 6.1 1.2 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 KNZ76449.1 - 0.0074 16.8 0.3 0.018 15.6 0.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) E3_UbLigase_EDD PF11547.8 KNZ76449.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.3 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD eIF-3_zeta PF05091.12 KNZ76450.1 - 5.6e-212 705.3 0.0 6.4e-212 705.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 KNZ76451.1 - 2.2e-19 69.0 0.0 3.8e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ76451.1 - 2.1e-07 31.0 0.0 4.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 KNZ76451.1 - 0.0016 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_polI_A34 PF08208.11 KNZ76451.1 - 0.0065 16.6 8.9 0.0096 16.0 8.9 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF3464 PF11947.8 KNZ76451.1 - 0.0079 16.0 0.9 0.017 14.8 0.9 1.6 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Presenilin PF01080.17 KNZ76451.1 - 0.059 12.1 2.3 0.083 11.6 2.3 1.2 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 KNZ76451.1 - 0.23 10.4 7.0 0.31 9.9 7.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 KNZ76451.1 - 0.28 9.4 5.1 0.39 9.0 5.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 KNZ76451.1 - 0.85 9.3 2.1 1.5 8.5 2.1 1.4 1 0 0 1 1 1 0 Connexin Nop14 PF04147.12 KNZ76452.1 - 2.7e-271 902.7 43.4 1.4e-153 513.3 2.1 2.3 1 1 1 2 2 2 2 Nop14-like family PI3_PI4_kinase PF00454.27 KNZ76453.1 - 6.6e-53 180.1 0.0 1.5e-52 178.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KNZ76453.1 - 2.3e-33 115.8 0.1 2.3e-33 115.8 0.1 2.4 3 0 0 3 3 3 1 FAT domain UME PF08064.13 KNZ76453.1 - 1.7e-23 82.5 0.0 6.7e-21 74.1 0.0 3.8 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 KNZ76453.1 - 2.1e-11 43.4 0.3 5.7e-11 42.0 0.3 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 KNZ76453.1 - 0.00071 19.5 0.0 0.0099 15.8 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Radial_spoke PF04712.12 KNZ76453.1 - 0.041 12.8 0.1 0.083 11.8 0.1 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein YEATS PF03366.16 KNZ76454.1 - 4.8e-38 129.0 0.1 8.8e-38 128.2 0.1 1.4 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 KNZ76454.1 - 0.0045 16.2 4.4 0.0063 15.7 4.4 1.1 1 0 0 1 1 1 1 Peptidase M16C associated Dscam_C PF12355.8 KNZ76455.1 - 0.16 12.9 6.8 1.5 9.8 0.2 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal Thioredoxin_4 PF13462.6 KNZ76456.1 - 1.8e-07 31.5 0.0 3.3e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DIOX_N PF14226.6 KNZ76457.1 - 9.4e-23 81.2 0.0 2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ76457.1 - 5.3e-15 55.7 0.0 1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PCI PF01399.27 KNZ76459.1 - 1.4e-13 51.2 0.0 2.5e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 PCI domain Peptidase_S10 PF00450.22 KNZ76460.1 - 2.1e-88 297.5 0.0 2.7e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase rve PF00665.26 KNZ76464.1 - 0.04 14.1 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Pinin_SDK_N PF04697.13 KNZ76465.1 - 2.5 8.7 9.1 0.52 10.9 3.0 2.4 2 0 0 2 2 2 0 pinin/SDK conserved region RT_RNaseH PF17917.1 KNZ76466.1 - 1.7e-10 41.1 0.0 5e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76466.1 - 7.2e-08 32.4 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Herpes_pp85 PF04637.12 KNZ76467.1 - 0.15 10.4 1.4 0.3 9.5 1.4 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PCNA_N PF00705.18 KNZ76468.1 - 1.2e-19 70.2 3.5 2.2e-19 69.4 3.5 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KNZ76468.1 - 3.6e-19 69.2 0.7 7.2e-12 45.6 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Nop14 PF04147.12 KNZ76468.1 - 0.0028 15.9 12.4 0.0034 15.7 12.4 1.1 1 0 0 1 1 1 1 Nop14-like family GAGA_bind PF06217.12 KNZ76468.1 - 0.0059 16.9 8.0 0.007 16.7 8.0 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Presenilin PF01080.17 KNZ76468.1 - 0.091 11.5 4.4 0.11 11.3 4.4 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 KNZ76468.1 - 0.24 11.2 12.7 0.37 10.6 12.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HGTP_anticodon2 PF12745.7 KNZ76468.1 - 0.29 10.6 8.4 0.4 10.1 8.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF913 PF06025.12 KNZ76468.1 - 0.62 9.0 6.4 0.27 10.2 3.5 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 KNZ76468.1 - 1.2 9.1 3.6 1.7 8.7 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 KNZ76468.1 - 2.9 6.1 17.0 3.8 5.7 17.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Helitron_like_N PF14214.6 KNZ76470.1 - 5.8e-23 82.1 0.5 7.5e-23 81.7 0.5 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KNZ76471.1 - 1.8e-17 64.2 0.1 2.2e-17 63.9 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ76471.1 - 0.072 13.0 0.1 0.083 12.8 0.1 1.1 1 0 0 1 1 1 0 Inovirus Gp2 MitMem_reg PF13012.6 KNZ76472.1 - 0.032 14.6 0.0 0.033 14.6 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function RFX5_N PF18326.1 KNZ76472.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 RFX5 N-terminal domain PIF1 PF05970.14 KNZ76473.1 - 1.7e-50 172.3 0.1 1.8e-50 172.1 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76473.1 - 0.00064 19.5 0.0 0.00083 19.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ76473.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ76473.1 - 0.038 14.0 0.0 0.078 13.0 0.0 1.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 KNZ76473.1 - 0.082 12.5 0.1 0.085 12.4 0.1 1.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ76473.1 - 0.12 12.7 0.1 0.73 10.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase PIF1 PF05970.14 KNZ76474.1 - 9.4e-33 113.9 0.0 1.1e-32 113.7 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ76474.1 - 0.0038 16.9 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Herpes_Helicase PF02689.14 KNZ76475.1 - 5.7e-06 24.6 0.0 5.9e-06 24.5 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ76475.1 - 0.091 12.6 0.1 0.23 11.3 0.1 1.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain BUD22 PF09073.10 KNZ76476.1 - 2.4 7.4 30.5 2.7 7.2 9.1 3.4 3 0 0 3 3 3 0 BUD22 Orai-1 PF07856.12 KNZ76477.1 - 0.19 11.4 4.6 0.4 10.4 4.6 1.5 1 0 0 1 1 1 0 Mediator of CRAC channel activity Amastin PF07344.11 KNZ76477.1 - 0.21 11.4 6.4 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF3149 PF11346.8 KNZ76477.1 - 1.7 8.4 4.6 1.3 8.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) SPC12 PF06645.13 KNZ76477.1 - 9.5 6.4 8.6 11 6.2 4.8 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Glyoxal_oxid_N PF07250.11 KNZ76478.1 - 5.6e-32 110.9 1.0 1.4e-14 53.9 0.0 5.5 4 1 2 6 6 6 3 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ76478.1 - 6.3e-22 77.7 0.8 1.3e-21 76.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KNZ76478.1 - 0.0098 15.9 0.1 0.48 10.5 0.1 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain NAD_binding_8 PF13450.6 KNZ76479.1 - 0.00055 20.1 0.2 0.0012 19.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TcpE PF12648.7 KNZ76480.1 - 0.32 11.5 0.1 0.32 11.5 0.1 2.5 2 1 0 2 2 2 0 TcpE family LANC_like PF05147.13 KNZ76481.1 - 1.8e-34 118.9 0.0 2.4e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.10 KNZ76481.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Pectic acid lyase DUF1917 PF08939.10 KNZ76482.1 - 3.3e-23 82.9 0.0 1e-22 81.3 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) PSRT PF07636.11 KNZ76482.1 - 0.081 12.6 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 PSRT DUF570 PF04489.13 KNZ76483.1 - 0.03 13.0 0.0 0.035 12.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF570) Fungal_trans PF04082.18 KNZ76485.1 - 3e-24 85.5 0.1 7.9e-24 84.1 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain HAD_2 PF13419.6 KNZ76486.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ76486.1 - 0.00087 19.6 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ76486.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like zf-4CXXC_R1 PF10497.9 KNZ76486.1 - 0.093 13.0 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase_fungal PF17667.1 KNZ76487.1 - 3.5e-36 124.8 0.3 8.4e-24 84.1 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KNZ76487.1 - 0.00073 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ76487.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RNase_H PF00075.24 KNZ76488.1 - 1e-09 38.7 0.2 1.8e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KNZ76488.1 - 0.00094 19.0 0.1 0.0035 17.2 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like zf-RVT PF13966.6 KNZ76489.1 - 0.012 16.3 1.7 0.021 15.5 1.9 1.5 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DUF5472 PF17566.2 KNZ76489.1 - 0.11 12.4 0.2 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5472) Pox_A_type_inc PF04508.12 KNZ76490.1 - 0.33 10.9 0.9 0.57 10.1 0.9 1.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Pkinase_fungal PF17667.1 KNZ76491.1 - 1.6e-16 60.2 0.0 1.9e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ76491.1 - 0.0012 18.8 0.0 0.0021 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KNZ76491.1 - 0.046 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 KNZ76491.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 KNZ76493.1 - 1.1e-14 54.1 0.0 1.4e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase HTH_32 PF13565.6 KNZ76493.1 - 0.034 14.8 0.4 0.18 12.5 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain LRR_4 PF12799.7 KNZ76494.1 - 0.019 15.4 7.2 12 6.4 0.0 5.9 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) NB-LRR PF12061.8 KNZ76494.1 - 0.097 12.0 0.6 0.19 11.0 0.2 1.6 2 0 0 2 2 2 0 Late blight resistance protein R1 RT_RNaseH PF17917.1 KNZ76495.1 - 1.6e-08 34.7 0.0 2.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76495.1 - 8.7e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Pkinase_fungal PF17667.1 KNZ76496.1 - 3.6e-19 68.8 0.0 5e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ76496.1 - 0.00021 21.3 0.0 0.00045 20.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KNZ76496.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase MFS_1 PF07690.16 KNZ76497.1 - 8.6e-40 136.7 39.9 8.6e-40 136.7 39.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ76497.1 - 4e-10 39.2 29.0 3.1e-09 36.2 28.5 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KNZ76497.1 - 3.4e-07 29.1 1.5 6.8e-07 28.1 1.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mersacidin PF16934.5 KNZ76497.1 - 0.14 11.9 1.3 0.62 9.9 0.1 2.5 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) DUF5362 PF17319.2 KNZ76497.1 - 0.76 9.7 5.6 1.6 8.6 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5362) DHHC PF01529.20 KNZ76497.1 - 9.3 6.4 11.0 1.3 9.2 0.2 3.7 2 2 2 4 4 4 0 DHHC palmitoyltransferase Glyco_hydro_61 PF03443.14 KNZ76498.1 - 1.5e-55 188.3 0.1 3e-55 187.3 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SSP160 PF06933.11 KNZ76498.1 - 9.3 4.3 21.5 14 3.8 21.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_61 PF03443.14 KNZ76499.1 - 8.9e-12 45.4 0.2 9.4e-12 45.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KNZ76500.1 - 1.7e-36 126.1 0.0 1.9e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ATP-synt_B PF00430.18 KNZ76501.1 - 0.053 13.6 0.6 0.085 13.0 0.6 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) WW PF00397.26 KNZ76502.1 - 9.1e-05 22.5 0.7 9.1e-05 22.5 0.7 2.3 2 0 0 2 2 2 1 WW domain Paf67 PF10255.9 KNZ76502.1 - 0.0034 16.4 0.6 0.0046 16.0 0.6 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 zf-RVT PF13966.6 KNZ76505.1 - 0.00048 20.8 2.5 0.00048 20.8 2.5 2.2 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase WW PF00397.26 KNZ76506.1 - 0.0047 17.0 1.3 0.0047 17.0 1.3 2.1 3 0 0 3 3 3 1 WW domain Paf67 PF10255.9 KNZ76506.1 - 0.013 14.5 1.0 0.018 14.1 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Acetyltransf_3 PF13302.7 KNZ76507.1 - 6.3e-09 36.6 0.2 9.7e-09 36.0 0.2 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Gpr1_Fun34_YaaH PF01184.19 KNZ76508.1 - 1.1e-69 234.2 17.3 1.5e-69 233.8 17.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family cIII PF08134.11 KNZ76508.1 - 0.041 13.6 0.3 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 cIII protein family RPA_interact_N PF14766.6 KNZ76508.1 - 0.49 10.1 4.9 8.9 6.0 0.3 2.3 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Asp_protease_2 PF13650.6 KNZ76509.1 - 0.044 14.4 0.0 0.051 14.2 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease Chromo PF00385.24 KNZ76512.1 - 2.9e-12 46.3 1.7 3.9e-12 45.9 1.7 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Flu_C_NS1 PF03506.13 KNZ76515.1 - 0.079 12.9 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) RT_RNaseH PF17917.1 KNZ76518.1 - 2.9e-06 27.5 0.0 3.1e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76518.1 - 0.0014 18.7 0.0 0.0023 17.9 0.0 1.3 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase CCM2_C PF16545.5 KNZ76518.1 - 0.075 13.6 0.0 0.077 13.5 0.0 1.1 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology RNase_H PF00075.24 KNZ76518.1 - 0.076 13.2 0.0 0.082 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase H Oxidored_FMN PF00724.20 KNZ76520.1 - 0.0018 17.6 0.0 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family I-EGF_1 PF18372.1 KNZ76520.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 SPOC PF07744.13 KNZ76520.1 - 0.19 11.7 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 SPOC domain DIOX_N PF14226.6 KNZ76521.1 - 6.6e-21 75.3 0.1 1.2e-20 74.4 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ76521.1 - 8.9e-14 51.8 0.0 1.8e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MbtH PF03621.13 KNZ76522.1 - 0.41 10.1 2.4 0.92 9.0 2.4 1.5 1 0 0 1 1 1 0 MbtH-like protein APH PF01636.23 KNZ76523.1 - 8.7e-06 25.8 0.1 0.00021 21.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ76523.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ76523.1 - 0.0048 16.3 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YjzC PF14168.6 KNZ76524.1 - 0.17 12.2 0.1 0.29 11.5 0.1 1.3 1 0 0 1 1 1 0 YjzC-like protein Abhydrolase_3 PF07859.13 KNZ76525.1 - 6.5e-52 176.4 0.9 7.6e-52 176.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KNZ76525.1 - 1.2e-05 24.5 0.1 3.8e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.7 KNZ76525.1 - 0.021 13.8 0.1 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KNZ76525.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KNZ76525.1 - 0.049 12.5 0.1 0.53 9.1 0.1 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_92 PF07971.12 KNZ76527.1 - 2.2e-152 508.2 1.5 2.7e-152 507.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KNZ76527.1 - 1.3e-26 94.0 0.3 2e-26 93.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain TraE PF05309.11 KNZ76527.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 TraE protein p450 PF00067.22 KNZ76528.1 - 1.1e-51 176.0 0.0 1.6e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cu-oxidase PF00394.22 KNZ76529.1 - 9.3e-43 146.1 0.1 7.6e-38 130.1 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ76529.1 - 4.6e-37 126.8 3.4 4.3e-36 123.7 0.1 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ76529.1 - 7.6e-37 126.0 1.1 8.7e-35 119.3 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase NAT PF04768.13 KNZ76530.1 - 1.1e-43 148.8 0.0 1.8e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 KNZ76530.1 - 3.1e-27 95.4 0.0 7.4e-27 94.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 KNZ76530.1 - 7.4e-24 84.7 0.0 1.5e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Metallophos PF00149.28 KNZ76531.1 - 1.5e-32 113.8 0.0 2.4e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_clus PF00172.18 KNZ76533.1 - 2.7e-10 40.2 8.7 4.2e-10 39.6 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNZ76533.1 - 8.1e-09 34.9 0.7 2.3e-05 23.5 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Hydrolase_4 PF12146.8 KNZ76534.1 - 4.3e-10 39.3 0.1 1.5e-07 31.0 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ76534.1 - 5.6e-07 29.5 0.1 3.5e-06 26.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KNZ76534.1 - 3e-06 27.3 0.0 0.00032 20.7 0.0 2.4 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KNZ76534.1 - 8.2e-06 26.6 0.1 0.0038 17.8 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KNZ76534.1 - 0.0056 16.5 0.0 0.026 14.3 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KNZ76534.1 - 0.006 16.1 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 KNZ76534.1 - 0.0064 16.1 0.0 1.6 8.2 0.0 2.0 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KNZ76534.1 - 0.07 12.7 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 KNZ76534.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 KNZ76534.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KNZ76534.1 - 0.16 10.6 0.0 0.92 8.1 0.0 2.1 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Rab5ip PF07019.12 KNZ76535.1 - 5.9 7.6 8.2 2 9.1 0.1 2.9 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) UQ_con PF00179.26 KNZ76536.1 - 9e-45 151.8 0.0 1.2e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNZ76536.1 - 0.00031 20.4 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KNZ76536.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.4 1 1 0 1 1 1 0 UEV domain zf-RING_2 PF13639.6 KNZ76537.1 - 1.2e-12 48.0 6.9 2e-12 47.2 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KNZ76537.1 - 1.1e-06 28.5 2.5 2.2e-06 27.6 2.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNZ76537.1 - 1.5e-06 28.0 4.5 2.6e-06 27.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KNZ76537.1 - 1.6e-06 28.3 4.6 3.5e-06 27.2 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KNZ76537.1 - 2.7e-06 27.1 2.9 4.4e-06 26.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ76537.1 - 5.4e-06 26.3 1.5 8.6e-06 25.6 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KNZ76537.1 - 9.4e-06 25.4 1.9 1.5e-05 24.8 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KNZ76537.1 - 9.8e-06 25.2 0.8 2.2e-05 24.1 0.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 KNZ76537.1 - 0.00065 19.7 1.1 0.0017 18.4 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KNZ76537.1 - 0.019 15.2 1.7 0.036 14.2 1.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KNZ76537.1 - 0.035 14.0 6.4 0.24 11.3 6.3 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KNZ76537.1 - 0.042 14.0 5.3 0.098 12.8 5.3 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 KNZ76537.1 - 0.078 12.8 2.4 0.14 12.0 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 KNZ76537.1 - 0.11 12.3 2.7 0.2 11.6 2.7 1.4 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 KNZ76537.1 - 0.31 10.7 4.0 0.65 9.7 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3915 PF13054.6 KNZ76537.1 - 1.3 9.0 5.0 0.45 10.5 1.6 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3915) P30 PF07390.11 KNZ76538.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Mycoplasma P30 protein Glyco_transf_90 PF05686.12 KNZ76540.1 - 8.3e-07 28.2 0.3 7.8e-05 21.8 0.0 3.0 3 1 0 3 3 3 2 Glycosyl transferase family 90 MtmB PF05369.12 KNZ76540.1 - 0.26 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Peptidase_A4 PF01828.17 KNZ76540.1 - 0.26 10.7 0.8 0.43 10.0 0.8 1.3 1 0 0 1 1 1 0 Peptidase A4 family Putative_PNPOx PF01243.20 KNZ76541.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase EBP PF05241.12 KNZ76542.1 - 0.00099 18.6 5.5 0.0012 18.3 5.5 1.2 1 0 0 1 1 1 1 Emopamil binding protein Trypan_PARP PF05887.11 KNZ76543.1 - 0.0031 17.5 1.3 0.004 17.1 1.3 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Bestrophin PF01062.21 KNZ76544.1 - 1.2e-36 126.7 5.7 2.3e-25 89.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel HGTP_anticodon PF03129.20 KNZ76545.1 - 1.3e-21 76.6 0.1 3.2e-21 75.3 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KNZ76545.1 - 7.2e-11 42.4 0.0 3.3e-10 40.2 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyoxalase_2 PF12681.7 KNZ76546.1 - 0.18 11.7 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Metallothio_Cad PF07846.11 KNZ76547.1 - 0.023 14.8 1.3 0.034 14.3 0.1 2.0 2 0 0 2 2 2 0 Metallothionein family STALD PF18185.1 KNZ76548.1 - 0.05 12.9 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family DUF1491 PF07372.12 KNZ76549.1 - 0.028 14.8 0.1 0.042 14.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1491) FAM209 PF15206.6 KNZ76549.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 FAM209 family DUF1287 PF06940.11 KNZ76550.1 - 0.71 9.5 3.3 0.23 11.1 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1287) DUF2235 PF09994.9 KNZ76553.1 - 0.014 14.7 0.1 0.025 13.9 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) GspH PF12019.8 KNZ76553.1 - 0.076 13.4 0.6 0.17 12.3 0.2 1.7 2 0 0 2 2 2 0 Type II transport protein GspH rve PF00665.26 KNZ76555.1 - 0.00018 21.7 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain POT1PC PF16686.5 KNZ76555.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Retrotrans_gag PF03732.17 KNZ76556.1 - 0.00061 20.0 2.0 0.0069 16.6 0.2 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein YqjK PF13997.6 KNZ76556.1 - 0.17 12.2 1.9 24 5.3 0.1 3.2 2 1 1 3 3 3 0 YqjK-like protein PI-PLC-X PF00388.19 KNZ76557.1 - 3.7e-52 175.8 0.0 6.2e-52 175.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KNZ76557.1 - 3.6e-42 143.3 0.1 6.5e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KNZ76557.1 - 2.4e-06 27.7 0.0 2.7e-05 24.4 0.0 2.5 1 1 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 KNZ76557.1 - 2.1e-05 24.9 0.1 7.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.6 KNZ76557.1 - 0.039 13.8 1.5 0.086 12.7 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 KNZ76557.1 - 0.06 12.9 0.0 16 5.3 0.0 2.9 2 0 0 2 2 2 0 EF hand FoP_duplication PF13865.6 KNZ76558.1 - 0.13 12.8 0.0 0.95 10.1 0.0 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Glyco_tranf_2_3 PF13641.6 KNZ76559.1 - 3.4e-30 105.6 0.0 4.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KNZ76559.1 - 1.4e-09 38.0 0.0 2.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KNZ76559.1 - 7.8e-09 35.2 0.1 3.2e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 KNZ76559.1 - 0.003 17.5 5.9 0.0054 16.7 5.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Creatinase_N_2 PF16189.5 KNZ76560.1 - 1.4e-38 132.5 0.0 1.7e-36 125.7 0.0 3.3 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KNZ76560.1 - 1.4e-26 93.5 0.0 1.8e-24 86.6 0.0 2.4 1 1 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KNZ76560.1 - 9.7e-22 76.8 0.6 2.2e-21 75.7 0.6 1.6 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KNZ76560.1 - 3.2e-17 63.4 0.1 2.3e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain NOG1_N PF17835.1 KNZ76561.1 - 1.3e-48 165.0 0.8 1.3e-48 165.0 0.8 1.8 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KNZ76561.1 - 4.3e-28 97.1 3.8 4.9e-28 96.9 2.4 1.9 1 1 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 KNZ76561.1 - 5.6e-27 93.3 0.0 1.2e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KNZ76561.1 - 1.8e-17 63.4 0.0 4.4e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ76561.1 - 1.7e-10 40.7 0.0 4e-10 39.4 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KNZ76561.1 - 0.00055 19.9 0.1 0.75 9.7 0.0 3.0 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 KNZ76561.1 - 0.0032 17.5 0.8 1.8 8.6 0.0 3.0 3 1 1 4 4 4 2 Dynamin family MMR_HSR1_Xtn PF16897.5 KNZ76561.1 - 0.0098 15.9 0.1 0.028 14.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 KNZ76561.1 - 0.018 15.4 0.1 0.67 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Sushi_2 PF09014.10 KNZ76561.1 - 0.055 13.4 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain LRR_4 PF12799.7 KNZ76563.1 - 0.066 13.7 3.7 9.5 6.8 0.8 4.3 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) G-alpha PF00503.20 KNZ76564.1 - 2.7e-82 276.8 0.0 3.3e-82 276.5 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ76564.1 - 7.1e-07 28.8 0.0 0.0055 16.2 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family NACHT PF05729.12 KNZ76564.1 - 0.05 13.5 0.1 0.43 10.5 0.0 2.4 3 0 0 3 3 3 0 NACHT domain TniB PF05621.11 KNZ76564.1 - 0.059 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 KNZ76564.1 - 0.13 12.5 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KNZ76564.1 - 0.13 11.6 0.0 0.65 9.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Collagen PF01391.18 KNZ76566.1 - 3.9e-09 36.1 32.5 3.9e-09 36.1 32.5 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) zinc_ribbon_16 PF17034.5 KNZ76567.1 - 2.8e-14 53.4 11.2 8.2e-14 51.9 11.2 1.8 1 1 0 1 1 1 1 Zinc-ribbon like family tRNA_lig_kinase PF08303.11 KNZ76567.1 - 0.18 11.9 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 tRNA ligase kinase domain WD40 PF00400.32 KNZ76567.1 - 0.64 11.0 12.8 17 6.5 0.2 5.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 KNZ76567.1 - 2.9 7.6 14.9 0.23 11.1 9.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Mut7-C PF01927.16 KNZ76567.1 - 3.2 7.9 5.5 17 5.5 0.3 2.3 1 1 1 2 2 2 0 Mut7-C RNAse domain Sugar_tr PF00083.24 KNZ76568.1 - 2.8e-97 326.4 25.6 4.9e-97 325.6 25.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ76568.1 - 1.4e-28 99.8 38.2 8.1e-17 61.2 9.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PSDC PF12588.8 KNZ76569.1 - 2.6e-42 144.1 0.1 7.1e-32 110.3 0.0 2.3 1 1 1 2 2 2 2 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 KNZ76569.1 - 2.4e-36 125.2 0.0 3.6e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF3682 PF12446.8 KNZ76573.1 - 0.075 13.5 3.6 0.11 13.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Chromo PF00385.24 KNZ76575.1 - 1.7e-17 63.0 0.1 2.2e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Terpene_synth_C PF03936.16 KNZ76577.1 - 6.7e-06 25.6 0.1 9.4e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF577 PF04510.12 KNZ76577.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF577) ABC2_membrane_4 PF12730.7 KNZ76578.1 - 8 6.4 16.6 11 5.9 16.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein IL34 PF15036.6 KNZ76580.1 - 0.057 13.5 0.2 0.064 13.3 0.2 1.1 1 0 0 1 1 1 0 Interleukin 34 PI-PLC-X PF00388.19 KNZ76581.1 - 1.3e-52 177.2 0.0 2.5e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KNZ76581.1 - 1.2e-38 132.0 0.1 4.2e-38 130.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KNZ76581.1 - 3.3e-08 33.7 0.0 9.8e-08 32.2 0.0 1.8 2 0 0 2 2 1 1 C2 domain EF-hand_7 PF13499.6 KNZ76581.1 - 2.1e-05 24.9 2.8 2.3e-05 24.7 1.3 1.9 2 0 0 2 2 2 1 EF-hand domain pair PH_14 PF17787.1 KNZ76581.1 - 0.00017 21.4 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 PH domain EF-hand_10 PF14788.6 KNZ76581.1 - 0.00062 19.6 2.1 0.0014 18.5 2.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_like PF09279.11 KNZ76581.1 - 0.00085 19.8 0.1 0.075 13.5 0.1 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 KNZ76581.1 - 0.0035 16.8 0.8 0.1 12.2 0.2 3.0 2 0 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 KNZ76581.1 - 0.033 14.1 0.3 0.091 12.7 0.3 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PH_12 PF16457.5 KNZ76581.1 - 0.082 13.4 0.5 0.34 11.4 0.0 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain EF-hand_6 PF13405.6 KNZ76581.1 - 0.088 12.8 4.3 0.3 11.1 0.7 3.3 3 0 0 3 3 3 0 EF-hand domain SEEEED PF14797.6 KNZ76581.1 - 5.2 7.2 19.3 11 6.2 1.8 2.4 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex IBR PF01485.21 KNZ76583.1 - 2.9e-17 62.6 21.4 1.7e-10 41.0 17.1 2.7 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain DUF3954 PF13128.6 KNZ76583.1 - 0.11 12.3 0.2 0.21 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) DUF2380 PF09533.10 KNZ76584.1 - 0.071 12.7 0.1 0.071 12.7 0.1 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) PC-Esterase PF13839.6 KNZ76586.1 - 2.2e-06 27.6 0.0 0.0057 16.4 0.0 2.1 2 0 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SPESP1 PF15754.5 KNZ76588.1 - 0.33 10.1 13.9 0.11 11.6 1.3 2.4 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 Ndc1_Nup PF09531.10 KNZ76588.1 - 2.3 6.8 5.5 3.7 6.1 5.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 KNZ76588.1 - 2.7 5.0 5.5 3.8 4.5 5.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp PF00026.23 KNZ76590.1 - 1.3e-65 221.9 0.2 1.3e-65 221.9 0.2 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ76590.1 - 6.2e-15 55.9 2.4 5.6e-09 36.5 0.2 3.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ76590.1 - 0.02 15.5 0.1 0.02 15.5 0.1 3.1 3 1 1 4 4 4 0 Aspartyl protease 7TM_GPCR_Sri PF10327.9 KNZ76591.1 - 0.025 13.8 0.1 0.034 13.3 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri DUF1512 PF07431.12 KNZ76591.1 - 0.17 10.8 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) gag-asp_proteas PF13975.6 KNZ76593.1 - 0.00043 20.8 0.0 0.00089 19.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76593.1 - 0.0007 20.2 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF3403 PF11883.8 KNZ76593.1 - 0.015 15.4 0.1 0.075 13.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) AbiEii PF08843.11 KNZ76594.1 - 0.089 12.7 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system TetR_C_13 PF16925.5 KNZ76595.1 - 0.011 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain TspO_MBR PF03073.15 KNZ76596.1 - 0.011 15.8 0.1 0.017 15.2 0.1 1.2 1 0 0 1 1 1 0 TspO/MBR family Dus PF01207.17 KNZ76597.1 - 1.3e-70 238.0 0.0 1.9e-70 237.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.14 KNZ76597.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 KNZ76597.1 - 0.0048 16.7 0.3 0.21 11.3 0.2 2.4 1 1 1 2 2 2 1 SOR/SNZ family Glyco_hydro_115 PF15979.5 KNZ76598.1 - 8.6e-140 466.0 2.3 1.2e-139 465.5 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KNZ76598.1 - 1.6e-53 181.1 0.0 2.7e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain RT_RNaseH PF17917.1 KNZ76602.1 - 4.1e-07 30.2 0.0 6.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76602.1 - 5e-05 23.3 0.0 8.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase ANAPC4_WD40 PF12894.7 KNZ76605.1 - 2.8e-11 43.6 2.0 0.022 15.0 0.1 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ76605.1 - 4.1e-07 30.6 9.6 0.29 12.1 0.1 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ELYS-bb PF16687.5 KNZ76605.1 - 0.01 14.5 0.0 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Nbas_N PF15492.6 KNZ76605.1 - 0.11 11.8 0.1 3.9 6.7 0.0 3.0 1 1 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KNZ76605.1 - 0.13 12.2 0.2 2 8.2 0.1 2.8 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A NUDIX PF00293.28 KNZ76606.1 - 2.1e-09 37.5 0.1 4.5e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 NUDIX domain adh_short_C2 PF13561.6 KNZ76609.1 - 6.8e-60 202.5 3.4 8.1e-60 202.3 3.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ76609.1 - 6.6e-54 182.3 1.0 9.7e-54 181.8 1.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ76609.1 - 5.2e-11 42.8 1.2 7.6e-11 42.3 1.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ76609.1 - 0.033 13.6 0.4 0.28 10.6 0.4 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ANAPC4_WD40 PF12894.7 KNZ76610.1 - 1.8e-09 37.8 0.1 0.00046 20.4 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ76610.1 - 5.2e-08 33.4 7.6 0.018 15.9 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat TFIIIC_delta PF12657.7 KNZ76610.1 - 0.062 13.2 0.3 0.47 10.3 0.0 2.2 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term HD PF01966.22 KNZ76613.1 - 4.2e-07 30.2 0.0 6.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 HD domain EF1_GNE PF00736.19 KNZ76615.1 - 1.5e-33 114.8 2.2 1.5e-33 114.8 2.2 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KNZ76615.1 - 1.4e-14 54.2 4.7 1.4e-14 54.2 4.7 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 KNZ76615.1 - 0.013 15.5 0.1 0.1 12.6 0.1 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ76615.1 - 0.054 13.7 0.3 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 KNZ76616.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like PHM7_cyt PF14703.6 KNZ76617.1 - 0.043 14.0 4.3 0.052 13.8 4.3 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Exonuc_VII_L PF02601.15 KNZ76617.1 - 0.13 11.8 5.3 0.15 11.6 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FemAB PF02388.16 KNZ76617.1 - 0.52 9.1 5.7 0.59 8.9 5.7 1.1 1 0 0 1 1 1 0 FemAB family GlutR_dimer PF00745.20 KNZ76617.1 - 0.59 10.6 10.4 0.3 11.6 5.1 2.3 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain FapA PF03961.13 KNZ76617.1 - 3.8 6.0 6.2 4.4 5.8 6.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF202 PF02656.15 KNZ76618.1 - 3.4e-05 24.2 1.8 3.4e-05 24.2 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1634 PF07843.11 KNZ76618.1 - 0.0057 16.7 0.1 0.0089 16.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1634) DUF4896 PF16237.5 KNZ76618.1 - 0.071 13.0 1.4 0.18 11.7 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4896) SdpI PF13630.6 KNZ76618.1 - 3.7 7.8 6.0 19 5.5 3.8 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family 60KD_IMP PF02096.20 KNZ76619.1 - 6.4e-23 81.5 1.3 8.4e-23 81.1 1.3 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Na_H_Exchanger PF00999.21 KNZ76620.1 - 3.6e-67 226.8 37.7 5.3e-60 203.2 27.0 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Tim17 PF02466.19 KNZ76620.1 - 0.0018 18.7 0.0 1.9 8.9 0.1 3.6 3 2 1 4 4 4 3 Tim17/Tim22/Tim23/Pmp24 family G-alpha PF00503.20 KNZ76621.1 - 4.4e-109 364.9 0.0 5.2e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ76621.1 - 6e-07 29.1 0.7 0.0014 18.1 0.1 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KNZ76621.1 - 0.0086 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Zeta_toxin PF06414.12 KNZ76621.1 - 0.077 12.3 0.2 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin Roc PF08477.13 KNZ76621.1 - 0.098 12.9 0.0 1.8 8.8 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KNZ76621.1 - 0.13 11.8 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain TMEM192 PF14802.6 KNZ76622.1 - 0.095 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 TMEM192 family His_Phos_1 PF00300.22 KNZ76624.1 - 0.00016 21.4 0.0 0.00019 21.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1077 PF06417.12 KNZ76624.1 - 0.18 11.9 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) gag-asp_proteas PF13975.6 KNZ76625.1 - 7.6e-06 26.4 0.0 1.8e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76625.1 - 2.6e-05 24.8 0.0 6.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF1198 PF06711.11 KNZ76627.1 - 0.06 13.4 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) PEMT PF04191.13 KNZ76631.1 - 1.9e-54 182.5 10.0 6.3e-31 106.9 1.5 2.5 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 KNZ76631.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KNZ76631.1 - 0.082 13.5 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 SKICH domain Aminotran_3 PF00202.21 KNZ76632.1 - 1.2e-102 343.6 0.0 3.6e-102 342.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KNZ76632.1 - 0.005 16.1 0.0 0.0087 15.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KNZ76632.1 - 0.012 14.9 0.0 0.14 11.4 0.0 2.1 1 1 0 1 1 1 0 Beta-eliminating lyase DHHC PF01529.20 KNZ76633.1 - 7.4e-33 113.5 7.2 7.4e-33 113.5 7.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DsbD_2 PF13386.6 KNZ76633.1 - 0.071 13.0 4.1 0.07 13.1 0.7 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein transmembrane region ATX_III PF08098.11 KNZ76633.1 - 0.18 11.9 2.9 0.39 10.8 2.9 1.5 1 0 0 1 1 1 0 Anemonia sulcata toxin III family HemY_N PF07219.13 KNZ76633.1 - 8.9 6.6 10.8 2 8.6 0.2 2.7 3 0 0 3 3 3 0 HemY protein N-terminus Cullin_binding PF03556.15 KNZ76634.1 - 1.5e-30 106.1 0.2 1e-20 74.4 0.0 2.3 2 0 0 2 2 2 2 Cullin binding UBA_4 PF14555.6 KNZ76634.1 - 4.7e-05 23.1 0.0 0.00013 21.7 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain RPS31 PF17067.5 KNZ76637.1 - 0.1 12.8 2.0 0.11 12.6 0.6 1.8 2 0 0 2 2 2 0 Ribosomal protein S31e PhoLip_ATPase_C PF16212.5 KNZ76638.1 - 2.4e-51 174.9 25.4 2.4e-51 174.9 25.4 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KNZ76638.1 - 3.4e-16 58.7 7.0 1e-15 57.2 7.0 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KNZ76638.1 - 8.5e-15 55.6 1.6 3.6e-09 37.2 0.7 2.6 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KNZ76638.1 - 1.7e-13 50.5 0.1 1.7e-13 50.5 0.1 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 KNZ76638.1 - 2.5e-08 33.9 0.0 6.9e-07 29.3 0.0 2.9 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KNZ76638.1 - 0.00036 20.3 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Herpes_Helicase PF02689.14 KNZ76639.1 - 1.4e-07 29.8 0.0 1.5e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ76639.1 - 0.0026 17.6 0.2 0.0073 16.1 0.2 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ76640.1 - 1.7e-32 113.0 0.1 1.9e-32 112.9 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ76640.1 - 0.023 14.4 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal PIF1 PF05970.14 KNZ76641.1 - 1.3e-07 31.1 0.0 1.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ76641.1 - 0.0021 18.5 0.0 0.003 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ76641.1 - 0.0032 17.5 0.0 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Med29 PF11568.8 KNZ76641.1 - 0.02 15.1 0.1 0.024 14.9 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 29 AAA_25 PF13481.6 KNZ76641.1 - 0.059 12.9 0.1 0.1 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2791 PF10923.8 KNZ76641.1 - 0.067 12.0 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Sdh5 PF03937.16 KNZ76641.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.3 1 1 0 1 1 1 0 Flavinator of succinate dehydrogenase Viral_helicase1 PF01443.18 KNZ76641.1 - 0.1 12.3 0.3 0.15 11.7 0.3 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ76641.1 - 0.13 12.7 0.0 0.95 9.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KNZ76641.1 - 0.16 12.4 1.0 7.2 7.1 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Helitron_like_N PF14214.6 KNZ76642.1 - 2.4e-58 197.5 0.4 2.4e-58 197.5 0.4 1.8 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ76642.1 - 0.0072 15.5 0.2 0.012 14.7 0.2 1.3 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) 2OG-FeII_Oxy_2 PF13532.6 KNZ76644.1 - 6.2e-09 36.3 0.0 2.1e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipase_GDSL PF00657.22 KNZ76646.1 - 2.3e-08 34.2 0.0 8.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KNZ76646.1 - 4.4e-06 27.2 0.2 3.9e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Ank_2 PF12796.7 KNZ76647.1 - 1e-36 125.4 1.0 2.6e-13 50.4 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) DHHC PF01529.20 KNZ76647.1 - 4.6e-31 107.7 10.1 4.6e-31 107.7 10.1 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 KNZ76647.1 - 1.1e-23 82.9 5.3 2.5e-10 40.4 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KNZ76647.1 - 8.7e-22 76.6 3.9 0.00013 22.2 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KNZ76647.1 - 1.7e-21 76.3 3.8 9.2e-08 32.5 0.0 5.5 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ76647.1 - 6.9e-21 72.1 2.6 0.00038 20.7 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeat PocR PF10114.9 KNZ76647.1 - 0.24 11.2 1.2 0.41 10.4 1.2 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR YfhO PF09586.10 KNZ76647.1 - 2.3 6.3 8.3 4.7 5.3 8.3 1.4 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABA_GPCR PF12430.8 KNZ76649.1 - 2.4e-39 134.9 4.3 2.4e-39 134.9 4.3 3.3 2 1 1 3 3 3 2 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KNZ76649.1 - 5.8e-15 55.1 0.0 1.4e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Heliorhodopsin PF18761.1 KNZ76649.1 - 0.053 12.8 0.2 0.053 12.8 0.2 2.1 2 0 0 2 2 2 0 Heliorhodopsin EF1G PF00647.19 KNZ76650.1 - 6.9e-41 138.6 0.0 1.1e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KNZ76650.1 - 8.7e-12 45.1 0.4 3.6e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KNZ76650.1 - 1.1e-09 38.5 0.0 4.1e-09 36.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ76650.1 - 4.5e-08 33.0 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ76650.1 - 5.1e-07 29.8 0.0 2.6e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KNZ76650.1 - 6.8e-07 29.6 0.0 1.6e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ76650.1 - 0.00021 21.5 0.0 0.00077 19.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KNZ76650.1 - 0.0068 16.2 0.0 0.026 14.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ribosomal_60s PF00428.19 KNZ76650.1 - 0.064 13.9 3.4 0.14 12.7 3.4 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein OAD_gamma PF04277.13 KNZ76650.1 - 3 8.5 6.3 5.7 7.6 6.3 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain HNH_2 PF13391.6 KNZ76652.1 - 1.3e-06 28.4 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.6 KNZ76653.1 - 2.1e-05 24.6 0.0 3.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Inhibitor_I48 PF10467.9 KNZ76653.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor clitocypin GGDEF_2 PF17853.1 KNZ76654.1 - 0.046 14.0 1.0 7.4 6.9 0.2 2.6 2 0 0 2 2 2 0 GGDEF-like domain NMDAR2_C PF10565.9 KNZ76654.1 - 0.23 10.3 1.6 0.38 9.6 1.6 1.3 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF3716 PF12511.8 KNZ76654.1 - 0.38 10.8 5.2 0.11 12.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) gag-asp_proteas PF13975.6 KNZ76655.1 - 3.3e-08 34.0 0.0 5.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ76655.1 - 1.9e-07 31.6 0.0 4.2e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KNZ76655.1 - 8.2e-05 22.4 0.1 0.00011 21.9 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KNZ76655.1 - 0.063 12.8 0.1 0.079 12.5 0.1 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase Striatin PF08232.12 KNZ76656.1 - 0.11 13.1 0.3 0.11 13.1 0.3 1.9 2 0 0 2 2 2 0 Striatin family Fmp27_WPPW PF10359.9 KNZ76656.1 - 0.21 10.4 2.4 0.97 8.2 0.5 2.0 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain EloA-BP1 PF15870.5 KNZ76657.1 - 0.22 11.8 5.7 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 ElonginA binding-protein 1 CPSF73-100_C PF11718.8 KNZ76659.1 - 4.7e-68 229.0 0.2 8.2e-68 228.2 0.2 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KNZ76659.1 - 2e-29 102.1 0.0 4.7e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 KNZ76659.1 - 4.8e-18 65.3 0.0 9.8e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 KNZ76659.1 - 1.4e-17 64.3 0.2 1.4e-17 64.3 0.2 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 KNZ76659.1 - 2.7e-16 59.2 0.2 6e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KNZ76659.1 - 4.2e-08 33.0 0.5 2.3e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KNZ76659.1 - 1.9e-07 31.1 1.2 4.1e-06 26.8 0.0 3.3 3 1 0 3 3 3 1 Beta-lactamase superfamily domain ECF_trnsprt PF12822.7 KNZ76660.1 - 0.012 15.7 9.9 0.29 11.2 9.7 2.0 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Mcl1_mid PF12341.8 KNZ76661.1 - 4.4e-88 295.5 0.0 1.7e-87 293.6 0.0 1.9 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KNZ76661.1 - 5e-16 58.8 15.3 7.7e-06 26.5 0.1 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ76661.1 - 1.8e-09 37.8 0.5 0.013 15.7 0.0 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain tRNA_lig_CPD PF08302.11 KNZ76662.1 - 0.11 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain M64_N PF16217.5 KNZ76662.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M64 N-terminus Asp_protease_2 PF13650.6 KNZ76663.1 - 2.7e-05 24.7 0.0 4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ76663.1 - 9.7e-05 22.9 0.0 0.00012 22.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RT_RNaseH PF17917.1 KNZ76664.1 - 1.5e-11 44.5 0.0 1.8e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76664.1 - 1.1e-09 38.2 0.0 1.4e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1919 PF08942.10 KNZ76664.1 - 0.025 14.1 0.1 0.035 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) ARF7EP_C PF14949.6 KNZ76664.1 - 0.043 14.4 2.9 0.069 13.8 2.9 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Terpene_synth_C PF03936.16 KNZ76665.1 - 6.2e-05 22.5 0.0 8.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RrnaAD PF00398.20 KNZ76666.1 - 5.6e-19 68.2 0.0 1.1e-18 67.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF515 PF04415.12 KNZ76667.1 - 4 5.7 4.3 7.8 4.8 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Terpene_synth_C PF03936.16 KNZ76668.1 - 2.3e-07 30.4 0.1 1.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Helitron_like_N PF14214.6 KNZ76669.1 - 1.3e-63 214.7 0.1 2e-63 214.1 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MitMem_reg PF13012.6 KNZ76670.1 - 0.028 14.9 0.0 0.029 14.8 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ76671.1 - 2.9e-104 349.1 0.0 3.4e-104 348.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76671.1 - 4.3e-08 33.1 0.0 6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ76671.1 - 0.013 15.5 0.0 0.044 13.8 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ76671.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain 4HPAD_g_N PF18671.1 KNZ76671.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Viral_helicase1 PF01443.18 KNZ76671.1 - 0.17 11.6 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zf-HIT PF04438.16 KNZ76676.1 - 6.2e-07 29.2 11.9 1.1e-06 28.4 11.9 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KNZ76676.1 - 1.2 9.3 13.0 2.1 8.5 13.0 1.4 1 0 0 1 1 1 0 MYND finger HSP70 PF00012.20 KNZ76677.1 - 1.1e-161 539.0 0.1 2.4e-161 538.0 0.1 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KNZ76677.1 - 8e-10 38.0 0.0 1.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein LSM PF01423.22 KNZ76678.1 - 1.1e-07 31.5 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF747 PF05346.11 KNZ76679.1 - 2.7e-113 378.7 6.9 3.4e-113 378.3 6.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family TetR_C_12 PF16914.5 KNZ76679.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal AAA_22 PF13401.6 KNZ76681.1 - 3.9e-13 49.8 0.0 8.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ76681.1 - 2.9e-12 47.3 0.0 1e-10 42.3 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 KNZ76681.1 - 2.2e-09 37.8 0.0 6.1e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KNZ76681.1 - 4.5e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 KNZ76681.1 - 6.4e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein KAP_NTPase PF07693.14 KNZ76681.1 - 0.00038 19.8 0.0 0.029 13.6 0.0 2.2 1 1 0 2 2 2 1 KAP family P-loop domain NACHT PF05729.12 KNZ76681.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 KNZ76681.1 - 0.0036 16.8 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 KNZ76681.1 - 0.0068 16.7 0.0 0.023 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cdc6_C PF09079.11 KNZ76681.1 - 0.013 15.5 0.0 0.04 13.9 0.0 1.8 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain NB-ARC PF00931.22 KNZ76681.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 KNZ76681.1 - 0.022 13.8 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TIP49 PF06068.13 KNZ76681.1 - 0.025 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 KNZ76681.1 - 0.029 14.4 0.0 0.095 12.7 0.0 1.9 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KNZ76681.1 - 0.031 13.8 0.1 0.089 12.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 KNZ76681.1 - 0.037 13.3 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 KNZ76681.1 - 0.038 13.9 0.0 0.15 11.9 0.0 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 KNZ76681.1 - 0.049 13.3 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 KNZ76681.1 - 0.066 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 KNZ76681.1 - 0.13 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 KNZ76681.1 - 0.15 11.7 0.0 1 9.1 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KNZ76681.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.8 1 1 0 1 1 1 0 RNA helicase TP6A_N PF04406.14 KNZ76682.1 - 2.2e-20 72.4 0.3 7e-20 70.8 0.4 1.7 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF3435 PF11917.8 KNZ76684.1 - 0.085 11.8 4.5 0.13 11.1 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) LUC7 PF03194.15 KNZ76684.1 - 0.14 11.8 1.3 0.21 11.2 1.3 1.3 1 0 0 1 1 1 0 LUC7 N_terminus ARL6IP6 PF15062.6 KNZ76684.1 - 0.28 11.3 0.7 0.67 10.1 0.7 1.6 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix DUF4294 PF14127.6 KNZ76684.1 - 0.38 10.7 2.2 0.94 9.4 1.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4294) HK PF02110.15 KNZ76685.1 - 1.2e-70 237.8 0.4 1.2e-70 237.8 0.4 1.9 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KNZ76685.1 - 7.5e-53 178.5 0.7 3.7e-52 176.3 0.3 2.1 2 0 0 2 2 2 1 Thiamine monophosphate synthase SUR7 PF06687.12 KNZ76686.1 - 3.5e-17 62.7 9.4 1.1e-16 61.1 9.4 1.8 1 1 0 1 1 1 1 SUR7/PalI family Oxidored_q2 PF00420.24 KNZ76686.1 - 0.018 14.6 3.9 0.35 10.5 0.4 2.5 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2628 PF10947.8 KNZ76686.1 - 2.6 8.5 4.9 1.2 9.5 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF4293 PF14126.6 KNZ76688.1 - 6.4 7.0 13.5 0.32 11.2 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) APH PF01636.23 KNZ76689.1 - 5.3e-12 46.2 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KNZ76689.1 - 3.6e-07 29.4 0.0 0.0022 16.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Pkinase PF00069.25 KNZ76689.1 - 0.051 12.9 0.3 0.39 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein kinase domain RIO1 PF01163.22 KNZ76689.1 - 0.091 12.4 0.0 0.97 9.0 0.0 2.7 4 0 0 4 4 4 0 RIO1 family Lyase_8 PF02278.18 KNZ76691.1 - 1.9e-62 211.1 2.2 1.9e-62 211.1 2.2 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.11 KNZ76691.1 - 6.6e-14 51.6 0.3 1.4e-13 50.5 0.3 1.4 1 1 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain Lyase_8_C PF02884.17 KNZ76691.1 - 4.4e-07 30.3 0.3 1e-06 29.1 0.3 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 8, C-terminal beta-sandwich domain F-box-like PF12937.7 KNZ76692.1 - 2.4e-08 33.8 3.1 9.3e-08 31.9 0.8 3.0 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ76692.1 - 0.48 10.4 2.4 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 F-box domain Pro_CA PF00484.19 KNZ76693.1 - 6.3e-31 107.8 0.1 1.5e-30 106.6 0.1 1.6 1 1 0 1 1 1 1 Carbonic anhydrase Retrotran_gag_2 PF14223.6 KNZ76695.1 - 4.3e-15 55.6 0.0 5.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KNZ76695.1 - 1.2e-07 31.2 0.4 2.2e-07 30.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KNZ76695.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PRMT5_TIM PF17285.2 KNZ76695.1 - 0.063 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 PRMT5 TIM barrel domain RNase_PH PF01138.21 KNZ76697.1 - 1.7e-15 57.7 1.7 3.9e-15 56.5 1.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 ABC_tran PF00005.27 KNZ76698.1 - 3.6e-29 102.0 0.0 2e-14 54.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KNZ76698.1 - 4.3e-08 33.3 1.6 0.00054 19.9 0.3 3.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KNZ76698.1 - 0.00034 20.3 0.1 0.06 13.1 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Ploopntkinase1 PF18748.1 KNZ76698.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 SbcCD_C PF13558.6 KNZ76698.1 - 0.018 15.2 0.0 0.6 10.4 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.8 KNZ76698.1 - 0.054 11.0 0.0 0.071 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FANC_SAP PF18081.1 KNZ76698.1 - 0.16 12.1 2.9 2.5 8.3 1.8 3.1 3 0 0 3 3 3 0 Fanconi anemia-associated nuclease SAP domain RsgA_GTPase PF03193.16 KNZ76698.1 - 0.16 11.8 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KNZ76698.1 - 0.27 10.4 0.1 33 3.6 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain SH3_11 PF18103.1 KNZ76700.1 - 0.053 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain ANAPC10 PF03256.16 KNZ76701.1 - 1.3e-47 161.9 0.0 1.5e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 KNZ76701.1 - 0.035 14.2 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 F5/8 type C domain SIR2 PF02146.17 KNZ76702.1 - 2e-28 99.5 0.0 9.9e-28 97.3 0.0 2.1 1 1 0 1 1 1 1 Sir2 family Sacchrp_dh_NADP PF03435.18 KNZ76702.1 - 2.3e-18 66.7 0.0 4.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 KNZ76702.1 - 2e-07 31.1 0.0 5.8e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KNZ76702.1 - 7.7e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KNZ76702.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KNZ76702.1 - 0.0013 18.2 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 KNZ76702.1 - 0.0013 18.2 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ76702.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 KNZ76702.1 - 0.0057 17.1 0.0 0.015 15.8 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KNZ76702.1 - 0.044 13.2 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CBM_1 PF00734.18 KNZ76702.1 - 1.1 9.2 4.3 9.2 6.3 1.6 2.5 2 0 0 2 2 2 0 Fungal cellulose binding domain APH PF01636.23 KNZ76704.1 - 2.7e-07 30.8 0.1 2e-06 27.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ76704.1 - 4.9e-05 22.8 0.0 6.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ76704.1 - 0.00094 18.8 0.0 0.004 16.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 KNZ76704.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AbiEii PF08843.11 KNZ76707.1 - 4e-07 30.2 0.0 5.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system AbiEi_1 PF09407.10 KNZ76707.1 - 0.086 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain DUF2204 PF09970.9 KNZ76707.1 - 0.22 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) LRR_4 PF12799.7 KNZ76708.1 - 0.0036 17.7 0.2 2.7 8.6 0.0 4.6 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) DUF5584 PF17822.1 KNZ76712.1 - 0.024 14.1 0.4 5.4 6.4 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5584) Sod_Cu PF00080.20 KNZ76715.1 - 2.9e-07 30.7 1.7 1.3e-06 28.6 1.6 1.8 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Integrase_H2C2 PF17921.1 KNZ76715.1 - 1.9e-05 24.7 0.9 2.8e-05 24.1 0.9 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Prok-JAB PF14464.6 KNZ76715.1 - 0.072 12.9 0.1 0.085 12.6 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain GH131_N PF18271.1 KNZ76716.1 - 6e-58 196.5 2.8 1e-57 195.8 2.8 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KNZ76716.1 - 3.7e-09 36.4 9.9 3.7e-09 36.4 9.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain RSN1_7TM PF02714.15 KNZ76717.1 - 5.3e-32 111.2 15.2 5.3e-32 111.2 15.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KNZ76717.1 - 7e-18 65.5 0.0 6.2e-12 46.1 0.0 3.1 2 1 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KNZ76717.1 - 5.5e-16 58.7 1.9 5.5e-16 58.7 1.9 2.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KNZ76717.1 - 0.043 14.0 0.2 0.12 12.6 0.2 1.7 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter Peptidase_S9 PF00326.21 KNZ76718.1 - 1.2e-48 165.4 0.4 1.8e-48 164.8 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KNZ76718.1 - 1.9e-06 27.7 0.3 0.021 14.5 0.1 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 KNZ76718.1 - 0.11 11.1 0.0 8.1 5.0 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF3515 PF12028.8 KNZ76718.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) RL10P_insert PF17777.1 KNZ76719.1 - 9.9e-22 76.7 0.0 1.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 KNZ76719.1 - 5.1e-21 74.7 0.0 6.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RRF PF01765.19 KNZ76719.1 - 0.086 12.8 0.1 0.21 11.5 0.3 1.5 2 0 0 2 2 2 0 Ribosome recycling factor Tautomerase_2 PF14552.6 KNZ76719.1 - 0.16 12.1 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Tautomerase enzyme HEAT_2 PF13646.6 KNZ76720.1 - 6.3e-41 138.7 0.3 2.1e-14 53.6 0.1 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 KNZ76720.1 - 4.2e-22 76.5 0.0 0.00044 20.6 0.0 6.5 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 KNZ76720.1 - 3.9e-12 45.3 0.2 0.009 16.2 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KNZ76720.1 - 7.6e-06 26.3 1.7 1.2 9.7 0.0 5.2 5 1 1 6 6 6 2 HEAT-like repeat Arm PF00514.23 KNZ76720.1 - 0.00016 21.6 0.0 0.57 10.3 0.0 3.3 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KNZ76720.1 - 0.014 15.4 0.0 0.76 9.8 0.0 3.2 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KNZ76720.1 - 0.16 11.8 0.0 0.69 9.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) GlutR_dimer PF00745.20 KNZ76720.1 - 0.17 12.3 0.3 5.7 7.4 0.1 2.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain RNase_H PF00075.24 KNZ76721.1 - 0.0015 18.7 0.3 0.0027 17.9 0.3 1.4 1 0 0 1 1 1 1 RNase H F-box-like PF12937.7 KNZ76722.1 - 6.1e-11 42.0 1.3 1.7e-10 40.6 1.3 1.8 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.28 KNZ76722.1 - 2.7e-06 26.9 0.1 0.0046 16.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ76722.1 - 0.00011 22.0 0.1 0.45 10.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ76722.1 - 0.054 14.3 1.6 0.13 13.1 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_1 PF00560.33 KNZ76722.1 - 0.24 12.1 3.8 15 6.6 0.4 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat CDC37_N PF03234.14 KNZ76723.1 - 1.7e-32 113.1 1.8 2.3e-31 109.4 0.0 2.7 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KNZ76723.1 - 4e-32 110.6 0.0 8.5e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KNZ76723.1 - 8.4e-19 67.6 0.1 8.4e-19 67.6 0.1 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain CR6_interact PF10147.9 KNZ76723.1 - 0.53 10.0 4.6 1.3 8.8 4.6 1.7 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Adaptin_binding PF10199.9 KNZ76724.1 - 1.5e-10 41.7 0.9 2.9e-09 37.6 0.9 2.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Methyltransf_25 PF13649.6 KNZ76725.1 - 1.3e-16 61.1 0.0 2.9e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ76725.1 - 2e-12 47.6 0.0 5.2e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ76725.1 - 3.8e-10 39.8 0.0 7.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ76725.1 - 8.4e-09 35.4 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ76725.1 - 4.9e-08 32.6 0.0 8.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KNZ76725.1 - 0.0002 22.1 0.0 0.00052 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KNZ76725.1 - 0.0047 16.2 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_29 PF03141.16 KNZ76725.1 - 0.027 13.0 0.0 0.048 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 KNZ76725.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase Zap1_zf2 PF18217.1 KNZ76725.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Zap1 zinc finger 2 MTS PF05175.14 KNZ76725.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KNZ76725.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 KNZ76725.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 KNZ76725.1 - 0.21 11.1 0.0 0.46 9.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.20 KNZ76725.1 - 0.23 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase adh_short PF00106.25 KNZ76726.1 - 7.9e-34 116.8 0.0 1.2e-27 96.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ76726.1 - 1.1e-20 74.3 0.0 4.5e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ76726.1 - 2.3e-07 30.9 0.0 3.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ76726.1 - 0.00046 19.7 0.1 0.00068 19.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KNZ76726.1 - 0.0013 19.0 0.1 0.0024 18.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KNZ76726.1 - 0.017 15.1 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KNZ76726.1 - 0.019 14.4 0.1 0.18 11.1 0.1 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KNZ76726.1 - 0.062 13.2 0.1 0.09 12.7 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KNZ76726.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 KNZ76726.1 - 0.16 11.3 0.1 0.29 10.4 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pox_A_type_inc PF04508.12 KNZ76727.1 - 7.4 6.6 7.9 0.42 10.5 1.5 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SRF-TF PF00319.18 KNZ76728.1 - 4.9e-21 74.0 1.2 6.1e-21 73.6 0.1 1.7 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Cytochrom_B558a PF05038.13 KNZ76728.1 - 0.36 10.4 2.0 0.27 10.8 0.2 1.6 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit adh_short PF00106.25 KNZ76729.1 - 3.3e-29 101.8 0.1 1.6e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ76729.1 - 3.2e-19 69.4 0.0 1.8e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ76729.1 - 3.6e-08 33.5 0.0 5.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ76729.1 - 7.3e-06 25.6 0.2 1.3e-05 24.8 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ76729.1 - 0.0012 18.8 0.2 0.0018 18.2 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding QRPTase_C PF01729.19 KNZ76729.1 - 0.0035 17.1 0.1 0.02 14.6 0.0 2.1 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain GDP_Man_Dehyd PF16363.5 KNZ76729.1 - 0.047 13.1 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KNZ76729.1 - 0.14 11.4 0.0 0.64 9.1 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein NicO PF03824.16 KNZ76730.1 - 1.3e-24 87.0 0.1 1.3e-24 87.0 0.1 3.1 3 2 0 3 3 3 2 High-affinity nickel-transport protein MBOAT_2 PF13813.6 KNZ76731.1 - 4.5e-14 52.5 3.8 1.7e-13 50.7 1.0 2.5 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Hpt PF01627.23 KNZ76732.1 - 6.2e-12 45.6 0.5 8.3e-12 45.2 0.5 1.2 1 0 0 1 1 1 1 Hpt domain NCA2 PF08637.10 KNZ76733.1 - 8.8e-79 264.7 0.0 1.9e-78 263.6 0.0 1.5 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Mod_r PF07200.13 KNZ76734.1 - 6.8e-40 136.5 7.0 1.2e-39 135.7 7.0 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Rootletin PF15035.6 KNZ76734.1 - 0.00065 19.8 3.5 0.0011 19.0 3.5 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion LRS4 PF10422.9 KNZ76734.1 - 0.0036 16.9 1.3 0.0044 16.6 1.3 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Ufd2P_core PF10408.9 KNZ76734.1 - 0.0045 15.7 0.5 0.0053 15.4 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core DUF5638 PF18688.1 KNZ76734.1 - 0.048 14.0 2.1 0.78 10.1 1.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Syntaxin-6_N PF09177.11 KNZ76734.1 - 0.068 13.7 1.2 0.91 10.1 0.6 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal KH_6 PF15985.5 KNZ76735.1 - 6.7e-14 52.0 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KNZ76735.1 - 3.8e-13 49.1 0.9 7e-13 48.3 0.9 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain NuA4 PF09340.10 KNZ76736.1 - 5.1e-17 61.5 6.8 2.9e-16 59.1 6.8 2.0 1 1 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF4294 PF14127.6 KNZ76736.1 - 0.1 12.5 1.1 0.11 12.4 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) AAA PF00004.29 KNZ76737.1 - 1.4e-38 132.3 0.0 2.8e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KNZ76737.1 - 2.2e-19 69.1 0.1 4.7e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KNZ76737.1 - 2.3e-10 40.1 0.2 5.2e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KNZ76737.1 - 4.2e-05 24.0 0.3 0.012 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KNZ76737.1 - 0.00086 19.3 0.0 0.0053 16.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNZ76737.1 - 0.0011 19.1 0.0 0.011 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KNZ76737.1 - 0.0023 17.7 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KNZ76737.1 - 0.0055 17.0 1.2 0.3 11.4 0.1 3.0 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 KNZ76737.1 - 0.013 14.9 0.2 0.045 13.1 0.0 1.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KNZ76737.1 - 0.021 15.0 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KNZ76737.1 - 0.023 14.5 0.3 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KNZ76737.1 - 0.03 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1640 PF07798.11 KNZ76737.1 - 0.04 14.0 0.5 0.077 13.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) PhoH PF02562.16 KNZ76737.1 - 0.046 13.2 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KNZ76737.1 - 0.21 11.3 1.3 0.34 10.6 0.1 2.0 3 1 0 3 3 3 0 AAA domain XhlA PF10779.9 KNZ76737.1 - 0.41 10.9 5.4 6.5 7.0 3.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA JIP_LZII PF16471.5 KNZ76737.1 - 0.5 10.6 7.2 0.08 13.1 3.2 1.8 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II ETC_C1_NDUFA4 PF04800.12 KNZ76738.1 - 6.4e-32 109.7 0.1 8.6e-32 109.3 0.1 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region RICTOR_N PF14664.6 KNZ76739.1 - 1.3e-118 396.3 0.1 3.7e-118 394.7 0.0 1.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 KNZ76739.1 - 2.9e-41 139.4 0.4 8.1e-38 128.4 0.0 4.0 3 1 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 KNZ76739.1 - 7.5e-35 119.6 0.1 7.6e-34 116.4 0.0 2.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 KNZ76739.1 - 6.5e-31 106.4 0.0 1.1e-27 96.1 0.0 4.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KNZ76739.1 - 1.7e-05 24.8 8.4 5.2e-05 23.3 8.4 1.9 1 0 0 1 1 1 1 Hr1 repeat HEAT PF02985.22 KNZ76739.1 - 7.7e-05 22.6 0.1 7.3 7.1 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Ribosomal_L22 PF00237.19 KNZ76740.1 - 3.5e-35 120.3 0.1 5.1e-35 119.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Asp_Glu_race_2 PF14669.6 KNZ76740.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase RasGEF_N PF00618.20 KNZ76741.1 - 2.9e-12 46.8 0.7 4.7e-12 46.1 0.7 1.4 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 KNZ76741.1 - 5.9e-07 29.9 0.6 1.1e-06 29.0 0.6 1.4 1 0 0 1 1 1 1 RasGEF domain HECT PF00632.25 KNZ76742.1 - 3e-95 319.2 0.0 4.1e-95 318.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KNZ76742.1 - 7e-35 118.8 11.7 3.3e-11 43.1 0.3 4.2 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KNZ76742.1 - 5.1e-16 58.8 0.0 1.2e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 KNZ76742.1 - 0.32 10.9 7.9 0.49 10.3 7.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KNZ76742.1 - 4.5 5.4 6.9 6.4 4.9 6.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_Tnp_4 PF13359.6 KNZ76743.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Eaf7 PF07904.13 KNZ76745.1 - 1.2e-18 67.4 0.0 1.9e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 K1377 PF15352.6 KNZ76745.1 - 0.093 11.0 0.1 0.11 10.7 0.1 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Ufd2P_core PF10408.9 KNZ76746.1 - 7.9e-212 705.3 3.3 9.4e-212 705.0 3.3 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core PSD5 PF07637.11 KNZ76746.1 - 0.028 14.8 0.1 5.2 7.5 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) RIG-I_C PF18119.1 KNZ76746.1 - 0.07 13.1 1.3 0.11 12.5 0.3 1.8 2 0 0 2 2 2 0 RIG-I receptor C-terminal domain Ribosomal_L35p PF01632.19 KNZ76747.1 - 2.9e-18 66.1 5.3 3.9e-18 65.7 5.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 His_Phos_1 PF00300.22 KNZ76748.1 - 1.1e-30 106.8 0.0 2.1e-30 105.9 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PhoU_div PF01865.16 KNZ76748.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF47 zf-AN1 PF01428.16 KNZ76749.1 - 9.5e-19 67.3 33.0 4.1e-10 39.7 8.1 3.0 3 0 0 3 3 3 2 AN1-like Zinc finger DUF753 PF05444.12 KNZ76749.1 - 0.027 14.5 10.5 0.93 9.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF753) Transp_Tc5_C PF04236.15 KNZ76749.1 - 0.056 13.8 19.6 0.21 12.0 8.2 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain SR-25 PF10500.9 KNZ76749.1 - 1.4 8.4 12.7 2.1 7.9 12.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pro_isomerase PF00160.21 KNZ76750.1 - 1.4e-49 168.4 0.5 2.9e-49 167.4 0.5 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KNZ76750.1 - 2e-09 37.9 0.9 0.0057 17.5 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ76750.1 - 0.15 12.4 0.0 6.7 7.1 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4504 PF14953.6 KNZ76751.1 - 0.0052 16.2 0.1 0.021 14.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4504) Nuc_sug_transp PF04142.15 KNZ76752.1 - 0.036 13.2 0.2 0.041 13.0 0.2 1.0 1 0 0 1 1 1 0 Nucleotide-sugar transporter BTP PF05232.12 KNZ76752.1 - 0.045 13.8 1.5 0.069 13.2 1.5 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter RIO1 PF01163.22 KNZ76753.1 - 5.5e-70 234.8 1.4 5.9e-70 234.7 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KNZ76753.1 - 0.00061 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ76753.1 - 0.00083 19.3 1.2 1.2 9.0 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KNZ76753.1 - 0.004 16.6 1.9 0.98 8.7 0.6 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family ILVD_EDD PF00920.21 KNZ76754.1 - 7.8e-196 651.7 0.0 1e-195 651.3 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Septin PF00735.18 KNZ76755.1 - 2.8e-30 105.6 0.0 4.2e-10 39.4 0.0 3.2 3 0 0 3 3 3 3 Septin Zn_clus PF00172.18 KNZ76755.1 - 5.9e-19 67.9 27.3 2.6e-09 37.0 7.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.18 KNZ76756.1 - 1.7e-47 162.1 0.1 5.7e-19 68.5 0.0 3.2 3 0 0 3 3 3 3 Septin GTP_EFTU PF00009.27 KNZ76756.1 - 0.00013 21.6 0.2 0.00097 18.7 0.0 2.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNZ76756.1 - 0.00019 21.5 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KNZ76756.1 - 0.0017 18.6 0.0 0.027 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ76756.1 - 0.017 15.5 0.1 0.036 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KNZ76756.1 - 0.098 13.2 0.0 0.3 11.6 0.0 2.0 1 1 0 1 1 1 0 ABC transporter Ribosomal_L2_C PF03947.18 KNZ76757.1 - 5e-54 181.9 0.7 1.1e-53 180.8 0.7 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KNZ76757.1 - 8.6e-24 83.3 0.4 1.6e-23 82.4 0.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain CM_2 PF01817.21 KNZ76758.1 - 1.2e-05 25.6 0.0 0.013 15.8 0.0 2.6 2 0 0 2 2 2 2 Chorismate mutase type II Nas2_N PF18265.1 KNZ76759.1 - 2.7e-19 68.9 0.1 3.8e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 KNZ76759.1 - 3.9e-07 29.8 0.0 1e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 KNZ76759.1 - 1.2e-06 28.8 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KNZ76759.1 - 1.9e-06 28.3 0.0 3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KNZ76759.1 - 0.082 13.3 0.0 0.12 12.7 0.0 1.4 1 1 0 1 1 1 0 PDZ domain Thi4 PF01946.17 KNZ76760.1 - 1.7e-99 331.9 0.1 2e-99 331.6 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KNZ76760.1 - 7.7e-10 38.9 1.1 2.4e-08 34.0 0.6 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KNZ76760.1 - 3.7e-07 29.5 0.2 1.7e-06 27.3 0.2 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ76760.1 - 1.9e-06 28.0 0.1 4.7e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KNZ76760.1 - 3e-06 26.7 0.0 3.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ76760.1 - 3.5e-06 26.4 1.5 0.00033 19.9 0.3 2.4 2 1 1 3 3 3 2 FAD binding domain NAD_binding_9 PF13454.6 KNZ76760.1 - 7.3e-05 22.8 0.1 0.00017 21.6 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KNZ76760.1 - 0.00031 20.2 0.1 0.00049 19.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KNZ76760.1 - 0.00039 19.3 0.2 0.00074 18.3 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KNZ76760.1 - 0.00058 19.1 0.1 0.0029 16.8 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KNZ76760.1 - 0.029 13.6 0.1 0.062 12.5 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KNZ76760.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 KNZ76760.1 - 0.098 11.5 0.3 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KNZ76760.1 - 0.24 10.5 0.0 0.4 9.8 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-RVT PF13966.6 KNZ76764.1 - 0.00029 21.5 0.5 0.00087 20.0 0.5 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ76764.1 - 0.024 14.6 0.3 0.046 13.7 0.3 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Retrotran_gag_2 PF14223.6 KNZ76766.1 - 9.1e-11 41.6 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ76766.1 - 0.0034 17.1 0.7 0.0074 16.0 0.7 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger eIF3g PF12353.8 KNZ76766.1 - 0.044 14.2 0.8 0.075 13.4 0.8 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Vps36-NZF-N PF16988.5 KNZ76766.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Mitofilin PF09731.9 KNZ76767.1 - 1.7e-53 182.5 7.1 1.9e-53 182.3 7.1 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2927 PF11150.8 KNZ76767.1 - 0.018 15.1 0.6 0.023 14.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) DUF4795 PF16043.5 KNZ76767.1 - 0.022 14.3 6.4 0.12 12.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) MnmE_helical PF12631.7 KNZ76767.1 - 0.3 11.2 2.1 0.4 10.8 2.1 1.2 1 0 0 1 1 1 0 MnmE helical domain MFS_1 PF07690.16 KNZ76770.1 - 3.9e-35 121.4 42.6 7.4e-35 120.5 42.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ76770.1 - 4.6e-11 42.2 13.7 4.6e-11 42.2 13.7 3.2 2 2 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KNZ76770.1 - 0.0013 17.3 11.2 0.0013 17.3 11.2 1.5 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ThylakoidFormat PF11264.8 KNZ76771.1 - 0.0027 17.4 0.0 0.0033 17.2 0.0 1.2 1 0 0 1 1 1 1 Thylakoid formation protein eIF-5_eIF-2B PF01873.17 KNZ76772.1 - 1.7e-41 140.8 0.4 2.7e-41 140.1 0.4 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 KNZ76772.1 - 0.003 17.1 0.1 0.006 16.1 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 KNZ76772.1 - 0.016 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 KNZ76772.1 - 0.059 13.2 0.1 17 5.3 0.0 2.6 2 0 0 2 2 2 0 HypF finger Arc_trans_TRASH PF08394.10 KNZ76772.1 - 0.76 10.2 4.3 9.8 6.6 0.0 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain DUF1754 PF08555.10 KNZ76772.1 - 3 8.7 10.9 1.5 9.7 3.9 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PCI PF01399.27 KNZ76773.1 - 8.9e-07 29.4 0.0 2.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 KNZ76773.1 - 0.08 13.0 0.1 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KNZ76774.1 - 8.2e-67 225.3 0.0 9.7e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76774.1 - 1.3e-31 109.8 0.0 4e-31 108.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ76774.1 - 0.00032 20.1 0.3 0.00052 19.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ76774.1 - 0.0019 17.2 0.1 0.0025 16.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KNZ76774.1 - 0.0025 17.2 0.0 0.0048 16.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ76774.1 - 0.0034 17.3 0.6 2.5 8.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ76774.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Torus PF16131.5 KNZ76775.1 - 8.2e-09 36.1 6.2 0.00058 20.5 0.7 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 KNZ76775.1 - 1e-06 28.4 12.4 0.00068 19.4 2.4 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KNZ76775.1 - 4.7e-05 23.3 13.9 0.00039 20.4 2.6 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 KNZ76775.1 - 0.00043 20.1 10.1 0.0018 18.1 2.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 KNZ76775.1 - 0.00099 19.3 1.3 0.0018 18.5 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger containing family NAD_binding_6 PF08030.12 KNZ76776.1 - 2e-24 86.5 0.0 3.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KNZ76776.1 - 3.7e-17 62.6 9.9 3.7e-17 62.6 9.9 2.7 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KNZ76776.1 - 3.1e-15 56.2 0.1 8.8e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 KNZ76776.1 - 0.0042 17.7 0.0 0.033 14.8 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain EthD PF07110.11 KNZ76777.1 - 0.0039 18.3 0.0 4.2 8.6 0.0 2.3 2 0 0 2 2 2 2 EthD domain DUF4487 PF14868.6 KNZ76777.1 - 0.24 10.2 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) WD40 PF00400.32 KNZ76778.1 - 6.9e-28 96.3 17.6 6.8e-08 33.1 2.2 5.3 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ76778.1 - 6.4e-09 36.0 0.4 0.00021 21.5 0.0 3.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ76778.1 - 7.8e-06 25.1 0.2 0.036 13.0 0.0 2.8 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KNZ76778.1 - 0.00012 21.5 0.0 0.076 12.3 0.0 2.9 3 0 0 3 3 3 1 WD40-like domain DUF1513 PF07433.11 KNZ76778.1 - 0.00075 18.7 0.1 0.0058 15.8 0.0 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF1513) Nbas_N PF15492.6 KNZ76778.1 - 0.0083 15.5 0.2 2.1 7.6 0.0 2.8 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 KNZ76778.1 - 0.093 11.3 1.2 2.1 6.9 0.0 2.4 1 1 0 2 2 2 0 Nucleoporin Nup120/160 EIF_2_alpha PF07541.12 KNZ76780.1 - 1.3e-35 122.0 0.0 1.9e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit DUF4923 PF16270.5 KNZ76780.1 - 0.033 14.0 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Peptidase_C13 PF01650.18 KNZ76781.1 - 3.2e-40 138.3 0.1 4.2e-40 137.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family AAA_lid_4 PF17864.1 KNZ76782.1 - 0.18 11.6 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_2 PF00891.18 KNZ76783.1 - 8.9e-30 103.5 0.0 1.7e-28 99.4 0.0 2.1 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 KNZ76783.1 - 0.00033 21.3 0.0 0.00082 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ76783.1 - 0.0099 16.6 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation2 PF16864.5 KNZ76783.1 - 0.023 14.6 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_31 PF13847.6 KNZ76783.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cu-oxidase PF00394.22 KNZ76784.1 - 2.5e-41 141.4 2.5 9.2e-41 139.6 0.3 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ76784.1 - 5.8e-36 123.1 3.0 8.4e-34 116.1 0.2 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ76784.1 - 6.7e-36 123.0 10.1 9.7e-32 109.6 0.1 4.0 3 1 0 3 3 3 3 Multicopper oxidase Ras PF00071.22 KNZ76785.1 - 3.8e-58 195.7 0.2 4.4e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ76785.1 - 2.4e-33 114.9 0.0 4e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ76785.1 - 3.5e-14 52.6 0.0 4.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ76785.1 - 5.3e-07 29.2 0.0 6.7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ76785.1 - 4.2e-06 26.8 0.0 5.4e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNZ76785.1 - 0.00017 21.2 0.1 0.00029 20.4 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KNZ76785.1 - 0.0022 18.4 0.0 0.004 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KNZ76785.1 - 0.0071 15.8 0.0 0.01 15.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 KNZ76785.1 - 0.034 14.1 0.4 0.54 10.1 0.0 2.2 2 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 KNZ76785.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 KNZ76785.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 KNZ76785.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Septin G-alpha PF00503.20 KNZ76785.1 - 0.14 11.2 1.6 3.5 6.7 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit MFS_1 PF07690.16 KNZ76786.1 - 1.6e-07 30.6 22.4 1.5e-05 24.1 8.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 KNZ76787.1 - 8.3e-20 71.2 0.0 8.8e-19 67.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76787.1 - 1.7e-05 24.2 0.8 0.00022 20.6 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ76787.1 - 0.18 10.5 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BTB PF00651.31 KNZ76788.1 - 6.8e-10 39.2 0.1 2.2e-07 31.1 0.2 3.2 3 0 0 3 3 3 2 BTB/POZ domain Pkinase PF00069.25 KNZ76790.1 - 5.1e-19 68.7 0.0 4.9e-18 65.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76790.1 - 0.00051 19.4 0.0 0.025 13.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ76791.1 - 2.6e-22 79.5 0.0 2.1e-14 53.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76791.1 - 0.00028 20.3 0.1 0.2 10.9 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase DEAD PF00270.29 KNZ76792.1 - 1.3e-42 145.5 0.1 2e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ76792.1 - 1.7e-15 57.3 0.0 2.7e-14 53.5 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ76792.1 - 4e-07 30.2 0.0 6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KNZ76792.1 - 0.0023 18.3 0.4 0.0042 17.4 0.3 1.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KNZ76792.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Retrotran_gag_2 PF14223.6 KNZ76793.1 - 2.7e-07 30.3 0.0 3.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KNZ76793.1 - 0.13 12.1 0.0 0.69 9.8 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Cys_Met_Meta_PP PF01053.20 KNZ76794.1 - 4.1e-17 61.8 0.0 5.1e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fe_dep_repr_C PF02742.15 KNZ76794.1 - 0.068 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Asparaginase_C PF17763.1 KNZ76794.1 - 0.16 12.2 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain SRF-TF PF00319.18 KNZ76795.1 - 1.3e-14 53.4 0.0 1.7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Thiolase_N PF00108.23 KNZ76799.1 - 1.5e-74 250.6 1.2 1.5e-74 250.6 1.2 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNZ76799.1 - 8.8e-36 122.3 1.4 2.7e-35 120.7 1.4 1.8 1 1 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KNZ76799.1 - 0.022 14.3 3.9 0.2 11.2 0.4 3.1 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain CE2_N PF17996.1 KNZ76800.1 - 0.002 18.1 0.0 0.008 16.1 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate esterase 2 N-terminal Pro-rich_19 PF15455.6 KNZ76801.1 - 0.048 12.8 2.0 0.064 12.4 2.0 1.1 1 0 0 1 1 1 0 Proline-rich 19 zf-RVT PF13966.6 KNZ76802.1 - 0.042 14.6 0.4 0.055 14.2 0.4 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ76803.1 - 1.4e-20 73.2 0.0 2.9e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ76803.1 - 6.3e-13 48.9 0.0 1.2e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase HSP20 PF00011.21 KNZ76803.1 - 7.7e-05 22.8 0.1 0.00015 21.8 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family RVT_1 PF00078.27 KNZ76803.1 - 0.045 13.3 0.4 0.12 11.8 0.4 1.7 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ArsA_HSP20 PF17886.1 KNZ76803.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 HSP20-like domain found in ArsA PAS_9 PF13426.7 KNZ76804.1 - 3.6e-25 88.2 0.0 1.9e-12 47.3 0.0 3.8 4 0 0 4 4 4 3 PAS domain PAS PF00989.25 KNZ76804.1 - 3e-20 72.3 0.0 2.4e-07 30.7 0.0 4.5 4 1 0 4 4 4 3 PAS fold PAS_3 PF08447.12 KNZ76804.1 - 2.1e-17 63.2 0.0 1.4e-09 38.1 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.6 KNZ76804.1 - 4.9e-09 36.3 0.0 4.2e-05 23.6 0.0 3.2 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.10 KNZ76804.1 - 4.1e-07 30.2 0.1 0.0011 19.2 0.0 3.8 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.7 KNZ76804.1 - 0.026 14.6 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 PAS domain Retrotrans_gag PF03732.17 KNZ76806.1 - 0.0003 21.0 0.6 0.0004 20.6 0.4 1.4 1 1 0 1 1 1 1 Retrotransposon gag protein DUF4632 PF15451.6 KNZ76808.1 - 0.024 14.7 0.2 0.051 13.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF3176 PF11374.8 KNZ76808.1 - 0.043 14.0 0.3 0.09 13.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) AcrZ PF10766.9 KNZ76808.1 - 0.46 10.1 1.7 1.6 8.3 0.5 2.2 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ KH_8 PF17903.1 KNZ76809.1 - 1.1e-32 111.9 0.1 8e-32 109.2 0.0 2.2 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 KNZ76809.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 KNZ76809.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 KH domain NCBP3 PF10309.9 KNZ76810.1 - 9.1e-10 38.2 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 FoP_duplication PF13865.6 KNZ76810.1 - 4.6e-05 23.9 22.1 5.5e-05 23.6 6.4 3.3 3 0 0 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 NmrA PF05368.13 KNZ76811.1 - 6.6e-26 91.3 0.0 8.2e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ76811.1 - 4.6e-07 29.9 0.0 8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF3546 PF12066.8 KNZ76812.1 - 8.1e-15 55.0 2.5 1.7e-14 53.9 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 KNZ76812.1 - 4.2e-13 50.1 0.7 4.2e-13 50.1 0.7 3.0 3 1 1 4 4 4 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 KNZ76812.1 - 0.0021 17.8 1.5 0.0061 16.3 1.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.7 KNZ76812.1 - 0.011 16.0 0.7 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DcpS_C PF11969.8 KNZ76812.1 - 0.016 15.7 0.8 0.031 14.7 0.8 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding zf-C2H2 PF00096.26 KNZ76812.1 - 0.5 10.9 5.1 0.22 12.0 1.4 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF1682 PF07946.14 KNZ76812.1 - 2.1 7.5 13.3 3.5 6.7 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LMBR1 PF04791.16 KNZ76812.1 - 4.8 6.0 3.8 7.2 5.4 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Response_reg PF00072.24 KNZ76813.1 - 5.2e-21 74.9 0.2 2.3e-15 56.7 0.2 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Oxidored_nitro PF00148.19 KNZ76813.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase TOBE_2 PF08402.10 KNZ76813.1 - 0.12 12.6 0.2 0.71 10.1 0.1 2.2 2 0 0 2 2 2 0 TOBE domain DDE_1 PF03184.19 KNZ76814.1 - 4.7e-33 114.3 0.4 6.5e-33 113.8 0.4 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease MIF4G_like_2 PF09090.11 KNZ76815.1 - 2.1e-74 250.4 0.0 3.1e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 KNZ76815.1 - 1.2e-64 217.6 0.0 3e-64 216.3 0.0 1.7 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 KNZ76815.1 - 0.0052 16.5 0.0 0.065 12.9 0.0 2.4 2 0 0 2 2 2 1 MIF4G domain PPR_2 PF13041.6 KNZ76816.1 - 2.2e-08 34.2 0.9 0.00019 21.6 0.0 4.8 5 0 0 5 5 5 2 PPR repeat family PPR_1 PF12854.7 KNZ76816.1 - 0.00055 19.6 0.1 0.14 11.9 0.0 3.8 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 KNZ76816.1 - 0.034 14.2 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain JmjC PF02373.22 KNZ76817.1 - 5.5e-07 30.0 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 KNZ76817.1 - 0.011 15.5 0.0 0.043 13.5 0.0 2.1 1 1 0 1 1 1 0 Cupin-like domain Pkinase PF00069.25 KNZ76817.1 - 0.1 11.9 0.1 3 7.1 0.1 2.3 1 1 1 2 2 2 0 Protein kinase domain RRM_1 PF00076.22 KNZ76818.1 - 0.0059 16.4 0.0 0.36 10.7 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.24 KNZ76819.1 - 4e-48 164.4 15.6 2e-29 102.8 4.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ76819.1 - 4.2e-18 65.4 21.3 4.2e-18 65.4 21.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3493 PF11998.8 KNZ76819.1 - 0.19 11.9 4.2 1.8 8.8 0.2 3.3 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Kdo PF06293.14 KNZ76820.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family LepB_N PF18640.1 KNZ76820.1 - 0.11 12.1 0.4 0.58 9.7 0.1 2.2 3 0 0 3 3 3 0 LepB N-terminal domain AP_endonuc_2 PF01261.24 KNZ76821.1 - 1.1e-19 70.7 0.1 5.5e-19 68.4 0.0 2.0 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF3342 PF11822.8 KNZ76822.1 - 0.0064 16.7 2.4 0.053 13.7 0.2 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3342) IRF PF00605.17 KNZ76822.1 - 0.042 14.1 0.2 0.071 13.4 0.2 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor Baculo_LEF-11 PF06385.12 KNZ76822.1 - 0.051 14.1 1.8 0.11 13.0 0.2 2.0 1 1 1 2 2 2 0 Baculovirus LEF-11 protein AAA_6 PF12774.7 KNZ76824.1 - 0.17 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PIF1 PF05970.14 KNZ76825.1 - 2e-51 175.3 0.1 2.3e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ76825.1 - 0.0006 19.6 0.0 0.00066 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ76825.1 - 0.0013 18.7 0.0 0.008 16.2 0.0 1.8 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ76825.1 - 0.0071 16.7 0.0 0.0082 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ76825.1 - 0.011 15.4 0.1 0.027 14.2 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.8 KNZ76825.1 - 0.077 11.8 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_25 PF13481.6 KNZ76825.1 - 0.077 12.6 0.1 0.07 12.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ76825.1 - 0.08 13.3 0.1 0.39 11.1 0.1 2.0 1 1 0 1 1 1 0 RNA helicase Torsin PF06309.11 KNZ76825.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Torsin PIF1 PF05970.14 KNZ76826.1 - 1.1e-33 116.9 0.3 1.2e-33 116.8 0.3 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ76826.1 - 0.0037 16.9 0.0 0.0083 15.8 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Pox_I6 PF04595.13 KNZ76826.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family DAO PF01266.24 KNZ76828.1 - 6.7e-51 173.9 0.2 8.3e-51 173.6 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KNZ76828.1 - 1.2e-05 24.9 0.2 1.7e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ76828.1 - 1.6e-05 24.2 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ76828.1 - 0.00031 20.1 0.0 0.0007 18.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ76828.1 - 0.0014 18.8 0.6 0.0069 16.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KNZ76828.1 - 0.008 16.7 0.2 0.018 15.6 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ76828.1 - 0.011 14.4 0.3 0.017 13.9 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KNZ76828.1 - 0.011 14.8 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KNZ76828.1 - 0.02 14.8 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KNZ76828.1 - 0.078 12.2 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ76828.1 - 0.098 11.9 0.2 0.23 10.7 0.1 1.6 2 0 0 2 2 2 0 Thi4 family ERG2_Sigma1R PF04622.12 KNZ76829.1 - 4.9e-97 323.3 0.0 5.7e-97 323.1 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein SSXT PF05030.12 KNZ76830.1 - 4.7e-06 26.1 0.0 4.7e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 SSXT protein (N-terminal region) SH3_1 PF00018.28 KNZ76831.1 - 2.8e-14 52.5 0.1 4.4e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ76831.1 - 1.1e-13 50.8 0.1 1.8e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ76831.1 - 5.9e-13 48.3 0.0 9.2e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SPESP1 PF15754.5 KNZ76831.1 - 0.2 10.8 5.9 2.2 7.4 1.2 2.1 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 DASH_Dad4 PF08650.10 KNZ76834.1 - 0.19 11.8 1.8 5.3 7.1 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 KxDL PF10241.9 KNZ76834.1 - 0.36 11.1 4.4 1.3 9.3 0.5 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Ribosomal_L2_C PF03947.18 KNZ76835.1 - 2e-45 154.0 2.7 2e-45 154.0 2.7 1.5 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KNZ76835.1 - 5.4e-16 58.3 0.1 1.3e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain tRNA-synt_2 PF00152.20 KNZ76836.1 - 2.2e-63 214.2 0.0 1.5e-62 211.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNZ76836.1 - 7e-09 35.6 0.3 1.7e-08 34.3 0.2 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KNZ76836.1 - 0.076 12.5 0.3 2.3 7.6 0.1 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) UAA PF08449.11 KNZ76837.1 - 1.3e-61 208.5 9.6 1.6e-37 129.4 0.6 2.4 2 1 0 2 2 2 2 UAA transporter family PUNUT PF16913.5 KNZ76837.1 - 8.4e-05 21.9 3.0 8.4e-05 21.9 3.0 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 KNZ76837.1 - 0.025 14.8 5.3 0.025 14.8 5.3 3.3 3 1 0 3 3 3 0 EamA-like transporter family Sex_peptide PF08138.11 KNZ76837.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.0 4 0 0 4 4 4 0 Sex peptide (SP) family N1221 PF07923.13 KNZ76838.1 - 0.082 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 N1221-like protein DUF1818 PF08848.11 KNZ76838.1 - 0.17 12.0 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) EAF PF09816.9 KNZ76839.1 - 1.7e-18 66.9 0.0 4.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cu-oxidase PF00394.22 KNZ76840.1 - 4e-45 153.8 0.5 2.3e-42 144.8 0.0 3.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ76840.1 - 7.4e-39 132.6 1.4 3.3e-36 124.0 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ76840.1 - 1.7e-30 105.5 1.2 3.7e-29 101.2 0.1 3.0 4 0 0 4 4 4 1 Multicopper oxidase Propep_M14 PF02244.16 KNZ76841.1 - 0.18 12.2 0.0 16 6.0 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase activation peptide Ferritin_2 PF13668.6 KNZ76842.1 - 1.4e-20 73.9 1.4 5e-15 55.9 0.5 2.4 1 1 1 2 2 2 2 Ferritin-like domain PRKCSH-like PF12999.7 KNZ76844.1 - 7.8e-49 165.8 1.0 7.8e-49 165.8 1.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KNZ76844.1 - 3.1e-24 85.4 0.0 6.9e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KNZ76844.1 - 3e-10 41.0 0.8 9.6e-10 39.3 0.8 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HBM PF16591.5 KNZ76844.1 - 0.1 12.0 4.0 0.18 11.2 4.0 1.4 1 0 0 1 1 1 0 Helical bimodular sensor domain Ldl_recept_a PF00057.18 KNZ76844.1 - 0.11 12.8 13.5 0.61 10.3 2.6 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A CaMBD PF02888.16 KNZ76844.1 - 0.12 12.6 1.3 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Calmodulin binding domain 3HCDH_N PF02737.18 KNZ76844.1 - 0.14 12.0 0.5 0.29 11.0 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ERp29 PF07749.12 KNZ76844.1 - 1.2 10.0 7.0 3.9 8.5 5.3 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Phage_GPO PF05929.11 KNZ76844.1 - 2.5 7.7 6.0 4.3 6.9 6.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 KNZ76844.1 - 2.8 7.2 5.2 1 8.6 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 KNZ76844.1 - 5.3 5.8 8.1 8 5.2 8.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC24_OB1 PF17246.2 KNZ76844.1 - 8.3 6.5 6.4 3.3 7.8 3.3 1.8 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 Ribosomal_S25 PF03297.15 KNZ76845.1 - 1.4e-37 128.0 2.9 1.5e-37 127.8 2.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein PIH1 PF08190.12 KNZ76845.1 - 0.02 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 PIH1 N-terminal domain AIPR PF10592.9 KNZ76845.1 - 0.038 13.6 0.1 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 AIPR protein FtsK_gamma PF09397.10 KNZ76845.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Ftsk gamma domain Nop PF01798.18 KNZ76846.1 - 2.3e-85 285.7 0.2 4.1e-85 284.9 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KNZ76846.1 - 1.1e-20 73.8 0.2 3.1e-20 72.3 0.2 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KNZ76846.1 - 6 6.9 27.6 10 6.2 27.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 adh_short PF00106.25 KNZ76847.1 - 2.9e-05 23.6 0.0 0.38 10.2 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase FGGY_C PF02782.16 KNZ76848.1 - 1.4e-46 158.7 0.0 2e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KNZ76848.1 - 7.3e-15 55.2 0.0 1.8e-13 50.6 0.0 2.7 1 1 1 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 KNZ76848.1 - 3.8e-06 26.6 0.6 0.0052 16.3 0.1 3.0 1 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Peptidase_S10 PF00450.22 KNZ76849.1 - 4.5e-100 336.0 0.1 6.4e-100 335.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase p450 PF00067.22 KNZ76850.1 - 9e-58 196.1 0.0 1.7e-57 195.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ferritin_2 PF13668.6 KNZ76851.1 - 6.9e-34 117.0 0.4 1.1e-33 116.3 0.4 1.3 1 0 0 1 1 1 1 Ferritin-like domain Cyclin PF08613.11 KNZ76854.1 - 5.1e-43 147.2 0.0 5.1e-43 147.2 0.0 2.1 3 0 0 3 3 3 1 Cyclin SPX PF03105.19 KNZ76854.1 - 1.3 8.9 20.2 2.1 8.2 12.9 2.3 2 0 0 2 2 2 0 SPX domain SOG2 PF10428.9 KNZ76854.1 - 5 6.2 31.9 1.6 7.8 5.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein zf-RVT PF13966.6 KNZ76856.1 - 0.002 18.8 0.2 0.0034 18.1 0.2 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ76856.1 - 0.0051 16.8 1.6 0.011 15.7 1.6 1.6 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KNZ76856.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Ceramidase_alk PF04734.13 KNZ76857.1 - 2.7e-71 240.8 2.3 7e-67 226.2 0.4 3.9 1 1 1 2 2 2 2 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KNZ76857.1 - 2.4e-36 125.1 0.2 4.2e-36 124.3 0.2 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Abhydrolase_4 PF08386.10 KNZ76858.1 - 3.7e-20 71.9 0.0 6.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KNZ76858.1 - 1.6e-18 67.3 0.1 2.8e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cyclin_N PF00134.23 KNZ76859.1 - 1.7e-09 37.5 0.1 3.9e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KNZ76859.1 - 0.0029 18.0 0.1 0.02 15.3 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Ldh_1_C PF02866.18 KNZ76860.1 - 6.3e-47 159.6 0.0 1.1e-46 158.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KNZ76860.1 - 3.1e-31 108.3 0.2 6.2e-31 107.4 0.2 1.5 1 1 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KNZ76860.1 - 0.012 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KNZ76860.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KNZ76860.1 - 0.026 14.9 0.3 0.091 13.2 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CbiG_N PF11760.8 KNZ76860.1 - 0.06 13.4 2.5 2 8.5 0.1 2.6 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal PMT PF02366.18 KNZ76861.1 - 1.1e-80 270.8 15.6 1.9e-80 270.0 15.6 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KNZ76861.1 - 4e-67 225.7 10.6 4e-67 225.7 10.6 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KNZ76861.1 - 3.5e-40 137.9 1.3 4.1e-40 137.6 0.1 1.7 2 0 0 2 2 2 1 MIR domain DUF1240 PF06836.12 KNZ76861.1 - 0.18 12.3 4.9 14 6.3 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1240) DUF2975 PF11188.8 KNZ76861.1 - 1.6 8.6 10.1 1.3 9.0 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) DUF21 PF01595.20 KNZ76862.1 - 3.2e-18 66.0 1.7 8.1e-18 64.7 0.8 2.1 2 1 0 2 2 2 1 Cyclin M transmembrane N-terminal domain F-box-like PF12937.7 KNZ76865.1 - 6.3 6.8 8.1 0.56 10.1 2.3 2.4 2 0 0 2 2 2 0 F-box-like Abhydrolase_1 PF00561.20 KNZ76866.1 - 9.4e-21 74.6 0.3 3.3e-20 72.8 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ76866.1 - 3.2e-12 47.5 6.8 8.5e-12 46.1 6.8 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ76866.1 - 1.1e-10 41.2 0.0 7e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 KNZ76866.1 - 0.087 11.5 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Ndr family Maf PF02545.14 KNZ76867.1 - 7.7e-43 146.2 0.0 1.1e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein DUF4012 PF13196.6 KNZ76867.1 - 0.011 16.2 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) TPR_6 PF13174.6 KNZ76867.1 - 0.092 13.4 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA PF00004.29 KNZ76869.1 - 2.8e-46 157.2 0.0 3.8e-41 140.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ76869.1 - 1.1e-09 38.0 0.7 2.8e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KNZ76869.1 - 1.2e-06 29.0 0.1 3.9e-05 24.1 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 KNZ76869.1 - 2.7e-06 27.2 0.0 1.9e-05 24.5 0.0 2.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_2 PF07724.14 KNZ76869.1 - 2.5e-05 24.4 0.0 6.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KNZ76869.1 - 0.0029 17.2 0.0 0.42 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KNZ76869.1 - 0.0033 17.4 0.0 0.02 14.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KNZ76869.1 - 0.007 16.2 3.5 0.9 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNZ76869.1 - 0.014 15.6 1.4 0.038 14.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KNZ76869.1 - 0.025 14.8 4.9 0.15 12.4 0.2 3.9 4 1 0 4 4 3 0 AAA domain Sigma54_activat PF00158.26 KNZ76869.1 - 0.053 13.2 0.0 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 KNZ76869.1 - 0.06 13.6 1.2 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KNZ76869.1 - 0.063 13.8 0.0 0.063 13.8 0.0 2.5 3 0 0 3 3 1 0 AAA domain Mg_chelatase PF01078.21 KNZ76869.1 - 0.07 12.5 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KNZ76869.1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KNZ76869.1 - 0.083 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KNZ76869.1 - 0.095 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain PhoH PF02562.16 KNZ76869.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF3394 PF11874.8 KNZ76869.1 - 0.15 11.7 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) RNA_helicase PF00910.22 KNZ76869.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SUIM_assoc PF16619.5 KNZ76869.1 - 8.6 6.5 8.5 2 8.6 0.2 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CRAL_TRIO_2 PF13716.6 KNZ76871.1 - 1.2e-29 103.2 0.2 2.1e-29 102.5 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 KNZ76871.1 - 2e-26 92.6 0.0 3.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.20 KNZ76871.1 - 0.00036 20.3 0.1 0.00074 19.3 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Sigma54_activat PF00158.26 KNZ76871.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Suf PF05843.14 KNZ76872.1 - 1.1e-73 248.9 0.0 3.6e-71 240.6 0.0 3.1 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KNZ76872.1 - 3.3e-12 46.2 5.7 0.00079 20.0 0.0 6.7 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ76872.1 - 1.7e-07 31.6 1.1 0.0041 17.6 0.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat FTCD_C PF04961.12 KNZ76872.1 - 0.0065 16.3 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase NRDE-2 PF08424.10 KNZ76872.1 - 0.012 14.8 5.7 0.081 12.0 1.9 3.9 3 2 0 3 3 3 0 NRDE-2, necessary for RNA interference Integrin_beta PF00362.18 KNZ76872.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Integrin beta chain VWA domain TPR_16 PF13432.6 KNZ76872.1 - 0.74 10.5 7.2 12 6.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S10 PF00450.22 KNZ76874.1 - 8.2e-74 249.5 0.0 1e-73 249.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RRM_1 PF00076.22 KNZ76875.1 - 4.5e-31 106.5 0.2 2.5e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ76875.1 - 2.2e-09 37.3 0.1 0.00036 20.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KNZ76875.1 - 0.0044 17.0 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KNZ76875.1 - 0.22 11.6 0.0 16 5.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif SNO PF01174.19 KNZ76877.1 - 3.7e-49 167.1 0.0 7.3e-39 133.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KNZ76877.1 - 1.4e-08 34.6 0.0 1.9e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 KNZ76877.1 - 2.2e-06 27.4 0.0 3.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 KNZ76877.1 - 0.005 16.6 0.1 0.018 14.8 0.1 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KNZ76877.1 - 0.0056 16.5 0.1 0.0081 16.0 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S10 PF00450.22 KNZ76878.1 - 7e-64 216.8 0.0 2.1e-63 215.2 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase INTS5_C PF14838.6 KNZ76878.1 - 0.15 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus Glyco_hydro_85 PF03644.13 KNZ76879.1 - 7.3e-82 275.2 0.0 1e-81 274.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 An_peroxidase PF03098.15 KNZ76880.1 - 2.7e-38 131.9 0.0 7.7e-28 97.4 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KNZ76880.1 - 2.4e-05 23.3 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L23eN PF03939.13 KNZ76880.1 - 0.45 10.8 1.6 0.98 9.7 1.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain An_peroxidase PF03098.15 KNZ76883.1 - 4.5e-31 108.0 0.0 3.3e-21 75.5 0.0 3.4 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 KNZ76883.1 - 1.4e-05 24.0 0.1 7.2e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Pkinase_Tyr PF07714.17 KNZ76885.1 - 5.9e-32 111.0 0.0 3.3e-31 108.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ76885.1 - 2.5e-29 102.5 0.0 4.8e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TetR_C_30 PF17939.1 KNZ76885.1 - 0.025 14.8 0.0 1.8 8.8 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Kinase-like PF14531.6 KNZ76885.1 - 0.031 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF4543 PF15076.6 KNZ76885.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4543) Kdo PF06293.14 KNZ76885.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KNZ76886.1 - 4.4e-10 39.3 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ76886.1 - 3.9e-09 36.3 0.0 5.5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 KNZ76888.1 - 2.3e-16 60.0 0.0 2.7e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76888.1 - 4.7e-14 52.3 0.0 5.4e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ76888.1 - 0.0025 17.2 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KNZ76888.1 - 0.018 14.6 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KNZ76888.1 - 0.028 13.8 0.1 0.075 12.4 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_Helicase PF02689.14 KNZ76889.1 - 0.00012 20.3 0.1 0.00012 20.2 0.1 1.0 1 0 0 1 1 1 1 Helicase Pkinase_Tyr PF07714.17 KNZ76890.1 - 1.4e-36 126.1 0.0 2.1e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ76890.1 - 2.9e-32 112.1 0.0 5e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ76890.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ76890.1 - 0.0044 16.7 0.0 0.029 14.0 0.0 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 KNZ76890.1 - 0.027 14.4 0.5 0.083 12.8 0.5 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family MerB PF03243.15 KNZ76890.1 - 0.043 14.0 0.0 2.3 8.4 0.0 2.2 2 0 0 2 2 2 0 Alkylmercury lyase Pkinase PF00069.25 KNZ76891.1 - 5.2e-31 108.0 0.0 6.7e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76891.1 - 7.3e-29 100.8 0.0 1.1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ76891.1 - 0.0045 16.4 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNZ76892.1 - 1.6e-33 116.2 0.0 3.3e-33 115.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76892.1 - 1.2e-32 113.3 0.0 2.4e-32 112.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KNZ76892.1 - 0.0024 17.5 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KNZ76892.1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pertus-S4-tox PF09275.10 KNZ76893.1 - 0.068 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Pertussis toxin S4 subunit TFIIA PF03153.13 KNZ76894.1 - 0.0014 18.7 1.3 0.0022 18.0 1.3 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit p31comet PF06581.12 KNZ76894.1 - 0.013 14.7 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Atrophin-1 PF03154.15 KNZ76894.1 - 0.033 12.5 2.2 0.055 11.8 2.2 1.3 1 0 0 1 1 1 0 Atrophin-1 family CDC45 PF02724.14 KNZ76894.1 - 0.2 9.9 7.6 0.27 9.5 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KNZ76894.1 - 0.36 9.0 13.7 0.61 8.2 13.7 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KNZ76894.1 - 0.47 9.8 13.8 0.69 9.3 13.8 1.2 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 KNZ76894.1 - 0.96 9.0 11.6 1.7 8.1 11.6 1.4 1 1 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 KNZ76894.1 - 1 8.6 16.1 1.6 8.0 16.1 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_r3 PF04539.16 KNZ76895.1 - 8e-06 25.9 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Sigma-70 region 3 S-layer PF07752.11 KNZ76895.1 - 0.2 10.7 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 S-layer protein adh_short PF00106.25 KNZ76896.1 - 1.8e-36 125.4 0.0 2.4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ76896.1 - 6.3e-25 88.1 0.0 8.3e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ76896.1 - 9.3e-07 28.9 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KNZ76896.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KNZ76896.1 - 4.9e-05 22.9 0.0 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KNZ76896.1 - 0.0019 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 KNZ76896.1 - 0.032 13.8 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family SBP PF03110.14 KNZ76900.1 - 0.092 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 SBP domain Chromo PF00385.24 KNZ76902.1 - 3.3e-16 58.9 0.1 4e-16 58.7 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ76902.1 - 0.077 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 FMO-like PF00743.19 KNZ76903.1 - 1.6e-15 56.5 0.0 3.4e-13 48.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KNZ76903.1 - 3.4e-15 56.1 0.0 1.8e-14 53.7 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ76903.1 - 3e-12 46.3 0.0 1.1e-08 34.7 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KNZ76903.1 - 3e-12 46.4 0.0 3.4e-10 39.6 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ76903.1 - 4.9e-07 30.2 0.0 0.0036 17.8 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ76903.1 - 4.2e-05 23.7 0.0 0.15 12.3 0.0 3.3 4 0 0 4 4 3 2 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KNZ76903.1 - 0.0012 18.9 0.0 0.13 12.3 0.0 2.5 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KNZ76903.1 - 0.0012 18.1 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KNZ76903.1 - 0.003 16.9 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain 2-Hacid_dh_C PF02826.19 KNZ76903.1 - 0.023 14.1 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KNZ76903.1 - 0.034 13.2 0.0 0.49 9.4 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KNZ76903.1 - 0.1 12.6 0.2 16 5.4 0.0 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 KNZ76903.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KNZ76903.1 - 0.11 11.5 0.0 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 KNZ76903.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Asp_protease_2 PF13650.6 KNZ76904.1 - 0.0022 18.6 0.0 0.011 16.3 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ76904.1 - 0.0043 17.6 0.2 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease AMP-binding PF00501.28 KNZ76905.1 - 1e-10 40.8 0.0 1.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NMD3 PF04981.13 KNZ76906.1 - 1.9e-27 96.3 5.7 6.1e-18 65.2 1.2 2.3 1 1 1 2 2 2 2 NMD3 family DUF35_N PF12172.8 KNZ76906.1 - 0.088 12.7 7.3 0.89 9.5 1.0 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TPR_14 PF13428.6 KNZ76907.1 - 0.013 16.2 0.0 2.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ76907.1 - 0.065 13.8 0.0 7.5 7.1 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Nramp PF01566.18 KNZ76908.1 - 7.3e-92 308.1 18.8 1.1e-91 307.5 18.8 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Pannexin_like PF12534.8 KNZ76908.1 - 0.0055 15.8 0.2 0.096 11.8 0.0 2.1 2 0 0 2 2 2 1 Pannexin-like TM region of LRRC8 DUF4501 PF14946.6 KNZ76908.1 - 0.97 9.5 3.5 6.6 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) Sugar_tr PF00083.24 KNZ76910.1 - 5.4e-28 98.1 28.3 1e-17 64.2 9.7 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ76910.1 - 1.4e-14 53.8 49.8 1.2e-10 40.9 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2235 PF09994.9 KNZ76912.1 - 4.2e-96 321.7 0.0 5.2e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KNZ76912.1 - 0.094 12.6 0.0 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GST_C_2 PF13410.6 KNZ76914.1 - 0.0073 16.3 0.1 0.061 13.4 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ECH_2 PF16113.5 KNZ76916.1 - 0.074 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase RVP_2 PF08284.11 KNZ76917.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KNZ76917.1 - 0.16 12.6 0.0 0.25 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Acetone_carb_G PF08882.11 KNZ76922.1 - 0.011 15.9 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit CxC1 PF18802.1 KNZ76923.1 - 0.00018 21.6 0.4 0.00036 20.7 0.4 1.4 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases LicD PF04991.13 KNZ76924.1 - 0.17 12.0 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 LicD family Ubiq_cyt_C_chap PF03981.12 KNZ76925.1 - 1.1e-26 93.6 0.0 1.8e-13 50.8 0.0 3.1 2 1 0 2 2 2 2 Ubiquinol-cytochrome C chaperone CENP-B_dimeris PF09026.10 KNZ76926.1 - 1.6 9.2 9.5 2.9 8.3 9.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KNZ76926.1 - 4.4 6.5 5.7 6.6 6.0 5.7 1.3 1 0 0 1 1 1 0 NOA36 protein Aminotran_1_2 PF00155.21 KNZ76928.1 - 4.3e-51 174.2 0.0 4.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4614 PF15391.6 KNZ76928.1 - 0.22 11.5 0.7 0.42 10.6 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) zf-RVT PF13966.6 KNZ76929.1 - 1.7e-05 25.4 0.1 2.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ76929.1 - 0.00083 19.3 1.9 0.0028 17.6 1.9 1.9 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 KNZ76929.1 - 0.11 12.6 0.2 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 Zinc ribbon domain WD40 PF00400.32 KNZ76930.1 - 1.4e-45 152.4 28.7 2.6e-12 47.0 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ76930.1 - 3.4e-16 59.3 0.8 0.00071 19.8 0.0 5.3 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ76930.1 - 1.3e-06 27.7 0.4 0.0067 15.4 0.0 4.1 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KNZ76930.1 - 0.0061 16.5 1.0 0.99 9.4 0.1 3.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat SHMT PF00464.19 KNZ76931.1 - 7.8e-166 551.6 0.0 9.1e-166 551.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase HIG_1_N PF04588.13 KNZ76932.1 - 2.1e-18 66.3 0.6 3.2e-18 65.7 0.6 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF883 PF05957.13 KNZ76932.1 - 0.35 11.5 3.4 1 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Mis12 PF05859.12 KNZ76933.1 - 4.3e-40 136.9 0.3 7.6e-40 136.1 0.3 1.4 1 0 0 1 1 1 1 Mis12 protein SPX PF03105.19 KNZ76933.1 - 0.063 13.2 0.2 0.083 12.8 0.2 1.2 1 0 0 1 1 1 0 SPX domain Alba PF01918.21 KNZ76934.1 - 0.0089 15.8 0.1 0.051 13.4 0.1 2.2 1 1 0 1 1 1 1 Alba Cullin PF00888.22 KNZ76935.1 - 3.8e-16 58.9 0.0 8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KNZ76935.1 - 7e-16 58.5 0.0 3.4e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 AdoHcyase PF05221.17 KNZ76936.1 - 3.8e-131 436.7 0.0 1.4e-73 247.7 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KNZ76936.1 - 4.8e-85 283.6 0.2 7.6e-85 282.9 0.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KNZ76936.1 - 1.3e-08 34.4 0.0 2.6e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KNZ76936.1 - 5e-05 22.9 0.1 8.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 KNZ76936.1 - 0.0022 18.2 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 KNZ76936.1 - 0.1 13.2 0.1 0.23 12.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 KNZ76936.1 - 0.12 12.8 0.1 0.35 11.3 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Mitochondr_Som1 PF11093.8 KNZ76937.1 - 2e-05 24.5 0.1 3.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Tht1 PF04163.12 KNZ76939.1 - 3.5e-09 36.0 16.0 1.8e-08 33.6 16.0 1.9 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein IFT57 PF10498.9 KNZ76939.1 - 0.12 11.3 8.0 0.017 14.1 3.3 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 zf-C4H2 PF10146.9 KNZ76939.1 - 0.39 11.0 4.6 0.87 9.9 4.6 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein YbaJ PF10757.9 KNZ76939.1 - 1.1 9.9 5.6 0.26 11.9 0.3 2.6 4 0 0 4 4 4 0 Biofilm formation regulator YbaJ TRPM_tetra PF16519.5 KNZ76939.1 - 4.9 7.3 8.1 2.7 8.2 0.1 3.6 3 0 0 3 3 3 0 Tetramerisation domain of TRPM Abhydrolase_1 PF00561.20 KNZ76940.1 - 8.1e-42 143.6 0.0 1e-41 143.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ76940.1 - 0.0024 18.5 7.2 0.0054 17.4 7.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Proho_convert PF12177.8 KNZ76940.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Prohormone convertase enzyme RRM_1 PF00076.22 KNZ76941.1 - 5.2e-08 32.6 0.0 4.9e-06 26.3 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_UBOX PF13445.6 KNZ76941.1 - 2.5e-07 30.6 5.8 6.4e-07 29.3 5.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Torus PF16131.5 KNZ76941.1 - 4.3e-07 30.6 1.6 1.4 9.7 0.0 4.4 4 0 0 4 4 4 2 Torus domain zf-C3HC4_2 PF13923.6 KNZ76941.1 - 1.1e-06 28.3 4.3 3.4e-06 26.8 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_3 PF15663.5 KNZ76941.1 - 2.6e-06 27.6 3.0 0.088 13.0 0.1 4.4 5 0 0 5 5 4 2 Zinc-finger containing family zf-C3HC4 PF00097.25 KNZ76941.1 - 8.4e-06 25.6 6.8 2e-05 24.4 6.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNZ76941.1 - 2.5e-05 24.3 7.2 6.5e-05 23.0 7.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KNZ76941.1 - 5.8e-05 22.9 3.8 0.00017 21.4 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 KNZ76941.1 - 0.00022 21.4 1.5 0.13 12.5 0.0 2.7 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KNZ76941.1 - 0.0022 18.3 6.6 0.0022 18.3 6.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KNZ76941.1 - 0.0051 16.7 6.3 0.013 15.5 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 KNZ76941.1 - 0.049 13.7 23.4 0.56 10.3 2.3 4.5 3 1 0 3 3 3 0 Zinc finger domain Prok-RING_4 PF14447.6 KNZ76941.1 - 0.61 10.0 3.6 1.4 8.8 3.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TPMT PF05724.11 KNZ76943.1 - 2.5e-35 122.1 0.0 3.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KNZ76943.1 - 3.6e-12 46.3 0.0 4.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ76943.1 - 1.3e-11 45.0 0.0 1.8e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ76943.1 - 1.8e-08 35.0 0.0 2.6e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ76943.1 - 1.8e-07 31.7 0.0 2.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ76943.1 - 0.0038 16.8 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KNZ76943.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KNZ76943.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 KNZ76943.1 - 0.042 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 KNZ76943.1 - 0.087 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) N2227 PF07942.12 KNZ76943.1 - 0.25 10.5 0.0 12 4.9 0.0 2.1 2 0 0 2 2 2 0 N2227-like protein Pribosyltran PF00156.27 KNZ76945.1 - 1.7e-14 53.6 0.3 2.5e-14 53.1 0.3 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KNZ76945.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase La PF05383.17 KNZ76946.1 - 8.2e-18 64.2 0.0 1.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 La domain Pmp3 PF01679.17 KNZ76947.1 - 4.2e-20 71.7 7.9 5.2e-20 71.4 7.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Rsa3 PF14615.6 KNZ76948.1 - 2.1e-06 27.2 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF1088 PF06469.11 KNZ76948.1 - 0.1 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) DUF4701 PF15773.5 KNZ76948.1 - 1.1 8.2 6.2 1.3 8.0 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) Peroxin-13_N PF04088.13 KNZ76950.1 - 2.2e-45 154.5 0.2 2.8e-45 154.1 0.2 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 KNZ76950.1 - 6.7e-10 38.5 0.0 1.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ76950.1 - 1.4e-09 37.4 1.9 0.0021 17.6 2.6 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KNZ76950.1 - 5.4e-08 32.6 0.1 1.1e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Keratin_2_head PF16208.5 KNZ76950.1 - 2.9 8.0 28.3 4.9 7.3 28.3 1.3 1 0 0 1 1 1 0 Keratin type II head Kelch_6 PF13964.6 KNZ76953.1 - 0.038 14.3 0.1 1.2 9.5 0.1 2.8 2 0 0 2 2 2 0 Kelch motif FA_desaturase PF00487.24 KNZ76954.1 - 6.5e-26 91.7 18.6 1.1e-25 90.9 18.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KNZ76954.1 - 3.1e-06 27.4 0.0 5.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) DUF3433 PF11915.8 KNZ76955.1 - 1.7e-20 73.3 3.2 6e-20 71.5 3.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) MutS_V PF00488.21 KNZ76956.1 - 5e-72 241.9 0.1 8.5e-72 241.1 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KNZ76956.1 - 2.4e-25 89.9 1.0 2.1e-24 86.8 0.2 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 KNZ76956.1 - 7.4e-19 67.9 1.3 7.4e-19 67.9 1.3 2.4 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.17 KNZ76956.1 - 2.6e-14 53.7 0.2 2.4e-13 50.5 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 KNZ76956.1 - 8.3e-07 29.2 0.0 2.2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 KNZ76956.1 - 0.0038 16.8 0.0 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Methyltr_RsmB-F PF01189.17 KNZ76958.1 - 3e-37 128.2 0.0 4.7e-34 117.8 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KNZ76958.1 - 0.0043 17.2 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF2431 PF10354.9 KNZ76958.1 - 0.019 15.3 0.0 0.032 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Sacchrp_dh_C PF16653.5 KNZ76959.1 - 4.7e-89 299.0 0.0 8.7e-89 298.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 KNZ76959.1 - 2.2e-67 226.2 0.0 5.9e-67 224.7 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KNZ76959.1 - 5.5e-24 83.8 1.4 6.6e-24 83.6 0.1 1.8 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Sacchrp_dh_NADP PF03435.18 KNZ76959.1 - 1.3e-23 83.7 2.5 2e-23 83.1 0.2 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KNZ76959.1 - 1.3e-07 31.7 0.0 1.4e-06 28.4 0.0 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 KNZ76959.1 - 3.9e-05 23.6 0.4 7.9e-05 22.6 0.4 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Methyltransf_25 PF13649.6 KNZ76959.1 - 0.00064 20.4 0.0 0.016 15.9 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain SNF2_N PF00176.23 KNZ76960.1 - 2.9e-58 197.3 0.4 6.3e-58 196.1 0.4 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ76960.1 - 2.5e-09 37.4 0.1 9.3e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 KNZ76960.1 - 2.8e-09 36.7 3.1 2.8e-09 36.7 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ76960.1 - 7.5e-09 35.3 5.2 1.7e-08 34.2 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ76960.1 - 1.4e-08 34.4 4.3 3.5e-08 33.2 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ76960.1 - 2.6e-08 33.8 7.4 6.6e-08 32.5 7.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KNZ76960.1 - 2.3e-07 31.0 5.6 6.2e-07 29.7 5.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KNZ76960.1 - 9.7e-07 28.7 3.7 2.2e-06 27.5 3.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 KNZ76960.1 - 9.8e-06 25.7 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 KNZ76960.1 - 0.00017 21.7 6.7 0.00044 20.3 6.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KNZ76960.1 - 0.0025 17.6 7.9 0.021 14.7 7.9 2.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KNZ76960.1 - 0.014 15.7 1.2 0.039 14.2 1.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 KNZ76960.1 - 0.051 13.4 1.4 0.19 11.6 1.4 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 KNZ76960.1 - 0.11 12.2 6.1 0.34 10.7 6.1 1.9 1 0 0 1 1 1 0 RING-like zinc finger Perilipin PF03036.16 KNZ76960.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Perilipin family NOA36 PF06524.12 KNZ76960.1 - 0.28 10.5 6.2 0.59 9.4 6.2 1.5 1 0 0 1 1 1 0 NOA36 protein zf-Nse PF11789.8 KNZ76960.1 - 0.47 10.3 4.4 1.1 9.1 4.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 KNZ76960.1 - 0.97 9.3 4.8 2.6 7.9 4.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain adh_short PF00106.25 KNZ76961.1 - 5.9e-22 78.1 0.0 2.1e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ76961.1 - 2.8e-09 36.9 0.0 1.4e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ76961.1 - 8.6e-06 25.8 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 KR domain IclR PF01614.18 KNZ76961.1 - 0.055 13.3 0.0 6.6 6.6 0.0 2.9 3 0 0 3 3 3 0 Bacterial transcriptional regulator ADH_zinc_N PF00107.26 KNZ76961.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Leuk-A4-hydro_C PF09127.11 KNZ76962.1 - 0.079 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Retrotran_gag_2 PF14223.6 KNZ76963.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF2034 PF10356.9 KNZ76964.1 - 1.1e-22 80.4 0.4 1.5e-18 66.9 0.4 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KNZ76964.1 - 5.6e-07 29.6 0.0 4.6e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Restriction endonuclease G-alpha PF00503.20 KNZ76965.1 - 8.6e-91 304.7 0.3 1.1e-90 304.3 0.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ76965.1 - 1.8e-11 43.8 1.2 5.8e-11 42.2 0.1 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family PRANC PF09372.10 KNZ76966.1 - 0.00068 19.9 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 1 PRANC domain Peroxidase_2 PF01328.17 KNZ76967.1 - 2.1e-42 145.8 0.0 8.8e-42 143.8 0.0 1.8 1 1 0 1 1 1 1 Peroxidase, family 2 RdRP PF05183.12 KNZ76968.1 - 9.7e-75 252.3 0.0 7.4e-56 190.0 0.0 2.1 2 0 0 2 2 2 2 RNA dependent RNA polymerase zf-C3HC4_3 PF13920.6 KNZ76969.1 - 1.1e-06 28.4 4.0 1.7e-06 27.7 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ76969.1 - 6.4e-06 26.0 2.8 1.1e-05 25.3 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KNZ76969.1 - 0.00028 20.7 4.7 0.00056 19.7 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ76969.1 - 0.0011 19.2 4.4 0.0025 18.1 4.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KNZ76969.1 - 0.0015 18.5 3.3 0.0036 17.3 3.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KNZ76969.1 - 0.0048 16.7 5.1 0.0098 15.7 5.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KNZ76969.1 - 0.055 13.3 5.0 0.12 12.2 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KNZ76969.1 - 0.18 11.6 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.6 KNZ76969.1 - 1.4 8.8 3.0 2.7 7.9 3.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KNZ76969.1 - 2.9 8.1 5.4 6.9 6.9 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 KNZ76970.1 - 9e-20 71.1 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ76970.1 - 1.1e-18 67.4 0.0 1.5e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ76970.1 - 0.0034 17.3 0.9 0.0077 16.2 0.9 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ76970.1 - 0.032 13.6 0.3 0.053 12.9 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ76970.1 - 0.039 13.3 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like WaaY PF06176.11 KNZ76970.1 - 0.043 13.4 0.1 0.085 12.5 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF262 PF03235.14 KNZ76970.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 RIO1 PF01163.22 KNZ76970.1 - 0.14 11.8 0.1 0.3 10.7 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Ntox24 PF15529.6 KNZ76971.1 - 1e-13 51.4 15.9 7.8e-07 29.3 4.6 2.4 2 0 0 2 2 2 2 Bacterial toxin 24 CsbD PF05532.12 KNZ76971.1 - 0.89 9.5 4.1 5 7.1 0.5 2.4 2 0 0 2 2 2 0 CsbD-like BTB PF00651.31 KNZ76972.1 - 4.3e-08 33.4 0.2 8.5e-08 32.4 0.2 1.4 1 0 0 1 1 1 1 BTB/POZ domain Actino_peptide PF14408.6 KNZ76973.1 - 0.77 9.9 0.0 0.77 9.9 0.0 4.1 5 0 0 5 5 5 0 Ribosomally synthesised peptide in actinomycetes OmpH PF03938.14 KNZ76975.1 - 0.0097 16.2 23.5 0.041 14.2 8.1 2.7 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) T3SSipB PF16535.5 KNZ76975.1 - 0.013 16.0 3.9 0.013 16.0 3.9 3.2 3 1 0 3 3 3 0 Type III cell invasion protein SipB CSN5_C PF18323.1 KNZ76975.1 - 0.017 16.0 7.1 0.017 16.0 7.1 4.1 3 1 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain GBP_C PF02841.14 KNZ76975.1 - 0.072 12.5 24.8 0.4 10.1 11.9 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain ATG16 PF08614.11 KNZ76975.1 - 0.1 12.8 33.9 0.096 12.9 9.6 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 KNZ76975.1 - 0.18 10.4 34.1 0.63 8.5 34.1 1.9 1 1 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 KNZ76975.1 - 0.51 9.6 21.9 0.09 12.1 3.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 KNZ76975.1 - 2.2 8.3 6.0 1.8 8.6 1.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fib_alpha PF08702.10 KNZ76975.1 - 2.4 8.3 11.5 5.6 7.1 0.9 3.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family KGK PF08872.10 KNZ76975.1 - 7 7.2 9.1 18 5.8 0.6 2.9 2 1 1 3 3 3 0 KGK domain bZIP_1 PF00170.21 KNZ76977.1 - 1.1e-06 28.6 6.3 1.1e-06 28.6 6.3 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KNZ76977.1 - 0.0014 18.7 3.8 0.0014 18.7 3.8 4.7 4 1 1 5 5 5 2 Basic region leucine zipper SlyX PF04102.12 KNZ76977.1 - 0.85 10.3 11.4 0.95 10.1 0.1 3.7 3 0 0 3 3 3 0 SlyX YabA PF06156.13 KNZ76977.1 - 1.1 9.9 0.0 1.1 9.9 0.0 3.2 4 0 0 4 4 4 0 Initiation control protein YabA RT_RNaseH PF17917.1 KNZ76979.1 - 0.025 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KNZ76980.1 - 1.1e-10 41.5 1.4 1.9e-10 40.7 1.4 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Chromo PF00385.24 KNZ76983.1 - 8.8e-15 54.4 0.1 1.1e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ76983.1 - 0.052 13.7 0.1 0.072 13.3 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Homeodomain PF00046.29 KNZ76984.1 - 1.3e-15 57.0 0.4 4.5e-15 55.2 0.4 2.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KNZ76984.1 - 4.8e-08 32.8 0.3 1.2e-07 31.5 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF533 PF04391.12 KNZ76984.1 - 0.073 12.6 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Poxvirus_B22R_C PF13168.6 KNZ76984.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Mating_C PF12737.7 KNZ76985.1 - 8.9e-24 84.5 6.7 8.9e-24 84.5 6.7 1.6 2 0 0 2 2 2 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.11 KNZ76985.1 - 8.8e-13 47.9 0.0 3.2e-12 46.1 0.0 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KNZ76985.1 - 0.015 15.2 0.0 0.084 12.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain Peptidase_M3 PF01432.20 KNZ76986.1 - 7.6e-135 450.7 0.0 9e-135 450.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 KNZ76986.1 - 0.035 14.4 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Effector protein Peptidase_M50B PF13398.6 KNZ76986.1 - 0.055 13.1 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Peptidase M50B-like WSD PF15613.6 KNZ76987.1 - 0.13 12.7 2.6 0.84 10.1 2.6 2.4 1 1 0 1 1 1 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KNZ76987.1 - 0.25 11.7 0.7 0.59 10.5 0.7 1.6 1 1 0 1 1 1 0 DDT domain DUF1754 PF08555.10 KNZ76988.1 - 1.8e-13 51.1 11.3 2.9e-13 50.4 11.3 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SR-25 PF10500.9 KNZ76988.1 - 0.0016 18.1 10.6 0.0022 17.6 10.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein IFRD PF05004.13 KNZ76988.1 - 0.013 14.6 1.9 0.017 14.2 1.9 1.3 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Serglycin PF04360.12 KNZ76988.1 - 0.017 15.0 0.2 0.025 14.5 0.2 1.3 1 0 0 1 1 1 0 Serglycin DUF4684 PF15736.5 KNZ76988.1 - 0.064 11.9 0.4 0.076 11.7 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) NinG PF05766.12 KNZ76988.1 - 0.4 10.6 5.6 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein CDC45 PF02724.14 KNZ76988.1 - 0.63 8.3 5.0 0.75 8.0 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 KNZ76988.1 - 1.2 7.5 4.8 1.4 7.2 4.8 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 KNZ76988.1 - 2 7.1 3.5 2.5 6.8 3.5 1.1 1 0 0 1 1 1 0 Presenilin DUF1751 PF08551.10 KNZ76989.1 - 1.2e-23 83.5 6.0 2.3e-23 82.6 6.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 KNZ76989.1 - 4.1e-05 23.6 10.6 0.00011 22.2 10.6 1.7 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 KNZ76989.1 - 0.00029 20.8 12.0 0.00053 20.0 12.0 1.4 1 0 0 1 1 1 1 Der1-like family Vps51 PF08700.11 KNZ76990.1 - 6.8e-11 42.1 0.8 3.1e-10 40.0 0.8 2.2 1 0 0 1 1 1 1 Vps51/Vps67 SecE PF00584.20 KNZ76991.1 - 7.6e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex PPR_2 PF13041.6 KNZ76992.1 - 1.7e-13 50.5 1.1 0.017 15.3 0.0 8.2 8 3 1 9 9 9 4 PPR repeat family PPR_3 PF13812.6 KNZ76992.1 - 1.1e-07 31.8 0.1 9.2 6.4 0.0 6.4 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.20 KNZ76992.1 - 1.4e-05 25.0 6.4 0.32 11.3 0.0 6.1 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 KNZ76992.1 - 2.1e-05 24.1 5.2 6 6.7 0.0 7.2 9 1 0 9 9 9 3 PPR repeat CobN-Mg_chel PF02514.16 KNZ76992.1 - 0.027 12.2 0.0 0.038 11.7 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase RPM2 PF08579.11 KNZ76992.1 - 0.039 14.3 0.1 18 5.8 0.0 3.6 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) BTAD PF03704.17 KNZ76992.1 - 0.44 11.0 1.5 38 4.7 0.0 3.7 5 0 0 5 5 5 0 Bacterial transcriptional activator domain GDC-P PF02347.16 KNZ76993.1 - 8.5e-176 585.0 0.0 3.3e-165 550.1 0.0 3.1 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 KNZ76993.1 - 0.00027 20.0 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNZ76993.1 - 0.0031 16.8 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF1741 PF08427.10 KNZ76994.1 - 1e-16 61.4 0.5 3.2e-16 59.7 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Lysine_decarbox PF03641.14 KNZ76994.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Possible lysine decarboxylase Nop52 PF05997.12 KNZ76995.1 - 5.1e-74 248.7 0.0 6.7e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.6 KNZ76995.1 - 0.0024 17.5 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Transthyretin PF00576.21 KNZ76996.1 - 8.9e-37 126.1 0.0 1e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family UQ_con PF00179.26 KNZ76997.1 - 2.2e-40 137.5 0.0 2.7e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KNZ76997.1 - 0.033 14.0 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain 2OG-FeII_Oxy PF03171.20 KNZ76998.1 - 0.00022 21.7 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KNZ76998.1 - 0.00076 20.2 0.0 0.0015 19.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal NAAA-beta PF15508.6 KNZ76998.1 - 0.01 16.1 0.0 0.038 14.3 0.0 1.9 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SWC7 PF17330.2 KNZ76998.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Chorismate_bind PF00425.18 KNZ76999.1 - 1.2e-63 215.1 0.0 1.7e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 KNZ76999.1 - 1.5e-30 106.4 0.0 2.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KNZ76999.1 - 4.1e-14 53.0 0.0 1.5e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KNZ76999.1 - 0.00027 20.7 1.0 0.0017 18.2 1.0 2.0 1 1 0 1 1 1 1 Peptidase C26 RTP1_C1 PF10363.9 KNZ77000.1 - 0.051 13.8 0.7 0.38 11.0 0.0 2.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 KNZ77000.1 - 0.12 12.7 0.5 2.2 8.8 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat dCMP_cyt_deam_1 PF00383.23 KNZ77001.1 - 6e-25 87.1 1.2 8.5e-25 86.6 1.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KNZ77001.1 - 2.9e-10 40.0 0.1 5.8e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 KNZ77001.1 - 0.17 12.0 0.3 0.34 11.0 0.3 1.5 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 F-box-like PF12937.7 KNZ77002.1 - 8.9e-06 25.5 4.8 3.2e-05 23.7 4.8 2.1 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 KNZ77003.1 - 2.3e-16 59.9 15.7 0.0021 18.8 0.0 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ77003.1 - 0.0012 19.1 0.1 1.4 9.3 0.0 4.5 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 KNZ77003.1 - 0.046 14.0 0.6 0.55 10.6 0.1 3.0 3 0 0 3 3 3 0 Kelch motif Methyltransf_25 PF13649.6 KNZ77004.1 - 9.4e-12 45.5 0.0 2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ77004.1 - 2.6e-10 40.8 0.0 4.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ77004.1 - 9.9e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ77004.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 KNZ77004.1 - 4.2e-06 26.2 0.0 7.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KNZ77004.1 - 8.6e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ77004.1 - 0.0011 19.6 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KNZ77004.1 - 0.0017 17.9 0.0 0.083 12.4 0.0 2.5 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_29 PF03141.16 KNZ77004.1 - 0.0034 16.0 0.0 0.0063 15.1 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase KAR9 PF08580.10 KNZ77004.1 - 5.4 5.4 6.5 8.3 4.8 6.5 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 MMR_HSR1 PF01926.23 KNZ77005.1 - 1.9e-10 40.8 0.0 5.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ77005.1 - 2e-05 24.2 0.0 7.3e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KNZ77005.1 - 0.00078 19.4 0.0 0.033 14.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KNZ77005.1 - 0.003 17.6 1.8 0.027 14.5 0.8 2.4 2 0 0 2 2 2 1 Dynamin family Roc PF08477.13 KNZ77005.1 - 0.12 12.6 0.1 2.6 8.3 0.1 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KNZ77007.1 - 8.2e-12 45.4 0.0 1.6e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KNZ77007.1 - 5.9e-07 30.0 0.0 3e-06 27.7 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KNZ77007.1 - 6.3e-07 28.8 0.1 2.8e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain APS_kinase PF01583.20 KNZ77007.1 - 0.00055 19.9 0.0 0.002 18.1 0.0 1.9 3 0 0 3 3 2 1 Adenylylsulphate kinase AAA_23 PF13476.6 KNZ77007.1 - 0.0017 18.9 2.5 0.68 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoU_div PF01865.16 KNZ77007.1 - 0.0044 16.4 0.3 0.023 14.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function DUF47 AAA_22 PF13401.6 KNZ77007.1 - 0.012 15.9 0.1 0.1 12.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KNZ77007.1 - 0.019 15.3 0.0 0.061 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KNZ77007.1 - 0.027 14.2 0.0 0.09 12.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KNZ77007.1 - 0.027 14.9 0.4 0.21 12.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KNZ77007.1 - 0.047 14.2 1.4 0.26 11.8 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 KNZ77007.1 - 0.05 14.2 0.7 0.42 11.2 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KNZ77007.1 - 0.052 13.1 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KNZ77007.1 - 0.06 12.6 0.0 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 KNZ77007.1 - 0.065 13.0 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KNZ77007.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 KNZ77007.1 - 0.076 12.1 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3437 PF11919.8 KNZ77007.1 - 0.085 12.8 0.1 11 6.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) AAA_19 PF13245.6 KNZ77007.1 - 0.089 13.1 0.0 0.36 11.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 KNZ77007.1 - 0.12 12.5 0.1 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain HsdM_N PF12161.8 KNZ77007.1 - 0.22 12.1 3.5 0.87 10.2 3.5 2.1 1 1 0 1 1 1 0 HsdM N-terminal domain Phosducin PF02114.16 KNZ77007.1 - 0.57 9.1 4.3 0.11 11.4 0.5 1.7 2 0 0 2 2 2 0 Phosducin Baculo_PEP_C PF04513.12 KNZ77007.1 - 1.5 8.9 6.6 9.8 6.2 0.6 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CoaE PF01121.20 KNZ77007.1 - 3.3 7.3 5.1 14 5.3 0.0 3.1 3 0 0 3 3 3 0 Dephospho-CoA kinase WD40 PF00400.32 KNZ77008.1 - 8.2e-146 469.5 67.3 3.2e-10 40.4 0.1 15.2 15 0 0 15 15 15 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ77008.1 - 1.2e-58 195.4 5.3 0.0018 18.6 0.0 14.5 1 1 14 15 15 15 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ77008.1 - 2.7e-38 129.1 18.4 0.035 14.0 0.2 15.4 15 0 0 15 15 15 11 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KNZ77008.1 - 3.7e-21 75.4 25.8 1.5 7.7 0.0 14.0 1 1 14 15 15 15 10 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KNZ77008.1 - 2e-20 72.6 18.0 0.00013 20.6 0.3 7.3 1 1 5 7 7 7 6 Cytochrome D1 heme domain HARP PF07443.13 KNZ77008.1 - 4.5e-09 35.8 0.1 17 5.1 0.0 9.5 12 0 0 12 12 12 0 HepA-related protein (HARP) Frtz PF11768.8 KNZ77008.1 - 8.6e-08 30.9 0.0 2.8 6.1 0.0 7.2 3 3 6 10 10 10 1 WD repeat-containing and planar cell polarity effector protein Fritz Proteasome_A_N PF10584.9 KNZ77008.1 - 9.4e-08 31.6 26.4 19 5.1 0.0 14.7 16 0 0 16 16 16 0 Proteasome subunit A N-terminal signature WD40_like PF17005.5 KNZ77008.1 - 6.2e-07 29.0 6.6 5.5 6.2 0.1 7.5 5 2 4 9 9 9 1 WD40-like domain GspH PF12019.8 KNZ77008.1 - 1.1e-06 29.0 30.6 17 5.9 0.1 11.8 1 1 9 10 10 10 0 Type II transport protein GspH PLD_C PF12357.8 KNZ77008.1 - 1.3e-06 28.2 0.5 5 7.1 0.0 7.8 9 1 2 11 11 7 1 Phospholipase D C terminal TolB_N PF04052.13 KNZ77008.1 - 0.00051 20.2 0.2 94 3.3 0.0 7.4 10 0 0 10 10 10 0 TolB amino-terminal domain TPP_enzyme_M PF00205.22 KNZ77008.1 - 0.0012 18.6 0.0 22 4.8 0.0 5.5 6 1 1 7 7 7 0 Thiamine pyrophosphate enzyme, central domain DUF5604 PF18300.1 KNZ77008.1 - 0.0015 18.5 14.6 98 3.0 0.5 10.3 11 1 1 12 12 12 0 Domain of unknown function (DUF5604) AcetylCoA_hyd_C PF13336.6 KNZ77008.1 - 0.0095 15.9 10.9 11 5.9 0.0 7.3 7 1 0 8 8 8 0 Acetyl-CoA hydrolase/transferase C-terminal domain DUF5122 PF17164.4 KNZ77008.1 - 0.027 14.8 39.6 8.3 6.8 0.1 12.8 14 0 0 14 14 14 0 Domain of unknown function (DUF5122) beta-propeller TRAP-delta PF05404.12 KNZ77008.1 - 0.034 13.7 6.3 4.3 6.8 0.0 6.0 4 3 5 10 10 10 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Read-through PF16814.5 KNZ77008.1 - 0.082 12.7 12.4 14 5.4 0.1 7.3 4 3 7 11 11 10 0 Read-through domain Surfac_D-trimer PF09006.11 KNZ77008.1 - 0.11 12.4 3.8 27 4.7 0.0 6.7 9 0 0 9 9 8 0 Lung surfactant protein D coiled-coil trimerisation Cadherin_4 PF17803.1 KNZ77008.1 - 0.15 12.7 4.2 53 4.5 0.3 5.1 2 2 2 4 4 4 0 Bacterial cadherin-like domain nos_propeller PF18764.1 KNZ77008.1 - 0.44 10.5 11.0 40 4.2 0.0 7.5 10 1 1 11 11 11 0 Nitrous oxide reductase propeller repeat SRF-TF PF00319.18 KNZ77008.1 - 3.9 7.0 9.0 22 4.6 0.0 6.8 11 0 0 11 11 11 0 SRF-type transcription factor (DNA-binding and dimerisation domain) NACHT PF05729.12 KNZ77009.1 - 2.8e-12 46.9 0.0 5.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KNZ77009.1 - 2.1e-07 31.5 0.0 6.6e-07 29.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KNZ77009.1 - 9.3e-07 28.3 0.0 2.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain PhoU_div PF01865.16 KNZ77009.1 - 0.00055 19.3 0.2 0.0017 17.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function DUF47 APS_kinase PF01583.20 KNZ77009.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KNZ77009.1 - 0.0032 17.9 0.0 0.06 13.8 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ77009.1 - 0.0041 17.4 0.0 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KNZ77009.1 - 0.011 16.1 0.0 0.054 13.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.6 KNZ77009.1 - 0.021 14.6 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KNZ77009.1 - 0.026 15.1 0.0 0.29 11.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 KNZ77009.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KNZ77009.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 KNZ77009.1 - 0.055 14.0 2.8 0.46 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KNZ77009.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 KNZ77009.1 - 0.086 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KNZ77009.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KNZ77009.1 - 0.13 12.8 0.3 0.44 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain ROK PF00480.20 KNZ77009.1 - 0.2 11.1 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 ROK family Laminin_II PF06009.12 KNZ77009.1 - 0.58 10.2 4.1 9.6 6.2 0.1 3.0 3 0 0 3 3 3 0 Laminin Domain II WD40 PF00400.32 KNZ77010.1 - 5.2e-104 337.2 51.9 5e-11 43.0 0.1 10.2 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ77010.1 - 6.6e-42 141.7 5.4 0.0029 17.9 0.0 10.0 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ77010.1 - 1.3e-27 95.1 15.6 0.082 12.9 0.1 10.4 10 0 0 10 10 10 10 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KNZ77010.1 - 2.7e-24 85.8 8.9 0.16 10.9 0.0 9.9 1 1 9 10 10 10 9 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ77010.1 - 2.2e-16 60.3 0.1 0.0019 18.1 0.0 4.4 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A CHAP PF05257.16 KNZ77010.1 - 1.1e-15 57.9 9.8 1.4 9.5 0.0 8.6 1 1 7 8 8 8 4 CHAP domain Cytochrom_D1 PF02239.16 KNZ77010.1 - 1.4e-11 43.5 6.9 0.012 14.1 0.1 4.2 1 1 2 4 4 4 4 Cytochrome D1 heme domain WD40_like PF17005.5 KNZ77010.1 - 1.4e-07 31.2 0.0 4.5 6.5 0.0 6.6 2 1 5 8 8 8 1 WD40-like domain Thioredox_DsbH PF03190.15 KNZ77010.1 - 2.1e-07 31.0 0.2 5.4 6.9 0.0 6.3 3 2 4 7 7 7 1 Protein of unknown function, DUF255 AcetylCoA_hyd_C PF13336.6 KNZ77010.1 - 3.3e-07 30.4 2.4 3.7 7.5 0.0 7.2 2 1 5 8 8 8 1 Acetyl-CoA hydrolase/transferase C-terminal domain HARP PF07443.13 KNZ77010.1 - 4e-06 26.4 0.1 17 5.2 0.0 6.6 9 0 0 9 9 9 0 HepA-related protein (HARP) DUF5604 PF18300.1 KNZ77010.1 - 2.9e-05 23.9 5.2 46 4.1 0.1 8.4 9 1 1 10 10 10 0 Domain of unknown function (DUF5604) Proteasome_A_N PF10584.9 KNZ77010.1 - 4.5e-05 23.0 34.5 4.8 7.0 0.1 13.2 16 0 0 16 16 16 1 Proteasome subunit A N-terminal signature Frtz PF11768.8 KNZ77010.1 - 8.6e-05 21.0 0.0 15 3.8 0.0 5.4 2 2 6 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF5122 PF17164.4 KNZ77010.1 - 0.0023 18.2 11.8 71 3.8 0.0 8.4 10 0 0 10 10 10 0 Domain of unknown function (DUF5122) beta-propeller dbPDZ_assoc PF16610.5 KNZ77010.1 - 0.0082 16.3 15.0 44 4.4 0.0 7.8 7 1 0 8 8 8 0 Unstructured region between two PDZ domains on Dlg5 PLD_C PF12357.8 KNZ77010.1 - 0.018 14.9 1.1 1.2e+02 2.7 0.0 6.0 7 1 1 8 8 6 0 Phospholipase D C terminal DUF3953 PF13129.6 KNZ77010.1 - 0.11 12.3 0.1 57 3.6 0.0 4.1 5 0 0 5 5 4 0 Protein of unknown function (DUF3953) Fur_reg_FbpA PF13076.6 KNZ77010.1 - 0.13 12.0 6.5 65 3.3 0.0 6.2 7 0 0 7 7 7 0 Fur-regulated basic protein A zf-LYAR PF08790.11 KNZ77010.1 - 0.17 11.8 0.2 1.5 8.8 0.1 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF5570 PF17731.1 KNZ77010.1 - 0.65 10.1 29.1 7.6 6.6 0.7 6.8 1 1 6 7 7 7 0 Family of unknown function (DUF5570) Pkinase PF00069.25 KNZ77012.1 - 1.2e-24 87.1 0.0 6.9e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77012.1 - 6.4e-11 42.0 0.0 9.3e-05 21.8 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ77012.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 KNZ77013.1 - 0.0022 17.6 0.1 0.0032 17.1 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KNZ77013.1 - 0.0044 17.0 0.0 0.0067 16.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 KNZ77014.1 - 0.0064 16.8 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ77014.1 - 0.1 13.5 0.0 16 6.5 0.1 3.5 2 1 0 2 2 2 0 WD domain, G-beta repeat DUF1349 PF07081.11 KNZ77015.1 - 0.0038 17.0 0.0 0.0047 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Epimerase PF01370.21 KNZ77016.1 - 0.00024 20.7 0.0 0.00026 20.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KNZ77016.1 - 0.00077 18.7 0.0 0.00085 18.6 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein p450 PF00067.22 KNZ77018.1 - 8e-67 226.0 2.3 1.8e-66 224.8 2.3 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KNZ77019.1 - 7.3e-64 216.2 0.4 5.6e-63 213.3 0.4 2.1 1 1 0 1 1 1 1 Cytochrome P450 Calcipressin PF04847.12 KNZ77023.1 - 1.4e-34 119.4 0.0 2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Calcipressin RRM_1 PF00076.22 KNZ77023.1 - 0.03 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ccdc124 PF06244.12 KNZ77024.1 - 2.6e-28 99.1 18.7 2.6e-28 99.1 18.7 2.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Totivirus_coat PF05518.11 KNZ77024.1 - 1 7.3 5.5 1.3 7.0 5.5 1.1 1 0 0 1 1 1 0 Totivirus coat protein Allexi_40kDa PF05549.11 KNZ77024.1 - 2.2 7.7 4.1 3.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Glyoxalase_3 PF13468.6 KNZ77025.1 - 8.8e-30 104.1 0.0 1.4e-29 103.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Peptidase_S10 PF00450.22 KNZ77026.1 - 2.2e-112 376.5 0.0 3e-112 376.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PP2C PF00481.21 KNZ77029.1 - 9.9e-24 84.4 0.0 2.1e-23 83.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 KNZ77029.1 - 0.00067 19.4 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF21 PF01595.20 KNZ77030.1 - 2.3e-28 99.1 0.2 3.7e-28 98.4 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KNZ77030.1 - 0.0001 22.7 0.0 0.59 10.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain Furin-like_2 PF15913.5 KNZ77030.1 - 0.00043 20.4 4.7 0.00043 20.4 4.7 7.0 1 1 6 7 7 7 3 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 KNZ77030.1 - 0.0041 17.5 7.7 0.0041 17.5 7.7 10.6 10 4 0 10 10 10 2 EGF-like domain VSP PF03302.13 KNZ77030.1 - 0.0099 14.8 148.8 0.015 14.2 31.3 6.3 1 1 5 6 6 6 5 Giardia variant-specific surface protein DUF4381 PF14316.6 KNZ77030.1 - 0.15 12.3 3.3 0.27 11.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Pkinase PF00069.25 KNZ77031.1 - 3.3e-37 128.3 0.0 5.3e-37 127.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77031.1 - 3.6e-15 56.0 0.0 6.1e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ77031.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase tRNA_U5-meth_tr PF05958.11 KNZ77032.1 - 1.8e-16 60.1 0.0 2e-15 56.7 0.0 2.3 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KNZ77032.1 - 6.9e-08 32.2 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KNZ77032.1 - 1.4e-05 25.7 0.0 3.6e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ77032.1 - 0.00025 20.9 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KNZ77032.1 - 0.001 18.6 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KNZ77032.1 - 0.0011 19.5 0.0 0.0035 18.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KNZ77032.1 - 0.0012 18.6 0.1 0.0068 16.2 0.0 2.0 1 1 0 2 2 2 1 Met-10+ like-protein MTS PF05175.14 KNZ77032.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TPMT PF05724.11 KNZ77032.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF4682 PF15733.5 KNZ77032.1 - 0.072 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) Methyltransf_12 PF08242.12 KNZ77032.1 - 0.13 13.0 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cerato-platanin PF07249.12 KNZ77033.1 - 4.2e-38 130.1 0.3 4.8e-38 129.9 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 KNZ77033.1 - 0.012 15.4 0.1 0.015 15.2 0.1 1.3 1 1 0 1 1 1 0 Barwin family LRR_4 PF12799.7 KNZ77034.1 - 0.009 16.4 0.1 8.3 7.0 0.2 4.4 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) VPS53_C PF16854.5 KNZ77035.1 - 0.011 15.6 0.5 0.021 14.7 0.5 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Helitron_like_N PF14214.6 KNZ77036.1 - 6.8e-64 215.6 0.5 8.6e-64 215.3 0.5 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ77036.1 - 0.049 12.7 0.2 0.074 12.1 0.1 1.3 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Hydrolase_4 PF12146.8 KNZ77037.1 - 2.3e-14 53.2 0.4 2.6e-12 46.5 0.2 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ77037.1 - 3.2e-09 37.7 0.3 4.4e-09 37.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ77037.1 - 5.6e-08 32.7 0.9 7.2e-07 29.1 0.4 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KNZ77037.1 - 7.6e-05 22.4 0.0 0.00073 19.1 0.0 2.2 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 KNZ77037.1 - 0.00013 22.0 0.1 0.0014 18.6 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 KNZ77037.1 - 0.0027 17.5 0.1 1.4 8.7 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 KNZ77037.1 - 0.0028 17.2 0.0 0.044 13.3 0.0 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 KNZ77037.1 - 0.0037 17.1 0.1 0.0057 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.12 KNZ77037.1 - 0.0087 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_5 PF12695.7 KNZ77037.1 - 0.01 15.6 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 KNZ77037.1 - 0.049 12.3 0.1 0.084 11.5 0.1 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 KNZ77037.1 - 0.064 13.4 0.1 0.095 12.8 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF829 PF05705.14 KNZ77037.1 - 0.14 12.1 0.0 0.9 9.4 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 KNZ77037.1 - 0.16 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1100 PF06500.11 KNZ77037.1 - 0.17 10.7 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) DUF2974 PF11187.8 KNZ77037.1 - 0.19 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 KNZ77037.1 - 0.19 11.5 0.2 0.46 10.3 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Cu-oxidase PF00394.22 KNZ77039.1 - 5.9e-41 140.2 0.1 2.2e-39 135.1 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ77039.1 - 2.3e-40 137.3 0.6 6.2e-38 129.5 0.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ77039.1 - 1.1e-35 122.3 7.4 1.1e-32 112.6 0.1 3.8 3 1 0 3 3 3 3 Multicopper oxidase Asp_protease_2 PF13650.6 KNZ77041.1 - 0.05 14.2 0.0 0.088 13.5 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 KNZ77041.1 - 0.061 13.1 0.1 0.12 12.2 0.1 1.4 1 1 1 2 2 2 0 Retroviral aspartyl protease ABC_membrane PF00664.23 KNZ77042.1 - 1.2e-52 179.2 17.2 2.2e-34 119.4 4.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ77042.1 - 5.6e-41 140.3 0.0 7.3e-26 91.3 0.0 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ77042.1 - 1.5e-09 37.6 0.6 0.21 11.0 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNZ77042.1 - 7.7e-09 36.3 2.7 6.3e-05 23.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 KNZ77042.1 - 3.7e-08 33.5 1.5 0.0057 16.5 0.3 3.6 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 KNZ77042.1 - 9.4e-08 31.8 2.7 0.0022 17.6 0.8 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KNZ77042.1 - 1.8e-06 27.6 0.1 0.022 14.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KNZ77042.1 - 3.4e-05 24.3 0.9 0.42 11.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KNZ77042.1 - 5.7e-05 23.2 0.2 0.057 13.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 KNZ77042.1 - 0.00022 20.4 0.0 0.11 11.6 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF87 PF01935.17 KNZ77042.1 - 0.00065 19.9 0.5 0.076 13.1 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 KNZ77042.1 - 0.0011 18.4 0.5 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_7 PF12775.7 KNZ77042.1 - 0.0011 18.5 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 KNZ77042.1 - 0.0026 18.1 1.0 1.1 9.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KNZ77042.1 - 0.0027 17.5 0.4 0.19 11.4 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KNZ77042.1 - 0.0052 16.7 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Adeno_IVa2 PF02456.15 KNZ77042.1 - 0.009 14.8 0.1 0.52 9.0 0.0 2.3 2 0 0 2 2 2 1 Adenovirus IVa2 protein E1-E2_ATPase PF00122.20 KNZ77042.1 - 0.016 14.7 1.9 0.34 10.4 0.1 3.4 3 0 0 3 3 3 0 E1-E2 ATPase NACHT PF05729.12 KNZ77042.1 - 0.017 15.1 2.7 6.7 6.6 0.1 3.3 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.14 KNZ77042.1 - 0.02 14.9 1.2 8.1 6.4 0.1 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 KNZ77042.1 - 0.022 14.5 0.5 6.4 6.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 KNZ77042.1 - 0.038 13.6 1.0 3.3 7.3 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 KNZ77042.1 - 0.046 13.4 0.3 19 4.9 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA PF00004.29 KNZ77042.1 - 0.057 13.8 1.0 2.5 8.5 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 KNZ77042.1 - 0.12 11.2 0.2 13 4.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.23 KNZ77042.1 - 0.16 12.1 8.1 1.4 8.9 0.0 3.1 4 0 0 4 4 2 0 Dynamin family Roc PF08477.13 KNZ77042.1 - 0.17 12.1 0.3 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 KNZ77042.1 - 0.17 12.4 0.2 25 5.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 KNZ77042.1 - 0.17 12.0 0.2 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KNZ77042.1 - 2.6 7.8 4.5 10 5.9 0.1 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation BIRC6 PF12356.8 KNZ77046.1 - 0.0071 15.8 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Baculoviral IAP repeat-containing protein 6 LRR_5 PF13306.6 KNZ77047.1 - 0.071 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) DUF892 PF05974.12 KNZ77047.1 - 0.1 12.6 1.8 0.23 11.5 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Thioredoxin_9 PF14595.6 KNZ77047.1 - 0.5 10.1 3.0 0.48 10.2 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin DUF3671 PF12420.8 KNZ77048.1 - 0.28 11.3 1.1 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function Pex24p PF06398.11 KNZ77048.1 - 7.7 5.4 9.8 1.7e+02 0.9 9.2 2.1 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Ist1 PF03398.14 KNZ77049.1 - 4.1e-34 117.9 0.0 7.9e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.18 KNZ77049.1 - 2.7e-09 37.0 0.1 4.6e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PIG-H PF10181.9 KNZ77050.1 - 3.7e-14 52.3 0.0 5.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component RVP_2 PF08284.11 KNZ77051.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4939 PF16297.5 KNZ77052.1 - 0.0015 18.3 0.0 0.002 18.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) TRI5 PF06330.11 KNZ77053.1 - 2e-17 63.1 1.4 2.4e-17 62.9 1.4 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Glutaminase PF04960.15 KNZ77053.1 - 0.059 12.6 0.1 0.099 11.8 0.1 1.3 1 0 0 1 1 1 0 Glutaminase p450 PF00067.22 KNZ77054.1 - 2.8e-53 181.3 0.0 2.5e-39 135.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 RVP_2 PF08284.11 KNZ77056.1 - 0.084 12.6 0.9 0.2 11.4 0.3 1.7 1 1 1 2 2 2 0 Retroviral aspartyl protease TMEM135_C_rich PF15982.5 KNZ77057.1 - 1.9e-05 25.3 1.7 0.25 12.0 0.2 3.4 2 1 1 3 3 3 3 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 KNZ77057.1 - 0.038 14.4 5.9 0.26 11.7 0.1 3.4 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Serglycin PF04360.12 KNZ77058.1 - 0.24 11.3 3.6 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Serglycin AMP-binding PF00501.28 KNZ77059.1 - 3.8e-85 286.0 0.0 1.4e-84 284.2 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ77059.1 - 6.9e-12 46.2 3.4 1.5e-11 45.1 3.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 KNZ77060.1 - 5.6e-17 61.8 23.6 9.1e-07 29.5 1.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ77060.1 - 2e-09 37.6 0.2 5.5e-06 26.6 0.0 4.3 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ77060.1 - 0.0063 16.4 8.3 0.065 13.2 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KNZ77060.1 - 0.053 11.8 0.0 0.069 11.5 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz OB_aCoA_assoc PF01796.17 KNZ77060.1 - 0.057 13.4 1.5 8.7 6.4 0.0 3.3 3 0 0 3 3 3 0 DUF35 OB-fold domain, acyl-CoA-associated WD40_like PF17005.5 KNZ77060.1 - 0.079 12.3 0.0 5.5 6.2 0.0 2.7 3 0 0 3 3 3 0 WD40-like domain Ribosomal_L7Ae PF01248.26 KNZ77061.1 - 2e-25 88.4 2.7 2.3e-25 88.2 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TPR_12 PF13424.6 KNZ77062.1 - 6e-100 327.7 86.2 3.5e-14 52.8 0.4 12.2 2 1 12 14 14 14 14 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ77062.1 - 1.5e-95 310.8 39.9 1.2e-07 31.4 0.0 16.5 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ77062.1 - 8.9e-17 61.5 50.0 3.8e-05 23.2 4.1 5.8 1 1 4 5 5 5 5 MalT-like TPR region TPR_17 PF13431.6 KNZ77062.1 - 4.1e-10 39.3 14.7 9.6 6.8 0.0 12.1 13 0 0 13 13 13 0 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ77062.1 - 2.6e-08 33.4 0.0 8.1e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain TPR_4 PF07721.14 KNZ77062.1 - 3.9e-08 33.2 22.3 2.4 9.0 1.0 11.5 12 0 0 12 12 11 1 Tetratricopeptide repeat AAA_16 PF13191.6 KNZ77062.1 - 2e-05 25.0 2.6 0.00066 20.1 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain Patatin PF01734.22 KNZ77062.1 - 2.5e-05 24.5 0.1 0.00032 20.9 0.1 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase ATPase_2 PF01637.18 KNZ77062.1 - 0.00078 19.4 0.9 0.21 11.5 0.1 3.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea TPR_2 PF07719.17 KNZ77062.1 - 0.0013 18.7 27.8 3.2 8.1 0.1 11.1 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ77062.1 - 0.0019 17.9 25.0 5.4 7.0 0.1 11.1 14 0 0 14 14 13 1 Tetratricopeptide repeat SRP54 PF00448.22 KNZ77062.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 KNZ77062.1 - 0.031 14.6 0.0 0.031 14.6 0.0 3.8 4 1 0 4 4 3 0 AAA domain TniB PF05621.11 KNZ77062.1 - 0.031 13.7 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein TPR_5 PF12688.7 KNZ77062.1 - 0.035 14.3 37.1 0.073 13.3 1.9 7.1 2 2 4 7 7 7 0 Tetratrico peptide repeat TPR_7 PF13176.6 KNZ77062.1 - 0.055 13.5 39.5 3.2 8.0 0.1 12.6 15 0 0 15 15 14 0 Tetratricopeptide repeat Latarcin PF10279.9 KNZ77062.1 - 0.11 12.9 4.3 8.2 6.9 0.2 4.6 3 1 0 3 3 3 0 Latarcin precursor FAST_2 PF08368.12 KNZ77062.1 - 0.12 13.2 0.5 2.7 8.9 0.0 3.3 2 1 0 2 2 2 0 FAST kinase-like protein, subdomain 2 TPR_19 PF14559.6 KNZ77062.1 - 0.17 12.4 44.7 0.54 10.8 1.4 9.5 5 3 4 10 10 10 0 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ77062.1 - 1.3 9.7 29.0 3.2 8.5 0.1 8.7 6 2 4 10 10 10 0 Domain of unknown function (DUF4404) Lge1 PF11488.8 KNZ77062.1 - 1.8 8.8 5.8 9.8 6.4 0.1 3.9 3 0 0 3 3 3 0 Transcriptional regulatory protein LGE1 TPR_16 PF13432.6 KNZ77062.1 - 3.2 8.5 26.1 23 5.7 0.2 9.3 7 4 2 9 9 9 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KNZ77063.1 - 2.5e-48 164.8 0.0 2.8e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GRDP-like PF07173.12 KNZ77065.1 - 2.9e-17 63.6 0.0 1.9e-15 57.7 0.0 2.4 1 1 1 2 2 2 2 Glycine-rich domain-containing protein-like Chitin_synth_2 PF03142.15 KNZ77066.1 - 7.4e-233 773.9 0.1 9.7e-233 773.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 KNZ77066.1 - 1.8e-94 317.3 0.0 3.5e-93 313.1 0.0 2.3 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 KNZ77066.1 - 2.5e-18 66.0 1.9 5.4e-14 52.1 0.0 3.3 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 KNZ77066.1 - 6.4e-18 65.5 0.0 2.9e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DEK_C PF08766.11 KNZ77066.1 - 1.2e-15 57.2 0.1 3.4e-15 55.7 0.1 1.9 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 KNZ77066.1 - 2.9e-15 56.7 2.2 2.9e-15 56.7 2.2 1.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KNZ77066.1 - 9.6e-08 32.0 0.0 0.00058 19.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KNZ77066.1 - 4.3e-05 23.1 0.0 0.0059 16.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 3Beta_HSD PF01073.19 KNZ77070.1 - 2.6e-29 102.1 0.0 7e-29 100.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KNZ77070.1 - 4.9e-13 48.9 0.0 1.2e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KNZ77070.1 - 3e-11 43.2 0.0 7e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KNZ77070.1 - 0.0001 21.5 0.0 0.00096 18.4 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KNZ77070.1 - 0.0012 18.3 0.0 0.0083 15.6 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 KNZ77070.1 - 0.0037 17.2 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KNZ77070.1 - 0.004 17.1 0.0 0.04 13.8 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding RGCC PF15151.6 KNZ77071.1 - 3.2 8.0 5.8 4.7 7.4 5.8 1.2 1 0 0 1 1 1 0 Response gene to complement 32 protein family PIF1 PF05970.14 KNZ77072.1 - 1.1e-79 268.3 0.0 1.2e-79 268.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77072.1 - 4.3e-07 29.9 0.0 5.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ77072.1 - 0.012 15.6 0.0 0.048 13.7 0.0 1.8 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ77072.1 - 0.057 13.1 0.1 0.12 12.1 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 KNZ77072.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.6 KNZ77072.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ77072.1 - 0.17 12.2 0.0 0.25 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.14 KNZ77073.1 - 0.0011 17.0 0.0 0.0013 16.8 0.0 1.0 1 0 0 1 1 1 1 Helicase CTP_synth_N PF06418.14 KNZ77074.1 - 4.5e-121 403.2 0.1 6.1e-121 402.7 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KNZ77074.1 - 2.4e-52 177.5 0.0 3.9e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KNZ77074.1 - 0.003 17.3 0.1 0.043 13.6 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KNZ77074.1 - 0.038 14.1 0.0 0.06 13.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 KNZ77075.1 - 1.5e-34 119.2 0.0 5.6e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ77075.1 - 4.2e-18 65.7 0.1 1.7e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ77075.1 - 0.0036 17.3 0.0 0.2 11.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNZ77075.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KNZ77075.1 - 0.18 12.1 0.2 5.7 7.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain IF4E PF01652.18 KNZ77076.1 - 6.7e-55 185.2 0.0 9.4e-55 184.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CxC2 PF18803.1 KNZ77078.1 - 1e-15 57.8 0.4 1.4e-15 57.4 0.4 1.2 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases NAD_binding_4 PF07993.12 KNZ77080.1 - 5.8e-34 117.4 0.0 8.6e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ77080.1 - 3.8e-22 78.5 0.0 5.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KNZ77080.1 - 8.4e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KNZ77080.1 - 0.02 15.3 0.1 0.062 13.7 0.1 1.9 1 1 0 1 1 1 0 Phosphopantetheine attachment site KR PF08659.10 KNZ77080.1 - 0.031 14.2 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 KR domain GDA1_CD39 PF01150.17 KNZ77083.1 - 3.1e-07 29.4 0.0 3.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DcpS PF05652.12 KNZ77084.1 - 5.8e-12 46.4 0.4 6.7e-09 36.5 0.1 2.4 1 1 1 2 2 2 2 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 KNZ77084.1 - 6.1e-12 46.0 0.0 1.1e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Herpeto_peptide PF14409.6 KNZ77085.1 - 0.18 12.0 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon FAD_binding_4 PF01565.23 KNZ77086.1 - 2e-18 66.5 0.0 5.3e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain End3 PF12761.7 KNZ77087.1 - 0.18 12.0 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Sugar_tr PF00083.24 KNZ77088.1 - 1.4e-87 294.4 17.4 2.1e-87 293.9 17.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ77088.1 - 5.3e-25 88.1 27.4 3.8e-23 82.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2951 PF11166.8 KNZ77089.1 - 2.7 8.3 6.6 8.9 6.6 6.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) TPR_12 PF13424.6 KNZ77092.1 - 8.7e-05 22.7 2.7 0.036 14.4 1.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ77092.1 - 0.014 14.8 0.2 0.13 11.6 0.1 2.3 2 0 0 2 2 2 0 MalT-like TPR region TPR_8 PF13181.6 KNZ77092.1 - 0.094 13.0 9.6 0.54 10.6 0.2 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ77092.1 - 0.18 12.0 12.5 2.3 8.6 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Exo_endo_phos_2 PF14529.6 KNZ77093.1 - 0.00022 21.0 0.2 0.00035 20.4 0.2 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 KNZ77096.1 - 9.7e-08 32.6 1.4 6.4e-07 30.0 1.7 1.8 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase KDZ PF18758.1 KNZ77098.1 - 2.5e-17 63.3 0.1 4.6e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 KNZ77098.1 - 1.1e-07 32.0 0.9 1.1e-07 32.0 0.9 1.7 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KNZ77098.1 - 7.9e-06 26.0 0.8 1.8e-05 24.9 0.8 1.5 1 0 0 1 1 1 1 CxC2 like cysteine cluster associated with KDZ transposases Syntaxin-6_N PF09177.11 KNZ77098.1 - 0.091 13.3 0.3 5.3 7.7 0.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Phage_holin_4_2 PF04020.13 KNZ77099.1 - 3.6 8.3 12.3 9.9 6.9 12.4 1.7 1 1 0 1 1 1 0 Mycobacterial 4 TMS phage holin, superfamily IV ATP_transf PF09830.9 KNZ77100.1 - 9.1e-20 70.6 0.0 1.5e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 KNZ77100.1 - 0.022 14.5 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4922) HIT PF01230.23 KNZ77100.1 - 0.026 15.3 0.1 0.51 11.1 0.0 2.4 2 0 0 2 2 2 0 HIT domain LapA_dom PF06305.11 KNZ77101.1 - 0.051 13.4 0.5 0.083 12.7 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GTF2I PF02946.14 KNZ77101.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 GTF2I-like repeat ILVD_EDD PF00920.21 KNZ77102.1 - 2.6e-138 461.9 0.0 3.1e-138 461.6 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_1 PF00515.28 KNZ77103.1 - 5.4e-19 67.2 0.0 1.8e-06 27.5 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ77103.1 - 8e-16 56.8 0.0 3e-05 23.8 0.1 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ77103.1 - 1.9e-10 40.1 0.0 0.02 15.1 0.0 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ77103.1 - 2.5e-09 37.3 4.8 0.1 12.9 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ77103.1 - 6.7e-09 36.3 0.8 7.3e-05 23.3 0.4 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ77103.1 - 4e-08 32.7 0.1 0.085 12.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ77103.1 - 1.3e-07 31.8 0.3 0.07 14.0 0.0 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ77103.1 - 6.5e-07 28.9 0.3 0.00022 20.9 0.2 3.3 2 1 1 3 3 3 1 TPR repeat TPR_19 PF14559.6 KNZ77103.1 - 3.1e-06 27.6 0.4 0.0097 16.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ77103.1 - 6e-05 23.4 0.0 1 10.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ77103.1 - 0.00072 19.8 0.2 3.3 8.3 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ77103.1 - 0.0015 18.4 1.9 11 6.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ77103.1 - 0.0087 15.3 0.2 0.16 11.2 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ77103.1 - 0.011 15.8 0.0 0.21 11.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ77103.1 - 0.012 15.9 0.7 0.11 12.8 0.5 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 KNZ77103.1 - 0.028 13.8 0.0 0.08 12.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit AAA_11 PF13086.6 KNZ77104.1 - 1.7e-32 113.3 0.2 6.9e-32 111.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KNZ77104.1 - 7.8e-32 110.5 0.0 1.5e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ77104.1 - 1.9e-08 34.3 0.0 4e-06 26.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KNZ77104.1 - 2.8e-08 34.2 0.0 1.1e-06 29.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 KNZ77104.1 - 0.0038 16.6 0.2 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_16 PF13191.6 KNZ77104.1 - 0.034 14.5 1.0 0.22 11.9 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF2075 PF09848.9 KNZ77104.1 - 0.087 12.1 0.0 0.65 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KNZ77104.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 KNZ77104.1 - 0.13 11.8 0.7 0.59 9.6 0.5 2.3 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain ResIII PF04851.15 KNZ77104.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PAC2 PF09754.9 KNZ77105.1 - 3.5e-23 82.7 0.0 4.9e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 PAC2 family NUC173 PF08161.12 KNZ77106.1 - 1.1e-54 185.3 0.0 5.7e-51 173.1 0.0 3.8 5 0 0 5 5 5 2 NUC173 domain HEAT PF02985.22 KNZ77106.1 - 0.00027 20.9 0.4 0.99 9.8 0.0 4.3 5 0 0 5 5 5 2 HEAT repeat MMS19_C PF12460.8 KNZ77106.1 - 0.00033 19.9 5.7 0.0048 16.1 0.2 3.0 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal MetallophosC PF16370.5 KNZ77106.1 - 0.074 13.3 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase DUF2014 PF09427.10 KNZ77106.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) ABC_tran PF00005.27 KNZ77107.1 - 6.4e-43 146.6 0.0 7.1e-24 84.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ77107.1 - 2.9e-13 49.8 0.0 2.6e-05 23.7 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KNZ77107.1 - 9.7e-13 48.6 0.3 0.013 15.3 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Chromo PF00385.24 KNZ77107.1 - 8.3e-09 35.2 0.1 1.6e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 KNZ77107.1 - 1.4e-07 32.2 0.0 0.0013 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KNZ77107.1 - 7.5e-06 26.0 0.0 0.03 14.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KNZ77107.1 - 3.1e-05 23.6 4.2 0.12 12.2 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KNZ77107.1 - 3.8e-05 23.9 0.2 0.26 11.4 0.0 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_18 PF13238.6 KNZ77107.1 - 0.00011 22.8 0.2 0.18 12.4 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KNZ77107.1 - 0.00011 22.5 0.2 0.98 9.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 KNZ77107.1 - 0.00015 22.2 1.6 1.9 8.9 0.0 4.0 4 0 0 4 4 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KNZ77107.1 - 0.00021 21.2 0.2 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 KNZ77107.1 - 0.00038 20.4 0.1 0.18 11.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_28 PF13521.6 KNZ77107.1 - 0.0007 19.9 0.0 0.44 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 KNZ77107.1 - 0.0013 17.8 0.8 0.78 8.7 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 KNZ77107.1 - 0.0023 17.7 0.1 2.7 7.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KNZ77107.1 - 0.0024 18.0 0.2 1.5 8.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain Dopey_N PF04118.14 KNZ77107.1 - 0.0031 16.7 0.0 1.1 8.3 0.0 2.3 1 1 1 2 2 2 1 Dopey, N-terminal AAA_30 PF13604.6 KNZ77107.1 - 0.0032 17.2 0.2 2.8 7.6 0.1 3.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KNZ77107.1 - 0.0087 15.7 1.3 10 5.6 0.2 3.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KNZ77107.1 - 0.011 15.9 0.1 6.1 7.1 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 KNZ77107.1 - 0.012 14.4 0.0 1.1 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KNZ77107.1 - 0.013 15.5 0.2 15 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 KNZ77107.1 - 0.014 15.8 0.2 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KNZ77107.1 - 0.016 14.4 0.0 6.7 5.8 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 KNZ77107.1 - 0.021 14.6 0.3 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Adaptin_N PF01602.20 KNZ77107.1 - 0.023 13.3 2.4 0.22 10.1 1.5 2.1 1 1 0 2 2 2 0 Adaptin N terminal region AAA_15 PF13175.6 KNZ77107.1 - 0.029 14.1 0.4 3.8 7.1 0.2 2.3 2 0 0 2 2 2 0 AAA ATPase domain MMS19_C PF12460.8 KNZ77107.1 - 0.04 13.1 6.0 0.053 12.6 1.1 2.5 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal AAA_7 PF12775.7 KNZ77107.1 - 0.042 13.4 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KNZ77107.1 - 0.046 13.8 0.0 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Dynamin family HEAT PF02985.22 KNZ77107.1 - 0.048 13.9 11.0 0.96 9.9 0.2 5.9 6 0 0 6 6 5 0 HEAT repeat G-alpha PF00503.20 KNZ77107.1 - 0.049 12.8 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.21 KNZ77107.1 - 0.074 12.5 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family IFRD PF05004.13 KNZ77107.1 - 0.083 12.0 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) 4HB PF17947.1 KNZ77107.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Four helical bundle domain AAA_27 PF13514.6 KNZ77107.1 - 0.097 12.3 0.0 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.8 KNZ77107.1 - 0.11 10.0 1.8 4.3 4.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ATPase_2 PF01637.18 KNZ77107.1 - 0.13 12.2 0.9 23 4.8 0.1 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 KNZ77107.1 - 0.15 11.3 0.3 3.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 KNZ77107.1 - 0.16 11.9 0.1 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 KNZ77107.1 - 0.17 11.7 0.1 18 5.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 KNZ77107.1 - 0.17 11.8 0.9 13 5.7 0.2 3.2 3 0 0 3 3 3 0 NTPase HEAT_EZ PF13513.6 KNZ77107.1 - 0.9 10.1 10.3 0.48 11.0 0.9 4.0 2 2 2 4 4 3 0 HEAT-like repeat Homeodomain PF00046.29 KNZ77108.1 - 5.5e-15 55.0 5.1 1.2e-14 53.9 5.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KNZ77108.1 - 0.0013 18.6 0.2 0.0029 17.5 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain KIF1B PF12423.8 KNZ77108.1 - 0.83 10.1 3.4 9 6.8 0.2 2.7 2 0 0 2 2 2 0 Kinesin protein 1B zf-C2H2 PF00096.26 KNZ77109.1 - 2.3e-05 24.6 0.3 2.3e-05 24.6 0.3 2.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ77109.1 - 0.00033 21.3 1.7 0.0015 19.2 0.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ77109.1 - 0.00082 19.7 7.9 0.0024 18.2 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger double domain BolA PF01722.18 KNZ77110.1 - 1.1e-17 64.0 0.6 1.7e-17 63.4 0.6 1.3 1 1 0 1 1 1 1 BolA-like protein PIF1 PF05970.14 KNZ77114.1 - 2.9e-24 85.9 0.0 3.7e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DNA_ligase_A_M PF01068.21 KNZ77116.1 - 7.3e-44 149.9 0.0 1.7e-43 148.7 0.0 1.6 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KNZ77116.1 - 3.7e-32 112.0 0.0 8.5e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KNZ77116.1 - 3.8e-09 37.0 0.0 5.3e-07 30.2 0.0 2.9 1 1 1 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KNZ77116.1 - 0.034 14.5 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA ligase TPR_19 PF14559.6 KNZ77117.1 - 0.14 12.7 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PhoD PF09423.10 KNZ77118.1 - 6.1e-90 301.7 0.1 1.7e-89 300.3 0.1 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 KNZ77118.1 - 1.3e-21 76.9 0.0 2.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 KNZ77118.1 - 0.0011 19.5 0.0 0.0024 18.4 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PIF1 PF05970.14 KNZ77119.1 - 7.3e-17 61.6 0.2 7.8e-17 61.5 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.18 KNZ77119.1 - 0.013 15.2 0.1 0.013 15.2 0.1 1.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KNZ77119.1 - 0.027 14.0 0.1 0.031 13.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KNZ77119.1 - 0.029 14.1 0.0 0.029 14.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KNZ77119.1 - 0.03 14.4 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 KNZ77119.1 - 0.047 14.1 0.0 0.047 14.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KNZ77119.1 - 0.063 13.3 0.0 0.063 13.3 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KNZ77119.1 - 0.12 12.7 0.0 0.14 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA helicase DUF2791 PF10923.8 KNZ77119.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_22 PF13401.6 KNZ77119.1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KNZ77119.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KNZ77119.1 - 0.2 10.8 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain PIF1 PF05970.14 KNZ77120.1 - 3.2e-09 36.4 0.0 4.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77120.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_2 PF03668.15 KNZ77122.1 - 2.5e-05 23.7 0.0 4.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 P-loop ATPase protein family Zn_clus PF00172.18 KNZ77123.1 - 7.9e-08 32.3 11.3 7.9e-08 32.3 11.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.11 KNZ77123.1 - 0.08 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAD_binding_4 PF01565.23 KNZ77124.1 - 1.8e-29 102.2 2.4 3.3e-29 101.4 2.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KNZ77124.1 - 1.8e-16 59.9 0.3 3.1e-16 59.2 0.3 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 KNZ77124.1 - 0.061 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Big_3_5 PF16640.5 KNZ77124.1 - 0.18 12.0 4.7 9.5 6.5 0.1 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) FAD_binding_4 PF01565.23 KNZ77125.1 - 2.2e-25 89.0 1.6 4.1e-25 88.1 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KNZ77125.1 - 1.3e-11 44.4 2.1 1.4e-11 44.3 1.0 1.7 2 0 0 2 2 2 1 Berberine and berberine like Beta-lactamase PF00144.24 KNZ77126.1 - 1.2e-09 37.8 0.1 1.1e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase FA_desaturase PF00487.24 KNZ77129.1 - 2.4e-24 86.5 25.6 3.7e-24 86.0 25.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KNZ77129.1 - 0.003 17.8 0.0 0.0051 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 KNZ77130.1 - 6.8e-22 78.5 31.0 1.1e-21 77.9 31.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KNZ77130.1 - 2.7e-05 24.4 0.0 5.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) UvrD_C_2 PF13538.6 KNZ77133.1 - 0.064 13.1 0.0 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain RT_RNaseH_2 PF17919.1 KNZ77134.1 - 9.7e-12 44.8 0.1 2.3e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ77134.1 - 8.4e-11 42.1 0.1 1.8e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIF1 PF05970.14 KNZ77134.1 - 3.4e-07 29.8 0.0 4.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77134.1 - 0.00037 20.3 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ77134.1 - 0.012 15.9 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-C2H2_10 PF16588.5 KNZ77137.1 - 0.27 11.0 1.8 0.51 10.1 1.8 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KNZ77137.1 - 0.41 10.8 1.9 0.7 10.1 1.9 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF359 PF04019.12 KNZ77140.1 - 0.59 9.8 3.0 1.1 8.9 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF359) CENP-H PF05837.12 KNZ77140.1 - 1.8 9.0 5.8 2.6 8.5 2.0 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF3109 PF11307.8 KNZ77142.1 - 0.14 12.0 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) ECH_1 PF00378.20 KNZ77143.1 - 5.2e-40 137.3 0.0 5.8e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ77143.1 - 1.8e-16 60.6 0.2 1.2e-13 51.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase CLP_protease PF00574.23 KNZ77143.1 - 0.037 13.9 0.1 5.5 6.8 0.0 2.2 1 1 1 2 2 2 0 Clp protease Sec10 PF07393.11 KNZ77144.1 - 3.2e-222 739.9 0.0 4.2e-222 739.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Peptidase_S46 PF10459.9 KNZ77144.1 - 0.0042 15.8 0.3 0.007 15.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase S46 GNAT_like PF18407.1 KNZ77144.1 - 0.9 9.9 2.7 0.76 10.2 0.1 2.2 2 0 0 2 2 2 0 GCN5-related N-acetyltransferase like domain RIX1 PF08167.12 KNZ77145.1 - 6.4e-39 133.6 5.8 6.4e-39 133.6 5.8 2.8 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis BTAD PF03704.17 KNZ77146.1 - 0.038 14.4 0.2 0.053 14.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_19 PF14559.6 KNZ77146.1 - 0.071 13.6 0.1 2.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.12 KNZ77146.1 - 0.12 11.9 0.2 0.31 10.5 0.2 1.6 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor TAF1_subA PF14929.6 KNZ77146.1 - 0.16 11.4 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A DUF5102 PF17104.5 KNZ77147.1 - 5.2e-68 230.2 0.0 6.3e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) RNA_pol_Rpb1_5 PF04998.17 KNZ77148.1 - 4.2e-88 295.3 0.0 3.1e-87 292.4 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KNZ77148.1 - 4.4e-58 196.2 0.0 7.8e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KNZ77148.1 - 1.4e-36 125.8 0.0 4.3e-36 124.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KNZ77148.1 - 4.2e-30 105.2 0.6 4.2e-22 78.9 0.0 3.9 3 2 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KNZ77148.1 - 1.2e-20 73.5 0.0 3.6e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.12 KNZ77148.1 - 2.3 6.3 15.1 3.7 5.6 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoporin_FG PF13634.6 KNZ77149.1 - 0.066 14.1 1.1 10 7.0 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin FG repeat region PBP PF01161.20 KNZ77151.1 - 4.6e-15 56.1 0.1 7.1e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RRM_1 PF00076.22 KNZ77152.1 - 1.2e-18 66.7 0.1 1.2e-18 66.7 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNZ77152.1 - 3.5e-08 33.1 0.0 3.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KNZ77152.1 - 0.029 14.4 0.1 0.047 13.7 0.1 1.4 1 1 0 1 1 1 0 RNA binding motif RRM_8 PF11835.8 KNZ77152.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 1 1 2 2 2 0 RRM-like domain RRM_occluded PF16842.5 KNZ77152.1 - 0.078 12.8 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Mito_carr PF00153.27 KNZ77153.1 - 1.8e-64 213.7 6.2 1e-23 83.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 KNZ77154.1 - 2.3e-43 148.0 0.1 4.1e-43 147.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ77154.1 - 2.5e-31 108.3 0.1 1e-30 106.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 KNZ77154.1 - 0.0007 20.0 0.1 0.019 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KNZ77154.1 - 0.0009 19.3 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ77154.1 - 0.033 13.9 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KNZ77154.1 - 0.071 13.4 0.5 0.39 11.0 0.5 2.1 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 KNZ77154.1 - 0.14 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF1871 PF08958.10 KNZ77154.1 - 0.17 12.2 0.4 0.77 10.1 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) DUF3449 PF11931.8 KNZ77155.1 - 2.3e-68 229.6 1.0 9.7e-34 116.8 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KNZ77155.1 - 1.1e-24 86.7 3.4 2.6e-24 85.5 2.4 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KNZ77155.1 - 1.3e-08 34.6 0.0 2.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain Laps PF10169.9 KNZ77155.1 - 0.11 13.1 0.2 0.39 11.3 0.2 1.9 1 0 0 1 1 1 0 Learning-associated protein Syja_N PF02383.18 KNZ77156.1 - 1.5e-70 238.1 0.0 2e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 KNZ77156.1 - 3e-11 43.3 0.0 6.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Erv26 PF04148.13 KNZ77157.1 - 3.5e-65 219.7 6.8 4e-65 219.5 6.8 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Snf7 PF03357.21 KNZ77158.1 - 6.7e-10 38.8 13.5 8.9e-10 38.4 13.5 1.2 1 0 0 1 1 1 1 Snf7 DUF2857 PF11198.8 KNZ77158.1 - 0.011 15.6 1.5 0.27 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Ist1 PF03398.14 KNZ77158.1 - 0.015 15.2 4.4 0.022 14.7 4.4 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 KNZ77158.1 - 0.025 14.2 0.5 0.049 13.3 0.1 1.6 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase MMR_HSR1 PF01926.23 KNZ77160.1 - 1.4e-17 63.8 0.1 1.6e-14 54.0 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ77160.1 - 1.7e-09 37.8 0.2 8.4e-09 35.5 0.1 2.1 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 KNZ77160.1 - 2.3e-08 33.7 0.2 7.1e-06 25.6 0.1 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 KNZ77160.1 - 4.1e-05 23.2 0.0 0.0031 17.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KNZ77160.1 - 0.00029 20.9 0.4 0.25 11.4 0.1 2.8 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 KNZ77160.1 - 0.007 15.4 0.1 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 KNZ77160.1 - 0.011 15.9 0.2 3.6 7.8 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KNZ77160.1 - 0.04 13.5 0.1 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KNZ77160.1 - 0.043 14.2 0.0 0.83 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 KNZ77160.1 - 0.12 12.9 0.0 0.58 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 KNZ77160.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 AIG1 family Septin PF00735.18 KNZ77160.1 - 0.18 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Septin Abhydrolase_1 PF00561.20 KNZ77161.1 - 7.9e-39 133.8 0.0 2.2e-38 132.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KNZ77161.1 - 0.00042 20.0 0.0 0.00073 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KNZ77161.1 - 0.081 12.7 0.1 0.4 10.4 0.1 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase zf-H2C2_2 PF13465.6 KNZ77162.1 - 8e-09 35.5 7.9 8e-08 32.4 0.2 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KNZ77162.1 - 3.4e-08 33.5 18.4 2.8e-05 24.3 0.3 4.5 4 1 0 4 4 4 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 KNZ77162.1 - 4.8e-07 30.3 6.8 0.023 15.3 3.4 3.2 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 KNZ77162.1 - 0.0028 18.0 2.8 3.6 8.1 0.0 3.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KNZ77162.1 - 0.0048 17.6 10.4 0.033 15.0 0.3 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KNZ77162.1 - 0.04 13.9 5.2 0.16 12.0 0.1 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 KNZ77162.1 - 0.055 13.8 5.8 2.1 8.7 0.8 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 KNZ77162.1 - 0.79 9.9 8.8 1.1 9.5 2.2 3.3 3 1 0 3 3 3 0 Zic proteins zinc finger domain Snf7 PF03357.21 KNZ77163.1 - 3.8e-45 153.6 13.9 4.3e-45 153.4 13.9 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 KNZ77163.1 - 0.031 14.7 5.9 2.3 8.7 0.3 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.11 KNZ77163.1 - 0.055 13.7 1.9 0.11 12.7 1.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF2730 PF10805.8 KNZ77163.1 - 0.079 13.1 0.3 0.079 13.1 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FlxA PF14282.6 KNZ77163.1 - 0.21 11.6 10.0 0.094 12.7 6.1 2.1 1 1 1 2 2 2 0 FlxA-like protein FlaC_arch PF05377.11 KNZ77163.1 - 0.27 11.7 6.0 0.73 10.3 0.1 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Macoilin PF09726.9 KNZ77163.1 - 0.53 8.8 9.8 0.64 8.5 9.8 1.0 1 0 0 1 1 1 0 Macoilin family GPS2_interact PF15784.5 KNZ77163.1 - 0.6 10.6 4.4 0.55 10.7 1.8 2.2 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain DHR10 PF18595.1 KNZ77163.1 - 1.1 9.3 17.3 0.88 9.6 2.8 3.2 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain XhlA PF10779.9 KNZ77163.1 - 1.3 9.3 5.8 15 5.9 0.1 2.9 2 1 0 3 3 3 0 Haemolysin XhlA Atg14 PF10186.9 KNZ77163.1 - 1.5 7.8 5.7 2.1 7.4 5.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BST2 PF16716.5 KNZ77163.1 - 1.6 9.4 8.9 7.5 7.2 0.1 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Rx_N PF18052.1 KNZ77163.1 - 2 8.7 6.9 15 5.9 0.3 2.6 1 1 0 2 2 2 0 Rx N-terminal domain FapA PF03961.13 KNZ77163.1 - 3.2 6.3 9.6 0.98 7.9 1.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Aldedh PF00171.22 KNZ77164.1 - 2.5e-134 448.3 0.8 9e-118 393.7 0.2 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 KNZ77164.1 - 0.0025 16.9 0.1 0.0084 15.2 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RCC1 PF00415.18 KNZ77165.1 - 1.4e-57 192.1 17.2 2.2e-09 37.8 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KNZ77165.1 - 1.7e-36 123.3 43.2 8.8e-08 31.8 0.3 8.1 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 KNZ77165.1 - 0.091 13.2 0.4 31 5.0 0.0 3.6 4 0 0 4 4 4 0 SUKH-3 immunity protein 2OG-FeII_Oxy PF03171.20 KNZ77167.1 - 5.9e-18 65.2 0.0 8.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BTB PF00651.31 KNZ77169.1 - 8.9e-07 29.1 0.0 2.9e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Spermine_synth PF01564.17 KNZ77170.1 - 2.9e-05 23.6 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain DUF2105 PF09878.9 KNZ77170.1 - 0.086 12.6 1.0 0.15 11.8 1.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) p25-alpha PF05517.12 KNZ77171.1 - 0.31 11.2 0.0 0.51 10.5 0.0 1.3 1 0 0 1 1 1 0 p25-alpha GTP_cyclohydro2 PF00925.20 KNZ77172.1 - 1.3e-56 190.7 0.0 1.9e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Glyco_hydro_17 PF00332.18 KNZ77173.1 - 3.7e-10 39.9 2.7 5e-10 39.5 0.3 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 EphA2_TM PF14575.6 KNZ77173.1 - 0.057 14.3 0.0 0.14 13.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3552 PF12072.8 KNZ77173.1 - 0.27 10.6 1.1 0.57 9.6 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Vps5 PF09325.10 KNZ77174.1 - 7.6e-16 58.4 1.2 1.1e-15 57.8 1.2 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 KNZ77174.1 - 1.1e-10 41.5 0.4 2.8e-10 40.2 0.0 1.8 2 0 0 2 2 2 1 PX domain TruD PF01142.18 KNZ77174.1 - 1.2 7.9 5.1 12 4.6 1.9 2.1 1 1 1 2 2 2 0 tRNA pseudouridine synthase D (TruD) Peptidase_M24 PF00557.24 KNZ77175.1 - 1.8e-11 44.2 0.0 5.3e-11 42.6 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Pex14_N PF04695.13 KNZ77176.1 - 1.6e-08 35.4 0.1 1.6e-08 35.4 0.1 3.3 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha-amylase_C PF02806.18 KNZ77177.1 - 3.9e-21 75.3 0.0 1.9e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KNZ77177.1 - 2.8e-19 69.3 0.0 6.8e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KNZ77177.1 - 2.7e-14 53.5 0.1 7.7e-10 38.9 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Iso_dh PF00180.20 KNZ77178.1 - 3.7e-119 398.0 0.0 4.2e-119 397.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PIN_6 PF17146.4 KNZ77179.1 - 6.2e-26 90.7 0.0 1.5e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 KNZ77179.1 - 1.2e-23 83.0 0.2 2.2e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.6 KNZ77179.1 - 0.062 12.7 0.4 0.25 10.8 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain Pilosulin PF17499.2 KNZ77179.1 - 0.17 12.1 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Ant venom peptides zinc_ribbon_2 PF13240.6 KNZ77179.1 - 0.99 9.2 4.2 2.7 7.8 4.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain P21-Arc PF04062.14 KNZ77180.1 - 1.9e-76 255.9 0.0 2.1e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Ion_trans PF00520.31 KNZ77181.1 - 0.068 12.4 20.1 0.063 12.5 15.8 2.6 2 1 0 2 2 2 0 Ion transport protein Sld5 PF05916.11 KNZ77182.1 - 4.9e-22 78.4 0.2 7.5e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein Haspin_kinase PF12330.8 KNZ77183.1 - 2.2e-56 191.4 0.0 3.3e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain SKN1 PF03935.15 KNZ77184.1 - 2e-188 626.9 1.9 2.3e-188 626.7 1.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) F-box PF00646.33 KNZ77185.1 - 1.1e-06 28.3 1.6 1.1e-06 28.3 1.6 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KNZ77185.1 - 7.2e-05 22.6 0.7 7.2e-05 22.6 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 KNZ77185.1 - 0.026 14.4 0.3 0.054 13.4 0.3 1.5 1 0 0 1 1 1 0 F-box zf-C2H2 PF00096.26 KNZ77186.1 - 2.5e-07 30.7 23.1 0.00025 21.3 5.3 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ77186.1 - 4.7e-07 29.9 14.3 0.0013 19.0 1.6 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ77186.1 - 0.00013 22.5 15.2 0.042 14.7 4.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger UCH PF00443.29 KNZ77187.1 - 1.7e-49 168.7 0.0 2.2e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ77187.1 - 3.1e-21 76.3 0.0 8.7e-21 74.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 KNZ77187.1 - 0.013 15.0 2.0 0.081 12.4 2.0 2.2 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF2175 PF09943.9 KNZ77187.1 - 0.087 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) DZR PF12773.7 KNZ77187.1 - 2 8.5 4.8 11 6.1 1.5 3.0 2 1 0 2 2 2 0 Double zinc ribbon DUF4551 PF15087.6 KNZ77187.1 - 6.8 5.4 5.1 9.7 4.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PP2C PF00481.21 KNZ77188.1 - 3.1e-28 99.1 0.0 5.6e-25 88.4 0.0 2.3 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 KNZ77188.1 - 1.2e-06 28.3 0.0 7.6e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C ACT_7 PF13840.6 KNZ77190.1 - 8.1e-14 51.2 0.3 8.6e-13 47.9 0.0 2.3 1 1 1 2 2 2 2 ACT domain adh_short PF00106.25 KNZ77192.1 - 5.3e-41 140.2 0.0 7.8e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ77192.1 - 8.3e-26 91.0 0.0 1.3e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ77192.1 - 1.3e-10 41.4 0.1 3.1e-09 37.0 0.1 2.1 1 1 0 1 1 1 1 KR domain DUF4668 PF15701.5 KNZ77192.1 - 0.0082 16.0 1.0 0.0082 16.0 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4668) Epimerase PF01370.21 KNZ77192.1 - 0.19 11.2 0.1 0.76 9.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RNA_polI_A14 PF08203.11 KNZ77193.1 - 0.052 14.3 0.0 0.069 13.9 0.0 1.3 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 CAP PF00188.26 KNZ77195.1 - 4.8e-08 33.9 0.6 5.6e-08 33.7 0.6 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Prefoldin_2 PF01920.20 KNZ77196.1 - 3.5e-20 71.9 1.3 4.5e-20 71.6 1.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Phage_Mu_Gam PF07352.12 KNZ77196.1 - 0.0081 16.1 0.1 0.015 15.2 0.1 1.5 1 1 0 1 1 1 1 Bacteriophage Mu Gam like protein DUF4407 PF14362.6 KNZ77196.1 - 0.023 14.1 1.1 0.028 13.8 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 KNZ77196.1 - 0.027 14.8 0.9 3.4 8.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) CENP-H PF05837.12 KNZ77196.1 - 0.032 14.7 1.5 2.8 8.4 0.5 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 KNZ77196.1 - 0.13 12.3 0.7 15 5.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KNZ77196.1 - 0.18 11.9 4.6 0.36 11.0 1.7 2.0 2 0 0 2 2 2 0 Tropomyosin like Fer4 PF00037.27 KNZ77197.1 - 6.4e-14 51.1 17.5 2e-08 33.7 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KNZ77197.1 - 1.3e-12 48.1 9.4 2e-12 47.5 9.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KNZ77197.1 - 1e-10 42.4 9.2 1.7e-05 25.6 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KNZ77197.1 - 8.8e-10 38.6 5.1 0.00022 21.3 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KNZ77197.1 - 4e-09 36.4 20.8 1.7e-06 28.1 11.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KNZ77197.1 - 1.4e-08 35.1 3.5 0.00016 22.0 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KNZ77197.1 - 2e-08 34.3 9.9 3.3e-08 33.6 9.9 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KNZ77197.1 - 5e-07 29.5 17.8 0.00044 20.2 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KNZ77197.1 - 1.4e-06 28.1 11.7 0.0026 17.8 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KNZ77197.1 - 7.8e-06 26.0 11.0 0.00036 20.8 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KNZ77197.1 - 0.00011 22.7 10.5 0.011 16.2 12.2 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 KNZ77197.1 - 0.0021 18.6 11.7 0.17 12.5 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I SF1-HH PF16275.5 KNZ77197.1 - 0.0027 18.0 0.2 0.0066 16.8 0.2 1.7 1 1 0 1 1 1 1 Splicing factor 1 helix-hairpin domain c-SKI_SMAD_bind PF08782.10 KNZ77197.1 - 0.012 15.8 5.8 0.66 10.2 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KNZ77197.1 - 0.051 13.8 8.9 9.8 6.4 8.9 2.3 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 KNZ77197.1 - 0.26 12.3 16.3 0.39 11.8 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KNZ77197.1 - 0.48 11.3 11.9 1.5 9.8 1.4 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain EPF PF17181.4 KNZ77197.1 - 0.75 9.9 5.5 0.49 10.4 0.5 2.3 2 0 0 2 2 2 0 Epidermal patterning factor proteins ETF_QO PF05187.13 KNZ77197.1 - 0.9 9.7 7.0 3.5 7.8 0.7 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S ZapB PF06005.12 KNZ77198.1 - 0.24 11.8 1.2 0.38 11.2 1.2 1.2 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 KNZ77198.1 - 0.32 11.1 2.4 0.68 10.1 2.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor GRIM-19 PF06212.12 KNZ77199.1 - 1.2e-27 96.4 0.0 1.3e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein HMG_box_2 PF09011.10 KNZ77200.1 - 7.2e-15 55.3 11.5 3.1e-07 30.9 3.5 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 KNZ77200.1 - 1.4e-13 51.0 16.8 3.3e-06 27.4 6.7 3.4 2 1 0 2 2 2 2 HMG (high mobility group) box Acetyltransf_10 PF13673.7 KNZ77201.1 - 1.6e-10 41.0 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ77201.1 - 2.7e-05 24.4 0.0 3.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ77201.1 - 4.6e-05 23.8 0.0 5.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KNZ77201.1 - 0.023 15.4 0.0 1.5 9.5 0.0 2.4 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain PPR_2 PF13041.6 KNZ77202.1 - 2.7e-37 126.7 2.3 5.4e-12 45.7 0.0 10.1 8 2 3 11 11 11 4 PPR repeat family PPR PF01535.20 KNZ77202.1 - 6.3e-31 104.4 7.2 0.00016 21.7 0.0 13.7 15 0 0 15 15 15 6 PPR repeat PPR_3 PF13812.6 KNZ77202.1 - 2.7e-27 94.6 0.1 6.9e-09 35.7 0.0 8.8 9 2 2 11 11 11 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 KNZ77202.1 - 3.8e-21 74.5 5.3 6.7e-06 25.7 0.0 8.8 9 0 0 9 9 9 3 PPR repeat PPR_long PF17177.4 KNZ77202.1 - 2.6e-14 53.1 0.1 1.4e-07 31.1 0.1 4.6 2 1 2 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 KNZ77202.1 - 7.1e-05 23.3 6.8 33 5.7 0.0 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat ATP13 PF12921.7 KNZ77202.1 - 0.00058 19.7 0.0 0.3 11.0 0.0 4.0 3 1 0 3 3 3 1 Mitochondrial ATPase expression TPR_8 PF13181.6 KNZ77202.1 - 0.046 13.9 0.1 53 4.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4407 PF14362.6 KNZ77202.1 - 0.076 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ECSIT PF06239.11 KNZ77202.1 - 0.087 11.9 0.1 0.99 8.5 0.0 2.6 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_4 PF07721.14 KNZ77202.1 - 0.19 12.5 12.1 0.24 12.1 1.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ77202.1 - 0.24 12.1 4.6 3.9 8.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Velvet PF11754.8 KNZ77203.1 - 1.7e-80 270.6 1.6 1.1e-79 268.0 1.6 1.9 1 1 0 1 1 1 1 Velvet factor SOG2 PF10428.9 KNZ77203.1 - 7.5 5.6 11.7 11 5.1 11.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein ArfGap PF01412.18 KNZ77204.1 - 5.2e-33 113.6 0.4 9.8e-33 112.7 0.4 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Carboxyl_trans PF01039.22 KNZ77205.1 - 2.8e-132 441.9 0.0 4.9e-132 441.1 0.0 1.3 1 1 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 KNZ77205.1 - 0.00023 20.7 4.0 0.0081 15.7 0.1 2.5 3 0 0 3 3 3 2 Malonate decarboxylase gamma subunit (MdcE) DNA_mis_repair PF01119.19 KNZ77206.1 - 1.8e-08 34.1 0.0 4e-06 26.5 0.1 2.9 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KNZ77206.1 - 1.3e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KNZ77206.1 - 1.4e-06 28.1 0.0 1.3e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 KNZ77206.1 - 2.2e-05 24.9 0.0 4.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MITF_TFEB_C_3_N PF15951.5 KNZ77206.1 - 0.0087 16.7 0.4 0.0087 16.7 0.4 1.9 2 0 0 2 2 2 1 MITF/TFEB/TFEC/TFE3 N-terminus SBDS PF01172.18 KNZ77207.1 - 4.9e-21 74.6 0.1 6.1e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein TAF6_C PF07571.13 KNZ77208.1 - 8e-16 58.1 0.0 2.4e-15 56.6 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KNZ77208.1 - 9.3e-16 57.8 2.4 3.9e-07 30.1 0.3 2.6 1 1 1 2 2 2 2 TATA box binding protein associated factor (TAF) Histone PF00125.24 KNZ77208.1 - 0.068 13.5 0.9 0.16 12.3 0.1 2.0 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KNZ77208.1 - 0.15 12.1 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 Bromodomain associated Phostensin_N PF13916.6 KNZ77208.1 - 0.21 12.0 4.7 0.13 12.6 2.1 2.0 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal HEAT_EZ PF13513.6 KNZ77208.1 - 3.1 8.4 12.7 3.2 8.3 0.1 4.6 4 1 1 5 5 5 0 HEAT-like repeat DUF1664 PF07889.12 KNZ77210.1 - 0.0036 17.3 3.2 0.0066 16.5 1.5 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF1461 PF07314.11 KNZ77210.1 - 0.086 12.7 0.1 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Pkinase PF00069.25 KNZ77211.1 - 1.8e-10 40.7 0.0 7.1e-08 32.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77211.1 - 0.00034 20.0 0.0 0.0068 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KNZ77211.1 - 0.036 13.1 0.1 0.061 12.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIF1 PF05970.14 KNZ77213.1 - 4.3e-51 174.2 0.1 5.2e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77213.1 - 0.00032 20.5 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ77213.1 - 0.016 15.2 0.0 0.073 13.1 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 KNZ77214.1 - 7.9e-30 104.2 0.5 9.2e-30 104.0 0.5 1.1 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ77214.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UvrD_C_2 PF13538.6 KNZ77214.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SNF5 PF04855.12 KNZ77215.1 - 1.6e-75 253.9 0.1 1.5e-74 250.8 0.1 1.9 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 AFG1_ATPase PF03969.16 KNZ77216.1 - 2.1e-89 300.0 0.0 6.4e-86 288.5 0.0 2.0 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 KNZ77216.1 - 1.5e-05 25.4 0.0 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KNZ77216.1 - 0.00035 21.0 0.0 0.0013 19.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ77216.1 - 0.0075 16.5 0.1 0.037 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 KNZ77216.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 KNZ77216.1 - 0.064 13.3 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KNZ77216.1 - 0.096 12.5 0.1 0.27 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein TsaE PF02367.17 KNZ77216.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UreF PF01730.16 KNZ77217.1 - 2e-25 89.9 0.2 3.2e-25 89.2 0.2 1.2 1 0 0 1 1 1 1 UreF JAB PF01398.21 KNZ77218.1 - 4e-21 75.2 0.0 7.6e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KNZ77218.1 - 9.6e-20 71.1 0.2 1.5e-19 70.4 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Tom7 PF08038.12 KNZ77219.1 - 2.1e-13 49.7 0.4 3.4e-13 49.0 0.4 1.3 1 0 0 1 1 1 1 TOM7 family RNF220 PF15926.5 KNZ77220.1 - 4.4e-16 59.3 4.3 4.4e-16 59.3 4.3 2.7 2 1 1 3 3 3 2 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 KNZ77220.1 - 1.6e-08 34.3 14.2 1.6e-08 34.3 14.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ77220.1 - 1.4e-05 24.9 20.5 0.0001 22.2 12.9 3.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KNZ77220.1 - 0.00047 20.0 21.3 0.00049 19.9 12.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ77220.1 - 0.00093 19.0 14.5 0.00093 19.0 14.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.12 KNZ77220.1 - 0.0011 19.2 4.6 2.2 8.7 0.1 3.8 4 0 0 4 4 4 2 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 KNZ77220.1 - 0.0034 17.4 8.4 0.0034 17.4 8.4 3.7 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 KNZ77220.1 - 0.0046 17.2 16.5 0.0046 17.2 16.5 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_6 PF14835.6 KNZ77220.1 - 0.019 14.8 11.1 0.033 14.1 9.3 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DMP1 PF07263.11 KNZ77220.1 - 0.087 11.7 14.8 0.015 14.2 8.1 2.0 2 0 0 2 2 2 0 Dentin matrix protein 1 (DMP1) DUF4451 PF14616.6 KNZ77220.1 - 0.19 11.9 8.4 5.8 7.1 0.0 4.0 3 1 0 4 4 4 0 Domain of unknown function (DUF4451) Prok-RING_4 PF14447.6 KNZ77220.1 - 0.19 11.6 19.7 1.4 8.8 13.1 3.7 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 UBZ_FAAP20 PF15750.5 KNZ77220.1 - 0.39 10.7 3.9 1.9 8.5 0.2 3.3 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger Siva PF05458.12 KNZ77220.1 - 1 9.0 9.6 0.089 12.5 3.1 2.5 3 0 0 3 3 3 0 Cd27 binding protein (Siva) TRAF_BIRC3_bd PF16673.5 KNZ77220.1 - 2 8.3 5.9 1 9.2 0.1 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain zf-WRNIP1_ubi PF18279.1 KNZ77220.1 - 2.6 8.9 3.9 20 6.1 0.1 3.2 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Glyco_hydro_3_C PF01915.22 KNZ77221.1 - 4.6e-57 193.3 0.0 2.1e-56 191.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ77221.1 - 1.4e-40 139.7 0.0 2.5e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ77221.1 - 8.9e-23 80.2 0.0 2.7e-22 78.7 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KNZ77221.1 - 2.5e-07 30.6 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain SET PF00856.28 KNZ77222.1 - 1.4e-06 28.8 0.0 2.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 SET domain 7kD_DNA_binding PF02294.18 KNZ77223.1 - 0.02 14.9 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 7kD DNA-binding domain Sugar_tr PF00083.24 KNZ77224.1 - 2e-87 294.0 17.0 2.4e-87 293.7 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ77224.1 - 6.4e-35 120.7 46.6 4.7e-32 111.3 24.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KNZ77224.1 - 8.4e-12 44.4 18.9 3.1e-07 29.3 7.2 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 KNZ77224.1 - 3.2e-06 25.9 1.9 3.2e-06 25.9 1.9 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KNZ77224.1 - 0.033 12.6 3.2 0.039 12.3 0.3 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF1129 PF06570.11 KNZ77224.1 - 0.059 12.9 0.3 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Transposase_28 PF04195.12 KNZ77224.1 - 1.5 9.1 4.1 2.5 8.4 0.0 2.9 3 0 0 3 3 3 0 Putative gypsy type transposon Glyco_hydro_18 PF00704.28 KNZ77225.1 - 5.6e-64 216.8 1.2 7.4e-64 216.4 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M28 PF04389.17 KNZ77226.1 - 3.1e-28 98.8 0.0 5.7e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KNZ77226.1 - 1.1e-08 35.0 0.0 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 KNZ77226.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Vac14_Fig4_bd PF11916.8 KNZ77227.1 - 2.8e-79 265.0 8.7 5e-79 264.1 8.7 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KNZ77227.1 - 3e-41 139.9 0.1 3.1e-37 127.1 0.0 3.2 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KNZ77227.1 - 6.3e-08 32.2 0.1 0.039 14.2 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 KNZ77227.1 - 6.2e-06 26.4 3.2 0.12 12.5 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 KNZ77227.1 - 0.0002 21.8 0.1 4.1 8.0 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat DNA_repr_REX1B PF14966.6 KNZ77227.1 - 0.11 13.2 0.0 1.7 9.3 0.0 2.9 2 0 0 2 2 2 0 DNA repair REX1-B TIP120 PF08623.10 KNZ77227.1 - 0.12 12.2 0.0 3.5 7.4 0.0 2.8 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) ParcG PF10274.9 KNZ77227.1 - 0.12 12.5 0.2 10 6.2 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Y_phosphatase3 PF13350.6 KNZ77228.1 - 5e-62 209.9 0.0 5.6e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KNZ77228.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KNZ77228.1 - 0.047 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MCM PF00493.23 KNZ77229.1 - 4.6e-105 349.7 0.3 7.1e-105 349.1 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNZ77229.1 - 1.2e-38 131.8 0.0 2.3e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KNZ77229.1 - 1.2e-28 99.5 1.2 2.8e-28 98.3 1.2 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 KNZ77229.1 - 2.2e-26 92.5 0.2 6.8e-26 90.9 0.2 1.9 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KNZ77229.1 - 1.9e-24 85.9 1.6 1.9e-24 85.9 1.6 2.1 3 0 0 3 3 3 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KNZ77229.1 - 7.6e-08 32.0 0.0 5.9e-07 29.1 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KNZ77229.1 - 0.00058 19.7 0.1 0.0029 17.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNZ77229.1 - 0.0037 17.0 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KNZ77229.1 - 0.027 14.5 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) APH PF01636.23 KNZ77230.1 - 4.4e-06 26.8 0.6 1.8e-05 24.8 0.6 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ77230.1 - 9.8e-06 25.3 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ77230.1 - 0.0054 16.1 0.0 0.59 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 KNZ77230.1 - 0.025 14.2 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KNZ77230.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LNS2 PF08235.13 KNZ77232.1 - 3e-99 331.1 0.0 4.1e-99 330.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KNZ77232.1 - 1.2e-30 105.5 0.1 1.4e-27 95.6 0.0 2.8 2 1 0 2 2 2 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 KNZ77232.1 - 1.7e-06 28.1 0.0 3.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Acid_phosphat_B PF03767.14 KNZ77232.1 - 0.093 12.3 0.2 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Complex1_LYR PF05347.15 KNZ77233.1 - 5.2e-10 39.2 0.7 7.4e-10 38.7 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RRN3 PF05327.11 KNZ77234.1 - 6.9e-183 609.2 0.0 1.2e-101 341.0 0.0 2.0 1 1 1 2 2 2 2 RNA polymerase I specific transcription initiation factor RRN3 Ank_2 PF12796.7 KNZ77235.1 - 1.2e-14 54.6 2.0 9.4e-11 42.2 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ77235.1 - 9.1e-10 37.9 0.1 0.061 13.9 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KNZ77235.1 - 2.5e-08 34.3 0.1 0.00045 20.7 0.0 3.4 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ77235.1 - 4e-07 30.2 1.8 0.063 13.6 0.1 3.5 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KNZ77235.1 - 5.9e-06 26.5 3.6 0.1 13.1 0.4 4.6 3 2 0 3 3 3 1 Ankyrin repeat EFG_II PF14492.6 KNZ77235.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Elongation Factor G, domain II Rib_hydrolayse PF02267.17 KNZ77236.1 - 3.7e-06 26.5 0.0 6.1e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyl cyclase IU_nuc_hydro PF01156.19 KNZ77237.1 - 5.3e-72 243.0 0.0 6.2e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Peptidase_S28 PF05577.12 KNZ77238.1 - 6.6e-51 173.5 0.1 9.1e-38 130.2 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KNZ77238.1 - 0.011 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3939 PF13075.6 KNZ77238.1 - 0.22 11.6 0.0 10 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3939) Phage_integrase PF00589.22 KNZ77240.1 - 0.059 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phage integrase family zf-CCHC PF00098.23 KNZ77241.1 - 0.03 14.4 3.7 0.065 13.3 3.7 1.6 1 0 0 1 1 1 0 Zinc knuckle Chromo PF00385.24 KNZ77242.1 - 2.4e-16 59.3 0.0 3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.8 KNZ77242.1 - 0.023 14.6 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Mtf2_C PF14061.6 KNZ77242.1 - 0.035 14.3 0.1 0.046 13.9 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SAWADEE PF16719.5 KNZ77242.1 - 0.16 12.0 0.0 0.18 11.8 0.0 1.0 1 0 0 1 1 1 0 SAWADEE domain FMO-like PF00743.19 KNZ77243.1 - 2.5e-15 55.9 0.0 4.8e-15 55.0 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KNZ77243.1 - 1.8e-11 43.8 0.0 3.4e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNZ77243.1 - 6.7e-11 42.0 0.0 4e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ77243.1 - 6.9e-11 41.9 0.0 3.9e-08 32.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KNZ77243.1 - 2.1e-09 37.5 0.2 2.9e-08 33.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ77243.1 - 6.2e-05 22.7 0.0 0.28 10.7 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ77243.1 - 0.00012 22.2 0.5 0.28 11.2 0.0 3.8 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ77243.1 - 0.0014 19.2 0.5 1.9 9.1 0.3 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KNZ77243.1 - 0.022 14.1 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 KNZ77243.1 - 0.049 12.7 0.1 10 5.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KNZ77243.1 - 0.13 11.3 0.1 0.65 9.0 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KNZ77243.1 - 0.14 11.2 0.1 0.41 9.6 0.1 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KNZ77243.1 - 0.17 12.3 0.0 47 4.5 0.0 2.9 3 0 0 3 3 3 0 Putative NAD(P)-binding HI0933_like PF03486.14 KNZ77243.1 - 0.52 8.9 2.3 0.4 9.3 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Cellulase PF00150.18 KNZ77244.1 - 6.6e-44 150.4 0.0 9.3e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.9 KNZ77245.1 - 1.2e-21 76.9 0.0 5.1e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3328 PF11807.8 KNZ77245.1 - 0.061 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Pkinase PF00069.25 KNZ77246.1 - 1.9e-06 27.5 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ77246.1 - 0.00082 19.4 3.5 0.19 11.6 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KNZ77246.1 - 0.0055 16.0 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ77246.1 - 0.05 13.0 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Opi1 PF08618.10 KNZ77247.1 - 9.3e-119 397.4 10.9 5.1e-101 339.0 5.0 2.2 1 1 1 2 2 2 2 Transcription factor Opi1 DUF1199 PF06712.11 KNZ77247.1 - 0.016 15.2 0.1 0.067 13.2 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Perilipin PF03036.16 KNZ77247.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Perilipin family REF PF05755.12 KNZ77247.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Kinesin PF00225.23 KNZ77248.1 - 8.6e-98 327.3 0.1 3.7e-97 325.2 0.1 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ77248.1 - 8.3e-58 194.6 0.0 1.6e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding FH2 PF02181.23 KNZ77248.1 - 0.03 13.5 10.8 0.033 13.3 5.7 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain ADIP PF11559.8 KNZ77248.1 - 0.053 13.6 28.5 0.077 13.1 11.8 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding ThiS PF02597.20 KNZ77248.1 - 0.076 13.7 3.0 1.8 9.3 0.2 4.0 4 0 0 4 4 4 0 ThiS family Macoilin PF09726.9 KNZ77248.1 - 0.24 9.9 18.3 0.36 9.3 18.3 1.2 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 KNZ77248.1 - 0.67 8.8 25.4 1.3 7.9 16.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 KNZ77248.1 - 0.72 7.7 7.1 1.1 7.1 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD_2 PF12700.7 KNZ77248.1 - 0.75 8.5 4.4 1.2 7.8 4.4 1.4 1 0 0 1 1 1 0 HlyD family secretion protein zf-C4H2 PF10146.9 KNZ77248.1 - 0.95 9.7 8.3 2.7 8.2 8.3 1.9 1 0 0 1 1 1 0 Zinc finger-containing protein Atg14 PF10186.9 KNZ77248.1 - 2.9 6.9 20.9 14 4.6 20.8 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KNZ77248.1 - 3 7.9 18.7 3.1 7.9 7.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 KNZ77248.1 - 5.4 7.1 11.8 1.8 8.6 6.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 KNZ77248.1 - 6.2 7.5 16.6 14 6.4 0.0 4.9 3 1 1 4 4 4 0 Initiation control protein YabA p450 PF00067.22 KNZ77249.1 - 1.3e-65 222.0 0.0 1.4e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAP3 PF10236.9 KNZ77251.1 - 4.5e-59 200.1 0.0 6.9e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Exo_endo_phos PF03372.23 KNZ77251.1 - 2.5e-07 30.5 0.0 6.9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AAA_16 PF13191.6 KNZ77251.1 - 6.4e-07 29.9 0.0 1.6e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain zf-GRF PF06839.12 KNZ77251.1 - 1.6e-06 28.1 0.2 3.1e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 GRF zinc finger IstB_IS21 PF01695.17 KNZ77251.1 - 0.0033 17.2 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 KNZ77251.1 - 0.0061 16.5 0.0 0.014 15.4 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KNZ77251.1 - 0.018 14.6 0.0 0.057 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KNZ77251.1 - 0.053 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 KNZ77251.1 - 0.13 12.5 0.1 1 9.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF1381 PF07129.11 KNZ77251.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) RNA_helicase PF00910.22 KNZ77251.1 - 0.2 12.1 0.1 3.8 8.0 0.1 3.0 2 1 0 2 2 2 0 RNA helicase RsgA_GTPase PF03193.16 KNZ77251.1 - 0.2 11.5 0.2 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Amino_oxidase PF01593.24 KNZ77252.1 - 1.2e-65 222.6 0.0 1.6e-64 218.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ77252.1 - 1.6e-10 41.1 0.2 4.2e-10 39.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KNZ77252.1 - 2.2e-05 23.9 0.3 0.0003 20.2 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KNZ77252.1 - 5.4e-05 22.7 1.5 0.0015 18.0 2.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ77252.1 - 6.2e-05 22.4 0.3 0.018 14.3 0.1 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ77252.1 - 0.00015 22.2 0.4 0.031 14.8 0.4 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ77252.1 - 0.00041 20.0 0.6 0.003 17.2 0.7 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ77252.1 - 0.00056 19.1 0.3 0.00092 18.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KNZ77252.1 - 0.0024 17.2 0.1 0.0044 16.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KNZ77252.1 - 0.027 13.2 0.0 0.12 11.0 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 KNZ77252.1 - 0.076 12.3 0.2 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KNZ77252.1 - 0.17 12.0 0.1 0.29 11.2 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KNZ77252.1 - 0.39 9.7 1.2 0.49 9.4 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A UQ_con PF00179.26 KNZ77253.1 - 3.1e-17 62.6 0.1 3.5e-17 62.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KNZ77253.1 - 0.0042 17.4 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KNZ77253.1 - 0.044 13.7 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 UEV domain VHS PF00790.19 KNZ77254.1 - 3.1e-31 108.1 0.3 5.9e-31 107.2 0.3 1.5 1 0 0 1 1 1 1 VHS domain SH3_2 PF07653.17 KNZ77254.1 - 4.6e-14 51.9 0.2 8e-14 51.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ77254.1 - 5e-14 51.6 0.1 9.8e-14 50.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ77254.1 - 1.9e-13 50.0 0.2 3.6e-13 49.1 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KNZ77254.1 - 2.6e-10 40.4 1.1 6.3e-10 39.2 1.1 1.7 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KNZ77254.1 - 0.0026 17.5 2.2 0.0077 16.1 2.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF572 PF04502.13 KNZ77254.1 - 1.9 8.1 12.0 0.51 9.9 4.7 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF572) IRF-3 PF10401.9 KNZ77256.1 - 0.039 13.7 0.1 0.039 13.7 0.1 1.1 1 0 0 1 1 1 0 Interferon-regulatory factor 3 Amino_oxidase PF01593.24 KNZ77258.1 - 1.6e-66 225.5 0.0 4.2e-64 217.5 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ77258.1 - 9.3e-12 45.0 0.3 2.2e-11 43.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KNZ77258.1 - 0.00025 20.2 0.4 0.00038 19.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 KNZ77258.1 - 0.00048 19.5 0.9 0.0008 18.8 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KNZ77258.1 - 0.00082 19.1 0.9 0.0023 17.6 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KNZ77258.1 - 0.00085 18.8 0.3 0.0014 18.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KNZ77258.1 - 0.0033 16.8 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KNZ77258.1 - 0.0052 16.1 0.7 0.012 14.9 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ77258.1 - 0.039 14.5 0.4 0.1 13.2 0.4 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ77258.1 - 0.075 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ77258.1 - 0.077 11.7 0.1 0.15 10.8 0.1 1.4 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KNZ77258.1 - 0.21 10.6 0.2 0.33 10.0 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Acetyltransf_3 PF13302.7 KNZ77259.1 - 3.3e-11 44.0 0.0 4.3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ77259.1 - 9.5e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ilar_coat PF01787.16 KNZ77259.1 - 0.086 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Ilarvirus coat protein zf-C2H2_jaz PF12171.8 KNZ77261.1 - 1.3e-10 41.3 2.1 2.2e-10 40.6 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNZ77261.1 - 0.0099 16.2 0.3 0.016 15.6 0.3 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KNZ77261.1 - 0.051 14.0 1.4 0.091 13.2 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KNZ77261.1 - 0.12 13.3 0.4 0.12 13.3 0.4 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger RNase_H PF00075.24 KNZ77262.1 - 1.8e-08 34.7 0.0 3.4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 RNase H DUF1043 PF06295.12 KNZ77262.1 - 0.02 14.9 0.3 0.049 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) zf-RVT PF13966.6 KNZ77263.1 - 0.0024 18.5 0.9 0.0025 18.5 0.9 1.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zinc_ribbon_9 PF14369.6 KNZ77263.1 - 0.11 12.8 4.4 0.46 10.8 2.0 2.3 1 1 1 2 2 2 0 zinc-ribbon gag-asp_proteas PF13975.6 KNZ77266.1 - 7.2e-06 26.5 0.0 1.1e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ77266.1 - 2.7e-05 24.7 0.0 5.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ77266.1 - 0.007 16.2 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Retrotran_gag_2 PF14223.6 KNZ77267.1 - 6.4e-08 32.4 1.1 1.6e-07 31.1 1.1 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type eIF3g PF12353.8 KNZ77267.1 - 0.0085 16.5 0.6 0.018 15.5 0.6 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Acetyltransf_3 PF13302.7 KNZ77268.1 - 6.9e-10 39.7 0.0 9.2e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ77268.1 - 0.00095 19.4 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-C2H2_jaz PF12171.8 KNZ77269.1 - 9.9e-11 41.6 2.2 1.6e-10 40.9 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNZ77269.1 - 0.0047 17.2 0.3 0.0073 16.6 0.3 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KNZ77269.1 - 0.084 13.3 1.4 0.15 12.5 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KNZ77269.1 - 0.11 13.4 0.3 0.11 13.4 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Cellulase PF00150.18 KNZ77270.1 - 6e-15 55.4 0.0 8.8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_31 PF13847.6 KNZ77271.1 - 3.6e-24 85.3 0.0 6.2e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ77271.1 - 5.3e-20 71.9 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ77271.1 - 1.5e-18 67.2 0.0 4e-18 65.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ77271.1 - 1.6e-13 50.6 0.0 2.9e-13 49.7 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KNZ77271.1 - 8e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ77271.1 - 2.3e-09 37.3 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.20 KNZ77271.1 - 2.6e-09 37.5 0.0 1.6e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain MTS PF05175.14 KNZ77271.1 - 5e-06 26.2 0.0 9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KNZ77271.1 - 2.6e-05 23.7 0.1 5.1e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KNZ77271.1 - 0.00012 22.0 0.0 0.0005 19.9 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KNZ77271.1 - 0.00058 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_2 PF00891.18 KNZ77271.1 - 0.0064 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 KNZ77271.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Macin PF14865.6 KNZ77271.1 - 0.049 14.2 0.2 0.12 12.9 0.2 1.6 1 0 0 1 1 1 0 Macin Methyltransf_24 PF13578.6 KNZ77271.1 - 0.091 13.8 0.0 0.23 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KNZ77271.1 - 0.15 11.6 0.1 0.37 10.2 0.1 1.8 1 1 0 1 1 1 0 Putative methyltransferase HMG_box PF00505.19 KNZ77272.1 - 5.2e-13 49.2 0.1 9.2e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ77272.1 - 0.011 16.3 0.5 0.027 15.1 0.1 1.9 1 1 1 2 2 2 0 HMG-box domain Sugar_tr PF00083.24 KNZ77274.1 - 1.2e-17 63.9 22.5 8.1e-14 51.3 4.6 3.2 1 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 KNZ77274.1 - 4.9e-15 55.3 48.4 1.1e-07 31.1 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Putative_PNPOx PF01243.20 KNZ77275.1 - 1.7e-05 24.9 0.0 0.0095 16.1 0.0 3.9 3 2 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 KNZ77275.1 - 0.0031 18.2 0.0 0.0071 17.0 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Pkinase PF00069.25 KNZ77276.1 - 1e-48 166.0 0.0 1.3e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77276.1 - 1.7e-23 83.3 0.0 2.4e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ77276.1 - 0.0036 16.6 0.0 0.0085 15.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Cutinase PF01083.22 KNZ77277.1 - 5.9e-45 153.4 0.1 6.7e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KNZ77277.1 - 0.00027 20.6 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 KNZ77277.1 - 0.0027 17.3 0.6 0.0059 16.2 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) VirJ PF06057.11 KNZ77277.1 - 0.0083 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.20 KNZ77277.1 - 0.0088 15.7 0.0 0.0092 15.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KNZ77277.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) LIP PF03583.14 KNZ77277.1 - 0.11 11.7 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Secretory lipase DLH PF01738.18 KNZ77284.1 - 2.6e-20 72.9 0.0 3.9e-20 72.3 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KNZ77284.1 - 0.061 12.8 0.0 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.14 KNZ77285.1 - 1e-54 185.6 0.7 1.3e-54 185.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KNZ77285.1 - 2.4e-12 46.6 12.5 2.4e-12 46.6 12.5 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 KNZ77285.1 - 0.7 7.9 6.3 0.74 7.8 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HMG_box PF00505.19 KNZ77286.1 - 3.8e-11 43.2 1.1 1.7e-10 41.2 1.1 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ77286.1 - 0.054 14.1 0.1 0.1 13.2 0.1 1.5 1 1 0 1 1 1 0 HMG-box domain DUF4449 PF14613.6 KNZ77287.1 - 1.9e-32 112.6 0.8 5.1e-32 111.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Peptidase_C47 PF05543.13 KNZ77288.1 - 0.18 11.4 2.2 1.2 8.7 0.0 2.1 1 1 1 2 2 2 0 Staphopain peptidase C47 TMEM154 PF15102.6 KNZ77289.1 - 0.00029 20.7 1.0 0.00049 20.0 1.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family MGC-24 PF05283.11 KNZ77289.1 - 0.00033 21.1 2.6 0.00033 21.1 2.6 1.5 2 0 0 2 2 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin RIFIN PF02009.16 KNZ77289.1 - 0.00089 19.2 0.4 0.0013 18.7 0.1 1.4 2 0 0 2 2 2 1 Rifin BatD PF13584.6 KNZ77289.1 - 0.0036 16.2 0.5 0.0078 15.1 0.1 1.6 2 0 0 2 2 2 1 Oxygen tolerance Mid2 PF04478.12 KNZ77289.1 - 0.033 14.0 1.4 0.056 13.3 1.4 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM51 PF15345.6 KNZ77289.1 - 0.045 13.6 0.5 0.064 13.1 0.2 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 DUF5305 PF17231.2 KNZ77289.1 - 0.046 13.1 0.4 0.075 12.4 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) EphA2_TM PF14575.6 KNZ77289.1 - 0.063 14.2 0.0 0.17 12.8 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain L6_membrane PF05805.12 KNZ77289.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 L6 membrane protein Syndecan PF01034.20 KNZ77289.1 - 0.076 12.9 0.9 0.15 12.0 0.9 1.4 1 0 0 1 1 1 0 Syndecan domain FAM163 PF15069.6 KNZ77289.1 - 0.1 13.1 0.1 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 FAM163 family Adeno_E3_CR2 PF02439.15 KNZ77289.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2207 PF09972.9 KNZ77289.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SKG6 PF08693.10 KNZ77289.1 - 0.13 11.6 8.1 0.36 10.3 8.1 1.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 KNZ77289.1 - 0.16 10.8 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 KNZ77289.1 - 0.35 10.4 0.9 0.52 9.8 0.9 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame MFS_1 PF07690.16 KNZ77290.1 - 9.3e-18 64.3 54.7 1.7e-13 50.2 33.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily S1FA PF04689.13 KNZ77290.1 - 1.4 9.1 5.2 6.7 6.9 0.0 3.6 3 0 0 3 3 3 0 DNA binding protein S1FA Methyltransf_2 PF00891.18 KNZ77291.1 - 8.6e-28 97.1 0.0 6.9e-27 94.1 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_31 PF13847.6 KNZ77291.1 - 9.1e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ77291.1 - 2.3e-05 25.0 0.0 5.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ77291.1 - 5.9e-05 23.7 0.0 0.00018 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ77291.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KNZ77291.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KNZ77291.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SKN1 PF03935.15 KNZ77292.1 - 7.7e-172 572.2 6.4 1.2e-105 353.8 5.4 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Lyase_1 PF00206.20 KNZ77293.1 - 7.3e-20 71.6 0.0 1.7e-19 70.3 0.0 1.6 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 KNZ77293.1 - 9.3e-19 67.8 0.0 2.8e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus HEM4 PF02602.15 KNZ77294.1 - 1.5e-31 109.6 0.0 1.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Mito_carr PF00153.27 KNZ77295.1 - 3.5e-62 206.3 7.5 2.9e-22 78.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4352 PF11611.8 KNZ77295.1 - 0.081 13.2 0.0 0.31 11.3 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4352) DUF3185 PF11381.8 KNZ77295.1 - 0.1 12.6 2.3 17 5.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF2635 PF10948.8 KNZ77296.1 - 0.012 15.3 0.3 1.6 8.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2635) Amidohydro_2 PF04909.14 KNZ77297.1 - 3.9e-25 89.2 0.0 6.1e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase PseudoU_synth_2 PF00849.22 KNZ77297.1 - 5e-19 68.9 0.0 7.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Rtt106 PF08512.12 KNZ77298.1 - 2.4e-12 47.1 0.0 8.9e-12 45.3 0.0 2.0 2 1 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KNZ77298.1 - 0.0016 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_hydro_10 PF00331.20 KNZ77299.1 - 2.5e-98 329.2 0.0 2.8e-98 329.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 SWIB PF02201.18 KNZ77300.1 - 2.4e-21 75.4 0.0 5.2e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain BAR PF03114.18 KNZ77301.1 - 1e-35 123.5 9.0 1.6e-35 122.9 9.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KNZ77301.1 - 2.7e-10 39.7 2.0 6.7e-10 38.4 0.3 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KNZ77301.1 - 7.3e-09 35.4 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 KNZ77301.1 - 1.2e-08 35.0 6.1 4e-08 33.2 6.3 1.6 2 0 0 2 2 2 1 BAR domain of APPL family SH3_2 PF07653.17 KNZ77301.1 - 5.6e-08 32.4 0.0 1.4e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF883 PF05957.13 KNZ77301.1 - 0.022 15.3 3.8 0.054 14.1 3.8 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MscS_TM PF12794.7 KNZ77301.1 - 1.2 7.9 5.2 1.8 7.4 5.2 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 APG6_N PF17675.1 KNZ77301.1 - 1.8 9.1 14.2 3.7 8.1 14.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 KNZ77301.1 - 3.4 6.2 5.6 5.2 5.6 5.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ras PF00071.22 KNZ77302.1 - 3.6e-47 160.0 1.3 4.1e-47 159.8 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ77302.1 - 4.8e-16 59.1 0.0 7.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ77302.1 - 4.9e-08 32.6 0.0 6.2e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ77302.1 - 3e-06 27.3 0.1 1.1e-05 25.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ77302.1 - 1.2e-05 25.3 0.3 0.044 13.7 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KNZ77302.1 - 2.8e-05 23.7 0.3 0.00064 19.3 0.3 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 KNZ77302.1 - 7.6e-05 22.3 0.8 0.0016 18.0 0.9 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 KNZ77302.1 - 0.00048 20.2 0.2 0.0017 18.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KNZ77302.1 - 0.00064 19.8 0.1 0.0014 18.7 0.1 1.7 1 1 0 1 1 1 1 Dynamin family ATPase_2 PF01637.18 KNZ77302.1 - 0.0012 18.8 0.8 0.0056 16.6 0.8 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KNZ77302.1 - 0.024 14.4 0.6 0.55 10.0 0.2 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TniB PF05621.11 KNZ77302.1 - 0.054 12.9 0.2 0.2 11.0 0.0 1.9 2 1 1 3 3 3 0 Bacterial TniB protein AAA_16 PF13191.6 KNZ77302.1 - 0.078 13.4 0.0 0.09 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 KNZ77302.1 - 0.11 11.6 1.2 0.46 9.6 1.2 2.2 1 1 0 1 1 1 0 G-protein alpha subunit WD40 PF00400.32 KNZ77303.1 - 8.1e-08 32.8 7.3 0.0039 18.0 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 KNZ77303.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 KNZ77304.1 - 1.9e-71 240.5 0.0 2.7e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77304.1 - 6.4e-38 130.5 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ77304.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 KNZ77304.1 - 7.6e-05 22.4 0.1 0.00028 20.6 0.0 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 Haspin_kinase PF12330.8 KNZ77304.1 - 0.0065 15.5 0.3 0.012 14.6 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 KNZ77304.1 - 0.017 14.8 0.1 0.039 13.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KNZ77304.1 - 0.98 9.3 5.5 0.13 12.2 0.4 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family KA1 PF02149.19 KNZ77305.1 - 2.2e-05 24.2 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 SNase PF00565.17 KNZ77306.1 - 1.7e-08 34.9 0.0 2.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MetallophosC PF16370.5 KNZ77308.1 - 0.019 15.2 0.3 0.03 14.6 0.3 1.2 1 0 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Amnionless PF14828.6 KNZ77308.1 - 0.028 13.3 0.2 0.053 12.3 0.2 1.5 1 1 0 1 1 1 0 Amnionless Mid2 PF04478.12 KNZ77308.1 - 0.051 13.4 0.2 0.051 13.4 0.2 3.2 3 1 1 4 4 4 0 Mid2 like cell wall stress sensor rve PF00665.26 KNZ77309.1 - 6.7e-12 45.6 0.2 8.8e-11 42.0 0.0 2.5 2 1 1 3 3 3 1 Integrase core domain gag_pre-integrs PF13976.6 KNZ77309.1 - 3.2e-05 23.7 0.0 9.3e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain AOX PF01786.17 KNZ77310.1 - 1.7e-15 57.2 0.0 2.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase RNA_pol PF00940.19 KNZ77311.1 - 2.6e-180 599.7 0.1 3.3e-180 599.3 0.1 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KNZ77311.1 - 1.9e-93 313.5 0.2 3.3e-93 312.8 0.2 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Histone PF00125.24 KNZ77312.1 - 2.2e-17 63.6 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KNZ77312.1 - 3.6e-10 39.4 0.1 6.2e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KNZ77312.1 - 0.0092 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Integrase_H2C2 PF17921.1 KNZ77313.1 - 2.4e-07 30.7 1.7 4.4e-07 29.9 1.7 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KNZ77313.1 - 0.0045 17.2 0.2 0.0086 16.3 0.2 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Prefoldin_2 PF01920.20 KNZ77314.1 - 0.021 14.7 0.1 0.027 14.4 0.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF1661 PF07877.11 KNZ77314.1 - 0.024 14.3 0.9 0.039 13.6 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) TFIID_20kDa PF03847.13 KNZ77314.1 - 0.087 13.3 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_hydro_6 PF01341.17 KNZ77315.1 - 5.2e-108 361.4 1.7 6.4e-108 361.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KNZ77315.1 - 7.8e-13 48.1 4.1 2.2e-12 46.7 4.1 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain ATP_sub_h PF10775.9 KNZ77316.1 - 2.4e-26 91.5 0.9 3.9e-26 90.8 0.9 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h IATP PF04568.12 KNZ77317.1 - 9.2e-07 29.2 5.5 1.1e-06 29.0 5.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.15 KNZ77317.1 - 0.26 11.1 4.0 0.36 10.6 4.0 1.3 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.7 KNZ77318.1 - 0.00026 20.8 0.2 0.00069 19.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like CBM_19 PF03427.13 KNZ77318.1 - 0.13 12.3 0.3 0.26 11.3 0.3 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DUF1289 PF06945.13 KNZ77319.1 - 0.058 13.2 0.1 0.082 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) p450 PF00067.22 KNZ77320.1 - 7.3e-44 150.3 0.1 8.4e-44 150.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.12 KNZ77322.1 - 1.7e-07 31.1 14.1 1.7e-07 31.1 14.1 2.0 1 1 0 2 2 2 1 SUR7/PalI family DuoxA PF10204.9 KNZ77322.1 - 0.0057 15.7 3.6 0.0057 15.7 3.6 1.4 2 0 0 2 2 2 1 Dual oxidase maturation factor Trp_oprn_chp PF09534.10 KNZ77322.1 - 0.6 9.9 7.5 1.1 9.1 7.5 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Asp_protease_2 PF13650.6 KNZ77323.1 - 0.086 13.5 0.0 0.13 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease Glyco_hydro_16 PF00722.21 KNZ77325.1 - 2.7e-13 49.8 1.7 5e-12 45.6 1.7 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Adaptin_N PF01602.20 KNZ77326.1 - 8.8e-143 476.6 5.5 1.1e-142 476.3 5.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KNZ77326.1 - 1.3e-61 207.4 4.2 2e-60 203.5 1.0 2.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ77326.1 - 6.9e-18 64.8 3.2 1.8e-06 28.2 0.0 6.1 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KNZ77326.1 - 2.7e-09 36.5 6.9 0.00014 21.8 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KNZ77326.1 - 9.8e-05 22.8 2.2 1.9 9.1 0.1 5.9 5 1 1 6 6 6 1 HEAT-like repeat RTP1_C1 PF10363.9 KNZ77326.1 - 0.00051 20.2 1.9 0.7 10.1 0.0 4.3 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KNZ77326.1 - 0.00053 19.6 0.1 0.38 10.3 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.23 KNZ77326.1 - 0.0088 16.1 5.1 13 6.0 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 KNZ77326.1 - 0.039 13.9 1.7 0.39 10.6 0.1 3.0 1 1 2 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Uso1_p115_head PF04869.14 KNZ77326.1 - 0.041 13.0 0.1 0.099 11.8 0.1 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region MMS19_C PF12460.8 KNZ77326.1 - 0.076 12.1 1.4 14 4.7 0.0 3.2 3 1 0 4 4 4 0 RNAPII transcription regulator C-terminal SET PF00856.28 KNZ77328.1 - 2.2e-09 37.9 0.2 6.5e-09 36.4 0.2 1.8 1 1 0 1 1 1 1 SET domain SPX PF03105.19 KNZ77328.1 - 0.43 10.5 3.0 0.66 9.8 3.0 1.2 1 0 0 1 1 1 0 SPX domain TMEM171 PF15471.6 KNZ77330.1 - 0.093 11.7 3.2 0.076 12.0 1.9 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF5383 PF17355.2 KNZ77330.1 - 0.21 12.0 0.0 0.28 11.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) RrnaAD PF00398.20 KNZ77331.1 - 7.3e-58 195.7 0.0 9.8e-58 195.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KNZ77331.1 - 2.8e-07 31.1 0.0 6.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KNZ77331.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KNZ77331.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ77331.1 - 0.00017 22.2 0.0 0.00035 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ77331.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 KNZ77331.1 - 0.0026 17.1 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KNZ77331.1 - 0.0039 16.5 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KNZ77331.1 - 0.0052 17.5 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 KNZ77331.1 - 0.052 13.1 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 Nodulation protein S (NodS) Met_10 PF02475.16 KNZ77331.1 - 0.054 13.2 0.4 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_2 PF00891.18 KNZ77331.1 - 0.056 12.7 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_28 PF02636.17 KNZ77331.1 - 0.084 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.12 KNZ77331.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase SUI1 PF01253.22 KNZ77332.1 - 5e-19 68.6 0.0 1.5e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 KNZ77332.1 - 4.3e-13 49.7 0.0 4.4e-12 46.5 0.0 2.6 3 0 0 3 3 3 1 Pre-PUA-like domain PUA PF01472.20 KNZ77332.1 - 0.0092 15.9 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 PUA domain SWIB PF02201.18 KNZ77332.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 SWIB/MDM2 domain NUP PF06516.11 KNZ77333.1 - 4.8e-93 311.8 0.1 6.2e-93 311.4 0.1 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) PNP_UDP_1 PF01048.20 KNZ77333.1 - 5.9e-36 123.9 0.0 1.1e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NUP PF06516.11 KNZ77334.1 - 3e-93 312.5 0.2 3.4e-93 312.3 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) SurE PF01975.17 KNZ77335.1 - 1.5e-35 122.7 0.9 2.3e-35 122.1 0.9 1.3 1 0 0 1 1 1 1 Survival protein SurE DDHD PF02862.17 KNZ77336.1 - 0.064 13.4 14.9 0.069 13.3 5.7 2.4 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.16 KNZ77336.1 - 0.95 9.5 8.7 0.78 9.8 4.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 KNZ77336.1 - 1.3 8.1 10.0 0.054 12.7 3.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Kelch_4 PF13418.6 KNZ77337.1 - 1e-35 121.5 15.3 9.3e-07 28.8 0.3 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KNZ77337.1 - 1.3e-35 120.7 6.1 3.7e-08 32.8 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 KNZ77337.1 - 8.5e-33 111.8 3.6 4.7e-08 32.9 0.0 5.7 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KNZ77337.1 - 7.8e-32 108.9 10.3 1.8e-06 28.1 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ77337.1 - 3.1e-31 106.6 9.8 1.5e-06 28.2 0.1 6.2 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KNZ77337.1 - 7.4e-27 92.3 12.0 3.4e-05 23.6 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Cu_bind_like PF02298.17 KNZ77338.1 - 0.043 13.8 0.0 0.17 11.9 0.0 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Crust_neurohorm PF01147.17 KNZ77339.1 - 0.087 12.7 0.2 5.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family PIF1 PF05970.14 KNZ77340.1 - 3.3e-108 362.1 0.0 4e-108 361.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77340.1 - 9.6e-08 32.0 0.0 1.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KNZ77340.1 - 2.7e-06 25.6 0.0 3.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ77340.1 - 0.00076 19.3 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KNZ77340.1 - 0.0019 18.0 0.3 0.26 11.0 0.2 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ77340.1 - 0.015 15.3 0.0 0.045 13.8 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit 4HPAD_g_N PF18671.1 KNZ77340.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal AAA_16 PF13191.6 KNZ77340.1 - 0.044 14.2 0.0 0.075 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 KNZ77342.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ77342.1 - 0.039 14.4 0.1 4.7 7.7 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ77342.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KNZ77342.1 - 0.15 12.2 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Got1 PF04178.12 KNZ77343.1 - 7.1e-33 113.4 10.3 9.4e-33 113.0 10.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family AgrB PF04647.15 KNZ77343.1 - 0.038 13.3 4.1 0.052 12.8 4.1 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF2070 PF09843.9 KNZ77343.1 - 0.066 11.5 2.7 0.076 11.3 2.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MNHE PF01899.16 KNZ77343.1 - 0.74 9.6 6.4 0.21 11.4 1.4 1.9 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit Nup192 PF11894.8 KNZ77345.1 - 6.6e-212 706.5 0.0 9e-212 706.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 aGPT-Pplase1 PF18723.1 KNZ77346.1 - 7.5e-97 324.1 0.0 1.2e-95 320.2 0.0 1.9 2 0 0 2 2 2 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Chromo PF00385.24 KNZ77346.1 - 1.7e-10 40.6 0.1 3.9e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MT-A70 PF05063.14 KNZ77347.1 - 2.1e-39 135.2 0.0 3.8e-39 134.4 0.0 1.4 1 1 0 1 1 1 1 MT-A70 N6-adenineMlase PF10237.9 KNZ77347.1 - 0.19 11.5 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Noc2 PF03715.13 KNZ77348.1 - 9.8e-114 379.6 0.4 7.5e-113 376.7 0.1 2.2 2 0 0 2 2 2 1 Noc2p family Ribosomal_L28 PF00830.19 KNZ77349.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L28 family HSP70 PF00012.20 KNZ77350.1 - 0.0041 15.4 0.0 0.013 13.7 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein BcrAD_BadFG PF01869.20 KNZ77350.1 - 0.016 14.7 0.1 0.033 13.7 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.13 KNZ77350.1 - 0.047 12.5 0.0 0.11 11.3 0.1 1.5 2 0 0 2 2 2 0 MreB/Mbl protein ALO PF04030.14 KNZ77351.1 - 4.4e-79 266.0 3.4 6e-79 265.5 3.4 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KNZ77351.1 - 3.3e-18 65.8 1.3 5.6e-17 61.8 1.3 2.3 1 1 0 1 1 1 1 FAD binding domain DDE_Tnp_1_assoc PF13808.6 KNZ77351.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 DDE_Tnp_1-associated UQ_con PF00179.26 KNZ77352.1 - 3.3e-45 153.2 0.0 3.7e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNA_pol_Rpb2_6 PF00562.28 KNZ77353.1 - 4.2e-125 417.9 0.1 6.3e-125 417.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.14 KNZ77353.1 - 2.2e-29 102.4 0.0 7.1e-29 100.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 KNZ77353.1 - 9.3e-28 96.5 0.3 2.8e-27 95.0 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.15 KNZ77353.1 - 2.7e-26 92.3 0.0 4.7e-20 72.0 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 KNZ77353.1 - 1.6e-24 85.9 1.7 4.1e-24 84.7 1.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KNZ77353.1 - 6.5e-20 71.1 0.0 1.4e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KNZ77353.1 - 8.5e-11 42.3 1.0 2.7e-10 40.6 1.0 1.9 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 UQ_con PF00179.26 KNZ77354.1 - 5.9e-41 139.4 0.0 6.9e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNZ77354.1 - 0.0043 16.7 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B SNF2_N PF00176.23 KNZ77355.1 - 6.1e-42 143.6 0.0 9.8e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ77355.1 - 1.2e-20 73.9 0.0 2.6e-17 63.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain VIGSSK PF14773.6 KNZ77355.1 - 1.8e-07 31.1 0.1 4.9e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ERCC3_RAD25_C PF16203.5 KNZ77355.1 - 0.00074 18.8 0.0 0.0018 17.5 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SEC-C PF02810.15 KNZ77355.1 - 0.43 10.5 7.4 0.72 9.8 7.4 1.4 1 0 0 1 1 1 0 SEC-C motif Peptidase_C65 PF10275.9 KNZ77356.1 - 8.2e-56 189.2 0.0 1.1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 KNZ77356.1 - 0.038 14.5 0.0 4.1 7.9 0.0 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease RuBisCO_small PF00101.20 KNZ77357.1 - 0.046 13.7 0.0 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain DDE_Tnp_IS240 PF13610.6 KNZ77357.1 - 0.18 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 DDE domain Oxysterol_BP PF01237.18 KNZ77359.1 - 2e-57 194.7 0.0 2.9e-48 164.6 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein HMG_box PF00505.19 KNZ77360.1 - 4.3e-19 68.7 1.5 5.8e-19 68.3 1.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ77360.1 - 4.2e-13 49.7 1.3 5.6e-13 49.3 1.3 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.6 KNZ77360.1 - 0.0062 16.5 0.2 0.0073 16.2 0.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.12 KNZ77360.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain RTT107_BRCT_5 PF16770.5 KNZ77361.1 - 0.0025 17.7 0.1 3.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain GUB_WAK_bind PF13947.6 KNZ77361.1 - 0.063 14.0 0.0 27 5.6 0.0 2.6 2 0 0 2 2 2 0 Wall-associated receptor kinase galacturonan-binding Plug_translocon PF10559.9 KNZ77361.1 - 3.6 7.5 10.5 86 3.1 0.0 5.9 8 0 0 8 8 8 0 Plug domain of Sec61p Aldo_ket_red PF00248.21 KNZ77364.1 - 1.7e-43 148.9 0.0 1.8e-41 142.2 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Nnf1 PF03980.14 KNZ77365.1 - 1.3e-09 38.4 4.0 2e-09 37.8 2.4 1.9 2 0 0 2 2 2 1 Nnf1 Prominin PF05478.11 KNZ77365.1 - 0.0035 15.4 0.8 0.0042 15.1 0.8 1.1 1 0 0 1 1 1 1 Prominin SOGA PF11365.8 KNZ77365.1 - 0.056 14.6 0.8 0.056 14.6 0.8 1.8 2 0 0 2 2 2 0 Protein SOGA P4Ha_N PF08336.11 KNZ77365.1 - 0.08 13.0 2.3 0.22 11.6 0.3 2.1 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TraF_2 PF13729.6 KNZ77365.1 - 0.16 11.3 3.1 1.9 7.8 3.1 2.0 1 1 0 1 1 1 0 F plasmid transfer operon, TraF, protein TSC22 PF01166.18 KNZ77365.1 - 0.41 11.0 2.9 19 5.6 0.9 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.15 KNZ77365.1 - 0.58 10.0 6.5 0.48 10.2 2.4 2.2 2 0 0 2 2 2 0 Septum formation initiator EntA_Immun PF08951.10 KNZ77365.1 - 0.98 9.8 6.4 0.71 10.3 0.3 2.6 3 0 0 3 3 3 0 Enterocin A Immunity DUF244 PF03112.14 KNZ77365.1 - 3.2 7.6 7.1 3.3 7.5 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF PQ-loop PF04193.14 KNZ77366.1 - 0.0029 17.3 0.3 0.012 15.4 0.3 2.0 1 0 0 1 1 1 1 PQ loop repeat zf-RING_11 PF17123.5 KNZ77366.1 - 0.017 14.9 0.9 4.4 7.1 0.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger Methyltransf_16 PF10294.9 KNZ77367.1 - 3.9e-22 78.8 0.0 6.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KNZ77367.1 - 0.0002 21.2 0.0 0.00052 19.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KNZ77367.1 - 0.0019 18.0 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 KNZ77367.1 - 0.0044 16.8 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 KNZ77367.1 - 0.018 15.8 0.1 0.053 14.2 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ77367.1 - 0.08 13.7 0.1 0.25 12.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KNZ77367.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Rhomboid PF01694.22 KNZ77368.1 - 2.1e-17 63.5 14.1 2.7e-17 63.2 11.9 2.3 2 1 0 2 2 2 1 Rhomboid family Methyltransf_16 PF10294.9 KNZ77369.1 - 4e-26 91.8 0.1 5.8e-26 91.3 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase DEAD PF00270.29 KNZ77370.1 - 1.1e-46 158.9 0.0 2.1e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ77370.1 - 4.4e-24 85.0 0.3 4.4e-23 81.7 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KNZ77370.1 - 3.1e-20 72.1 0.0 7.8e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KNZ77370.1 - 1.9e-05 24.7 0.0 5.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KNZ77370.1 - 5.9 6.1 10.5 5.2 6.3 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit M20_dimer PF07687.14 KNZ77371.1 - 4.8e-10 39.3 0.0 1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Arginosuc_synth PF00764.19 KNZ77372.1 - 3.8e-154 513.7 0.0 4.6e-154 513.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KNZ77372.1 - 0.00054 19.5 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KNZ77372.1 - 0.012 14.4 0.0 0.021 13.6 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase zf-C3HC4_2 PF13923.6 KNZ77373.1 - 5.2e-08 32.6 3.1 5.2e-08 32.6 3.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ77373.1 - 2.5e-06 27.3 5.8 6.5e-06 25.9 5.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ77373.1 - 2.5e-06 27.4 5.0 2.5e-06 27.4 5.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KNZ77373.1 - 1.2e-05 25.0 11.7 0.0002 21.1 11.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ77373.1 - 2.9e-05 23.9 7.2 5.4e-05 23.1 7.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 KNZ77373.1 - 4.7e-05 23.2 0.2 0.00011 22.0 0.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 KNZ77373.1 - 7e-05 23.1 15.5 0.0013 19.1 15.5 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 KNZ77373.1 - 0.00021 21.4 4.7 0.00021 21.4 4.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KNZ77373.1 - 0.00025 20.8 8.4 0.00042 20.1 2.5 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KNZ77373.1 - 0.015 15.4 0.8 0.034 14.3 0.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 YlbD_coat PF14071.6 KNZ77373.1 - 0.025 14.9 4.4 0.048 13.9 4.4 1.4 1 0 0 1 1 1 0 Putative coat protein MMtag PF10159.9 KNZ77373.1 - 0.076 13.3 1.7 0.22 11.9 1.7 1.8 1 0 0 1 1 1 0 Multiple myeloma tumor-associated zf-rbx1 PF12678.7 KNZ77373.1 - 0.2 12.0 10.4 2.1 8.7 10.4 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain ThiI PF02568.14 KNZ77373.1 - 0.21 11.2 1.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) TMPIT PF07851.13 KNZ77373.1 - 0.33 10.1 7.0 0.51 9.5 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Zn_ribbon_17 PF17120.5 KNZ77373.1 - 0.5 10.0 7.2 0.11 12.1 1.3 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Nucleopor_Nup85 PF07575.13 KNZ77374.1 - 1.6e-55 188.8 0.0 4e-55 187.5 0.0 1.6 1 1 0 1 1 1 1 Nup85 Nucleoporin RhoGAP PF00620.27 KNZ77375.1 - 9.3e-47 158.7 0.0 2.4e-46 157.3 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KNZ77375.1 - 5.8e-09 36.1 2.8 1.6e-08 34.7 0.1 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1664 PF07889.12 KNZ77375.1 - 0.00031 20.8 0.8 0.027 14.5 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) PCRF PF03462.18 KNZ77375.1 - 0.005 16.7 3.4 0.013 15.4 3.4 1.6 1 0 0 1 1 1 1 PCRF domain Golgin_A5 PF09787.9 KNZ77375.1 - 0.011 15.2 8.3 0.02 14.4 8.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5344 PF17279.2 KNZ77375.1 - 0.046 14.3 4.1 1.2 9.8 1.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5344) RFC1 PF08519.12 KNZ77375.1 - 0.068 13.3 1.4 0.87 9.7 0.0 2.6 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain Exonuc_VII_L PF02601.15 KNZ77375.1 - 0.094 12.3 4.6 0.2 11.2 4.6 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mod_r PF07200.13 KNZ77375.1 - 0.11 12.5 9.5 0.17 11.9 6.2 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 KNZ77375.1 - 0.19 10.3 2.8 0.32 9.5 2.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A SKA2 PF16740.5 KNZ77375.1 - 0.25 11.1 7.9 0.19 11.5 5.7 1.9 2 0 0 2 2 1 0 Spindle and kinetochore-associated protein 2 TBCA PF02970.16 KNZ77375.1 - 0.5 10.7 7.1 1.6 9.1 7.1 1.9 1 0 0 1 1 1 0 Tubulin binding cofactor A CENP-F_leu_zip PF10473.9 KNZ77375.1 - 0.97 9.5 15.1 0.76 9.8 13.1 1.8 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HemX PF04375.14 KNZ77375.1 - 1 8.6 7.3 0.53 9.5 2.7 2.4 3 0 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase CENP-H PF05837.12 KNZ77375.1 - 4.1 7.9 9.2 1.3 9.4 5.4 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) COG2 PF06148.11 KNZ77375.1 - 6 7.0 7.3 5.3 7.1 3.2 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CorA PF01544.18 KNZ77375.1 - 7.3 5.8 7.7 2 7.6 4.3 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CENP-T_C PF15511.6 KNZ77378.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KNZ77378.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KNZ77378.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KNZ77378.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ77378.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KNZ77378.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KNZ77379.1 - 3.7e-50 169.7 3.6 4.1e-50 169.5 3.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNZ77379.1 - 2.7e-05 24.5 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNZ77379.1 - 5.8e-05 23.2 0.1 9.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KNZ77379.1 - 0.00035 21.2 2.3 0.00044 20.8 2.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KNZ77379.1 - 0.00072 19.8 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KNZ77379.1 - 0.09 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated DNA_ligase_A_M PF01068.21 KNZ77381.1 - 1.2e-22 80.5 0.5 4.1e-22 78.8 0.5 1.8 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KNZ77381.1 - 5.2e-17 62.7 0.0 1.3e-15 58.1 0.0 2.3 2 0 0 2 2 2 1 DNA ligase N terminus RNA_ligase PF09414.10 KNZ77381.1 - 1.9e-06 28.3 0.1 4.7e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 RNA ligase RINGv PF12906.7 KNZ77382.1 - 5.7e-16 58.4 8.7 9.7e-16 57.6 8.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KNZ77382.1 - 0.016 15.6 9.2 0.026 14.8 9.2 1.4 1 0 0 1 1 1 0 Ring finger domain FLYWCH_u PF16662.5 KNZ77382.1 - 0.029 14.4 0.8 0.062 13.4 0.8 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 zf-RING_4 PF14570.6 KNZ77382.1 - 0.57 10.0 7.1 0.96 9.3 7.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KNZ77382.1 - 1.6 8.9 4.3 3.3 7.8 4.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KNZ77382.1 - 3.8 7.4 6.5 6.8 6.6 6.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TatD_DNase PF01026.21 KNZ77384.1 - 4.8e-41 140.8 0.0 5.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 KNZ77384.1 - 0.035 13.9 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase Amidohydro_3 PF07969.11 KNZ77384.1 - 0.072 12.5 0.0 9.5 5.6 0.0 2.4 2 1 0 2 2 2 0 Amidohydrolase family Z1 PF10593.9 KNZ77385.1 - 0.14 11.6 2.1 0.23 10.9 2.1 1.2 1 0 0 1 1 1 0 Z1 domain 5_nucleotid PF05761.14 KNZ77385.1 - 0.16 10.8 0.8 0.23 10.3 0.8 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF3450 PF11932.8 KNZ77385.1 - 0.91 8.8 8.0 0.62 9.3 5.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 KNZ77385.1 - 4.6 7.8 7.4 1.4 9.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Chromo PF00385.24 KNZ77387.1 - 9.2e-11 41.5 0.2 2.5e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KNZ77387.1 - 1.3e-09 38.0 0.0 5.6e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.6 KNZ77387.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 GEMIN8 PF15348.6 KNZ77387.1 - 0.56 10.5 11.7 0.069 13.5 1.4 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 CNDH2_M PF16869.5 KNZ77387.1 - 1.7 9.3 8.3 0.37 11.5 3.1 2.1 2 0 0 2 2 2 0 PF16858 SAPS PF04499.15 KNZ77387.1 - 2.5 6.8 7.8 3.6 6.3 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRM_1 PF00076.22 KNZ77388.1 - 2.1e-15 56.3 0.1 3.3e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KNZ77388.1 - 0.028 14.5 0.1 0.043 13.9 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif zf-MYND PF01753.18 KNZ77389.1 - 6e-07 29.4 17.3 1.3e-06 28.4 17.3 1.6 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.7 KNZ77389.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.6 KNZ77389.1 - 1.1 9.4 10.7 2.6 8.2 10.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 KH_6 PF15985.5 KNZ77390.1 - 3.6e-15 56.0 0.1 6.4e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 KNZ77390.1 - 1.8e-14 53.2 0.2 3.2e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 KNZ77390.1 - 0.12 13.0 0.1 1.1 10.0 0.1 2.2 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 DUF4551 PF15087.6 KNZ77391.1 - 0.64 8.8 1.7 0.85 8.4 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pox_Ag35 PF03286.14 KNZ77391.1 - 1.9 8.2 10.4 3 7.6 10.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TFIIIC_delta PF12657.7 KNZ77392.1 - 4.5e-16 59.3 0.4 1.1e-15 58.0 0.4 1.7 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 KNZ77392.1 - 3.7e-15 55.7 0.8 7.1e-15 54.8 0.8 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex PQQ_3 PF13570.6 KNZ77392.1 - 0.027 15.0 0.4 0.25 11.9 0.3 2.6 2 0 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 KNZ77392.1 - 0.043 12.5 0.1 0.068 11.8 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 zf-ribbon_3 PF13248.6 KNZ77392.1 - 0.22 11.0 1.6 0.59 9.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 KNZ77392.1 - 4 7.5 7.7 0.5 10.4 0.7 2.9 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Pro-kuma_activ PF09286.11 KNZ77393.1 - 8.2e-37 126.7 0.0 9.7e-36 123.2 0.1 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KNZ77393.1 - 0.00071 18.9 4.7 0.0018 17.6 2.1 2.1 2 0 0 2 2 2 1 Subtilase family FAT PF02259.23 KNZ77394.1 - 9.1e-116 386.9 1.3 9.1e-116 386.9 1.3 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KNZ77394.1 - 1.5e-68 231.3 0.0 3.3e-68 230.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 KNZ77394.1 - 6.5e-53 178.9 0.3 2.8e-50 170.4 0.1 4.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 KNZ77394.1 - 1.9e-38 130.9 0.2 1.9e-38 130.9 0.2 3.0 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 KNZ77394.1 - 1.9e-16 59.6 0.6 5.2e-16 58.2 0.6 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 KNZ77394.1 - 3.5e-12 46.5 11.0 0.0051 17.2 0.0 8.7 8 1 2 10 10 8 3 HEAT repeats TPR_19 PF14559.6 KNZ77394.1 - 3e-07 30.9 0.1 0.026 15.0 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat HEAT PF02985.22 KNZ77394.1 - 5.7e-07 29.2 16.7 0.29 11.5 0.1 10.2 11 0 0 11 11 9 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KNZ77394.1 - 8.5e-06 26.3 0.1 34 5.1 0.0 7.2 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KNZ77394.1 - 0.004 16.7 1.9 17 4.9 0.0 5.3 6 0 0 6 6 6 0 CLASP N terminal DUF3384 PF11864.8 KNZ77394.1 - 0.0053 15.7 1.4 0.22 10.4 0.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3384) TPR_9 PF13371.6 KNZ77394.1 - 0.0057 16.8 2.0 3.1 8.0 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 KNZ77394.1 - 0.0062 17.0 21.9 1.8 9.1 0.0 9.8 12 0 0 12 12 8 2 HEAT-like repeat Cnd1 PF12717.7 KNZ77394.1 - 0.0066 16.5 0.2 2.8 8.0 0.0 4.2 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KNZ77394.1 - 0.0077 14.8 1.7 0.23 10.0 0.4 3.2 1 1 1 2 2 2 1 Adaptin N terminal region TPR_7 PF13176.6 KNZ77394.1 - 0.015 15.2 2.0 0.32 11.1 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ77394.1 - 0.04 14.0 0.3 3.3 8.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF190 PF02641.15 KNZ77394.1 - 0.1 12.9 0.0 0.45 10.9 0.0 2.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 TPR_12 PF13424.6 KNZ77394.1 - 0.12 12.7 0.8 20 5.6 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ77394.1 - 0.52 11.3 3.0 8.7 7.5 0.1 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Cohesin_HEAT PF12765.7 KNZ77394.1 - 0.82 10.0 3.7 7.3 7.0 0.1 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RNase_H PF00075.24 KNZ77395.1 - 0.039 14.1 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 RNase H TPR_12 PF13424.6 KNZ77399.1 - 2.3e-18 66.2 35.3 0.0098 16.2 0.2 12.5 9 4 3 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ77399.1 - 3.5e-11 42.3 26.3 0.39 11.0 1.7 11.8 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ77399.1 - 1.9e-05 24.3 18.2 2.6 8.0 1.1 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ77399.1 - 0.0011 18.8 33.1 4.4 7.3 1.5 11.8 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ77399.1 - 0.0012 19.3 9.4 0.26 11.8 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ77399.1 - 0.0012 19.4 15.7 22 6.2 0.0 8.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 KNZ77399.1 - 0.0068 16.4 0.7 1.6 8.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ77399.1 - 0.066 13.5 16.8 1.9 8.9 1.0 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TFIIS_M PF07500.14 KNZ77399.1 - 0.079 13.4 0.0 0.89 10.1 0.0 2.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Asp PF00026.23 KNZ77400.1 - 2.2e-67 227.7 0.1 2.7e-67 227.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ77400.1 - 1.4e-11 45.0 1.5 2e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ77400.1 - 0.027 15.1 0.4 0.37 11.5 0.1 2.8 2 1 0 2 2 2 0 Aspartyl protease Histone PF00125.24 KNZ77401.1 - 8.6e-43 145.8 2.0 1e-42 145.6 2.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KNZ77401.1 - 3.8e-06 27.0 0.1 7.8e-06 26.0 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KNZ77401.1 - 0.0001 22.6 0.1 0.00048 20.4 0.0 1.8 2 0 0 2 2 2 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KNZ77401.1 - 0.0091 16.3 0.2 0.023 15.0 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1065 PF06358.11 KNZ77401.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) UPF0147 PF03685.13 KNZ77401.1 - 0.062 13.3 0.4 9.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) TFIID-31kDa PF02291.15 KNZ77401.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 KNZ77402.1 - 3.7e-50 169.7 3.6 4.1e-50 169.5 3.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNZ77402.1 - 2.7e-05 24.5 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 KNZ77402.1 - 5.8e-05 23.2 0.1 9.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 KNZ77402.1 - 0.00035 21.2 2.3 0.00044 20.8 2.3 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KNZ77402.1 - 0.00072 19.8 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 KNZ77402.1 - 0.09 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 KNZ77403.1 - 4.4e-07 30.0 0.0 5.3e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KNZ77403.1 - 6.4e-05 23.1 0.1 9.1e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KNZ77403.1 - 0.00014 22.2 0.0 0.00018 21.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KNZ77403.1 - 0.00098 19.4 0.1 0.0018 18.5 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ77403.1 - 0.0019 18.5 0.2 0.0022 18.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KNZ77403.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SIR2 PF02146.17 KNZ77405.1 - 6.3e-38 130.5 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KNZ77405.1 - 1.3e-06 28.3 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) zf-PHD-like PF15446.6 KNZ77405.1 - 0.001 18.7 0.4 0.0019 17.9 0.4 1.3 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain TPP_enzyme_M PF00205.22 KNZ77405.1 - 0.11 12.2 0.0 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Mnd1 PF03962.15 KNZ77406.1 - 0.0042 17.4 0.2 0.0088 16.3 0.2 1.7 1 0 0 1 1 1 1 Mnd1 HTH domain XRN_M PF17846.1 KNZ77406.1 - 2 7.3 13.0 2.5 6.9 13.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain MAJIN PF15077.6 KNZ77406.1 - 2.6 7.8 10.6 3.1 7.5 10.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF5324 PF17258.2 KNZ77407.1 - 0.0017 18.1 6.6 0.023 14.4 0.1 2.4 3 0 0 3 3 3 2 Family of unknown function (DUF5324) Aldo_ket_red PF00248.21 KNZ77408.1 - 3.9e-42 144.4 0.0 2.4e-41 141.9 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 KNZ77409.1 - 9.4e-05 22.2 0.6 0.00025 20.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like DLH PF01738.18 KNZ77410.1 - 1.4e-13 50.9 0.0 1.7e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family PTS_2-RNA PF01885.16 KNZ77412.1 - 7.2e-64 215.2 0.0 8.8e-64 214.9 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RTC4 PF14474.6 KNZ77413.1 - 2.3e-25 89.1 0.1 6e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 RTC4-like domain CPP1-like PF11833.8 KNZ77413.1 - 5.7 6.5 4.7 14 5.3 4.7 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Acetyltransf_7 PF13508.7 KNZ77415.1 - 0.00026 21.3 0.0 0.0005 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ77415.1 - 0.00036 20.5 0.0 0.00066 19.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ77415.1 - 0.002 18.4 0.0 0.0035 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KNZ77416.1 - 2.1e-13 51.1 0.0 3.1e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ77416.1 - 0.00033 20.9 0.0 0.00054 20.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KNZ77416.1 - 0.014 15.5 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KNZ77416.1 - 0.021 14.5 0.1 0.058 13.1 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_hydro_18 PF00704.28 KNZ77417.1 - 7.3e-22 78.5 10.1 1.8e-21 77.2 9.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KNZ77417.1 - 0.001 19.5 8.8 0.001 19.5 8.8 2.9 3 0 0 3 3 3 1 Carbohydrate binding domain DUF2015 PF09435.10 KNZ77418.1 - 1.3e-31 108.8 0.3 1.3e-31 108.7 0.3 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Smr PF01713.21 KNZ77419.1 - 2.8e-09 37.2 0.0 9.4e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 KNZ77419.1 - 7.4e-09 35.9 4.3 1.5e-08 34.9 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DIM1 PF02966.16 KNZ77420.1 - 2.5e-67 224.7 0.0 2.7e-67 224.6 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 KNZ77420.1 - 2e-05 24.5 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredox_DsbH PF03190.15 KNZ77420.1 - 0.044 13.7 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.6 KNZ77420.1 - 0.056 13.8 0.2 0.085 13.2 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like CorA PF01544.18 KNZ77421.1 - 0.27 10.5 2.8 0.41 9.9 2.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein VPS9 PF02204.18 KNZ77422.1 - 8.6e-17 61.3 0.1 2.3e-13 50.2 0.0 2.7 3 0 0 3 3 3 2 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KNZ77422.1 - 0.018 15.4 0.3 0.04 14.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) Cas_Csd1 PF09709.10 KNZ77422.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) E3_binding PF02817.17 KNZ77424.1 - 0.64 10.4 4.8 0.34 11.3 0.8 2.5 2 0 0 2 2 2 0 e3 binding domain IlvN PF07991.12 KNZ77425.1 - 6e-47 159.3 0.2 9.9e-47 158.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain RRM_1 PF00076.22 KNZ77425.1 - 2.1e-40 136.3 0.2 3.3e-20 71.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IlvC PF01450.19 KNZ77425.1 - 1.8e-17 64.0 0.5 4e-17 62.8 0.5 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain RBM39linker PF15519.6 KNZ77425.1 - 7e-14 52.7 2.2 3.9e-12 47.1 2.2 2.8 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein F420_oxidored PF03807.17 KNZ77425.1 - 4.9e-08 33.4 0.2 1.1e-07 32.3 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KNZ77425.1 - 0.00018 21.7 0.1 0.00042 20.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RRM_3 PF08777.11 KNZ77425.1 - 0.00047 20.2 0.4 0.083 12.9 0.0 2.8 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 KNZ77425.1 - 0.001 18.9 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KNZ77425.1 - 0.016 14.8 0.0 2.3 7.8 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ77425.1 - 0.079 13.1 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 KNZ77425.1 - 0.08 13.0 0.1 9.7 6.3 0.1 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif CDC45 PF02724.14 KNZ77425.1 - 8.2 4.6 11.3 15 3.7 11.3 1.3 1 0 0 1 1 1 0 CDC45-like protein adh_short_C2 PF13561.6 KNZ77426.1 - 2.1e-53 181.3 0.2 2.5e-52 177.8 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ77426.1 - 1.1e-39 135.9 0.1 2.8e-39 134.6 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ77426.1 - 4.8e-11 42.9 0.1 2.5e-09 37.3 0.1 2.1 1 1 0 1 1 1 1 KR domain Cupin_2 PF07883.11 KNZ77427.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Pex16 PF08610.10 KNZ77428.1 - 1.6e-107 359.4 2.1 1.8e-107 359.3 2.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF1489 PF07370.11 KNZ77429.1 - 0.0037 17.0 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1489) CppA_C PF14507.6 KNZ77429.1 - 0.056 14.2 0.1 10 6.9 0.1 2.3 2 0 0 2 2 2 0 CppA C-terminal WES_acyltransf PF03007.16 KNZ77429.1 - 0.058 13.1 1.2 0.3 10.8 0.0 2.3 3 0 0 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain ApoC-I PF04691.12 KNZ77429.1 - 0.14 12.1 2.1 1.6 8.7 0.4 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) CorA PF01544.18 KNZ77430.1 - 3.1e-20 72.7 0.2 2.7e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DDT PF02791.17 KNZ77430.1 - 0.16 12.3 0.1 2 8.8 0.0 2.5 3 0 0 3 3 3 0 DDT domain RRP36 PF06102.12 KNZ77431.1 - 1.6e-39 135.6 19.8 1.6e-39 135.6 19.8 2.0 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 bMG5 PF17972.1 KNZ77431.1 - 9.9 6.6 8.7 8.3 6.8 0.8 2.6 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG5 domain D-ser_dehydrat PF14031.6 KNZ77432.1 - 4.1e-25 88.3 0.0 3.3e-24 85.4 0.0 2.3 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 KNZ77432.1 - 1.4e-05 24.8 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ras PF00071.22 KNZ77433.1 - 3e-46 157.0 0.0 3.7e-46 156.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ77433.1 - 1.5e-31 109.1 0.0 1.9e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ77433.1 - 1.9e-12 47.0 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ77433.1 - 2.3e-05 24.0 0.0 0.00076 19.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNZ77433.1 - 0.00013 22.0 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KNZ77433.1 - 0.00037 19.9 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATPase PF06745.13 KNZ77433.1 - 0.0018 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_7 PF12775.7 KNZ77433.1 - 0.0026 17.3 0.0 0.0036 16.8 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 KNZ77433.1 - 0.0028 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DAP3 PF10236.9 KNZ77433.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 KNZ77433.1 - 0.015 15.6 0.1 0.018 15.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ77433.1 - 0.023 15.1 0.1 0.03 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KNZ77433.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KNZ77433.1 - 0.029 14.3 0.0 0.63 9.9 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 KNZ77433.1 - 0.045 14.3 0.0 0.05 14.1 0.0 1.3 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KNZ77433.1 - 0.097 12.4 0.0 3.2 7.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 KNZ77433.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KNZ77433.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 KNZ77433.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_30 PF13604.6 KNZ77433.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain GT87 PF09594.10 KNZ77434.1 - 0.019 14.7 0.8 0.034 13.9 0.2 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 87 LPG_synthase_TM PF03706.13 KNZ77434.1 - 0.065 12.8 0.2 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Isochorismatase PF00857.20 KNZ77435.1 - 2.1e-23 83.4 0.0 4.7e-23 82.3 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family TMEM51 PF15345.6 KNZ77436.1 - 0.043 13.7 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 LapA_dom PF06305.11 KNZ77436.1 - 0.3 10.9 1.1 0.55 10.1 1.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain G_glu_transpept PF01019.21 KNZ77438.1 - 8.6e-132 440.5 0.0 1.3e-131 439.9 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Galactosyl_T PF01762.21 KNZ77440.1 - 8.8e-09 35.5 0.0 0.0012 18.7 0.0 2.5 2 1 0 2 2 2 2 Galactosyltransferase Glyco_trans_2_3 PF13632.6 KNZ77440.1 - 0.38 10.6 4.1 0.6 10.0 1.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase family group 2 GST_N_3 PF13417.6 KNZ77441.1 - 1.7e-10 41.1 0.0 4.5e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ77441.1 - 2.3e-08 34.2 0.0 5.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ77441.1 - 0.0002 21.3 0.0 0.00048 20.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KNZ77441.1 - 0.00027 21.2 0.0 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ77441.1 - 0.0011 19.2 0.2 0.053 13.8 0.1 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ77441.1 - 0.0021 18.2 0.1 0.031 14.5 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SGS PF05002.15 KNZ77442.1 - 3.8e-34 116.6 4.7 5.6e-34 116.1 4.7 1.2 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KNZ77442.1 - 2.7e-09 37.9 0.0 5.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 CS domain DHFR_1 PF00186.19 KNZ77443.1 - 2.8e-29 101.9 0.0 4.6e-29 101.2 0.0 1.5 1 1 0 1 1 1 1 Dihydrofolate reductase Ribosomal_L36 PF00444.18 KNZ77444.1 - 1.7e-17 63.3 11.9 2.4e-17 62.8 11.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 EamA PF00892.20 KNZ77445.1 - 0.00068 19.8 28.6 0.0055 16.9 18.7 4.1 3 1 1 4 4 4 2 EamA-like transporter family Tlr3_TMD PF17968.1 KNZ77445.1 - 9.6 6.5 11.4 0.23 11.7 2.2 2.7 2 0 0 2 2 2 0 Toll-like receptor 3 trans-membrane domain Metallophos PF00149.28 KNZ77446.1 - 6.9e-33 114.9 0.0 5.8e-32 111.9 0.0 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase MPC PF03650.13 KNZ77447.1 - 1.4e-19 70.3 0.1 2.3e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Ribosomal_S17 PF00366.20 KNZ77447.1 - 9e-15 54.5 0.0 1.4e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 KNZ77447.1 - 2.1e-11 44.0 0.1 3.7e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal DNA_ligase_A_M PF01068.21 KNZ77448.1 - 2.2e-65 220.1 0.1 3.6e-65 219.4 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KNZ77448.1 - 2.6e-43 148.3 0.6 5.1e-43 147.4 0.6 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KNZ77448.1 - 2.1e-25 89.2 0.0 6.8e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KNZ77448.1 - 0.0003 21.1 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 KNZ77448.1 - 0.035 14.1 0.1 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain NUDIX PF00293.28 KNZ77450.1 - 9.9e-23 80.6 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain tRNA_lig_CPD PF08302.11 KNZ77453.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Kelch_3 PF13415.6 KNZ77456.1 - 1.9e-28 98.1 6.4 2.8e-08 33.9 0.0 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KNZ77456.1 - 1.6e-27 95.3 10.3 1e-05 25.4 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 KNZ77456.1 - 7.1e-20 70.3 3.7 5.1e-06 26.0 0.1 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 KNZ77456.1 - 2.5e-18 65.7 3.9 1.4e-05 25.2 0.0 5.2 4 1 1 5 5 5 3 Kelch motif DUF4110 PF13422.6 KNZ77456.1 - 3.3e-18 65.5 0.0 3.3e-18 65.5 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 KNZ77456.1 - 2.7e-17 62.3 9.3 0.0011 18.9 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KNZ77456.1 - 2.1e-10 40.1 15.1 7.8e-06 25.7 0.1 6.0 6 1 0 6 6 6 3 Kelch motif Exo_endo_phos_2 PF14529.6 KNZ77457.1 - 7.4e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.24 KNZ77457.1 - 2e-08 34.5 0.0 1.3e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ77457.1 - 1.9e-06 28.5 0.2 4.4e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1043 PF06295.12 KNZ77458.1 - 0.081 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Cation_efflux PF01545.21 KNZ77458.1 - 0.42 10.3 7.5 1.5 8.5 0.0 2.5 3 0 0 3 3 3 0 Cation efflux family YtxH PF12732.7 KNZ77458.1 - 0.59 10.7 4.5 0.61 10.6 2.2 2.3 2 0 0 2 2 2 0 YtxH-like protein DUF883 PF05957.13 KNZ77458.1 - 1.7 9.3 8.7 0.087 13.4 0.7 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1211 PF06736.11 KNZ77459.1 - 0.051 14.0 2.4 0.083 13.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1211) ELFV_dehydrog PF00208.21 KNZ77461.1 - 5.6e-72 242.4 0.3 6.8e-72 242.1 0.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KNZ77461.1 - 2.3e-48 163.4 0.0 4e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain zf-CCHC PF00098.23 KNZ77462.1 - 0.16 12.1 1.5 0.58 10.3 1.5 2.1 1 0 0 1 1 1 0 Zinc knuckle zf-RVT PF13966.6 KNZ77463.1 - 7.7e-05 23.3 0.1 0.00017 22.3 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn-ribbon_8 PF09723.10 KNZ77463.1 - 0.0045 17.1 0.9 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KNZ77463.1 - 0.012 15.6 2.8 0.012 15.6 2.8 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Exo70 PF03081.15 KNZ77465.1 - 5.4e-35 121.2 3.5 7.4e-34 117.4 1.2 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit UPF0193 PF05250.11 KNZ77465.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) DUF2120 PF09893.9 KNZ77465.1 - 0.03 14.4 2.8 0.83 9.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DUF4602 PF15375.6 KNZ77465.1 - 0.048 14.0 0.1 0.048 14.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) GCR PF02155.15 KNZ77465.1 - 0.087 11.9 0.2 0.16 11.0 0.2 1.4 1 0 0 1 1 1 0 Glucocorticoid receptor DUF883 PF05957.13 KNZ77465.1 - 6 7.6 5.4 5.1 7.8 1.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Peptidase_M36 PF02128.15 KNZ77466.1 - 7.4e-141 469.6 4.3 8.8e-141 469.4 4.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KNZ77466.1 - 0.0044 16.8 0.1 0.015 15.1 0.1 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KNZ77466.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 KNZ77466.1 - 0.13 12.8 4.0 0.39 11.2 4.0 1.9 1 1 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain CBFD_NFYB_HMF PF00808.23 KNZ77467.1 - 5.9e-27 93.8 0.4 9.6e-27 93.1 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ77467.1 - 8.7e-05 22.9 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KNZ77467.1 - 0.0037 17.3 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T_C PF15511.6 KNZ77467.1 - 0.016 15.3 0.0 0.021 14.9 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PAN_3 PF08277.12 KNZ77467.1 - 0.088 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 PAN-like domain GMC_oxred_N PF00732.19 KNZ77468.1 - 3e-69 233.7 0.0 3.7e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ77468.1 - 8.8e-36 123.6 0.1 7.9e-35 120.5 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KNZ77468.1 - 1.4e-05 24.4 0.1 0.02 14.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KNZ77468.1 - 0.00044 19.6 0.1 0.0018 17.6 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KNZ77468.1 - 0.00069 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ77468.1 - 0.0016 18.6 0.0 0.0047 17.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ77468.1 - 0.011 15.4 0.1 0.084 12.4 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KNZ77468.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain SR-25 PF10500.9 KNZ77469.1 - 0.0083 15.8 0.1 0.0083 15.8 0.1 3.7 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein SOG2 PF10428.9 KNZ77469.1 - 1.4 8.0 12.6 1.8 7.7 12.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 KNZ77469.1 - 3.7 7.1 10.1 7.3 6.1 10.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF572) Pkinase PF00069.25 KNZ77470.1 - 1.2e-14 54.3 0.0 7.7e-07 28.7 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77470.1 - 0.0043 16.4 0.0 3.4 6.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ77472.1 - 1e-10 41.4 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77472.1 - 0.00014 21.3 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ77472.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RVT PF13966.6 KNZ77473.1 - 0.0025 18.5 5.2 0.019 15.7 4.2 2.5 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ77473.1 - 0.012 15.6 0.3 0.029 14.3 0.3 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF35_N PF12172.8 KNZ77473.1 - 0.026 14.4 0.3 0.051 13.5 0.3 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 KNZ77473.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Atg29_N PF18388.1 KNZ77474.1 - 0.0065 16.3 0.3 0.016 15.0 0.3 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain GHMP_kinases_C PF08544.13 KNZ77475.1 - 0.076 13.4 0.6 0.091 13.1 0.6 1.2 1 0 0 1 1 1 0 GHMP kinases C terminal PIF1 PF05970.14 KNZ77479.1 - 1.1e-109 367.0 0.0 1.3e-109 366.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77479.1 - 1.3e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KNZ77479.1 - 2.7e-06 25.7 0.0 3.7e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ77479.1 - 0.00078 19.2 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KNZ77479.1 - 0.0014 18.4 0.4 0.18 11.5 0.2 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KNZ77479.1 - 0.0065 16.9 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain 4HPAD_g_N PF18671.1 KNZ77479.1 - 0.014 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal ResIII PF04851.15 KNZ77479.1 - 0.022 14.8 0.0 0.064 13.3 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2791 PF10923.8 KNZ77479.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Helitron_like_N PF14214.6 KNZ77480.1 - 5.3e-64 215.9 0.1 6.6e-64 215.6 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ77480.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) DUF1664 PF07889.12 KNZ77481.1 - 0.0014 18.7 9.9 0.023 14.8 2.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) XhlA PF10779.9 KNZ77481.1 - 0.02 15.1 1.3 0.02 15.1 1.3 2.3 2 1 1 3 3 2 0 Haemolysin XhlA LRRFIP PF09738.9 KNZ77481.1 - 0.024 14.1 18.8 0.032 13.7 18.8 1.2 1 0 0 1 1 1 0 LRRFIP family DUF2968 PF11180.8 KNZ77481.1 - 0.024 14.2 1.2 0.024 14.2 1.2 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) ERM PF00769.19 KNZ77481.1 - 0.033 14.0 19.0 0.051 13.4 19.0 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Fez1 PF06818.15 KNZ77481.1 - 0.042 14.3 21.2 0.036 14.5 17.7 1.9 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 KNZ77481.1 - 0.051 13.8 16.7 0.12 12.6 3.3 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Leu_zip PF15294.6 KNZ77481.1 - 0.051 13.1 16.1 0.092 12.2 13.5 1.9 1 1 0 1 1 1 0 Leucine zipper Spc7 PF08317.11 KNZ77481.1 - 0.053 12.4 19.4 0.063 12.2 19.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RepA_C PF04796.12 KNZ77481.1 - 0.075 13.1 2.3 0.29 11.2 0.2 2.1 1 1 1 2 2 2 0 Plasmid encoded RepA protein DUF4200 PF13863.6 KNZ77481.1 - 0.092 13.1 20.3 0.052 14.0 16.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FapA PF03961.13 KNZ77481.1 - 0.13 10.9 7.3 0.15 10.6 7.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CALCOCO1 PF07888.11 KNZ77481.1 - 0.14 11.0 19.1 0.18 10.6 19.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TSC22 PF01166.18 KNZ77481.1 - 0.15 12.4 10.7 3.2 8.1 1.5 3.6 1 1 3 4 4 4 0 TSC-22/dip/bun family Mei5 PF10376.9 KNZ77481.1 - 0.21 11.4 15.9 0.37 10.6 15.9 1.5 1 1 0 1 1 1 0 Double-strand recombination repair protein YabA PF06156.13 KNZ77481.1 - 0.23 12.1 15.3 0.41 11.3 5.6 2.9 1 1 2 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 KNZ77481.1 - 0.3 11.6 22.5 0.075 13.6 16.5 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4446 PF14584.6 KNZ77481.1 - 0.32 11.0 7.7 1 9.3 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Tropomyosin_1 PF12718.7 KNZ77481.1 - 0.39 10.8 22.1 0.74 10.0 11.5 2.5 1 1 1 2 2 2 0 Tropomyosin like Nup54 PF13874.6 KNZ77481.1 - 0.57 10.3 10.9 0.8 9.8 10.9 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 HALZ PF02183.18 KNZ77481.1 - 0.78 10.0 14.0 3.2 8.0 2.4 3.9 4 1 0 4 4 3 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 KNZ77481.1 - 0.84 9.4 22.1 1.1 9.1 20.9 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Syntaxin-6_N PF09177.11 KNZ77481.1 - 1 10.0 10.0 5 7.7 6.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Wtap PF17098.5 KNZ77481.1 - 1.2 9.0 14.8 1.1 9.2 8.6 2.3 1 1 1 2 2 2 0 WTAP/Mum2p family TMF_TATA_bd PF12325.8 KNZ77481.1 - 1.9 8.7 15.0 3.7 7.8 11.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 KNZ77481.1 - 2 8.5 21.6 3.3 7.8 16.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 KNZ77481.1 - 2.2 8.1 10.8 11 5.9 0.6 2.7 1 1 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 KNZ77481.1 - 2.3 8.7 7.8 1.2e+02 3.3 7.1 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 KNZ77481.1 - 2.3 8.9 10.3 32 5.2 0.5 3.2 1 1 2 3 3 3 0 SlyX DUF4407 PF14362.6 KNZ77481.1 - 2.4 7.4 9.7 3 7.1 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 KNZ77481.1 - 2.5 8.9 13.9 6.5 7.6 5.3 2.2 1 1 1 2 2 2 0 Occludin homology domain HIP1_clath_bdg PF16515.5 KNZ77481.1 - 2.6 8.7 20.4 0.63 10.7 8.6 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 KNZ77481.1 - 4.6 6.2 16.3 1.5 7.9 1.5 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 KNZ77481.1 - 5.1 7.4 14.0 4 7.7 11.1 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 KNZ77481.1 - 6.8 6.5 18.6 6.7 6.5 9.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Plk4_PB2 PF18409.1 KNZ77481.1 - 8.7 7.1 11.2 39 5.0 0.8 2.8 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 bZIP_1 PF00170.21 KNZ77481.1 - 9.6 6.4 13.4 0.46 10.6 1.6 3.0 1 1 2 3 3 3 0 bZIP transcription factor gag-asp_proteas PF13975.6 KNZ77483.1 - 8.7e-07 29.4 0.0 2.3e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ77483.1 - 3e-06 27.8 0.0 6.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ77483.1 - 0.0042 16.9 0.4 0.09 12.6 0.3 2.6 1 1 2 3 3 3 1 Aspartyl protease Asp_protease_2 PF13650.6 KNZ77486.1 - 0.019 15.6 0.0 0.033 14.8 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KNZ77486.1 - 0.044 14.3 0.1 0.066 13.8 0.1 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KNZ77486.1 - 0.06 13.1 1.1 0.082 12.7 0.3 1.7 2 1 0 2 2 2 0 Retroviral aspartyl protease GUN4_N PF16416.5 KNZ77486.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal CPSase_L_D2 PF02786.17 KNZ77488.1 - 2.8e-07 30.2 0.1 3e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain MTES_1575 PF18741.1 KNZ77488.1 - 0.025 14.7 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 REase_MTES_1575 Sas6_CC PF18594.1 KNZ77490.1 - 0.065 13.0 2.7 1.1 9.0 0.5 3.1 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain Spc42p PF11544.8 KNZ77490.1 - 0.78 9.8 13.9 1.7 8.7 1.0 3.1 1 1 2 3 3 3 0 Spindle pole body component Spc42p Spc7 PF08317.11 KNZ77490.1 - 1.2 8.0 29.1 0.01 14.8 11.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 KNZ77490.1 - 1.2 9.7 26.4 2.4 8.7 21.5 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 KNZ77490.1 - 2.7 8.2 27.7 7.3 6.8 27.7 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Tli4_N PF18443.1 KNZ77490.1 - 9.6 6.6 7.9 7.5 6.9 5.1 2.1 1 1 1 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain zf-C4H2 PF10146.9 KNZ77490.1 - 9.7 6.4 21.6 15 5.8 21.6 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Chromo PF00385.24 KNZ77493.1 - 0.06 13.3 2.9 0.25 11.3 2.9 2.0 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Nif11 PF07862.11 KNZ77494.1 - 0.017 15.4 0.5 0.22 11.9 0.0 2.6 2 0 0 2 2 2 0 Nif11 domain Motile_Sperm PF00635.26 KNZ77496.1 - 1.9e-26 92.1 0.1 9.5e-26 89.8 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 KNZ77496.1 - 0.025 14.8 0.1 0.066 13.4 0.1 1.7 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TonB_N PF16031.5 KNZ77496.1 - 3.3 8.2 19.4 0.39 11.2 8.8 2.6 2 0 0 2 2 2 0 TonB polyproline region ABC_membrane PF00664.23 KNZ77497.1 - 1.1e-107 359.8 26.3 9.7e-58 196.0 9.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ77497.1 - 5.6e-69 231.0 0.1 3.4e-33 115.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ77497.1 - 4.2e-15 55.8 0.3 8.9e-05 22.0 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KNZ77497.1 - 4.9e-08 33.1 0.6 0.0018 18.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KNZ77497.1 - 1.2e-07 31.3 0.8 0.015 15.1 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 KNZ77497.1 - 1.5e-06 27.3 0.3 0.0042 15.9 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 KNZ77497.1 - 1.8e-06 28.4 3.5 0.0022 18.4 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KNZ77497.1 - 3.8e-06 27.2 1.3 0.15 12.4 0.1 3.8 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.6 KNZ77497.1 - 6.6e-06 26.1 0.0 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KNZ77497.1 - 1.1e-05 24.8 0.0 0.027 13.7 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 KNZ77497.1 - 2.8e-05 24.1 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 KNZ77497.1 - 8.7e-05 22.3 2.6 0.51 10.0 0.1 3.5 2 2 0 2 2 2 2 AAA domain G-alpha PF00503.20 KNZ77497.1 - 0.00027 20.2 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.6 KNZ77497.1 - 0.0014 18.2 1.2 0.93 9.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KNZ77497.1 - 0.0019 18.8 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KNZ77497.1 - 0.0021 18.6 0.3 3.7 8.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 KNZ77497.1 - 0.0026 18.0 3.0 3.1 8.1 0.4 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 KNZ77497.1 - 0.0032 17.0 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 KNZ77497.1 - 0.0035 17.5 0.0 3 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KNZ77497.1 - 0.0079 16.2 0.1 3.8 7.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 KNZ77497.1 - 0.008 16.1 0.1 5.7 6.8 0.1 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.18 KNZ77497.1 - 0.011 15.1 0.1 3.4 7.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 KNZ77497.1 - 0.011 14.9 0.0 2.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 KNZ77497.1 - 0.015 15.4 2.3 6.7 6.7 0.1 3.7 4 1 0 4 4 3 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KNZ77497.1 - 0.017 15.2 0.1 8 6.6 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRK PF00485.18 KNZ77497.1 - 0.02 14.6 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KNZ77497.1 - 0.023 15.0 0.1 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KNZ77497.1 - 0.029 14.8 0.1 13 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 KNZ77497.1 - 0.032 13.4 0.1 0.98 8.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 KNZ77497.1 - 0.064 13.0 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 KNZ77497.1 - 0.095 11.7 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pkinase PF00069.25 KNZ77498.1 - 1.7e-70 237.4 0.0 2.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77498.1 - 4.2e-30 104.9 0.0 5.6e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KNZ77498.1 - 1.2e-09 38.7 3.8 2.7e-09 37.6 3.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KNZ77498.1 - 3.5e-07 29.5 0.2 5.4e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KNZ77498.1 - 0.00092 18.6 0.0 0.0023 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 KNZ77498.1 - 0.0029 17.3 0.0 0.32 10.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KNZ77498.1 - 0.038 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ77498.1 - 0.062 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-patch PF01585.23 KNZ77499.1 - 5.3e-05 23.0 0.0 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 KNZ77499.1 - 0.015 15.4 0.1 0.83 9.8 0.0 2.8 2 0 0 2 2 2 0 G-patch domain F-box-like PF12937.7 KNZ77500.1 - 7e-11 41.9 0.6 5.8e-10 38.9 0.0 2.8 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 KNZ77500.1 - 0.00073 19.9 2.6 14 6.3 0.0 5.0 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) zf_C2H2_10 PF18414.1 KNZ77500.1 - 0.13 11.8 0.2 0.46 10.1 0.2 1.9 1 0 0 1 1 1 0 C2H2 type zinc-finger PQ-loop PF04193.14 KNZ77501.1 - 3.1e-23 81.3 15.2 4.7e-18 64.7 0.8 3.8 4 0 0 4 4 4 2 PQ loop repeat HTH_Bact PF18768.1 KNZ77501.1 - 0.011 15.2 0.6 0.087 12.4 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain DUF4231 PF14015.6 KNZ77501.1 - 0.19 12.2 1.5 3 8.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) MutS_V PF00488.21 KNZ77502.1 - 6.6e-33 114.3 0.0 2.2e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 KNZ77502.1 - 2.8e-32 112.5 1.1 5.2e-32 111.6 0.1 2.0 2 0 0 2 2 2 1 MutS domain III Band_7 PF01145.25 KNZ77502.1 - 1.8e-19 70.5 0.7 3.1e-19 69.7 0.7 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF4916 PF16262.5 KNZ77502.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) Herpes_UL14 PF03580.14 KNZ77502.1 - 4 7.7 6.9 4.9 7.4 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus UL14-like protein Mito_carr PF00153.27 KNZ77503.1 - 3.1e-18 65.5 0.3 5.6e-09 35.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclin_N PF00134.23 KNZ77504.1 - 4.5e-10 39.4 0.0 1.2e-09 38.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Tup_N PF08581.10 KNZ77504.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 Tup N-terminal zf-CSL PF05207.13 KNZ77505.1 - 4.8e-14 51.8 1.2 8.3e-14 51.1 1.2 1.5 1 0 0 1 1 1 1 CSL zinc finger Pkinase PF00069.25 KNZ77506.1 - 5.5e-53 180.0 0.0 8.7e-52 176.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77506.1 - 6e-28 97.8 0.0 2.9e-25 89.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNZ77506.1 - 1.2e-06 28.1 0.0 2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ77506.1 - 9.8e-06 24.6 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ77506.1 - 0.0083 16.1 0.1 0.24 11.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ77506.1 - 0.0097 15.5 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family BUD22 PF09073.10 KNZ77506.1 - 1.9 7.8 11.0 3.4 6.9 11.0 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 KNZ77506.1 - 2.9 6.0 9.7 4.2 5.5 9.7 1.2 1 0 0 1 1 1 0 Nop14-like family ADH_zinc_N PF00107.26 KNZ77507.1 - 6.2e-14 52.1 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ77507.1 - 2e-10 40.5 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KNZ77507.1 - 0.00043 21.4 0.1 0.0013 19.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ77507.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DDE_1 PF03184.19 KNZ77508.1 - 0.00035 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase_fungal PF17667.1 KNZ77510.1 - 1.3e-37 129.5 0.0 2.7e-22 79.1 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 KNZ77510.1 - 0.00014 21.9 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ77510.1 - 0.0062 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ77510.1 - 0.078 12.3 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_H PF00075.24 KNZ77511.1 - 7.6e-08 32.6 0.1 1.9e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 RNase H rhaM PF05336.13 KNZ77511.1 - 0.0022 18.0 1.9 0.0022 18.0 1.9 2.1 3 0 0 3 3 3 1 L-rhamnose mutarotase RVT_3 PF13456.6 KNZ77511.1 - 0.032 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Alpha_kinase PF02816.18 KNZ77517.1 - 1.6e-09 38.2 0.3 4.6e-09 36.7 0.3 1.8 1 0 0 1 1 1 1 Alpha-kinase family Aminotran_1_2 PF00155.21 KNZ77518.1 - 8.9e-17 61.3 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KNZ77518.1 - 2.7e-11 42.9 0.0 3.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase ADH_zinc_N PF00107.26 KNZ77519.1 - 1.1e-15 57.7 0.0 2.5e-15 56.6 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ77519.1 - 2.6e-08 33.7 0.0 4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KNZ77519.1 - 0.00028 21.9 0.0 0.00042 21.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ77519.1 - 0.19 11.6 0.0 0.55 10.1 0.0 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase zf-CCHC PF00098.23 KNZ77520.1 - 0.025 14.6 0.7 0.025 14.6 0.7 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ77520.1 - 0.028 14.1 0.6 0.057 13.2 0.6 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger DSPc PF00782.20 KNZ77525.1 - 2.5e-25 88.8 0.0 1.4e-20 73.5 0.0 3.1 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ77525.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF2415 PF10313.9 KNZ77526.1 - 9.1e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 KNZ77526.1 - 0.004 17.1 3.4 2.2 8.3 0.1 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40 PF00400.32 KNZ77526.1 - 0.5 11.3 5.9 1.7e+02 3.3 0.0 5.2 4 1 0 4 4 4 0 WD domain, G-beta repeat GalKase_gal_bdg PF10509.9 KNZ77528.1 - 2.1e-14 52.8 0.8 7.9e-08 31.7 0.0 2.4 2 0 0 2 2 2 2 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 KNZ77528.1 - 4.2e-14 52.5 2.7 8.7e-14 51.5 1.7 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KNZ77528.1 - 5.1e-06 26.8 0.3 1.7e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal UPF0014 PF03649.13 KNZ77529.1 - 1.3e-65 221.1 20.2 1.7e-65 220.8 20.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) BPD_transp_1 PF00528.22 KNZ77529.1 - 0.00015 21.5 12.0 0.00015 21.5 12.0 2.1 1 1 0 2 2 2 1 Binding-protein-dependent transport system inner membrane component HSP20 PF00011.21 KNZ77530.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.4 1 1 0 1 1 1 0 Hsp20/alpha crystallin family NAD_binding_8 PF13450.6 KNZ77531.1 - 3e-05 24.2 0.1 0.0012 19.0 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KNZ77531.1 - 0.038 13.3 0.0 3.2 6.9 0.0 2.4 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Ala_racemase_N PF01168.20 KNZ77532.1 - 2.8e-17 63.1 0.0 1.2e-16 61.0 0.0 1.8 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Hydrolase_like PF13242.6 KNZ77532.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like FAST_2 PF08368.12 KNZ77532.1 - 0.12 13.2 0.1 0.3 11.9 0.1 1.7 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Glyco_transf_22 PF03901.17 KNZ77533.1 - 2.3e-39 135.8 25.1 2.9e-39 135.5 25.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ABC2_membrane PF01061.24 KNZ77534.1 - 5.1e-36 124.1 20.7 9.3e-36 123.2 20.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KNZ77534.1 - 2.1e-26 93.0 0.0 3.6e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KNZ77534.1 - 8.1e-05 22.6 0.1 0.078 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KNZ77534.1 - 0.00045 19.9 0.1 0.0012 18.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KNZ77534.1 - 0.0019 18.1 0.1 0.0037 17.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase EGF_2 PF07974.13 KNZ77534.1 - 0.0087 16.4 14.9 0.0087 16.4 14.9 3.7 3 0 0 3 3 2 2 EGF-like domain AAA_16 PF13191.6 KNZ77534.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KNZ77534.1 - 0.026 14.8 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KNZ77534.1 - 0.029 13.8 0.0 0.082 12.3 0.0 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KNZ77534.1 - 0.042 14.1 0.1 0.11 12.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 KNZ77534.1 - 0.043 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 KNZ77534.1 - 0.062 12.9 0.2 0.1 12.2 0.2 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 KNZ77534.1 - 0.13 11.9 0.1 0.42 10.2 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KNZ77534.1 - 0.16 12.5 0.0 0.47 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KNZ77534.1 - 0.2 11.8 0.1 0.39 10.8 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 KNZ77534.1 - 1.9 7.5 27.5 0.73 8.9 24.6 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Laminin_EGF PF00053.24 KNZ77534.1 - 5.9 7.1 26.8 1.8 8.8 5.1 3.4 2 1 1 3 3 3 0 Laminin EGF domain PIF1 PF05970.14 KNZ77535.1 - 8.5e-17 61.4 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase DUF262 PF03235.14 KNZ77536.1 - 2.6e-12 47.4 0.2 3.4e-12 47.0 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF262 DASH_Dad4 PF08650.10 KNZ77537.1 - 0.14 12.2 0.4 0.22 11.5 0.4 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad4 Pribosyltran_N PF13793.6 KNZ77538.1 - 3.7e-48 162.3 1.5 1.7e-47 160.1 0.1 2.6 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KNZ77538.1 - 3.4e-37 128.3 2.2 2.9e-34 118.7 1.0 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KNZ77538.1 - 4.2e-16 58.9 0.6 2.2e-15 56.5 0.2 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KNZ77538.1 - 1.1e-05 25.0 0.3 2.2e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KNZ77538.1 - 0.048 13.1 0.1 0.093 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase ProRS-C_2 PF09181.10 KNZ77539.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal TPR_1 PF00515.28 KNZ77540.1 - 2.5e-19 68.2 1.2 3e-06 26.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ77540.1 - 2.1e-17 61.8 4.6 2.4e-06 27.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ77540.1 - 8.4e-11 41.8 5.3 4.6e-05 23.9 0.5 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ77540.1 - 1.5e-09 37.4 0.5 0.00017 21.2 0.6 2.4 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KNZ77540.1 - 1.5e-09 38.3 1.5 5.9e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ77540.1 - 6.9e-09 35.2 1.6 0.034 14.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ77540.1 - 9.1e-08 32.5 1.9 4.9e-05 23.7 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ77540.1 - 1.3e-07 31.8 11.6 0.00047 20.4 2.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ77540.1 - 2e-06 27.4 4.0 0.0032 17.4 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ77540.1 - 4.3e-05 23.9 4.2 0.033 14.8 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ77540.1 - 0.00019 20.8 0.3 0.00035 19.9 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ77540.1 - 0.0027 17.9 0.4 0.017 15.4 0.2 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SR-25 PF10500.9 KNZ77540.1 - 0.038 13.6 9.9 0.074 12.7 9.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_10 PF13374.6 KNZ77540.1 - 0.11 12.4 10.8 6.3 6.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KNZ77540.1 - 0.24 10.9 1.0 1.4 8.5 0.1 2.5 3 0 0 3 3 3 0 SHNi-TPR TPR_9 PF13371.6 KNZ77540.1 - 0.28 11.4 6.2 2.1 8.6 1.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.12 KNZ77540.1 - 3.1 6.4 6.9 4.4 5.9 6.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TEX19 PF15553.6 KNZ77541.1 - 0.07 13.1 1.0 0.52 10.3 0.4 1.9 1 1 1 2 2 2 0 Testis-expressed protein 19 RINGv PF12906.7 KNZ77543.1 - 2.8e-05 24.2 6.9 5.2e-05 23.3 6.9 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KNZ77543.1 - 0.013 15.8 5.7 0.022 15.1 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KNZ77543.1 - 0.032 14.4 3.7 0.055 13.6 3.7 1.3 1 0 0 1 1 1 0 FANCL C-terminal domain PHD_Oberon PF07227.11 KNZ77543.1 - 0.13 12.1 1.1 0.23 11.3 1.1 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein MMTV_SAg PF01054.17 KNZ77544.1 - 0.26 10.8 0.9 0.33 10.5 0.3 1.5 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen Botulinum_HA-17 PF05588.11 KNZ77545.1 - 0.069 13.3 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Clostridium botulinum HA-17 domain XPA_N PF01286.18 KNZ77546.1 - 0.085 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 XPA protein N-terminal Aminotran_5 PF00266.19 KNZ77547.1 - 8e-08 31.6 0.0 1e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 KNZ77547.1 - 0.011 15.7 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain Aminotran_5 PF00266.19 KNZ77548.1 - 6.8e-13 48.3 0.1 7.7e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KNZ77550.1 - 3.7e-94 315.4 0.1 8.4e-93 310.9 0.1 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KNZ77550.1 - 2.6e-07 29.9 0.7 4.6e-07 29.1 0.7 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KNZ77550.1 - 0.0012 18.0 0.2 0.003 16.8 0.2 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KNZ77550.1 - 0.0017 17.7 0.2 0.0066 15.8 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KNZ77550.1 - 0.0053 16.1 2.9 0.072 12.4 2.8 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KNZ77550.1 - 0.018 13.8 0.2 0.033 12.9 0.2 1.4 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Met_gamma_lyase PF06838.11 KNZ77550.1 - 0.089 11.3 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ThylakoidFormat PF11264.8 KNZ77551.1 - 0.064 12.9 0.0 0.077 12.7 0.0 1.0 1 0 0 1 1 1 0 Thylakoid formation protein Melibiase_2 PF16499.5 KNZ77552.1 - 7.8e-50 169.6 0.7 1.2e-49 169.1 0.7 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KNZ77552.1 - 9.3e-16 57.7 0.5 4.6e-14 52.2 0.1 2.4 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KNZ77552.1 - 2.1e-05 23.6 0.0 4e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Melibiase E1_dh PF00676.20 KNZ77553.1 - 4.4e-111 370.6 0.0 5.2e-111 370.4 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KNZ77553.1 - 7.5e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 KNZ77553.1 - 0.00085 19.1 0.6 0.00085 19.1 0.6 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain COMM_domain PF07258.14 KNZ77553.1 - 0.19 11.8 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 COMM domain RNase_P_Rpp14 PF01900.19 KNZ77554.1 - 1.7e-09 37.9 0.0 1.4e-05 25.2 0.0 2.0 1 1 1 2 2 2 2 Rpp14/Pop5 family YjcB PF15940.5 KNZ77554.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function zf-CCHC PF00098.23 KNZ77557.1 - 8.6e-06 25.6 1.5 2.3e-05 24.2 1.5 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 KNZ77557.1 - 0.028 14.1 0.2 0.028 14.1 0.2 1.7 2 0 0 2 2 2 0 Zinc knuckle HscB_4_cys PF18256.1 KNZ77557.1 - 0.43 10.4 4.3 12 5.8 1.4 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif MitMem_reg PF13012.6 KNZ77558.1 - 0.028 14.9 0.0 0.03 14.7 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function RFX5_N PF18326.1 KNZ77558.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 RFX5 N-terminal domain AAA_6 PF12774.7 KNZ77558.1 - 0.076 12.0 0.0 0.087 11.8 0.0 1.0 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Herpes_Helicase PF02689.14 KNZ77559.1 - 0.034 12.1 0.0 0.034 12.1 0.0 1.0 1 0 0 1 1 1 0 Helicase RNase_H PF00075.24 KNZ77561.1 - 2.5e-06 27.7 0.1 2.5e-05 24.5 0.1 2.3 1 1 0 1 1 1 1 RNase H zf-MYND PF01753.18 KNZ77562.1 - 9.1e-12 44.9 9.6 2.8e-11 43.3 9.6 1.9 1 0 0 1 1 1 1 MYND finger zf_C2H2_13 PF18508.1 KNZ77562.1 - 0.042 13.4 2.8 0.46 10.1 0.6 2.4 1 1 1 2 2 2 0 Zinc finger domain zf-C6H2 PF15801.5 KNZ77562.1 - 0.19 12.1 9.1 0.28 11.5 7.4 2.1 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PPI_Ypi1 PF07491.11 KNZ77563.1 - 7.7e-25 86.5 2.6 7.7e-25 86.5 2.6 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor S10_plectin PF03501.15 KNZ77564.1 - 6.3e-46 154.4 0.4 7.6e-46 154.1 0.4 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 KNZ77564.1 - 0.0073 16.2 0.0 0.012 15.5 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Replic_Relax PF13814.6 KNZ77564.1 - 0.1 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Replication-relaxation HTH_27 PF13463.6 KNZ77564.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Aldose_epim PF01263.20 KNZ77565.1 - 1.4e-19 70.6 0.0 3.7e-09 36.3 0.0 2.9 1 1 1 2 2 2 2 Aldose 1-epimerase Myb_DNA-binding PF00249.31 KNZ77566.1 - 8.1e-39 131.6 5.5 2.4e-13 50.1 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ77566.1 - 7.3e-29 99.8 0.1 2.1e-12 47.1 0.1 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KNZ77566.1 - 4.6e-05 23.2 0.0 0.38 10.7 0.0 2.7 2 1 0 2 2 2 2 Myb DNA-binding like JUPITER PF17054.5 KNZ77566.1 - 0.011 15.3 3.4 0.014 14.8 3.4 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter Myb_DNA-bind_4 PF13837.6 KNZ77566.1 - 0.016 15.6 4.9 1.8 9.0 0.6 3.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 KNZ77566.1 - 0.021 15.0 0.2 6.4 7.0 0.1 2.8 2 1 0 2 2 2 0 Rap1 Myb domain SLIDE PF09111.10 KNZ77566.1 - 0.035 14.1 0.0 2.9 7.9 0.0 2.9 1 1 2 3 3 3 0 SLIDE SANT_DAMP1_like PF16282.5 KNZ77566.1 - 0.058 13.6 0.4 3.8 7.8 0.0 2.7 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 KNZ77566.1 - 0.095 13.0 0.5 11 6.4 0.0 2.6 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like GMP_synt_C PF00958.22 KNZ77567.1 - 3.6e-41 139.1 0.1 6.8e-41 138.2 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 KNZ77567.1 - 2.7e-36 125.1 0.0 4.8e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 KNZ77567.1 - 1.3e-09 37.6 0.3 1.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KNZ77567.1 - 1.6e-07 31.3 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 KNZ77567.1 - 0.0026 17.4 0.1 0.0067 16.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KNZ77567.1 - 0.0033 16.3 0.1 0.0054 15.6 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 KNZ77567.1 - 0.0078 15.7 0.0 0.018 14.5 0.0 1.7 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 KNZ77567.1 - 0.053 13.3 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family Arginosuc_synth PF00764.19 KNZ77567.1 - 0.065 12.5 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 KNZ77567.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MetJ PF01340.20 KNZ77567.1 - 0.18 11.8 0.0 0.52 10.3 0.0 1.7 1 1 1 2 2 2 0 Met Apo-repressor, MetJ XRN_M PF17846.1 KNZ77568.1 - 1.3e-102 344.0 5.9 1.2e-101 340.8 5.9 2.2 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KNZ77568.1 - 2.4e-89 298.9 0.0 3.7e-89 298.3 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KNZ77568.1 - 1.8e-75 253.0 0.0 3.1e-75 252.2 0.0 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KNZ77568.1 - 5.5e-31 106.6 0.0 1.3e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KNZ77568.1 - 9.6e-23 80.1 0.3 2.5e-22 78.8 0.3 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KNZ77568.1 - 4.1e-07 30.0 0.0 9.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SLATT_fungal PF18142.1 KNZ77569.1 - 4.7e-42 142.8 0.4 5.8e-42 142.5 0.4 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SLATT_fungal PF18142.1 KNZ77570.1 - 2.6e-39 133.9 0.3 3.4e-39 133.5 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain RdRP_5 PF07925.11 KNZ77570.1 - 0.065 10.6 0.0 0.081 10.3 0.0 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 DUF4231 PF14015.6 KNZ77570.1 - 0.23 12.0 0.9 0.51 10.8 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Lon_C PF05362.13 KNZ77571.1 - 7.9e-68 228.0 0.1 1.4e-67 227.3 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KNZ77571.1 - 7.5e-35 120.7 0.1 2e-34 119.3 0.1 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KNZ77571.1 - 9.3e-22 77.9 0.0 3.3e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KNZ77571.1 - 3.1e-07 30.5 0.0 5.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KNZ77571.1 - 2.3e-06 27.4 0.0 1.7e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 KNZ77571.1 - 0.0003 20.9 0.0 0.00091 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KNZ77571.1 - 0.0011 19.2 0.1 0.015 15.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 KNZ77571.1 - 0.0012 17.9 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 KNZ77571.1 - 0.0027 18.1 0.0 0.01 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 KNZ77571.1 - 0.0031 17.3 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 KNZ77571.1 - 0.013 16.0 1.2 0.031 14.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KNZ77571.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KNZ77571.1 - 0.037 13.8 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein SPX PF03105.19 KNZ77571.1 - 0.04 13.8 10.0 1.1 9.1 2.1 2.3 2 0 0 2 2 2 0 SPX domain RsgA_GTPase PF03193.16 KNZ77571.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 KNZ77571.1 - 0.064 13.6 0.1 0.84 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase YbaJ PF10757.9 KNZ77571.1 - 0.13 12.8 0.0 0.3 11.7 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ SKI PF01202.22 KNZ77571.1 - 0.14 12.2 0.5 0.34 11.0 0.1 1.9 2 0 0 2 2 1 0 Shikimate kinase ABC_tran PF00005.27 KNZ77571.1 - 0.85 10.1 3.1 0.79 10.2 0.8 2.1 2 0 0 2 2 2 0 ABC transporter RNA_pol_Rpc4 PF05132.14 KNZ77571.1 - 4.6 7.7 8.6 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 AAA_23 PF13476.6 KNZ77571.1 - 4.9 7.6 5.9 3.2 8.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain YibE_F PF07907.11 KNZ77572.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 YibE/F-like protein WD40 PF00400.32 KNZ77573.1 - 8e-160 513.9 71.6 6.3e-11 42.7 0.1 16.8 15 1 1 16 16 16 16 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ77573.1 - 3.6e-60 200.3 16.0 0.0035 17.6 0.0 14.5 2 2 12 14 14 14 14 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ77573.1 - 5e-35 118.7 17.5 0.39 10.7 0.0 15.9 16 0 0 16 16 16 13 WD40-like Beta Propeller Repeat CHAP PF05257.16 KNZ77573.1 - 1.3e-19 70.5 24.5 1.5 9.5 0.0 11.2 3 3 7 10 10 10 6 CHAP domain Ge1_WD40 PF16529.5 KNZ77573.1 - 2.7e-18 66.0 33.0 0.83 8.5 0.0 14.7 1 1 12 13 13 13 7 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KNZ77573.1 - 5.1e-13 49.0 2.2 2.4 7.4 0.0 9.3 6 3 4 10 10 10 2 WD40-like domain Cytochrom_D1 PF02239.16 KNZ77573.1 - 1e-12 47.3 13.7 0.00013 20.6 0.2 7.0 2 1 7 10 10 10 5 Cytochrome D1 heme domain NACHT PF05729.12 KNZ77573.1 - 2.2e-11 43.9 0.0 4.7e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain FeThRed_A PF02941.15 KNZ77573.1 - 4.6e-07 29.9 4.2 62 3.8 0.0 9.2 7 1 3 10 10 10 0 Ferredoxin thioredoxin reductase variable alpha chain AAA_16 PF13191.6 KNZ77573.1 - 0.0001 22.8 0.4 0.00041 20.8 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain ABC_tran PF00005.27 KNZ77573.1 - 0.0063 17.0 0.2 0.038 14.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter APS_kinase PF01583.20 KNZ77573.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase SARS_3b PF12383.8 KNZ77573.1 - 0.0081 16.3 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Severe acute respiratory syndrome coronavirus 3b protein NB-ARC PF00931.22 KNZ77573.1 - 0.0083 15.3 4.5 0.012 14.8 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain AAA_29 PF13555.6 KNZ77573.1 - 0.024 14.4 0.0 0.18 11.6 0.0 2.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ77573.1 - 0.027 14.7 0.0 0.088 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ77573.1 - 0.029 14.7 0.2 0.35 11.3 0.0 3.1 2 0 0 2 2 1 0 RNA helicase Zeta_toxin PF06414.12 KNZ77573.1 - 0.058 12.7 0.0 0.52 9.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin D5_N PF08706.11 KNZ77573.1 - 0.13 12.5 0.9 0.95 9.7 0.4 2.6 2 0 0 2 2 2 0 D5 N terminal like AAA_23 PF13476.6 KNZ77573.1 - 0.35 11.4 6.7 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Proteasome_A_N PF10584.9 KNZ77573.1 - 5.7 6.7 42.7 1.8e+02 1.9 0.0 15.1 17 0 0 17 17 17 0 Proteasome subunit A N-terminal signature Hydrolase_4 PF12146.8 KNZ77574.1 - 1.9e-16 60.1 0.3 4.5e-14 52.3 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ77574.1 - 2.9e-10 40.2 0.9 7.3e-09 35.6 0.4 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ77574.1 - 6.5e-09 36.7 0.1 8.6e-09 36.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 KNZ77574.1 - 7.9e-06 25.9 0.1 0.0008 19.4 0.0 2.9 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KNZ77574.1 - 1.3e-05 24.8 0.0 0.00054 19.6 0.0 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KNZ77574.1 - 0.00037 20.0 0.0 0.0048 16.4 0.0 2.4 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KNZ77574.1 - 0.00093 19.1 0.1 5.8 6.7 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KNZ77574.1 - 0.002 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.12 KNZ77574.1 - 0.005 15.9 0.0 0.007 15.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 KNZ77574.1 - 0.0077 15.9 0.0 0.015 15.0 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.7 KNZ77574.1 - 0.014 15.2 0.0 0.34 10.7 0.0 2.7 3 0 0 3 3 3 0 Alpha/beta hydrolase family FSH1 PF03959.13 KNZ77574.1 - 0.058 13.0 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AXE1 PF05448.12 KNZ77574.1 - 0.073 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 KNZ77574.1 - 0.087 12.5 0.7 0.22 11.2 0.7 1.8 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_4 PF08386.10 KNZ77574.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 KNZ77574.1 - 0.1 12.7 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 KNZ77574.1 - 0.18 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RdRP_2 PF00978.21 KNZ77575.1 - 0.014 14.3 0.2 0.018 14.0 0.2 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase PARP PF00644.20 KNZ77577.1 - 1.9e-14 53.7 1.7 4.6e-12 45.9 1.7 2.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 KNZ77578.1 - 1.4e-10 41.1 2.1 3.9e-08 33.1 1.2 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 KNZ77579.1 - 3.8e-14 52.7 8.1 2.9e-13 49.8 0.4 3.1 2 2 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.20 KNZ77580.1 - 9e-12 45.0 0.3 8.1e-08 32.1 0.1 3.0 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 KNZ77581.1 - 1.4e-25 90.4 0.0 2e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) FOXP-CC PF16159.5 KNZ77582.1 - 0.054 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain Cwf_Cwc_15 PF04889.12 KNZ77584.1 - 0.00029 20.7 2.4 0.00037 20.3 2.4 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 KNZ77584.1 - 0.0038 17.1 5.0 0.0063 16.4 5.0 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region CPSF100_C PF13299.6 KNZ77584.1 - 0.03 14.5 0.7 0.055 13.6 0.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM176 PF14851.6 KNZ77584.1 - 0.071 12.8 1.2 0.12 12.0 1.2 1.3 1 0 0 1 1 1 0 FAM176 family D123 PF07065.14 KNZ77584.1 - 0.32 10.1 2.5 0.33 10.1 1.0 1.7 2 0 0 2 2 2 0 D123 NOA36 PF06524.12 KNZ77584.1 - 0.37 10.1 4.9 0.56 9.5 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein TauD PF02668.16 KNZ77585.1 - 1.6e-39 136.3 0.0 2.1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KNZ77585.1 - 0.0005 19.3 0.0 0.023 13.8 0.0 2.1 2 0 0 2 2 2 2 CsiD DUF971 PF06155.12 KNZ77585.1 - 0.0093 16.6 0.0 0.029 15.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) rve PF00665.26 KNZ77585.1 - 0.017 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain IlvN PF07991.12 KNZ77586.1 - 1.2e-45 155.0 0.0 2.4e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KNZ77586.1 - 6.6e-39 133.5 0.0 1.3e-38 132.5 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Whi5 PF08528.11 KNZ77587.1 - 1.3e-08 34.3 1.4 2.3e-08 33.4 1.4 1.5 1 0 0 1 1 1 1 Whi5 like NUDIX PF00293.28 KNZ77588.1 - 3.4e-12 46.6 0.0 4.9e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Spc7 PF08317.11 KNZ77589.1 - 0.0059 15.5 5.0 0.0092 14.9 5.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Golgin_A5 PF09787.9 KNZ77589.1 - 0.0084 15.6 3.6 0.014 14.9 3.6 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 HIP1_clath_bdg PF16515.5 KNZ77589.1 - 0.024 15.2 4.1 0.055 14.1 4.1 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WD40_alt PF14077.6 KNZ77589.1 - 0.032 14.1 1.9 0.045 13.6 0.0 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif CENP-H PF05837.12 KNZ77589.1 - 0.055 13.9 4.3 0.13 12.7 4.3 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 KNZ77589.1 - 0.082 13.4 8.3 9.7 6.7 8.2 2.5 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 KNZ77589.1 - 0.6 9.9 8.6 4.6 7.1 3.1 2.8 2 1 1 3 3 3 0 Septum formation initiator GIT_CC PF16559.5 KNZ77589.1 - 1.4 8.8 4.3 27 4.7 2.7 3.0 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 KNZ77589.1 - 1.5 9.3 4.4 21 5.6 0.5 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Vps26 PF03643.15 KNZ77590.1 - 5.7e-25 87.9 0.5 7.4e-18 64.5 0.0 2.2 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 RNase_H PF00075.24 KNZ77590.1 - 2.2e-06 27.9 0.1 3.4e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 RNase H Voldacs PF03517.13 KNZ77591.1 - 1.2e-25 90.2 0.0 1.2e-25 90.2 0.0 2.7 2 1 1 3 3 3 1 Regulator of volume decrease after cellular swelling Pkinase PF00069.25 KNZ77592.1 - 4.6e-36 124.5 0.0 6.3e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77592.1 - 1.3e-33 116.4 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ77592.1 - 0.014 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Spore_YpjB PF09577.10 KNZ77592.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Kdo PF06293.14 KNZ77592.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_1 PF00018.28 KNZ77593.1 - 2e-13 49.7 0.1 2.9e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ77593.1 - 5.2e-13 48.6 0.1 7.6e-13 48.1 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ77593.1 - 5.8e-12 45.1 0.0 8.9e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pkinase_Tyr PF07714.17 KNZ77594.1 - 3.8e-20 72.3 0.0 6.5e-17 61.7 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ77594.1 - 2.8e-18 66.3 0.0 2e-16 60.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain DEAD PF00270.29 KNZ77596.1 - 5.8e-09 36.0 0.1 1e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KNZ77596.1 - 0.068 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.17 KNZ77597.1 - 9.7e-18 64.4 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ77597.1 - 4e-15 55.9 0.0 5.2e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KNZ77597.1 - 0.08 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 KNZ77597.1 - 0.13 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1349 PF07081.11 KNZ77598.1 - 1e-14 54.7 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) PLAC8 PF04749.17 KNZ77599.1 - 3.2e-23 82.6 9.5 4e-23 82.3 9.5 1.1 1 0 0 1 1 1 1 PLAC8 family AMP-binding PF00501.28 KNZ77600.1 - 1.5e-32 112.7 0.0 3.3e-32 111.6 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KNZ77600.1 - 3.3e-18 65.8 0.0 4.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KNZ77600.1 - 0.00021 20.8 0.0 0.00044 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KNZ77600.1 - 0.0015 18.9 0.1 0.0042 17.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PLAC8 PF04749.17 KNZ77602.1 - 8.4e-21 74.8 10.9 1.1e-20 74.5 10.9 1.2 1 0 0 1 1 1 1 PLAC8 family Ammonium_transp PF00909.21 KNZ77603.1 - 2.4e-117 392.0 29.7 2.8e-117 391.8 29.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.16 KNZ77606.1 - 1.8e-43 148.9 48.9 3.1e-43 148.1 48.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ77606.1 - 3.5e-16 59.1 12.0 3.5e-16 59.1 12.0 2.7 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KNZ77606.1 - 0.016 13.5 19.3 0.036 12.4 10.3 3.0 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3460 PF11943.8 KNZ77607.1 - 0.044 14.1 0.1 0.087 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Pkinase_Tyr PF07714.17 KNZ77608.1 - 2.1e-39 135.4 0.0 3.2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ77608.1 - 2.2e-37 128.9 0.0 3.1e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ77608.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chs7 PF12271.8 KNZ77609.1 - 1.7e-18 67.0 0.3 1.3e-11 44.5 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase export chaperone PIF1 PF05970.14 KNZ77611.1 - 9.8e-40 136.8 0.0 1.3e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ77611.1 - 0.00095 19.6 0.0 0.0065 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 KNZ77611.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ77611.1 - 0.0085 16.1 0.0 0.029 14.4 0.0 1.8 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ77611.1 - 0.036 13.8 0.2 0.08 12.7 0.2 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MitMem_reg PF13012.6 KNZ77611.1 - 0.056 13.9 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function DUF2791 PF10923.8 KNZ77611.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.14 KNZ77612.1 - 3.7e-33 115.2 0.0 4.2e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ77612.1 - 0.0036 17.0 0.1 0.0071 16.0 0.1 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal RVP_2 PF08284.11 KNZ77613.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease ATG13 PF10033.9 KNZ77614.1 - 3.6e-20 72.7 0.0 8.8e-20 71.4 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 Aldose_epim PF01263.20 KNZ77615.1 - 1.3e-60 205.2 0.7 1.8e-60 204.8 0.7 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Adeno_E3_CR2 PF02439.15 KNZ77616.1 - 2.7 7.8 7.7 1.6 8.5 1.8 3.5 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 Pkinase_Tyr PF07714.17 KNZ77617.1 - 5.8e-38 130.7 0.0 9.4e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ77617.1 - 2.9e-35 121.9 0.0 4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ77617.1 - 0.00082 18.8 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ77617.1 - 0.029 14.3 0.3 0.079 12.9 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ77617.1 - 0.098 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 KNZ77617.1 - 0.17 11.2 0.0 0.56 9.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Hva1_TUDOR PF11160.8 KNZ77618.1 - 3.7e-13 49.4 1.6 3.7e-13 49.4 1.6 3.2 4 0 0 4 4 4 1 Hypervirulence associated proteins TUDOR domain BTB PF00651.31 KNZ77619.1 - 0.057 13.6 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Molybdopterin_N PF18364.1 KNZ77619.1 - 0.17 11.9 0.2 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain Cu-oxidase PF00394.22 KNZ77620.1 - 2.2e-45 154.7 1.7 2.4e-41 141.5 0.6 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ77620.1 - 1.9e-39 134.5 1.0 1.2e-37 128.7 0.1 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ77620.1 - 4.1e-26 91.3 2.6 2.7e-25 88.7 0.4 2.7 3 0 0 3 3 3 1 Multicopper oxidase Sugar_tr PF00083.24 KNZ77621.1 - 1.8e-115 386.4 20.1 2.1e-115 386.2 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ77621.1 - 1.8e-24 86.4 25.6 1.8e-24 86.4 25.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Cu-oxidase PF00394.22 KNZ77623.1 - 7.6e-49 165.9 0.1 7.6e-45 152.9 0.0 3.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ77623.1 - 1.8e-35 121.5 0.1 8.8e-33 112.9 0.0 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ77623.1 - 3.9e-34 117.3 1.8 4.7e-28 97.6 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase GMC_oxred_N PF00732.19 KNZ77625.1 - 1.7e-33 116.3 0.0 2.2e-32 112.6 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ77625.1 - 1.5e-06 28.8 0.0 2.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ77625.1 - 6.1e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ77625.1 - 0.0001 22.0 0.3 0.0017 18.0 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ77625.1 - 0.00035 19.8 0.0 0.00072 18.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ77625.1 - 0.00051 19.4 0.0 0.0011 18.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ77625.1 - 0.0012 17.9 0.1 0.0018 17.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KNZ77625.1 - 0.0022 17.3 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 KNZ77625.1 - 0.0085 15.4 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.18 KNZ77625.1 - 0.042 12.4 0.0 0.061 11.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.14 KNZ77625.1 - 0.047 12.4 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KNZ77625.1 - 0.075 13.6 0.7 0.16 12.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNZ77625.1 - 0.22 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_2 PF00891.18 KNZ77626.1 - 3.3e-20 72.3 0.0 5.2e-18 65.1 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_12 PF08242.12 KNZ77626.1 - 0.001 19.7 0.0 0.026 15.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ77626.1 - 0.008 16.9 0.0 0.023 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KNZ77626.1 - 0.049 13.1 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Peptidase_S3 PF00944.19 KNZ77628.1 - 0.031 14.1 1.3 3.4 7.4 0.1 2.2 2 0 0 2 2 2 0 Alphavirus core protein FAD_binding_4 PF01565.23 KNZ77628.1 - 2.6 7.8 7.2 7.6 6.3 0.8 2.4 2 0 0 2 2 2 0 FAD binding domain Cu-oxidase PF00394.22 KNZ77629.1 - 3.3e-48 163.8 0.0 1.3e-44 152.1 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ77629.1 - 9.1e-37 125.7 0.0 1.3e-34 118.7 0.0 3.2 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ77629.1 - 5.4e-33 113.6 0.9 4.8e-28 97.6 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase HAD_2 PF13419.6 KNZ77630.1 - 1.8e-06 28.2 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ77630.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.26 KNZ77630.1 - 0.012 15.9 0.0 0.048 14.0 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Herpes_Helicase PF02689.14 KNZ77633.1 - 7.7e-07 27.5 0.0 8e-07 27.4 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ77633.1 - 0.0012 18.7 0.1 0.0034 17.2 0.1 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain ThylakoidFormat PF11264.8 KNZ77634.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein MFS_1 PF07690.16 KNZ77635.1 - 1.2e-34 119.8 45.0 1.2e-34 119.8 45.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nic96 PF04097.14 KNZ77637.1 - 8e-34 117.1 1.8 1e-33 116.8 1.8 1.0 1 0 0 1 1 1 1 Nup93/Nic96 MCM_N PF14551.6 KNZ77637.1 - 0.0079 16.8 0.1 5.9 7.5 0.0 2.3 2 0 0 2 2 2 2 MCM N-terminal domain SesA PF17107.5 KNZ77637.1 - 0.027 14.6 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Atg14 PF10186.9 KNZ77639.1 - 0.03 13.4 7.9 0.04 13.0 7.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 KNZ77639.1 - 0.06 12.6 5.8 0.073 12.3 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein PriC PF07445.12 KNZ77639.1 - 0.096 12.6 10.1 0.14 12.1 10.1 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC Seryl_tRNA_N PF02403.22 KNZ77639.1 - 0.12 12.6 8.6 1 9.6 8.6 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 KNZ77639.1 - 0.12 11.6 11.4 0.18 11.1 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 KNZ77639.1 - 0.96 9.8 9.1 2.4 8.6 2.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain Bud13 PF09736.9 KNZ77639.1 - 1.5 9.2 6.9 2 8.8 6.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex UPF0242 PF06785.11 KNZ77639.1 - 1.6 8.8 9.1 2.3 8.3 9.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 KNZ77639.1 - 2.8 6.7 11.1 5.3 5.8 11.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KNZ77639.1 - 2.9 7.1 11.8 4.2 6.6 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 KNZ77639.1 - 3.8 8.2 9.5 13 6.5 5.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Nic96 PF04097.14 KNZ77640.1 - 1.4e-36 126.2 1.3 1.6e-36 126.0 1.3 1.0 1 0 0 1 1 1 1 Nup93/Nic96 MCM_N PF14551.6 KNZ77640.1 - 0.014 16.0 0.1 3 8.5 0.0 2.3 2 0 0 2 2 2 0 MCM N-terminal domain SesA PF17107.5 KNZ77640.1 - 0.032 14.4 0.2 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases T2SSF PF00482.23 KNZ77640.1 - 0.086 12.8 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F PhoU PF01895.19 KNZ77640.1 - 0.98 9.9 4.2 45 4.6 0.1 3.2 2 2 1 3 3 3 0 PhoU domain Fes1 PF08609.10 KNZ77641.1 - 0.13 13.2 3.0 2.7 8.9 0.1 3.3 4 1 0 4 4 4 0 Nucleotide exchange factor Fes1 Helitron_like_N PF14214.6 KNZ77642.1 - 1.7e-17 64.3 0.1 2.1e-17 64.0 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ77642.1 - 0.15 12.0 0.1 0.18 11.8 0.1 1.1 1 0 0 1 1 1 0 Inovirus Gp2 PIF1 PF05970.14 KNZ77644.1 - 4.1e-08 32.8 0.0 4.1e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Herpes_LAMP2 PF06126.11 KNZ77645.1 - 0.027 13.1 0.0 0.028 13.0 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 DUF4413 PF14372.6 KNZ77645.1 - 0.059 13.8 0.3 1.2 9.5 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4413) GBP_repeat PF02526.14 KNZ77645.1 - 0.1 12.3 0.1 2.7 7.8 0.0 2.2 1 1 1 2 2 2 0 Glycophorin-binding protein Vps26 PF03643.15 KNZ77646.1 - 4.3e-12 45.6 0.0 4.6e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Pkinase_fungal PF17667.1 KNZ77649.1 - 1.8e-23 83.0 0.0 2.5e-16 59.5 0.0 3.0 1 1 0 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 KNZ77649.1 - 0.002 17.6 0.1 0.011 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77649.1 - 0.0051 16.1 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase M157 PF11624.8 KNZ77651.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 MHC class I-like protein M157 DUF3864 PF12980.7 KNZ77653.1 - 0.2 12.0 0.7 1.9 8.9 0.2 2.3 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) Aldedh PF00171.22 KNZ77655.1 - 7.4e-23 80.8 2.2 1e-17 63.8 0.4 2.9 1 1 1 2 2 2 2 Aldehyde dehydrogenase family EFG_C PF00679.24 KNZ77656.1 - 1.6e-30 104.9 0.1 3.1e-15 56.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ77656.1 - 6.2e-06 26.5 6.3 0.00031 21.1 1.5 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 RHSP PF07999.11 KNZ77656.1 - 0.0024 16.8 0.1 1.5 7.6 0.0 2.1 2 0 0 2 2 2 2 Retrotransposon hot spot protein Zn_protease PF05618.11 KNZ77656.1 - 0.045 13.6 0.0 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Putative ATP-dependant zinc protease EFG_II PF14492.6 KNZ77656.1 - 0.069 13.3 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Elongation Factor G, domain II TPR_12 PF13424.6 KNZ77657.1 - 1.7e-08 34.7 4.9 0.053 13.8 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ77657.1 - 1.7e-06 27.6 0.7 0.082 12.3 0.1 3.6 2 1 1 3 3 3 3 MalT-like TPR region TPR_16 PF13432.6 KNZ77657.1 - 2.6e-06 28.0 3.7 0.0044 17.6 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.6 KNZ77657.1 - 9.2e-05 22.7 0.0 0.00085 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ77657.1 - 0.00023 21.6 0.6 0.002 18.5 0.1 2.8 3 1 0 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 KNZ77657.1 - 0.00029 20.1 0.0 0.0021 17.3 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 KNZ77657.1 - 0.00052 19.8 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RPN7 PF10602.9 KNZ77657.1 - 0.0057 16.4 0.3 3.2 7.4 0.0 3.6 3 1 1 4 4 4 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 KNZ77657.1 - 0.008 16.2 16.3 6.6 7.1 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA PF00004.29 KNZ77657.1 - 0.011 16.1 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_19 PF14559.6 KNZ77657.1 - 0.021 15.3 7.8 1.3 9.6 0.3 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ77657.1 - 0.026 15.3 5.1 8 7.6 0.0 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 KNZ77657.1 - 0.069 13.2 0.5 0.37 10.9 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase zf-RVT PF13966.6 KNZ77658.1 - 0.00038 21.1 0.3 0.00063 20.4 0.3 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ77658.1 - 0.092 12.7 4.2 0.26 11.3 4.2 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain TerY_C PF15616.6 KNZ77658.1 - 0.096 12.8 0.9 0.32 11.1 0.1 1.9 1 1 1 2 2 2 0 TerY-C metal binding domain zf-FPG_IleRS PF06827.14 KNZ77658.1 - 0.41 10.5 4.9 3.1 7.8 4.9 2.3 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS zinc_ribbon_9 PF14369.6 KNZ77658.1 - 1.5 9.2 6.7 1.4 9.2 0.5 2.9 2 1 1 3 3 3 0 zinc-ribbon NB-ARC PF00931.22 KNZ77660.1 - 1.5e-05 24.3 0.0 3.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KNZ77660.1 - 0.00021 21.7 0.0 0.00091 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KNZ77660.1 - 0.0005 20.4 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ77660.1 - 0.0033 17.8 0.0 0.0091 16.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KNZ77660.1 - 0.0067 16.5 0.3 0.043 13.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 KNZ77660.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KNZ77660.1 - 0.023 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KNZ77660.1 - 0.029 14.3 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DUF3251 PF11622.8 KNZ77660.1 - 0.041 13.5 0.3 12 5.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3251) ABC_tran PF00005.27 KNZ77660.1 - 0.064 13.8 0.1 0.41 11.2 0.1 2.2 1 1 0 2 2 2 0 ABC transporter RuvB_N PF05496.12 KNZ77660.1 - 0.085 12.6 0.1 0.19 11.4 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KNZ77660.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Tudor_3 PF18115.1 KNZ77660.1 - 2.4 8.1 4.0 0.52 10.2 0.2 1.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain Aldedh PF00171.22 KNZ77661.1 - 1.7e-34 119.1 0.1 2.9e-27 95.3 0.0 3.0 2 1 1 3 3 3 3 Aldehyde dehydrogenase family Integrase_H2C2 PF17921.1 KNZ77663.1 - 2.9e-08 33.7 4.3 6.1e-08 32.7 4.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain TPR_MalT PF17874.1 KNZ77664.1 - 2.4e-08 33.7 2.9 0.0025 17.2 0.1 3.4 3 1 1 4 4 4 2 MalT-like TPR region TPR_2 PF07719.17 KNZ77664.1 - 1.8e-06 27.6 3.9 0.18 12.0 0.0 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 KNZ77664.1 - 6.3e-05 23.3 0.1 0.00045 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_12 PF13424.6 KNZ77664.1 - 9.2e-05 22.7 6.0 0.017 15.4 0.1 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ77664.1 - 0.00066 18.9 0.0 0.0017 17.6 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KNZ77664.1 - 0.00083 19.8 0.2 0.007 16.8 0.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.6 KNZ77664.1 - 0.0028 18.3 0.9 2 9.1 0.1 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat AAA PF00004.29 KNZ77664.1 - 0.0088 16.5 0.0 0.035 14.5 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNZ77664.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_14 PF13428.6 KNZ77664.1 - 0.082 13.8 0.0 32 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RsgA_GTPase PF03193.16 KNZ77664.1 - 0.1 12.5 0.3 0.4 10.6 0.0 2.1 3 0 0 3 3 3 0 RsgA GTPase RuvB_N PF05496.12 KNZ77664.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RT_RNaseH PF17917.1 KNZ77665.1 - 1.7e-07 31.5 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ77665.1 - 0.00047 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Herpes_UL47 PF03362.13 KNZ77666.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL47 protein Helitron_like_N PF14214.6 KNZ77668.1 - 8.6e-05 22.8 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus EPF PF17181.4 KNZ77668.1 - 0.0031 17.5 4.0 0.0061 16.5 4.0 1.6 1 1 0 1 1 1 1 Epidermal patterning factor proteins PIF1 PF05970.14 KNZ77669.1 - 2.6e-08 33.4 0.9 1.2e-05 24.7 0.3 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KNZ77669.1 - 0.0011 18.8 0.7 0.25 11.0 0.2 2.6 1 1 1 2 2 2 2 AAA domain DUF4632 PF15451.6 KNZ77671.1 - 0.047 13.8 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF3176 PF11374.8 KNZ77671.1 - 0.065 13.4 0.3 0.15 12.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) PetG PF02529.15 KNZ77671.1 - 0.99 9.3 4.3 2.2 8.2 4.3 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 FtsX PF02687.21 KNZ77671.1 - 2.6 8.6 7.3 2.3 8.8 2.0 3.0 2 1 0 2 2 2 0 FtsX-like permease family ADH_zinc_N_2 PF13602.6 KNZ77672.1 - 0.092 13.8 0.2 1.2 10.2 0.0 2.7 2 1 0 2 2 2 0 Zinc-binding dehydrogenase ATP_bind_3 PF01171.20 KNZ77673.1 - 1.6e-18 67.1 0.0 2.4e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 KNZ77673.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF4428 PF14471.6 KNZ77673.1 - 0.022 14.7 0.4 0.049 13.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Sugar_tr PF00083.24 KNZ77674.1 - 1.3e-52 179.3 16.9 2.4e-31 109.1 4.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ77674.1 - 2.6e-19 69.3 27.2 2.6e-19 69.3 27.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NPR3 PF03666.13 KNZ77675.1 - 7 5.3 8.8 11 4.7 8.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_2 PF00891.18 KNZ77676.1 - 1.8e-10 40.4 0.0 7.1e-09 35.3 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain RNase_H PF00075.24 KNZ77677.1 - 3.7e-05 23.9 0.0 7.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ77677.1 - 0.00072 20.2 1.8 0.0052 17.5 1.8 2.2 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ77677.1 - 0.26 11.3 3.1 0.13 12.2 0.7 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Exo_endo_phos_2 PF14529.6 KNZ77678.1 - 6.8e-08 32.4 0.1 1.5e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 KNZ77678.1 - 0.018 14.5 0.8 0.055 13.0 0.6 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SprA-related PF12118.8 KNZ77679.1 - 0.064 12.4 0.2 0.085 12.0 0.2 1.2 1 0 0 1 1 1 0 SprA-related family zf-RVT PF13966.6 KNZ77681.1 - 0.0066 17.1 0.8 0.014 16.1 0.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Cyclin_N PF00134.23 KNZ77683.1 - 2e-12 46.9 0.0 3.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KNZ77683.1 - 1e-11 45.5 0.0 9.7e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Cyclin Mito_carr PF00153.27 KNZ77684.1 - 1.5e-52 175.4 1.4 7.8e-19 67.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S9_N PF02897.15 KNZ77685.1 - 1.1e-85 288.0 8.0 1.4e-85 287.6 8.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 KNZ77685.1 - 2.8e-46 157.7 0.7 5.8e-31 107.6 0.2 2.6 1 1 1 2 2 2 2 Prolyl oligopeptidase family MafB19-deam PF14437.6 KNZ77686.1 - 6.9e-23 80.9 0.0 1.4e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 KNZ77686.1 - 4.7e-22 77.8 0.1 7.2e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 KNZ77686.1 - 0.00029 20.9 1.5 0.014 15.4 1.5 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 KNZ77686.1 - 0.00075 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 KNZ77686.1 - 0.0048 17.0 0.0 0.0072 16.4 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC1 PF18769.1 KNZ77686.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 APOBEC1 APOBEC3 PF18771.1 KNZ77686.1 - 0.0067 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 APOBEC4_like PF18774.1 KNZ77686.1 - 0.0085 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 KNZ77686.1 - 0.0098 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 KNZ77686.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD2 PF18782.1 KNZ77686.1 - 0.075 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APH PF01636.23 KNZ77687.1 - 7.2e-08 32.6 0.0 3.3e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 KNZ77688.1 - 2.6e-27 95.9 2.2 4.5e-27 95.1 2.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KNZ77688.1 - 2.6e-17 62.7 0.0 1.1e-16 60.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KNZ77688.1 - 2.4e-15 56.5 0.6 4.5e-15 55.6 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KNZ77688.1 - 6e-12 46.2 0.0 1.9e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KNZ77688.1 - 2.4e-05 24.6 0.5 5.8e-05 23.4 0.3 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain PIF1 PF05970.14 KNZ77689.1 - 6.2e-14 51.9 0.1 8e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase ATP-synt_C PF00137.21 KNZ77690.1 - 9.2e-35 118.8 33.7 6.2e-22 77.7 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C EHN PF06441.12 KNZ77691.1 - 6.5e-31 106.9 0.0 1.2e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KNZ77691.1 - 1.7e-14 54.1 0.0 1.4e-13 51.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ77691.1 - 0.00016 22.4 2.8 0.0029 18.2 2.8 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family SNF2_N PF00176.23 KNZ77692.1 - 6.8e-53 179.6 0.4 1.8e-51 174.9 0.3 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ77692.1 - 6.2e-15 55.5 0.0 1.5e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KNZ77692.1 - 4.2e-06 26.5 5.8 4.2e-06 26.5 5.8 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ77692.1 - 4.3e-06 27.0 5.9 4.3e-06 27.0 5.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ77692.1 - 4.6e-06 26.4 4.9 4.6e-06 26.4 4.9 2.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ77692.1 - 3e-05 23.9 1.7 3e-05 23.9 1.7 2.6 2 1 0 2 2 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 KNZ77692.1 - 0.00013 22.2 3.1 0.00037 20.7 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KNZ77692.1 - 0.0013 18.5 3.7 0.0032 17.3 3.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 KNZ77692.1 - 0.0016 18.3 4.4 0.0016 18.3 4.4 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNZ77692.1 - 0.0019 18.3 4.3 0.0019 18.3 4.3 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KNZ77692.1 - 0.0063 16.5 0.6 0.018 15.1 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD PF00270.29 KNZ77692.1 - 0.0068 16.2 0.1 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KNZ77692.1 - 0.0088 16.1 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.27 KNZ77693.1 - 2.6e-48 161.9 5.2 4.5e-19 68.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ZoocinA_TRD PF16775.5 KNZ77693.1 - 0.14 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme Spt4 PF06093.13 KNZ77694.1 - 1.6e-30 105.0 0.2 2e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Lipase_3 PF01764.25 KNZ77695.1 - 1.4e-16 60.7 0.0 3.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KNZ77695.1 - 0.039 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 p450 PF00067.22 KNZ77696.1 - 3.9e-59 200.6 0.0 9e-59 199.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M24 PF00557.24 KNZ77697.1 - 9.7e-56 188.8 0.0 1.3e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KNZ77697.1 - 5.7e-40 135.9 0.1 1.1e-39 135.0 0.1 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Chromo PF00385.24 KNZ77698.1 - 0.02 14.8 0.1 0.036 14.0 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF2315 PF10231.9 KNZ77698.1 - 0.12 12.5 0.1 2.2 8.4 0.0 2.1 1 1 1 2 2 2 0 Apoptogenic protein 1 WW PF00397.26 KNZ77702.1 - 5e-08 32.9 8.4 1e-07 31.9 8.4 1.6 1 0 0 1 1 1 1 WW domain HMG_box PF00505.19 KNZ77703.1 - 3.5e-17 62.6 4.0 3.5e-17 62.6 4.0 2.1 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ77703.1 - 7.4e-11 42.5 3.7 7.4e-11 42.5 3.7 2.1 2 1 0 2 2 2 1 HMG-box domain CHDNT PF08073.12 KNZ77703.1 - 0.0003 20.7 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain Med26 PF08711.11 KNZ77704.1 - 8.4e-10 38.5 0.5 1.9e-09 37.4 0.5 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain FXMRP1_C_core PF12235.8 KNZ77704.1 - 0.012 16.2 5.5 0.012 16.2 5.5 2.8 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal LIM_bind PF01803.16 KNZ77706.1 - 5.5e-60 202.9 0.1 1.8e-59 201.2 0.0 2.0 2 0 0 2 2 2 1 LIM-domain binding protein uDENN PF03456.18 KNZ77707.1 - 0.023 15.5 0.0 11 6.8 0.0 2.2 2 0 0 2 2 2 0 uDENN domain Smg8_Smg9 PF10220.9 KNZ77707.1 - 0.12 10.7 0.0 7 4.8 0.0 2.0 2 0 0 2 2 2 0 Smg8_Smg9 Unstab_antitox PF09720.10 KNZ77707.1 - 1.2 9.2 5.4 6.1 7.0 0.6 2.3 2 0 0 2 2 2 0 Putative addiction module component OTT_1508_deam PF14441.6 KNZ77708.1 - 3.8e-07 30.0 0.0 1.1e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 OTT_1508-like deaminase Smg8_Smg9 PF10220.9 KNZ77708.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 OTT_1508_deam PF14441.6 KNZ77709.1 - 2.9e-08 33.6 0.3 6.3e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase CDC48_2 PF02933.17 KNZ77709.1 - 0.032 14.0 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 OTT_1508_deam PF14441.6 KNZ77710.1 - 5e-07 29.6 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Smg8_Smg9 PF10220.9 KNZ77710.1 - 0.11 10.7 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Ribosomal_S4 PF00163.19 KNZ77711.1 - 1.5e-11 45.0 0.5 2.1e-11 44.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 KNZ77711.1 - 1.6e-11 43.7 0.0 2.7e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 S4 domain Herpes_LAMP2 PF06126.11 KNZ77711.1 - 0.056 12.1 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 p450 PF00067.22 KNZ77712.1 - 9.8e-58 196.0 0.0 5.5e-56 190.2 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 KNZ77713.1 - 0.00016 21.1 0.0 0.00033 20.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SAA PF00277.18 KNZ77713.1 - 0.071 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Serum amyloid A protein Amino_oxidase PF01593.24 KNZ77713.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Kinesin PF00225.23 KNZ77714.1 - 2.3e-103 345.6 0.0 3.5e-103 345.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin_assoc PF16183.5 KNZ77714.1 - 4.5e-41 141.0 6.0 1.6e-31 109.9 1.9 2.7 1 1 1 2 2 2 2 Kinesin-associated DUF3694 PF12473.8 KNZ77714.1 - 2.7e-38 132.0 0.0 7.6e-38 130.6 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Microtub_bd PF16796.5 KNZ77714.1 - 3.2e-16 59.6 0.0 9.2e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KNZ77714.1 - 5.3e-11 43.0 0.0 2.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 PH domain FHA PF00498.26 KNZ77714.1 - 9.1e-06 25.9 0.0 3.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 KNZ77714.1 - 1.8e-05 25.1 0.7 1.8e-05 25.1 0.7 2.0 2 0 0 2 2 2 1 Kinesin protein 1B EAP30 PF04157.16 KNZ77714.1 - 0.017 14.4 1.2 0.036 13.4 0.4 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family zf-C4H2 PF10146.9 KNZ77714.1 - 0.24 11.7 6.2 1 9.6 0.0 2.8 2 0 0 2 2 2 0 Zinc finger-containing protein CMAS PF02353.20 KNZ77715.1 - 1.1e-57 195.4 0.0 1.5e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KNZ77715.1 - 3.9e-08 33.9 0.0 8.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ77715.1 - 2.2e-06 28.2 0.0 4.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ77715.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ77715.1 - 0.0026 17.6 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ77715.1 - 0.011 16.4 0.0 0.024 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 KNZ77715.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.6 1 1 1 2 2 2 0 Histone methylation protein DOT1 Microtub_bd PF16796.5 KNZ77715.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding SAC3 PF12209.8 KNZ77715.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain MTS PF05175.14 KNZ77715.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Arf PF00025.21 KNZ77716.1 - 1.1e-70 236.6 0.1 1.3e-70 236.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KNZ77716.1 - 3.2e-14 52.8 0.8 3.4e-08 33.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KNZ77716.1 - 1.2e-11 44.8 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 KNZ77716.1 - 1.9e-09 37.2 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KNZ77716.1 - 2.4e-09 37.0 0.0 3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 KNZ77716.1 - 6.6e-09 35.5 0.0 9.5e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KNZ77716.1 - 8.6e-07 29.0 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KNZ77716.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KNZ77716.1 - 0.062 12.9 0.0 0.76 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KNZ77716.1 - 0.071 13.0 0.2 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 KNZ77716.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.18 KNZ77716.1 - 0.12 11.9 0.1 0.25 10.8 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AA_permease_2 PF13520.6 KNZ77717.1 - 1.5e-41 142.6 54.8 2e-41 142.2 54.8 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU PF00009.27 KNZ77717.1 - 1.2e-34 119.5 0.0 4.8e-34 117.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KNZ77717.1 - 1.2e-19 70.3 0.0 3.2e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 AA_permease PF00324.21 KNZ77717.1 - 3.2e-19 68.9 45.6 4.7e-19 68.3 45.6 1.1 1 0 0 1 1 1 1 Amino acid permease GTP_EFTU_D2 PF03144.25 KNZ77717.1 - 2.9e-14 53.2 5.1 6.3e-10 39.3 0.1 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ77717.1 - 1.9e-06 27.9 0.1 2e-05 24.6 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KNZ77717.1 - 7e-06 25.9 0.1 1.9e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 KNZ77717.1 - 9.1e-05 22.7 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KNZ77717.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ras PF00071.22 KNZ77717.1 - 0.077 12.6 0.0 0.33 10.6 0.0 2.2 1 1 0 1 1 1 0 Ras family AAA_22 PF13401.6 KNZ77717.1 - 0.2 11.9 0.5 1.8 8.8 0.5 2.4 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 KNZ77718.1 - 2e-20 73.3 0.0 9.9e-13 48.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77718.1 - 4.6e-07 29.4 0.0 0.002 17.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ77718.1 - 0.051 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ICMT PF04140.14 KNZ77719.1 - 7.6e-13 48.7 1.4 3.3e-12 46.6 0.4 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KNZ77719.1 - 2.5e-10 40.7 1.7 1.3e-09 38.3 1.7 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KNZ77719.1 - 2.1e-06 26.8 0.1 3.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Acyl-CoA_dh_1 PF00441.24 KNZ77720.1 - 1.2e-44 152.1 1.1 1.8e-44 151.5 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KNZ77720.1 - 1.3e-30 106.4 0.8 7.1e-30 104.0 0.0 2.3 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KNZ77720.1 - 8.3e-23 80.4 0.0 1.5e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KNZ77720.1 - 1.5e-20 73.8 0.1 2.4e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ric8 PF10165.9 KNZ77721.1 - 1.7e-124 416.4 0.0 2e-124 416.1 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.9 KNZ77722.1 - 3.5e-22 78.6 0.2 4e-22 78.4 0.2 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.6 KNZ77722.1 - 0.012 15.9 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 PIN domain KIAA1430 PF13879.6 KNZ77722.1 - 0.077 13.8 0.2 0.1 13.3 0.2 1.2 1 0 0 1 1 1 0 KIAA1430 homologue RT_RNaseH PF17917.1 KNZ77723.1 - 3.9e-08 33.5 0.0 8.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ77723.1 - 0.0002 21.3 0.0 0.00062 19.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase FA_desaturase PF00487.24 KNZ77724.1 - 1 9.1 7.1 2.2 8.0 5.2 2.3 2 0 0 2 2 2 0 Fatty acid desaturase SCIMP PF15050.6 KNZ77724.1 - 6.4 7.2 8.8 23 5.4 0.0 2.6 2 0 0 2 2 2 0 SCIMP protein SAE2 PF08573.10 KNZ77725.1 - 2.4e-24 86.6 2.0 2.4e-24 86.6 2.0 4.2 4 1 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus CorA PF01544.18 KNZ77725.1 - 3.5 6.8 8.3 13 5.0 8.3 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein SOAR PF16533.5 KNZ77725.1 - 8.5 6.4 9.7 5.5 7.0 0.1 3.1 3 0 0 3 3 3 0 STIM1 Orai1-activating region DUF2235 PF09994.9 KNZ77730.1 - 8e-90 301.1 0.0 1.2e-88 297.3 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KNZ77730.1 - 0.033 14.1 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GPI-anchored PF10342.9 KNZ77732.1 - 0.0014 19.3 2.6 0.002 18.9 1.3 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KNZ77732.1 - 0.0017 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 KNZ77732.1 - 0.074 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Helitron_like_N PF14214.6 KNZ77733.1 - 1.2e-64 218.1 0.1 1.9e-64 217.4 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ77733.1 - 0.045 12.9 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) APH PF01636.23 KNZ77735.1 - 1.4e-10 41.5 0.7 1.6e-10 41.3 0.7 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ77735.1 - 0.00065 19.3 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ77735.1 - 0.038 13.6 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Thiolase_N PF00108.23 KNZ77736.1 - 3.1e-59 200.5 1.8 4.8e-59 199.8 1.8 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNZ77736.1 - 2.9e-30 104.4 0.8 5.5e-22 77.7 0.0 2.7 3 0 0 3 3 3 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KNZ77736.1 - 0.00033 20.3 0.4 0.0033 17.0 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PAP1 PF08601.10 KNZ77738.1 - 1.3 8.7 4.7 1.9 8.1 4.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 HAUS2 PF15003.6 KNZ77739.1 - 0.017 14.9 0.2 0.017 14.9 0.2 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 HAD_2 PF13419.6 KNZ77741.1 - 4.4e-08 33.4 0.0 8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ77741.1 - 0.0013 19.1 0.0 0.0036 17.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ77741.1 - 0.0019 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like GFA PF04828.14 KNZ77742.1 - 8.9e-07 29.2 1.1 1e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme AMP-binding PF00501.28 KNZ77743.1 - 1.8e-76 257.5 0.0 4.2e-76 256.2 0.0 1.5 1 1 1 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ77743.1 - 1.9e-11 44.8 0.2 3.4e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RMI1_N PF08585.12 KNZ77743.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein CENP-X PF09415.10 KNZ77744.1 - 0.011 16.0 0.2 0.036 14.4 0.1 1.8 2 0 0 2 2 2 0 CENP-S associating Centromere protein X ADH_zinc_N PF00107.26 KNZ77745.1 - 1.4e-28 99.5 0.1 2e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ77745.1 - 9.5e-13 49.3 0.0 1.5e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ77745.1 - 2.4e-07 30.6 0.0 4.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 KNZ77745.1 - 0.098 12.1 0.9 0.15 11.5 0.9 1.3 1 0 0 1 1 1 0 short chain dehydrogenase CoaE PF01121.20 KNZ77746.1 - 5.3e-66 221.7 0.0 6.5e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 KNZ77746.1 - 4.2e-05 24.1 0.0 0.00011 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KNZ77746.1 - 0.0073 16.1 0.4 1.4 8.6 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family Pox_mRNA-cap PF03341.13 KNZ77746.1 - 0.017 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus mRNA capping enzyme, small subunit DUF913 PF06025.12 KNZ77747.1 - 4.4e-98 328.6 11.4 3.1e-97 325.9 0.0 4.6 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) HECT PF00632.25 KNZ77747.1 - 1.6e-91 307.0 0.0 2.7e-91 306.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 KNZ77747.1 - 1.5e-81 274.6 2.5 5e-81 272.9 2.5 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) UBM PF14377.6 KNZ77747.1 - 1.9e-17 62.1 15.5 1.6e-11 43.2 0.8 3.2 3 0 0 3 3 3 2 Ubiquitin binding region UBA PF00627.31 KNZ77747.1 - 9.7e-14 50.9 0.5 5.7e-12 45.3 0.1 2.7 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.16 KNZ77747.1 - 0.012 15.3 0.0 0.096 12.4 0.0 2.5 2 0 0 2 2 2 0 CUE domain DUF3361 PF11841.8 KNZ77747.1 - 0.015 15.2 1.4 29 4.6 0.0 4.9 5 1 0 5 5 5 0 Domain of unknown function (DUF3361) FA_hydroxylase PF04116.13 KNZ77748.1 - 1.8e-23 83.3 21.8 1.8e-23 83.3 21.8 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PC4 PF02229.16 KNZ77749.1 - 2.4e-21 75.1 0.1 3.4e-21 74.6 0.1 1.2 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ABC1 PF03109.16 KNZ77750.1 - 6.6e-34 116.6 0.0 1.1e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 KNZ77750.1 - 0.0001 22.0 0.1 0.00074 19.2 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KNZ77750.1 - 0.084 12.2 0.0 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain DUF3467 PF11950.8 KNZ77751.1 - 0.074 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) SporV_AA PF12164.8 KNZ77751.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 2 0 0 2 2 2 0 Stage V sporulation protein AA APG6 PF04111.12 KNZ77752.1 - 8.4e-55 185.5 0.1 8.3e-41 139.9 0.0 3.2 1 1 1 2 2 2 2 Apg6 BARA domain APG6_N PF17675.1 KNZ77752.1 - 1.6e-27 96.7 22.2 2.2e-27 96.2 22.2 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region FtsL PF04999.13 KNZ77752.1 - 0.23 11.5 8.2 0.29 11.2 6.6 1.9 2 0 0 2 2 2 0 Cell division protein FtsL V_ATPase_I PF01496.19 KNZ77752.1 - 0.9 7.4 4.3 1.2 7.0 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 KNZ77752.1 - 1.1 7.8 8.0 1.5 7.3 8.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DDE_1 PF03184.19 KNZ77753.1 - 6.8e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease CNOT1_CAF1_bind PF16415.5 KNZ77753.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CDI PF02234.19 KNZ77755.1 - 1.1 9.5 6.5 0.64 10.2 2.1 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor zf-CCHC PF00098.23 KNZ77757.1 - 0.011 15.8 0.8 0.02 14.9 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3895 PF13034.6 KNZ77757.1 - 0.073 13.1 0.1 0.38 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3895) gag-asp_proteas PF13975.6 KNZ77759.1 - 4.8e-07 30.2 0.0 2.1e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ77759.1 - 7.4e-06 26.5 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ77759.1 - 0.02 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF4536 PF15055.6 KNZ77760.1 - 7.2e-08 32.5 2.2 7.2e-08 32.5 2.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) ECH_1 PF00378.20 KNZ77761.1 - 1.1e-85 287.0 0.2 1.2e-85 286.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KNZ77761.1 - 4.7e-36 124.9 0.1 1.4e-32 113.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KNZ77761.1 - 0.051 13.5 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S49 YCII PF03795.14 KNZ77762.1 - 8.8e-06 26.0 0.0 1.1e-05 25.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.14 KNZ77763.1 - 6.5e-07 29.7 0.0 8.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain zf-HIT PF04438.16 KNZ77764.1 - 0.21 11.5 1.8 0.88 9.5 0.3 2.1 2 0 0 2 2 2 0 HIT zinc finger Antistasin PF02822.14 KNZ77764.1 - 2 9.1 5.8 0.94 10.2 0.3 2.2 2 0 0 2 2 2 0 Antistasin family Med12 PF09497.10 KNZ77765.1 - 1.2e-26 92.8 0.1 3.9e-26 91.1 0.1 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 KNZ77765.1 - 0.009 14.9 0.1 0.045 12.6 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DASH_Dad2 PF08654.10 KNZ77766.1 - 2.6e-09 37.4 0.0 3.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 RSN1_7TM PF02714.15 KNZ77767.1 - 2.5e-58 197.6 22.8 8.4e-58 195.8 15.1 3.4 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KNZ77767.1 - 1.6e-31 109.9 0.8 2.5e-31 109.3 0.0 1.7 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KNZ77767.1 - 1.6e-28 99.5 7.5 9.8e-16 57.9 2.1 3.3 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KNZ77767.1 - 3.7e-11 43.0 0.1 1.8e-10 40.8 0.1 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DoxX_3 PF13781.6 KNZ77767.1 - 0.017 15.7 1.6 0.065 13.9 1.6 2.0 1 0 0 1 1 1 0 DoxX-like family HEAT PF02985.22 KNZ77768.1 - 1.5e-06 28.0 0.1 1.7 9.1 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat Pkinase PF00069.25 KNZ77768.1 - 3.1e-06 26.8 0.0 5.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 KNZ77768.1 - 0.00034 20.7 0.2 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 KNZ77768.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 KNZ77768.1 - 0.0023 18.3 0.0 3.3 8.2 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 KNZ77768.1 - 0.012 16.1 0.1 2.5 8.7 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat Caudal_act PF04731.12 KNZ77768.1 - 0.091 13.1 0.3 0.79 10.1 0.3 2.3 2 0 0 2 2 2 0 Caudal like protein activation region Vac14_Fab1_bd PF12755.7 KNZ77768.1 - 0.2 12.3 0.1 15 6.2 0.0 2.6 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Med14 PF08638.11 KNZ77769.1 - 3.2e-69 232.2 0.3 6.9e-69 231.1 0.3 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 Acetyltransf_1 PF00583.25 KNZ77771.1 - 1.4e-11 44.7 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GIY-YIG PF01541.24 KNZ77771.1 - 2.7e-11 43.6 0.0 5.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain Acetyltransf_7 PF13508.7 KNZ77771.1 - 6e-07 29.8 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ77771.1 - 1e-05 25.5 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KNZ77771.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KNZ77771.1 - 0.0016 18.3 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PEPCK_ATP PF01293.20 KNZ77772.1 - 9.5e-218 723.5 0.0 1.1e-217 723.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DGOK PF05035.12 KNZ77772.1 - 0.036 13.0 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase AAA_29 PF13555.6 KNZ77772.1 - 0.085 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KNZ77772.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dimer_Tnp_hAT PF05699.14 KNZ77773.1 - 6.5e-20 70.7 0.0 7.9e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PHD PF00628.29 KNZ77774.1 - 1.3e-08 34.6 4.2 7.6e-07 28.9 1.6 2.3 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 KNZ77774.1 - 0.0036 16.9 1.1 0.0036 16.9 1.1 1.8 1 1 1 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 KNZ77774.1 - 0.0065 16.3 3.9 0.0065 16.3 3.9 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 KNZ77774.1 - 0.033 14.1 2.5 0.033 14.1 2.5 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KNZ77774.1 - 0.038 13.5 1.0 0.038 13.5 1.0 2.6 3 0 0 3 3 3 0 PHD-finger PHD_4 PF16866.5 KNZ77774.1 - 0.14 12.3 4.3 0.38 10.9 4.3 1.8 1 1 0 1 1 1 0 PHD-finger C1_2 PF03107.16 KNZ77774.1 - 0.46 10.8 6.8 0.68 10.3 4.6 2.1 2 0 0 2 2 2 0 C1 domain Insulin_TMD PF17870.1 KNZ77775.1 - 0.37 10.9 2.8 14 5.9 0.0 3.7 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Fungus-induced PF10917.8 KNZ77775.1 - 4.3 7.7 6.1 16 5.9 0.2 3.4 3 0 0 3 3 3 0 Fungus-induced protein Peroxidase_ext PF11895.8 KNZ77776.1 - 6.2e-28 96.6 1.4 1.3e-27 95.6 1.4 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region peroxidase PF00141.23 KNZ77776.1 - 3.8e-27 95.5 0.0 5.4e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DNA_primase_S PF01896.19 KNZ77777.1 - 2e-42 145.2 0.1 2.6e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit TetR_C_20 PF17925.1 KNZ77778.1 - 0.11 12.8 0.6 4.5 7.6 0.0 3.1 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Adaptin_N PF01602.20 KNZ77779.1 - 8.7e-21 74.1 1.3 2.8e-19 69.1 1.0 2.7 2 1 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 KNZ77779.1 - 0.018 15.3 1.8 16 6.1 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 KNZ77779.1 - 0.029 14.4 2.5 0.58 10.2 0.1 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ77779.1 - 0.077 13.4 5.3 0.15 12.5 0.2 3.8 5 0 0 5 5 5 0 HEAT repeats RabGAP-TBC PF00566.18 KNZ77780.1 - 1.5e-39 135.9 0.0 2.1e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain bZIP_1 PF00170.21 KNZ77781.1 - 0.00021 21.3 2.3 0.00045 20.3 2.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 KNZ77781.1 - 0.016 15.1 0.8 0.019 14.8 0.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF1192 PF06698.11 KNZ77781.1 - 0.037 14.1 1.5 0.1 12.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MHC2-interact PF09307.10 KNZ77781.1 - 0.08 12.9 0.5 3.1 7.8 0.0 2.3 2 0 0 2 2 2 0 CLIP, MHC2 interacting TSC22 PF01166.18 KNZ77781.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.15 KNZ77781.1 - 0.45 10.6 7.7 0.087 12.9 3.9 1.8 2 0 0 2 2 2 0 Basic region leucine zipper IU_nuc_hydro PF01156.19 KNZ77782.1 - 3.5e-33 115.5 0.0 4.5e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase WD40 PF00400.32 KNZ77783.1 - 1.3e-43 146.1 23.5 2.4e-08 34.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ77783.1 - 1.3e-09 38.2 0.8 0.051 13.9 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ77783.1 - 0.00047 20.0 0.2 2.9 7.9 0.0 4.1 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KNZ77783.1 - 0.0024 16.6 8.3 0.18 10.4 0.3 4.4 2 1 2 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 KNZ77783.1 - 0.0026 17.7 0.2 0.54 10.1 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Got1 PF04178.12 KNZ77785.1 - 7.1e-19 68.3 14.0 9e-19 68.0 14.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family U3_assoc_6 PF08640.11 KNZ77787.1 - 7.8e-28 96.4 5.8 6.3e-26 90.3 3.1 3.0 2 1 1 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 KNZ77787.1 - 8.7e-06 26.1 9.5 0.032 15.1 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 KNZ77787.1 - 5.6e-05 22.4 0.5 0.002 17.3 0.1 2.7 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 KNZ77787.1 - 0.001 18.3 7.5 0.079 12.2 2.5 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat Suf PF05843.14 KNZ77787.1 - 0.066 13.2 0.1 0.41 10.6 0.0 2.2 1 1 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_19 PF14559.6 KNZ77787.1 - 0.096 13.2 0.5 3.8 8.1 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 KNZ77788.1 - 7.9e-35 120.5 0.0 1.8e-33 116.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77788.1 - 2.6e-19 69.5 0.0 4.9e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ77788.1 - 0.16 11.3 0.0 0.43 9.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Cyclin PF08613.11 KNZ77789.1 - 3.4e-18 66.5 2.2 7.3e-18 65.4 1.2 1.8 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 KNZ77789.1 - 0.036 13.8 1.0 0.066 13.0 1.0 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain Ribosomal_L11_N PF03946.14 KNZ77790.1 - 1.1e-23 82.8 0.1 1.8e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KNZ77790.1 - 6.4e-17 61.8 0.2 1.2e-16 61.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RNase_H PF00075.24 KNZ77791.1 - 1.4e-10 41.5 0.1 2.9e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KNZ77791.1 - 0.01 15.6 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like RT_RNaseH PF17917.1 KNZ77795.1 - 1.3e-08 35.1 0.0 2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ77795.1 - 5.9e-06 26.3 0.0 9.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF3945 PF13101.6 KNZ77796.1 - 0.13 12.0 0.1 14 5.5 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3945) p450 PF00067.22 KNZ77797.1 - 5.9e-36 124.2 0.0 1.5e-35 122.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KNZ77800.1 - 2.2e-33 115.7 0.0 8e-23 80.9 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 KNZ77801.1 - 1.7e-67 228.2 0.0 2.1e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CobT PF06213.12 KNZ77802.1 - 0.012 15.0 0.2 0.018 14.4 0.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT rve_3 PF13683.6 KNZ77802.1 - 0.12 12.2 0.1 0.98 9.3 0.0 2.5 3 0 0 3 3 3 0 Integrase core domain RT_RNaseH PF17917.1 KNZ77803.1 - 1.4e-08 35.0 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ77803.1 - 0.00051 20.0 0.0 0.00096 19.2 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Phage_holin_3_6 PF07332.11 KNZ77804.1 - 8.8 6.4 8.0 2 8.5 0.6 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Retrotran_gag_2 PF14223.6 KNZ77805.1 - 0.096 12.3 0.1 0.58 9.8 0.1 1.9 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type Trp_halogenase PF04820.14 KNZ77806.1 - 5.2e-25 88.2 0.0 4e-18 65.5 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KNZ77806.1 - 0.028 13.7 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Dus PF01207.17 KNZ77807.1 - 5.3e-25 88.2 0.0 1e-24 87.2 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) RVP_2 PF08284.11 KNZ77808.1 - 0.14 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease TMEM125 PF15109.6 KNZ77810.1 - 0.24 11.8 4.0 0.49 10.7 4.0 1.6 1 0 0 1 1 1 0 TMEM125 protein family Abhydrolase_2 PF02230.16 KNZ77811.1 - 6e-26 91.6 0.0 7.8e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 KNZ77811.1 - 0.021 14.5 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 KNZ77811.1 - 0.025 15.2 0.3 0.08 13.5 0.3 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KNZ77811.1 - 0.032 13.7 0.0 1.2 8.6 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family YycC PF14174.6 KNZ77811.1 - 0.18 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein Abhydrolase_9_N PF15420.6 KNZ77813.1 - 0.051 13.6 0.4 0.051 13.6 0.4 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus RNase_H PF00075.24 KNZ77814.1 - 1.9e-05 24.9 0.2 4.3e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ77815.1 - 0.0028 18.3 1.2 0.0039 17.9 1.2 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Zn-ribbon_8 PF09723.10 KNZ77815.1 - 0.044 13.9 1.7 0.049 13.8 0.0 1.9 2 1 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 KNZ77815.1 - 0.055 13.4 4.1 0.12 12.4 4.1 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 KNZ77815.1 - 0.21 11.9 0.5 0.21 11.9 0.5 2.3 2 1 1 3 3 3 0 zinc-ribbon APH PF01636.23 KNZ77818.1 - 1.2e-10 41.7 0.0 1.9e-10 41.1 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ77818.1 - 4.2e-06 26.5 0.0 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ77818.1 - 0.0088 15.7 0.0 0.12 11.9 0.0 2.2 2 1 0 2 2 2 1 RIO1 family Pkinase PF00069.25 KNZ77818.1 - 0.018 14.4 0.0 5.1 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain DUF3716 PF12511.8 KNZ77822.1 - 0.043 13.8 0.4 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Asp_protease_2 PF13650.6 KNZ77823.1 - 0.00019 22.0 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ77823.1 - 0.00088 19.8 0.0 0.0019 18.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Exo_endo_phos_2 PF14529.6 KNZ77827.1 - 1.5e-08 34.4 5.4 3.1e-08 33.5 3.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Acetyltransf_1 PF00583.25 KNZ77828.1 - 1.9e-10 41.0 0.0 2.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ77828.1 - 6.1e-09 35.9 0.0 8.3e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ77828.1 - 1.6e-08 34.8 0.1 2.4e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ77828.1 - 0.088 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Aminotran_1_2 PF00155.21 KNZ77829.1 - 3.5e-55 187.7 0.0 4.4e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_His PF13393.6 KNZ77830.1 - 5.7e-41 140.8 2.7 3.6e-37 128.3 0.0 2.8 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KNZ77830.1 - 1.2e-09 38.1 0.2 2.6e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 KNZ77830.1 - 9.1e-07 28.6 0.2 1.6e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 KNZ77830.1 - 5.1e-06 26.6 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 KNZ77830.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) TBCA PF02970.16 KNZ77830.1 - 0.098 13.0 0.3 0.36 11.2 0.3 2.0 1 0 0 1 1 1 0 Tubulin binding cofactor A Cpn10 PF00166.21 KNZ77831.1 - 2.4e-23 82.0 0.0 2.8e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn60_TCP1 PF00118.24 KNZ77832.1 - 1.2e-79 268.2 4.1 2e-79 267.5 4.1 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_Helicase PF02689.14 KNZ77833.1 - 4e-05 21.8 0.0 4.2e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KNZ77834.1 - 1.3e-34 119.9 0.0 1.6e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ77834.1 - 0.024 14.6 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ77834.1 - 0.064 13.0 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ77834.1 - 0.16 12.3 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Helitron_like_N PF14214.6 KNZ77835.1 - 3.4e-26 92.6 0.0 4.2e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ77835.1 - 0.09 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Inovirus Gp2 Pertussis_S2S3 PF02918.15 KNZ77836.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain Ribosomal_L24e PF01246.20 KNZ77837.1 - 6.5e-30 103.2 0.2 6.5e-30 103.2 0.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L24e Ets PF00178.22 KNZ77837.1 - 1.1 9.8 4.0 0.28 11.7 0.4 1.7 2 0 0 2 2 2 0 Ets-domain Mo25 PF08569.11 KNZ77838.1 - 4e-124 414.2 13.6 4.4e-124 414.1 13.6 1.0 1 0 0 1 1 1 1 Mo25-like vATP-synt_AC39 PF01992.16 KNZ77838.1 - 0.051 13.1 5.6 0.061 12.8 4.5 1.7 2 1 0 2 2 2 0 ATP synthase (C/AC39) subunit EthD PF07110.11 KNZ77839.1 - 0.11 13.7 0.0 0.19 12.9 0.0 1.6 1 0 0 1 1 1 0 EthD domain Pkinase PF00069.25 KNZ77840.1 - 1.3e-10 41.1 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ77840.1 - 1.5e-06 28.4 1.1 3.7e-05 23.8 0.3 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ77840.1 - 1.1e-05 25.1 0.1 1.8e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 KNZ77840.1 - 3.7e-05 23.1 0.0 4.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 KNZ77840.1 - 5.5e-05 22.8 0.0 0.00056 19.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 KNZ77840.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Saccharop_dh_N PF04455.12 KNZ77840.1 - 0.0035 17.7 1.2 0.024 15.0 0.0 2.6 3 0 0 3 3 3 1 LOR/SDH bifunctional enzyme conserved region PIP49_C PF12260.8 KNZ77840.1 - 0.024 14.3 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RSN1_7TM PF02714.15 KNZ77841.1 - 8.8e-66 222.0 24.3 5.7e-64 216.1 24.3 2.5 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KNZ77841.1 - 7.8e-35 120.7 0.0 1.1e-34 120.2 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KNZ77841.1 - 2.3e-33 115.2 2.4 2.3e-33 115.2 2.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport EF-hand_7 PF13499.6 KNZ77843.1 - 1.9e-11 44.2 0.0 3e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KNZ77843.1 - 3.1e-11 42.2 0.2 0.00018 21.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KNZ77843.1 - 1.3e-09 36.9 0.0 0.00044 19.6 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KNZ77843.1 - 5e-06 26.7 0.0 0.012 15.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 KNZ77843.1 - 0.00055 19.7 0.0 0.0047 16.7 0.1 2.3 2 1 1 3 3 3 1 EF-hand domain pair SapB_1 PF05184.15 KNZ77843.1 - 0.028 14.4 0.1 6.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_11 PF08976.11 KNZ77843.1 - 0.19 12.6 0.0 0.34 11.8 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain DDE_Tnp_IS66_C PF13817.6 KNZ77843.1 - 0.21 11.8 0.3 0.55 10.5 0.1 1.7 2 0 0 2 2 2 0 IS66 C-terminal element EF-hand_5 PF13202.6 KNZ77843.1 - 0.3 10.7 1.0 0.85 9.2 0.1 2.2 2 1 1 3 3 3 0 EF hand MFS_1 PF07690.16 KNZ77844.1 - 1.9e-46 158.6 47.7 6.5e-33 114.1 9.8 3.6 2 1 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 KNZ77844.1 - 0.0021 16.6 6.7 0.0021 16.6 6.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PCRF PF03462.18 KNZ77845.1 - 2.4e-52 177.6 0.7 5.4e-52 176.5 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 KNZ77845.1 - 1.3e-34 118.6 3.5 2.6e-34 117.6 3.5 1.5 1 0 0 1 1 1 1 RF-1 domain PIF1 PF05970.14 KNZ77847.1 - 3e-52 178.0 0.0 3.7e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ77847.1 - 5.8e-06 26.2 0.0 7.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ77847.1 - 0.0027 17.7 0.0 0.017 15.1 0.0 1.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ77847.1 - 0.0052 17.2 0.0 0.0068 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 KNZ77847.1 - 0.019 15.3 0.1 0.074 13.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 KNZ77847.1 - 0.02 14.6 0.1 0.05 13.3 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KNZ77847.1 - 0.074 12.6 0.1 0.097 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ77847.1 - 0.12 12.8 0.1 0.7 10.3 0.1 2.3 1 1 0 1 1 1 0 RNA helicase DUF2791 PF10923.8 KNZ77847.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) PIF1 PF05970.14 KNZ77848.1 - 1.7e-16 60.4 0.0 2.1e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ77848.1 - 0.035 13.8 1.2 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal p450 PF00067.22 KNZ77849.1 - 7.1e-46 156.9 0.1 9.2e-46 156.5 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 KNZ77850.1 - 5.7e-179 595.5 0.4 6.4e-179 595.3 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KNZ77850.1 - 0.018 14.5 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) SPX PF03105.19 KNZ77851.1 - 3.9e-39 135.7 0.8 5.6e-39 135.2 0.8 1.2 1 0 0 1 1 1 1 SPX domain Suv3_N PF18114.1 KNZ77851.1 - 0.21 11.7 1.4 1.2 9.3 0.1 2.8 4 0 0 4 4 4 0 Suv3 helical N-terminal domain CMAS PF02353.20 KNZ77852.1 - 7.1e-28 97.7 0.0 6.6e-26 91.2 0.0 2.0 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KNZ77852.1 - 9.6e-08 32.6 0.0 2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ77852.1 - 1.3e-07 32.2 0.0 2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ77852.1 - 0.0045 16.8 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ77852.1 - 0.0051 17.5 0.0 0.0079 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CBM_14 PF01607.24 KNZ77854.1 - 0.07 13.3 0.2 0.07 13.3 0.2 4.9 2 1 3 5 5 5 0 Chitin binding Peritrophin-A domain cEGF PF12662.7 KNZ77854.1 - 8.9 6.4 24.4 0.36 10.8 1.1 5.5 3 2 2 5 5 5 0 Complement Clr-like EGF-like Myosin_head PF00063.21 KNZ77855.1 - 4.9e-240 798.4 0.0 9.3e-239 794.1 0.0 2.6 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 KNZ77855.1 - 1.6e-22 79.3 282.2 2.1e-17 62.3 163.4 5.7 2 2 1 4 4 4 3 Myosin tail Myosin_N PF02736.19 KNZ77855.1 - 1.7e-10 40.6 0.5 4.5e-10 39.2 0.5 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain APG6_N PF17675.1 KNZ77855.1 - 0.0023 18.5 17.4 0.0023 18.5 17.4 15.4 3 3 13 17 17 17 2 Apg6 coiled-coil region AAA_22 PF13401.6 KNZ77855.1 - 0.038 14.3 0.1 0.038 14.3 0.1 5.3 4 1 0 4 4 4 0 AAA domain TsaE PF02367.17 KNZ77855.1 - 0.09 12.8 0.2 0.73 9.8 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KNZ77855.1 - 0.11 12.8 4.7 1.6 9.1 0.1 3.9 2 1 0 2 2 2 0 AAA domain ATP19 PF11022.8 KNZ77856.1 - 5e-10 39.6 1.2 5.9e-10 39.4 1.2 1.1 1 0 0 1 1 1 1 ATP synthase subunit K An_peroxidase PF03098.15 KNZ77857.1 - 2.9e-31 108.6 0.0 5e-21 74.9 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase Integrase_H2C2 PF17921.1 KNZ77859.1 - 0.013 15.6 0.3 0.051 13.7 0.0 2.2 2 0 0 2 2 2 0 Integrase zinc binding domain PriCT_2 PF08707.11 KNZ77859.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.4 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Aconitase_C PF00694.19 KNZ77862.1 - 5.8e-18 65.5 0.0 6.2e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase C-terminal domain IPK PF03770.16 KNZ77863.1 - 7.9e-31 107.5 0.0 1.1e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase FMO-like PF00743.19 KNZ77865.1 - 5.9e-15 54.7 0.0 8.9e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ77865.1 - 4.5e-13 49.1 0.0 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ77865.1 - 5.3e-11 42.3 0.0 8e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ77865.1 - 1.9e-08 34.4 1.4 1e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KNZ77865.1 - 2.2e-08 33.6 0.0 8.2e-06 25.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KNZ77865.1 - 4.8e-06 26.4 0.0 0.25 10.9 0.0 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox PF00070.27 KNZ77865.1 - 0.00042 20.8 0.3 1.4 9.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 KNZ77865.1 - 0.00077 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KNZ77865.1 - 0.0037 17.3 4.7 0.15 12.0 0.1 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KNZ77865.1 - 0.03 13.4 1.9 0.098 11.7 0.2 2.3 2 1 1 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KNZ77865.1 - 0.057 12.5 0.0 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KNZ77865.1 - 0.071 11.8 0.8 0.18 10.5 0.1 2.0 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.6 KNZ77865.1 - 0.15 12.5 0.1 21 5.6 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 KNZ77865.1 - 0.19 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KNZ77865.1 - 0.43 9.8 0.0 0.43 9.8 0.0 2.0 3 0 0 3 3 3 0 Thi4 family FMO-like PF00743.19 KNZ77867.1 - 5.9e-14 51.4 0.0 9.9e-14 50.6 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KNZ77867.1 - 1.7e-13 50.5 0.0 6.4e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ77867.1 - 1.1e-11 44.6 0.0 1.7e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ77867.1 - 4.9e-09 36.3 0.1 1.1e-07 32.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KNZ77867.1 - 1.6e-08 34.1 0.0 6.2e-06 25.6 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KNZ77867.1 - 3.9e-06 26.7 0.0 0.18 11.3 0.0 3.4 3 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KNZ77867.1 - 0.00011 22.7 0.2 0.84 10.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ77867.1 - 0.00035 20.6 2.1 0.091 12.7 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KNZ77867.1 - 0.0025 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KNZ77867.1 - 0.0038 17.6 0.0 1.9 9.0 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KNZ77867.1 - 0.012 14.7 0.4 0.21 10.6 0.1 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 KNZ77867.1 - 0.019 14.1 0.0 1.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KNZ77867.1 - 0.057 12.1 0.5 0.16 10.6 0.0 2.0 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 KNZ77867.1 - 0.096 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 KNZ77867.1 - 0.16 12.0 0.1 2.3 8.2 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 KNZ77867.1 - 0.27 10.5 0.0 0.27 10.5 0.0 2.0 3 0 0 3 3 3 0 Thi4 family Herpes_gE PF02480.16 KNZ77868.1 - 0.062 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KNZ77868.1 - 0.097 13.6 0.0 0.21 12.5 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KNZ77868.1 - 0.11 12.5 1.6 0.34 10.8 0.0 2.3 2 1 0 2 2 2 0 TMEM154 protein family Hamartin PF04388.12 KNZ77868.1 - 0.15 10.7 4.6 0.16 10.6 4.6 1.2 1 0 0 1 1 1 0 Hamartin protein stn_TNFRSF12A PF12191.8 KNZ77868.1 - 0.2 11.9 1.8 0.51 10.6 1.8 1.7 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain HTH_39 PF14090.6 KNZ77869.1 - 0.11 12.3 0.2 0.24 11.2 0.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain gag-asp_proteas PF13975.6 KNZ77871.1 - 1.1e-05 25.9 0.0 1.3e-05 25.7 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ77871.1 - 0.0058 17.3 0.0 0.0072 16.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ77871.1 - 0.0072 16.1 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease MgtE PF01769.16 KNZ77875.1 - 3.3e-34 117.9 14.5 8.8e-17 61.6 2.5 2.7 2 1 0 2 2 2 2 Divalent cation transporter Cwf_Cwc_15 PF04889.12 KNZ77875.1 - 7.7 6.2 5.3 12 5.5 5.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ada3 PF10198.9 KNZ77876.1 - 4.1e-27 94.9 0.8 4.1e-27 94.9 0.8 2.6 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Herpes_UL25 PF01499.16 KNZ77876.1 - 0.38 9.2 2.1 0.57 8.6 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family RNA_polI_A34 PF08208.11 KNZ77877.1 - 2.7e-26 92.9 9.4 2.7e-26 92.9 9.4 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 zf-RING_2 PF13639.6 KNZ77878.1 - 3.3e-06 27.3 5.4 3.3e-06 27.3 5.4 2.1 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 KNZ77878.1 - 0.00019 21.2 5.8 0.00035 20.4 5.8 1.5 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.17 KNZ77878.1 - 0.00062 19.4 0.5 0.0012 18.5 0.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.8 KNZ77878.1 - 0.0045 17.1 4.3 0.0045 17.1 4.3 2.1 3 0 0 3 3 3 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 KNZ77878.1 - 0.0058 16.5 1.5 0.018 15.0 1.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 KNZ77878.1 - 0.015 14.8 1.4 0.029 13.9 1.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 KNZ77878.1 - 0.037 14.1 3.7 0.12 12.4 3.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-PHD-like PF15446.6 KNZ77878.1 - 0.063 12.9 3.1 0.13 11.9 3.1 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain EGF_alliinase PF04863.13 KNZ77878.1 - 0.096 13.1 0.8 0.58 10.6 0.1 2.3 2 0 0 2 2 2 0 Alliinase EGF-like domain C1_1 PF00130.22 KNZ77878.1 - 1 9.3 9.1 0.042 13.7 3.0 1.9 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OTT_1508_deam PF14441.6 KNZ77879.1 - 3.9e-08 33.2 0.0 8.7e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase FPP PF05911.11 KNZ77880.1 - 0.007 14.6 12.8 0.008 14.4 12.8 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil TMF_TATA_bd PF12325.8 KNZ77880.1 - 0.018 15.2 2.8 0.018 15.2 2.8 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 KNZ77880.1 - 0.058 13.4 19.4 0.15 12.0 17.4 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 KNZ77880.1 - 0.058 12.7 19.9 0.96 8.8 10.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 KNZ77880.1 - 0.14 10.7 5.0 0.16 10.5 5.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2808 PF10989.8 KNZ77880.1 - 0.15 12.0 0.2 0.23 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) zf-CCCH_6 PF18585.1 KNZ77880.1 - 0.25 11.2 2.0 1.8 8.5 0.3 2.4 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 PV-1 PF06637.11 KNZ77880.1 - 1.1 8.0 11.8 1.3 7.7 11.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) SKA2 PF16740.5 KNZ77880.1 - 1.5 8.6 12.9 0.93 9.3 3.0 2.8 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 YabA PF06156.13 KNZ77880.1 - 2.4 8.8 14.5 1.6 9.4 6.4 2.9 1 1 2 3 3 3 0 Initiation control protein YabA V_ATPase_I PF01496.19 KNZ77880.1 - 3.3 5.5 7.7 4 5.2 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 KNZ77880.1 - 5.8 7.4 8.3 5.1 7.6 0.5 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KNZ77880.1 - 7.2 5.9 10.8 9.7 5.4 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 KNZ77880.1 - 7.9 5.7 7.4 1.8 7.8 2.3 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 KNZ77880.1 - 9.1 5.0 8.6 11 4.8 8.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 KNZ77880.1 - 10 5.4 13.6 54 3.0 13.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_1 PF00515.28 KNZ77881.1 - 1.6e-15 56.1 11.6 7e-08 32.0 1.3 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ77881.1 - 1.2e-13 50.0 12.4 5.2e-06 26.2 1.4 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ77881.1 - 3.4e-07 30.8 24.4 1.5e-05 25.6 9.9 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ77881.1 - 4.9e-07 29.4 9.8 0.0024 17.9 0.9 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ77881.1 - 5.3e-07 29.8 13.9 0.00018 21.7 1.9 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ77881.1 - 1.1e-06 29.0 13.8 5e-06 26.9 8.9 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ77881.1 - 1.1e-05 25.5 8.3 1.3e-05 25.2 3.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-CCCH_4 PF18044.1 KNZ77881.1 - 1.4e-05 24.8 13.2 0.015 15.1 6.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger TPR_17 PF13431.6 KNZ77881.1 - 3.9e-05 23.7 3.1 0.24 11.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ77881.1 - 4.7e-05 23.0 12.4 0.0063 16.2 7.4 3.2 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.6 KNZ77881.1 - 0.00016 22.2 12.3 0.078 13.8 3.8 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ77881.1 - 0.0015 19.0 11.4 0.19 12.4 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KNZ77881.1 - 0.0031 17.0 3.5 0.0055 16.1 3.5 1.4 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_10 PF13374.6 KNZ77881.1 - 0.0071 16.2 11.7 0.02 14.7 2.1 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat zf-CCCH_2 PF14608.6 KNZ77881.1 - 0.0085 16.5 10.9 0.057 13.9 5.4 2.6 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger DUF3856 PF12968.7 KNZ77881.1 - 0.0096 16.0 4.0 0.029 14.4 3.9 1.7 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_7 PF13176.6 KNZ77881.1 - 0.013 15.5 9.0 0.059 13.4 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_42M PF08532.10 KNZ77881.1 - 0.027 13.9 5.3 30 4.0 0.0 4.9 5 1 0 5 5 5 0 Beta-galactosidase trimerisation domain FIST PF08495.10 KNZ77881.1 - 0.1 12.6 0.3 46 4.0 0.0 3.4 3 1 0 3 3 3 0 FIST N domain Fis1_TPR_C PF14853.6 KNZ77881.1 - 0.13 12.3 0.2 0.45 10.6 0.2 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KNZ77881.1 - 0.25 11.6 6.1 0.52 10.6 3.8 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 zf_CCCH_4 PF18345.1 KNZ77881.1 - 0.63 10.2 17.1 0.071 13.2 9.5 2.7 2 1 0 2 2 2 0 Zinc finger domain MscS_porin PF12795.7 KNZ77881.1 - 1.5 8.3 10.4 2.8 7.4 10.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain zf-CCCH PF00642.24 KNZ77881.1 - 7.7 6.6 12.0 1.3 9.0 4.9 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mak10 PF04112.13 KNZ77882.1 - 6.2e-49 165.7 0.0 1.1e-48 164.9 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.25 KNZ77883.1 - 1.3e-72 244.6 0.0 1.6e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 KNZ77883.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) p450 PF00067.22 KNZ77886.1 - 1.1e-07 31.0 0.0 0.00014 20.8 0.0 2.5 3 0 0 3 3 3 2 Cytochrome P450 MRP-S33 PF08293.11 KNZ77887.1 - 7.4e-23 80.6 1.2 9.6e-23 80.2 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Helicase_C PF00271.31 KNZ77888.1 - 1.2e-10 41.7 0.0 5.1e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 KNZ77888.1 - 4.4e-06 26.5 0.3 1.1e-05 25.3 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 KNZ77888.1 - 0.062 13.2 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 TFB6 PF17110.5 KNZ77890.1 - 6.1e-06 26.1 0.3 1.2e-05 25.1 0.3 1.6 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH MFS_1 PF07690.16 KNZ77892.1 - 2.3e-32 112.3 39.0 1.7e-31 109.5 37.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ77892.1 - 7.3e-09 35.0 11.5 7.3e-09 35.0 11.5 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 KNZ77892.1 - 1.4 7.7 12.1 0.092 11.6 6.1 1.9 2 0 0 2 2 2 0 MFS_1 like family Lipase_3 PF01764.25 KNZ77893.1 - 5.7e-08 32.7 0.1 1.9e-06 27.8 0.1 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KNZ77893.1 - 0.0053 17.4 0.1 0.011 16.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Carn_acyltransf PF00755.20 KNZ77895.1 - 2.6e-186 620.7 0.0 8.9e-93 311.9 0.0 2.0 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase F-box-like PF12937.7 KNZ77896.1 - 0.0047 16.8 0.7 0.014 15.3 0.1 2.2 3 0 0 3 3 3 1 F-box-like DUF2857 PF11198.8 KNZ77896.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2857) BTB PF00651.31 KNZ77899.1 - 0.026 14.8 0.0 0.066 13.4 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain ATG101 PF07855.12 KNZ77901.1 - 4.3e-24 85.3 0.7 2.2e-22 79.7 0.7 2.2 1 1 0 1 1 1 1 Autophagy-related protein 101 OPA3 PF07047.12 KNZ77902.1 - 2.9e-40 136.9 0.1 4.4e-40 136.3 0.1 1.3 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Noelin-1 PF12308.8 KNZ77902.1 - 0.18 11.8 3.3 0.15 12.1 1.5 1.7 2 0 0 2 2 2 0 Neurogenesis glycoprotein SHE3 PF17078.5 KNZ77902.1 - 0.32 10.7 3.5 0.56 9.9 3.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 KNZ77902.1 - 0.86 9.9 4.4 2.4 8.5 0.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cellulase PF00150.18 KNZ77903.1 - 3.8e-13 49.5 0.0 6.8e-07 29.0 0.0 2.8 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 KNZ77903.1 - 2.9e-10 40.5 0.0 3.6e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 KNZ77903.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_7 PF00840.20 KNZ77904.1 - 7.9e-211 700.4 15.3 7.9e-211 700.4 15.3 1.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KNZ77904.1 - 7.2e-12 45.0 14.6 7.2e-12 45.0 14.6 4.6 4 1 0 4 4 4 1 Fungal cellulose binding domain Aldolase_II PF00596.21 KNZ77905.1 - 8.3e-37 126.9 0.1 3.5e-36 124.9 0.0 1.8 1 1 1 2 2 2 1 Class II Aldolase and Adducin N-terminal domain rve PF00665.26 KNZ77906.1 - 0.0043 17.2 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1643 PF07799.12 KNZ77906.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) eIF2A PF08662.11 KNZ77907.1 - 9.1e-77 257.3 0.0 4.9e-76 254.9 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 KNZ77907.1 - 0.022 15.6 0.1 4.2 8.4 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Proteasome_A_N PF10584.9 KNZ77907.1 - 0.11 12.2 0.6 87 2.9 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 KNZ77907.1 - 0.4 10.7 1.7 14 5.7 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat adh_short_C2 PF13561.6 KNZ77909.1 - 5.7e-41 140.6 0.0 8.8e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ77909.1 - 1.2e-39 135.8 0.0 2.2e-39 135.0 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.19 KNZ77909.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.10 KNZ77909.1 - 0.014 15.4 1.2 0.027 14.4 0.1 2.1 2 1 0 2 2 2 0 KR domain Shikimate_DH PF01488.20 KNZ77909.1 - 0.022 14.8 0.1 0.036 14.1 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KNZ77909.1 - 0.03 13.8 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KNZ77909.1 - 0.04 13.8 0.2 0.057 13.3 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DEDD_Tnp_IS110 PF01548.17 KNZ77909.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Transposase NAD_binding_7 PF13241.6 KNZ77909.1 - 0.12 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Cadherin_5 PF17892.1 KNZ77909.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Cadherin-like domain Pyr_redox PF00070.27 KNZ77909.1 - 0.16 12.5 0.8 0.26 11.9 0.2 1.5 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase RhoGEF PF00621.20 KNZ77910.1 - 3.5e-37 128.4 1.6 7e-37 127.4 1.6 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.28 KNZ77910.1 - 2.9e-20 71.6 0.5 7.3e-13 47.9 0.1 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 KNZ77910.1 - 2.4e-19 68.9 1.8 4e-10 39.4 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.7 KNZ77910.1 - 2.6e-16 59.4 0.0 5.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand PH_13 PF16652.5 KNZ77910.1 - 4.6e-15 55.8 0.1 2.1e-14 53.6 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 KNZ77910.1 - 1.2e-10 40.9 0.0 6.8e-06 25.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.20 KNZ77910.1 - 0.011 15.5 0.1 0.025 14.4 0.1 1.6 1 0 0 1 1 1 0 WH2 motif SH3_10 PF17902.1 KNZ77910.1 - 0.028 14.5 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 SH3 domain EF-hand_1 PF00036.32 KNZ77910.1 - 0.06 12.9 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 EF hand PH_16 PF17838.1 KNZ77910.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 PH domain PH PF00169.29 KNZ77910.1 - 0.11 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 PH domain F-box-like PF12937.7 KNZ77911.1 - 2.4e-10 40.1 1.3 6.5e-10 38.7 1.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KNZ77911.1 - 0.096 13.1 0.4 0.6 10.6 0.4 2.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KNZ77912.1 - 1.6e-06 27.9 3.2 5.4e-06 26.2 3.2 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KNZ77912.1 - 3.6 8.2 10.0 13 6.4 0.5 4.9 4 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 KNZ77914.1 - 8.7e-48 163.0 0.0 1.5e-47 162.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77914.1 - 4.3e-22 78.6 0.0 8.5e-22 77.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ77914.1 - 0.0019 17.1 0.1 0.004 16.0 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 KNZ77914.1 - 0.028 13.4 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Transcrip_reg PF01709.20 KNZ77914.1 - 0.05 13.0 1.3 0.097 12.1 1.3 1.4 1 0 0 1 1 1 0 Transcriptional regulator RIO1 PF01163.22 KNZ77914.1 - 0.099 12.2 0.0 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 RIO1 family Cyclase PF04199.13 KNZ77915.1 - 2.5e-14 53.7 0.0 3.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Shugoshin_C PF07557.11 KNZ77916.1 - 5.2e-11 42.1 3.8 2.8e-10 39.8 3.8 2.4 1 0 0 1 1 1 1 Shugoshin C terminus Shugoshin_N PF07558.11 KNZ77916.1 - 2.9e-08 33.4 2.7 6.4e-08 32.3 2.7 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region KASH_CCD PF14662.6 KNZ77916.1 - 0.0076 16.1 4.6 0.014 15.2 4.6 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Paramyxo_C PF01692.18 KNZ77916.1 - 0.05 13.0 0.3 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C DUF3584 PF12128.8 KNZ77916.1 - 0.12 9.9 2.5 0.18 9.3 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YabA PF06156.13 KNZ77916.1 - 3.8 8.2 5.4 1.3 9.7 2.5 1.7 2 0 0 2 2 2 0 Initiation control protein YabA PP2C PF00481.21 KNZ77918.1 - 4e-16 59.4 0.0 6.2e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KNZ77918.1 - 0.0029 17.6 0.0 0.039 13.9 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) MFS_1 PF07690.16 KNZ77919.1 - 3.2e-33 115.1 48.1 3.2e-33 115.1 48.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TraI_2_C PF07515.11 KNZ77919.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term adh_short PF00106.25 KNZ77920.1 - 1.8e-27 96.1 0.0 3.4e-26 91.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ77920.1 - 1.1e-16 61.1 0.0 2.5e-15 56.7 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ77920.1 - 0.00022 21.2 0.1 0.00044 20.2 0.1 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KNZ77920.1 - 0.003 17.5 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 KNZ77920.1 - 0.041 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus 2-Hacid_dh_C PF02826.19 KNZ77920.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Terpene_synth_C PF03936.16 KNZ77923.1 - 0.0015 18.0 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Pinin_SDK_N PF04697.13 KNZ77924.1 - 1.6 9.4 9.8 4.5 7.9 9.2 1.9 1 1 0 1 1 1 0 pinin/SDK conserved region LRR_6 PF13516.6 KNZ77924.1 - 3.3 8.0 6.1 2.5e+02 2.1 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich repeat CDC45 PF02724.14 KNZ77924.1 - 8.6 4.5 12.4 12 4.0 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PcfK PF14058.6 KNZ77924.1 - 9.7 6.5 11.4 26 5.1 11.4 1.7 1 0 0 1 1 1 0 PcfK-like protein MFS_1 PF07690.16 KNZ77925.1 - 8.1e-31 107.2 35.3 8.1e-31 107.2 35.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Urocanase PF01175.18 KNZ77925.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Urocanase Rossmann-like domain DUF1516 PF07457.11 KNZ77925.1 - 0.23 11.7 5.2 0.41 10.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1516) CPP1-like PF11833.8 KNZ77925.1 - 1 9.0 16.5 0.14 11.8 6.5 2.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Piwi PF02171.17 KNZ77926.1 - 3.4e-79 266.2 0.0 4.6e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KNZ77926.1 - 1.7e-20 74.1 0.1 3.2e-20 73.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KNZ77926.1 - 3e-16 58.8 0.1 6.3e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KNZ77926.1 - 2.4e-15 56.5 3.2 2.6e-15 56.4 0.1 2.5 3 0 0 3 3 3 1 Mid domain of argonaute ArgoL2 PF16488.5 KNZ77926.1 - 1.9e-09 37.7 0.0 4.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KNZ77926.1 - 1.1e-08 35.0 0.0 2.4e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DPM3 PF08285.11 KNZ77927.1 - 5.8 7.2 6.8 30 4.9 0.4 3.3 3 1 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) C2 PF00168.30 KNZ77928.1 - 1.3e-15 57.5 0.0 2.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Peptidase_C48 PF02902.19 KNZ77929.1 - 0.00014 21.7 2.6 0.00021 21.2 2.6 1.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain C2 PF00168.30 KNZ77930.1 - 5.7e-15 55.5 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Glyco_hydro_31 PF01055.26 KNZ77932.1 - 6.3e-150 500.2 1.5 7.6e-150 499.9 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KNZ77932.1 - 3.7e-34 117.4 0.0 7.5e-34 116.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KNZ77932.1 - 1.6e-12 47.6 0.6 1.6e-12 47.6 0.6 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF3255 PF11631.8 KNZ77932.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) F-box-like PF12937.7 KNZ77933.1 - 1.1e-07 31.7 0.3 2.8e-07 30.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.21 KNZ77934.1 - 1.4e-71 241.1 0.0 1.8e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RT_RNaseH_2 PF17919.1 KNZ77935.1 - 9.8e-18 64.1 0.2 1.3e-17 63.7 0.2 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ77935.1 - 1.9e-13 50.6 0.1 3.9e-13 49.6 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Auxin_BP PF02041.16 KNZ77935.1 - 0.034 13.8 0.0 0.047 13.4 0.0 1.3 1 1 0 1 1 1 0 Auxin binding protein Ion_trans PF00520.31 KNZ77936.1 - 6.7e-19 68.1 22.4 8.4e-19 67.8 22.4 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 KNZ77936.1 - 1.7e-10 40.7 8.4 1.7e-10 40.7 8.4 3.1 2 2 1 3 3 3 1 Ion channel Lig_chan PF00060.26 KNZ77936.1 - 0.0028 17.5 0.7 0.0028 17.5 0.7 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel BBE PF08031.12 KNZ77937.1 - 5.3e-09 36.0 0.8 1.4e-08 34.7 0.8 1.8 1 1 0 1 1 1 1 Berberine and berberine like DUF726 PF05277.12 KNZ77937.1 - 0.2 10.5 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Filament PF00038.21 KNZ77938.1 - 0.0022 17.6 4.0 0.003 17.2 4.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein GIT_CC PF16559.5 KNZ77938.1 - 0.045 13.6 1.3 8.3 6.4 0.2 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 KNZ77938.1 - 0.073 12.9 9.3 1.1 9.1 3.3 2.3 1 1 1 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 KNZ77938.1 - 0.12 12.4 8.6 0.26 11.3 8.6 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KNZ77938.1 - 0.15 10.9 6.9 0.19 10.6 6.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-H PF05837.12 KNZ77938.1 - 0.27 11.7 6.8 0.4 11.1 6.1 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF3958 PF13125.6 KNZ77938.1 - 0.54 10.5 5.7 3.8 7.7 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) YabA PF06156.13 KNZ77938.1 - 0.58 10.8 5.0 3.3 8.4 5.0 2.0 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 KNZ77938.1 - 1.4 9.4 8.7 79 3.8 8.7 2.4 1 1 0 1 1 1 0 Cell division protein ZapB Spc24 PF08286.11 KNZ77938.1 - 5.5 7.3 8.1 58 4.0 8.1 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 BCS1_N PF08740.11 KNZ77939.1 - 3.4e-31 108.7 0.5 3.4e-31 108.7 0.5 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 KNZ77939.1 - 7.5e-21 74.9 0.0 9.7e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KNZ77939.1 - 0.0012 18.7 0.0 0.0068 16.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ77939.1 - 0.0093 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KNZ77939.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KNZ77939.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 KNZ77939.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KNZ77939.1 - 0.042 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_6 PF12774.7 KNZ77939.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_24 PF13479.6 KNZ77939.1 - 0.097 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ77939.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KNZ77939.1 - 0.11 13.0 0.1 0.64 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KNZ77939.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KNZ77939.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 KNZ77939.1 - 0.37 11.0 3.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.23 KNZ77942.1 - 4e-32 110.9 2.9 9e-32 109.7 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KNZ77942.1 - 5.6e-09 36.0 0.3 1.4e-08 34.7 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Tropomyosin PF00261.20 KNZ77943.1 - 0.015 14.7 3.6 0.022 14.1 3.6 1.2 1 0 0 1 1 1 0 Tropomyosin phiKZ_IP PF12699.7 KNZ77943.1 - 0.016 14.4 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Med9 PF07544.13 KNZ77943.1 - 0.15 12.2 0.4 0.32 11.1 0.2 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Abhydrolase_6 PF12697.7 KNZ77944.1 - 4.9e-07 30.6 0.0 1.3e-06 29.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ77944.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Myb_DNA-binding PF00249.31 KNZ77945.1 - 3.7e-18 65.4 0.1 1.5e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ77945.1 - 2.8e-13 49.9 0.0 1.6e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KNZ77945.1 - 7.5e-06 25.9 0.1 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 SLIDE Prefoldin PF02996.17 KNZ77946.1 - 5.9e-28 97.2 3.4 2.3e-25 88.8 3.4 2.3 1 1 0 1 1 1 1 Prefoldin subunit BCAS3 PF12490.8 KNZ77946.1 - 0.0033 17.0 2.0 0.015 14.8 0.6 2.0 1 1 0 2 2 2 1 Breast carcinoma amplified sequence 3 Ran-binding PF05508.11 KNZ77946.1 - 0.016 14.2 0.9 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 RanGTP-binding protein NPV_P10 PF05531.12 KNZ77946.1 - 0.14 12.6 4.5 5.6 7.5 0.1 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 KNZ77946.1 - 0.19 11.0 1.8 0.55 9.5 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 KNZ77946.1 - 0.26 11.1 4.9 7.4 6.4 0.0 3.2 3 0 0 3 3 3 0 Septum formation initiator Lebercilin PF15619.6 KNZ77946.1 - 1.1 8.9 9.8 2.4 7.8 1.8 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease XhlA PF10779.9 KNZ77946.1 - 3.6 7.9 5.6 36 4.6 0.1 3.2 3 0 0 3 3 3 0 Haemolysin XhlA RRM_1 PF00076.22 KNZ77947.1 - 1.1e-71 236.6 0.1 5.1e-20 71.1 0.0 5.7 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ77947.1 - 3.3e-07 30.1 0.0 0.012 15.5 0.0 4.5 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_2 PF04059.12 KNZ77947.1 - 0.0045 17.2 0.0 16 5.8 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif 2 RRM_3 PF08777.11 KNZ77947.1 - 0.007 16.4 0.2 2.3 8.3 0.0 4.2 5 0 0 5 5 5 1 RNA binding motif DUF3343 PF11823.8 KNZ77947.1 - 0.17 11.4 0.1 0.82 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Ku_C PF03730.14 KNZ77947.1 - 0.74 10.5 7.9 0.081 13.6 2.3 2.3 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm SNF2_N PF00176.23 KNZ77948.1 - 1.3e-47 162.3 0.0 2.3e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.25 KNZ77948.1 - 6.1e-06 26.0 11.4 1e-05 25.3 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ77948.1 - 6.9e-06 25.8 12.8 1.2e-05 25.1 12.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ77948.1 - 6e-05 22.8 8.2 0.0001 22.1 8.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 KNZ77948.1 - 0.00028 21.1 14.9 0.0005 20.3 14.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ77948.1 - 0.0031 17.3 14.8 0.0059 16.4 14.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 KNZ77948.1 - 0.004 17.5 0.1 0.017 15.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KNZ77948.1 - 0.0041 17.0 13.5 0.0077 16.2 13.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KNZ77948.1 - 0.01 16.1 9.6 0.026 14.8 9.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KNZ77948.1 - 0.059 13.4 4.9 0.14 12.2 4.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KNZ77948.1 - 0.16 12.0 6.8 0.47 10.5 6.9 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 KNZ77948.1 - 4.5 7.0 10.7 8.8 6.0 10.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 KNZ77948.1 - 7.4 6.8 10.8 14 5.9 10.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LPD29 PF18847.1 KNZ77950.1 - 0.039 14.9 0.3 0.36 11.8 0.0 2.6 3 1 0 3 3 3 0 Large polyvalent protein associated domain 29 BatD PF13584.6 KNZ77952.1 - 0.019 13.8 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance MGC-24 PF05283.11 KNZ77952.1 - 0.02 15.3 0.8 0.041 14.3 0.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 KNZ77952.1 - 0.052 14.4 0.0 0.09 13.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 KNZ77952.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.6 KNZ77952.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless PMP1_2 PF08114.11 KNZ77952.1 - 0.14 11.9 0.2 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Peptidase_M56 PF05569.11 KNZ77952.1 - 0.2 10.8 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 LapA_dom PF06305.11 KNZ77952.1 - 0.44 10.4 1.5 0.61 9.9 0.4 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain STE3 PF02076.15 KNZ77953.1 - 2e-53 181.5 17.7 2.7e-53 181.1 17.7 1.1 1 0 0 1 1 1 1 Pheromone A receptor BPD_transp_2 PF02653.16 KNZ77953.1 - 7.7 5.6 13.0 1.7 7.8 2.5 2.3 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component STE3 PF02076.15 KNZ77954.1 - 9.9e-104 346.6 10.8 1.2e-103 346.3 10.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor CBF PF03914.17 KNZ77955.1 - 3.1e-29 102.2 3.9 3.1e-29 102.2 3.9 2.3 2 1 0 2 2 2 1 CBF/Mak21 family STE3 PF02076.15 KNZ77956.1 - 8e-94 314.1 13.1 9.3e-94 313.9 13.1 1.0 1 0 0 1 1 1 1 Pheromone A receptor PEMT PF04191.13 KNZ77957.1 - 2e-13 50.6 0.5 1.2e-12 48.2 0.1 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KNZ77957.1 - 3.3e-12 46.6 0.1 5e-11 42.9 0.1 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KNZ77957.1 - 1.7e-07 30.4 0.5 2.3e-07 29.9 0.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KNZ77957.1 - 0.0047 16.5 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3955 PF13127.6 KNZ77957.1 - 0.14 12.0 0.6 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3955) PEMT PF04191.13 KNZ77958.1 - 1.9e-05 25.0 1.9 0.00032 21.1 0.4 2.0 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 KNZ77958.1 - 0.0046 15.8 0.1 0.0054 15.5 0.1 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 KNZ77958.1 - 0.012 16.0 1.0 0.068 13.6 0.3 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KNZ77959.1 - 2.8e-13 50.2 0.5 2.6e-11 43.8 0.8 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KNZ77959.1 - 3.3e-12 46.6 0.2 1.7e-10 41.2 0.1 2.1 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 KNZ77959.1 - 1.1e-07 31.0 0.1 1.4e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KNZ77959.1 - 0.029 13.9 0.1 0.039 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) CNOT11 PF10155.9 KNZ77960.1 - 7.9e-19 68.0 0.0 1.4e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Pkinase PF00069.25 KNZ77961.1 - 9.4e-74 248.1 0.3 9.4e-74 248.1 0.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77961.1 - 2.2e-52 177.9 0.3 2.2e-52 177.9 0.3 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 KNZ77961.1 - 1.7e-23 82.7 0.0 5.2e-23 81.2 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 KNZ77961.1 - 5.4e-07 29.2 0.0 9.9e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KNZ77961.1 - 7.1e-07 28.5 1.3 1.1e-06 27.8 1.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 KNZ77961.1 - 1.9e-05 25.1 0.2 5.2e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 PH domain APH PF01636.23 KNZ77961.1 - 0.0022 18.0 3.7 0.0051 16.8 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ77961.1 - 0.016 14.2 0.2 0.03 13.4 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3915 PF13054.6 KNZ77961.1 - 0.019 14.9 10.2 0.051 13.6 10.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Pkinase_fungal PF17667.1 KNZ77961.1 - 0.029 13.2 16.9 0.36 9.6 16.8 2.1 1 1 0 1 1 1 0 Fungal protein kinase RR_TM4-6 PF06459.12 KNZ77961.1 - 0.043 13.6 10.8 0.069 13.0 10.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 KNZ77961.1 - 0.51 8.6 6.0 0.69 8.1 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 KNZ77961.1 - 4.2 7.2 12.0 0.17 11.7 6.1 1.7 2 0 0 2 2 1 0 Coilin N-terminus FAM76 PF16046.5 KNZ77961.1 - 4.8 6.5 12.4 7.8 5.8 12.4 1.2 1 0 0 1 1 1 0 FAM76 protein Connexin PF00029.19 KNZ77961.1 - 5.6 6.7 6.0 13 5.4 6.0 1.5 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 KNZ77961.1 - 7.6 5.2 10.2 11 4.6 10.2 1.2 1 0 0 1 1 1 0 Presenilin FoP_duplication PF13865.6 KNZ77962.1 - 0.61 10.7 10.7 0.26 11.9 7.2 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Usp PF00582.26 KNZ77963.1 - 0.1 13.1 0.7 0.19 12.3 0.2 2.0 2 1 0 2 2 2 0 Universal stress protein family IBR PF01485.21 KNZ77964.1 - 1.6e-09 37.9 24.2 4.5e-07 30.0 12.7 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Amidase PF01425.21 KNZ77966.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Amidase Phosphorylase PF00343.20 KNZ77967.1 - 2.2e-303 1008.0 0.0 2.6e-303 1007.8 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF1708 PF08101.11 KNZ77968.1 - 5.1e-18 65.4 0.0 8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) STE PF02200.16 KNZ77969.1 - 5.1e-54 181.4 0.0 8.6e-54 180.6 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KNZ77969.1 - 3.8e-11 42.8 11.3 4.7e-06 26.7 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ77969.1 - 4.1e-09 36.5 8.5 0.00011 22.8 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ77969.1 - 1.3e-08 34.9 13.6 3.4e-08 33.6 4.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KNZ77969.1 - 3.8e-05 23.9 3.0 0.018 15.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KNZ77969.1 - 0.00052 19.9 0.5 0.00052 19.9 0.5 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HE PF16278.5 KNZ77969.1 - 0.0073 16.7 7.6 0.081 13.4 1.4 2.7 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_8 PF15909.5 KNZ77969.1 - 0.0082 16.4 1.2 0.02 15.2 1.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 KNZ77969.1 - 0.015 15.6 1.6 0.025 14.8 1.6 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 KNZ77969.1 - 0.16 12.4 5.3 0.69 10.4 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 KNZ77969.1 - 0.25 11.1 12.2 0.085 12.6 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 KNZ77969.1 - 0.98 9.8 3.8 6.6 7.1 3.8 2.1 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Pilin_N PF07790.11 KNZ77970.1 - 0.0097 16.8 1.5 0.012 16.5 0.2 1.8 2 0 0 2 2 2 1 Archaeal Type IV pilin, N-terminal MSP1a PF11670.8 KNZ77970.1 - 0.071 12.4 4.0 0.092 12.0 4.0 1.2 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF515 PF04415.12 KNZ77970.1 - 2.2 6.6 3.7 2.9 6.2 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Herpes_gE PF02480.16 KNZ77971.1 - 0.00023 20.1 0.0 0.00033 19.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 KNZ77971.1 - 0.005 17.7 0.0 0.008 17.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF5305 PF17231.2 KNZ77971.1 - 0.073 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Cas_csx3 PF09620.10 KNZ77971.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) SRP9-21 PF05486.12 KNZ77972.1 - 2.5e-10 40.6 2.3 9.4e-09 35.6 2.3 2.3 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Pou PF00157.17 KNZ77972.1 - 0.05 13.6 0.1 0.068 13.2 0.1 1.2 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Mito_carr PF00153.27 KNZ77973.1 - 2.8e-59 197.0 2.5 1.9e-21 75.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 KNZ77974.1 - 2.9e-43 148.1 0.0 4.9e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ77974.1 - 7.1e-39 133.6 0.0 1.1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ77974.1 - 0.0049 16.8 0.3 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ77974.1 - 0.05 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ77974.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Rhodanese PF00581.20 KNZ77975.1 - 3.7e-08 33.8 0.0 1.1e-07 32.3 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain DUF1687 PF07955.11 KNZ77976.1 - 5.6e-15 55.9 0.0 1.6e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) RNase_T PF00929.24 KNZ77976.1 - 0.0093 16.5 0.9 0.058 13.9 0.9 2.1 1 1 0 1 1 1 1 Exonuclease Aldolase_II PF00596.21 KNZ77977.1 - 5.3e-43 147.1 0.1 7e-43 146.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Phosphoesterase PF04185.14 KNZ77978.1 - 1.1e-34 120.2 1.2 9.7e-34 117.1 1.2 1.9 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KNZ77978.1 - 0.0058 16.1 0.2 0.0075 15.7 0.2 1.2 1 0 0 1 1 1 1 Sulfatase SNF2_N PF00176.23 KNZ77979.1 - 5.7e-42 143.7 0.5 9.5e-42 143.0 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ApoO PF09769.9 KNZ77979.1 - 5.8e-26 91.0 0.0 1.5e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Apolipoprotein O Helicase_C PF00271.31 KNZ77979.1 - 1.2e-17 64.3 0.0 1.2e-16 61.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KNZ77979.1 - 2.4e-05 23.6 0.0 7.9e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 KNZ77979.1 - 0.0031 17.4 6.9 0.0031 17.4 6.9 2.9 2 1 1 3 3 3 1 PHD-finger Imm52 PF15579.6 KNZ77979.1 - 0.033 14.1 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 52 Uds1 PF15456.6 KNZ77979.1 - 4.4 7.5 9.3 2.4 8.4 0.2 3.1 3 0 0 3 3 3 0 Up-regulated During Septation DUF3638 PF12340.8 KNZ77980.1 - 2.2e-79 266.0 0.1 3.8e-79 265.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KNZ77980.1 - 9.5e-15 53.7 0.0 2.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Dynamitin PF04912.14 KNZ77980.1 - 0.0016 17.9 0.2 0.0034 16.8 0.2 1.5 1 0 0 1 1 1 1 Dynamitin DUF3584 PF12128.8 KNZ77980.1 - 2.2 5.7 5.0 0.36 8.3 1.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF3638 PF12340.8 KNZ77981.1 - 1.9e-84 282.6 0.1 3.6e-84 281.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 KNZ77981.1 - 5.1e-15 54.6 0.4 1.4e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3645) PCMT PF01135.19 KNZ77981.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RVP_2 PF08284.11 KNZ77982.1 - 0.025 14.4 0.1 0.062 13.1 0.1 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KNZ77983.1 - 0.00045 20.7 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ77983.1 - 0.0027 18.3 0.0 0.0063 17.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Med3 PF11593.8 KNZ77984.1 - 0.17 11.1 3.9 2.2 7.4 3.9 2.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal NAD_binding_4 PF07993.12 KNZ77985.1 - 3.6e-25 88.6 0.0 5.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ77985.1 - 8.1e-20 70.8 0.0 1.2e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KNZ77985.1 - 1.5e-08 34.4 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ77985.1 - 0.00041 20.3 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KNZ77985.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein p450 PF00067.22 KNZ77986.1 - 2.2e-16 59.7 0.0 2.7e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NUP PF06516.11 KNZ77987.1 - 2.4e-107 358.8 0.0 3e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Acyl_transf_1 PF00698.21 KNZ77989.1 - 0.32 10.5 0.7 0.45 10.0 0.7 1.2 1 0 0 1 1 1 0 Acyl transferase domain Coat_X PF07552.11 KNZ77990.1 - 0.095 12.5 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 Spore Coat Protein X and V domain zf-C3HC4_3 PF13920.6 KNZ77994.1 - 2.6e-14 52.8 17.7 1.4e-13 50.5 6.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ77994.1 - 4.9e-10 39.1 6.1 4.9e-10 39.1 6.1 2.7 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 FYVE PF01363.21 KNZ77994.1 - 9.4e-08 32.1 6.7 9.4e-08 32.1 6.7 2.8 2 1 1 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 KNZ77994.1 - 3.5e-07 30.5 5.5 3.5e-07 30.5 5.5 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KNZ77994.1 - 4.6e-05 23.2 6.6 4.6e-05 23.2 6.6 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 KNZ77994.1 - 0.0003 21.0 3.9 0.0003 21.0 3.9 3.2 3 0 0 3 3 3 1 FYVE-type zinc finger zf-C3HC4_2 PF13923.6 KNZ77994.1 - 0.0016 18.3 6.5 0.0016 18.3 6.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KNZ77994.1 - 0.0031 17.2 2.7 0.0031 17.2 2.7 2.6 2 0 0 2 2 2 1 P-11 zinc finger Rho_N PF07498.12 KNZ77994.1 - 0.016 15.1 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Armet PF10208.9 KNZ77994.1 - 0.023 14.6 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding DUF4518 PF15008.6 KNZ77994.1 - 0.045 12.9 0.1 9 5.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) DUF4746 PF15928.5 KNZ77994.1 - 0.63 9.4 4.8 0.91 8.9 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF501 PF04417.12 KNZ77994.1 - 0.94 9.3 5.3 1.8 8.4 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) zf-RING_5 PF14634.6 KNZ77994.1 - 1.2 9.1 21.5 0.048 13.6 5.1 2.8 2 0 0 2 2 2 0 zinc-RING finger domain Presenilin PF01080.17 KNZ77994.1 - 2.6 6.7 4.5 4.4 6.0 4.5 1.3 1 0 0 1 1 1 0 Presenilin zf-UDP PF14569.6 KNZ77994.1 - 2.9 8.1 13.6 4.4 7.5 1.8 3.0 2 1 0 2 2 2 0 Zinc-binding RING-finger DUF3395 PF11875.8 KNZ77994.1 - 3.9 7.3 7.9 7.4 6.4 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) zf-MYND PF01753.18 KNZ77995.1 - 2.2e-08 34.1 10.2 3.4e-08 33.4 10.2 1.3 1 0 0 1 1 1 1 MYND finger TPR_2 PF07719.17 KNZ77995.1 - 0.0043 17.1 2.0 0.5 10.6 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ77995.1 - 0.041 14.2 1.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 KNZ77995.1 - 0.043 13.9 0.5 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 KNZ77995.1 - 0.48 10.8 1.7 24 5.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 KNZ77995.1 - 0.71 10.2 6.9 1.3 9.4 6.9 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CHCH PF06747.13 KNZ77996.1 - 0.0029 17.7 3.1 0.0043 17.1 2.2 1.7 1 1 1 2 2 2 2 CHCH domain MBA1 PF07961.11 KNZ77997.1 - 8.9e-07 28.2 0.0 1.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KNZ77997.1 - 0.0075 16.4 1.7 2 8.5 0.1 3.0 2 2 1 3 3 3 2 Tim44-like domain DASH_Dad3 PF08656.10 KNZ77997.1 - 0.13 12.3 0.5 0.28 11.3 0.5 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 Terpene_synth_C PF03936.16 KNZ77998.1 - 5.8e-07 29.1 0.0 9.6e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain SPOB_ab PF14682.6 KNZ77998.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal MFS_1 PF07690.16 KNZ77999.1 - 2.9e-24 85.7 29.0 4.6e-20 71.9 7.1 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ77999.1 - 2.2e-06 26.8 11.5 2.2e-06 26.8 11.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2160 PF09928.9 KNZ77999.1 - 0.035 14.4 1.9 0.5 10.7 0.0 2.8 2 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) MFS_1_like PF12832.7 KNZ77999.1 - 0.077 11.8 22.2 0.92 8.3 12.3 2.5 2 1 0 2 2 2 0 MFS_1 like family DEAD PF00270.29 KNZ78000.1 - 3.9e-39 134.2 0.0 8.5e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78000.1 - 9.6e-27 93.5 0.0 4.3e-24 85.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78000.1 - 0.00012 22.1 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KNZ78000.1 - 0.088 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.6 KNZ78000.1 - 0.41 10.9 1.8 4.1 7.7 1.8 2.5 1 1 0 1 1 1 0 AAA domain NDUF_B7 PF05676.13 KNZ78001.1 - 1.8e-31 107.6 3.2 2.1e-31 107.4 3.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 KNZ78001.1 - 0.0082 16.1 2.1 0.011 15.7 2.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.32 KNZ78002.1 - 1.4e-42 142.8 24.6 3.1e-08 34.1 0.2 12.4 13 0 0 13 13 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78002.1 - 3.1e-26 91.5 0.0 0.00072 19.8 0.0 10.0 4 2 3 10 10 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KNZ78002.1 - 9.7e-20 70.9 0.0 1.5e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KNZ78002.1 - 2.3e-11 43.2 3.6 0.027 13.4 0.0 6.7 4 2 3 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ78002.1 - 1.1e-06 28.7 0.1 1 9.2 0.1 4.7 3 2 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KNZ78002.1 - 1.2e-06 28.0 0.0 0.29 10.4 0.0 4.5 4 1 2 6 6 6 2 WD40-like domain PD40 PF07676.12 KNZ78002.1 - 6.3e-05 22.8 1.6 2.2 8.3 0.0 6.6 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 KNZ78002.1 - 0.012 14.9 0.0 0.48 9.6 0.0 3.6 5 2 2 7 7 7 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 KNZ78002.1 - 0.019 13.6 0.0 0.073 11.7 0.0 1.9 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Cytochrom_D1 PF02239.16 KNZ78002.1 - 0.045 12.3 2.4 8.3 4.8 0.1 4.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain DPPIV_N PF00930.21 KNZ78002.1 - 0.064 12.0 0.1 0.46 9.2 0.0 2.5 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.11 KNZ78002.1 - 0.089 11.9 0.1 9.3 5.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) Sdh5 PF03937.16 KNZ78003.1 - 1.1e-28 98.9 0.4 1.4e-28 98.6 0.4 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase O-FucT PF10250.9 KNZ78006.1 - 1.5e-12 47.9 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Gly_transf_sug PF04488.15 KNZ78007.1 - 2.2e-07 31.4 0.1 3.5e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KNZ78007.1 - 5.9e-05 22.6 0.1 8.3e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DEAD PF00270.29 KNZ78008.1 - 5.4e-44 150.0 0.2 8.4e-44 149.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78008.1 - 1.9e-27 95.8 0.8 5.5e-27 94.3 0.4 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KNZ78008.1 - 0.0053 16.1 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit QSregVF PF13652.6 KNZ78008.1 - 0.085 12.9 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor QLQ PF08880.11 KNZ78010.1 - 0.045 13.5 0.0 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 QLQ PIF1 PF05970.14 KNZ78013.1 - 2.7e-33 115.6 0.0 3.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ78013.1 - 0.0036 17.0 0.0 0.0082 15.8 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Herpes_Helicase PF02689.14 KNZ78014.1 - 6.3e-06 24.4 0.0 6.5e-06 24.4 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ78014.1 - 0.049 13.5 0.2 0.12 12.3 0.1 1.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain ATG11 PF10377.9 KNZ78015.1 - 6.7e-32 110.3 0.9 6.2e-31 107.1 0.0 2.7 2 0 0 2 2 2 1 Autophagy-related protein 11 Fez1 PF06818.15 KNZ78015.1 - 0.12 12.8 0.1 0.12 12.8 0.1 4.3 3 1 1 4 4 4 0 Fez1 DUF1664 PF07889.12 KNZ78015.1 - 2.2 8.3 25.1 5.8 7.0 3.9 5.3 2 1 2 5 5 5 0 Protein of unknown function (DUF1664) LELP1 PF15042.6 KNZ78015.1 - 2.3 8.7 11.3 0.28 11.6 6.3 1.9 1 1 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 IFP_35_N PF07334.13 KNZ78015.1 - 3.7 7.7 9.8 4.7 7.4 1.3 3.7 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Sugar_tr PF00083.24 KNZ78016.1 - 1.3e-89 301.1 17.0 1.6e-89 300.9 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ78016.1 - 1.2e-27 96.8 39.1 2.8e-25 89.0 23.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4040 PF13244.6 KNZ78016.1 - 0.67 10.1 8.3 0.56 10.4 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Metallophos PF00149.28 KNZ78017.1 - 3.2e-40 138.8 0.1 4.1e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KNZ78017.1 - 9.7e-22 77.2 0.5 2e-21 76.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain PH_9 PF15410.6 KNZ78018.1 - 5.1e-06 26.8 0.0 0.017 15.5 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 KNZ78018.1 - 0.00072 20.0 0.1 0.31 11.6 0.0 2.9 3 0 0 3 3 3 2 PH domain ThylakoidFormat PF11264.8 KNZ78021.1 - 0.19 11.4 0.2 0.27 10.9 0.2 1.1 1 0 0 1 1 1 0 Thylakoid formation protein HAD_2 PF13419.6 KNZ78022.1 - 0.022 14.9 0.0 0.15 12.1 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase UTRA PF07702.13 KNZ78022.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 UTRA domain RNA_pol_N PF01194.17 KNZ78023.1 - 7.3e-31 106.3 0.3 8.4e-31 106.1 0.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Mu-like_Com PF10122.9 KNZ78023.1 - 0.054 12.9 0.6 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com EF-hand_4 PF12763.7 KNZ78024.1 - 3.1e-15 56.0 0.0 1.5e-09 37.7 0.0 3.0 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KNZ78024.1 - 4.5e-06 27.0 2.9 0.00027 21.3 0.2 3.7 3 1 0 3 3 3 1 EF-hand domain pair KASH_CCD PF14662.6 KNZ78024.1 - 0.00015 21.7 56.1 0.036 13.9 12.7 3.6 1 1 1 3 3 3 3 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 KNZ78024.1 - 0.003 17.4 1.8 0.003 17.4 1.8 4.7 1 1 2 4 4 4 3 Phage minor structural protein GP20 DUF2848 PF11010.8 KNZ78024.1 - 0.031 13.9 0.4 0.09 12.4 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2848) BLOC1_2 PF10046.9 KNZ78024.1 - 0.033 14.5 35.6 2.5 8.5 0.9 5.5 2 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_1 PF00036.32 KNZ78024.1 - 0.046 13.3 0.2 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 EF hand FapA PF03961.13 KNZ78024.1 - 0.052 12.2 28.7 0.83 8.2 12.0 2.8 1 1 2 3 3 3 0 Flagellar Assembly Protein A GAS PF13851.6 KNZ78024.1 - 0.12 11.8 49.3 0.32 10.3 8.5 4.7 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Myc-LZ PF02344.15 KNZ78024.1 - 0.19 11.8 0.1 0.19 11.8 0.1 4.3 3 0 0 3 3 3 0 Myc leucine zipper domain EF-hand_6 PF13405.6 KNZ78024.1 - 0.28 11.2 2.6 27 5.1 0.1 3.6 3 0 0 3 3 3 0 EF-hand domain DUF1319 PF07028.11 KNZ78024.1 - 1.3 9.3 29.3 0.21 11.8 2.5 5.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1319) Shugoshin_N PF07558.11 KNZ78024.1 - 1.5 8.8 32.1 0.68 9.9 0.4 6.3 6 0 0 6 6 6 0 Shugoshin N-terminal coiled-coil region Uso1_p115_C PF04871.13 KNZ78024.1 - 2.2 8.7 41.4 1.6 9.1 9.7 5.1 2 1 3 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4686 PF15742.5 KNZ78024.1 - 5.6 6.0 51.5 0.38 9.8 6.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4686) MAD PF05557.13 KNZ78024.1 - 9.3 4.5 49.7 0.052 11.9 12.1 3.1 1 1 0 2 2 1 0 Mitotic checkpoint protein HMG_box PF00505.19 KNZ78025.1 - 1.1e-11 45.0 0.6 1.2e-10 41.6 0.1 2.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ78025.1 - 0.056 14.1 0.1 0.16 12.6 0.1 1.8 1 0 0 1 1 1 0 HMG-box domain Sec2p PF06428.11 KNZ78026.1 - 9.2e-15 54.4 10.7 9.2e-15 54.4 10.7 2.3 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p CC2-LZ PF16516.5 KNZ78026.1 - 0.1 13.0 17.0 0.97 9.8 6.2 2.9 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator XhlA PF10779.9 KNZ78026.1 - 0.59 10.4 6.6 8.7 6.6 0.6 3.1 2 1 1 3 3 3 0 Haemolysin XhlA DUF1993 PF09351.10 KNZ78026.1 - 1.1 9.4 9.8 0.37 10.9 7.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Spc7 PF08317.11 KNZ78026.1 - 1.1 8.1 20.8 0.38 9.6 16.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 KNZ78026.1 - 1.9 7.0 13.6 1.1 7.8 10.6 1.7 1 1 1 2 2 2 0 AAA domain Herpes_UL6 PF01763.16 KNZ78026.1 - 3 6.2 12.6 0.24 9.8 2.4 2.0 1 1 1 2 2 2 0 Herpesvirus UL6 like Tropomyosin PF00261.20 KNZ78026.1 - 4.3 6.6 25.4 0.25 10.7 9.7 2.5 1 1 1 2 2 2 0 Tropomyosin HIP1_clath_bdg PF16515.5 KNZ78026.1 - 6.2 7.5 22.0 1.5 9.5 1.8 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DFP PF04127.15 KNZ78027.1 - 1.4e-17 64.1 0.0 3.2e-07 30.4 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Pkinase PF00069.25 KNZ78028.1 - 5.6e-31 107.9 0.0 8.1e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78028.1 - 1.5e-16 60.5 0.0 1.9e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KNZ78028.1 - 0.00024 20.2 0.1 0.00035 19.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KNZ78028.1 - 0.00053 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ78028.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TENA_THI-4 PF03070.16 KNZ78029.1 - 1.2e-07 31.8 0.1 1.5e-07 31.5 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Zn_clus PF00172.18 KNZ78030.1 - 1.5e-05 25.0 9.4 2.8e-05 24.2 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KNZ78030.1 - 0.00049 20.1 0.0 0.0076 16.2 0.0 2.7 3 0 0 3 3 3 1 PAS fold ORC6 PF05460.13 KNZ78030.1 - 0.041 13.2 0.9 0.063 12.5 0.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ATF7IP_BD PF16788.5 KNZ78030.1 - 8.5 6.4 7.1 17 5.4 7.1 1.4 1 0 0 1 1 1 0 ATF-interacting protein binding domain Formyl_trans_N PF00551.19 KNZ78031.1 - 1.5e-20 73.7 0.0 2.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 KNZ78031.1 - 2.7e-10 40.4 0.0 4.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain RSN1_7TM PF02714.15 KNZ78034.1 - 6.3e-83 278.2 23.7 1e-82 277.6 23.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KNZ78034.1 - 1.2e-40 138.8 4.2 1.2e-40 138.8 4.2 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KNZ78034.1 - 1e-33 117.0 0.0 1.5e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KNZ78034.1 - 6.5e-12 45.5 0.0 1.4e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF155 PF02582.14 KNZ78035.1 - 8.1e-47 159.6 0.0 1.4e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RmlD_sub_bind PF04321.17 KNZ78036.1 - 1.4e-29 103.1 0.0 1.9e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain RNase_H PF00075.24 KNZ78036.1 - 7.7e-07 29.4 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 RNase H Epimerase PF01370.21 KNZ78036.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Nairo_nucleo PF02477.15 KNZ78036.1 - 0.077 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein Imm_superinfect PF14373.6 KNZ78037.1 - 0.29 11.1 1.1 0.58 10.1 1.1 1.5 1 0 0 1 1 1 0 Superinfection immunity protein Helitron_like_N PF14214.6 KNZ78040.1 - 1.6e-64 217.7 0.1 2.7e-64 216.9 0.1 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ78040.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) His_Phos_2 PF00328.22 KNZ78044.1 - 1e-91 308.2 0.1 1.3e-91 307.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KNZ78044.1 - 2.3e-34 117.4 0.0 6.7e-34 115.9 0.0 1.9 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KNZ78044.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Chromo PF00385.24 KNZ78045.1 - 1e-16 60.5 0.1 1.2e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Stomagen PF16851.5 KNZ78047.1 - 1.6 8.8 9.4 7.2 6.7 4.3 2.5 2 0 0 2 2 2 0 Stomagen RasGAP PF00616.19 KNZ78048.1 - 3.9e-40 137.8 0.1 7.7e-40 136.8 0.1 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KNZ78048.1 - 1.9e-24 86.4 0.5 4.1e-12 46.4 0.0 3.0 1 1 1 2 2 2 2 RasGAP C-terminus CH PF00307.31 KNZ78048.1 - 1.1e-14 54.5 0.0 3.5e-14 52.9 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 KNZ78048.1 - 1.4e-13 49.4 26.3 0.015 15.0 0.2 9.4 9 0 0 9 9 9 6 IQ calmodulin-binding motif MFS_1 PF07690.16 KNZ78049.1 - 1.2e-10 40.8 16.6 7.7e-10 38.2 16.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4491 PF14898.6 KNZ78049.1 - 2.8 8.5 5.3 0.47 10.9 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) zf-RVT PF13966.6 KNZ78050.1 - 2.3e-05 25.0 1.5 4.7e-05 24.0 1.5 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase E1-E2_ATPase PF00122.20 KNZ78051.1 - 1.3e-47 161.6 0.1 3.2e-47 160.4 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KNZ78051.1 - 8.6e-33 114.4 0.0 1.4e-32 113.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KNZ78051.1 - 1.8e-18 66.8 2.9 6.7e-08 32.9 0.7 4.0 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KNZ78051.1 - 0.00093 19.0 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KNZ78051.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-CHY PF05495.12 KNZ78051.1 - 0.45 11.0 8.7 0.1 13.1 3.2 2.3 2 0 0 2 2 2 0 CHY zinc finger ABC_tran PF00005.27 KNZ78053.1 - 1.3e-15 58.1 0.0 4.7e-15 56.3 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KNZ78053.1 - 3.4e-08 33.7 5.0 6.8e-06 26.1 0.0 2.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KNZ78053.1 - 0.001 18.8 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KNZ78053.1 - 0.0019 18.2 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 KNZ78053.1 - 0.0019 18.7 0.1 0.0035 17.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 KNZ78053.1 - 0.0054 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KNZ78053.1 - 0.0059 16.1 0.6 0.27 10.6 0.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KNZ78053.1 - 0.0096 15.7 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KNZ78053.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KNZ78053.1 - 0.065 13.3 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 KNZ78053.1 - 0.07 12.8 0.0 0.074 12.7 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_27 PF13514.6 KNZ78053.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 KNZ78053.1 - 0.1 11.3 0.8 0.33 9.7 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class eIF3g PF12353.8 KNZ78053.1 - 0.13 12.6 0.3 0.3 11.5 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Arf PF00025.21 KNZ78053.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family zf-CCHC_6 PF15288.6 KNZ78053.1 - 0.18 11.6 1.0 0.35 10.7 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle FtsK_SpoIIIE PF01580.18 KNZ78053.1 - 0.19 11.1 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 KNZ78053.1 - 0.21 11.5 0.2 0.39 10.6 0.2 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 KNZ78053.1 - 0.25 11.0 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Opy2 PF09463.10 KNZ78054.1 - 0.0099 16.2 17.5 0.016 15.5 17.5 1.4 1 0 0 1 1 1 1 Opy2 protein DUF3818 PF12825.7 KNZ78056.1 - 2e-131 438.0 0.4 2.8e-131 437.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KNZ78056.1 - 8.1e-34 116.4 0.1 2e-33 115.2 0.1 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KNZ78056.1 - 4e-10 39.7 0.3 8.6e-09 35.4 0.0 3.0 3 0 0 3 3 3 1 PX domain CDC45 PF02724.14 KNZ78056.1 - 3 6.0 6.5 5.9 5.1 6.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Chromo PF00385.24 KNZ78057.1 - 6.7e-09 35.5 0.2 1.2e-08 34.7 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 KNZ78060.1 - 0.034 14.8 0.0 0.31 11.7 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KNZ78060.1 - 0.05 14.2 0.0 0.22 12.1 0.0 1.9 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF5560 PF17715.1 KNZ78060.1 - 1.1 8.7 4.2 0.98 8.8 1.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5560) DEAD PF00270.29 KNZ78062.1 - 1.2e-35 122.9 0.0 2.5e-35 121.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 KNZ78062.1 - 1.2e-21 76.7 0.0 2.6e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 KNZ78062.1 - 1e-19 70.9 0.0 3.6e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78062.1 - 0.00014 21.9 0.2 0.00036 20.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KNZ78062.1 - 0.012 15.1 1.2 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Pkinase PF00069.25 KNZ78063.1 - 3.8e-61 206.8 0.0 2.9e-40 138.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78063.1 - 5.4e-25 88.2 0.3 3.8e-18 65.7 0.1 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ78063.1 - 2.7e-07 29.9 0.1 3.8e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KNZ78063.1 - 3.8e-05 23.1 0.6 0.00042 19.7 0.0 2.4 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ78063.1 - 9.6e-05 22.4 0.4 0.019 14.9 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ78063.1 - 0.00062 19.2 0.1 0.007 15.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KNZ78063.1 - 0.032 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KNZ78063.1 - 0.035 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_C PF00433.24 KNZ78063.1 - 0.044 14.5 0.6 0.12 13.1 0.6 1.8 1 0 0 1 1 1 0 Protein kinase C terminal domain Seadorna_VP7 PF07387.11 KNZ78063.1 - 0.057 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 KNZ78063.1 - 0.077 11.8 0.2 0.15 10.8 0.1 1.3 1 1 0 1 1 1 0 Fungal protein kinase BCDHK_Adom3 PF10436.9 KNZ78065.1 - 7.3e-34 117.0 0.0 1.3e-33 116.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KNZ78065.1 - 0.00014 22.3 0.0 0.0047 17.4 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SCHIP-1 PF10148.9 KNZ78066.1 - 0.029 14.0 0.3 0.031 13.9 0.3 1.0 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 DUF2786 PF10979.8 KNZ78066.1 - 0.063 13.2 2.5 0.11 12.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Retrotran_gag_2 PF14223.6 KNZ78067.1 - 6.3e-10 38.9 0.1 6.3e-10 38.9 0.1 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type RT_RNaseH PF17917.1 KNZ78068.1 - 2e-08 34.4 0.0 4.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78068.1 - 5.3e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase POT1PC PF16686.5 KNZ78068.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein DUF3123 PF11321.8 KNZ78069.1 - 1 10.0 5.2 2.3 8.9 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) WD40 PF00400.32 KNZ78071.1 - 7.9e-125 403.1 92.8 1.3e-10 41.7 2.2 14.3 14 0 0 14 14 14 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78071.1 - 1.4e-35 121.4 8.1 0.051 13.9 0.0 13.2 1 1 12 13 13 13 12 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KNZ78071.1 - 5e-22 77.9 0.9 0.43 8.8 0.0 11.4 1 1 10 12 12 12 10 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KNZ78071.1 - 1.5e-19 69.4 1.0 17 5.5 0.0 13.2 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 KNZ78071.1 - 5.7e-19 68.6 15.0 2.4e-05 24.1 4.1 7.0 1 1 4 5 5 5 5 PQQ-like domain Ge1_WD40 PF16529.5 KNZ78071.1 - 5e-16 58.6 29.5 0.059 12.3 0.0 12.3 1 1 12 13 13 13 7 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KNZ78071.1 - 4.1e-15 55.9 3.4 0.14 11.5 0.0 7.8 5 4 2 7 7 7 5 WD40-like domain NACHT PF05729.12 KNZ78071.1 - 2.3e-10 40.6 0.1 7e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KNZ78071.1 - 3.6e-06 27.5 0.1 3.8e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KNZ78071.1 - 3.7e-06 25.7 0.6 3.6 6.0 0.0 5.6 1 1 5 6 6 6 2 Cytochrome D1 heme domain PQQ PF01011.21 KNZ78071.1 - 3.3e-05 23.6 0.0 1.2e+02 2.9 0.0 7.9 10 0 0 10 10 9 0 PQQ enzyme repeat APS_kinase PF01583.20 KNZ78071.1 - 0.0007 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF3244 PF11589.8 KNZ78071.1 - 0.0042 17.1 0.0 91 3.2 0.0 5.3 4 1 1 5 5 5 0 Domain of unknown function (DUF3244) AAA_22 PF13401.6 KNZ78071.1 - 0.0057 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KNZ78071.1 - 0.012 15.3 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.29 KNZ78071.1 - 0.026 14.9 0.0 0.12 12.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KNZ78071.1 - 0.034 14.1 2.2 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 KNZ78071.1 - 0.037 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KNZ78071.1 - 0.088 13.2 0.0 0.33 11.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KNZ78071.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KNZ78071.1 - 0.15 12.6 0.0 0.64 10.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain Cytidylate_kin PF02224.18 KNZ78071.1 - 0.18 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase ABC_tran PF00005.27 KNZ78071.1 - 0.18 12.3 0.3 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KNZ78071.1 - 0.71 10.3 3.1 1 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain PP1_inhibitor PF05361.12 KNZ78072.1 - 0.0061 16.6 0.5 0.013 15.5 0.5 1.5 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor Suf PF05843.14 KNZ78072.1 - 0.015 15.3 2.1 0.03 14.3 2.1 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HAUS-augmin3 PF14932.6 KNZ78072.1 - 0.023 14.3 3.2 0.042 13.4 3.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TelA PF05816.11 KNZ78072.1 - 0.14 11.2 2.4 0.22 10.5 2.4 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Pol_alpha_B_N PF08418.10 KNZ78072.1 - 7.5 6.4 10.1 4.7 7.1 0.8 2.4 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Syndecan PF01034.20 KNZ78073.1 - 0.18 11.7 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KNZ78073.1 - 0.19 11.5 0.2 0.42 10.4 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PIF1 PF05970.14 KNZ78074.1 - 1.2e-55 189.2 0.1 1.4e-55 189.0 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ78074.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ78074.1 - 0.055 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helitron_like_N PF14214.6 KNZ78075.1 - 2.5e-60 204.0 0.2 3.8e-60 203.4 0.2 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ78075.1 - 0.00066 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Bacteriophage replication gene A protein (GPA) WD40 PF00400.32 KNZ78077.1 - 1.6e-59 196.5 38.8 4.9e-10 39.8 0.4 7.0 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78077.1 - 2.2e-11 43.9 5.7 0.12 12.7 0.0 6.3 2 1 5 7 7 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ78077.1 - 4.7e-09 35.7 10.5 0.069 12.1 0.0 6.4 2 1 5 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KNZ78077.1 - 2.4e-08 34.1 0.0 9.5e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Frtz PF11768.8 KNZ78077.1 - 7.3e-08 31.2 0.2 0.031 12.6 0.0 4.4 1 1 4 5 5 5 4 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 KNZ78077.1 - 7.7e-08 32.1 1.2 13 5.8 0.0 6.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 KNZ78077.1 - 2.6e-06 27.9 0.1 4e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain WD40_like PF17005.5 KNZ78077.1 - 3e-05 23.5 0.1 0.022 14.1 0.0 3.1 1 1 0 2 2 2 1 WD40-like domain APS_kinase PF01583.20 KNZ78077.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 KNZ78077.1 - 0.00087 19.7 0.0 0.0083 16.5 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytochrom_D1 PF02239.16 KNZ78077.1 - 0.0017 17.0 0.4 0.3 9.6 0.0 3.0 1 1 2 3 3 3 1 Cytochrome D1 heme domain AAA_22 PF13401.6 KNZ78077.1 - 0.0026 18.0 0.0 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KNZ78077.1 - 0.0067 16.1 0.0 0.086 12.6 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 KNZ78077.1 - 0.0075 16.2 1.3 1.8 8.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain PQQ_2 PF13360.6 KNZ78077.1 - 0.01 15.5 4.7 0.13 11.8 4.8 2.5 1 1 0 1 1 1 0 PQQ-like domain ATPase_2 PF01637.18 KNZ78077.1 - 0.015 15.2 0.1 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KNZ78077.1 - 0.016 15.7 0.0 0.49 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KNZ78077.1 - 0.023 13.9 0.0 0.066 12.4 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KNZ78077.1 - 0.056 13.8 0.0 0.25 11.7 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KNZ78077.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KNZ78077.1 - 0.12 12.9 1.1 0.99 9.9 0.0 2.7 3 0 0 3 3 3 0 ABC transporter Cytidylate_kin PF02224.18 KNZ78077.1 - 0.12 12.1 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 KNZ78077.1 - 0.32 11.5 4.1 1.4 9.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain Gly-zipper_Omp PF13488.6 KNZ78078.1 - 0.0047 16.9 0.7 0.0047 16.9 0.7 4.0 3 1 1 4 4 4 1 Glycine zipper Adeno_E3_CR2 PF02439.15 KNZ78078.1 - 0.027 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MTS PF05175.14 KNZ78078.1 - 0.088 12.4 0.1 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain ISET-FN3_linker PF16625.5 KNZ78078.1 - 4 8.0 6.2 14 6.3 0.5 3.0 3 0 0 3 3 3 0 Unstructured linking region I-set and fnIII on Brother of CDO WD40 PF00400.32 KNZ78079.1 - 2.9e-146 471.0 108.1 2.2e-10 41.0 0.1 17.1 16 0 0 16 16 16 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78079.1 - 5.5e-36 122.7 19.5 0.0088 16.3 0.0 15.2 2 1 14 16 16 15 12 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ78079.1 - 3.1e-21 74.8 3.2 25 4.9 0.0 15.1 15 0 0 15 15 15 0 WD40-like Beta Propeller Repeat Frtz PF11768.8 KNZ78079.1 - 4e-21 74.9 3.3 0.1 10.9 0.0 10.0 2 1 9 11 11 11 9 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KNZ78079.1 - 1.5e-20 73.5 33.2 0.13 11.2 0.0 15.0 1 1 14 15 15 15 10 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KNZ78079.1 - 8.9e-16 58.1 2.2 0.0061 15.9 0.0 8.6 3 2 2 9 9 9 4 WD40-like domain PQQ_2 PF13360.6 KNZ78079.1 - 6.2e-11 42.3 23.4 0.00022 20.9 1.2 5.8 1 1 4 5 5 5 5 PQQ-like domain NACHT PF05729.12 KNZ78079.1 - 8.7e-11 42.0 0.0 2.6e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KNZ78079.1 - 1.6e-06 28.6 0.0 1.7e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 KNZ78079.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF727 PF05303.12 KNZ78079.1 - 0.0016 18.5 0.0 48 4.1 0.0 6.5 3 2 6 10 10 10 0 Protein of unknown function (DUF727) AAA_22 PF13401.6 KNZ78079.1 - 0.0017 18.6 0.0 0.0051 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KNZ78079.1 - 0.024 14.4 0.0 0.15 11.9 0.0 2.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KNZ78079.1 - 0.034 13.3 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 KNZ78079.1 - 0.038 13.9 1.7 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 KNZ78079.1 - 0.043 14.2 0.0 0.18 12.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KNZ78079.1 - 0.048 14.2 0.0 0.36 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ78079.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ78079.1 - 0.15 11.6 0.0 0.4 10.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KNZ78079.1 - 0.61 10.6 4.3 1.4 9.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain POT1PC PF16686.5 KNZ78081.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Asp_protease_2 PF13650.6 KNZ78082.1 - 0.00014 22.4 0.0 0.00016 22.2 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ78082.1 - 0.00025 21.5 0.0 0.00025 21.5 0.0 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Syndecan PF01034.20 KNZ78083.1 - 0.18 11.7 0.1 0.38 10.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 KNZ78083.1 - 0.19 11.5 0.2 0.42 10.4 0.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 WD40 PF00400.32 KNZ78084.1 - 1.1e-139 450.2 81.2 6e-11 42.7 0.3 14.7 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78084.1 - 4.5e-39 132.6 12.5 0.011 16.0 0.0 14.0 1 1 13 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ78084.1 - 3.2e-21 75.6 19.0 0.067 12.1 0.0 13.5 1 1 13 14 14 14 6 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KNZ78084.1 - 1.1e-16 60.2 13.2 8.6 6.4 0.0 14.0 14 0 0 14 14 14 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KNZ78084.1 - 5.4e-14 52.2 0.1 0.015 14.6 0.0 7.4 3 1 5 8 8 8 4 WD40-like domain PQQ_2 PF13360.6 KNZ78084.1 - 1.2e-11 44.7 18.2 0.0038 16.8 3.6 5.9 1 1 2 4 4 4 4 PQQ-like domain Frtz PF11768.8 KNZ78084.1 - 5e-11 41.6 0.0 0.53 8.5 0.0 7.3 2 2 5 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KNZ78084.1 - 7.1e-10 39.0 0.0 2.1e-09 37.5 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KNZ78084.1 - 8.3e-07 29.5 0.2 2.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Cytochrom_D1 PF02239.16 KNZ78084.1 - 5.5e-06 25.1 1.3 2.6 6.5 0.0 5.9 1 1 7 8 8 8 2 Cytochrome D1 heme domain APS_kinase PF01583.20 KNZ78084.1 - 0.0015 18.5 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.6 KNZ78084.1 - 0.012 15.4 1.1 0.11 12.2 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KNZ78084.1 - 0.031 14.0 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 KNZ78084.1 - 0.041 13.7 0.2 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 KNZ78084.1 - 0.042 14.3 0.2 0.28 11.6 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KNZ78084.1 - 0.056 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 KNZ78084.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KNZ78084.1 - 0.076 13.6 0.0 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KNZ78084.1 - 0.088 12.4 0.1 0.45 10.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KNZ78084.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain F-box-like PF12937.7 KNZ78086.1 - 1.5e-10 40.8 0.3 4.7e-10 39.2 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KNZ78086.1 - 0.055 13.9 3.6 23 5.6 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KNZ78087.1 - 4.1e-09 36.2 0.7 1.1e-08 34.8 0.7 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KNZ78087.1 - 1.9 9.0 4.2 3.1 8.3 0.3 3.2 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 KNZ78088.1 - 1.1e-28 100.0 0.0 1.4e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ78088.1 - 2.5e-13 50.1 0.0 3.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ78088.1 - 9.6e-07 28.9 0.1 1.8e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.23 KNZ78088.1 - 0.013 15.5 0.0 0.88 9.5 0.0 2.7 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 KNZ78088.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 KNZ78088.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Epimerase PF01370.21 KNZ78088.1 - 0.11 12.0 0.0 1.1 8.7 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DFP PF04127.15 KNZ78088.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Bac_rhamnosid6H PF17389.2 KNZ78089.1 - 7.2e-14 51.8 0.0 1.1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KNZ78089.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain FeoB_C PF07664.12 KNZ78090.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus Methyltransf_2 PF00891.18 KNZ78092.1 - 7.2e-22 77.7 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KNZ78092.1 - 0.061 14.1 0.0 0.41 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain APH PF01636.23 KNZ78094.1 - 5.6e-07 29.7 0.1 2.2e-06 27.7 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ78094.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ78094.1 - 0.003 17.2 0.0 0.0091 15.6 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Nif11 PF07862.11 KNZ78094.1 - 0.0032 17.7 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 Nif11 domain F-box-like PF12937.7 KNZ78095.1 - 1.4e-09 37.7 0.1 3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ78095.1 - 0.0087 15.9 0.1 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 F-box domain TMEM234 PF10639.9 KNZ78095.1 - 0.1 12.7 0.2 0.31 11.1 0.2 1.8 1 0 0 1 1 1 0 Putative transmembrane family 234 Rep_fac_C PF08542.11 KNZ78096.1 - 0.12 12.8 0.1 0.16 12.4 0.1 1.1 1 0 0 1 1 1 0 Replication factor C C-terminal domain F-box-like PF12937.7 KNZ78098.1 - 9.9e-11 41.4 2.1 1.5e-10 40.8 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KNZ78098.1 - 0.027 14.4 0.1 0.15 12.0 0.1 2.3 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 KNZ78098.1 - 0.066 13.7 9.8 20 5.8 0.0 5.6 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF4588 PF15251.6 KNZ78099.1 - 4e-06 26.8 0.9 5.2e-06 26.4 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Radial_spoke PF04712.12 KNZ78099.1 - 0.0055 15.7 0.2 0.0055 15.7 0.2 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein GOLD_2 PF13897.6 KNZ78099.1 - 0.042 14.4 0.1 0.07 13.6 0.1 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RPN2_C PF18004.1 KNZ78099.1 - 0.047 13.6 4.1 0.07 13.0 4.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3915 PF13054.6 KNZ78099.1 - 0.32 11.0 1.3 0.55 10.2 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SKG6 PF08693.10 KNZ78100.1 - 0.0017 17.7 6.1 0.0031 16.9 6.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 KNZ78100.1 - 0.0024 17.7 2.4 0.0047 16.8 2.4 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Yip1 PF04893.17 KNZ78100.1 - 0.0036 17.1 0.4 0.0036 17.1 0.4 1.5 2 0 0 2 2 2 1 Yip1 domain Adeno_E3_CR2 PF02439.15 KNZ78100.1 - 0.0045 16.7 2.7 0.0095 15.7 2.7 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF2970 PF11174.8 KNZ78100.1 - 0.033 14.0 0.3 0.08 12.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Spectrin_like PF18373.1 KNZ78100.1 - 0.036 14.1 0.2 0.071 13.2 0.2 1.4 1 0 0 1 1 1 0 Spectrin like domain TMEM154 PF15102.6 KNZ78100.1 - 0.051 13.5 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 KNZ78100.1 - 0.072 14.0 0.0 0.25 12.2 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_YMGG PF13441.6 KNZ78100.1 - 0.098 12.4 1.9 0.17 11.6 1.9 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Herpes_gE PF02480.16 KNZ78100.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.6 KNZ78100.1 - 0.22 10.3 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless VEGFR-2_TMD PF17988.1 KNZ78100.1 - 0.45 10.0 2.6 0.99 8.9 2.6 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain Syndecan PF01034.20 KNZ78100.1 - 0.64 10.0 1.9 1.2 9.1 1.9 1.4 1 0 0 1 1 1 0 Syndecan domain Tannase PF07519.11 KNZ78102.1 - 3.3e-102 342.8 0.0 4.2e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KNZ78102.1 - 0.00034 20.0 0.0 0.019 14.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ78102.1 - 0.00093 18.9 0.1 0.0027 17.4 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ78102.1 - 0.0071 15.8 0.0 0.18 11.3 0.1 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Somatomedin_B PF01033.17 KNZ78104.1 - 0.23 11.9 1.4 0.38 11.2 1.4 1.3 1 0 0 1 1 1 0 Somatomedin B domain Ank_4 PF13637.6 KNZ78106.1 - 7.7e-09 35.9 0.0 0.0061 17.1 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ78106.1 - 1.3e-06 28.9 0.0 2.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KNZ78106.1 - 1.9e-05 24.9 0.3 0.0069 16.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KNZ78106.1 - 0.0034 17.7 0.1 0.58 10.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 KNZ78106.1 - 0.066 13.6 0.1 1.7 9.0 0.0 2.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) 4HBT_2 PF13279.6 KNZ78108.1 - 1.7e-06 28.5 0.0 3.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily BTB PF00651.31 KNZ78109.1 - 1.2e-07 32.0 0.1 3e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain DUF5101 PF17031.5 KNZ78109.1 - 0.025 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) Misat_Tub_SegII PF10644.9 KNZ78110.1 - 6.7e-34 116.7 0.0 2.5e-33 114.9 0.0 2.1 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 KNZ78110.1 - 1.5e-30 106.2 0.0 2.6e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Gti1_Pac2 PF09729.9 KNZ78111.1 - 1.5e-28 100.1 1.1 3.8e-24 85.8 0.5 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Pkinase_Tyr PF07714.17 KNZ78112.1 - 1.1e-49 169.0 0.0 1.6e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ78112.1 - 3.9e-36 124.8 0.0 2.5e-35 122.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KNZ78112.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KNZ78112.1 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ78112.1 - 0.034 14.1 0.3 0.034 14.1 0.3 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ78112.1 - 0.043 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NPV_P10 PF05531.12 KNZ78112.1 - 0.06 13.8 1.2 0.2 12.1 0.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Clathrin_bdg PF15045.6 KNZ78112.1 - 0.17 11.9 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking EnY2 PF10163.9 KNZ78113.1 - 0.17 12.3 0.7 0.31 11.4 0.7 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 zf-C2H2_10 PF16588.5 KNZ78114.1 - 0.25 11.1 1.8 0.39 10.5 1.8 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KNZ78114.1 - 5.8 7.2 6.6 0.54 10.4 1.9 1.7 2 0 0 2 2 2 0 Zinc knuckle RT_RNaseH PF17917.1 KNZ78115.1 - 1.2e-10 41.6 0.0 3.1e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78115.1 - 2.3e-08 34.0 0.0 6.4e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase POT1PC PF16686.5 KNZ78116.1 - 0.068 13.0 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein gag-asp_proteas PF13975.6 KNZ78117.1 - 6e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78117.1 - 0.01 16.5 0.0 0.019 15.6 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Asp_protease PF09668.10 KNZ78117.1 - 0.018 14.8 0.1 0.083 12.7 0.1 1.9 1 1 1 2 2 2 0 Aspartyl protease Asp_protease_2 PF13650.6 KNZ78118.1 - 0.0062 17.1 0.0 0.0077 16.9 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KNZ78118.1 - 0.075 12.8 0.1 0.091 12.5 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Las1 PF04031.13 KNZ78121.1 - 2.7e-44 151.0 0.8 2.7e-44 151.0 0.8 2.0 2 1 0 2 2 2 1 Las1-like DLH PF01738.18 KNZ78123.1 - 2.8e-12 46.6 0.0 3.6e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Lyase_catalyt PF09093.11 KNZ78123.1 - 0.2 10.8 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic Prenylcys_lyase PF07156.14 KNZ78124.1 - 6e-66 223.0 0.0 8.6e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 KNZ78124.1 - 4e-10 39.8 0.0 1.1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KNZ78124.1 - 2.7e-08 33.5 0.0 6.8e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KNZ78124.1 - 2.4e-06 27.4 0.4 0.064 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KNZ78124.1 - 0.0088 16.0 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KNZ78124.1 - 0.015 14.5 0.0 0.43 9.8 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ammonium_transp PF00909.21 KNZ78125.1 - 3.6e-110 368.4 21.6 4.6e-110 368.0 21.6 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family BPL_LplA_LipB PF03099.19 KNZ78126.1 - 5.1e-05 23.2 0.0 9.7e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NAD_binding_10 PF13460.6 KNZ78127.1 - 9.4e-05 22.4 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KNZ78127.1 - 0.0077 16.7 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KNZ78127.1 - 0.11 12.1 0.1 0.17 11.4 0.1 1.3 1 1 0 1 1 1 0 NmrA-like family ATP11 PF06644.11 KNZ78128.1 - 6.9e-79 265.5 0.3 7.9e-79 265.2 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein Peptidase_M2 PF01401.18 KNZ78128.1 - 0.025 13.2 0.1 0.033 12.8 0.1 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme DEAD PF00270.29 KNZ78129.1 - 7.9e-44 149.5 1.6 9.6e-44 149.2 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78129.1 - 9.2e-32 109.7 0.2 1.1e-30 106.3 0.2 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78129.1 - 0.00012 22.1 0.0 0.00024 21.2 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KNZ78129.1 - 0.0015 18.9 1.1 0.0076 16.6 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KNZ78129.1 - 0.0045 16.7 0.2 0.0083 15.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 KNZ78129.1 - 0.03 13.6 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 KNZ78129.1 - 0.035 12.9 1.2 2 7.1 0.0 2.6 4 0 0 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GGDEF PF00990.21 KNZ78130.1 - 0.012 15.4 1.0 0.015 15.1 1.0 1.1 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain SOAR PF16533.5 KNZ78130.1 - 0.013 15.5 4.0 0.013 15.5 4.0 2.2 1 1 1 2 2 2 0 STIM1 Orai1-activating region NAF PF03822.14 KNZ78130.1 - 0.029 14.5 0.3 0.066 13.4 0.3 1.7 1 0 0 1 1 1 0 NAF domain DUF883 PF05957.13 KNZ78130.1 - 0.03 14.9 3.7 0.03 14.9 3.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3619 PF12279.8 KNZ78130.1 - 0.095 13.0 4.9 2.6 8.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) DUF948 PF06103.11 KNZ78130.1 - 0.24 11.7 7.9 0.95 9.8 1.2 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIVA PF05103.13 KNZ78130.1 - 0.34 11.0 11.8 0.49 10.5 11.8 1.3 1 0 0 1 1 1 0 DivIVA protein ISG65-75 PF11727.8 KNZ78130.1 - 1.6 7.9 16.5 2.5 7.3 16.5 1.4 1 1 0 1 1 1 0 Invariant surface glycoprotein YtxH PF12732.7 KNZ78130.1 - 3.2 8.3 18.0 2.1e+03 -0.7 18.0 2.9 1 1 0 1 1 1 0 YtxH-like protein PGA2 PF07543.12 KNZ78130.1 - 5.7 6.9 12.7 7.5 6.5 12.7 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 RR_TM4-6 PF06459.12 KNZ78130.1 - 5.8 6.7 11.8 6.7 6.5 11.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 p450 PF00067.22 KNZ78131.1 - 5.2e-54 183.7 0.0 7e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KNZ78132.1 - 1.2e-62 212.2 0.0 1.6e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acatn PF13000.7 KNZ78133.1 - 4e-146 487.7 28.3 7.4e-68 229.4 14.5 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 TPD52 PF04201.15 KNZ78133.1 - 0.0012 18.5 0.1 0.0026 17.4 0.1 1.5 2 0 0 2 2 2 1 Tumour protein D52 family THEG4 PF15834.5 KNZ78133.1 - 0.025 14.6 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Testis highly expressed protein 4 GYF PF02213.16 KNZ78134.1 - 3.9e-16 58.5 2.5 8.7e-16 57.3 2.5 1.7 1 0 0 1 1 1 1 GYF domain GPS2_interact PF15784.5 KNZ78134.1 - 0.11 12.9 0.0 0.11 12.9 0.0 2.8 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain Glyco_hydro_16 PF00722.21 KNZ78136.1 - 1.2e-08 34.6 0.1 4.5e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Arm PF00514.23 KNZ78137.1 - 8.5e-70 228.9 27.4 4.2e-13 48.8 0.1 10.5 10 1 0 10 10 10 10 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KNZ78137.1 - 1.6e-21 76.4 8.8 0.00076 19.9 0.3 7.3 6 2 1 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 KNZ78137.1 - 5.6e-18 65.1 4.1 0.024 15.0 0.0 7.2 4 2 3 7 7 7 6 HEAT repeats HEAT PF02985.22 KNZ78137.1 - 2e-14 52.4 10.1 0.16 12.3 0.0 8.6 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KNZ78137.1 - 1.2e-09 38.0 8.8 2.4e-05 24.0 0.7 2.9 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 KNZ78137.1 - 2.6e-07 29.2 3.2 4.2e-07 28.5 3.2 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KNZ78137.1 - 1.4e-06 27.9 7.8 0.26 10.6 0.0 4.4 1 1 2 4 4 4 3 V-ATPase subunit H Cnd1 PF12717.7 KNZ78137.1 - 0.00014 22.0 7.3 0.016 15.3 0.2 4.4 1 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 KNZ78137.1 - 0.00016 21.7 2.6 27 4.9 0.1 5.0 3 2 4 7 7 7 0 V-ATPase subunit H DUF3361 PF11841.8 KNZ78137.1 - 0.00083 19.3 6.7 0.96 9.4 0.0 4.2 1 1 3 4 4 4 1 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 KNZ78137.1 - 0.0046 17.5 4.8 11 7.0 0.6 5.6 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 KNZ78137.1 - 0.42 10.7 4.4 0.92 9.6 0.3 3.4 3 1 2 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Abhydrolase_2 PF02230.16 KNZ78138.1 - 6.9e-18 65.3 0.0 7.5e-18 65.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 KNZ78138.1 - 0.21 11.2 0.0 0.24 11.0 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PolyA_pol PF01743.20 KNZ78139.1 - 2.4e-27 95.8 0.0 4.3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KNZ78139.1 - 2.4e-06 27.2 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DEAD PF00270.29 KNZ78140.1 - 2.7e-39 134.8 0.0 4.2e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78140.1 - 6.2e-24 84.5 0.0 2.5e-23 82.5 0.0 2.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78140.1 - 5.7e-07 29.7 0.0 9.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_43 PF04616.14 KNZ78141.1 - 1.3e-19 70.6 2.0 2e-19 70.0 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KNZ78141.1 - 0.0019 18.5 3.6 0.004 17.4 3.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) CBM_35 PF16990.5 KNZ78141.1 - 0.0054 17.0 2.1 0.012 15.9 2.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Mito_carr PF00153.27 KNZ78142.1 - 1.3e-27 95.6 0.7 6.9e-15 54.8 0.0 3.0 3 1 0 3 3 3 2 Mitochondrial carrier protein Herpes_Helicase PF02689.14 KNZ78143.1 - 2.2e-07 29.2 0.0 2.3e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ78143.1 - 0.051 13.4 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ78144.1 - 6.2e-17 61.8 0.0 7.5e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ78144.1 - 0.0038 17.3 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 KNZ78148.1 - 0.17 12.0 1.6 0.3 11.2 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ78148.1 - 0.52 10.1 2.2 0.91 9.3 2.2 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger gag-asp_proteas PF13975.6 KNZ78150.1 - 0.013 16.1 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78150.1 - 0.034 14.8 0.0 0.075 13.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease VIT PF08487.10 KNZ78151.1 - 2.4e-26 92.1 0.0 3.9e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KNZ78151.1 - 1.6e-20 73.6 0.0 3.1e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KNZ78151.1 - 1.3e-07 32.2 0.0 3.8e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KNZ78151.1 - 9.9e-07 29.2 0.0 3.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KNZ78151.1 - 0.00017 21.1 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.6 KNZ78151.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain DEAD PF00270.29 KNZ78152.1 - 6.2e-37 127.1 0.1 9.6e-37 126.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78152.1 - 3.3e-24 85.4 0.1 1.6e-22 80.0 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78152.1 - 9.8e-09 35.4 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HATPase_c PF02518.26 KNZ78153.1 - 6.1e-28 97.6 0.0 1.3e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KNZ78153.1 - 5.4e-15 55.5 0.0 8e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KNZ78153.1 - 1.6e-14 53.7 0.0 9.8e-14 51.2 0.0 2.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KNZ78153.1 - 3.9e-13 50.1 0.1 3.3e-12 47.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain GAF PF01590.26 KNZ78153.1 - 1.2e-06 29.1 0.0 5.1e-06 27.1 0.0 2.2 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KNZ78153.1 - 4.4e-06 26.3 0.0 8.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78153.1 - 2.4e-05 23.8 0.0 4.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.6 KNZ78153.1 - 0.00015 21.6 0.0 0.00099 18.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.6 KNZ78153.1 - 0.067 13.5 0.8 4.9 7.4 0.0 3.6 2 2 1 3 3 3 0 AAA domain Pkinase PF00069.25 KNZ78154.1 - 4.2e-74 249.2 0.0 6.3e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78154.1 - 5.5e-36 124.2 0.0 1.2e-35 123.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase H2TH PF06831.14 KNZ78154.1 - 3.6e-17 62.1 0.0 8.4e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Haspin_kinase PF12330.8 KNZ78154.1 - 0.0027 16.7 0.0 0.065 12.2 0.0 2.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KNZ78154.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF3754 PF12576.8 KNZ78154.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) APH PF01636.23 KNZ78154.1 - 0.027 14.4 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Mak16 PF04874.14 KNZ78154.1 - 0.053 14.1 0.2 0.096 13.3 0.2 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region Utp12 PF04003.12 KNZ78155.1 - 1.3e-26 93.0 0.0 2.4e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 KNZ78155.1 - 3.9e-07 30.7 0.3 0.031 15.2 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78155.1 - 0.0041 17.4 0.2 1.1 9.7 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ78155.1 - 0.17 11.9 0.2 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.16 KNZ78156.1 - 1.3e-48 165.8 35.6 3.9e-33 114.8 13.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KNZ78156.1 - 1.1e-06 27.7 21.3 0.0024 16.8 6.8 3.2 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KNZ78156.1 - 0.0022 16.9 9.1 0.0022 16.9 9.1 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KNZ78156.1 - 0.0065 14.8 9.6 0.0069 14.7 1.0 3.2 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KNZ78157.1 - 5.5e-41 140.7 36.5 1.1e-29 103.4 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KNZ78157.1 - 0.0001 20.7 0.1 0.0001 20.7 0.1 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 KNZ78157.1 - 0.00068 18.6 20.7 0.029 13.2 8.8 3.4 2 2 0 3 3 3 3 MFS_1 like family Sugar_tr PF00083.24 KNZ78157.1 - 1.2 7.9 22.4 0.015 14.2 9.5 3.1 2 2 0 2 2 2 0 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 KNZ78157.1 - 8.6 6.4 13.1 7.5 6.6 2.7 2.7 3 0 0 3 3 3 0 Glycine zipper CorA PF01544.18 KNZ78158.1 - 0.025 13.9 0.5 0.046 13.0 0.1 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GHMP_kinases_N PF00288.26 KNZ78160.1 - 8.9e-08 32.3 0.4 1.9e-07 31.2 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KNZ78160.1 - 0.013 15.8 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal AAA_6 PF12774.7 KNZ78161.1 - 8e-127 422.7 0.0 7.6e-126 419.5 0.0 2.7 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KNZ78161.1 - 8.1e-114 380.8 9.2 8.1e-114 380.8 9.2 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KNZ78161.1 - 1.9e-72 243.0 0.3 1.9e-72 243.0 0.3 3.8 4 1 1 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 KNZ78161.1 - 6.3e-68 228.9 0.0 2.6e-67 226.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 KNZ78161.1 - 2.2e-49 168.4 0.0 7.8e-49 166.5 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 KNZ78161.1 - 9.2e-43 145.9 0.0 2.4e-36 125.0 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 KNZ78161.1 - 5.9e-36 123.8 0.0 1.2e-35 122.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 KNZ78161.1 - 6.3e-31 106.9 0.0 9.2e-30 103.2 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 KNZ78161.1 - 1.7e-26 93.1 11.6 3e-26 92.3 11.6 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KNZ78161.1 - 1.4e-22 80.1 0.0 1.5e-07 31.5 0.0 5.9 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 KNZ78161.1 - 4.2e-18 65.7 0.0 2.3e-17 63.3 0.0 2.4 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KNZ78161.1 - 6.1e-14 52.5 0.5 0.006 16.9 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA PF00004.29 KNZ78161.1 - 2e-13 50.9 0.0 0.00092 19.6 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KNZ78161.1 - 1.2e-11 44.9 5.4 0.053 13.7 0.0 6.5 6 0 0 6 6 5 3 AAA domain AAA_16 PF13191.6 KNZ78161.1 - 4.4e-09 37.0 0.0 0.59 10.5 0.0 6.4 5 0 0 5 5 5 1 AAA ATPase domain AAA_18 PF13238.6 KNZ78161.1 - 1.7e-08 35.1 1.6 0.11 13.0 0.0 6.3 5 0 0 5 5 5 2 AAA domain T2SSE PF00437.20 KNZ78161.1 - 2.4e-06 26.8 0.1 0.014 14.5 0.0 3.9 4 0 0 4 4 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 KNZ78161.1 - 4.1e-06 26.3 0.3 0.63 9.4 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KNZ78161.1 - 1.4e-05 24.5 0.0 0.36 10.1 0.0 3.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 KNZ78161.1 - 4.7e-05 23.5 2.2 0.00031 20.9 0.0 3.4 3 0 0 3 3 2 1 AAA+ lid domain AAA_19 PF13245.6 KNZ78161.1 - 5.2e-05 23.6 0.3 0.3 11.4 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 KNZ78161.1 - 0.00021 21.0 0.1 0.72 9.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 KNZ78161.1 - 0.0004 20.2 0.5 0.75 9.5 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_14 PF13173.6 KNZ78161.1 - 0.00046 20.2 0.0 1.5 8.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain ERM PF00769.19 KNZ78161.1 - 0.001 19.0 16.9 0.017 15.0 0.4 2.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Rad17 PF03215.15 KNZ78161.1 - 0.0042 17.0 0.0 24 4.8 0.0 4.3 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_21 PF13304.6 KNZ78161.1 - 0.0042 16.9 0.0 2.1 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 KNZ78161.1 - 0.0045 17.5 2.3 12 6.4 0.0 4.4 4 0 0 4 4 3 0 ABC transporter AAA_24 PF13479.6 KNZ78161.1 - 0.0047 16.7 0.7 22 4.7 0.0 4.5 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 KNZ78161.1 - 0.0066 16.8 0.0 23 5.4 0.0 4.4 4 0 0 4 4 4 0 RNA helicase DUF418 PF04235.12 KNZ78161.1 - 0.01 15.8 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF418) AAA_25 PF13481.6 KNZ78161.1 - 0.015 14.9 0.1 0.62 9.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 KNZ78161.1 - 0.039 13.9 0.5 15 5.6 0.0 3.8 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 KNZ78161.1 - 0.057 13.2 0.0 7.6 6.3 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase RuvB_N PF05496.12 KNZ78161.1 - 0.066 13.0 0.1 2.8 7.7 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 KNZ78161.1 - 0.077 12.6 1.5 41 3.7 0.1 3.8 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KNZ78161.1 - 0.099 12.4 0.2 12 5.7 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 KNZ78161.1 - 0.1 12.6 0.0 33 4.4 0.0 3.9 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit dNK PF01712.19 KNZ78161.1 - 0.12 12.2 1.3 0.55 10.0 0.3 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 KNZ78161.1 - 0.13 12.1 4.0 39 4.1 0.1 5.1 6 0 0 6 6 3 0 NACHT domain LOH1CR12 PF10158.9 KNZ78161.1 - 0.54 10.3 18.6 0.16 12.0 0.5 4.2 4 0 0 4 4 2 0 Tumour suppressor protein DUF4988 PF16378.5 KNZ78161.1 - 1.2 8.8 3.5 0.72 9.5 0.6 2.2 2 0 0 2 2 1 0 Domain of unknown function UPF0242 PF06785.11 KNZ78161.1 - 1.6 8.8 18.8 1.7 8.7 1.0 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 KNZ78161.1 - 2.5 8.1 5.6 49 3.9 0.0 4.1 3 0 0 3 3 3 0 Helicase HerA, central domain LSM PF01423.22 KNZ78162.1 - 4.3e-14 51.9 0.2 6.1e-14 51.5 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KNZ78162.1 - 0.003 17.2 0.2 0.0071 16.0 0.1 1.7 1 1 1 2 2 2 1 Hfq protein zf-C3HC4_3 PF13920.6 KNZ78163.1 - 9.9e-10 38.1 7.7 1.2e-09 37.8 7.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ78163.1 - 9.4e-09 35.0 9.5 1.3e-08 34.6 9.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ78163.1 - 1.7e-08 34.7 12.5 2.2e-08 34.3 12.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ78163.1 - 4.3e-08 32.9 9.8 5.9e-08 32.4 9.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ78163.1 - 6.3e-08 32.4 8.4 8.6e-08 31.9 8.4 1.1 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KNZ78163.1 - 1.8e-06 27.9 6.8 2.2e-06 27.6 4.8 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KNZ78163.1 - 2.5e-06 27.4 9.5 3.8e-06 26.8 9.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KNZ78163.1 - 3.5e-05 24.0 10.0 6.4e-05 23.2 10.0 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KNZ78163.1 - 0.00049 20.2 11.1 0.00053 20.1 9.9 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 KNZ78163.1 - 0.0019 18.2 2.1 0.0025 17.8 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KNZ78163.1 - 0.022 14.6 5.8 0.033 14.1 5.8 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KNZ78163.1 - 0.028 14.5 6.3 0.044 13.9 6.3 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 KNZ78163.1 - 0.18 11.6 8.4 0.4 10.5 8.4 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.21 KNZ78163.1 - 2.1 8.7 11.6 8.1 6.7 11.9 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Romo1 PF10247.9 KNZ78164.1 - 6.1e-24 84.2 10.1 7.9e-24 83.8 10.1 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 CS PF04969.16 KNZ78165.1 - 0.0037 18.2 0.0 0.007 17.4 0.0 1.5 1 0 0 1 1 1 1 CS domain BC10 PF06726.12 KNZ78166.1 - 1.4e-09 38.1 10.5 2.9e-09 37.0 10.5 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 WD40 PF00400.32 KNZ78167.1 - 9.2e-26 89.6 4.3 2.2e-06 28.3 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 KNZ78167.1 - 1.3e-08 34.0 0.1 0.0014 17.4 0.0 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KNZ78167.1 - 0.00042 20.6 0.0 9.3 6.6 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DivIC PF04977.15 KNZ78167.1 - 2.2 8.1 4.8 1.6 8.5 2.8 1.8 1 1 1 2 2 2 0 Septum formation initiator SprT-like PF10263.9 KNZ78168.1 - 1.5e-30 105.4 1.0 2.4e-30 104.7 1.0 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 KNZ78168.1 - 0.012 16.0 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Effector protein Ribosomal_S14 PF00253.21 KNZ78169.1 - 7.9e-14 51.2 3.7 8.7e-14 51.0 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PUF PF00806.19 KNZ78170.1 - 2.2e-55 181.3 12.1 5.2e-08 32.1 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat 7tm_7 PF08395.12 KNZ78170.1 - 0.00084 18.7 3.4 0.0013 18.1 3.4 1.2 1 0 0 1 1 1 1 7tm Chemosensory receptor Atg14 PF10186.9 KNZ78171.1 - 2.2e-12 46.7 0.1 4.5e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tox-ODYAM1 PF15642.6 KNZ78171.1 - 0.78 8.6 3.2 1.2 8.1 3.2 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Cullin PF00888.22 KNZ78173.1 - 2e-06 26.8 0.0 2.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family PARP PF00644.20 KNZ78174.1 - 7.5e-58 195.4 2.9 4.5e-57 192.8 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain WGR PF05406.15 KNZ78174.1 - 6.5e-20 71.0 0.7 1.6e-19 69.8 0.7 1.7 1 0 0 1 1 1 1 WGR domain PARP_reg PF02877.14 KNZ78174.1 - 1.1e-17 64.4 0.4 3e-14 53.3 0.1 2.3 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase, regulatory domain RNA_pol_Rpc4 PF05132.14 KNZ78174.1 - 0.28 11.6 10.9 0.029 14.8 5.9 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 TAF4 PF05236.14 KNZ78174.1 - 0.65 9.7 5.2 4.4 7.0 5.7 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family PBP1_TM PF14812.6 KNZ78174.1 - 1.6 9.2 11.2 2.7 8.4 4.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG_box PF00505.19 KNZ78175.1 - 1.8e-12 47.5 0.5 3.2e-12 46.7 0.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ78175.1 - 0.0027 18.3 0.2 0.0027 18.3 0.2 2.0 2 0 0 2 2 2 1 HMG-box domain DHO_dh PF01180.21 KNZ78176.1 - 2.3e-12 46.7 0.3 4.9e-11 42.4 0.3 2.2 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.16 KNZ78177.1 - 2e-40 137.9 0.0 2.5e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MFAP1 PF06991.11 KNZ78179.1 - 2.1e-67 227.2 32.3 2.1e-67 227.2 32.3 2.8 3 0 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 KNZ78179.1 - 0.091 12.9 1.6 0.19 11.8 1.6 1.6 1 1 0 1 1 1 0 Zinc knuckle NAD_binding_8 PF13450.6 KNZ78180.1 - 1.7e-12 47.4 0.0 3.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ78180.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ78180.1 - 0.18 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain UMP1 PF05348.11 KNZ78181.1 - 1e-28 99.9 0.2 1.4e-28 99.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 SPRY PF00622.28 KNZ78182.1 - 7.4e-21 74.5 0.1 1.2e-20 73.9 0.1 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KNZ78182.1 - 7.8e-20 71.3 0.0 2.1e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KNZ78182.1 - 0.00042 20.2 1.4 0.00051 19.9 0.1 1.9 2 0 0 2 2 2 1 LisH Ricin_B_lectin PF00652.22 KNZ78183.1 - 0.00011 22.4 0.0 3.7 7.8 0.0 3.7 4 0 0 4 4 4 2 Ricin-type beta-trefoil lectin domain LexA_DNA_bind PF01726.16 KNZ78183.1 - 0.18 11.6 0.1 0.45 10.3 0.1 1.6 1 0 0 1 1 1 0 LexA DNA binding domain Porphobil_deam PF01379.20 KNZ78184.1 - 1.5e-71 240.2 0.0 2e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KNZ78184.1 - 1.3e-15 57.5 0.5 2.6e-15 56.5 0.5 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UQ_con PF00179.26 KNZ78185.1 - 1.2e-23 83.3 0.0 1.7e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 KNZ78185.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Copper-fist PF00649.18 KNZ78186.1 - 1e-14 53.7 1.9 1e-14 53.7 1.9 3.6 4 1 0 4 4 4 1 Copper fist DNA binding domain Nfu_N PF08712.11 KNZ78187.1 - 3.7e-31 107.0 0.0 1.1e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KNZ78187.1 - 1.4e-26 92.5 0.2 2.3e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KNZ78187.1 - 0.0063 16.6 0.3 0.012 15.7 0.3 1.4 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus DUF4745 PF15923.5 KNZ78187.1 - 0.069 13.1 0.1 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Glyco_trans_1_4 PF13692.6 KNZ78188.1 - 6.1e-08 33.2 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KNZ78188.1 - 0.00011 22.7 0.0 0.00028 21.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KNZ78188.1 - 0.00014 21.4 0.0 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KNZ78188.1 - 0.0041 17.1 0.5 0.0078 16.2 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 KNZ78188.1 - 0.0051 17.2 0.0 0.0098 16.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 SBDS_C PF09377.10 KNZ78189.1 - 4.1e-37 126.7 0.8 6.8e-37 126.0 0.8 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 KNZ78189.1 - 8e-24 83.5 1.7 1.4e-23 82.7 0.4 1.9 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myc_N PF01056.18 KNZ78189.1 - 0.0022 17.9 1.2 0.003 17.5 1.2 1.1 1 0 0 1 1 1 1 Myc amino-terminal region Alba PF01918.21 KNZ78189.1 - 0.094 12.6 0.6 6.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Alba BAR PF03114.18 KNZ78190.1 - 4.8e-36 124.6 0.2 7.6e-36 123.9 0.2 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KNZ78190.1 - 1.6e-15 56.4 0.0 2.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ78190.1 - 9.4e-14 51.0 0.1 1.5e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ78190.1 - 3.7e-09 36.1 0.0 6.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Prophage_tail PF06605.11 KNZ78190.1 - 0.0076 15.5 0.3 0.056 12.7 0.2 2.0 2 0 0 2 2 2 1 Prophage endopeptidase tail SAP30_Sin3_bdg PF13867.6 KNZ78192.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 RhlB PF12300.8 KNZ78192.1 - 1.5 8.9 12.1 0.31 11.2 4.5 2.4 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Chorismate_synt PF01264.21 KNZ78193.1 - 9.6e-137 455.1 0.0 1.1e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase UPF0052 PF01933.18 KNZ78194.1 - 2.4e-40 138.6 0.0 2.6e-31 108.9 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0052 DUF4687 PF15747.5 KNZ78194.1 - 0.039 14.4 0.1 0.077 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4687) ABC_tran PF00005.27 KNZ78197.1 - 1.4e-47 161.6 0.0 3.5e-24 85.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KNZ78197.1 - 5.7e-22 77.6 4.6 5.7e-22 77.6 4.6 2.6 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 KNZ78197.1 - 1.8e-15 57.6 14.5 0.00097 19.0 0.0 4.8 4 2 0 6 6 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNZ78197.1 - 3.1e-08 33.3 0.4 0.0057 16.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KNZ78197.1 - 6.1e-07 29.5 0.5 0.024 14.7 0.3 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ78197.1 - 1e-06 28.8 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNZ78197.1 - 1.2e-06 28.1 0.1 0.055 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 KNZ78197.1 - 0.00012 22.4 0.0 0.39 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KNZ78197.1 - 0.00017 21.6 0.0 0.2 11.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 KNZ78197.1 - 0.00031 19.8 2.6 0.084 11.8 0.0 2.9 4 0 0 4 4 4 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KNZ78197.1 - 0.00064 20.3 1.8 4.6 7.8 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KNZ78197.1 - 0.00085 19.5 0.7 0.46 10.6 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_30 PF13604.6 KNZ78197.1 - 0.0014 18.4 0.1 0.35 10.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KNZ78197.1 - 0.0021 18.3 1.4 1.4 9.2 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_24 PF13479.6 KNZ78197.1 - 0.006 16.3 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KNZ78197.1 - 0.011 16.2 0.0 5.5 7.4 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KNZ78197.1 - 0.013 15.9 0.0 7.9 6.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 KNZ78197.1 - 0.013 15.9 3.6 1.5 9.2 0.8 3.3 3 1 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 KNZ78197.1 - 0.013 15.7 0.0 5.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 KNZ78197.1 - 0.014 15.0 0.0 5.3 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 KNZ78197.1 - 0.017 14.3 0.0 0.51 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.6 KNZ78197.1 - 0.018 14.7 9.9 0.5 10.0 0.4 3.7 4 0 0 4 4 4 0 AAA ATPase domain Dynamin_N PF00350.23 KNZ78197.1 - 0.025 14.6 0.7 1.3 9.1 0.0 3.1 3 1 0 3 3 2 0 Dynamin family NTPase_1 PF03266.15 KNZ78197.1 - 0.036 14.0 0.1 10 6.0 0.1 2.6 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 KNZ78197.1 - 0.039 13.1 0.1 5 6.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 KNZ78197.1 - 0.058 13.0 0.2 27 4.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.14 KNZ78197.1 - 0.066 13.2 0.3 6.2 6.8 0.1 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF1367 PF07105.11 KNZ78197.1 - 0.068 12.8 0.2 1.8 8.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1367) AAA_23 PF13476.6 KNZ78197.1 - 0.076 13.5 0.0 0.37 11.2 0.0 4.4 5 0 0 5 5 4 0 AAA domain DUF87 PF01935.17 KNZ78197.1 - 1 9.4 7.8 0.89 9.6 0.1 3.4 4 0 0 4 4 3 0 Helicase HerA, central domain DNA_topoisoIV PF00521.20 KNZ78198.1 - 1.6e-106 356.8 3.0 1.7e-104 350.1 3.0 2.3 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KNZ78198.1 - 2e-51 173.6 0.6 5.5e-51 172.2 0.6 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KNZ78198.1 - 1.8e-25 89.4 2.9 4.1e-25 88.2 2.9 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KNZ78198.1 - 1.4e-10 41.6 0.0 4.1e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KNZ78198.1 - 2.3e-07 30.9 0.1 2.8e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 Toprim domain MMR_HSR1_C PF08438.10 KNZ78198.1 - 0.052 14.1 4.7 8.2 7.0 0.1 3.9 3 0 0 3 3 3 0 GTPase of unknown function C-terminal HEXIM PF15313.6 KNZ78198.1 - 3.2 8.0 6.2 4.9 7.3 2.6 3.0 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Metal_CEHH PF14455.6 KNZ78199.1 - 0.14 11.8 0.7 0.18 11.4 0.7 1.3 1 1 0 1 1 1 0 Predicted metal binding domain TFIIA PF03153.13 KNZ78199.1 - 2.7 7.9 10.7 3 7.7 10.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP68 PF16969.5 KNZ78200.1 - 6.2e-82 276.4 3.4 6.2e-82 276.4 3.4 1.9 2 0 0 2 2 2 1 RNA-binding signal recognition particle 68 ANAPC3 PF12895.7 KNZ78200.1 - 0.32 11.2 4.7 6.7 7.0 0.1 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 ArsA_ATPase PF02374.15 KNZ78201.1 - 3.4e-112 374.6 0.8 3.9e-112 374.4 0.8 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KNZ78201.1 - 1.5e-14 54.3 0.1 5.7e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 KNZ78201.1 - 1.5e-12 47.7 0.0 3.2e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 KNZ78201.1 - 4.1e-06 26.4 0.1 1.2e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 KNZ78201.1 - 2.2e-05 24.1 0.0 8e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 KNZ78201.1 - 2.8e-05 23.7 4.4 0.00015 21.3 1.4 2.6 2 2 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 KNZ78201.1 - 6.2e-05 22.7 0.6 0.001 18.8 0.2 2.3 1 1 1 2 2 2 1 SRP54-type protein, GTPase domain VirC1 PF07015.11 KNZ78201.1 - 0.019 14.3 0.3 0.047 13.0 0.1 1.8 2 1 0 2 2 2 0 VirC1 protein AAA_25 PF13481.6 KNZ78201.1 - 0.021 14.4 1.0 0.19 11.3 1.0 2.3 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 KNZ78201.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 KNZ78201.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ78201.1 - 0.15 12.4 0.7 2.5 8.5 0.3 2.8 2 2 1 3 3 3 0 RNA helicase Fe-S_biosyn PF01521.20 KNZ78203.1 - 1.1e-20 73.9 0.0 1.4e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Y_phosphatase PF00102.27 KNZ78204.1 - 6e-56 189.6 0.1 7.3e-31 107.5 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.20 KNZ78204.1 - 6.6e-06 26.6 0.0 2.2e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KNZ78204.1 - 0.0042 17.1 0.0 0.0075 16.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KNZ78204.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.22 KNZ78205.1 - 4.4e-13 48.9 0.0 3.8e-07 29.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ku PF02735.16 KNZ78206.1 - 4.9e-26 91.7 0.1 9e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 KNZ78206.1 - 2.2e-23 82.7 0.3 7.6e-23 80.9 0.0 2.0 2 0 0 2 2 2 1 Ku C terminal domain like VWA PF00092.28 KNZ78206.1 - 3e-06 27.6 0.1 9.1e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KNZ78206.1 - 2.6e-05 24.8 0.0 0.00032 21.3 0.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain SNF2_N PF00176.23 KNZ78207.1 - 1.8e-70 237.4 0.3 5.4e-70 235.8 0.4 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 KNZ78207.1 - 2.7e-20 72.2 0.1 7.2e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 KNZ78207.1 - 1.2e-18 67.5 1.5 1.3e-17 64.1 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 KNZ78207.1 - 6.5e-18 64.8 8.6 3.7e-17 62.4 8.6 2.5 1 0 0 1 1 1 1 HSA QLQ PF08880.11 KNZ78207.1 - 2.2e-14 52.9 0.1 9e-14 50.9 0.1 2.2 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 KNZ78207.1 - 5.2e-14 52.6 0.5 5.2e-14 52.6 0.5 3.7 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 KNZ78207.1 - 6.7e-07 29.5 0.0 2.3e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KNZ78207.1 - 2.4e-05 23.6 1.7 0.00011 21.5 0.0 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 TPR_1 PF00515.28 KNZ78208.1 - 1.4e-45 151.3 25.9 2.5e-07 30.2 0.0 9.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ78208.1 - 4.2e-45 148.3 18.7 1.3e-05 24.9 0.2 9.6 9 1 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ78208.1 - 2.9e-35 117.5 7.5 4.8e-05 23.2 0.0 9.7 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ78208.1 - 1.4e-27 96.1 5.0 2.1e-06 28.2 0.0 6.0 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ78208.1 - 2.1e-25 88.1 22.3 3.4e-06 26.7 0.4 9.0 6 3 4 10 10 10 6 TPR repeat TPR_17 PF13431.6 KNZ78208.1 - 3e-23 80.5 5.7 0.0021 18.3 0.1 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ78208.1 - 4.2e-23 80.0 10.9 0.0014 19.3 0.0 8.9 3 2 6 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ78208.1 - 3.1e-21 73.8 12.3 0.25 11.5 0.2 9.3 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ78208.1 - 6.6e-21 74.4 15.0 7.1e-05 23.0 0.0 7.0 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ78208.1 - 4.2e-20 72.0 16.7 0.00016 22.1 0.3 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ78208.1 - 2.8e-17 62.1 12.3 0.021 15.4 0.0 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ78208.1 - 7.9e-14 51.6 7.7 0.034 14.3 0.0 6.2 3 1 4 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ78208.1 - 1.1e-10 41.6 6.8 7.2e-06 26.1 0.6 3.5 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KNZ78208.1 - 4.3e-05 23.1 8.2 1.9 7.8 0.0 4.5 2 2 3 5 5 5 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 KNZ78208.1 - 0.00013 21.3 6.8 0.37 9.9 1.7 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KNZ78208.1 - 0.002 18.4 0.1 0.0094 16.3 0.1 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat RPN7 PF10602.9 KNZ78208.1 - 0.0023 17.7 0.8 17 5.1 0.0 4.6 4 1 1 5 5 5 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 KNZ78208.1 - 0.017 14.9 11.6 0.62 9.7 0.4 4.3 1 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 KNZ78208.1 - 0.02 14.3 1.4 0.31 10.4 0.1 2.4 2 1 1 3 3 3 0 MalT-like TPR region DUF2989 PF11207.8 KNZ78208.1 - 0.1 12.3 0.5 2.3 7.9 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2989) ChAPs PF09295.10 KNZ78208.1 - 0.12 11.3 0.1 11 4.9 0.1 2.4 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 KNZ78208.1 - 1.1 9.7 3.5 8.2 6.9 0.2 3.2 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 KNZ78208.1 - 6 6.9 17.5 36 4.4 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Erf4 PF10256.9 KNZ78209.1 - 5.5e-28 97.4 0.2 1.5e-27 96.0 0.1 1.7 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family bZIP_1 PF00170.21 KNZ78210.1 - 1.7e-11 44.1 14.3 2.9e-11 43.3 14.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 KNZ78210.1 - 2.8e-05 24.0 0.1 2.8e-05 24.0 0.1 3.7 3 1 0 3 3 2 1 Transcription factor PAP1 bZIP_2 PF07716.15 KNZ78210.1 - 0.00024 21.1 14.2 0.00024 21.1 14.2 2.1 1 1 1 2 2 2 1 Basic region leucine zipper SHE3 PF17078.5 KNZ78210.1 - 0.0038 17.0 6.5 0.0065 16.2 6.5 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 CCDC85 PF10226.9 KNZ78210.1 - 0.02 14.6 0.6 0.02 14.6 0.6 2.1 2 0 0 2 2 2 0 CCDC85 family TMCO5 PF14992.6 KNZ78210.1 - 0.065 12.8 4.6 0.11 12.1 4.6 1.3 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.15 KNZ78210.1 - 0.071 12.9 3.5 0.17 11.7 3.5 1.6 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KNZ78210.1 - 0.21 12.3 1.1 0.43 11.3 1.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA ATG16 PF08614.11 KNZ78210.1 - 0.37 11.0 16.6 0.092 13.0 10.0 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF5094 PF17015.5 KNZ78210.1 - 1.5 8.9 6.5 3 7.9 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) XhlA PF10779.9 KNZ78210.1 - 1.7 8.9 3.7 3.7 7.8 3.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA GIT_CC PF16559.5 KNZ78210.1 - 2.9 7.8 5.7 1.4 8.9 2.4 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor GvpL_GvpF PF06386.11 KNZ78210.1 - 3.2 7.6 6.9 5.6 6.8 6.9 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Brr6_like_C_C PF10104.9 KNZ78211.1 - 2.1e-41 140.8 0.6 3.1e-41 140.2 0.6 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain CLP_protease PF00574.23 KNZ78212.1 - 4.4e-69 232.0 0.0 6.3e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Clp protease Reprolysin_5 PF13688.6 KNZ78213.1 - 1.7e-43 149.0 4.7 3.3e-43 148.1 4.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KNZ78213.1 - 1.6e-41 142.2 0.9 2.4e-41 141.6 0.9 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KNZ78213.1 - 1.9e-41 142.1 2.5 3.1e-41 141.4 2.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 KNZ78213.1 - 7.1e-13 49.2 0.0 3.3e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 KNZ78213.1 - 1.7e-06 28.1 5.0 7.1e-06 26.1 5.0 2.1 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 KNZ78213.1 - 0.00061 20.0 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 KNZ78213.1 - 0.016 15.7 2.7 0.016 15.7 2.7 2.2 2 0 0 2 2 2 0 ADAM cysteine-rich domain DUF3716 PF12511.8 KNZ78214.1 - 0.57 10.3 3.7 0.25 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) SHS2_Rpb7-N PF03876.17 KNZ78217.1 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KNZ78217.1 - 9.2e-12 45.1 0.1 1.8e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KNZ78217.1 - 0.013 15.8 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DEAD PF00270.29 KNZ78219.1 - 3e-46 157.4 0.0 6.4e-46 156.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78219.1 - 9.3e-34 116.1 0.0 2.8e-29 101.7 0.0 3.4 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78219.1 - 0.00074 19.6 3.0 0.0013 18.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KNZ78219.1 - 0.046 13.1 0.0 0.046 13.1 0.0 3.7 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 KNZ78219.1 - 0.27 10.4 0.0 0.27 10.4 0.0 2.3 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase DUF4551 PF15087.6 KNZ78219.1 - 2.9 6.6 13.2 4.7 5.9 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Oxysterol_BP PF01237.18 KNZ78220.1 - 1.1e-82 277.9 0.0 6.2e-74 249.1 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein ADIP PF11559.8 KNZ78221.1 - 0.00073 19.6 10.6 0.00073 19.6 10.6 6.4 3 1 4 7 7 7 2 Afadin- and alpha -actinin-Binding PAM2 PF07145.15 KNZ78221.1 - 1.2 9.0 7.3 18 5.3 0.6 3.5 3 0 0 3 3 3 0 Ataxin-2 C-terminal region PBP PF01161.20 KNZ78222.1 - 8.3e-14 52.0 0.5 1.4e-13 51.3 0.5 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FYVE PF01363.21 KNZ78223.1 - 7.8e-19 67.6 3.0 1.4e-18 66.8 3.0 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 KNZ78223.1 - 0.027 14.7 2.7 0.027 14.7 2.7 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF1908 PF08926.11 KNZ78223.1 - 0.24 10.5 5.8 0.37 9.8 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) zf-AN1 PF01428.16 KNZ78223.1 - 2.8 8.2 9.1 12 6.1 9.1 2.1 1 1 0 1 1 1 0 AN1-like Zinc finger DNA_methylase PF00145.17 KNZ78224.1 - 1.2e-31 110.3 0.0 1.6e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RNase_H PF00075.24 KNZ78227.1 - 1.5e-05 25.2 0.0 1.6e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 RNase H RPN6_N PF18055.1 KNZ78228.1 - 9.1e-44 148.6 2.1 2.8e-43 147.0 0.9 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 KNZ78228.1 - 5.3e-16 59.0 0.1 1.2e-15 57.8 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_MalT PF17874.1 KNZ78228.1 - 0.0054 16.1 1.1 0.0054 16.1 1.1 2.7 3 0 0 3 3 3 1 MalT-like TPR region ANAPC5 PF12862.7 KNZ78228.1 - 0.0084 16.1 0.7 0.033 14.2 0.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 KNZ78228.1 - 0.08 13.0 9.8 25 5.2 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DDRGK PF09756.9 KNZ78228.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 DDRGK domain TPR_14 PF13428.6 KNZ78228.1 - 0.61 11.1 12.7 51 5.1 0.2 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ78228.1 - 0.82 10.0 16.0 0.18 12.1 1.4 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ78228.1 - 7.6 7.1 16.6 0.35 11.4 0.8 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 KNZ78229.1 - 7.8e-53 178.7 0.0 1.2e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KNZ78229.1 - 3.5e-17 62.8 0.3 3.7e-16 59.5 0.1 2.5 2 1 1 3 3 3 1 PCI domain TPR_15 PF13429.6 KNZ78229.1 - 0.053 12.7 0.1 0.089 12.0 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ78229.1 - 0.067 13.3 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PIF1 PF05970.14 KNZ78232.1 - 9.5e-05 21.7 0.1 9.5e-05 21.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KNZ78233.1 - 1.7e-28 99.9 0.1 2e-28 99.6 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ78233.1 - 0.0072 16.3 0.0 0.0093 16.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ78233.1 - 0.025 14.3 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ78233.1 - 0.075 13.4 0.0 0.092 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Torsin PF06309.11 KNZ78233.1 - 0.19 11.9 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Torsin Kdo PF06293.14 KNZ78234.1 - 2.7e-06 26.9 0.1 4.9e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNZ78234.1 - 2.4e-05 23.8 0.2 5.1e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ78234.1 - 0.0021 18.0 0.5 0.0042 17.0 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ78234.1 - 0.018 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 KNZ78234.1 - 0.081 12.5 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KNZ78234.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ANAPC4_WD40 PF12894.7 KNZ78237.1 - 0.018 15.4 0.3 22 5.4 0.0 3.8 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ78237.1 - 0.028 15.3 0.3 14 6.8 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_2 PF13360.6 KNZ78237.1 - 0.084 12.4 0.0 0.51 9.9 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain zf-RVT PF13966.6 KNZ78239.1 - 0.011 16.4 0.2 0.033 14.9 0.2 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Aldo_ket_red PF00248.21 KNZ78248.1 - 4.1e-42 144.4 0.0 3.2e-41 141.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family E3_binding PF02817.17 KNZ78248.1 - 0.056 13.8 0.0 0.64 10.4 0.1 2.3 2 0 0 2 2 2 0 e3 binding domain Proteasome PF00227.26 KNZ78249.1 - 1.1e-32 113.0 0.0 1.5e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Rot1 PF10681.9 KNZ78250.1 - 5.8e-58 195.9 0.1 7.1e-58 195.6 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal MutS_I PF01624.20 KNZ78251.1 - 3.5e-08 33.7 0.0 3.9e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 MutS domain I YgbA_NO PF11756.8 KNZ78251.1 - 0.014 15.7 0.2 0.017 15.5 0.2 1.1 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter V4R PF02830.18 KNZ78251.1 - 0.091 12.8 0.1 0.17 11.9 0.1 1.4 1 1 0 1 1 1 0 V4R domain DUF4743 PF15916.5 KNZ78251.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) HisG PF01634.18 KNZ78253.1 - 2.2e-52 177.2 0.0 2.9e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KNZ78253.1 - 8.1e-25 86.8 0.0 2.1e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 KNZ78253.1 - 3.9e-06 27.0 0.1 5.8e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Pro-kuma_activ PF09286.11 KNZ78254.1 - 1.5e-45 155.0 0.0 2.6e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KNZ78254.1 - 0.0031 16.8 0.7 0.005 16.1 0.7 1.2 1 0 0 1 1 1 1 Subtilase family Utp12 PF04003.12 KNZ78255.1 - 0.036 14.4 2.8 6.8 7.1 0.1 3.1 3 1 0 3 3 3 0 Dip2/Utp12 Family DUF5413 PF17434.2 KNZ78255.1 - 0.16 12.3 0.1 0.53 10.6 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5413) Glycos_transf_3 PF00591.21 KNZ78256.1 - 4.1e-79 265.7 0.0 5.4e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KNZ78256.1 - 4.9e-09 35.9 0.0 1.2e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Pro-kuma_activ PF09286.11 KNZ78258.1 - 5.4e-41 140.2 0.0 8.6e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KNZ78258.1 - 0.023 13.9 1.0 0.035 13.4 1.0 1.2 1 0 0 1 1 1 0 Subtilase family Sad1_UNC PF07738.13 KNZ78259.1 - 1.3e-22 80.2 0.0 2.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CK2S PF15011.6 KNZ78259.1 - 0.0026 17.6 0.3 0.0062 16.4 0.3 1.6 1 0 0 1 1 1 1 Casein Kinase 2 substrate NACHT PF05729.12 KNZ78260.1 - 0.014 15.3 0.1 0.029 14.3 0.1 1.5 1 1 0 1 1 1 0 NACHT domain C1_1 PF00130.22 KNZ78262.1 - 0.64 9.9 7.7 2.8 7.9 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NOT2_3_5 PF04153.18 KNZ78265.1 - 3.9e-32 111.1 0.6 4.7e-32 110.8 0.6 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Prenyltrans PF00432.21 KNZ78266.1 - 4.8e-27 93.4 12.0 2.4e-11 43.2 2.1 4.9 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Chromo PF00385.24 KNZ78267.1 - 0.00012 21.9 0.1 0.00016 21.5 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 KNZ78268.1 - 8.5e-10 38.4 0.0 2.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78268.1 - 0.00069 19.0 0.0 0.042 13.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KNZ78268.1 - 0.16 11.0 0.1 0.23 10.4 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Prenyltrans PF00432.21 KNZ78270.1 - 0.22 11.3 2.6 1e+02 2.7 0.1 4.0 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat Myosin_head PF00063.21 KNZ78271.1 - 4.8e-32 111.0 8.2 3e-20 72.1 1.0 3.1 1 1 2 3 3 3 3 Myosin head (motor domain) O-FucT PF10250.9 KNZ78271.1 - 1.6e-09 38.0 0.0 7e-09 35.8 0.0 2.0 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Metallophos PF00149.28 KNZ78275.1 - 4.4e-15 56.7 2.9 5.9e-15 56.3 2.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ78275.1 - 1.4e-10 41.6 0.1 1e-09 38.8 0.1 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pkinase_Tyr PF07714.17 KNZ78276.1 - 2.2e-42 145.1 0.0 3.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ78276.1 - 2.5e-39 135.2 0.0 3.9e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KNZ78276.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ78276.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ78276.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ENTH PF01417.20 KNZ78278.1 - 1e-37 128.9 0.1 1.7e-37 128.3 0.1 1.3 1 0 0 1 1 1 1 ENTH domain DUF1031 PF06275.11 KNZ78278.1 - 0.14 12.4 0.1 4.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) Laminin_I PF06008.14 KNZ78278.1 - 0.52 10.0 2.0 0.38 10.4 0.2 1.6 2 0 0 2 2 2 0 Laminin Domain I GRP PF07172.11 KNZ78278.1 - 2.7 8.7 15.5 5.8 7.7 15.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family cobW PF02492.19 KNZ78279.1 - 8.4e-48 162.3 0.0 1.2e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KNZ78279.1 - 9.7e-06 25.4 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 KNZ78279.1 - 4.9e-05 23.0 0.0 0.089 12.3 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNZ78279.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ78279.1 - 0.0006 19.8 0.0 0.15 11.9 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KNZ78279.1 - 0.0024 18.0 0.1 0.0061 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KNZ78279.1 - 0.0051 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ78279.1 - 0.032 14.0 0.1 0.085 12.6 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 KNZ78279.1 - 0.038 13.0 0.4 0.17 10.9 0.0 2.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KNZ78279.1 - 0.039 14.5 0.0 0.089 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KNZ78279.1 - 0.046 13.6 0.3 0.52 10.2 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MobB PF03205.14 KNZ78279.1 - 0.06 13.3 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KNZ78279.1 - 0.061 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 KNZ78279.1 - 0.081 12.4 0.1 12 5.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_29 PF13555.6 KNZ78279.1 - 0.18 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DSPc PF00782.20 KNZ78280.1 - 2.6e-28 98.5 0.0 3.3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KNZ78280.1 - 0.00068 19.9 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain UAA PF08449.11 KNZ78281.1 - 4e-44 151.0 8.4 5.7e-44 150.5 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 KNZ78281.1 - 6.7e-10 39.3 17.6 4.6e-07 30.1 12.3 3.0 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 KNZ78281.1 - 0.00023 20.3 6.2 0.1 11.5 0.9 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 KNZ78281.1 - 0.001 18.3 5.9 0.1 11.8 0.9 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter TPT PF03151.16 KNZ78281.1 - 0.017 14.5 5.8 0.28 10.5 0.6 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF5336 PF17270.2 KNZ78281.1 - 2.2 7.9 7.3 10 5.7 0.0 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5336) Pkinase PF00069.25 KNZ78282.1 - 1.7e-09 37.4 0.0 1.6e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78282.1 - 0.0059 15.9 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SIS PF01380.22 KNZ78283.1 - 3.9e-61 204.7 0.2 1.9e-34 118.3 0.0 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KNZ78283.1 - 3.8e-15 56.3 0.0 8.9e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KNZ78283.1 - 1.1e-11 44.7 0.0 2.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KNZ78283.1 - 0.00051 19.0 0.0 0.00086 18.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 KNZ78283.1 - 0.093 12.8 0.0 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 SIS domain p450 PF00067.22 KNZ78285.1 - 1e-58 199.2 0.0 1.4e-58 198.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4791 PF16039.5 KNZ78285.1 - 0.053 13.1 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) OCRE PF17780.1 KNZ78286.1 - 0.46 10.5 7.4 1.6 8.8 3.7 2.4 1 1 1 2 2 2 0 OCRE domain gag-asp_proteas PF13975.6 KNZ78287.1 - 0.00031 21.3 0.0 0.00064 20.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78287.1 - 0.0037 17.9 0.0 0.0067 17.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease XH PF03469.14 KNZ78288.1 - 0.0084 16.0 0.4 0.2 11.6 0.0 2.1 2 0 0 2 2 2 2 XH domain gag-asp_proteas PF13975.6 KNZ78290.1 - 1.8e-05 25.2 0.0 4.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78290.1 - 0.00032 21.3 0.0 0.00084 19.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF667 PF05018.13 KNZ78293.1 - 3.7e-17 62.6 0.0 4.8e-09 36.2 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) Peripla_BP_2 PF01497.18 KNZ78294.1 - 0.09 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Con-6 PF10346.9 KNZ78297.1 - 3.3e-30 103.8 2.3 8.3e-15 54.5 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 KNZ78297.1 - 0.00098 19.0 1.0 0.038 13.8 0.2 2.2 1 1 0 2 2 2 2 SpoIIIAH-like protein ORC_WH_C PF18137.1 KNZ78298.1 - 9.7e-44 148.8 0.2 1.3e-43 148.4 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal MutS_V PF00488.21 KNZ78299.1 - 6.8e-64 215.4 0.1 1.5e-63 214.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KNZ78299.1 - 2.1e-37 129.2 1.2 2.1e-37 129.2 1.2 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 KNZ78299.1 - 4.8e-27 94.4 0.3 6.1e-23 81.2 0.1 2.5 2 0 0 2 2 2 2 MutS domain I MutS_II PF05188.17 KNZ78299.1 - 1.7e-11 44.5 0.0 5.6e-11 42.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KNZ78299.1 - 0.00062 20.1 0.4 0.0016 18.7 0.4 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 KNZ78299.1 - 0.043 13.6 0.2 0.14 11.9 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 KNZ78299.1 - 0.14 12.6 0.2 0.14 12.6 0.2 2.6 2 0 0 2 2 2 0 ABC transporter Methyltransf_16 PF10294.9 KNZ78300.1 - 2.5e-11 43.6 0.0 5.3e-11 42.6 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KNZ78300.1 - 0.098 13.4 0.0 0.22 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Rad51 PF08423.11 KNZ78301.1 - 2.4e-07 30.3 0.3 4.8e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 Rad51 RecA PF00154.21 KNZ78301.1 - 0.00019 21.0 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KNZ78301.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.15 KNZ78301.1 - 0.0063 15.9 0.3 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 KNZ78301.1 - 0.016 15.0 0.0 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein DIMCO_N PF16844.5 KNZ78301.1 - 0.029 14.7 0.2 0.34 11.3 0.1 2.2 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal TIP49 PF06068.13 KNZ78301.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AGT PF11440.8 KNZ78301.1 - 0.24 10.4 0.1 0.32 10.0 0.1 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Abhydrolase_1 PF00561.20 KNZ78302.1 - 1.6e-12 47.6 0.0 2.3e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ78302.1 - 3.6e-07 29.7 0.0 2.2e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KNZ78302.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 KNZ78302.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ndr PF03096.14 KNZ78302.1 - 0.082 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family 5-FTHF_cyc-lig PF01812.20 KNZ78303.1 - 5.7e-46 156.7 0.0 6.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PIG-P PF08510.12 KNZ78304.1 - 2.6e-31 108.0 11.1 4.3e-31 107.3 11.1 1.3 1 1 0 1 1 1 1 PIG-P DPM2 PF07297.12 KNZ78304.1 - 0.16 12.3 7.6 0.35 11.2 7.7 1.6 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2070 PF09843.9 KNZ78304.1 - 0.18 10.1 0.5 0.19 10.0 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-C2H2 PF00096.26 KNZ78305.1 - 4.6e-12 45.7 8.9 7.3e-07 29.3 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ78305.1 - 4e-07 30.3 6.9 0.00021 21.8 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ78305.1 - 0.00024 21.4 7.9 0.15 12.5 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 KNZ78305.1 - 0.0003 21.1 1.5 0.014 15.8 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KNZ78305.1 - 0.003 17.8 0.9 0.037 14.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KNZ78305.1 - 0.098 12.7 0.5 0.098 12.7 0.5 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 KNZ78305.1 - 0.56 10.3 3.0 5.8 7.0 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 KNZ78305.1 - 1.4 8.7 4.7 9.9 6.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain XPG_N PF00752.17 KNZ78306.1 - 6.5e-23 81.1 0.0 1.4e-22 80.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KNZ78306.1 - 1.7e-22 79.6 0.7 2.6e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 KNZ78306.1 - 2.5e-07 30.4 0.0 4.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KNZ78306.1 - 0.0023 18.5 0.0 0.0056 17.3 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 KNZ78306.1 - 0.086 13.0 0.2 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_5 PF14520.6 KNZ78306.1 - 0.15 12.7 0.5 0.97 10.1 0.0 2.6 4 0 0 4 4 4 0 Helix-hairpin-helix domain Myf5 PF12232.8 KNZ78306.1 - 0.31 11.9 2.4 1.1 10.0 2.4 1.9 1 0 0 1 1 1 0 Myogenic determination factor 5 Aldo_ket_red PF00248.21 KNZ78307.1 - 1e-24 87.3 0.0 9.9e-18 64.3 0.0 3.0 2 1 0 2 2 2 2 Aldo/keto reductase family HCMVantigenic_N PF12154.8 KNZ78309.1 - 0.029 14.5 2.0 0.11 12.6 2.0 2.0 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Y_phosphatase2 PF03162.13 KNZ78309.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family NAC PF01849.18 KNZ78310.1 - 1.2e-24 86.0 0.2 2e-24 85.3 0.2 1.4 1 0 0 1 1 1 1 NAC domain Acetyltransf_1 PF00583.25 KNZ78311.1 - 3.2e-13 49.9 0.0 4.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ78311.1 - 6.4e-07 29.7 0.0 8.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ78311.1 - 0.00024 21.1 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ78311.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Cofilin_ADF PF00241.20 KNZ78312.1 - 1.9e-25 89.0 0.4 2.3e-25 88.7 0.4 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein OstA_2 PF13100.6 KNZ78312.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 OstA-like protein Neugrin PF06413.11 KNZ78313.1 - 1.2e-13 51.6 0.8 1.6e-13 51.2 0.8 1.1 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 KNZ78313.1 - 2.2e-06 28.0 6.0 3e-06 27.5 6.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 KNZ78313.1 - 0.15 12.7 0.1 0.15 12.7 0.1 2.7 1 1 1 2 2 2 0 Homeodomain-like domain p450 PF00067.22 KNZ78314.1 - 8.1e-33 113.9 0.0 2.1e-32 112.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.20 KNZ78315.1 - 1.4e-18 67.5 3.0 1.6e-18 67.3 3.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related CLTH PF10607.9 KNZ78316.1 - 5.9e-34 117.1 0.3 1.1e-33 116.2 0.3 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain RT_RNaseH PF17917.1 KNZ78317.1 - 1e-05 25.8 0.2 2.4e-05 24.6 0.1 1.6 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78317.1 - 0.0075 16.3 0.1 0.014 15.4 0.1 1.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PIG-S PF10510.9 KNZ78319.1 - 2.7e-96 323.5 2.4 3.2e-96 323.2 2.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Myb_DNA-binding PF00249.31 KNZ78320.1 - 1.4e-17 63.6 0.0 1e-07 32.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ78320.1 - 1.2e-10 41.5 0.0 0.00099 19.3 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KNZ78320.1 - 6.2e-07 29.2 0.1 0.00014 21.7 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like Cadherin_C_2 PF16492.5 KNZ78320.1 - 0.17 12.6 1.8 0.34 11.7 0.4 2.2 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Rotamase_3 PF13616.6 KNZ78321.1 - 3.7e-19 69.4 0.0 6.8e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 KNZ78321.1 - 1.5e-15 57.9 0.0 2.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KNZ78321.1 - 3.7e-05 24.5 0.1 6.2e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain ABC_tran PF00005.27 KNZ78322.1 - 3.7e-31 108.5 0.2 1.1e-16 61.5 0.0 3.1 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KNZ78322.1 - 2.6e-14 52.8 5.4 5.9e-14 51.6 5.4 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 KNZ78322.1 - 1.8e-11 44.4 2.4 0.18 11.6 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNZ78322.1 - 2.8e-11 43.3 5.4 0.0003 20.3 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 KNZ78322.1 - 8.3e-07 28.6 3.1 8.3e-07 28.6 3.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 KNZ78322.1 - 1.7e-05 24.8 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KNZ78322.1 - 6.6e-05 23.4 0.0 0.3 11.5 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KNZ78322.1 - 8.5e-05 23.0 0.0 0.22 12.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 KNZ78322.1 - 0.00015 21.6 0.3 0.23 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KNZ78322.1 - 0.00036 20.8 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 KNZ78322.1 - 0.00041 20.3 1.6 0.00041 20.3 1.6 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.12 KNZ78322.1 - 0.00046 20.1 0.7 0.056 13.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 KNZ78322.1 - 0.00048 20.3 0.1 0.18 12.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KNZ78322.1 - 0.00094 18.9 0.5 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 KNZ78322.1 - 0.001 18.8 0.1 0.32 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 KNZ78322.1 - 0.002 18.7 0.4 0.002 18.7 0.4 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain TsaE PF02367.17 KNZ78322.1 - 0.0024 17.9 0.8 0.23 11.5 0.0 3.1 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 KNZ78322.1 - 0.0026 18.0 0.0 1.1 9.5 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 KNZ78322.1 - 0.0038 16.4 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Fer4_10 PF13237.6 KNZ78322.1 - 0.0039 17.3 14.8 0.0058 16.7 1.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KNZ78322.1 - 0.0052 16.9 11.4 0.011 15.9 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 KNZ78322.1 - 0.0062 16.6 0.6 0.0062 16.6 0.6 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 KNZ78322.1 - 0.0062 16.5 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_21 PF14697.6 KNZ78322.1 - 0.0065 16.6 11.8 0.013 15.6 11.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 KNZ78322.1 - 0.0068 16.8 0.2 2.3 8.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.6 KNZ78322.1 - 0.0074 16.6 0.3 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 KNZ78322.1 - 0.008 16.4 0.5 0.071 13.3 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 KNZ78322.1 - 0.011 15.4 2.1 0.9 9.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KNZ78322.1 - 0.015 15.8 0.9 7.9 7.0 0.0 3.2 2 1 0 3 3 3 0 AAA domain Fer4_16 PF13484.6 KNZ78322.1 - 0.025 15.5 0.3 0.025 15.5 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_7 PF12775.7 KNZ78322.1 - 0.031 13.8 1.0 0.33 10.5 0.1 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribosomal_L30 PF00327.20 KNZ78322.1 - 0.04 13.8 0.0 9.6 6.2 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e MMR_HSR1 PF01926.23 KNZ78322.1 - 0.043 13.9 0.2 7.8 6.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 KNZ78322.1 - 0.052 13.5 0.9 0.96 9.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KNZ78322.1 - 0.063 12.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein VirE PF05272.11 KNZ78322.1 - 0.071 12.8 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_14 PF13173.6 KNZ78322.1 - 0.095 12.7 1.6 10 6.2 0.0 3.3 2 2 1 3 3 3 0 AAA domain AAA_30 PF13604.6 KNZ78322.1 - 0.12 12.1 0.6 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 KNZ78322.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 KNZ78322.1 - 0.2 10.3 1.8 0.66 8.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 KNZ78322.1 - 0.7 10.4 9.8 0.37 11.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.7 KNZ78322.1 - 1.6 9.4 14.2 0.36 11.5 2.9 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 KNZ78322.1 - 6.5 7.4 12.3 0.072 13.6 1.0 2.5 1 1 2 3 3 2 0 4Fe-4S dicluster domain LIM PF00412.22 KNZ78323.1 - 1.2e-07 31.8 12.2 5.8e-05 23.2 0.4 2.9 2 1 0 2 2 2 2 LIM domain VirionAssem_T7 PF11653.8 KNZ78323.1 - 0.14 12.7 0.2 0.35 11.4 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Astro_capsid_p PF12226.8 KNZ78323.1 - 0.37 9.9 2.7 0.63 9.1 2.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2321 PF10083.9 KNZ78323.1 - 1.7 8.3 3.4 3.6 7.2 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DZR PF12773.7 KNZ78323.1 - 5.5 7.1 10.7 3.9e+02 1.2 10.7 2.9 1 1 0 1 1 1 0 Double zinc ribbon Mob1_phocein PF03637.17 KNZ78324.1 - 1.5e-63 213.8 0.1 1.8e-63 213.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family WW PF00397.26 KNZ78327.1 - 0.074 13.1 5.8 0.65 10.1 0.1 2.8 2 0 0 2 2 2 0 WW domain XPG_I PF00867.18 KNZ78328.1 - 8.3e-15 54.9 0.0 1.6e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KNZ78328.1 - 2.7e-05 24.5 0.0 5.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc_N PF02739.16 KNZ78328.1 - 0.0033 17.3 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain Coatomer_WDAD PF04053.14 KNZ78330.1 - 1.3e-136 456.3 0.0 3e-136 455.0 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 KNZ78330.1 - 2.2e-114 382.4 0.0 3e-114 381.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KNZ78330.1 - 4.8e-44 147.5 17.0 3.8e-08 33.8 0.4 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78330.1 - 1.4e-10 41.3 0.1 0.017 15.4 0.0 5.7 4 1 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_14 PF13428.6 KNZ78330.1 - 0.00078 20.1 2.9 6.7 7.8 0.0 4.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ78330.1 - 0.006 16.6 1.6 0.39 10.9 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Nup160 PF11715.8 KNZ78330.1 - 0.011 14.4 3.7 3 6.4 0.0 4.1 4 1 1 5 5 5 0 Nucleoporin Nup120/160 PspA_IM30 PF04012.12 KNZ78330.1 - 0.15 11.6 0.6 0.35 10.4 0.6 1.5 1 0 0 1 1 1 0 PspA/IM30 family 2-Hacid_dh_C PF02826.19 KNZ78331.1 - 8.3e-40 136.0 0.0 1.2e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNZ78331.1 - 2.9e-21 75.5 0.0 3.5e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNZ78331.1 - 0.0029 17.8 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 KNZ78331.1 - 0.099 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Flavoprotein PF02441.19 KNZ78333.1 - 7e-51 172.1 0.0 8.2e-51 171.9 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein NDUFA12 PF05071.16 KNZ78334.1 - 0.012 16.5 7.9 0.078 13.8 7.9 2.0 1 1 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 PCI PF01399.27 KNZ78335.1 - 2.5e-22 79.3 0.4 1.3e-21 77.1 0.0 2.3 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.11 KNZ78335.1 - 2.5e-21 75.8 0.5 9.2e-21 74.1 0.1 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 KNZ78335.1 - 0.11 12.6 3.6 0.17 12.0 1.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Herpes_Helicase PF02689.14 KNZ78337.1 - 2.9e-07 28.8 0.0 3.1e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ78337.1 - 0.0012 18.7 0.1 0.0034 17.2 0.1 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Ank_2 PF12796.7 KNZ78338.1 - 8e-06 26.4 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ78338.1 - 8.1e-06 25.8 0.1 0.0059 17.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KNZ78338.1 - 1e-05 25.7 0.2 0.00037 20.7 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KNZ78338.1 - 0.0018 18.6 0.4 0.054 14.0 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KNZ78338.1 - 0.017 15.7 0.5 0.088 13.4 0.5 2.0 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Ssu72 PF04722.13 KNZ78338.1 - 0.042 13.4 1.9 0.061 12.9 1.9 1.5 1 1 0 1 1 1 0 Ssu72-like protein ENTH PF01417.20 KNZ78339.1 - 7.3e-31 106.8 2.1 1.1e-30 106.3 2.1 1.3 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 KNZ78339.1 - 0.0069 16.2 0.6 0.0069 16.2 0.6 3.3 3 0 0 3 3 3 1 Ubiquitin interaction motif Sec2p PF06428.11 KNZ78339.1 - 0.0085 16.0 1.0 0.0085 16.0 1.0 2.5 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p ANTH PF07651.16 KNZ78339.1 - 0.01 14.9 0.5 0.017 14.2 0.0 1.5 2 0 0 2 2 2 0 ANTH domain GST_C_3 PF14497.6 KNZ78339.1 - 0.053 13.7 1.0 0.083 13.1 0.1 1.8 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Porph_ging PF09697.10 KNZ78339.1 - 0.78 10.3 3.6 6.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Cys_Met_Meta_PP PF01053.20 KNZ78341.1 - 1e-21 76.9 0.1 1.4e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4078 PF13300.6 KNZ78341.1 - 0.093 13.1 1.5 0.16 12.3 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) PIF1 PF05970.14 KNZ78342.1 - 6.1e-06 25.6 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Glyco_hydro_47 PF01532.20 KNZ78343.1 - 5.8e-110 368.3 0.0 7.7e-73 245.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Ribophorin_II PF05817.14 KNZ78344.1 - 2.5e-32 112.3 0.0 2.8e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Skp1_POZ PF03931.15 KNZ78345.1 - 0.0018 18.4 0.0 0.0039 17.3 0.0 1.6 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain FAD_oxidored PF12831.7 KNZ78346.1 - 0.13 11.6 0.1 0.15 11.4 0.1 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_47 PF01532.20 KNZ78347.1 - 2.9e-120 402.3 0.0 3.5e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 KNZ78348.1 - 5.1e-127 424.5 0.0 6e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sec20 PF03908.13 KNZ78350.1 - 5.9e-18 64.6 2.8 2.1e-17 62.8 2.8 2.0 1 0 0 1 1 1 1 Sec20 Baculo_11_kDa PF06143.11 KNZ78350.1 - 0.097 12.3 0.1 0.26 10.9 0.1 1.8 1 0 0 1 1 1 0 Baculovirus 11 kDa family Apq12 PF12716.7 KNZ78350.1 - 0.17 11.9 5.3 0.34 10.9 5.3 1.4 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis DUF5082 PF16888.5 KNZ78350.1 - 1.3 9.3 7.0 2.2 8.6 2.7 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) RRM_1 PF00076.22 KNZ78351.1 - 3.3e-52 174.2 0.0 1.1e-16 60.4 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ78351.1 - 0.001 19.2 0.0 6.7 6.9 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif Afaf PF15339.6 KNZ78351.1 - 1.4 8.6 0.0 1.4 8.6 0.0 3.4 4 0 0 4 4 4 0 Acrosome formation-associated factor Syntaxin-6_N PF09177.11 KNZ78352.1 - 8e-24 84.1 1.3 8e-24 84.1 1.3 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 KNZ78352.1 - 2.8e-08 33.6 0.6 2.8e-08 33.6 0.6 2.2 3 0 0 3 3 2 1 SNARE domain Use1 PF09753.9 KNZ78352.1 - 2e-06 27.7 1.1 2.4e-06 27.5 1.1 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4407 PF14362.6 KNZ78352.1 - 0.00021 20.8 3.1 0.0018 17.7 3.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Prominin PF05478.11 KNZ78352.1 - 0.00066 17.8 1.2 0.032 12.2 0.1 2.2 2 0 0 2 2 2 2 Prominin DUF3040 PF11239.8 KNZ78352.1 - 0.0044 17.2 0.0 0.01 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) ALC PF17527.2 KNZ78352.1 - 0.052 13.2 0.1 0.097 12.3 0.1 1.4 1 0 0 1 1 1 0 Phage ALC protein MetOD2 PF18548.1 KNZ78352.1 - 0.095 12.8 2.9 0.86 9.8 0.2 3.1 3 1 1 4 4 4 0 Metanogen output domain 2 SlyX PF04102.12 KNZ78352.1 - 0.16 12.6 9.5 28 5.4 0.1 4.1 3 1 1 4 4 4 0 SlyX Trans_reg_C PF00486.28 KNZ78352.1 - 0.19 11.8 1.1 0.59 10.2 0.1 2.4 3 1 0 3 3 2 0 Transcriptional regulatory protein, C terminal Spc7 PF08317.11 KNZ78352.1 - 0.2 10.5 6.4 0.33 9.8 0.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein FPP PF05911.11 KNZ78352.1 - 0.23 9.6 5.8 1.2 7.3 0.3 2.0 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil Lebercilin PF15619.6 KNZ78352.1 - 0.31 10.7 8.8 0.15 11.7 1.0 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Enkurin PF13864.6 KNZ78352.1 - 0.32 11.5 4.1 6.4 7.3 0.6 3.0 2 1 0 2 2 2 0 Calmodulin-binding DUF5446 PF17522.2 KNZ78352.1 - 0.41 10.8 0.1 0.41 10.8 0.1 2.5 3 0 0 3 3 2 0 Family of unknown function (DUF5446) Seryl_tRNA_N PF02403.22 KNZ78352.1 - 0.65 10.2 3.6 1.7 8.9 0.4 2.7 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 KNZ78352.1 - 0.79 9.9 5.5 5.5 7.2 0.1 3.5 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 MnmE_helical PF12631.7 KNZ78352.1 - 1.5 8.9 4.7 2.6 8.2 4.7 1.4 1 1 0 1 1 1 0 MnmE helical domain FlaC_arch PF05377.11 KNZ78352.1 - 1.9 8.9 4.6 9.1 6.8 0.2 3.3 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) Nup88 PF10168.9 KNZ78352.1 - 3.4 5.4 6.5 3.8 5.2 0.7 2.0 2 0 0 2 2 2 0 Nuclear pore component CENP-F_leu_zip PF10473.9 KNZ78352.1 - 3.8 7.5 9.0 2 8.5 1.0 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG17 PF04108.12 KNZ78352.1 - 4.2 6.4 12.5 7.3 5.6 1.0 3.0 2 1 0 3 3 3 0 Autophagy protein Apg17 DivIC PF04977.15 KNZ78352.1 - 7.6 6.4 6.7 4 7.3 1.3 2.9 2 1 1 3 3 3 0 Septum formation initiator Chromo PF00385.24 KNZ78353.1 - 4.5e-07 29.7 0.1 1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 KNZ78353.1 - 0.0054 16.6 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 PHD-finger ApoLp-III PF07464.11 KNZ78353.1 - 0.029 14.5 5.0 0.1 12.7 5.0 1.9 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4142 PF13628.6 KNZ78353.1 - 0.19 12.0 7.7 0.047 13.9 3.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) AAA_13 PF13166.6 KNZ78353.1 - 0.21 10.2 2.3 0.35 9.4 2.3 1.2 1 0 0 1 1 1 0 AAA domain Phage_GPO PF05929.11 KNZ78353.1 - 7.4 6.1 9.9 0.36 10.4 4.2 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FMO-like PF00743.19 KNZ78355.1 - 1.5e-43 149.0 0.0 9.2e-32 110.2 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KNZ78355.1 - 3.6e-18 65.9 0.0 4e-14 52.6 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KNZ78355.1 - 1.1e-08 34.7 0.0 5.3e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ78355.1 - 1.3e-08 35.0 2.0 0.0038 17.2 0.0 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 KNZ78355.1 - 2.9e-06 26.7 0.1 0.00031 20.0 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KNZ78355.1 - 0.0004 20.6 0.1 0.004 17.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ78355.1 - 0.021 14.4 5.3 0.37 10.3 0.1 3.5 3 2 1 4 4 4 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KNZ78355.1 - 0.024 13.9 0.2 9.3 5.4 0.0 2.8 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 KNZ78355.1 - 0.088 12.0 0.1 0.66 9.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 KNZ78355.1 - 0.089 13.2 0.2 9 6.8 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 KNZ78355.1 - 0.13 11.4 1.6 5.7 6.1 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KNZ78355.1 - 0.16 12.6 0.1 20 5.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TMEM154 PF15102.6 KNZ78356.1 - 0.24 11.3 3.3 0.28 11.1 0.1 2.4 1 1 0 2 2 2 0 TMEM154 protein family G_path_suppress PF15991.5 KNZ78356.1 - 0.72 9.9 7.2 0.72 9.9 3.3 2.1 2 0 0 2 2 2 0 G-protein pathway suppressor Sterol_MT_C PF08498.10 KNZ78357.1 - 1e-18 67.4 0.2 2.1e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 KNZ78357.1 - 1.3e-18 67.2 0.0 2.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ78357.1 - 7.1e-17 61.9 0.0 2.2e-16 60.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ78357.1 - 3.4e-15 56.5 0.0 7.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ78357.1 - 5.8e-14 52.3 0.0 1.9e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KNZ78357.1 - 2e-13 50.3 0.1 4e-13 49.3 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KNZ78357.1 - 3.6e-11 43.7 0.0 1.5e-10 41.7 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ78357.1 - 1.3e-06 27.9 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 KNZ78357.1 - 4.9e-05 22.6 0.0 0.00015 21.0 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_15 PF09445.10 KNZ78357.1 - 0.00025 20.7 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 KNZ78357.1 - 0.00032 20.5 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 KNZ78357.1 - 0.0031 17.1 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KNZ78357.1 - 0.0051 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KNZ78357.1 - 0.0077 17.2 0.0 0.038 15.0 0.0 2.2 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KNZ78357.1 - 0.011 15.1 0.2 0.024 13.9 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain UPF0020 PF01170.18 KNZ78357.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF1518 PF07469.12 KNZ78357.1 - 1.6 9.2 8.1 0.11 13.0 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) FGE-sulfatase PF03781.16 KNZ78358.1 - 2e-23 83.3 0.8 6.6e-21 75.0 0.8 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KNZ78358.1 - 5.8e-06 26.8 0.4 2e-05 25.1 0.3 1.9 2 0 0 2 2 2 1 DinB superfamily CASP_C PF08172.12 KNZ78358.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 CASP C terminal MFS_1 PF07690.16 KNZ78359.1 - 6e-22 78.0 26.2 6.8e-22 77.9 25.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF308 PF03729.13 KNZ78359.1 - 3.3 8.1 12.8 0.15 12.4 5.1 2.8 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Cupin_1 PF00190.22 KNZ78360.1 - 3.4e-30 104.7 0.1 3.3e-19 69.0 0.0 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KNZ78360.1 - 5.9e-16 58.0 4.0 1.3e-11 44.0 0.9 2.7 2 1 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KNZ78360.1 - 2.4e-05 23.9 0.1 0.041 13.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 KNZ78360.1 - 0.00012 22.0 0.0 0.0004 20.3 0.0 1.7 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.12 KNZ78360.1 - 0.01 15.4 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_8 PF13621.6 KNZ78360.1 - 0.068 12.9 0.1 12 5.5 0.0 2.2 2 0 0 2 2 2 0 Cupin-like domain DUF1971 PF09313.11 KNZ78360.1 - 0.09 12.8 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) CENP-C_C PF11699.8 KNZ78360.1 - 0.11 12.7 0.0 7.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Mif2/CENP-C like AraC_binding PF02311.19 KNZ78360.1 - 0.19 11.6 0.3 3.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Mad3_BUB1_I PF08311.12 KNZ78361.1 - 7.1e-33 113.2 0.0 1.2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Cyclin_N2 PF16500.5 KNZ78361.1 - 0.017 15.9 0.5 0.053 14.3 0.0 2.0 2 0 0 2 2 2 0 N-terminal region of cyclin_N Herpes_capsid PF06112.11 KNZ78361.1 - 1.3 9.1 12.5 2.4 8.2 12.5 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein RRM_1 PF00076.22 KNZ78362.1 - 3.7e-26 90.8 0.0 6.7e-17 61.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KNZ78362.1 - 3.2e-08 33.6 0.0 1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.6 KNZ78362.1 - 0.0071 16.3 0.0 0.039 14.0 0.0 2.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF374 PF04028.13 KNZ78364.1 - 0.055 13.0 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Zn_Tnp_IS1595 PF12760.7 KNZ78365.1 - 0.0013 18.6 1.1 0.0025 17.8 0.5 1.8 1 1 0 1 1 1 1 Transposase zinc-ribbon domain zf-RVT PF13966.6 KNZ78365.1 - 0.0024 18.5 2.9 0.0052 17.5 0.7 2.0 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase TF_Zn_Ribbon PF08271.12 KNZ78365.1 - 0.053 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2834 PF11196.8 KNZ78368.1 - 1.4e-06 28.5 17.7 0.00017 21.9 2.4 4.1 4 1 1 5 5 5 3 Protein of unknown function (DUF2834) Glyco_hydro_61 PF03443.14 KNZ78369.1 - 1.6e-64 217.7 0.0 3.3e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KNZ78369.1 - 1.4e-12 47.3 7.7 1.4e-12 47.3 7.7 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain MCM2_N PF12619.8 KNZ78370.1 - 0.058 13.7 1.3 0.083 13.2 1.3 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 HD-ZIP_N PF04618.12 KNZ78370.1 - 1.3 9.5 13.9 1.8 9.1 2.4 3.8 3 1 0 3 3 3 0 HD-ZIP protein N terminus Ras PF00071.22 KNZ78372.1 - 2.4e-37 128.0 0.0 5.7e-35 120.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KNZ78372.1 - 8.1e-28 97.1 0.0 1.7e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ78372.1 - 2.9e-07 30.1 0.0 8.3e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ78372.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ78372.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNZ78372.1 - 0.0025 17.4 0.0 0.015 14.9 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KNZ78372.1 - 0.14 12.1 0.1 1.6 8.6 0.3 2.6 3 1 0 3 3 3 0 RsgA GTPase Peptidase_S10 PF00450.22 KNZ78375.1 - 1.4e-82 278.3 0.0 1.8e-82 278.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UbiA PF01040.18 KNZ78379.1 - 8.1e-21 74.5 6.9 9.6e-21 74.2 6.9 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family TraL PF07178.11 KNZ78379.1 - 2.9 8.4 6.1 3.4 8.2 1.3 2.4 2 0 0 2 2 2 0 TraL protein Abhydrolase_6 PF12697.7 KNZ78380.1 - 5.4e-11 43.5 0.2 2.4e-09 38.2 0.1 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KNZ78380.1 - 0.028 13.3 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 KNZ78380.1 - 0.05 13.2 0.0 0.61 9.7 0.0 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KNZ78380.1 - 0.18 11.6 0.1 0.59 9.9 0.1 1.9 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PigN PF04987.14 KNZ78381.1 - 7.5e-104 348.1 40.1 9.6e-104 347.8 40.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 KNZ78381.1 - 2.8e-11 43.6 0.2 3.7e-08 33.4 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KNZ78381.1 - 1.6e-05 24.5 0.0 3.6e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 KNZ78381.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF4059 PF13268.6 KNZ78381.1 - 0.05 14.0 1.3 0.23 11.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) PglZ PF08665.12 KNZ78381.1 - 0.17 11.9 0.5 0.33 11.0 0.1 1.6 2 0 0 2 2 2 0 PglZ domain p450 PF00067.22 KNZ78385.1 - 2.8e-61 207.7 0.0 3.9e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.6 KNZ78386.1 - 4.8e-16 59.6 0.0 7.4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ78386.1 - 8.8e-13 48.6 0.0 1.5e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KNZ78387.1 - 4.8e-36 124.5 0.0 1.3e-35 123.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Asp_protease_2 PF13650.6 KNZ78389.1 - 0.089 13.4 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease NAD_binding_4 PF07993.12 KNZ78390.1 - 7.8e-26 90.8 0.0 1.4e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ78390.1 - 1.4e-21 76.6 0.0 1.6e-19 69.8 0.0 2.9 2 1 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KNZ78390.1 - 1.5e-09 37.7 0.0 2.6e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 KNZ78390.1 - 0.021 15.0 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus PP-binding PF00550.25 KNZ78390.1 - 0.077 13.4 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Arch_fla_DE PF04659.13 KNZ78390.1 - 0.1 12.4 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Archaeal flagella protein RmlD_sub_bind PF04321.17 KNZ78390.1 - 0.11 11.6 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Rrn6 PF10214.9 KNZ78391.1 - 1.4e-10 40.4 6.1 4.8e-09 35.3 0.3 3.2 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Stevor PF17410.2 KNZ78392.1 - 0.0018 17.9 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame TMEM154 PF15102.6 KNZ78392.1 - 0.0031 17.4 0.2 0.0031 17.4 0.2 1.7 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.16 KNZ78392.1 - 0.0031 16.3 0.1 0.0043 15.9 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF2185 PF09951.9 KNZ78392.1 - 0.015 15.1 0.0 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) DUF4448 PF14610.6 KNZ78392.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Orf78 PF06024.12 KNZ78392.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 KNZ78392.1 - 0.14 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF515 PF04415.12 KNZ78392.1 - 1.5 7.2 10.1 2.5 6.4 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mito_carr PF00153.27 KNZ78393.1 - 7.7e-45 150.8 0.4 3.6e-16 58.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Cpn60_TCP1 PF00118.24 KNZ78394.1 - 7.1e-142 473.5 12.3 8.1e-142 473.3 12.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SAF PF08666.12 KNZ78394.1 - 0.019 15.5 0.1 0.052 14.2 0.1 1.7 1 0 0 1 1 1 0 SAF domain HSL_N PF06350.12 KNZ78394.1 - 0.088 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus UFD1 PF03152.14 KNZ78395.1 - 3.4e-70 235.0 0.0 4.4e-70 234.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 WLM PF08325.10 KNZ78395.1 - 0.38 10.8 4.4 2.8 8.0 0.3 2.2 2 0 0 2 2 2 0 WLM domain NMT_C PF02799.15 KNZ78396.1 - 4.2e-80 268.2 0.0 6.8e-80 267.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KNZ78396.1 - 4.2e-73 244.5 0.1 6.2e-73 243.9 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 KNZ78396.1 - 5.2e-05 23.3 0.0 0.00036 20.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ78396.1 - 0.0076 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family HSP20 PF00011.21 KNZ78397.1 - 8.4e-23 80.5 0.1 1.1e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ78397.1 - 4.3e-10 39.0 0.0 6.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KNZ78397.1 - 0.11 13.5 0.0 0.17 12.9 0.0 1.3 1 0 0 1 1 1 0 CS domain ING PF12998.7 KNZ78398.1 - 4.7e-17 62.4 0.4 7.2e-17 61.8 0.4 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KNZ78398.1 - 7.5e-06 25.8 8.1 1.2e-05 25.1 8.1 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KNZ78398.1 - 0.085 12.4 2.6 0.16 11.6 2.6 1.4 1 0 0 1 1 1 0 PHD-finger TMCO5 PF14992.6 KNZ78398.1 - 0.11 12.0 0.3 0.28 10.7 0.2 1.6 2 0 0 2 2 2 0 TMCO5 family DUF2203 PF09969.9 KNZ78398.1 - 0.16 12.7 0.1 0.32 11.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 KNZ78398.1 - 0.17 12.4 4.5 1.5 9.4 1.4 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region Lzipper-MIP1 PF14389.6 KNZ78398.1 - 1.7 9.0 4.8 8.8 6.7 0.3 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 OGG_N PF07934.12 KNZ78399.1 - 4e-34 117.3 0.0 6.2e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KNZ78399.1 - 7.9e-16 58.5 0.0 1.4e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KNZ78399.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif NPR2 PF06218.11 KNZ78400.1 - 2.5e-73 247.3 4.9 3.8e-33 114.9 0.3 4.1 1 1 1 3 3 3 3 Nitrogen permease regulator 2 ThiF PF00899.21 KNZ78401.1 - 1.9e-45 155.1 0.0 2.5e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KNZ78401.1 - 4.1e-27 94.1 1.1 6.5e-27 93.5 1.1 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.9 KNZ78401.1 - 0.11 12.4 0.3 7.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site RTC PF01137.21 KNZ78402.1 - 8.5e-58 195.2 0.0 9.9e-58 195.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KNZ78402.1 - 5.7e-34 116.7 0.0 1.1e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Sirohm_synth_C PF14823.6 KNZ78403.1 - 1.7e-20 72.4 0.1 2.9e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KNZ78403.1 - 9.9e-14 50.5 0.0 2.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 KNZ78403.1 - 7.5e-12 45.6 0.1 3.7e-11 43.4 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Torus PF16131.5 KNZ78404.1 - 9.7e-07 29.5 0.1 1.6e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 KNZ78404.1 - 1e-05 25.4 3.0 3.5e-05 23.7 3.0 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_3 PF15663.5 KNZ78404.1 - 0.00031 20.9 0.3 0.001 19.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH PF00642.24 KNZ78404.1 - 0.0014 18.5 2.5 0.0039 17.1 2.5 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KNZ78404.1 - 0.011 15.5 1.9 0.032 14.1 1.9 1.8 1 0 0 1 1 1 0 CCCH-type zinc finger RRM_1 PF00076.22 KNZ78404.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 KNZ78404.1 - 0.047 14.2 2.7 0.11 13.0 2.7 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Sulf_transp PF04143.14 KNZ78405.1 - 2.4e-09 37.2 8.4 2.4e-09 37.2 8.4 2.5 2 1 0 2 2 2 2 Sulphur transport LEA_2 PF03168.13 KNZ78406.1 - 0.00028 21.4 0.1 0.00056 20.4 0.1 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 KNZ78406.1 - 0.046 13.0 0.3 0.07 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) TSC22 PF01166.18 KNZ78407.1 - 0.00027 21.2 0.1 0.00054 20.2 0.1 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 KNZ78407.1 - 0.0074 16.9 1.0 0.015 15.9 1.0 1.5 1 0 0 1 1 1 1 Initiation control protein YabA HALZ PF02183.18 KNZ78407.1 - 0.039 14.2 1.8 0.062 13.5 1.8 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 KNZ78407.1 - 0.2 11.8 4.0 0.36 11.0 4.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 KNZ78407.1 - 0.93 10.0 6.2 0.16 12.4 2.3 1.7 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 KNZ78407.1 - 1.7 8.5 4.0 3.5 7.5 4.0 1.5 1 0 0 1 1 1 0 Septum formation initiator JmjC PF02373.22 KNZ78408.1 - 1.4e-14 54.5 0.1 3.5e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Pkinase PF00069.25 KNZ78410.1 - 1.5e-26 93.3 0.0 1.8e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78410.1 - 4.4e-13 49.1 0.0 5.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ78410.1 - 1.4e-07 30.7 0.0 1.8e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ78410.1 - 0.02 14.8 0.0 3.7 7.4 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family FMO-like PF00743.19 KNZ78411.1 - 4.1e-12 45.3 0.6 4.2e-10 38.7 0.6 2.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KNZ78411.1 - 2.1e-11 43.6 0.2 2.9e-10 39.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KNZ78411.1 - 5.1e-11 42.6 0.1 1.5e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KNZ78411.1 - 1.8e-10 40.5 0.0 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ78411.1 - 1.4e-09 37.6 0.2 1.1e-08 34.7 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ78411.1 - 4.1e-05 23.3 0.4 0.00064 19.4 0.2 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KNZ78411.1 - 0.00082 18.5 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ78411.1 - 0.0025 16.9 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KNZ78411.1 - 0.0036 16.6 0.0 0.0083 15.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KNZ78411.1 - 0.007 16.4 0.0 0.041 13.9 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 KNZ78411.1 - 0.016 14.3 1.0 0.33 10.0 0.5 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KNZ78411.1 - 0.11 11.8 0.7 0.15 11.4 0.2 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Vac_ImportDeg PF09783.9 KNZ78412.1 - 7.9e-51 172.1 0.0 3.1e-50 170.1 0.0 1.8 1 1 0 1 1 1 1 Vacuolar import and degradation protein MFS_1 PF07690.16 KNZ78413.1 - 6.3e-45 153.6 52.1 3.8e-44 151.0 51.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KNZ78413.1 - 6.5e-16 57.9 15.8 9.3e-16 57.4 15.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KNZ78413.1 - 2.2e-13 49.9 9.5 2.2e-13 49.9 9.5 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.8 KNZ78413.1 - 0.0015 17.3 0.2 0.0015 17.3 0.2 2.7 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like MFS_2 PF13347.6 KNZ78413.1 - 0.012 14.1 32.5 0.016 13.8 9.9 3.4 2 2 0 3 3 3 0 MFS/sugar transport protein Ras PF00071.22 KNZ78414.1 - 2.7e-50 170.1 0.1 7.5e-50 168.7 0.0 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KNZ78414.1 - 2.6e-30 105.1 0.2 7.8e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ78414.1 - 3.2e-10 39.8 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ78414.1 - 0.00075 18.9 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ78414.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KNZ78414.1 - 0.0017 17.6 0.6 0.29 10.2 0.1 2.4 2 1 0 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 KNZ78414.1 - 0.0096 15.8 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 KNZ78414.1 - 0.022 14.3 0.2 0.044 13.3 0.1 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 KNZ78414.1 - 0.025 14.0 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein TsaE PF02367.17 KNZ78414.1 - 0.028 14.4 0.1 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KNZ78414.1 - 0.033 14.6 0.1 0.28 11.6 0.1 2.2 1 1 0 1 1 1 0 RNA helicase DUF5118 PF17162.4 KNZ78414.1 - 0.051 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 KNZ78414.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 KNZ78414.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KNZ78414.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KNZ78414.1 - 0.17 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain FRG1 PF06229.12 KNZ78416.1 - 1.1e-29 103.5 0.0 1.8e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KNZ78416.1 - 0.0044 17.2 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Fascin domain BRF1 PF07741.13 KNZ78416.1 - 0.74 10.2 10.7 0.98 9.8 6.7 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain Ribosomal_L26 PF16906.5 KNZ78417.1 - 5.4e-37 126.1 4.4 8.3e-37 125.5 4.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KNZ78417.1 - 3.6e-09 36.3 4.2 7.7e-09 35.2 4.2 1.6 1 0 0 1 1 1 1 KOW motif ATP-synt_D PF01813.17 KNZ78418.1 - 3.2e-71 239.2 4.3 3.8e-71 239.0 4.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit D H2O2_YaaD PF03883.14 KNZ78418.1 - 0.021 14.3 0.1 0.051 13.1 0.1 1.6 1 1 0 1 1 1 0 Peroxide stress protein YaaA XAP5 PF04921.14 KNZ78419.1 - 3e-88 295.8 4.7 3e-88 295.8 4.7 2.0 2 0 0 2 2 2 1 XAP5, circadian clock regulator T3SS_basalb_I PF17001.5 KNZ78419.1 - 0.36 11.4 3.0 2 9.1 0.3 2.6 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Ribosomal_S13 PF00416.22 KNZ78420.1 - 5.5e-20 72.0 0.0 7.9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KNZ78420.1 - 0.017 13.9 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 KNZ78420.1 - 0.044 14.1 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif TRAPP PF04051.16 KNZ78421.1 - 4.5e-33 114.0 0.0 5.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WBS_methylT PF12589.8 KNZ78422.1 - 7.8e-24 84.2 11.4 1.1e-23 83.7 11.4 1.2 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 KNZ78422.1 - 1.8e-09 38.1 0.0 3.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ78422.1 - 6.5e-08 33.2 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ78422.1 - 4.8e-05 24.0 0.0 0.00013 22.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ78422.1 - 0.00026 20.9 0.0 0.00038 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ78422.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 KNZ78422.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase BCS1_N PF08740.11 KNZ78423.1 - 1.7e-49 168.4 2.8 2.3e-49 167.9 2.8 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 KNZ78423.1 - 5.4e-19 68.9 0.0 9.3e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ78423.1 - 0.00025 21.5 0.0 0.00094 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KNZ78423.1 - 0.0004 20.0 0.0 0.0012 18.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNZ78423.1 - 0.0033 17.6 0.1 0.0099 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KNZ78423.1 - 0.0081 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KNZ78423.1 - 0.022 15.3 0.0 0.046 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KNZ78423.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 KNZ78423.1 - 0.036 14.3 0.1 0.18 12.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 KNZ78423.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 KNZ78423.1 - 0.048 13.7 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 KNZ78423.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ78423.1 - 0.053 13.9 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KNZ78423.1 - 0.065 13.1 0.0 1.2 9.0 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 KNZ78423.1 - 0.066 13.2 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 KNZ78423.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase PF06745.13 KNZ78423.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KNZ78423.1 - 0.097 13.2 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KNZ78423.1 - 0.1 12.3 0.1 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ank_4 PF13637.6 KNZ78424.1 - 2.6e-09 37.4 0.1 7.4e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ78424.1 - 2.9e-08 34.2 0.0 1.5e-06 28.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) DnaJ PF00226.31 KNZ78424.1 - 8e-08 32.3 0.2 3.4e-07 30.3 0.2 2.1 1 1 0 1 1 1 1 DnaJ domain Ank_3 PF13606.6 KNZ78424.1 - 7.4e-07 29.0 0.0 0.12 13.0 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KNZ78424.1 - 1.1e-06 28.7 0.1 0.00053 20.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KNZ78424.1 - 0.0042 17.5 0.0 1 10.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Presenilin PF01080.17 KNZ78424.1 - 6.5 5.4 7.8 11 4.7 7.8 1.3 1 0 0 1 1 1 0 Presenilin LUC7 PF03194.15 KNZ78425.1 - 8.1e-70 235.3 5.5 1.1e-69 234.9 5.5 1.1 1 0 0 1 1 1 1 LUC7 N_terminus LRS4 PF10422.9 KNZ78426.1 - 1.5 8.3 5.6 3.7 7.0 1.1 2.3 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 UCH PF00443.29 KNZ78427.1 - 1.1e-33 116.9 4.6 2.5e-33 115.7 4.6 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ78427.1 - 4.3e-17 62.7 7.0 1.7e-16 60.7 3.8 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KNZ78427.1 - 3.6e-06 26.6 0.1 9.1e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 KNZ78427.1 - 0.00064 20.3 0.0 0.029 15.0 0.0 3.0 2 0 0 2 2 2 1 DUSP domain Gaa1 PF04114.14 KNZ78428.1 - 7.7e-110 368.3 5.3 1.2e-108 364.4 5.3 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component SBP_bac_5 PF00496.22 KNZ78428.1 - 0.16 10.9 0.0 0.39 9.6 0.0 1.5 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 5 Middle TAFII55_N PF04658.13 KNZ78429.1 - 3.6e-55 186.1 0.3 6.5e-55 185.2 0.3 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Tom37 PF10568.9 KNZ78430.1 - 3e-30 105.1 0.8 4.8e-30 104.4 0.0 1.8 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 KNZ78430.1 - 2.9e-10 40.8 0.0 9e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KNZ78430.1 - 3.8e-07 29.8 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Exo_endo_phos PF03372.23 KNZ78433.1 - 4.1e-16 59.2 0.1 5.7e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RLL PF10036.9 KNZ78433.1 - 0.039 13.8 0.4 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein ABC_tran PF00005.27 KNZ78435.1 - 4e-32 111.6 1.7 5.3e-22 78.8 0.1 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KNZ78435.1 - 5.9e-12 45.5 0.8 2.9e-05 23.6 0.0 3.5 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KNZ78435.1 - 1.4e-07 31.6 8.4 0.0064 16.3 0.1 3.2 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 KNZ78435.1 - 1.1e-05 25.4 3.6 1.1e-05 25.4 3.6 2.2 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KNZ78435.1 - 0.0056 16.4 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 KNZ78435.1 - 0.073 13.0 0.1 4.9 7.0 0.1 2.9 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.27 KNZ78436.1 - 5.7e-21 75.5 0.0 7.8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KNZ78436.1 - 5.6e-06 26.4 0.1 0.0061 16.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNZ78436.1 - 3.4e-05 23.4 0.0 0.022 14.2 0.0 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KNZ78436.1 - 8.1e-05 22.4 0.0 0.00042 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ78436.1 - 0.00023 21.6 0.1 0.00036 20.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KNZ78436.1 - 0.00033 20.3 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KNZ78436.1 - 0.00055 19.9 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.6 KNZ78436.1 - 0.0026 18.3 0.0 0.0042 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KNZ78436.1 - 0.009 15.9 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase TsaE PF02367.17 KNZ78436.1 - 0.0095 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KNZ78436.1 - 0.018 15.0 0.1 0.097 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 KNZ78436.1 - 0.026 14.8 0.1 0.31 11.3 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KNZ78436.1 - 0.027 14.7 0.1 0.049 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KNZ78436.1 - 0.031 13.4 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF815 PF05673.13 KNZ78436.1 - 0.032 13.4 0.1 5.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 KNZ78436.1 - 0.033 13.4 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 KNZ78436.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KNZ78436.1 - 0.056 13.6 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KNZ78436.1 - 0.082 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.12 KNZ78436.1 - 0.09 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA PF00004.29 KNZ78436.1 - 0.11 12.9 0.0 1.3 9.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KNZ78436.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein CbiA PF01656.23 KNZ78436.1 - 0.12 12.5 0.3 0.28 11.2 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KNZ78436.1 - 0.13 11.9 0.2 0.7 9.4 0.1 1.9 1 1 1 2 2 2 0 AAA domain cobW PF02492.19 KNZ78436.1 - 0.15 11.6 0.1 0.32 10.6 0.1 1.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 KNZ78436.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 KNZ78436.1 - 0.33 9.6 0.0 10 4.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Snf7 PF03357.21 KNZ78437.1 - 6.6e-11 42.1 4.4 9.3e-11 41.6 4.4 1.2 1 0 0 1 1 1 1 Snf7 STAT_alpha PF01017.20 KNZ78437.1 - 0.074 12.9 1.2 0.094 12.6 0.2 1.6 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF2959 PF11172.8 KNZ78437.1 - 0.083 13.0 1.1 0.86 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) CdvA PF18822.1 KNZ78437.1 - 0.093 12.6 5.5 0.082 12.7 2.1 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain AKNA PF12443.8 KNZ78437.1 - 0.11 13.2 0.1 0.3 11.8 0.1 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor COG2 PF06148.11 KNZ78437.1 - 0.12 12.4 0.3 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 KNZ78437.1 - 0.79 10.2 4.7 3.1 8.3 0.1 3.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 KNZ78437.1 - 1.5 9.1 5.1 5.3 7.4 0.1 2.7 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GrpE PF01025.19 KNZ78437.1 - 2.4 7.8 6.2 0.18 11.5 0.9 1.8 2 0 0 2 2 2 0 GrpE Seryl_tRNA_N PF02403.22 KNZ78437.1 - 5 7.4 7.0 3.4 8.0 0.5 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SKG6 PF08693.10 KNZ78438.1 - 0.0045 16.4 1.2 0.0088 15.4 1.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 KNZ78438.1 - 0.076 13.5 1.8 0.08 13.4 0.2 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Ribosomal_L30_N PF08079.12 KNZ78439.1 - 1.5e-29 102.0 17.6 1.5e-29 102.0 17.6 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KNZ78439.1 - 4.2e-18 65.0 1.9 4.8e-18 64.8 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Pro_CA PF00484.19 KNZ78440.1 - 6.2e-34 117.5 0.5 3.5e-18 66.4 0.0 2.6 2 1 0 2 2 2 2 Carbonic anhydrase Exo_endo_phos PF03372.23 KNZ78441.1 - 1e-07 31.7 0.0 3.7e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family bZIP_1 PF00170.21 KNZ78442.1 - 0.041 14.0 1.8 0.12 12.5 1.8 1.8 1 0 0 1 1 1 0 bZIP transcription factor ADIP PF11559.8 KNZ78442.1 - 0.096 12.8 0.3 0.096 12.8 0.3 2.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Med9 PF07544.13 KNZ78442.1 - 0.63 10.2 3.7 0.69 10.1 0.4 2.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 SKIP_SNW PF02731.15 KNZ78443.1 - 9.8e-73 243.1 1.2 9.8e-73 243.1 1.2 1.8 2 0 0 2 2 2 1 SKIP/SNW domain DUF1682 PF07946.14 KNZ78443.1 - 9.4 5.3 18.4 17 4.5 18.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Tim54 PF11711.8 KNZ78444.1 - 5e-61 206.6 0.0 7.1e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Remorin_C PF03763.13 KNZ78444.1 - 0.025 14.4 0.3 0.048 13.5 0.3 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region DEAD PF00270.29 KNZ78445.1 - 3.1e-17 62.9 0.0 6.7e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 KNZ78445.1 - 8.5e-14 51.3 0.0 3e-08 33.1 0.0 2.4 1 1 1 2 2 2 2 Sec63 Brl domain ResIII PF04851.15 KNZ78445.1 - 3.8e-08 33.5 0.0 2.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNZ78445.1 - 2.5e-07 31.0 0.0 1.4e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CKS PF01111.19 KNZ78446.1 - 5.6e-36 122.6 0.2 7.1e-36 122.3 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16_M PF16187.5 KNZ78447.1 - 3.6e-93 311.9 0.1 5.4e-93 311.3 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 KNZ78447.1 - 9.9e-39 132.7 0.7 2.7e-38 131.3 0.4 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KNZ78447.1 - 1.2e-19 71.0 0.0 5.7e-10 39.5 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain ATP-synt_ab PF00006.25 KNZ78448.1 - 6.9e-63 212.1 0.0 1.1e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KNZ78448.1 - 1.6e-22 79.8 1.3 4.7e-22 78.3 1.3 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 KNZ78448.1 - 0.0048 16.1 0.9 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 KNZ78448.1 - 0.028 14.3 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 KNZ78448.1 - 0.033 14.1 0.0 0.073 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 KNZ78448.1 - 0.036 14.4 0.1 0.11 12.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 KNZ78448.1 - 0.039 14.4 0.0 0.41 11.1 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KNZ78448.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KNZ78448.1 - 0.072 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KNZ78448.1 - 0.086 13.2 0.6 0.31 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KNZ78449.1 - 9.6e-62 203.5 17.4 5.4e-11 42.9 0.0 8.1 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78449.1 - 2.4e-25 88.6 0.8 3.9e-07 30.3 0.0 6.1 2 2 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ78449.1 - 1.3e-09 37.3 7.8 0.013 14.1 0.1 5.4 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KNZ78449.1 - 3e-05 22.9 1.0 1.3 7.7 0.0 4.0 2 1 1 3 3 3 3 Nup133 N terminal like eIF2A PF08662.11 KNZ78449.1 - 0.00014 21.9 0.0 0.26 11.1 0.1 3.5 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KNZ78449.1 - 0.0006 18.4 0.4 0.071 11.6 0.1 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KNZ78449.1 - 0.0016 17.4 0.2 5.1 6.0 0.0 3.6 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1652 PF07865.11 KNZ78449.1 - 0.1 12.5 0.0 11 5.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) bZIP_2 PF07716.15 KNZ78449.1 - 0.11 12.6 0.6 0.2 11.8 0.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Zn_clus PF00172.18 KNZ78450.1 - 8.9e-10 38.5 12.1 1.3e-09 38.0 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ins_P5_2-kin PF06090.12 KNZ78451.1 - 1.5e-71 241.5 0.1 2e-71 241.2 0.1 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Acyl-CoA_dh_1 PF00441.24 KNZ78451.1 - 6.2e-40 136.9 0.2 1.2e-39 135.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KNZ78451.1 - 3.6e-31 108.1 0.0 8.2e-31 107.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KNZ78451.1 - 2e-21 76.0 0.0 7.3e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KNZ78451.1 - 4.8e-13 49.5 0.0 8.4e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DASH_Dad3 PF08656.10 KNZ78453.1 - 3.3e-20 71.9 0.1 4.2e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.32 KNZ78454.1 - 2.5e-15 56.6 9.3 0.0022 18.8 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78454.1 - 7.5e-13 48.6 0.0 0.00012 22.3 0.0 4.3 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 KNZ78454.1 - 0.00066 18.5 1.2 0.0077 15.0 0.9 2.8 2 1 1 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 KNZ78454.1 - 0.0025 17.7 0.0 1.8 8.6 0.0 3.1 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KNZ78454.1 - 0.0071 16.2 0.1 0.46 10.3 0.0 2.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A GATA PF00320.27 KNZ78455.1 - 2.9e-13 49.2 6.6 5e-13 48.4 6.6 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 KNZ78455.1 - 0.037 14.3 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 KNZ78455.1 - 0.065 13.2 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 PAS fold adh_short_C2 PF13561.6 KNZ78456.1 - 2e-54 184.6 0.2 2.7e-54 184.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ78456.1 - 1.4e-40 138.9 0.5 4.7e-40 137.1 0.6 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KNZ78456.1 - 4e-08 33.4 0.1 2.1e-07 31.0 0.0 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KNZ78456.1 - 0.0045 16.5 0.0 0.012 15.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KNZ78456.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family Kinesin PF00225.23 KNZ78457.1 - 7.4e-102 340.7 1.0 3.2e-101 338.6 0.0 2.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ78457.1 - 1.1e-23 83.9 0.0 4.3e-23 81.9 0.0 2.2 1 0 0 1 1 1 1 Microtubule binding FAM184 PF15665.5 KNZ78457.1 - 0.0014 18.4 23.0 0.0014 18.4 23.0 10.9 3 2 8 11 11 11 1 Family with sequence similarity 184, A and B Fib_alpha PF08702.10 KNZ78457.1 - 0.0017 18.5 2.6 0.0017 18.5 2.6 12.4 6 4 5 13 13 13 4 Fibrinogen alpha/beta chain family DUF641 PF04859.12 KNZ78457.1 - 0.0055 17.0 4.1 0.0055 17.0 4.1 12.9 6 3 7 15 15 15 3 Plant protein of unknown function (DUF641) Arginase PF00491.21 KNZ78458.1 - 2.4e-65 220.8 0.1 3.1e-65 220.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family Aminotran_1_2 PF00155.21 KNZ78459.1 - 1.6e-23 83.5 0.0 1.9e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CwfJ_C_1 PF04677.15 KNZ78460.1 - 8.7e-29 99.9 0.0 1.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 KNZ78460.1 - 1e-23 82.7 17.9 2.4e-11 43.2 2.6 3.5 3 0 0 3 3 3 3 Zinc knuckle CwfJ_C_2 PF04676.14 KNZ78460.1 - 1.1e-11 45.4 0.0 2.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC PF00098.23 KNZ78460.1 - 1.8e-09 37.2 11.8 6.5e-05 22.8 0.4 3.6 3 0 0 3 3 3 2 Zinc knuckle Zn_ribbon_SprT PF17283.2 KNZ78460.1 - 0.39 10.7 3.9 26 4.8 0.7 3.2 2 1 1 3 3 3 0 SprT-like zinc ribbon domain zf-CCHC_3 PF13917.6 KNZ78460.1 - 0.66 10.0 5.8 7.1 6.7 0.3 3.0 1 1 2 3 3 3 0 Zinc knuckle DUF4428 PF14471.6 KNZ78460.1 - 1.6 8.7 3.3 37 4.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) zinc-ribbons_6 PF07191.12 KNZ78460.1 - 1.6 8.7 6.7 5.2 7.1 1.5 2.4 1 1 1 2 2 2 0 zinc-ribbons TF_Zn_Ribbon PF08271.12 KNZ78460.1 - 3.4 7.2 13.0 7.9 6.1 0.8 3.4 3 0 0 3 3 3 0 TFIIB zinc-binding COesterase PF00135.28 KNZ78461.1 - 3.4e-55 187.9 0.0 1.5e-47 162.7 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ78461.1 - 5e-13 49.4 0.0 8.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 KNZ78461.1 - 0.0026 17.7 2.1 0.027 14.4 0.0 2.7 2 1 0 2 2 2 1 Cutinase NUDIX PF00293.28 KNZ78462.1 - 2e-11 44.1 0.0 1.1e-10 41.6 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain ubiquitin PF00240.23 KNZ78463.1 - 1.1e-06 28.2 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family NIF PF03031.18 KNZ78463.1 - 1.5e-05 24.8 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HATPase_c_2 PF13581.6 KNZ78463.1 - 0.089 12.8 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CSN8_PSD8_EIF3K PF10075.9 KNZ78464.1 - 2.1e-14 53.7 0.0 3.9e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF1439 PF07273.12 KNZ78464.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) DUF3866 PF12982.7 KNZ78464.1 - 0.093 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) DUF1681 PF07933.14 KNZ78465.1 - 6.5e-51 171.9 0.0 7.5e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Rab_eff_C PF04698.12 KNZ78465.1 - 0.025 12.9 0.0 0.029 12.7 0.0 1.0 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Glyco_hydro_6 PF01341.17 KNZ78466.1 - 1e-106 357.2 1.4 1.3e-106 356.8 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KNZ78466.1 - 1.1e-12 47.7 6.6 3.2e-12 46.2 6.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Aminotran_5 PF00266.19 KNZ78467.1 - 1e-92 311.0 0.0 1.2e-92 310.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V RRM_1 PF00076.22 KNZ78468.1 - 1.1e-29 102.1 0.0 4e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KNZ78468.1 - 0.00027 20.9 0.0 0.0061 16.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KNZ78468.1 - 0.0012 18.8 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif DbpA PF03880.15 KNZ78468.1 - 0.0088 16.0 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 2 DbpA RNA binding domain Limkain-b1 PF11608.8 KNZ78468.1 - 0.017 15.1 0.1 7.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 RRM_5 PF13893.6 KNZ78468.1 - 0.021 14.4 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KNZ78468.1 - 0.046 13.4 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 KNZ78468.1 - 0.097 12.5 0.0 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif CAP_GLY PF01302.25 KNZ78469.1 - 9.3e-20 70.4 0.3 2.9e-19 68.8 0.1 1.9 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 KNZ78469.1 - 2.2e-12 47.0 6.9 0.00016 22.0 0.1 5.1 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ78469.1 - 6.7e-08 32.2 8.7 0.00019 21.1 0.0 5.2 4 3 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 KNZ78469.1 - 1e-06 28.4 0.1 0.00012 21.6 0.0 2.7 1 1 2 3 3 3 2 Leucine-rich repeat ECH_2 PF16113.5 KNZ78470.1 - 7.2e-110 367.6 0.0 8.9e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KNZ78470.1 - 7.1e-26 91.0 0.0 7.3e-23 81.2 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SNAD3 PF18749.1 KNZ78470.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 IDO PF01231.18 KNZ78471.1 - 4.3e-119 398.2 0.0 5.1e-119 397.9 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Rep_fac-A_C PF08646.10 KNZ78472.1 - 1.2e-50 171.1 1.1 2.1e-49 167.0 0.7 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KNZ78472.1 - 9.6e-36 121.6 0.0 3e-35 120.0 0.0 1.9 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 KNZ78472.1 - 2.3e-18 66.1 0.0 7.3e-18 64.5 0.0 1.9 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KNZ78472.1 - 7e-14 51.6 0.1 2e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KNZ78472.1 - 0.00012 21.9 0.1 0.036 13.8 0.0 2.3 2 0 0 2 2 2 2 Cell division control protein 24, OB domain 3 DUF4539 PF15072.6 KNZ78472.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Tmpp129 PF10272.9 KNZ78473.1 - 0.23 10.7 1.7 0.36 10.1 1.7 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor ABC_membrane PF00664.23 KNZ78474.1 - 8.3e-74 248.7 22.6 7.3e-41 140.6 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ78474.1 - 1.4e-60 203.8 0.0 1.7e-33 116.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ78474.1 - 3.9e-15 55.9 0.6 0.00013 21.5 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KNZ78474.1 - 1e-08 35.8 0.5 0.011 16.2 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KNZ78474.1 - 1.8e-08 34.6 0.2 1.9 8.2 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KNZ78474.1 - 4.4e-08 32.7 0.2 0.016 15.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ78474.1 - 6.2e-07 29.8 0.2 0.13 12.5 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KNZ78474.1 - 2.8e-06 27.9 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KNZ78474.1 - 3.3e-06 27.0 0.1 7.1 6.3 0.0 4.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 KNZ78474.1 - 3.3e-06 26.9 0.1 0.023 14.4 0.0 3.1 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 KNZ78474.1 - 4.2e-06 27.0 0.2 0.039 14.0 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_25 PF13481.6 KNZ78474.1 - 2.6e-05 23.9 0.8 0.2 11.2 0.0 3.8 5 0 0 5 5 4 2 AAA domain AAA_5 PF07728.14 KNZ78474.1 - 2.9e-05 24.1 0.1 1.2 9.2 0.0 3.9 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KNZ78474.1 - 0.00011 22.1 0.0 0.34 10.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Sigma54_activat PF00158.26 KNZ78474.1 - 0.00035 20.3 0.0 1.7 8.3 0.0 3.5 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_33 PF13671.6 KNZ78474.1 - 0.00046 20.4 0.0 0.98 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 KNZ78474.1 - 0.00049 20.4 0.2 1.3 9.3 0.3 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KNZ78474.1 - 0.00058 19.7 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain G-alpha PF00503.20 KNZ78474.1 - 0.00076 18.7 0.0 0.56 9.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Zeta_toxin PF06414.12 KNZ78474.1 - 0.00085 18.6 0.1 1.3 8.3 0.2 2.4 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.20 KNZ78474.1 - 0.0012 18.8 0.2 2.2 8.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase CbiA PF01656.23 KNZ78474.1 - 0.0019 18.3 0.0 0.95 9.5 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.6 KNZ78474.1 - 0.0023 18.5 0.0 1.8 9.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KNZ78474.1 - 0.0026 17.2 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Mg_chelatase PF01078.21 KNZ78474.1 - 0.0041 16.5 0.0 0.84 9.0 0.0 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 KNZ78474.1 - 0.006 16.8 0.2 4.2 7.7 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 KNZ78474.1 - 0.008 15.9 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 KNZ78474.1 - 0.012 14.7 0.3 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.18 KNZ78474.1 - 0.018 14.8 0.0 4 7.1 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 KNZ78474.1 - 0.037 14.0 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 KNZ78474.1 - 0.039 14.1 0.1 18 5.4 0.0 3.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KNZ78474.1 - 0.045 13.3 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 KNZ78474.1 - 0.046 13.6 0.0 15 5.5 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 KNZ78474.1 - 0.057 13.0 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CPT PF07931.12 KNZ78474.1 - 0.061 13.2 0.2 12 5.7 0.2 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 KNZ78474.1 - 0.066 13.6 0.2 21 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 KNZ78474.1 - 0.073 11.9 0.8 0.17 10.7 0.0 2.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class RNA_helicase PF00910.22 KNZ78474.1 - 0.073 13.5 0.0 22 5.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KNZ78474.1 - 0.074 12.2 0.0 6.8 5.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KNZ78474.1 - 0.14 12.3 0.4 7.7 6.6 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATPase PF06745.13 KNZ78474.1 - 0.15 11.4 0.2 18 4.6 0.0 2.6 3 0 0 3 3 3 0 KaiC Thymidylate_kin PF02223.17 KNZ78474.1 - 0.18 11.5 0.0 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase DUF1776 PF08643.10 KNZ78475.1 - 2.2e-17 63.4 0.0 3.7e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) CPDase PF07823.11 KNZ78476.1 - 3.8e-15 56.1 0.0 3.6e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 KNZ78476.1 - 2.4e-07 30.8 0.0 2.8e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 KNZ78476.1 - 8.6e-05 22.7 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase HVSL PF09749.9 KNZ78476.1 - 0.1 12.0 0.0 5 6.5 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised conserved protein tRNA-synt_1c PF00749.21 KNZ78477.1 - 1.3e-108 362.6 0.1 1.7e-108 362.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KNZ78477.1 - 4e-36 124.5 0.3 6.7e-36 123.8 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 KNZ78477.1 - 0.00026 20.9 0.1 0.00065 19.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ78477.1 - 0.00031 20.9 0.1 0.002 18.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ78477.1 - 0.011 16.0 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KNZ78477.1 - 0.031 14.1 0.1 0.092 12.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 KNZ78477.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain APG9 PF04109.16 KNZ78478.1 - 1.1e-195 651.3 8.2 1.6e-195 650.7 8.2 1.3 1 0 0 1 1 1 1 Autophagy protein Apg9 HMGL-like PF00682.19 KNZ78478.1 - 1.3e-62 211.8 0.0 2.4e-62 210.9 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KNZ78478.1 - 3.3e-45 153.3 3.4 2e-23 82.8 0.1 2.4 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain Thiamine_BP PF01910.17 KNZ78479.1 - 1.5e-19 69.7 0.0 4.8e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 Thiamine-binding protein DNA_methylase PF00145.17 KNZ78480.1 - 1.4e-46 159.4 0.0 2.5e-45 155.3 0.0 2.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KNZ78480.1 - 1.3e-23 83.2 0.0 4e-14 52.5 0.0 2.6 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 KNZ78480.1 - 1.8e-06 28.1 0.0 3.9e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain MCM PF00493.23 KNZ78481.1 - 2.7e-104 347.2 0.0 5.7e-104 346.1 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNZ78481.1 - 1.7e-30 105.5 0.4 3.2e-30 104.6 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KNZ78481.1 - 8.7e-19 67.7 2.7 2.5e-18 66.3 2.7 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KNZ78481.1 - 1.1e-17 64.5 1.0 3.3e-17 63.0 1.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 KNZ78481.1 - 1.9e-08 34.4 0.0 5.8e-06 26.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 KNZ78481.1 - 1.3e-07 31.2 0.1 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_C PF13335.6 KNZ78481.1 - 0.00072 20.1 1.6 0.0037 17.9 0.9 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 KNZ78481.1 - 0.0027 17.5 0.1 0.0083 15.9 0.1 1.8 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 KNZ78481.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNZ78481.1 - 0.074 12.8 0.0 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TPR_21 PF09976.9 KNZ78481.1 - 0.079 12.7 3.8 1 9.0 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain AAA_16 PF13191.6 KNZ78481.1 - 0.24 11.8 3.1 4.7 7.6 0.0 3.3 3 1 0 4 4 4 0 AAA ATPase domain Peptidase_S8 PF00082.22 KNZ78482.1 - 1.6e-36 126.1 0.8 2.2e-36 125.7 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KNZ78482.1 - 3.8e-27 94.1 0.4 6.9e-27 93.3 0.4 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 KNZ78482.1 - 0.035 14.6 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal of Subtilase family DUF2914 PF11141.8 KNZ78482.1 - 0.092 12.5 0.5 0.22 11.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Peptidase_S8 PF00082.22 KNZ78483.1 - 1.6e-37 129.4 2.9 2.3e-37 128.9 2.9 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 KNZ78483.1 - 9.6e-27 92.8 0.1 2.7e-26 91.4 0.2 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain POT1PC PF16686.5 KNZ78484.1 - 3.6e-19 69.1 1.9 6.8e-09 35.8 0.4 4.2 2 2 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KNZ78484.1 - 3.7e-14 52.8 0.0 3.8e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Phosducin PF02114.16 KNZ78485.1 - 3e-17 62.4 0.8 5.1e-07 28.9 0.0 3.1 2 1 1 3 3 3 3 Phosducin DUF16 PF01519.16 KNZ78486.1 - 0.04 14.4 0.0 12 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 GMC_oxred_N PF00732.19 KNZ78487.1 - 1e-32 113.7 0.0 1.1e-25 90.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ78487.1 - 8e-25 88.0 0.0 1.4e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KNZ78487.1 - 0.00012 21.4 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ78487.1 - 0.00092 19.4 0.3 0.0025 18.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ78487.1 - 0.0057 15.7 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ78487.1 - 0.013 14.6 0.2 0.02 14.0 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 KNZ78487.1 - 0.026 13.8 0.0 8.5 5.5 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ78487.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 KNZ78487.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KNZ78487.1 - 0.16 11.6 0.1 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 KNZ78487.1 - 0.23 10.5 0.1 0.4 9.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A SMC_N PF02463.19 KNZ78488.1 - 8.2e-61 205.2 0.0 6.9e-41 140.1 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KNZ78488.1 - 1.1e-27 96.6 0.0 4.4e-27 94.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KNZ78488.1 - 6.8e-17 62.2 1.5 9.5e-08 32.2 1.3 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ78488.1 - 3.7e-15 56.5 35.4 1.9e-11 44.3 10.0 3.6 2 2 2 4 4 4 2 AAA ATPase domain AAA_23 PF13476.6 KNZ78488.1 - 5.6e-08 33.5 31.2 5.6e-08 33.5 31.2 5.9 2 2 1 3 3 1 1 AAA domain ABC_tran PF00005.27 KNZ78488.1 - 0.00071 20.1 13.8 0.12 12.9 2.2 4.7 2 2 0 3 3 3 2 ABC transporter FtsK_SpoIIIE PF01580.18 KNZ78488.1 - 0.0011 18.4 0.1 0.26 10.6 0.0 3.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family Tropomyosin_1 PF12718.7 KNZ78488.1 - 0.0093 16.1 5.8 0.0093 16.1 5.8 7.5 5 2 2 7 7 6 2 Tropomyosin like AAA_29 PF13555.6 KNZ78488.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 KNZ78488.1 - 0.013 15.6 3.2 0.013 15.6 3.2 6.4 4 2 1 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3606 PF12244.8 KNZ78488.1 - 0.015 15.2 0.7 1.8 8.6 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Filo_VP35 PF02097.15 KNZ78488.1 - 0.074 12.1 0.5 0.43 9.6 0.2 2.5 2 0 0 2 2 2 0 Filoviridae VP35 APG6_N PF17675.1 KNZ78488.1 - 0.098 13.2 102.1 0.048 14.2 5.7 7.8 4 2 3 7 7 6 0 Apg6 coiled-coil region UPF0184 PF03670.13 KNZ78488.1 - 0.37 11.2 11.8 2.7 8.4 0.6 4.8 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) Spc7 PF08317.11 KNZ78488.1 - 0.91 8.3 87.5 0.21 10.4 17.2 6.4 2 2 3 6 6 6 0 Spc7 kinetochore protein DUF87 PF01935.17 KNZ78488.1 - 1.2 9.2 0.0 1.2 9.2 0.0 6.0 5 1 1 6 6 6 0 Helicase HerA, central domain Sec34 PF04136.15 KNZ78488.1 - 1.4 8.8 41.1 0.068 13.1 2.9 6.5 5 1 1 6 6 6 0 Sec34-like family DUF4674 PF15719.5 KNZ78488.1 - 4.2 7.4 8.6 0.55 10.3 3.9 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4674) Coq4 PF05019.13 KNZ78489.1 - 5.1e-101 336.6 0.0 6e-101 336.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Pkinase PF00069.25 KNZ78490.1 - 0.039 13.3 0.0 0.1 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain DUF4208 PF13907.6 KNZ78490.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DNA_pol_A_exo1 PF01612.20 KNZ78491.1 - 5.5e-47 159.7 0.4 1e-46 158.8 0.4 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 KNZ78491.1 - 2.1e-13 50.1 0.1 5.1e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 HRDC domain PMC2NT PF08066.12 KNZ78491.1 - 1.1e-11 45.3 1.9 1.7e-10 41.4 0.9 3.4 3 1 0 3 3 3 1 PMC2NT (NUC016) domain Nucleoporin_FG PF13634.6 KNZ78491.1 - 7 7.6 7.0 1.5 9.7 2.7 2.1 2 0 0 2 2 2 0 Nucleoporin FG repeat region MFS_1 PF07690.16 KNZ78492.1 - 1.2e-08 34.3 7.0 6.1e-08 32.0 7.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 KNZ78494.1 - 2.3e-45 155.1 48.0 3.8e-44 151.1 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ78494.1 - 9.9e-08 31.3 27.2 1.5e-05 24.1 7.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter LAB_N PF07578.11 KNZ78494.1 - 0.0068 16.5 0.6 0.034 14.2 0.6 2.2 1 0 0 1 1 1 1 Lipid A Biosynthesis N-terminal domain Tail_VII PF17091.5 KNZ78494.1 - 0.31 11.0 2.4 0.84 9.6 0.8 2.5 2 0 0 2 2 2 0 Inovirus G7P protein CRAL_TRIO PF00650.20 KNZ78495.1 - 9e-23 80.7 0.0 1.4e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ78495.1 - 2.1e-06 27.8 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain RPAP3_C PF13877.6 KNZ78496.1 - 6.4e-15 55.5 0.0 1e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 KNZ78496.1 - 1.1e-14 53.5 1.2 5.1e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ78496.1 - 1.8e-11 43.2 1.3 0.00033 20.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ78496.1 - 6.5e-06 25.9 0.2 0.0044 17.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ78496.1 - 3.6e-05 24.3 0.6 0.00032 21.3 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ78496.1 - 4.6e-05 23.8 0.3 0.0045 17.5 0.2 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ78496.1 - 0.001 18.7 1.7 0.19 11.4 0.7 2.8 2 1 1 3 3 3 1 TPR repeat TPR_14 PF13428.6 KNZ78496.1 - 0.0027 18.4 0.4 0.26 12.2 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ78496.1 - 0.0099 15.8 0.2 13 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ78496.1 - 0.013 15.6 0.1 0.029 14.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ78496.1 - 0.033 14.5 0.8 0.7 10.2 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ78496.1 - 0.043 14.4 0.1 0.58 10.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ78496.1 - 0.089 12.0 0.0 1.6 7.9 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ78496.1 - 0.12 12.8 0.1 21 5.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_Helicase PF02689.14 KNZ78497.1 - 0.013 13.4 0.1 0.014 13.4 0.1 1.0 1 0 0 1 1 1 0 Helicase Ribosomal_S17 PF00366.20 KNZ78498.1 - 5.4e-21 74.5 1.0 7e-21 74.1 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 PP2C PF00481.21 KNZ78499.1 - 2e-35 122.6 0.0 3.5e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Prefoldin_2 PF01920.20 KNZ78499.1 - 2.3e-20 72.5 9.0 2.3e-20 72.5 9.0 1.7 1 1 0 1 1 1 1 Prefoldin subunit PapG_C PF03628.13 KNZ78499.1 - 0.17 11.8 0.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 PapG chaperone-binding domain DUF641 PF04859.12 KNZ78499.1 - 0.24 11.8 8.0 0.77 10.1 1.8 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Rx_N PF18052.1 KNZ78499.1 - 3.7 7.9 9.1 0.51 10.6 1.1 2.4 2 0 0 2 2 2 0 Rx N-terminal domain Snf7 PF03357.21 KNZ78500.1 - 5e-28 97.8 7.6 5.6e-28 97.7 7.6 1.0 1 0 0 1 1 1 1 Snf7 PT-HINT PF07591.11 KNZ78500.1 - 0.12 12.6 0.3 0.16 12.2 0.3 1.2 1 0 0 1 1 1 0 Pretoxin HINT domain Pro_isomerase PF00160.21 KNZ78501.1 - 9.7e-43 146.2 0.0 1.5e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KNZ78501.1 - 0.038 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-NOSIP PF15906.5 KNZ78501.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein PPR_2 PF13041.6 KNZ78502.1 - 4.8e-40 135.5 0.0 1.9e-06 27.9 0.0 9.9 6 3 5 11 11 11 9 PPR repeat family PPR_3 PF13812.6 KNZ78502.1 - 2.2e-27 94.9 0.0 5.7e-07 29.5 0.0 7.1 3 2 4 8 8 8 7 Pentatricopeptide repeat domain PPR PF01535.20 KNZ78502.1 - 8.3e-18 63.3 2.9 0.092 13.0 0.0 10.0 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.7 KNZ78502.1 - 3.8e-17 61.7 0.0 0.075 12.8 0.0 8.4 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 KNZ78502.1 - 2.4e-11 43.4 0.0 0.00045 19.6 0.0 3.3 2 2 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP DUF3038 PF11237.8 KNZ78502.1 - 0.084 12.9 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) Kin17_mid PF10357.9 KNZ78503.1 - 1.4e-44 151.0 1.0 1e-38 132.1 0.2 2.3 2 0 0 2 2 2 2 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 KNZ78503.1 - 0.00032 20.9 3.9 0.00069 19.8 3.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNZ78503.1 - 0.00036 20.8 2.5 0.0006 20.1 0.6 2.1 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KNZ78503.1 - 0.00039 20.7 5.5 0.0011 19.3 5.5 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF4355 PF14265.6 KNZ78503.1 - 0.39 11.0 8.3 6.9 6.9 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Sugar_tr PF00083.24 KNZ78504.1 - 3.2e-103 346.0 13.4 6.1e-103 345.1 13.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ78504.1 - 3.6e-28 98.5 27.6 5.4e-19 68.3 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DEAD PF00270.29 KNZ78505.1 - 2.8e-21 76.1 0.0 1e-20 74.2 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78505.1 - 7e-09 36.0 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78505.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF4203 PF13886.6 KNZ78506.1 - 2e-47 161.5 29.2 2.9e-47 161.0 29.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) LAG1-DNAbind PF09271.11 KNZ78506.1 - 6.3e-27 95.1 0.0 1.5e-15 58.1 0.1 2.9 1 1 1 2 2 2 2 LAG1, DNA binding BTD PF09270.10 KNZ78506.1 - 2.2e-22 80.0 0.0 4.5e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain PK PF00224.21 KNZ78507.1 - 6.1e-156 518.6 0.2 7.6e-156 518.3 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KNZ78507.1 - 5.8e-36 123.3 0.0 1.3e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KNZ78507.1 - 0.00011 21.5 0.5 0.00024 20.3 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KNZ78507.1 - 0.022 13.8 0.2 0.16 10.9 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF4154 PF13689.6 KNZ78507.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 YfiR/HmsC-like Gly_transf_sug PF04488.15 KNZ78508.1 - 2.9e-05 24.6 0.0 6.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KNZ78508.1 - 0.095 12.1 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribul_P_3_epim PF00834.19 KNZ78509.1 - 1.1e-61 207.7 0.0 1.3e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.10 KNZ78509.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Cyclin_C_2 PF16899.5 KNZ78511.1 - 1.6e-16 60.6 1.7 1.7e-14 54.0 0.0 2.9 3 0 0 3 3 3 1 Cyclin C-terminal domain Cyclin_N PF00134.23 KNZ78511.1 - 1.4e-09 37.7 0.3 4.6e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 KNZ78511.1 - 0.00042 20.3 0.0 0.053 13.6 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat TFIIB_C_1 PF18542.1 KNZ78511.1 - 0.044 13.8 0.4 18 5.4 1.4 2.4 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 Sde2_N_Ubi PF13019.6 KNZ78511.1 - 2.7 7.8 7.7 2.3 8.0 5.6 2.0 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain RINGv PF12906.7 KNZ78512.1 - 3.8e-12 46.1 4.8 6.3e-12 45.4 4.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KNZ78512.1 - 0.0027 18.0 6.0 0.004 17.5 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KNZ78512.1 - 0.13 12.1 2.4 0.25 11.2 2.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF5345 PF17280.2 KNZ78512.1 - 0.29 11.1 2.5 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) PHD PF00628.29 KNZ78512.1 - 0.82 9.6 4.1 1.3 8.9 4.1 1.4 1 0 0 1 1 1 0 PHD-finger Mito_carr PF00153.27 KNZ78513.1 - 9.1e-40 134.5 0.0 2.6e-14 52.9 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_T PF00929.24 KNZ78514.1 - 8.8e-06 26.4 0.0 9.8e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Exonuclease DUF3025 PF11227.8 KNZ78514.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) GSH-S_N PF02951.14 KNZ78515.1 - 0.056 13.6 0.2 0.12 12.5 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain Cut8 PF08559.10 KNZ78516.1 - 3.1e-14 53.2 0.0 6.6e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein DUF4745 PF15923.5 KNZ78516.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) PRIMA1 PF16101.5 KNZ78516.1 - 7.1 6.7 11.8 16 5.5 11.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 KNZ78516.1 - 9.3 6.2 12.0 4.9 7.2 9.3 1.8 1 1 1 2 2 2 0 Mitochondrial fission regulator Cas1_AcylT PF07779.12 KNZ78517.1 - 1.4e-140 469.4 22.2 1.7e-140 469.1 22.2 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 KNZ78517.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Rhomboid PF01694.22 KNZ78518.1 - 4.2e-27 95.0 13.4 4.2e-27 95.0 13.4 1.7 1 1 1 2 2 2 1 Rhomboid family DIL PF01843.19 KNZ78519.1 - 7.1e-27 93.7 0.9 1.5e-26 92.7 0.3 1.9 2 0 0 2 2 2 1 DIL domain Ank_4 PF13637.6 KNZ78519.1 - 3.2e-06 27.6 0.0 6.3e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ78519.1 - 7.8e-06 26.4 0.0 2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KNZ78519.1 - 1.9e-05 24.9 0.3 0.02 15.3 0.2 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KNZ78519.1 - 0.00022 21.5 0.0 0.0006 20.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ78519.1 - 0.00032 20.9 0.0 0.0073 16.7 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Rrp15p PF07890.12 KNZ78520.1 - 1.1e-26 93.8 12.7 1.2e-25 90.4 12.7 2.0 1 1 0 1 1 1 1 Rrp15p RE_XcyI PF09571.10 KNZ78520.1 - 0.016 14.5 0.2 0.02 14.2 0.2 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease SIR4_SID PF16991.5 KNZ78520.1 - 0.059 13.4 8.8 0.025 14.7 5.5 2.0 2 1 0 2 2 2 0 Sir4 SID domain Pkinase PF00069.25 KNZ78521.1 - 1.8e-64 217.7 0.0 2.5e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78521.1 - 6.1e-45 153.5 0.0 9.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ78521.1 - 7.2e-10 38.6 0.0 6.3e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ras_bdg_2 PF14847.6 KNZ78521.1 - 2.9e-05 24.3 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Pkinase_fungal PF17667.1 KNZ78521.1 - 0.0017 17.2 0.0 0.0038 16.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KNZ78521.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF866 PF05907.13 KNZ78522.1 - 1.2e-37 129.2 0.0 1.3e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF4379 PF14311.6 KNZ78522.1 - 0.059 13.7 0.2 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 Probable Zinc-ribbon domain MRP-S28 PF10213.9 KNZ78523.1 - 8.2e-29 100.6 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Septin PF00735.18 KNZ78524.1 - 4.3e-116 387.1 0.0 4.3e-116 387.1 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KNZ78524.1 - 8.8e-07 29.0 0.2 3.2e-06 27.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ78524.1 - 5e-05 23.3 6.4 0.00088 19.2 0.0 3.2 3 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 KNZ78524.1 - 9.1e-05 22.1 3.1 0.027 14.0 0.0 3.2 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KNZ78524.1 - 0.00023 21.4 0.1 0.0037 17.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ78524.1 - 0.0022 18.4 0.0 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 KNZ78524.1 - 0.0097 16.4 5.5 0.19 12.3 0.5 2.8 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 KNZ78524.1 - 0.022 14.5 0.0 0.06 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ78524.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KNZ78524.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 KNZ78524.1 - 0.19 11.8 3.8 9.3 6.3 0.0 3.2 2 1 0 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 KNZ78524.1 - 0.33 10.5 3.6 0.59 9.6 3.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATPase_2 PF01637.18 KNZ78524.1 - 0.5 10.2 5.0 0.5 10.2 0.1 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea THOC7 PF05615.13 KNZ78524.1 - 0.55 10.5 0.1 0.55 10.5 0.1 2.6 2 1 0 2 2 1 0 Tho complex subunit 7 Atg14 PF10186.9 KNZ78524.1 - 0.59 9.2 5.0 0.88 8.6 5.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1764 PF08576.10 KNZ78524.1 - 0.94 10.4 6.2 11 7.0 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Strep_SA_rep PF06696.11 KNZ78524.1 - 4.2 7.5 12.4 0.43 10.6 3.4 2.7 1 1 1 2 2 2 0 Streptococcal surface antigen repeat ATP_bind_1 PF03029.17 KNZ78524.1 - 4.9 6.9 7.4 1.4 8.6 0.1 3.1 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Xpo1 PF08389.12 KNZ78525.1 - 3e-20 72.8 0.3 7.1e-19 68.3 0.1 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KNZ78525.1 - 5.9e-07 29.3 0.1 9.7e-06 25.4 0.0 2.9 2 1 1 3 3 3 1 Importin-beta N-terminal domain DUF3730 PF12530.8 KNZ78525.1 - 0.023 14.2 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) PUL PF08324.11 KNZ78525.1 - 0.026 13.7 0.1 0.08 12.2 0.1 1.8 1 0 0 1 1 1 0 PUL domain UME PF08064.13 KNZ78525.1 - 0.13 12.2 0.4 1.7 8.6 0.2 3.0 3 0 0 3 3 3 0 UME (NUC010) domain CoA_binding PF02629.19 KNZ78526.1 - 9e-30 103.2 1.6 1.1e-29 102.9 0.2 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KNZ78526.1 - 4.9e-23 81.6 0.0 7.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KNZ78526.1 - 5.9e-10 39.1 0.0 1.5e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KNZ78526.1 - 0.0052 17.3 0.4 0.025 15.0 0.0 2.3 2 1 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 KNZ78526.1 - 0.14 13.0 0.0 0.36 11.7 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ACBP PF00887.19 KNZ78527.1 - 1.7e-17 63.4 0.0 2.7e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.7 KNZ78527.1 - 5.7e-17 62.1 0.0 1.8e-08 34.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ78527.1 - 3.8e-13 49.6 0.0 3.3e-06 27.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ78527.1 - 1.7e-11 44.1 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KNZ78527.1 - 8.3e-08 32.3 0.1 3.1e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 KNZ78527.1 - 9.4e-08 31.8 0.1 4.6e-06 26.6 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ribosomal_S16 PF00886.19 KNZ78528.1 - 1.2e-16 60.5 0.1 2.6e-16 59.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S16 LSM PF01423.22 KNZ78529.1 - 4.9e-17 61.4 0.1 5.4e-17 61.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain Arm PF00514.23 KNZ78530.1 - 1.3e-93 304.5 13.8 4.7e-13 48.7 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KNZ78530.1 - 1.4e-22 79.7 4.5 7.1e-09 36.0 0.1 5.7 4 2 2 6 6 6 4 HEAT-like repeat IBB PF01749.20 KNZ78530.1 - 2e-22 79.4 0.8 4.1e-22 78.4 0.8 1.6 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 KNZ78530.1 - 1.6e-21 75.6 0.4 3.5e-21 74.5 0.4 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 KNZ78530.1 - 5.9e-20 71.5 1.5 4.6e-06 26.9 0.0 5.7 2 1 5 7 7 7 6 HEAT repeats HEAT PF02985.22 KNZ78530.1 - 5.3e-16 57.4 0.3 0.00031 20.7 0.0 6.5 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.13 KNZ78530.1 - 7.2e-06 25.6 0.0 0.26 10.7 0.0 4.1 2 1 1 4 4 4 2 Armadillo-like RICTOR_V PF14668.6 KNZ78530.1 - 9.7e-06 25.7 1.0 0.013 15.7 0.0 4.1 3 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 KNZ78530.1 - 1.2e-05 24.1 0.0 0.0017 17.0 0.0 2.7 1 1 2 3 3 3 1 Adaptin N terminal region HEAT_PBS PF03130.16 KNZ78530.1 - 0.00041 20.8 2.4 0.49 11.2 0.2 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 KNZ78530.1 - 0.00066 19.1 0.0 0.0036 16.7 0.0 2.0 2 0 0 2 2 2 1 Mo25-like V-ATPase_H_C PF11698.8 KNZ78530.1 - 0.00096 19.3 0.2 1.3 9.2 0.0 4.0 3 3 3 6 6 6 2 V-ATPase subunit H V-ATPase_H_N PF03224.14 KNZ78530.1 - 0.058 12.7 0.0 7.2 5.8 0.0 3.0 1 1 0 2 2 2 0 V-ATPase subunit H DUF3552 PF12072.8 KNZ78530.1 - 0.84 9.0 6.1 1.4 8.3 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) 2-Hacid_dh_C PF02826.19 KNZ78531.1 - 3.8e-58 195.8 0.1 5.7e-58 195.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNZ78531.1 - 2.1e-11 43.6 0.0 2.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNZ78531.1 - 0.00014 22.0 0.0 0.00039 20.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Axin_b-cat_bind PF08833.10 KNZ78531.1 - 0.01 15.9 0.7 0.088 12.9 0.1 2.3 2 0 0 2 2 2 0 Axin beta-catenin binding domain RPN2_C PF18004.1 KNZ78532.1 - 7.3e-41 139.7 2.3 6.8e-39 133.4 2.9 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KNZ78532.1 - 1.1e-32 110.8 24.0 3.7e-08 33.4 0.0 9.1 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KNZ78532.1 - 1.2e-17 64.1 0.1 9.6e-14 51.5 0.0 4.5 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KNZ78532.1 - 7.1e-05 22.7 0.2 3.5 8.1 0.1 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KNZ78532.1 - 0.00077 19.9 0.2 1.1 9.9 0.0 4.3 2 1 1 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 KNZ78532.1 - 0.01 15.8 0.0 13 5.8 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Clathrin_H_link PF13838.6 KNZ78532.1 - 0.14 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Clathrin-H-link Adaptin_N PF01602.20 KNZ78532.1 - 0.17 10.4 0.1 1.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Adaptin N terminal region ANAPC3 PF12895.7 KNZ78532.1 - 0.44 10.8 1.9 0.87 9.9 0.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Nucleoporin_N PF08801.11 KNZ78533.1 - 1.1e-48 166.1 0.0 1.6e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 KNZ78533.1 - 1.2e-36 126.6 1.0 1.9e-36 126.0 1.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal NAD_binding_6 PF08030.12 KNZ78534.1 - 3.5e-23 82.5 0.0 7.2e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KNZ78534.1 - 3e-21 75.6 0.0 7.5e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KNZ78534.1 - 1.4e-18 67.2 13.2 1.4e-18 67.2 13.2 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 KNZ78534.1 - 0.0019 18.8 0.0 0.038 14.6 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 KNZ78534.1 - 0.049 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HORMA PF02301.18 KNZ78535.1 - 1.8e-16 60.4 0.8 4.5e-16 59.1 0.8 1.6 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KNZ78535.1 - 0.0018 18.3 1.6 0.013 15.5 1.6 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 Arcadin_1 PF18653.1 KNZ78535.1 - 0.0021 18.1 1.3 0.0036 17.4 1.1 1.5 1 1 0 1 1 1 1 Arcadin 1 WD40 PF00400.32 KNZ78536.1 - 3.1e-44 148.1 13.1 1.5e-08 35.1 0.5 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KNZ78536.1 - 3.9e-28 98.3 0.0 6.6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KNZ78536.1 - 3.9e-10 39.9 0.0 0.00077 19.7 0.0 5.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KNZ78536.1 - 0.00042 19.1 1.4 0.39 9.3 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ELYS-bb PF16687.5 KNZ78536.1 - 0.032 12.9 0.1 0.38 9.3 0.0 2.1 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin eIF2A PF08662.11 KNZ78536.1 - 0.036 13.9 0.0 9 6.1 0.0 2.4 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 KNZ78536.1 - 0.071 13.1 0.0 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 LisH OKR_DC_1 PF01276.20 KNZ78537.1 - 0.016 14.0 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain EphA2_TM PF14575.6 KNZ78538.1 - 0.14 13.1 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 KNZ78538.1 - 0.63 10.5 13.2 0.049 14.1 6.4 2.2 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KNZ78539.1 - 1.6e-05 24.8 0.2 1.6e-05 24.8 0.2 1.7 1 1 1 2 2 2 1 TMEM154 protein family SKG6 PF08693.10 KNZ78539.1 - 0.0053 16.1 5.0 0.01 15.2 5.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KNZ78539.1 - 0.0064 17.3 0.0 0.011 16.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain UPF0515 PF15135.6 KNZ78539.1 - 0.0099 15.3 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 NCU-G1 PF15065.6 KNZ78539.1 - 0.01 14.9 0.1 0.017 14.2 0.1 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 Amnionless PF14828.6 KNZ78539.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Sulf_transp PF04143.14 KNZ78539.1 - 0.022 14.4 1.3 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 Sulphur transport Mid2 PF04478.12 KNZ78539.1 - 0.026 14.4 0.2 0.056 13.3 0.2 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TrbC PF04956.13 KNZ78539.1 - 0.037 14.2 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 TrbC/VIRB2 family MGC-24 PF05283.11 KNZ78539.1 - 0.045 14.2 1.3 0.045 14.2 1.3 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5305 PF17231.2 KNZ78539.1 - 0.085 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MLANA PF14991.6 KNZ78539.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A Chisel PF15355.6 KNZ78539.1 - 0.13 12.5 0.1 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel Gram_pos_anchor PF00746.21 KNZ78539.1 - 0.16 12.0 0.8 0.68 9.9 0.8 2.2 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF5385 PF17359.2 KNZ78539.1 - 0.27 10.8 0.0 0.39 10.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Podoplanin PF05808.11 KNZ78539.1 - 1.9 8.5 6.2 0.18 11.9 1.3 1.7 2 0 0 2 2 2 0 Podoplanin Meth_synt_2 PF01717.18 KNZ78540.1 - 7.5e-17 61.6 0.0 7.5e-16 58.3 0.0 2.2 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KNZ78540.1 - 0.0049 16.4 0.0 0.078 12.5 0.0 2.5 3 0 0 3 3 3 1 Cobalamin-independent synthase, N-terminal domain Tom5 PF10642.9 KNZ78540.1 - 0.21 11.6 0.2 0.51 10.4 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Ribosomal_L13e PF01294.18 KNZ78541.1 - 6.9e-76 254.1 7.8 1.1e-75 253.5 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e FA_desaturase PF00487.24 KNZ78542.1 - 3e-17 63.3 14.2 3.5e-17 63.1 14.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase His_biosynth PF00977.21 KNZ78543.1 - 1.1e-44 152.7 1.8 4.5e-44 150.6 1.8 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KNZ78543.1 - 3.2e-20 72.7 0.0 6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KNZ78543.1 - 5.8e-09 35.8 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 KNZ78543.1 - 0.00086 19.2 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_S51 PF03575.17 KNZ78543.1 - 0.087 12.5 0.0 0.29 10.7 0.0 1.8 3 0 0 3 3 3 0 Peptidase family S51 Peptidase_C26 PF07722.13 KNZ78543.1 - 0.13 12.0 0.8 1.6 8.4 0.8 2.2 1 1 0 1 1 1 0 Peptidase C26 2-Hacid_dh_C PF02826.19 KNZ78544.1 - 7.6e-53 178.5 0.0 3.2e-52 176.5 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNZ78544.1 - 9.7e-34 115.9 0.0 1.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNZ78544.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rad51 PF08423.11 KNZ78545.1 - 1e-125 418.2 0.0 1.2e-125 417.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KNZ78545.1 - 1.8e-10 40.7 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KNZ78545.1 - 3.1e-08 33.4 0.0 4.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KNZ78545.1 - 1.9e-07 31.6 0.3 1.9e-07 31.6 0.3 2.0 3 0 0 3 3 3 1 Helix-hairpin-helix domain ATPase PF06745.13 KNZ78545.1 - 0.00016 21.1 0.0 0.00033 20.1 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KNZ78545.1 - 0.15 11.4 0.0 0.7 9.2 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain F-box-like PF12937.7 KNZ78546.1 - 2.1e-05 24.3 0.2 0.00011 22.1 0.1 2.4 2 0 0 2 2 2 1 F-box-like UBZ_FAAP20 PF15750.5 KNZ78546.1 - 0.008 16.1 0.2 0.65 10.0 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-binding zinc-finger Ribosomal_L4 PF00573.22 KNZ78547.1 - 1.2e-59 201.2 0.0 1.5e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family TetR_C_20 PF17925.1 KNZ78547.1 - 0.065 13.6 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_S9 PF00380.19 KNZ78548.1 - 3.3e-27 95.4 0.3 1e-26 93.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S9/S16 BRCT_2 PF16589.5 KNZ78548.1 - 5.7e-21 74.7 0.0 1.6e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Tim17 PF02466.19 KNZ78549.1 - 1.1e-05 25.8 9.4 1.5e-05 25.3 9.2 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 KNZ78550.1 - 2.9e-07 31.0 6.5 0.0022 18.8 0.0 4.6 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF1648 PF07853.11 KNZ78551.1 - 4.8e-07 29.3 0.1 0.74 9.5 0.0 5.1 2 1 3 5 5 5 2 Protein of unknown function (DUF1648) DUF1722 PF08349.11 KNZ78551.1 - 0.0004 20.7 0.0 2.4 8.5 0.0 3.5 1 1 1 4 4 4 2 Protein of unknown function (DUF1722) NUC153 PF08159.12 KNZ78552.1 - 2.4e-13 49.6 12.5 1.7e-12 46.9 0.9 4.0 3 0 0 3 3 3 3 NUC153 domain PINIT PF14324.6 KNZ78554.1 - 4.1e-35 121.3 1.8 7e-35 120.5 1.8 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KNZ78554.1 - 2.1e-05 24.2 3.1 4.8e-05 23.0 3.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger DUF445 PF04286.12 KNZ78554.1 - 0.11 12.2 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SAP PF02037.27 KNZ78554.1 - 0.17 11.7 0.1 3 7.7 0.1 2.4 2 0 0 2 2 2 0 SAP domain Mito_carr PF00153.27 KNZ78555.1 - 5e-66 218.7 5.0 9.4e-24 83.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_88 PF07470.13 KNZ78555.1 - 0.13 11.3 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 ResIII PF04851.15 KNZ78556.1 - 1.8e-20 73.6 0.0 3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNZ78556.1 - 1.3e-16 60.9 0.2 5e-16 59.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNZ78556.1 - 9.5e-15 54.8 0.0 1.8e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KNZ78556.1 - 0.001 17.9 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ERCC3_RAD25_C PF16203.5 KNZ78556.1 - 0.0015 17.8 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 KNZ78556.1 - 0.0024 18.2 0.0 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD_2 PF06733.15 KNZ78556.1 - 0.0065 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 SWI2_SNF2 PF18766.1 KNZ78556.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KNZ78556.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 KNZ78556.1 - 0.021 13.9 0.0 0.056 12.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein OapA PF04225.12 KNZ78556.1 - 0.14 12.3 0.0 0.63 10.2 0.0 2.0 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain AAA_11 PF13086.6 KNZ78556.1 - 0.14 11.9 0.0 7.1 6.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain Indigoidine_A PF04227.12 KNZ78557.1 - 4.1e-102 341.5 3.0 3.9e-73 246.4 0.9 2.2 1 1 1 2 2 2 2 Indigoidine synthase A like protein PfkB PF00294.24 KNZ78557.1 - 2e-11 43.8 0.1 1.1e-09 38.1 0.0 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase MoaE PF02391.17 KNZ78558.1 - 9.2e-41 138.7 0.0 1.1e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 MoaE protein ICE2 PF08426.10 KNZ78559.1 - 3.5e-31 108.7 34.0 1e-17 64.4 18.4 2.9 1 1 1 2 2 2 2 ICE2 SNAP PF14938.6 KNZ78560.1 - 1e-106 356.5 17.2 1.2e-106 356.3 17.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 KNZ78560.1 - 0.00055 19.8 6.3 0.16 12.1 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Spatacsin_C PF14649.6 KNZ78560.1 - 0.061 12.4 5.0 0.44 9.6 5.0 2.1 1 1 0 1 1 1 0 Spatacsin C-terminus TC1 PF15063.6 KNZ78560.1 - 0.13 12.1 1.5 0.4 10.6 0.2 2.4 2 0 0 2 2 2 0 Thyroid cancer protein 1 TPR_6 PF13174.6 KNZ78560.1 - 0.32 11.7 13.2 18 6.2 0.2 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 KNZ78560.1 - 0.67 10.9 11.3 8 7.7 0.0 6.4 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_11 PF13414.6 KNZ78560.1 - 2 8.2 7.8 5.3 6.8 0.1 4.6 5 0 0 5 5 5 0 TPR repeat TPR_16 PF13432.6 KNZ78560.1 - 7.1 7.4 10.8 1 10.1 0.4 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ78560.1 - 8 6.8 18.4 1.1 9.6 5.9 4.2 2 1 3 5 5 5 0 Tetratricopeptide repeat Prenyltransf PF01255.19 KNZ78561.1 - 0.1 12.1 0.3 9.5 5.7 0.0 2.5 3 0 0 3 3 3 0 Putative undecaprenyl diphosphate synthase DUF2235 PF09994.9 KNZ78562.1 - 7.1e-60 202.8 0.0 8e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_61 PF03443.14 KNZ78563.1 - 2e-56 191.2 0.0 3.1e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3923 PF13061.6 KNZ78563.1 - 0.022 14.9 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3923) Sigma70_r4 PF04545.16 KNZ78563.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TRAP_alpha PF03896.16 KNZ78564.1 - 0.015 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Herpes_gE PF02480.16 KNZ78564.1 - 0.093 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MGC-24 PF05283.11 KNZ78564.1 - 2.9 8.3 5.5 1.3 9.5 1.9 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Phage_holin_8 PF16931.5 KNZ78565.1 - 0.35 10.8 6.2 0.07 13.1 2.4 1.7 2 0 0 2 2 2 0 Putative phage holin AF-4 PF05110.13 KNZ78565.1 - 1.9 6.5 4.3 2.4 6.2 4.3 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_hydro_61 PF03443.14 KNZ78566.1 - 1.6e-43 149.1 0.1 1.9e-43 148.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_N PF08240.12 KNZ78567.1 - 7.8e-17 61.1 0.7 1.3e-16 60.4 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ78567.1 - 4.1e-13 49.4 0.1 7.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KNZ78567.1 - 0.00079 18.8 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KNZ78567.1 - 0.0025 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Abhydrolase_6 PF12697.7 KNZ78568.1 - 5.4e-07 30.4 0.0 6.4e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ78568.1 - 0.00051 19.8 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ78569.1 - 7.7e-08 33.2 0.0 9.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MARVEL PF01284.23 KNZ78572.1 - 2.4 8.2 18.0 11 6.0 12.5 2.4 2 1 0 2 2 2 0 Membrane-associating domain DUF4191 PF13829.6 KNZ78573.1 - 0.049 13.0 0.5 0.095 12.0 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) p450 PF00067.22 KNZ78574.1 - 1.5e-57 195.4 0.1 2.8e-55 187.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF4875 PF16175.5 KNZ78574.1 - 0.2 11.8 0.0 0.52 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) TPR_2 PF07719.17 KNZ78575.1 - 2.7e-15 55.2 22.8 0.011 15.8 0.1 11.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ78575.1 - 5.4e-14 52.5 25.2 0.0033 17.9 0.1 8.3 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ78575.1 - 1.1e-11 45.2 18.1 0.054 14.2 0.6 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ78575.1 - 1.6e-11 44.3 21.3 1.9e-06 28.1 0.4 8.4 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ78575.1 - 3.3e-11 43.0 21.6 0.032 15.0 0.2 10.2 8 2 3 11 11 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ78575.1 - 1.6e-10 40.3 15.1 0.59 10.5 0.0 10.5 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ78575.1 - 6.2e-10 38.5 13.8 0.074 12.9 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ78575.1 - 1.5e-07 31.0 7.9 0.0013 18.4 0.2 5.9 7 0 0 7 7 6 2 TPR repeat TPR_17 PF13431.6 KNZ78575.1 - 3.7e-07 30.1 0.1 0.14 12.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ78575.1 - 8.5e-06 25.4 14.2 1.4 9.1 0.0 8.0 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ78575.1 - 4.6e-05 23.8 14.5 5.4 7.9 0.0 8.7 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_20 PF14561.6 KNZ78575.1 - 0.0018 18.5 9.5 0.19 12.1 0.2 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ78575.1 - 0.0048 17.1 17.4 1.6 9.0 0.0 6.2 5 2 2 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 KNZ78575.1 - 0.024 15.1 5.5 5 7.6 0.1 4.0 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation ChAPs PF09295.10 KNZ78575.1 - 0.037 13.0 0.4 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 KNZ78575.1 - 0.041 14.0 0.1 0.041 14.0 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat UPF0253 PF06786.12 KNZ78575.1 - 0.12 12.7 0.4 2 8.8 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0253) Vps39_1 PF10366.9 KNZ78575.1 - 0.13 12.5 0.5 6.3 7.1 0.1 3.3 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 TPR_10 PF13374.6 KNZ78575.1 - 0.16 11.9 11.1 3 7.8 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC5 PF12862.7 KNZ78575.1 - 0.16 12.0 0.8 61 3.8 0.0 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 STAT6_C PF14596.6 KNZ78576.1 - 0.11 12.5 0.2 0.12 12.4 0.2 1.1 1 0 0 1 1 1 0 STAT6 C-terminal ABC_tran PF00005.27 KNZ78578.1 - 1.1e-50 171.7 0.0 2.2e-31 109.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KNZ78578.1 - 5.8e-30 104.9 22.5 4.8e-14 52.7 3.6 3.7 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 KNZ78578.1 - 1.6e-08 34.3 0.0 0.00043 19.8 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KNZ78578.1 - 7.5e-08 32.5 1.5 0.29 10.9 0.1 4.4 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KNZ78578.1 - 2.4e-06 27.2 0.3 0.037 13.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KNZ78578.1 - 4.3e-06 27.4 0.1 0.0015 19.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KNZ78578.1 - 1.6e-05 24.6 0.0 0.055 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KNZ78578.1 - 2.9e-05 23.3 0.3 0.054 12.5 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KNZ78578.1 - 9.1e-05 22.9 0.9 0.37 11.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.22 KNZ78578.1 - 0.018 14.2 0.1 0.12 11.5 0.1 2.0 1 1 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 KNZ78578.1 - 0.023 14.8 0.2 0.051 13.7 0.2 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 KNZ78578.1 - 0.027 14.5 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 KNZ78578.1 - 0.03 14.6 0.2 32 4.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 KNZ78578.1 - 0.032 14.1 0.0 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_ATPase PF09818.9 KNZ78578.1 - 0.034 13.0 0.2 0.58 8.9 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RseC_MucC PF04246.12 KNZ78578.1 - 0.035 14.0 0.0 0.035 14.0 0.0 2.7 2 0 0 2 2 1 0 Positive regulator of sigma(E), RseC/MucC AAA_7 PF12775.7 KNZ78578.1 - 0.039 13.5 0.1 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KNZ78578.1 - 0.042 13.2 0.0 6 6.1 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KNZ78578.1 - 0.17 11.5 0.0 7.9 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 KNZ78578.1 - 0.53 10.7 2.2 1.3e+02 3.0 0.1 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KNZ78578.1 - 0.64 9.9 2.2 5.4 6.9 0.0 2.9 3 0 0 3 3 3 0 NACHT domain FmdA_AmdA PF03069.15 KNZ78579.1 - 8.4e-93 311.2 0.0 1e-92 310.9 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family WD40 PF00400.32 KNZ78580.1 - 3.1e-139 448.7 70.0 2.7e-10 40.6 0.3 15.0 14 0 0 14 14 14 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78580.1 - 4.4e-35 119.9 12.7 0.02 15.2 0.0 13.4 1 1 13 14 14 14 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ78580.1 - 2e-27 96.3 0.7 1.2e-05 25.3 0.0 6.4 1 1 6 7 7 7 7 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 KNZ78580.1 - 2.4e-16 60.1 19.8 3.5e-05 23.5 0.8 6.0 1 1 3 4 4 4 4 PQQ-like domain Frtz PF11768.8 KNZ78580.1 - 1.2e-15 56.9 1.1 0.18 10.1 0.0 9.3 1 1 11 12 12 12 8 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KNZ78580.1 - 1.6e-14 53.7 25.9 0.067 12.1 0.0 12.5 1 1 13 14 14 14 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KNZ78580.1 - 3.3e-14 52.4 3.8 3.1 7.9 0.0 11.4 13 0 0 13 13 13 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 KNZ78580.1 - 3e-13 49.8 6.5 0.065 12.6 0.0 7.5 2 2 3 8 8 8 4 WD40-like domain NACHT PF05729.12 KNZ78580.1 - 3.3e-10 40.1 0.0 8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ret2_MD PF18528.1 KNZ78580.1 - 7.5e-07 29.4 0.4 2 8.9 0.0 7.7 4 3 5 9 9 9 1 RNA editing 3' terminal uridylyl transferase 2 middle domain AAA_16 PF13191.6 KNZ78580.1 - 8.2e-06 26.3 0.3 2.1e-05 25.0 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain PQQ PF01011.21 KNZ78580.1 - 2.1e-05 24.2 0.0 2.5e+02 1.9 0.0 8.8 11 0 0 11 11 10 0 PQQ enzyme repeat APS_kinase PF01583.20 KNZ78580.1 - 0.00066 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.6 KNZ78580.1 - 0.0049 16.6 0.0 0.11 12.3 0.0 3.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ78580.1 - 0.0055 17.0 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ78580.1 - 0.017 15.6 0.0 0.078 13.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KNZ78580.1 - 0.035 13.3 0.0 0.078 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KNZ78580.1 - 0.07 13.5 0.0 0.29 11.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KNZ78580.1 - 0.088 13.4 0.0 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ78580.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 KNZ78580.1 - 0.17 11.6 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase ATPase_2 PF01637.18 KNZ78580.1 - 0.18 11.7 0.1 1.1 9.2 0.0 2.2 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea zf-RVT PF13966.6 KNZ78584.1 - 0.0017 19.0 0.1 0.0058 17.3 0.1 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FliG_C PF01706.16 KNZ78586.1 - 0.046 13.9 0.5 1.5 9.0 0.0 2.8 1 1 2 3 3 3 0 FliG C-terminal domain BEX PF04538.12 KNZ78586.1 - 0.071 13.7 0.8 0.071 13.7 0.8 1.6 2 0 0 2 2 2 0 Brain expressed X-linked like family DAO PF01266.24 KNZ78587.1 - 2.8e-32 112.7 0.1 3.4e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ78587.1 - 0.0023 18.1 0.1 0.0061 16.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KNZ78587.1 - 0.0079 15.5 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ78587.1 - 0.018 14.3 0.1 0.038 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 KNZ78587.1 - 0.038 13.2 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3246 PF11596.8 KNZ78588.1 - 0.06 12.8 0.6 0.16 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf-C2H2 PF00096.26 KNZ78588.1 - 0.67 10.5 4.8 1.6 9.4 4.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type TMEMspv1-c74-12 PF11044.8 KNZ78589.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Putative_PNPOx PF01243.20 KNZ78591.1 - 0.00017 21.7 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase p450 PF00067.22 KNZ78594.1 - 9.5e-60 202.6 0.0 1e-49 169.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF4939 PF16297.5 KNZ78596.1 - 0.0043 16.9 0.0 0.0065 16.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 KNZ78596.1 - 0.079 13.2 0.1 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 Retrotransposon gag protein Lip_prot_lig_C PF10437.9 KNZ78597.1 - 6.2e-05 22.9 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 KNZ78597.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MWFE PF15879.5 KNZ78598.1 - 1.9e-23 82.3 0.1 2.4e-23 82.0 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ORC6 PF05460.13 KNZ78600.1 - 0.12 11.7 0.1 0.12 11.6 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Terpene_synth_C PF03936.16 KNZ78601.1 - 1.3e-08 34.6 0.4 1.9e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TB2_DP1_HVA22 PF03134.19 KNZ78602.1 - 7.3e-11 41.8 0.0 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.17 KNZ78603.1 - 3.3e-68 228.0 7.0 3.7e-68 227.9 7.0 1.0 1 0 0 1 1 1 1 G10 protein Na_H_Exchanger PF00999.21 KNZ78604.1 - 3e-38 131.6 42.9 4.5e-37 127.7 42.9 2.1 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Cys_Met_Meta_PP PF01053.20 KNZ78605.1 - 3.3e-133 443.9 0.0 3.8e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KNZ78605.1 - 9e-09 35.0 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KNZ78605.1 - 2.1e-08 33.9 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KNZ78605.1 - 2.5e-06 26.7 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNZ78605.1 - 4.7e-05 22.8 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KNZ78605.1 - 0.0024 16.5 0.2 0.0054 15.3 0.1 1.6 2 0 0 2 2 2 1 Methionine gamma-lyase Asparaginase_C PF17763.1 KNZ78605.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 KNZ78605.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Acyltransferase PF01553.21 KNZ78607.1 - 4.1e-28 97.7 0.0 6.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase GDPD PF03009.17 KNZ78608.1 - 2.3e-25 89.8 0.0 2.1e-24 86.7 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family THB PF18362.1 KNZ78608.1 - 0.0048 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Tri-helix bundle domain zf-CCHC PF00098.23 KNZ78613.1 - 0.08 13.0 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle RT_RNaseH PF17917.1 KNZ78614.1 - 1.2e-09 38.4 0.0 2.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78614.1 - 1.1e-06 28.6 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 KNZ78616.1 - 2.8e-28 97.5 0.0 2.3e-16 59.4 0.0 5.1 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KNZ78616.1 - 2.3e-05 24.4 0.0 5.7e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 KNZ78616.1 - 0.0018 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 KNZ78616.1 - 0.022 14.3 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ78616.1 - 0.031 14.4 0.0 0.61 10.2 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif RasGAP PF00616.19 KNZ78617.1 - 3.6e-15 56.2 0.1 1.4e-09 38.0 0.0 3.1 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KNZ78617.1 - 2.5e-06 27.7 0.2 9e-06 25.9 0.2 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.6 KNZ78617.1 - 0.035 14.0 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Cell morphogenesis C-terminal NYD-SP28_assoc PF14775.6 KNZ78618.1 - 2.8 8.1 10.1 0.98 9.6 0.4 3.7 3 0 0 3 3 3 0 Sperm tail C-terminal domain RGS PF00615.19 KNZ78619.1 - 6e-06 26.5 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain Tankyrase_bdg_C PF15327.6 KNZ78619.1 - 0.0072 16.8 0.2 0.012 16.1 0.2 1.3 1 0 0 1 1 1 1 Tankyrase binding protein C terminal domain DUF4131 PF13567.6 KNZ78619.1 - 0.037 13.7 0.2 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ATG22 PF11700.8 KNZ78621.1 - 5e-86 289.2 12.6 5.6e-86 289.1 12.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KNZ78621.1 - 1.7e-08 33.8 25.4 2.8e-06 26.5 11.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily SHOCT PF09851.9 KNZ78621.1 - 0.15 11.8 0.6 0.34 10.7 0.6 1.5 1 0 0 1 1 1 0 Short C-terminal domain DUF2721 PF11026.8 KNZ78621.1 - 0.16 11.8 0.9 0.45 10.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Band_7 PF01145.25 KNZ78622.1 - 4.3e-17 62.7 9.8 2e-11 44.2 1.5 2.4 2 1 1 3 3 3 2 SPFH domain / Band 7 family ZnuA PF01297.17 KNZ78622.1 - 0.011 15.1 0.1 0.018 14.5 0.1 1.4 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic Band_7_1 PF13421.6 KNZ78622.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family SBP_bac_5 PF00496.22 KNZ78622.1 - 0.054 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle EVE PF01878.18 KNZ78623.1 - 5.6e-37 127.0 0.6 1.1e-36 126.0 0.0 1.8 2 0 0 2 2 2 1 EVE domain PBP1_TM PF14812.6 KNZ78623.1 - 0.15 12.4 8.7 0.38 11.1 8.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 KNZ78623.1 - 5.9 5.0 8.4 7.4 4.7 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Arrestin_N PF00339.29 KNZ78624.1 - 3.8e-08 33.5 0.0 6.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain GRAM PF02893.20 KNZ78625.1 - 8.8e-06 25.6 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 KNZ78625.1 - 0.0043 17.2 0.0 0.015 15.5 0.0 1.9 3 0 0 3 3 3 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 KNZ78625.1 - 0.094 13.1 0.3 0.19 12.1 0.1 1.7 2 1 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Pkinase PF00069.25 KNZ78629.1 - 1e-40 139.8 0.0 7.5e-23 81.2 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78629.1 - 2.3e-12 46.8 0.0 1.2e-08 34.6 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ78629.1 - 0.00028 20.9 0.0 0.00061 19.8 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KNZ78629.1 - 0.036 13.7 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KNZ78629.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KNZ78629.1 - 0.2 11.0 0.0 1.9 7.8 0.0 2.0 2 0 0 2 2 2 0 Kinase-like UCH PF00443.29 KNZ78630.1 - 1.1e-33 116.8 0.0 1.9e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ78630.1 - 1.8e-06 27.8 0.0 4.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1992 PF09350.10 KNZ78632.1 - 9.5e-22 76.9 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Glyco_hydro_61 PF03443.14 KNZ78633.1 - 2.3e-62 210.6 0.2 2.7e-62 210.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_zinc_N PF00107.26 KNZ78634.1 - 3.1e-12 46.6 0.0 4.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ78634.1 - 3.1e-08 33.5 0.0 5.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KNZ78634.1 - 0.015 16.3 0.0 0.024 15.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ78634.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Pro_isomerase PF00160.21 KNZ78635.1 - 1.9e-38 132.2 0.0 2.8e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KNZ78635.1 - 5.6e-16 58.1 0.0 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.31 KNZ78636.1 - 6.7e-14 52.1 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Stc1 PF12898.7 KNZ78636.1 - 0.018 15.6 0.0 0.08 13.5 0.0 2.0 1 1 0 1 1 1 0 Stc1 domain Aldedh PF00171.22 KNZ78637.1 - 5e-102 341.8 0.0 6.2e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_12 PF01670.16 KNZ78638.1 - 4.7e-33 115.0 8.1 6e-33 114.6 8.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF4470 PF14737.6 KNZ78639.1 - 4.6e-23 81.2 0.0 1.3e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 KNZ78639.1 - 1.4e-10 41.0 10.9 1.4e-10 41.0 10.9 2.3 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KNZ78639.1 - 0.13 12.6 7.6 0.4 11.0 7.6 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 KNZ78639.1 - 0.24 11.5 4.0 0.66 10.1 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 KNZ78639.1 - 0.29 11.1 7.6 0.63 10.0 7.6 1.6 1 0 0 1 1 1 0 HIT zinc finger Cullin PF00888.22 KNZ78640.1 - 1.9e-179 598.3 20.7 1.9e-179 598.3 20.7 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KNZ78640.1 - 1.5e-26 92.2 3.1 1.5e-26 92.2 3.1 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Rrf2 PF02082.20 KNZ78640.1 - 0.054 13.8 1.2 0.16 12.3 0.3 2.2 2 0 0 2 2 2 0 Transcriptional regulator MarR_2 PF12802.7 KNZ78640.1 - 0.06 13.2 0.1 5.2 7.0 0.0 2.9 3 0 0 3 3 3 0 MarR family Phage_rep_O PF04492.13 KNZ78640.1 - 0.12 13.0 1.0 0.26 11.9 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage replication protein O FACT-Spt16_Nlob PF14826.6 KNZ78640.1 - 2.2 8.0 10.2 0.2 11.5 0.2 3.1 3 1 0 3 3 3 0 FACT complex subunit SPT16 N-terminal lobe domain WD40 PF00400.32 KNZ78641.1 - 1.1e-29 102.0 5.8 4.8e-05 24.0 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78641.1 - 2.9e-15 56.3 0.1 7.8e-05 22.9 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ78641.1 - 7.4e-05 22.2 0.1 0.084 12.2 0.0 2.8 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 KNZ78641.1 - 0.00017 21.6 0.0 0.055 13.4 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 KNZ78641.1 - 0.0013 19.2 3.5 1.2 9.7 0.0 4.8 4 1 0 4 4 4 1 PQQ-like domain Cytochrom_D1 PF02239.16 KNZ78641.1 - 0.0027 16.3 0.0 0.19 10.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Me-amine-dh_H PF06433.11 KNZ78641.1 - 0.0028 16.6 0.0 0.0089 14.9 0.0 1.8 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 KNZ78641.1 - 0.0081 15.2 0.1 12 4.8 0.0 3.2 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KNZ78641.1 - 0.0083 14.5 0.0 0.14 10.4 0.0 2.4 2 1 2 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 KNZ78641.1 - 0.012 15.2 0.6 0.92 9.0 0.1 2.9 2 1 1 3 3 3 0 PQQ-like domain Arb1 PF09692.10 KNZ78643.1 - 1.5e-08 34.3 0.0 1.3e-07 31.1 0.0 2.4 4 1 1 5 5 5 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 zf-CCHC PF00098.23 KNZ78651.1 - 0.11 12.7 0.8 0.11 12.7 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ78651.1 - 0.8 9.5 4.2 1.4 8.7 4.2 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC PF00098.23 KNZ78652.1 - 0.11 12.7 0.8 0.11 12.7 0.8 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ78652.1 - 0.8 9.5 4.2 1.4 8.7 4.2 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Helitron_like_N PF14214.6 KNZ78653.1 - 8.5e-64 215.3 0.1 1.2e-63 214.8 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ78653.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) ArsC PF03960.15 KNZ78659.1 - 0.15 12.1 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 ArsC family Glyco_hydro_16 PF00722.21 KNZ78660.1 - 4.8e-39 133.6 6.7 7e-39 133.1 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RRM_1 PF00076.22 KNZ78661.1 - 3e-22 78.2 0.0 1.7e-10 40.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNZ78661.1 - 0.00018 21.1 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 KNZ78661.1 - 0.13 12.4 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain Hydrophobin PF01185.18 KNZ78662.1 - 4.6e-18 65.6 11.1 6.1e-18 65.2 11.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin CLIP_SPH_mas PF18398.1 KNZ78662.1 - 0.023 15.1 6.6 0.43 11.0 0.6 2.4 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade KASH PF10541.9 KNZ78662.1 - 0.27 11.5 2.4 1.2 9.5 0.2 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain RNA_pol_L_2 PF13656.6 KNZ78663.1 - 2.5e-27 94.5 0.0 3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KNZ78663.1 - 9.6e-07 28.1 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Abhydrolase_1 PF00561.20 KNZ78665.1 - 1.7e-18 67.2 0.0 5.4e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ78665.1 - 3e-15 57.4 4.5 2.3e-14 54.6 4.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ78665.1 - 6.4e-08 32.2 0.0 1.9e-06 27.3 0.1 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 KNZ78665.1 - 0.0065 16.1 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 KNZ78665.1 - 0.0075 15.0 0.0 0.64 8.7 0.0 2.1 2 0 0 2 2 2 2 Ndr family Abhydrolase_8 PF06259.12 KNZ78665.1 - 0.056 13.1 0.4 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Peptidase_S9 PF00326.21 KNZ78665.1 - 0.06 12.8 0.0 1.4 8.4 0.0 2.5 2 1 0 2 2 2 0 Prolyl oligopeptidase family RA PF00788.23 KNZ78666.1 - 7.7e-11 42.5 0.0 3.7e-08 33.9 0.0 3.2 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 KNZ78666.1 - 8.8e-06 25.2 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ78666.1 - 0.00097 18.9 0.5 0.008 16.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain Par3_HAL_N_term PF12053.8 KNZ78666.1 - 0.09 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins DSPc PF00782.20 KNZ78667.1 - 1e-26 93.3 0.0 1.5e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KNZ78667.1 - 0.0013 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3151 PF11349.8 KNZ78667.1 - 0.07 13.2 0.0 0.75 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3151) DDE_1 PF03184.19 KNZ78669.1 - 9.2e-14 51.5 0.6 1.3e-13 51.0 0.3 1.3 2 0 0 2 2 2 1 DDE superfamily endonuclease Glyco_hydro_25 PF01183.20 KNZ78670.1 - 8.5e-51 172.7 0.3 9.6e-51 172.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF2855 PF11017.8 KNZ78671.1 - 1.1e-101 340.9 0.2 1.3e-101 340.7 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) PDEase_I PF00233.19 KNZ78672.1 - 8.5e-52 176.2 0.0 2.1e-51 175.0 0.0 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 KNZ78672.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 HD domain Helitron_like_N PF14214.6 KNZ78673.1 - 7.8e-05 23.0 0.5 0.00012 22.3 0.5 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Chromo PF00385.24 KNZ78674.1 - 2.8e-17 62.4 0.0 3.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ78674.1 - 0.058 13.6 0.1 0.085 13.0 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Sec23_trunk PF04811.15 KNZ78675.1 - 9e-44 149.9 0.0 1.6e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KNZ78675.1 - 2.1e-21 75.7 0.2 5.5e-21 74.3 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KNZ78675.1 - 3.5e-15 55.8 2.3 8.9e-15 54.5 2.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 KNZ78675.1 - 8.8e-13 48.8 0.3 1.8e-12 47.8 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 KNZ78675.1 - 2.7e-07 30.4 0.0 5.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Mcp5_PH PF12814.7 KNZ78676.1 - 3.4e-44 149.8 0.0 8.8e-44 148.5 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KNZ78676.1 - 1.4e-05 25.5 0.0 3.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 KNZ78676.1 - 0.033 12.1 9.0 0.054 11.5 9.0 1.2 1 0 0 1 1 1 0 Prominin RCC1 PF00415.18 KNZ78676.1 - 0.04 14.5 0.0 0.15 12.7 0.0 2.0 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Lyase_8_N PF08124.11 KNZ78676.1 - 0.31 9.9 2.8 0.73 8.7 2.8 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain LMBR1 PF04791.16 KNZ78676.1 - 1 8.2 7.1 1.8 7.4 7.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PIG-S PF10510.9 KNZ78676.1 - 1.2 7.8 5.0 2.9 6.6 5.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein HAP1_N PF04849.13 KNZ78676.1 - 2.1 7.5 29.9 0.33 10.1 2.6 3.2 3 0 0 3 3 3 0 HAP1 N-terminal conserved region HeLo PF14479.6 KNZ78676.1 - 2.6 7.8 12.1 1.9 8.2 8.4 2.4 2 0 0 2 2 2 0 Prion-inhibition and propagation Aspzincin_M35 PF14521.6 KNZ78677.1 - 1.8e-20 74.0 3.3 1.9e-20 73.9 1.0 2.1 1 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KNZ78677.1 - 0.0041 16.7 0.8 0.2 11.2 0.0 2.3 2 0 0 2 2 2 2 Putative peptidase family 2OG-FeII_Oxy_3 PF13640.6 KNZ78678.1 - 7.4e-09 36.4 0.1 1.2e-08 35.7 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Keratin_assoc PF09775.9 KNZ78678.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 2OG-FeII_Oxy_3 PF13640.6 KNZ78679.1 - 2.3e-09 38.0 0.0 4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Keratin_assoc PF09775.9 KNZ78679.1 - 0.021 14.5 0.4 0.039 13.6 0.4 1.4 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 2OG-FeII_Oxy_3 PF13640.6 KNZ78680.1 - 3.9e-09 37.3 0.1 7.6e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 KNZ78680.1 - 0.045 14.4 0.0 0.093 13.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 KNZ78681.1 - 7.7e-78 262.3 0.0 9.1e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SWIRM PF04433.17 KNZ78682.1 - 4.2e-32 110.3 0.0 5.6e-31 106.7 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 KNZ78682.1 - 5.6e-19 67.9 6.7 5.6e-19 67.9 6.7 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 KNZ78682.1 - 3e-12 46.5 0.1 6.1e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ78682.1 - 5.3e-10 39.4 0.0 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1192 PF06698.11 KNZ78683.1 - 0.16 12.1 0.9 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ArgJ PF01960.18 KNZ78684.1 - 1.7e-122 408.8 0.4 8.7e-97 324.2 1.7 2.0 2 0 0 2 2 2 2 ArgJ family DEAD PF00270.29 KNZ78685.1 - 1.2e-45 155.4 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ78685.1 - 7.6e-31 106.7 0.1 2.5e-30 105.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78685.1 - 3.5e-06 27.1 0.0 6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNZ78685.1 - 0.095 13.0 1.1 0.86 9.9 1.1 2.5 1 1 0 1 1 1 0 AAA domain SRR1 PF07985.12 KNZ78686.1 - 0.033 14.2 0.0 4.9 7.3 0.0 2.3 2 0 0 2 2 2 0 SRR1 RRM_1 PF00076.22 KNZ78688.1 - 3.2e-49 164.6 0.0 6.5e-16 57.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 KNZ78688.1 - 0.0038 17.3 0.0 0.28 11.3 0.0 3.3 3 1 0 3 3 3 1 Limkain b1 DUF3343 PF11823.8 KNZ78688.1 - 0.0039 16.6 0.0 0.028 13.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3343) RRM_5 PF13893.6 KNZ78688.1 - 0.017 14.7 0.0 2.8 7.5 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) gpW PF02831.15 KNZ78688.1 - 0.041 13.8 0.2 0.44 10.5 0.0 2.5 3 0 0 3 3 3 0 gpW Presenilin PF01080.17 KNZ78688.1 - 1.8 7.3 5.4 2.4 6.8 5.4 1.1 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 KNZ78688.1 - 3.8 6.3 14.0 5.2 5.8 14.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Methyltransf_2 PF00891.18 KNZ78689.1 - 2e-25 89.4 0.0 1.9e-23 82.9 0.0 2.5 3 0 0 3 3 3 1 O-methyltransferase domain Tetraspanin PF00335.20 KNZ78689.1 - 6.3e-10 39.1 8.5 1e-09 38.5 8.5 1.3 1 0 0 1 1 1 1 Tetraspanin family Dimerisation PF08100.11 KNZ78689.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain FTR1 PF03239.14 KNZ78689.1 - 0.034 13.3 0.4 0.059 12.5 0.4 1.3 1 0 0 1 1 1 0 Iron permease FTR1 family RPA_C PF08784.11 KNZ78689.1 - 0.096 13.4 0.0 0.24 12.1 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal DUF2207 PF09972.9 KNZ78689.1 - 0.18 10.6 0.3 0.41 9.4 0.3 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SPC12 PF06645.13 KNZ78689.1 - 0.28 11.3 4.9 0.27 11.4 2.2 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) HsbA PF12296.8 KNZ78690.1 - 2.2e-11 44.2 1.5 2.2e-11 44.2 1.5 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A NAD_binding_9 PF13454.6 KNZ78692.1 - 2.3e-05 24.4 0.0 0.00012 22.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KNZ78692.1 - 0.00051 19.4 0.0 0.92 8.7 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase zf-MYND PF01753.18 KNZ78693.1 - 1e-05 25.5 0.9 1.9e-05 24.6 0.9 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 KNZ78693.1 - 0.031 15.4 0.7 0.12 13.6 0.1 1.9 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins DUF2256 PF10013.9 KNZ78693.1 - 0.29 11.3 1.7 0.56 10.4 1.7 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) N6-adenineMlase PF10237.9 KNZ78694.1 - 5.2e-38 130.4 0.0 6.1e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Formyl_trans_N PF00551.19 KNZ78695.1 - 2.5e-38 131.6 0.0 3e-37 128.1 0.0 1.9 1 1 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.18 KNZ78695.1 - 0.053 13.4 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Pkinase PF00069.25 KNZ78696.1 - 7.3e-60 202.6 0.0 9.1e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78696.1 - 3.9e-27 95.2 0.0 5.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ78696.1 - 6.2e-06 25.7 0.0 9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ78696.1 - 2.8e-05 23.6 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ78696.1 - 0.00026 20.7 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 KNZ78696.1 - 0.0066 16.4 0.2 0.82 9.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ78696.1 - 0.02 13.8 0.4 0.044 12.7 0.4 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Sec62 PF03839.16 KNZ78697.1 - 5.5e-53 179.7 6.2 1.6e-52 178.2 6.2 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 TPR_7 PF13176.6 KNZ78698.1 - 5.7e-05 22.9 0.3 2.9 8.1 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ78698.1 - 8.5e-05 22.8 10.9 0.89 9.9 1.4 5.0 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ78698.1 - 0.035 14.2 6.7 1.3 9.3 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3613 PF12266.8 KNZ78698.1 - 0.091 12.6 0.4 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) DUF2225 PF09986.9 KNZ78698.1 - 0.18 11.5 0.7 11 5.7 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 KNZ78698.1 - 0.66 10.5 2.5 16 6.2 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ78698.1 - 1.2 9.9 4.0 1.2 9.9 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ead_Ea22 PF13935.6 KNZ78699.1 - 0.0015 19.2 2.2 0.04 14.6 1.7 2.3 1 1 0 1 1 1 1 Ead/Ea22-like protein Macoilin PF09726.9 KNZ78699.1 - 0.0017 17.0 9.4 0.002 16.8 9.4 1.0 1 0 0 1 1 1 1 Macoilin family APG6_N PF17675.1 KNZ78699.1 - 0.0037 17.8 4.7 0.0037 17.8 4.7 2.4 2 1 0 2 2 2 1 Apg6 coiled-coil region HALZ PF02183.18 KNZ78699.1 - 0.0051 17.0 5.7 0.014 15.6 0.4 3.0 3 0 0 3 3 3 1 Homeobox associated leucine zipper CCDC92 PF14916.6 KNZ78699.1 - 0.022 14.5 0.1 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Com_YlbF PF06133.11 KNZ78699.1 - 0.078 13.6 4.7 0.88 10.2 0.3 3.0 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA Ax_dynein_light PF10211.9 KNZ78699.1 - 0.28 11.1 9.0 0.032 14.2 3.7 1.9 2 1 0 2 2 2 0 Axonemal dynein light chain DUF3772 PF12607.8 KNZ78699.1 - 0.35 10.7 9.3 0.29 10.9 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3772) betaPIX_CC PF16523.5 KNZ78699.1 - 0.52 10.2 11.4 3.4 7.6 0.2 4.0 3 1 0 4 4 4 0 betaPIX coiled coil Cep57_CLD_2 PF14197.6 KNZ78699.1 - 0.78 9.9 14.1 1.8 8.7 0.9 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF1640 PF07798.11 KNZ78699.1 - 1.7 8.7 6.4 0.14 12.2 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) SHE3 PF17078.5 KNZ78699.1 - 8.1 6.1 10.2 3.8 7.2 5.6 2.3 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 Rad52_Rad22 PF04098.15 KNZ78700.1 - 5.9e-58 195.1 0.9 7.6e-58 194.8 0.0 1.6 2 0 0 2 2 2 1 Rad52/22 family double-strand break repair protein HLH PF00010.26 KNZ78702.1 - 7e-08 32.3 1.5 1.5e-07 31.3 0.4 2.2 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain PKcGMP_CC PF16808.5 KNZ78702.1 - 0.0019 18.0 1.6 0.0033 17.2 1.6 1.4 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Sec23_trunk PF04811.15 KNZ78703.1 - 2.4e-72 243.4 0.0 8.1e-72 241.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KNZ78703.1 - 1.8e-22 79.1 0.0 5.3e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KNZ78703.1 - 2.1e-18 66.9 0.0 5.4e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KNZ78703.1 - 3.5e-16 58.9 7.3 7.8e-16 57.8 7.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KNZ78703.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 KNZ78703.1 - 1.8e-06 27.9 0.4 1.8e-06 27.9 0.4 2.2 2 0 0 2 2 2 1 WW domain Vps36-NZF-N PF16988.5 KNZ78703.1 - 0.026 13.9 0.6 0.05 13.0 0.6 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CAP PF00188.26 KNZ78704.1 - 2.3e-24 86.6 0.2 2.9e-24 86.3 0.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4513 PF14983.6 KNZ78705.1 - 0.098 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) ELYS PF13934.6 KNZ78706.1 - 8.8e-35 120.7 0.4 1.9e-34 119.6 0.4 1.6 1 0 0 1 1 1 1 Nuclear pore complex assembly ATP-synt_10 PF05176.14 KNZ78707.1 - 5.5e-15 55.3 0.1 8e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 ATP10 protein Histone PF00125.24 KNZ78708.1 - 6.8e-17 62.1 0.0 8.4e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KNZ78708.1 - 1.3e-16 60.0 0.5 2.4e-16 59.2 0.5 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KNZ78708.1 - 2.9e-06 27.5 0.0 4.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_Helicase PF02689.14 KNZ78709.1 - 0.00012 20.2 0.1 0.00012 20.2 0.1 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ78709.1 - 0.06 13.2 0.1 0.11 12.3 0.1 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain MFS_1 PF07690.16 KNZ78710.1 - 1.1e-40 139.7 45.0 1.6e-40 139.1 45.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ78710.1 - 1.2e-11 44.1 5.7 1.2e-11 44.1 5.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 KNZ78710.1 - 0.0016 17.0 3.9 0.0016 17.0 3.9 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector DUF4022 PF13214.6 KNZ78710.1 - 0.13 12.6 3.5 0.17 12.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4022) DUF563 PF04577.14 KNZ78711.1 - 5.6e-11 43.0 0.1 1.5e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) NAM-associated PF14303.6 KNZ78712.1 - 0.38 11.4 1.6 0.69 10.6 1.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Sugar_tr PF00083.24 KNZ78716.1 - 2.5e-98 329.9 14.7 3.2e-98 329.5 14.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ78716.1 - 1.6e-18 66.8 30.4 2e-13 50.0 11.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNZ78716.1 - 0.0021 16.5 3.3 0.005 15.3 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 KNZ78716.1 - 0.32 11.5 4.3 0.12 13.0 0.8 2.2 2 0 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 KNZ78718.1 - 2.9e-100 336.3 21.0 3.5e-100 336.0 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ78718.1 - 6.5e-20 71.3 34.7 8.6e-15 54.5 10.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNZ78718.1 - 0.0018 16.8 1.1 0.0018 16.8 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 KNZ78719.1 - 1.7e-79 267.5 11.1 2.3e-79 267.0 11.1 1.1 1 0 0 1 1 1 1 POT family Phage_holin_3_6 PF07332.11 KNZ78719.1 - 6.7 6.8 18.0 0.94 9.5 2.2 3.6 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DDE_1 PF03184.19 KNZ78720.1 - 8.9e-18 64.5 0.2 1.3e-17 64.0 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PTR2 PF00854.21 KNZ78721.1 - 9.3e-79 265.1 10.1 1.2e-78 264.7 10.1 1.1 1 0 0 1 1 1 1 POT family Phage_holin_3_6 PF07332.11 KNZ78721.1 - 6.7 6.8 13.7 8.6 6.4 0.4 3.7 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III Methyltransf_11 PF08241.12 KNZ78722.1 - 6.3e-19 68.4 0.0 1.2e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ78722.1 - 3.2e-18 66.2 0.0 1.1e-17 64.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ78722.1 - 6e-12 45.6 0.0 9.3e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ78722.1 - 1e-11 45.4 0.0 2.4e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ78722.1 - 2.5e-05 23.7 0.0 8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KNZ78722.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ78722.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KNZ78722.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 KNZ78722.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 KNZ78722.1 - 0.17 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DUF2298 PF10060.9 KNZ78723.1 - 0.077 11.7 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) MatE PF01554.18 KNZ78724.1 - 3.5e-41 140.6 23.7 3.7e-21 75.4 8.3 2.3 2 0 0 2 2 2 2 MatE UPF0242 PF06785.11 KNZ78724.1 - 0.12 12.5 0.5 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RT_RNaseH PF17917.1 KNZ78726.1 - 2e-08 34.5 0.0 5.4e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78726.1 - 8.8e-05 22.5 0.0 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Oxidoreduct_C PF16490.5 KNZ78728.1 - 0.034 13.9 0.2 0.045 13.5 0.2 1.1 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Raftlin PF15250.6 KNZ78728.1 - 0.066 11.9 3.8 0.073 11.8 3.8 1.0 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 KNZ78728.1 - 0.076 11.3 8.4 0.081 11.2 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 KNZ78728.1 - 0.45 9.3 6.7 0.47 9.2 6.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RP-C_C PF11800.8 KNZ78728.1 - 0.53 10.4 4.3 0.92 9.6 4.3 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region Zip PF02535.22 KNZ78728.1 - 0.53 9.4 2.9 0.53 9.4 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pes-10 PF07149.11 KNZ78728.1 - 0.54 9.3 3.0 0.72 8.8 3.0 1.1 1 0 0 1 1 1 0 Pes-10 SAPS PF04499.15 KNZ78728.1 - 1 8.1 7.2 1.1 7.9 7.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sigma70_ner PF04546.13 KNZ78728.1 - 1.1 9.1 8.7 1.5 8.6 8.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CCDC106 PF15794.5 KNZ78728.1 - 1.3 8.7 9.1 1.6 8.4 9.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CobT PF06213.12 KNZ78728.1 - 2.9 7.2 10.9 3.7 6.9 10.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3024 PF11225.8 KNZ78729.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Phosphoesterase PF04185.14 KNZ78730.1 - 5.8e-31 108.0 0.3 2.3e-30 106.0 0.2 1.9 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 KNZ78730.1 - 0.037 13.4 0.1 0.051 13.0 0.1 1.2 1 0 0 1 1 1 0 Sulfatase TAL_FSA PF00923.19 KNZ78731.1 - 1.9e-94 316.3 0.0 2.1e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase GST_N_3 PF13417.6 KNZ78732.1 - 1.9e-07 31.4 0.0 3.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ78732.1 - 1.3e-05 25.3 0.1 2.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ78732.1 - 0.00058 19.8 2.5 0.00076 19.5 0.3 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ78732.1 - 0.026 14.7 0.0 0.056 13.6 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain AhpC-TSA PF00578.21 KNZ78734.1 - 9.1e-25 87.0 0.0 1.2e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNZ78734.1 - 2.1e-14 53.4 0.0 3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin HMG14_17 PF01101.18 KNZ78734.1 - 0.0015 19.4 7.4 0.0032 18.4 7.4 1.6 1 0 0 1 1 1 1 HMG14 and HMG17 LRR_6 PF13516.6 KNZ78735.1 - 9.1e-16 56.5 19.5 0.03 14.4 0.0 8.9 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 KNZ78735.1 - 7.5e-06 26.2 22.9 0.059 13.8 1.0 5.9 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) GAT PF03127.14 KNZ78735.1 - 8.5e-05 22.8 0.3 0.00025 21.3 0.3 1.8 1 0 0 1 1 1 1 GAT domain LRR_1 PF00560.33 KNZ78735.1 - 0.00069 19.8 10.9 14 6.7 0.0 7.5 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 KNZ78735.1 - 0.017 14.9 28.6 0.38 10.5 1.1 7.1 4 2 0 5 5 5 0 Leucine rich repeat Peptidase_M14 PF00246.24 KNZ78736.1 - 4.7e-57 194.0 0.0 5.3e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase SKN1 PF03935.15 KNZ78737.1 - 5.2e-38 130.7 0.0 1.7e-32 112.5 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Esterase_phd PF10503.9 KNZ78738.1 - 4.9e-24 85.1 1.0 6.7e-24 84.6 1.0 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KNZ78738.1 - 1.8e-09 37.4 0.5 2.8e-09 36.8 0.5 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KNZ78738.1 - 0.0001 22.0 0.6 0.00021 21.0 0.5 1.7 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KNZ78738.1 - 0.056 12.1 0.0 0.09 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 KNZ78738.1 - 0.058 12.9 0.3 0.19 11.2 0.3 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.9 KNZ78739.1 - 1.6e-24 86.7 0.7 2.3e-24 86.1 0.7 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KNZ78739.1 - 4.5e-09 36.1 0.4 8.5e-09 35.2 0.4 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 KNZ78739.1 - 5.6e-07 29.4 6.3 5.6e-07 29.4 6.3 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Esterase PF00756.20 KNZ78739.1 - 3.1e-06 27.0 0.6 1.5e-05 24.8 0.6 2.0 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.12 KNZ78739.1 - 0.035 12.8 0.0 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Sporozoite_P67 PF05642.11 KNZ78739.1 - 0.54 8.3 5.1 0.7 7.9 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C54 PF03416.19 KNZ78740.1 - 3.8e-101 338.1 0.0 5.8e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 zf-CCHC PF00098.23 KNZ78741.1 - 0.12 12.5 1.4 0.2 11.8 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ78741.1 - 0.48 10.2 2.0 0.81 9.5 2.0 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger gag-asp_proteas PF13975.6 KNZ78742.1 - 2.1e-06 28.2 0.0 5e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78742.1 - 1.6e-05 25.5 0.0 3.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ78742.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 KNZ78743.1 - 3.1e-06 27.4 0.0 6.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78743.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase EFG_C PF00679.24 KNZ78745.1 - 1.2e-14 54.1 0.1 2.4e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 KNZ78745.1 - 0.00011 21.8 0.0 0.0089 15.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KNZ78745.1 - 0.032 14.6 0.3 0.08 13.3 0.3 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 RHSP PF07999.11 KNZ78745.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein Retrotran_gag_2 PF14223.6 KNZ78746.1 - 2.2e-09 37.1 0.0 2.9e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type AAA_22 PF13401.6 KNZ78747.1 - 3.9e-06 27.2 0.1 1.3e-05 25.4 0.0 1.9 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 KNZ78747.1 - 1.1e-05 24.8 0.0 2.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KNZ78747.1 - 0.00015 22.2 0.1 0.0015 19.0 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KNZ78747.1 - 0.00065 20.1 0.0 0.0017 18.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNZ78747.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KNZ78747.1 - 0.014 15.3 0.1 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KNZ78747.1 - 0.019 15.0 0.9 0.084 13.0 0.0 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KNZ78747.1 - 0.049 14.2 0.1 0.42 11.1 0.0 2.5 3 0 0 3 3 3 0 ABC transporter USP8_interact PF08941.10 KNZ78747.1 - 0.1 12.4 1.1 0.47 10.2 0.3 2.0 1 1 1 2 2 2 0 USP8 interacting Mg_chelatase PF01078.21 KNZ78747.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KNZ78748.1 - 1.2e-05 25.6 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KNZ78748.1 - 2.7e-05 23.5 0.0 6.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KNZ78748.1 - 0.00057 20.3 0.1 0.0033 17.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KNZ78748.1 - 0.0084 16.5 0.0 0.021 15.2 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNZ78748.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KNZ78748.1 - 0.049 13.7 0.1 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase RuvB_N PF05496.12 KNZ78748.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 KNZ78748.1 - 0.11 13.1 0.0 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter GTP_EFTU_D2 PF03144.25 KNZ78749.1 - 7.9e-07 29.4 1.4 1.4e-06 28.6 1.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HDV_ag PF01517.18 KNZ78750.1 - 0.12 12.2 0.0 0.21 11.3 0.0 1.3 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen zf-CCHC_6 PF15288.6 KNZ78751.1 - 0.082 12.8 1.3 0.17 11.7 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle Aldedh PF00171.22 KNZ78752.1 - 2.4e-26 92.3 2.0 1.4e-19 70.0 0.3 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Pericardin_rpt PF07054.11 KNZ78752.1 - 0.37 10.9 4.2 0.31 11.2 0.6 2.1 2 0 0 2 2 2 0 Pericardin like repeat TPR_MalT PF17874.1 KNZ78753.1 - 3e-10 40.0 0.4 0.0061 16.0 0.0 3.3 2 1 1 3 3 3 3 MalT-like TPR region TPR_12 PF13424.6 KNZ78753.1 - 2.3e-09 37.4 3.9 0.07 13.4 0.1 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ78753.1 - 9.8e-08 31.6 9.1 1.6 9.0 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.6 KNZ78753.1 - 7.9e-05 23.0 0.1 0.00032 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ78753.1 - 0.00028 21.3 1.0 0.0016 18.8 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KNZ78753.1 - 0.00046 20.0 0.1 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KNZ78753.1 - 0.00054 19.2 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KNZ78753.1 - 0.0014 19.1 0.4 0.0052 17.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPR_16 PF13432.6 KNZ78753.1 - 0.0051 17.4 4.1 1.3 9.7 0.1 4.4 4 2 1 5 5 5 1 Tetratricopeptide repeat ARPC4 PF05856.12 KNZ78753.1 - 0.027 14.1 0.0 0.091 12.4 0.0 1.9 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) TPR_14 PF13428.6 KNZ78753.1 - 0.036 14.9 1.1 71 4.6 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ78753.1 - 0.08 12.8 0.4 45 4.1 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.22 KNZ78754.1 - 1.7e-08 33.4 0.1 2.6e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_22 PF13401.6 KNZ78754.1 - 2.8e-06 27.7 0.0 4.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ78754.1 - 2.3e-05 24.8 0.1 0.00017 22.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 KNZ78754.1 - 7.4e-05 22.5 0.0 9.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 KNZ78754.1 - 0.00017 20.9 0.0 0.00038 19.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 KNZ78754.1 - 0.0073 16.7 0.0 0.015 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 KNZ78754.1 - 0.0074 16.4 0.1 0.013 15.5 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ78754.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 KNZ78754.1 - 0.068 13.7 0.2 0.24 11.9 0.1 1.9 1 1 1 2 2 2 0 ABC transporter DUF815 PF05673.13 KNZ78754.1 - 0.093 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 KNZ78754.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KNZ78754.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain GTP_EFTU_D2 PF03144.25 KNZ78755.1 - 0.00018 21.8 1.0 0.00037 20.8 1.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RVP_2 PF08284.11 KNZ78756.1 - 0.086 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 KNZ78758.1 - 4.7e-05 23.9 0.0 8.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78758.1 - 0.0022 18.6 0.0 0.0042 17.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ78758.1 - 0.071 12.9 0.1 0.27 11.0 0.0 1.8 1 1 1 2 2 2 0 Aspartyl protease zf-CCHC PF00098.23 KNZ78759.1 - 0.039 14.0 1.4 0.073 13.2 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ78759.1 - 0.041 13.6 2.7 0.072 12.8 2.7 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger KRAB PF01352.27 KNZ78759.1 - 1.9 8.2 3.8 7.7 6.3 0.0 2.8 2 1 1 3 3 3 0 KRAB box Retrotran_gag_2 PF14223.6 KNZ78760.1 - 9.2e-11 41.6 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_2 PF14223.6 KNZ78761.1 - 2.8e-11 43.2 0.0 3.8e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type EFG_C PF00679.24 KNZ78762.1 - 3.5e-15 55.8 0.1 6.2e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ78762.1 - 0.054 13.9 0.6 0.15 12.5 0.6 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF305 PF03713.13 KNZ78766.1 - 0.11 12.7 1.2 0.15 12.2 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) bZIP_1 PF00170.21 KNZ78766.1 - 0.17 12.0 3.1 0.34 11.1 2.7 1.8 1 1 0 1 1 1 0 bZIP transcription factor Ax_dynein_light PF10211.9 KNZ78766.1 - 0.2 11.6 3.2 0.36 10.7 3.1 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain TPR_MLP1_2 PF07926.12 KNZ78766.1 - 0.24 11.4 7.4 6.6 6.8 0.1 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 KNZ78767.1 - 0.0036 17.6 5.5 0.0038 17.5 5.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FemAB PF02388.16 KNZ78767.1 - 0.0066 15.4 3.5 0.008 15.1 3.5 1.2 1 0 0 1 1 1 1 FemAB family DUF2968 PF11180.8 KNZ78767.1 - 0.0069 16.0 4.2 0.0071 16.0 3.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2968) XhlA PF10779.9 KNZ78767.1 - 0.014 15.6 2.2 0.014 15.6 2.2 2.7 2 1 1 3 3 3 0 Haemolysin XhlA DUF1664 PF07889.12 KNZ78767.1 - 0.016 15.2 4.7 0.051 13.6 4.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 KNZ78767.1 - 0.017 15.0 13.0 0.028 14.3 13.0 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 KNZ78767.1 - 0.03 14.5 12.6 0.056 13.6 12.6 1.5 1 0 0 1 1 1 0 Tropomyosin like Atg14 PF10186.9 KNZ78767.1 - 0.07 12.2 2.1 0.079 12.0 2.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 BBP1_C PF15272.6 KNZ78767.1 - 0.17 11.7 8.8 0.21 11.4 8.8 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal YabA PF06156.13 KNZ78767.1 - 0.37 11.5 11.3 0.18 12.4 5.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA SOGA PF11365.8 KNZ78767.1 - 0.42 11.8 9.1 0.19 12.8 3.8 2.2 1 1 1 2 2 2 0 Protein SOGA Bap31_Bap29_C PF18035.1 KNZ78767.1 - 0.9 9.6 16.3 2.3 8.3 5.5 3.0 2 1 1 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain ERM PF00769.19 KNZ78767.1 - 1.1 9.0 15.6 0.65 9.8 11.5 2.2 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DUF3332 PF11810.8 KNZ78767.1 - 1.7 8.3 6.9 0.47 10.1 3.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3332) p450 PF00067.22 KNZ78768.1 - 2.8e-46 158.3 0.1 3.7e-23 82.0 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 gag-asp_proteas PF13975.6 KNZ78770.1 - 2.1e-06 28.2 0.0 3.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ78770.1 - 7.3e-06 26.6 0.0 1.4e-05 25.7 0.0 1.4 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 KNZ78770.1 - 0.047 13.5 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 KNZ78771.1 - 9.8e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ78771.1 - 0.0012 18.8 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KNZ78771.1 - 0.0094 16.1 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PIF1 PF05970.14 KNZ78775.1 - 3.7e-20 72.4 0.0 4e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase p450 PF00067.22 KNZ78776.1 - 1e-55 189.4 0.0 1.3e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp_protease_2 PF13650.6 KNZ78777.1 - 0.021 15.5 0.0 0.045 14.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KNZ78777.1 - 0.032 14.8 0.0 0.066 13.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Med1 PF10744.9 KNZ78782.1 - 3.5e-05 23.0 0.1 0.055 12.5 0.0 2.8 3 1 0 3 3 3 2 Mediator of RNA polymerase II transcription subunit 1 Syntaxin PF00804.25 KNZ78783.1 - 0.53 9.9 3.9 0.21 11.3 0.7 1.9 2 0 0 2 2 2 0 Syntaxin Bac_surface_Ag PF01103.23 KNZ78784.1 - 1e-37 130.4 0.1 1.4e-37 129.9 0.1 1.2 1 0 0 1 1 1 1 Surface antigen Palm_thioest PF02089.15 KNZ78785.1 - 3.2e-68 230.2 0.0 3.8e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase BssB_TutG PF18512.1 KNZ78785.1 - 0.0046 16.8 0.2 0.01 15.7 0.2 1.5 1 0 0 1 1 1 1 Benzylsuccinate synthase beta subunit Abhydrolase_1 PF00561.20 KNZ78785.1 - 0.035 13.7 0.0 0.093 12.3 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Nucleos_tra2_C PF07662.13 KNZ78786.1 - 1.5e-68 230.8 3.7 1.5e-68 230.8 3.7 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 KNZ78786.1 - 1.2e-21 77.0 4.6 1.2e-21 77.0 4.6 3.0 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 KNZ78786.1 - 0.02 15.2 15.2 0.021 15.1 3.4 3.3 2 1 0 2 2 2 0 Nucleoside recognition WD40 PF00400.32 KNZ78787.1 - 1.2e-11 44.9 0.7 0.00098 19.9 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat RPA_interact_C PF14768.6 KNZ78788.1 - 0.0018 18.8 0.1 0.0027 18.2 0.1 1.2 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Trp_oprn_chp PF09534.10 KNZ78789.1 - 0.043 13.6 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ipi1_N PF12333.8 KNZ78789.1 - 0.28 11.8 1.4 2.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation MPC PF03650.13 KNZ78790.1 - 1.2e-36 125.2 1.6 3.2e-34 117.4 0.3 2.0 1 1 1 2 2 2 2 Mitochondrial pyruvate carriers DUF3421 PF11901.8 KNZ78791.1 - 8e-21 74.2 1.2 2.4e-13 50.1 0.1 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3421) Kei1 PF08552.11 KNZ78792.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.9 2 1 1 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Tetraspanin PF00335.20 KNZ78792.1 - 0.063 13.0 18.4 0.2 11.4 18.4 1.9 1 1 0 1 1 1 0 Tetraspanin family SID-1_RNA_chan PF13965.6 KNZ78792.1 - 0.2 10.1 2.8 0.25 9.7 2.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 COG5 PF10392.9 KNZ78794.1 - 1.4e-05 25.3 0.0 1.8e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 ALS_ss_C PF10369.9 KNZ78796.1 - 4e-20 71.8 0.4 1.3e-18 66.9 0.1 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 KNZ78796.1 - 3.8e-13 49.0 0.1 6.9e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 KNZ78796.1 - 6.6e-07 29.1 0.0 1.8e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 ACT domain DUF2187 PF09953.9 KNZ78796.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) HMG_box PF00505.19 KNZ78797.1 - 7.8e-07 29.4 0.9 7.8e-07 29.4 0.9 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box Pet100 PF09803.9 KNZ78797.1 - 2.5 8.7 8.4 8.2 7.0 8.4 1.9 1 1 0 1 1 1 0 Pet100 RRM_1 PF00076.22 KNZ78798.1 - 1.3e-10 40.9 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 KNZ78799.1 - 9.6e-37 127.1 3.4 1.3e-36 126.7 3.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ78799.1 - 1.5e-33 116.2 0.0 3.3e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 KNZ78799.1 - 1.1e-05 25.0 0.5 0.00023 20.7 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KNZ78799.1 - 0.00053 20.4 0.5 0.002 18.6 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KNZ78799.1 - 0.0008 19.1 0.3 0.0019 17.9 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ78799.1 - 0.0017 18.6 0.1 0.021 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KNZ78799.1 - 0.003 17.4 0.0 0.01 15.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ78799.1 - 0.0099 15.6 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 KNZ78799.1 - 0.06 12.5 0.2 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit RsgA_GTPase PF03193.16 KNZ78799.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase MTABC_N PF16185.5 KNZ78799.1 - 0.13 11.7 1.0 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF87 PF01935.17 KNZ78799.1 - 0.14 12.2 0.4 2.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain APS_kinase PF01583.20 KNZ78799.1 - 0.18 11.7 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NAD_kinase PF01513.21 KNZ78801.1 - 9.8e-76 254.7 0.0 3.4e-75 253.0 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Q_salvage PF10343.9 KNZ78802.1 - 1.9e-07 31.0 0.0 4.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family YqeY PF09424.10 KNZ78803.1 - 8.7e-13 48.6 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Yqey-like protein zf-rbx1 PF12678.7 KNZ78804.1 - 4.8e-12 46.0 6.4 9.1e-12 45.1 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KNZ78804.1 - 2.1e-09 37.6 10.9 2.5e-08 34.1 10.9 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KNZ78804.1 - 1.2e-07 31.4 1.5 3.1e-07 30.1 1.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ78804.1 - 4.9e-06 26.3 5.9 1.4e-05 24.9 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ78804.1 - 5e-06 26.4 3.6 5e-06 26.4 3.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KNZ78804.1 - 1.7e-05 24.6 4.6 0.00031 20.5 1.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KNZ78804.1 - 0.00022 21.2 5.3 0.00067 19.7 5.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KNZ78804.1 - 0.00064 19.3 1.7 0.0016 18.0 1.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KNZ78804.1 - 0.00093 19.1 5.9 0.0036 17.2 6.2 1.9 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KNZ78804.1 - 0.0014 18.4 5.1 0.0014 18.4 5.1 2.0 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 KNZ78804.1 - 0.002 17.8 1.8 0.002 17.8 1.8 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 KNZ78804.1 - 0.015 15.5 2.0 0.015 15.5 2.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KNZ78804.1 - 0.033 14.4 0.7 0.069 13.3 0.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KNZ78804.1 - 0.38 11.1 3.9 0.72 10.2 3.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KNZ78804.1 - 1.8 8.4 3.7 1.2 9.0 1.4 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.11 KNZ78805.1 - 8.2e-88 295.9 0.0 9.5e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KNZ78805.1 - 3.7e-11 42.9 0.0 8.4e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family SNF2_N PF00176.23 KNZ78806.1 - 4.9e-54 183.4 0.0 8.5e-54 182.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ78806.1 - 1.8e-13 50.8 0.0 4.7e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ78806.1 - 6.4e-10 39.3 0.0 2.1e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KNZ78806.1 - 0.00091 18.5 0.2 0.0017 17.6 0.2 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 KNZ78806.1 - 0.018 15.3 0.2 0.46 10.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Peptidase_M22 PF00814.25 KNZ78807.1 - 3.4e-69 233.6 0.0 3.9e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.6 KNZ78807.1 - 0.17 11.7 0.3 0.35 10.7 0.3 1.5 1 0 0 1 1 1 0 YycC-like protein HbrB PF08539.11 KNZ78808.1 - 7.2e-49 166.0 0.0 3.1e-48 164.0 0.0 1.9 1 1 0 1 1 1 1 HbrB-like Dynamitin PF04912.14 KNZ78809.1 - 6.3e-68 229.9 6.3 7.7e-68 229.6 6.3 1.1 1 0 0 1 1 1 1 Dynamitin AIP3 PF03915.13 KNZ78809.1 - 0.00069 18.8 0.8 0.0012 18.0 0.8 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Laminin_II PF06009.12 KNZ78809.1 - 0.0044 17.0 1.5 0.025 14.6 0.1 2.5 1 1 1 2 2 2 1 Laminin Domain II ABC_tran_CTD PF16326.5 KNZ78809.1 - 0.041 14.1 8.4 0.25 11.6 0.1 4.1 4 0 0 4 4 4 0 ABC transporter C-terminal domain Spc7 PF08317.11 KNZ78809.1 - 0.047 12.6 7.2 0.061 12.2 0.2 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 KNZ78809.1 - 0.07 10.6 2.6 0.35 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 KNZ78809.1 - 0.08 13.2 1.1 19 5.7 0.1 3.5 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rx_N PF18052.1 KNZ78809.1 - 0.081 13.2 6.1 5.9 7.2 0.3 3.5 3 0 0 3 3 3 0 Rx N-terminal domain SKA2 PF16740.5 KNZ78809.1 - 0.097 12.5 3.7 12 5.7 1.0 3.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 SARS_lipid_bind PF09399.10 KNZ78809.1 - 0.1 12.8 0.5 0.97 9.7 0.1 2.3 1 1 0 2 2 2 0 SARS lipid binding protein Cytochrom_B562 PF07361.11 KNZ78809.1 - 0.11 13.1 0.5 1.3 9.7 0.0 2.7 4 0 0 4 4 2 0 Cytochrome b562 Cep57_MT_bd PF06657.13 KNZ78809.1 - 0.12 12.9 5.9 37 4.8 0.0 3.5 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 phiKZ_IP PF12699.7 KNZ78809.1 - 0.13 11.4 1.6 4.5 6.3 0.5 2.6 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins Syntaxin-6_N PF09177.11 KNZ78809.1 - 0.14 12.7 3.3 1.2 9.7 1.1 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 KNZ78809.1 - 0.21 11.6 0.3 3.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 KNZ78809.1 - 0.24 10.7 6.1 2 7.6 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 KNZ78809.1 - 0.65 9.8 2.6 1.9 8.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF724) CENP-H PF05837.12 KNZ78809.1 - 1 9.8 6.7 1.3 9.5 0.2 3.3 3 0 0 3 3 3 0 Centromere protein H (CENP-H) dbPDZ_assoc PF16610.5 KNZ78809.1 - 1.3 9.3 5.4 12 6.1 0.3 2.9 3 0 0 3 3 2 0 Unstructured region between two PDZ domains on Dlg5 APP_E2 PF12925.7 KNZ78809.1 - 1.4 8.6 4.9 0.22 11.2 0.8 1.7 2 0 0 2 2 1 0 E2 domain of amyloid precursor protein COG2 PF06148.11 KNZ78809.1 - 1.5 8.9 7.3 1.9 8.6 0.4 3.4 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6_N PF17675.1 KNZ78809.1 - 1.7 9.2 9.2 58 4.2 7.1 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 KNZ78809.1 - 1.9 8.8 4.3 31 4.9 0.3 3.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 KNZ78809.1 - 4.5 7.3 11.8 0.36 10.9 0.8 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.8 KNZ78809.1 - 4.6 6.8 13.0 3.3 7.3 6.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) SlyX PF04102.12 KNZ78809.1 - 6 7.6 14.8 15 6.3 0.5 4.6 4 0 0 4 4 4 0 SlyX CENP-F_leu_zip PF10473.9 KNZ78809.1 - 6.3 6.8 13.6 9.6 6.2 2.0 4.3 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC53 PF10152.9 KNZ78809.1 - 7.2 7.0 10.0 3.2 8.1 0.4 2.8 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex Jnk-SapK_ap_N PF09744.9 KNZ78809.1 - 9.8 6.4 9.5 0.52 10.5 0.6 2.6 3 0 0 3 3 2 0 JNK_SAPK-associated protein-1 MFS_1 PF07690.16 KNZ78811.1 - 2.2e-12 46.6 38.1 3.1e-12 46.1 38.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5604 PF18300.1 KNZ78811.1 - 0.11 12.5 0.1 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5604) PrgI PF12666.7 KNZ78811.1 - 5.8 7.7 17.5 1.6 9.5 5.8 3.6 1 1 3 4 4 4 0 PrgI family protein Phos_pyr_kin PF08543.12 KNZ78812.1 - 2.8e-09 36.7 0.0 4.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KNZ78812.1 - 9.2e-05 21.9 0.0 0.00054 19.4 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase MCLC PF05934.11 KNZ78813.1 - 9.6 4.8 8.0 14 4.2 8.0 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) 4HBT_2 PF13279.6 KNZ78814.1 - 7.6e-15 55.5 0.0 1.3e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KNZ78814.1 - 4.4e-05 23.8 0.0 7.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KNZ78814.1 - 0.0038 16.5 0.1 0.02 14.2 0.1 1.9 1 1 2 3 3 3 1 Acyl-ACP thioesterase HSF_DNA-bind PF00447.17 KNZ78815.1 - 2.4e-29 101.8 0.7 2.8e-29 101.6 0.7 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Gly-zipper_Omp PF13488.6 KNZ78817.1 - 0.08 13.0 4.7 0.16 12.0 4.7 1.4 1 0 0 1 1 1 0 Glycine zipper DUF5305 PF17231.2 KNZ78817.1 - 0.13 11.6 0.1 0.22 10.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF4293 PF14126.6 KNZ78818.1 - 0.014 15.7 1.6 0.028 14.7 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) START PF01852.19 KNZ78822.1 - 1.4e-13 50.7 0.1 2.3e-07 30.4 0.0 3.7 3 0 0 3 3 3 3 START domain SLT_L PF14718.6 KNZ78823.1 - 0.017 15.3 0.9 0.02 15.0 0.9 1.1 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain CBM_5_12_2 PF14600.6 KNZ78823.1 - 0.085 12.8 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Cellulose-binding domain Asp_protease_2 PF13650.6 KNZ78824.1 - 0.13 12.9 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease IPK PF03770.16 KNZ78825.1 - 3.4e-41 141.3 0.0 5.1e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase FAM176 PF14851.6 KNZ78825.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 KNZ78825.1 - 0.29 11.6 3.8 0.52 10.7 3.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Med11 PF10280.9 KNZ78827.1 - 0.13 12.7 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Mediator complex protein Gly-zipper_Omp PF13488.6 KNZ78828.1 - 2.9 8.0 17.7 3.9 7.6 4.2 2.4 2 0 0 2 2 2 0 Glycine zipper SKG6 PF08693.10 KNZ78829.1 - 0.013 14.9 0.3 0.032 13.7 0.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rax2 PF12768.7 KNZ78829.1 - 0.04 13.4 0.0 0.11 11.9 0.0 1.8 1 1 1 2 2 2 0 Cortical protein marker for cell polarity PTP_tm PF18861.1 KNZ78829.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J stn_TNFRSF12A PF12191.8 KNZ78829.1 - 0.11 12.7 1.8 0.22 11.8 1.8 1.7 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Defensin_int PF17858.1 KNZ78829.1 - 9.8 6.3 8.3 1 9.4 3.1 1.9 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide CAP_GLY PF01302.25 KNZ78830.1 - 8e-26 89.9 0.4 1.4e-25 89.1 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KNZ78830.1 - 1.9e-25 89.1 0.1 5.2e-25 87.7 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.23 KNZ78830.1 - 0.0015 18.2 0.0 0.0052 16.5 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family DUF4340 PF14238.6 KNZ78830.1 - 0.094 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) DUF4988 PF16378.5 KNZ78830.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function AAA PF00004.29 KNZ78831.1 - 1.1e-78 262.1 0.1 9.1e-47 158.8 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ78831.1 - 1.4e-24 85.6 11.0 7.8e-13 48.0 1.0 3.2 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 KNZ78831.1 - 9.5e-21 73.8 0.3 5.8e-20 71.3 0.4 2.3 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KNZ78831.1 - 5.5e-14 52.2 0.0 1.2e-05 25.2 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain CDC48_2 PF02933.17 KNZ78831.1 - 2.9e-11 43.0 0.0 6e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 KNZ78831.1 - 9.8e-11 42.0 0.0 5e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 KNZ78831.1 - 1.5e-10 41.5 0.0 0.00011 22.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KNZ78831.1 - 3.7e-10 39.9 0.0 0.00026 21.0 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ78831.1 - 9.7e-10 39.1 2.1 0.00083 19.8 0.0 4.8 4 2 1 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 KNZ78831.1 - 2.1e-09 37.8 0.1 0.052 13.8 0.0 4.6 3 2 2 5 5 4 2 AAA domain TIP49 PF06068.13 KNZ78831.1 - 4.4e-09 36.0 0.0 0.0025 17.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 KNZ78831.1 - 1e-07 31.8 0.2 3.9e-06 26.8 0.1 2.9 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 KNZ78831.1 - 4.1e-07 29.6 0.3 0.027 13.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KNZ78831.1 - 4.7e-07 29.7 0.0 0.025 14.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 KNZ78831.1 - 5.2e-07 30.3 0.0 0.016 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KNZ78831.1 - 5.4e-07 29.7 0.0 0.018 15.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 KNZ78831.1 - 1.4e-06 28.6 0.0 0.022 15.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 KNZ78831.1 - 3.8e-06 26.5 0.0 0.015 14.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 KNZ78831.1 - 1.1e-05 24.7 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 KNZ78831.1 - 1.4e-05 25.4 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 KNZ78831.1 - 3e-05 23.8 0.0 0.44 10.2 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 KNZ78831.1 - 3.9e-05 23.5 0.1 0.42 10.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 KNZ78831.1 - 0.00015 22.2 0.5 0.74 10.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain ATPase PF06745.13 KNZ78831.1 - 0.00024 20.5 0.1 0.91 8.8 0.0 2.6 2 0 0 2 2 2 2 KaiC DUF815 PF05673.13 KNZ78831.1 - 0.00027 20.2 0.0 0.025 13.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 KNZ78831.1 - 0.00028 20.7 0.0 0.8 9.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KNZ78831.1 - 0.00031 20.7 0.0 0.34 10.9 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KNZ78831.1 - 0.0004 20.9 0.0 0.22 12.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter ResIII PF04851.15 KNZ78831.1 - 0.00041 20.4 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KNZ78831.1 - 0.00062 19.1 0.0 0.53 9.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 KNZ78831.1 - 0.00072 19.4 0.0 0.27 11.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KNZ78831.1 - 0.0011 18.5 3.9 0.49 9.8 0.0 2.6 3 0 0 3 3 2 2 PhoH-like protein AAA_11 PF13086.6 KNZ78831.1 - 0.0011 18.8 1.2 0.93 9.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain UFD1 PF03152.14 KNZ78831.1 - 0.0026 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AAA_30 PF13604.6 KNZ78831.1 - 0.0028 17.4 0.4 2.5 7.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 KNZ78831.1 - 0.0033 17.5 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 KNZ78831.1 - 0.0036 17.6 2.8 4.2 7.7 0.0 4.1 4 1 0 5 5 5 0 AAA domain AAA_25 PF13481.6 KNZ78831.1 - 0.0056 16.3 1.2 1 8.9 0.1 2.9 2 2 0 2 2 2 1 AAA domain Molydop_binding PF01568.21 KNZ78831.1 - 0.0059 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain ATPase_2 PF01637.18 KNZ78831.1 - 0.0062 16.5 0.0 4.7 7.0 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 KNZ78831.1 - 0.0071 15.4 0.0 0.25 10.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 KNZ78831.1 - 0.0074 15.6 0.0 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 KNZ78831.1 - 0.01 15.8 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 KNZ78831.1 - 0.014 14.6 0.0 0.71 9.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Bac_DnaA PF00308.18 KNZ78831.1 - 0.022 14.6 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Bacterial dnaA protein IPT PF01745.16 KNZ78831.1 - 0.036 13.5 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Cytidylate_kin PF02224.18 KNZ78831.1 - 0.05 13.3 0.0 7.4 6.2 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase NTPase_1 PF03266.15 KNZ78831.1 - 0.064 13.2 1.5 5.7 6.8 0.0 3.7 4 0 0 4 4 4 0 NTPase KAP_NTPase PF07693.14 KNZ78831.1 - 0.08 12.2 0.0 0.84 8.8 0.0 2.3 2 1 1 3 3 3 0 KAP family P-loop domain PIF1 PF05970.14 KNZ78831.1 - 0.24 10.5 0.2 8.3 5.5 0.0 3.2 4 0 0 4 4 4 0 PIF1-like helicase Hydin_ADK PF17213.3 KNZ78831.1 - 0.85 9.9 2.3 38 4.5 0.0 3.5 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain DAGAT PF03982.13 KNZ78832.1 - 2.9e-102 341.6 0.0 3.5e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Fe_dep_repr_C PF02742.15 KNZ78834.1 - 0.036 14.2 0.1 0.066 13.3 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Internalin_N PF12354.8 KNZ78834.1 - 0.2 11.7 0.1 0.39 10.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Peptidase_C21 PF05381.12 KNZ78835.1 - 0.032 14.6 0.3 0.05 14.0 0.3 1.4 1 0 0 1 1 1 0 Tymovirus endopeptidase Lipase_3 PF01764.25 KNZ78837.1 - 1.2e-17 64.1 0.1 1.6e-17 63.7 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KNZ78837.1 - 0.0017 19.0 0.1 0.002 18.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KNZ78837.1 - 0.0031 17.3 0.1 0.0047 16.8 0.1 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KNZ78837.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ78837.1 - 0.041 13.1 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Qn_am_d_aIII PF09099.10 KNZ78837.1 - 0.064 13.7 0.3 0.12 12.8 0.3 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III LIDHydrolase PF10230.9 KNZ78837.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 KNZ78837.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cellulase PF00150.18 KNZ78838.1 - 3.6e-10 39.8 0.0 9.5e-10 38.4 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BRE1 PF08647.11 KNZ78839.1 - 0.095 12.8 3.0 0.089 12.9 0.7 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase NAD_binding_10 PF13460.6 KNZ78840.1 - 3.4e-05 23.8 0.2 4.5e-05 23.4 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 KNZ78840.1 - 5.6e-05 23.6 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 KNZ78840.1 - 0.054 12.9 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Staph_haemo PF05480.11 KNZ78840.1 - 0.1 12.4 0.0 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 Staphylococcus haemolytic protein Sacchrp_dh_NADP PF03435.18 KNZ78840.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ytp1 PF10355.9 KNZ78841.1 - 6.5e-60 202.7 19.2 4.7e-59 199.9 16.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KNZ78841.1 - 2.4e-27 94.8 0.1 2.4e-27 94.8 0.1 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KNZ78841.1 - 0.0015 18.7 4.4 0.0015 18.7 4.4 3.7 3 1 0 3 3 3 1 Eukaryotic cytochrome b561 Tetraspanin PF00335.20 KNZ78841.1 - 0.83 9.3 0.0 0.83 9.3 0.0 3.7 3 1 0 4 4 4 0 Tetraspanin family Lactamase_B_2 PF12706.7 KNZ78842.1 - 2.2e-11 43.7 3.0 1.2e-10 41.2 1.9 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 KNZ78842.1 - 1.8e-09 37.2 0.0 1.5e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.27 KNZ78842.1 - 0.24 11.4 1.2 0.72 9.8 1.2 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 KNZ78843.1 - 1.6e-28 99.7 50.9 1.1e-27 96.9 23.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KNZ78843.1 - 3.5e-08 32.7 7.9 0.00018 20.5 0.7 2.4 2 0 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 KNZ78843.1 - 4.3e-07 29.1 24.0 3.1e-06 26.3 5.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 KNZ78843.1 - 0.00025 19.6 0.9 0.0005 18.6 0.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MRI PF15325.6 KNZ78844.1 - 0.15 13.2 0.5 0.45 11.6 0.5 1.9 1 0 0 1 1 1 0 Modulator of retrovirus infection MFS_1 PF07690.16 KNZ78845.1 - 6.3e-25 87.8 20.7 6.3e-25 87.8 20.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ78845.1 - 9.2e-06 24.8 22.0 6.8e-05 21.9 22.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KNZ78845.1 - 3.7e-05 22.3 0.7 7.3e-05 21.4 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 KNZ78845.1 - 5.8e-05 22.1 11.2 0.013 14.3 1.8 2.4 2 0 0 2 2 2 2 MFS_1 like family PDT PF00800.18 KNZ78846.1 - 1.3e-47 161.9 0.0 1.8e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase zf-CCCH PF00642.24 KNZ78847.1 - 3.5e-16 58.7 21.6 2.1e-05 24.3 0.6 5.3 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNZ78847.1 - 1.1e-11 44.4 26.4 1e-06 28.6 2.1 5.0 5 0 0 5 5 5 3 Zinc finger domain Torus PF16131.5 KNZ78847.1 - 4.4e-07 30.6 19.9 0.00049 20.8 0.4 4.5 1 1 4 5 5 5 3 Torus domain zf-CCCH_4 PF18044.1 KNZ78847.1 - 2.5e-05 23.9 0.4 2.5e-05 23.9 0.4 5.1 6 0 0 6 6 6 1 CCCH-type zinc finger zf-CCHC PF00098.23 KNZ78847.1 - 0.00037 20.4 3.7 0.00037 20.4 3.7 2.9 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ78847.1 - 0.0031 17.4 0.4 0.0079 16.1 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.6 KNZ78847.1 - 0.0085 16.5 0.3 0.0085 16.5 0.3 5.3 6 0 0 6 6 6 3 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KNZ78847.1 - 1.7 8.9 14.7 2.8 8.2 0.4 3.8 1 1 3 4 4 4 0 Zinc-finger containing family UPF0047 PF01894.17 KNZ78848.1 - 2.9e-30 104.8 0.1 3.2e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 KNZ78849.1 - 0.018 14.1 0.1 0.081 11.9 0.0 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain VKOR PF07884.14 KNZ78849.1 - 0.038 14.2 0.6 0.06 13.5 0.6 1.2 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Euplotes_phero PF05842.11 KNZ78850.1 - 0.2 12.2 1.7 0.47 11.0 1.7 1.6 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Ras PF00071.22 KNZ78851.1 - 7.4e-35 119.9 0.0 8.5e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ78851.1 - 5e-12 46.1 0.0 6.7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF423 PF04241.15 KNZ78853.1 - 4.9e-20 71.5 1.8 7.5e-20 70.9 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Spb1_C PF07780.12 KNZ78854.1 - 1.2e-76 257.0 19.3 1.2e-76 257.0 19.3 2.5 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 KNZ78854.1 - 1.7e-56 191.1 0.0 9.6e-56 188.7 0.0 2.3 3 0 0 3 3 3 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KNZ78854.1 - 9e-46 155.7 2.4 9e-46 155.7 2.4 4.9 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) SLS PF14611.6 KNZ78855.1 - 6.6e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator zf-RVT PF13966.6 KNZ78856.1 - 0.0071 17.0 2.8 0.015 16.0 0.8 2.0 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase Zn_Tnp_IS1595 PF12760.7 KNZ78856.1 - 0.068 13.2 1.1 0.3 11.1 1.1 2.2 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF2085 PF09858.9 KNZ78856.1 - 0.071 13.6 0.1 0.095 13.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2085) TF_Zn_Ribbon PF08271.12 KNZ78856.1 - 0.091 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding NGF PF00243.18 KNZ78856.1 - 0.14 12.4 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 Nerve growth factor family Abhydrolase_1 PF00561.20 KNZ78857.1 - 2.5e-16 60.1 0.2 1.9e-13 50.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ78857.1 - 5.2e-12 46.8 0.0 6.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ78857.1 - 6.6e-09 35.4 0.0 3.1e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KNZ78857.1 - 8.3e-06 26.1 0.0 9.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 KNZ78857.1 - 0.0042 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3328 PF11807.8 KNZ78858.1 - 6.1e-13 49.1 0.0 6.6e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 KNZ78860.1 - 3.4e-23 82.6 2.4 3.9e-23 82.4 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Chromo PF00385.24 KNZ78862.1 - 8.1e-11 41.7 0.6 1.1e-10 41.2 0.6 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SF3a60_bindingd PF12108.8 KNZ78862.1 - 0.021 14.7 0.5 0.021 14.7 0.5 1.7 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain F-box PF00646.33 KNZ78863.1 - 8.8e-06 25.5 0.5 3.3e-05 23.6 0.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ78863.1 - 0.0016 18.3 0.1 0.0045 16.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like TIM PF00121.18 KNZ78864.1 - 8e-87 290.6 0.0 9.1e-87 290.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 KNZ78864.1 - 0.0011 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 CutC family GLE1 PF07817.13 KNZ78865.1 - 2.2e-47 161.4 0.0 4.1e-47 160.5 0.0 1.4 1 0 0 1 1 1 1 GLE1-like protein Biotin_lipoyl PF00364.22 KNZ78866.1 - 2.8e-17 62.3 0.6 5.1e-17 61.5 0.2 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KNZ78866.1 - 2.5e-08 34.1 0.0 8.5e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Adhesin_P1 PF03257.13 KNZ78866.1 - 0.033 14.7 0.2 0.12 12.9 0.1 1.9 2 0 0 2 2 2 0 Mycoplasma adhesin P1 Sterol-sensing PF12349.8 KNZ78867.1 - 6.3e-36 123.5 8.4 1.4e-35 122.4 8.4 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KNZ78867.1 - 1.4e-09 36.6 3.2 2.1e-09 36.1 3.2 1.1 1 0 0 1 1 1 1 Patched family DUF1077 PF06417.12 KNZ78868.1 - 1.4e-34 118.6 1.0 1.9e-34 118.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Sen15 PF09631.10 KNZ78869.1 - 1.6e-18 66.8 0.0 2.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Oxidored_molyb PF00174.19 KNZ78870.1 - 1.5e-38 132.1 0.1 3.5e-24 85.3 0.2 2.7 3 0 0 3 3 3 2 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KNZ78870.1 - 3.2e-22 79.0 1.7 6.2e-22 78.1 1.7 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain HCBP_related PF06594.11 KNZ78870.1 - 0.025 14.5 0.1 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain RRM_1 PF00076.22 KNZ78871.1 - 3.7e-35 119.6 0.0 1.2e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 KNZ78871.1 - 0.021 14.5 0.2 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain RRM_5 PF13893.6 KNZ78871.1 - 0.041 13.5 0.0 9.4 5.8 0.0 2.2 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ78871.1 - 0.073 13.2 0.0 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif Ras PF00071.22 KNZ78872.1 - 3e-54 183.0 0.0 3.5e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ78872.1 - 2.7e-19 69.6 0.0 3.8e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ78872.1 - 8.7e-08 31.8 0.0 1.2e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ78872.1 - 0.034 13.7 0.1 0.22 11.0 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PET117 PF15786.5 KNZ78872.1 - 0.058 13.7 0.0 0.088 13.1 0.0 1.3 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial WD40 PF00400.32 KNZ78873.1 - 9.1e-05 23.2 6.3 0.0017 19.2 0.2 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78873.1 - 0.00016 21.9 0.1 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain CMD PF02627.20 KNZ78874.1 - 0.00014 21.8 0.0 0.0003 20.8 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family CMD PF02627.20 KNZ78875.1 - 0.072 13.2 0.0 0.52 10.4 0.0 2.4 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family Ribonuclease_3 PF00636.26 KNZ78876.1 - 5.9e-42 142.6 0.0 1e-21 77.5 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KNZ78876.1 - 2.6e-25 89.1 0.0 8.2e-13 48.6 0.0 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 KNZ78876.1 - 2.3e-16 60.1 0.0 3.7e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.14 KNZ78876.1 - 2.7e-16 59.5 0.0 5.7e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.15 KNZ78876.1 - 2.7e-14 53.6 0.0 5.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNZ78876.1 - 2e-13 50.5 0.0 3.3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KNZ78876.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KNZ78876.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CDC45 PF02724.14 KNZ78877.1 - 0.087 11.1 1.0 0.14 10.4 1.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 KNZ78877.1 - 1.3 7.5 11.2 0.029 13.0 4.7 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SCHIP-1 PF10148.9 KNZ78879.1 - 0.043 13.4 0.2 0.043 13.4 0.2 1.0 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Terpene_synth_C PF03936.16 KNZ78880.1 - 6.9e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DNA_pol_A_exo1 PF01612.20 KNZ78882.1 - 8.2e-09 35.4 0.2 0.0016 18.2 0.0 3.2 2 1 1 3 3 3 2 3'-5' exonuclease p450 PF00067.22 KNZ78883.1 - 3.1e-58 197.7 0.0 2.1e-57 194.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 AGH PF17558.2 KNZ78883.1 - 0.088 13.0 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Androgenic gland hormone Ras PF00071.22 KNZ78884.1 - 3.8e-54 182.6 0.0 4.6e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ78884.1 - 1.4e-21 76.9 0.0 2.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ78884.1 - 2.3e-06 27.2 0.0 4.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KNZ78884.1 - 0.0049 16.3 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Amino_oxidase PF01593.24 KNZ78885.1 - 3.5e-73 247.4 0.1 1.7e-70 238.6 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ78885.1 - 1.3e-11 44.6 0.2 3.1e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KNZ78885.1 - 9.7e-05 21.8 0.4 0.0003 20.2 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 KNZ78885.1 - 0.0005 19.5 3.6 0.0019 17.6 3.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KNZ78885.1 - 0.00086 19.0 0.4 0.002 17.8 0.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ78885.1 - 0.0014 17.8 1.3 0.0017 17.5 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ78885.1 - 0.0021 17.4 0.0 0.016 14.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KNZ78885.1 - 0.0037 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KNZ78885.1 - 0.028 15.0 0.3 0.12 12.9 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNZ78885.1 - 0.037 13.1 1.6 0.33 10.0 0.2 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KNZ78885.1 - 0.053 12.2 0.1 0.089 11.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF2461 PF09365.10 KNZ78886.1 - 8.9e-68 228.3 0.0 1.5e-37 129.6 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical protein (DUF2461) p47_phox_C PF08944.11 KNZ78886.1 - 0.083 12.3 0.3 0.22 11.0 0.3 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain DNA_pol_A_exo1 PF01612.20 KNZ78887.1 - 2.2e-10 40.5 0.0 6.6e-10 39.0 0.0 1.7 1 1 0 1 1 1 1 3'-5' exonuclease Fungal_trans PF04082.18 KNZ78888.1 - 1.7e-18 66.6 0.0 3.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ78888.1 - 0.0025 17.9 4.7 0.0053 16.9 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KNZ78889.1 - 0.00025 20.8 0.0 0.00071 19.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ78889.1 - 0.0056 16.5 0.0 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 F-box domain TPMT PF05724.11 KNZ78890.1 - 2.7e-27 95.8 0.0 6.4e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KNZ78890.1 - 1.6e-11 44.2 0.0 2.9e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ78890.1 - 3.8e-10 40.3 0.0 5.8e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ78890.1 - 1.9e-07 31.8 0.0 5.9e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ78890.1 - 1.3e-06 29.0 0.0 3e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ78890.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KNZ78890.1 - 0.0049 16.9 0.0 0.006 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ78890.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 KNZ78890.1 - 0.2 11.1 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain TehB PF03848.14 KNZ78890.1 - 0.21 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB HMG_box PF00505.19 KNZ78892.1 - 6.3e-11 42.5 0.4 6.3e-11 42.5 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ78892.1 - 0.00017 22.1 0.1 0.00017 22.1 0.1 1.8 2 0 0 2 2 2 1 HMG-box domain MATalpha_HMGbox PF04769.12 KNZ78892.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box FAM167 PF11652.8 KNZ78894.1 - 0.036 14.5 0.1 0.05 14.1 0.1 1.3 1 0 0 1 1 1 0 FAM167 HsbA PF12296.8 KNZ78895.1 - 5.7e-18 65.5 7.6 7.8e-18 65.0 7.6 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A SF3a60_bindingd PF12108.8 KNZ78895.1 - 0.047 13.6 1.3 0.055 13.4 0.3 1.6 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Baculo_PEP_C PF04513.12 KNZ78895.1 - 0.064 13.3 5.1 0.16 12.0 5.0 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMG_box PF00505.19 KNZ78898.1 - 3.7e-13 49.7 0.7 7.3e-13 48.7 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 KNZ78898.1 - 0.00075 18.9 0.3 0.0013 18.1 0.3 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box_2 PF09011.10 KNZ78898.1 - 0.0013 19.2 0.2 0.0013 19.2 0.2 1.7 2 0 0 2 2 2 1 HMG-box domain BTB PF00651.31 KNZ78899.1 - 6e-07 29.7 0.0 1.4e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 KNZ78900.1 - 1e-32 113.4 56.1 1.4e-32 113.0 45.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Fzo_mitofusin PF04799.13 KNZ78900.1 - 0.27 10.8 0.5 0.55 9.8 0.5 1.4 1 0 0 1 1 1 0 fzo-like conserved region Pkinase PF00069.25 KNZ78904.1 - 2.1e-45 155.1 0.0 5.4e-45 153.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ78904.1 - 5.8e-15 55.3 0.0 3.4e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNZ78904.1 - 1e-06 28.3 0.0 0.004 16.5 0.0 2.4 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KNZ78904.1 - 0.0023 17.9 0.1 0.029 14.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ78904.1 - 0.0066 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain MraZ PF02381.18 KNZ78904.1 - 0.062 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 MraZ protein, putative antitoxin-like MSG PF02349.15 KNZ78904.1 - 0.22 11.8 3.1 0.45 10.7 3.1 1.5 1 0 0 1 1 1 0 Major surface glycoprotein Attractin PF08037.11 KNZ78904.1 - 6.6 6.8 11.5 23 5.1 11.5 1.9 1 1 0 1 1 1 0 Attractin family Peptidase_S8 PF00082.22 KNZ78905.1 - 9.4e-17 61.2 3.0 2.9e-16 59.6 3.0 1.8 1 1 0 1 1 1 1 Subtilase family Plavaka PF18759.1 KNZ78906.1 - 0.00038 19.8 0.0 0.00084 18.6 0.0 1.5 1 1 0 1 1 1 1 Plavaka transposase HpcH_HpaI PF03328.14 KNZ78907.1 - 1.1e-29 103.1 0.0 1.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 KNZ78907.1 - 0.0022 16.9 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DUF455 PF04305.14 KNZ78909.1 - 1.2e-93 313.2 0.0 1.5e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 KNZ78909.1 - 7.3e-05 22.6 0.1 0.00016 21.5 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Myelin_MBP PF01669.17 KNZ78909.1 - 0.14 12.8 0.3 0.25 12.0 0.3 1.3 1 0 0 1 1 1 0 Myelin basic protein GIDA PF01134.22 KNZ78912.1 - 2.3e-117 392.4 0.0 2.7e-117 392.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KNZ78912.1 - 1.5e-60 205.0 0.0 2.3e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain AAA_lid_3 PF17862.1 KNZ78912.1 - 0.11 12.3 0.0 0.67 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA+ lid domain ATG22 PF11700.8 KNZ78914.1 - 1.9e-141 472.0 18.8 6.2e-141 470.3 16.2 1.9 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KNZ78914.1 - 3.8e-08 32.7 45.5 0.00018 20.5 5.5 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 KNZ78915.1 - 3.7e-13 49.7 0.0 4.8e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ78915.1 - 2.7e-12 47.8 0.1 4e-12 47.2 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ78915.1 - 3.4e-11 42.9 0.0 9.7e-11 41.4 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KNZ78915.1 - 0.13 11.9 0.0 0.38 10.4 0.0 1.8 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Med25_VWA PF11265.8 KNZ78916.1 - 0.00033 20.6 0.0 0.0032 17.3 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 25 von Willebrand factor type A WD40 PF00400.32 KNZ78917.1 - 7.3e-43 143.7 17.9 3.1e-08 34.1 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ78917.1 - 1.8e-05 24.9 0.5 0.42 10.9 0.1 4.6 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KNZ78917.1 - 0.0032 17.5 0.2 3.2 7.8 0.0 3.8 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 KNZ78917.1 - 0.009 14.8 0.2 2.9 6.5 0.1 3.7 1 1 3 4 4 4 1 Nup133 N terminal like Nup160 PF11715.8 KNZ78917.1 - 0.048 12.3 0.8 13 4.3 0.1 3.3 1 1 2 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KNZ78917.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 WD40-like domain TFIIS_M PF07500.14 KNZ78918.1 - 2.6e-33 114.8 0.7 2.6e-33 114.8 0.7 2.5 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KNZ78918.1 - 5.2e-11 42.2 5.9 8.8e-11 41.5 5.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KNZ78918.1 - 4.1e-10 39.5 1.1 4.1e-10 39.5 1.1 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TSNAXIP1_N PF15739.5 KNZ78918.1 - 3.4 8.1 7.2 0.19 12.1 0.6 2.3 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus FtsH_ext PF06480.15 KNZ78920.1 - 2.2 8.6 7.9 2.7 8.4 0.4 3.4 3 0 0 3 3 3 0 FtsH Extracellular DRY_EERY PF09750.9 KNZ78923.1 - 0.0024 18.2 3.0 0.0083 16.4 3.0 1.9 1 1 0 1 1 1 1 Alternative splicing regulator IBB PF01749.20 KNZ78923.1 - 3.3 8.2 11.0 1.2 9.7 4.1 3.0 3 0 0 3 3 3 0 Importin beta binding domain Peptidase_M48_N PF16491.5 KNZ78924.1 - 1.4e-60 204.3 7.0 1.4e-60 204.3 7.0 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KNZ78924.1 - 1.5e-36 126.0 0.0 3.2e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KNZ78924.1 - 0.0077 15.5 0.5 0.015 14.5 0.5 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 SprT-like PF10263.9 KNZ78924.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 SprT-like family DUF4131 PF13567.6 KNZ78924.1 - 8.7 6.0 8.6 9.2 5.9 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Rad60-SLD PF11976.8 KNZ78925.1 - 1.4e-08 34.4 0.0 3.3e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KNZ78925.1 - 0.00016 21.4 0.0 0.00065 19.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family PhyH PF05721.13 KNZ78928.1 - 5.6e-11 43.1 0.0 8.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_4 PF12799.7 KNZ78929.1 - 0.13 12.7 10.5 18 5.9 0.3 5.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Sulfate_transp PF00916.20 KNZ78930.1 - 5.7e-60 203.1 14.8 5.7e-60 203.1 14.8 1.5 2 0 0 2 2 2 1 Sulfate permease family cNMP_binding PF00027.29 KNZ78930.1 - 1.4e-11 44.3 0.0 3.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KNZ78930.1 - 8.8e-10 38.2 0.0 1.9e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KNZ78930.1 - 0.006 17.0 3.3 0.006 17.0 3.3 3.3 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily DUF373 PF04123.13 KNZ78930.1 - 8.5 5.7 12.5 4 6.8 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) NUDIX_2 PF13869.6 KNZ78931.1 - 8.4e-82 273.3 0.0 1e-81 273.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase RhoGEF PF00621.20 KNZ78932.1 - 5e-21 75.8 0.1 7.9e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PRIMA1 PF16101.5 KNZ78932.1 - 0.3 11.1 3.5 0.51 10.4 1.6 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Abhydrolase_3 PF07859.13 KNZ78933.1 - 1.2e-15 58.0 0.1 2.8e-15 56.7 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KNZ78933.1 - 1.2e-08 34.3 0.0 4.2e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.11 KNZ78933.1 - 4.9e-06 25.8 0.0 8.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 KNZ78933.1 - 0.00014 20.9 0.0 0.00032 19.7 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KNZ78933.1 - 0.00047 19.7 0.0 0.034 13.6 0.0 2.6 2 1 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KNZ78933.1 - 0.0044 16.3 0.1 0.0089 15.3 0.1 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ78933.1 - 0.012 16.2 1.1 0.019 15.5 1.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1057 PF06342.12 KNZ78933.1 - 0.098 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DIOX_N PF14226.6 KNZ78934.1 - 6.7e-26 91.4 0.0 1.1e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ78934.1 - 4e-20 72.2 0.0 6.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidase02_C PF12123.8 KNZ78934.1 - 0.081 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF2292 PF10055.9 KNZ78934.1 - 0.18 11.5 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2292) Questin_oxidase PF14027.6 KNZ78935.1 - 4.5e-91 305.9 0.0 5.7e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Questin oxidase-like EPL1 PF10513.9 KNZ78936.1 - 1.8e-22 80.4 1.1 8e-22 78.3 0.1 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like Lebercilin PF15619.6 KNZ78936.1 - 0.069 12.8 3.5 0.13 11.9 3.5 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Xan_ur_permease PF00860.20 KNZ78937.1 - 1.6e-29 102.8 31.3 1.5e-26 93.0 31.3 2.6 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 KNZ78937.1 - 0.011 16.1 6.7 0.011 16.1 6.7 3.0 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 KNZ78937.1 - 2.2 8.0 8.2 0.11 12.1 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) F-box-like PF12937.7 KNZ78938.1 - 4.1e-08 33.0 0.1 1.1e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ78938.1 - 0.0048 16.7 0.1 0.015 15.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KNZ78938.1 - 0.067 13.1 1.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 F-box Questin_oxidase PF14027.6 KNZ78939.1 - 1.9e-89 300.6 0.2 2.2e-89 300.3 0.2 1.0 1 0 0 1 1 1 1 Questin oxidase-like Cyt-b5 PF00173.28 KNZ78940.1 - 2e-12 47.1 0.0 2.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.18 KNZ78941.1 - 6.1e-11 41.9 0.5 1.2e-10 40.9 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLD5_C PF16922.5 KNZ78942.1 - 5.9e-10 39.2 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 KNZ78942.1 - 0.00098 19.6 0.4 0.0022 18.5 0.4 1.7 1 1 0 1 1 1 1 GINS complex protein Herpes_UL14 PF03580.14 KNZ78942.1 - 0.021 15.1 1.7 0.035 14.4 1.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL14-like protein TilS PF09179.11 KNZ78942.1 - 0.051 14.1 2.3 9.7 6.8 0.5 3.4 2 2 0 2 2 2 0 TilS substrate binding domain Helicase_Sgs1 PF11408.8 KNZ78942.1 - 0.08 13.0 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Sgs1 RecQ helicase CBFD_NFYB_HMF PF00808.23 KNZ78943.1 - 1.4e-12 47.7 2.0 9.3e-12 45.1 2.0 2.1 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF5427 PF10310.9 KNZ78943.1 - 0.022 13.7 1.8 0.028 13.4 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Tub_N PF16322.5 KNZ78943.1 - 1.5 9.2 11.2 2.1 8.7 11.2 1.5 1 1 0 1 1 1 0 Tubby N-terminal CPSase_L_D2 PF02786.17 KNZ78945.1 - 2.2e-116 386.7 0.1 2.9e-83 278.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.28 KNZ78945.1 - 1.8e-47 161.6 0.0 2.2e-46 158.0 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KNZ78945.1 - 6.5e-46 156.0 0.0 1.4e-45 155.0 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KNZ78945.1 - 6.4e-41 139.5 0.1 1.5e-40 138.4 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain PF00988.22 KNZ78945.1 - 1.6e-32 112.0 0.0 4.5e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace PF00185.24 KNZ78945.1 - 1.5e-28 99.9 0.0 1.2e-27 96.9 0.0 2.4 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 KNZ78945.1 - 4.5e-19 68.8 0.1 1.8e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 KNZ78945.1 - 1.9e-17 63.2 0.0 8.6e-17 61.1 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATP-grasp PF02222.22 KNZ78945.1 - 6.4e-17 61.6 0.0 1.9e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KNZ78945.1 - 4.9e-10 39.2 0.1 0.00046 19.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 KNZ78945.1 - 1.4e-05 25.2 0.1 0.037 14.1 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 KNZ78945.1 - 3.2e-05 23.8 0.1 0.0014 18.4 0.1 2.7 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KNZ78945.1 - 0.00013 21.8 0.1 0.16 11.8 0.0 4.8 6 0 0 6 6 6 1 DJ-1/PfpI family RimK PF08443.11 KNZ78945.1 - 0.0024 17.5 0.0 0.91 9.1 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 KNZ78945.1 - 0.0035 16.8 0.0 3.4 7.1 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 KNZ78945.1 - 0.019 14.8 0.1 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 KNZ78945.1 - 0.29 11.4 1.6 12 6.2 0.0 3.6 4 1 1 5 5 4 0 TrkA-N domain Tubulin PF00091.25 KNZ78946.1 - 4.5e-68 229.3 0.0 9.3e-68 228.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KNZ78946.1 - 8.4e-43 145.5 0.1 1.3e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KNZ78946.1 - 4.2e-06 27.1 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KNZ78946.1 - 0.00092 18.5 0.0 0.018 14.2 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KNZ78946.1 - 0.016 14.9 0.0 0.036 13.7 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Hydrophobin PF01185.18 KNZ78947.1 - 1.4e-18 67.2 5.5 1.7e-18 67.0 5.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CLIP_SPH_mas PF18398.1 KNZ78947.1 - 0.17 12.3 7.5 0.41 11.1 1.1 2.3 2 0 0 2 2 2 0 Clip-domain serine protease homolog masquerade DUF3433 PF11915.8 KNZ78948.1 - 5.2e-13 49.3 1.6 1.4e-12 47.9 1.6 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) Zip PF02535.22 KNZ78949.1 - 1.5e-49 169.0 6.8 6.4e-49 167.0 6.8 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter 7TM_GPCR_Srt PF10321.9 KNZ78949.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt F_bP_aldolase PF01116.20 KNZ78950.1 - 6.5e-67 225.9 0.0 8.7e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Epimerase PF01370.21 KNZ78950.1 - 2.4e-14 53.4 0.0 6.6e-14 51.9 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KNZ78950.1 - 2.1e-09 37.3 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KNZ78950.1 - 0.005 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KNZ78950.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KNZ78950.1 - 0.012 14.8 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Fungal_trans PF04082.18 KNZ78951.1 - 4.8e-10 38.9 0.1 1e-09 37.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain EamA PF00892.20 KNZ78952.1 - 1.3e-28 99.9 27.2 3.5e-17 62.9 7.8 2.7 2 1 1 3 3 3 3 EamA-like transporter family DUF2070 PF09843.9 KNZ78952.1 - 0.041 12.2 21.2 0.11 10.7 5.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) DUF1616 PF07760.11 KNZ78952.1 - 0.061 12.7 1.3 0.092 12.1 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF4244 PF14029.6 KNZ78954.1 - 0.19 11.2 0.2 0.19 11.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) PIF1 PF05970.14 KNZ78955.1 - 1.7e-34 119.6 0.5 1.9e-34 119.4 0.5 1.1 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ78955.1 - 0.0049 16.6 0.0 0.0098 15.6 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UvrD_C_2 PF13538.6 KNZ78955.1 - 0.038 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ78956.1 - 6e-31 107.9 0.0 7.5e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ78956.1 - 0.0038 17.6 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ78956.1 - 0.0045 17.0 0.0 0.0047 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KNZ78956.1 - 0.016 14.9 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ78956.1 - 0.018 14.6 0.2 0.028 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain Troponin PF00992.20 KNZ78956.1 - 0.046 14.0 0.1 0.062 13.6 0.1 1.1 1 0 0 1 1 1 0 Troponin DUF2791 PF10923.8 KNZ78956.1 - 0.046 12.6 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RNA_helicase PF00910.22 KNZ78956.1 - 0.11 12.9 0.1 0.36 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KNZ78956.1 - 0.12 12.8 0.7 3.2 8.2 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Helitron_like_N PF14214.6 KNZ78957.1 - 1.4e-23 84.1 0.0 1.8e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIG-X PF08320.12 KNZ78958.1 - 0.024 14.6 0.5 0.054 13.4 0.2 1.6 1 1 1 2 2 2 0 PIG-X / PBN1 zf-C2H2_aberr PF17017.5 KNZ78960.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-HYPF PF07503.12 KNZ78960.1 - 4.4 7.2 4.6 0.82 9.5 0.5 1.9 2 0 0 2 2 2 0 HypF finger Pkinase_Tyr PF07714.17 KNZ78962.1 - 1.5e-37 129.3 0.0 2.7e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ78962.1 - 8.5e-33 113.8 0.0 1.3e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Patatin PF01734.22 KNZ78962.1 - 3e-11 43.9 0.7 2.1e-10 41.1 0.7 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Kinase-like PF14531.6 KNZ78962.1 - 0.003 16.9 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Patatin PF01734.22 KNZ78963.1 - 7.2e-22 78.6 0.0 3.1e-21 76.5 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Retrotran_gag_2 PF14223.6 KNZ78964.1 - 7e-14 51.7 0.4 4.4e-07 29.7 0.1 2.2 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KNZ78964.1 - 0.00094 19.2 1.0 0.0016 18.4 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ78964.1 - 0.001 18.7 1.2 0.0019 17.9 1.2 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger eIF3g PF12353.8 KNZ78964.1 - 0.027 14.9 1.2 0.041 14.3 1.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Chromo PF00385.24 KNZ78966.1 - 1e-13 51.0 0.2 1.2e-13 50.7 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain OCD_Mu_crystall PF02423.15 KNZ78967.1 - 1.3e-21 76.8 0.4 2e-21 76.2 0.4 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KNZ78967.1 - 0.00081 19.5 0.0 0.0037 17.3 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cys_Met_Meta_PP PF01053.20 KNZ78970.1 - 1.8e-137 457.9 0.0 2.1e-137 457.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KNZ78970.1 - 1.3e-07 31.2 0.2 4.1e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KNZ78970.1 - 7.1e-07 28.5 0.3 1.2e-06 27.7 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNZ78970.1 - 0.0086 15.4 0.1 0.025 13.9 0.1 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 KNZ78970.1 - 0.023 13.5 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 KNZ78970.1 - 0.032 12.8 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase ABC_sub_bind PF04392.12 KNZ78970.1 - 0.055 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 ABC transporter substrate binding protein TPR_12 PF13424.6 KNZ78971.1 - 8.6e-14 51.6 6.3 0.00017 21.8 0.2 5.3 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ78971.1 - 3.1e-11 43.2 0.4 1.3e-07 31.3 0.2 2.7 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 KNZ78971.1 - 3.8e-09 36.0 6.2 0.49 10.6 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat AAA_22 PF13401.6 KNZ78971.1 - 1.5e-06 28.5 0.1 9e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ78971.1 - 4e-06 27.3 0.0 1.4e-05 25.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_8 PF13181.6 KNZ78971.1 - 5e-06 26.3 6.9 4.9 7.6 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ78971.1 - 8.8e-06 25.1 0.0 1.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KNZ78971.1 - 9.4e-05 22.9 4.9 11 7.2 0.2 5.9 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ78971.1 - 0.0014 18.3 5.0 1.5 8.8 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ78971.1 - 0.0015 19.2 5.6 0.055 14.1 0.3 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ78971.1 - 0.0023 17.8 2.5 5.2 7.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA PF00004.29 KNZ78971.1 - 0.0045 17.4 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_21 PF09976.9 KNZ78971.1 - 0.0072 16.1 2.1 0.084 12.6 0.3 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain AAA_7 PF12775.7 KNZ78971.1 - 0.0094 15.5 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TPR_6 PF13174.6 KNZ78971.1 - 0.012 16.2 4.6 1.7e+02 3.2 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ78971.1 - 0.035 14.0 3.5 2.3 8.2 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_24 PF13479.6 KNZ78971.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KNZ78971.1 - 0.042 13.8 0.0 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 KNZ78971.1 - 0.043 13.7 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Cohesin_load PF10345.9 KNZ78971.1 - 0.078 11.4 0.0 2.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Cohesin loading factor RPN7 PF10602.9 KNZ78971.1 - 0.11 12.2 0.0 0.74 9.5 0.0 2.4 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 KNZ78971.1 - 1.5 9.4 8.1 1.7 9.2 0.2 4.2 4 2 2 6 6 5 0 Tetratricopeptide repeat GerPC PF10737.9 KNZ78972.1 - 0.033 14.3 2.8 0.096 12.7 2.8 1.7 1 0 0 1 1 1 0 Spore germination protein GerPC OTT_1508_deam PF14441.6 KNZ78973.1 - 6.3e-09 35.7 0.3 1.4e-08 34.6 0.3 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DUF4443 PF14544.6 KNZ78973.1 - 0.0087 16.3 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) OTT_1508_deam PF14441.6 KNZ78974.1 - 4.6e-07 29.8 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_M36 PF02128.15 KNZ78975.1 - 3.1e-154 513.6 4.9 4.1e-154 513.2 4.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KNZ78975.1 - 7e-14 51.4 1.4 1.4e-13 50.4 1.4 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KNZ78975.1 - 0.0075 16.2 0.1 0.017 15.0 0.1 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Herpes_Helicase PF02689.14 KNZ78976.1 - 3.7e-06 25.2 0.0 4.2e-06 25.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ78976.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Pyr_redox_2 PF07992.14 KNZ78977.1 - 2.8e-52 177.8 0.1 9.2e-51 172.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 KNZ78977.1 - 6.3e-34 117.6 0.0 9.7e-19 67.8 0.0 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ78977.1 - 1.2e-30 106.5 0.0 9.4e-20 70.9 0.0 3.8 4 0 0 4 4 4 3 short chain dehydrogenase Pyr_redox PF00070.27 KNZ78977.1 - 8.4e-19 67.9 2.8 1.9e-13 50.8 0.0 4.1 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ78977.1 - 5e-16 58.8 3.6 6e-13 48.7 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase KR PF08659.10 KNZ78977.1 - 1.2e-06 28.5 0.1 3.1e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Thi4 PF01946.17 KNZ78977.1 - 2.6e-05 23.6 1.3 0.00012 21.4 0.0 2.5 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 KNZ78977.1 - 0.00035 19.4 2.0 0.22 10.2 0.1 3.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 KNZ78977.1 - 0.00075 19.2 0.2 0.01 15.4 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ78977.1 - 0.0008 18.6 0.4 0.013 14.6 0.1 2.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KNZ78977.1 - 0.0013 18.9 1.4 0.031 14.5 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 KNZ78977.1 - 0.0019 17.8 2.1 2 8.0 0.0 3.5 4 0 0 4 4 4 1 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KNZ78977.1 - 0.0036 16.6 4.8 0.068 12.4 0.0 3.4 3 1 1 4 4 4 1 FAD binding domain DUF1776 PF08643.10 KNZ78977.1 - 0.0061 16.0 0.0 0.069 12.5 0.0 2.0 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.6 KNZ78977.1 - 0.0078 16.6 0.2 0.39 11.2 0.0 3.1 3 1 0 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.22 KNZ78977.1 - 0.024 13.8 0.1 0.024 13.8 0.1 3.7 5 1 1 6 6 6 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 KNZ78977.1 - 0.026 14.8 0.3 0.17 12.1 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 KNZ78977.1 - 0.04 12.8 0.3 0.14 11.0 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase K_oxygenase PF13434.6 KNZ78977.1 - 0.043 13.0 0.0 1.2 8.2 0.0 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KNZ78977.1 - 0.05 13.0 0.0 0.05 13.0 0.0 2.4 3 0 0 3 3 2 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 KNZ78977.1 - 0.076 13.6 0.3 7.2 7.3 0.0 3.3 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KNZ78977.1 - 0.14 12.2 2.5 22 5.1 0.0 3.6 5 0 0 5 5 3 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KNZ78977.1 - 0.16 11.2 1.5 4.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3173 PF11372.8 KNZ78977.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) GDP_Man_Dehyd PF16363.5 KNZ78977.1 - 0.21 10.9 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2OG-FeII_Oxy PF03171.20 KNZ78978.1 - 9.8e-23 80.6 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KNZ78978.1 - 8.3e-20 71.7 0.0 2.4e-19 70.2 0.0 1.8 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal ELFV_dehydrog PF00208.21 KNZ78979.1 - 6.1e-56 189.8 0.0 9.3e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KNZ78979.1 - 4.9e-20 70.8 0.0 3.5e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase PTCB-BRCT PF12738.7 KNZ78980.1 - 8.3e-30 102.5 0.0 6e-14 51.7 0.0 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 KNZ78980.1 - 2e-19 69.7 0.1 6.8e-06 26.4 0.0 4.7 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KNZ78980.1 - 2.6e-07 30.9 0.0 0.22 12.0 0.0 4.2 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KNZ78980.1 - 0.0046 17.2 0.0 0.48 10.7 0.0 3.0 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain RNA_pol_A_bac PF01000.26 KNZ78981.1 - 6.1e-25 87.8 0.0 9.7e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KNZ78981.1 - 8.9e-21 73.1 0.0 1.5e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Glyco_hydro_16 PF00722.21 KNZ78982.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 16 O-FucT PF10250.9 KNZ78983.1 - 2.7e-08 33.9 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Cep57_MT_bd PF06657.13 KNZ78985.1 - 2.7e-24 85.4 0.0 2.7e-24 85.4 0.0 3.9 4 0 0 4 4 4 2 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KNZ78985.1 - 1.8e-10 40.7 4.7 1.8e-10 40.7 4.7 3.4 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 UPF0449 PF15136.6 KNZ78985.1 - 0.009 16.5 0.4 0.009 16.5 0.4 3.8 4 0 0 4 4 4 1 Uncharacterised protein family UPF0449 RIBIOP_C PF04950.12 KNZ78986.1 - 5.4e-94 314.9 5.3 1.5e-93 313.4 0.0 2.4 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KNZ78986.1 - 4.8e-29 100.3 0.0 1.6e-28 98.6 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.6 KNZ78986.1 - 5.1e-06 27.0 0.1 2.6e-05 24.7 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.27 KNZ78986.1 - 4.1e-05 23.2 0.2 0.016 14.8 0.0 2.8 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 KNZ78986.1 - 5.1e-05 23.6 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rtf2 PF04641.12 KNZ78986.1 - 5.2e-05 22.7 1.5 5.2e-05 22.7 1.5 2.8 3 0 0 3 3 3 1 Rtf2 RING-finger ABC_tran PF00005.27 KNZ78986.1 - 0.00019 21.9 2.6 0.0011 19.5 0.0 3.0 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 KNZ78986.1 - 0.00053 20.2 0.4 0.0021 18.2 0.0 2.3 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 KNZ78986.1 - 0.0011 19.0 0.1 0.0045 17.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 KNZ78986.1 - 0.0011 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KNZ78986.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 KNZ78986.1 - 0.0027 16.9 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 KNZ78986.1 - 0.0049 17.2 0.1 0.023 15.1 0.0 2.1 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 KNZ78986.1 - 0.0078 16.8 0.0 0.0078 16.8 0.0 3.3 3 0 0 3 3 1 1 AAA domain PduV-EutP PF10662.9 KNZ78986.1 - 0.0086 15.8 0.1 0.027 14.2 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 KNZ78986.1 - 0.014 15.2 0.1 0.37 10.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 KNZ78986.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KNZ78986.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KNZ78986.1 - 0.022 15.0 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KNZ78986.1 - 0.029 14.4 2.1 0.11 12.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 KNZ78986.1 - 0.032 14.6 0.1 0.094 13.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KNZ78986.1 - 0.035 14.0 0.2 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 KNZ78986.1 - 0.036 14.0 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 KNZ78986.1 - 0.05 13.3 1.6 0.094 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KNZ78986.1 - 0.051 14.0 0.0 0.051 14.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 KNZ78986.1 - 0.052 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 KNZ78986.1 - 0.071 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 KNZ78986.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 KNZ78986.1 - 0.11 12.4 3.5 0.18 11.7 0.0 2.5 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KNZ78986.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KNZ78986.1 - 0.52 10.1 0.0 0.52 10.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF3987 PF13148.6 KNZ78986.1 - 3.3 6.6 12.4 2.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Syntaxin_2 PF14523.6 KNZ78987.1 - 1.4e-20 73.6 2.1 1.4e-20 73.6 2.1 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 KNZ78987.1 - 2.6e-09 36.9 0.5 7.9e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 KNZ78987.1 - 3.2e-06 27.0 8.1 1e-05 25.3 8.1 1.8 1 1 0 1 1 1 1 Syntaxin T2SSF PF00482.23 KNZ78987.1 - 0.22 11.5 2.1 1 9.3 0.5 2.5 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Mit_KHE1 PF10173.9 KNZ78988.1 - 4.7e-55 186.6 0.0 6.3e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related BCD PF15461.6 KNZ78988.1 - 0.089 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase F-box-like PF12937.7 KNZ78989.1 - 3e-07 30.2 1.7 4e-07 29.8 0.3 2.0 2 0 0 2 2 2 1 F-box-like Cytokin_check_N PF10407.9 KNZ78989.1 - 0.032 14.2 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus MIF4G PF02854.19 KNZ78990.1 - 0.086 12.5 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 MIF4G domain Glyco_hydro_20 PF00728.22 KNZ78992.1 - 3.1e-77 260.3 0.0 4.6e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Peptidase_M16 PF00675.20 KNZ78992.1 - 2.1e-52 177.1 0.6 2.4e-51 173.6 0.1 2.5 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KNZ78992.1 - 1.9e-39 135.6 0.0 4.3e-37 127.9 0.0 2.9 3 0 0 3 3 3 1 Peptidase M16 inactive domain Glycohydro_20b2 PF14845.6 KNZ78992.1 - 0.067 13.9 0.0 0.16 12.6 0.0 1.7 1 0 0 1 1 1 0 beta-acetyl hexosaminidase like NLE PF08154.12 KNZ78993.1 - 6.1e-12 45.9 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 KNZ78993.1 - 1.4e-10 41.5 18.0 0.14 13.1 0.0 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat Adap_comp_sub PF00928.21 KNZ78994.1 - 1.3e-92 309.9 0.1 2.7e-92 308.9 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KNZ78994.1 - 3.1e-06 27.2 0.3 5.7e-06 26.3 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 KNZ78994.1 - 0.0053 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Scm3 PF10384.9 KNZ78995.1 - 2e-12 46.6 0.2 7.5e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 SMC_N PF02463.19 KNZ78996.1 - 4.5e-19 68.8 0.0 9.6e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNZ78996.1 - 4.1e-13 50.3 9.9 4.1e-13 50.3 9.9 5.8 3 2 1 4 4 4 1 AAA domain Spc7 PF08317.11 KNZ78996.1 - 0.00086 18.3 13.9 0.00086 18.3 13.9 4.9 2 2 2 5 5 5 2 Spc7 kinetochore protein AAA_29 PF13555.6 KNZ78996.1 - 0.084 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytochrom_B_N_2 PF13631.6 KNZ78997.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Cytochrome_B PF00033.19 KNZ78997.1 - 0.041 13.7 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b/b6/petB HSP70 PF00012.20 KNZ78998.1 - 7.5e-60 202.7 1.9 7e-59 199.5 0.3 2.4 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 KNZ78998.1 - 3e-11 42.7 0.1 7e-11 41.5 0.1 1.5 1 1 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 KNZ78998.1 - 0.013 14.5 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; PAN_4 PF14295.6 KNZ78999.1 - 2.5 8.1 9.1 2.8 7.9 0.2 4.0 3 1 1 4 4 4 0 PAN domain DDE_3 PF13358.6 KNZ79000.1 - 0.001 18.9 1.6 0.37 10.5 0.2 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease Cas9_b_hairpin PF17893.1 KNZ79000.1 - 0.16 11.8 0.0 0.45 10.3 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain ETF PF01012.21 KNZ79003.1 - 1e-37 129.8 0.1 1.3e-37 129.4 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SPESP1 PF15754.5 KNZ79004.1 - 0.63 9.2 4.6 1.9 7.6 4.6 1.7 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Nipped-B_C PF12830.7 KNZ79006.1 - 1.1e-52 178.8 4.0 1.1e-52 178.8 1.4 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KNZ79006.1 - 8.7e-11 41.9 1.3 8.7e-11 41.9 1.3 3.8 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KNZ79006.1 - 6.5e-05 22.9 0.9 2.9 8.4 0.0 4.8 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 KNZ79006.1 - 0.0051 16.9 0.2 0.041 13.9 0.1 2.7 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ79006.1 - 0.075 13.4 6.4 0.17 12.3 0.6 4.0 3 1 1 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 KNZ79006.1 - 3.2 8.4 12.1 5.9 7.5 0.2 5.7 5 1 1 6 6 6 0 HEAT-like repeat FANCI_S2 PF14676.6 KNZ79006.1 - 4 7.7 8.0 19 5.5 0.0 4.8 6 0 0 6 6 6 0 FANCI solenoid 2 RRM_1 PF00076.22 KNZ79007.1 - 6.6e-25 86.7 0.1 4.8e-13 48.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KNZ79007.1 - 3.7e-10 39.5 0.0 6.1e-07 29.1 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ79007.1 - 4.8e-08 32.7 0.0 3.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KNZ79007.1 - 0.0012 18.8 0.2 0.016 15.3 0.1 2.5 2 1 0 2 2 2 1 Limkain b1 RRM_3 PF08777.11 KNZ79007.1 - 0.054 13.5 0.1 0.41 10.7 0.0 2.2 2 1 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 KNZ79007.1 - 0.07 13.1 0.0 32 4.6 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 KNZ79007.1 - 0.12 12.6 3.9 6.1 7.0 0.0 3.7 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Mito_carr PF00153.27 KNZ79008.1 - 1.9e-69 229.6 0.9 2.6e-24 84.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KNZ79008.1 - 0.59 9.2 5.4 34 3.5 0.0 4.0 2 2 3 5 5 5 0 Gammaproteobacterial serine protease Transket_pyr PF02779.24 KNZ79009.1 - 4.1e-65 218.8 0.0 6.9e-65 218.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KNZ79009.1 - 3.2e-56 190.5 0.0 1.2e-55 188.6 0.0 1.9 2 1 0 2 2 2 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KNZ79009.1 - 1.6e-53 180.5 0.0 3e-53 179.6 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KNZ79009.1 - 9.8e-19 66.7 0.8 2e-18 65.7 0.8 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus EAP30 PF04157.16 KNZ79010.1 - 1e-33 116.6 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 KNZ79010.1 - 1.2e-20 73.4 0.0 2.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 KNZ79010.1 - 4e-05 22.8 3.4 0.14 11.5 1.0 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 KNZ79010.1 - 0.0032 16.8 4.7 0.02 14.3 0.4 2.6 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 KNZ79010.1 - 0.0083 16.1 2.8 0.1 12.6 3.4 2.2 1 1 1 2 2 2 2 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 KNZ79010.1 - 0.18 11.9 5.0 0.74 9.9 0.0 2.7 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger MFS_1 PF07690.16 KNZ79011.1 - 7.7e-13 48.1 40.5 7.9e-10 38.2 2.8 3.1 1 1 2 3 3 3 2 Major Facilitator Superfamily Pectinesterase PF01095.19 KNZ79012.1 - 2.4e-24 85.6 0.0 5.6e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Pectinesterase Bradykinin PF06753.12 KNZ79012.1 - 0.11 12.2 4.5 0.12 12.1 3.2 1.8 2 0 0 2 2 2 0 Bradykinin Retrotran_gag_2 PF14223.6 KNZ79013.1 - 3.4e-07 30.0 0.4 5.4e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ChaB PF06150.12 KNZ79013.1 - 0.02 15.5 0.2 0.043 14.4 0.2 1.5 1 0 0 1 1 1 0 ChaB MatE PF01554.18 KNZ79014.1 - 1.7e-06 27.8 14.6 0.00071 19.3 2.3 3.5 3 1 0 3 3 3 3 MatE DUF4134 PF13572.6 KNZ79015.1 - 0.056 13.7 0.2 2.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4134) Helitron_like_N PF14214.6 KNZ79016.1 - 6.3e-07 29.8 0.2 8.8e-07 29.3 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ79017.1 - 3.5e-107 358.7 0.0 4.4e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ79017.1 - 7.1e-08 32.4 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ79017.1 - 0.02 14.9 0.0 0.065 13.2 0.0 1.8 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ79017.1 - 0.028 14.8 0.0 0.12 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain UvrD_C_2 PF13538.6 KNZ79017.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KNZ79017.1 - 0.13 12.0 0.1 0.28 10.9 0.1 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ribonuc_L-PSP PF01042.21 KNZ79018.1 - 1.5e-32 112.2 0.0 1.7e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP gag-asp_proteas PF13975.6 KNZ79019.1 - 0.00045 20.7 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ79019.1 - 0.0027 18.3 0.0 0.0063 17.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH PF17917.1 KNZ79020.1 - 2.6e-06 27.6 0.0 3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ79020.1 - 0.00064 19.7 0.0 0.00098 19.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNase_H PF00075.24 KNZ79020.1 - 0.23 11.6 0.0 0.26 11.5 0.0 1.1 1 0 0 1 1 1 0 RNase H Zn_ribbon_17 PF17120.5 KNZ79021.1 - 4.7e-08 32.5 15.1 4.7e-08 32.5 15.1 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 KNZ79021.1 - 0.0015 19.3 0.3 0.0015 19.3 0.3 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat DZR PF12773.7 KNZ79021.1 - 0.5 10.4 15.4 1 9.4 15.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S10 PF00450.22 KNZ79022.1 - 1.6e-82 278.2 0.1 1.9e-79 268.0 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Abhydrolase_6 PF12697.7 KNZ79022.1 - 0.0086 16.7 0.2 2 8.9 0.0 2.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family GMC_oxred_N PF00732.19 KNZ79023.1 - 6.4e-52 176.8 0.0 9.8e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ79023.1 - 1.4e-27 97.0 0.0 6.9e-27 94.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase tRNA-synt_1c PF00749.21 KNZ79024.1 - 1.3e-76 257.5 0.0 3.2e-76 256.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-UBR PF02207.20 KNZ79025.1 - 5.8e-17 61.6 16.5 5.8e-17 61.6 16.5 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 KNZ79025.1 - 1.2e-12 47.4 0.4 2.9e-12 46.2 0.4 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 KNZ79025.1 - 0.0036 16.8 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL APH PF01636.23 KNZ79026.1 - 3.9e-15 56.4 0.4 1e-13 51.8 0.4 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ79026.1 - 0.0013 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ79026.1 - 0.0034 16.8 0.0 0.004 16.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KNZ79026.1 - 0.008 15.6 0.1 0.02 14.2 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ79026.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PCI PF01399.27 KNZ79027.1 - 1.9e-06 28.3 0.4 4.7e-06 27.0 0.5 1.7 1 1 0 1 1 1 1 PCI domain ATP-synt_E_2 PF08112.11 KNZ79027.1 - 0.0014 18.9 1.6 0.42 10.9 0.1 2.7 2 0 0 2 2 2 2 ATP synthase epsilon subunit Cortex-I_coil PF09304.10 KNZ79027.1 - 0.012 15.8 4.2 0.026 14.8 4.2 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil tRNA_bind_3 PF17176.4 KNZ79027.1 - 0.024 14.9 1.3 0.075 13.3 0.6 1.9 2 0 0 2 2 2 0 tRNA-binding domain DUF4404 PF14357.6 KNZ79027.1 - 0.084 13.5 3.1 0.31 11.7 3.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CSN7a_helixI PF18392.1 KNZ79027.1 - 0.084 12.8 0.9 0.17 11.8 0.9 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain zf-ANAPC11 PF12861.7 KNZ79028.1 - 1.2e-40 137.5 10.3 1.4e-40 137.3 10.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KNZ79028.1 - 1.2e-21 76.8 11.2 1.9e-21 76.1 11.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KNZ79028.1 - 0.00035 20.9 17.8 0.0025 18.1 16.4 2.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ79028.1 - 0.0068 16.2 4.4 0.0068 16.2 4.4 2.5 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ79028.1 - 0.045 13.8 10.1 0.1 12.6 10.1 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 KNZ79028.1 - 0.12 12.4 13.1 1.6 8.8 13.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 KNZ79028.1 - 0.18 11.7 13.9 0.97 9.4 13.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KNZ79028.1 - 3 7.7 13.7 15 5.4 13.7 2.1 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 KNZ79028.1 - 3.6 7.3 22.2 0.6 9.8 13.9 2.6 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PSP1 PF04468.12 KNZ79029.1 - 1.4e-30 105.4 2.3 2.3e-30 104.7 2.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DHC_N1 PF08385.12 KNZ79030.1 - 2.5e-124 416.0 7.7 1.8e-123 413.1 3.4 2.3 2 0 0 2 2 2 2 Dynein heavy chain, N-terminal region 1 ApoLp-III PF07464.11 KNZ79030.1 - 0.05 13.7 0.9 10 6.2 0.0 4.2 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) FAA_hydro_N_2 PF18288.1 KNZ79030.1 - 0.2 12.1 0.4 25 5.4 0.0 3.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 Herpes_UL82_83 PF05784.11 KNZ79031.1 - 0.16 10.8 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus RicinB_lectin_2 PF14200.6 KNZ79032.1 - 6.7e-22 78.0 2.9 7.8e-11 42.6 0.1 3.0 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 KNZ79032.1 - 2.1e-05 24.7 0.1 0.0078 16.5 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KNZ79033.1 - 9.7e-18 64.7 11.1 5.1e-10 39.9 1.4 2.9 1 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like Acid_PPase PF12689.7 KNZ79034.1 - 2.5e-53 180.4 0.0 2e-52 177.4 0.0 1.9 1 1 0 1 1 1 1 Acid Phosphatase Glyco_transf_15 PF01793.16 KNZ79035.1 - 2.4e-119 398.4 6.1 3e-119 398.1 6.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF3045 PF11243.8 KNZ79035.1 - 0.043 14.0 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) p450 PF00067.22 KNZ79036.1 - 3.8e-58 197.4 0.0 4.4e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Herpes_UL6 PF01763.16 KNZ79036.1 - 0.07 11.6 0.0 0.087 11.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like LodA_C PF18417.1 KNZ79036.1 - 0.17 11.6 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 L-lysine epsilon oxidase C-terminal domain DUF2160 PF09928.9 KNZ79037.1 - 0.0062 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Predicted small integral membrane protein (DUF2160) DCB PF16213.5 KNZ79039.1 - 1e-52 178.4 3.4 2.5e-52 177.1 1.0 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KNZ79039.1 - 1.5e-50 171.2 8.4 2.1e-50 170.7 3.2 3.3 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KNZ79039.1 - 2.7e-41 141.6 1.8 2.4e-24 85.6 0.7 3.3 2 2 0 2 2 2 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KNZ79039.1 - 1.8e-07 30.9 0.4 9.1e-05 22.2 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) RTP1_C1 PF10363.9 KNZ79039.1 - 0.0035 17.5 0.2 0.19 11.9 0.0 3.7 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CAP PF00188.26 KNZ79040.1 - 0.0072 17.2 0.3 0.013 16.3 0.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MeaB PF03308.16 KNZ79040.1 - 0.23 10.4 0.8 0.31 10.0 0.8 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NFACT-C PF11923.8 KNZ79041.1 - 0.15 12.0 0.5 0.33 10.9 0.0 1.8 2 0 0 2 2 2 0 NFACT protein C-terminal domain F-box PF00646.33 KNZ79042.1 - 8.1e-07 28.8 0.7 3.4e-06 26.8 0.7 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ79042.1 - 5.5e-05 23.0 0.4 0.00017 21.4 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KNZ79042.1 - 0.018 14.9 0.3 0.052 13.4 0.3 1.8 1 0 0 1 1 1 0 F-box EOS1 PF12326.8 KNZ79043.1 - 4.1e-32 111.5 10.8 2e-31 109.3 10.8 1.9 1 1 0 1 1 1 1 N-glycosylation protein F-box-like PF12937.7 KNZ79044.1 - 0.00017 21.4 2.0 0.00031 20.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like 2OG-FeII_Oxy_2 PF13532.6 KNZ79045.1 - 5.5e-26 92.0 0.0 7.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CENP-B_dimeris PF09026.10 KNZ79046.1 - 0.0055 17.1 6.6 0.0055 17.1 6.6 2.0 2 0 0 2 2 2 1 Centromere protein B dimerisation domain Mpp10 PF04006.12 KNZ79046.1 - 0.02 13.3 6.8 0.037 12.5 6.8 1.3 1 0 0 1 1 1 0 Mpp10 protein NOA36 PF06524.12 KNZ79046.1 - 0.033 13.5 11.7 0.074 12.4 11.7 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 KNZ79046.1 - 0.097 10.9 9.9 0.17 10.1 9.9 1.3 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KNZ79046.1 - 0.56 9.6 13.6 0.035 13.5 8.2 1.6 2 0 0 2 2 2 0 SDA1 RPN2_C PF18004.1 KNZ79046.1 - 0.63 9.9 7.0 5.9 6.8 6.7 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RXT2_N PF08595.11 KNZ79046.1 - 1.5 8.9 8.5 0.077 13.0 2.6 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal TFB6 PF17110.5 KNZ79046.1 - 3.5 7.3 5.2 6.9 6.4 5.2 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nucleo_P87 PF07267.11 KNZ79046.1 - 6.1 5.6 5.3 14 4.3 5.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.6 KNZ79046.1 - 7.4 7.0 13.6 11 6.5 10.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.12 KNZ79046.1 - 9.7 5.5 17.5 1.6e+02 1.5 17.5 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Piwi PF02171.17 KNZ79047.1 - 2.3e-82 276.6 0.0 3.2e-82 276.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KNZ79047.1 - 7.1e-22 78.5 0.0 1.3e-21 77.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KNZ79047.1 - 2.9e-15 55.7 0.8 9.2e-15 54.1 0.5 2.1 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 KNZ79047.1 - 2.1e-11 43.8 0.0 4.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KNZ79047.1 - 3.4e-09 36.9 0.4 4.1e-08 33.4 0.0 2.8 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoMid PF16487.5 KNZ79047.1 - 0.008 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Mid domain of argonaute DUF5388 PF17363.2 KNZ79047.1 - 0.13 12.5 0.0 4.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5388) AcetylCoA_hydro PF02550.15 KNZ79048.1 - 1.8e-42 145.6 0.0 2.5e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KNZ79048.1 - 3.2e-35 121.4 0.0 3.4e-28 98.5 0.0 2.3 2 0 0 2 2 2 2 Acetyl-CoA hydrolase/transferase C-terminal domain HMG_box PF00505.19 KNZ79050.1 - 7.3e-10 39.1 0.1 1.5e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ79050.1 - 0.0022 18.5 0.2 0.0056 17.2 0.0 1.7 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 KNZ79050.1 - 0.037 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 adh_short PF00106.25 KNZ79052.1 - 2.6e-16 59.7 0.0 9.2e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ79052.1 - 7.4e-13 48.6 0.0 9.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1128 PF06569.11 KNZ79052.1 - 0.025 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Eno-Rase_NADH_b PF12242.8 KNZ79052.1 - 0.1 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CBFD_NFYB_HMF PF00808.23 KNZ79053.1 - 0.0017 18.6 0.0 0.0049 17.1 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone STE PF02200.16 KNZ79054.1 - 2.8e-50 169.4 0.0 4.9e-50 168.6 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 KNZ79054.1 - 2.2e-10 40.4 9.7 8e-05 22.9 1.1 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ79054.1 - 9.4e-09 35.3 12.8 2.6e-08 33.9 3.7 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ79054.1 - 1.4e-08 34.8 7.6 0.00024 21.7 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNZ79054.1 - 2.5e-05 24.4 1.4 0.0091 16.3 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KNZ79054.1 - 0.0029 17.9 0.9 0.0086 16.3 0.9 1.8 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 KNZ79054.1 - 0.01 16.2 4.3 0.32 11.4 1.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KNZ79054.1 - 0.022 14.7 1.5 0.022 14.7 1.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 KNZ79054.1 - 0.065 13.5 0.9 0.14 12.4 0.9 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 KNZ79054.1 - 0.099 12.3 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 KNZ79054.1 - 0.1 13.1 5.9 3.8 8.0 0.6 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 KNZ79054.1 - 0.21 11.4 7.7 0.099 12.4 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KNZ79054.1 - 3.5 7.6 5.1 7.6 6.6 0.2 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Pkinase PF00069.25 KNZ79055.1 - 1.1e-33 116.7 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79055.1 - 4.5e-29 101.5 0.0 5.8e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79055.1 - 0.00045 19.6 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KNZ79055.1 - 0.002 17.7 0.0 0.004 16.8 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KNZ79055.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ79055.1 - 0.021 14.8 0.3 0.063 13.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ79055.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 KNZ79055.1 - 0.044 13.4 0.1 0.87 9.2 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1275 PF06912.11 KNZ79056.1 - 4.1e-21 75.8 5.6 5.1e-21 75.5 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2231 PF09990.9 KNZ79056.1 - 0.012 16.0 1.0 0.043 14.3 0.3 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Pkinase PF00069.25 KNZ79057.1 - 3.4e-14 52.9 0.0 4.6e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79057.1 - 0.016 14.5 0.0 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase SNARE_assoc PF09335.11 KNZ79058.1 - 4.7e-16 59.4 14.2 1.2e-15 58.1 8.6 2.7 3 0 0 3 3 3 2 SNARE associated Golgi protein LD_cluster2 PF18163.1 KNZ79060.1 - 0.12 11.8 2.3 0.41 10.1 2.3 1.9 1 0 0 1 1 1 0 SLOG cluster2 YbfN PF13982.6 KNZ79060.1 - 0.34 11.2 3.7 0.46 10.8 0.4 2.7 2 1 0 2 2 2 0 YbfN-like lipoprotein SlyX PF04102.12 KNZ79060.1 - 1.2 9.8 6.1 14 6.4 0.2 3.9 2 0 0 2 2 2 0 SlyX Pkinase PF00069.25 KNZ79061.1 - 3.1e-32 112.0 0.0 5.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79061.1 - 1.1e-31 110.0 0.0 2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Patatin PF01734.22 KNZ79061.1 - 8.3e-10 39.2 0.2 2.9e-08 34.1 0.2 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Kdo PF06293.14 KNZ79061.1 - 0.0073 15.7 0.0 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ79061.1 - 0.0087 16.0 0.2 0.019 14.9 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ79061.1 - 0.025 14.2 0.1 1.1 8.8 0.0 3.0 3 0 0 3 3 3 0 RIO1 family Kinase-like PF14531.6 KNZ79061.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ECH_2 PF16113.5 KNZ79063.1 - 0.044 13.3 0.2 0.074 12.5 0.2 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase RT_RNaseH PF17917.1 KNZ79064.1 - 8.1e-08 32.5 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ79064.1 - 0.0019 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RNase_H PF00075.24 KNZ79064.1 - 0.17 12.1 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 RNase H SNF2_N PF00176.23 KNZ79066.1 - 1e-65 221.8 0.1 2.2e-65 220.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KNZ79066.1 - 2e-38 130.9 0.5 2e-38 130.9 0.5 2.5 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KNZ79066.1 - 2.7e-32 111.8 0.3 2.7e-32 111.8 0.3 4.4 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 KNZ79066.1 - 1e-17 64.5 0.0 5.2e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ79066.1 - 8.7e-09 35.6 0.2 4.1e-08 33.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KNZ79066.1 - 4.4e-05 22.8 1.0 0.0001 21.6 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KNZ79066.1 - 0.0007 19.4 0.0 0.0025 17.6 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.6 KNZ79066.1 - 0.0008 19.5 0.0 0.018 15.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain DBINO PF13892.6 KNZ79066.1 - 0.0063 16.9 6.7 0.0063 16.9 6.7 3.9 4 0 0 4 4 4 1 DNA-binding domain MmoB_DmpM PF02406.17 KNZ79066.1 - 0.076 13.2 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 MmoB/DmpM family APG6_N PF17675.1 KNZ79071.1 - 0.47 11.0 7.5 0.69 10.5 7.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region APH PF01636.23 KNZ79074.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family MIX PF18529.1 KNZ79076.1 - 0.033 13.9 0.0 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial membrane-anchored proteins zf-CCHC PF00098.23 KNZ79080.1 - 0.00065 19.7 15.0 0.0017 18.3 4.1 3.6 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ79080.1 - 0.13 12.2 13.7 0.08 12.9 2.5 2.8 2 1 1 3 3 3 0 Zinc knuckle SNF2_N PF00176.23 KNZ79082.1 - 4.1e-67 226.4 0.3 4e-66 223.1 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ79082.1 - 4.5e-17 62.4 0.0 1.7e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ79082.1 - 2e-10 40.9 0.0 2.5e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KNZ79082.1 - 0.00039 19.7 0.1 0.0017 17.6 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KNZ79082.1 - 0.016 15.0 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF4939 PF16297.5 KNZ79083.1 - 0.012 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Retrotran_gag_2 PF14223.6 KNZ79086.1 - 4.3e-07 29.7 1.4 0.0017 18.0 0.2 2.8 1 1 2 3 3 3 2 gag-polypeptide of LTR copia-type UPF0524 PF15823.5 KNZ79087.1 - 0.027 13.9 1.3 0.033 13.6 1.3 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 RR_TM4-6 PF06459.12 KNZ79087.1 - 0.13 12.1 6.3 0.16 11.8 6.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 KNZ79087.1 - 0.21 11.0 12.6 0.23 10.9 12.6 1.1 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 KNZ79087.1 - 0.21 11.3 11.7 0.24 11.1 11.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 KNZ79087.1 - 0.28 9.3 16.0 0.3 9.3 16.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF789 PF05623.12 KNZ79087.1 - 0.42 10.3 3.5 0.46 10.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Myc_N PF01056.18 KNZ79087.1 - 0.91 9.4 7.6 1.3 8.9 7.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CSRNP_N PF16019.5 KNZ79087.1 - 1.6 8.6 5.2 2.1 8.2 5.2 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PPP4R2 PF09184.11 KNZ79087.1 - 1.7 8.2 14.7 2.1 7.9 14.7 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 KNZ79087.1 - 2.2 7.5 18.0 3 7.1 18.0 1.2 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.7 KNZ79087.1 - 2.4 6.2 3.7 2.8 5.9 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KNZ79087.1 - 2.6 6.2 9.4 3.2 5.9 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KNZ79087.1 - 3.3 6.4 7.4 3.5 6.3 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 KNZ79087.1 - 8 5.1 6.8 10 4.7 6.8 1.1 1 0 0 1 1 1 0 Presenilin NAD_binding_4 PF07993.12 KNZ79088.1 - 3.1e-13 49.5 0.0 5.4e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KNZ79088.1 - 0.0018 18.5 0.0 0.005 17.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Fip1 PF05182.13 KNZ79088.1 - 0.038 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Fip1 motif PLAC8 PF04749.17 KNZ79089.1 - 6.2e-17 62.4 0.8 8e-17 62.1 0.8 1.1 1 0 0 1 1 1 1 PLAC8 family DUF1349 PF07081.11 KNZ79090.1 - 5.5e-12 45.8 0.0 8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) WD40 PF00400.32 KNZ79094.1 - 0.00059 20.6 0.1 0.98 10.4 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_3 PF13570.6 KNZ79094.1 - 0.0032 17.9 0.1 55 4.4 0.0 4.7 5 0 0 5 5 5 0 PQQ-like domain AIF-MLS PF14962.6 KNZ79094.1 - 0.0036 17.3 0.3 0.0061 16.5 0.3 1.3 1 0 0 1 1 1 1 Mitochondria Localisation Sequence ANAPC4_WD40 PF12894.7 KNZ79094.1 - 0.0065 16.7 0.3 26 5.2 0.0 4.1 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 KNZ79094.1 - 0.016 14.8 0.0 0.15 11.6 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain ALG3 PF05208.13 KNZ79094.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 ALG3 protein PQQ PF01011.21 KNZ79094.1 - 0.064 13.2 0.0 3.7 7.6 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat Cnn_1N PF07989.11 KNZ79095.1 - 0.51 10.5 4.5 0.92 9.7 3.4 2.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 KNZ79095.1 - 4 7.7 15.9 0.36 11.0 8.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 RVP_2 PF08284.11 KNZ79096.1 - 0.0056 16.4 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease AAA_5 PF07728.14 KNZ79097.1 - 1.2e-64 216.4 0.0 2.1e-28 99.1 0.0 4.0 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ79097.1 - 0.014 15.8 0.1 2.7 8.4 0.0 3.4 3 1 1 4 4 4 0 AAA ATPase domain GNVR PF13807.6 KNZ79097.1 - 0.054 13.4 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase CbbQ_C PF08406.10 KNZ79097.1 - 0.14 12.4 0.0 28 5.1 0.0 2.6 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal DUF3886 PF13025.6 KNZ79097.1 - 0.22 11.7 2.8 0.62 10.3 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) NAD_binding_6 PF08030.12 KNZ79098.1 - 6.5e-36 123.8 0.0 1.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KNZ79098.1 - 1.8e-23 82.7 0.0 4e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KNZ79098.1 - 5.1e-17 62.2 6.8 5.1e-17 62.2 6.8 2.6 2 1 1 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KNZ79098.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Cation_ATPase_C PF00689.21 KNZ79098.1 - 0.84 9.3 10.1 0.22 11.2 6.6 1.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Glyco_hydro_28 PF00295.17 KNZ79099.1 - 4.8e-41 140.9 2.1 7.7e-41 140.2 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 HTH_29 PF13551.6 KNZ79100.1 - 0.00012 22.0 0.0 0.00025 21.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 KNZ79100.1 - 0.00014 21.6 0.1 0.00025 20.7 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 KNZ79100.1 - 0.0088 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4 PF04545.16 KNZ79100.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KNZ79100.1 - 0.031 14.2 0.0 0.084 12.9 0.0 1.7 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4_2 PF08281.12 KNZ79100.1 - 0.041 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_DeoR PF08220.12 KNZ79100.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.12 KNZ79100.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 HTH domain DUF1670 PF07900.11 KNZ79100.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) DUF1534 PF07551.11 KNZ79101.1 - 0.073 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1534) Zn_clus PF00172.18 KNZ79102.1 - 0.00041 20.4 11.3 0.00091 19.3 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.18 KNZ79102.1 - 0.019 15.2 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper Iso_dh PF00180.20 KNZ79103.1 - 8.3e-72 242.2 0.0 1e-71 241.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sod_Fe_C PF02777.18 KNZ79105.1 - 6.9e-36 122.5 0.1 1.2e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KNZ79105.1 - 3.7e-31 107.4 3.5 3.7e-31 107.4 3.5 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.6 KNZ79105.1 - 0.14 11.6 0.0 0.75 9.2 0.0 1.9 1 1 1 2 2 2 0 AsmA-like C-terminal region p450 PF00067.22 KNZ79106.1 - 4.9e-49 167.3 0.0 9.2e-48 163.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Actino_peptide PF14408.6 KNZ79108.1 - 0.33 11.1 0.1 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes p450 PF00067.22 KNZ79110.1 - 3.8e-47 161.1 0.0 5.1e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.14 KNZ79112.1 - 3e-23 82.5 0.0 4.2e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ79112.1 - 9.4e-13 48.5 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ79112.1 - 0.04 13.2 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KNZ79112.1 - 0.067 13.6 0.0 0.51 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KNZ79112.1 - 0.081 12.0 0.0 1 8.4 0.0 2.0 1 1 1 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 KNZ79112.1 - 0.085 12.4 0.4 1.3 8.6 0.0 2.3 1 1 1 3 3 3 0 FAD dependent oxidoreductase Mqo PF06039.15 KNZ79112.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Casc1_N PF15927.5 KNZ79113.1 - 2.9 7.5 12.2 6.1 6.5 12.2 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3801 PF12687.7 KNZ79113.1 - 3.3 7.7 11.3 0.26 11.3 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Velvet PF11754.8 KNZ79114.1 - 1e-39 137.0 0.4 3.1e-27 96.1 0.0 2.1 1 1 1 2 2 2 2 Velvet factor RVP_2 PF08284.11 KNZ79116.1 - 0.056 13.2 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Thaumatin PF00314.17 KNZ79118.1 - 7.2e-75 251.3 8.9 8.2e-75 251.1 8.9 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KNZ79118.1 - 0.098 11.9 0.7 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Beta-1,3-glucanase Glucan_synthase PF02364.15 KNZ79119.1 - 0 1265.8 0.0 0 1265.4 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KNZ79119.1 - 1.9e-42 144.7 0.1 5.2e-42 143.2 0.1 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Pkinase PF00069.25 KNZ79120.1 - 3.4e-17 62.7 0.1 3.8e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79120.1 - 3.2e-08 33.2 0.0 4.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79120.1 - 0.0012 18.2 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KNZ79120.1 - 0.2 10.4 0.0 0.71 8.6 0.0 1.8 1 1 0 1 1 1 0 Fungal protein kinase KORA PF16509.5 KNZ79122.1 - 0.039 14.2 0.1 0.061 13.6 0.1 1.4 1 1 1 2 2 2 0 TrfB plasmid transcriptional repressor PspB PF06667.12 KNZ79122.1 - 0.074 13.1 0.1 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Phage shock protein B Exonuc_V_gamma PF04257.14 KNZ79122.1 - 0.16 10.2 0.0 0.16 10.2 0.0 1.0 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit DAO PF01266.24 KNZ79123.1 - 4.6e-55 187.6 2.0 5.4e-55 187.4 2.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KNZ79123.1 - 1.3e-05 25.7 0.0 0.0082 16.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ79123.1 - 2.7e-05 24.3 0.2 5.4e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KNZ79123.1 - 4.6e-05 22.7 0.4 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KNZ79123.1 - 0.00018 20.9 0.1 0.03 13.6 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 KNZ79123.1 - 0.0016 17.8 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Thi4 PF01946.17 KNZ79123.1 - 0.014 14.7 0.5 0.025 13.8 0.5 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 KNZ79123.1 - 0.02 14.9 1.0 0.14 12.1 0.2 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 KNZ79123.1 - 0.021 13.7 0.3 0.056 12.3 0.6 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 KNZ79123.1 - 0.032 14.5 0.4 0.075 13.3 0.3 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain CLN3 PF02487.17 KNZ79124.1 - 3.1e-95 319.6 3.0 1.7e-48 165.7 0.5 2.2 2 0 0 2 2 2 2 CLN3 protein BAH PF01426.18 KNZ79126.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 BAH domain FoP_duplication PF13865.6 KNZ79126.1 - 0.68 10.5 26.6 0.065 13.8 10.5 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF5549 PF17703.1 KNZ79126.1 - 4.2 7.0 14.9 0.032 13.9 5.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5549) TB2_DP1_HVA22 PF03134.19 KNZ79127.1 - 4.8e-28 96.9 4.4 7.2e-28 96.3 4.4 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Gemini_mov PF01708.16 KNZ79127.1 - 0.16 11.8 0.3 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Geminivirus putative movement protein Helitron_like_N PF14214.6 KNZ79129.1 - 1.7e-17 64.3 0.3 2e-17 64.1 0.3 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ79131.1 - 1.8e-26 93.2 0.0 2.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 KNZ79131.1 - 0.0025 17.9 0.0 0.0028 17.7 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ79131.1 - 0.01 16.3 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 KNZ79131.1 - 0.014 15.2 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Sdh5 PF03937.16 KNZ79131.1 - 0.024 14.6 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase DUF2791 PF10923.8 KNZ79131.1 - 0.075 11.9 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Torsin PF06309.11 KNZ79131.1 - 0.092 12.8 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Viral_helicase1 PF01443.18 KNZ79131.1 - 0.15 11.8 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 KNZ79131.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 KNZ79131.1 - 0.16 11.5 0.1 0.18 11.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 KNZ79132.1 - 1.6e-31 109.9 0.1 2e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.6 KNZ79132.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain 4HPAD_g_N PF18671.1 KNZ79132.1 - 0.042 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Fungal_trans PF04082.18 KNZ79133.1 - 1.8e-14 53.4 0.0 3.8e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ79133.1 - 0.00011 22.2 13.8 0.00026 21.0 13.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLN3 PF02487.17 KNZ79134.1 - 3.8e-126 421.4 1.7 6.7e-126 420.5 1.7 1.4 1 1 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 KNZ79134.1 - 0.02 13.8 22.3 0.32 9.9 21.9 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily WD40 PF00400.32 KNZ79135.1 - 2.6e-31 107.2 15.1 6.7e-05 23.6 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KNZ79135.1 - 1e-05 25.3 0.1 2.7e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KNZ79135.1 - 2.2e-05 23.3 0.1 1.9 7.0 0.0 4.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KNZ79135.1 - 0.00037 20.7 0.0 7.4 7.0 0.0 4.4 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ79135.1 - 0.0025 17.2 0.0 0.038 13.3 0.0 2.3 2 1 0 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 KNZ79135.1 - 0.037 13.6 0.2 0.28 10.7 0.1 2.2 1 1 0 2 2 2 0 PQQ-like domain F-box PF00646.33 KNZ79135.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain RT_RNaseH PF17917.1 KNZ79136.1 - 0.051 13.9 0.0 0.054 13.8 0.0 1.0 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase K-box PF01486.17 KNZ79137.1 - 0.033 14.4 0.0 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 K-box region PP2C PF00481.21 KNZ79138.1 - 3.3e-31 108.8 0.0 4.6e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KNZ79138.1 - 3.4e-10 40.1 0.0 6.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) CAS_C PF12026.8 KNZ79138.1 - 0.051 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain STAG PF08514.11 KNZ79139.1 - 3.3e-38 130.1 3.3 3.7e-38 129.9 0.5 2.7 2 1 1 3 3 3 1 STAG domain HEAT_2 PF13646.6 KNZ79139.1 - 7.4e-08 32.7 0.0 1.1e-05 25.8 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KNZ79139.1 - 7.4e-06 25.8 0.1 4.8 7.7 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat GAS PF13851.6 KNZ79141.1 - 0.069 12.5 1.1 0.11 11.8 1.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4226 PF10774.9 KNZ79141.1 - 0.13 12.5 0.7 0.25 11.6 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Fungal_trans PF04082.18 KNZ79143.1 - 1.7e-06 27.2 0.0 7.3e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ79143.1 - 0.024 14.7 2.2 0.058 13.5 2.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP1_OBG PF01018.22 KNZ79144.1 - 1.6e-40 138.2 2.2 6.2e-29 100.6 1.1 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KNZ79144.1 - 1.7e-19 70.0 0.0 4e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ79144.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KNZ79144.1 - 0.0028 18.2 0.2 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KNZ79144.1 - 0.0033 17.0 0.0 0.034 13.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 KNZ79144.1 - 0.0034 17.0 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 KNZ79144.1 - 0.0083 16.2 0.0 0.5 10.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.27 KNZ79144.1 - 0.011 16.3 0.1 0.033 14.7 0.1 1.8 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 KNZ79144.1 - 0.019 14.4 0.1 0.99 8.8 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MeaB PF03308.16 KNZ79144.1 - 0.031 13.3 0.1 0.81 8.6 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 KNZ79144.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Pterin_bind PF00809.22 KNZ79145.1 - 2.3e-55 188.0 0.1 8.4e-55 186.1 0.1 1.8 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KNZ79145.1 - 2.7e-32 111.6 0.0 5.6e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Peptidase_S24 PF00717.23 KNZ79146.1 - 3.4e-08 33.3 0.0 5.3e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like RNase_H PF00075.24 KNZ79147.1 - 1.3e-05 25.4 0.1 2.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 RNase H FB_lectin PF07367.11 KNZ79148.1 - 6.4e-40 136.3 0.1 7.4e-40 136.1 0.1 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin NTP_transf_2 PF01909.23 KNZ79149.1 - 2e-07 31.2 0.0 5.7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 KNZ79149.1 - 3.8e-07 30.2 0.0 7.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 KNZ79149.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase AAA_7 PF12775.7 KNZ79150.1 - 0.047 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Syntaxin-6_N PF09177.11 KNZ79150.1 - 0.053 14.1 2.9 0.055 14.0 0.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF892 PF05974.12 KNZ79150.1 - 0.062 13.3 2.0 0.15 12.0 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Glyco_hydro_31 PF01055.26 KNZ79151.1 - 2.3e-10 40.2 0.1 2.7e-10 40.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KNZ79151.1 - 0.0011 19.3 0.0 0.0014 18.9 0.0 1.4 1 1 0 1 1 1 1 Galactose mutarotase-like THF_DHG_CYH PF00763.23 KNZ79151.1 - 0.11 12.7 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Zip PF02535.22 KNZ79152.1 - 2.7 7.1 4.2 3.1 6.9 4.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L28e PF01778.17 KNZ79153.1 - 1.5e-24 87.0 0.1 1.8e-24 86.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Polysacc_deac_1 PF01522.21 KNZ79154.1 - 0.00023 21.1 0.3 0.00083 19.2 0.3 2.0 1 1 0 1 1 1 1 Polysaccharide deacetylase gag_pre-integrs PF13976.6 KNZ79155.1 - 8.6e-07 28.7 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain alpha-hel2 PF14456.6 KNZ79155.1 - 0.08 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 TATR PF03430.13 KNZ79156.1 - 0.0036 15.8 0.0 0.0036 15.8 0.0 1.0 1 0 0 1 1 1 1 Trans-activating transcriptional regulator Helitron_like_N PF14214.6 KNZ79157.1 - 3.2e-61 206.9 0.1 4.4e-61 206.4 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Herpes_Helicase PF02689.14 KNZ79159.1 - 0.00021 19.4 0.0 0.00022 19.3 0.0 1.0 1 0 0 1 1 1 1 Helicase Latrophilin PF02354.16 KNZ79160.1 - 0.017 14.2 4.4 0.026 13.6 4.4 1.2 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region RRN3 PF05327.11 KNZ79160.1 - 0.11 11.1 3.3 0.12 10.9 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDP-OH_P_transf PF01066.21 KNZ79161.1 - 1e-17 64.6 0.1 1e-17 64.6 0.1 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_M17 PF00883.21 KNZ79162.1 - 1.4e-118 395.7 0.1 1.9e-118 395.3 0.1 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 KNZ79162.1 - 0.00021 21.2 0.2 0.00046 20.1 0.2 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain bZIP_1 PF00170.21 KNZ79163.1 - 8.4e-06 25.8 9.2 8.4e-06 25.8 9.2 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KNZ79163.1 - 1e-05 25.5 11.6 1e-05 25.5 11.6 1.6 2 0 0 2 2 2 1 Basic region leucine zipper Uds1 PF15456.6 KNZ79163.1 - 0.011 15.9 1.2 0.013 15.6 1.2 1.2 1 0 0 1 1 1 0 Up-regulated During Septation bZIP_Maf PF03131.17 KNZ79163.1 - 0.035 14.6 8.3 0.048 14.2 8.3 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor THP2 PF09432.10 KNZ79163.1 - 0.035 14.1 0.1 0.041 13.9 0.1 1.1 1 0 0 1 1 1 0 Tho complex subunit THP2 XkdW PF09636.10 KNZ79163.1 - 0.06 13.4 1.4 0.1 12.7 1.4 1.3 1 0 0 1 1 1 0 XkdW protein Tau95 PF09734.9 KNZ79163.1 - 0.091 13.6 2.1 0.12 13.1 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain COX5A PF02284.16 KNZ79164.1 - 2.7e-44 149.4 0.2 3.7e-44 148.9 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.9 KNZ79164.1 - 0.013 15.5 0.2 3.2 7.8 0.1 2.1 1 1 1 2 2 2 0 Tumour suppressor protein RNase_H PF00075.24 KNZ79165.1 - 8.9e-15 55.1 0.0 2.2e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 RNase H RdRP PF05183.12 KNZ79166.1 - 4.6e-05 22.3 0.0 6.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase CBM_21 PF03370.13 KNZ79167.1 - 1.6e-18 66.9 0.4 7.5e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KNZ79167.1 - 0.0029 18.2 5.8 0.73 10.5 2.6 2.8 3 0 0 3 3 3 2 Starch/carbohydrate-binding module (family 53) Ecl1 PF12855.7 KNZ79167.1 - 0.23 12.6 20.0 0.091 13.9 9.3 2.2 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins KRTAP PF11759.8 KNZ79167.1 - 3.9 8.1 18.1 1.7 9.2 4.2 2.5 2 0 0 2 2 2 0 Keratin-associated matrix Keratin_2_head PF16208.5 KNZ79167.1 - 7.4 6.7 22.8 6.9 6.8 3.8 2.8 2 1 1 3 3 3 0 Keratin type II head RVT_3 PF13456.6 KNZ79168.1 - 0.00092 19.0 0.0 0.0039 17.0 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like Vfa1 PF08432.10 KNZ79172.1 - 4e-31 108.8 17.9 1.2e-30 107.1 17.9 1.6 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.11 KNZ79172.1 - 0.033 12.3 2.0 0.037 12.1 2.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 KNZ79172.1 - 0.033 12.5 13.5 0.04 12.2 13.5 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 KNZ79172.1 - 0.13 11.1 5.3 0.13 11.0 5.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 KNZ79172.1 - 0.45 8.6 8.3 0.49 8.4 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 KNZ79172.1 - 8.8 5.0 5.0 11 4.7 5.0 1.2 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 KNZ79173.1 - 1.4e-81 268.3 1.4 1.9e-19 69.3 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KNZ79173.1 - 6.9e-26 90.2 0.7 2.9e-25 88.2 0.6 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 KNZ79173.1 - 9.8e-05 22.4 0.2 2.2 8.5 0.0 4.5 4 3 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 KNZ79173.1 - 0.00068 19.6 4.7 2.5 8.2 0.7 4.0 3 1 1 4 4 4 2 RNA binding motif OB_RNB PF08206.11 KNZ79173.1 - 0.0016 18.1 0.8 3.9 7.2 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KNZ79173.1 - 0.0026 17.7 0.1 6.4 6.9 0.0 3.9 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 KNZ79173.1 - 0.0096 16.4 5.6 0.25 11.9 1.0 2.9 3 0 0 3 3 3 1 Heat induced stress protein YflT Erf4 PF10256.9 KNZ79173.1 - 0.093 12.8 0.4 6.5 6.9 0.1 3.1 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF4407 PF14362.6 KNZ79173.1 - 2.5 7.4 6.7 6.1 6.1 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 KNZ79175.1 - 5.8e-20 70.9 0.2 2.3e-19 69.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KNZ79175.1 - 6.5e-19 67.9 0.6 1.1e-18 67.1 0.6 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.22 KNZ79176.1 - 7e-20 70.6 0.1 2.1e-19 69.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_H PF00075.24 KNZ79180.1 - 1.3e-16 61.0 1.3 1.9e-16 60.6 0.4 1.6 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 KNZ79180.1 - 0.00029 21.5 0.8 0.00074 20.2 0.8 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase MarR PF01047.22 KNZ79180.1 - 0.012 15.5 0.0 3.5 7.6 0.1 2.6 2 0 0 2 2 2 0 MarR family DUF2250 PF10007.9 KNZ79180.1 - 0.033 14.3 0.3 0.26 11.4 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) FliW PF02623.15 KNZ79184.1 - 0.093 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FliW protein RT_RNaseH PF17917.1 KNZ79185.1 - 8.6e-08 32.4 0.0 7.2e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ79185.1 - 0.00075 19.5 0.0 0.0093 16.0 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RRM_1 PF00076.22 KNZ79187.1 - 1.7e-40 136.6 0.3 2.5e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KNZ79187.1 - 7.1e-17 61.4 0.2 2e-16 59.9 0.0 1.8 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.11 KNZ79187.1 - 0.003 17.6 0.6 0.18 11.9 0.2 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 KNZ79187.1 - 0.018 14.9 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KNZ79187.1 - 0.068 13.2 0.0 3.1 7.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 KNZ79187.1 - 0.21 11.3 0.4 8.8 6.1 0.1 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain AMPK1_CBM PF16561.5 KNZ79189.1 - 4.3e-17 62.1 0.1 7.5e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Methyltransf_16 PF10294.9 KNZ79190.1 - 7.2e-43 146.3 0.0 9.7e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KNZ79190.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain COX15-CtaA PF02628.15 KNZ79191.1 - 5.1e-110 367.6 7.6 6.1e-110 367.3 7.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein TMEM72 PF16054.5 KNZ79191.1 - 0.1 12.3 0.4 0.27 10.9 0.4 1.7 1 0 0 1 1 1 0 Transmembrane protein family 72 BolA PF01722.18 KNZ79192.1 - 1.2e-10 41.5 0.0 3e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Chlam_OMP3 PF03503.13 KNZ79192.1 - 0.07 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 Stb3 PF10330.9 KNZ79192.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative Sin3 binding protein YIF1 PF03878.15 KNZ79194.1 - 1.8e-82 276.5 0.2 2.1e-82 276.2 0.2 1.0 1 0 0 1 1 1 1 YIF1 ADH_N PF08240.12 KNZ79196.1 - 2.8e-25 88.3 1.4 5.8e-25 87.3 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ79196.1 - 2.5e-19 69.5 0.2 5e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 KNZ79196.1 - 0.0014 18.0 0.5 0.0076 15.6 0.6 2.0 2 0 0 2 2 2 1 ThiF family AlaDh_PNT_C PF01262.21 KNZ79196.1 - 0.0026 17.1 0.1 0.0051 16.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KNZ79196.1 - 0.03 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1686 PF07937.11 KNZ79196.1 - 0.06 13.2 0.1 14 5.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) ACBP PF00887.19 KNZ79197.1 - 3.4e-23 81.7 0.1 5.2e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_M43 PF05572.13 KNZ79198.1 - 1.2e-32 112.9 1.6 9.3e-18 64.6 0.1 2.5 2 0 0 2 2 2 2 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KNZ79198.1 - 1e-09 38.8 2.3 3.5e-06 27.3 0.0 3.4 1 1 2 3 3 3 2 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KNZ79198.1 - 7.2e-08 33.0 0.3 0.00051 20.6 0.1 2.5 2 0 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 KNZ79198.1 - 9.4e-06 25.4 2.5 0.0014 18.3 0.0 2.8 2 1 0 2 2 2 2 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KNZ79198.1 - 0.00047 20.0 0.2 0.0069 16.2 0.1 2.5 2 1 0 2 2 2 1 Matrixin Peptidase_M57 PF12388.8 KNZ79198.1 - 0.0062 16.2 0.3 0.53 9.9 0.0 2.5 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase WT1 PF02165.15 KNZ79198.1 - 0.18 11.0 4.4 0.1 11.8 0.6 2.1 2 0 0 2 2 2 0 Wilm's tumour protein MRP-S34 PF16053.5 KNZ79199.1 - 4.7e-07 29.5 0.4 6.5e-07 29.1 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Glu-tRNAGln PF02686.15 KNZ79200.1 - 2.2e-08 34.3 0.0 3.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit dUTPase PF00692.19 KNZ79201.1 - 1.7e-43 147.3 0.0 2.1e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase THOC2_N PF16134.5 KNZ79202.1 - 4.2e-144 481.6 0.0 6.6e-144 480.9 0.0 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KNZ79202.1 - 3.8e-84 282.4 0.0 7.6e-84 281.5 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KNZ79202.1 - 1.4e-29 101.9 0.0 3.4e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit GTP_cyclohydroI PF01227.22 KNZ79203.1 - 2.4e-75 251.9 0.7 3e-75 251.6 0.7 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KNZ79203.1 - 0.0033 17.6 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.6 KNZ79203.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain ABC_tran PF00005.27 KNZ79204.1 - 7e-20 71.9 0.0 1.4e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KNZ79204.1 - 5.4e-05 23.2 0.1 0.00037 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 KNZ79204.1 - 0.0046 15.7 0.0 0.008 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 KNZ79204.1 - 0.012 15.0 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KNZ79204.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IMS PF00817.20 KNZ79208.1 - 1.2e-24 87.1 0.0 1.9e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KNZ79208.1 - 5.1e-15 56.2 0.0 4.8e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KNZ79208.1 - 1.2e-07 31.2 3.8 0.00016 21.2 1.7 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KNZ79208.1 - 0.0019 18.4 0.0 0.0059 16.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif CIA30 PF08547.12 KNZ79209.1 - 1.2e-24 87.2 0.0 1.6e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 KNZ79209.1 - 0.053 13.5 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain CBM_11 PF03425.13 KNZ79209.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Ras PF00071.22 KNZ79210.1 - 2.4e-52 176.8 0.2 2.9e-52 176.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ79210.1 - 1.7e-20 73.4 0.1 3.1e-20 72.6 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ79210.1 - 4e-10 39.4 0.0 4.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ79210.1 - 1.9e-05 24.3 0.0 3.9e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNZ79210.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ79210.1 - 0.0029 17.5 0.0 1.5 8.7 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KNZ79210.1 - 0.054 12.6 0.2 1.4 8.0 0.1 2.0 1 1 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 KNZ79210.1 - 0.25 11.1 2.4 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pyr_redox_2 PF07992.14 KNZ79211.1 - 7.9e-49 166.5 3.0 1e-48 166.1 3.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KNZ79211.1 - 1.1e-17 63.7 0.1 2.3e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KNZ79211.1 - 3.8e-09 37.0 3.2 5.4e-09 36.5 0.5 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KNZ79211.1 - 3.1e-07 30.9 0.0 7.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 KNZ79211.1 - 1.1e-06 28.5 0.0 3.2e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Pyr_redox_3 PF13738.6 KNZ79211.1 - 1.3e-06 27.9 0.3 1.8e-05 24.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KNZ79211.1 - 0.00031 20.0 0.0 0.47 9.5 0.0 2.4 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) APG17 PF04108.12 KNZ79213.1 - 4.3e-76 256.6 8.7 5.7e-76 256.2 8.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF2009 PF09418.10 KNZ79213.1 - 0.13 11.3 4.9 0.7 8.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2009) PI3K_P85_iSH2 PF16454.5 KNZ79213.1 - 0.16 11.6 15.1 0.34 10.5 6.2 3.7 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4201 PF13870.6 KNZ79213.1 - 0.27 10.9 6.1 0.63 9.8 3.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) DUF812 PF05667.11 KNZ79213.1 - 0.52 9.1 9.5 0.78 8.5 7.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Fez1 PF06818.15 KNZ79213.1 - 6.6 7.1 11.4 6.4 7.2 5.3 2.7 2 1 0 2 2 2 0 Fez1 ABC_membrane PF00664.23 KNZ79214.1 - 6.6e-67 226.0 27.7 1.8e-34 119.6 11.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ79214.1 - 8e-51 172.1 0.0 2.3e-29 102.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ79214.1 - 1.3e-08 34.6 2.5 0.0022 17.4 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNZ79214.1 - 0.00011 22.8 1.0 0.51 10.8 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 KNZ79214.1 - 0.00017 21.4 0.0 0.26 10.9 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 KNZ79214.1 - 0.00021 21.3 2.1 0.062 13.4 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KNZ79214.1 - 0.00027 20.3 0.9 0.29 10.4 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_21 PF13304.6 KNZ79214.1 - 0.00091 19.1 3.7 0.56 10.0 0.1 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KNZ79214.1 - 0.0015 18.9 0.3 0.99 9.8 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 KNZ79214.1 - 0.0016 18.2 0.0 0.58 9.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 KNZ79214.1 - 0.0029 17.5 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KNZ79214.1 - 0.005 16.6 0.5 0.69 9.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain TsaE PF02367.17 KNZ79214.1 - 0.017 15.1 1.0 0.36 10.8 0.1 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KNZ79214.1 - 0.02 14.4 0.9 3.6 7.1 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KNZ79214.1 - 0.024 14.2 0.1 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ79214.1 - 0.033 13.9 3.1 5.2 6.7 0.3 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 KNZ79214.1 - 0.038 14.0 0.8 6.6 6.8 0.1 2.5 2 0 0 2 2 2 0 Dynamin family ATP_bind_1 PF03029.17 KNZ79214.1 - 0.046 13.5 4.6 3.7 7.3 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 KNZ79214.1 - 0.053 13.4 2.0 0.13 12.1 0.3 2.2 2 0 0 2 2 2 0 NACHT domain MobB PF03205.14 KNZ79214.1 - 0.061 13.2 1.5 0.59 10.0 0.1 2.7 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 KNZ79214.1 - 0.083 12.1 1.8 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 KNZ79214.1 - 0.18 12.0 1.2 11 6.2 0.2 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Stevor PF17410.2 KNZ79214.1 - 0.21 11.1 1.9 0.38 10.2 1.9 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TrwB_AAD_bind PF10412.9 KNZ79214.1 - 0.24 10.3 3.8 1.3 7.8 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 KNZ79214.1 - 1.2 9.4 5.4 28 5.0 0.1 3.6 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 KNZ79214.1 - 1.5 9.3 3.1 19 5.7 0.1 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 KNZ79214.1 - 2.1 8.4 5.0 0.9 9.6 0.6 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MOZ_SAS PF01853.18 KNZ79215.1 - 6.2e-73 244.3 0.0 8.9e-73 243.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KNZ79215.1 - 9.7e-21 73.1 1.0 9.7e-21 73.1 1.0 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain PHD PF00628.29 KNZ79215.1 - 2.4e-16 59.4 22.3 1.6e-10 40.7 6.4 3.3 2 1 1 3 3 3 2 PHD-finger PHD_4 PF16866.5 KNZ79215.1 - 0.063 13.4 20.7 0.042 13.9 7.3 2.9 1 1 1 2 2 2 0 PHD-finger PHD_2 PF13831.6 KNZ79215.1 - 0.1 12.2 11.8 0.4 10.3 1.0 3.5 3 0 0 3 3 3 0 PHD-finger AT_hook PF02178.19 KNZ79215.1 - 0.63 10.1 9.6 0.59 10.2 3.3 3.3 2 0 0 2 2 2 0 AT hook motif RVP_2 PF08284.11 KNZ79218.1 - 0.00082 19.1 0.1 0.001 18.8 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KNZ79218.1 - 0.021 15.4 0.0 0.17 12.6 0.0 1.9 1 1 1 2 2 2 0 Aspartyl protease tRNA_lig_CPD PF08302.11 KNZ79219.1 - 0.011 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain SAP130_C PF16014.5 KNZ79220.1 - 9.3 5.2 10.5 0.43 9.6 4.1 1.7 1 1 1 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus p450 PF00067.22 KNZ79221.1 - 3.3e-67 227.2 0.1 7.1e-67 226.1 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KNZ79222.1 - 8.6e-48 163.0 0.0 1.5e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79222.1 - 4.6e-17 62.2 0.0 9.4e-17 61.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2370 PF10176.9 KNZ79224.1 - 5.5e-22 78.5 0.1 3.2e-16 59.7 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2370) UPF0061 PF02696.14 KNZ79225.1 - 8.1e-98 328.2 0.0 1.5e-97 327.3 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family CCDC53 PF10152.9 KNZ79226.1 - 0.087 13.2 0.5 0.14 12.6 0.3 1.4 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Adeno_PV PF03910.13 KNZ79226.1 - 7.8 5.1 6.3 12 4.5 6.3 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV GDA1_CD39 PF01150.17 KNZ79227.1 - 4e-17 62.0 0.0 4.8e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DcpS_C PF11969.8 KNZ79228.1 - 8.8e-29 100.3 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KNZ79228.1 - 1.2e-24 87.1 0.0 2.1e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal FAD_binding_4 PF01565.23 KNZ79229.1 - 8.6e-22 77.4 0.1 1.7e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KNZ79229.1 - 1.2e-06 28.5 0.0 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF4939 PF16297.5 KNZ79230.1 - 0.00099 19.0 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) p450 PF00067.22 KNZ79233.1 - 1.5e-48 165.7 0.0 9.3e-36 123.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HSP9_HSP12 PF04119.12 KNZ79234.1 - 8.2e-23 80.6 6.2 1.3e-22 79.9 6.2 1.3 1 0 0 1 1 1 1 Heat shock protein 9/12 DUF2263 PF10021.9 KNZ79235.1 - 4.4e-14 53.1 0.0 6.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) LRR_4 PF12799.7 KNZ79236.1 - 0.054 13.9 5.0 0.2 12.2 0.4 3.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Polysacc_synt_4 PF04669.13 KNZ79237.1 - 8.9e-19 67.8 1.5 6.2e-17 61.8 1.5 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis Meth_synt_1 PF08267.12 KNZ79237.1 - 0.0025 17.4 0.8 0.0029 17.2 0.8 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain DUF2491 PF10679.9 KNZ79237.1 - 0.013 14.7 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Myb_DNA-binding PF00249.31 KNZ79238.1 - 8.1e-08 32.3 0.3 1.5e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ79238.1 - 0.00046 20.4 0.2 0.0015 18.7 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain TIMELESS PF04821.14 KNZ79239.1 - 1e-79 267.7 0.3 1e-79 267.7 0.3 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 KNZ79239.1 - 2e-16 60.3 5.8 2e-16 60.3 5.8 3.6 3 1 1 4 4 4 1 Timeless protein C terminal region Rrn6 PF10214.9 KNZ79239.1 - 0.091 11.2 7.1 0.099 11.1 4.9 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor bZIP_1 PF00170.21 KNZ79240.1 - 3.9e-05 23.6 7.0 0.0055 16.8 3.4 2.2 2 0 0 2 2 2 2 bZIP transcription factor Shugoshin_N PF07558.11 KNZ79240.1 - 0.00099 18.9 2.1 0.0063 16.4 0.5 2.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 KNZ79240.1 - 0.018 15.1 14.9 0.024 14.7 3.3 2.7 3 0 0 3 3 3 0 Basic region leucine zipper TAL_FSA PF00923.19 KNZ79241.1 - 1.5e-30 106.6 0.0 1.8e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Hydrolase_6 PF13344.6 KNZ79242.1 - 1.3e-31 108.7 0.0 5.9e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ79242.1 - 1.7e-14 53.7 0.0 3.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KNZ79242.1 - 4e-10 40.3 0.0 6.1e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KNZ79242.1 - 1.7e-09 38.1 0.0 0.0001 22.5 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 KNZ79242.1 - 0.005 16.5 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Rox3 PF08633.10 KNZ79242.1 - 0.04 14.2 0.1 0.058 13.7 0.1 1.1 1 0 0 1 1 1 0 Rox3 mediator complex subunit Ribosomal_L7Ae PF01248.26 KNZ79242.1 - 0.067 12.9 0.1 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peripla_BP_4 PF13407.6 KNZ79242.1 - 0.097 12.2 0.0 2.6 7.6 0.0 2.1 1 1 1 2 2 2 0 Periplasmic binding protein domain Ribosomal_L34e PF01199.18 KNZ79243.1 - 5.6e-43 145.2 2.0 7.9e-43 144.7 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 KNZ79243.1 - 0.11 12.4 3.6 2.4 8.2 0.4 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain EndIII_4Fe-2S PF10576.9 KNZ79243.1 - 0.34 11.3 2.4 0.71 10.3 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III DUF3086 PF11285.8 KNZ79246.1 - 0.11 11.6 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) UL42 PF17638.2 KNZ79248.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.6 3 0 0 3 3 3 0 HCMV UL42 Tetraspanin PF00335.20 KNZ79249.1 - 0.15 11.7 1.0 0.37 10.5 0.3 1.8 2 0 0 2 2 2 0 Tetraspanin family TMEM208_SND2 PF05620.11 KNZ79249.1 - 0.88 9.3 3.4 3.8 7.3 0.2 2.6 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 p450 PF00067.22 KNZ79250.1 - 2.2e-69 234.4 0.0 4.5e-69 233.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 RVT_1 PF00078.27 KNZ79252.1 - 0.097 12.2 0.0 0.097 12.2 0.0 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 KNZ79253.1 - 0.02 14.7 0.4 0.029 14.2 0.4 1.2 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase DUF727 PF05303.12 KNZ79253.1 - 0.061 13.4 0.2 0.12 12.4 0.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF727) p450 PF00067.22 KNZ79255.1 - 1.4e-59 202.1 0.0 1.9e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 KNZ79256.1 - 9.3e-12 44.9 9.4 1.9e-11 43.9 9.4 1.5 1 0 0 1 1 1 1 CFEM domain Med21 PF11221.8 KNZ79256.1 - 0.2 11.9 0.7 0.28 11.4 0.7 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Ribosomal_L31e PF01198.19 KNZ79257.1 - 1.2e-35 121.6 0.1 1.5e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e CDI PF02234.19 KNZ79258.1 - 0.0042 17.2 0.9 2.9 8.1 0.0 2.6 2 0 0 2 2 2 2 Cyclin-dependent kinase inhibitor Apolipoprotein PF01442.18 KNZ79258.1 - 0.007 16.3 2.2 0.0081 16.1 0.8 1.8 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 KNZ79258.1 - 0.062 13.3 0.8 0.13 12.3 0.8 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cas_Csn2 PF09711.10 KNZ79258.1 - 0.57 9.8 5.8 2 8.0 5.4 2.0 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) p450 PF00067.22 KNZ79259.1 - 1.2e-63 215.4 0.0 3e-62 210.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Usp PF00582.26 KNZ79260.1 - 8.1e-11 42.6 0.0 1.4e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 Universal stress protein family Glyco_hydro_47 PF01532.20 KNZ79261.1 - 3e-130 435.2 0.0 3.3e-130 435.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MMR_HSR1 PF01926.23 KNZ79262.1 - 7.5e-14 51.8 0.0 1.8e-13 50.6 0.0 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KNZ79262.1 - 1.2e-09 38.4 0.6 6.1e-06 26.4 0.1 2.8 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KNZ79262.1 - 1.7e-08 34.0 0.0 2.3e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KNZ79262.1 - 7.6e-07 29.2 0.0 2e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase IIGP PF05049.13 KNZ79262.1 - 2.3e-06 26.9 0.0 5.3e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 KNZ79262.1 - 9.9e-06 25.0 0.0 2.1e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 KNZ79262.1 - 1.2e-05 25.8 0.0 3.6e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 ABC transporter GBP PF02263.19 KNZ79262.1 - 0.00024 20.4 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain FtsK_SpoIIIE PF01580.18 KNZ79262.1 - 0.00056 19.3 0.2 0.0097 15.3 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.17 KNZ79262.1 - 0.0014 18.7 0.1 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain Viral_helicase1 PF01443.18 KNZ79262.1 - 0.0015 18.3 0.0 0.0076 16.0 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 KNZ79262.1 - 0.0093 16.5 0.0 0.027 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 KNZ79262.1 - 0.012 16.1 1.3 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KNZ79262.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ79262.1 - 0.015 15.6 0.0 0.048 13.9 0.0 2.0 1 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 KNZ79262.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 KNZ79262.1 - 0.019 15.4 0.1 0.21 11.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 KNZ79262.1 - 0.023 14.5 0.9 3.7 7.3 0.1 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KNZ79262.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Torsin PF06309.11 KNZ79262.1 - 0.096 12.8 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Torsin AAA_33 PF13671.6 KNZ79262.1 - 0.098 12.8 0.6 0.24 11.5 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KNZ79262.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 KNZ79262.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 KaiC GTP_EFTU PF00009.27 KNZ79262.1 - 0.24 10.9 1.1 8.3 5.9 0.4 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 KNZ79262.1 - 0.26 11.5 2.1 0.77 10.0 0.9 2.5 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KNZ79263.1 - 3.1e-06 27.2 0.0 5.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KNZ79263.1 - 3.1e-05 24.1 0.1 0.22 11.6 0.0 2.6 1 1 2 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 KNZ79263.1 - 0.00028 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 KNZ79263.1 - 0.00029 20.2 0.0 0.0004 19.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 KNZ79263.1 - 0.023 14.0 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Septin GBP PF02263.19 KNZ79263.1 - 0.14 11.4 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Nup54 PF13874.6 KNZ79264.1 - 7e-37 126.6 6.1 9.8e-37 126.2 4.5 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KNZ79264.1 - 8.4e-24 84.2 104.2 1.8e-12 47.9 31.7 4.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nup54_C PF18437.1 KNZ79264.1 - 0.17 11.8 1.7 0.43 10.5 1.7 1.7 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain ZapB PF06005.12 KNZ79264.1 - 3.3 8.2 7.5 8.6 6.9 1.8 2.7 2 1 0 2 2 2 0 Cell division protein ZapB WD40 PF00400.32 KNZ79267.1 - 5.5e-24 84.0 2.7 0.00015 22.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79267.1 - 9.4e-15 54.7 0.0 6.5e-05 23.1 0.0 4.8 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ79267.1 - 2.7e-06 27.4 0.0 0.01 15.7 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KNZ79267.1 - 0.00071 18.7 0.0 1 8.3 0.0 2.7 3 0 0 3 3 3 2 Coatomer WD associated region PD40 PF07676.12 KNZ79267.1 - 0.0058 16.6 0.0 0.77 9.8 0.0 3.3 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KNZ79267.1 - 0.026 13.5 0.0 8.5 5.2 0.0 3.4 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KNZ79267.1 - 0.041 13.2 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain TFIIIC_delta PF12657.7 KNZ79267.1 - 0.079 12.9 0.2 17 5.2 0.0 2.7 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term BBS2_Mid PF14783.6 KNZ79267.1 - 0.086 12.9 0.1 2.6 8.1 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Srg PF02118.21 KNZ79269.1 - 0.00052 19.8 0.3 0.00052 19.8 0.3 2.1 1 1 1 2 2 2 1 Srg family chemoreceptor Ctr PF04145.15 KNZ79269.1 - 0.084 13.5 2.5 0.11 13.1 1.1 1.9 2 0 0 2 2 2 0 Ctr copper transporter family DPM3 PF08285.11 KNZ79269.1 - 2.1 8.6 7.7 53 4.1 2.9 3.3 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Fungal_trans PF04082.18 KNZ79271.1 - 1.4e-14 53.8 0.2 2.9e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ79271.1 - 2e-05 24.6 9.0 7.1e-05 22.8 9.0 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KNZ79273.1 - 1.5e-55 188.9 6.4 1.1e-27 97.1 1.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter AAA_16 PF13191.6 KNZ79273.1 - 3.7e-10 40.4 0.0 2.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 KNZ79273.1 - 1.6e-08 34.7 0.0 6.5e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 KNZ79273.1 - 5.3e-06 26.5 0.4 6.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KNZ79273.1 - 4.3e-05 23.8 0.1 0.00017 21.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KNZ79273.1 - 0.0013 19.2 0.1 0.016 15.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KNZ79273.1 - 0.034 14.5 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KNZ79273.1 - 0.045 14.3 0.2 0.27 11.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KNZ79273.1 - 0.091 12.8 0.1 2.6 8.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KNZ79273.1 - 0.097 13.0 0.1 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 KNZ79273.1 - 0.11 11.7 3.2 1.1 8.4 3.2 2.6 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.27 KNZ79273.1 - 0.13 12.8 0.1 1 9.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 KNZ79273.1 - 0.14 11.1 1.1 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NifW PF03206.14 KNZ79273.1 - 0.51 10.9 3.9 1.5 9.4 3.9 1.9 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Pkinase_Tyr PF07714.17 KNZ79274.1 - 7.7e-24 84.4 0.0 1.1e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ79274.1 - 2.9e-20 72.7 0.0 5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TRI9 PF08195.11 KNZ79274.1 - 0.05 13.5 0.2 3.3 7.7 0.2 2.5 2 0 0 2 2 2 0 TRI9 protein Kinase-like PF14531.6 KNZ79274.1 - 0.058 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FF PF01846.19 KNZ79274.1 - 0.12 12.6 0.2 0.81 9.9 0.1 2.2 1 1 1 2 2 2 0 FF domain NmrA PF05368.13 KNZ79275.1 - 5.8e-30 104.6 0.0 1.4e-29 103.4 0.0 1.5 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ79275.1 - 7.1e-14 52.1 0.0 3.3e-13 49.9 0.0 2.1 1 1 1 2 2 2 1 NAD(P)H-binding KR PF08659.10 KNZ79275.1 - 3.2e-06 27.2 0.0 1.7e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KNZ79275.1 - 6.2e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KNZ79275.1 - 0.00047 19.6 0.0 0.0027 17.2 0.0 2.1 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KNZ79275.1 - 0.033 13.7 0.0 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KNZ79275.1 - 0.043 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KNZ79275.1 - 0.15 11.2 0.0 0.69 9.0 0.0 2.1 3 0 0 3 3 3 0 Male sterility protein ATP-synt PF00231.19 KNZ79276.1 - 7.3e-76 255.5 1.6 8.4e-76 255.3 1.6 1.0 1 0 0 1 1 1 1 ATP synthase MFS_1 PF07690.16 KNZ79277.1 - 7.1e-11 41.6 45.5 4.7e-07 29.1 29.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_H_Exchanger PF00999.21 KNZ79278.1 - 4.3e-50 170.6 37.6 4.3e-50 170.6 37.6 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family ADH_zinc_N PF00107.26 KNZ79279.1 - 4.8e-18 65.4 0.0 7.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ79279.1 - 9.6e-11 41.5 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KNZ79279.1 - 4.1e-06 26.4 0.1 7.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KNZ79279.1 - 0.002 19.2 0.0 0.0039 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KNZ79279.1 - 0.089 12.7 0.1 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated B12-binding_2 PF02607.17 KNZ79279.1 - 0.13 12.7 0.2 1.1 9.7 0.1 2.1 2 0 0 2 2 2 0 B12 binding domain 2-Hacid_dh_C PF02826.19 KNZ79279.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 KNZ79280.1 - 3.6e-27 94.4 0.2 5.5e-27 93.8 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ79280.1 - 1.3e-17 63.9 0.0 2.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KNZ79280.1 - 3.6e-05 23.3 0.2 8.8e-05 22.1 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KNZ79280.1 - 0.0011 20.0 0.1 0.0022 19.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 KNZ79280.1 - 0.06 13.6 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_N_assoc PF13823.6 KNZ79280.1 - 0.12 12.3 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Trs65 PF12735.7 KNZ79281.1 - 4.1e-25 88.9 0.0 4.3e-14 52.7 0.1 3.3 2 1 1 3 3 3 3 TRAPP trafficking subunit Trs65 Ank_2 PF12796.7 KNZ79282.1 - 2.6e-15 56.8 1.4 2e-11 44.3 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ79282.1 - 2.3e-12 46.9 0.6 0.0049 17.2 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ79282.1 - 2.2e-10 39.9 0.1 0.072 13.7 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 KNZ79282.1 - 4.8e-10 39.8 1.0 3.1e-06 27.6 0.2 4.0 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 KNZ79282.1 - 1.3e-05 25.4 1.4 1.5 9.4 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeat MARVEL PF01284.23 KNZ79282.1 - 0.0034 17.4 5.9 0.0034 17.4 5.9 1.9 2 0 0 2 2 2 1 Membrane-associating domain MMR_HSR1 PF01926.23 KNZ79283.1 - 9.9e-11 41.7 0.0 2.4e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KNZ79283.1 - 2.3e-09 36.9 0.0 6.8e-09 35.4 0.0 1.7 1 1 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 KNZ79283.1 - 7e-09 35.8 0.1 3.6e-08 33.5 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase Septin PF00735.18 KNZ79283.1 - 1.1e-07 31.4 0.0 2.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 Septin Dynamin_N PF00350.23 KNZ79283.1 - 4.3e-06 26.9 2.8 0.013 15.6 0.2 2.8 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 KNZ79283.1 - 1.6e-05 25.5 0.1 4.2e-05 24.1 0.0 1.8 2 1 0 2 2 2 1 ABC transporter GBP PF02263.19 KNZ79283.1 - 1.9e-05 24.1 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_23 PF13476.6 KNZ79283.1 - 0.0039 17.7 0.8 0.98 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain IIGP PF05049.13 KNZ79283.1 - 0.004 16.3 0.1 0.0076 15.4 0.0 1.4 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 KNZ79283.1 - 0.0051 16.5 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ79283.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KNZ79283.1 - 0.023 13.9 0.0 2.2 7.4 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KNZ79283.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 KNZ79283.1 - 0.065 12.8 0.1 0.42 10.1 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B Rad17 PF03215.15 KNZ79283.1 - 0.07 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain DUF5475 PF17569.2 KNZ79283.1 - 0.079 13.3 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5475) MKLP1_Arf_bdg PF16540.5 KNZ79283.1 - 0.084 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 AAA_30 PF13604.6 KNZ79283.1 - 0.087 12.5 0.7 1.5 8.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KNZ79283.1 - 0.095 12.4 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ79283.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KNZ79283.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain LepA_C PF06421.12 KNZ79283.1 - 0.12 12.6 0.4 0.22 11.7 0.4 1.5 1 1 0 1 1 1 0 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.27 KNZ79283.1 - 0.23 11.0 2.4 1.4 8.4 0.2 2.9 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KNZ79283.1 - 0.28 10.9 1.8 1 9.1 0.1 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF1732 PF08340.11 KNZ79283.1 - 0.44 10.6 4.1 0.19 11.7 1.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF1732) Rtf2 PF04641.12 KNZ79284.1 - 6.8e-09 35.5 9.1 1e-05 25.0 1.3 2.4 2 1 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 KNZ79284.1 - 1e-08 34.9 18.5 2e-05 24.4 9.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 KNZ79284.1 - 1.3e-06 28.4 1.3 1.3e-06 28.4 1.3 2.6 2 1 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 KNZ79284.1 - 4e-06 26.6 19.6 0.0056 16.5 10.4 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ79284.1 - 5e-06 26.4 15.2 0.00034 20.6 0.8 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 KNZ79284.1 - 9.7e-06 25.4 21.0 3.6e-05 23.6 9.6 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 KNZ79284.1 - 1.9e-05 24.9 18.2 0.015 15.6 10.1 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 KNZ79284.1 - 0.0002 21.2 18.9 0.033 14.1 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KNZ79284.1 - 0.00067 19.5 20.7 0.13 12.1 10.6 3.3 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zinc-ribbons_6 PF07191.12 KNZ79284.1 - 0.097 12.7 14.8 0.83 9.7 1.4 2.6 2 1 0 2 2 2 0 zinc-ribbons zf-C3HC4_4 PF15227.6 KNZ79284.1 - 0.11 12.7 16.2 0.14 12.4 1.1 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 KNZ79284.1 - 1.8 8.8 12.2 5.6 7.2 4.6 3.0 2 1 0 2 2 2 0 FYVE zinc finger TFIIS_C PF01096.18 KNZ79284.1 - 2.2 8.2 0.0 2.2 8.2 0.0 3.8 5 0 0 5 5 5 0 Transcription factor S-II (TFIIS) LsmAD PF06741.13 KNZ79284.1 - 2.3 8.8 6.8 0.58 10.7 1.0 2.2 2 0 0 2 2 2 0 LsmAD domain MMR_HSR1 PF01926.23 KNZ79285.1 - 4.5e-10 39.6 0.0 9.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ79285.1 - 6.6e-07 29.4 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KNZ79285.1 - 2.9e-06 27.5 0.3 0.077 13.1 0.0 2.8 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.27 KNZ79285.1 - 1.6e-05 25.5 0.0 3.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.16 KNZ79285.1 - 8.7e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 1 0 1 1 1 1 AIG1 family Septin PF00735.18 KNZ79285.1 - 0.00025 20.4 0.0 0.00071 18.9 0.0 1.8 2 0 0 2 2 2 1 Septin IIGP PF05049.13 KNZ79285.1 - 0.0024 17.0 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KNZ79285.1 - 0.003 17.8 0.0 0.067 13.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KNZ79285.1 - 0.04 13.7 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GBP PF02263.19 KNZ79285.1 - 0.067 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain GBP PF02263.19 KNZ79286.1 - 3.7e-05 23.1 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 KNZ79286.1 - 0.0027 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1 PF01926.23 KNZ79287.1 - 7e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KNZ79287.1 - 1.9e-08 33.9 0.1 3.2e-08 33.1 0.1 1.5 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KNZ79287.1 - 1.2e-06 28.6 0.1 2.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 KNZ79287.1 - 2.2e-06 27.8 0.3 0.06 13.4 0.1 2.5 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 KNZ79287.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 KNZ79287.1 - 0.00021 21.8 0.1 0.0004 20.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 KNZ79287.1 - 0.0033 17.9 0.9 0.01 16.4 0.9 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 KNZ79287.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B IIGP PF05049.13 KNZ79287.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 KNZ79287.1 - 0.019 15.3 0.1 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KNZ79287.1 - 0.039 13.3 0.2 0.25 10.7 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.6 KNZ79287.1 - 0.043 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spore_IV_A PF09547.10 KNZ79287.1 - 0.058 12.3 0.2 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Stage IV sporulation protein A (spore_IV_A) T2SSE PF00437.20 KNZ79287.1 - 0.081 12.0 0.2 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 KNZ79287.1 - 0.13 12.3 0.1 0.9 9.6 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain cobW PF02492.19 KNZ79287.1 - 0.17 11.5 0.2 0.39 10.3 0.2 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 KNZ79287.1 - 0.22 11.0 1.0 9 5.8 0.2 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FliT PF05400.13 KNZ79287.1 - 6.8 7.6 7.8 11 6.9 0.4 2.7 2 1 1 3 3 2 0 Flagellar protein FliT MMR_HSR1 PF01926.23 KNZ79288.1 - 1.2e-09 38.3 1.0 7.3e-09 35.7 0.1 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase AIG1 PF04548.16 KNZ79288.1 - 2.4e-06 27.0 0.0 4.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KNZ79288.1 - 2.4e-06 27.7 3.0 0.0051 16.9 0.1 3.3 3 1 1 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 KNZ79288.1 - 3.9e-05 23.6 0.0 9.4e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 KNZ79288.1 - 0.00032 20.1 0.0 0.00073 18.9 0.0 1.6 1 0 0 1 1 1 1 Septin ABC_tran PF00005.27 KNZ79288.1 - 0.0011 19.5 0.1 0.0065 17.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 KNZ79288.1 - 0.018 15.3 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 KNZ79288.1 - 0.023 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein GBP PF02263.19 KNZ79288.1 - 0.024 13.9 0.0 0.076 12.3 0.0 1.7 1 1 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_18 PF13238.6 KNZ79288.1 - 0.11 13.1 0.1 0.8 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KNZ79288.1 - 0.13 12.7 0.1 0.79 10.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Aldo_ket_red PF00248.21 KNZ79289.1 - 1.9e-66 224.2 0.0 2.4e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease_2 PF13520.6 KNZ79290.1 - 3.4e-43 148.0 46.0 5.9e-43 147.3 44.9 1.7 1 1 1 2 2 2 2 Amino acid permease Yip1 PF04893.17 KNZ79291.1 - 2e-06 27.6 25.7 4.2e-06 26.6 25.4 1.6 1 1 0 1 1 1 1 Yip1 domain AIM5 PF17050.5 KNZ79292.1 - 1.2e-06 29.3 0.2 1.7e-06 28.7 0.2 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 DLH PF01738.18 KNZ79293.1 - 2.6e-19 69.6 0.0 3.1e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 KNZ79293.1 - 0.21 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Pkinase PF00069.25 KNZ79294.1 - 1.2e-30 106.7 0.0 2.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79294.1 - 1.3e-28 100.0 0.0 1.2e-27 96.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ79294.1 - 0.027 14.4 0.1 0.069 13.1 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79294.1 - 0.032 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ79294.1 - 0.2 10.9 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PAD PF03068.15 KNZ79295.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) DUF1033 PF06279.11 KNZ79295.1 - 7 6.9 7.0 0.63 10.2 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1033) EFG_II PF14492.6 KNZ79296.1 - 0.15 12.2 0.3 0.6 10.2 0.1 1.9 2 0 0 2 2 2 0 Elongation Factor G, domain II Phos_pyr_kin PF08543.12 KNZ79298.1 - 2.3e-89 299.0 0.5 3.1e-89 298.6 0.5 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KNZ79298.1 - 2.5e-39 135.3 0.0 3.8e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KNZ79298.1 - 3.4e-08 33.2 0.0 5.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 KNZ79298.1 - 0.00024 20.5 4.9 0.00088 18.7 0.3 3.0 2 1 0 2 2 2 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 KNZ79298.1 - 0.0044 16.5 1.6 0.017 14.6 1.6 2.1 1 1 0 1 1 1 1 Carbohydrate kinase HhH-GPD PF00730.25 KNZ79299.1 - 6.3e-20 71.6 0.0 9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KNZ79299.1 - 3.8e-08 32.8 0.0 9.6e-08 31.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 KNZ79299.1 - 0.01 16.4 1.3 0.83 10.3 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix domain GPI-anchored PF10342.9 KNZ79301.1 - 0.0071 17.1 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Adeno_E3_CR2 PF02439.15 KNZ79301.1 - 0.019 14.7 0.9 0.047 13.5 0.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 KilA-N PF04383.13 KNZ79304.1 - 0.0021 17.9 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 KilA-N domain Mannosyl_trans2 PF04188.13 KNZ79306.1 - 0.022 14.1 9.1 0.026 13.8 9.1 1.1 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) APH PF01636.23 KNZ79307.1 - 8.6e-11 42.2 0.2 2.9e-10 40.5 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ79307.1 - 2.3e-05 24.1 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ79307.1 - 0.07 12.5 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain SNF2_N PF00176.23 KNZ79310.1 - 3.6e-27 95.0 0.0 6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ79310.1 - 1.7e-14 54.1 0.0 4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ79310.1 - 1.1e-06 28.8 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNZ79310.1 - 0.0028 16.9 0.1 0.0047 16.2 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 KNZ79312.1 - 2.4e-15 56.7 0.1 2.4e-15 56.7 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Golgin_A5 PF09787.9 KNZ79312.1 - 0.039 13.4 4.0 0.062 12.8 4.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Gluconate_2-dh3 PF13618.6 KNZ79312.1 - 0.061 13.6 0.8 0.13 12.5 0.8 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DASH_Spc34 PF08657.10 KNZ79312.1 - 0.24 11.2 4.6 1.3 8.8 2.7 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 GrpE PF01025.19 KNZ79312.1 - 0.54 9.9 4.5 1 9.0 4.5 1.4 1 0 0 1 1 1 0 GrpE Vir_act_alpha_C PF10400.9 KNZ79312.1 - 5.2 7.8 6.7 65 4.3 6.7 2.3 1 1 0 1 1 1 0 Virulence activator alpha C-term N1221 PF07923.13 KNZ79314.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 N1221-like protein Chromo PF00385.24 KNZ79316.1 - 2.8e-09 36.7 0.1 6.5e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 KNZ79316.1 - 0.005 16.9 0.0 6 7.0 0.0 2.9 2 1 1 3 3 3 2 Chromo shadow domain Mtf2_C PF14061.6 KNZ79316.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 NARP1 PF12569.8 KNZ79317.1 - 0.54 9.1 2.7 0.83 8.5 2.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sigma70_r2 PF04542.14 KNZ79318.1 - 0.11 12.2 0.1 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-70 region 2 PNTB_4TM PF12769.7 KNZ79319.1 - 0.078 13.5 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch RdRP PF05183.12 KNZ79320.1 - 3.9e-171 570.7 0.0 5.6e-171 570.1 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Myb_DNA-bind_2 PF08914.11 KNZ79321.1 - 3.1e-08 33.7 0.4 1.4e-07 31.6 0.4 2.1 1 1 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 KNZ79321.1 - 2.8e-05 24.4 0.0 5.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Gtr1_RagA PF04670.12 KNZ79322.1 - 3.3e-83 278.6 0.0 5e-83 278.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 KNZ79322.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ79322.1 - 8e-06 26.1 0.0 1.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KNZ79322.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KNZ79322.1 - 0.00049 19.6 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Viral_helicase1 PF01443.18 KNZ79322.1 - 0.032 14.0 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MACPF PF01823.19 KNZ79322.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 MAC/Perforin domain DMRL_synthase PF00885.19 KNZ79323.1 - 2.2e-56 189.6 0.0 2.7e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.12 KNZ79324.1 - 1.3e-26 93.2 0.3 8.5e-26 90.6 0.3 2.4 2 0 0 2 2 2 1 SRP40, C-terminal domain Hydrolase_4 PF12146.8 KNZ79325.1 - 1.2e-10 41.1 0.0 2.7e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ79325.1 - 1.6e-09 37.8 0.0 9.5e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ79325.1 - 1.6e-07 32.2 0.0 2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KNZ79325.1 - 0.017 14.9 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 KNZ79325.1 - 0.031 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 KNZ79325.1 - 0.22 11.2 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) ATP_bind_3 PF01171.20 KNZ79327.1 - 1.6e-43 148.6 0.0 3e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Glyco_transf_22 PF03901.17 KNZ79328.1 - 2.3e-73 247.8 29.3 3e-73 247.5 29.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IDO PF01231.18 KNZ79328.1 - 0.093 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase Pyr_redox_2 PF07992.14 KNZ79329.1 - 1.2e-44 152.7 0.1 1.9e-44 152.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 KNZ79329.1 - 2.5e-11 42.3 4.7 2.1e-05 23.7 1.8 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KNZ79329.1 - 6.9e-09 34.9 2.7 0.00059 19.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain Pyr_redox PF00070.27 KNZ79329.1 - 4e-08 33.7 6.2 3.4e-07 30.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 KNZ79329.1 - 3.7e-07 30.5 6.8 2.2e-05 24.8 2.9 2.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KNZ79329.1 - 2.6e-06 26.7 2.5 0.0069 15.8 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 KNZ79329.1 - 3.5e-06 26.8 2.7 0.033 14.0 1.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair K_oxygenase PF13434.6 KNZ79329.1 - 0.0028 16.9 0.0 0.67 9.0 0.0 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KNZ79329.1 - 0.0063 15.8 3.0 5.3 6.2 2.5 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KNZ79329.1 - 0.09 13.2 0.0 1.2 9.6 0.0 2.6 1 1 0 1 1 1 0 Putative NAD(P)-binding YTH PF04146.15 KNZ79330.1 - 2.4e-38 131.7 0.0 2.4e-38 131.7 0.0 3.0 3 0 0 3 3 3 1 YT521-B-like domain Inhibitor_I36 PF03995.13 KNZ79330.1 - 0.2 11.6 3.1 0.65 10.0 3.1 1.9 1 0 0 1 1 1 0 Peptidase inhibitor family I36 Herpes_LMP2 PF07415.11 KNZ79330.1 - 2.5 6.8 5.5 4.3 6.0 5.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein KH_1 PF00013.29 KNZ79331.1 - 7.6e-43 144.2 9.0 6.1e-15 54.8 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KNZ79331.1 - 3.7e-15 55.5 8.1 3.4e-05 23.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KNZ79331.1 - 8.2e-06 25.6 2.6 0.086 12.7 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 KNZ79331.1 - 0.00027 21.0 5.6 0.78 9.9 0.1 3.6 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 KNZ79331.1 - 0.078 13.0 0.0 4.2 7.4 0.0 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain Ebola_NP PF05505.12 KNZ79331.1 - 0.17 10.1 0.0 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Brix PF04427.18 KNZ79332.1 - 7.1e-34 117.6 0.0 1.1e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain DUF4572 PF15139.6 KNZ79333.1 - 0.097 12.6 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) Syntaxin-6_N PF09177.11 KNZ79334.1 - 0.28 11.8 15.1 0.051 14.1 5.6 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SOGA PF11365.8 KNZ79334.1 - 1.1 10.4 11.9 5.4 8.2 0.7 2.7 2 1 0 2 2 2 0 Protein SOGA APG6_N PF17675.1 KNZ79334.1 - 6 7.4 22.5 1.4 9.5 6.9 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region TRAM_LAG1_CLN8 PF03798.16 KNZ79336.1 - 1.3e-21 77.3 13.2 6.9e-21 74.9 13.2 1.9 1 1 0 1 1 1 1 TLC domain Vps54 PF07928.12 KNZ79337.1 - 3.4e-52 176.4 2.3 6.9e-52 175.4 1.1 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2451 PF10474.9 KNZ79337.1 - 0.00011 22.1 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 KNZ79337.1 - 0.00051 19.4 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex zf-MYND PF01753.18 KNZ79338.1 - 0.033 14.3 0.2 0.079 13.1 0.2 1.6 1 0 0 1 1 1 0 MYND finger LNP1 PF15419.6 KNZ79338.1 - 0.18 12.0 0.1 0.18 12.0 0.1 2.8 4 0 0 4 4 4 0 Leukemia NUP98 fusion partner 1 Ecl1 PF12855.7 KNZ79338.1 - 1.2 10.2 39.2 5.3e+02 1.7 39.2 2.6 1 1 0 1 1 1 0 ECL1/2/3 zinc binding proteins WD40 PF00400.32 KNZ79339.1 - 6.5e-30 102.7 17.2 3e-07 31.0 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79339.1 - 1.7e-10 41.0 4.1 0.0035 17.6 0.2 5.1 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Elongin_A PF06881.11 KNZ79340.1 - 6.4e-25 87.7 1.1 1.1e-24 87.0 1.1 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A AAA_lid_6 PF17866.1 KNZ79340.1 - 0.23 11.7 3.4 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA lid domain cwf18 PF08315.12 KNZ79341.1 - 1.2e-31 110.2 12.2 2.8e-31 109.0 12.2 1.6 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor ELH PF02323.15 KNZ79341.1 - 0.008 15.6 1.8 0.013 14.9 1.8 1.5 1 1 0 1 1 1 1 Egg-laying hormone precursor Ferritin PF00210.24 KNZ79341.1 - 0.066 13.1 0.8 0.09 12.7 0.8 1.2 1 0 0 1 1 1 0 Ferritin-like domain SIR4_SID PF16991.5 KNZ79341.1 - 0.081 13.0 0.2 0.1 12.6 0.2 1.3 1 0 0 1 1 1 0 Sir4 SID domain HTH_37 PF13744.6 KNZ79342.1 - 0.24 11.4 0.7 0.45 10.5 0.7 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Alanine_zipper PF11839.8 KNZ79343.1 - 0.029 14.7 3.6 0.044 14.2 3.6 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein LPP PF04728.13 KNZ79343.1 - 0.88 10.0 4.1 0.77 10.2 0.6 2.1 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Pheromone PF08015.11 KNZ79343.1 - 2.6 9.1 11.8 2.6 9.2 7.7 2.3 1 1 1 2 2 2 0 Fungal mating-type pheromone tRNA-synt_1 PF00133.22 KNZ79345.1 - 1.4e-27 96.3 0.0 1.8e-16 59.5 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KNZ79345.1 - 5.6e-13 49.1 0.3 1.6e-12 47.6 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KNZ79345.1 - 4.8e-09 35.4 0.0 3.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KNZ79345.1 - 1e-08 34.9 0.0 1.4e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain ArfGap PF01412.18 KNZ79346.1 - 1.9e-42 144.0 0.1 2.9e-42 143.5 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UNC-93 PF05978.16 KNZ79347.1 - 1.1e-13 51.2 6.9 1.1e-13 51.2 6.9 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KNZ79347.1 - 1.5e-11 43.8 14.8 1.5e-11 43.8 14.8 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 KNZ79348.1 - 2.4e-15 56.4 31.6 2.4e-15 56.4 31.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KNZ79348.1 - 9.8e-12 44.9 7.4 9.8e-12 44.9 7.4 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Pkinase PF00069.25 KNZ79349.1 - 5.6e-70 235.7 0.0 6.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79349.1 - 1.5e-40 139.1 0.0 1.8e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79349.1 - 3.5e-07 29.8 0.0 1.8e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KNZ79349.1 - 0.022 14.7 3.1 1.1 9.1 0.2 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79349.1 - 0.043 13.2 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KNZ79349.1 - 0.12 11.9 0.1 0.64 9.6 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2244 PF10003.9 KNZ79350.1 - 0.74 9.5 11.6 0.72 9.5 0.5 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) AF-4 PF05110.13 KNZ79351.1 - 4.8 5.1 7.9 6.4 4.7 7.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Pkinase PF00069.25 KNZ79352.1 - 4.9e-61 206.4 0.0 1.4e-60 204.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79352.1 - 1.8e-29 102.8 0.0 4e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79352.1 - 0.00025 20.4 0.1 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KNZ79352.1 - 0.0013 18.7 0.2 0.042 13.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79352.1 - 0.0049 16.3 0.9 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ79352.1 - 0.019 13.9 0.0 0.041 12.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KNZ79352.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_C PF00433.24 KNZ79352.1 - 0.11 13.2 0.1 0.23 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Spindle_Spc25 PF08234.12 KNZ79353.1 - 1.2e-18 67.0 0.0 2.6e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 KNZ79353.1 - 0.00097 18.1 5.4 0.0013 17.7 5.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.11 KNZ79353.1 - 0.0017 17.4 4.0 0.0021 17.0 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) NCKAP5 PF15246.6 KNZ79353.1 - 0.03 13.9 0.9 0.057 13.0 0.0 1.7 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein YlqD PF11068.8 KNZ79353.1 - 0.36 11.2 4.0 0.56 10.6 4.0 1.2 1 0 0 1 1 1 0 YlqD protein DivIC PF04977.15 KNZ79353.1 - 0.64 9.8 4.9 0.2 11.4 1.7 1.7 2 0 0 2 2 2 0 Septum formation initiator GrpE PF01025.19 KNZ79353.1 - 0.81 9.3 6.8 0.24 11.1 2.9 1.9 1 1 1 2 2 2 0 GrpE Atg14 PF10186.9 KNZ79353.1 - 0.84 8.7 9.1 1.1 8.3 9.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 KNZ79353.1 - 1.3 9.4 11.9 4.7 7.6 11.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 KNZ79353.1 - 1.7 8.5 5.9 2.5 7.9 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) APG6_N PF17675.1 KNZ79353.1 - 3 8.4 13.3 5.9 7.4 13.3 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region TFIIS_C PF01096.18 KNZ79354.1 - 6.8e-18 64.2 6.2 7.5e-17 60.9 0.6 3.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KNZ79354.1 - 1.2e-09 37.9 1.6 6e-07 29.2 0.1 2.8 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 KNZ79354.1 - 0.0001 22.3 7.5 0.0024 17.9 0.2 2.7 2 1 1 3 3 3 1 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 KNZ79354.1 - 0.00047 20.1 7.2 0.01 15.8 0.7 3.0 2 1 1 3 3 3 1 Transposase zinc-ribbon domain IBR PF01485.21 KNZ79354.1 - 0.0024 18.1 4.7 0.16 12.3 0.0 2.5 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 KNZ79354.1 - 0.0027 17.1 14.7 0.16 11.4 2.4 4.0 3 1 1 4 4 4 2 zinc-ribbon domain Baculo_LEF5_C PF11792.8 KNZ79354.1 - 0.008 15.8 2.8 0.012 15.3 0.4 2.3 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zf-RING_7 PF02591.15 KNZ79354.1 - 0.01 16.0 7.5 1.9 8.7 0.1 3.9 4 0 0 4 4 4 1 C4-type zinc ribbon domain zf-C4_Topoisom PF01396.19 KNZ79354.1 - 0.012 15.4 8.5 1.4 8.8 1.6 4.0 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger DUF2387 PF09526.10 KNZ79354.1 - 0.014 15.6 2.4 0.16 12.1 0.1 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Lar_restr_allev PF14354.6 KNZ79354.1 - 0.014 15.8 3.8 2.6 8.5 0.2 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.6 KNZ79354.1 - 0.028 14.3 11.1 3.2 7.8 1.8 4.0 3 1 1 4 4 4 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 KNZ79354.1 - 0.033 13.9 9.9 4.9 6.9 2.7 3.9 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit Mu-like_Com PF10122.9 KNZ79354.1 - 0.035 13.5 6.0 2 7.9 0.0 3.0 2 1 1 3 3 3 0 Mu-like prophage protein Com SBP PF03110.14 KNZ79354.1 - 0.042 14.2 0.6 0.098 13.0 0.0 1.9 2 1 0 2 2 1 0 SBP domain PHD PF00628.29 KNZ79354.1 - 0.05 13.5 7.2 1.7 8.6 1.1 2.6 2 1 1 3 3 3 0 PHD-finger HypA PF01155.19 KNZ79354.1 - 0.052 13.6 4.5 1.2 9.2 0.1 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 KNZ79354.1 - 0.067 13.3 10.9 11 6.3 0.0 4.1 3 1 1 4 4 4 0 Zinc ribbon domain DUF3268 PF11672.8 KNZ79354.1 - 0.091 13.1 0.6 0.091 13.1 0.6 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain OrfB_Zn_ribbon PF07282.11 KNZ79354.1 - 0.13 12.2 7.0 2.5 8.1 0.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_9 PF14369.6 KNZ79354.1 - 0.14 12.4 6.8 41 4.5 2.5 4.0 3 1 1 4 4 4 0 zinc-ribbon zinc_ribbon_2 PF13240.6 KNZ79354.1 - 0.15 11.8 15.3 1.9 8.3 0.3 3.7 4 0 0 4 4 3 0 zinc-ribbon domain zf_UBZ PF18439.1 KNZ79354.1 - 0.18 11.4 7.8 9.4 5.9 0.1 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Nudix_N_2 PF14803.6 KNZ79354.1 - 0.26 11.2 13.8 1.3 9.0 3.8 3.8 2 2 0 2 2 2 0 Nudix N-terminal zinc_ribbon_10 PF10058.9 KNZ79354.1 - 0.28 10.9 5.6 12 5.8 0.0 3.8 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein Methyltransf_13 PF08421.11 KNZ79354.1 - 0.51 10.6 5.1 24 5.3 0.1 3.5 4 0 0 4 4 3 0 Putative zinc binding domain DNA_ligase_ZBD PF03119.16 KNZ79354.1 - 0.54 10.3 5.2 7.1 6.7 0.3 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain CpXC PF14353.6 KNZ79354.1 - 0.57 10.2 9.1 7.5 6.6 0.8 3.4 2 1 1 3 3 3 0 CpXC protein zf-ACC PF17848.1 KNZ79354.1 - 0.58 10.3 10.0 10 6.3 0.2 4.1 4 0 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain PhnA_Zn_Ribbon PF08274.12 KNZ79354.1 - 0.69 9.9 9.9 4.3 7.4 1.3 3.6 3 1 0 3 3 3 0 PhnA Zinc-Ribbon TF_Zn_Ribbon PF08271.12 KNZ79354.1 - 0.7 9.4 10.9 0.36 10.4 1.0 3.0 2 1 0 2 2 2 0 TFIIB zinc-binding XAF1_C PF18608.1 KNZ79354.1 - 1.2 8.8 8.0 5.7 6.6 1.1 3.6 4 0 0 4 4 4 0 XIAP-associated factor 1 C-terminal domain zinc_ribbon_15 PF17032.5 KNZ79354.1 - 1.6 9.5 10.4 4 8.3 0.7 3.1 1 1 1 3 3 3 0 zinc-ribbon family UPF0547 PF10571.9 KNZ79354.1 - 1.6 8.9 14.6 6 7.0 0.2 3.7 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-LITAF-like PF10601.9 KNZ79354.1 - 1.8 8.9 9.7 8.2 6.8 0.7 4.0 4 1 0 4 4 4 0 LITAF-like zinc ribbon domain Ribosomal_S27e PF01667.17 KNZ79354.1 - 1.9 8.2 9.9 1.9 8.3 2.5 3.3 3 1 0 3 3 2 0 Ribosomal protein S27 zf-TFIIB PF13453.6 KNZ79354.1 - 2.1 7.7 9.5 8.8 5.8 1.2 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger zf-NADH-PPase PF09297.11 KNZ79354.1 - 2.6 7.8 17.5 0.67 9.7 4.5 3.6 3 1 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain DUF35_N PF12172.8 KNZ79354.1 - 2.6 8.0 10.8 12 5.8 0.1 4.2 5 0 0 5 5 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RecR PF02132.15 KNZ79354.1 - 2.7 7.6 9.1 20 4.8 0.1 3.5 2 2 1 3 3 3 0 RecR protein zf-FPG_IleRS PF06827.14 KNZ79354.1 - 3.5 7.6 10.3 6.7 6.7 0.0 3.4 3 1 1 4 4 3 0 Zinc finger found in FPG and IleRS Prok-RING_1 PF14446.6 KNZ79354.1 - 4 7.4 14.7 0.95 9.4 5.0 3.3 3 1 1 4 4 3 0 Prokaryotic RING finger family 1 TB2_DP1_HVA22 PF03134.19 KNZ79355.1 - 4.9e-26 90.5 7.7 4.9e-26 90.5 7.7 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family ABM PF03992.16 KNZ79356.1 - 1e-06 28.8 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase PDZ_5 PF17817.1 KNZ79357.1 - 0.061 13.6 0.2 0.64 10.3 0.0 2.8 2 0 0 2 2 2 0 PDZ domain VHS PF00790.19 KNZ79358.1 - 1.7e-40 138.1 1.2 1.1e-39 135.5 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KNZ79358.1 - 2.6e-16 59.5 6.7 4.5e-16 58.7 6.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 KNZ79358.1 - 2.8e-05 23.7 12.3 0.008 16.0 3.3 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 KNZ79358.1 - 0.02 15.1 3.3 0.046 14.0 3.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Zn-ribbon_8 PF09723.10 KNZ79358.1 - 0.5 10.5 2.1 0.58 10.3 0.5 2.0 1 1 1 2 2 2 0 Zinc ribbon domain DZR PF12773.7 KNZ79358.1 - 0.7 10.0 7.5 3 7.9 3.7 2.3 1 1 1 2 2 2 0 Double zinc ribbon Joubert PF15392.6 KNZ79358.1 - 5 6.8 16.8 0.49 10.1 12.0 1.8 2 0 0 2 2 2 0 Joubert syndrome-associated Vps35 PF03635.17 KNZ79360.1 - 1.1e-303 1009.4 2.5 1.3e-303 1009.1 2.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 KNZ79360.1 - 0.09 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP Phospholip_B PF04916.13 KNZ79360.1 - 0.096 11.2 0.2 0.98 7.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase B Cyt-b5 PF00173.28 KNZ79361.1 - 7.4e-20 70.9 0.4 1.5e-19 69.9 0.4 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KNZ79361.1 - 8.4e-13 48.8 17.6 1.8e-12 47.7 17.6 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily POT1PC PF16686.5 KNZ79362.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Glyco_transf_90 PF05686.12 KNZ79363.1 - 1.8e-09 37.0 0.1 2.3e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 gag-asp_proteas PF13975.6 KNZ79364.1 - 8.6e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ79364.1 - 1.2e-06 29.1 0.0 1.8e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ79364.1 - 0.004 17.0 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Vps26 PF03643.15 KNZ79366.1 - 1.6e-09 37.2 0.3 3.5e-06 26.2 0.2 2.1 1 1 1 2 2 2 2 Vacuolar protein sorting-associated protein 26 PGK PF00162.19 KNZ79367.1 - 1.2e-143 478.7 0.2 1.3e-143 478.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Pheromone PF08015.11 KNZ79368.1 - 4 8.5 9.2 0.98 10.5 0.2 3.2 4 0 0 4 4 4 0 Fungal mating-type pheromone Atg14 PF10186.9 KNZ79368.1 - 5.8 5.9 9.2 7.8 5.5 9.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SDA1 PF05285.12 KNZ79370.1 - 2.5e-85 287.0 40.9 9.6e-46 156.8 6.6 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.12 KNZ79370.1 - 1.4e-24 86.2 0.1 3.3e-23 81.8 0.0 2.6 2 0 0 2 2 2 1 NUC130/3NT domain NUDIX PF00293.28 KNZ79371.1 - 1e-14 54.7 0.0 4.3e-14 52.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DUF2790 PF10976.8 KNZ79371.1 - 0.086 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) PNK3P PF08645.11 KNZ79372.1 - 2.5e-45 154.1 0.0 4.8e-45 153.2 0.0 1.5 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KNZ79372.1 - 4.3e-17 62.6 0.0 2.4e-08 34.3 0.0 2.7 2 1 1 3 3 3 2 AAA domain LNS2 PF08235.13 KNZ79372.1 - 0.063 12.7 0.0 0.089 12.3 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) MMR_HSR1 PF01926.23 KNZ79372.1 - 0.084 13.0 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase GalP_UDP_transf PF01087.22 KNZ79373.1 - 1.6e-60 204.7 0.0 2.5e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KNZ79373.1 - 2.2e-46 157.6 0.0 5.2e-46 156.4 0.0 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DcpS_C PF11969.8 KNZ79373.1 - 0.0095 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KNZ79373.1 - 0.011 16.4 0.4 0.074 13.8 0.3 2.3 2 1 0 2 2 2 0 HIT domain PRP38 PF03371.15 KNZ79374.1 - 1.8e-49 167.9 0.3 2.3e-49 167.6 0.3 1.1 1 0 0 1 1 1 1 PRP38 family Ribosomal_L27A PF00828.19 KNZ79375.1 - 1.6e-28 99.9 0.0 2.3e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GMC_oxred_N PF00732.19 KNZ79376.1 - 9.9e-63 212.2 0.0 1.3e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ79376.1 - 2.6e-34 118.8 0.0 4.2e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ79376.1 - 0.00012 22.3 0.8 0.00061 20.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ79376.1 - 0.0014 17.8 0.1 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KNZ79376.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KNZ79376.1 - 0.046 13.0 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ79376.1 - 0.057 12.5 0.2 0.41 9.7 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KNZ79376.1 - 0.08 12.5 0.1 0.25 10.9 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase IPPT PF01715.17 KNZ79377.1 - 1.2e-62 211.7 0.0 3.2e-62 210.3 0.0 1.6 1 1 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 KNZ79377.1 - 0.00093 19.7 0.1 0.038 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KNZ79377.1 - 0.013 15.6 0.1 1.7 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 KNZ79377.1 - 0.017 14.7 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KNZ79377.1 - 0.032 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 KNZ79377.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 KNZ79379.1 - 7.8e-41 139.6 0.0 1.9e-40 138.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.9 KNZ79379.1 - 2.5e-35 121.7 0.0 4.1e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KNZ79379.1 - 1.9e-08 34.8 0.0 9.1e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_lid_3 PF17862.1 KNZ79379.1 - 1.9e-05 24.4 0.1 5.1e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KNZ79379.1 - 0.0002 21.6 0.0 0.0044 17.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KNZ79379.1 - 0.00022 21.2 0.0 0.00064 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNZ79379.1 - 0.00038 20.6 0.0 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KNZ79379.1 - 0.00065 20.1 0.1 0.0067 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 KNZ79379.1 - 0.00095 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) HATPase_c_3 PF13589.6 KNZ79379.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RuvB_N PF05496.12 KNZ79379.1 - 0.01 15.6 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 KNZ79379.1 - 0.013 15.7 0.0 0.054 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KNZ79379.1 - 0.025 15.1 0.0 0.18 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KNZ79379.1 - 0.036 13.8 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KNZ79379.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 KNZ79379.1 - 0.051 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 KNZ79379.1 - 0.071 12.5 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KNZ79379.1 - 0.073 13.5 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KNZ79379.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 KNZ79379.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 KNZ79379.1 - 0.18 11.7 0.4 13 5.7 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 KNZ79380.1 - 5e-46 157.2 0.0 9.3e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79380.1 - 2.6e-18 66.2 0.0 5.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ79380.1 - 0.031 14.2 0.1 0.066 13.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.16 KNZ79380.1 - 0.056 13.6 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Ank_2 PF12796.7 KNZ79381.1 - 8e-17 61.6 0.0 9.2e-11 42.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ79381.1 - 1.8e-14 53.9 0.0 4.3e-11 43.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ79381.1 - 9e-10 38.0 0.0 0.029 14.9 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat DnaJ PF00226.31 KNZ79381.1 - 1.7e-09 37.7 0.0 5.5e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain Ank PF00023.30 KNZ79381.1 - 1.9e-07 31.2 0.1 0.066 13.7 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 KNZ79381.1 - 1.7e-05 25.0 0.0 0.0031 17.8 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Zn_clus PF00172.18 KNZ79382.1 - 0.0012 18.9 17.0 0.0017 18.4 17.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KNZ79383.1 - 1.9e-28 99.6 0.5 9.4e-28 97.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79383.1 - 2.5e-28 99.1 0.0 4.6e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PriA_C PF18074.1 KNZ79383.1 - 0.043 14.6 0.5 0.11 13.3 0.5 1.6 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain ING PF12998.7 KNZ79384.1 - 2.1e-05 25.0 4.2 0.031 14.8 0.1 3.1 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding DHR10 PF18595.1 KNZ79385.1 - 5.9e-34 116.6 23.2 5.9e-34 116.6 23.2 4.2 2 1 2 4 4 4 1 Designed helical repeat protein 10 domain Nuf2 PF03800.14 KNZ79385.1 - 2.5e-33 115.1 0.0 8.2e-33 113.5 0.0 1.9 1 0 0 1 1 1 1 Nuf2 family YabA PF06156.13 KNZ79385.1 - 0.032 14.9 1.3 0.032 14.9 1.3 4.4 1 1 2 4 4 4 0 Initiation control protein YabA GAS PF13851.6 KNZ79385.1 - 0.032 13.6 44.4 0.38 10.1 19.0 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.11 KNZ79385.1 - 0.069 13.0 0.4 0.069 13.0 0.4 3.7 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 KNZ79385.1 - 0.17 12.4 46.9 0.48 11.0 7.3 3.6 1 1 2 3 3 3 0 Apg6 coiled-coil region TSC22 PF01166.18 KNZ79385.1 - 0.22 11.9 0.2 0.22 11.9 0.2 4.8 3 3 3 6 6 6 0 TSC-22/dip/bun family Seryl_tRNA_N PF02403.22 KNZ79385.1 - 0.23 11.7 44.0 0.49 10.7 10.3 4.5 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain MAD PF05557.13 KNZ79385.1 - 0.47 8.8 44.0 0.0055 15.1 19.3 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein HrpB7 PF09486.10 KNZ79385.1 - 0.71 10.3 34.2 0.51 10.7 3.1 4.3 2 2 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) Mod_r PF07200.13 KNZ79385.1 - 1.2 9.2 35.7 0.32 11.1 0.3 3.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 KNZ79385.1 - 2 7.3 45.2 4.1 6.2 9.6 2.8 1 1 1 2 2 2 0 Spc7 kinetochore protein HAP1_N PF04849.13 KNZ79385.1 - 4.7 6.3 39.5 0.031 13.5 3.5 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 KNZ79385.1 - 5.7 7.3 39.8 9.5 6.6 23.5 2.3 1 1 1 2 2 2 0 Fez1 NPV_P10 PF05531.12 KNZ79385.1 - 6 7.4 12.9 0.72 10.4 1.8 3.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 KNZ79385.1 - 9.3 6.3 40.5 1.9 8.5 8.9 3.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Helicase_C PF00271.31 KNZ79386.1 - 4.1e-15 56.1 0.0 1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KNZ79386.1 - 5.2e-13 49.5 2.0 1.6e-12 47.9 2.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 KNZ79386.1 - 2.5e-10 40.2 0.0 6.9e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 RQC domain Radical_SAM PF04055.21 KNZ79386.1 - 0.0059 17.0 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 2 Radical SAM superfamily DEAD PF00270.29 KNZ79387.1 - 1.6e-44 151.8 0.0 5.9e-44 149.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ79387.1 - 2.2e-27 95.6 0.0 2.7e-26 92.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ79387.1 - 0.00021 21.3 0.0 0.00063 19.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KNZ79387.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SAM_DrpA PF18255.1 KNZ79387.1 - 0.16 12.3 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 DNA processing protein A sterile alpha motif domain zf-CCHC_4 PF14392.6 KNZ79387.1 - 0.23 11.2 2.1 0.29 10.9 0.9 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 KNZ79387.1 - 0.75 10.0 2.3 1.3 9.2 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle PGM_PMM_I PF02878.16 KNZ79388.1 - 5.4e-27 94.2 0.0 9e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 KNZ79388.1 - 1.1e-17 64.5 0.0 5.6e-17 62.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 KNZ79388.1 - 3.3e-17 62.7 0.1 6.1e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PHD PF00628.29 KNZ79388.1 - 1.2e-05 25.1 1.5 3.1e-05 23.8 1.5 1.6 1 0 0 1 1 1 1 PHD-finger PGM_PMM_IV PF00408.20 KNZ79388.1 - 0.00035 20.7 0.0 0.0013 18.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MCM_bind PF09739.9 KNZ79389.1 - 1.3e-69 235.2 0.1 1.4e-65 221.9 0.0 3.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor Mrr_cat_2 PF13156.6 KNZ79389.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease ATP-synt_F PF01990.17 KNZ79389.1 - 0.18 12.2 0.1 0.42 11.0 0.1 1.6 1 0 0 1 1 1 0 ATP synthase (F/14-kDa) subunit CDC50 PF03381.15 KNZ79390.1 - 1.8e-90 303.2 0.0 2.3e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Fve PF09259.11 KNZ79390.1 - 0.031 14.4 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Fungal immunomodulatory protein Fve RTC PF01137.21 KNZ79391.1 - 6.3e-81 270.8 0.0 7.2e-81 270.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 KNZ79391.1 - 4.1e-24 85.1 0.3 7.4e-24 84.2 0.3 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HOOK PF05622.12 KNZ79392.1 - 1.1e-56 192.5 39.3 1.1e-56 192.5 39.3 3.1 1 1 2 3 3 3 1 HOOK protein bZIP_1 PF00170.21 KNZ79392.1 - 0.0026 17.8 1.2 0.0026 17.8 1.2 8.9 7 2 1 9 9 9 3 bZIP transcription factor NYD-SP28_assoc PF14775.6 KNZ79392.1 - 0.025 14.6 1.2 0.025 14.6 1.2 6.2 6 1 0 6 6 6 0 Sperm tail C-terminal domain DUF728 PF05304.12 KNZ79392.1 - 1.2 9.0 4.6 3.4 7.5 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF728) Pox_A_type_inc PF04508.12 KNZ79392.1 - 1.5 8.8 11.9 18 5.4 0.1 5.8 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Lzipper-MIP1 PF14389.6 KNZ79392.1 - 2.3 8.6 24.8 0.081 13.2 3.0 4.7 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF3972 PF13118.6 KNZ79393.1 - 0.092 13.2 11.7 1.2 9.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Fez1 PF06818.15 KNZ79393.1 - 0.47 10.9 22.0 0.1 13.0 17.8 1.8 1 1 1 2 2 2 0 Fez1 Pox_A_type_inc PF04508.12 KNZ79393.1 - 0.58 10.1 11.7 1 9.3 0.7 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 KNZ79393.1 - 1.3 9.0 8.5 0.37 10.7 1.4 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C4H2 PF10146.9 KNZ79393.1 - 1.8 8.8 14.5 0.8 10.0 12.0 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein TMPIT PF07851.13 KNZ79393.1 - 6 6.0 12.9 2.7 7.2 2.7 2.2 2 0 0 2 2 2 0 TMPIT-like protein DUF2304 PF10066.9 KNZ79393.1 - 6.5 7.0 4.7 23 5.3 1.5 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) V_ATPase_I PF01496.19 KNZ79393.1 - 7.4 4.4 13.1 7.8 4.3 12.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 KNZ79393.1 - 8.3 4.8 9.1 10 4.5 9.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family ESCRT-II PF05871.12 KNZ79394.1 - 7.5e-33 113.7 0.1 8.6e-33 113.5 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Glyco_hydro_35 PF01301.19 KNZ79395.1 - 2.8e-69 234.2 1.5 4.6e-69 233.4 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KNZ79395.1 - 3.3e-43 146.9 2.2 5.2e-28 97.9 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KNZ79395.1 - 9.6e-38 129.8 2.4 1.1e-30 106.8 2.2 2.4 1 1 1 2 2 2 2 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KNZ79395.1 - 1.6e-14 53.2 0.0 5.4e-14 51.5 0.0 1.9 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 KNZ79395.1 - 0.0065 15.9 0.3 0.026 13.9 0.1 2.0 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF1412 PF07203.11 KNZ79395.1 - 0.05 13.8 0.6 0.36 11.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) PvlArgDC PF01862.16 KNZ79397.1 - 0.019 14.8 0.1 0.066 13.0 0.1 1.9 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) TMF_DNA_bd PF12329.8 KNZ79397.1 - 0.44 10.6 5.8 0.83 9.7 5.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Methyltransf_2 PF00891.18 KNZ79398.1 - 6.4e-12 45.2 0.1 2.4e-11 43.3 0.1 1.8 1 1 0 1 1 1 1 O-methyltransferase domain CRAL_TRIO_2 PF13716.6 KNZ79398.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain Ribosomal_L7Ae PF01248.26 KNZ79399.1 - 5.6e-25 86.9 0.1 7.2e-25 86.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KNZ79399.1 - 0.00015 21.9 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KNZ79399.1 - 0.0015 18.3 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain peroxidase PF00141.23 KNZ79400.1 - 1.2e-25 90.5 0.1 2.7e-25 89.4 0.1 1.5 1 0 0 1 1 1 1 Peroxidase DHHC PF01529.20 KNZ79401.1 - 2.3e-34 118.4 5.3 2.3e-34 118.4 5.3 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Fungal_trans PF04082.18 KNZ79402.1 - 3.4e-25 88.6 0.0 5.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Syja_N PF02383.18 KNZ79403.1 - 5.7e-91 305.2 0.0 8.1e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KNZ79403.1 - 9.7e-27 93.0 0.0 1.8e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase CID_GANP PF16766.5 KNZ79403.1 - 0.36 11.1 2.5 0.22 11.7 0.3 1.8 2 0 0 2 2 2 0 Binding region of GANP to ENY2 UQ_con PF00179.26 KNZ79404.1 - 2.2e-49 166.7 0.0 2.4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KNZ79404.1 - 0.02 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 KNZ79404.1 - 0.074 13.4 0.6 0.16 12.3 0.6 1.8 1 1 0 1 1 1 0 RWD domain DUF1713 PF08213.11 KNZ79406.1 - 0.00027 20.8 12.1 0.00054 19.8 12.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) CLP1_P PF16575.5 KNZ79407.1 - 4.4e-37 127.7 0.0 7.9e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 KNZ79407.1 - 4e-34 116.7 0.0 8.1e-34 115.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 KNZ79407.1 - 2.6e-27 95.5 0.0 4.8e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 KNZ79407.1 - 0.0034 17.2 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 KNZ79407.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 KNZ79407.1 - 0.21 10.9 0.0 2.9 7.2 0.0 2.6 2 1 1 3 3 3 0 Bacterial TniB protein MFS_1 PF07690.16 KNZ79408.1 - 4.1e-32 111.5 44.4 9.4e-29 100.4 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KNZ79408.1 - 0.00089 18.7 4.0 0.00089 18.7 4.0 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Herpes_U26 PF07402.11 KNZ79408.1 - 0.013 15.1 3.9 0.018 14.6 0.2 2.5 3 0 0 3 3 3 0 Human herpesvirus U26 protein TMEM135_C_rich PF15982.5 KNZ79408.1 - 0.033 14.8 1.1 0.076 13.6 1.1 1.7 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 DUF4131 PF13567.6 KNZ79408.1 - 0.15 11.7 9.0 2.8 7.5 1.6 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) AAA PF00004.29 KNZ79409.1 - 1.4e-14 54.7 0.0 4.4e-14 53.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KNZ79409.1 - 3.2e-06 27.2 0.0 8.3e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 KNZ79409.1 - 1e-05 25.4 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KNZ79409.1 - 2.2e-05 24.9 0.0 0.0023 18.3 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 KNZ79409.1 - 0.00066 19.3 0.0 0.075 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KNZ79409.1 - 0.00085 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNZ79409.1 - 0.00087 19.6 0.0 0.036 14.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KNZ79409.1 - 0.0011 19.0 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 KNZ79409.1 - 0.0033 17.7 0.0 0.0096 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_33 PF13671.6 KNZ79409.1 - 0.0059 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KNZ79409.1 - 0.014 15.3 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 KNZ79409.1 - 0.021 14.7 0.0 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 KNZ79409.1 - 0.024 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KNZ79409.1 - 0.029 14.9 0.0 0.088 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KNZ79409.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 KNZ79409.1 - 0.079 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta PF06144.13 KNZ79409.1 - 0.083 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit NTPase_1 PF03266.15 KNZ79409.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NTPase TIP49 PF06068.13 KNZ79409.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 KNZ79409.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KNZ79409.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF3835 PF12927.7 KNZ79410.1 - 9.2e-05 23.2 6.1 9.2e-05 23.2 6.1 5.3 4 2 0 4 4 4 1 Domain of unknown function (DUF3835) Salt_tol_Pase PF09506.10 KNZ79410.1 - 0.034 12.9 1.0 0.056 12.2 1.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Pkinase_Tyr PF07714.17 KNZ79411.1 - 1.4e-44 152.3 0.0 2e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ79411.1 - 2.1e-44 151.9 0.0 3.4e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ79411.1 - 0.0045 16.9 0.6 0.077 12.9 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family SAP PF02037.27 KNZ79411.1 - 0.13 12.1 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 SAP domain Kinase-like PF14531.6 KNZ79411.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SurA_N_2 PF13623.6 KNZ79411.1 - 0.22 11.4 0.6 0.92 9.4 0.3 2.0 2 0 0 2 2 2 0 SurA N-terminal domain UbiA PF01040.18 KNZ79413.1 - 2.3e-49 168.0 21.8 2.8e-49 167.7 21.8 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Retrotran_gag_2 PF14223.6 KNZ79414.1 - 8.6e-05 22.2 0.2 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type CFC PF09443.10 KNZ79414.1 - 0.37 10.7 1.9 0.39 10.6 0.3 1.8 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) RNase_H PF00075.24 KNZ79417.1 - 0.00018 21.7 0.0 0.0039 17.4 0.0 2.4 2 1 1 3 3 3 1 RNase H zf-CCHC PF00098.23 KNZ79419.1 - 0.11 12.6 10.8 2.8 8.2 5.5 2.9 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.27 KNZ79420.1 - 0.0038 16.8 0.1 0.0044 16.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DNA_III_psi PF03603.13 KNZ79420.1 - 0.13 12.5 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III psi subunit Helitron_like_N PF14214.6 KNZ79422.1 - 3.5e-15 56.7 0.0 5.1e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF1796 PF08795.10 KNZ79423.1 - 0.0036 17.3 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) NAD_binding_4 PF07993.12 KNZ79425.1 - 6.1e-34 117.4 0.0 8.7e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ79425.1 - 3.6e-14 52.2 0.0 3.9e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 KNZ79425.1 - 8.4e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KNZ79425.1 - 0.0017 18.6 0.0 0.0054 17.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 KNZ79425.1 - 0.029 14.3 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 KR domain DUF2802 PF10975.8 KNZ79426.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) CFEM PF05730.11 KNZ79427.1 - 2.7e-11 43.4 13.9 5.4e-11 42.4 13.9 1.5 1 0 0 1 1 1 1 CFEM domain TMV_coat PF00721.21 KNZ79429.1 - 0.07 13.0 0.6 0.13 12.1 0.6 1.4 1 1 0 1 1 1 0 Virus coat protein (TMV like) DUF4801 PF16059.5 KNZ79429.1 - 0.29 11.1 2.9 0.58 10.2 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4801) LysM PF01476.20 KNZ79430.1 - 3.4e-26 91.0 0.8 2.5e-06 27.4 0.0 6.5 6 0 0 6 6 6 6 LysM domain PRIMA1 PF16101.5 KNZ79431.1 - 0.095 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 WEMBL PF05701.11 KNZ79435.1 - 0.0043 15.8 6.9 0.006 15.4 6.9 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Borrelia_P83 PF05262.11 KNZ79435.1 - 0.01 14.3 6.2 0.012 14.2 6.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3584 PF12128.8 KNZ79435.1 - 0.022 12.3 6.7 0.026 12.1 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) YscO PF07321.12 KNZ79435.1 - 0.034 14.1 14.5 0.041 13.8 14.0 1.5 1 1 0 1 1 1 0 Type III secretion protein YscO APG6_N PF17675.1 KNZ79435.1 - 0.035 14.6 4.9 0.035 14.6 4.9 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region EzrA PF06160.12 KNZ79435.1 - 0.058 11.6 2.9 0.083 11.1 2.9 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 KNZ79435.1 - 0.079 12.5 2.4 0.098 12.2 2.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_CLD_2 PF14197.6 KNZ79435.1 - 0.12 12.5 11.1 0.057 13.5 3.4 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 SNARE PF05739.19 KNZ79435.1 - 0.12 12.4 5.8 0.58 10.2 0.7 2.4 1 1 1 2 2 2 0 SNARE domain DUF4407 PF14362.6 KNZ79435.1 - 0.14 11.5 5.3 0.17 11.2 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 KNZ79435.1 - 0.15 11.1 3.9 0.18 10.9 3.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 KNZ79435.1 - 0.16 11.4 6.9 0.21 11.1 6.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TMPIT PF07851.13 KNZ79435.1 - 0.22 10.7 1.8 0.26 10.5 1.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mod_r PF07200.13 KNZ79435.1 - 0.24 11.5 6.0 0.32 11.1 6.0 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4200 PF13863.6 KNZ79435.1 - 0.24 11.8 9.8 0.33 11.3 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_23 PF13476.6 KNZ79435.1 - 0.31 11.5 2.1 0.38 11.2 2.1 1.1 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.12 KNZ79435.1 - 0.35 11.3 6.4 0.38 11.2 5.4 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) OmpH PF03938.14 KNZ79435.1 - 0.42 11.0 10.2 0.55 10.6 10.2 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 KNZ79435.1 - 0.89 8.4 8.0 1.1 8.0 8.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PHM7_cyt PF14703.6 KNZ79435.1 - 1.2 9.3 4.3 0.41 10.9 1.4 1.7 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CHD5 PF04420.14 KNZ79435.1 - 5.4 6.9 7.8 5.9 6.7 4.1 2.1 1 1 1 2 2 2 0 CHD5-like protein E2F_CC-MB PF16421.5 KNZ79435.1 - 5.6 7.4 7.1 7.4 7.0 3.5 2.2 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain Lip_prot_lig_C PF10437.9 KNZ79436.1 - 0.0031 17.5 0.5 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus 4HB_MCP_1 PF12729.7 KNZ79436.1 - 0.011 15.3 0.0 0.035 13.7 0.0 1.7 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Prefoldin_3 PF13758.6 KNZ79436.1 - 0.1 12.6 1.3 2 8.5 0.3 2.3 2 1 0 2 2 2 0 Prefoldin subunit WD40 PF00400.32 KNZ79438.1 - 6.6e-12 45.8 5.4 2.8e-08 34.3 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79438.1 - 9e-08 32.3 0.0 0.00023 21.4 0.1 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ79438.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A F-box-like PF12937.7 KNZ79439.1 - 3.2e-10 39.7 1.0 1.1e-09 38.1 1.0 2.0 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.6 KNZ79440.1 - 1.4e-36 126.2 0.5 1.1e-34 120.0 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ79440.1 - 2.7e-35 121.6 1.6 2.7e-35 121.6 1.6 2.0 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KNZ79440.1 - 3.8e-06 26.9 0.1 7.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 KR domain MelC1 PF06236.11 KNZ79440.1 - 0.11 12.6 0.6 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 F-box PF00646.33 KNZ79441.1 - 0.028 14.3 0.5 0.084 12.8 0.5 1.8 1 0 0 1 1 1 0 F-box domain ATPase_2 PF01637.18 KNZ79441.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Endonuc-PvuII PF09225.10 KNZ79441.1 - 0.11 12.3 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease PvuII Citrate_bind PF16114.5 KNZ79442.1 - 7.3e-90 299.2 0.0 1.5e-89 298.2 0.0 1.6 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 KNZ79442.1 - 3.7e-19 69.0 0.0 7.3e-17 61.5 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 KNZ79442.1 - 1.4e-14 54.2 0.0 3.3e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 KNZ79442.1 - 1.1e-13 51.6 0.0 2.8e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 KNZ79442.1 - 4.9e-09 36.1 0.0 8.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 KNZ79442.1 - 2.8e-05 23.9 0.0 6.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Glyco_hydro_88 PF07470.13 KNZ79443.1 - 1.3e-13 50.8 0.1 2.6e-13 49.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 FmdA_AmdA PF03069.15 KNZ79444.1 - 4.2e-89 299.0 0.0 1.1e-55 189.0 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family zf-C5HC2 PF02928.16 KNZ79445.1 - 0.027 14.9 0.7 1.9 8.9 0.1 2.1 2 0 0 2 2 2 0 C5HC2 zinc finger AdoMet_MTase PF07757.13 KNZ79446.1 - 1.2e-32 112.6 0.2 2.7e-31 108.2 0.2 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 KNZ79446.1 - 0.014 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Goodbye PF17109.5 KNZ79448.1 - 0.012 16.0 0.3 0.04 14.4 0.1 1.8 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain NACHT_N PF17100.5 KNZ79448.1 - 0.068 13.0 0.8 0.95 9.3 0.3 2.5 1 1 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase DUF1275 PF06912.11 KNZ79449.1 - 1.3e-30 106.8 11.4 1.6e-30 106.4 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2231 PF09990.9 KNZ79449.1 - 0.011 16.2 0.6 0.044 14.2 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) DUF309 PF03745.14 KNZ79449.1 - 0.2 11.4 0.1 0.71 9.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF309) Rad60-SLD_2 PF13881.6 KNZ79450.1 - 2.5e-16 59.7 0.0 4.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KNZ79450.1 - 0.00021 21.0 0.0 0.0015 18.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KNZ79450.1 - 0.11 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RTA1 PF04479.13 KNZ79451.1 - 2e-60 203.9 8.2 2.9e-60 203.4 8.2 1.2 1 0 0 1 1 1 1 RTA1 like protein Ribosomal_L38e PF01781.18 KNZ79453.1 - 1.4e-24 86.0 0.2 1.5e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family E1-E2_ATPase PF00122.20 KNZ79454.1 - 1.1e-21 77.2 1.7 2.1e-21 76.2 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KNZ79454.1 - 9.7e-17 62.0 0.1 9.1e-10 39.2 0.2 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ79454.1 - 5.2e-05 23.2 0.0 0.00012 22.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KNZ79454.1 - 0.094 12.4 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 KNZ79455.1 - 2.6e-23 82.7 0.0 1.8e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ79455.1 - 2.3e-11 44.1 0.1 5.9e-10 39.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ79455.1 - 0.0019 17.5 0.0 0.39 9.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.8 KNZ79455.1 - 0.043 13.6 0.7 4 7.3 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3533 PF12051.8 KNZ79456.1 - 3.9e-92 309.1 13.3 4.4e-92 308.9 13.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.7 KNZ79456.1 - 1.2e-05 24.6 16.5 1.8e-05 24.0 16.5 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein Pga1 PF10333.9 KNZ79456.1 - 0.01 15.7 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator F-box-like PF12937.7 KNZ79457.1 - 0.00024 20.9 0.4 0.0006 19.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ79457.1 - 0.0045 16.8 0.1 0.017 15.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain DUF1746 PF08508.10 KNZ79457.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1746) DIOX_N PF14226.6 KNZ79458.1 - 3.4e-20 73.0 0.0 7.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ79458.1 - 2.4e-13 50.4 0.0 7.6e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 KNZ79459.1 - 5.6e-17 61.7 0.0 1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ79459.1 - 0.0003 20.8 14.9 0.00054 20.0 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GPI-anchored PF10342.9 KNZ79460.1 - 2.2e-05 25.1 0.0 2.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 KNZ79460.1 - 0.067 13.0 0.3 0.097 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4148 PF13663.6 KNZ79460.1 - 0.15 12.3 0.5 0.28 11.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) GLTP PF08718.11 KNZ79461.1 - 7.3e-39 133.4 0.1 8.7e-39 133.2 0.1 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Fib_alpha PF08702.10 KNZ79463.1 - 0.00053 20.2 4.4 0.00053 20.2 4.4 1.9 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family BST2 PF16716.5 KNZ79463.1 - 0.008 16.7 4.2 0.008 16.7 4.2 2.5 2 1 0 2 2 2 1 Bone marrow stromal antigen 2 DUF1644 PF07800.12 KNZ79463.1 - 0.011 15.8 0.9 4.2 7.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) FapA PF03961.13 KNZ79463.1 - 0.02 13.6 2.5 0.033 12.8 2.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 KNZ79463.1 - 0.17 12.4 0.1 22 5.6 0.1 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 KNZ79463.1 - 0.2 12.4 9.5 0.071 13.8 3.4 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 KNZ79463.1 - 0.26 9.2 0.8 0.42 8.5 0.8 1.2 1 0 0 1 1 1 0 Prominin ATP-synt_B PF00430.18 KNZ79463.1 - 0.28 11.3 11.7 0.3 11.2 0.6 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) FYDLN_acid PF09538.10 KNZ79463.1 - 0.34 11.6 5.4 0.29 11.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) COG2 PF06148.11 KNZ79463.1 - 0.34 11.0 9.6 0.049 13.7 5.0 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 EMC3_TMCO1 PF01956.16 KNZ79463.1 - 0.72 9.6 3.9 2.6 7.7 0.8 2.6 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DUF948 PF06103.11 KNZ79463.1 - 0.86 9.9 3.7 0.83 10.0 0.9 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) WASH-7_C PF14746.6 KNZ79463.1 - 1 9.1 6.6 0.25 11.0 1.0 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Spc7 PF08317.11 KNZ79463.1 - 1.4 7.8 15.5 0.21 10.4 8.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 KNZ79463.1 - 1.7 8.9 19.7 25 5.1 13.8 3.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 KNZ79463.1 - 2.7 8.1 8.0 2.2 8.3 2.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FH2 PF02181.23 KNZ79463.1 - 3.1 6.8 12.3 0.064 12.4 4.1 2.0 2 1 1 3 3 3 0 Formin Homology 2 Domain Cytochrom_B562 PF07361.11 KNZ79463.1 - 4.3 8.1 10.2 16 6.2 0.1 3.1 2 1 1 3 3 3 0 Cytochrome b562 TMPIT PF07851.13 KNZ79463.1 - 9 5.4 7.2 1.8 7.8 2.2 2.0 2 0 0 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 KNZ79463.1 - 9.3 6.7 18.5 0.66 10.4 5.6 2.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF2207 PF09972.9 KNZ79464.1 - 0.017 13.9 3.7 1.2 7.8 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) RNase_H PF00075.24 KNZ79466.1 - 0.029 14.5 1.1 0.058 13.6 0.3 2.0 2 1 0 2 2 2 0 RNase H Sec10 PF07393.11 KNZ79468.1 - 3.4e-113 379.5 0.0 1.5e-112 377.4 0.0 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 zf_C2H2_13 PF18508.1 KNZ79469.1 - 0.096 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc finger domain DUF2264 PF10022.9 KNZ79469.1 - 0.14 11.2 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Pkinase PF00069.25 KNZ79470.1 - 0.0028 17.1 0.3 0.098 12.0 0.1 2.5 2 1 1 3 3 3 2 Protein kinase domain UPF0669 PF17065.5 KNZ79470.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 Pkinase_fungal PF17667.1 KNZ79470.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GLTP PF08718.11 KNZ79474.1 - 2.1e-31 109.2 0.0 2.4e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Col_cuticle_N PF01484.17 KNZ79474.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain p450 PF00067.22 KNZ79475.1 - 1.7e-15 56.7 0.0 1.9e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.20 KNZ79477.1 - 3.9e-135 450.3 0.0 5e-135 449.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KNZ79477.1 - 4.1e-09 36.2 0.1 2.3e-08 33.7 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KNZ79477.1 - 5.3e-07 29.1 0.0 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KNZ79477.1 - 1.2e-06 27.7 0.1 2.1e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KNZ79477.1 - 1.8e-06 27.4 0.0 4.6e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KNZ79477.1 - 0.017 13.7 0.0 0.03 12.9 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.20 KNZ79478.1 - 1.6e-34 119.1 0.0 1.7e-33 115.7 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_3_C PF01915.22 KNZ79480.1 - 4.3e-45 154.2 0.0 6.1e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ79480.1 - 2.7e-39 135.4 0.0 4e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ79480.1 - 2.9e-07 30.5 0.0 5.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 KNZ79481.1 - 1.2e-39 136.4 0.0 1.7e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ79481.1 - 1.9e-36 126.1 0.0 2.7e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ79481.1 - 6.6e-19 67.8 0.0 1.3e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Zip PF02535.22 KNZ79482.1 - 3.1e-62 210.7 6.4 3.6e-62 210.5 6.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 KNZ79484.1 - 9.3e-58 196.0 7.7 1.4e-57 195.4 7.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Aldedh PF00171.22 KNZ79485.1 - 4.7e-16 58.4 0.1 5.8e-16 58.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RT_RNaseH PF17917.1 KNZ79487.1 - 0.065 13.5 0.0 0.088 13.1 0.0 1.2 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 KNZ79489.1 - 6.6e-12 45.3 1.0 1e-11 44.7 1.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain NAD_binding_10 PF13460.6 KNZ79490.1 - 3.5e-10 40.1 0.0 0.00034 20.5 0.0 2.2 1 1 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 KNZ79490.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ApbA PF02558.16 KNZ79490.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 KNZ79491.1 - 3.8e-49 167.7 0.0 3.4e-48 164.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KNZ79492.1 - 4.3e-47 160.9 0.0 7.2e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.24 KNZ79493.1 - 2.6e-24 85.9 15.2 2.1e-23 83.0 15.2 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ79493.1 - 3e-14 52.7 12.9 1.1e-10 41.0 3.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_integrase PF00589.22 KNZ79495.1 - 0.024 14.4 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Phage integrase family HNH_2 PF13391.6 KNZ79496.1 - 0.0019 18.3 0.0 0.0064 16.6 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease RVT_1 PF00078.27 KNZ79497.1 - 0.0013 18.3 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Terpene_synth_C PF03936.16 KNZ79499.1 - 6.9e-07 28.9 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain APG12 PF04110.13 KNZ79500.1 - 1.1e-30 105.9 0.0 1.4e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KNZ79500.1 - 0.0017 18.5 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Terpene_synth_C PF03936.16 KNZ79502.1 - 5e-07 29.4 0.1 7.3e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Sec23_helical PF04815.15 KNZ79504.1 - 0.054 13.3 0.1 0.054 13.3 0.1 1.1 1 0 0 1 1 1 0 Sec23/Sec24 helical domain AidB_N PF18158.1 KNZ79505.1 - 1.4e-26 93.3 0.0 2.4e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KNZ79505.1 - 6.6e-19 68.6 0.9 1.2e-18 67.8 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KNZ79505.1 - 9.4e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KNZ79505.1 - 0.0016 18.7 0.3 0.0039 17.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain 4HBT PF03061.22 KNZ79506.1 - 2.2e-10 40.8 0.2 3e-10 40.3 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Alg6_Alg8 PF03155.15 KNZ79507.1 - 3.2e-137 458.4 26.6 4.2e-137 458.0 26.6 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Thaumatin PF00314.17 KNZ79508.1 - 7.3e-66 221.9 14.8 8.9e-66 221.6 14.8 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KNZ79508.1 - 0.0071 15.7 1.3 0.03 13.6 0.4 2.4 1 1 1 2 2 2 1 Beta-1,3-glucanase APH PF01636.23 KNZ79513.1 - 1.4e-05 25.1 0.1 2.1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ79513.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 KNZ79513.1 - 0.037 13.6 0.0 0.075 12.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Thaumatin PF00314.17 KNZ79514.1 - 2.8e-65 219.9 14.4 3.1e-65 219.8 14.4 1.0 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KNZ79514.1 - 0.0028 17.0 2.0 0.0085 15.4 0.2 2.4 1 1 1 2 2 2 1 Beta-1,3-glucanase Asparaginase_II PF06089.12 KNZ79514.1 - 0.2 10.7 2.3 0.27 10.2 2.3 1.1 1 0 0 1 1 1 0 L-asparaginase II Lactonase PF10282.9 KNZ79516.1 - 3.4e-37 128.5 0.0 4.3e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 KNZ79516.1 - 0.016 15.6 0.7 2.8 8.5 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain Catalase PF00199.19 KNZ79517.1 - 6.3e-190 631.2 0.0 7.9e-190 630.9 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KNZ79517.1 - 1.8e-15 56.9 0.1 5e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive EABR PF12180.8 KNZ79517.1 - 0.011 15.3 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 HMG_box PF00505.19 KNZ79518.1 - 0.0061 16.9 1.4 2.3 8.7 0.0 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box rRNA_proc-arch PF13234.6 KNZ79519.1 - 6.8e-88 295.1 0.0 1.3e-87 294.2 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KNZ79519.1 - 2.9e-54 183.2 0.9 6e-54 182.1 0.9 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 KNZ79519.1 - 1.1e-17 64.4 0.0 1.1e-16 61.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ79519.1 - 7.7e-08 32.7 0.0 1.3e-06 28.8 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ79519.1 - 0.00039 20.5 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 KNZ79519.1 - 0.0056 15.8 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KNZ79519.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Dehydratase_SU PF02287.15 KNZ79519.1 - 0.12 12.4 0.1 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 Dehydratase small subunit ATG16 PF08614.11 KNZ79519.1 - 0.92 9.7 5.3 1.6 8.9 0.4 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_hydro_18 PF00704.28 KNZ79520.1 - 1e-77 262.0 7.3 1.3e-77 261.6 7.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12_2 PF14600.6 KNZ79520.1 - 1.7 8.7 11.8 0.44 10.5 4.2 3.0 3 0 0 3 3 3 0 Cellulose-binding domain Ras PF00071.22 KNZ79521.1 - 2.7e-31 108.4 0.5 1.2e-30 106.3 0.5 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KNZ79521.1 - 6.4e-23 81.2 0.4 1.8e-22 79.8 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ79521.1 - 4.6e-07 29.4 0.1 8e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ79521.1 - 1.7e-05 24.3 0.3 2.4e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KNZ79521.1 - 0.0049 16.1 2.1 0.15 11.2 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit DLIC PF05783.11 KNZ79521.1 - 0.017 14.0 0.4 1.8 7.3 0.0 2.3 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 KNZ79521.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 KNZ79521.1 - 0.12 11.8 0.0 2.5 7.5 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein CybS PF05328.12 KNZ79522.1 - 1e-44 151.4 0.1 1.3e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Pkinase PF00069.25 KNZ79523.1 - 1.8e-71 240.6 0.0 2.3e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79523.1 - 2e-34 119.1 0.0 2.7e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KNZ79523.1 - 4.3e-13 49.7 2.5 8.8e-13 48.7 2.5 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KNZ79523.1 - 2.1e-05 23.6 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KNZ79523.1 - 0.0024 17.2 0.0 0.0049 16.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 KNZ79523.1 - 0.0084 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 KNZ79523.1 - 0.035 13.7 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KNZ79523.1 - 0.097 12.6 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79523.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family polyprenyl_synt PF00348.17 KNZ79524.1 - 6.4e-81 271.2 0.0 8.9e-81 270.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase GMC_oxred_C PF05199.13 KNZ79525.1 - 1.1e-16 61.7 0.1 2.5e-16 60.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KNZ79525.1 - 1.8e-16 60.4 0.0 9.4e-16 58.0 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KNZ79525.1 - 3.5e-07 29.7 0.0 4.8e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KNZ79525.1 - 1.3e-05 25.3 0.2 4.8e-05 23.5 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ79525.1 - 4.2e-05 23.3 0.0 0.00023 20.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KNZ79525.1 - 9.9e-05 21.7 0.2 0.00017 21.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KNZ79525.1 - 0.00023 20.0 0.0 0.00036 19.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KNZ79525.1 - 0.00036 19.9 0.1 0.0006 19.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ79525.1 - 0.0044 16.3 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KNZ79525.1 - 0.013 14.9 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KNZ79525.1 - 0.016 14.5 0.3 0.037 13.3 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ79525.1 - 0.02 13.9 0.1 0.031 13.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Mannosyl_trans2 PF04188.13 KNZ79526.1 - 3e-36 125.7 22.8 2.8e-33 115.9 20.7 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) Spc7 PF08317.11 KNZ79527.1 - 0.067 12.1 7.3 0.08 11.8 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phlebovirus_NSM PF07246.11 KNZ79527.1 - 0.76 9.1 7.0 0.94 8.8 7.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DDE_Tnp_1_6 PF13751.6 KNZ79527.1 - 0.94 9.7 5.0 1.6 9.0 5.0 1.4 1 1 0 1 1 1 0 Transposase DDE domain PEARLI-4 PF05278.12 KNZ79527.1 - 2 7.9 10.4 1.8 8.1 9.4 1.4 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) RNase_H PF00075.24 KNZ79528.1 - 3.4e-08 33.8 0.2 7.8e-08 32.6 0.2 1.6 1 0 0 1 1 1 1 RNase H F-box-like PF12937.7 KNZ79529.1 - 5e-07 29.5 2.8 2.5e-06 27.3 0.6 3.0 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.7 KNZ79531.1 - 0.0049 16.7 0.1 0.013 15.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KNZ79531.1 - 0.17 12.3 0.1 0.17 12.3 0.1 3.8 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KNZ79533.1 - 1.9e-09 37.3 0.5 3.3e-08 33.3 0.1 2.9 2 1 0 2 2 2 1 F-box-like Bromodomain PF00439.25 KNZ79536.1 - 3.7e-21 75.0 0.2 7e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 Bromodomain EF-hand_1 PF00036.32 KNZ79536.1 - 8.3e-19 65.7 0.9 2.4e-05 23.6 0.1 4.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 KNZ79536.1 - 2.8e-18 64.2 0.9 4.3e-06 26.2 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 KNZ79536.1 - 1.6e-15 57.3 0.6 3.1e-06 27.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KNZ79536.1 - 8.4e-13 47.2 1.2 0.0095 15.4 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KNZ79536.1 - 7.7e-11 41.7 2.2 5.8e-05 22.9 0.0 4.4 3 1 1 4 4 4 3 EF-hand domain pair Bromo_TP PF07524.13 KNZ79536.1 - 0.00026 20.9 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Glyco_hydro_115 PF15979.5 KNZ79537.1 - 5.1e-122 407.5 0.1 9.2e-120 400.1 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KNZ79537.1 - 3.9e-50 170.0 0.0 6.5e-50 169.3 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Sugar_tr PF00083.24 KNZ79538.1 - 1.2e-96 324.4 8.0 3.2e-96 322.9 8.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ79538.1 - 9.1e-27 93.9 25.6 1.1e-25 90.3 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNZ79538.1 - 0.0009 17.8 0.7 0.0019 16.7 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 KNZ79538.1 - 0.0083 15.1 0.3 0.014 14.3 0.3 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Phage_holin_2_3 PF16080.5 KNZ79538.1 - 4.6 7.1 9.3 0.6 9.9 0.2 3.1 3 0 0 3 3 3 0 Bacteriophage holin family HP1 TMEM135_C_rich PF15982.5 KNZ79544.1 - 0.0028 18.2 0.1 0.0082 16.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 CCB1 PF12046.8 KNZ79544.1 - 0.037 13.4 0.6 0.037 13.4 0.6 2.0 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B WD40 PF00400.32 KNZ79545.1 - 4.4e-06 27.3 11.9 0.27 12.2 1.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79545.1 - 0.0093 16.2 0.8 3.7 7.9 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 KNZ79545.1 - 0.08 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DNA_pol_B PF00136.21 KNZ79546.1 - 1.5e-101 340.4 0.0 2e-101 340.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KNZ79546.1 - 8.5e-25 87.6 0.0 1.7e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KNZ79546.1 - 4.7e-13 49.4 8.9 1e-12 48.3 8.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 KNZ79546.1 - 0.036 12.9 0.1 0.062 12.2 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Aldose_epim PF01263.20 KNZ79548.1 - 1.9e-28 99.7 0.0 2.1e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase HEAT PF02985.22 KNZ79549.1 - 5.3e-37 122.7 12.2 0.0041 17.3 0.1 12.7 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 KNZ79549.1 - 1.4e-30 105.5 12.9 5.1e-11 42.8 0.0 7.5 2 2 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 KNZ79549.1 - 2.1e-10 40.9 12.6 0.093 13.3 0.0 8.6 7 2 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KNZ79549.1 - 1.6e-08 35.0 0.1 0.71 10.5 0.0 6.3 3 3 5 8 8 8 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 KNZ79549.1 - 6.9e-05 22.8 3.2 11 6.2 0.0 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 KNZ79549.1 - 7.4e-05 22.9 4.7 0.091 12.8 0.1 5.3 3 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KNZ79549.1 - 0.0032 16.1 6.4 0.34 9.4 0.6 4.2 1 1 3 4 4 4 3 Adaptin N terminal region HEAT_PBS PF03130.16 KNZ79549.1 - 0.027 15.1 3.1 3.7 8.5 0.2 4.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Ecm29 PF13001.7 KNZ79549.1 - 0.28 9.8 3.6 14 4.2 0.1 3.6 3 2 0 3 3 3 0 Proteasome stabiliser Cohesin_HEAT PF12765.7 KNZ79549.1 - 0.62 10.4 3.1 1e+02 3.3 0.4 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_S24e PF01282.19 KNZ79551.1 - 6.4e-35 119.0 0.0 1.2e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Actin PF00022.19 KNZ79552.1 - 4.2e-113 378.0 0.0 2.4e-112 375.5 0.0 1.8 1 1 0 1 1 1 1 Actin ANAPC4 PF12896.7 KNZ79554.1 - 4e-42 144.0 0.7 4e-42 144.0 0.7 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 DEAD PF00270.29 KNZ79554.1 - 4.5e-41 140.5 0.0 2e-40 138.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ79554.1 - 1e-28 99.9 0.0 6.7e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain bZIP_1 PF00170.21 KNZ79554.1 - 0.00032 20.7 3.7 0.00081 19.4 3.7 1.7 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 KNZ79554.1 - 0.061 13.9 0.5 0.25 12.0 0.5 2.1 1 0 0 1 1 1 0 SlyX TolA_bind_tri PF16331.5 KNZ79554.1 - 0.069 13.2 2.1 0.21 11.7 2.1 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation ANAPC4_WD40 PF12894.7 KNZ79554.1 - 0.081 13.2 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain bZIP_Maf PF03131.17 KNZ79554.1 - 0.24 12.0 8.0 0.98 10.0 8.0 2.1 1 0 0 1 1 1 0 bZIP Maf transcription factor YabA PF06156.13 KNZ79554.1 - 0.45 11.2 6.3 0.048 14.3 0.5 2.3 2 0 0 2 2 2 0 Initiation control protein YabA hNIFK_binding PF12196.8 KNZ79559.1 - 0.19 11.3 0.2 0.19 11.3 0.2 2.1 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK ACP53EA PF06313.11 KNZ79561.1 - 0.1 12.8 0.1 0.12 12.6 0.1 1.1 1 0 0 1 1 1 0 Drosophila ACP53EA protein RasGEF PF00617.19 KNZ79563.1 - 1.1e-33 117.0 0.1 1.8e-33 116.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KNZ79563.1 - 3e-08 33.8 0.0 8.8e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 KNZ79563.1 - 0.00019 21.1 0.1 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 Ras family Hormone_3 PF00159.18 KNZ79563.1 - 0.0065 16.5 0.3 2.1 8.5 0.0 2.9 3 0 0 3 3 3 2 Pancreatic hormone peptide Viral_helicase1 PF01443.18 KNZ79563.1 - 0.053 13.2 0.3 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SurE PF01975.17 KNZ79564.1 - 7.7e-40 136.8 0.0 9.9e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_hydro_16 PF00722.21 KNZ79565.1 - 1.2e-07 31.4 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ribosomal_L15e PF00827.17 KNZ79566.1 - 4.6e-79 264.6 11.8 2.5e-78 262.2 11.8 1.8 1 1 0 1 1 1 1 Ribosomal L15 Pex2_Pex12 PF04757.14 KNZ79568.1 - 1.1e-47 162.6 6.1 1.5e-47 162.1 6.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ank_2 PF12796.7 KNZ79568.1 - 3.9e-38 129.9 0.5 2.4e-14 53.7 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ79568.1 - 1.5e-27 95.6 2.5 1e-09 38.7 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 KNZ79568.1 - 2.8e-23 83.5 8.3 6.1e-08 33.0 1.0 3.2 1 1 1 3 3 3 3 SPX domain Ank PF00023.30 KNZ79568.1 - 6e-19 67.6 3.0 0.00018 21.8 0.1 6.5 5 1 1 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KNZ79568.1 - 3.2e-17 60.8 0.5 0.0016 18.7 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KNZ79568.1 - 2.7e-15 56.2 3.9 9.5e-05 22.6 0.0 4.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) GDPD PF03009.17 KNZ79568.1 - 6.9e-10 39.1 0.0 1.5e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family CCDC154 PF15450.6 KNZ79568.1 - 0.13 10.8 1.2 0.19 10.2 1.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Haem_degrading PF03928.14 KNZ79569.1 - 9.7e-11 41.8 0.0 2.4e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Haem-degrading SSB PF00436.25 KNZ79570.1 - 1.6e-15 57.0 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family GTP_EFTU PF00009.27 KNZ79571.1 - 4.8e-32 111.1 0.0 9.2e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KNZ79571.1 - 6.4e-11 42.5 0.0 2.4e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 KNZ79571.1 - 4.7e-10 39.6 0.2 1e-09 38.5 0.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 KNZ79571.1 - 0.007 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 KNZ79571.1 - 0.013 15.4 0.1 0.035 14.0 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 KNZ79571.1 - 0.028 14.8 0.2 0.072 13.5 0.2 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Na_Ca_ex PF01699.24 KNZ79572.1 - 1.1e-10 41.7 28.2 2.5e-08 34.0 8.2 2.7 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF1270 PF06900.11 KNZ79572.1 - 0.047 14.1 2.1 1.8 9.0 0.4 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) DUF962 PF06127.11 KNZ79572.1 - 0.64 10.1 4.3 16 5.7 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF962) Na_Ca_ex PF01699.24 KNZ79573.1 - 0.0006 19.8 4.6 0.00084 19.3 4.6 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF3792 PF12670.7 KNZ79573.1 - 0.063 13.4 3.8 0.098 12.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Acyltransferase PF01553.21 KNZ79574.1 - 1.2e-22 80.0 0.0 1.6e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase PIF1 PF05970.14 KNZ79576.1 - 1.5e-30 106.6 0.0 1.7e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase DUF2791 PF10923.8 KNZ79576.1 - 0.022 13.6 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Torsin PF06309.11 KNZ79576.1 - 0.039 14.1 0.1 0.063 13.4 0.1 1.3 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 KNZ79576.1 - 0.041 14.3 0.0 0.041 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ79576.1 - 0.042 13.6 0.2 0.046 13.4 0.2 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ79576.1 - 0.061 13.3 0.1 0.26 11.3 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KNZ79576.1 - 0.077 13.4 0.1 0.2 12.1 0.1 1.8 1 1 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 KNZ79576.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KNZ79576.1 - 0.19 11.3 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain POT1PC PF16686.5 KNZ79579.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein gag-asp_proteas PF13975.6 KNZ79580.1 - 6.9e-09 36.1 0.0 9.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ79580.1 - 6e-07 30.0 0.0 1e-06 29.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ79580.1 - 0.0081 16.0 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease GP120 PF00516.18 KNZ79581.1 - 0.24 9.9 0.4 0.35 9.4 0.4 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 Nucleoside_tran PF01733.18 KNZ79582.1 - 1.8e-35 122.8 13.9 1.8e-35 122.8 13.9 2.1 2 1 0 2 2 2 1 Nucleoside transporter PHB_acc PF05233.13 KNZ79582.1 - 0.24 11.4 1.1 32 4.6 0.0 3.0 3 0 0 3 3 3 0 PHB accumulation regulatory domain Integrase_H2C2 PF17921.1 KNZ79585.1 - 3.6e-11 43.0 1.3 7.3e-11 42.0 1.3 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain zf-H2C2 PF09337.10 KNZ79585.1 - 0.59 10.4 0.0 0.59 10.4 0.0 2.5 3 0 0 3 3 3 0 H2C2 zinc finger Chromo PF00385.24 KNZ79586.1 - 0.006 16.5 1.7 0.0084 16.0 1.7 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KNZ79586.1 - 0.037 13.9 2.0 0.06 13.2 0.1 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain MRC1 PF09444.10 KNZ79587.1 - 5.8e-25 88.5 23.6 5.8e-25 88.5 23.6 5.5 7 2 0 7 7 7 1 MRC1-like domain PAC1 PF16094.5 KNZ79587.1 - 0.15 11.2 2.4 0.41 9.8 2.4 1.8 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Ank_2 PF12796.7 KNZ79588.1 - 8e-18 64.8 0.0 3e-09 37.3 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ79588.1 - 3.6e-17 62.5 1.4 2.2e-09 37.7 0.0 4.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KNZ79588.1 - 4e-17 61.8 1.8 2e-06 28.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KNZ79588.1 - 2.5e-13 50.0 0.1 4.4e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ79588.1 - 5.4e-13 47.9 1.3 0.00013 22.1 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 KNZ79588.1 - 0.00039 20.3 0.1 0.0051 16.6 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain KxDL PF10241.9 KNZ79588.1 - 0.004 17.4 0.7 0.0094 16.2 0.1 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein Fur_reg_FbpB PF13040.6 KNZ79588.1 - 0.1 12.2 0.5 0.23 11.0 0.5 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein B Cortex-I_coil PF09304.10 KNZ79588.1 - 0.62 10.3 3.8 1.8 8.8 3.8 1.8 1 0 0 1 1 1 0 Cortexillin I, coiled coil Rab5-bind PF09311.11 KNZ79588.1 - 0.94 8.8 5.1 2.3 7.5 0.2 2.4 1 1 0 2 2 2 0 Rabaptin-like protein Glyco_hydro_3_C PF01915.22 KNZ79589.1 - 9.4e-46 156.3 0.0 1.4e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ79589.1 - 2.6e-08 33.6 0.0 4.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ79589.1 - 0.00016 21.7 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 KNZ79589.1 - 0.067 12.2 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain p450 PF00067.22 KNZ79591.1 - 2.1e-64 218.0 0.0 3e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Shal-type PF11601.8 KNZ79591.1 - 0.048 13.2 0.4 0.17 11.5 0.4 2.0 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal UbiA PF01040.18 KNZ79592.1 - 2e-47 161.6 18.4 2.6e-47 161.2 18.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 KNZ79593.1 - 3.1e-17 62.5 0.0 3.3e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 An_peroxidase PF03098.15 KNZ79596.1 - 1.9e-32 112.5 0.0 1.2e-18 67.0 0.0 3.3 1 1 2 3 3 3 3 Animal haem peroxidase Synaptobrevin PF00957.21 KNZ79597.1 - 2.1e-14 53.1 0.7 3.5e-14 52.4 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 KNZ79597.1 - 3e-13 49.6 0.0 5.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MIS13 PF08202.11 KNZ79597.1 - 0.089 12.1 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Actin PF00022.19 KNZ79598.1 - 0.0022 16.7 0.0 0.02 13.5 0.0 2.1 1 1 2 3 3 3 2 Actin Tetraspanin PF00335.20 KNZ79599.1 - 0.017 14.8 11.0 0.074 12.7 11.0 2.1 1 1 0 1 1 1 0 Tetraspanin family Mannosyl_trans2 PF04188.13 KNZ79600.1 - 3.2e-08 33.3 3.9 0.00094 18.6 1.5 2.1 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) RVT_1 PF00078.27 KNZ79600.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) NAAA-beta PF15508.6 KNZ79601.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Pox_P21 PF05313.12 KNZ79602.1 - 0.00099 18.7 5.1 0.0011 18.6 4.3 1.4 1 1 0 1 1 1 1 Poxvirus P21 membrane protein Rapsyn_N PF10579.9 KNZ79602.1 - 0.16 12.1 0.4 0.41 10.8 0.1 1.7 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region ING PF12998.7 KNZ79604.1 - 0.00044 20.8 0.5 0.00074 20.1 0.5 1.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1712 PF08217.11 KNZ79607.1 - 1.5e-16 60.1 0.0 2e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) ASXH PF13919.6 KNZ79607.1 - 0.23 11.5 0.2 0.53 10.3 0.2 1.5 1 0 0 1 1 1 0 Asx homology domain zf-CCCH PF00642.24 KNZ79608.1 - 1.5e-11 43.9 22.2 7.5e-06 25.7 1.3 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNZ79608.1 - 0.00024 21.1 26.3 1.3 9.2 0.6 5.9 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 KNZ79608.1 - 0.0053 17.0 10.9 0.15 12.3 4.4 3.5 1 1 2 3 3 3 2 Zinc-finger containing family Usp PF00582.26 KNZ79608.1 - 0.064 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Universal stress protein family zf-CCCH_4 PF18044.1 KNZ79608.1 - 4 7.3 26.9 0.36 10.7 0.9 4.8 6 0 0 6 6 6 0 CCCH-type zinc finger zf-C3H1 PF10650.9 KNZ79608.1 - 7.6 6.4 8.0 91 2.9 0.2 3.8 3 0 0 3 3 3 0 Putative zinc-finger domain DnaJ-X PF14308.6 KNZ79609.1 - 7.7e-59 198.7 0.1 7.7e-59 198.7 0.1 2.3 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KNZ79609.1 - 2.5e-07 30.7 2.1 4e-07 30.1 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain rRNA_processing PF08524.11 KNZ79609.1 - 0.91 9.5 19.2 0.15 12.1 4.2 2.6 2 0 0 2 2 2 0 rRNA processing PIF1 PF05970.14 KNZ79614.1 - 4.3e-52 177.5 0.1 1.3e-47 162.7 0.2 2.1 1 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KNZ79614.1 - 5.3e-20 71.9 0.0 8.3e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ79614.1 - 3.8e-09 37.0 0.0 9.4e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNZ79614.1 - 1.3e-05 25.5 0.1 3.6e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KNZ79614.1 - 0.00054 19.3 1.1 0.031 13.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 KNZ79614.1 - 0.00084 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region NTPase_1 PF03266.15 KNZ79614.1 - 0.0015 18.4 0.4 0.42 10.5 0.1 2.4 2 0 0 2 2 2 1 NTPase Mg_chelatase PF01078.21 KNZ79614.1 - 0.0025 17.2 0.1 0.0062 15.9 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KNZ79614.1 - 0.0029 18.0 0.2 0.0099 16.3 0.1 1.9 1 1 1 2 2 1 1 AAA ATPase domain AAA PF00004.29 KNZ79614.1 - 0.0038 17.7 0.1 0.007 16.8 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KNZ79614.1 - 0.0066 16.5 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KNZ79614.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.14 KNZ79614.1 - 0.0095 15.9 0.7 0.062 13.3 0.2 2.6 2 2 1 3 3 2 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 KNZ79614.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KNZ79614.1 - 0.02 14.8 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 KNZ79614.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 KNZ79614.1 - 0.054 13.9 1.6 0.53 10.7 0.0 2.9 3 1 0 3 3 3 0 RNA helicase DEAD PF00270.29 KNZ79614.1 - 0.054 13.3 0.1 10 5.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_29 PF13555.6 KNZ79614.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KNZ79614.1 - 0.1 12.4 3.7 0.19 11.4 0.9 2.8 2 1 0 2 2 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 KNZ79614.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 KNZ79614.1 - 0.12 12.3 0.1 0.36 10.7 0.1 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AbfS_sensor PF18225.1 KNZ79614.1 - 0.13 12.2 0.4 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain ABC_tran PF00005.27 KNZ79614.1 - 0.16 12.5 0.2 0.52 10.8 0.1 1.8 1 1 0 1 1 1 0 ABC transporter RhoGAP PF00620.27 KNZ79615.1 - 3.1e-40 137.5 0.1 1.2e-39 135.5 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 KNZ79615.1 - 2.4e-07 31.0 1.8 6.6e-07 29.5 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PIN_12 PF16289.5 KNZ79615.1 - 0.044 14.3 0.8 0.13 12.7 0.8 1.7 1 0 0 1 1 1 0 PIN domain RGS PF00615.19 KNZ79615.1 - 0.62 10.3 3.7 5.1 7.4 2.7 2.7 2 1 0 2 2 2 0 Regulator of G protein signaling domain ABC_membrane PF00664.23 KNZ79616.1 - 4.8e-49 167.5 28.3 8.3e-26 91.2 7.9 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ79616.1 - 4.4e-46 156.8 0.0 6.1e-27 94.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ79616.1 - 3.6e-11 42.9 4.6 0.0064 15.9 0.1 4.2 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KNZ79616.1 - 1.8e-06 28.6 0.4 0.001 19.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KNZ79616.1 - 3.3e-06 27.6 0.2 0.1 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KNZ79616.1 - 1.2e-05 24.9 0.0 0.036 13.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 KNZ79616.1 - 6e-05 23.0 7.2 0.0082 16.0 0.4 4.2 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 KNZ79616.1 - 0.00016 21.9 0.1 0.032 14.3 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 KNZ79616.1 - 0.00027 20.1 0.0 0.047 12.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KNZ79616.1 - 0.0004 20.0 0.0 1.3 8.6 0.0 2.6 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 KNZ79616.1 - 0.00067 19.7 0.2 0.68 10.0 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ79616.1 - 0.0012 18.7 0.0 0.43 10.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KNZ79616.1 - 0.0025 18.1 0.1 0.56 10.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KNZ79616.1 - 0.0032 17.0 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KNZ79616.1 - 0.0032 16.9 0.1 0.75 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 KNZ79616.1 - 0.0038 16.1 0.1 0.4 9.4 0.0 2.8 3 0 0 3 3 3 1 Adenovirus IVa2 protein AAA_5 PF07728.14 KNZ79616.1 - 0.0094 16.0 0.6 7.9 6.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KNZ79616.1 - 0.03 14.1 0.0 6.8 6.4 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 KNZ79616.1 - 0.03 14.1 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_15 PF13175.6 KNZ79616.1 - 0.03 14.0 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Pox_A32 PF04665.12 KNZ79616.1 - 0.036 13.5 0.3 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein Roc PF08477.13 KNZ79616.1 - 0.042 14.1 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KNZ79616.1 - 0.053 13.4 0.1 0.64 9.9 0.0 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea DEAD PF00270.29 KNZ79616.1 - 0.054 13.3 0.0 15 5.3 0.1 2.9 2 1 0 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 KNZ79616.1 - 0.055 13.5 0.8 5.7 7.0 0.0 2.7 2 0 0 2 2 2 0 Dynamin family ResIII PF04851.15 KNZ79616.1 - 0.066 13.2 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.9 KNZ79616.1 - 0.11 12.3 0.1 6.7 6.5 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 KNZ79616.1 - 0.11 11.9 0.0 4.3 6.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 KNZ79616.1 - 0.11 13.0 0.0 23 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 KNZ79616.1 - 0.17 12.3 0.1 2 8.9 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KNZ79616.1 - 0.21 11.2 1.3 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 KNZ79616.1 - 0.3 9.8 1.0 4.9 5.8 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RRM_1 PF00076.22 KNZ79617.1 - 1.7e-13 50.2 0.1 2.5e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 KNZ79617.1 - 8.4e-09 35.1 2.7 1.6e-08 34.3 2.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ79617.1 - 7e-05 22.7 0.0 0.00027 20.9 0.0 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 KNZ79617.1 - 0.0014 18.3 2.3 0.0044 16.7 2.3 1.9 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 KNZ79617.1 - 0.05 13.4 1.4 0.05 13.4 1.4 2.1 2 0 0 2 2 2 0 Zinc knuckle RRM_7 PF16367.5 KNZ79617.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif Glyco_hydro_72 PF03198.14 KNZ79618.1 - 1.3e-92 310.4 0.5 1.3e-92 310.4 0.5 1.4 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 KNZ79618.1 - 1.6e-18 67.1 0.5 4.5e-18 65.7 0.5 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 KNZ79618.1 - 0.025 14.0 0.1 0.068 12.6 0.1 1.7 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) SUR7 PF06687.12 KNZ79619.1 - 4.1e-08 33.1 12.3 7.8e-08 32.2 11.4 1.8 1 1 0 1 1 1 1 SUR7/PalI family DUF2231 PF09990.9 KNZ79619.1 - 0.24 11.9 4.8 1.5 9.3 4.3 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) TssN PF17555.2 KNZ79619.1 - 4.5 6.6 6.2 7.2 5.9 6.2 1.3 1 1 0 1 1 1 0 Type VI secretion system, TssN Glyco_transf_28 PF03033.20 KNZ79620.1 - 9.2e-30 103.5 0.0 1.8e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KNZ79620.1 - 4.7e-23 81.3 0.9 6.2e-14 51.8 0.1 3.4 3 0 0 3 3 3 3 GRAM domain PH PF00169.29 KNZ79620.1 - 8e-15 55.2 0.4 2.3e-13 50.6 0.2 2.6 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 KNZ79620.1 - 5.2e-06 26.7 0.1 2.1e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KNZ79620.1 - 3e-05 24.4 1.3 0.11 12.9 0.5 2.6 1 1 1 2 2 2 2 Pleckstrin homology domain UDPGT PF00201.18 KNZ79620.1 - 0.00016 20.6 0.0 0.00038 19.4 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_3 PF14593.6 KNZ79620.1 - 0.0025 17.9 0.1 0.0051 16.9 0.1 1.5 1 0 0 1 1 1 1 PH domain DIOX_N PF14226.6 KNZ79621.1 - 2.7e-05 24.9 0.0 5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ79621.1 - 0.002 18.6 0.0 0.0064 17.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIC1 PF07064.13 KNZ79622.1 - 2.1e-96 322.2 0.0 3.2e-96 321.6 0.0 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 KNZ79622.1 - 0.0016 18.7 0.0 2.3 8.6 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 KNZ79622.1 - 0.011 16.0 0.2 0.64 10.4 0.0 3.2 3 0 0 3 3 3 0 Kelch motif PD40 PF07676.12 KNZ79622.1 - 0.033 14.1 2.3 1.2 9.2 0.5 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PRELI PF04707.14 KNZ79623.1 - 6.1e-13 48.9 0.0 7.6e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Lactamase_B_2 PF12706.7 KNZ79624.1 - 2.5e-15 56.5 0.0 2.3e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MMR_HSR1_Xtn PF16897.5 KNZ79625.1 - 5.4e-34 116.4 1.3 1e-33 115.5 1.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KNZ79625.1 - 7.7e-20 71.1 0.0 1.5e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KNZ79625.1 - 1.1e-18 67.1 0.0 1.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 KNZ79625.1 - 2.7e-10 40.0 0.0 4.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KNZ79625.1 - 0.0021 18.1 0.2 0.12 12.4 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MeaB PF03308.16 KNZ79625.1 - 0.023 13.7 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 KNZ79625.1 - 0.03 13.4 0.0 0.066 12.3 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 KNZ79625.1 - 0.072 13.5 0.1 0.16 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 KNZ79626.1 - 9.2e-65 218.6 0.0 1.6e-64 217.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79626.1 - 1.8e-34 119.2 0.0 7.9e-26 90.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79626.1 - 0.00013 21.4 1.5 0.00092 18.6 0.6 2.5 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 KNZ79626.1 - 0.002 17.3 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 KNZ79626.1 - 0.0026 17.7 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 KNZ79626.1 - 0.0083 15.8 0.2 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KNZ79626.1 - 0.075 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family B-block_TFIIIC PF04182.12 KNZ79627.1 - 5.1e-07 29.8 0.1 5.3e-05 23.3 0.0 3.1 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KNZ79627.1 - 0.076 12.9 0.1 7.4 6.5 0.0 3.0 3 0 0 3 3 3 0 MarR family HTH_27 PF13463.6 KNZ79627.1 - 0.12 12.9 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 0 Winged helix DNA-binding domain PRELI PF04707.14 KNZ79628.1 - 1.2e-34 119.4 0.0 1.5e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family Peptidase_M28 PF04389.17 KNZ79629.1 - 8.2e-31 107.2 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KNZ79629.1 - 0.0034 17.1 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KNZ79629.1 - 0.0058 15.7 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase ABC_membrane_2 PF06472.15 KNZ79630.1 - 1.6e-79 267.2 4.3 2.2e-79 266.6 4.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KNZ79630.1 - 2.2e-16 60.6 0.0 5.4e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KNZ79630.1 - 0.0002 21.3 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KNZ79630.1 - 0.0098 16.4 0.0 0.0098 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ79630.1 - 0.021 15.2 1.3 0.35 11.2 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 KNZ79630.1 - 0.033 13.6 0.0 0.088 12.2 0.1 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KNZ79630.1 - 0.035 13.9 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KNZ79630.1 - 0.036 14.0 0.5 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_27 PF13514.6 KNZ79630.1 - 0.095 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KNZ79630.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_15 PF13175.6 KNZ79630.1 - 0.18 11.5 0.2 0.45 10.2 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain NT5C PF06941.12 KNZ79631.1 - 8.5e-09 35.5 0.2 4.8e-08 33.1 0.2 2.1 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 KNZ79631.1 - 5.3e-06 26.6 0.1 2e-05 24.7 0.1 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ79631.1 - 9e-06 26.1 0.0 2.5e-05 24.7 0.0 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 KNZ79631.1 - 4.2e-05 23.3 0.0 6.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KNZ79631.1 - 0.052 14.0 0.0 0.076 13.4 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 KNZ79631.1 - 0.098 12.8 0.2 0.37 10.9 0.0 1.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Pro_CA PF00484.19 KNZ79632.1 - 3.2e-14 53.5 0.1 4.3e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase RINT1_TIP1 PF04437.13 KNZ79633.1 - 1.4e-95 321.1 0.3 4.5e-95 319.4 0.0 1.8 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Rbsn PF11464.8 KNZ79633.1 - 0.11 12.2 0.3 0.44 10.3 0.3 2.0 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Nnf1 PF03980.14 KNZ79633.1 - 5 7.5 8.7 0.71 10.3 0.7 3.1 2 1 1 3 3 3 0 Nnf1 Pkinase_Tyr PF07714.17 KNZ79634.1 - 9.9e-22 77.5 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ79634.1 - 1.4e-17 63.9 0.0 2.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain NTase_sub_bind PF08780.11 KNZ79634.1 - 0.02 14.9 0.2 0.054 13.5 0.2 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like MCM PF00493.23 KNZ79635.1 - 9.3e-96 319.2 0.0 1.5e-95 318.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KNZ79635.1 - 5.6e-34 116.7 0.0 1.4e-33 115.4 0.0 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 KNZ79635.1 - 2.3e-22 79.2 0.2 4.1e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KNZ79635.1 - 5.5e-15 55.8 0.6 1.4e-14 54.6 0.6 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KNZ79635.1 - 9.9e-08 31.6 0.1 1.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KNZ79635.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNZ79635.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 KNZ79635.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 KNZ79636.1 - 2e-32 110.7 14.7 3.5e-08 34.0 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79636.1 - 8.8e-10 38.8 0.2 0.14 12.5 0.0 4.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KNZ79636.1 - 0.00087 17.9 0.0 0.61 8.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PQQ_2 PF13360.6 KNZ79636.1 - 0.01 15.4 0.0 1.9 8.0 0.0 2.7 2 1 0 2 2 2 0 PQQ-like domain Myb_DNA-binding PF00249.31 KNZ79637.1 - 2.6e-37 126.8 5.5 6.3e-14 51.9 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ79637.1 - 6.6e-33 112.8 0.3 1.8e-16 60.1 0.0 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 KNZ79637.1 - 4.8e-05 23.4 0.0 2.5 8.2 0.0 3.3 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 KNZ79637.1 - 0.00062 19.9 0.3 0.93 9.7 0.0 2.8 3 0 0 3 3 3 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 KNZ79637.1 - 0.0065 16.5 0.1 10 6.3 0.0 3.2 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 KNZ79637.1 - 0.011 15.6 0.0 8.8 6.3 0.0 2.9 2 1 1 3 3 3 0 Myb DNA-binding like SGTA_dimer PF16546.5 KNZ79638.1 - 1.2e-26 92.3 0.6 2.4e-26 91.3 0.6 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 KNZ79638.1 - 4.9e-25 86.3 0.9 1.2e-07 31.3 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ79638.1 - 3.5e-21 73.5 0.4 3.2e-06 26.8 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ79638.1 - 1.9e-18 65.9 2.9 7e-09 35.2 0.3 3.8 3 1 1 4 4 4 3 TPR repeat TPR_8 PF13181.6 KNZ79638.1 - 3e-17 61.3 1.0 1.1e-06 28.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ79638.1 - 5.2e-14 51.8 0.1 7.9e-05 23.2 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ79638.1 - 4.7e-11 42.3 1.7 0.0018 18.5 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ79638.1 - 1.8e-10 41.3 4.7 2.9e-06 27.8 0.1 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ79638.1 - 2.6e-08 34.0 2.6 0.00065 19.9 0.5 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ79638.1 - 3e-07 30.0 0.3 0.00022 21.0 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ79638.1 - 7.6e-07 29.5 1.1 0.00064 20.2 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ79638.1 - 2.1e-05 24.2 3.3 0.4 10.6 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat STI1 PF17830.1 KNZ79638.1 - 4.9e-05 23.2 12.4 0.0058 16.5 3.1 3.3 2 1 1 3 3 3 2 STI1 domain TPR_9 PF13371.6 KNZ79638.1 - 6.9e-05 22.9 0.0 0.007 16.5 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ79638.1 - 7.5e-05 23.1 0.3 0.092 13.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ79638.1 - 0.00038 19.8 0.3 0.028 13.6 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 KNZ79638.1 - 0.0023 18.4 0.0 0.16 12.4 0.0 2.3 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 KNZ79638.1 - 0.19 12.4 1.5 7 7.6 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 KNZ79638.1 - 0.81 9.4 5.6 9.2 5.9 0.4 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Prp19 PF08606.11 KNZ79639.1 - 5.4e-32 109.6 3.2 1.1e-31 108.6 3.2 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 KNZ79639.1 - 2.5e-09 37.3 0.0 0.00029 21.1 0.0 4.4 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ79639.1 - 3.3e-07 30.9 3.4 0.0065 17.3 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat U-box PF04564.15 KNZ79639.1 - 0.00019 21.5 0.0 0.00068 19.8 0.0 1.9 2 0 0 2 2 2 1 U-box domain Frtz PF11768.8 KNZ79639.1 - 0.0078 14.6 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz zf-Nse PF11789.8 KNZ79639.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OPT PF03169.15 KNZ79640.1 - 6.7e-188 626.2 59.5 7.7e-188 626.0 59.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ESSS PF10183.9 KNZ79640.1 - 0.13 12.5 0.8 1.6 9.0 0.1 2.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2418 PF10332.9 KNZ79640.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2418) TauD PF02668.16 KNZ79641.1 - 2e-55 188.5 1.2 2.5e-55 188.2 1.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_3 PF07732.15 KNZ79641.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase DIE2_ALG10 PF04922.12 KNZ79642.1 - 2.8e-119 398.9 9.0 3.3e-119 398.7 9.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Spc7 PF08317.11 KNZ79644.1 - 5.6e-85 285.0 6.6 8.4e-85 284.4 6.6 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KNZ79644.1 - 1.3e-07 31.5 0.1 3.9e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Spc7_C2 DUF3921 PF13060.6 KNZ79644.1 - 0.11 12.5 0.3 0.35 10.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) ATPase PF06745.13 KNZ79644.1 - 0.13 11.5 1.0 0.31 10.4 1.0 1.5 1 0 0 1 1 1 0 KaiC Fez1 PF06818.15 KNZ79644.1 - 0.88 10.0 8.4 3.2 8.2 8.4 2.0 1 0 0 1 1 1 0 Fez1 SlyX PF04102.12 KNZ79644.1 - 0.96 10.1 5.7 1.9 9.2 3.0 2.9 2 0 0 2 2 2 0 SlyX Kinesin PF00225.23 KNZ79645.1 - 9.1e-79 264.8 0.0 1.5e-78 264.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ79645.1 - 1.3e-15 57.6 0.0 3.6e-12 46.5 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding DUF957 PF06117.11 KNZ79645.1 - 0.15 11.6 0.1 0.45 10.1 0.1 1.8 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Mito_carr PF00153.27 KNZ79647.1 - 1.3e-17 63.5 0.0 3.8e-07 29.9 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein C2 PF00168.30 KNZ79648.1 - 3.4e-92 303.5 1.7 6.4e-21 74.6 0.0 5.5 5 0 0 5 5 5 5 C2 domain MFS_1 PF07690.16 KNZ79648.1 - 0.11 11.5 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily MLVIN_C PF18697.1 KNZ79648.1 - 1.1 9.5 3.1 19 5.4 0.0 3.1 3 0 0 3 3 3 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Tfb2 PF03849.14 KNZ79649.1 - 7.3e-133 442.9 0.0 8.5e-133 442.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KNZ79649.1 - 1e-24 86.7 0.0 1.8e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KNZ79649.1 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MTS PF05175.14 KNZ79650.1 - 9.8e-09 35.0 0.0 8e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 KNZ79650.1 - 0.017 15.9 0.0 0.069 13.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 KNZ79650.1 - 0.024 14.3 0.0 0.064 12.9 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KNZ79650.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain C2 PF00168.30 KNZ79651.1 - 2.1e-20 72.9 0.0 5.5e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 C2 domain NUDIX PF00293.28 KNZ79652.1 - 1.5e-05 25.1 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NPL4 PF05021.15 KNZ79653.1 - 2.9e-99 332.3 0.0 3.6e-99 332.0 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KNZ79653.1 - 1.8e-61 206.6 0.0 2.7e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KNZ79653.1 - 7.2e-06 26.4 0.0 1.7e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RanBP PF00641.18 KNZ79653.1 - 3.2 7.1 7.6 0.07 12.5 1.1 1.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others bZIP_2 PF07716.15 KNZ79654.1 - 9.1e-09 35.3 13.0 3e-08 33.6 11.5 2.4 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 KNZ79654.1 - 0.00014 21.8 8.0 0.00041 20.4 8.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor V_ATPase_I PF01496.19 KNZ79654.1 - 0.69 7.8 3.4 0.84 7.5 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CHCH PF06747.13 KNZ79655.1 - 4.9e-05 23.3 4.8 0.0001 22.3 4.7 1.6 1 1 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 KNZ79655.1 - 0.00098 18.8 1.3 0.0012 18.5 1.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 KNZ79655.1 - 0.0022 18.0 3.3 0.0032 17.5 3.3 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 KNZ79655.1 - 0.0042 17.5 1.5 0.0067 16.8 1.5 1.3 1 0 0 1 1 1 1 GCK domain Pet191_N PF10203.9 KNZ79655.1 - 0.005 17.1 4.7 0.025 14.9 4.8 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 KNZ79655.1 - 0.12 12.7 5.6 0.38 11.1 1.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GDPD PF03009.17 KNZ79656.1 - 1e-30 107.4 0.0 1.6e-25 90.3 0.0 2.3 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 KNZ79656.1 - 1e-05 25.8 1.2 0.0012 19.3 0.7 2.4 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family UCR_TM PF02921.14 KNZ79657.1 - 3.7e-11 43.3 2.8 1.3e-10 41.6 2.8 1.9 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KNZ79657.1 - 2.7e-10 40.0 0.0 4.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4149 PF13664.6 KNZ79658.1 - 5.8e-22 77.9 5.9 1.4e-21 76.7 5.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) PY_rept_46 PF09689.10 KNZ79658.1 - 0.16 12.5 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Plasmodium yoelii repeat (PY_rept_46) LRR_9 PF14580.6 KNZ79659.1 - 1.4e-61 207.0 0.2 3.5e-61 205.7 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 KNZ79659.1 - 7.6e-08 32.5 15.4 3.1e-05 24.2 3.6 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KNZ79659.1 - 9.7e-08 31.7 2.9 2.8e-07 30.2 2.9 1.9 1 0 0 1 1 1 1 Leucine rich repeat Syja_N PF02383.18 KNZ79660.1 - 1.1e-87 294.3 0.3 1.4e-87 294.0 0.3 1.1 1 0 0 1 1 1 1 SacI homology domain NAP PF00956.18 KNZ79661.1 - 2.7e-22 79.2 4.4 2.5e-21 76.0 4.4 2.2 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Polysacc_deac_1 PF01522.21 KNZ79662.1 - 4.5e-31 107.3 0.0 8.2e-31 106.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 KNZ79662.1 - 0.0095 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Pkinase PF00069.25 KNZ79663.1 - 3.7e-42 144.5 0.0 1.1e-20 74.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79663.1 - 3.1e-12 46.3 0.0 1e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ79663.1 - 0.0015 17.4 0.2 0.0036 16.1 0.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase SR-25 PF10500.9 KNZ79663.1 - 0.62 9.6 7.2 1.2 8.6 7.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 KNZ79664.1 - 1.1e-51 175.8 0.0 1.5e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79664.1 - 4.3e-38 131.1 0.0 6.2e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ79664.1 - 2.2e-08 33.3 0.2 4.8e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KNZ79664.1 - 0.015 14.6 0.0 0.033 13.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 KNZ79664.1 - 0.026 14.4 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ndc1_Nup PF09531.10 KNZ79664.1 - 5.9 5.5 12.8 8.3 5.0 12.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MitMem_reg PF13012.6 KNZ79665.1 - 3.4e-25 88.6 0.2 5.5e-25 88.0 0.2 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function MCM PF00493.23 KNZ79666.1 - 1.2e-103 345.1 0.1 7.3e-103 342.5 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KNZ79666.1 - 2.8e-34 117.7 0.0 6.1e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KNZ79666.1 - 1.6e-29 102.2 1.0 3.6e-29 101.0 1.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KNZ79666.1 - 4e-15 56.3 0.0 9.8e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KNZ79666.1 - 1.3e-06 27.9 0.0 0.00048 19.6 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KNZ79666.1 - 5.1e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KNZ79666.1 - 0.00025 20.9 0.2 0.0012 18.7 0.1 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 KNZ79666.1 - 0.01 16.4 0.7 0.22 12.2 0.1 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal AAA PF00004.29 KNZ79666.1 - 0.061 13.7 0.2 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.26 KNZ79667.1 - 7.1e-08 32.5 19.0 1.7e-06 28.1 0.6 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ79667.1 - 1.9e-06 28.2 14.2 0.0019 18.9 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf_ZIC PF18366.1 KNZ79667.1 - 0.0042 17.2 1.6 2.3 8.4 0.4 2.6 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf-C2H2_6 PF13912.6 KNZ79667.1 - 0.006 16.5 13.2 0.0097 15.9 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KNZ79667.1 - 0.0069 16.8 14.1 0.034 14.6 2.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KNZ79667.1 - 0.02 15.1 4.6 0.054 13.8 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KNZ79667.1 - 0.59 9.9 8.0 4.5 7.1 0.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2235 PF09994.9 KNZ79668.1 - 0.013 14.8 1.2 0.016 14.6 0.4 1.3 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) KCNQ2_u3 PF16642.5 KNZ79668.1 - 0.2 12.7 6.7 0.53 11.3 6.7 1.7 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Integrase_H2C2 PF17921.1 KNZ79669.1 - 2.5e-16 59.5 0.2 4.1e-16 58.8 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 KNZ79669.1 - 0.00081 19.6 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Methyltransf_2 PF00891.18 KNZ79671.1 - 1.6e-12 47.1 0.2 8.3e-10 38.3 0.0 3.1 3 0 0 3 3 3 2 O-methyltransferase domain RRM_1 PF00076.22 KNZ79672.1 - 0.0044 16.8 0.1 0.42 10.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lectin_N PF03954.14 KNZ79673.1 - 0.18 11.5 1.7 0.66 9.7 0.5 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain RRM_1 PF00076.22 KNZ79674.1 - 6.5e-07 29.1 0.0 0.022 14.5 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SprA-related PF12118.8 KNZ79674.1 - 0.037 13.2 2.6 0.049 12.8 2.6 1.2 1 0 0 1 1 1 0 SprA-related family Cep57_CLD_2 PF14197.6 KNZ79674.1 - 0.058 13.5 9.8 0.35 11.0 4.9 3.0 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 CCDC-167 PF15188.6 KNZ79674.1 - 0.32 11.4 5.0 0.25 11.7 2.3 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Rad17 PF03215.15 KNZ79675.1 - 2.8e-24 86.1 0.0 8.1e-24 84.6 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KNZ79675.1 - 0.00013 22.4 0.0 0.00025 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ79675.1 - 0.00017 22.0 0.2 0.001 19.5 0.1 2.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_6 PF12774.7 KNZ79675.1 - 0.0012 17.9 0.2 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KNZ79675.1 - 0.0012 19.1 0.0 0.0046 17.2 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_30 PF13604.6 KNZ79675.1 - 0.0031 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 KNZ79675.1 - 0.0048 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_18 PF13238.6 KNZ79675.1 - 0.012 16.2 0.0 0.039 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KNZ79675.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ79675.1 - 0.16 12.3 0.2 0.73 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase TsaE PF02367.17 KNZ79675.1 - 0.19 11.8 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Epimerase PF01370.21 KNZ79678.1 - 1.8e-20 73.4 0.2 1.2e-19 70.8 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ79678.1 - 4.3e-12 45.6 0.0 9.2e-12 44.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ79678.1 - 7.7e-11 42.2 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KNZ79678.1 - 1.8e-10 40.5 0.0 6.1e-06 25.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 KNZ79678.1 - 7.1e-10 38.8 0.0 1.4e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KNZ79678.1 - 0.016 14.7 0.0 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family HAD_SAK_2 PF18143.1 KNZ79678.1 - 0.054 13.8 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Polysacc_synt_2 PF02719.15 KNZ79678.1 - 0.12 11.5 0.1 0.21 10.7 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein UBX PF00789.20 KNZ79682.1 - 2e-09 37.5 0.0 6.3e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 KNZ79682.1 - 1.3e-06 28.2 0.0 2.4e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Mitofilin PF09731.9 KNZ79682.1 - 3 6.6 12.2 4.1 6.1 12.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIE_alpha PF02002.17 KNZ79683.1 - 8.7e-18 64.1 0.2 1.9e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 KNZ79683.1 - 2.1e-05 23.9 1.0 5.2e-05 22.7 1.0 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIE-A_C PF11521.8 KNZ79683.1 - 0.00029 21.1 0.0 0.0014 18.9 0.0 2.1 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha RecO_N_2 PF13114.6 KNZ79683.1 - 0.0015 18.2 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 RecO N terminal YppF PF14178.6 KNZ79683.1 - 0.088 12.7 0.0 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 YppF-like protein DZR PF12773.7 KNZ79683.1 - 0.11 12.5 0.2 0.21 11.6 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 KNZ79683.1 - 0.27 11.2 2.5 9.2 6.3 0.0 2.5 1 1 1 2 2 2 0 PhnA Zinc-Ribbon zf_UBZ PF18439.1 KNZ79683.1 - 0.29 10.8 1.0 2.5 7.7 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ThiF PF00899.21 KNZ79684.1 - 2.7e-11 43.3 0.0 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 ThiF family 3-HAO PF06052.12 KNZ79686.1 - 1.1e-57 193.9 0.0 1.2e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 KNZ79686.1 - 4.4e-06 26.3 0.0 7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KNZ79686.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Cupin AraC_binding PF02311.19 KNZ79686.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 KNZ79686.1 - 0.067 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Med6 PF04934.14 KNZ79688.1 - 7.1e-40 135.9 0.1 1.2e-39 135.2 0.1 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component Clat_adaptor_s PF01217.20 KNZ79689.1 - 7.4e-38 129.7 0.1 1.2e-37 129.0 0.1 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain ATP-synt_F PF01990.17 KNZ79690.1 - 9.2e-34 115.7 0.1 1.1e-33 115.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.6 KNZ79690.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PIN_8 PF18476.1 KNZ79690.1 - 0.019 14.8 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 PIN like domain AhpC-TSA PF00578.21 KNZ79690.1 - 0.032 14.1 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family UvrC_HhH_N PF08459.11 KNZ79690.1 - 0.04 13.8 0.0 0.04 13.8 0.0 1.1 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal Histone PF00125.24 KNZ79691.1 - 1e-48 165.0 3.8 1.9e-48 164.1 3.8 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TIM21 PF08294.11 KNZ79691.1 - 1.1e-19 70.8 0.0 3.3e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 TIM21 CENP-T_C PF15511.6 KNZ79691.1 - 0.00016 21.8 0.2 0.00032 20.8 0.2 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KNZ79691.1 - 0.00023 21.5 0.1 0.00047 20.5 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KNZ79691.1 - 0.00081 20.0 3.5 0.0018 18.9 3.5 1.5 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 KNZ79691.1 - 0.0064 16.7 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GBP_PSP PF02425.15 KNZ79691.1 - 0.45 10.2 1.7 19 5.0 0.2 2.5 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide Chalcone_2 PF16035.5 KNZ79692.1 - 1.5e-27 96.7 0.4 1.3e-15 57.7 0.0 2.3 1 1 1 2 2 2 2 Chalcone isomerase like PhyH PF05721.13 KNZ79692.1 - 0.02 15.2 0.0 0.28 11.4 0.0 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Chalcone_3 PF16036.5 KNZ79692.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Chalcone isomerase-like BLM10_mid PF16507.5 KNZ79693.1 - 4.2e-171 570.1 0.1 2.6e-99 333.3 0.0 2.4 1 1 1 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KNZ79693.1 - 9.7e-23 79.9 0.0 5.3e-22 77.5 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KNZ79693.1 - 1.4e-05 24.9 4.6 0.0017 18.4 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat BLM10_N PF16547.5 KNZ79693.1 - 0.0024 18.1 0.7 0.0088 16.3 0.1 2.2 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT_2 PF13646.6 KNZ79693.1 - 0.0026 18.1 3.3 0.012 16.0 0.1 3.7 4 0 0 4 4 4 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KNZ79693.1 - 0.0086 16.7 0.0 0.12 13.0 0.0 2.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KNZ79693.1 - 0.055 14.0 0.3 2.5 8.7 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat MatE PF01554.18 KNZ79693.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 MatE Nup54_57_C PF18570.1 KNZ79693.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain zf-CCCH PF00642.24 KNZ79694.1 - 2.2e-19 68.9 14.4 4.7e-11 42.3 2.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KNZ79694.1 - 1.9e-09 37.2 13.6 1.2e-06 28.4 3.8 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 KNZ79694.1 - 3.8e-07 29.7 11.4 3.3e-05 23.6 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KNZ79694.1 - 0.024 15.1 8.4 0.086 13.3 0.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 KNZ79694.1 - 0.04 14.6 9.7 0.53 11.0 1.7 2.7 1 1 1 2 2 2 0 Torus domain Choline_kinase PF01633.20 KNZ79695.1 - 1.3e-49 168.6 0.0 1.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KNZ79695.1 - 6.3e-11 42.6 0.0 9.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ATP_sub_h PF10775.9 KNZ79695.1 - 0.17 11.9 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 ATP synthase complex subunit h zf-CCHC PF00098.23 KNZ79696.1 - 0.0034 17.4 2.3 0.0034 17.4 2.3 3.2 3 0 0 3 3 3 1 Zinc knuckle DUF1870 PF08965.10 KNZ79696.1 - 0.13 12.3 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) PIF1 PF05970.14 KNZ79697.1 - 4.1e-16 59.1 0.2 6.2e-16 58.5 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.14 KNZ79697.1 - 3.2e-06 25.4 0.0 3.6e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 Helicase 4HPAD_g_N PF18671.1 KNZ79697.1 - 0.0035 17.0 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UvrD_C_2 PF13538.6 KNZ79697.1 - 0.0079 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ79698.1 - 3.1e-24 85.8 0.0 3.5e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase PIF1 PF05970.14 KNZ79699.1 - 1.2e-20 74.0 0.1 1.3e-20 73.9 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase MFS_1 PF07690.16 KNZ79700.1 - 3.2e-28 98.7 60.7 1.3e-18 67.0 38.6 4.1 2 2 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ79700.1 - 2.7e-08 33.1 4.0 2.7e-08 33.1 4.0 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter CclA_1 PF16942.5 KNZ79700.1 - 0.33 11.2 6.0 0.45 10.8 2.9 2.7 1 1 2 3 3 3 0 Putative cyclic bacteriocin DUF3522 PF12036.8 KNZ79700.1 - 0.44 10.8 8.3 0.11 12.7 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) DnaJ_C PF01556.18 KNZ79701.1 - 1.4e-36 125.8 0.0 1.8e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KNZ79701.1 - 3.7e-23 81.4 1.4 6.1e-23 80.7 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KNZ79701.1 - 4.3e-09 36.6 17.1 4.3e-09 36.6 17.1 1.9 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 KNZ79701.1 - 0.13 12.3 16.2 0.13 12.2 1.7 2.9 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 KNZ79701.1 - 1.5 8.9 10.1 0.043 13.8 3.3 1.9 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 KNZ79701.1 - 1.8 9.1 6.2 6.3 7.3 6.3 1.9 1 1 0 1 1 1 0 Cytochrome c3 SET PF00856.28 KNZ79702.1 - 1.5e-07 32.0 0.0 9.6e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 KNZ79703.1 - 2.1e-56 191.2 0.1 2.4e-55 187.8 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79703.1 - 2.3e-17 63.1 0.4 2.9e-08 33.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ79703.1 - 2.8e-07 30.7 0.0 2.1e-05 24.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ79703.1 - 0.0045 15.8 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KNZ79703.1 - 0.039 13.3 0.3 0.076 12.4 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KNZ79703.1 - 0.067 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.8 KNZ79703.1 - 0.14 12.2 0.0 0.43 10.6 0.0 1.7 2 0 0 2 2 2 0 Aconitate B N-terminal domain Glyco_hydro_18 PF00704.28 KNZ79704.1 - 1.2e-21 77.8 0.7 3.6e-21 76.2 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 KNZ79704.1 - 0.018 15.6 0.5 0.018 15.6 0.5 3.7 3 0 0 3 3 3 0 Carbohydrate binding domain CBM_5_12_2 PF14600.6 KNZ79704.1 - 0.34 10.9 18.5 0.36 10.8 7.5 3.2 3 1 0 3 3 3 0 Cellulose-binding domain Glyco_hydro_18 PF00704.28 KNZ79705.1 - 1e-21 78.0 0.2 7.1e-21 75.2 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 RAP1 PF07218.11 KNZ79705.1 - 0.62 8.3 1.8 1 7.6 1.8 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DNA_pol_A_exo1 PF01612.20 KNZ79706.1 - 1.7e-14 53.9 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Spc7_N PF15402.6 KNZ79707.1 - 0.043 12.1 10.4 0.053 11.8 10.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Translin PF01997.16 KNZ79710.1 - 1.2e-73 247.5 0.1 1.4e-73 247.3 0.1 1.1 1 0 0 1 1 1 1 Translin family BLM10_mid PF16507.5 KNZ79712.1 - 9.1e-144 480.0 0.2 2.1e-139 465.6 0.0 4.0 2 1 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KNZ79712.1 - 1.8e-29 101.5 0.1 1.8e-28 98.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 KNZ79712.1 - 6.2e-08 32.3 5.4 0.0082 16.3 0.1 7.1 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KNZ79712.1 - 3.1e-05 24.3 1.2 0.3 11.5 0.0 5.1 6 0 0 6 6 6 1 HEAT repeats Arm PF00514.23 KNZ79712.1 - 0.0042 17.1 0.5 0.11 12.6 0.0 3.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HD_assoc PF13286.6 KNZ79712.1 - 0.014 15.9 0.0 0.063 13.8 0.0 2.2 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Vac14_Fab1_bd PF12755.7 KNZ79712.1 - 0.034 14.7 0.6 31 5.2 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.14 KNZ79712.1 - 0.053 12.8 0.9 0.17 11.1 0.2 2.2 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 KNZ79712.1 - 7.7 7.1 7.2 1.1e+02 3.5 0.1 5.5 5 1 1 6 6 6 0 HEAT-like repeat DUF2630 PF10944.8 KNZ79713.1 - 0.16 12.5 4.2 0.24 11.9 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) zf-RVT PF13966.6 KNZ79714.1 - 0.002 18.8 0.5 0.002 18.8 0.5 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase EXS PF03124.14 KNZ79715.1 - 8.1e-82 275.2 32.6 1.1e-81 274.8 32.6 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KNZ79715.1 - 2.8e-41 142.7 0.4 6.3e-32 111.9 0.0 2.3 2 0 0 2 2 2 2 SPX domain DUF4118 PF13493.6 KNZ79715.1 - 0.18 11.6 4.3 0.49 10.2 4.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) MAF_flag10 PF01973.18 KNZ79716.1 - 0.055 13.2 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF115 Mitofilin PF09731.9 KNZ79718.1 - 5.5e-20 71.8 10.2 5.9e-20 71.7 10.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF3135 PF11333.8 KNZ79718.1 - 1.5 9.2 5.7 13 6.2 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) CDC73_C PF05179.14 KNZ79719.1 - 1.3e-50 171.1 0.7 2.2e-50 170.4 0.7 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 KNZ79719.1 - 1e-08 34.9 0.2 0.00067 19.1 0.0 2.3 2 0 0 2 2 2 2 Paf1 complex subunit CDC73 N-terminal tRNA_int_end_N2 PF12928.7 KNZ79720.1 - 4e-21 75.0 0.0 6.7e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KNZ79720.1 - 0.0028 17.3 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain HTH_33 PF13592.6 KNZ79720.1 - 0.048 13.3 0.1 1.2 8.8 0.4 2.4 1 1 1 2 2 2 0 Winged helix-turn helix ubiquitin PF00240.23 KNZ79722.1 - 5.7e-13 48.4 0.0 1.2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 KNZ79722.1 - 8.6e-08 32.6 4.5 8.6e-08 32.6 4.5 1.7 1 1 1 2 2 2 1 Blt1 N-terminal domain Rad60-SLD PF11976.8 KNZ79722.1 - 8.9e-05 22.3 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like fn3 PF00041.21 KNZ79722.1 - 0.087 13.2 0.6 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III domain Ndufs5 PF10200.9 KNZ79723.1 - 0.0015 18.7 0.1 0.002 18.3 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 KNZ79723.1 - 0.0028 17.7 1.1 0.0085 16.2 1.2 1.8 1 1 1 2 2 2 1 CHCH domain Cmc1 PF08583.10 KNZ79723.1 - 0.0044 17.0 0.3 0.0065 16.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like PADR1 PF08063.12 KNZ79723.1 - 0.095 12.5 1.5 5 7.0 0.5 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain UPF0086 PF01868.16 KNZ79724.1 - 4.8e-30 103.3 0.0 1.7e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Phage_Coat_A PF05357.13 KNZ79724.1 - 0.053 13.3 0.2 0.84 9.5 0.1 2.6 2 1 0 2 2 2 0 Phage Coat Protein A Rgp1 PF08737.10 KNZ79724.1 - 0.097 11.8 0.3 1.3 8.1 0.2 2.0 2 0 0 2 2 2 0 Rgp1 Cpn60_TCP1 PF00118.24 KNZ79725.1 - 1.2e-143 479.4 14.1 1.3e-143 479.2 14.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 KNZ79725.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Cytochrom_C PF00034.21 KNZ79726.1 - 5e-11 43.6 0.0 6.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KNZ79726.1 - 3.1e-08 33.8 2.4 2.3e-07 31.0 2.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KNZ79726.1 - 0.00028 20.6 0.2 0.0027 17.4 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain SMC_N PF02463.19 KNZ79727.1 - 1.2e-43 149.1 0.0 2.5e-43 148.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KNZ79727.1 - 1.5e-26 93.0 0.1 7.3e-26 90.8 0.1 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KNZ79727.1 - 6.7e-05 22.8 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 KNZ79727.1 - 0.0045 17.2 0.0 0.016 15.4 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF1192 PF06698.11 KNZ79727.1 - 0.49 10.5 0.0 0.49 10.5 0.0 8.6 7 3 2 9 9 9 0 Protein of unknown function (DUF1192) DUF2939 PF11159.8 KNZ79727.1 - 1.1 9.7 6.9 24 5.4 0.4 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Pox_A_type_inc PF04508.12 KNZ79727.1 - 5.3 7.1 10.3 0.87 9.6 0.6 3.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 KNZ79727.1 - 6.4 5.5 101.0 0.13 11.1 16.7 5.6 2 2 2 5 5 5 0 Spc7 kinetochore protein Polysacc_deac_1 PF01522.21 KNZ79727.1 - 8.6 6.3 6.6 28 4.6 0.0 3.8 4 0 0 4 4 4 0 Polysaccharide deacetylase SQS_PSY PF00494.19 KNZ79728.1 - 1.9e-36 126.0 0.0 2.4e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase VQ PF05678.14 KNZ79728.1 - 0.2 11.2 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 VQ motif Bromo_TP PF07524.13 KNZ79729.1 - 8.4e-07 28.9 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 KNZ79729.1 - 0.04 14.3 0.1 0.071 13.5 0.1 1.3 1 0 0 1 1 1 0 CENP-S protein SRAP PF02586.14 KNZ79730.1 - 6.7e-61 205.6 0.0 9.6e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) GET2 PF08690.10 KNZ79730.1 - 3.3 7.3 6.7 6.2 6.4 6.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 IMPDH PF00478.25 KNZ79731.1 - 1.3e-132 442.0 0.0 2e-132 441.4 0.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KNZ79731.1 - 9e-14 51.7 0.6 7.8e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 KNZ79731.1 - 9.5e-10 38.0 2.2 3.3e-09 36.2 2.4 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 KNZ79731.1 - 3.8e-08 33.1 4.9 9.1e-07 28.6 3.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.14 KNZ79731.1 - 0.00019 20.8 1.0 0.00036 19.9 1.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KNZ79731.1 - 0.00022 20.8 3.1 0.0013 18.2 1.1 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein UcrQ PF02939.16 KNZ79732.1 - 1.8e-15 56.6 0.0 2e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 UcrQ family DASH_Dam1 PF08653.10 KNZ79733.1 - 2.8e-21 75.1 1.8 6.3e-21 73.9 1.8 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 Syntaxin PF00804.25 KNZ79733.1 - 0.0032 17.2 2.8 0.0041 16.8 2.8 1.2 1 0 0 1 1 1 1 Syntaxin DUF4519 PF15012.6 KNZ79733.1 - 0.21 11.8 1.0 0.43 10.8 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) CUE PF02845.16 KNZ79734.1 - 5.5e-05 22.8 0.0 8.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain Pkinase PF00069.25 KNZ79735.1 - 3.1e-80 269.3 0.0 2.2e-47 161.7 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79735.1 - 2.5e-69 233.4 0.0 1.5e-32 112.9 0.0 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79735.1 - 2.5e-08 33.6 0.0 4e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KNZ79735.1 - 0.0074 16.2 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ79735.1 - 0.092 11.5 0.0 0.25 10.1 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 KNZ79736.1 - 4.4e-09 36.1 0.0 4.1e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79736.1 - 0.018 14.3 0.0 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase tRNA-synt_2 PF00152.20 KNZ79738.1 - 6.7e-75 252.1 0.0 9.1e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNZ79738.1 - 1.2e-12 47.6 0.0 9e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KNZ79738.1 - 3.5e-08 33.3 0.0 0.00044 19.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) eIF-5a PF01287.20 KNZ79739.1 - 1.1e-28 99.2 0.5 1.5e-28 98.7 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KNZ79739.1 - 0.062 13.3 0.1 0.097 12.7 0.1 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain LIM PF00412.22 KNZ79740.1 - 2.2e-11 43.8 6.1 2.2e-11 43.8 6.1 1.5 2 0 0 2 2 2 1 LIM domain zf_UBZ PF18439.1 KNZ79740.1 - 0.031 13.9 2.0 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 KNZ79740.1 - 0.13 12.4 1.3 8.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-Mss51 PF13824.6 KNZ79740.1 - 0.23 11.6 2.3 1.6 8.9 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Auto_anti-p27 PF06677.12 KNZ79740.1 - 0.31 11.2 3.3 2.3 8.4 1.1 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 KNZ79740.1 - 0.44 10.7 6.7 6.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 KNZ79740.1 - 0.52 10.6 4.6 18 5.7 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon DZR PF12773.7 KNZ79740.1 - 1.8 8.6 6.6 7.1 6.7 6.6 2.0 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 KNZ79740.1 - 2 8.8 4.9 4.2 7.8 4.9 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar PIH1 PF08190.12 KNZ79741.1 - 3e-19 69.1 0.0 4.5e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain DAHP_synth_1 PF00793.20 KNZ79742.1 - 2.6e-74 249.5 0.0 1.3e-57 194.7 0.0 2.0 2 0 0 2 2 2 2 DAHP synthetase I family APC1_C PF18122.1 KNZ79743.1 - 3.2e-35 121.5 0.4 7.4e-35 120.4 0.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 KNZ79743.1 - 4e-06 27.4 0.0 1.9e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 KNZ79743.1 - 0.017 15.5 4.9 8.4 7.0 0.0 4.5 4 0 0 4 4 4 0 Proteasome/cyclosome repeat zf-RanBP PF00641.18 KNZ79744.1 - 0.00052 19.3 18.0 0.0012 18.1 4.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AAA_12 PF13087.6 KNZ79745.1 - 5.9e-57 192.5 0.0 1e-56 191.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ79745.1 - 7.6e-49 166.8 0.2 1.3e-48 166.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ79745.1 - 5e-12 46.4 0.2 3.8e-11 43.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ79745.1 - 1.6e-09 37.8 0.0 3.5e-06 26.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KNZ79745.1 - 5.6e-06 26.1 0.5 1.1e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KNZ79745.1 - 0.00094 19.0 0.1 6 6.5 0.0 3.9 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KNZ79745.1 - 0.011 16.1 0.1 0.38 11.2 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HSBP1 PF06825.12 KNZ79745.1 - 0.019 14.8 0.7 0.15 11.9 0.6 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 XhlA PF10779.9 KNZ79745.1 - 0.022 15.0 0.7 0.022 15.0 0.7 1.8 2 0 0 2 2 1 0 Haemolysin XhlA Nup54 PF13874.6 KNZ79745.1 - 0.045 13.9 1.7 0.11 12.6 1.7 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 AAA_7 PF12775.7 KNZ79745.1 - 0.048 13.2 0.7 7.5 6.0 0.1 2.3 1 1 1 2 2 2 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 KNZ79745.1 - 0.058 13.4 1.1 3.5 7.6 0.0 2.9 3 0 0 3 3 3 0 Flavivirus DEAD domain PhoH PF02562.16 KNZ79745.1 - 0.068 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_6 PF12774.7 KNZ79745.1 - 0.069 12.1 0.1 0.16 10.9 0.0 1.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region IMPDH PF00478.25 KNZ79745.1 - 0.1 11.6 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain AAA_22 PF13401.6 KNZ79745.1 - 0.15 12.3 0.1 0.6 10.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KNZ79745.1 - 0.21 10.8 1.3 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SLX9 PF15341.6 KNZ79745.1 - 1.6 9.2 4.8 0.76 10.2 1.2 2.2 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 AAA_12 PF13087.6 KNZ79746.1 - 9.4e-28 97.2 0.0 2.3e-27 95.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KNZ79746.1 - 6.6e-21 75.3 4.4 6.2e-13 49.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KNZ79746.1 - 5.4e-08 33.3 0.0 1.6e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ79746.1 - 5.4e-07 29.5 0.0 5.7e-05 22.9 0.0 2.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ79746.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 KNZ79746.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KNZ79746.1 - 0.018 15.4 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 KNZ79746.1 - 0.2 10.8 0.0 4 6.5 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase MFS_1 PF07690.16 KNZ79747.1 - 3.8e-11 42.5 0.2 4.6e-11 42.2 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ79747.1 - 0.0072 15.2 0.1 0.0084 15.0 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 KNZ79748.1 - 3.8e-67 226.6 0.0 4.3e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Syja_N PF02383.18 KNZ79750.1 - 3e-76 256.8 0.0 4.3e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain WD40 PF00400.32 KNZ79751.1 - 2.2e-59 196.0 35.4 4.1e-09 36.9 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79751.1 - 4.7e-23 81.3 1.7 0.0022 18.3 0.0 5.4 3 3 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 KNZ79751.1 - 5.8e-08 33.1 0.0 9.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 KNZ79751.1 - 5.6e-07 28.6 2.9 0.09 11.4 0.1 4.4 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ79751.1 - 0.0002 20.4 0.0 0.59 9.0 0.0 4.1 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KNZ79751.1 - 0.0026 16.6 0.7 2.9 6.5 0.0 3.8 3 1 0 4 4 4 1 Nup133 N terminal like PD40 PF07676.12 KNZ79751.1 - 0.02 14.8 0.2 4.2 7.4 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 KNZ79751.1 - 0.087 10.8 0.1 0.14 10.1 0.1 1.2 1 0 0 1 1 1 0 IKI3 family PQQ_3 PF13570.6 KNZ79751.1 - 0.13 12.8 1.2 9.1 6.9 0.2 3.7 2 1 1 3 3 3 0 PQQ-like domain WD40_like PF17005.5 KNZ79751.1 - 0.26 10.6 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain FAD_binding_1 PF00667.20 KNZ79752.1 - 3.1e-35 121.7 0.0 5e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 KNZ79752.1 - 3.5e-26 92.1 0.0 7e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KNZ79752.1 - 2.7e-11 44.1 0.0 7.1e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain IBR PF01485.21 KNZ79754.1 - 8.5e-06 25.9 6.6 8.5e-06 25.9 6.6 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain RSN1_7TM PF02714.15 KNZ79754.1 - 0.21 10.9 1.3 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Ald_Xan_dh_C2 PF02738.18 KNZ79755.1 - 3.6e-174 580.2 0.6 2e-90 303.8 0.1 2.1 1 1 1 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KNZ79755.1 - 3.5e-39 134.3 0.0 6.9e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 KNZ79755.1 - 6.4e-33 113.4 1.3 1.5e-32 112.2 1.3 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 KNZ79755.1 - 2.4e-30 104.8 0.2 1e-29 102.7 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 KNZ79755.1 - 7.1e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain MOSC_N PF03476.16 KNZ79756.1 - 1.5e-17 63.5 0.0 4e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 KNZ79756.1 - 4.6e-14 52.2 0.0 1.4e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V zf-C2H2_4 PF13894.6 KNZ79757.1 - 4.9e-05 23.8 14.9 0.0055 17.4 2.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ79757.1 - 0.00011 22.5 17.3 0.0047 17.3 2.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 KNZ79757.1 - 0.0045 16.7 1.3 0.0045 16.7 1.3 2.2 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-BED PF02892.15 KNZ79757.1 - 0.0063 16.5 7.2 0.45 10.6 0.4 2.6 1 1 1 2 2 2 2 BED zinc finger zf-H2C2_2 PF13465.6 KNZ79757.1 - 0.0091 16.4 12.6 0.33 11.5 0.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain Zn-ribbon_8 PF09723.10 KNZ79757.1 - 0.15 12.2 0.7 0.41 10.8 0.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-Di19 PF05605.12 KNZ79757.1 - 0.29 11.5 3.0 2 8.8 0.1 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AA_permease_2 PF13520.6 KNZ79759.1 - 1.8e-44 152.3 53.7 2.2e-44 152.0 53.7 1.0 1 0 0 1 1 1 1 Amino acid permease zf-RVT PF13966.6 KNZ79760.1 - 0.00055 20.6 1.0 0.00077 20.1 1.0 1.3 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase DUF5472 PF17566.2 KNZ79760.1 - 0.24 11.4 1.1 0.53 10.3 1.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5472) Rft-1 PF04506.13 KNZ79763.1 - 1.6e-63 215.3 2.1 2.3e-63 214.7 2.1 1.1 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 KNZ79763.1 - 0.0099 15.3 3.9 0.01 15.3 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein SAP PF02037.27 KNZ79763.1 - 0.053 13.3 0.7 0.096 12.5 0.7 1.5 1 0 0 1 1 1 0 SAP domain VIT1 PF01988.19 KNZ79763.1 - 0.18 11.6 1.1 0.44 10.4 1.1 1.6 1 0 0 1 1 1 0 VIT family PPR_2 PF13041.6 KNZ79764.1 - 5.1e-08 33.0 0.0 0.029 14.6 0.0 5.1 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KNZ79764.1 - 5.3e-07 29.6 0.0 1.5 8.9 0.0 5.5 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.20 KNZ79764.1 - 3e-06 27.1 5.2 12 6.4 0.0 8.1 8 1 0 8 8 8 2 PPR repeat PPR_long PF17177.4 KNZ79764.1 - 3.7e-06 26.5 0.0 0.3 10.4 0.0 3.4 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP ERAP1_C PF11838.8 KNZ79764.1 - 6.7e-05 22.6 0.1 0.00027 20.6 0.0 2.0 3 0 0 3 3 3 1 ERAP1-like C-terminal domain TPR_14 PF13428.6 KNZ79764.1 - 0.31 12.0 6.1 6.2 7.9 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat CBFD_NFYB_HMF PF00808.23 KNZ79765.1 - 1.1e-20 73.6 0.9 1.5e-20 73.2 0.9 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ79765.1 - 5.7e-12 46.1 0.8 6.2e-12 46.0 0.1 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KNZ79765.1 - 0.0084 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.17 KNZ79765.1 - 0.12 12.5 0.3 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) TAFII28 PF04719.14 KNZ79765.1 - 0.16 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Ish1 PF10281.9 KNZ79766.1 - 1e-62 208.1 25.3 4.9e-11 42.7 0.5 7.6 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 KNZ79766.1 - 3.2e-06 26.8 10.6 0.089 12.5 0.0 6.9 7 1 0 7 7 7 1 HeH/LEM domain ADSL_C PF10397.9 KNZ79766.1 - 0.00034 21.1 0.8 0.97 10.0 0.0 3.5 4 0 0 4 4 4 2 Adenylosuccinate lyase C-terminus SAP PF02037.27 KNZ79766.1 - 0.001 18.7 0.0 31 4.5 0.0 5.2 5 0 0 5 5 5 0 SAP domain Slx4 PF09494.10 KNZ79766.1 - 0.0017 18.3 0.0 16 5.5 0.0 4.4 3 1 0 3 3 3 1 Slx4 endonuclease LEM PF03020.15 KNZ79766.1 - 0.0074 15.8 0.0 10 5.8 0.0 4.8 6 0 0 6 6 6 1 LEM domain NDUF_C2 PF06374.11 KNZ79766.1 - 0.033 14.3 0.2 66 3.7 0.0 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) SAM_2 PF07647.17 KNZ79766.1 - 4.6 7.4 9.2 12 6.1 0.2 4.4 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) Aldo_ket_red PF00248.21 KNZ79767.1 - 6.3e-40 137.2 0.2 1.1e-37 129.9 0.2 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family CLP1_P PF16575.5 KNZ79768.1 - 2.3e-34 118.8 0.0 5.3e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 KNZ79768.1 - 0.0038 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KNZ79768.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CobU PF02283.16 KNZ79768.1 - 0.053 13.1 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase FtsK_SpoIIIE PF01580.18 KNZ79768.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 KNZ79768.1 - 0.1 13.0 0.0 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase WGG PF10273.9 KNZ79769.1 - 5.8e-26 91.0 0.2 5.8e-26 91.0 0.2 1.8 2 1 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 KNZ79769.1 - 0.039 14.1 0.4 0.081 13.1 0.1 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF1840 PF08895.11 KNZ79769.1 - 0.073 13.4 0.8 0.12 12.7 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) TIP49 PF06068.13 KNZ79770.1 - 2.4e-158 526.9 0.1 2.9e-158 526.6 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KNZ79770.1 - 3.3e-18 65.6 0.0 7.2e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KNZ79770.1 - 4.2e-10 40.1 0.1 2.1e-06 28.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNZ79770.1 - 2.2e-08 34.0 0.0 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KNZ79770.1 - 1.3e-06 28.8 0.1 0.026 14.8 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KNZ79770.1 - 1.4e-05 25.2 0.1 0.0057 16.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ79770.1 - 2.1e-05 25.0 0.0 0.00015 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KNZ79770.1 - 0.00049 20.4 0.0 0.0036 17.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KNZ79770.1 - 0.0012 18.4 0.1 0.0024 17.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ79770.1 - 0.0017 18.7 0.7 0.013 15.9 0.7 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 KNZ79770.1 - 0.034 13.8 0.0 4.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 KNZ79770.1 - 0.037 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 KNZ79770.1 - 0.039 13.3 0.1 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KNZ79770.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KNZ79770.1 - 0.05 13.1 0.1 0.42 10.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KNZ79770.1 - 0.054 14.0 0.1 0.37 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KNZ79770.1 - 0.064 13.3 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 KNZ79770.1 - 0.075 12.3 0.3 0.26 10.5 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 KNZ79770.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ysc84 PF04366.12 KNZ79772.1 - 7.4e-37 126.0 0.4 1.2e-36 125.3 0.4 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KNZ79772.1 - 4.4e-17 61.4 0.1 9.4e-17 60.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ79772.1 - 4.5e-12 45.6 0.0 1.3e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 KNZ79772.1 - 4.8e-11 42.2 0.0 2.6e-09 36.6 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 KNZ79772.1 - 0.16 11.7 0.1 0.44 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) rve PF00665.26 KNZ79774.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain POT1PC PF16686.5 KNZ79774.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.5 2 0 0 2 2 2 0 ssDNA-binding domain of telomere protection protein HEAT PF02985.22 KNZ79775.1 - 5.7e-17 60.4 4.7 4.9e-05 23.2 0.0 6.8 6 0 0 6 6 6 3 HEAT repeat Importin_rep_4 PF18808.1 KNZ79775.1 - 4.2e-16 59.0 0.0 1.5e-15 57.3 0.0 2.0 1 0 0 1 1 1 1 Importin repeat HEAT_EZ PF13513.6 KNZ79775.1 - 2.1e-15 56.8 13.6 1.4e-07 31.9 0.0 6.8 6 1 1 7 7 7 4 HEAT-like repeat HEAT_2 PF13646.6 KNZ79775.1 - 1.8e-11 44.3 6.5 4e-05 23.9 0.0 6.0 4 2 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KNZ79775.1 - 2.5e-09 37.6 0.0 0.00033 21.2 0.0 3.4 1 1 2 3 3 3 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KNZ79775.1 - 2.2e-05 24.5 0.0 0.00088 19.4 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 KNZ79775.1 - 5.2e-05 23.2 0.0 0.77 9.7 0.0 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF3385) DUF4042 PF13251.6 KNZ79775.1 - 0.005 16.6 2.9 6.9 6.3 0.0 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF4042) Adaptin_N PF01602.20 KNZ79775.1 - 0.0058 15.2 0.0 0.015 13.9 0.0 1.6 1 0 0 1 1 1 1 Adaptin N terminal region Cnd3 PF12719.7 KNZ79775.1 - 0.1 11.8 1.1 1.6 7.8 0.0 3.1 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Acetyltransf_1 PF00583.25 KNZ79777.1 - 2.5e-14 53.5 0.1 2.9e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ79777.1 - 1.4e-09 37.9 0.2 1.6e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ79777.1 - 1.3e-07 31.9 0.1 1.8e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ79777.1 - 3.3e-06 27.0 0.3 9.8e-06 25.5 0.2 1.7 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_15 PF17013.5 KNZ79777.1 - 0.00012 21.6 0.9 0.0002 20.9 0.4 1.6 1 1 0 2 2 2 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 KNZ79777.1 - 0.043 13.9 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAD_M PF08527.10 KNZ79777.1 - 0.14 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain adh_short PF00106.25 KNZ79778.1 - 2.4e-16 59.8 0.3 4.4e-12 45.9 0.0 3.2 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ79778.1 - 1.3e-11 44.5 0.0 2.5e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pox_F15 PF04596.12 KNZ79779.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus protein F15 G-alpha PF00503.20 KNZ79780.1 - 1.5e-118 396.1 0.9 1.7e-118 395.9 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ79780.1 - 5.4e-17 61.8 0.9 4.3e-12 45.8 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ79780.1 - 1e-05 25.0 1.9 0.0003 20.2 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 KNZ79780.1 - 0.0027 17.9 1.2 1.2 9.3 0.1 2.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KNZ79780.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KNZ79780.1 - 0.058 13.5 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase zf-CHC2 PF01807.20 KNZ79780.1 - 0.078 12.8 0.0 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.18 KNZ79780.1 - 0.12 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Helitron_like_N PF14214.6 KNZ79781.1 - 3.1e-26 92.8 0.0 3.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ79781.1 - 0.049 13.6 0.0 0.058 13.3 0.0 1.1 1 0 0 1 1 1 0 Inovirus Gp2 PIF1 PF05970.14 KNZ79783.1 - 6.3e-110 367.8 0.0 7.3e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ79783.1 - 9.1e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ79783.1 - 0.0048 17.3 0.0 0.0083 16.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain 4HPAD_g_N PF18671.1 KNZ79783.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal ResIII PF04851.15 KNZ79783.1 - 0.016 15.2 0.0 0.051 13.6 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KNZ79783.1 - 0.069 12.9 0.2 0.14 11.9 0.2 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.8 KNZ79783.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Herpes_Helicase PF02689.14 KNZ79784.1 - 5.4e-07 28.0 0.0 5.6e-07 27.9 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ79784.1 - 0.00099 18.9 0.1 0.0029 17.4 0.1 1.8 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF1192 PF06698.11 KNZ79788.1 - 0.89 9.7 4.6 0.21 11.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HSP90 PF00183.18 KNZ79789.1 - 1.2e-129 433.6 1.8 1.2e-129 433.6 1.8 3.3 3 1 0 3 3 3 1 Hsp90 protein FF PF01846.19 KNZ79789.1 - 6e-30 103.2 14.5 6.1e-10 39.1 0.0 6.4 6 0 0 6 6 6 4 FF domain WW PF00397.26 KNZ79789.1 - 4.4e-10 39.5 3.5 2.6e-08 33.8 0.4 2.6 2 0 0 2 2 2 2 WW domain HATPase_c_3 PF13589.6 KNZ79789.1 - 7.1e-09 35.6 0.0 2.4e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KNZ79789.1 - 2.5e-06 28.0 0.0 6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5347 PF17282.2 KNZ79789.1 - 0.05 13.9 0.9 1.7 9.0 0.2 3.7 3 1 1 4 4 4 0 Family of unknown function (DUF5347) RhoGAP-FF1 PF16512.5 KNZ79789.1 - 0.18 12.5 10.1 0.37 11.5 2.3 3.9 2 1 1 3 3 3 0 p190-A and -B Rho GAPs FF domain Kelch_4 PF13418.6 KNZ79791.1 - 4.4e-18 65.0 5.9 0.013 15.5 0.1 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KNZ79791.1 - 4.7e-11 42.7 14.3 0.0053 17.0 1.3 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ79791.1 - 2.5e-10 40.3 1.5 0.12 12.7 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 KNZ79791.1 - 7.3e-09 35.1 1.1 0.021 14.4 0.0 5.1 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 KNZ79791.1 - 0.0024 17.8 7.6 1.7 8.7 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Cytochrom_B561 PF03188.16 KNZ79791.1 - 0.0088 16.2 1.1 0.0088 16.2 1.1 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Pox_A14 PF05767.12 KNZ79791.1 - 0.055 13.6 0.0 0.18 12.0 0.0 1.9 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Kelch_2 PF07646.15 KNZ79791.1 - 0.064 13.3 3.0 22 5.2 0.1 4.5 5 0 0 5 5 5 0 Kelch motif DUF4131 PF13567.6 KNZ79791.1 - 4.2 7.0 12.4 0.4 10.3 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MgtE PF01769.16 KNZ79791.1 - 8.9 6.7 10.5 1.8 8.9 0.9 2.3 2 0 0 2 2 2 0 Divalent cation transporter Cid2 PF09774.9 KNZ79793.1 - 8.5e-26 91.3 8.3 7.4e-25 88.2 8.3 1.9 1 1 0 1 1 1 1 Caffeine-induced death protein 2 KicB PF03882.14 KNZ79793.1 - 0.062 13.5 0.5 0.12 12.6 0.1 1.6 2 0 0 2 2 2 0 MukF winged-helix domain GILT PF03227.16 KNZ79794.1 - 3.7e-15 56.1 0.2 5.8e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Yos1 PF08571.10 KNZ79795.1 - 8e-28 96.5 1.7 1.3e-27 95.8 1.7 1.3 1 1 0 1 1 1 1 Yos1-like Ribosomal_L22 PF00237.19 KNZ79796.1 - 8.9e-22 77.3 0.1 1.4e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribophorin_I PF04597.14 KNZ79797.1 - 3.9e-133 444.9 1.1 4.4e-133 444.7 1.1 1.0 1 0 0 1 1 1 1 Ribophorin I PPR_2 PF13041.6 KNZ79799.1 - 1.3e-17 63.7 0.9 1.5e-11 44.3 0.0 4.8 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 KNZ79799.1 - 3.7e-07 30.0 2.1 0.034 14.4 0.0 5.0 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 KNZ79799.1 - 0.013 15.6 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Asp PF00026.23 KNZ79800.1 - 9.7e-28 97.5 0.1 1.7e-26 93.4 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ79800.1 - 0.00061 20.1 2.6 0.25 11.6 0.1 3.2 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ79800.1 - 0.014 16.0 0.0 5.7 7.7 0.0 2.9 2 0 0 2 2 2 0 Aspartyl protease EphA2_TM PF14575.6 KNZ79800.1 - 0.024 15.5 0.0 0.22 12.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PepSY_TM PF03929.16 KNZ79800.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region Stevor PF17410.2 KNZ79800.1 - 0.1 12.1 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SIT PF15330.6 KNZ79800.1 - 0.19 12.2 0.0 3.7 8.0 0.0 2.3 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4381 PF14316.6 KNZ79800.1 - 0.23 11.7 0.1 0.46 10.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Prominin PF05478.11 KNZ79800.1 - 0.32 8.9 0.0 0.43 8.5 0.0 1.1 1 0 0 1 1 1 0 Prominin Fe-ADH PF00465.19 KNZ79801.1 - 3e-92 309.3 0.0 3.8e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KNZ79801.1 - 2.6e-13 50.3 0.0 1e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase His_biosynth PF00977.21 KNZ79802.1 - 4.7e-29 101.5 0.0 6.1e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_L29 PF00831.23 KNZ79803.1 - 1.1e-19 70.1 2.8 1.1e-19 70.1 2.8 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 KNZ79803.1 - 0.014 15.5 2.4 0.016 15.3 1.0 1.8 2 1 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Taeniidae_ag PF05596.11 KNZ79803.1 - 0.045 13.7 3.6 0.3 11.1 0.7 2.5 2 0 0 2 2 2 0 Taeniidae antigen Snapin_Pallidin PF14712.6 KNZ79803.1 - 0.12 12.8 9.2 1.1 9.7 1.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin XhlA PF10779.9 KNZ79803.1 - 0.41 10.9 3.9 2.2 8.5 0.2 2.7 2 1 1 3 3 3 0 Haemolysin XhlA Pkinase PF00069.25 KNZ79804.1 - 1.7e-72 244.0 0.0 2.5e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79804.1 - 7.2e-48 163.1 0.0 1.3e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ79804.1 - 0.00013 20.9 0.2 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KNZ79804.1 - 0.00021 20.7 0.0 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KNZ79804.1 - 0.017 14.5 0.0 0.21 10.9 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ79804.1 - 0.018 14.0 0.1 0.16 10.9 0.1 2.1 1 1 0 1 1 1 0 Haspin like kinase domain DUF4384 PF14326.6 KNZ79804.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) Polysacc_deac_1 PF01522.21 KNZ79805.1 - 2.1e-27 95.5 0.0 4.2e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase TFIIF_alpha PF05793.12 KNZ79806.1 - 4.5e-09 35.4 51.3 2.1e-05 23.3 42.2 4.1 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HLH PF00010.26 KNZ79806.1 - 0.035 14.1 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain MAS20 PF02064.15 KNZ79806.1 - 4.8 7.3 6.0 3.5 7.7 0.0 2.8 2 0 0 2 2 2 0 MAS20 protein import receptor AAA PF00004.29 KNZ79807.1 - 0.0001 22.7 0.0 0.00063 20.2 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ79807.1 - 0.0052 17.2 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 KNZ79807.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 KNZ79807.1 - 0.025 13.8 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain NTPase_1 PF03266.15 KNZ79807.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 KNZ79807.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 KNZ79807.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cupin_8 PF13621.6 KNZ79808.1 - 4.5e-60 203.5 0.0 6.5e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KNZ79808.1 - 0.00059 19.4 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 KNZ79808.1 - 0.0032 17.2 0.9 0.04 13.6 0.1 2.4 3 0 0 3 3 3 1 Cupin domain JmjC PF02373.22 KNZ79808.1 - 0.0069 16.8 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Ribosomal_L7Ae PF01248.26 KNZ79809.1 - 1.2e-23 82.6 1.6 1.2e-23 82.6 1.6 1.9 3 0 0 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ABC_tran_CTD PF16326.5 KNZ79810.1 - 0.00066 19.9 1.9 0.00066 19.9 1.9 6.1 4 2 1 5 5 4 2 ABC transporter C-terminal domain DUF5082 PF16888.5 KNZ79810.1 - 0.019 15.3 21.1 3.7 7.8 2.5 5.4 3 1 2 5 5 5 0 Domain of unknown function (DUF5082) Occludin_ELL PF07303.13 KNZ79810.1 - 0.023 15.4 13.8 0.65 10.7 0.9 4.4 2 1 1 3 3 3 0 Occludin homology domain AlphaC_C PF17480.2 KNZ79810.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.9 3 0 0 3 3 3 0 AlphaC C-terminal DUF4094 PF13334.6 KNZ79810.1 - 0.23 11.9 4.4 10 6.6 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Sec34 PF04136.15 KNZ79810.1 - 0.48 10.3 4.7 1 9.3 0.9 2.5 2 0 0 2 2 2 0 Sec34-like family UPF0184 PF03670.13 KNZ79810.1 - 0.62 10.5 5.8 8.4 6.9 2.0 3.8 2 2 0 3 3 3 0 Uncharacterised protein family (UPF0184) Tup_N PF08581.10 KNZ79810.1 - 0.72 10.2 12.7 2.4 8.5 1.0 4.2 2 1 2 4 4 4 0 Tup N-terminal Baculo_PEP_C PF04513.12 KNZ79810.1 - 1 9.4 4.9 4.4 7.3 0.2 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KNZ79810.1 - 1.6 9.0 4.2 42 4.5 0.1 3.6 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) FlgM PF04316.13 KNZ79810.1 - 3.4 8.1 15.3 0.13 12.6 0.6 4.1 2 1 1 3 3 3 0 Anti-sigma-28 factor, FlgM CALCOCO1 PF07888.11 KNZ79810.1 - 4.6 6.0 29.7 4.5 6.0 1.2 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like STN1_2 PF09170.10 KNZ79810.1 - 5.6 7.1 8.4 0.86 9.8 1.3 2.3 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 RFX_DNA_binding PF02257.15 KNZ79811.1 - 1.7e-27 95.8 0.0 5.1e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain NuDC PF16273.5 KNZ79811.1 - 0.02 15.4 5.7 0.042 14.4 5.7 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain DMA PF03474.14 KNZ79813.1 - 0.055 13.1 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 DMRTA motif AMP-binding PF00501.28 KNZ79814.1 - 8.9e-43 146.4 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KNZ79814.1 - 2.1e-09 37.1 1.1 4.1e-09 36.2 1.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus MARVEL PF01284.23 KNZ79815.1 - 0.055 13.5 15.7 2.1 8.4 16.7 2.2 1 1 1 2 2 2 0 Membrane-associating domain DUF2079 PF09852.9 KNZ79815.1 - 0.062 12.1 6.5 0.083 11.7 6.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Ac76 PF05814.11 KNZ79815.1 - 0.15 12.1 2.6 1.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Orf76 (Ac76) PepSY_TM_like_2 PF16357.5 KNZ79815.1 - 0.16 11.9 6.6 2.7 7.9 2.2 2.3 2 0 0 2 2 2 0 Putative PepSY_TM-like 7TMR-DISM_7TM PF07695.11 KNZ79815.1 - 0.57 10.1 15.1 1.9 8.3 15.1 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF4383 PF14325.6 KNZ79815.1 - 1.5 9.1 12.2 13 6.1 6.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) DUF2569 PF10754.9 KNZ79815.1 - 7.5 7.0 11.5 0.78 10.2 2.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF3810 PF12725.7 KNZ79815.1 - 9.6 5.4 9.3 1.4 8.2 2.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) PUNUT PF16913.5 KNZ79816.1 - 0.31 10.2 3.9 0.51 9.5 0.3 1.9 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport DUF4203 PF13886.6 KNZ79817.1 - 0.00015 21.5 1.6 0.0002 21.1 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) HupE_UreJ_2 PF13795.6 KNZ79817.1 - 0.003 17.2 1.9 0.0038 16.9 1.9 1.1 1 0 0 1 1 1 1 HupE / UreJ protein GPI2 PF06432.11 KNZ79817.1 - 0.031 13.7 2.0 0.037 13.5 2.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase MtrC PF04211.13 KNZ79817.1 - 0.051 12.6 0.3 0.067 12.2 0.3 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C UQ_con PF00179.26 KNZ79818.1 - 1.1e-38 132.0 0.2 1.4e-38 131.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Uteroglobin PF01099.17 KNZ79818.1 - 0.027 14.8 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 Uteroglobin family UEV PF05743.13 KNZ79818.1 - 0.078 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 UEV domain FmiP_Thoc5 PF09766.9 KNZ79819.1 - 1.7e-36 126.3 15.8 1.8e-36 126.2 15.8 1.0 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 FAM178 PF14816.6 KNZ79819.1 - 0.0023 17.0 1.6 0.0023 17.0 1.6 1.7 1 1 1 2 2 2 1 Family of unknown function, FAM178 FATC PF02260.20 KNZ79819.1 - 0.015 15.1 0.5 0.035 13.9 0.1 1.8 2 0 0 2 2 2 0 FATC domain DUF3258 PF11646.8 KNZ79819.1 - 0.091 12.9 0.2 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF3258 TssO PF17561.2 KNZ79819.1 - 0.28 11.3 4.3 0.12 12.5 1.4 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO FAM76 PF16046.5 KNZ79819.1 - 0.69 9.2 6.7 0.88 8.9 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein G6PD_C PF02781.16 KNZ79820.1 - 1.1e-94 316.9 0.0 6.4e-91 304.5 0.0 2.4 2 1 1 3 3 3 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KNZ79820.1 - 4.2e-58 196.9 0.0 6.1e-58 196.4 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF1682 PF07946.14 KNZ79823.1 - 1.1e-91 307.5 1.1 1.2e-91 307.3 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Afi1 PF07792.12 KNZ79823.1 - 0.1 13.0 1.0 0.18 12.3 1.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 KNZ79823.1 - 4.6 6.9 6.2 7.4 6.2 6.2 1.2 1 0 0 1 1 1 0 FAM176 family LON_substr_bdg PF02190.16 KNZ79825.1 - 7.5e-26 91.3 0.0 1.1e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KNZ79825.1 - 6.8e-11 41.8 26.5 2.7e-09 36.7 12.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ79825.1 - 5.8e-08 32.5 22.5 1.1e-05 25.2 11.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNZ79825.1 - 1.4e-07 31.5 19.8 0.00013 22.0 1.9 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KNZ79825.1 - 3.3e-07 30.1 5.7 3.3e-07 30.1 5.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ79825.1 - 2.9e-06 27.2 23.8 0.0035 17.3 10.6 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 KNZ79825.1 - 5.2e-06 26.7 11.2 5.2e-06 26.7 11.2 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KNZ79825.1 - 3e-05 23.9 24.5 0.0015 18.4 11.4 2.5 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 KNZ79825.1 - 0.00087 19.1 8.2 0.00087 19.1 8.2 3.4 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KNZ79825.1 - 0.0096 16.0 3.3 0.0096 16.0 3.3 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 KNZ79825.1 - 0.099 12.5 3.6 6.7 6.6 0.4 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-P11 PF03854.14 KNZ79825.1 - 4.6 7.0 11.7 0.34 10.6 5.3 2.3 2 0 0 2 2 2 0 P-11 zinc finger UQ_con PF00179.26 KNZ79827.1 - 3e-20 72.3 0.0 5.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.21 KNZ79827.1 - 3e-05 24.2 3.6 9e-05 22.6 3.6 1.8 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain APC1_C PF18122.1 KNZ79827.1 - 0.049 13.6 0.0 0.71 9.8 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain DZR PF12773.7 KNZ79827.1 - 0.054 13.5 3.7 0.2 11.7 3.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon ACBP PF00887.19 KNZ79827.1 - 0.075 13.3 0.0 2.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Acyl CoA binding protein DUF1184 PF06683.11 KNZ79827.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) Mito_carr PF00153.27 KNZ79828.1 - 5.3e-49 164.1 5.9 1.9e-16 59.8 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.6 KNZ79828.1 - 0.052 13.7 0.0 5.1 7.3 0.1 2.5 2 0 0 2 2 2 0 PrcB C-terminal RTP1_C1 PF10363.9 KNZ79829.1 - 2e-35 121.4 0.0 2.7e-34 117.7 0.0 2.9 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KNZ79829.1 - 0.017 14.8 0.1 0.017 14.8 0.1 2.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Urb2 PF10441.9 KNZ79829.1 - 0.055 13.4 4.1 0.17 11.8 1.4 2.9 2 1 0 2 2 2 0 Urb2/Npa2 family HEAT_EZ PF13513.6 KNZ79829.1 - 0.11 13.0 7.1 1.3 9.6 0.0 5.0 5 1 1 6 6 6 0 HEAT-like repeat Tab2_like PF06485.11 KNZ79829.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Sedlin_N PF04628.13 KNZ79830.1 - 9e-20 71.1 0.2 1.3e-19 70.7 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region GTP_EFTU PF00009.27 KNZ79831.1 - 4e-46 157.0 0.0 5.3e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KNZ79831.1 - 4.5e-32 110.7 0.7 1.1e-14 54.7 0.1 3.3 2 1 1 3 3 3 2 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KNZ79831.1 - 8.7e-09 35.6 0.1 2.6e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ79831.1 - 0.0018 18.4 0.1 0.012 15.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ79831.1 - 0.0053 16.7 0.1 3.2 7.6 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase PAM2 PF07145.15 KNZ79831.1 - 0.03 14.0 0.7 0.096 12.4 0.1 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Ndc1_Nup PF09531.10 KNZ79831.1 - 0.37 9.4 4.4 0.49 9.0 4.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 KNZ79831.1 - 2.4 7.2 8.2 3.5 6.7 8.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SH3_9 PF14604.6 KNZ79832.1 - 2.2e-39 133.1 5.2 2.3e-13 49.8 0.1 3.8 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 KNZ79832.1 - 4.7e-35 118.9 8.3 9.8e-15 53.9 0.1 3.9 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 KNZ79832.1 - 2.5e-30 104.1 0.0 4.8e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 KNZ79832.1 - 8.3e-22 76.6 0.3 1.3e-06 27.9 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_10 PF17902.1 KNZ79832.1 - 1.9e-05 24.6 0.5 0.041 14.0 0.0 3.7 4 0 0 4 4 4 2 SH3 domain SH3_3 PF08239.11 KNZ79832.1 - 0.00044 20.5 1.6 0.4 11.0 0.1 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain hSH3 PF14603.6 KNZ79832.1 - 0.00077 19.8 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 Helically-extended SH3 domain SAM_4 PF18017.1 KNZ79832.1 - 0.0083 16.1 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Usp PF00582.26 KNZ79832.1 - 0.35 11.4 5.3 1.1 9.8 5.3 1.8 1 0 0 1 1 1 0 Universal stress protein family GARP PF16731.5 KNZ79832.1 - 9.7 5.8 22.0 18 5.0 22.0 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma Sec7 PF01369.20 KNZ79833.1 - 4.5e-72 241.6 0.3 9.6e-72 240.5 0.3 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KNZ79833.1 - 7.7e-46 155.9 2.2 7.7e-46 155.9 2.2 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KNZ79833.1 - 1.7e-33 114.3 0.3 1.7e-33 114.3 0.3 5.5 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 KNZ79833.1 - 4.8e-23 81.7 1.5 2.4e-19 69.7 0.1 3.9 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 HEAT PF02985.22 KNZ79833.1 - 0.0011 19.1 0.6 1.3 9.4 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat DUF1539 PF07560.11 KNZ79833.1 - 0.077 13.1 0.0 8.1 6.5 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Cas_APE2256 PF09651.10 KNZ79833.1 - 0.17 11.7 0.0 0.57 10.1 0.0 1.9 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) DS PF01916.17 KNZ79834.1 - 2.2e-126 421.0 0.0 2.7e-126 420.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase 14-3-3 PF00244.20 KNZ79835.1 - 1.7e-35 122.6 0.0 1.9e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 14-3-3 protein zf-CCHC PF00098.23 KNZ79836.1 - 1.3e-30 104.0 49.5 2.2e-06 27.5 3.2 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 KNZ79836.1 - 1.4e-11 44.0 24.1 0.004 16.8 1.2 5.4 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 KNZ79836.1 - 3.7e-05 23.5 32.4 0.00092 19.0 1.5 5.6 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.6 KNZ79836.1 - 0.0025 17.5 24.4 0.027 14.2 1.0 5.3 3 2 2 5 5 5 3 GAG-polyprotein viral zinc-finger Mu-like_Com PF10122.9 KNZ79836.1 - 0.14 11.6 16.6 0.33 10.4 0.3 4.3 3 1 1 4 4 4 0 Mu-like prophage protein Com zf-CCHC_3 PF13917.6 KNZ79836.1 - 0.44 10.5 33.5 1.2 9.1 1.4 6.0 3 1 2 5 5 5 0 Zinc knuckle Rad50_zn_hook PF04423.14 KNZ79836.1 - 1.3 8.9 0.0 1.3 8.9 0.0 4.1 5 0 0 5 5 5 0 Rad50 zinc hook motif DZR PF12773.7 KNZ79836.1 - 6.1 7.0 32.6 67 3.6 4.6 4.5 2 2 1 3 3 3 0 Double zinc ribbon Polyketide_cyc PF03364.20 KNZ79837.1 - 5.2e-23 81.7 0.0 6.7e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GST_N_3 PF13417.6 KNZ79838.1 - 3.7e-08 33.7 0.1 7.7e-08 32.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ79838.1 - 0.012 15.6 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ79838.1 - 0.043 14.0 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GTP_EFTU_D2 PF03144.25 KNZ79838.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 2 GST_N_2 PF13409.6 KNZ79838.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF150_C PF17384.2 KNZ79838.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Chitin_synth_1 PF01644.17 KNZ79839.1 - 2.6e-66 222.6 0.0 4.1e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KNZ79839.1 - 3.5e-29 100.6 0.1 8.7e-29 99.3 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KNZ79839.1 - 7.7e-24 84.2 0.3 2e-18 66.3 0.0 2.4 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KNZ79839.1 - 1.4e-08 34.9 0.3 5e-08 33.1 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 RNA_pol_Rpb4 PF03874.16 KNZ79840.1 - 2e-19 70.1 0.1 3.4e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.21 KNZ79840.1 - 0.066 13.5 0.3 0.3 11.4 0.0 2.1 3 0 0 3 3 3 0 Death effector domain Spo12 PF05032.12 KNZ79841.1 - 2e-14 53.2 0.5 2e-14 53.2 0.5 1.8 2 0 0 2 2 2 1 Spo12 family Sel1 PF08238.12 KNZ79842.1 - 9.9e-17 61.0 12.5 0.00046 20.8 0.0 6.4 6 1 1 7 7 7 4 Sel1 repeat TPR_2 PF07719.17 KNZ79842.1 - 0.021 14.9 0.8 0.14 12.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ79842.1 - 0.12 12.2 0.3 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SAE2 PF08573.10 KNZ79842.1 - 8.7 7.5 7.2 21 6.3 2.7 2.4 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Ras PF00071.22 KNZ79843.1 - 4.5e-46 156.4 0.2 5.2e-46 156.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ79843.1 - 3e-14 53.3 0.0 4.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ79843.1 - 2.9e-06 26.9 0.0 3.5e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ79843.1 - 0.00036 20.1 0.2 0.00076 19.1 0.1 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KNZ79843.1 - 0.00041 20.4 0.1 0.0015 18.6 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KNZ79843.1 - 0.0018 17.7 0.0 0.0024 17.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 KNZ79843.1 - 0.0019 18.1 0.3 0.018 14.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 KNZ79843.1 - 0.031 13.8 0.1 0.092 12.3 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 KNZ79843.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mannosidase_ig PF17786.1 KNZ79844.1 - 5.4e-16 59.0 0.1 2e-15 57.1 0.1 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KNZ79844.1 - 7e-08 33.1 0.0 4e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KNZ79844.1 - 1.6e-05 24.6 0.0 4.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain DUF1508 PF07411.12 KNZ79844.1 - 0.016 15.0 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1508) Glyco_hydro_2_N PF02837.18 KNZ79844.1 - 0.034 14.0 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain MFS_1 PF07690.16 KNZ79845.1 - 1e-35 123.3 32.6 1.2e-35 123.1 32.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4079 PF13301.6 KNZ79845.1 - 3.2 7.9 8.3 0.62 10.2 2.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) zf-RING_2 PF13639.6 KNZ79846.1 - 2.7e-06 27.6 7.9 5.7e-06 26.6 7.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KNZ79846.1 - 1.6e-05 24.9 1.5 2.6e-05 24.2 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KNZ79846.1 - 6.5e-05 23.1 5.7 0.00011 22.4 5.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KNZ79846.1 - 8.7e-05 22.3 4.5 0.00016 21.4 4.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ79846.1 - 0.00067 19.5 3.3 0.019 14.8 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ79846.1 - 0.00078 19.4 6.5 0.0017 18.3 6.5 1.5 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KNZ79846.1 - 0.00091 19.0 8.2 0.0021 17.9 2.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KNZ79846.1 - 0.001 19.0 4.4 0.001 19.0 4.4 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNZ79846.1 - 0.0017 18.1 9.4 0.002 18.0 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KNZ79846.1 - 0.026 14.3 5.5 0.15 11.9 5.7 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 KNZ79846.1 - 0.034 13.9 2.8 0.054 13.3 2.0 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KNZ79846.1 - 0.16 12.2 5.1 0.24 11.6 1.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING tRNA-synt_2c PF01411.19 KNZ79847.1 - 1.8e-06 26.8 0.0 2.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KNZ79847.1 - 0.0015 18.5 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain MFS_1 PF07690.16 KNZ79848.1 - 1.2e-31 109.9 39.5 1.2e-31 109.9 39.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily NIF PF03031.18 KNZ79849.1 - 1.9e-50 170.7 0.0 2.7e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Snf7 PF03357.21 KNZ79850.1 - 1.2e-34 119.4 17.5 1.2e-34 119.4 17.5 1.5 2 0 0 2 2 2 1 Snf7 Indigoidine_A PF04227.12 KNZ79850.1 - 0.03 13.7 4.2 0.05 13.0 0.2 2.1 1 1 1 2 2 2 0 Indigoidine synthase A like protein MecA_N PF05223.11 KNZ79850.1 - 1.2 9.4 6.2 0.7 10.2 0.2 2.2 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Atg14 PF10186.9 KNZ79850.1 - 8.4 5.4 14.5 14 4.7 14.5 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Endonuc_Holl PF10107.9 KNZ79850.1 - 9.9 6.0 8.0 2.9 7.7 4.4 1.8 1 1 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase TRAM_LAG1_CLN8 PF03798.16 KNZ79851.1 - 2.2e-43 148.3 19.4 2.5e-43 148.1 19.4 1.0 1 0 0 1 1 1 1 TLC domain RRM_1 PF00076.22 KNZ79852.1 - 1.3e-17 63.3 0.1 8e-08 32.0 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ79852.1 - 0.00018 21.3 0.1 0.0038 17.0 0.0 2.4 2 1 0 2 2 2 1 Occluded RNA-recognition motif Tim54 PF11711.8 KNZ79852.1 - 0.011 14.5 0.7 0.015 14.1 0.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTCRA PF15028.6 KNZ79852.1 - 0.02 14.6 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DAP PF15228.6 KNZ79852.1 - 0.16 13.1 0.5 0.34 12.1 0.5 1.5 1 0 0 1 1 1 0 Death-associated protein DJ-1_PfpI PF01965.24 KNZ79853.1 - 8.8e-17 61.4 0.0 2.6e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KNZ79853.1 - 2.7e-05 24.0 0.0 0.00042 20.1 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like BRCT PF00533.26 KNZ79853.1 - 0.047 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Mob1_phocein PF03637.17 KNZ79854.1 - 2.4e-77 258.7 0.0 2.8e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.29 KNZ79856.1 - 2e-36 125.4 0.0 3.2e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ79856.1 - 2.1e-24 86.0 0.0 4.6e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KNZ79856.1 - 0.018 15.3 0.1 0.086 13.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF302 PF03625.14 KNZ79857.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF302 Dynamin_N PF00350.23 KNZ79859.1 - 3.5e-19 69.5 0.1 3.5e-19 69.5 0.1 4.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 KNZ79859.1 - 9.3e-06 25.7 0.3 0.0079 16.3 0.1 3.0 1 1 1 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ79859.1 - 0.0037 17.2 0.2 0.027 14.4 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 KNZ79859.1 - 0.0051 16.2 0.0 0.022 14.1 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_tran PF00005.27 KNZ79859.1 - 0.033 14.7 0.1 0.033 14.7 0.1 2.7 3 1 0 3 3 3 0 ABC transporter AAA_16 PF13191.6 KNZ79859.1 - 0.04 14.3 0.2 0.29 11.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 KNZ79859.1 - 0.052 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DLP_helical PF18709.1 KNZ79859.1 - 2.3 7.3 15.3 0.097 11.9 3.2 3.2 3 0 0 3 3 3 0 Dynamin-like helical domain PilJ PF13675.6 KNZ79859.1 - 3.2 7.8 5.3 6.9 6.7 0.0 3.7 4 1 1 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term Tup_N PF08581.10 KNZ79859.1 - 7.9 6.9 9.1 0.68 10.3 0.8 2.8 2 0 0 2 2 2 0 Tup N-terminal XhlA PF10779.9 KNZ79859.1 - 8.3 6.7 14.1 19 5.5 1.1 2.8 2 0 0 2 2 2 0 Haemolysin XhlA ATP_bind_1 PF03029.17 KNZ79861.1 - 2.4e-76 256.7 0.0 3.2e-76 256.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 KNZ79861.1 - 0.0004 20.8 0.0 0.0031 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 KNZ79861.1 - 0.0096 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ArsA_ATPase PF02374.15 KNZ79861.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_7 PF12775.7 KNZ79861.1 - 0.011 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 KNZ79861.1 - 0.012 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 KNZ79861.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KNZ79861.1 - 0.017 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF463 PF04317.12 KNZ79861.1 - 0.019 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_29 PF13555.6 KNZ79861.1 - 0.032 14.0 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CbiA PF01656.23 KNZ79861.1 - 0.041 13.9 0.0 0.058 13.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KNZ79861.1 - 0.042 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 KNZ79861.1 - 0.044 13.3 0.0 1.9 8.0 0.0 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 KNZ79861.1 - 0.051 13.5 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KNZ79861.1 - 0.088 12.7 0.1 0.52 10.2 0.0 2.1 3 0 0 3 3 2 0 NTPase AAA_14 PF13173.6 KNZ79861.1 - 0.1 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ79861.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KNZ79861.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KNZ79861.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 KNZ79861.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 KNZ79861.1 - 0.16 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 KNZ79861.1 - 0.17 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Ploopntkinase3 PF18751.1 KNZ79861.1 - 0.2 11.5 0.0 20 5.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF2075 PF09848.9 KNZ79861.1 - 0.25 10.5 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KNZ79861.1 - 0.26 10.2 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mago-bind PF09282.10 KNZ79862.1 - 1.2e-14 53.9 2.8 2e-14 53.1 2.8 1.4 1 0 0 1 1 1 1 Mago binding Pox_Ag35 PF03286.14 KNZ79862.1 - 0.0033 17.2 8.4 0.0038 17.0 8.4 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CPSF100_C PF13299.6 KNZ79862.1 - 0.11 12.7 4.1 0.15 12.2 4.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1640 PF07798.11 KNZ79863.1 - 1.7e-35 122.7 8.4 1.8e-35 122.5 8.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1195 PF06708.11 KNZ79863.1 - 0.036 13.8 1.4 0.051 13.3 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1195) DUF1664 PF07889.12 KNZ79863.1 - 0.38 10.8 6.3 0.91 9.6 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GST_N PF02798.20 KNZ79864.1 - 1.4e-12 47.7 0.0 3.2e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KNZ79864.1 - 6.5e-12 45.7 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ79864.1 - 8.6e-12 45.1 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KNZ79864.1 - 1.3e-08 35.1 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KNZ79864.1 - 2.9e-08 33.8 0.0 8e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNZ79864.1 - 9.1e-06 25.6 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ79865.1 - 3.7e-13 49.5 0.0 6.3e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KNZ79865.1 - 1.9e-11 44.1 0.0 3.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KNZ79865.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ79865.1 - 3.6e-08 33.3 0.1 8.7e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KNZ79865.1 - 3.9e-07 30.3 0.0 1.3e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KNZ79865.1 - 5.2e-07 29.8 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF5054 PF16477.5 KNZ79865.1 - 0.064 13.0 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5054) GCV_T PF01571.21 KNZ79866.1 - 0.0094 15.3 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain ACPS PF01648.20 KNZ79867.1 - 2e-17 63.4 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 KNZ79867.1 - 0.06 13.5 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain WD40 PF00400.32 KNZ79868.1 - 1.6e-36 123.7 23.2 8.1e-05 23.3 0.0 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79868.1 - 7.4e-09 35.8 1.0 3.8 7.9 0.1 6.9 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ79868.1 - 0.0099 14.9 0.0 4.6 6.1 0.0 3.9 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DEAD PF00270.29 KNZ79869.1 - 7.1e-18 65.0 0.0 1.3e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ79869.1 - 1.8e-09 37.9 0.0 4.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.22 KNZ79870.1 - 1.8e-09 37.3 0.0 1.4e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ79870.1 - 0.0088 15.9 0.0 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Complex1_LYR_2 PF13233.6 KNZ79871.1 - 6.1e-15 55.7 0.1 7.7e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Sua5_yciO_yrdC PF01300.18 KNZ79872.1 - 7.3e-51 172.2 0.0 1.2e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KNZ79872.1 - 3.2e-27 95.7 0.0 4.8e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding HMG_box PF00505.19 KNZ79873.1 - 5.3e-13 49.2 0.1 8.6e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box MFS_1 PF07690.16 KNZ79874.1 - 2.5e-30 105.6 19.5 3.6e-30 105.1 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nucleo_P87 PF07267.11 KNZ79874.1 - 3.1 6.6 9.6 5.6 5.7 9.6 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Thiolase_N PF00108.23 KNZ79875.1 - 1.5e-41 142.5 0.1 2.1e-41 142.0 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNZ79875.1 - 1.6e-39 134.3 0.4 2.4e-39 133.8 0.4 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Dodecin PF07311.12 KNZ79875.1 - 0.094 13.0 0.6 0.21 11.9 0.1 1.9 2 0 0 2 2 2 0 Dodecin Autophagy_act_C PF03987.15 KNZ79876.1 - 1.1e-16 61.2 1.7 1.5e-16 60.7 1.7 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.18 KNZ79877.1 - 1.5e-94 315.2 2.7 1.8e-94 315.0 2.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 KNZ79877.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region LMP PF04778.12 KNZ79877.1 - 0.04 13.8 0.2 0.074 13.0 0.2 1.5 1 0 0 1 1 1 0 LMP repeated region TipAS PF07739.13 KNZ79877.1 - 0.15 12.6 0.2 1.5 9.4 0.0 2.3 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Pribosyltran PF00156.27 KNZ79878.1 - 4.2e-14 52.4 0.0 5.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KNZ79878.1 - 0.0036 16.8 0.0 0.005 16.3 0.0 1.4 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.20 KNZ79879.1 - 2.3e-99 333.4 0.0 3.2e-99 332.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 KNZ79879.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 PA domain TMEM117 PF15113.6 KNZ79879.1 - 0.078 11.9 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 TMEM117 protein family Auto_anti-p27 PF06677.12 KNZ79880.1 - 1.9e-25 88.7 5.0 1.6e-12 47.3 0.5 2.3 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Tlr3_TMD PF17968.1 KNZ79882.1 - 6.7 7.0 8.3 34 4.7 3.0 2.9 1 1 1 2 2 2 0 Toll-like receptor 3 trans-membrane domain Ribonuclease_3 PF00636.26 KNZ79884.1 - 4e-39 133.5 0.0 2e-19 70.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KNZ79884.1 - 2e-21 76.5 0.0 8.1e-10 38.9 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KNZ79884.1 - 4e-07 30.1 0.0 2.4e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Dicer dimerisation domain PAZ PF02170.22 KNZ79884.1 - 6.4e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 PAZ domain COX7C PF02935.16 KNZ79885.1 - 1.6e-18 66.7 4.8 2.7e-18 66.0 4.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.22 KNZ79886.1 - 7.2e-177 588.5 0.1 8.1e-177 588.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_4 PF13562.6 KNZ79886.1 - 0.18 12.0 0.1 0.31 11.2 0.1 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Proteasome PF00227.26 KNZ79887.1 - 3.7e-60 202.7 0.0 5.4e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KNZ79887.1 - 2e-07 30.6 0.2 5.9e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature AhpC-TSA PF00578.21 KNZ79888.1 - 1.2e-32 112.5 0.0 1.3e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNZ79888.1 - 5.4e-14 52.1 0.0 5.8e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KNZ79888.1 - 0.051 13.7 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ssu72 PF04722.13 KNZ79889.1 - 3.1e-76 255.2 0.0 3.4e-76 255.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Syntaxin-18_N PF10496.9 KNZ79890.1 - 8.2e-14 51.6 0.2 8.2e-14 51.6 0.2 2.6 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 KNZ79890.1 - 0.069 13.2 2.9 0.38 10.8 0.0 3.0 3 0 0 3 3 3 0 SNARE domain DUF2877 PF11392.8 KNZ79890.1 - 0.43 11.3 2.5 0.39 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) CENP-H PF05837.12 KNZ79890.1 - 4.7 7.7 16.8 2.7 8.4 5.6 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SNARE_assoc PF09335.11 KNZ79891.1 - 3.4e-15 56.6 5.7 3.4e-15 56.6 5.7 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF2530 PF10745.9 KNZ79891.1 - 0.13 12.5 1.2 0.53 10.5 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) DUF2304 PF10066.9 KNZ79891.1 - 7.1 6.9 14.3 0.2 11.9 4.6 3.1 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2304) Cys_Met_Meta_PP PF01053.20 KNZ79893.1 - 5.5e-56 189.7 0.0 1.3e-55 188.5 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.18 KNZ79894.1 - 1.2e-18 67.1 0.0 2.5e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ79894.1 - 7.1e-05 22.8 6.9 0.00013 22.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.18 KNZ79895.1 - 3e-07 30.6 0.0 5.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Lytic transglycolase SASRP1 PF15160.6 KNZ79895.1 - 0.0067 16.1 0.0 2.4 7.8 0.0 2.1 2 0 0 2 2 2 2 Spermatogenesis-associated serine-rich protein 1 WD40 PF00400.32 KNZ79896.1 - 2.1e-49 164.4 30.7 1.3e-08 35.3 0.3 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79896.1 - 2.5e-23 82.2 4.9 0.00017 21.8 0.0 9.3 5 4 4 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KNZ79896.1 - 1.8e-20 73.2 1.6 1.8e-20 73.2 1.6 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40_like PF17005.5 KNZ79896.1 - 1.5e-09 37.6 0.2 0.062 12.6 0.0 4.9 4 1 1 5 5 5 3 WD40-like domain Nup160 PF11715.8 KNZ79896.1 - 8.5e-09 34.6 10.3 0.0047 15.6 0.1 5.8 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ79896.1 - 2.8e-06 26.6 4.5 0.13 11.2 0.3 5.6 3 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 KNZ79896.1 - 0.0015 17.9 0.0 0.055 12.7 0.0 2.7 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Utp21 PF04192.12 KNZ79896.1 - 0.0035 16.9 1.6 0.082 12.4 0.1 2.3 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain Nucleoporin_N PF08801.11 KNZ79896.1 - 0.012 14.3 8.3 0.52 9.0 0.1 5.1 3 2 3 6 6 6 0 Nup133 N terminal like eIF2A PF08662.11 KNZ79896.1 - 0.014 15.3 1.4 11 5.8 0.0 4.4 2 1 3 5 5 5 0 Eukaryotic translation initiation factor eIF2A BBS2_N PF14781.6 KNZ79896.1 - 0.014 15.3 0.2 11 6.0 0.0 3.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal BBS2_Mid PF14783.6 KNZ79896.1 - 0.096 12.7 7.4 9.2 6.3 0.0 5.9 6 1 0 7 7 7 0 Ciliary BBSome complex subunit 2, middle region Peptidase_M18 PF02127.15 KNZ79897.1 - 5.1e-148 493.4 0.0 5.8e-148 493.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 KNZ79897.1 - 0.00026 20.1 0.1 0.015 14.3 0.1 2.4 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase Brix PF04427.18 KNZ79898.1 - 3e-28 99.3 0.7 4.6e-28 98.6 0.7 1.3 1 0 0 1 1 1 1 Brix domain ATE_C PF04377.15 KNZ79899.1 - 4.5e-47 160.0 0.3 7.5e-47 159.3 0.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KNZ79899.1 - 1.6e-27 95.7 4.9 3.4e-27 94.6 4.9 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DASH_Dad4 PF08650.10 KNZ79900.1 - 2.8e-25 88.1 3.3 3.2e-25 87.9 3.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 Tektin PF03148.14 KNZ79900.1 - 0.0038 16.0 1.6 0.004 16.0 1.6 1.0 1 0 0 1 1 1 1 Tektin family WD40 PF00400.32 KNZ79901.1 - 0.00026 21.7 0.3 0.6 11.1 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1513 PF07433.11 KNZ79901.1 - 0.011 14.9 0.0 0.027 13.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) ANAPC4_WD40 PF12894.7 KNZ79901.1 - 0.023 15.0 0.0 0.73 10.2 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 KNZ79903.1 - 2.5e-25 88.7 3.9 2.5e-16 59.9 0.1 3.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KNZ79903.1 - 3.5e-25 85.6 9.0 4.8e-08 32.0 0.1 4.9 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.6 KNZ79903.1 - 2.8e-21 73.6 6.0 1.9e-06 27.4 0.1 5.4 5 1 1 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 KNZ79903.1 - 8.3e-14 50.4 9.5 0.00023 20.5 0.2 5.2 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 KNZ79903.1 - 1.4e-13 50.4 5.8 0.00014 21.6 0.4 4.2 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 KNZ79903.1 - 1.2e-08 34.9 1.0 0.018 15.0 0.1 3.9 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KNZ79903.1 - 0.0017 18.6 1.6 0.038 14.3 0.3 3.1 3 2 2 5 5 5 1 EF-hand domain SPARC_Ca_bdg PF10591.9 KNZ79903.1 - 0.0017 18.6 0.8 0.49 10.7 0.1 3.3 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 KNZ79903.1 - 0.014 15.5 0.0 1.3 9.2 0.0 2.9 3 0 0 3 3 3 0 EF hand SUIM_assoc PF16619.5 KNZ79903.1 - 0.19 11.8 0.5 0.36 10.9 0.5 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Caleosin PF05042.13 KNZ79903.1 - 0.23 11.4 4.2 17 5.3 0.1 3.3 3 1 1 4 4 4 0 Caleosin related protein EMC3_TMCO1 PF01956.16 KNZ79904.1 - 1.1e-40 139.2 0.0 1.5e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like V-SNARE PF05008.15 KNZ79905.1 - 4.1e-23 81.5 6.8 1.6e-22 79.7 1.6 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 KNZ79905.1 - 3.1e-16 59.4 12.4 4.6e-16 58.9 6.6 3.2 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KNZ79905.1 - 0.0009 19.1 0.8 0.0009 19.1 0.8 2.2 2 1 0 2 2 2 1 Sec20 YqjK PF13997.6 KNZ79905.1 - 0.0038 17.4 0.1 0.014 15.6 0.1 2.1 1 0 0 1 1 1 1 YqjK-like protein DUF1664 PF07889.12 KNZ79905.1 - 0.009 16.0 4.3 0.85 9.7 0.3 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) DUF883 PF05957.13 KNZ79905.1 - 0.012 16.3 5.1 1.4 9.5 1.4 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 KNZ79905.1 - 0.022 14.3 11.3 0.26 10.8 11.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Pex24p PF06398.11 KNZ79905.1 - 0.038 13.0 0.1 0.038 13.0 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LMBR1 PF04791.16 KNZ79905.1 - 0.055 12.4 2.1 0.065 12.1 2.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec8_exocyst PF04048.14 KNZ79905.1 - 0.1 12.4 3.3 3 7.7 0.1 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain Laminin_II PF06009.12 KNZ79905.1 - 0.2 11.7 6.5 4.2 7.4 0.4 2.1 2 0 0 2 2 2 0 Laminin Domain II Nbl1_Borealin_N PF10444.9 KNZ79905.1 - 0.25 11.0 3.9 0.25 11.0 0.0 2.9 3 1 1 4 4 4 0 Nbl1 / Borealin N terminal DUF241 PF03087.14 KNZ79905.1 - 6.5 6.5 10.8 1.3 8.8 4.5 2.4 1 1 1 2 2 2 0 Arabidopsis protein of unknown function KCH PF16944.5 KNZ79906.1 - 2.7e-89 299.3 16.9 3.3e-89 299.0 16.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3917 PF13055.6 KNZ79906.1 - 0.073 13.5 0.5 0.073 13.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3917) zf-LITAF-like PF10601.9 KNZ79906.1 - 4 7.8 7.0 0.54 10.6 2.1 2.1 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain MMR_HSR1_Xtn PF16897.5 KNZ79907.1 - 1.9e-39 134.0 1.9 3.7e-39 133.0 0.4 2.2 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KNZ79907.1 - 3.7e-24 84.5 0.0 6.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KNZ79907.1 - 2.6e-20 72.6 0.0 5.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ79907.1 - 3.2e-08 33.3 0.1 7.8e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 KNZ79907.1 - 0.013 14.5 0.8 0.029 13.3 0.2 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 KNZ79907.1 - 0.043 13.9 0.5 13 5.8 0.4 2.3 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 KNZ79907.1 - 0.15 12.0 0.7 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 RsgA GTPase Alg6_Alg8 PF03155.15 KNZ79908.1 - 2.4e-134 448.9 25.3 4.6e-134 448.0 25.3 1.4 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ribonuc_red_sm PF00268.21 KNZ79908.1 - 6.7e-104 347.2 3.1 1e-103 346.6 3.1 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain VMA21 PF09446.10 KNZ79909.1 - 5.5e-12 45.6 6.2 8e-12 45.1 6.2 1.3 1 0 0 1 1 1 1 VMA21-like domain Ribonuc_red_sm PF00268.21 KNZ79910.1 - 2.7e-119 397.8 0.8 3.2e-119 397.5 0.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 KNZ79910.1 - 0.12 13.3 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Aminotran_1_2 PF00155.21 KNZ79911.1 - 2.5e-38 132.2 0.0 2.9e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KNZ79911.1 - 0.0011 17.6 0.0 0.0019 16.8 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Peptidase_S24 PF00717.23 KNZ79912.1 - 9e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KNZ79912.1 - 0.00017 21.4 0.1 0.16 11.7 0.0 3.0 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 DUF1500 PF07389.12 KNZ79912.1 - 0.11 12.6 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1500) Pkinase_Tyr PF07714.17 KNZ79913.1 - 9.9e-43 146.3 0.0 1e-30 106.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ79913.1 - 6.8e-39 133.8 0.0 4.9e-28 98.2 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain APH PF01636.23 KNZ79913.1 - 0.0023 17.9 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ79913.1 - 0.0027 17.0 0.0 0.11 11.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 KNZ79913.1 - 0.0045 16.4 0.1 0.34 10.2 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ebp2 PF05890.12 KNZ79914.1 - 0.0091 15.6 3.0 0.013 15.1 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 TMEM208_SND2 PF05620.11 KNZ79916.1 - 9.2e-29 100.4 1.6 1.4e-28 99.7 1.6 1.2 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Myb_DNA-binding PF00249.31 KNZ79917.1 - 2e-44 149.5 12.8 4.3e-11 42.8 0.2 5.5 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ79917.1 - 2.5e-33 114.1 9.5 4.3e-07 30.1 0.0 5.5 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KNZ79917.1 - 6.7e-08 32.8 12.5 0.046 14.1 0.6 5.6 5 1 0 5 5 5 2 Myb/SANT-like DNA-binding domain NAM-associated PF14303.6 KNZ79917.1 - 0.00078 20.2 0.4 4.5 8.0 4.0 2.6 1 1 1 2 2 2 2 No apical meristem-associated C-terminal domain Myb_DNA-bind_5 PF13873.6 KNZ79917.1 - 0.0036 17.4 3.1 0.15 12.2 0.1 3.5 3 0 0 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 KNZ79917.1 - 0.0047 17.2 5.8 0.026 14.8 0.2 3.7 4 0 0 4 4 4 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KNZ79917.1 - 0.042 14.0 0.0 0.95 9.6 0.0 2.9 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 KNZ79917.1 - 0.086 12.9 0.0 18 5.4 0.0 2.6 2 0 0 2 2 2 0 SLIDE TAF8_C PF10406.9 KNZ79918.1 - 9.9e-11 42.0 3.9 9.9e-11 42.0 3.9 2.9 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KNZ79918.1 - 1.8e-07 31.0 0.1 2.9e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated Flavokinase PF01687.17 KNZ79919.1 - 2.3e-32 111.6 0.0 2.9e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_S11 PF00411.19 KNZ79920.1 - 2.5e-06 27.9 0.0 3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 NPC1_N PF16414.5 KNZ79921.1 - 2.1e-80 269.8 7.3 2.9e-80 269.4 7.3 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KNZ79921.1 - 6.7e-68 229.6 3.9 1.9e-39 135.4 0.0 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 KNZ79921.1 - 7.5e-46 155.8 4.0 7.5e-46 155.8 4.0 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 KNZ79921.1 - 5.4e-05 21.1 5.1 5.4e-05 21.1 5.1 1.7 2 1 1 3 3 3 1 AcrB/AcrD/AcrF family Folate_rec PF03024.14 KNZ79921.1 - 0.00017 21.5 0.8 0.00035 20.5 0.8 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 KNZ79921.1 - 0.0012 17.9 6.7 0.0012 17.9 6.7 2.8 2 1 0 2 2 2 1 MMPL family Diphthamide_syn PF01866.17 KNZ79922.1 - 3.9e-96 322.1 0.0 4.9e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pkinase PF00069.25 KNZ79923.1 - 2e-67 227.3 0.0 2.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79923.1 - 1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KNZ79923.1 - 3.3e-17 62.9 2.0 4.7e-17 62.4 0.3 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 KNZ79923.1 - 2.8e-08 33.4 0.2 2.3e-06 27.1 0.0 2.6 3 0 0 3 3 3 1 Kinase-like C2 PF00168.30 KNZ79923.1 - 1e-07 32.1 0.1 2.8e-05 24.3 0.1 2.4 2 0 0 2 2 2 1 C2 domain Haspin_kinase PF12330.8 KNZ79923.1 - 6.2e-07 28.7 0.1 1.1e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 KNZ79923.1 - 0.00029 20.5 0.1 0.26 10.9 0.1 3.0 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KNZ79923.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79923.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.12 KNZ79924.1 - 1.5e-51 175.1 0.0 1.9e-51 174.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Acyl-CoA_dh_1 PF00441.24 KNZ79926.1 - 1e-24 87.4 0.1 1.9e-24 86.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KNZ79926.1 - 2.8e-17 62.7 0.0 9.2e-17 61.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KNZ79926.1 - 2.1e-11 44.2 0.4 3.8e-11 43.4 0.2 1.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KNZ79926.1 - 0.0057 17.3 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 KNZ79926.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Fungal_trans PF04082.18 KNZ79927.1 - 7.3e-32 110.5 0.0 1.1e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ79927.1 - 5.4e-08 32.8 15.5 1e-07 31.9 15.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 KNZ79928.1 - 5.1e-17 61.5 0.0 1.7e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L19 PF01245.20 KNZ79928.1 - 7e-16 58.1 0.0 1.2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 IMD PF08397.11 KNZ79929.1 - 0.00014 21.3 2.1 0.00014 21.3 2.1 1.5 2 0 0 2 2 2 1 IRSp53/MIM homology domain BAR_3 PF16746.5 KNZ79929.1 - 0.0013 18.5 1.7 0.0023 17.7 1.7 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Arfaptin PF06456.13 KNZ79929.1 - 0.0077 15.8 2.0 0.03 13.9 2.0 1.9 1 1 0 1 1 1 1 Arfaptin-like domain Vac_Fusion PF02346.16 KNZ79929.1 - 0.22 11.1 1.6 0.93 9.2 0.2 2.3 1 1 1 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 HAUS6_N PF14661.6 KNZ79929.1 - 0.93 9.0 4.9 0.48 10.0 2.1 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus tRNA-synt_2 PF00152.20 KNZ79930.1 - 1.2e-86 290.7 0.0 8.9e-86 287.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNZ79930.1 - 3e-06 27.1 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain F-box-like PF12937.7 KNZ79931.1 - 5.2e-06 26.3 0.2 1.3e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ79931.1 - 0.0064 16.4 0.9 0.017 15.0 0.0 2.3 2 1 0 2 2 2 1 F-box domain Exo_endo_phos_2 PF14529.6 KNZ79932.1 - 0.018 14.9 0.7 0.02 14.7 0.1 1.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase RELT PF12606.8 KNZ79935.1 - 0.13 11.2 0.4 0.23 10.5 0.4 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 APH PF01636.23 KNZ79936.1 - 1.5e-06 28.4 0.1 9.3e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ79936.1 - 0.00042 20.0 1.2 0.12 12.0 0.1 2.8 3 0 0 3 3 3 2 RIO1 family Choline_kinase PF01633.20 KNZ79936.1 - 0.0006 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase LRR_4 PF12799.7 KNZ79937.1 - 0.0004 20.7 7.1 0.69 10.4 0.2 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNZ79937.1 - 0.17 12.6 6.2 16 6.5 0.0 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 KNZ79937.1 - 0.99 9.2 5.0 11 5.9 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat ABC_tran PF00005.27 KNZ79938.1 - 3.5e-43 147.4 0.1 1.2e-20 74.4 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KNZ79938.1 - 5.2e-16 59.3 3.2 6.4e-07 29.5 0.6 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNZ79938.1 - 5.4e-12 45.6 1.4 0.0097 15.4 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KNZ79938.1 - 3.7e-08 33.0 0.2 0.0069 16.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 KNZ79938.1 - 1.9e-06 28.5 0.1 0.0071 16.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 KNZ79938.1 - 3.8e-06 27.2 0.1 0.0017 18.5 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 KNZ79938.1 - 1.3e-05 25.5 0.0 0.11 12.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 KNZ79938.1 - 1.4e-05 25.1 0.0 0.25 11.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ79938.1 - 2.9e-05 24.0 0.0 0.1 12.5 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KNZ79938.1 - 3.1e-05 24.6 12.9 0.0071 16.9 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_28 PF13521.6 KNZ79938.1 - 4e-05 23.9 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KNZ79938.1 - 5.5e-05 23.5 0.0 0.25 11.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 KNZ79938.1 - 6.1e-05 22.9 1.1 0.19 11.4 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KNZ79938.1 - 7.6e-05 23.1 0.0 1.8 9.0 0.0 3.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ79938.1 - 0.0001 22.7 0.8 0.071 13.5 0.0 3.4 4 0 0 4 4 2 1 AAA ATPase domain Chromo PF00385.24 KNZ79938.1 - 0.00019 21.2 0.2 0.00048 20.0 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.12 KNZ79938.1 - 0.0002 21.3 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain 4HB PF17947.1 KNZ79938.1 - 0.0003 20.8 0.5 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 Four helical bundle domain HEAT_2 PF13646.6 KNZ79938.1 - 0.00043 20.6 10.6 0.036 14.5 0.4 4.1 3 1 0 3 3 3 1 HEAT repeats AAA_33 PF13671.6 KNZ79938.1 - 0.00053 20.2 0.0 1.7 8.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 KNZ79938.1 - 0.00065 19.7 0.3 3.9 7.3 0.0 3.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea MeaB PF03308.16 KNZ79938.1 - 0.00083 18.4 0.3 0.29 10.1 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KNZ79938.1 - 0.0023 17.7 0.2 4.5 7.0 0.1 3.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 KNZ79938.1 - 0.0032 17.2 0.1 1.7 8.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KNZ79938.1 - 0.0038 16.8 0.3 3.1 7.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_13 PF13166.6 KNZ79938.1 - 0.0071 15.1 0.0 1.5 7.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 KNZ79938.1 - 0.0077 15.9 0.2 11 5.6 0.0 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 KNZ79938.1 - 0.0098 15.1 0.4 2.6 7.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 KNZ79938.1 - 0.01 15.1 0.2 2.9 7.0 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain SbcCD_C PF13558.6 KNZ79938.1 - 0.011 16.0 0.1 1.8 8.8 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 KNZ79938.1 - 0.015 15.5 0.0 9.3 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 KNZ79938.1 - 0.018 14.9 2.6 12 5.7 0.0 3.5 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 KNZ79938.1 - 0.028 14.4 1.9 5.2 7.1 0.1 3.0 3 1 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 KNZ79938.1 - 0.057 13.3 0.1 5.8 6.8 0.0 2.6 2 0 0 2 2 2 0 NTPase U3snoRNP10 PF12397.8 KNZ79938.1 - 0.067 13.5 1.9 0.18 12.2 1.1 2.2 2 1 0 2 2 1 0 U3 small nucleolar RNA-associated protein 10 AAA_14 PF13173.6 KNZ79938.1 - 0.084 12.9 0.1 6.7 6.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 KNZ79938.1 - 0.09 11.9 0.1 4.4 6.4 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_27 PF13514.6 KNZ79938.1 - 0.09 12.4 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KNZ79938.1 - 0.11 12.0 1.7 7.5 6.1 0.1 3.4 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KNZ79938.1 - 0.15 11.4 0.1 2.8 7.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 KNZ79938.1 - 0.15 11.9 0.7 20 5.1 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KNZ79938.1 - 0.47 10.4 4.1 12 6.0 0.1 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) HEAT PF02985.22 KNZ79938.1 - 6.2 7.4 9.9 2.4 8.6 0.2 4.8 5 0 0 5 5 2 0 HEAT repeat V_ATPase_I PF01496.19 KNZ79939.1 - 0 1012.3 0.0 0 1012.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4743 PF15916.5 KNZ79939.1 - 0.063 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4743) APH PF01636.23 KNZ79940.1 - 1.5e-12 48.0 0.1 1.5e-12 47.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ79940.1 - 9.1e-07 28.7 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ79940.1 - 0.027 13.9 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.22 KNZ79940.1 - 0.19 11.3 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 RIO1 family zf-C3HC4 PF00097.25 KNZ79941.1 - 6.2e-09 35.6 11.0 1.3e-08 34.6 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ79941.1 - 7e-09 35.4 11.6 7e-09 35.4 11.6 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ79941.1 - 1.3e-07 31.3 14.1 2.1e-07 30.7 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ79941.1 - 4e-06 27.1 14.0 6.9e-06 26.3 14.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KNZ79941.1 - 2.2e-05 24.7 7.3 4.8e-05 23.6 7.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KNZ79941.1 - 2.7e-05 24.0 14.7 5.5e-05 23.0 13.4 2.1 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KNZ79941.1 - 5.2e-05 23.3 11.1 0.0001 22.3 11.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KNZ79941.1 - 0.00021 21.3 10.2 0.00043 20.2 10.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger TerY_C PF15616.6 KNZ79941.1 - 0.00067 19.8 2.5 0.00089 19.4 2.5 1.3 1 0 0 1 1 1 1 TerY-C metal binding domain Prok-RING_4 PF14447.6 KNZ79941.1 - 0.0012 18.6 12.5 0.0024 17.7 12.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KNZ79941.1 - 0.015 15.4 8.8 0.025 14.7 8.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 KNZ79941.1 - 0.075 13.1 5.0 0.12 12.5 5.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 KNZ79941.1 - 0.094 12.5 5.3 0.18 11.7 5.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit MbtH PF03621.13 KNZ79941.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 MbtH-like protein zf-RING_4 PF14570.6 KNZ79941.1 - 0.16 11.8 12.2 1.5 8.7 12.3 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KNZ79941.1 - 1.5 8.7 8.9 5.4 7.0 8.9 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein CBM_21 PF03370.13 KNZ79942.1 - 1.8e-24 86.1 0.0 2.6e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KNZ79942.1 - 1.4e-08 35.2 0.0 2.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) ChaB PF06150.12 KNZ79942.1 - 0.16 12.5 0.0 0.38 11.4 0.0 1.5 1 0 0 1 1 1 0 ChaB WD40 PF00400.32 KNZ79943.1 - 1.2e-38 130.4 24.0 1.9e-07 31.7 0.5 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ79943.1 - 4e-22 78.3 0.4 1.8e-05 24.9 0.1 6.3 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KNZ79943.1 - 1e-10 41.8 0.8 6.8e-06 26.1 0.1 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KNZ79943.1 - 6.6e-07 28.6 0.5 0.21 10.5 0.0 4.0 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 KNZ79943.1 - 0.00018 20.7 0.1 0.00026 20.2 0.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region IKI3 PF04762.12 KNZ79943.1 - 0.0013 16.9 0.1 0.002 16.2 0.1 1.3 1 0 0 1 1 1 1 IKI3 family Nucleoporin_N PF08801.11 KNZ79943.1 - 0.0023 16.7 0.2 1.8 7.2 0.1 3.3 2 1 0 3 3 3 1 Nup133 N terminal like Frtz PF11768.8 KNZ79943.1 - 0.042 12.2 0.0 0.07 11.4 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz DPPIV_N PF00930.21 KNZ79943.1 - 0.048 12.4 0.7 0.24 10.1 0.7 2.0 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF2207 PF09972.9 KNZ79944.1 - 0.057 12.2 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kinocilin PF15033.6 KNZ79944.1 - 0.19 11.4 1.6 5.8 6.6 0.1 2.5 2 1 0 2 2 2 0 Kinocilin protein Big_10 PF17964.1 KNZ79944.1 - 0.34 10.9 3.9 0.6 10.1 3.9 1.5 1 0 0 1 1 1 0 Bacterial Ig domain Adeno_E3_CR2 PF02439.15 KNZ79945.1 - 0.097 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 KNZ79945.1 - 0.2 12.6 0.0 0.33 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain KDZ PF18758.1 KNZ79946.1 - 6.1e-46 156.8 0.0 1.1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_C48 PF02902.19 KNZ79946.1 - 2.1e-11 44.1 0.4 3.9e-11 43.2 0.4 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CxC1 PF18802.1 KNZ79946.1 - 8.6e-08 32.3 0.4 2.7e-07 30.7 0.4 1.8 1 0 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 KNZ79946.1 - 5.4e-05 23.3 0.4 5.4e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 CxC2 like cysteine cluster associated with KDZ transposases Amnionless PF14828.6 KNZ79949.1 - 0.0003 19.8 0.0 0.00039 19.4 0.0 1.0 1 0 0 1 1 1 1 Amnionless PTP_tm PF18861.1 KNZ79949.1 - 0.0013 18.8 0.1 0.0019 18.2 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J EphA2_TM PF14575.6 KNZ79949.1 - 0.044 14.7 0.0 0.068 14.1 0.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.17 KNZ79949.1 - 0.062 13.0 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 Yip1 domain Protocadherin PF08374.11 KNZ79949.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.4 1 1 0 1 1 1 0 Protocadherin Phage_HK97_TLTM PF06120.11 KNZ79949.1 - 0.16 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Gram_pos_anchor PF00746.21 KNZ79949.1 - 0.37 10.8 4.0 0.23 11.4 1.1 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif GPI-anchored PF10342.9 KNZ79950.1 - 0.0013 19.5 0.3 0.0017 19.0 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 KNZ79951.1 - 0.0074 17.0 0.1 0.01 16.5 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C3HC4_3 PF13920.6 KNZ79952.1 - 1.5e-09 37.6 8.8 1.5e-09 37.6 8.8 3.7 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.8 KNZ79952.1 - 5.4e-09 36.1 17.8 0.00087 19.5 0.3 4.7 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C3HC4_2 PF13923.6 KNZ79952.1 - 2e-08 34.0 10.7 2e-08 34.0 10.7 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ79952.1 - 4.5e-08 32.8 10.7 4.5e-08 32.8 10.7 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ79952.1 - 1.6e-07 31.2 29.0 1e-05 25.4 9.5 3.3 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.6 KNZ79952.1 - 2.1e-07 31.2 9.9 2.1e-07 31.2 9.9 3.5 2 1 1 3 3 3 1 Ring finger domain zf-met PF12874.7 KNZ79952.1 - 2.4e-06 27.7 15.7 0.045 14.2 0.3 4.9 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-rbx1 PF12678.7 KNZ79952.1 - 2e-05 24.7 5.9 2e-05 24.7 5.9 3.2 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 KNZ79952.1 - 0.00013 22.0 10.5 0.00013 22.0 10.5 3.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KNZ79952.1 - 0.00015 21.7 9.2 0.00015 21.7 9.2 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C2H2_4 PF13894.6 KNZ79952.1 - 0.00018 22.1 1.4 0.062 14.2 0.1 5.9 6 0 0 6 6 5 3 C2H2-type zinc finger Prok-RING_4 PF14447.6 KNZ79952.1 - 0.00041 20.1 25.2 0.00066 19.5 10.0 3.4 3 2 1 4 4 4 2 Prokaryotic RING finger family 4 zf-C2H2_6 PF13912.6 KNZ79952.1 - 0.00068 19.6 0.3 0.00068 19.6 0.3 4.1 5 0 0 5 5 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ79952.1 - 0.0046 17.3 1.4 0.075 13.5 0.1 4.9 5 0 0 5 5 4 2 Zinc finger, C2H2 type zf-RING_10 PF16685.5 KNZ79952.1 - 0.013 15.7 6.7 0.013 15.7 6.7 3.5 2 1 0 2 2 1 0 zinc RING finger of MSL2 FYVE PF01363.21 KNZ79952.1 - 0.19 11.9 27.5 0.61 10.3 12.1 4.2 1 1 1 2 2 2 0 FYVE zinc finger zf-RING_6 PF14835.6 KNZ79952.1 - 0.24 11.3 10.7 1.4 8.8 6.0 2.9 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KNZ79952.1 - 8.6 6.5 14.9 0.035 14.2 4.6 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M50B PF13398.6 KNZ79953.1 - 1e-53 182.0 20.3 1e-53 182.0 20.3 1.8 1 1 1 2 2 2 1 Peptidase M50B-like Ras PF00071.22 KNZ79954.1 - 2.3e-58 196.4 0.1 3e-58 196.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ79954.1 - 6.7e-31 107.0 0.1 1.1e-30 106.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ79954.1 - 3.3e-09 36.4 0.0 4.2e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.6 KNZ79954.1 - 0.00036 20.8 0.0 0.0029 17.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 KNZ79954.1 - 0.00037 20.5 0.1 0.00062 19.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KNZ79954.1 - 0.00051 19.6 0.1 0.00088 18.9 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KNZ79954.1 - 0.00085 18.7 0.0 0.0013 18.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KNZ79954.1 - 0.0041 17.1 0.1 0.53 10.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KNZ79954.1 - 0.032 14.6 0.1 0.05 14.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain YvfG PF09628.10 KNZ79954.1 - 0.15 12.5 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 YvfG protein rhaM PF05336.13 KNZ79955.1 - 1.8e-31 108.4 0.3 2e-31 108.2 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Polysacc_lyase PF14099.6 KNZ79956.1 - 0.013 15.4 0.0 0.02 14.7 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide lyase ANAPC4_WD40 PF12894.7 KNZ79957.1 - 1.5e-07 31.6 0.2 12 6.3 0.0 5.3 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ79957.1 - 6e-06 26.9 1.4 7.4 7.6 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2415 PF10313.9 KNZ79957.1 - 0.01 15.7 0.0 0.12 12.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Glyco_transf_4 PF13439.6 KNZ79958.1 - 2.2e-20 73.4 0.4 3.9e-20 72.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KNZ79958.1 - 5.4e-20 71.6 0.0 1.5e-18 66.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KNZ79958.1 - 1.5e-11 44.9 0.0 3.2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KNZ79958.1 - 6e-11 43.0 0.2 1.2e-09 38.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KNZ79958.1 - 0.04 14.3 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 ALG11_N PF15924.5 KNZ79958.1 - 0.11 12.5 0.4 8.5 6.4 0.1 3.1 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus DOPA_dioxygen PF08883.11 KNZ79959.1 - 2.3e-19 69.5 0.0 3.5e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family AA_kinase PF00696.28 KNZ79960.1 - 9.9e-43 146.5 2.0 1e-42 146.4 1.0 1.4 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 KNZ79960.1 - 6.1e-11 42.1 0.2 1.5e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 PUA domain Pribosyltran_N PF13793.6 KNZ79961.1 - 2e-50 169.6 1.2 9.1e-50 167.5 0.1 2.4 2 1 2 4 4 4 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KNZ79961.1 - 5.5e-38 130.8 3.2 6.1e-35 120.9 0.8 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KNZ79961.1 - 2.2e-19 69.5 0.4 4.4e-17 62.1 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 KNZ79961.1 - 3.6e-06 26.6 0.2 6e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 KNZ79961.1 - 0.057 12.9 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Phosphoribosyl transferase Pkinase PF00069.25 KNZ79962.1 - 2.3e-16 59.9 0.0 4.3e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79962.1 - 2.5e-08 33.5 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ79962.1 - 8.3e-05 22.6 0.0 0.00025 21.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79962.1 - 0.033 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNZ79962.1 - 0.036 12.8 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase p450 PF00067.22 KNZ79964.1 - 2e-61 208.2 0.1 3e-61 207.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2718 PF10918.8 KNZ79964.1 - 0.12 12.9 0.0 0.71 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) Methyltransf_11 PF08241.12 KNZ79965.1 - 1.4e-09 38.5 0.0 3.5e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ79965.1 - 1.9e-09 37.5 0.0 3.8e-09 36.5 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ79965.1 - 1.1e-08 35.7 0.0 5e-08 33.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ79965.1 - 1.5e-08 35.2 0.0 3.9e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ79965.1 - 2.3e-07 30.8 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ79965.1 - 1.8e-05 24.2 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family IMS PF00817.20 KNZ79966.1 - 4.5e-40 137.1 0.0 8.6e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 KNZ79966.1 - 6.9e-23 80.9 1.5 6.9e-23 80.9 1.5 1.9 2 0 0 2 2 2 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 KNZ79966.1 - 2.2e-16 60.6 0.0 8.4e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KNZ79966.1 - 3.1e-10 40.3 0.0 6.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 KNZ79966.1 - 9.4e-07 28.8 0.0 3.9e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 KNZ79966.1 - 2.5e-06 27.3 0.0 4.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KNZ79966.1 - 2.7e-06 27.7 0.0 6.8e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KNZ79966.1 - 3.9e-05 23.9 0.0 8.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain UBM PF14377.6 KNZ79966.1 - 0.026 14.0 1.7 0.72 9.4 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin binding region DUF1805 PF08827.11 KNZ79966.1 - 0.039 14.3 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) NPV_P10 PF05531.12 KNZ79967.1 - 0.037 14.5 0.4 0.38 11.2 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Clathrin_bdg PF15045.6 KNZ79967.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Asp PF00026.23 KNZ79970.1 - 1.2e-31 110.3 0.0 3e-31 109.0 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ79970.1 - 5.4e-05 23.5 1.4 0.0019 18.5 1.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ79970.1 - 0.046 14.4 0.6 0.71 10.6 0.1 2.9 3 0 0 3 3 3 0 Aspartyl protease G-alpha PF00503.20 KNZ79971.1 - 6.5e-33 114.4 0.1 7.2e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit zf-CHC2 PF01807.20 KNZ79971.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 CHC2 zinc finger zf-C2H2_4 PF13894.6 KNZ79972.1 - 0.015 16.1 0.3 0.066 14.1 0.3 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Rod_cone_degen PF15201.6 KNZ79972.1 - 0.11 12.6 0.2 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Progressive rod-cone degeneration Asp PF00026.23 KNZ79973.1 - 6.7e-17 61.9 0.2 9.2e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ketoacyl-synt PF00109.26 KNZ79973.1 - 1.9e-06 27.6 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain TAXi_N PF14543.6 KNZ79973.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal ATG13 PF10033.9 KNZ79974.1 - 2.7e-34 118.9 0.0 7.1e-34 117.6 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 13 Agenet PF05641.12 KNZ79975.1 - 0.027 14.9 0.2 0.046 14.2 0.2 1.4 1 0 0 1 1 1 0 Agenet domain Y_phosphatase3 PF13350.6 KNZ79976.1 - 1.6e-33 116.6 0.0 1.8e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KNZ79976.1 - 0.003 17.1 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Isy1 PF06246.12 KNZ79976.1 - 0.0064 16.1 0.1 0.0088 15.6 0.1 1.2 1 0 0 1 1 1 1 Isy1-like splicing family FLYWCH PF04500.16 KNZ79977.1 - 0.0073 16.4 0.4 0.015 15.4 0.4 1.5 1 0 0 1 1 1 1 FLYWCH zinc finger domain STT3 PF02516.14 KNZ79978.1 - 3.6e-62 210.9 17.3 2.6e-61 208.0 17.3 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit DDE_3 PF13358.6 KNZ79979.1 - 0.015 15.1 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Kinetochor_Ybp2 PF08568.10 KNZ79980.1 - 7.3e-12 44.6 0.0 9.1e-08 31.1 0.0 2.3 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Pkinase PF00069.25 KNZ79981.1 - 5.3e-41 140.7 0.0 7.1e-28 97.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79981.1 - 3.3e-23 82.3 0.0 4.9e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ79981.1 - 2.4e-05 23.3 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ79981.1 - 0.00066 19.7 0.2 0.0011 18.9 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ79981.1 - 0.0088 15.4 0.0 0.065 12.6 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ifi-6-16 PF06140.13 KNZ79982.1 - 5.1e-09 35.9 22.5 7.7e-09 35.4 22.5 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4781 PF16013.5 KNZ79982.1 - 3.3 6.4 4.8 3.5 6.4 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Ifi-6-16 PF06140.13 KNZ79983.1 - 4.2e-06 26.6 26.8 6e-06 26.1 26.3 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family BAG PF02179.16 KNZ79985.1 - 0.00054 20.3 0.4 0.0014 19.0 0.4 1.8 1 1 0 1 1 1 1 BAG domain Syntaxin-6_N PF09177.11 KNZ79985.1 - 0.15 12.7 0.6 4.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CLZ PF16526.5 KNZ79985.1 - 0.23 11.9 2.2 1.8 9.0 0.1 3.2 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliN_N PF16973.5 KNZ79986.1 - 0.073 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal CBF PF03914.17 KNZ79987.1 - 0.23 11.5 1.7 0.51 10.4 1.7 1.6 1 0 0 1 1 1 0 CBF/Mak21 family APH PF01636.23 KNZ79989.1 - 3.5e-11 43.5 0.8 7.6e-10 39.1 0.6 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ79989.1 - 1.1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ79989.1 - 0.028 14.0 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KNZ79990.1 - 1.9e-11 44.3 0.5 1.2e-10 41.8 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ79990.1 - 6.5e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ79990.1 - 0.0091 15.6 0.1 0.059 13.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pheromone PF08015.11 KNZ79990.1 - 0.1 13.6 0.1 0.2 12.7 0.1 1.5 1 0 0 1 1 1 0 Fungal mating-type pheromone APH PF01636.23 KNZ79991.1 - 7.9e-12 45.6 0.3 5.2e-11 42.9 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ79991.1 - 5.2e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ79991.1 - 0.0096 15.5 0.1 0.06 12.9 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pheromone PF08015.11 KNZ79991.1 - 0.1 13.7 0.1 0.21 12.7 0.1 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone Stn1 PF10451.9 KNZ79993.1 - 4.3e-07 29.1 0.0 0.0038 16.2 0.0 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 KNZ79993.1 - 0.0034 17.3 0.5 0.01 15.8 0.5 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain CH PF00307.31 KNZ79994.1 - 2e-75 250.0 0.0 3.4e-19 69.0 0.0 4.5 5 0 0 5 5 5 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 KNZ79994.1 - 2.8e-05 23.9 0.0 4.2 7.3 0.0 4.3 4 0 0 4 4 4 3 CAMSAP CH domain Bestrophin PF01062.21 KNZ79995.1 - 1.5e-37 129.6 2.6 1.1e-20 74.3 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.25 KNZ79996.1 - 6.1e-36 124.1 0.0 7.9e-36 123.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ79996.1 - 6e-34 117.5 0.0 8.5e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ79996.1 - 0.097 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 KNZ79997.1 - 1.5e-10 40.8 0.1 1.3e-05 24.7 0.0 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ79997.1 - 0.00082 18.8 0.0 0.096 12.0 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain DUF3945 PF13101.6 KNZ80000.1 - 0.16 11.7 0.1 14 5.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3945) p450 PF00067.22 KNZ80001.1 - 4.2e-67 226.9 0.0 5.9e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF5309 PF17236.2 KNZ80001.1 - 0.056 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5309) Herpes_UL6 PF01763.16 KNZ80001.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Glyco_transf_15 PF01793.16 KNZ80002.1 - 5.5e-25 88.3 0.4 6.3e-25 88.1 0.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase p450 PF00067.22 KNZ80003.1 - 9.4e-40 136.7 0.0 3.8e-23 82.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 HTH_Tnp_Tc3_2 PF01498.18 KNZ80008.1 - 9.9e-05 22.5 0.9 0.00031 20.9 0.1 2.1 1 1 1 2 2 2 1 Transposase Trp_repressor PF01371.19 KNZ80008.1 - 0.00045 20.3 0.1 0.0008 19.5 0.1 1.3 1 0 0 1 1 1 1 Trp repressor protein HTH_32 PF13565.6 KNZ80008.1 - 0.024 15.2 0.2 2.6 8.7 0.0 2.3 2 1 0 2 2 2 0 Homeodomain-like domain HTH_23 PF13384.6 KNZ80008.1 - 0.039 13.7 0.0 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain UPF0688 PF15772.5 KNZ80008.1 - 0.13 12.5 0.4 0.13 12.5 0.4 1.1 1 0 0 1 1 1 0 UPF0688 family PP-binding PF00550.25 KNZ80009.1 - 1.2e-11 44.8 0.4 1.7e-11 44.3 0.4 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KNZ80009.1 - 3.6e-06 27.1 0.2 4.8e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 Acyl-carrier Glyco_hydro_44 PF12891.7 KNZ80010.1 - 6.4e-67 225.9 3.4 1e-66 225.2 3.4 1.3 1 0 0 1 1 1 1 Glycoside hydrolase family 44 Glycos_transf_2 PF00535.26 KNZ80011.1 - 1.8e-32 112.5 0.0 2.3e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KNZ80011.1 - 3e-14 53.5 0.0 4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KNZ80011.1 - 0.00041 19.9 0.0 0.00052 19.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 KNZ80011.1 - 0.15 12.6 0.0 0.46 11.0 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 2 F-box-like PF12937.7 KNZ80012.1 - 1.5e-08 34.4 0.2 2.7e-08 33.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ80012.1 - 3.4e-06 26.8 0.1 5.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 F-box domain SMN PF06003.12 KNZ80013.1 - 0.027 13.7 13.8 0.03 13.6 0.4 3.0 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) Nic96 PF04097.14 KNZ80014.1 - 3.1e-157 524.7 0.0 4.4e-157 524.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 MCM_N PF14551.6 KNZ80014.1 - 0.38 11.4 2.7 14 6.3 0.0 3.3 4 0 0 4 4 4 0 MCM N-terminal domain SesA PF17107.5 KNZ80014.1 - 1.5 9.1 3.7 0.99 9.6 0.0 2.6 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Actin PF00022.19 KNZ80015.1 - 5.6e-47 160.2 0.0 4.9e-26 91.3 0.0 2.3 2 1 0 2 2 2 2 Actin Ras PF00071.22 KNZ80016.1 - 7.5e-64 214.2 0.1 8.8e-64 214.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ80016.1 - 8.2e-34 116.4 0.2 1.5e-33 115.6 0.1 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ80016.1 - 1.3e-13 50.8 0.1 1.7e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KNZ80016.1 - 1.8e-05 24.4 0.3 6.4e-05 22.6 0.1 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KNZ80016.1 - 4.9e-05 22.8 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ80016.1 - 8.2e-05 22.7 0.0 0.00019 21.5 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ80016.1 - 0.00011 22.2 0.0 0.29 11.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KNZ80016.1 - 0.015 15.7 0.0 0.024 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KNZ80016.1 - 0.019 14.5 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 KNZ80016.1 - 0.046 13.5 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 KNZ80016.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 KNZ80016.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KNZ80016.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 KNZ80016.1 - 0.12 12.7 0.0 0.96 9.7 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 KNZ80016.1 - 0.13 12.7 0.0 0.61 10.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 KNZ80017.1 - 2.7e-12 46.8 4.4 1.1e-10 41.6 0.5 3.0 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KNZ80017.1 - 4.2e-10 39.5 0.0 1.6e-07 31.0 0.0 2.9 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KNZ80017.1 - 1.9e-07 31.5 0.0 0.0003 21.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 KNZ80017.1 - 1.9e-06 27.6 0.0 0.028 14.2 0.1 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 KNZ80017.1 - 3.6e-05 24.0 0.0 0.00081 19.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 KNZ80017.1 - 0.065 13.3 0.0 12 6.2 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_12 PF13087.6 KNZ80017.1 - 0.14 11.8 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ80017.1 - 0.14 11.8 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 KNZ80017.1 - 9.4 6.6 12.9 12 6.2 0.4 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat DOT1 PF08123.13 KNZ80018.1 - 1.2e-61 207.9 0.0 1.5e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 KNZ80018.1 - 0.16 12.6 0.0 0.29 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.27 KNZ80019.1 - 3.5e-27 95.6 0.0 3.8e-26 92.2 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KNZ80019.1 - 8.9e-11 42.1 0.0 0.00018 21.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ80019.1 - 3.9e-06 26.8 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 KNZ80019.1 - 3.5e-05 23.3 0.0 0.031 13.7 0.2 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KNZ80019.1 - 0.00078 19.1 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 KNZ80019.1 - 0.0019 18.2 0.1 0.42 10.5 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 KNZ80019.1 - 0.0019 18.6 0.0 0.006 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 KNZ80019.1 - 0.0019 18.7 0.0 0.0049 17.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 KNZ80019.1 - 0.002 17.9 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNZ80019.1 - 0.006 16.9 0.0 0.045 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 KNZ80019.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 KNZ80019.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 KNZ80019.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 KNZ80019.1 - 0.037 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.7 KNZ80019.1 - 0.058 12.3 0.0 0.62 8.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.6 KNZ80019.1 - 0.092 13.3 0.0 0.38 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 KNZ80019.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 KNZ80019.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sel1 PF08238.12 KNZ80020.1 - 6.5e-16 58.4 10.4 2.8e-05 24.7 0.6 3.9 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 KNZ80020.1 - 0.031 14.4 6.6 0.26 11.5 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ80020.1 - 0.047 13.7 1.6 2.1 8.6 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ80020.1 - 0.054 14.3 2.1 16 6.6 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ80020.1 - 0.069 13.8 2.1 0.87 10.3 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ80020.1 - 0.077 12.9 0.4 5.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ80020.1 - 8.4 6.9 6.4 6.4 7.3 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HA2 PF04408.23 KNZ80021.1 - 8.5e-23 80.7 2.8 4e-22 78.5 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KNZ80021.1 - 9e-15 54.8 0.0 2.2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KNZ80021.1 - 5.9e-13 49.1 0.0 1.3e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNZ80021.1 - 5e-09 36.2 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KNZ80021.1 - 1.7e-05 25.1 0.4 6.3e-05 23.3 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ80021.1 - 0.00019 21.2 0.0 0.00052 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ80021.1 - 0.00074 19.9 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KNZ80021.1 - 0.0016 17.6 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 KNZ80021.1 - 0.0022 17.3 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KNZ80021.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 KaiC ResIII PF04851.15 KNZ80021.1 - 0.02 14.9 0.0 7.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KNZ80021.1 - 0.045 13.8 0.1 0.38 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KNZ80021.1 - 0.046 14.2 0.0 0.17 12.4 0.0 2.0 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KNZ80021.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Rhodanese PF00581.20 KNZ80021.1 - 0.052 14.1 0.0 0.23 12.0 0.0 2.1 2 0 0 2 2 2 0 Rhodanese-like domain IstB_IS21 PF01695.17 KNZ80021.1 - 0.063 13.0 0.0 8.9 6.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 KNZ80021.1 - 0.063 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Microtub_bd PF16796.5 KNZ80021.1 - 0.065 13.2 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_24 PF13479.6 KNZ80021.1 - 0.085 12.6 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KNZ80021.1 - 0.094 12.9 0.0 0.41 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KNZ80021.1 - 0.11 12.4 0.2 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Thiolase_N PF00108.23 KNZ80022.1 - 6.3e-12 45.4 0.1 2.6e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KNZ80022.1 - 1.4e-05 24.7 0.3 5.9e-05 22.7 0.0 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KNZ80022.1 - 0.0019 17.8 1.9 0.38 10.3 0.2 2.5 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KNZ80022.1 - 0.0035 17.2 0.0 0.24 11.3 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SURF6 PF04935.12 KNZ80023.1 - 1.3e-43 149.1 44.7 1.3e-43 149.1 44.7 2.1 2 0 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 KNZ80023.1 - 3.7e-17 62.7 2.7 3.7e-17 62.7 2.7 4.4 3 1 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 DUF1510 PF07423.11 KNZ80023.1 - 2.3 8.4 8.4 0.19 11.9 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1510) RFC1 PF08519.12 KNZ80024.1 - 1.7e-51 174.5 0.1 1.9e-50 171.1 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KNZ80024.1 - 9.3e-15 54.8 0.0 2.5e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KNZ80024.1 - 3.1e-08 34.1 0.1 7.9e-08 32.8 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KNZ80024.1 - 7e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KNZ80024.1 - 0.0016 18.4 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 KNZ80024.1 - 0.016 15.3 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KNZ80024.1 - 0.048 14.0 0.0 0.21 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA C-terminal domain NTPase_1 PF03266.15 KNZ80024.1 - 0.078 12.9 0.4 0.34 10.8 0.2 2.1 1 1 0 2 2 2 0 NTPase RuvB_N PF05496.12 KNZ80024.1 - 0.098 12.4 0.0 0.35 10.6 0.0 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 KNZ80024.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_22 PF13401.6 KNZ80024.1 - 0.13 12.5 0.2 1.6 9.0 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ80024.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KNZ80024.1 - 0.14 12.1 0.1 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 KNZ80024.1 - 0.16 12.2 1.0 0.69 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_60s PF00428.19 KNZ80025.1 - 0.013 16.1 5.4 0.019 15.5 5.4 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3682 PF12446.8 KNZ80025.1 - 0.57 10.7 4.6 0.81 10.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) zf-RVT PF13966.6 KNZ80026.1 - 0.00046 20.9 3.8 0.00067 20.3 3.8 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_M1 PF01433.20 KNZ80027.1 - 7.2e-35 120.5 0.1 9.6e-35 120.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KNZ80027.1 - 1.8e-29 102.1 0.0 4.6e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KNZ80027.1 - 5.8e-20 72.3 0.0 9.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 KNZ80027.1 - 0.083 13.3 3.0 2.2 8.7 3.0 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase adh_short_C2 PF13561.6 KNZ80028.1 - 2.5e-63 213.8 0.1 4.8e-63 212.8 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Proteasome PF00227.26 KNZ80028.1 - 3.5e-53 179.9 0.1 7.7e-53 178.8 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit adh_short PF00106.25 KNZ80028.1 - 8.4e-46 155.9 0.1 1.3e-45 155.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Proteasome_A_N PF10584.9 KNZ80028.1 - 5.8e-12 45.1 0.1 5.8e-12 45.1 0.1 2.5 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature KR PF08659.10 KNZ80028.1 - 1.8e-05 24.7 0.1 4.2e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KNZ80028.1 - 0.12 12.3 1.2 0.18 11.7 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5349 PF17298.2 KNZ80028.1 - 2.3 7.9 12.1 0.033 14.0 3.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5349) DUF962 PF06127.11 KNZ80029.1 - 1.5e-23 82.6 0.1 3e-23 81.7 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Longin PF13774.6 KNZ80030.1 - 1.1e-24 86.3 0.1 1.9e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF4646 PF15496.6 KNZ80030.1 - 1.3e-07 32.3 0.3 0.00076 20.1 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4646) Synaptobrevin PF00957.21 KNZ80030.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin CDC45 PF02724.14 KNZ80030.1 - 0.78 8.0 2.9 1.3 7.2 2.9 1.2 1 0 0 1 1 1 0 CDC45-like protein NINJA_B PF16136.5 KNZ80030.1 - 1.9 8.9 9.7 0.59 10.5 6.1 2.0 2 0 0 2 2 2 0 Putative nuclear localisation signal DUF1043 PF06295.12 KNZ80030.1 - 3.6 7.6 5.0 0.72 9.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) XRN_M PF17846.1 KNZ80031.1 - 8.5e-142 473.2 0.4 5.5e-103 345.3 0.0 2.7 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 KNZ80031.1 - 1.1e-51 175.6 7.4 5.5e-39 134.0 0.5 2.5 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus SUIM_assoc PF16619.5 KNZ80031.1 - 1.6 8.8 4.1 5 7.3 4.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 IF-2B PF01008.17 KNZ80032.1 - 1.2e-78 264.2 0.0 1.4e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family MTP18 PF10558.9 KNZ80033.1 - 4.6e-64 215.5 5.6 8.5e-63 211.4 5.6 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Forkhead PF00250.18 KNZ80034.1 - 1.5e-27 95.6 0.1 2.7e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KNZ80034.1 - 2.3e-06 27.8 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain IPK PF03770.16 KNZ80035.1 - 1.8e-53 181.4 0.0 2.9e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase CENP-Q PF13094.6 KNZ80036.1 - 0.0028 17.9 2.3 0.0051 17.0 2.3 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PKcGMP_CC PF16808.5 KNZ80036.1 - 0.011 15.6 5.3 0.011 15.6 5.3 2.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase V-ATPase_G_2 PF16999.5 KNZ80036.1 - 0.16 12.4 5.3 0.28 11.6 5.3 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF4337 PF14235.6 KNZ80036.1 - 0.39 10.8 2.2 0.69 10.0 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HIP1_clath_bdg PF16515.5 KNZ80036.1 - 0.45 11.2 9.3 0.86 10.2 9.3 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 KNZ80036.1 - 0.61 9.4 3.2 0.89 8.8 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 KNZ80036.1 - 9.9 6.9 12.0 18 6.1 3.5 2.6 1 1 1 2 2 2 0 SlyX Med18 PF09637.10 KNZ80038.1 - 8.2e-05 22.6 0.0 0.0016 18.3 0.0 2.0 1 1 0 2 2 2 2 Med18 protein zf-HIT PF04438.16 KNZ80039.1 - 2.1e-05 24.3 13.5 3e-05 23.8 13.5 1.2 1 0 0 1 1 1 1 HIT zinc finger CIAPIN1 PF05093.13 KNZ80040.1 - 4.8e-31 107.3 4.0 7e-31 106.7 4.0 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Forkhead PF00250.18 KNZ80041.1 - 4e-31 107.1 0.0 6e-31 106.5 0.0 1.2 1 0 0 1 1 1 1 Forkhead domain DUF3402 PF11882.8 KNZ80042.1 - 5.5e-121 404.9 0.1 1.5e-119 400.2 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KNZ80042.1 - 5.1e-75 252.3 0.0 8.5e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Cyclin PF08613.11 KNZ80043.1 - 2.4e-05 24.8 0.0 4.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin LssY_C PF14067.6 KNZ80043.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 LssY C-terminus ThiF PF00899.21 KNZ80044.1 - 5.5e-109 363.2 0.0 1.2e-69 234.4 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KNZ80044.1 - 4.2e-89 298.8 0.0 6.5e-89 298.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KNZ80044.1 - 1.9e-35 120.9 0.4 4.5e-35 119.7 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KNZ80044.1 - 4.2e-31 107.5 0.3 8.4e-31 106.5 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KNZ80044.1 - 9.8e-26 89.8 0.0 2.4e-25 88.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 KNZ80044.1 - 0.096 12.7 0.2 0.43 10.6 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cactin_mid PF10312.9 KNZ80045.1 - 1.1e-65 221.0 2.6 1.1e-65 221.0 2.6 2.6 4 0 0 4 4 4 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KNZ80045.1 - 2.2e-60 202.1 5.9 5.6e-60 200.8 5.9 1.7 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein BsuPI PF12690.7 KNZ80045.1 - 0.079 13.0 0.6 0.42 10.7 0.2 2.3 2 0 0 2 2 2 0 Intracellular proteinase inhibitor AAA_2 PF07724.14 KNZ80046.1 - 3.8e-34 118.3 0.0 2.2e-33 115.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KNZ80046.1 - 6.8e-12 45.9 0.0 2.6e-11 44.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KNZ80046.1 - 7.9e-11 41.9 0.0 1.6e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.21 KNZ80046.1 - 2.7e-05 23.6 0.1 0.00078 18.9 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KNZ80046.1 - 6.6e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KNZ80046.1 - 0.0001 22.6 0.1 0.00056 20.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 KNZ80046.1 - 0.0017 17.4 0.0 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 KNZ80046.1 - 0.0039 17.6 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 KNZ80046.1 - 0.0053 15.9 0.1 5.3 6.1 0.1 3.5 3 1 0 3 3 3 1 MCM P-loop domain Sigma54_activat PF00158.26 KNZ80046.1 - 0.0054 16.5 0.0 0.015 15.0 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 KNZ80046.1 - 0.0074 16.0 0.0 0.019 14.7 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 KNZ80046.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 KNZ80046.1 - 0.013 16.0 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DEAD PF00270.29 KNZ80046.1 - 0.023 14.5 0.0 0.11 12.3 0.0 2.0 3 0 0 3 3 2 0 DEAD/DEAH box helicase RuvB_N PF05496.12 KNZ80046.1 - 0.023 14.4 0.1 0.19 11.4 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KNZ80046.1 - 0.029 14.4 0.0 0.078 13.0 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 KNZ80046.1 - 0.034 14.3 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain HeH PF12949.7 KNZ80046.1 - 0.035 13.8 0.1 0.089 12.5 0.1 1.7 1 0 0 1 1 1 0 HeH/LEM domain NACHT PF05729.12 KNZ80046.1 - 0.04 13.9 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KNZ80046.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 KNZ80046.1 - 0.044 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.6 KNZ80046.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KNZ80046.1 - 0.087 13.2 0.0 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.11 KNZ80046.1 - 0.091 12.6 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KNZ80046.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KNZ80046.1 - 0.12 12.7 0.1 0.74 10.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KNZ80046.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 KNZ80046.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ran_BP1 PF00638.18 KNZ80047.1 - 6.1e-32 110.4 0.3 8.4e-32 110.0 0.3 1.2 1 0 0 1 1 1 1 RanBP1 domain EMP24_GP25L PF01105.24 KNZ80048.1 - 1.4e-46 158.7 0.4 1.7e-46 158.5 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kinesin PF00225.23 KNZ80049.1 - 7.2e-89 298.0 0.0 1.5e-88 296.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ80049.1 - 5.1e-12 46.0 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Macoilin PF09726.9 KNZ80049.1 - 0.0018 16.9 1.3 0.0037 15.9 1.3 1.5 1 0 0 1 1 1 1 Macoilin family AAA_13 PF13166.6 KNZ80049.1 - 0.15 10.7 4.8 0.34 9.5 4.8 1.5 1 0 0 1 1 1 0 AAA domain DUF2347 PF09804.9 KNZ80049.1 - 0.29 10.7 2.5 1.2 8.7 0.4 2.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2347) ZapB PF06005.12 KNZ80049.1 - 9.2 6.8 11.2 0.55 10.7 2.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Amidohydro_1 PF01979.20 KNZ80050.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KNZ80050.1 - 1.1e-06 28.6 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase zf-RVT PF13966.6 KNZ80053.1 - 0.01 16.5 0.8 0.022 15.4 0.8 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase GAS2 PF02187.17 KNZ80054.1 - 7.4e-12 45.2 0.0 2.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Iso_dh PF00180.20 KNZ80056.1 - 5.4e-99 331.6 0.0 6.1e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WD40 PF00400.32 KNZ80057.1 - 8.9e-21 73.8 14.8 4.1e-07 30.6 0.5 6.5 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ80057.1 - 5.6e-07 29.8 0.2 1.9e-05 24.9 0.1 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NmrA PF05368.13 KNZ80058.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KNZ80058.1 - 3.5e-06 27.0 0.0 4.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KNZ80058.1 - 0.0011 19.1 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 KNZ80058.1 - 0.0037 16.7 0.0 0.0082 15.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 KNZ80058.1 - 0.042 14.3 0.0 0.099 13.1 0.0 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 KNZ80058.1 - 0.063 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain KR PF08659.10 KNZ80058.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 KR domain UDPG_MGDP_dh_N PF03721.14 KNZ80058.1 - 0.15 11.7 2.9 0.54 9.8 0.7 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Arf PF00025.21 KNZ80059.1 - 8e-72 240.3 0.0 9.5e-72 240.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KNZ80059.1 - 2.5e-15 56.3 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KNZ80059.1 - 1.1e-14 54.4 0.1 8e-09 35.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KNZ80059.1 - 2.4e-13 50.4 0.0 3.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KNZ80059.1 - 4.1e-10 39.5 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KNZ80059.1 - 1.2e-09 37.9 0.0 1.5e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ80059.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ80059.1 - 0.13 11.8 0.2 0.4 10.2 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 KNZ80059.1 - 0.2 11.0 0.0 0.55 9.5 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF2373 PF10180.9 KNZ80060.1 - 1.3e-15 57.0 0.1 1.9e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) MAT1 PF06391.13 KNZ80060.1 - 0.45 10.3 9.1 1.6 8.5 5.4 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 cwf21 PF08312.12 KNZ80061.1 - 4.5e-15 55.5 9.1 4.5e-15 55.5 9.1 2.3 3 1 0 3 3 3 1 cwf21 domain Abhydrolase_1 PF00561.20 KNZ80062.1 - 1.3e-24 87.2 0.0 2.2e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ80062.1 - 2.6e-17 62.9 0.0 2.7e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ80062.1 - 3.5e-16 60.5 0.4 6.9e-16 59.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KNZ80062.1 - 3e-05 23.7 0.0 7.6e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 KNZ80062.1 - 0.00035 20.5 0.0 0.022 14.6 0.1 2.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KNZ80062.1 - 0.00035 20.3 0.0 0.00085 19.0 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 KNZ80062.1 - 0.001 17.8 0.0 0.0025 16.6 0.0 1.5 2 0 0 2 2 2 1 Ndr family Ser_hydrolase PF06821.13 KNZ80062.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 KNZ80062.1 - 0.0029 17.6 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 KNZ80062.1 - 0.027 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.16 KNZ80062.1 - 0.14 11.9 0.0 11 5.7 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 KNZ80062.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MT-A70 PF05063.14 KNZ80063.1 - 1.4e-53 181.4 0.1 1.8e-53 181.0 0.1 1.2 1 0 0 1 1 1 1 MT-A70 ImpA_N PF06812.12 KNZ80064.1 - 0.065 13.3 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Bacillus_HBL PF05791.11 KNZ80064.1 - 0.11 12.4 0.6 0.18 11.6 0.6 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) adh_short PF00106.25 KNZ80065.1 - 1.6e-08 34.2 0.0 2.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ80065.1 - 6.1e-07 29.2 0.0 7.6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Spore_YhaL PF14147.6 KNZ80066.1 - 2.7 7.8 7.0 0.2 11.4 1.5 2.1 2 0 0 2 2 2 0 Sporulation protein YhaL MpPF26 PF07666.11 KNZ80066.1 - 9.5 6.3 19.8 0.24 11.5 11.1 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 Acetyltransf_2 PF00797.17 KNZ80067.1 - 1.4e-29 103.6 0.0 2.5e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase CAP59_mtransfer PF11735.8 KNZ80068.1 - 2.3e-69 233.8 0.1 2.7e-69 233.5 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Acetyltransf_2 PF00797.17 KNZ80072.1 - 4e-19 69.3 0.0 5e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Raco_middle PF17651.1 KNZ80072.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 RACo middle region TPR_12 PF13424.6 KNZ80074.1 - 6.5e-10 39.2 12.1 0.0089 16.3 0.0 4.4 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ80074.1 - 3e-07 30.1 11.4 0.32 11.2 0.2 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ80074.1 - 3.2e-07 30.0 7.1 0.036 13.4 1.5 3.5 1 1 1 3 3 3 2 MalT-like TPR region AAA_22 PF13401.6 KNZ80074.1 - 1.3e-05 25.5 0.2 0.00011 22.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.28 KNZ80074.1 - 1.8e-05 24.4 3.8 4.3 7.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.22 KNZ80074.1 - 8.3e-05 21.9 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KNZ80074.1 - 0.00096 19.6 0.9 0.0073 16.7 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.6 KNZ80074.1 - 0.0012 19.5 4.4 17 6.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_24 PF13479.6 KNZ80074.1 - 0.0017 18.1 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ80074.1 - 0.0021 18.5 1.8 0.0051 17.2 0.0 2.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) ANAPC5 PF12862.7 KNZ80074.1 - 0.019 15.0 0.8 0.07 13.2 0.8 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 MMR_HSR1 PF01926.23 KNZ80074.1 - 0.064 13.3 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3206 PF11472.8 KNZ80074.1 - 0.085 12.9 0.2 0.27 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) TPR_16 PF13432.6 KNZ80074.1 - 0.17 12.5 8.2 27 5.5 0.1 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ80074.1 - 2.4 8.7 14.6 17 6.0 2.4 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat EFG_C PF00679.24 KNZ80075.1 - 6.5e-16 58.1 0.1 1.2e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ80075.1 - 0.023 15.1 0.1 0.056 13.8 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Aldedh PF00171.22 KNZ80076.1 - 5.9e-27 94.3 0.1 6.9e-27 94.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Chorion_2 PF03964.15 KNZ80076.1 - 0.12 13.3 0.1 0.15 12.9 0.1 1.3 1 0 0 1 1 1 0 Chorion family 2 AAA_22 PF13401.6 KNZ80077.1 - 1.7e-06 28.3 0.1 6.3e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KNZ80077.1 - 2.9e-05 24.5 0.2 0.00026 21.4 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KNZ80077.1 - 4.3e-05 22.8 0.0 9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 KNZ80077.1 - 0.0021 17.8 0.0 0.0055 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ80077.1 - 0.0032 17.9 0.0 0.0094 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KNZ80077.1 - 0.03 14.1 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 KNZ80077.1 - 0.034 14.1 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Homoserine_dh PF00742.19 KNZ80077.1 - 0.044 13.7 0.6 0.12 12.2 0.2 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase DUF815 PF05673.13 KNZ80077.1 - 0.095 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KNZ80077.1 - 0.11 13.0 0.6 0.52 10.8 0.0 2.4 3 1 0 3 3 3 0 ABC transporter MMR_HSR1 PF01926.23 KNZ80077.1 - 0.11 12.5 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Tudor_3 PF18115.1 KNZ80077.1 - 0.37 10.7 1.3 0.59 10.0 0.2 1.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain EFG_C PF00679.24 KNZ80078.1 - 6.7e-10 38.9 0.0 1.3e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ80078.1 - 0.1 13.0 0.5 0.27 11.6 0.5 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Aldedh PF00171.22 KNZ80079.1 - 6.2e-17 61.2 0.1 7.2e-17 61.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NAD_binding_4 PF07993.12 KNZ80080.1 - 0.0033 16.6 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Pkinase PF00069.25 KNZ80081.1 - 7.9e-17 61.5 0.2 1.5e-11 44.2 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80081.1 - 0.051 12.8 0.3 0.11 11.7 0.2 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Asp_protease_2 PF13650.6 KNZ80083.1 - 0.002 18.8 0.0 0.0044 17.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ80083.1 - 0.0041 17.6 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease CDV3 PF15359.6 KNZ80083.1 - 1.9 9.0 6.3 3.5 8.1 6.3 1.5 1 1 0 1 1 1 0 Carnitine deficiency-associated protein 3 Endonuc-HincII PF09226.11 KNZ80085.1 - 0.039 13.2 2.7 0.041 13.2 2.7 1.0 1 0 0 1 1 1 0 Restriction endonuclease HincII Mem_trans PF03547.18 KNZ80086.1 - 5.5e-34 117.2 11.8 9.3e-27 93.4 1.1 2.9 2 1 0 2 2 2 2 Membrane transport protein YhhN PF07947.14 KNZ80086.1 - 0.001 18.7 2.8 0.0041 16.7 2.8 2.0 1 0 0 1 1 1 1 YhhN family US30 PF17624.2 KNZ80086.1 - 0.099 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function SPX PF03105.19 KNZ80086.1 - 1.2 8.9 2.6 1.6 8.5 2.6 1.1 1 0 0 1 1 1 0 SPX domain PCMT PF01135.19 KNZ80087.1 - 1.2e-68 231.0 0.0 1.5e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KNZ80087.1 - 1.2e-06 28.3 0.0 1.9e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KNZ80087.1 - 2.5e-05 24.1 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.6 KNZ80087.1 - 0.00014 22.5 0.0 0.00039 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ80087.1 - 0.00073 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KNZ80087.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ80087.1 - 0.0025 18.4 0.1 0.0058 17.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ80087.1 - 0.006 15.9 0.0 0.0083 15.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 KNZ80087.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 KNZ80087.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KNZ80087.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Fibrillarin PF01269.17 KNZ80087.1 - 0.1 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_18 PF12847.7 KNZ80087.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_1 PF00036.32 KNZ80087.1 - 0.17 11.5 0.0 0.45 10.2 0.0 1.7 1 0 0 1 1 1 0 EF hand RVT_1 PF00078.27 KNZ80089.1 - 5.9e-05 22.7 0.2 9.5e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.24 KNZ80089.1 - 0.038 13.9 0.3 0.15 12.0 0.3 2.1 1 1 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease PF09668.10 KNZ80090.1 - 0.11 12.3 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Aspartyl protease Oxidored_FMN PF00724.20 KNZ80092.1 - 1.7e-68 231.4 0.0 2.2e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 KNZ80092.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.20 KNZ80093.1 - 3.2e-31 108.8 0.0 4.5e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family LRR_6 PF13516.6 KNZ80094.1 - 2.6e-06 27.0 19.9 0.6 10.3 0.1 6.0 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 KNZ80094.1 - 8.5 7.4 8.6 13 6.8 0.3 4.5 4 1 0 4 4 4 0 Leucine Rich Repeat Glyco_hydro_53 PF07745.13 KNZ80095.1 - 6.1e-79 265.5 0.0 4.3e-78 262.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KNZ80095.1 - 0.00092 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MHC_I_2 PF14586.6 KNZ80095.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 zf-RING_2 PF13639.6 KNZ80097.1 - 1.2e-11 44.8 3.9 1.2e-11 44.8 3.9 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 KNZ80097.1 - 1.1e-07 32.0 7.3 6.7e-07 29.5 7.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KNZ80097.1 - 2.7e-07 30.3 3.5 6.1e-07 29.2 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KNZ80097.1 - 1.1e-05 25.1 1.1 1.1e-05 25.1 1.1 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KNZ80097.1 - 4e-05 23.4 1.9 7.9e-05 22.5 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ80097.1 - 5e-05 23.2 3.5 9.5e-05 22.3 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KNZ80097.1 - 0.00026 20.8 2.5 0.0005 19.9 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ80097.1 - 0.00097 19.1 1.7 0.0027 17.7 1.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KNZ80097.1 - 0.0013 18.8 4.4 0.005 16.9 4.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KNZ80097.1 - 0.0035 16.9 3.0 0.007 16.0 3.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KNZ80097.1 - 0.0062 16.7 2.5 0.015 15.4 2.5 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 KNZ80097.1 - 0.12 12.2 3.1 0.26 11.2 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 KNZ80097.1 - 0.33 11.1 3.8 0.69 10.1 3.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 KNZ80097.1 - 0.38 11.1 1.5 0.72 10.2 1.5 1.4 1 0 0 1 1 1 0 RING-like domain Sec23_trunk PF04811.15 KNZ80098.1 - 5.4e-77 258.6 0.0 9.1e-77 257.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KNZ80098.1 - 8.9e-30 103.3 0.3 2e-29 102.2 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KNZ80098.1 - 2e-25 88.6 0.2 4.5e-25 87.4 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KNZ80098.1 - 1.3e-15 57.1 6.4 2.5e-15 56.2 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KNZ80098.1 - 2.5e-13 49.7 0.0 1.7e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KNZ80098.1 - 0.093 12.1 0.2 0.24 10.8 0.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Cnd3 PF12719.7 KNZ80100.1 - 1.4e-81 273.9 5.4 2.3e-81 273.2 3.8 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 KNZ80100.1 - 0.0088 16.5 0.1 0.12 12.9 0.0 3.1 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.22 KNZ80100.1 - 0.0096 16.1 0.2 17 6.0 0.1 4.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 KNZ80100.1 - 0.011 16.1 2.7 0.22 11.9 0.1 3.8 3 1 1 4 4 4 0 HEAT repeats DUF1770 PF08589.10 KNZ80101.1 - 2.3e-08 34.9 0.5 2.3e-08 34.9 0.5 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) CcmD PF04995.14 KNZ80102.1 - 0.073 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) p450 PF00067.22 KNZ80104.1 - 1.1e-73 248.5 0.0 4e-73 246.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 GST_N_2 PF13409.6 KNZ80106.1 - 4e-23 81.5 0.2 4e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ80106.1 - 1.3e-14 54.0 0.1 4.6e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ80106.1 - 9.5e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ80106.1 - 6.5e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KNZ80106.1 - 9.7e-05 22.7 0.2 0.0026 18.1 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Nup96 PF12110.8 KNZ80108.1 - 1.2e-86 290.5 0.0 1.7e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 FRG2 PF15315.6 KNZ80108.1 - 0.13 12.5 5.8 0.23 11.7 5.8 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Glyco_hydro_16 PF00722.21 KNZ80109.1 - 3.6e-08 33.1 0.0 6.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 UQ_con PF00179.26 KNZ80111.1 - 2.8e-48 163.1 0.0 3.1e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KNZ80111.1 - 0.0048 17.2 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 KNZ80111.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KNZ80111.1 - 0.023 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain OPT PF03169.15 KNZ80112.1 - 1.1e-93 315.0 39.3 1.4e-93 314.6 39.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PWI PF01480.17 KNZ80113.1 - 5.9e-29 100.2 0.1 1e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 PWI domain EMP24_GP25L PF01105.24 KNZ80114.1 - 5.7e-39 133.9 0.0 6.5e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 KNZ80114.1 - 0.0064 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Trimerisation motif TRPM_tetra PF16519.5 KNZ80114.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Laminin_II PF06009.12 KNZ80114.1 - 0.098 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II Dak1 PF02733.17 KNZ80115.1 - 1.7e-101 339.2 0.1 2.6e-101 338.6 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 KNZ80115.1 - 1.1e-41 142.6 1.8 1.8e-41 142.0 1.8 1.3 1 0 0 1 1 1 1 DAK2 domain DUF685 PF05085.12 KNZ80115.1 - 0.2 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF685) UCH PF00443.29 KNZ80116.1 - 1.6e-71 240.9 0.0 2.1e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KNZ80116.1 - 1.5e-17 64.0 0.2 9.7e-17 61.4 0.0 2.5 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 KNZ80116.1 - 5.8e-12 45.8 0.0 4.4e-05 23.2 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PhnA_Zn_Ribbon PF08274.12 KNZ80116.1 - 0.22 11.5 1.7 15 5.6 0.1 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Sugar_tr PF00083.24 KNZ80117.1 - 1.1e-135 453.0 20.6 1.3e-135 452.8 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ80117.1 - 5.3e-23 81.5 57.3 1.8e-21 76.5 29.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 KNZ80117.1 - 0.066 13.0 1.5 3.7 7.4 0.2 3.4 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Cyto_heme_lyase PF01265.17 KNZ80118.1 - 1.3e-73 248.1 7.8 6.7e-72 242.5 7.8 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase LPD11 PF18824.1 KNZ80118.1 - 0.021 14.9 0.8 1.9 8.6 0.4 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 Tim44 PF04280.15 KNZ80119.1 - 2.7e-33 115.2 0.5 2.7e-33 115.2 0.5 1.9 2 0 0 2 2 2 1 Tim44-like domain DUF3813 PF12758.7 KNZ80119.1 - 0.044 14.1 8.6 1.1 9.7 3.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) KIF1B PF12423.8 KNZ80119.1 - 0.14 12.6 0.2 0.45 11.0 0.2 1.9 1 0 0 1 1 1 0 Kinesin protein 1B DMPK_coil PF08826.10 KNZ80119.1 - 0.25 11.5 5.7 0.32 11.1 0.4 2.9 1 1 1 2 2 2 0 DMPK coiled coil domain like BORCS7 PF16088.5 KNZ80119.1 - 0.34 11.2 3.4 0.28 11.5 1.3 2.0 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 T3SS_basalb_I PF17001.5 KNZ80119.1 - 3.6 8.2 6.8 13 6.4 0.1 3.2 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Ribosomal_S20p PF01649.18 KNZ80119.1 - 5.5 7.7 9.8 0.14 12.8 0.5 2.9 3 1 1 4 4 4 0 Ribosomal protein S20 DUF2203 PF09969.9 KNZ80119.1 - 7.8 7.2 9.4 1.1 9.9 2.7 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) PIG-P PF08510.12 KNZ80120.1 - 0.27 11.2 4.5 0.78 9.7 0.4 2.4 2 0 0 2 2 2 0 PIG-P UL45 PF05473.12 KNZ80120.1 - 2.3 7.8 7.9 6.8 6.3 1.1 2.2 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like p450 PF00067.22 KNZ80121.1 - 3.8e-56 190.8 0.0 5e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SARS_X4 PF08779.10 KNZ80121.1 - 0.089 13.0 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 SARS coronavirus X4 like FemAB_like PF04339.12 KNZ80121.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition PIF1 PF05970.14 KNZ80122.1 - 8.8e-61 206.1 1.8 1.1e-47 162.9 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KNZ80122.1 - 4.4e-22 78.7 0.0 7.6e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ80122.1 - 2.1e-13 50.9 0.0 4.6e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KNZ80122.1 - 1e-06 27.1 0.2 1.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 KNZ80122.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 KNZ80122.1 - 0.00017 21.2 0.0 0.00041 19.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 KNZ80122.1 - 0.00019 21.7 0.4 0.00063 20.0 0.1 2.0 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ80122.1 - 0.0006 19.6 0.5 0.61 9.8 0.3 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KNZ80122.1 - 0.0015 19.0 0.3 0.009 16.4 0.1 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KNZ80122.1 - 0.0022 18.4 0.0 0.0046 17.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KNZ80122.1 - 0.011 15.6 1.1 0.2 11.5 1.1 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KNZ80122.1 - 0.016 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 KNZ80122.1 - 0.016 14.5 0.5 0.087 12.0 0.2 2.4 2 1 1 3 3 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 KNZ80122.1 - 0.016 15.2 1.2 0.57 10.2 0.2 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Muraidase PF11860.8 KNZ80122.1 - 0.025 14.8 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramidase IstB_IS21 PF01695.17 KNZ80122.1 - 0.026 14.3 0.3 5.1 6.8 0.0 2.4 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 KNZ80122.1 - 0.028 13.9 0.0 0.091 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KNZ80122.1 - 0.03 14.4 0.1 0.16 12.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain SH3_13 PF18335.1 KNZ80122.1 - 0.036 13.9 0.1 0.084 12.7 0.1 1.6 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain AAA_33 PF13671.6 KNZ80122.1 - 0.04 14.1 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KNZ80122.1 - 0.047 13.6 0.1 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 NTPase Helicase_RecD PF05127.14 KNZ80122.1 - 0.05 13.4 0.3 0.21 11.4 0.3 2.0 1 1 0 1 1 1 0 Helicase DUF5605 PF18310.1 KNZ80122.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5605) AAA_11 PF13086.6 KNZ80122.1 - 0.069 12.9 0.3 2.7 7.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 KNZ80122.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 KNZ80122.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 KNZ80122.1 - 0.076 12.1 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.21 KNZ80122.1 - 0.078 12.5 0.9 0.15 11.6 0.3 1.7 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.27 KNZ80122.1 - 0.092 13.3 0.2 0.72 10.4 0.1 2.4 2 1 0 3 3 3 0 ABC transporter NB-ARC PF00931.22 KNZ80122.1 - 0.094 11.9 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KNZ80122.1 - 0.098 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_32 PF13654.6 KNZ80122.1 - 0.1 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4440 PF14534.6 KNZ80122.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DEAD PF00270.29 KNZ80122.1 - 0.14 11.9 0.3 1.2 8.8 0.1 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 KNZ80122.1 - 0.15 12.5 0.0 0.47 10.9 0.0 1.9 1 1 0 1 1 1 0 RNA helicase COesterase PF00135.28 KNZ80123.1 - 7.9e-78 262.6 0.0 1.1e-77 262.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ80123.1 - 1.5e-08 34.8 1.5 3.6e-08 33.5 0.5 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ80123.1 - 0.03 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KNZ80123.1 - 0.26 10.1 0.0 11 4.8 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase WEMBL PF05701.11 KNZ80124.1 - 0.05 12.3 0.8 0.069 11.8 0.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF1295 PF06966.12 KNZ80125.1 - 3.4e-38 131.5 10.2 2.3e-36 125.5 10.2 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 KNZ80125.1 - 0.014 15.8 1.6 0.025 15.0 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KNZ80125.1 - 0.02 15.3 2.4 0.025 15.0 0.0 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase PYC_OADA PF02436.18 KNZ80126.1 - 0.4 10.4 2.9 0.74 9.5 2.9 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain Rcd1 PF04078.13 KNZ80127.1 - 3e-117 390.5 1.9 4.1e-117 390.1 1.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like OSCP PF00213.18 KNZ80127.1 - 0.16 12.0 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit FA_hydroxylase PF04116.13 KNZ80128.1 - 1.5e-23 83.6 8.9 1.5e-23 83.6 8.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3561 PF12084.8 KNZ80128.1 - 0.89 9.6 6.2 1.2 9.2 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3561) Ribosomal_L28e PF01778.17 KNZ80129.1 - 2e-33 115.5 0.6 2e-33 115.5 0.6 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 KNZ80129.1 - 4e-29 101.2 13.1 4e-29 101.2 13.1 2.1 2 0 0 2 2 2 1 Mak16 protein C-terminal region RVT_1 PF00078.27 KNZ80129.1 - 2.7e-07 30.3 0.4 5.2e-07 29.4 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BUD22 PF09073.10 KNZ80129.1 - 0.23 10.8 24.4 0.42 9.9 24.3 1.3 1 1 0 1 1 1 0 BUD22 AMP-binding PF00501.28 KNZ80130.1 - 6.4e-94 314.9 0.4 8.4e-94 314.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ80130.1 - 6e-26 91.2 0.1 1.2e-24 87.1 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KNZ80130.1 - 7.2e-13 48.2 0.4 7.2e-13 48.2 0.4 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Retrotrans_gag PF03732.17 KNZ80131.1 - 0.024 14.9 0.4 0.048 13.9 0.3 1.6 1 1 1 2 2 2 0 Retrotransposon gag protein ATG16 PF08614.11 KNZ80132.1 - 6.9e-06 26.4 9.0 0.00018 21.8 4.9 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Taxilin PF09728.9 KNZ80132.1 - 0.00037 19.8 0.3 0.00037 19.8 0.3 1.8 2 0 0 2 2 2 1 Myosin-like coiled-coil protein HAP1_N PF04849.13 KNZ80132.1 - 0.0013 18.0 8.7 0.014 14.6 3.7 2.1 2 0 0 2 2 2 2 HAP1 N-terminal conserved region TMF_TATA_bd PF12325.8 KNZ80132.1 - 0.01 16.0 9.2 0.099 12.9 0.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 KNZ80132.1 - 0.042 14.5 7.0 3.2 8.4 3.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA FH2 PF02181.23 KNZ80132.1 - 0.049 12.8 6.1 0.34 10.0 0.2 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain Spc7 PF08317.11 KNZ80132.1 - 0.052 12.4 12.6 0.47 9.3 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Drc1-Sld2 PF11719.8 KNZ80132.1 - 0.059 12.9 4.0 0.084 12.4 0.8 2.0 1 1 1 2 2 2 0 DNA replication and checkpoint protein DUF3467 PF11950.8 KNZ80132.1 - 0.075 13.2 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) Sec8_exocyst PF04048.14 KNZ80132.1 - 0.084 12.8 4.9 0.58 10.0 0.2 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF2353 PF09789.9 KNZ80132.1 - 0.11 11.8 7.2 0.31 10.4 3.8 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) TPR_MLP1_2 PF07926.12 KNZ80132.1 - 0.13 12.4 0.2 0.13 12.4 0.2 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KNZ80132.1 - 0.13 12.7 8.2 1.1 9.8 2.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Takusan PF04822.13 KNZ80132.1 - 0.2 11.6 3.7 2.3 8.2 0.3 2.7 2 1 0 2 2 2 0 Takusan Fib_alpha PF08702.10 KNZ80132.1 - 0.46 10.7 9.0 1.6 8.9 4.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Wtap PF17098.5 KNZ80132.1 - 0.47 10.4 5.6 5.8 6.8 0.1 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family RraB PF06877.11 KNZ80132.1 - 0.64 10.8 3.7 0.26 12.0 0.8 1.8 2 0 0 2 2 1 0 Regulator of ribonuclease activity B BCAS2 PF05700.11 KNZ80132.1 - 0.84 9.3 5.8 0.81 9.3 0.1 2.3 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) Atg14 PF10186.9 KNZ80132.1 - 0.94 8.5 7.4 0.7 8.9 4.3 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 betaPIX_CC PF16523.5 KNZ80132.1 - 1 9.3 6.2 0.26 11.1 0.2 2.5 2 1 1 3 3 3 0 betaPIX coiled coil DUF4618 PF15397.6 KNZ80132.1 - 2 7.8 10.2 0.69 9.3 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF1664 PF07889.12 KNZ80132.1 - 3.2 7.8 11.3 2.9 7.9 4.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 KNZ80132.1 - 3.6 8.1 14.2 11 6.5 1.3 2.5 2 0 0 2 2 2 0 Snapin/Pallidin KxDL PF10241.9 KNZ80132.1 - 4.6 7.6 9.0 2.2 8.6 3.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein COG2 PF06148.11 KNZ80132.1 - 5.6 7.1 8.3 18 5.4 2.1 2.6 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 KASH_CCD PF14662.6 KNZ80132.1 - 8.3 6.2 15.3 12 5.7 5.8 2.9 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fungal_trans PF04082.18 KNZ80133.1 - 1.6e-20 73.3 0.9 4e-20 72.0 0.9 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ80133.1 - 2e-05 24.6 10.1 3.3e-05 23.9 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_efflux PF01545.21 KNZ80134.1 - 2e-39 135.4 15.9 2e-39 135.4 15.9 2.9 2 1 0 2 2 2 1 Cation efflux family Fungal_trans PF04082.18 KNZ80135.1 - 2e-05 23.8 0.1 7.3e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ80135.1 - 1.5 9.0 8.2 2.7 8.2 8.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PDCD2_C PF04194.13 KNZ80136.1 - 3.8e-42 144.3 1.3 7.4e-42 143.4 0.1 2.1 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PTRF_SDPR PF15237.6 KNZ80136.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 PTRF/SDPR family Hexokinase_2 PF03727.16 KNZ80137.1 - 3.7e-81 272.1 0.0 5e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KNZ80137.1 - 8.1e-68 228.2 0.0 1.1e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 KNZ80137.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Helitron_like_N PF14214.6 KNZ80138.1 - 2.2e-64 217.2 0.1 3.3e-64 216.6 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ80138.1 - 0.073 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) Pkinase PF00069.25 KNZ80139.1 - 1.6e-26 93.3 0.0 2e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80139.1 - 2.4e-09 36.9 0.0 3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ80139.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ80139.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KNZ80139.1 - 0.15 11.7 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 KNZ80144.1 - 1.4e-56 191.7 0.0 2.3e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ80144.1 - 1.5e-40 139.3 0.0 8e-40 136.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KNZ80144.1 - 3.4e-05 22.8 0.0 4.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 KNZ80144.1 - 0.0012 18.3 0.1 0.002 17.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Arm PF00514.23 KNZ80144.1 - 0.0039 17.2 5.7 2.3 8.4 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Haspin_kinase PF12330.8 KNZ80144.1 - 0.023 13.6 0.1 0.039 12.9 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KNZ80144.1 - 0.037 13.6 0.1 0.062 12.9 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 KNZ80144.1 - 0.054 13.4 0.1 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_5 PF14634.6 KNZ80145.1 - 0.0069 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain UBA2_C PF16195.5 KNZ80145.1 - 0.56 10.9 2.1 0.61 10.8 0.1 2.0 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus ATPgrasp_Ter PF15632.6 KNZ80146.1 - 0.16 11.7 0.0 0.6 9.9 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF1996 PF09362.10 KNZ80147.1 - 3e-76 256.5 0.8 4.7e-76 255.9 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Tub_N PF16322.5 KNZ80147.1 - 0.0013 19.2 0.1 1.2 9.6 0.0 2.3 1 1 0 2 2 2 1 Tubby N-terminal RGS PF00615.19 KNZ80148.1 - 6.1e-20 71.7 1.0 1.4e-19 70.5 1.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KNZ80148.1 - 1.2e-07 31.7 0.1 0.01 15.9 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RF-1 PF00472.20 KNZ80149.1 - 3.5e-22 78.5 1.3 4.7e-22 78.1 1.3 1.1 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 KNZ80149.1 - 0.0046 17.4 0.5 0.0077 16.7 0.5 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AP3D1 PF06375.11 KNZ80149.1 - 0.033 14.4 3.7 0.054 13.7 3.7 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Arrestin_N PF00339.29 KNZ80151.1 - 8.1e-06 25.9 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KNZ80151.1 - 0.018 15.5 0.1 6.8 7.2 0.0 3.5 4 0 0 4 4 4 0 Arrestin (or S-antigen), C-terminal domain MAP17 PF15807.5 KNZ80151.1 - 3 8.1 5.3 6.6 7.0 5.3 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ABC2_membrane PF01061.24 KNZ80152.1 - 3.9e-23 82.0 22.3 6e-23 81.4 22.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KNZ80152.1 - 0.00051 20.6 0.0 0.0081 16.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter COX6B PF02297.17 KNZ80154.1 - 6.7e-22 77.5 4.3 8.5e-22 77.2 4.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KNZ80154.1 - 0.013 15.8 1.2 0.034 14.5 1.1 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 FAD_binding_4 PF01565.23 KNZ80155.1 - 8.7e-21 74.1 0.7 2e-20 72.9 0.7 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 KNZ80155.1 - 0.00091 19.3 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.24 KNZ80156.1 - 6.9e-13 48.3 13.7 7.2e-12 44.9 13.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ80156.1 - 1.6e-11 43.8 27.0 1.1e-05 24.6 14.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.19 KNZ80156.1 - 9.6e-07 28.6 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CK_II_beta PF01214.18 KNZ80157.1 - 2e-79 265.7 0.0 2.4e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RabGAP-TBC PF00566.18 KNZ80158.1 - 1.7e-49 168.4 0.0 2.6e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lipase_3 PF01764.25 KNZ80159.1 - 2.8e-29 101.8 0.1 4.3e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 KNZ80159.1 - 0.00016 21.1 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ80159.1 - 0.0014 19.3 0.2 0.0017 19.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 KNZ80159.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 KNZ80159.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold ExoD PF06055.12 KNZ80159.1 - 0.037 13.4 0.1 0.59 9.5 0.1 2.2 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD PGAP1 PF07819.13 KNZ80159.1 - 0.075 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chromo PF00385.24 KNZ80161.1 - 7.9e-14 51.3 0.1 9.8e-14 51.0 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.6 KNZ80162.1 - 3.5e-05 24.3 0.0 0.00042 20.8 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80162.1 - 0.00024 21.7 0.0 0.0034 18.0 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.11 KNZ80162.1 - 0.088 12.6 0.1 0.66 9.7 0.0 2.1 2 1 0 2 2 2 0 Retroviral aspartyl protease Sdh_cyt PF01127.22 KNZ80164.1 - 6.4e-25 87.5 0.8 8.2e-25 87.2 0.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MINDY_DUB PF04424.13 KNZ80165.1 - 2.5e-28 98.4 0.0 1.2e-26 93.0 0.0 2.3 2 0 0 2 2 2 2 MINDY deubiquitinase RNase_P_Rpp14 PF01900.19 KNZ80166.1 - 2.7e-29 101.4 0.0 3.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF4139 PF13598.6 KNZ80167.1 - 4.2e-37 127.9 0.0 1.2e-36 126.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KNZ80167.1 - 2e-13 50.6 0.7 7.3e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF11 PF01345.18 KNZ80167.1 - 0.046 14.0 0.3 0.39 11.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF11 Nucleoporin_FG PF13634.6 KNZ80167.1 - 0.054 14.3 6.0 0.21 12.5 6.0 1.9 1 1 0 1 1 1 0 Nucleoporin FG repeat region FmdA_AmdA PF03069.15 KNZ80168.1 - 3.8e-156 519.6 0.0 4.7e-156 519.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family SET PF00856.28 KNZ80169.1 - 4.9e-13 49.8 0.0 1.5e-11 45.0 0.0 2.6 2 1 0 2 2 2 1 SET domain Ribosomal_S7 PF00177.21 KNZ80170.1 - 1.4e-26 92.9 0.1 1.6e-26 92.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e TPR_1 PF00515.28 KNZ80172.1 - 4.1e-19 67.5 1.3 3.8e-06 26.5 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ80172.1 - 1.8e-17 62.0 5.1 2.4e-06 27.2 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ80172.1 - 6.4e-10 39.0 6.6 0.00011 22.7 1.0 4.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ80172.1 - 1.4e-09 37.5 0.8 0.00018 21.1 0.7 2.4 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 KNZ80172.1 - 2e-09 37.9 3.2 2.4e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ80172.1 - 1.3e-08 34.4 1.4 0.034 14.3 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ80172.1 - 2.2e-07 31.3 2.8 5e-05 23.7 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ80172.1 - 5.3e-07 29.8 12.6 0.00047 20.4 1.9 4.1 4 1 2 6 6 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ80172.1 - 8.1e-06 26.1 3.9 0.034 14.8 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ80172.1 - 1.6e-05 24.6 4.6 0.017 15.1 0.0 4.4 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ80172.1 - 0.00012 21.4 1.2 0.00022 20.6 1.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ80172.1 - 0.0027 17.9 0.4 0.013 15.7 0.2 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 KNZ80172.1 - 0.11 12.5 1.0 42 4.3 0.1 3.3 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 KNZ80172.1 - 0.12 12.9 1.9 0.4 11.1 1.9 1.9 1 1 0 1 1 1 0 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 KNZ80172.1 - 0.15 11.5 0.1 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 SHNi-TPR TPR_10 PF13374.6 KNZ80172.1 - 0.56 10.1 11.0 6.4 6.8 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ80172.1 - 0.87 9.8 7.5 1.9 8.7 1.9 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.9 KNZ80172.1 - 7.4 6.1 15.9 1.4 8.5 11.4 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ricin_B_lectin PF00652.22 KNZ80173.1 - 7e-21 74.8 9.1 3.5e-15 56.4 5.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KNZ80173.1 - 8.7e-13 48.8 9.7 4e-07 30.7 0.8 3.7 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Crisp PF08562.10 KNZ80173.1 - 0.7 10.5 6.1 0.14 12.8 0.8 2.4 2 0 0 2 2 2 0 Crisp Aminotran_1_2 PF00155.21 KNZ80174.1 - 2.6e-36 125.6 0.0 3.8e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KNZ80174.1 - 1.3e-05 24.0 0.0 1.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KNZ80174.1 - 0.00043 19.7 0.0 0.00079 18.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KNZ80174.1 - 0.0024 17.2 0.1 0.0068 15.8 0.1 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KNZ80174.1 - 0.0027 16.7 0.0 0.0066 15.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KNZ80174.1 - 0.0084 14.9 0.0 0.012 14.3 0.0 1.3 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain SHMT PF00464.19 KNZ80174.1 - 0.018 13.7 0.0 0.03 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydroxymethyltransferase FAD_binding_3 PF01494.19 KNZ80175.1 - 1.3e-11 44.4 0.0 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.24 KNZ80175.1 - 1.7e-07 30.9 0.2 0.015 14.6 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ80175.1 - 1e-06 28.9 0.1 3.9e-06 27.0 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ80175.1 - 3.4e-06 26.9 0.6 0.0097 15.5 0.2 2.7 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ80175.1 - 3e-05 23.4 0.1 0.00011 21.6 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ80175.1 - 0.00016 20.9 0.0 0.00038 19.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KNZ80175.1 - 0.00069 19.0 0.0 0.045 13.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ80175.1 - 0.002 18.6 0.1 0.006 17.1 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KNZ80175.1 - 0.0025 17.2 0.1 0.0043 16.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KNZ80175.1 - 0.0092 14.7 0.0 0.019 13.7 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KNZ80175.1 - 0.017 14.2 0.0 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 KNZ80175.1 - 0.063 12.5 0.1 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 KNZ80175.1 - 0.14 11.2 0.0 0.28 10.2 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A E1-E2_ATPase PF00122.20 KNZ80176.1 - 2.3e-38 131.5 15.7 1.7e-30 105.9 0.1 3.7 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KNZ80176.1 - 4.7e-28 98.1 5.8 4.7e-28 98.1 5.8 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KNZ80176.1 - 3.6e-17 63.3 0.0 1.8e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ80176.1 - 2.7e-16 59.4 0.0 4.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KNZ80176.1 - 4.1e-15 55.2 0.3 4.1e-15 55.2 0.3 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KNZ80176.1 - 0.0043 16.8 0.2 0.02 14.6 0.3 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GPHR_N PF12537.8 KNZ80177.1 - 0.082 13.0 2.0 0.14 12.2 1.4 1.8 1 1 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF4418 PF14387.6 KNZ80177.1 - 1.1 9.4 7.7 0.33 11.1 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) PIG-P PF08510.12 KNZ80177.1 - 7.1 6.6 7.3 7.5 6.5 3.8 2.8 1 1 1 2 2 2 0 PIG-P Hydrophobin PF01185.18 KNZ80178.1 - 0.007 17.0 0.1 0.0093 16.6 0.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin TPP_enzyme_N PF02776.18 KNZ80181.1 - 5.7e-37 127.0 0.0 8e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNZ80181.1 - 3e-16 59.4 0.0 7.3e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNZ80181.1 - 9e-11 41.8 0.0 1.7e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4226 PF10774.9 KNZ80181.1 - 0.1 12.9 0.1 0.46 10.8 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4226) ADH_zinc_N PF00107.26 KNZ80182.1 - 6.9e-31 106.9 0.6 1.5e-30 105.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ80182.1 - 3.2e-28 97.8 2.6 6.5e-28 96.8 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KNZ80182.1 - 9.7e-05 23.4 0.0 0.00015 22.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KNZ80182.1 - 0.00062 19.1 0.2 0.001 18.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 KNZ80182.1 - 0.053 13.0 0.4 0.16 11.4 0.2 2.0 2 0 0 2 2 2 0 short chain dehydrogenase FAD_binding_3 PF01494.19 KNZ80184.1 - 5.7e-15 55.4 0.0 1.9e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ80184.1 - 7.4e-12 45.1 0.1 4.7e-07 29.3 0.0 1.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ80184.1 - 1e-11 45.0 1.4 1.4e-05 24.9 0.3 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KNZ80184.1 - 1.3e-08 34.6 0.1 0.00027 20.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KNZ80184.1 - 3.1e-07 30.5 0.8 1.2e-06 28.7 0.6 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KNZ80184.1 - 4.2e-06 27.2 0.0 0.00039 20.9 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ80184.1 - 1.2e-05 24.7 0.0 0.0063 15.8 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ80184.1 - 0.0001 21.1 0.1 0.0008 18.2 0.1 2.0 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KNZ80184.1 - 0.00014 21.1 0.2 0.00026 20.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KNZ80184.1 - 0.00015 21.3 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KNZ80184.1 - 0.00031 19.9 0.1 0.00049 19.3 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A PTCRA PF15028.6 KNZ80184.1 - 0.019 14.6 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Lycopene_cycl PF05834.12 KNZ80184.1 - 0.024 13.7 0.0 2 7.4 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KNZ80184.1 - 0.025 13.4 0.1 0.096 11.5 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KNZ80184.1 - 0.032 13.5 0.1 0.061 12.6 0.0 1.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KNZ80184.1 - 0.052 12.8 0.4 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Thi4 family MBOAT PF03062.19 KNZ80185.1 - 4.2e-48 164.5 26.7 7.2e-48 163.7 26.7 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Hydrophobin PF01185.18 KNZ80187.1 - 5.3e-18 65.4 9.6 6.6e-18 65.1 9.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF281 PF03436.13 KNZ80187.1 - 0.11 12.9 1.5 0.11 12.9 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Toxin_12 PF07740.12 KNZ80187.1 - 0.22 12.3 11.2 0.21 12.3 3.0 2.3 2 0 0 2 2 2 0 Ion channel inhibitory toxin zf-RVT PF13966.6 KNZ80188.1 - 9.3e-05 23.1 1.3 0.00028 21.5 0.1 2.1 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KNZ80188.1 - 0.0047 17.1 0.2 0.0086 16.3 0.2 1.5 1 0 0 1 1 1 1 RNase H Zn_Tnp_IS1595 PF12760.7 KNZ80188.1 - 0.05 13.6 0.5 0.05 13.6 0.5 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Cupin_1 PF00190.22 KNZ80190.1 - 7.7e-42 142.5 0.5 3.9e-20 72.0 0.1 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KNZ80190.1 - 1e-29 102.0 1.1 3.3e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KNZ80190.1 - 4.9e-10 38.9 0.3 0.00024 20.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KNZ80190.1 - 1.5e-07 31.4 0.4 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 KNZ80190.1 - 0.0001 22.2 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 KNZ80190.1 - 0.00041 20.6 0.5 0.27 11.4 0.0 2.1 2 0 0 2 2 2 2 ARD/ARD' family 3-HAO PF06052.12 KNZ80190.1 - 0.0047 16.6 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase DcpS_C PF11969.8 KNZ80191.1 - 5.6e-07 30.0 0.4 6.6e-07 29.8 0.4 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KNZ80191.1 - 0.15 12.8 1.3 0.23 12.2 1.3 1.3 1 0 0 1 1 1 0 HIT domain UCH PF00443.29 KNZ80192.1 - 4.5e-45 154.2 0.0 7.6e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ80192.1 - 6.1e-18 65.5 9.2 1.9e-17 63.9 3.5 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KNZ80192.1 - 6.4e-05 23.2 13.3 6.4e-05 23.2 13.3 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Thg1 PF04446.12 KNZ80193.1 - 9.8e-50 167.8 0.1 1.7e-49 167.0 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KNZ80193.1 - 3e-45 153.3 0.1 4.2e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain I_LWEQ PF01608.17 KNZ80194.1 - 0.23 11.7 0.9 0.39 11.0 0.9 1.3 1 0 0 1 1 1 0 I/LWEQ domain CDC45 PF02724.14 KNZ80194.1 - 0.38 9.0 3.5 0.41 8.9 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein UPF0560 PF10577.9 KNZ80194.1 - 1.6 7.1 5.5 2 6.8 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Forkhead PF00250.18 KNZ80195.1 - 7.9e-21 74.1 0.1 2.8e-20 72.4 0.1 1.8 1 1 0 1 1 1 1 Forkhead domain DNA_pol_viral_N PF00242.17 KNZ80196.1 - 1.6 8.2 7.8 3.2 7.2 7.8 1.4 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MFS_1 PF07690.16 KNZ80197.1 - 6.5e-21 74.6 21.9 6.5e-21 74.6 21.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KNZ80197.1 - 9.3e-06 24.7 7.4 0.00036 19.5 2.5 2.1 1 1 1 2 2 2 2 MFS_1 like family COesterase PF00135.28 KNZ80198.1 - 6.4e-81 272.8 0.0 1.5e-80 271.6 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ80198.1 - 6.2e-12 45.8 0.3 3.7e-11 43.3 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KNZ80198.1 - 0.00014 21.6 0.1 0.00045 19.9 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KNZ80198.1 - 0.014 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KNZ80198.1 - 0.17 10.7 0.1 0.54 9.1 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase Asp_protease_2 PF13650.6 KNZ80200.1 - 0.0044 17.6 0.0 0.0056 17.3 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 KNZ80200.1 - 0.038 13.7 0.0 0.082 12.7 0.0 1.5 1 1 1 2 2 2 0 Retroviral aspartyl protease Senescence PF06911.12 KNZ80202.1 - 1.1e-49 169.2 0.6 2.5e-49 168.1 0.6 1.6 1 1 0 1 1 1 1 Senescence-associated protein Nse4_C PF08743.10 KNZ80206.1 - 2.7e-30 104.4 0.1 2.7e-30 104.4 0.1 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KNZ80206.1 - 1.5e-19 69.9 1.4 3.3e-19 68.7 1.4 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Hat1_N PF10394.9 KNZ80207.1 - 8.2e-51 172.4 0.1 1.9e-50 171.3 0.1 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 KNZ80207.1 - 8.3e-07 29.3 0.0 2.3e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 KNZ80207.1 - 0.00098 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_10 PF13673.7 KNZ80207.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ80207.1 - 0.038 14.4 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNZ80207.1 - 0.074 13.7 0.1 0.21 12.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DNApol_Exo PF18136.1 KNZ80208.1 - 3.2e-102 341.5 0.1 4.9e-102 340.8 0.1 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KNZ80208.1 - 1.9e-49 168.7 0.0 3.5e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 KNZ80208.1 - 0.028 14.1 0.1 0.28 10.9 0.1 2.4 1 1 0 1 1 1 0 3'-5' exonuclease CoA_trans PF01144.23 KNZ80209.1 - 1.9e-102 341.2 3.0 5.5e-61 205.7 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 KNZ80209.1 - 9.5e-05 22.4 0.1 0.00021 21.2 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 KNZ80209.1 - 0.011 15.7 0.7 0.46 10.4 0.0 2.9 4 0 0 4 4 4 0 Acetyl-CoA hydrolase/transferase N-terminal domain Pkinase_fungal PF17667.1 KNZ80211.1 - 8.8e-57 192.7 0.2 8.8e-57 192.7 0.2 2.5 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KNZ80211.1 - 4.4e-06 26.8 0.0 3.5e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ80211.1 - 2.9e-05 23.6 0.1 5.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KNZ80211.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.17 KNZ80211.1 - 0.02 14.2 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Chromo PF00385.24 KNZ80212.1 - 1.3e-15 57.0 0.0 1.6e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Aldo_ket_red PF00248.21 KNZ80213.1 - 1.1e-27 97.0 0.0 1.6e-24 86.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Plasmodium_Vir PF05795.11 KNZ80214.1 - 1.3 8.4 4.9 2 7.8 4.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.9 KNZ80214.1 - 6.9 5.1 11.3 9.2 4.7 11.3 1.1 1 0 0 1 1 1 0 Macoilin family MDD_C PF18376.1 KNZ80215.1 - 9.8e-70 234.1 0.0 1.3e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KNZ80215.1 - 2.9e-06 27.4 5.6 6.5e-06 26.3 5.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Exo_endo_phos PF03372.23 KNZ80216.1 - 7.3e-22 78.0 0.0 8.1e-21 74.6 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 KNZ80216.1 - 2.8e-16 59.0 18.3 6.1e-09 35.5 0.1 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 KNZ80216.1 - 5.7e-13 48.8 0.6 1.6e-05 25.1 1.2 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KNZ80216.1 - 0.014 15.8 1.0 2.4 9.0 0.1 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KNZ80216.1 - 0.069 13.2 1.4 1.7 8.9 0.6 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Muskelin_N PF06588.11 KNZ80217.1 - 2.3e-46 158.2 0.0 3.8e-46 157.5 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_4 PF13418.6 KNZ80217.1 - 1.2e-23 82.9 2.7 5.2e-06 26.4 0.0 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 KNZ80217.1 - 6e-22 77.2 0.8 5.9e-10 38.9 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 KNZ80217.1 - 1.2e-19 70.1 14.5 2.8e-09 37.0 0.0 7.8 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ80217.1 - 2.2e-13 50.0 3.0 9.9e-05 22.5 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 KNZ80217.1 - 1e-12 47.4 8.7 9.6e-08 31.5 0.1 5.2 5 0 0 5 5 5 2 Kelch motif F5_F8_type_C PF00754.25 KNZ80217.1 - 4.8e-07 29.9 0.5 3e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 F5/8 type C domain Sad1_UNC PF07738.13 KNZ80217.1 - 0.032 14.2 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal ANAPC2 PF08672.11 KNZ80218.1 - 0.0046 17.4 0.1 1.7 9.2 0.1 2.2 1 1 1 2 2 2 2 Anaphase promoting complex (APC) subunit 2 Prefoldin_2 PF01920.20 KNZ80219.1 - 1e-23 83.3 6.0 1.3e-23 82.9 6.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 KNZ80219.1 - 0.001 19.0 6.3 0.14 12.1 1.5 2.2 1 1 1 2 2 2 2 Prefoldin subunit ZapB PF06005.12 KNZ80219.1 - 0.0023 18.3 4.4 0.0048 17.3 4.4 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Spc24 PF08286.11 KNZ80219.1 - 0.006 16.8 7.7 0.49 10.7 0.1 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 FliD_C PF07195.12 KNZ80219.1 - 0.0063 16.0 0.9 0.19 11.1 0.0 2.0 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Seryl_tRNA_N PF02403.22 KNZ80219.1 - 0.0087 16.3 6.4 0.67 10.2 0.1 2.2 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain HMMR_N PF15905.5 KNZ80219.1 - 0.015 14.8 7.1 0.018 14.5 7.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF465 PF04325.13 KNZ80219.1 - 0.017 15.2 6.6 0.063 13.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF465) UPF0449 PF15136.6 KNZ80219.1 - 0.018 15.5 3.9 0.41 11.2 2.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 MIF4G_like_2 PF09090.11 KNZ80219.1 - 0.026 14.0 0.3 0.028 13.9 0.3 1.2 1 0 0 1 1 1 0 MIF4G like DivIC PF04977.15 KNZ80219.1 - 0.03 14.1 8.8 0.17 11.7 3.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Katanin_con80 PF13925.6 KNZ80219.1 - 0.035 14.2 0.2 0.058 13.4 0.2 1.3 1 0 0 1 1 1 0 con80 domain of Katanin Vps51 PF08700.11 KNZ80219.1 - 0.045 13.8 1.5 2 8.6 0.3 2.4 2 0 0 2 2 2 0 Vps51/Vps67 DASH_Dam1 PF08653.10 KNZ80219.1 - 0.052 13.3 4.5 0.12 12.2 1.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 V_ATPase_I PF01496.19 KNZ80219.1 - 0.082 10.8 2.2 0.095 10.6 2.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4988 PF16378.5 KNZ80219.1 - 0.083 12.6 3.1 6.3 6.4 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function PCRF PF03462.18 KNZ80219.1 - 0.12 12.3 5.1 0.15 11.9 5.1 1.2 1 0 0 1 1 1 0 PCRF domain DUF1664 PF07889.12 KNZ80219.1 - 0.13 12.3 0.9 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 KNZ80219.1 - 0.14 12.2 10.6 2.7 8.0 5.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FliD_N PF02465.18 KNZ80219.1 - 0.15 12.8 1.8 2.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FlxA PF14282.6 KNZ80219.1 - 0.24 11.4 7.1 1.6 8.8 1.3 2.2 2 0 0 2 2 2 0 FlxA-like protein Spc7 PF08317.11 KNZ80219.1 - 0.25 10.2 8.6 0.34 9.8 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 KNZ80219.1 - 0.25 11.7 3.3 2.6 8.5 0.7 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 KNZ80219.1 - 0.3 11.5 4.5 1.1 9.7 2.1 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 KNZ80219.1 - 0.39 11.4 6.0 10 6.8 2.7 2.2 1 1 0 2 2 2 0 Initiation control protein YabA Helo_like_N PF17111.5 KNZ80219.1 - 0.55 9.6 7.1 0.87 8.9 3.0 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins APG6_N PF17675.1 KNZ80219.1 - 0.74 10.3 15.2 6.6 7.3 0.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DASH_Dad3 PF08656.10 KNZ80219.1 - 0.89 9.7 5.1 1.8 8.7 0.9 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF724 PF05266.14 KNZ80219.1 - 1.1 9.0 7.6 8.3 6.2 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FapA PF03961.13 KNZ80219.1 - 1.6 7.2 4.3 2 7.0 3.0 1.6 1 1 1 2 2 2 0 Flagellar Assembly Protein A M PF02370.16 KNZ80219.1 - 2.2 9.1 10.3 5.9 7.8 5.8 2.9 2 0 0 2 2 2 0 M protein repeat Ax_dynein_light PF10211.9 KNZ80219.1 - 2.2 8.2 8.9 14 5.6 0.2 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain Exonuc_VII_L PF02601.15 KNZ80219.1 - 2.7 7.5 5.3 4.5 6.7 5.3 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit EMP24_GP25L PF01105.24 KNZ80219.1 - 5.2 7.0 6.7 2.4 8.1 2.5 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD KfrA_N PF11740.8 KNZ80219.1 - 5.3 7.7 7.7 11 6.8 0.1 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Pyridoxal_deC PF00282.19 KNZ80220.1 - 9.2e-11 41.1 0.0 1.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KNZ80220.1 - 3.3e-05 23.0 0.0 0.0002 20.5 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KNZ80220.1 - 0.0043 16.4 0.1 0.0069 15.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_N PF00339.29 KNZ80221.1 - 3.8e-08 33.5 0.0 9.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KNZ80221.1 - 8.2e-07 29.5 1.0 0.0001 22.8 0.6 3.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 KNZ80221.1 - 0.0015 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like DUF5427 PF10310.9 KNZ80221.1 - 4.4 6.2 5.0 6.5 5.6 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Acetyltransf_7 PF13508.7 KNZ80222.1 - 0.00015 22.1 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_3 PF13606.6 KNZ80222.1 - 0.00087 19.6 0.0 0.01 16.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 KNZ80222.1 - 0.004 17.7 0.0 0.018 15.6 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 KNZ80222.1 - 0.0044 17.4 0.0 0.097 13.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 KNZ80222.1 - 0.008 16.7 0.0 0.037 14.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ80222.1 - 0.012 15.9 0.1 0.041 14.2 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) peroxidase PF00141.23 KNZ80223.1 - 1.7e-46 158.7 0.0 2.8e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase zf-LYAR PF08790.11 KNZ80225.1 - 3.7e-13 49.1 3.6 6.6e-13 48.3 3.6 1.4 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger Autophagy_N PF03986.13 KNZ80226.1 - 9.8e-43 145.4 0.2 1.9e-42 144.5 0.0 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 KNZ80226.1 - 4e-17 62.5 0.6 8.1e-17 61.6 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 KNZ80226.1 - 9.8e-13 47.4 2.9 2.4e-12 46.1 2.9 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal UTP25 PF06862.12 KNZ80227.1 - 1.3e-151 505.6 0.0 1.7e-151 505.3 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Topoisom_bac PF01131.20 KNZ80228.1 - 6.1e-104 348.3 0.0 7.3e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 KNZ80228.1 - 1.7e-20 73.1 0.0 6.8e-19 68.0 0.0 2.7 3 0 0 3 3 3 1 Toprim domain MMS1_N PF10433.9 KNZ80230.1 - 1.8e-158 528.2 0.0 2.4e-158 527.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KNZ80230.1 - 1.2e-91 307.4 0.0 1.2e-90 304.2 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region OsmC PF02566.19 KNZ80231.1 - 1.6e-12 47.8 0.0 2.2e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein CHD5 PF04420.14 KNZ80232.1 - 1.8e-50 170.9 1.9 2.1e-50 170.7 1.9 1.1 1 0 0 1 1 1 1 CHD5-like protein Lipoprotein_6 PF01441.19 KNZ80232.1 - 0.0085 16.1 0.3 0.011 15.7 0.3 1.2 1 0 0 1 1 1 1 Lipoprotein Malate_synthase PF01274.22 KNZ80233.1 - 1e-197 657.6 0.0 1.3e-197 657.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase FKBP_C PF00254.28 KNZ80234.1 - 1.1e-33 115.4 0.0 1.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nkap_C PF06047.11 KNZ80235.1 - 1.7e-41 140.4 7.0 1.7e-41 140.4 7.0 2.7 3 0 0 3 3 3 1 NF-kappa-B-activating protein C-terminal domain Gln-synt_C PF00120.24 KNZ80236.1 - 9.7e-64 215.5 0.0 1.3e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Integrase_H2C2 PF17921.1 KNZ80237.1 - 6e-10 39.1 3.1 6e-10 39.1 3.1 2.2 2 0 0 2 2 2 1 Integrase zinc binding domain Fer4_22 PF17179.4 KNZ80237.1 - 0.07 14.0 2.2 0.15 12.9 2.2 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Gln-synt_C PF00120.24 KNZ80241.1 - 8.4e-65 219.0 0.0 1.1e-64 218.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Fungal_trans PF04082.18 KNZ80242.1 - 1.6e-27 96.2 0.2 4.7e-27 94.7 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 KNZ80242.1 - 0.0014 18.8 0.5 0.0039 17.3 0.5 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain gag-asp_proteas PF13975.6 KNZ80243.1 - 5e-07 30.2 0.0 7.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80243.1 - 1e-05 26.1 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ80243.1 - 0.0014 18.4 0.3 0.0048 16.7 0.2 1.8 1 1 1 2 2 2 1 Aspartyl protease WSC PF01822.19 KNZ80247.1 - 1.6e-35 121.1 19.9 5.2e-18 65.0 7.9 2.3 2 0 0 2 2 2 2 WSC domain Vps53_N PF04100.12 KNZ80248.1 - 4e-88 295.9 1.5 8.2e-88 294.9 1.5 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 KNZ80248.1 - 1.4e-07 31.1 1.0 2.8e-07 30.1 1.0 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex VPS53_C PF16854.5 KNZ80248.1 - 3.8e-05 23.7 5.7 0.00018 21.5 0.0 3.8 3 1 1 4 4 4 1 Vacuolar protein sorting-associated protein 53 C-terminus RINT1_TIP1 PF04437.13 KNZ80248.1 - 0.00012 21.1 1.5 0.00012 21.1 1.5 2.4 2 2 0 2 2 2 1 RINT-1 / TIP-1 family DUF2451 PF10474.9 KNZ80248.1 - 0.0084 15.9 0.5 0.0084 15.9 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Herpes_UL42 PF02282.16 KNZ80248.1 - 0.0094 15.8 0.2 0.13 12.1 0.1 2.3 2 0 0 2 2 2 1 DNA polymerase processivity factor (UL42) Homoserine_dh PF00742.19 KNZ80248.1 - 0.097 12.6 0.9 0.88 9.5 0.1 2.3 2 0 0 2 2 2 0 Homoserine dehydrogenase FlxA PF14282.6 KNZ80248.1 - 0.22 11.5 8.0 0.53 10.3 6.6 2.2 2 0 0 2 2 2 0 FlxA-like protein T3SS_needle_E PF08988.10 KNZ80248.1 - 0.22 11.7 5.7 6.2 7.1 2.3 3.7 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Mei5 PF10376.9 KNZ80248.1 - 0.4 10.5 7.3 0.055 13.3 1.6 2.2 2 0 0 2 2 2 0 Double-strand recombination repair protein DUF1664 PF07889.12 KNZ80248.1 - 1 9.4 12.4 0.043 13.9 4.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) GIT_CC PF16559.5 KNZ80248.1 - 1.5 8.7 7.0 0.19 11.6 0.9 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CorA PF01544.18 KNZ80248.1 - 5.1 6.3 10.0 3.1 7.0 6.0 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Yippee-Mis18 PF03226.14 KNZ80249.1 - 1.2e-11 44.8 0.2 2.4e-11 43.8 0.2 1.5 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Rpr2 PF04032.16 KNZ80250.1 - 2.7e-23 82.1 0.7 5.8e-23 81.0 0.7 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Hormone_6 PF00236.18 KNZ80250.1 - 0.042 13.8 0.9 0.099 12.6 0.4 1.9 1 1 0 1 1 1 0 Glycoprotein hormone zf-RING_7 PF02591.15 KNZ80250.1 - 0.15 12.3 1.2 1.8 8.8 0.9 2.8 2 1 0 2 2 2 0 C4-type zinc ribbon domain MRP-L27 PF09809.9 KNZ80251.1 - 4.5e-08 32.9 0.2 8e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HCO3_cotransp PF00955.21 KNZ80252.1 - 4.1e-59 200.8 18.6 1.4e-24 86.8 2.0 3.1 2 1 1 3 3 3 3 HCO3- transporter family Ctr PF04145.15 KNZ80253.1 - 6.1e-36 124.3 0.0 7.1e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Proteasome PF00227.26 KNZ80254.1 - 2.1e-53 180.6 0.2 1.4e-52 177.9 0.1 2.5 3 0 0 3 3 3 1 Proteasome subunit Ank_2 PF12796.7 KNZ80254.1 - 4.8e-05 23.9 0.0 0.00018 22.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ80254.1 - 0.0003 21.0 0.0 0.048 14.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KNZ80254.1 - 0.0015 18.8 0.0 0.019 15.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ80254.1 - 0.0022 18.5 0.0 0.0091 16.6 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Acetyltransf_7 PF13508.7 KNZ80254.1 - 0.0072 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank PF00023.30 KNZ80254.1 - 0.021 15.2 0.0 0.92 10.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Bac_rhamnosid_N PF08531.10 KNZ80255.1 - 8.1e-06 25.8 1.0 0.0048 16.7 0.0 4.0 3 2 0 3 3 3 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.18 KNZ80255.1 - 0.016 15.1 0.0 0.58 10.0 0.0 2.5 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain OSCP PF00213.18 KNZ80256.1 - 0.057 13.5 0.1 0.057 13.5 0.1 1.0 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit CHZ PF09649.10 KNZ80258.1 - 2e-12 46.3 0.7 2e-12 46.3 0.7 2.2 2 1 0 2 2 2 1 Histone chaperone domain CHZ CDC45 PF02724.14 KNZ80258.1 - 0.53 8.5 3.9 0.66 8.2 3.9 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 KNZ80258.1 - 0.94 9.7 15.4 0.082 13.1 9.1 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.12 KNZ80258.1 - 2 7.6 15.4 0.12 11.7 8.2 2.1 2 0 0 2 2 2 0 NOA36 protein FAM176 PF14851.6 KNZ80258.1 - 7.8 6.2 14.2 0.95 9.1 9.6 1.8 1 1 1 2 2 2 0 FAM176 family Nop14 PF04147.12 KNZ80258.1 - 9 4.4 16.3 12 3.9 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_4 PF13637.6 KNZ80259.1 - 0.0002 21.8 0.1 0.00078 20.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ80259.1 - 0.0011 19.5 0.1 0.0044 17.6 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ80259.1 - 0.016 15.7 0.0 7.1 7.5 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Acetyltransf_7 PF13508.7 KNZ80259.1 - 0.019 15.4 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ80259.1 - 0.024 14.9 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ank_5 PF13857.6 KNZ80259.1 - 0.057 13.8 0.1 0.29 11.5 0.1 2.2 2 1 0 2 2 2 0 Ankyrin repeats (many copies) GKAP PF03359.13 KNZ80261.1 - 7.3 6.1 10.3 0.096 12.2 1.8 1.8 2 0 0 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein bZIP_2 PF07716.15 KNZ80262.1 - 1.7e-09 37.6 14.5 2.8e-09 36.9 14.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KNZ80262.1 - 9e-09 35.3 9.7 1.3e-08 34.8 9.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor HAP1_N PF04849.13 KNZ80262.1 - 0.028 13.6 0.7 0.043 13.0 0.7 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_Maf PF03131.17 KNZ80262.1 - 0.028 14.9 6.6 0.028 14.9 6.6 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor TSC22 PF01166.18 KNZ80262.1 - 0.045 14.1 0.1 0.085 13.2 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family F-box-like PF12937.7 KNZ80263.1 - 0.00055 19.8 0.2 0.0017 18.2 0.2 1.9 1 0 0 1 1 1 1 F-box-like zf-RVT PF13966.6 KNZ80265.1 - 8.4e-06 26.4 1.1 2e-05 25.2 0.3 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KNZ80265.1 - 2.2e-05 24.7 0.0 5.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 RNase H Collagen PF01391.18 KNZ80266.1 - 0.0014 18.3 22.1 0.0014 18.3 22.1 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Glyco_hydro_63 PF03200.16 KNZ80267.1 - 4e-07 29.2 14.3 6.2e-07 28.5 1.2 4.4 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain RhoGAP PF00620.27 KNZ80268.1 - 8.2e-30 103.6 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Adeno_100 PF02438.16 KNZ80268.1 - 0.025 12.8 0.0 0.038 12.2 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein Mito_carr PF00153.27 KNZ80269.1 - 3.7e-70 231.9 12.0 7.6e-27 93.1 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KNZ80269.1 - 0.00071 18.8 1.2 0.24 10.5 0.0 3.1 1 1 1 3 3 3 2 Gammaproteobacterial serine protease CMD PF02627.20 KNZ80270.1 - 1.6e-13 50.5 0.0 3.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF3761 PF12587.8 KNZ80270.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3761) NAD_binding_11 PF14833.6 KNZ80271.1 - 7e-26 90.9 0.0 1.3e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 KNZ80271.1 - 9.5e-26 90.9 0.0 1.3e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GCP_C_terminal PF04130.13 KNZ80272.1 - 1.3e-57 195.6 0.1 2.5e-57 194.7 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KNZ80272.1 - 8.7e-05 22.3 0.0 0.00017 21.3 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF2367 PF10164.9 KNZ80273.1 - 1.1e-09 38.7 0.4 1.1e-09 38.7 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Methyltransf_25 PF13649.6 KNZ80274.1 - 6.2e-09 36.5 0.8 6e-07 30.1 0.3 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ80274.1 - 1.2e-07 31.7 0.5 4.2e-07 29.9 0.4 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KNZ80274.1 - 4.9e-07 29.4 1.4 2.4e-06 27.2 1.4 2.0 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KNZ80274.1 - 2.3e-06 28.1 0.2 8.7e-05 23.1 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ80274.1 - 3.4e-05 23.8 0.0 0.00019 21.3 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KNZ80274.1 - 0.00033 20.0 0.1 0.00058 19.2 0.1 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KNZ80274.1 - 0.00038 19.5 0.1 0.00089 18.3 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 KNZ80274.1 - 0.0012 18.5 0.3 0.0027 17.3 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KNZ80274.1 - 0.0036 18.0 0.1 0.0091 16.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KNZ80274.1 - 0.018 15.1 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KNZ80274.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KNZ80274.1 - 0.042 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 KNZ80274.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase FSIP2 PF15783.5 KNZ80274.1 - 0.13 10.2 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 Methyltransf_2 PF00891.18 KNZ80274.1 - 0.14 11.5 0.1 1.2 8.3 0.1 2.2 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 KNZ80274.1 - 0.15 12.0 0.1 1.4 8.8 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 KNZ80274.1 - 0.19 11.1 2.2 0.58 9.5 0.7 2.6 2 1 0 2 2 2 0 Tellurite resistance protein TehB Glyco_hydro_28 PF00295.17 KNZ80275.1 - 1.7e-60 204.8 12.8 2e-60 204.6 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KNZ80275.1 - 1.5e-07 31.4 16.2 1.5e-07 31.4 16.2 2.5 1 1 1 2 2 2 1 Right handed beta helix region DUF1565 PF07602.11 KNZ80275.1 - 0.03 13.7 11.9 0.0075 15.6 7.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) PH_10 PF15411.6 KNZ80276.1 - 5.5e-36 123.5 0.0 1.1e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 KNZ80276.1 - 8.9e-36 123.8 3.5 1.5e-35 123.1 3.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 KNZ80276.1 - 1.2e-16 60.4 0.0 2.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.11 KNZ80276.1 - 1.3e-11 44.6 0.0 2.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PARM PF17061.5 KNZ80276.1 - 0.033 14.4 0.2 0.033 14.4 0.2 2.2 2 0 0 2 2 2 0 PARM She9_MDM33 PF05546.11 KNZ80276.1 - 0.15 11.8 1.7 0.22 11.3 0.2 1.8 2 0 0 2 2 2 0 She9 / Mdm33 family BRCT_2 PF16589.5 KNZ80277.1 - 1.2e-07 32.0 0.0 4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KNZ80277.1 - 0.81 10.3 7.0 18 6.0 2.6 3.4 2 1 1 3 3 3 0 Rap1, DNA-binding PhyH PF05721.13 KNZ80278.1 - 7.3e-47 160.3 0.0 8.9e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) LRR_4 PF12799.7 KNZ80279.1 - 0.071 13.6 2.1 14 6.3 0.0 4.6 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) MitMem_reg PF13012.6 KNZ80279.1 - 0.073 13.5 0.1 0.62 10.5 0.1 2.1 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function UvrD_C_2 PF13538.6 KNZ80281.1 - 0.0067 16.2 0.0 0.0095 15.7 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 KNZ80281.1 - 0.13 10.2 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 Helicase Sugar_tr PF00083.24 KNZ80282.1 - 3.8e-91 306.2 18.0 7.7e-91 305.2 18.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ80282.1 - 1.8e-23 83.1 28.2 5.3e-21 74.9 12.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5069 PF16798.5 KNZ80283.1 - 9.2 6.5 10.5 5.5 7.2 1.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) DnaJ_CXXCXGXG PF00684.19 KNZ80284.1 - 2.8 8.4 8.9 0.43 11.0 1.3 2.8 2 1 0 2 2 2 0 DnaJ central domain DZR PF12773.7 KNZ80284.1 - 6.1 7.0 12.3 0.12 12.5 5.1 1.9 2 0 0 2 2 2 0 Double zinc ribbon Pro_isomerase PF00160.21 KNZ80285.1 - 2e-46 158.1 0.4 2.3e-46 158.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD gag_pre-integrs PF13976.6 KNZ80287.1 - 6.1e-09 35.6 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 KNZ80287.1 - 0.02 15.1 0.0 0.055 13.7 0.0 1.7 2 0 0 2 2 2 0 Integrase core domain DUF3808 PF10300.9 KNZ80288.1 - 1.8e-54 185.3 0.0 1.1e-42 146.4 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_16 PF13432.6 KNZ80288.1 - 0.021 15.5 1.2 11 6.8 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ80288.1 - 0.051 13.7 5.6 0.71 10.1 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Cag12 PF13117.6 KNZ80288.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 Cu-oxidase PF00394.22 KNZ80289.1 - 2.2e-42 144.9 0.0 1.2e-40 139.3 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ80289.1 - 1.6e-35 121.7 0.2 6.8e-34 116.4 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ80289.1 - 1.5e-34 118.6 2.9 7.5e-31 106.7 0.0 2.7 2 1 0 2 2 2 2 Multicopper oxidase Dynamin_M PF01031.20 KNZ80290.1 - 5e-31 108.0 0.0 8.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KNZ80290.1 - 3.2e-25 89.1 0.0 9.4e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 KNZ80290.1 - 7.8e-11 42.0 2.2 1.1e-10 41.5 0.0 2.5 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KNZ80290.1 - 0.00017 21.6 0.2 0.0029 17.7 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KNZ80290.1 - 0.022 15.2 0.5 0.31 11.4 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_29 PF13555.6 KNZ80290.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med22 PF06179.12 KNZ80291.1 - 0.071 13.3 0.7 0.15 12.3 0.7 1.5 1 1 0 1 1 1 0 Surfeit locus protein 5 subunit 22 of Mediator complex DUF1479 PF07350.12 KNZ80292.1 - 1e-48 166.1 0.5 1.4e-45 155.8 0.1 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) Peptidase_M48 PF01435.18 KNZ80293.1 - 4.6e-34 117.9 0.2 1e-33 116.8 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M10 PF00413.24 KNZ80293.1 - 0.051 13.4 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin DUF2268 PF10026.9 KNZ80293.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) RNA_pol_Rpb2_45 PF10385.9 KNZ80295.1 - 0.052 13.8 0.4 0.095 13.0 0.4 1.5 1 0 0 1 1 1 0 RNA polymerase beta subunit external 1 domain POT1PC PF16686.5 KNZ80296.1 - 0.16 11.8 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Retrotran_gag_2 PF14223.6 KNZ80298.1 - 5.9e-14 51.9 2.2 8.9e-14 51.3 2.2 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 KNZ80298.1 - 0.044 13.6 1.4 5.3 6.9 0.2 2.9 2 1 1 3 3 3 0 gag-polypeptide of LTR copia-type PRKG1_interact PF15898.5 KNZ80298.1 - 0.079 13.9 0.5 0.2 12.6 0.1 1.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain RRF_GI PF12614.8 KNZ80298.1 - 0.56 10.4 3.0 4.6 7.4 3.0 2.3 1 1 0 1 1 1 0 Ribosome recycling factor LamB_YcsF PF03746.16 KNZ80299.1 - 8.2e-72 241.7 0.0 9.2e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AAA PF00004.29 KNZ80300.1 - 1.1e-43 148.8 0.0 2.1e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ80300.1 - 1.5e-11 43.9 0.1 3.3e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KNZ80300.1 - 3.2e-08 33.9 0.0 6.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KNZ80300.1 - 2.2e-06 27.7 0.0 8.4e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ80300.1 - 9.8e-06 26.0 0.0 0.0001 22.7 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KNZ80300.1 - 2.2e-05 24.7 0.1 0.0063 16.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KNZ80300.1 - 6e-05 22.8 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_ID_OB PF16450.5 KNZ80300.1 - 0.00029 20.7 1.1 0.0029 17.5 1.1 2.4 1 1 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_18 PF13238.6 KNZ80300.1 - 0.00055 20.5 0.4 0.021 15.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 KNZ80300.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KNZ80300.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KNZ80300.1 - 0.0023 17.7 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 KNZ80300.1 - 0.0052 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KNZ80300.1 - 0.0086 15.5 0.1 0.021 14.2 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KNZ80300.1 - 0.0093 16.2 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 KNZ80300.1 - 0.0096 15.4 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 KNZ80300.1 - 0.013 15.6 0.0 0.059 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KNZ80300.1 - 0.015 15.0 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KNZ80300.1 - 0.016 15.2 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 KNZ80300.1 - 0.016 14.6 0.0 0.036 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.26 KNZ80300.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.1 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KNZ80300.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KNZ80300.1 - 0.032 13.4 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_13 PF13166.6 KNZ80300.1 - 0.037 12.7 0.2 1.6 7.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KNZ80300.1 - 0.044 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 KNZ80300.1 - 0.063 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 KNZ80300.1 - 0.065 12.8 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KNZ80300.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DivIC PF04977.15 KNZ80300.1 - 0.11 12.3 0.3 0.35 10.7 0.3 1.9 1 0 0 1 1 1 0 Septum formation initiator AAA_19 PF13245.6 KNZ80300.1 - 0.13 12.6 0.2 0.64 10.3 0.1 2.2 3 0 0 3 3 1 0 AAA domain AAA_11 PF13086.6 KNZ80300.1 - 0.14 11.9 0.1 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF5406 PF17400.2 KNZ80300.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5406) PIN_4 PF13638.6 KNZ80301.1 - 5.3e-07 30.0 0.1 1.4e-06 28.6 0.1 1.8 1 1 0 1 1 1 1 PIN domain DUF1778 PF08681.11 KNZ80302.1 - 0.098 12.6 3.9 0.21 11.5 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) Redoxin PF08534.10 KNZ80305.1 - 1.3e-27 96.3 0.1 1.5e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KNZ80305.1 - 6.6e-10 39.0 0.0 7.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1454 PF07305.12 KNZ80305.1 - 0.052 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) TPP_enzyme_N PF02776.18 KNZ80306.1 - 2.2e-32 112.0 0.0 4.2e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KNZ80306.1 - 3.1e-13 49.8 0.0 5.6e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNZ80306.1 - 1.4e-07 31.3 0.0 8.8e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 KNZ80306.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DLH PF01738.18 KNZ80307.1 - 9.8e-11 41.6 0.0 2.5e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family AAA PF00004.29 KNZ80308.1 - 6.2e-86 285.5 0.0 1.6e-42 145.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ80308.1 - 2e-21 75.5 0.0 6.5e-12 45.1 0.0 3.1 4 0 0 4 4 2 2 AAA+ lid domain AAA_16 PF13191.6 KNZ80308.1 - 1.5e-11 45.0 2.0 2.1e-06 28.2 0.2 3.9 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 KNZ80308.1 - 2.9e-11 43.4 0.0 0.00044 20.0 0.0 3.4 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNZ80308.1 - 3.4e-11 43.3 0.0 1.7e-05 24.8 0.0 4.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNZ80308.1 - 8.1e-11 42.3 0.0 0.00049 20.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KNZ80308.1 - 2.5e-08 34.3 0.5 0.00067 19.9 0.0 4.4 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KNZ80308.1 - 2.1e-07 31.2 0.0 0.00038 20.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 KNZ80308.1 - 3.6e-07 30.1 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 KNZ80308.1 - 5.9e-07 29.0 0.0 0.0068 15.6 0.0 2.5 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_14 PF13173.6 KNZ80308.1 - 6.2e-06 26.3 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 KNZ80308.1 - 0.00011 21.7 0.1 0.19 11.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KNZ80308.1 - 0.00021 20.9 2.9 4 7.0 0.1 4.3 2 2 2 4 4 4 1 AAA domain TsaE PF02367.17 KNZ80308.1 - 0.00032 20.7 0.0 0.099 12.6 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KNZ80308.1 - 0.00036 20.5 0.1 0.048 13.6 0.0 3.4 4 0 0 4 4 3 1 NACHT domain RNA_helicase PF00910.22 KNZ80308.1 - 0.00037 20.8 0.0 0.049 14.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 KNZ80308.1 - 0.00089 19.2 0.6 0.29 11.0 0.1 3.4 2 2 1 3 3 3 1 Rad17 P-loop domain Zeta_toxin PF06414.12 KNZ80308.1 - 0.0014 18.0 0.0 0.029 13.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 KNZ80308.1 - 0.0017 18.2 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KNZ80308.1 - 0.0027 18.2 0.0 0.0091 16.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 KNZ80308.1 - 0.0035 17.1 0.0 0.053 13.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 KNZ80308.1 - 0.0037 17.5 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 KNZ80308.1 - 0.0069 16.2 0.0 0.59 9.9 0.0 3.0 3 1 0 3 3 3 1 Bacterial dnaA protein AAA_7 PF12775.7 KNZ80308.1 - 0.0078 15.7 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Viral_helicase1 PF01443.18 KNZ80308.1 - 0.01 15.6 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 KNZ80308.1 - 0.017 15.0 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KNZ80308.1 - 0.029 14.1 0.0 0.87 9.3 0.0 3.1 2 1 0 2 2 2 0 Sigma-54 interaction domain DAP3 PF10236.9 KNZ80308.1 - 0.045 12.9 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Vps4_C PF09336.10 KNZ80308.1 - 0.05 13.6 0.1 26 4.9 0.0 3.8 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.17 KNZ80308.1 - 0.052 12.6 0.0 0.25 10.4 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KNZ80308.1 - 0.057 12.9 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 KNZ80308.1 - 0.062 12.6 0.0 8.4 5.7 0.0 2.6 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 KNZ80308.1 - 0.091 12.9 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 KNZ80308.1 - 0.1 13.1 0.0 0.74 10.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 KNZ80308.1 - 0.12 12.2 0.0 7.4 6.4 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 KNZ80308.1 - 0.13 11.1 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 KNZ80308.1 - 0.15 12.4 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ80308.1 - 0.17 11.6 0.0 0.59 9.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 KNZ80308.1 - 0.22 11.4 0.5 2.3 8.1 0.0 2.9 3 2 1 4 4 3 0 NTPase Gpi16 PF04113.14 KNZ80309.1 - 4.9e-139 464.3 0.1 1.9e-137 459.1 0.1 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component F1F0-ATPsyn_F PF10791.9 KNZ80311.1 - 2.5e-25 88.8 0.0 3.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi AAA_29 PF13555.6 KNZ80311.1 - 0.22 11.3 1.8 4 7.3 0.2 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain CPBP PF02517.16 KNZ80312.1 - 7.8e-16 58.2 3.8 7.8e-16 58.2 3.8 2.7 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Mhr1 PF12829.7 KNZ80313.1 - 0.0077 16.3 0.2 0.094 12.8 0.1 2.1 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Mannosidase_ig PF17786.1 KNZ80314.1 - 1.1e-16 61.2 0.0 4e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KNZ80314.1 - 8.6e-07 29.6 0.2 5.9e-06 26.9 0.1 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KNZ80314.1 - 0.031 14.0 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Ig-fold domain Glyco_hydro_2_N PF02837.18 KNZ80314.1 - 0.04 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain F-box PF00646.33 KNZ80315.1 - 0.00019 21.2 6.8 0.022 14.6 0.3 2.6 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 KNZ80315.1 - 0.041 13.8 0.2 0.041 13.8 0.2 2.6 3 0 0 3 3 3 0 F-box-like ELK PF03789.13 KNZ80315.1 - 0.097 12.8 4.3 0.2 11.8 4.3 1.5 1 0 0 1 1 1 0 ELK domain PUL PF08324.11 KNZ80316.1 - 1.5e-40 139.2 1.9 2.5e-40 138.5 1.9 1.4 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 KNZ80316.1 - 1.2e-38 132.3 0.0 1.8e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KNZ80316.1 - 4.8e-15 55.4 0.0 9.1e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNZ80316.1 - 3.3e-05 24.3 0.0 0.00025 21.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KNZ80316.1 - 0.0086 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KNZ80316.1 - 0.042 13.7 1.5 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 F plasmid transfer operon protein ArfGap PF01412.18 KNZ80317.1 - 9.1e-33 112.8 0.5 9.1e-33 112.8 0.5 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.6 KNZ80318.1 - 4.4e-44 150.8 0.0 4.8e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ80318.1 - 1.7e-31 109.2 0.0 1.9e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ80318.1 - 0.0021 18.0 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 KR domain CholecysA-Rec_N PF09193.10 KNZ80318.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal Asp PF00026.23 KNZ80319.1 - 1e-10 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ80319.1 - 0.0042 17.3 0.0 0.027 14.7 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal LRR_4 PF12799.7 KNZ80320.1 - 0.072 13.5 12.8 13 6.4 0.3 5.8 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KNZ80320.1 - 0.61 10.3 2.0 4 7.8 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Retrotran_gag_2 PF14223.6 KNZ80321.1 - 5.2e-10 39.1 0.0 1.2e-09 38.0 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.6 KNZ80321.1 - 0.23 11.2 1.0 0.66 9.8 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle ATP_bind_3 PF01171.20 KNZ80322.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 PP-loop family LRR_4 PF12799.7 KNZ80322.1 - 0.36 11.3 11.6 16 6.0 0.3 5.9 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) Chromo PF00385.24 KNZ80323.1 - 2.6e-08 33.6 0.1 4.9e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LRR_4 PF12799.7 KNZ80323.1 - 0.00025 21.3 3.4 0.73 10.3 0.3 4.8 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KNZ80323.1 - 0.00026 20.8 0.2 0.0009 19.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like ATP_bind_3 PF01171.20 KNZ80323.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 PP-loop family Chromo PF00385.24 KNZ80324.1 - 1.8e-16 59.8 0.2 2.3e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ80324.1 - 0.02 15.0 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SAWADEE PF16719.5 KNZ80324.1 - 0.12 12.4 0.1 0.13 12.3 0.1 1.0 1 0 0 1 1 1 0 SAWADEE domain Isochorismatase PF00857.20 KNZ80325.1 - 0.091 12.9 1.1 0.24 11.6 0.1 2.3 2 1 0 2 2 2 0 Isochorismatase family PIF1 PF05970.14 KNZ80326.1 - 4e-33 115.1 0.0 4.3e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ80326.1 - 0.0032 17.2 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal SPC25 PF06703.11 KNZ80327.1 - 1.8e-52 177.4 0.0 2.1e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) GMC_oxred_N PF00732.19 KNZ80328.1 - 9.1e-32 110.6 0.0 6.4e-31 107.8 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ80328.1 - 6.4e-25 88.4 0.0 1.5e-24 87.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KNZ80328.1 - 3.7e-05 23.1 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ80328.1 - 0.00066 19.9 1.6 0.0017 18.5 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ80328.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ80328.1 - 0.002 17.2 0.5 0.0033 16.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KNZ80328.1 - 0.018 14.3 0.0 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KNZ80328.1 - 0.02 14.5 0.4 0.041 13.5 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KNZ80328.1 - 0.043 13.1 0.1 0.076 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KNZ80328.1 - 0.053 12.2 0.5 0.093 11.4 0.3 1.5 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 KNZ80328.1 - 0.11 11.5 0.3 0.21 10.6 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KNZ80328.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KNZ80328.1 - 0.18 11.3 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ABC_tran PF00005.27 KNZ80330.1 - 9.9e-41 139.5 0.0 5.9e-22 78.7 0.1 3.4 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KNZ80330.1 - 3.8e-25 89.1 14.3 1.9e-21 76.9 5.5 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.19 KNZ80330.1 - 1.3e-06 28.1 0.0 0.0048 16.4 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KNZ80330.1 - 0.22 11.3 1.1 15 5.4 0.1 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Malic_M PF03949.15 KNZ80331.1 - 5.6e-86 288.0 0.0 7e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KNZ80331.1 - 7.2e-67 224.7 0.0 1e-66 224.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain adh_short_C2 PF13561.6 KNZ80332.1 - 1.9e-55 187.9 0.0 2.5e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ80332.1 - 1.1e-50 171.8 0.0 1.4e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ80332.1 - 2.1e-15 57.1 0.0 2.7e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ80332.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KNZ80332.1 - 0.058 12.5 0.0 0.77 8.8 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KNZ80332.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family ADH_N PF08240.12 KNZ80333.1 - 1.6e-27 95.5 0.4 3.4e-27 94.5 0.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ80333.1 - 5.3e-22 78.2 0.2 8.4e-22 77.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KNZ80333.1 - 1.4e-09 37.8 0.1 8.5e-05 22.1 0.0 2.6 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KNZ80333.1 - 1.6e-05 26.0 0.0 3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KNZ80333.1 - 0.0008 18.8 0.1 0.0023 17.3 0.1 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 KNZ80333.1 - 0.022 14.3 0.4 0.039 13.5 0.1 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.13 KNZ80333.1 - 0.04 13.3 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.19 KNZ80333.1 - 0.086 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 KNZ80333.1 - 0.15 12.8 0.1 0.34 11.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain YdfZ PF14001.6 KNZ80333.1 - 0.42 11.1 3.5 1.8 9.0 0.0 3.2 4 0 0 4 4 4 0 YdfZ protein Dus PF01207.17 KNZ80334.1 - 3.5e-56 190.6 0.0 6.2e-56 189.8 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 KNZ80334.1 - 0.039 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KNZ80334.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein GldM_N PF12081.8 KNZ80336.1 - 1.5e-06 28.4 16.5 0.00043 20.4 6.2 2.4 1 1 1 2 2 2 2 GldM N-terminal domain GRAB PF10375.9 KNZ80336.1 - 0.00012 21.8 0.4 0.00012 21.8 0.4 1.9 2 0 0 2 2 2 1 GRIP-related Arf-binding domain LPP PF04728.13 KNZ80336.1 - 0.0002 21.6 1.8 0.00092 19.5 1.8 2.2 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 KNZ80336.1 - 7.9 6.6 47.9 4.6 7.4 24.2 2.9 1 1 2 3 3 3 0 Tropomyosin like F-box-like PF12937.7 KNZ80337.1 - 1.2e-05 25.1 0.1 2.9e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like Herpes_Helicase PF02689.14 KNZ80338.1 - 0.00023 19.3 0.0 0.00024 19.2 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ80338.1 - 0.098 12.5 0.2 0.2 11.5 0.2 1.6 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ80339.1 - 2.1e-26 92.9 0.0 2.3e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Viral_helicase1 PF01443.18 KNZ80339.1 - 0.0013 18.5 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 KNZ80339.1 - 0.066 13.6 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 KNZ80339.1 - 0.077 13.0 0.0 0.25 11.3 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KNZ80339.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.22 KNZ80339.1 - 0.15 12.4 0.1 0.19 12.1 0.1 1.5 1 1 0 1 1 1 0 RNA helicase RRM_1 PF00076.22 KNZ80340.1 - 3.6e-38 129.2 0.0 5e-21 74.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.6 KNZ80340.1 - 0.068 13.5 0.0 22 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) Histone PF00125.24 KNZ80341.1 - 7.8e-18 65.1 0.0 9.8e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KNZ80341.1 - 3.9e-17 61.7 0.3 6.9e-17 60.9 0.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KNZ80341.1 - 2.7e-06 27.6 0.0 4.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ80342.1 - 1.2e-23 83.8 1.9 1.7e-23 83.4 1.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KNZ80342.1 - 1.3e-05 25.3 0.1 3.7e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KNZ80342.1 - 0.00029 21.3 0.0 0.00056 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 KNZ80342.1 - 0.06 13.6 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 CENP-W protein Bt_P21 PF05560.11 KNZ80342.1 - 0.098 12.2 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF768 PF05589.11 KNZ80343.1 - 0.15 12.1 0.0 10 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF768) zf-C2H2_4 PF13894.6 KNZ80344.1 - 2.1e-07 31.2 6.3 0.0052 17.5 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ80344.1 - 4.7e-07 29.9 8.7 0.00037 20.8 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 KNZ80344.1 - 0.00025 21.3 0.0 0.00077 19.8 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 KNZ80344.1 - 0.0021 18.4 3.3 0.57 10.6 0.2 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 KNZ80344.1 - 0.0045 17.3 13.4 0.051 14.0 1.1 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KNZ80344.1 - 0.017 15.4 2.6 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KNZ80344.1 - 0.024 14.9 3.3 3 8.2 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 KNZ80344.1 - 0.1 12.4 2.3 0.2 11.5 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 KNZ80344.1 - 0.61 10.1 2.9 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger HECT PF00632.25 KNZ80345.1 - 1.4e-89 300.6 0.0 1.8e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KNZ80345.1 - 0.15 12.0 0.0 0.58 10.1 0.0 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif FAM176 PF14851.6 KNZ80347.1 - 0.015 15.0 0.4 7.1 6.3 0.0 2.2 2 0 0 2 2 2 0 FAM176 family EphA2_TM PF14575.6 KNZ80347.1 - 0.02 15.8 0.1 0.054 14.4 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain OppC_N PF12911.7 KNZ80347.1 - 0.039 13.9 0.8 0.039 13.9 0.8 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3245 PF11595.8 KNZ80347.1 - 0.039 14.4 1.9 0.083 13.4 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) OAD_gamma PF04277.13 KNZ80347.1 - 0.041 14.5 0.5 0.11 13.1 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TMEM154 PF15102.6 KNZ80347.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.2 2 1 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.16 KNZ80347.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ubiquitin PF00240.23 KNZ80348.1 - 1e-18 66.8 0.0 1.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KNZ80348.1 - 3.1e-09 36.5 0.4 3.1e-09 36.5 0.4 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 KNZ80348.1 - 1e-07 31.7 0.1 1.6e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KNZ80348.1 - 1.5e-05 25.5 0.0 6.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KNZ80348.1 - 0.019 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 KNZ80348.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 KNZ80348.1 - 0.11 12.6 0.5 11 6.2 0.3 2.5 2 1 1 3 3 3 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 KNZ80348.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 KNZ80348.1 - 0.47 10.4 2.2 0.7 9.9 0.9 1.8 1 1 1 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 KNZ80348.1 - 1.1 9.3 15.6 1.1 9.2 6.3 3.3 3 1 0 3 3 3 0 STI1 domain XPC-binding PF09280.11 KNZ80348.1 - 1.6 8.6 12.9 0.83 9.4 3.5 3.5 2 1 1 3 3 3 0 XPC-binding domain Aldo_ket_red PF00248.21 KNZ80349.1 - 3.1e-42 144.8 0.0 1.8e-40 139.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MIOX PF05153.15 KNZ80351.1 - 4.7e-127 422.7 0.3 5.6e-127 422.5 0.3 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 KNZ80351.1 - 0.0031 17.7 0.1 0.047 13.9 0.0 2.3 2 0 0 2 2 2 1 HD domain Cytochrom_C_2 PF01322.20 KNZ80351.1 - 0.0048 17.8 0.4 0.0084 17.0 0.4 1.3 1 0 0 1 1 1 1 Cytochrome C' HDOD PF08668.12 KNZ80351.1 - 0.14 11.6 0.0 0.34 10.3 0.0 1.6 1 1 0 1 1 1 0 HDOD domain UBD PF16455.5 KNZ80351.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain HAD PF12710.7 KNZ80352.1 - 2.6e-23 83.4 0.0 3.4e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KNZ80352.1 - 1.8e-05 24.3 0.0 5.1e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 KNZ80352.1 - 0.00016 21.3 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KNZ80352.1 - 0.00048 20.5 0.1 0.014 15.7 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KNZ80352.1 - 0.04 14.0 0.0 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GGACT PF06094.12 KNZ80354.1 - 3.9e-10 40.4 0.1 5.2e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 KNZ80354.1 - 1e-09 38.6 0.1 1.4e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family GPI2 PF06432.11 KNZ80355.1 - 4.8e-46 157.5 17.4 5.3e-46 157.3 17.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Proteasome PF00227.26 KNZ80356.1 - 2.6e-49 167.3 0.1 3.3e-49 167.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit AA_permease PF00324.21 KNZ80357.1 - 4.5e-111 371.8 30.8 5.4e-111 371.5 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ80357.1 - 3e-21 75.8 34.4 4e-21 75.4 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease LIM PF00412.22 KNZ80358.1 - 5.1e-13 49.0 23.7 0.00016 21.8 2.7 5.0 5 0 0 5 5 5 4 LIM domain Ferlin_C PF16165.5 KNZ80358.1 - 0.23 11.4 1.8 0.54 10.2 1.8 1.6 1 0 0 1 1 1 0 Ferlin C-terminus zf_UBZ PF18439.1 KNZ80358.1 - 2.4 7.8 10.6 3 7.5 0.0 4.1 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger Vps39_2 PF10367.9 KNZ80358.1 - 6.6 7.2 6.6 0.59 10.6 0.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Sgf11 PF08209.11 KNZ80358.1 - 8.1 6.1 9.1 3.1 7.4 0.2 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) RdRP PF05183.12 KNZ80359.1 - 9.4e-141 470.3 0.0 1.2e-140 470.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase CTP_transf_like PF01467.26 KNZ80359.1 - 5.8e-08 33.0 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Transket_pyr PF02779.24 KNZ80360.1 - 1.1e-40 139.2 0.0 1.6e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KNZ80360.1 - 1.6e-27 95.8 0.0 7e-27 93.8 0.0 2.1 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.32 KNZ80361.1 - 1.1e-06 29.3 10.4 0.031 15.2 0.1 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ80361.1 - 0.00043 20.5 0.0 0.35 11.2 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KNZ80361.1 - 0.01 14.4 0.0 0.046 12.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain ANAPC15 PF15243.6 KNZ80362.1 - 0.0049 17.2 0.8 0.0049 17.2 0.8 2.6 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 15 DASH_Dam1 PF08653.10 KNZ80362.1 - 1.3 8.9 3.7 2 8.2 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 MTHFR PF02219.17 KNZ80363.1 - 4.5e-100 334.7 0.0 2.1e-99 332.5 0.0 1.8 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase PBP PF01161.20 KNZ80363.1 - 0.0031 17.8 0.0 0.099 13.0 0.0 2.6 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Ras PF00071.22 KNZ80364.1 - 1.8e-59 199.9 0.4 2.3e-59 199.6 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ80364.1 - 2e-37 128.1 0.1 3.4e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ80364.1 - 2.9e-16 59.4 0.1 3.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KNZ80364.1 - 5e-07 29.3 0.3 8.8e-07 28.5 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KNZ80364.1 - 2.1e-06 27.4 0.4 2.4e-05 24.0 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KNZ80364.1 - 7.2e-06 25.5 0.5 9.5e-06 25.1 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ80364.1 - 8.6e-06 25.8 0.1 4.5e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ80364.1 - 5.5e-05 23.1 0.1 0.014 15.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 KNZ80364.1 - 0.00062 19.3 0.5 0.023 14.2 0.5 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 KNZ80364.1 - 0.03 13.7 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein Dynamin_N PF00350.23 KNZ80364.1 - 0.037 14.1 0.1 2.3 8.2 0.0 2.7 2 1 1 3 3 3 0 Dynamin family DLIC PF05783.11 KNZ80364.1 - 0.05 12.4 0.0 0.086 11.7 0.0 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) CPT PF07931.12 KNZ80364.1 - 0.063 13.1 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 KNZ80364.1 - 0.081 12.7 1.4 0.36 10.6 1.4 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 KNZ80364.1 - 0.13 12.7 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TAP42 PF04177.12 KNZ80365.1 - 2.2e-84 283.3 1.5 2.4e-84 283.2 1.5 1.0 1 0 0 1 1 1 1 TAP42-like family GAGBD PF16828.5 KNZ80365.1 - 0.11 12.5 2.5 0.13 12.4 1.3 1.7 2 0 0 2 2 2 0 GAG-binding domain on surface antigen PI3_PI4_kinase PF00454.27 KNZ80366.1 - 1.1e-35 123.6 0.3 4e-33 115.3 0.1 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KNZ80366.1 - 2.4e-23 82.5 0.1 8.8e-23 80.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PYRIN PF02758.16 KNZ80366.1 - 0.0097 16.0 0.1 0.2 11.8 0.1 2.8 2 0 0 2 2 2 1 PAAD/DAPIN/Pyrin domain DUF4135 PF13575.6 KNZ80366.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Peptidase_M28 PF04389.17 KNZ80367.1 - 6.1e-33 114.2 0.0 9.5e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Sybindin PF04099.12 KNZ80368.1 - 1.3e-38 132.1 0.0 1.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KNZ80368.1 - 2.9e-09 37.1 0.0 3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HORMA PF02301.18 KNZ80369.1 - 2.7e-67 226.5 1.2 4.5e-67 225.7 0.0 1.9 2 0 0 2 2 2 1 HORMA domain PHD PF00628.29 KNZ80369.1 - 0.012 15.5 9.5 0.02 14.8 9.5 1.4 1 0 0 1 1 1 0 PHD-finger PFU PF09070.11 KNZ80370.1 - 3.5e-43 146.4 0.1 7.2e-43 145.5 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.11 KNZ80370.1 - 5e-41 140.7 0.5 6.8e-41 140.3 0.5 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 KNZ80370.1 - 3.7e-30 103.5 13.4 1.2e-07 32.2 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 KNZ80370.1 - 4.2e-05 23.5 0.0 0.096 12.7 0.0 3.0 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Ntox37 PF15535.6 KNZ80370.1 - 0.22 12.0 1.9 6.3 7.3 0.4 2.6 1 1 1 2 2 2 0 Bacterial toxin 37 His_Phos_1 PF00300.22 KNZ80371.1 - 1.2e-35 123.0 0.3 3.8e-35 121.4 0.3 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LysR_substrate PF03466.20 KNZ80371.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain DUF3371 PF11851.8 KNZ80371.1 - 0.065 14.3 0.0 0.097 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Na_Ca_ex PF01699.24 KNZ80372.1 - 3.9e-42 143.7 30.0 8.4e-22 77.7 14.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.12 KNZ80372.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.6 2 1 2 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Neurensin PF14927.6 KNZ80372.1 - 0.4 10.4 2.5 8.8 6.0 0.0 3.4 1 1 2 3 3 3 0 Neurensin LRR_4 PF12799.7 KNZ80373.1 - 0.0052 17.2 0.0 2.2 8.8 0.0 4.2 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) Asparaginase PF00710.20 KNZ80374.1 - 8e-50 169.0 0.0 1.9e-49 167.8 0.0 1.6 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KNZ80374.1 - 1.5e-29 102.5 0.0 2.7e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KNZ80374.1 - 5.3e-13 49.4 0.1 1.1e-12 48.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KNZ80374.1 - 6.7e-10 39.0 0.9 0.00024 21.4 0.5 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KNZ80374.1 - 8.3e-10 38.1 0.2 8e-05 22.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KNZ80374.1 - 1.2e-08 35.4 0.8 0.00014 22.4 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ80374.1 - 9.2e-08 32.2 0.5 1.9e-05 24.9 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Trp_syntA PF00290.20 KNZ80375.1 - 7.9e-77 257.6 1.6 1.3e-75 253.6 1.6 2.1 1 1 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 KNZ80375.1 - 3.5e-44 151.4 0.3 5.5e-44 150.7 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NMO PF03060.15 KNZ80375.1 - 1.7e-05 24.4 0.1 2.7e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 KNZ80375.1 - 5.8e-05 22.7 0.1 0.00015 21.3 0.1 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 KNZ80375.1 - 0.071 12.4 0.2 0.24 10.7 0.2 1.8 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG IF-2B PF01008.17 KNZ80376.1 - 4.2e-67 226.3 0.0 5.6e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.27 KNZ80377.1 - 3.5e-47 160.5 0.1 5.6e-47 159.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KNZ80377.1 - 1.5e-39 134.5 0.7 1.2e-36 125.1 0.4 2.5 2 0 0 2 2 2 2 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KNZ80377.1 - 5.8e-18 64.7 0.0 1.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ80377.1 - 3.7e-10 40.0 0.1 8.1e-10 39.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ80377.1 - 3.8e-06 27.0 0.0 8.4e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 KNZ80377.1 - 9.7e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 KNZ80377.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 KNZ80377.1 - 0.00017 21.3 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 KNZ80377.1 - 0.015 14.8 0.0 0.055 13.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 KNZ80377.1 - 0.016 14.6 0.2 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 KNZ80377.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Asp_protease_2 PF13650.6 KNZ80378.1 - 0.00082 20.0 0.0 0.0023 18.5 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ80378.1 - 0.0048 17.4 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-C2H2_10 PF16588.5 KNZ80378.1 - 0.44 10.3 2.2 0.9 9.3 2.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger Laps PF10169.9 KNZ80380.1 - 1.8 9.1 7.5 0.31 11.6 1.8 2.4 2 0 0 2 2 2 0 Learning-associated protein Retrotrans_gag PF03732.17 KNZ80382.1 - 0.0038 17.5 0.1 0.0052 17.0 0.1 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein p450 PF00067.22 KNZ80387.1 - 1.3e-64 218.7 0.0 1.6e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GCP_N_terminal PF17681.1 KNZ80388.1 - 0.087 12.4 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal SSF PF00474.17 KNZ80389.1 - 2.3e-21 76.1 26.2 2.2e-20 72.9 26.2 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family adh_short PF00106.25 KNZ80391.1 - 2.2e-39 135.0 2.2 1.6e-28 99.5 0.6 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ80391.1 - 1.8e-31 109.5 2.3 2.1e-21 76.6 1.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ80391.1 - 1.2e-05 25.3 0.6 5.9e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 KNZ80391.1 - 0.0018 18.2 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DsrD PF08679.11 KNZ80391.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.3 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) Epimerase PF01370.21 KNZ80391.1 - 0.022 14.2 0.1 0.044 13.2 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 KNZ80391.1 - 0.059 14.0 0.3 0.16 12.6 0.3 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Methyltransf_25 PF13649.6 KNZ80391.1 - 0.065 13.9 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HCV_NS5a_1b PF08301.13 KNZ80391.1 - 0.078 13.6 0.0 0.24 12.0 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b p450 PF00067.22 KNZ80392.1 - 1.4e-50 172.4 0.0 2.1e-50 171.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Solute_trans_a PF03619.16 KNZ80394.1 - 1.8e-92 309.7 12.4 2.1e-92 309.4 12.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Redoxin PF08534.10 KNZ80395.1 - 9.1e-36 122.8 0.0 1e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KNZ80395.1 - 1.1e-10 41.4 0.0 1.3e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MFS_1 PF07690.16 KNZ80396.1 - 1.9e-42 145.5 27.2 1.9e-42 145.5 27.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ80396.1 - 1.3e-17 63.8 2.7 1.3e-17 63.8 2.7 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter ABC_tran PF00005.27 KNZ80397.1 - 3.1e-22 79.6 0.0 6.3e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KNZ80397.1 - 3.1e-08 33.8 0.1 0.00041 20.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KNZ80397.1 - 2.4e-06 27.2 0.3 0.047 13.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KNZ80397.1 - 0.00017 21.9 0.0 0.0074 16.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KNZ80397.1 - 0.00034 20.4 0.2 0.00056 19.7 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KNZ80397.1 - 0.00059 19.5 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KNZ80397.1 - 0.00089 19.2 0.2 0.002 18.0 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 KNZ80397.1 - 0.0038 16.4 0.3 0.0088 15.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KNZ80397.1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KNZ80397.1 - 0.0098 16.1 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KNZ80397.1 - 0.011 16.2 0.1 0.021 15.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KNZ80397.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 KNZ80397.1 - 0.015 15.3 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 KNZ80397.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 KNZ80397.1 - 0.027 15.0 0.1 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ80397.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KNZ80397.1 - 0.035 14.3 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KNZ80397.1 - 0.047 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SRPRB PF09439.10 KNZ80397.1 - 0.059 12.8 0.1 8.6 5.8 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit ABC_ATPase PF09818.9 KNZ80397.1 - 0.074 11.8 0.1 0.86 8.3 0.1 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NACHT PF05729.12 KNZ80397.1 - 0.14 12.1 0.3 0.46 10.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 KNZ80397.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin Ndc1_Nup PF09531.10 KNZ80398.1 - 2.1e-85 287.7 8.1 2.5e-85 287.5 8.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Silic_transp PF03842.13 KNZ80398.1 - 0.0041 15.5 1.6 0.0059 15.0 1.6 1.2 1 0 0 1 1 1 1 Silicon transporter MFS_1 PF07690.16 KNZ80400.1 - 8.3e-44 149.9 35.4 8.3e-44 149.9 35.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ80400.1 - 1e-15 57.5 9.7 1e-15 57.5 9.7 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KNZ80400.1 - 3.8e-08 33.0 5.5 3.8e-08 33.0 5.5 2.6 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KNZ80400.1 - 7.3e-06 24.7 6.5 7.3e-06 24.7 6.5 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KNZ80400.1 - 1.6 6.9 22.6 0.049 11.9 2.4 3.2 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_C21 PF05381.12 KNZ80402.1 - 0.029 14.7 0.2 0.064 13.6 0.2 1.5 1 0 0 1 1 1 0 Tymovirus endopeptidase zf-RING_11 PF17123.5 KNZ80403.1 - 2.3e-12 46.4 8.7 4.3e-12 45.6 8.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KNZ80403.1 - 3.2e-09 37.0 11.1 5.5e-09 36.2 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ80403.1 - 1.7e-05 24.6 11.2 2.6e-05 23.9 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ80403.1 - 2.6e-05 24.0 10.8 4e-05 23.4 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KNZ80403.1 - 6.6e-05 23.1 7.7 0.00016 21.9 7.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KNZ80403.1 - 0.00014 21.9 2.4 0.00022 21.2 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KNZ80403.1 - 0.00035 20.5 9.0 0.0006 19.7 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KNZ80403.1 - 0.0056 16.7 10.3 0.01 15.9 10.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KNZ80403.1 - 0.009 15.9 6.8 0.015 15.1 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KNZ80403.1 - 0.01 15.7 5.3 0.018 14.9 5.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 KNZ80403.1 - 0.014 15.5 1.5 0.014 15.5 1.5 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KNZ80403.1 - 0.057 13.0 5.8 0.11 12.1 5.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 KNZ80403.1 - 0.069 12.5 0.0 0.078 12.3 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_4 PF14447.6 KNZ80403.1 - 0.24 11.3 8.2 0.43 10.5 8.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Glyco_hydro_11 PF00457.17 KNZ80404.1 - 4.6e-72 241.4 13.3 5.4e-72 241.1 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Peptidase_S8 PF00082.22 KNZ80405.1 - 8.9e-26 90.8 1.9 9.8e-26 90.7 1.9 1.1 1 0 0 1 1 1 1 Subtilase family DUF4082 PF13313.6 KNZ80405.1 - 0.029 14.4 0.2 9.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) RVT_1 PF00078.27 KNZ80406.1 - 0.14 11.7 0.1 0.16 11.5 0.1 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1769 PF08588.10 KNZ80408.1 - 2.3e-21 75.7 0.1 6.8e-21 74.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Sugar_tr PF00083.24 KNZ80409.1 - 1.8e-90 304.0 12.9 2.1e-90 303.8 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ80409.1 - 1.5e-18 66.9 27.9 1.1e-13 50.8 13.8 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 KNZ80409.1 - 0.16 10.2 6.4 0.023 13.0 1.3 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-MYND PF01753.18 KNZ80410.1 - 7.4e-06 26.0 14.8 1.2e-05 25.3 14.8 1.3 1 0 0 1 1 1 1 MYND finger Fungal_trans PF04082.18 KNZ80411.1 - 6.1e-10 38.6 3.0 6e-09 35.3 3.0 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SPT6_acidic PF14632.6 KNZ80411.1 - 0.017 15.7 3.5 0.041 14.5 3.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 DUF3446 PF11928.8 KNZ80411.1 - 0.041 14.2 9.7 0.13 12.6 9.7 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain Lipoprotein_7 PF01540.16 KNZ80413.1 - 0.011 15.1 4.8 0.013 14.8 4.8 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein TFIID-18kDa PF02269.16 KNZ80413.1 - 0.15 12.1 0.5 0.32 11.1 0.5 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SWI-SNF_Ssr4 PF08549.10 KNZ80413.1 - 1.3 7.6 10.2 5.2 5.6 9.7 2.0 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-CSL PF05207.13 KNZ80414.1 - 3.6e-21 74.6 0.4 3.6e-21 74.6 0.4 1.7 2 1 0 2 2 2 1 CSL zinc finger Zn-ribbon_8 PF09723.10 KNZ80414.1 - 0.0021 18.1 0.8 0.0041 17.2 0.8 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Lar_restr_allev PF14354.6 KNZ80414.1 - 0.035 14.5 0.4 0.064 13.6 0.4 1.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF688 PF05097.12 KNZ80414.1 - 0.036 13.2 1.0 0.037 13.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Sigma70_ner PF04546.13 KNZ80414.1 - 0.23 11.3 7.2 0.23 11.3 7.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 KNZ80414.1 - 1.7 7.1 6.6 1.7 7.1 6.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mito_carr PF00153.27 KNZ80415.1 - 1.3e-19 69.9 6.7 5.5e-09 35.8 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein YqfD PF06898.11 KNZ80415.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD TPR_1 PF00515.28 KNZ80416.1 - 3.2e-35 118.5 7.9 1.5e-05 24.6 0.0 11.4 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ80416.1 - 4e-31 104.6 16.2 0.00077 19.4 0.0 10.9 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ80416.1 - 1.9e-21 75.5 3.9 3e-08 33.2 0.0 6.6 4 2 2 6 6 6 4 TPR repeat TPR_8 PF13181.6 KNZ80416.1 - 1.6e-17 62.2 8.0 0.0006 19.8 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ80416.1 - 1.7e-14 53.1 2.9 0.074 13.5 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ80416.1 - 3e-14 51.9 5.2 0.14 12.2 0.0 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ80416.1 - 4.2e-13 49.7 19.7 2.7e-06 27.9 0.0 7.0 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ80416.1 - 5.5e-13 49.2 11.3 0.0068 16.9 0.1 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ80416.1 - 2.6e-12 46.9 21.0 0.00024 21.4 0.0 8.7 5 2 4 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ80416.1 - 1.7e-11 43.9 16.4 0.00065 20.3 0.0 8.2 6 4 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ80416.1 - 7.2e-10 38.9 7.4 0.0012 19.0 0.0 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ80416.1 - 5.3e-07 29.8 11.5 0.022 15.0 0.0 5.6 4 2 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KNZ80416.1 - 0.00018 21.9 15.7 1.1 10.1 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF3856 PF12968.7 KNZ80416.1 - 0.00077 19.6 3.9 0.93 9.6 0.0 5.0 5 1 1 6 6 5 1 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 KNZ80416.1 - 0.0021 17.4 5.3 4.1 7.0 0.1 4.9 5 0 0 5 5 4 1 SHNi-TPR TPR_10 PF13374.6 KNZ80416.1 - 0.043 13.7 12.7 1.4 8.9 0.0 6.3 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 KNZ80416.1 - 0.052 13.9 7.6 25 5.3 0.1 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF627 PF04781.12 KNZ80416.1 - 0.061 13.3 2.4 2.2 8.3 0.0 3.9 3 2 0 4 4 3 0 Protein of unknown function (DUF627) Prolamin_like PF05617.11 KNZ80416.1 - 0.091 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Prolamin-like ANAPC5 PF12862.7 KNZ80416.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.4 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 5 SPO22 PF08631.10 KNZ80416.1 - 0.15 11.5 3.5 0.77 9.2 0.4 3.4 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like MAS20 PF02064.15 KNZ80416.1 - 1.8 8.6 11.2 32 4.6 0.0 5.1 3 2 2 5 5 4 0 MAS20 protein import receptor Glyco_hydro_43 PF04616.14 KNZ80417.1 - 3.1e-75 253.2 1.1 4e-75 252.8 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KNZ80417.1 - 4.4e-28 98.4 0.0 6e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF2813 PF11398.8 KNZ80418.1 - 0.0017 17.7 0.2 0.0027 17.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2813) LRR_4 PF12799.7 KNZ80418.1 - 0.054 13.9 8.3 1.2 9.7 0.9 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3712 PF12505.8 KNZ80419.1 - 2e-113 373.8 52.9 9.1e-25 87.3 0.1 8.9 9 0 0 9 9 9 6 Protein of unknown function (DUF3712) LEA_2 PF03168.13 KNZ80419.1 - 9.2e-12 45.4 18.6 0.2 12.2 0.2 8.7 8 0 0 8 8 8 4 Late embryogenesis abundant protein Bactofilin PF04519.13 KNZ80419.1 - 0.013 15.8 0.5 0.055 13.8 0.0 2.3 2 0 0 2 2 2 0 Polymer-forming cytoskeletal MlaD PF02470.20 KNZ80419.1 - 0.037 14.3 0.1 0.4 11.0 0.0 2.8 3 0 0 3 3 3 0 MlaD protein DUF3684 PF12449.8 KNZ80421.1 - 0 1138.4 0.0 0 1137.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 KNZ80421.1 - 0.036 13.9 0.0 0.13 12.1 0.0 1.9 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chitin_synth_2 PF03142.15 KNZ80422.1 - 2.9e-250 831.4 0.0 3.7e-250 831.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 KNZ80422.1 - 1.6e-13 51.1 0.1 1.5e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KNZ80422.1 - 2e-13 50.7 12.6 4e-13 49.7 8.1 3.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 KNZ80422.1 - 0.00019 20.9 0.0 0.0058 16.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KNZ80422.1 - 0.053 13.3 0.0 0.82 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 TPR_16 PF13432.6 KNZ80423.1 - 1.5e-36 124.8 54.0 2.2e-09 37.8 3.2 12.9 11 1 2 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ80423.1 - 1.6e-32 110.0 13.3 2.9e-06 26.9 0.0 12.9 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ80423.1 - 1.6e-31 106.3 46.5 7.7e-05 23.2 0.1 16.2 10 5 6 16 16 16 8 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ80423.1 - 4e-29 100.9 40.8 6.5e-05 23.4 0.1 12.2 10 3 4 14 14 13 7 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ80423.1 - 4.4e-29 98.2 42.9 4.7e-05 23.2 0.1 17.1 20 0 0 20 20 17 6 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ80423.1 - 1.9e-23 80.6 17.4 0.00065 19.7 0.0 14.4 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ80423.1 - 8.3e-22 76.0 20.7 0.077 13.4 0.0 14.9 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ80423.1 - 3.9e-20 71.2 23.2 0.0025 17.4 0.1 12.5 12 2 3 15 15 13 6 TPR repeat TPR_12 PF13424.6 KNZ80423.1 - 1.4e-19 70.2 41.3 0.00044 20.5 0.1 11.6 10 1 2 12 12 11 5 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ80423.1 - 3.6e-16 59.2 20.0 2.2e-07 31.0 0.0 8.4 8 1 1 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 KNZ80423.1 - 6.1e-14 51.0 10.6 0.63 10.2 0.0 11.1 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ80423.1 - 1e-11 44.8 44.4 0.0011 19.0 0.0 11.5 12 1 1 13 13 11 3 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ80423.1 - 5.8e-10 39.2 12.0 0.17 12.6 0.0 11.1 12 0 0 12 12 9 1 Tetratricopeptide repeat DSPc PF00782.20 KNZ80423.1 - 2.5e-05 24.1 0.0 7.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TPR_15 PF13429.6 KNZ80423.1 - 7.8e-05 22.0 20.1 0.14 11.3 0.1 7.6 6 2 1 8 8 8 2 Tetratricopeptide repeat CDKN3 PF05706.12 KNZ80423.1 - 0.00025 20.8 0.1 0.0013 18.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) TPR_MalT PF17874.1 KNZ80423.1 - 0.00025 20.5 0.1 0.00025 20.5 0.1 6.0 5 3 0 6 6 6 1 MalT-like TPR region DUF4919 PF16266.5 KNZ80423.1 - 0.0023 17.9 0.0 3.5 7.5 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4919) TPR_22 PF18833.1 KNZ80423.1 - 0.017 15.2 0.0 0.068 13.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 KNZ80423.1 - 0.03 14.6 16.3 6.1 7.2 0.0 8.1 8 2 1 9 9 8 0 Tetratricopeptide repeat NARP1 PF12569.8 KNZ80423.1 - 0.038 12.9 4.9 3.9 6.3 0.0 3.9 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 FAT PF02259.23 KNZ80423.1 - 0.082 12.1 3.7 8.4 5.5 0.0 3.3 3 0 0 3 3 3 0 FAT domain Y_phosphatase PF00102.27 KNZ80423.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Wzy_C_2 PF11846.8 KNZ80423.1 - 0.18 11.7 2.4 9.5 6.1 0.0 3.1 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ChAPs PF09295.10 KNZ80423.1 - 0.21 10.6 7.6 0.44 9.5 0.3 4.4 5 1 1 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 KNZ80423.1 - 0.24 11.8 3.6 0.62 10.5 0.4 3.0 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation DUF627 PF04781.12 KNZ80423.1 - 0.45 10.5 3.1 22 5.1 0.0 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF627) TPR_21 PF09976.9 KNZ80423.1 - 0.46 10.2 13.3 5.7 6.6 1.4 4.9 4 2 0 4 4 4 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 KNZ80423.1 - 1.7 8.8 4.0 95 3.2 0.2 4.4 5 1 1 6 6 3 0 Fis1 C-terminal tetratricopeptide repeat LETM1 PF07766.13 KNZ80424.1 - 8.1e-25 87.7 1.9 1.1e-11 44.6 0.2 2.1 1 1 1 2 2 2 2 LETM1-like protein DOCK_N PF16172.5 KNZ80427.1 - 2e-112 375.9 0.0 3e-112 375.3 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 KNZ80427.1 - 5.4e-71 239.8 0.1 1.9e-70 238.0 0.1 1.8 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 KNZ80427.1 - 1.4e-56 191.4 0.0 6.1e-54 182.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain in Dock180 and Zizimin proteins DASH_Spc34 PF08657.10 KNZ80428.1 - 0.035 13.9 0.8 0.35 10.6 0.0 2.2 1 1 1 2 2 2 0 DASH complex subunit Spc34 Fmp27_WPPW PF10359.9 KNZ80428.1 - 0.087 11.7 0.4 0.11 11.3 0.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain THOC7 PF05615.13 KNZ80428.1 - 0.11 12.8 1.8 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 SlyX PF04102.12 KNZ80428.1 - 0.19 12.4 4.8 2.2 8.9 0.2 3.3 3 0 0 3 3 3 0 SlyX Seryl_tRNA_N PF02403.22 KNZ80428.1 - 0.21 11.9 0.8 0.54 10.5 0.8 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain APG5 PF04106.12 KNZ80429.1 - 2.6e-63 213.7 0.0 3.2e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1115 PF06544.12 KNZ80429.1 - 0.091 12.9 0.0 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) AMP-binding PF00501.28 KNZ80430.1 - 2.3e-13 49.5 0.0 3.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KNZ80430.1 - 0.0027 17.6 0.1 0.01 15.7 0.1 1.9 1 1 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Dfp1_Him1_M PF08630.10 KNZ80431.1 - 1.2e-29 103.1 0.1 3.7e-29 101.5 0.1 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KNZ80431.1 - 5.1e-16 58.5 0.4 1.1e-15 57.4 0.4 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.26 KNZ80431.1 - 8.7e-05 22.8 0.1 0.00019 21.7 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KNZ80431.1 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KNZ80431.1 - 0.0034 17.8 0.1 0.0096 16.3 0.1 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Herpes_capsid PF06112.11 KNZ80431.1 - 0.044 13.8 1.1 0.087 12.9 1.1 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Zn_clus PF00172.18 KNZ80433.1 - 0.22 11.7 12.5 0.12 12.6 5.0 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PP2C PF00481.21 KNZ80434.1 - 6.6e-22 78.4 0.0 9.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SAM_decarbox PF01536.16 KNZ80435.1 - 2.2e-106 355.9 0.0 2.5e-106 355.7 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1279 PF06916.13 KNZ80437.1 - 2.4e-18 66.5 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RPEL PF02755.15 KNZ80438.1 - 0.00055 19.5 1.1 0.00079 19.0 0.1 1.9 2 0 0 2 2 2 1 RPEL repeat DUF3510 PF12022.8 KNZ80438.1 - 0.056 13.8 0.6 0.095 13.1 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) UTP15_C PF09384.10 KNZ80438.1 - 0.087 12.5 0.2 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 UTP15 C terminal CbiG_mid PF11761.8 KNZ80439.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis central region Rax2 PF12768.7 KNZ80440.1 - 2.8e-43 147.9 2.7 2.6e-39 134.9 0.3 5.0 3 1 1 4 4 4 1 Cortical protein marker for cell polarity SH3_1 PF00018.28 KNZ80440.1 - 7.8e-10 38.2 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Kelch_6 PF13964.6 KNZ80440.1 - 2.6e-09 37.0 8.1 1 9.7 0.1 6.6 6 0 0 6 6 6 3 Kelch motif SH3_9 PF14604.6 KNZ80440.1 - 9.2e-08 31.8 0.3 2e-07 30.7 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_4 PF13418.6 KNZ80440.1 - 1e-05 25.5 16.1 0.34 11.0 0.1 6.3 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 KNZ80440.1 - 0.00079 19.0 3.6 13 5.4 0.0 5.8 7 0 0 7 7 7 1 Kelch motif DUF5122 PF17164.4 KNZ80440.1 - 0.028 14.7 25.7 17 5.8 0.1 9.5 9 1 1 10 10 10 0 Domain of unknown function (DUF5122) beta-propeller Kelch_3 PF13415.6 KNZ80440.1 - 0.03 14.6 12.7 0.77 10.1 0.2 6.1 6 0 0 6 6 6 0 Galactose oxidase, central domain Reg_prop PF07494.11 KNZ80440.1 - 0.058 13.6 3.5 4 8.0 0.1 5.0 6 0 0 6 6 6 0 Two component regulator propeller PQQ_3 PF13570.6 KNZ80440.1 - 0.47 11.0 7.6 2.1 8.9 0.2 4.8 4 0 0 4 4 4 0 PQQ-like domain zf-C2H2_2 PF12756.7 KNZ80441.1 - 9.9e-34 115.7 8.9 2.9e-31 107.8 0.5 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KNZ80441.1 - 2.4e-07 30.8 2.3 2.4e-07 30.8 2.3 2.8 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ80441.1 - 1.5e-06 28.3 2.0 1.5e-06 28.3 2.0 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KNZ80441.1 - 0.00045 20.8 7.7 0.098 13.5 0.1 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KNZ80441.1 - 0.0032 17.4 1.1 0.15 12.1 0.6 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ80441.1 - 0.086 13.3 11.7 0.13 12.8 0.4 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type CLASP_N PF12348.8 KNZ80442.1 - 1.6e-22 80.2 0.0 2.6e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 KNZ80442.1 - 0.0076 16.4 0.0 1.4 9.4 0.0 3.0 2 0 0 2 2 2 2 HEAT repeat tRNA-synt_2c PF01411.19 KNZ80443.1 - 7.4e-186 618.9 0.3 2.1e-183 610.8 0.3 2.2 1 1 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KNZ80443.1 - 1.9e-17 63.1 0.1 5.2e-17 61.7 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KNZ80443.1 - 1.2e-12 48.4 2.2 1.2e-12 48.4 2.2 2.2 2 0 0 2 2 2 1 DHHA1 domain DUF1664 PF07889.12 KNZ80443.1 - 0.0013 18.8 0.4 0.023 14.7 0.0 2.8 2 1 0 3 3 3 1 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 KNZ80443.1 - 2.3 8.3 5.1 0.96 9.5 1.2 2.2 2 0 0 2 2 2 0 Sperm tail Ribosomal_S13 PF00416.22 KNZ80444.1 - 2.8e-50 170.0 1.1 3.2e-50 169.8 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 KNZ80444.1 - 0.029 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) FbpA PF05833.11 KNZ80444.1 - 0.061 12.1 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) CH PF00307.31 KNZ80444.1 - 0.078 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Calponin homology (CH) domain Mif2_N PF15624.6 KNZ80446.1 - 0.94 10.2 4.4 1.6 9.4 4.4 1.5 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal GNAT_acetyltr_2 PF13718.6 KNZ80447.1 - 4.4e-90 301.0 0.0 8.7e-90 300.1 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KNZ80447.1 - 8.9e-81 271.0 0.0 1.6e-80 270.2 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KNZ80447.1 - 9.7e-64 214.5 0.0 3.2e-63 212.8 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KNZ80447.1 - 2e-32 111.0 0.1 5.4e-32 109.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KNZ80447.1 - 0.0079 15.9 0.0 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain YjeF_N PF03853.15 KNZ80447.1 - 0.0088 15.9 0.1 6.2 6.7 0.0 2.4 2 0 0 2 2 2 2 YjeF-related protein N-terminus AAA_19 PF13245.6 KNZ80447.1 - 0.099 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 KNZ80448.1 - 0.0021 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dickkopf_N PF04706.12 KNZ80449.1 - 0.0011 19.3 6.6 0.0011 19.3 6.6 4.2 4 0 0 4 4 4 2 Dickkopf N-terminal cysteine-rich region EB PF01683.18 KNZ80449.1 - 0.34 11.2 30.9 0.18 12.1 1.3 4.1 3 2 1 4 4 4 0 EB module Integrase_H2C2 PF17921.1 KNZ80452.1 - 7.8e-08 32.3 0.9 7.8e-08 32.3 0.9 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 KNZ80452.1 - 0.03 14.5 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain SH3_9 PF14604.6 KNZ80455.1 - 4.8e-15 55.2 0.1 1e-14 54.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ80455.1 - 1.3e-14 53.5 0.1 3.7e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KNZ80455.1 - 1.5e-12 47.9 0.2 3.8e-12 46.7 0.2 1.7 1 0 0 1 1 1 1 PH domain SAM_2 PF07647.17 KNZ80455.1 - 1.7e-12 47.3 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KNZ80455.1 - 1.5e-09 38.1 0.1 5.6e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KNZ80455.1 - 6.2e-09 35.4 0.0 1.6e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_3 PF18016.1 KNZ80455.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KNZ80455.1 - 0.99 9.9 4.1 7.9 7.0 4.1 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain SGL PF08450.12 KNZ80456.1 - 7.9e-07 28.9 0.1 1.2e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Peptidase_C1_2 PF03051.15 KNZ80457.1 - 1.7e-155 518.1 0.0 2e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KNZ80457.1 - 3e-06 27.5 0.1 0.022 14.8 0.1 2.5 2 1 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.13 KNZ80457.1 - 0.046 12.9 0.0 0.095 11.8 0.0 1.4 2 0 0 2 2 2 0 Phage portal protein, lambda family DnaJ PF00226.31 KNZ80459.1 - 7.6e-12 45.2 0.1 1.5e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain TRP PF06011.12 KNZ80460.1 - 1.8e-72 244.4 31.1 2.8e-72 243.8 31.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KNZ80460.1 - 5.1e-27 94.9 0.3 5.1e-27 94.9 0.3 1.6 2 0 0 2 2 2 1 ML-like domain EphA2_TM PF14575.6 KNZ80460.1 - 3.7 8.5 5.1 29 5.6 0.0 3.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain OSCP PF00213.18 KNZ80461.1 - 7.6e-42 143.3 1.9 8.7e-42 143.2 1.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit PEMT PF04191.13 KNZ80462.1 - 1.5e-12 47.8 1.1 9.3e-12 45.3 0.3 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 KNZ80462.1 - 5.1e-12 46.0 0.6 1.4e-10 41.4 0.1 2.3 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 KNZ80462.1 - 0.00049 19.7 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KNZ80462.1 - 0.003 16.4 0.1 0.0039 16.0 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family MgsA_C PF12002.8 KNZ80463.1 - 1.2e-54 184.7 0.2 3.5e-54 183.2 0.2 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KNZ80463.1 - 1.3e-17 63.9 0.4 3.2e-17 62.6 0.4 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KNZ80463.1 - 4e-08 33.8 0.2 2.1e-07 31.4 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNZ80463.1 - 8.5e-07 28.9 0.0 2.1e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KNZ80463.1 - 0.001 19.1 0.0 0.0027 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KNZ80463.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KNZ80463.1 - 0.025 14.6 0.1 0.11 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KNZ80463.1 - 0.053 13.9 1.1 2.1 8.7 0.1 3.0 2 1 1 3 3 3 0 AAA ATPase domain Peptidase_C15 PF01470.17 KNZ80464.1 - 2.7e-09 37.5 0.0 0.00016 21.9 0.0 2.4 2 0 0 2 2 2 2 Pyroglutamyl peptidase APS_kinase PF01583.20 KNZ80465.1 - 3.9e-69 231.5 0.0 4.6e-69 231.3 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 KNZ80465.1 - 5.8e-05 23.6 0.0 7.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNZ80465.1 - 8.2e-05 22.8 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KNZ80465.1 - 0.0014 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KNZ80465.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KNZ80465.1 - 0.035 13.4 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.12 KNZ80465.1 - 0.16 11.8 0.2 0.37 10.6 0.2 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein G-alpha PF00503.20 KNZ80465.1 - 0.19 10.9 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Pkinase PF00069.25 KNZ80466.1 - 1.2e-42 146.1 0.0 1.5e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80466.1 - 1.4e-34 119.5 0.0 1.9e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ80466.1 - 7.2e-06 25.0 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KNZ80466.1 - 0.077 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KNZ80466.1 - 0.081 12.2 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KNZ80466.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hexapep PF00132.24 KNZ80467.1 - 4.5e-09 35.7 0.7 0.0027 17.4 1.0 3.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KNZ80467.1 - 1.6e-07 31.2 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 KNZ80467.1 - 2.8e-06 27.8 0.0 4.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 KNZ80467.1 - 0.0016 16.6 1.4 0.014 13.5 1.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 KNZ80467.1 - 0.047 12.6 0.9 0.094 11.6 0.9 1.5 1 1 0 1 1 1 0 L-fucokinase Bactofilin PF04519.13 KNZ80467.1 - 0.33 11.3 3.6 0.52 10.6 3.6 1.3 1 0 0 1 1 1 0 Polymer-forming cytoskeletal Hexapep_2 PF14602.6 KNZ80467.1 - 0.39 10.5 3.8 1.6 8.6 1.5 2.3 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase CAP_GLY PF01302.25 KNZ80468.1 - 2.5e-17 62.7 2.6 4.1e-17 61.9 2.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain CtIP_N PF10482.9 KNZ80468.1 - 0.00063 19.8 7.6 0.00063 19.8 7.6 6.7 4 3 0 5 5 5 1 Tumour-suppressor protein CtIP N-terminal domain Spc7 PF08317.11 KNZ80468.1 - 0.21 10.5 87.9 0.038 12.9 21.1 5.3 2 2 3 5 5 5 0 Spc7 kinetochore protein CLIP1_ZNF PF16641.5 KNZ80468.1 - 0.28 11.1 14.7 0.074 12.9 1.6 2.8 3 0 0 3 3 3 0 CLIP1 zinc knuckle zf-CCHC_4 PF14392.6 KNZ80468.1 - 0.99 9.2 6.0 6.1 6.7 0.6 2.5 2 0 0 2 2 2 0 Zinc knuckle SAWADEE PF16719.5 KNZ80468.1 - 1.6 8.7 4.4 15 5.6 0.5 2.9 2 0 0 2 2 2 0 SAWADEE domain zf-CCHC PF00098.23 KNZ80468.1 - 2.1 8.6 10.0 0.63 10.2 2.9 2.3 2 0 0 2 2 2 0 Zinc knuckle Filament PF00038.21 KNZ80468.1 - 5.1 6.6 78.5 0.052 13.1 6.3 4.6 1 1 3 4 4 4 0 Intermediate filament protein eIF-3c_N PF05470.12 KNZ80470.1 - 4.8e-175 583.3 17.6 4.8e-175 583.3 17.6 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 KNZ80470.1 - 1e-15 58.1 0.5 1.6e-14 54.2 0.0 3.0 4 0 0 4 4 4 1 PCI domain DASH_Ask1 PF08655.10 KNZ80470.1 - 0.093 12.6 0.5 7.2 6.6 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Ask1 AHD PF17793.1 KNZ80470.1 - 0.16 11.8 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 ANC1 homology domain (AHD) T7SS_ESX_EspC PF10824.8 KNZ80470.1 - 0.21 12.1 5.3 6.2 7.4 0.0 3.5 4 0 0 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm SYF2 PF08231.12 KNZ80470.1 - 0.3 11.5 4.1 0.62 10.4 2.8 2.1 2 0 0 2 2 2 0 SYF2 splicing factor DUF2408 PF10303.9 KNZ80470.1 - 5.7 7.5 8.2 3.4 8.2 2.3 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF2408) PAP2_3 PF14378.6 KNZ80471.1 - 3.3e-23 82.4 14.7 3.3e-23 82.4 14.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KNZ80471.1 - 1.3e-08 34.7 6.7 1.3e-08 34.7 6.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily ODC_AZ PF02100.17 KNZ80472.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Ribosomal_S5 PF00333.20 KNZ80473.1 - 1.5e-28 98.5 0.8 3.1e-28 97.5 0.8 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KNZ80473.1 - 1.9e-22 78.5 0.1 3.4e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Peptidase_S68 PF10461.9 KNZ80473.1 - 0.052 13.8 0.1 0.15 12.2 0.1 1.8 1 0 0 1 1 1 0 Peptidase S68 p450 PF00067.22 KNZ80474.1 - 4.6e-64 216.9 0.0 1.7e-63 215.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF3419 PF11899.8 KNZ80476.1 - 1.4e-140 468.9 0.0 1.7e-140 468.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 KNZ80476.1 - 0.00067 20.3 0.0 0.012 16.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ80476.1 - 0.0065 16.3 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ80476.1 - 0.0094 16.6 0.0 1.3 9.7 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ80476.1 - 0.01 15.2 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KNZ80476.1 - 0.14 12.9 0.0 14 6.5 0.0 3.4 4 1 1 5 5 5 0 Methyltransferase domain KTI12 PF08433.10 KNZ80477.1 - 3e-78 263.0 0.0 3.4e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KNZ80477.1 - 4.5e-07 30.1 0.0 2.4e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KNZ80477.1 - 0.087 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.27 KNZ80478.1 - 2.4e-41 141.1 0.0 1.1e-40 139.0 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 KNZ80478.1 - 5.2e-14 52.2 15.4 9.8e-07 28.9 7.0 2.7 2 0 0 2 2 2 2 LIM domain C1_1 PF00130.22 KNZ80478.1 - 6.5e-06 25.9 7.8 6.5e-06 25.9 7.8 3.7 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 KNZ80478.1 - 0.021 15.1 1.5 0.021 15.1 1.5 4.0 2 1 1 3 3 3 0 C1 domain DUF3797 PF12677.7 KNZ80478.1 - 0.22 11.4 3.1 2.6 8.0 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) BTB PF00651.31 KNZ80479.1 - 1.2e-11 44.8 0.0 0.00027 21.1 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain RPA43_OB PF17875.1 KNZ80480.1 - 1.8e-24 86.7 0.0 1.8e-24 86.7 0.0 2.6 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SID-1_RNA_chan PF13965.6 KNZ80480.1 - 0.36 9.2 0.2 0.46 8.8 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pam16 PF03656.13 KNZ80481.1 - 6.3e-20 71.5 0.7 4.8e-19 68.6 0.7 2.0 1 1 0 1 1 1 1 Pam16 Nup96 PF12110.8 KNZ80481.1 - 0.23 10.5 0.3 0.73 8.9 0.2 1.7 1 1 1 2 2 2 0 Nuclear protein 96 PALP PF00291.25 KNZ80482.1 - 1.3e-67 228.3 0.4 1.6e-67 228.0 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.21 KNZ80483.1 - 4.9e-77 257.3 0.0 5.6e-77 257.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KNZ80483.1 - 6.2e-15 55.5 0.0 8.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KNZ80483.1 - 8.6e-13 48.2 0.0 9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KNZ80483.1 - 5.9e-11 42.1 1.1 1.4e-06 27.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KNZ80483.1 - 1.4e-10 40.9 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KNZ80483.1 - 2.6e-09 36.8 0.0 3.3e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ80483.1 - 0.00037 20.5 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KNZ80483.1 - 0.018 14.4 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PLA2_B PF01735.18 KNZ80484.1 - 5.6e-98 328.5 0.0 7.3e-98 328.1 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TrbC PF04956.13 KNZ80484.1 - 0.066 13.4 0.1 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family LapA_dom PF06305.11 KNZ80484.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 KNZ80484.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4381 PF14316.6 KNZ80484.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SKG6 PF08693.10 KNZ80484.1 - 0.47 9.9 1.6 0.87 9.1 1.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain UBA PF00627.31 KNZ80485.1 - 2.7e-28 97.4 5.7 7.4e-14 51.3 0.9 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 KNZ80485.1 - 7.2e-22 76.9 2.3 1.2e-21 76.2 2.3 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 KNZ80485.1 - 3e-12 46.1 7.0 5.3e-12 45.3 7.0 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 KNZ80485.1 - 1.3e-08 34.5 3.7 2.7e-08 33.5 3.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KNZ80485.1 - 0.0033 17.7 0.6 0.0066 16.8 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KNZ80485.1 - 0.0055 16.8 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 KNZ80485.1 - 0.0065 16.5 2.1 0.12 12.4 0.7 2.4 1 1 1 2 2 2 1 Ubiquitin-like domain UBA_3 PF09288.10 KNZ80485.1 - 0.01 15.6 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain WIYLD PF10440.9 KNZ80485.1 - 0.014 15.2 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF2407 PF10302.9 KNZ80485.1 - 0.028 15.0 0.0 0.058 14.0 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CUE PF02845.16 KNZ80485.1 - 0.036 13.8 0.0 0.33 10.7 0.0 2.4 2 0 0 2 2 2 0 CUE domain DUF1421 PF07223.11 KNZ80485.1 - 0.096 12.5 0.0 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 UBA-like domain (DUF1421) RRM_1 PF00076.22 KNZ80486.1 - 5.1e-15 55.1 0.0 8e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 KNZ80486.1 - 0.017 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 RL domain RRM_5 PF13893.6 KNZ80486.1 - 0.029 14.0 0.0 0.058 13.0 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.6 KNZ80487.1 - 4.8e-12 45.5 11.9 1.2e-08 34.6 3.9 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KNZ80487.1 - 5.4e-12 45.7 13.8 4.4e-05 23.8 1.9 5.5 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KNZ80487.1 - 0.00011 21.7 0.2 0.1 12.1 0.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 KNZ80487.1 - 1.1 10.0 12.8 6.4 7.7 0.1 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat EPL1 PF10513.9 KNZ80488.1 - 9.9e-21 74.8 1.1 1.7e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like SHIPPO-rpt PF07004.12 KNZ80489.1 - 0.0024 18.7 0.2 5.3 8.1 0.0 2.6 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat HMMR_C PF15908.5 KNZ80489.1 - 0.0046 17.2 4.1 0.0046 17.2 4.1 4.5 2 1 0 3 3 3 2 Hyaluronan mediated motility receptor C-terminal Tup_N PF08581.10 KNZ80489.1 - 0.0098 16.2 0.6 0.0098 16.2 0.6 6.3 6 2 2 8 8 8 1 Tup N-terminal ParB_C PF18064.1 KNZ80489.1 - 0.089 13.0 0.6 0.7 10.1 0.0 2.9 4 0 0 4 4 4 0 Centromere-binding protein ParB C-terminal MAD PF05557.13 KNZ80489.1 - 1.7 6.9 58.5 2.7 6.3 58.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein YojJ PF10372.9 KNZ80489.1 - 3.9 7.6 11.2 0.15 12.2 0.3 3.9 4 1 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus NIF PF03031.18 KNZ80490.1 - 9e-55 184.7 0.3 1.2e-54 184.3 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KNZ80490.1 - 0.2 12.1 0.0 1 9.7 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1043 PF06295.12 KNZ80491.1 - 0.026 14.5 1.3 0.22 11.5 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) CD20 PF04103.15 KNZ80491.1 - 0.14 12.2 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 CD20-like family Borrelia_P83 PF05262.11 KNZ80491.1 - 4.3 5.7 16.5 6.1 5.2 16.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Laminin_II PF06009.12 KNZ80491.1 - 4.7 7.2 14.8 5.3 7.1 3.0 2.4 1 1 1 2 2 2 0 Laminin Domain II AAA_23 PF13476.6 KNZ80491.1 - 8.1 6.9 12.9 15 6.0 12.9 1.4 1 0 0 1 1 1 0 AAA domain TPP1 PF10341.9 KNZ80492.1 - 9.8e-05 22.3 0.0 0.00025 21.0 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD bZIP_1 PF00170.21 KNZ80493.1 - 0.0066 16.5 4.0 0.0066 16.5 4.0 3.6 3 1 1 4 4 4 1 bZIP transcription factor FIVAR PF07554.13 KNZ80493.1 - 0.1 13.4 1.1 0.21 12.4 0.3 1.8 2 0 0 2 2 2 0 FIVAR domain ABC_tran_CTD PF16326.5 KNZ80493.1 - 0.2 11.9 3.8 2.3 8.5 2.2 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain T3SSipB PF16535.5 KNZ80493.1 - 1.1 9.8 11.0 0.21 12.0 7.1 1.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF4110 PF13422.6 KNZ80493.1 - 3.9 7.6 7.0 0.18 11.9 0.6 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4110) Jnk-SapK_ap_N PF09744.9 KNZ80493.1 - 5.3 7.2 8.3 1.6 9.0 5.2 1.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 NIF PF03031.18 KNZ80494.1 - 4e-55 185.9 0.1 5.2e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 KNZ80494.1 - 0.016 15.6 0.2 0.095 13.1 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PTPLA PF04387.14 KNZ80495.1 - 2.6e-45 154.1 7.2 4.6e-45 153.3 7.2 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA HHH_5 PF14520.6 KNZ80496.1 - 0.15 12.7 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Pertus-S4-tox PF09275.10 KNZ80496.1 - 0.16 12.2 0.0 0.46 10.8 0.0 1.8 2 0 0 2 2 2 0 Pertussis toxin S4 subunit Gpr1_Fun34_YaaH PF01184.19 KNZ80497.1 - 3.5e-55 186.8 12.7 3.8e-55 186.7 12.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Caps_synth_CapC PF14102.6 KNZ80497.1 - 0.067 13.6 6.6 0.045 14.2 4.8 1.5 1 1 0 1 1 1 0 Capsule biosynthesis CapC ArAE_1 PF06081.11 KNZ80497.1 - 0.068 13.3 4.0 0.083 13.0 3.7 1.4 1 1 0 1 1 1 0 Aromatic acid exporter family member 1 DUF2157 PF09925.9 KNZ80497.1 - 8.3 6.2 13.8 65 3.3 13.8 2.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) His_Phos_2 PF00328.22 KNZ80498.1 - 6.2e-48 164.1 0.0 7.7e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 KNZ80499.1 - 9.9e-66 221.8 0.0 2.4e-65 220.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80499.1 - 3.4e-36 124.9 0.0 4.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ80499.1 - 8.8e-07 28.5 0.0 1.7e-06 27.6 0.0 1.4 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 KNZ80499.1 - 0.045 13.3 0.0 0.53 9.9 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 KNZ80499.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KNZ80499.1 - 0.091 12.4 0.1 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KNZ80499.1 - 0.1 12.5 0.6 15 5.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ80499.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Med25_VWA PF11265.8 KNZ80500.1 - 7.1e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A TFIIA PF03153.13 KNZ80500.1 - 0.079 12.9 43.7 0.087 12.8 11.8 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HlyD_2 PF12700.7 KNZ80500.1 - 0.45 9.2 1.1 0.7 8.6 1.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein SH3_1 PF00018.28 KNZ80501.1 - 8.2e-11 41.3 0.2 1.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ80501.1 - 8.5e-11 41.6 0.1 1.4e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ80501.1 - 8.8e-10 38.1 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Adeno_E3_CR2 PF02439.15 KNZ80502.1 - 0.038 13.7 0.5 0.076 12.8 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 KNZ80502.1 - 0.039 14.2 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A PTP_tm PF18861.1 KNZ80502.1 - 0.13 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Podoplanin PF05808.11 KNZ80502.1 - 0.16 12.0 0.1 0.28 11.3 0.1 1.3 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.6 KNZ80502.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family FixQ PF05545.11 KNZ80502.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Glyco_hydro_16 PF00722.21 KNZ80503.1 - 6.8e-05 22.4 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CMD PF02627.20 KNZ80503.1 - 0.00077 19.5 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Rad21_Rec8_N PF04825.13 KNZ80504.1 - 9.3e-25 86.9 0.3 1.7e-24 86.1 0.3 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KNZ80504.1 - 2.8e-14 52.1 0.0 4.8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein PBP_N PF17093.5 KNZ80504.1 - 0.033 14.5 1.3 0.15 12.3 1.2 2.1 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus PRIMA1 PF16101.5 KNZ80504.1 - 0.64 10.1 2.9 1.3 9.1 2.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PPR_2 PF13041.6 KNZ80505.1 - 1.1e-34 118.3 3.3 2.2e-06 27.8 0.0 9.2 6 4 4 10 10 10 7 PPR repeat family PPR_3 PF13812.6 KNZ80505.1 - 4.9e-29 100.2 2.3 8.9e-09 35.3 0.0 5.9 6 1 0 6 6 6 5 Pentatricopeptide repeat domain PPR_long PF17177.4 KNZ80505.1 - 3.4e-24 85.4 0.2 6.4e-09 35.5 0.0 4.5 1 1 5 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KNZ80505.1 - 3.4e-17 61.4 2.4 0.021 15.1 0.0 10.0 12 0 0 12 12 12 3 PPR repeat PPR_1 PF12854.7 KNZ80505.1 - 1.1e-11 44.2 0.8 0.0012 18.5 0.0 6.9 8 0 0 8 8 8 3 PPR repeat ECSIT PF06239.11 KNZ80505.1 - 0.00017 20.8 2.3 17 4.5 0.0 6.5 5 1 1 7 7 7 1 Evolutionarily conserved signalling intermediate in Toll pathway Wzy_C_2 PF11846.8 KNZ80505.1 - 0.014 15.3 0.0 9.4 6.1 0.0 3.0 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal HrpB1_HrpK PF09613.10 KNZ80505.1 - 0.016 14.8 2.2 2.6 7.7 0.1 3.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) RabGAP-TBC PF00566.18 KNZ80505.1 - 0.038 13.7 0.9 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Rab-GTPase-TBC domain DUF960 PF06124.11 KNZ80505.1 - 0.048 14.3 2.1 2.3 8.9 0.1 2.9 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) p450 PF00067.22 KNZ80506.1 - 1.2e-57 195.7 0.0 1.6e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FUSC_2 PF13515.6 KNZ80507.1 - 2.9e-18 66.2 10.5 2.9e-18 66.2 10.5 3.0 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 KNZ80507.1 - 4.8e-09 35.6 9.5 4.1e-08 32.5 6.0 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 KNZ80507.1 - 5.8e-09 36.1 0.4 1.3e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 KNZ80507.1 - 8.2e-08 31.3 12.4 1.1e-07 30.8 5.0 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein family FUSC-like PF12805.7 KNZ80507.1 - 0.13 11.3 4.7 1.3 8.0 2.6 2.4 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Pkinase PF00069.25 KNZ80508.1 - 6.3e-47 160.1 0.0 5.6e-38 130.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80508.1 - 2.3e-19 69.7 0.0 5e-19 68.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ80508.1 - 3.1e-05 23.5 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ80508.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ80508.1 - 0.044 12.5 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KNZ80508.1 - 0.053 12.9 0.1 0.079 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KNZ80508.1 - 0.094 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HhH-GPD PF00730.25 KNZ80510.1 - 1e-12 48.4 0.0 2.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Inhibitor_I9 PF05922.16 KNZ80511.1 - 1.3e-06 28.9 0.6 3e-06 27.8 0.6 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 KNZ80511.1 - 0.0082 16.0 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 DAHP synthase ferredoxin-like domain HisK_N PF09385.10 KNZ80511.1 - 0.023 14.6 0.0 0.025 14.6 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase N terminal Sigma70_r1_1 PF03979.14 KNZ80511.1 - 0.036 14.1 0.2 9.8 6.3 0.0 2.1 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 UPF0113 PF03657.13 KNZ80511.1 - 0.047 14.0 0.1 0.056 13.7 0.1 1.1 1 0 0 1 1 1 0 UPF0113 PUA domain Tape_meas_lam_C PF09718.10 KNZ80511.1 - 0.071 13.3 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SLAC1 PF03595.17 KNZ80513.1 - 7.1e-62 209.5 37.7 8e-62 209.4 37.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SDA1 PF05285.12 KNZ80515.1 - 0.0012 18.4 10.8 0.0012 18.4 10.8 2.9 2 1 0 2 2 2 1 SDA1 BUD22 PF09073.10 KNZ80515.1 - 0.0028 17.1 10.0 0.0028 17.1 10.0 2.6 2 1 0 2 2 2 1 BUD22 Serinc PF03348.15 KNZ80515.1 - 0.33 9.8 1.8 0.91 8.4 0.2 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) RP-C_C PF11800.8 KNZ80515.1 - 2.4 8.2 8.4 0.16 12.0 1.0 2.6 2 1 0 2 2 2 0 Replication protein C C-terminal region Lactamase_B PF00753.27 KNZ80516.1 - 9.2e-14 51.9 0.6 2.4e-13 50.5 0.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KNZ80516.1 - 0.0072 15.9 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SLAC1 PF03595.17 KNZ80517.1 - 2.4e-59 201.2 48.4 3e-59 200.9 48.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Glyco_hydro_76 PF03663.14 KNZ80518.1 - 1.1e-36 127.2 19.1 1.2e-36 127.0 19.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cu-oxidase_3 PF07732.15 KNZ80518.1 - 0.13 12.2 1.2 1 9.4 0.2 2.2 2 0 0 2 2 2 0 Multicopper oxidase PH_9 PF15410.6 KNZ80519.1 - 6.9e-29 100.6 0.0 2e-28 99.1 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Sec7 PF01369.20 KNZ80519.1 - 1.1e-28 100.1 0.1 2.9e-28 98.8 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain GATA PF00320.27 KNZ80519.1 - 5.3e-18 64.3 2.0 1.2e-17 63.2 2.0 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 KNZ80519.1 - 1.5e-11 43.9 1.0 3.6e-11 42.7 1.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PH PF00169.29 KNZ80519.1 - 0.0011 19.5 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Peptidase_A22B PF04258.13 KNZ80520.1 - 1e-72 245.1 3.3 1.4e-72 244.7 3.3 1.0 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KNZ80520.1 - 4.2e-05 23.2 8.8 4.7e-05 23.0 6.5 2.1 1 1 1 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease CrgA PF06781.12 KNZ80520.1 - 0.024 14.7 0.1 0.07 13.2 0.1 1.9 1 0 0 1 1 1 0 Cell division protein CrgA G_glu_transpept PF01019.21 KNZ80521.1 - 5.8e-151 503.7 0.0 6.5e-151 503.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.25 KNZ80525.1 - 6.2e-69 232.3 0.0 7.8e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80525.1 - 5.8e-37 127.4 0.0 1.1e-36 126.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 KNZ80525.1 - 5.4e-16 58.7 0.2 1.2e-15 57.6 0.2 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KNZ80525.1 - 2.4e-05 23.8 0.0 6.6e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ80525.1 - 0.0048 16.9 0.0 0.061 13.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KNZ80525.1 - 0.0079 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FHA_2 PF17913.1 KNZ80525.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 FHA domain DUF3460 PF11943.8 KNZ80525.1 - 0.052 13.8 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3460) RIO1 PF01163.22 KNZ80525.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 1 0 1 1 1 0 RIO1 family RRM_1 PF00076.22 KNZ80526.1 - 1.2e-13 50.7 0.4 6.3e-06 25.9 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KNZ80526.1 - 0.041 14.0 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM PF05172.13 KNZ80526.1 - 0.13 12.2 0.0 0.84 9.6 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Acyltransferase PF01553.21 KNZ80527.1 - 1.5e-17 63.5 0.0 2.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase SNARE_assoc PF09335.11 KNZ80527.1 - 0.011 16.2 0.7 0.025 15.1 0.7 1.6 1 0 0 1 1 1 0 SNARE associated Golgi protein HIP1_clath_bdg PF16515.5 KNZ80528.1 - 0.039 14.6 4.7 0.1 13.2 3.5 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 KNZ80528.1 - 0.046 13.3 3.0 0.064 12.8 3.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DED PF01335.21 KNZ80528.1 - 0.21 11.9 1.5 3.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Death effector domain SPC22 PF04573.12 KNZ80529.1 - 3.7e-51 173.0 0.3 4.5e-51 172.7 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Pkinase PF00069.25 KNZ80531.1 - 5.7e-69 232.4 0.0 7.5e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80531.1 - 1.1e-38 133.0 0.0 1.5e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KNZ80531.1 - 1.2e-17 64.0 0.1 3e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 KNZ80531.1 - 2.3e-06 27.1 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 KNZ80531.1 - 3.4e-06 27.3 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 KNZ80531.1 - 9.7e-05 21.8 0.0 0.00024 20.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 KNZ80531.1 - 0.0053 16.7 0.0 0.38 10.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KNZ80531.1 - 0.056 12.4 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KNZ80531.1 - 0.087 11.6 0.1 0.26 10.0 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase S-methyl_trans PF02574.16 KNZ80532.1 - 6.2e-39 134.4 0.0 1e-38 133.7 0.0 1.3 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Cytochrom_B561 PF03188.16 KNZ80533.1 - 4.7e-11 43.0 4.4 4.7e-11 43.0 4.4 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 KNZ80533.1 - 1.5e-08 34.5 0.4 7.2e-07 29.1 0.3 3.0 2 1 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DUF3382 PF11862.8 KNZ80533.1 - 0.039 14.2 0.3 0.17 12.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3382) MRAP PF15183.6 KNZ80533.1 - 0.17 11.8 1.3 0.3 11.0 0.2 2.0 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family API5 PF05918.11 KNZ80534.1 - 4.5e-16 58.8 2.8 5.6e-16 58.4 2.8 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) Cnd1 PF12717.7 KNZ80534.1 - 6.6e-05 23.0 1.8 0.00018 21.6 0.3 2.2 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KNZ80534.1 - 0.0029 18.0 0.3 0.013 15.9 0.0 2.3 3 0 0 3 3 3 1 HEAT repeats Oxidored_q6 PF01058.22 KNZ80535.1 - 2.3e-22 79.2 0.1 3.4e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit SoxG PF04268.12 KNZ80535.1 - 0.06 13.5 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family Mnd1 PF03962.15 KNZ80537.1 - 5.9e-24 84.1 0.2 1.2e-23 83.1 0.2 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 KNZ80537.1 - 2.5e-09 37.1 0.1 5e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FlxA PF14282.6 KNZ80537.1 - 0.069 13.1 0.0 0.069 13.1 0.0 2.2 1 1 1 2 2 2 0 FlxA-like protein ABC_tran_Xtn PF12848.7 KNZ80537.1 - 4.8 7.3 8.8 1.7 8.7 5.6 1.9 2 0 0 2 2 2 0 ABC transporter Zn_clus PF00172.18 KNZ80539.1 - 3.6e-08 33.4 11.9 6.4e-08 32.6 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNZ80539.1 - 2.3e-07 30.1 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain W2 PF02020.18 KNZ80540.1 - 4.6e-19 68.3 1.8 7.6e-19 67.6 0.1 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon TetR PF13972.6 KNZ80540.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial transcriptional repressor PP2C PF00481.21 KNZ80541.1 - 6.1e-56 189.9 0.1 4.1e-46 157.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C UPF0154 PF03672.13 KNZ80541.1 - 0.21 11.6 0.1 0.39 10.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) PP2C PF00481.21 KNZ80542.1 - 1.5e-66 224.7 0.1 2.6e-52 178.0 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 KNZ80542.1 - 3.4e-05 23.9 0.2 0.012 15.5 0.1 2.9 2 1 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Choline_transpo PF04515.12 KNZ80543.1 - 3.3e-75 253.3 19.5 3.3e-75 253.3 19.5 2.9 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF2628 PF10947.8 KNZ80544.1 - 0.064 13.6 1.5 5 7.5 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Amastin PF07344.11 KNZ80544.1 - 0.12 12.2 6.9 0.036 13.9 2.7 2.0 2 1 0 2 2 2 0 Amastin surface glycoprotein Clc-like PF07062.12 KNZ80544.1 - 0.15 11.5 2.3 0.37 10.2 2.3 1.7 1 1 0 1 1 1 0 Clc-like zf-RING_2 PF13639.6 KNZ80545.1 - 6.6e-10 39.2 1.5 2.8e-08 33.9 0.3 2.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 KNZ80545.1 - 1.7e-07 31.4 1.5 9.1e-07 29.1 0.3 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 KNZ80545.1 - 3.6e-07 29.9 0.7 3.6e-07 29.9 0.7 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KNZ80545.1 - 2.4e-06 27.2 2.4 0.00041 20.0 0.0 3.1 3 0 0 3 3 3 2 RING-like zinc finger zf-RING_5 PF14634.6 KNZ80545.1 - 8.1e-06 25.7 1.1 7.6e-05 22.6 0.1 2.8 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KNZ80545.1 - 1.6e-05 24.7 1.8 1.8e-05 24.5 0.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KNZ80545.1 - 2.3e-05 24.3 4.4 0.00082 19.3 0.0 3.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KNZ80545.1 - 2.7e-05 24.0 3.5 0.0001 22.1 0.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KNZ80545.1 - 0.0023 17.9 0.5 0.0051 16.8 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KNZ80545.1 - 0.0026 17.3 0.4 0.0026 17.3 0.4 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 KNZ80545.1 - 0.031 14.1 2.2 0.066 13.1 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNZ80545.1 - 0.14 12.3 2.2 0.16 12.1 0.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KNZ80545.1 - 0.25 11.5 5.1 1.8 8.8 3.1 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 KNZ80545.1 - 3 8.0 4.7 0.78 9.9 0.9 2.0 2 0 0 2 2 2 0 RING-variant domain GTP_EFTU PF00009.27 KNZ80547.1 - 7.3e-19 68.1 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KNZ80547.1 - 2.3e-06 27.9 0.5 4.7e-05 23.7 0.1 3.4 4 0 0 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 KNZ80547.1 - 7e-05 23.1 0.0 0.00016 21.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KNZ80547.1 - 0.079 13.1 0.1 0.27 11.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase SKN1 PF03935.15 KNZ80548.1 - 1.3e-183 611.1 4.8 1.5e-183 610.8 4.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_18 PF00704.28 KNZ80549.1 - 7.3e-86 288.7 1.1 1.1e-85 288.1 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_1 PF00734.18 KNZ80550.1 - 2.9e-11 43.1 12.1 6.5e-11 42.0 12.1 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain SNARE PF05739.19 KNZ80551.1 - 2.2e-05 24.3 0.7 5e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 SNARE domain SLD3 PF08639.10 KNZ80551.1 - 0.00093 18.1 0.2 0.0013 17.6 0.2 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 Syntaxin PF00804.25 KNZ80551.1 - 0.0073 16.0 0.8 0.024 14.3 0.8 1.9 1 1 0 1 1 1 1 Syntaxin POTRA_2 PF08479.11 KNZ80551.1 - 0.053 13.4 0.6 11 6.0 0.1 3.4 3 1 0 3 3 3 0 POTRA domain, ShlB-type Fe_hyd_lg_C PF02906.14 KNZ80553.1 - 7.7e-61 205.9 0.0 1.6e-60 204.8 0.0 1.5 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ferrochelatase PF00762.19 KNZ80554.1 - 1.2e-97 326.9 0.0 1.3e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase UNC-79 PF14776.6 KNZ80554.1 - 0.074 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 GHMP_kinases_N PF00288.26 KNZ80555.1 - 1.2e-12 47.9 3.7 2.4e-12 46.9 3.7 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KNZ80555.1 - 0.00019 21.7 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.18 KNZ80556.1 - 3.4e-73 246.7 31.1 3.9e-73 246.5 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2574 PF10836.8 KNZ80556.1 - 0.0047 16.8 1.4 1.4 8.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2574) Trp_Tyr_perm PF03222.13 KNZ80556.1 - 0.048 12.7 25.5 0.085 11.9 21.2 2.4 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family MS_channel PF00924.18 KNZ80559.1 - 1.8e-23 83.2 0.9 1.8e-23 83.2 0.9 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KNZ80559.1 - 0.008 15.6 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KNZ80559.1 - 0.0095 15.8 0.1 0.03 14.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 KNZ80559.1 - 0.012 15.1 0.3 0.031 13.8 0.3 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 KNZ80559.1 - 0.098 13.1 0.3 0.32 11.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 KNZ80559.1 - 0.14 12.0 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair RNA_pol_A_bac PF01000.26 KNZ80560.1 - 2.4e-27 95.5 0.0 4.2e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KNZ80560.1 - 3.3e-19 68.1 0.0 4.5e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CSL PF05207.13 KNZ80560.1 - 0.023 14.4 0.9 0.047 13.4 0.9 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF22 PF01629.16 KNZ80560.1 - 0.23 11.2 0.4 0.46 10.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF22 Alpha-2-MRAP_N PF06400.11 KNZ80564.1 - 0.33 11.0 3.8 0.12 12.4 0.8 1.7 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain gag-asp_proteas PF13975.6 KNZ80565.1 - 5.1e-05 23.8 0.1 9.8e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80565.1 - 0.056 14.1 0.1 0.09 13.4 0.0 1.4 2 0 0 2 2 2 0 Aspartyl protease Asp_protease PF09668.10 KNZ80565.1 - 0.073 12.9 0.1 0.24 11.2 0.0 1.8 1 1 1 2 2 2 0 Aspartyl protease UCH PF00443.29 KNZ80567.1 - 2.7e-27 95.9 0.0 4e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KNZ80567.1 - 7e-11 42.3 0.1 1.3e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KNZ80567.1 - 0.28 11.0 0.9 0.73 9.6 0.9 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger Rsm22 PF09243.10 KNZ80568.1 - 9.7e-44 149.7 0.0 7.7e-41 140.2 0.0 3.1 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.21 KNZ80569.1 - 4.9e-21 75.4 0.0 7.2e-21 74.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.9 KNZ80570.1 - 1.8e-10 41.2 5.5 9.1e-10 38.9 2.5 2.3 1 1 0 2 2 2 1 Mitochondrial ribosomal protein L28 Peptidase_M85 PF13678.6 KNZ80570.1 - 0.13 11.8 0.2 0.21 11.2 0.2 1.3 1 0 0 1 1 1 0 NFkB-p65-degrading zinc protease PCI PF01399.27 KNZ80571.1 - 1.4e-18 67.3 0.3 3.9e-18 65.9 0.3 1.8 1 0 0 1 1 1 1 PCI domain DUF5517 PF17639.2 KNZ80571.1 - 0.05 13.9 5.5 0.46 10.8 0.4 3.4 3 1 0 3 3 3 0 Family of unknown function (DUF5517) PIP5K PF01504.18 KNZ80572.1 - 1.5e-45 155.6 0.3 1e-36 126.6 0.1 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 KNZ80572.1 - 6.5e-27 94.3 0.0 9.9e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KNZ80572.1 - 6.4e-17 61.5 13.9 1.3e-16 60.5 12.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 KNZ80572.1 - 0.53 10.6 11.3 0.068 13.4 6.5 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Ribosomal_S27e PF01667.17 KNZ80572.1 - 1.7 8.4 4.0 4.1 7.2 4.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 Bromodomain PF00439.25 KNZ80573.1 - 1.8e-50 169.0 0.0 7.2e-19 67.7 0.1 3.5 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.20 KNZ80573.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 KNZ80573.1 - 0.005 17.2 0.3 4.4 7.8 0.1 3.2 2 0 0 2 2 2 2 HEAT repeats Peptidase_M1_N PF17900.1 KNZ80573.1 - 0.014 15.6 0.5 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain LTV PF04180.14 KNZ80574.1 - 2.3e-97 327.2 13.1 2.2e-90 304.2 10.9 2.1 1 1 1 2 2 2 2 Low temperature viability protein Het-C PF07217.11 KNZ80575.1 - 3.3e-202 673.0 0.0 4.6e-202 672.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Med11 PF10280.9 KNZ80576.1 - 9.6e-11 42.3 0.1 1.2e-10 42.0 0.1 1.3 1 1 0 1 1 1 1 Mediator complex protein TBCA PF02970.16 KNZ80577.1 - 2.2e-18 66.4 4.2 2.6e-18 66.1 3.4 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A HLH PF00010.26 KNZ80578.1 - 1.7e-10 40.7 3.2 4.2e-10 39.4 3.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF641 PF04859.12 KNZ80578.1 - 0.23 11.8 3.2 0.35 11.2 3.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Uso1_p115_C PF04871.13 KNZ80578.1 - 0.27 11.6 3.3 0.45 10.9 3.3 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 KNZ80578.1 - 0.8 10.2 5.1 1.5 9.4 5.1 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 KNZ80578.1 - 0.8 8.2 1.5 1 7.9 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HLH PF00010.26 KNZ80579.1 - 2.8e-10 40.0 1.9 2.8e-10 40.0 1.9 2.3 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain FapA PF03961.13 KNZ80579.1 - 0.023 13.3 0.8 0.031 12.9 0.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_C21 PF05381.12 KNZ80579.1 - 0.074 13.4 0.1 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 Tymovirus endopeptidase Chitin_synth_1 PF01644.17 KNZ80581.1 - 1.9e-71 239.3 0.1 2.9e-71 238.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KNZ80581.1 - 3.5e-27 94.2 0.0 1.2e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KNZ80581.1 - 2.2e-21 76.1 0.6 4.8e-16 58.5 0.0 2.5 2 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KNZ80581.1 - 0.0013 18.6 6.8 0.0092 15.9 6.8 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 PLDc_N PF13396.6 KNZ80581.1 - 8.7 6.4 7.8 12 6.0 0.2 3.7 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal Pkinase PF00069.25 KNZ80582.1 - 2.8e-26 92.5 0.0 3.6e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80582.1 - 1.9e-13 50.3 0.0 2.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ80582.1 - 3.2e-09 36.1 0.8 3.5e-09 35.9 0.1 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KNZ80582.1 - 0.001 19.1 0.3 0.0076 16.2 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KNZ80582.1 - 0.023 13.7 0.1 0.033 13.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KNZ80582.1 - 0.074 12.4 0.6 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adaptin_N PF01602.20 KNZ80583.1 - 8.9e-114 380.9 0.1 4.1e-113 378.7 0.1 1.9 1 1 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KNZ80583.1 - 1.7e-50 171.1 4.3 2.3e-50 170.7 2.7 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KNZ80583.1 - 1.8e-34 118.3 0.0 4.4e-34 117.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KNZ80583.1 - 3.6e-20 72.2 3.6 1.2e-09 38.4 0.0 6.1 2 2 3 6 6 6 4 HEAT repeats Cnd1 PF12717.7 KNZ80583.1 - 5e-07 29.9 6.4 0.01 15.9 0.1 4.2 4 1 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KNZ80583.1 - 0.0017 18.5 9.0 6 7.4 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat DUF3385 PF11865.8 KNZ80583.1 - 0.1 12.5 0.4 1.6 8.7 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 KNZ80583.1 - 0.22 12.3 4.1 16 6.5 0.1 5.6 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat PIF1 PF05970.14 KNZ80584.1 - 5.7e-31 108.0 0.2 1.3e-30 106.8 0.2 1.6 1 1 0 1 1 1 1 PIF1-like helicase Fumble PF03630.14 KNZ80585.1 - 1.5e-128 428.7 0.0 1.9e-128 428.3 0.0 1.1 1 0 0 1 1 1 1 Fumble Homeodomain PF00046.29 KNZ80586.1 - 4e-46 154.7 10.0 5.2e-17 61.4 0.4 3.4 3 0 0 3 3 3 3 Homeodomain Homeobox_KN PF05920.11 KNZ80586.1 - 5.8e-13 48.5 2.3 0.00033 20.5 0.4 3.6 3 0 0 3 3 3 3 Homeobox KN domain YdaS_antitoxin PF15943.5 KNZ80586.1 - 4.2e-07 29.7 0.1 0.04 13.8 0.0 3.3 3 0 0 3 3 3 3 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT HOCHOB PF17943.1 KNZ80586.1 - 1.7e-06 28.8 0.0 0.97 10.2 0.0 3.3 3 0 0 3 3 3 3 Homeobox-cysteine loop-homeobox HTH_3 PF01381.22 KNZ80586.1 - 0.00016 21.6 0.3 0.64 10.1 0.0 3.4 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.8 KNZ80586.1 - 0.098 12.1 1.1 20 4.7 0.1 3.2 3 0 0 3 3 3 0 Homeodomain leucine-zipper encoding, Homez Phage_CI_repr PF07022.13 KNZ80586.1 - 0.16 12.1 0.1 13 6.0 0.1 2.7 3 0 0 3 3 3 0 Bacteriophage CI repressor helix-turn-helix domain HTH_OrfB_IS605 PF12323.8 KNZ80586.1 - 0.18 11.3 0.3 10 5.7 0.1 2.5 1 1 1 2 2 2 0 Helix-turn-helix domain Auxin_canalis PF05703.11 KNZ80586.1 - 0.36 10.7 11.6 5.8 6.8 1.3 3.4 2 1 0 3 3 3 0 Auxin canalisation Senescence_reg PF04520.13 KNZ80586.1 - 6.2 7.6 18.9 0.52 11.1 0.6 3.5 2 1 1 3 3 3 0 Senescence regulator polyprenyl_synt PF00348.17 KNZ80587.1 - 2.8e-18 65.9 0.0 6.9e-18 64.6 0.0 1.6 2 0 0 2 2 2 1 Polyprenyl synthetase DUF543 PF04418.12 KNZ80587.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) TM1506 PF08973.10 KNZ80587.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) HEPPP_synt_1 PF07307.11 KNZ80587.1 - 0.053 13.1 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 RRM_1 PF00076.22 KNZ80588.1 - 6.1e-10 38.8 0.1 7.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KNZ80588.1 - 0.034 14.2 0.1 2 8.5 0.1 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ras PF00071.22 KNZ80589.1 - 1.2e-59 200.5 0.1 1.4e-59 200.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ80589.1 - 1.3e-36 125.4 0.0 1.8e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ80589.1 - 1.8e-14 53.5 0.1 2.2e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ80589.1 - 2.7e-06 27.4 0.0 4.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ80589.1 - 4.8e-06 26.6 0.2 0.038 13.9 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KNZ80589.1 - 8.7e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KNZ80589.1 - 2.8e-05 23.6 0.0 3.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 KNZ80589.1 - 0.0082 16.5 0.2 0.017 15.5 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 KNZ80589.1 - 0.042 13.1 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KNZ80589.1 - 0.096 12.1 0.1 0.28 10.6 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 KNZ80589.1 - 0.13 11.7 0.0 0.36 10.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein RasGEF PF00617.19 KNZ80590.1 - 9.1e-43 146.5 0.1 1.8e-42 145.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KNZ80590.1 - 1.2e-14 54.4 0.4 3.1e-14 53.1 0.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KNZ80590.1 - 8.1e-11 41.4 0.8 1.7e-10 40.3 0.8 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KNZ80590.1 - 3.8e-07 29.7 0.0 1.8e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KNZ80590.1 - 1.5e-06 28.0 0.1 3.2e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_L30 PF00327.20 KNZ80591.1 - 1.1e-11 44.4 0.2 1.6e-11 43.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e GWT1 PF06423.12 KNZ80592.1 - 7.6e-33 113.7 0.6 7.6e-33 113.7 0.6 2.8 3 1 0 3 3 3 1 GWT1 F-box-like PF12937.7 KNZ80593.1 - 5e-06 26.3 1.3 2.4e-05 24.1 1.3 2.3 1 0 0 1 1 1 1 F-box-like PSS PF03034.15 KNZ80593.1 - 0.01 15.6 0.4 0.022 14.5 0.4 1.5 1 0 0 1 1 1 0 Phosphatidyl serine synthase F-box PF00646.33 KNZ80593.1 - 0.028 14.3 1.4 0.12 12.2 0.3 2.8 2 0 0 2 2 2 0 F-box domain Ist1 PF03398.14 KNZ80594.1 - 6.9e-64 214.7 2.5 8.6e-64 214.4 2.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Insulin_TMD PF17870.1 KNZ80595.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DSHCT PF08148.12 KNZ80596.1 - 1e-49 168.4 0.2 2e-49 167.4 0.2 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KNZ80596.1 - 2.2e-32 111.7 0.0 3.9e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 KNZ80596.1 - 1.7e-19 70.3 0.1 3.7e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 KNZ80596.1 - 5.7e-17 62.5 0.0 1.1e-15 58.3 0.0 2.4 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.15 KNZ80596.1 - 1.2e-06 28.6 0.0 3.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KNZ80596.1 - 3.1e-05 24.3 0.0 0.0001 22.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF3516 PF12029.8 KNZ80596.1 - 0.0021 17.2 0.3 0.0045 16.1 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3516) DnaB_2 PF07261.11 KNZ80597.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment NCBP3 PF10309.9 KNZ80598.1 - 1.6e-07 31.0 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 KNZ80598.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain RRM_3 PF08777.11 KNZ80598.1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif GTP_EFTU PF00009.27 KNZ80599.1 - 6.5e-67 224.8 0.2 9.5e-67 224.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KNZ80599.1 - 2.1e-13 50.2 0.0 5.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KNZ80599.1 - 1.7e-12 47.5 0.0 5e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ80599.1 - 0.0001 22.3 0.1 0.00022 21.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 KNZ80599.1 - 0.12 12.2 0.2 0.57 9.9 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Acetyltransf_3 PF13302.7 KNZ80600.1 - 9.3e-17 62.0 0.0 1.5e-16 61.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KNZ80600.1 - 5.7e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 KNZ80600.1 - 0.00063 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KNZ80600.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SH3_1 PF00018.28 KNZ80601.1 - 5e-12 45.2 0.1 8.8e-12 44.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ80601.1 - 1.3e-08 34.5 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ80601.1 - 8.6e-07 28.5 0.0 1.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.25 KNZ80602.1 - 1.4e-09 37.6 9.4 2.5e-09 36.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ80602.1 - 6.1e-09 35.6 6.5 9.5e-09 35.0 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ80602.1 - 7.7e-09 35.3 9.2 1.3e-08 34.5 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ80602.1 - 3.9e-08 33.5 9.3 7.3e-08 32.6 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KNZ80602.1 - 9.1e-07 28.8 9.1 5.9e-06 26.2 4.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 KNZ80602.1 - 1.4e-05 24.9 9.3 1.8e-05 24.6 8.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KNZ80602.1 - 3.5e-05 23.9 10.8 7.5e-05 22.8 10.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KNZ80602.1 - 0.00011 22.0 7.7 0.00024 20.9 7.6 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KNZ80602.1 - 0.00039 20.7 7.9 0.00099 19.4 7.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 KNZ80602.1 - 0.013 15.3 8.7 0.025 14.4 8.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 KNZ80602.1 - 0.064 13.3 3.2 0.13 12.4 3.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KNZ80602.1 - 0.26 11.0 10.9 4.6 7.1 7.5 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 KNZ80602.1 - 1.6 8.9 4.9 3.4 7.9 4.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 KNZ80602.1 - 2.4 8.1 5.9 4.1 7.3 4.7 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Wbp11 PF09429.10 KNZ80603.1 - 2.2e-20 72.8 18.3 6e-20 71.4 18.3 1.8 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 KNZ80603.1 - 2e-15 57.2 4.4 2e-15 57.2 4.4 6.3 3 1 0 3 3 3 1 mRNA biogenesis factor APG6_N PF17675.1 KNZ80603.1 - 5.4 7.6 20.9 3.1 8.3 13.5 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region FAD_binding_3 PF01494.19 KNZ80605.1 - 3.3e-14 52.9 0.0 5.8e-11 42.2 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 KNZ80605.1 - 0.0043 16.1 0.1 0.043 12.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 KNZ80605.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HIT PF01230.23 KNZ80606.1 - 1.5e-25 89.8 0.0 2e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KNZ80606.1 - 1.2e-06 29.0 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KNZ80606.1 - 0.032 14.1 0.0 0.05 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 F-box-like PF12937.7 KNZ80607.1 - 4.5e-05 23.3 0.5 0.00016 21.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like Metallophos PF00149.28 KNZ80608.1 - 1.6e-11 45.1 0.8 2.6e-11 44.4 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RSN1_7TM PF02714.15 KNZ80609.1 - 1e-11 44.7 21.4 1.6e-11 44.1 21.4 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KNZ80609.1 - 0.00022 21.0 0.1 0.00022 21.0 0.1 2.7 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 KNZ80609.1 - 0.00053 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Sec1 PF00995.23 KNZ80610.1 - 2.4e-121 406.8 0.0 2.8e-121 406.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Bax1-I PF01027.20 KNZ80611.1 - 4e-37 128.1 8.7 4e-37 128.1 8.7 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 KNZ80612.1 - 4.6e-33 112.7 17.9 1.2e-06 29.1 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ80612.1 - 5.5e-13 49.0 0.3 0.013 15.7 0.0 5.8 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 KNZ80612.1 - 4.3e-05 23.3 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 KNZ80612.1 - 0.0011 18.0 0.1 0.84 8.5 0.0 3.7 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SH3_6 PF12913.7 KNZ80612.1 - 0.015 14.8 0.1 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 SH3 domain (SH3b1 type) Nbas_N PF15492.6 KNZ80612.1 - 0.029 13.7 0.1 1.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 KNZ80612.1 - 0.048 13.0 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KNZ80613.1 - 4.6e-15 55.7 12.7 0.0052 17.6 1.5 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat RicinB_lectin_2 PF14200.6 KNZ80614.1 - 0.00012 22.7 0.0 0.0012 19.5 0.0 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like YonK PF09642.10 KNZ80614.1 - 0.057 13.6 1.4 0.12 12.6 0.3 1.9 2 0 0 2 2 2 0 YonK protein Arginase PF00491.21 KNZ80615.1 - 6.2e-79 265.4 0.0 1e-78 264.7 0.0 1.3 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KNZ80615.1 - 0.038 14.2 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain Abhydrolase_1 PF00561.20 KNZ80616.1 - 9.2e-15 55.0 0.1 5.2e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ80616.1 - 8.7e-05 21.9 0.0 0.00021 20.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 GCFC PF07842.12 KNZ80616.1 - 0.052 13.2 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein SUR7 PF06687.12 KNZ80617.1 - 2.5e-19 69.8 17.6 3.6e-19 69.2 17.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5090 PF17009.5 KNZ80617.1 - 6.1 6.8 6.8 0.65 9.9 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Sin3a_C PF16879.5 KNZ80618.1 - 6.1e-81 272.3 1.0 4.9e-80 269.3 0.0 3.0 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KNZ80618.1 - 4.9e-39 132.3 0.1 1.1e-38 131.3 0.1 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 KNZ80618.1 - 1.8e-35 120.8 13.9 7.9e-15 54.7 0.0 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Zn-C2H2_12 PF18112.1 KNZ80618.1 - 0.0059 17.0 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain SCF PF02404.15 KNZ80619.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor Arm PF00514.23 KNZ80620.1 - 0.0045 17.0 6.6 0.0054 16.7 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat NAD_binding_2 PF03446.15 KNZ80621.1 - 2e-23 83.3 0.0 5.2e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 KNZ80621.1 - 1.6e-09 38.0 0.0 9.3e-09 35.5 0.0 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 KNZ80621.1 - 2.5e-08 34.2 0.2 5.6e-08 33.1 0.0 1.7 2 0 0 2 2 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KNZ80621.1 - 3.8e-06 27.4 0.0 1.2e-05 25.8 0.0 1.9 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.16 KNZ80621.1 - 0.00019 22.1 0.1 0.00042 20.9 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 KNZ80621.1 - 0.00025 20.1 0.0 0.0038 16.2 0.0 2.1 1 1 1 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.24 KNZ80621.1 - 0.00032 21.1 0.0 0.64 10.5 0.0 2.5 1 1 1 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KNZ80621.1 - 0.00085 19.6 0.0 0.003 17.8 0.0 2.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FR47 PF08445.10 KNZ80621.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein ApbA PF02558.16 KNZ80621.1 - 0.023 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KNZ80621.1 - 0.04 13.3 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KNZ80621.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding GFO_IDH_MocA PF01408.22 KNZ80621.1 - 0.087 13.7 0.0 0.19 12.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 KNZ80621.1 - 0.11 12.4 1.3 1.4 8.8 1.3 2.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4164 PF13747.6 KNZ80621.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) GntP_permease PF02447.16 KNZ80621.1 - 0.14 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 GntP family permease DapB_N PF01113.20 KNZ80621.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_Gly3P_dh_N PF01210.23 KNZ80621.1 - 0.17 11.8 0.8 1 9.3 0.2 2.3 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pkinase PF00069.25 KNZ80622.1 - 1e-39 136.5 0.0 1.5e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80622.1 - 5.6e-27 94.7 0.0 7.8e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ80622.1 - 0.0035 16.3 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KNZ80623.1 - 4.6e-11 43.1 0.0 9.6e-11 42.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ80623.1 - 4.1e-06 26.5 0.0 6.3e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ80623.1 - 0.011 15.1 0.0 3.9 6.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 KNZ80623.1 - 0.014 15.0 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Dioxygenase_C PF00775.21 KNZ80624.1 - 0.0054 16.2 0.0 0.0099 15.3 0.0 1.5 1 1 0 1 1 1 1 Dioxygenase Isochorismatase PF00857.20 KNZ80626.1 - 1.9e-27 96.6 0.0 2.6e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family HA2 PF04408.23 KNZ80627.1 - 8.9e-22 77.4 1.1 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KNZ80627.1 - 4.5e-14 52.6 0.0 1.5e-13 50.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KNZ80627.1 - 7.6e-07 29.1 1.1 0.0063 16.3 0.1 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 KNZ80627.1 - 0.0033 17.7 0.5 0.015 15.6 0.5 2.0 1 1 0 1 1 1 1 AAA domain Helicase_C PF00271.31 KNZ80627.1 - 0.0043 17.4 0.3 0.011 16.0 0.3 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KNZ80627.1 - 0.0066 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 KNZ80627.1 - 0.017 14.5 0.0 0.043 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.18 KNZ80627.1 - 0.039 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KNZ80627.1 - 0.04 13.6 0.3 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KNZ80627.1 - 0.055 13.8 0.1 0.22 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KNZ80627.1 - 0.058 13.4 0.0 2.8 7.9 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 KNZ80627.1 - 0.072 13.6 0.1 0.23 12.0 0.0 1.9 2 0 0 2 2 1 0 ABC transporter DND1_DSRM PF14709.7 KNZ80627.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 NACHT PF05729.12 KNZ80627.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.16 KNZ80627.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 KNZ80627.1 - 0.17 11.1 0.3 2.5 7.2 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 KNZ80627.1 - 0.19 11.2 0.1 0.47 9.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region HA2 PF04408.23 KNZ80628.1 - 4.7e-25 88.0 0.9 9.6e-25 87.0 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KNZ80628.1 - 1.7e-24 85.9 0.0 3.5e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KNZ80628.1 - 1.1e-13 51.5 0.0 3e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KNZ80628.1 - 5.1e-09 36.3 0.1 1.1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain T2SSE PF00437.20 KNZ80628.1 - 0.00026 20.2 0.0 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 KNZ80628.1 - 0.008 16.4 1.2 0.023 14.9 0.2 2.3 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 KNZ80628.1 - 0.023 14.5 0.9 2 8.1 0.1 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 KNZ80628.1 - 0.049 13.3 0.1 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KNZ80628.1 - 0.13 12.8 0.1 2.4 8.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter NTF2 PF02136.20 KNZ80629.1 - 0.004 17.7 0.0 0.077 13.6 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KNZ80629.1 - 0.0099 15.8 0.0 0.0099 15.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Exo_endo_phos PF03372.23 KNZ80630.1 - 3.4e-20 72.6 0.0 4.1e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_3 PF07859.13 KNZ80631.1 - 1.7e-46 158.7 0.0 2.4e-46 158.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KNZ80631.1 - 4.7e-14 52.0 0.0 1.2e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 KNZ80631.1 - 0.026 13.4 0.0 0.19 10.6 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_M24 PF00557.24 KNZ80632.1 - 1e-41 143.0 0.1 1.3e-41 142.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 KNZ80632.1 - 0.12 12.9 0.2 0.26 11.7 0.2 1.5 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain PGA2 PF07543.12 KNZ80632.1 - 5.9 6.9 8.7 1.6 8.7 1.3 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 RibD_C PF01872.17 KNZ80633.1 - 6.7e-30 104.4 0.0 9e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain N_BRCA1_IG PF16158.5 KNZ80634.1 - 1.4e-30 106.0 0.1 2.9e-30 105.0 0.1 1.6 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KNZ80634.1 - 2.8e-19 68.6 42.9 5.3e-09 35.8 5.0 4.6 4 0 0 4 4 4 3 Zinc finger, ZZ type C1_2 PF03107.16 KNZ80634.1 - 7.8e-07 29.3 40.8 0.014 15.7 7.5 4.6 4 0 0 4 4 4 4 C1 domain TetR_C_23 PF17931.1 KNZ80635.1 - 0.2 11.8 0.9 24 5.1 0.3 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Aminotran_4 PF01063.19 KNZ80636.1 - 4.4e-20 72.5 0.0 6.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV WD40 PF00400.32 KNZ80637.1 - 1.4e-58 193.4 30.2 2.5e-06 28.1 0.1 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.11 KNZ80637.1 - 1e-49 168.1 0.1 1.6e-49 167.5 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KNZ80637.1 - 6.5e-11 42.4 1.0 1.9 8.8 0.0 7.7 6 3 3 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ80637.1 - 1.3e-06 28.0 0.2 0.00021 20.7 0.0 3.4 4 0 0 4 4 4 1 WD40-like domain Nup160 PF11715.8 KNZ80637.1 - 1.3e-05 24.0 0.5 2 7.0 0.0 4.3 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KNZ80637.1 - 6.9e-05 22.0 0.1 3.7 6.4 0.0 4.2 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 KNZ80637.1 - 0.05 12.7 0.0 9.4 5.2 0.0 3.3 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Forkhead PF00250.18 KNZ80638.1 - 1.1e-18 67.2 0.0 2.7e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain Macoilin PF09726.9 KNZ80638.1 - 0.0002 20.1 2.4 0.00032 19.4 2.4 1.2 1 0 0 1 1 1 1 Macoilin family DUF648 PF04890.13 KNZ80638.1 - 0.0068 16.2 0.3 0.01 15.6 0.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF648) AT_hook PF02178.19 KNZ80638.1 - 0.024 14.5 2.7 0.024 14.5 2.7 3.0 3 0 0 3 3 3 0 AT hook motif ATG16 PF08614.11 KNZ80638.1 - 0.39 10.9 13.2 0.62 10.3 13.2 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 KNZ80638.1 - 0.45 11.0 9.7 0.76 10.3 9.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4337 PF14235.6 KNZ80638.1 - 0.56 10.3 2.6 0.98 9.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Fungal_trans PF04082.18 KNZ80639.1 - 2.2e-15 56.4 0.1 9.6e-12 44.5 0.1 2.5 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ80639.1 - 1e-05 25.5 7.5 1.7e-05 24.9 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIPSNAP PF07978.13 KNZ80640.1 - 1e-33 115.6 1.0 6.4e-28 97.0 0.3 2.1 2 0 0 2 2 2 2 NIPSNAP Proteasome PF00227.26 KNZ80641.1 - 4.9e-38 130.5 0.0 5.6e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 KNZ80641.1 - 0.042 13.9 0.0 0.75 9.9 0.1 2.3 2 0 0 2 2 2 0 Phage late-transcription coactivator MoaC PF01967.21 KNZ80642.1 - 3e-48 163.4 0.6 4.7e-48 162.7 0.6 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KNZ80642.1 - 6e-38 129.7 0.0 1e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KNZ80642.1 - 3.4e-28 99.1 0.0 6.6e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KNZ80642.1 - 5.7e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 KNZ80642.1 - 0.011 15.9 0.0 0.035 14.2 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain GPR_Gpa2_C PF11970.8 KNZ80643.1 - 0.073 13.2 0.9 0.27 11.3 0.5 2.2 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Apis_Csd PF11671.8 KNZ80643.1 - 0.15 12.0 1.5 0.36 10.8 1.5 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein CPW_WPC PF09717.10 KNZ80643.1 - 3.6 8.7 6.1 2 9.4 3.3 2.0 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Mito_carr PF00153.27 KNZ80644.1 - 1.2e-68 227.0 1.0 1.3e-23 82.8 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Met_10 PF02475.16 KNZ80644.1 - 8.7e-63 211.7 0.0 2.3e-62 210.3 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein EF-hand_7 PF13499.6 KNZ80644.1 - 3.5e-17 62.6 1.9 4.3e-06 27.1 0.1 4.3 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 KNZ80644.1 - 9.7e-16 56.1 5.6 4.6e-07 28.9 0.3 5.7 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 KNZ80644.1 - 3.4e-15 54.6 4.8 4.3e-06 26.2 0.2 5.8 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 KNZ80644.1 - 1.6e-09 37.5 2.4 0.0032 17.3 0.4 4.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 KNZ80644.1 - 4.1e-07 29.2 8.1 0.00012 21.4 0.1 3.8 4 0 0 4 4 4 2 EF hand TatD_DNase PF01026.21 KNZ80645.1 - 7.2e-17 61.6 0.0 8.9e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.8 KNZ80646.1 - 4.2e-15 55.8 0.5 4.2e-15 55.8 0.5 3.2 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus Goodbye PF17109.5 KNZ80646.1 - 0.05 14.1 0.9 10 6.6 0.4 2.3 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain AbiH PF14253.6 KNZ80646.1 - 0.08 12.8 0.1 0.091 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Sec20 PF03908.13 KNZ80646.1 - 0.11 12.5 0.2 1.2 9.1 0.0 2.4 2 1 1 3 3 3 0 Sec20 TMPIT PF07851.13 KNZ80646.1 - 0.12 11.6 0.4 0.18 11.1 0.4 1.5 1 0 0 1 1 1 0 TMPIT-like protein FAM184 PF15665.5 KNZ80646.1 - 0.26 11.0 5.2 0.6 9.9 4.0 1.8 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B CK2S PF15011.6 KNZ80646.1 - 0.28 11.1 5.0 0.33 10.8 2.1 2.4 1 1 2 3 3 3 0 Casein Kinase 2 substrate kleA_kleC PF17383.2 KNZ80646.1 - 0.84 10.0 3.9 0.52 10.7 0.4 2.3 1 1 0 2 2 2 0 Uncharacterized KorC regulated protein A Sec34 PF04136.15 KNZ80646.1 - 1.2 9.0 5.7 0.61 9.9 1.4 2.4 2 1 0 3 3 3 0 Sec34-like family DUF4404 PF14357.6 KNZ80646.1 - 1.3 9.7 7.3 1.1e+02 3.6 1.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) CorA PF01544.18 KNZ80646.1 - 1.3 8.2 9.0 0.51 9.6 0.5 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein PI3K_P85_iSH2 PF16454.5 KNZ80646.1 - 1.4 8.5 5.7 11 5.6 1.9 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIVA PF05103.13 KNZ80646.1 - 2.2 8.4 7.2 2.1 8.4 3.9 2.3 2 1 0 2 2 2 0 DivIVA protein APG6_N PF17675.1 KNZ80646.1 - 2.4 8.7 12.0 2 9.0 9.1 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region SnoaL_2 PF12680.7 KNZ80647.1 - 0.00029 21.4 0.0 0.00068 20.2 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain DUF2358 PF10184.9 KNZ80647.1 - 0.0041 17.4 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Lgl_C PF08596.10 KNZ80648.1 - 8.3e-38 130.1 0.0 1.1e-36 126.4 0.0 2.4 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal Synaptonemal_3 PF15191.6 KNZ80648.1 - 0.013 15.2 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 ANAPC4_WD40 PF12894.7 KNZ80648.1 - 0.029 14.6 0.0 0.37 11.1 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Synaptobrevin PF00957.21 KNZ80648.1 - 0.036 13.9 0.4 0.067 13.0 0.4 1.3 1 0 0 1 1 1 0 Synaptobrevin WD40 PF00400.32 KNZ80648.1 - 0.098 13.6 0.0 0.73 10.8 0.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat GP41 PF00517.17 KNZ80648.1 - 0.21 11.4 0.4 4.4 7.2 0.1 2.3 2 0 0 2 2 2 0 Retroviral envelope protein FAM184 PF15665.5 KNZ80649.1 - 7e-05 22.7 14.9 7e-05 22.7 14.9 9.8 2 2 7 9 9 9 1 Family with sequence similarity 184, A and B HalX PF08663.10 KNZ80649.1 - 0.006 16.9 5.8 0.006 16.9 5.8 15.9 15 3 3 19 19 19 2 HalX domain Snapin_Pallidin PF14712.6 KNZ80649.1 - 0.01 16.2 7.3 0.01 16.2 7.3 13.3 7 5 9 16 16 16 0 Snapin/Pallidin MamL-1 PF09596.10 KNZ80649.1 - 7.2 6.9 11.6 1.4 9.2 0.9 4.6 3 0 0 3 3 3 0 MamL-1 domain DUF89 PF01937.19 KNZ80650.1 - 2.5e-104 349.0 0.0 3e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Asp PF00026.23 KNZ80651.1 - 6.9e-43 147.3 5.6 2.3e-42 145.5 5.6 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ80651.1 - 1e-08 35.7 2.6 0.0002 21.7 0.2 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ80651.1 - 0.0017 19.0 3.9 0.016 15.8 0.9 2.8 2 0 0 2 2 2 1 Aspartyl protease ABC_tran PF00005.27 KNZ80652.1 - 6e-49 166.1 0.2 7.9e-28 97.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KNZ80652.1 - 7.3e-49 166.9 22.5 2e-29 103.1 9.5 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KNZ80652.1 - 2.4e-10 40.2 3.2 4.2e-05 23.1 0.2 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KNZ80652.1 - 8.4e-07 28.8 0.2 0.0077 15.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KNZ80652.1 - 9e-07 28.6 1.5 0.0023 17.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KNZ80652.1 - 9.6e-06 26.1 0.1 0.12 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 KNZ80652.1 - 1.6e-05 24.1 0.5 0.028 13.5 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 KNZ80652.1 - 3.2e-05 24.5 2.0 0.0012 19.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KNZ80652.1 - 8.2e-05 22.0 0.1 0.09 12.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 KNZ80652.1 - 0.001 19.4 2.6 0.49 10.7 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 KNZ80652.1 - 0.0012 18.4 0.4 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KNZ80652.1 - 0.0031 17.7 5.7 0.012 15.7 0.3 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KNZ80652.1 - 0.018 14.8 0.1 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KNZ80652.1 - 0.02 14.5 1.5 0.49 10.0 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KNZ80652.1 - 0.022 14.7 1.1 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 KNZ80652.1 - 0.022 14.8 1.1 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 KNZ80652.1 - 0.023 14.8 0.6 7.1 6.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KNZ80652.1 - 0.036 14.4 0.2 10 6.5 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.6 KNZ80652.1 - 0.041 13.9 0.1 31 4.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 KNZ80652.1 - 0.051 14.0 0.2 20 5.6 0.1 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 KNZ80652.1 - 0.061 12.7 1.0 7.3 5.9 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_5 PF07728.14 KNZ80652.1 - 0.069 13.1 0.4 8.9 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RecA PF00154.21 KNZ80652.1 - 0.07 12.6 0.1 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein DUF2075 PF09848.9 KNZ80652.1 - 0.074 12.3 1.7 1.9 7.7 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KNZ80652.1 - 0.083 12.8 0.8 15 5.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 KNZ80652.1 - 0.088 12.5 0.2 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KNZ80652.1 - 0.11 12.2 2.7 12 5.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 KNZ80652.1 - 0.12 11.3 1.8 4 6.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DEAD PF00270.29 KNZ80652.1 - 0.16 11.7 3.0 17 5.1 0.0 3.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase CbiA PF01656.23 KNZ80652.1 - 0.17 12.0 0.0 35 4.5 0.1 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Adeno_IVa2 PF02456.15 KNZ80652.1 - 0.19 10.5 0.9 2.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_18 PF13238.6 KNZ80652.1 - 0.22 12.1 0.3 6.5 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KNZ80652.1 - 0.27 10.5 2.1 2.8 7.2 0.1 2.7 3 0 0 3 3 3 0 KaiC Pox_A32 PF04665.12 KNZ80652.1 - 0.41 10.1 2.6 3.2 7.1 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein SSP160 PF06933.11 KNZ80653.1 - 0.038 12.2 7.0 0.051 11.8 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1515 PF07439.11 KNZ80653.1 - 0.059 13.4 0.1 0.095 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HOK_GEF PF01848.16 KNZ80653.1 - 0.48 9.9 2.7 0.79 9.2 2.7 1.3 1 0 0 1 1 1 0 Hok/gef family Pex14_N PF04695.13 KNZ80653.1 - 5 7.8 10.6 0.067 13.9 3.3 1.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asp PF00026.23 KNZ80654.1 - 3.1e-46 158.2 13.2 7.8e-46 156.9 13.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ80654.1 - 4.2e-09 36.9 3.4 7.4e-05 23.1 0.1 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ80654.1 - 0.0032 18.1 5.5 0.016 15.8 1.0 2.9 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ80654.1 - 0.048 14.2 2.2 0.21 12.2 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KNZ80654.1 - 0.066 13.0 2.5 0.12 12.1 0.2 2.4 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal RNase_H PF00075.24 KNZ80655.1 - 3.7e-19 69.3 0.0 9.8e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 KNZ80655.1 - 0.016 15.9 2.2 0.028 15.1 0.4 2.4 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Glyco_hydro_64 PF16483.5 KNZ80655.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Beta-1,3-glucanase Asp PF00026.23 KNZ80657.1 - 4e-43 148.0 10.2 2.3e-42 145.6 10.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ80657.1 - 1.1e-09 38.8 2.9 9.1e-06 26.0 0.3 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KNZ80657.1 - 0.055 13.2 1.1 0.35 10.7 0.1 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KNZ80657.1 - 0.13 12.9 5.1 0.28 11.9 0.5 3.0 3 1 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 KNZ80657.1 - 0.26 11.8 1.5 1.6 9.3 0.1 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Myosin_head PF00063.21 KNZ80659.1 - 7.1e-234 778.0 1.7 6.6e-233 774.8 1.7 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KNZ80659.1 - 4.1e-45 153.7 0.1 8.9e-45 152.7 0.1 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Hpr_kinase_C PF07475.12 KNZ80659.1 - 0.014 15.0 0.7 6.3 6.3 0.1 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KNZ80659.1 - 0.031 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ80659.1 - 0.033 14.6 0.0 0.12 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KNZ80659.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KNZ80659.1 - 0.13 12.7 0.0 0.86 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Ank_5 PF13857.6 KNZ80660.1 - 2e-10 40.7 0.2 4.6e-10 39.6 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ80660.1 - 1.5e-07 31.9 0.1 2e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ80660.1 - 6.8e-06 26.5 0.0 0.00081 19.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ80660.1 - 0.00013 22.1 0.0 1.8 9.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KNZ80660.1 - 0.00015 22.1 0.2 0.13 12.7 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat PPR_1 PF12854.7 KNZ80660.1 - 0.02 14.6 0.2 0.043 13.5 0.2 1.5 1 0 0 1 1 1 0 PPR repeat PPR PF01535.20 KNZ80660.1 - 0.054 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 PPR repeat UNC45-central PF11701.8 KNZ80661.1 - 5e-17 62.3 0.1 1.6e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Phage_CRI PF05144.14 KNZ80661.1 - 0.074 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage replication protein CRI Gcd10p PF04189.13 KNZ80662.1 - 1.9e-64 217.7 0.0 2.7e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family DUF1726 PF08351.11 KNZ80662.1 - 0.16 11.9 0.1 0.55 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) PXA PF02194.15 KNZ80663.1 - 1e-46 159.2 0.7 4.8e-46 157.0 0.1 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KNZ80663.1 - 3e-28 98.6 1.5 7e-28 97.4 0.1 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 KNZ80663.1 - 1.9e-19 69.7 0.0 1.4e-18 66.9 0.0 2.4 2 0 0 2 2 2 1 PX domain RGS PF00615.19 KNZ80663.1 - 7.1e-10 39.2 0.3 1.9e-09 37.8 0.3 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Mito_carr PF00153.27 KNZ80664.1 - 9.1e-49 163.3 1.2 8.1e-18 64.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cellulase PF00150.18 KNZ80665.1 - 1.1e-15 57.8 0.5 2.3e-15 56.8 0.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAC2 PF09754.9 KNZ80665.1 - 0.21 11.6 0.0 0.3 11.0 0.0 1.2 1 0 0 1 1 1 0 PAC2 family UDPGP PF01704.18 KNZ80666.1 - 1.8e-44 152.0 0.0 2.3e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KNZ80666.1 - 0.05 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.9 KNZ80667.1 - 1.1e-18 67.5 38.3 3.7e-10 39.5 19.1 2.4 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.8 KNZ80667.1 - 1.9e-07 30.8 0.7 0.014 15.2 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like PriA_C PF18074.1 KNZ80667.1 - 0.0048 17.7 0.3 0.0048 17.7 0.3 3.3 3 1 2 5 5 5 1 Primosomal protein N C-terminal domain DUF2935 PF11155.8 KNZ80667.1 - 0.074 13.4 9.8 0.043 14.1 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) ubiquitin PF00240.23 KNZ80667.1 - 0.074 12.8 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family PhyH PF05721.13 KNZ80667.1 - 2 8.6 9.6 0.35 11.1 0.5 3.0 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) BRCA-2_OB1 PF09103.10 KNZ80668.1 - 3.4e-30 104.5 0.0 6.3e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 KNZ80668.1 - 1.5e-06 28.0 0.1 1e-05 25.3 0.1 2.0 2 0 0 2 2 2 1 BRCA2, helical Val_tRNA-synt_C PF10458.9 KNZ80668.1 - 0.011 16.0 0.2 0.036 14.3 0.0 2.0 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Peptidase_M16_C PF05193.21 KNZ80669.1 - 2.4e-29 102.6 0.0 3.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KNZ80669.1 - 1.1e-20 74.1 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ceramidase PF05875.12 KNZ80670.1 - 4.3e-66 223.1 6.7 5e-66 222.8 6.7 1.0 1 0 0 1 1 1 1 Ceramidase Arv1 PF04161.13 KNZ80670.1 - 0.013 15.6 1.2 0.021 15.0 1.2 1.4 1 0 0 1 1 1 0 Arv1-like family DUF2104 PF09877.9 KNZ80670.1 - 0.023 14.9 3.5 0.24 11.7 0.0 3.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2104) EF_TS PF00889.19 KNZ80671.1 - 3e-17 62.9 0.0 2.1e-15 56.9 0.0 2.3 1 1 1 2 2 2 2 Elongation factor TS UBA PF00627.31 KNZ80671.1 - 6.3e-05 22.8 0.3 0.00015 21.6 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 KNZ80671.1 - 0.069 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Gar1 PF04410.14 KNZ80672.1 - 1.1e-33 116.2 1.5 2.4e-33 115.1 0.1 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Ribonuclease_T2 PF00445.18 KNZ80673.1 - 1.3e-39 136.3 0.2 1.9e-39 135.8 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family SAS4 PF15460.6 KNZ80674.1 - 4.2e-06 26.8 4.1 1.3e-05 25.2 4.1 1.9 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 KNZ80674.1 - 0.00034 21.2 0.7 0.00034 21.2 0.7 3.5 2 1 0 2 2 2 1 PEHE domain baeRF_family12 PF18856.1 KNZ80675.1 - 0.14 12.7 6.2 0.28 11.7 6.2 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 DHHC PF01529.20 KNZ80676.1 - 7.7e-38 129.6 7.8 7.7e-38 129.6 7.8 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4052 PF13261.6 KNZ80676.1 - 0.25 11.2 2.5 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4052) Bromodomain PF00439.25 KNZ80677.1 - 2.8e-37 126.6 4.4 7.4e-19 67.6 0.6 2.7 2 0 0 2 2 2 2 Bromodomain YL1 PF05764.13 KNZ80677.1 - 0.00045 20.4 3.4 0.00045 20.4 3.4 2.9 3 0 0 3 3 3 1 YL1 nuclear protein FlgM PF04316.13 KNZ80677.1 - 0.031 14.6 2.6 2.9 8.3 0.1 3.4 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM zf-CCCH PF00642.24 KNZ80677.1 - 0.16 11.9 0.9 0.29 11.1 0.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KNZ80677.1 - 0.16 12.5 0.9 0.4 11.2 0.9 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ApoLp-III PF07464.11 KNZ80677.1 - 1.4 9.0 13.2 0.031 14.4 2.8 3.1 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Atg14 PF10186.9 KNZ80677.1 - 1.7 7.6 10.2 6.5 5.8 10.2 2.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FA_desaturase PF00487.24 KNZ80678.1 - 1.3e-06 28.4 4.9 2.7e-06 27.4 4.9 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KNZ80678.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CutC PF03932.14 KNZ80679.1 - 8.5e-57 191.9 0.0 1e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 CutC family Glyco_hydro_99 PF16317.5 KNZ80679.1 - 0.0089 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 NMO PF03060.15 KNZ80679.1 - 0.22 10.9 0.2 0.35 10.2 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase FtsX PF02687.21 KNZ80680.1 - 5.5 7.5 9.9 0.99 9.9 0.1 2.8 3 0 0 3 3 3 0 FtsX-like permease family Glyco_transf_22 PF03901.17 KNZ80681.1 - 7.6e-79 265.9 21.3 1.3e-78 265.1 21.3 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family CENP-T_C PF15511.6 KNZ80682.1 - 4.1e-07 30.1 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 KNZ80682.1 - 6e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 KNZ80682.1 - 0.00013 22.2 0.0 0.00017 21.9 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KNZ80682.1 - 0.00092 19.5 0.1 0.0017 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KNZ80682.1 - 0.0018 18.6 0.2 0.0021 18.4 0.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 KNZ80682.1 - 0.057 13.5 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Thioredoxin PF00085.20 KNZ80683.1 - 5.7e-25 87.3 0.0 7.6e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNZ80683.1 - 4.5e-07 30.3 0.1 9.6e-06 26.0 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KNZ80683.1 - 1.9e-05 24.9 0.0 0.015 15.6 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 KNZ80683.1 - 0.00012 21.9 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KNZ80683.1 - 0.00018 21.4 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 KNZ80683.1 - 0.00071 19.0 0.0 0.00083 18.8 0.0 1.2 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 KNZ80683.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 KNZ80683.1 - 0.0048 17.0 0.2 0.013 15.7 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KNZ80683.1 - 0.0076 16.0 0.1 0.027 14.2 0.1 1.7 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.16 KNZ80683.1 - 0.028 14.2 0.0 0.037 13.8 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF953 PF06110.11 KNZ80683.1 - 0.13 11.9 0.1 0.68 9.6 0.1 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) dsrm PF00035.26 KNZ80684.1 - 6.7e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 KNZ80684.1 - 0.00027 21.5 0.0 0.00045 20.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KNZ80684.1 - 0.0021 18.2 0.0 0.003 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Pyrophosphatase PF00719.19 KNZ80686.1 - 3.2e-60 202.6 0.2 4.3e-60 202.2 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase GCP_C_terminal PF04130.13 KNZ80687.1 - 9.9e-30 104.0 0.0 1.7e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KNZ80687.1 - 5.5e-24 85.3 0.2 1.6e-22 80.5 0.2 2.2 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF816 PF05674.12 KNZ80687.1 - 0.15 12.0 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF816) RabGAP-TBC PF00566.18 KNZ80688.1 - 4.7e-27 95.1 0.0 1e-26 94.0 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain O-FucT PF10250.9 KNZ80689.1 - 7.6e-10 39.0 0.0 2.4e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EphA2_TM PF14575.6 KNZ80690.1 - 0.0047 17.8 0.0 0.18 12.7 0.0 2.8 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain ApbA_C PF08546.11 KNZ80691.1 - 3.7e-34 117.6 0.0 8.9e-34 116.4 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KNZ80691.1 - 1.4e-20 73.5 0.1 2.9e-20 72.5 0.1 1.5 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 KNZ80692.1 - 1.1e-26 93.7 0.0 1.5e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_P_pop3 PF08228.11 KNZ80693.1 - 1.1e-14 54.8 0.1 6.8e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 RNase P subunit Pop3 Arrestin_C PF02752.22 KNZ80694.1 - 1.6e-13 51.3 0.0 6e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Acetyltransf_1 PF00583.25 KNZ80694.1 - 9.8e-09 35.5 0.0 2.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KNZ80694.1 - 3.1e-07 30.3 0.0 7.2e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KNZ80694.1 - 2e-06 27.8 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arrestin_N PF00339.29 KNZ80694.1 - 0.0005 20.1 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Acetyltransf_7 PF13508.7 KNZ80694.1 - 0.002 18.5 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KNZ80694.1 - 0.031 15.0 0.0 0.063 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KNZ80694.1 - 0.049 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Vta1 PF04652.16 KNZ80695.1 - 3.6e-39 134.0 1.6 6.6e-39 133.2 1.6 1.4 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 KNZ80695.1 - 1e-15 57.1 2.6 1.8e-15 56.3 0.2 2.5 3 0 0 3 3 3 1 Vta1 C-terminal domain DUF4061 PF13270.6 KNZ80696.1 - 0.052 13.9 0.4 4.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Flg_hook PF02120.16 KNZ80696.1 - 0.084 12.8 0.5 2.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK VATC PF18716.1 KNZ80697.1 - 0.14 12.1 3.5 1.4 8.9 1.4 3.0 3 0 0 3 3 3 0 Vms1-associating treble clef domain Integrin_b_cyt PF08725.11 KNZ80700.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain Ribonucleas_3_3 PF14622.6 KNZ80701.1 - 4.5e-16 59.2 0.0 5.6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Lipase_GDSL_2 PF13472.6 KNZ80702.1 - 3.3e-11 43.9 2.3 4.2e-11 43.6 2.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KNZ80702.1 - 0.0001 22.3 0.1 0.00016 21.7 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Big_8 PF17961.1 KNZ80702.1 - 0.013 15.7 1.5 0.013 15.7 1.5 2.0 1 1 0 2 2 2 0 Bacterial Ig domain ALGX PF16822.5 KNZ80702.1 - 0.12 12.1 0.0 7.3 6.2 0.1 2.2 2 0 0 2 2 2 0 SGNH hydrolase-like domain, acetyltransferase AlgX Lipase_GDSL_2 PF13472.6 KNZ80703.1 - 4.1e-07 30.6 0.2 5.1e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KNZ80703.1 - 0.0073 16.3 0.9 0.016 15.2 0.9 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase EstA_Ig_like PF18435.1 KNZ80703.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain Big_8 PF17961.1 KNZ80703.1 - 0.1 12.8 0.6 0.18 12.0 0.6 1.3 1 0 0 1 1 1 0 Bacterial Ig domain SAGA-Tad1 PF12767.7 KNZ80704.1 - 2e-21 76.8 0.0 1.5e-19 70.7 0.0 2.7 1 1 1 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 KNZ80704.1 - 0.02 14.7 0.3 0.042 13.6 0.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family zf-CCCH_4 PF18044.1 KNZ80704.1 - 0.063 13.1 4.6 0.036 13.9 2.1 1.9 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 KNZ80704.1 - 0.13 12.3 1.0 0.4 10.6 1.0 1.8 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mus7 PF09462.10 KNZ80705.1 - 1.9e-28 99.7 0.7 8.7e-28 97.5 0.7 2.0 1 1 0 1 1 1 1 Mus7/MMS22 family EMC3_TMCO1 PF01956.16 KNZ80705.1 - 2.9 7.6 4.9 1.8 8.2 2.2 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Zn_Tnp_IS1595 PF12760.7 KNZ80706.1 - 0.04 13.9 1.3 0.1 12.6 1.3 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain YdjO PF14169.6 KNZ80706.1 - 0.11 12.2 0.3 0.88 9.3 0.0 2.1 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-TFIIB PF13453.6 KNZ80706.1 - 0.11 11.8 0.5 0.71 9.2 0.5 2.2 1 1 0 1 1 1 0 Transcription factor zinc-finger Exo_endo_phos_2 PF14529.6 KNZ80707.1 - 0.0056 16.5 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Herpes_UL82_83 PF05784.11 KNZ80709.1 - 0.057 12.3 0.0 0.06 12.2 0.0 1.0 1 0 0 1 1 1 0 Betaherpesvirus UL82/83 protein N terminus PAT1 PF09770.9 KNZ80710.1 - 7.3e-100 335.6 41.5 3e-99 333.5 41.5 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 hDGE_amylase PF14701.6 KNZ80711.1 - 1.4e-138 462.7 0.0 1.2e-137 459.6 0.0 2.0 1 1 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KNZ80711.1 - 8.7e-120 400.2 0.0 1.2e-119 399.7 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KNZ80711.1 - 1.9e-84 283.3 0.0 3.2e-84 282.6 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Mito_carr PF00153.27 KNZ80711.1 - 5.8e-63 208.9 2.8 7.2e-21 73.9 0.0 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein hGDE_N PF14699.6 KNZ80711.1 - 9.3e-20 70.6 0.0 2.3e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Serine_protease PF18405.1 KNZ80711.1 - 0.46 9.6 2.2 2 7.5 0.3 2.3 1 1 0 2 2 2 0 Gammaproteobacterial serine protease RNase_H PF00075.24 KNZ80712.1 - 0.0008 19.6 0.6 0.016 15.4 0.0 2.5 2 0 0 2 2 2 1 RNase H rve PF00665.26 KNZ80712.1 - 0.0015 18.7 0.0 0.014 15.6 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain DUF1643 PF07799.12 KNZ80712.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) Zn_Tnp_IS1595 PF12760.7 KNZ80712.1 - 0.023 14.7 2.7 0.085 12.8 2.7 1.9 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Asp_protease_2 PF13650.6 KNZ80712.1 - 0.068 13.8 0.0 0.29 11.8 0.0 1.9 2 0 0 2 2 2 0 Aspartyl protease ARF7EP_C PF14949.6 KNZ80713.1 - 0.046 14.3 2.0 0.14 12.8 2.0 1.8 1 0 0 1 1 1 0 ARF7 effector protein C-terminus RT_RNaseH_2 PF17919.1 KNZ80713.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase Histone_H2A_C PF16211.5 KNZ80713.1 - 0.13 12.0 1.4 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 C-terminus of histone H2A RVT_1 PF00078.27 KNZ80715.1 - 0.039 13.5 0.0 0.14 11.7 0.0 1.7 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 KNZ80716.1 - 0.0003 20.8 0.0 0.00098 19.1 0.0 1.8 1 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ80716.1 - 0.00059 20.1 0.0 0.0083 16.4 0.0 2.1 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase Peroxin-22 PF12827.7 KNZ80716.1 - 0.11 12.4 0.0 0.4 10.6 0.0 2.0 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family Terpene_synth_C PF03936.16 KNZ80720.1 - 1.7e-06 27.6 0.0 9.5e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain DUF2600 PF10776.9 KNZ80720.1 - 0.039 12.8 0.1 6.4 5.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2600) zf-H2C2_5 PF13909.6 KNZ80721.1 - 3.6e-08 33.0 8.0 0.0009 18.9 2.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 KNZ80721.1 - 4.6e-07 30.0 0.6 4.6e-07 30.0 0.6 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 KNZ80721.1 - 5.9e-06 26.5 11.9 0.027 14.9 3.0 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ80721.1 - 0.0087 16.8 14.5 2 9.5 1.9 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger RVP_2 PF08284.11 KNZ80722.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Terpene_synth_C PF03936.16 KNZ80723.1 - 1.4e-06 27.9 0.0 2.9e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF2600 PF10776.9 KNZ80723.1 - 0.11 11.3 0.1 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Fer2_3 PF13085.6 KNZ80724.1 - 6.5e-33 113.0 0.0 1e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KNZ80724.1 - 4e-10 40.1 7.2 4e-10 40.1 7.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 KNZ80724.1 - 2.6e-07 30.6 3.6 2.6e-07 30.6 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KNZ80724.1 - 7.4e-07 29.5 8.1 7.4e-07 29.5 8.1 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 KNZ80724.1 - 0.00069 20.2 4.3 0.00069 20.2 4.3 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KNZ80724.1 - 0.0036 17.2 0.3 0.0036 17.2 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 KNZ80724.1 - 0.018 15.2 1.8 0.41 10.9 0.1 2.9 3 1 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 KNZ80724.1 - 4.6 7.5 13.9 4.9 7.4 9.9 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain SecY PF00344.20 KNZ80725.1 - 7e-72 242.3 8.8 8.7e-72 241.9 8.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KNZ80725.1 - 3.7e-19 68.3 0.1 2.2e-18 65.8 0.2 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p DUF805 PF05656.14 KNZ80725.1 - 0.87 10.0 5.7 0.45 10.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) ubiquitin PF00240.23 KNZ80726.1 - 5.2e-34 115.8 0.6 6.7e-34 115.5 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 KNZ80726.1 - 1.2e-27 95.5 5.2 1.8e-27 94.9 5.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 KNZ80726.1 - 2.7e-16 59.1 0.6 4.2e-16 58.5 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KNZ80726.1 - 1.9e-05 25.0 0.1 7.1e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KNZ80726.1 - 0.0043 17.0 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 KNZ80726.1 - 0.0044 17.1 0.1 0.0079 16.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 KNZ80726.1 - 0.0079 16.5 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 KNZ80726.1 - 0.014 15.4 1.0 3.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 KNZ80726.1 - 0.03 14.9 0.0 0.045 14.3 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain MFS_1 PF07690.16 KNZ80727.1 - 1.9e-20 73.1 42.0 2.4e-14 53.0 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SLATT_5 PF18160.1 KNZ80727.1 - 0.43 9.9 1.5 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 FA_desaturase PF00487.24 KNZ80728.1 - 1e-12 48.4 3.9 1e-12 48.4 3.9 2.0 2 0 0 2 2 2 1 Fatty acid desaturase 4HBT PF03061.22 KNZ80729.1 - 6.3e-09 36.1 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KNZ80729.1 - 0.001 19.4 0.0 0.0012 19.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily KH_1 PF00013.29 KNZ80730.1 - 0.18 11.6 0.0 0.38 10.6 0.0 1.5 2 0 0 2 2 2 0 KH domain zf-CCHC PF00098.23 KNZ80731.1 - 0.0034 17.4 0.8 0.005 16.9 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ80731.1 - 0.011 15.4 0.3 0.016 14.9 0.3 1.2 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 KNZ80731.1 - 0.043 13.7 1.7 0.065 13.1 1.7 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 KNZ80731.1 - 0.057 13.2 0.9 0.1 12.3 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF212 PF02681.14 KNZ80731.1 - 0.073 13.2 0.1 0.097 12.8 0.1 1.2 1 0 0 1 1 1 0 Divergent PAP2 family RNase_H PF00075.24 KNZ80733.1 - 1.2e-18 67.6 0.0 6.4e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 RNase H zf-RVT PF13966.6 KNZ80733.1 - 7.4e-05 23.4 0.5 7.4e-05 23.4 0.5 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase RVP_2 PF08284.11 KNZ80734.1 - 0.012 15.4 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease Spo7 PF03907.13 KNZ80735.1 - 1.2e-34 119.7 0.0 1.5e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein DnaJ PF00226.31 KNZ80736.1 - 7.6e-19 67.6 0.5 1.4e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain Amidase PF01425.21 KNZ80737.1 - 1.5e-78 264.8 0.0 3.4e-78 263.6 0.0 1.5 1 1 0 1 1 1 1 Amidase Oxidored_molyb PF00174.19 KNZ80738.1 - 1.6e-54 184.1 0.0 2.6e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KNZ80738.1 - 9.7e-48 161.7 0.1 1.6e-47 160.9 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 KNZ80738.1 - 1.4e-25 89.5 0.0 2.7e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KNZ80738.1 - 3.5e-24 85.6 0.0 8.5e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KNZ80738.1 - 3.8e-16 59.0 0.1 7.8e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KNZ80738.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CBM_4_9 PF02018.17 KNZ80738.1 - 0.057 13.7 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain TOBE_3 PF12857.7 KNZ80738.1 - 0.13 12.2 0.4 7.3 6.6 0.0 2.9 3 0 0 3 3 3 0 TOBE-like domain MFS_1 PF07690.16 KNZ80739.1 - 1.8e-29 102.8 14.1 1.8e-29 102.8 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.14 KNZ80740.1 - 2.5e-37 128.7 0.0 4.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KNZ80740.1 - 1.2e-21 76.9 0.2 4.4e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 KNZ80740.1 - 3.2e-18 65.6 0.0 1.2e-17 63.7 0.0 2.0 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 KNZ80740.1 - 1.8e-13 50.6 9.9 1.5e-11 44.4 2.4 2.9 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.17 KNZ80740.1 - 6.3e-13 48.4 0.0 1.9e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.26 KNZ80740.1 - 1.4e-12 47.3 0.1 9.9e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KNZ80740.1 - 2.9e-11 43.8 0.3 8.2e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 KNZ80740.1 - 1.2e-06 28.3 1.0 0.0069 16.3 0.2 3.8 4 0 0 4 4 4 2 Rubredoxin NAD+ reductase C-terminal domain Amidase PF01425.21 KNZ80741.1 - 5.4e-77 259.7 0.0 1.1e-76 258.6 0.0 1.5 1 1 0 1 1 1 1 Amidase TGT PF01702.18 KNZ80743.1 - 2.6e-36 125.5 0.0 3.7e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_2 PF13347.6 KNZ80744.1 - 1e-12 47.4 11.9 1e-12 47.4 11.9 2.9 2 2 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 KNZ80744.1 - 0.00055 18.9 0.4 0.0011 17.9 0.4 1.7 1 1 0 1 1 1 1 MFS_1 like family Pkinase PF00069.25 KNZ80745.1 - 2.1e-73 246.9 0.0 2.8e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80745.1 - 5e-33 114.5 0.0 7.3e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ80745.1 - 7.5e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KNZ80745.1 - 2.6e-05 23.7 0.0 5.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KNZ80745.1 - 0.00019 20.4 0.0 0.00038 19.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KNZ80745.1 - 0.0068 16.4 0.0 0.026 14.5 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family DNA_pol_A_exo1 PF01612.20 KNZ80746.1 - 3.7e-17 62.6 0.0 6.3e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HMGL-like PF00682.19 KNZ80747.1 - 1.8e-35 122.8 0.0 2.3e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Abhydrolase_6 PF12697.7 KNZ80748.1 - 2.8e-15 57.5 0.0 3.7e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family JmjC PF02373.22 KNZ80749.1 - 1.2e-08 35.3 0.1 7.5e-08 32.8 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase C1_2 PF03107.16 KNZ80749.1 - 0.28 11.5 5.4 0.22 11.9 0.8 2.6 2 0 0 2 2 2 0 C1 domain RT_RNaseH PF17917.1 KNZ80751.1 - 1e-06 29.0 0.1 1.3e-05 25.4 0.0 2.7 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ80751.1 - 0.00046 20.2 0.3 0.0061 16.6 0.0 2.5 2 1 1 3 3 3 1 RNase H-like domain found in reverse transcriptase Herpes_Helicase PF02689.14 KNZ80755.1 - 1.3e-07 30.0 0.0 1.5e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ80755.1 - 5.5e-05 22.9 0.1 0.00015 21.6 0.1 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain HMG_box PF00505.19 KNZ80757.1 - 4.1e-10 39.9 0.1 9.4e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KNZ80757.1 - 0.0002 21.9 0.1 0.00076 20.0 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 KNZ80757.1 - 0.084 12.9 0.8 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Fungal_trans PF04082.18 KNZ80758.1 - 3.1e-14 52.7 1.2 5.3e-14 51.9 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KNZ80758.1 - 4.6e-08 33.1 12.5 0.00034 20.9 2.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ80758.1 - 0.00016 21.9 4.5 0.00016 21.9 4.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ80758.1 - 0.0049 17.6 1.6 0.0049 17.6 1.6 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 KNZ80758.1 - 0.013 15.9 3.6 0.045 14.1 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KNZ80758.1 - 0.033 14.5 2.6 1.1 9.6 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KNZ80758.1 - 0.056 13.5 5.0 0.46 10.6 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger WW PF00397.26 KNZ80759.1 - 0.00019 21.5 0.3 0.0006 19.9 0.3 1.9 1 0 0 1 1 1 1 WW domain DUF2207 PF09972.9 KNZ80759.1 - 0.018 13.8 1.1 0.036 12.9 1.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.12 KNZ80759.1 - 1.3 8.9 3.7 2.1 8.3 1.7 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC SOBP PF15279.6 KNZ80760.1 - 0.013 16.2 1.0 0.025 15.2 1.0 1.7 1 0 0 1 1 1 0 Sine oculis-binding protein gag-asp_proteas PF13975.6 KNZ80763.1 - 0.00092 19.7 0.0 0.012 16.1 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80763.1 - 0.023 15.4 0.0 0.1 13.3 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease zf-C2H2 PF00096.26 KNZ80765.1 - 3.4e-08 33.5 10.1 0.00022 21.5 2.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KNZ80765.1 - 9.5e-07 29.0 9.1 0.0066 16.8 0.1 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KNZ80765.1 - 5.4e-05 23.7 8.2 0.034 15.0 2.0 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNZ80765.1 - 0.021 15.1 3.6 0.11 12.8 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KNZ80765.1 - 0.025 14.6 0.7 0.093 12.8 0.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Xol-1_GHMP-like PF09109.10 KNZ80765.1 - 0.025 14.4 0.1 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Switch protein XOL-1, GHMP-like zf-met PF12874.7 KNZ80765.1 - 0.034 14.5 0.6 0.034 14.5 0.6 2.6 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 KNZ80765.1 - 1.3 9.0 6.8 2.3 8.2 0.7 2.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.10 KNZ80765.1 - 6 7.6 8.4 1.4e+02 3.2 8.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AhpC-TSA_2 PF13911.6 KNZ80766.1 - 2.2e-20 72.9 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KNZ80766.1 - 0.00011 22.1 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNZ80766.1 - 0.0002 21.1 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin EI24 PF07264.11 KNZ80767.1 - 5.3e-10 39.8 7.5 6.6e-10 39.5 7.2 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-MYND PF01753.18 KNZ80768.1 - 5.7e-07 29.5 17.2 1.1e-06 28.6 17.2 1.5 1 1 0 1 1 1 1 MYND finger Rrn6 PF10214.9 KNZ80768.1 - 0.29 9.6 6.6 0.37 9.2 6.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3824 PF12868.7 KNZ80768.1 - 1.4 9.6 15.0 1.9 9.1 14.4 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Glyco_hydro_16 PF00722.21 KNZ80769.1 - 7e-05 22.4 0.0 0.00015 21.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4232 PF14016.6 KNZ80769.1 - 0.05 13.7 0.3 0.093 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) Uricase PF01014.18 KNZ80771.1 - 2.6e-68 228.3 0.7 2.8e-35 121.4 0.2 2.1 2 0 0 2 2 2 2 Uricase EamA PF00892.20 KNZ80772.1 - 4.9e-08 33.2 21.4 5.6e-07 29.8 3.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 KNZ80772.1 - 6.2e-08 32.2 0.9 7.5e-08 31.9 0.9 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 KNZ80772.1 - 8.1e-08 31.9 4.4 1e-06 28.3 0.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CRT-like PF08627.10 KNZ80772.1 - 2.7e-05 23.3 3.6 3.3e-05 23.0 0.5 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 KNZ80772.1 - 0.0001 21.6 6.2 0.00013 21.3 6.2 1.2 1 0 0 1 1 1 1 UAA transporter family Pox_A14 PF05767.12 KNZ80772.1 - 0.016 15.4 4.4 3.1 8.0 0.2 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 SLC35F PF06027.12 KNZ80772.1 - 0.12 11.9 12.2 1.2 8.6 12.1 2.2 1 1 0 1 1 1 0 Solute carrier family 35 ETRAMP PF09716.10 KNZ80773.1 - 0.00024 21.1 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) p450 PF00067.22 KNZ80774.1 - 2.4e-38 132.1 0.0 4.5e-38 131.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_S19e PF01090.19 KNZ80774.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e LSM PF01423.22 KNZ80775.1 - 3e-15 55.7 0.5 3.5e-15 55.4 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KNZ80775.1 - 0.0001 22.4 0.1 0.00014 21.9 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain UPF0016 PF01169.19 KNZ80776.1 - 7.9e-43 144.7 19.2 1.1e-22 80.1 6.6 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 KNZ80776.1 - 0.31 10.7 9.6 0.051 13.2 0.6 2.7 2 2 1 3 3 3 0 Integral membrane protein TerC family Abhydrolase_6 PF12697.7 KNZ80777.1 - 1.2e-15 58.7 0.1 1.5e-15 58.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ80777.1 - 0.018 14.7 0.3 0.12 12.0 0.3 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ80777.1 - 0.033 13.4 0.0 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KNZ80777.1 - 0.096 11.6 0.0 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 Chlorophyllase enzyme GST_N_3 PF13417.6 KNZ80778.1 - 4.4e-12 46.2 0.0 9.3e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ80778.1 - 1.4e-08 34.9 0.0 2.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ80778.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KNZ80778.1 - 0.003 17.8 0.1 0.0047 17.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ80778.1 - 0.0097 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PAS_4 PF08448.10 KNZ80778.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 PAS fold TRI5 PF06330.11 KNZ80779.1 - 7.3e-17 61.3 0.5 8.8e-17 61.0 0.5 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF2947 PF11163.8 KNZ80780.1 - 0.013 15.3 0.3 0.02 14.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2947) Aminotran_3 PF00202.21 KNZ80782.1 - 8.7e-110 367.1 0.0 1.1e-109 366.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KNZ80782.1 - 9.2e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TRI5 PF06330.11 KNZ80783.1 - 4.7e-14 52.0 0.5 6.1e-14 51.7 0.5 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) gag-asp_proteas PF13975.6 KNZ80784.1 - 0.0016 19.0 0.0 0.0027 18.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80784.1 - 0.0081 16.8 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Ribosomal_S6e PF01092.19 KNZ80786.1 - 2.9e-56 188.8 0.0 5e-56 188.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.12 KNZ80787.1 - 1.7e-30 104.9 0.1 3.4e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KNZ80787.1 - 1.5e-15 57.2 0.5 2.2e-15 56.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 KH_1 PF00013.29 KNZ80788.1 - 0.035 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 KH domain Pex24p PF06398.11 KNZ80789.1 - 8e-18 64.6 8.6 7.2e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin TMV_coat PF00721.21 KNZ80790.1 - 0.15 11.9 0.5 0.28 11.0 0.5 1.4 1 1 0 1 1 1 0 Virus coat protein (TMV like) DUF4717 PF15838.5 KNZ80794.1 - 0.08 13.0 0.5 0.33 11.0 0.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) DUF3983 PF13137.6 KNZ80795.1 - 0.055 13.3 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) BTB PF00651.31 KNZ80797.1 - 0.038 14.2 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF3983 PF13137.6 KNZ80797.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) zf-C3HC4_3 PF13920.6 KNZ80798.1 - 3.8e-08 33.0 8.5 1.7e-07 31.0 8.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ80798.1 - 9.3e-07 28.7 6.7 2.1e-06 27.6 6.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KNZ80798.1 - 3.2e-06 26.9 7.5 6.5e-06 25.9 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ80798.1 - 6.9e-05 23.1 7.7 6.9e-05 23.1 7.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KNZ80798.1 - 0.00011 22.1 4.2 0.00011 22.1 4.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KNZ80798.1 - 0.00092 19.0 13.3 0.082 12.8 8.8 3.4 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KNZ80798.1 - 0.0088 15.9 6.1 0.0088 15.9 6.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF1644 PF07800.12 KNZ80798.1 - 0.91 9.6 7.2 8.5 6.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-C3HC4_4 PF15227.6 KNZ80798.1 - 1.8 8.8 13.2 29 4.9 13.4 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING BTB PF00651.31 KNZ80800.1 - 3.6e-06 27.2 0.0 7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CTF_NFI PF00859.18 KNZ80801.1 - 0.031 14.2 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region Ku PF02735.16 KNZ80802.1 - 3e-37 128.3 0.0 8e-37 126.9 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KNZ80802.1 - 3e-21 76.2 0.0 4.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 KNZ80802.1 - 1.1e-15 58.1 0.9 2.6e-15 56.9 0.1 2.1 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 KNZ80802.1 - 4.1e-05 23.2 0.0 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 1 SAP domain VWA_2 PF13519.6 KNZ80802.1 - 0.001 19.7 0.0 0.0099 16.5 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain PTPA PF03095.15 KNZ80803.1 - 6.1e-94 314.8 0.0 7.2e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Orn_Arg_deC_N PF02784.16 KNZ80804.1 - 1.3e-75 254.0 0.0 1.7e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KNZ80804.1 - 1e-15 57.8 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Na_sulph_symp PF00939.19 KNZ80806.1 - 8.3e-28 97.6 29.1 1.7e-27 96.6 29.1 1.5 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KNZ80806.1 - 2e-22 79.8 51.7 3.9e-19 69.0 32.4 2.2 1 1 1 2 2 2 2 Citrate transporter SPX PF03105.19 KNZ80806.1 - 8.1e-13 49.0 0.1 1.2e-12 48.5 0.1 1.2 1 0 0 1 1 1 1 SPX domain F-box-like PF12937.7 KNZ80806.1 - 0.0007 19.4 0.4 0.0025 17.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like Glutaredoxin PF00462.24 KNZ80807.1 - 4.7e-19 68.4 0.0 8.7e-17 61.1 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 KNZ80807.1 - 3.8e-14 52.5 0.0 1.2e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 KNZ80807.1 - 2.4e-06 27.8 0.0 0.0016 18.7 0.0 2.8 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KNZ80807.1 - 0.00027 21.3 0.0 0.039 14.4 0.0 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 KNZ80807.1 - 0.00048 20.1 0.1 0.017 15.0 0.0 2.8 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 KNZ80807.1 - 0.059 13.4 0.2 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain Sigma70_r4_2 PF08281.12 KNZ80807.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Isochorismatase PF00857.20 KNZ80808.1 - 2.3e-15 57.2 0.0 3.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family PIG-X PF08320.12 KNZ80809.1 - 1.4e-35 123.1 0.0 1.6e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 FYRN PF05964.14 KNZ80809.1 - 0.091 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus Hus1 PF04005.12 KNZ80810.1 - 3.5e-77 259.4 1.3 4e-77 259.2 1.3 1.0 1 0 0 1 1 1 1 Hus1-like protein OTT_1508_deam PF14441.6 KNZ80811.1 - 2.5e-08 33.8 0.0 5.8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Mrr_N PF14338.6 KNZ80811.1 - 0.038 14.1 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Mrr N-terminal domain AIRC PF00731.20 KNZ80812.1 - 4.4e-63 211.3 1.0 1.2e-62 209.9 1.0 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KNZ80812.1 - 1.6e-57 193.8 0.0 2.3e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KNZ80812.1 - 9.1e-20 70.1 0.0 1.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KNZ80812.1 - 0.0021 17.6 0.0 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Pec_lyase_C PF00544.19 KNZ80813.1 - 2e-33 115.8 8.5 2.7e-33 115.3 8.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KNZ80813.1 - 3.6e-06 26.9 14.7 0.00052 19.9 6.3 2.3 1 1 0 2 2 2 2 Right handed beta helix region Abhydrolase_6 PF12697.7 KNZ80814.1 - 2.5e-11 44.6 0.1 3.2e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ80814.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Costars PF14705.6 KNZ80815.1 - 3.3e-20 72.0 0.1 7.2e-20 70.9 0.1 1.5 1 1 0 1 1 1 1 Costars Phage_TAC_7 PF10109.9 KNZ80816.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, E, or 41 or 14 YabA PF06156.13 KNZ80816.1 - 0.64 10.7 7.8 6.7 7.4 0.3 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Borrelia_P83 PF05262.11 KNZ80816.1 - 9.9 4.5 14.2 15 3.9 14.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Exo_endo_phos PF03372.23 KNZ80817.1 - 2.4e-08 33.8 0.1 4.4e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ImpE PF07024.13 KNZ80817.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 ImpE protein MFS_1 PF07690.16 KNZ80818.1 - 6.8e-17 61.4 14.3 6.8e-17 61.4 14.3 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KNZ80818.1 - 1.3e-08 34.7 6.5 6.4e-08 32.4 6.5 2.1 1 1 0 1 1 1 1 Nodulin-like DUF2627 PF11118.8 KNZ80818.1 - 1.4 9.5 5.7 4.7 7.9 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) HMGL-like PF00682.19 KNZ80819.1 - 4.9e-55 186.9 0.0 6.5e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KNZ80819.1 - 6.5e-09 35.8 0.1 1.3e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain MFS_1 PF07690.16 KNZ80820.1 - 8.2e-40 136.8 33.3 8.2e-40 136.8 33.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ80820.1 - 2.6e-08 33.2 8.9 2.6e-08 33.2 8.9 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KNZ80820.1 - 7.4e-05 21.4 1.1 0.00012 20.6 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Npa1 PF11707.8 KNZ80821.1 - 8.6e-105 350.8 0.0 1.7e-104 349.9 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KNZ80821.1 - 6.8e-52 176.0 0.2 1.8e-51 174.6 0.2 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Cu-oxidase PF00394.22 KNZ80821.1 - 5.1e-39 133.9 1.1 7.4e-39 133.4 0.2 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ80821.1 - 4.3e-29 100.9 0.7 1.8e-25 89.3 0.0 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ80821.1 - 5.8e-29 100.6 2.9 3.2e-28 98.2 0.4 2.9 3 1 0 3 3 3 1 Multicopper oxidase Creb_binding PF09030.10 KNZ80821.1 - 0.065 13.9 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Creb binding Oxidored_FMN PF00724.20 KNZ80822.1 - 2.1e-100 336.4 0.0 2.4e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family p450 PF00067.22 KNZ80823.1 - 6.7e-54 183.4 0.0 1.3e-53 182.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Jnk-SapK_ap_N PF09744.9 KNZ80824.1 - 0.13 12.5 13.7 0.23 11.7 13.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Lebercilin PF15619.6 KNZ80824.1 - 0.15 11.7 15.4 0.23 11.1 15.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 KNZ80824.1 - 1.9 9.0 15.8 11 6.6 15.8 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 KNZ80824.1 - 2 6.9 7.3 2.7 6.5 7.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMCO5 PF14992.6 KNZ80824.1 - 2.8 7.4 9.4 0.21 11.1 1.4 2.0 1 1 1 2 2 2 0 TMCO5 family YabA PF06156.13 KNZ80824.1 - 2.9 8.6 7.5 4.3 8.0 2.6 2.4 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 KNZ80824.1 - 7.4 7.1 15.3 61 4.2 10.6 3.0 1 1 1 2 2 2 0 Cell division protein ZapB HD PF01966.22 KNZ80826.1 - 5.3e-13 49.3 0.1 1.8e-12 47.5 0.0 1.9 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 KNZ80826.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Thiolase_C PF02803.18 KNZ80828.1 - 4.6e-11 42.4 0.0 1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Na_H_Exchanger PF00999.21 KNZ80830.1 - 7.4e-60 202.7 24.1 9.5e-60 202.4 24.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mob1_phocein PF03637.17 KNZ80830.1 - 0.047 13.7 0.1 9 6.3 0.0 2.3 2 0 0 2 2 2 0 Mob1/phocein family DUF2478 PF10649.9 KNZ80832.1 - 0.21 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Orn_Arg_deC_N PF02784.16 KNZ80833.1 - 3e-71 239.7 0.0 3.7e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KNZ80833.1 - 3e-14 53.0 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Glyco_hydro_53 PF07745.13 KNZ80833.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 F-box-like PF12937.7 KNZ80834.1 - 2.6e-06 27.2 0.1 7e-06 25.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like UbiA PF01040.18 KNZ80835.1 - 9.7e-19 67.6 0.7 9.8e-19 67.6 0.7 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4389 PF14333.6 KNZ80835.1 - 0.95 9.4 6.4 0.13 12.2 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Abhydrolase_6 PF12697.7 KNZ80836.1 - 3.8e-07 30.9 1.9 6.4e-07 30.2 1.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ80836.1 - 8e-07 28.6 0.1 0.00012 21.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Lipase_3 PF01764.25 KNZ80836.1 - 8.3e-05 22.5 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 KNZ80836.1 - 0.0089 16.0 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.21 KNZ80836.1 - 0.017 14.6 0.0 0.087 12.3 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KNZ80836.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1749 PF08538.10 KNZ80836.1 - 0.023 13.8 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PGAP1 PF07819.13 KNZ80836.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Diphtheria_R PF01324.19 KNZ80837.1 - 0.1 12.3 0.1 0.51 10.0 0.0 1.9 1 1 1 2 2 2 0 Diphtheria toxin, R domain Hydrolase_4 PF12146.8 KNZ80838.1 - 2.3e-07 30.3 0.0 5.3e-06 25.9 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ80838.1 - 3.5e-07 31.1 0.2 4.3e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 KNZ80838.1 - 3.1e-05 23.8 0.1 5.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.22 KNZ80838.1 - 0.00042 20.3 0.0 0.00061 19.8 0.0 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 KNZ80838.1 - 0.00094 18.9 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KNZ80838.1 - 0.0053 16.5 0.0 0.0078 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF1749 PF08538.10 KNZ80838.1 - 0.024 13.8 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Peptidase_S9 PF00326.21 KNZ80838.1 - 0.11 12.0 0.0 0.39 10.2 0.0 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 KNZ80838.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase p450 PF00067.22 KNZ80839.1 - 5.9e-64 216.5 0.0 7.5e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KNZ80841.1 - 3.9e-49 167.7 0.0 9.7e-47 159.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KNZ80842.1 - 2e-09 36.9 6.2 2.2e-09 36.7 6.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 KNZ80843.1 - 7.7e-32 110.6 0.0 1.2e-17 63.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 PTPLA PF04387.14 KNZ80843.1 - 0.076 12.7 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA Tannase PF07519.11 KNZ80844.1 - 1.1e-96 324.7 0.0 1.7e-95 320.7 0.0 2.0 1 1 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KNZ80844.1 - 0.0018 17.6 0.0 0.016 14.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ80844.1 - 0.004 16.8 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ80844.1 - 0.074 12.5 0.0 0.94 8.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Lipase3_N PF03893.16 KNZ80845.1 - 0.11 12.5 0.4 3.4 7.8 0.2 2.1 2 0 0 2 2 2 0 Lipase 3 N-terminal region Adeno_E3_14_5 PF04834.12 KNZ80845.1 - 0.16 12.6 1.5 0.18 12.4 0.2 1.7 2 0 0 2 2 2 0 Early E3 14.5 kDa protein T2SSF PF00482.23 KNZ80846.1 - 0.038 13.9 0.1 0.092 12.7 0.1 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F MscS_porin PF12795.7 KNZ80846.1 - 0.16 11.5 5.3 13 5.3 5.3 2.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Rad60-SLD PF11976.8 KNZ80847.1 - 4.5e-23 80.9 0.2 6e-23 80.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KNZ80847.1 - 2.1e-12 46.6 0.1 2.8e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family MatE PF01554.18 KNZ80848.1 - 6.8e-21 74.6 2.2 6.8e-21 74.6 2.2 2.7 3 0 0 3 3 3 2 MatE TPR_12 PF13424.6 KNZ80850.1 - 1.6e-16 60.4 3.1 9.8e-05 22.6 0.0 4.8 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ80850.1 - 6.6e-13 48.7 0.1 5.3e-08 32.6 0.2 3.0 1 1 2 3 3 3 2 MalT-like TPR region TPR_2 PF07719.17 KNZ80850.1 - 3e-08 33.2 15.1 0.094 12.9 0.1 6.3 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ80850.1 - 5e-06 26.9 9.0 7.9 7.6 0.0 7.6 4 2 4 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ80850.1 - 5.3e-06 26.2 9.9 0.82 10.0 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ80850.1 - 4.6e-05 24.0 15.2 0.096 13.4 0.2 5.7 4 3 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ80850.1 - 0.00015 21.5 0.3 4.3 7.6 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HemY_N PF07219.13 KNZ80850.1 - 0.0011 19.1 0.4 10 6.4 0.0 4.6 4 0 0 4 4 4 1 HemY protein N-terminus TPR_19 PF14559.6 KNZ80850.1 - 0.0016 18.9 4.1 4.1 8.0 0.0 4.9 3 2 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ80850.1 - 0.0025 17.6 0.6 12 5.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ80850.1 - 0.0055 16.5 6.7 2.5 8.1 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ80850.1 - 0.03 14.9 2.8 57 4.7 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KNZ80850.1 - 0.038 13.7 2.8 0.15 11.8 0.4 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain Cohesin_load PF10345.9 KNZ80850.1 - 0.039 12.4 0.0 1.1 7.6 0.0 2.3 1 1 1 2 2 2 0 Cohesin loading factor CHB_HEX_C_1 PF13290.6 KNZ80851.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Phage_integrase PF00589.22 KNZ80852.1 - 1.9e-05 24.5 0.0 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 Phage integrase family Phage_int_SAM_1 PF02899.17 KNZ80852.1 - 0.015 15.6 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RHD3 PF05879.12 KNZ80853.1 - 6.5e-251 834.6 6.5 8.3e-250 831.0 6.5 1.9 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 KNZ80853.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GBP PF02263.19 KNZ80853.1 - 4.4e-06 26.1 0.9 7.1e-06 25.5 0.2 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KNZ80853.1 - 2.3e-05 24.5 0.0 4.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 KNZ80853.1 - 0.0027 18.0 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 KNZ80853.1 - 0.083 12.2 0.1 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Septin Roc PF08477.13 KNZ80853.1 - 0.11 12.7 0.5 0.27 11.4 0.1 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AMP-binding PF00501.28 KNZ80854.1 - 2.3e-31 108.8 0.0 3.4e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KNZ80854.1 - 0.00016 21.5 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 KNZ80854.1 - 0.026 15.5 0.0 0.051 14.5 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain HlyIII PF03006.20 KNZ80856.1 - 3e-41 141.6 14.3 5.3e-41 140.8 14.3 1.4 1 0 0 1 1 1 1 Haemolysin-III related Pept_tRNA_hydro PF01195.19 KNZ80857.1 - 3.1e-28 98.9 0.1 3.6e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Glyco_hydro_92 PF07971.12 KNZ80858.1 - 6e-123 411.2 0.4 7.1e-123 410.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KNZ80858.1 - 4.5e-50 170.8 0.0 7.3e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Nas2_N PF18265.1 KNZ80859.1 - 0.0046 16.9 0.5 0.0082 16.0 0.0 1.6 2 0 0 2 2 2 1 Nas2 N_terminal domain CCDC84 PF14968.6 KNZ80859.1 - 0.11 12.0 2.9 0.17 11.4 2.9 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 Plasmodium_Vir PF05795.11 KNZ80859.1 - 1.6 8.1 5.6 2.2 7.6 5.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nas2_N PF18265.1 KNZ80861.1 - 0.01 15.7 0.3 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 Nas2 N_terminal domain DUF4391 PF14335.6 KNZ80861.1 - 0.024 14.3 0.7 0.038 13.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) ABC_tran_CTD PF16326.5 KNZ80861.1 - 0.057 13.7 3.9 0.12 12.6 3.9 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Allexi_40kDa PF05549.11 KNZ80861.1 - 0.11 12.0 0.9 0.23 10.9 0.9 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein Pkinase PF00069.25 KNZ80863.1 - 1.6e-21 76.8 0.0 2.4e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80863.1 - 1.7e-14 53.7 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ80863.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyoxal_oxid_N PF07250.11 KNZ80864.1 - 1.7e-32 112.5 0.3 4.4e-28 98.1 0.3 3.8 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ80864.1 - 5.2e-22 78.0 0.2 1.1e-21 76.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 KNZ80864.1 - 0.014 15.4 0.8 2.4 8.3 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain FYRN PF05964.14 KNZ80864.1 - 0.96 9.3 2.8 2.5 8.0 1.9 2.2 3 0 0 3 3 3 0 F/Y-rich N-terminus HNF-1_N PF04814.13 KNZ80865.1 - 0.037 14.6 1.3 0.055 14.1 1.0 1.4 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus gag-asp_proteas PF13975.6 KNZ80866.1 - 0.003 18.1 0.0 0.0039 17.7 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80866.1 - 0.028 15.1 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease PTPRCAP PF15713.5 KNZ80867.1 - 0.74 10.1 8.1 0.98 9.7 8.1 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated gag-asp_proteas PF13975.6 KNZ80871.1 - 0.00027 21.4 0.0 0.00033 21.2 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80871.1 - 0.021 15.5 0.0 0.024 15.3 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease ArlS_N PF18719.1 KNZ80871.1 - 0.068 13.4 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 ArlS sensor domain NepR PF18557.1 KNZ80871.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Anti-sigma factor NepR Ribosomal_L12 PF00542.19 KNZ80872.1 - 0.16 12.3 2.5 0.35 11.2 2.5 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain HicA_toxin PF07927.12 KNZ80873.1 - 0.0002 21.3 0.1 0.0011 19.0 0.0 2.3 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, Utp14 PF04615.13 KNZ80873.1 - 0.088 11.4 19.1 0.13 10.8 19.1 1.2 1 0 0 1 1 1 0 Utp14 protein LZ_Tnp_IS66 PF13007.7 KNZ80873.1 - 0.18 12.6 2.8 0.85 10.4 2.8 2.2 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain DTHCT PF08070.11 KNZ80873.1 - 0.2 12.4 23.3 2 9.2 4.9 3.6 2 0 0 2 2 2 0 DTHCT (NUC029) region TFIIF_alpha PF05793.12 KNZ80873.1 - 1.9 7.0 22.7 0.038 12.6 3.4 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.12 KNZ80873.1 - 2.6 6.2 8.4 4.6 5.4 8.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus VanZ PF04892.12 KNZ80874.1 - 1.7e-05 25.4 6.7 5.1e-05 23.9 6.7 1.8 1 1 0 1 1 1 1 VanZ like family Polysacc_synt_C PF14667.6 KNZ80874.1 - 0.0017 18.4 0.5 1.7 8.7 0.2 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain Phage_holin_3_3 PF16083.5 KNZ80874.1 - 0.067 13.3 1.2 0.067 13.3 1.2 1.7 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III PTS_EIIC_2 PF13303.6 KNZ80874.1 - 0.18 10.8 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DUF1275 PF06912.11 KNZ80874.1 - 0.48 10.3 6.4 1.2 9.1 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DUF641 PF04859.12 KNZ80875.1 - 0.00027 21.3 2.0 0.39 11.1 0.1 2.4 2 0 0 2 2 2 2 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 KNZ80875.1 - 0.016 14.7 1.7 0.39 10.1 0.0 2.8 3 0 0 3 3 3 0 Golgin subfamily A member 5 DUF1640 PF07798.11 KNZ80875.1 - 0.027 14.5 3.6 0.71 9.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Filament PF00038.21 KNZ80875.1 - 0.055 13.1 1.9 0.93 9.0 0.0 2.2 2 0 0 2 2 2 0 Intermediate filament protein MerR-DNA-bind PF09278.11 KNZ80875.1 - 0.071 13.6 2.6 0.11 13.1 0.5 2.4 2 0 0 2 2 2 0 MerR, DNA binding RasGAP_C PF03836.15 KNZ80875.1 - 0.29 11.3 2.3 10 6.3 0.5 2.5 2 0 0 2 2 2 0 RasGAP C-terminus DUF4349 PF14257.6 KNZ80875.1 - 0.81 9.1 6.4 7.7 5.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) THOC7 PF05615.13 KNZ80875.1 - 0.84 9.9 6.7 2.6 8.3 0.2 2.8 3 0 0 3 3 3 0 Tho complex subunit 7 TIG PF01833.24 KNZ80876.1 - 4.5e-10 39.5 0.4 1.8e-09 37.5 0.0 2.4 3 0 0 3 3 3 1 IPT/TIG domain Ank_2 PF12796.7 KNZ80876.1 - 8.8e-10 39.0 0.8 2.4e-07 31.2 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ80876.1 - 4.6e-08 33.4 0.0 1.7e-05 25.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KNZ80876.1 - 1.9e-07 31.2 0.1 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KNZ80876.1 - 3.2e-07 30.5 0.4 8.8e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ80876.1 - 6.1e-06 26.2 0.0 0.018 15.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat TIG_plexin PF17960.1 KNZ80876.1 - 0.0017 18.3 0.1 0.84 9.7 0.0 2.9 2 0 0 2 2 2 2 TIG domain Ran_BP1 PF00638.18 KNZ80877.1 - 2.7e-11 43.8 0.0 4.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 KNZ80877.1 - 6.2e-06 26.8 1.2 6.2e-06 26.8 1.2 5.8 4 2 1 5 5 5 1 NUP50 (Nucleoporin 50 kDa) RabGAP-TBC PF00566.18 KNZ80878.1 - 3e-52 177.4 0.1 4.1e-52 176.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 KNZ80878.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 RraA-like PF03737.15 KNZ80879.1 - 5.9e-34 117.4 0.0 7.8e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Aldolase/RraA IMS PF00817.20 KNZ80880.1 - 5.1e-42 143.4 0.0 1e-41 142.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 KNZ80880.1 - 4.2e-06 26.8 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 KNZ80880.1 - 5.6e-06 27.1 0.1 2.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain RNF220 PF15926.5 KNZ80880.1 - 0.025 14.2 0.3 0.025 14.2 0.3 1.9 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 DUF5131 PF07505.11 KNZ80884.1 - 0.16 11.4 0.0 0.18 11.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF5131) SlyX PF04102.12 KNZ80885.1 - 0.0088 16.6 2.4 0.0088 16.6 2.4 6.0 2 1 3 6 6 6 1 SlyX Filament PF00038.21 KNZ80885.1 - 5.4 6.5 48.6 0.7 9.4 25.2 3.3 1 1 2 3 3 3 0 Intermediate filament protein UL42 PF17638.2 KNZ80886.1 - 0.074 13.0 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 HCMV UL42 TniQ PF06527.11 KNZ80886.1 - 2.9 8.6 8.8 4.5 8.0 8.8 1.3 1 0 0 1 1 1 0 TniQ RT_RNaseH_2 PF17919.1 KNZ80887.1 - 1.8e-15 56.8 0.1 1.9e-15 56.7 0.1 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ80887.1 - 0.00013 22.2 0.0 0.00024 21.4 0.0 1.4 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Chromo_shadow PF01393.19 KNZ80888.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromo shadow domain UbiA PF01040.18 KNZ80889.1 - 2.1e-32 112.4 22.2 7e-32 110.7 22.2 1.8 1 1 0 1 1 1 1 UbiA prenyltransferase family PP-binding PF00550.25 KNZ80890.1 - 9.7e-18 64.3 5.1 6e-11 42.5 0.6 2.4 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KNZ80891.1 - 1.1e-23 84.0 0.0 1.8e-23 83.3 0.0 1.3 1 1 0 1 1 1 1 Polyketide synthase dehydratase Zip PF02535.22 KNZ80892.1 - 3e-28 99.0 10.6 4.2e-28 98.5 10.6 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.20 KNZ80893.1 - 8.9e-82 274.4 0.0 1.1e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component Peptidase_C48 PF02902.19 KNZ80894.1 - 1.1e-25 90.7 0.0 4.5e-22 78.9 0.0 3.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SKN1 PF03935.15 KNZ80895.1 - 1.8e-203 676.5 1.7 2.2e-203 676.2 1.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PIF1 PF05970.14 KNZ80896.1 - 2.3e-09 36.9 0.0 2.3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ80896.1 - 0.0002 21.1 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ80896.1 - 0.095 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain BESS PF02944.20 KNZ80897.1 - 0.039 13.8 0.1 1 9.2 0.0 2.5 2 0 0 2 2 2 0 BESS motif Herpes_Helicase PF02689.14 KNZ80899.1 - 5.1e-05 21.4 0.0 5.3e-05 21.4 0.0 1.0 1 0 0 1 1 1 1 Helicase RRM_1 PF00076.22 KNZ80901.1 - 1.8e-52 175.0 1.8 4e-16 58.6 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KNZ80901.1 - 2.2e-11 43.4 0.0 5.5e-05 22.9 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KNZ80901.1 - 1.1e-05 25.4 0.1 0.8 9.9 0.0 4.2 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KNZ80901.1 - 3.9e-05 23.6 0.0 2.9 8.0 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 KNZ80901.1 - 0.0049 16.8 0.0 0.85 9.6 0.0 3.4 1 1 1 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 KNZ80901.1 - 0.023 14.5 0.2 8.9 6.1 0.0 2.9 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain TPR_14 PF13428.6 KNZ80901.1 - 0.04 14.8 6.1 44 5.3 0.0 5.5 4 2 2 6 6 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KNZ80901.1 - 0.32 11.1 5.0 0.15 12.1 0.7 2.7 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 6 OB_RNB PF08206.11 KNZ80901.1 - 0.89 9.3 2.4 4 7.2 0.1 2.8 3 0 0 3 3 3 0 Ribonuclease B OB domain RNase_H PF00075.24 KNZ80902.1 - 0.0079 16.4 0.5 0.029 14.5 0.1 2.1 2 0 0 2 2 2 1 RNase H DUF664 PF04978.12 KNZ80902.1 - 0.13 12.6 0.0 0.13 12.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF664) TRAF6_Z2 PF18048.1 KNZ80902.1 - 0.28 11.3 0.4 0.28 11.3 0.4 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 MATH PF00917.26 KNZ80903.1 - 6.1e-06 26.4 0.2 1.3e-05 25.3 0.2 1.5 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 KNZ80903.1 - 0.003 17.8 0.1 2.4 8.4 0.1 3.0 3 0 0 3 3 3 2 BTB/POZ domain RhgB_N PF09284.10 KNZ80904.1 - 1.6e-96 322.7 0.5 2.2e-96 322.3 0.5 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KNZ80904.1 - 2.8e-40 137.9 0.8 5.2e-40 137.0 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III GRASP55_65 PF04495.14 KNZ80905.1 - 1.2e-58 197.3 0.0 1e-41 142.4 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KNZ80905.1 - 2.5e-05 24.0 0.1 0.00019 21.2 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 KNZ80905.1 - 2.5e-05 24.5 0.0 0.31 11.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Ank_2 PF12796.7 KNZ80906.1 - 0.022 15.3 0.0 0.1 13.2 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HABP4_PAI-RBP1 PF04774.15 KNZ80906.1 - 0.07 14.0 1.7 0.1 13.5 0.1 1.9 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Thr_synth_N PF14821.6 KNZ80906.1 - 0.092 13.0 0.0 0.6 10.4 0.0 2.5 3 0 0 3 3 3 0 Threonine synthase N terminus Ank_3 PF13606.6 KNZ80906.1 - 0.12 13.0 0.0 0.69 10.7 0.0 2.3 1 0 0 1 1 1 0 Ankyrin repeat PPR_3 PF13812.6 KNZ80906.1 - 0.16 12.1 0.0 0.52 10.4 0.0 1.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Fungal_trans PF04082.18 KNZ80907.1 - 1.6e-19 69.9 0.0 2.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ80907.1 - 3.2e-08 33.6 10.7 6.5e-08 32.6 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.21 KNZ80908.1 - 3.5e-25 88.8 0.0 6.1e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 ThiF family DUF2924 PF11149.8 KNZ80908.1 - 0.027 14.9 0.1 0.055 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) FAD_binding_2 PF00890.24 KNZ80909.1 - 4.1e-45 154.6 2.8 5.2e-39 134.5 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 KNZ80909.1 - 2.7e-07 30.3 0.3 1.4e-05 24.6 0.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KNZ80909.1 - 5.1e-06 26.3 8.1 6.2e-06 26.0 2.7 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ80909.1 - 5.3e-06 25.9 0.0 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ80909.1 - 0.0001 21.2 3.6 0.084 11.6 0.0 3.1 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.22 KNZ80909.1 - 0.00029 20.0 4.1 0.001 18.3 0.4 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KNZ80909.1 - 0.022 15.0 2.1 0.035 14.3 0.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KNZ80909.1 - 0.064 12.5 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain PLDc_2 PF13091.6 KNZ80910.1 - 2.3e-13 50.2 0.0 1.4e-06 28.2 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KNZ80910.1 - 4.6e-13 48.8 0.5 1.9e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.24 KNZ80910.1 - 0.0021 18.0 0.5 0.0088 16.0 0.2 2.3 2 0 0 2 2 2 1 PX domain PROCN PF08083.11 KNZ80912.1 - 2.1e-233 774.3 10.1 3.8e-233 773.5 9.1 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KNZ80912.1 - 6.4e-127 421.9 0.5 1.6e-126 420.6 0.5 1.7 2 0 0 2 2 2 1 PRP8 domain IV core PRO8NT PF08082.11 KNZ80912.1 - 5.8e-85 282.8 2.4 5.8e-85 282.8 2.4 2.4 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U6-snRNA_bdg PF10596.9 KNZ80912.1 - 2.9e-80 267.8 5.6 5.2e-80 267.0 2.1 2.8 3 0 0 3 3 3 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 KNZ80912.1 - 1.4e-68 229.1 0.1 3.1e-68 228.0 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KNZ80912.1 - 4.9e-46 155.0 0.3 1.1e-45 153.9 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KNZ80912.1 - 6.7e-37 126.2 0.0 1.5e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 KNZ80912.1 - 0.00088 19.2 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PH PF00169.29 KNZ80913.1 - 2e-05 25.1 0.0 7.6e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 PH domain APOBEC3 PF18771.1 KNZ80914.1 - 0.17 12.0 0.2 0.26 11.4 0.2 1.2 1 0 0 1 1 1 0 APOBEC3 SIKE PF05769.11 KNZ80916.1 - 5.2e-08 33.0 13.5 9.4e-06 25.7 7.1 2.3 2 0 0 2 2 2 2 SIKE family TACC_C PF05010.14 KNZ80916.1 - 0.0023 17.7 2.4 0.0049 16.7 2.4 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal NYD-SP28_assoc PF14775.6 KNZ80916.1 - 0.011 15.8 8.7 0.074 13.2 1.4 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Cnn_1N PF07989.11 KNZ80916.1 - 0.034 14.3 2.1 0.034 14.3 2.1 3.1 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 FAM184 PF15665.5 KNZ80916.1 - 0.052 13.3 8.3 0.014 15.1 5.2 1.7 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Nsp1_C PF05064.13 KNZ80916.1 - 0.081 12.7 5.0 0.047 13.5 1.0 2.6 2 1 0 2 2 2 0 Nsp1-like C-terminal region Herpes_BLRF2 PF05812.12 KNZ80916.1 - 0.13 12.5 3.1 0.18 11.9 0.0 2.4 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein DUF641 PF04859.12 KNZ80916.1 - 0.22 11.8 7.2 4.1 7.8 3.1 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 KNZ80916.1 - 0.31 11.7 11.5 5.7 7.6 0.1 3.2 2 1 1 3 3 3 0 Initiation control protein YabA OmpH PF03938.14 KNZ80916.1 - 0.89 9.9 14.6 0.042 14.2 8.6 1.9 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 KNZ80916.1 - 1.2 7.0 4.6 1.4 6.7 4.6 1.1 1 0 0 1 1 1 0 Prominin WXG100 PF06013.12 KNZ80916.1 - 2.6 8.3 7.2 5.5 7.3 0.9 3.4 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Asp_protease_2 PF13650.6 KNZ80918.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ80918.1 - 0.0014 19.1 0.0 0.0022 18.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 KNZ80918.1 - 0.0039 16.9 0.1 0.0078 16.0 0.1 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Ribosomal_S19e PF01090.19 KNZ80920.1 - 3.8e-57 191.8 0.0 4.3e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.7 KNZ80921.1 - 1.8e-10 40.5 0.0 3.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Glyco_transf_28 PF03033.20 KNZ80924.1 - 6.5e-27 94.3 0.0 1.5e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 KNZ80924.1 - 4.5e-09 36.2 0.0 8.2e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.18 KNZ80924.1 - 6.4e-07 28.5 0.0 1.5e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase DAHP_synth_1 PF00793.20 KNZ80925.1 - 6.1e-97 323.8 0.0 7.5e-97 323.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.15 KNZ80926.1 - 1.7e-19 69.2 6.6 2.2e-19 68.8 6.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tam41_Mmp37 PF09139.11 KNZ80926.1 - 0.044 13.2 0.1 0.044 13.2 0.1 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial AhpC-TSA PF00578.21 KNZ80927.1 - 3e-14 53.0 0.0 4.4e-12 46.0 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNZ80927.1 - 3e-07 30.3 0.0 5.7e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Redoxin dsrm PF00035.26 KNZ80928.1 - 2.9e-12 47.1 0.1 1.4e-07 32.1 0.1 2.4 2 1 0 2 2 2 2 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KNZ80928.1 - 0.053 13.8 0.4 13 6.2 0.0 3.0 2 1 0 2 2 2 0 double strand RNA binding domain from DEAD END PROTEIN 1 DUF1876 PF08962.11 KNZ80928.1 - 0.074 13.0 0.3 0.2 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) DUF3198 PF11433.8 KNZ80928.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) NMO PF03060.15 KNZ80929.1 - 9.2e-58 196.2 0.3 4.4e-57 193.9 0.3 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KNZ80929.1 - 3.2e-12 46.1 0.1 3.8e-06 26.1 0.3 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KNZ80929.1 - 0.00042 19.4 0.6 0.00065 18.8 0.6 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase TMP-TENI PF02581.17 KNZ80929.1 - 0.0017 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 KNZ80929.1 - 0.021 14.3 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 KNZ80929.1 - 0.04 13.1 0.2 0.084 12.1 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 KNZ80929.1 - 0.059 12.5 0.2 0.12 11.4 0.2 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 KNZ80929.1 - 0.16 11.9 0.7 0.76 9.8 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) Pkinase PF00069.25 KNZ80930.1 - 7e-53 179.7 0.0 1.1e-52 179.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80930.1 - 2e-22 79.7 0.0 3.1e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ80930.1 - 0.01 14.7 0.1 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 KNZ80930.1 - 0.015 14.9 0.3 0.015 14.9 0.3 2.4 3 0 0 3 3 3 0 RIO1 family FTA2 PF13095.6 KNZ80930.1 - 0.068 12.8 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 KNZ80930.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KNZ80930.1 - 0.088 12.7 0.0 1.9 8.3 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ80931.1 - 1.7e-19 70.3 0.0 1.9e-18 66.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ80931.1 - 4.7e-12 45.7 0.0 7.6e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Plk4_PB1 PF18190.1 KNZ80931.1 - 2.5e-06 27.6 0.0 5.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 Kinase-like PF14531.6 KNZ80931.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Plk4_PB2 PF18409.1 KNZ80931.1 - 0.0014 19.3 0.0 0.0054 17.4 0.0 2.0 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 APH PF01636.23 KNZ80931.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Exo_endo_phos PF03372.23 KNZ80932.1 - 1.6e-08 34.3 1.8 3.8e-08 33.1 0.8 2.1 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family ADAM_spacer1 PF05986.14 KNZ80932.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 ADAM-TS Spacer 1 Exo_endo_phos PF03372.23 KNZ80933.1 - 0.0011 18.5 0.2 0.002 17.7 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Transcrip_act PF04949.13 KNZ80934.1 - 0.0038 17.1 0.2 0.013 15.4 0.2 1.7 1 1 1 2 2 2 1 Transcriptional activator DUF2353 PF09789.9 KNZ80934.1 - 0.01 15.2 0.5 0.013 14.9 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CALCOCO1 PF07888.11 KNZ80934.1 - 0.015 14.2 2.7 0.022 13.7 2.7 1.3 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 KNZ80934.1 - 0.021 15.1 1.0 0.067 13.5 0.6 1.9 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC92 PF14916.6 KNZ80934.1 - 0.026 14.3 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function DHR10 PF18595.1 KNZ80934.1 - 0.027 14.5 5.1 0.044 13.8 5.1 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain HAUS6_N PF14661.6 KNZ80934.1 - 0.1 12.2 0.5 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus NPV_P10 PF05531.12 KNZ80934.1 - 0.35 11.4 2.6 1.4 9.4 0.6 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2205 PF10224.9 KNZ80934.1 - 0.42 10.6 4.1 1.1 9.3 0.9 2.4 1 1 1 2 2 2 0 Short coiled-coil protein POP1 PF06978.11 KNZ80935.1 - 3.9e-47 160.9 15.7 6.9e-26 91.5 4.0 2.5 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KNZ80935.1 - 5.3e-32 110.0 0.1 5.3e-32 110.0 0.1 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 KNZ80935.1 - 4.8e-06 26.1 0.0 0.027 13.8 0.0 3.3 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain Nbl1_Borealin_N PF10444.9 KNZ80936.1 - 5.6e-16 57.9 0.3 1.2e-15 56.9 0.3 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.9 KNZ80936.1 - 0.00012 22.0 3.0 0.00012 22.0 3.0 3.7 3 2 1 4 4 4 2 Cell division cycle-associated protein 8 3Beta_HSD PF01073.19 KNZ80937.1 - 1.3e-66 224.5 0.0 1.9e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KNZ80937.1 - 4e-35 121.4 0.0 5.6e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KNZ80937.1 - 3.6e-20 72.6 0.1 7.8e-19 68.2 0.1 2.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KNZ80937.1 - 6.5e-16 58.3 0.0 8.3e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KNZ80937.1 - 6.4e-15 55.5 0.0 9.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KNZ80937.1 - 1.8e-10 40.4 0.1 2.6e-06 26.8 0.0 2.4 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KNZ80937.1 - 5.3e-07 29.1 1.7 7.8e-06 25.2 1.7 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KNZ80937.1 - 4.9e-05 23.0 0.8 0.00022 20.9 0.8 1.9 1 1 0 1 1 1 1 NmrA-like family NBD_C PF17042.5 KNZ80937.1 - 0.00045 20.8 0.0 0.00073 20.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain KR PF08659.10 KNZ80937.1 - 0.0013 18.7 1.0 0.048 13.6 1.0 2.3 1 1 0 1 1 1 1 KR domain D123 PF07065.14 KNZ80938.1 - 3.6e-96 321.9 1.0 4.1e-96 321.7 1.0 1.0 1 0 0 1 1 1 1 D123 CENP-B_dimeris PF09026.10 KNZ80938.1 - 0.034 14.5 4.1 0.065 13.6 4.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FA_desaturase PF00487.24 KNZ80939.1 - 3.2e-23 82.9 21.5 5.7e-23 82.1 21.5 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KNZ80939.1 - 0.039 14.1 0.1 0.089 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Pkinase PF00069.25 KNZ80940.1 - 1.3e-12 47.6 0.0 3.8e-12 46.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KNZ80940.1 - 0.0013 17.5 0.1 0.0034 16.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 KNZ80940.1 - 0.018 14.3 0.0 0.15 11.3 0.0 2.3 3 0 0 3 3 3 0 Protein tyrosine kinase APH PF01636.23 KNZ80940.1 - 0.032 14.2 0.3 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family TPP_enzyme_N PF02776.18 KNZ80941.1 - 1.4e-31 109.4 0.0 3.9e-31 108.0 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNZ80941.1 - 5.7e-14 52.0 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNZ80941.1 - 2.1e-11 43.8 0.0 6.9e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.18 KNZ80942.1 - 5.7e-36 123.7 0.0 8.5e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNZ80942.1 - 3.8e-16 59.1 0.0 7.9e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNZ80942.1 - 4.1e-11 42.9 0.0 7.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M3 PF01432.20 KNZ80943.1 - 3.1e-133 445.4 0.0 4e-133 445.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 KNZ80943.1 - 0.087 12.4 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like TPP_enzyme_N PF02776.18 KNZ80944.1 - 2.6e-26 92.2 0.1 2.8e-24 85.7 0.1 2.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNZ80944.1 - 5.8e-14 52.0 0.0 1.1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KNZ80944.1 - 2.1e-11 43.9 0.0 6.7e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Usp PF00582.26 KNZ80945.1 - 4.2e-23 82.4 0.1 4.2e-23 82.4 0.1 2.1 2 0 0 2 2 2 1 Universal stress protein family Acetyltransf_CG PF14542.6 KNZ80945.1 - 0.012 15.8 0.3 0.027 14.6 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Pet127 PF08634.10 KNZ80946.1 - 2.7e-107 358.3 0.0 3.5e-107 357.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Arf PF00025.21 KNZ80947.1 - 9.5e-38 129.4 0.0 1.2e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KNZ80947.1 - 1.1e-19 70.6 0.0 1.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ80947.1 - 2.4e-15 56.8 0.0 3.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KNZ80947.1 - 2.5e-09 36.8 0.0 3.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KNZ80947.1 - 2.8e-07 30.1 0.0 3.1e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ80947.1 - 5.7e-07 29.6 0.0 8.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 KNZ80947.1 - 3.7e-05 23.1 0.6 0.00046 19.5 0.2 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 KNZ80947.1 - 0.00069 19.7 0.2 0.067 13.2 0.4 2.2 1 1 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.17 KNZ80947.1 - 0.002 18.0 0.2 0.27 11.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KNZ80947.1 - 0.011 15.3 0.0 0.034 13.7 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KNZ80947.1 - 0.015 15.2 0.0 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF751 PF05421.11 KNZ80947.1 - 0.079 13.7 1.5 0.079 13.7 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF751) DSBA PF01323.20 KNZ80947.1 - 0.082 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain ABC_tran PF00005.27 KNZ80947.1 - 0.2 12.2 0.0 0.6 10.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DUF2205 PF10224.9 KNZ80948.1 - 4.7e-11 42.5 0.3 5.3e-11 42.3 0.3 1.1 1 0 0 1 1 1 1 Short coiled-coil protein DivIC PF04977.15 KNZ80948.1 - 0.031 14.0 0.3 0.039 13.7 0.3 1.2 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 KNZ80948.1 - 0.038 14.6 1.1 0.043 14.5 1.1 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Trimer_CC PF08954.11 KNZ80948.1 - 0.045 13.3 0.2 0.077 12.6 0.2 1.4 1 0 0 1 1 1 0 Trimerisation motif RBD-FIP PF09457.10 KNZ80948.1 - 0.093 12.7 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 FIP domain RPN13_C PF16550.5 KNZ80949.1 - 1e-27 96.5 0.2 2.8e-27 95.1 0.0 1.7 1 1 1 2 2 2 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 KNZ80949.1 - 2.2e-25 89.0 0.0 3.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor zf-Nse PF11789.8 KNZ80951.1 - 3.8e-15 55.4 0.1 7e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KNZ80951.1 - 7.9e-06 25.8 0.2 1.3e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KNZ80951.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BAR_3 PF16746.5 KNZ80951.1 - 0.0047 16.7 0.2 0.0079 15.9 0.2 1.3 1 0 0 1 1 1 1 BAR domain of APPL family U-box PF04564.15 KNZ80951.1 - 0.018 15.2 0.1 0.069 13.3 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-C3HC4 PF00097.25 KNZ80951.1 - 0.033 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Herpes_UL46 PF03387.14 KNZ80951.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL46 protein zf-MIZ PF02891.20 KNZ80951.1 - 0.17 11.7 0.2 0.3 10.9 0.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Ribosom_S12_S23 PF00164.25 KNZ80952.1 - 1.3e-30 105.3 0.5 4e-30 103.8 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S12/S23 PH_4 PF15404.6 KNZ80953.1 - 1.1e-16 61.2 0.1 9.4e-15 54.9 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain AOX PF01786.17 KNZ80954.1 - 1e-90 303.0 0.2 1.3e-90 302.7 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Zn_clus PF00172.18 KNZ80955.1 - 2.3e-06 27.6 5.9 3.8e-06 26.9 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KNZ80955.1 - 3.9e-05 22.8 0.5 0.00019 20.6 0.5 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF281 PF03436.13 KNZ80955.1 - 0.066 13.6 3.0 0.13 12.7 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF281) Tom22 PF04281.13 KNZ80956.1 - 1.2e-37 128.7 2.4 1.4e-37 128.5 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.6 KNZ80957.1 - 5.3e-13 49.3 0.0 7.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KNZ80957.1 - 6.5e-12 45.5 0.0 8.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KNZ80957.1 - 6.6e-11 42.1 0.0 3e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ80957.1 - 6.1e-10 38.6 0.0 1.1e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KNZ80957.1 - 1.7e-09 37.2 0.0 8.8e-08 31.6 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 KNZ80957.1 - 8e-07 28.5 0.5 0.034 13.3 0.0 3.1 1 1 2 3 3 3 3 Male sterility protein GDP_Man_Dehyd PF16363.5 KNZ80957.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KNZ80957.1 - 0.0015 17.8 0.1 0.003 16.8 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KNZ80957.1 - 0.0034 16.9 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ80957.1 - 0.057 13.0 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2462 PF09495.10 KNZ80958.1 - 6.6e-20 71.6 11.9 7.2e-20 71.5 11.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Sas10 PF09368.10 KNZ80960.1 - 3.3e-26 91.6 2.7 3.3e-26 91.6 2.7 3.6 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KNZ80960.1 - 1.8e-05 25.3 0.3 0.00013 22.5 0.3 2.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Fcf2 PF08698.11 KNZ80961.1 - 1.4e-28 99.2 0.0 3.2e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing Cwf_Cwc_15 PF04889.12 KNZ80961.1 - 0.017 14.8 1.9 0.017 14.8 1.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Glycos_transf_2 PF00535.26 KNZ80961.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ubie_methyltran PF01209.18 KNZ80962.1 - 3.6e-77 258.8 0.0 4.5e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 KNZ80962.1 - 4.2e-16 59.4 0.0 9.8e-16 58.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ80962.1 - 8.3e-14 52.0 0.0 1.5e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ80962.1 - 2.9e-12 46.6 0.0 5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ80962.1 - 7.9e-10 39.4 0.0 1.2e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ80962.1 - 8.6e-09 35.4 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 KNZ80962.1 - 0.038 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cullin PF00888.22 KNZ80963.1 - 1.3e-162 542.7 18.1 1.8e-162 542.2 18.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KNZ80963.1 - 3.2e-20 71.9 4.3 5.2e-20 71.3 1.9 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain Spore_III_AB PF09548.10 KNZ80963.1 - 0.032 14.3 2.1 0.1 12.7 2.1 1.9 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Rrf2 PF02082.20 KNZ80963.1 - 0.04 14.3 0.2 0.19 12.1 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator GST_N PF02798.20 KNZ80966.1 - 1.2e-11 44.8 0.0 2.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KNZ80966.1 - 3.3e-09 37.0 0.0 8.5e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ80966.1 - 4.5e-08 33.3 0.0 8.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ80966.1 - 0.00015 21.9 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNZ80966.1 - 0.035 14.1 0.2 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ80966.1 - 0.048 13.8 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MRP-L20 PF12824.7 KNZ80967.1 - 3e-22 79.5 7.9 1.5e-21 77.3 7.9 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Malic_M PF03949.15 KNZ80968.1 - 3e-90 302.0 0.0 4e-90 301.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KNZ80968.1 - 4.6e-60 202.5 0.0 6.9e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain SET PF00856.28 KNZ80969.1 - 2.1e-11 44.5 0.0 7.4e-10 39.5 0.0 2.4 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.23 KNZ80969.1 - 2.8e-09 36.7 0.0 5.8e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KNZ80969.1 - 2.2e-06 27.4 0.2 9.2e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 MafB19-like deaminase Glycos_transf_4 PF00953.21 KNZ80970.1 - 1.2e-30 106.6 7.4 1.2e-30 106.6 7.4 2.6 3 0 0 3 3 3 1 Glycosyl transferase family 4 ICL PF00463.21 KNZ80971.1 - 4.2e-265 880.2 1.8 4.7e-265 880.0 1.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KNZ80971.1 - 1.4e-08 34.5 0.3 3.4e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase F-actin_cap_A PF01267.17 KNZ80972.1 - 1.3e-93 313.3 0.0 1.6e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit RGS PF00615.19 KNZ80974.1 - 0.00034 20.9 0.2 0.023 15.0 0.2 2.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Tcp11 PF05794.13 KNZ80976.1 - 2.2e-81 274.2 0.0 3.9e-79 266.8 0.0 2.0 1 1 0 1 1 1 1 T-complex protein 11 SCRL PF06876.12 KNZ80976.1 - 0.054 13.7 2.0 0.11 12.7 2.0 1.4 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein Toxin_35 PF10530.9 KNZ80976.1 - 0.49 10.4 2.7 0.96 9.5 2.7 1.4 1 0 0 1 1 1 0 Toxin with inhibitor cystine knot ICK or Knottin scaffold ATP-synt_ab PF00006.25 KNZ80977.1 - 2.6e-67 226.6 0.0 3.5e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KNZ80977.1 - 7.1e-10 39.3 0.1 1.4e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 KNZ80977.1 - 0.032 13.2 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) TFCD_C PF12612.8 KNZ80978.1 - 2.6e-41 141.5 0.0 3.2e-39 134.7 0.0 3.1 1 1 0 1 1 1 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.7 KNZ80978.1 - 6.6e-05 23.0 0.0 0.0067 16.5 0.0 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KNZ80978.1 - 8.4e-05 22.5 2.8 0.07 13.4 0.0 5.5 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 KNZ80978.1 - 0.018 15.4 0.3 1.9 8.9 0.0 3.9 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 KNZ80978.1 - 4.5 7.9 7.9 43 4.8 0.0 4.8 6 0 0 6 6 6 0 HEAT-like repeat BUD22 PF09073.10 KNZ80979.1 - 1.2e-72 245.7 21.5 1.4e-72 245.4 21.5 1.1 1 0 0 1 1 1 1 BUD22 Mt_ATP_synt PF15704.5 KNZ80979.1 - 0.01 15.8 5.3 0.012 15.5 3.0 2.2 2 2 0 2 2 2 1 Mitochondrial ATP synthase subunit Sugar_tr PF00083.24 KNZ80980.1 - 3.3e-81 273.4 20.8 4.2e-81 273.1 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PP2C PF00481.21 KNZ80980.1 - 1e-79 267.8 0.0 1.4e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C MFS_1 PF07690.16 KNZ80980.1 - 1.7e-26 93.0 26.2 1.7e-26 93.0 26.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNZ80980.1 - 1e-06 27.5 0.9 1e-06 27.5 0.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CS PF04969.16 KNZ80981.1 - 1.8e-10 41.7 0.1 5.4e-10 40.1 0.1 1.8 2 0 0 2 2 2 1 CS domain gag-asp_proteas PF13975.6 KNZ80984.1 - 0.0068 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80984.1 - 0.061 14.0 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 KNZ80987.1 - 5.6e-05 23.6 0.0 9.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ80987.1 - 0.026 15.2 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Trp_halogenase PF04820.14 KNZ80988.1 - 2e-26 92.8 0.4 1.7e-13 50.2 0.0 3.4 2 2 0 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 KNZ80988.1 - 7e-09 35.4 0.0 1.4e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ80988.1 - 4.8e-06 26.0 0.1 1.1e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KNZ80988.1 - 4.8e-06 26.4 0.1 0.0019 17.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KNZ80988.1 - 1.2e-05 25.5 0.1 4.7e-05 23.5 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KNZ80988.1 - 4.4e-05 22.7 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 KNZ80988.1 - 7.6e-05 22.2 0.3 0.00014 21.3 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KNZ80988.1 - 0.00011 21.0 0.0 0.00019 20.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 KNZ80988.1 - 0.00037 19.7 0.4 0.00068 18.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KNZ80988.1 - 0.00045 20.7 0.0 0.0044 17.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ80988.1 - 0.0045 16.3 0.0 0.0076 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ80988.1 - 0.048 12.9 0.0 0.096 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KNZ80988.1 - 0.054 12.5 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 KNZ80988.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KNZ80988.1 - 0.15 12.6 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding LCAT PF02450.15 KNZ80989.1 - 4.3e-61 207.2 0.1 3e-58 197.8 0.1 3.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Retrotran_gag_2 PF14223.6 KNZ80990.1 - 8.9e-07 28.7 0.4 1.3e-05 24.9 0.4 2.1 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-RVT PF13966.6 KNZ80992.1 - 0.0018 19.0 0.1 0.0044 17.7 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KNZ80992.1 - 0.0078 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 RNase H NACHT PF05729.12 KNZ80994.1 - 8.7e-11 42.0 0.0 1.9e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 KNZ80994.1 - 8.9e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KNZ80994.1 - 0.00016 22.0 0.0 0.0098 16.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KNZ80994.1 - 0.00028 21.2 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ80994.1 - 0.00055 20.4 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KNZ80994.1 - 0.0039 17.6 0.0 0.011 16.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 KNZ80994.1 - 0.0063 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 KNZ80994.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_7 PF12775.7 KNZ80994.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KNZ80994.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KNZ80994.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ank_2 PF12796.7 KNZ80995.1 - 5e-19 68.7 0.4 5.6e-09 36.5 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ80995.1 - 1.2e-17 63.7 2.2 4.9e-09 36.3 0.1 3.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ80995.1 - 6e-16 58.6 0.0 4.8e-07 30.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ80995.1 - 1.4e-15 55.8 0.0 0.00017 21.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 KNZ80995.1 - 2.9e-09 36.9 0.4 0.0037 17.6 0.1 4.7 4 1 0 4 4 4 2 Ankyrin repeat Ad_Cy_reg PF16701.5 KNZ80995.1 - 0.0052 16.6 0.0 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate cyclase regulatory domain HHH_7 PF14635.6 KNZ80995.1 - 0.012 15.9 0.0 0.56 10.6 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif EIIA-man PF03610.16 KNZ80995.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 PTS system fructose IIA component Herpes_Helicase PF02689.14 KNZ80996.1 - 1.2e-05 23.5 0.1 1.3e-05 23.4 0.1 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ80996.1 - 0.021 14.6 0.1 0.052 13.4 0.1 1.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ80997.1 - 1.1e-38 133.4 0.2 1.4e-38 133.0 0.2 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ80997.1 - 0.0045 16.7 0.3 0.02 14.6 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ80997.1 - 0.005 17.2 0.0 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ80997.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ80997.1 - 0.14 12.6 0.1 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 RNA helicase F-box-like PF12937.7 KNZ80998.1 - 6.1e-06 26.0 1.2 1.7e-05 24.6 0.7 2.0 2 0 0 2 2 2 1 F-box-like Chromo PF00385.24 KNZ81000.1 - 4.3e-07 29.7 0.3 7.7e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotran_gag_2 PF14223.6 KNZ81001.1 - 1.4e-10 41.0 0.1 2.2e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type TRI5 PF06330.11 KNZ81002.1 - 1e-17 64.1 0.1 1.4e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) PDEase_II PF02112.15 KNZ81002.1 - 0.0018 17.5 0.3 0.003 16.7 0.3 1.4 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Sec61_beta PF03911.16 KNZ81003.1 - 1.2e-09 38.0 4.4 1.9e-05 24.6 2.5 2.2 2 0 0 2 2 2 2 Sec61beta family zf-RING_2 PF13639.6 KNZ81004.1 - 6e-08 32.9 5.1 6e-08 32.9 5.1 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 KNZ81004.1 - 2.2e-06 27.4 5.0 2.2e-06 27.4 5.0 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ81004.1 - 2.8e-06 27.2 0.9 2.8e-06 27.2 0.9 3.4 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.6 KNZ81004.1 - 6.7e-05 22.8 5.2 6.7e-05 22.8 5.2 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KNZ81004.1 - 7.4e-05 22.5 0.8 7.4e-05 22.5 0.8 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KNZ81004.1 - 0.0011 19.1 2.5 0.0062 16.7 2.3 2.4 1 1 1 2 2 2 1 FYVE zinc finger Prok-RING_4 PF14447.6 KNZ81004.1 - 0.0028 17.5 5.0 0.018 14.9 5.0 2.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KNZ81004.1 - 0.0075 16.4 6.1 0.027 14.6 6.1 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KNZ81004.1 - 1.8 8.5 8.0 0.74 9.6 4.6 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RPN2_C PF18004.1 KNZ81004.1 - 9.5 6.1 11.2 0.6 10.0 3.8 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Synaptobrevin PF00957.21 KNZ81005.1 - 5.5e-25 87.0 1.2 6.1e-25 86.8 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin YwcE PF17368.2 KNZ81005.1 - 0.0061 17.2 0.2 0.0082 16.8 0.2 1.2 1 0 0 1 1 1 1 Spore morphogenesis and germination YwcE CDH-cyt PF16010.5 KNZ81006.1 - 8.5e-27 94.0 1.3 2.3e-26 92.6 0.7 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KNZ81006.1 - 1.2e-16 61.0 0.0 6e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ81006.1 - 5.9e-11 43.1 0.1 1.4e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KNZ81006.1 - 1.2e-06 28.0 0.0 8.9e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KNZ81006.1 - 1.7e-05 24.9 0.1 5.3e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KNZ81006.1 - 4.4e-05 23.2 0.0 0.0002 21.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KNZ81006.1 - 0.00012 21.5 0.2 0.0002 20.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KNZ81006.1 - 0.00028 19.7 0.0 0.00041 19.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 KNZ81006.1 - 0.0004 19.7 0.1 0.00074 18.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ81006.1 - 0.0087 15.3 0.0 0.021 14.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KNZ81006.1 - 0.015 14.6 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KNZ81006.1 - 0.019 14.2 0.2 0.042 13.1 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KNZ81006.1 - 0.026 13.6 0.1 0.04 13.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Acyltransferase PF01553.21 KNZ81007.1 - 4.5e-15 55.5 0.0 7.1e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase GerD PF17898.1 KNZ81007.1 - 0.21 11.5 0.2 0.41 10.6 0.2 1.3 1 0 0 1 1 1 0 Spore germination GerD central core domain TPR_1 PF00515.28 KNZ81008.1 - 1e-13 50.5 10.5 0.045 13.6 0.0 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ81008.1 - 5e-12 45.3 0.2 0.16 12.4 0.0 5.5 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ81008.1 - 1.9e-11 43.1 12.2 0.015 15.4 0.0 9.5 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ81008.1 - 3.6e-09 36.1 4.1 4.1 7.9 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ81008.1 - 3.6e-07 30.5 4.4 1.6 9.8 0.0 7.1 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ81008.1 - 4.6e-07 30.2 5.7 0.051 14.1 0.0 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ81008.1 - 2.7e-06 27.0 0.3 0.12 12.1 0.0 4.4 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 KNZ81008.1 - 3.2e-06 27.3 9.5 0.0039 17.5 0.1 6.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ81008.1 - 5.3e-05 23.0 0.7 0.012 15.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ81008.1 - 8.7e-05 23.1 2.4 0.51 11.0 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ81008.1 - 0.00016 21.7 0.1 1.1 9.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat NYD-SP12_N PF15015.6 KNZ81008.1 - 0.0078 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal ANAPC3 PF12895.7 KNZ81008.1 - 0.018 15.3 0.9 0.33 11.2 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 KNZ81008.1 - 0.052 13.0 0.3 4.9 6.7 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 KNZ81008.1 - 0.053 13.4 0.1 1.5 8.8 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2888 PF11135.8 KNZ81008.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Ribosomal_S11 PF00411.19 KNZ81009.1 - 8.3e-47 158.1 1.7 1e-46 157.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KNZ81009.1 - 0.088 13.1 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) zf-RING_2 PF13639.6 KNZ81010.1 - 1.6e-05 25.1 14.6 3.5e-05 24.0 14.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KNZ81010.1 - 0.00076 19.4 13.7 0.0017 18.3 13.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KNZ81010.1 - 0.0032 17.3 14.7 0.0066 16.3 14.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ81010.1 - 0.032 14.3 9.9 0.032 14.3 9.9 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.6 KNZ81010.1 - 0.061 13.2 15.8 0.13 12.2 15.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KNZ81010.1 - 0.11 12.3 10.9 0.27 11.1 10.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KNZ81010.1 - 0.41 10.9 15.5 0.85 9.8 15.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 KNZ81010.1 - 2.1 8.3 14.4 4.7 7.1 14.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 KNZ81010.1 - 5.2 7.0 8.7 12 5.9 8.7 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF5490 PF17593.2 KNZ81012.1 - 0.036 14.1 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5490) ABC_membrane PF00664.23 KNZ81013.1 - 6e-48 163.9 34.8 1.4e-28 100.3 9.5 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KNZ81013.1 - 1.2e-40 139.2 0.0 2e-20 73.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KNZ81013.1 - 2.1e-07 30.6 1.8 0.0043 16.5 0.0 3.0 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KNZ81013.1 - 0.0074 16.7 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 KNZ81013.1 - 0.0084 16.2 0.2 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin family SbcCD_C PF13558.6 KNZ81013.1 - 0.044 14.0 0.0 12 6.2 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 KNZ81013.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2653 PF10850.8 KNZ81013.1 - 0.074 13.3 0.0 0.37 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) Zeta_toxin PF06414.12 KNZ81013.1 - 0.18 11.0 0.3 0.54 9.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RT_RNaseH PF17917.1 KNZ81015.1 - 1.9e-09 37.7 0.0 4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ81015.1 - 5.8e-06 26.3 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Glyoxalase_4 PF13669.6 KNZ81015.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Beach PF02138.18 KNZ81018.1 - 1e-103 346.5 0.0 1.9e-103 345.6 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 KNZ81018.1 - 2.5e-09 37.5 0.8 6.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KNZ81018.1 - 1.3e-07 31.7 0.0 3.1e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 KNZ81018.1 - 2e-06 27.3 3.1 5.3e-05 22.6 0.2 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF4704) WD40 PF00400.32 KNZ81018.1 - 2.5e-05 24.9 2.7 0.12 13.3 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Tup_N PF08581.10 KNZ81018.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Tup N-terminal zf-met PF12874.7 KNZ81019.1 - 0.0074 16.6 0.2 0.012 15.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CTU2 PF10288.9 KNZ81019.1 - 6.2 7.1 13.9 2.3 8.5 6.3 2.7 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 VIT1 PF01988.19 KNZ81019.1 - 8.5 6.2 10.6 5.1 6.9 5.4 2.1 2 0 0 2 2 2 0 VIT family Carb_kinase PF01256.17 KNZ81020.1 - 0.097 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate kinase APH PF01636.23 KNZ81021.1 - 5.2e-10 39.7 0.0 1.2e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family gag_pre-integrs PF13976.6 KNZ81022.1 - 1.1e-07 31.6 1.4 2.3e-07 30.5 0.4 2.2 3 0 0 3 3 3 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 KNZ81023.1 - 0.00025 20.7 0.1 0.00037 20.2 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 KNZ81023.1 - 0.039 13.6 2.4 0.089 12.5 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KNZ81023.1 - 0.17 11.7 0.3 0.51 10.2 0.3 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PAZ PF02170.22 KNZ81024.1 - 0.074 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 PAZ domain ArfGap PF01412.18 KNZ81025.1 - 6.1e-21 74.7 0.0 1.1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Bac_rhamnosid_N PF08531.10 KNZ81027.1 - 0.074 12.9 0.2 3 7.6 0.1 3.0 1 1 0 2 2 2 0 Alpha-L-rhamnosidase N-terminal domain SNF2_N PF00176.23 KNZ81028.1 - 5.3e-68 229.3 0.2 1e-67 228.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ81028.1 - 7.5e-20 71.3 0.0 1.9e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KNZ81028.1 - 4.4e-06 26.8 0.0 1.4e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KNZ81028.1 - 0.00011 21.5 0.3 0.00044 19.5 0.1 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 KNZ81028.1 - 0.0088 15.8 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase EST1_DNA_bind PF10373.9 KNZ81029.1 - 7.3e-27 94.6 0.2 2e-25 89.8 0.0 3.1 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KNZ81029.1 - 5.7e-21 75.6 0.0 3.1e-20 73.2 0.0 2.4 2 0 0 2 2 2 1 Telomerase activating protein Est1 DUF5572 PF17733.1 KNZ81030.1 - 2.4e-18 65.7 1.3 2.9e-18 65.4 0.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5572) MIT PF04212.18 KNZ81030.1 - 0.046 13.8 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain UCH PF00443.29 KNZ81032.1 - 3.5e-07 30.0 0.0 6.9e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.16 KNZ81032.1 - 0.002 17.8 0.1 0.0062 16.2 0.0 2.0 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 KNZ81032.1 - 0.068 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain Epimerase PF01370.21 KNZ81033.1 - 1.8e-19 70.1 0.1 8.7e-19 67.9 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KNZ81033.1 - 2.5e-11 43.1 0.0 5.8e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KNZ81033.1 - 1.9e-09 37.7 0.1 1.9e-09 37.7 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KNZ81033.1 - 6.9e-09 35.6 0.0 9.3e-08 31.8 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KNZ81033.1 - 3.8e-06 26.3 0.0 0.00011 21.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 KNZ81033.1 - 0.021 14.4 0.3 0.096 12.2 0.6 1.8 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 KNZ81033.1 - 0.15 11.2 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Dus PF01207.17 KNZ81034.1 - 6.9e-53 179.8 0.0 1.5e-52 178.6 0.0 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) FA_desaturase PF00487.24 KNZ81034.1 - 1.2e-25 90.8 24.6 1.8e-25 90.2 24.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase zf-CCCH_4 PF18044.1 KNZ81034.1 - 3.7e-07 29.8 10.4 0.00075 19.2 0.3 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger DUF3474 PF11960.8 KNZ81034.1 - 7.7e-05 22.9 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Torus PF16131.5 KNZ81034.1 - 0.01 16.5 1.8 0.16 12.7 0.1 2.5 2 0 0 2 2 2 0 Torus domain zf-CCCH PF00642.24 KNZ81034.1 - 0.02 14.8 9.0 0.12 12.3 3.7 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 KNZ81034.1 - 0.27 11.8 4.9 0.63 10.6 0.3 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger AMP-binding PF00501.28 KNZ81035.1 - 5.5e-83 278.9 0.0 6.7e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ81035.1 - 1.3e-11 45.2 0.2 3.2e-11 44.0 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RMI1_N PF08585.12 KNZ81035.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 RecQ mediated genome instability protein UDPG_MGDP_dh_N PF03721.14 KNZ81036.1 - 5.4e-60 202.2 0.0 8.9e-60 201.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KNZ81036.1 - 1.9e-35 121.5 0.1 2.7e-34 117.8 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 KNZ81036.1 - 9.9e-31 105.8 0.0 2.1e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain F420_oxidored PF03807.17 KNZ81036.1 - 0.079 13.6 0.6 1.7 9.3 0.1 3.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase_Tyr PF07714.17 KNZ81037.1 - 1.6e-42 145.6 0.0 5.6e-42 143.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KNZ81037.1 - 1.3e-38 132.9 0.0 2.2e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KNZ81037.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KNZ81037.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_A_type_inc PF04508.12 KNZ81040.1 - 0.011 15.6 0.5 0.023 14.5 0.5 1.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PTPlike_phytase PF14566.6 KNZ81040.1 - 0.2 11.7 0.9 0.3 11.2 0.8 1.4 1 1 0 1 1 1 0 Inositol hexakisphosphate Prefoldin PF02996.17 KNZ81040.1 - 0.53 10.2 3.5 0.58 10.1 0.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit SET PF00856.28 KNZ81042.1 - 3.2e-19 69.9 9.3 3.8e-19 69.7 0.1 3.6 2 2 0 2 2 2 1 SET domain N-SET PF11764.8 KNZ81042.1 - 2.7e-09 37.4 9.5 2.7e-09 37.4 9.5 3.7 2 2 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KNZ81042.1 - 0.00053 19.6 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated PIG-S PF10510.9 KNZ81042.1 - 4.6 6.0 10.2 8.4 5.1 10.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Glyco_transf_41 PF13844.6 KNZ81042.1 - 7.1 4.9 8.8 13 4.1 8.8 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 41 DUF4778 PF16008.5 KNZ81042.1 - 9 6.2 11.1 1.1 9.2 4.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) RNase_H PF00075.24 KNZ81045.1 - 8.7e-10 38.9 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 RNase H AraC_N PF06719.13 KNZ81046.1 - 0.12 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus Aldedh PF00171.22 KNZ81047.1 - 4.4e-104 348.6 0.0 4.7e-101 338.6 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family DUF4129 PF13559.6 KNZ81047.1 - 1.1 9.6 4.9 0.4 11.0 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) WD40 PF00400.32 KNZ81048.1 - 2.5e-06 28.1 12.5 0.016 16.1 0.1 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 KNZ81048.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 KNZ81048.1 - 0.016 15.5 0.0 2.8 8.3 0.0 3.6 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CDC27 PF09507.10 KNZ81048.1 - 0.1 12.0 14.7 0.15 11.4 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 KNZ81048.1 - 0.22 9.7 12.0 0.31 9.3 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 KNZ81048.1 - 1.2 7.8 6.0 1.7 7.3 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 KNZ81048.1 - 1.9 8.2 6.9 3.7 7.3 6.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 KNZ81048.1 - 3.7 5.6 17.9 4.9 5.2 17.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KNZ81048.1 - 8.4 5.7 19.6 13 5.1 19.6 1.3 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.7 KNZ81049.1 - 5e-10 39.1 4.3 1.3e-09 37.8 4.3 1.8 1 0 0 1 1 1 1 F-box-like Ribonuc_2-5A PF06479.12 KNZ81050.1 - 8.2e-45 152.1 0.1 5.6e-44 149.4 0.1 2.2 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 KNZ81050.1 - 1.1e-37 129.8 0.0 5.1e-35 121.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81050.1 - 2.7e-19 69.5 0.0 2.3e-17 63.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.6 KNZ81050.1 - 5.9e-05 22.8 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 KNZ81050.1 - 0.0002 21.1 0.0 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 PQQ enzyme repeat Pkinase_fungal PF17667.1 KNZ81050.1 - 0.0034 16.2 0.0 0.0085 14.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 KNZ81050.1 - 0.071 13.0 0.2 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ81050.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5353 PF17304.2 KNZ81051.1 - 0.092 12.5 1.0 6.5 6.6 0.0 2.5 1 1 0 2 2 2 0 Family of unknown function (DUF5353) MoCF_biosynth PF00994.24 KNZ81052.1 - 4.1e-33 114.1 0.0 7.3e-33 113.3 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain GPI-anchored PF10342.9 KNZ81053.1 - 1.7e-10 41.5 1.1 1.7e-10 41.5 1.1 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Podoplanin PF05808.11 KNZ81053.1 - 0.011 15.8 0.7 0.011 15.8 0.7 1.8 2 0 0 2 2 2 0 Podoplanin Con-6 PF10346.9 KNZ81054.1 - 2.6e-45 152.1 15.0 1.8e-16 59.8 1.9 3.2 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.7 KNZ81054.1 - 0.00026 20.9 2.0 0.25 11.1 0.0 2.9 3 0 0 3 3 3 2 SpoIIIAH-like protein PLN_propep PF16485.5 KNZ81054.1 - 0.047 13.4 2.1 17 5.2 0.0 3.3 3 0 0 3 3 3 0 Protealysin propeptide YhzD PF14120.6 KNZ81054.1 - 0.067 13.3 4.8 16 5.7 0.1 3.3 3 0 0 3 3 3 0 YhzD-like protein GA-like PF17573.2 KNZ81054.1 - 1.5 8.8 0.0 1.5 8.8 0.0 2.5 3 0 0 3 3 3 0 GA-like domain ATP-synt_DE PF00401.20 KNZ81054.1 - 3 8.2 9.7 17 5.8 0.9 3.3 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pkinase PF00069.25 KNZ81055.1 - 1.6e-28 99.9 0.0 2.4e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81055.1 - 5.7e-14 52.0 0.0 6e-13 48.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ81055.1 - 0.00054 19.4 0.0 0.0034 16.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ81055.1 - 0.1 12.5 0.2 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family WH1 PF00568.23 KNZ81056.1 - 7.4e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 KNZ81056.1 - 0.00028 21.2 0.1 0.00056 20.2 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain UPF0139 PF03669.13 KNZ81057.1 - 0.00076 19.3 0.2 0.00089 19.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) CitMHS PF03600.16 KNZ81058.1 - 1.4e-13 50.7 33.9 7.3e-12 45.1 16.2 2.8 1 1 2 3 3 3 2 Citrate transporter ArsB PF02040.15 KNZ81058.1 - 2.3e-07 30.5 24.2 1.3e-05 24.8 11.2 2.5 2 1 0 2 2 2 2 Arsenical pump membrane protein CorA PF01544.18 KNZ81059.1 - 0.0011 18.3 12.7 0.0095 15.3 12.7 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_127 PF07944.12 KNZ81060.1 - 4.5e-22 78.3 0.0 4.1e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 Gly_transf_sug PF04488.15 KNZ81061.1 - 1.4e-05 25.6 0.0 3.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KNZ81061.1 - 0.044 13.2 0.3 0.068 12.5 0.3 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein tRNA-synt_2b PF00587.25 KNZ81062.1 - 1.1e-35 123.2 0.0 2e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KNZ81062.1 - 1.8e-20 73.2 3.2 1.8e-20 73.2 3.2 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain SYF2 PF08231.12 KNZ81065.1 - 1.4e-61 207.5 7.6 1.4e-61 207.5 7.6 1.7 2 0 0 2 2 2 1 SYF2 splicing factor 5_nucleotid PF05761.14 KNZ81065.1 - 4.5 6.1 8.9 0.099 11.5 0.4 1.9 2 0 0 2 2 2 0 5' nucleotidase family TSC22 PF01166.18 KNZ81066.1 - 0.21 11.9 1.1 0.44 10.9 1.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family LRR_4 PF12799.7 KNZ81069.1 - 0.0056 17.1 9.4 29 5.3 0.0 4.9 4 1 2 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KNZ81069.1 - 0.0083 16.1 8.3 23 5.3 0.2 6.0 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 KNZ81069.1 - 0.017 14.9 8.5 8.1 6.3 2.5 4.6 4 1 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.33 KNZ81069.1 - 0.093 13.3 5.4 69 4.6 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat GPI-anchored PF10342.9 KNZ81070.1 - 6.6e-05 23.6 1.3 0.00015 22.4 0.0 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAD_binding_4 PF07993.12 KNZ81072.1 - 1e-29 103.5 0.0 1.5e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ81072.1 - 9.9e-23 80.4 0.0 2.1e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KNZ81072.1 - 0.00018 21.1 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DctP PF03480.13 KNZ81072.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 2-Hacid_dh_C PF02826.19 KNZ81073.1 - 4e-51 172.9 0.0 5.2e-51 172.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KNZ81073.1 - 6.8e-24 84.0 0.0 5.9e-21 74.5 0.0 2.0 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KNZ81073.1 - 4e-07 30.3 0.0 9.1e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KNZ81073.1 - 0.012 15.7 0.2 0.073 13.1 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_C PF03720.15 KNZ81073.1 - 0.075 13.5 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain IlvN PF07991.12 KNZ81073.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MFS_1 PF07690.16 KNZ81074.1 - 1.8e-27 96.2 19.3 2.5e-27 95.7 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4083 PF13314.6 KNZ81074.1 - 0.24 11.4 2.1 0.28 11.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) PIF1 PF05970.14 KNZ81075.1 - 3.6e-11 42.8 0.1 4.1e-11 42.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase fn3_3 PF14686.6 KNZ81076.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II CCDC24 PF15669.5 KNZ81076.1 - 9.8 6.0 8.2 23 4.8 4.6 2.4 1 1 1 3 3 3 0 Coiled-coil domain-containing protein 24 family WW PF00397.26 KNZ81078.1 - 0.00085 19.4 2.1 0.0013 18.8 0.1 2.2 2 0 0 2 2 2 1 WW domain SCAB_CC PF16712.5 KNZ81078.1 - 0.084 12.7 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein NAD_binding_4 PF07993.12 KNZ81080.1 - 1.5e-28 99.7 0.0 2.2e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KNZ81080.1 - 9.9e-27 93.6 0.0 2.6e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 KNZ81080.1 - 3e-05 23.6 0.0 6.2e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ81080.1 - 0.024 14.5 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 KNZ81080.1 - 0.055 13.9 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PP-binding PF00550.25 KNZ81080.1 - 0.13 12.7 0.1 1.3 9.4 0.0 2.7 3 0 0 3 3 3 0 Phosphopantetheine attachment site zf-RVT PF13966.6 KNZ81082.1 - 0.029 15.1 0.8 0.093 13.4 0.8 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase A2L_zn_ribbon PF08792.10 KNZ81082.1 - 0.22 11.3 0.6 0.78 9.5 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Glyco_transf_8 PF01501.20 KNZ81083.1 - 4.7e-15 55.8 0.7 2.3e-12 47.0 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 KNZ81083.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_24 PF18404.1 KNZ81083.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 Molybdopterin PF00384.22 KNZ81084.1 - 9.7e-59 199.4 0.0 1.3e-29 103.4 0.0 2.3 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KNZ81084.1 - 1.1e-19 70.3 0.3 2.9e-19 68.9 0.3 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KNZ81084.1 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 KNZ81084.1 - 1.9e-14 54.1 0.0 4.3e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 KNZ81084.1 - 1.3e-08 34.6 0.6 1.3e-08 34.6 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 KNZ81084.1 - 0.18 11.7 1.1 4.9 7.1 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Promethin PF16015.5 KNZ81085.1 - 1.9e-12 47.0 18.1 2.6e-12 46.6 18.1 1.2 1 0 0 1 1 1 1 Promethin DUF2207 PF09972.9 KNZ81085.1 - 0.031 13.0 1.8 0.042 12.6 1.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Aa_trans PF01490.18 KNZ81087.1 - 3e-73 246.9 27.7 3.4e-73 246.7 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3278 PF11683.8 KNZ81087.1 - 7.4 6.7 8.3 8.7 6.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) fn3_4 PF16794.5 KNZ81089.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Fibronectin-III type domain MIP PF00230.20 KNZ81091.1 - 2.9e-49 167.8 12.0 3.5e-49 167.6 12.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein PAP2_C PF14360.6 KNZ81091.1 - 0.092 13.3 0.6 4 8.1 0.0 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal PAP2 PF01569.21 KNZ81091.1 - 2.6 7.8 11.0 0.27 11.0 0.5 2.7 2 1 0 2 2 2 0 PAP2 superfamily MIP PF00230.20 KNZ81092.1 - 1.1e-52 179.1 10.3 1.2e-52 178.9 10.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2721 PF11026.8 KNZ81092.1 - 0.11 12.3 1.5 1.1 9.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MIP PF00230.20 KNZ81093.1 - 8.5e-53 179.4 12.1 9.7e-53 179.2 12.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein Phage_integrase PF00589.22 KNZ81095.1 - 0.00021 21.1 0.0 0.00051 19.9 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family Tnp_22_dsRBD PF17490.2 KNZ81096.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain fn3_3 PF14686.6 KNZ81096.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II MitMem_reg PF13012.6 KNZ81097.1 - 0.026 15.0 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Pectate_lyase PF03211.13 KNZ81098.1 - 1e-81 273.4 4.1 1.6e-81 272.7 4.1 1.3 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 KNZ81098.1 - 1.8e-25 89.6 31.3 2.9e-25 88.9 31.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DDE_1 PF03184.19 KNZ81098.1 - 2.6e-21 76.0 2.1 3.7e-18 65.8 0.2 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease TPR_19 PF14559.6 KNZ81099.1 - 1.8e-09 38.0 0.1 0.0045 17.5 0.0 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ81099.1 - 1.1e-08 35.1 2.1 0.0029 18.3 0.0 5.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ81099.1 - 2e-06 27.5 0.0 0.0093 16.0 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ81099.1 - 7.3e-06 25.6 0.0 0.004 16.9 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ81099.1 - 7.4e-06 26.0 0.3 0.22 11.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ81099.1 - 1.8e-05 25.3 0.0 0.31 11.7 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ81099.1 - 5.8e-05 22.7 0.0 0.0049 16.5 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 KNZ81099.1 - 0.00022 21.2 0.0 0.092 13.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ81099.1 - 0.0022 17.2 0.2 0.04 13.1 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ81099.1 - 0.0039 17.5 0.0 0.74 10.3 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ81099.1 - 0.025 15.2 2.0 8.2 7.3 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 KNZ81099.1 - 0.029 14.8 0.0 11 6.5 0.0 3.1 1 1 1 3 3 3 0 Bacterial transcriptional activator domain La_HTH_kDCL PF18177.1 KNZ81099.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain CotJB PF12652.7 KNZ81099.1 - 0.11 12.8 0.1 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 CotJB protein TPR_7 PF13176.6 KNZ81099.1 - 0.11 12.6 0.3 2.4 8.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DHHA2 PF02833.14 KNZ81100.1 - 1.3e-26 93.5 0.2 3.5e-26 92.1 0.2 1.7 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 KNZ81100.1 - 1.7e-09 37.8 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 DHH family Ntox47 PF15540.6 KNZ81101.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 47 DUF1618 PF07762.14 KNZ81101.1 - 0.41 11.3 2.0 1.3 9.6 2.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1618) SRCR PF00530.18 KNZ81102.1 - 0.13 12.8 0.6 0.31 11.6 0.3 1.9 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain Herpes_pp85 PF04637.12 KNZ81105.1 - 0.045 12.2 0.2 0.066 11.6 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3895 PF13034.6 KNZ81105.1 - 0.081 12.9 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3895) zf-CCHC PF00098.23 KNZ81105.1 - 0.095 12.8 1.4 0.19 11.9 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ81105.1 - 0.41 10.4 3.1 0.74 9.6 3.1 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger DUF3123 PF11321.8 KNZ81105.1 - 1.7 9.4 9.2 3.9 8.2 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) gag-asp_proteas PF13975.6 KNZ81106.1 - 4.9e-06 27.0 0.0 7.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81106.1 - 5.8e-06 26.9 0.0 1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ81106.1 - 0.0035 17.1 0.1 0.0052 16.6 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.8 KNZ81106.1 - 0.046 13.3 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 Ty3 transposon peptidase DUF3913 PF13052.6 KNZ81106.1 - 0.11 12.8 0.1 7 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3913) RT_RNaseH PF17917.1 KNZ81107.1 - 7.1e-10 39.1 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ81107.1 - 2.3e-08 34.0 0.0 4.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve PF00665.26 KNZ81107.1 - 0.0091 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain DUF1919 PF08942.10 KNZ81107.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) gag-asp_proteas PF13975.6 KNZ81109.1 - 0.00025 21.5 0.0 0.00027 21.4 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81109.1 - 0.0011 19.6 0.0 0.0017 19.0 0.0 1.3 1 1 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.23 KNZ81110.1 - 0.093 12.9 0.8 0.093 12.9 0.8 2.1 2 0 0 2 2 2 0 Zinc knuckle Peptidase_S41 PF03572.18 KNZ81111.1 - 0.00038 20.1 0.0 0.00094 18.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 WD40 PF00400.32 KNZ81112.1 - 0.00014 22.5 1.2 0.46 11.4 0.0 5.7 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ81112.1 - 0.00066 19.9 0.1 1.2 9.5 0.0 4.5 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Borrelia_orfX PF04160.12 KNZ81112.1 - 0.059 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Orf-X protein TBCC PF07986.12 KNZ81114.1 - 2.5e-24 85.3 0.2 4.1e-24 84.6 0.2 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KNZ81114.1 - 2.2e-08 34.5 1.5 4.7e-08 33.5 1.5 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Fungal_trans PF04082.18 KNZ81115.1 - 0.022 13.8 0.1 0.022 13.8 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain gpW PF02831.15 KNZ81116.1 - 0.23 11.4 1.8 1.3 9.0 1.8 2.0 1 1 0 1 1 1 0 gpW HSP20 PF00011.21 KNZ81117.1 - 6.3e-07 29.5 0.0 0.043 14.0 0.0 2.7 2 1 0 2 2 2 2 Hsp20/alpha crystallin family CSTF2_hinge PF14327.6 KNZ81118.1 - 8.6e-29 99.8 5.3 2.1e-28 98.6 5.3 1.7 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 KNZ81118.1 - 2e-19 69.2 0.0 3.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 KNZ81118.1 - 2.9e-13 49.2 2.3 7.7e-13 47.8 2.3 1.8 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal tRNA-synt_2b PF00587.25 KNZ81119.1 - 2.8e-34 118.6 0.0 5.4e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KNZ81119.1 - 8.1e-18 64.4 0.3 3.8e-17 62.2 0.2 2.1 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KNZ81119.1 - 6.2e-12 45.4 0.0 1.3e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KNZ81119.1 - 7.6e-11 41.9 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Pkinase PF00069.25 KNZ81120.1 - 9.1e-18 64.6 0.0 4.1e-17 62.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 KNZ81120.1 - 6.4e-17 61.6 8.2 1.2e-07 32.3 0.4 6.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.22 KNZ81120.1 - 5.6e-14 51.0 9.6 0.0011 19.1 0.1 5.8 5 0 0 5 5 5 4 HEAT repeat Pkinase_Tyr PF07714.17 KNZ81120.1 - 4.3e-09 36.0 0.0 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.6 KNZ81120.1 - 2e-06 28.1 0.2 0.12 12.8 0.2 3.8 2 2 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 KNZ81120.1 - 0.0012 18.9 6.3 2.2 8.3 0.7 3.9 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KNZ81120.1 - 0.0036 17.8 1.0 2.5 8.8 0.1 3.0 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KNZ81120.1 - 0.012 16.1 1.2 3.5 8.2 0.1 3.5 3 0 0 3 3 3 0 HEAT-like repeat Cohesin_HEAT PF12765.7 KNZ81120.1 - 0.078 13.3 1.4 4.6 7.6 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Tti2 PF10521.9 KNZ81120.1 - 0.079 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Tti2 family BBS1 PF14779.6 KNZ81120.1 - 0.09 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Adaptin_N PF01602.20 KNZ81120.1 - 0.1 11.2 3.7 1.4 7.4 0.5 2.3 2 0 0 2 2 2 0 Adaptin N terminal region Neocarzinostat PF00960.18 KNZ81120.1 - 0.16 12.0 0.0 0.69 9.9 0.0 2.1 1 0 0 1 1 1 0 Neocarzinostatin family ANAPC4_WD40 PF12894.7 KNZ81120.1 - 0.16 12.3 0.1 4.3 7.7 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ81120.1 - 0.17 10.8 0.5 0.38 9.7 0.2 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RasGEF_N_2 PF14663.6 KNZ81120.1 - 0.22 11.9 0.4 1.6 9.2 0.1 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF1308 PF07000.11 KNZ81121.1 - 0.0001 22.3 0.2 0.053 13.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1308) HSP20 PF00011.21 KNZ81125.1 - 4.4e-23 81.4 0.1 5.9e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ81125.1 - 3.6e-11 42.5 0.0 5.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KNZ81125.1 - 0.002 19.1 0.0 0.0029 18.6 0.0 1.3 1 0 0 1 1 1 1 CS domain FKBP26_C PF18046.1 KNZ81125.1 - 0.033 14.3 0.1 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal Abhydrolase_6 PF12697.7 KNZ81126.1 - 3.7e-08 34.3 3.9 3.8e-08 34.2 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ81126.1 - 3.1e-06 27.0 0.0 6.3e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ81126.1 - 0.0021 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KNZ81126.1 - 0.0051 16.3 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KNZ81126.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.7 KNZ81126.1 - 0.019 13.9 0.0 0.042 12.7 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KNZ81126.1 - 0.058 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.8 KNZ81126.1 - 0.058 12.6 0.0 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) PAF-AH_p_II PF03403.13 KNZ81126.1 - 0.074 11.6 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 KNZ81126.1 - 0.23 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein CBP_BcsO PF17037.5 KNZ81126.1 - 2.7 8.1 6.6 2.2 8.4 3.5 2.3 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsO Abhydrolase_6 PF12697.7 KNZ81127.1 - 8.7e-10 39.6 0.2 1.9e-09 38.4 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ81127.1 - 1.7e-06 27.9 0.0 6.9e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ81127.1 - 0.003 17.1 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ndr PF03096.14 KNZ81127.1 - 0.052 12.2 0.0 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Ndr family Hydrolase_4 PF12146.8 KNZ81127.1 - 0.053 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 KNZ81127.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Epimerase PF01370.21 KNZ81128.1 - 9.4e-10 38.4 0.0 5.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ81128.1 - 1.6e-08 34.7 1.8 4.1e-08 33.3 0.5 2.0 1 1 1 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KNZ81128.1 - 3.7e-05 24.0 0.1 8e-05 22.9 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KNZ81128.1 - 0.0029 16.7 0.1 0.0071 15.4 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KNZ81128.1 - 0.0068 16.0 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KNZ81128.1 - 0.0095 16.2 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 KNZ81128.1 - 0.032 14.3 0.0 0.079 13.0 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KNZ81128.1 - 0.036 14.6 0.1 0.15 12.6 0.0 1.9 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 KNZ81128.1 - 0.083 12.0 0.0 0.46 9.6 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.22 KNZ81129.1 - 4.6e-43 147.6 0.0 5.6e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SAVED PF18145.1 KNZ81129.1 - 0.023 14.5 0.1 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain zf-rbx1 PF12678.7 KNZ81130.1 - 2.8e-24 85.2 12.9 3.8e-24 84.7 12.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KNZ81130.1 - 1.3e-16 60.5 9.5 1.6e-16 60.1 9.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KNZ81130.1 - 5.2e-06 26.7 15.0 0.00015 22.1 15.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KNZ81130.1 - 2.3e-05 24.1 2.7 2.3e-05 24.1 2.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KNZ81130.1 - 0.0011 18.8 11.0 0.011 15.6 11.0 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KNZ81130.1 - 0.093 12.6 10.2 0.29 11.0 3.9 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KNZ81130.1 - 0.28 11.3 7.1 1 9.4 7.1 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KNZ81130.1 - 0.39 10.9 9.7 2 8.6 9.9 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KNZ81130.1 - 0.58 9.8 14.5 0.1 12.2 4.5 2.4 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 KNZ81130.1 - 2.7 7.8 18.1 1.6e+02 2.2 18.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger Fmp27_WPPW PF10359.9 KNZ81131.1 - 2.7 6.7 13.7 8.5 5.1 13.7 1.9 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HSP20 PF00011.21 KNZ81132.1 - 6.1e-23 80.9 0.1 8.2e-23 80.5 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ81132.1 - 8.4e-12 44.5 0.0 1.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KNZ81132.1 - 0.002 19.1 0.0 0.003 18.5 0.0 1.3 1 0 0 1 1 1 1 CS domain FKBP26_C PF18046.1 KNZ81132.1 - 0.038 14.1 0.1 4.3 7.5 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal HSP20 PF00011.21 KNZ81133.1 - 7.5e-23 80.6 0.0 9.7e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ81133.1 - 6.3e-12 44.9 0.0 9.4e-12 44.3 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KNZ81133.1 - 0.0017 19.3 0.0 0.0025 18.8 0.0 1.3 1 0 0 1 1 1 1 CS domain FKBP26_C PF18046.1 KNZ81133.1 - 0.021 14.9 0.0 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal DUF4097 PF13349.6 KNZ81133.1 - 0.028 13.8 0.1 0.28 10.5 0.2 1.9 1 1 1 2 2 2 0 Putative adhesin HSP20 PF00011.21 KNZ81134.1 - 7.6e-23 80.6 0.1 1e-22 80.2 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ81134.1 - 3.9e-11 42.3 0.0 6.4e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 KNZ81134.1 - 0.0022 19.0 0.0 0.0031 18.5 0.0 1.3 1 0 0 1 1 1 1 CS domain FKBP26_C PF18046.1 KNZ81134.1 - 0.039 14.0 0.1 4.2 7.5 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal Piwi PF02171.17 KNZ81136.1 - 6.4e-83 278.5 0.0 9.4e-83 277.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KNZ81136.1 - 7.7e-25 88.1 0.1 2.2e-24 86.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KNZ81136.1 - 1.4e-20 72.6 0.2 3.6e-20 71.4 0.2 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KNZ81136.1 - 1.7e-15 57.1 0.0 2.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 KNZ81136.1 - 6.8e-14 51.9 0.2 2.3e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 KNZ81136.1 - 0.00049 20.3 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ApbA PF02558.16 KNZ81137.1 - 1.5e-15 57.2 0.0 2.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KNZ81137.1 - 7.3e-15 55.3 0.0 3.2e-12 46.7 0.0 2.5 1 1 1 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal IlvN PF07991.12 KNZ81137.1 - 0.068 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 KNZ81137.1 - 0.14 12.4 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 KNZ81137.1 - 0.21 10.8 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain mRNA_triPase PF02940.15 KNZ81137.1 - 0.25 11.0 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, beta chain ThiF PF00899.21 KNZ81137.1 - 1.9 7.8 3.4 0.64 9.3 0.3 1.7 2 1 0 2 2 2 0 ThiF family Pkinase PF00069.25 KNZ81139.1 - 1.5e-60 204.8 0.0 1.9e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81139.1 - 3.9e-26 91.9 0.0 5.2e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ81139.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Ribonuclease_3 PF00636.26 KNZ81140.1 - 6.9e-15 55.6 3.2 7.8e-09 36.1 0.0 3.2 4 1 0 4 4 4 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KNZ81140.1 - 9e-09 35.6 0.0 1.7e-06 28.2 0.0 2.6 2 1 0 2 2 2 2 Ribonuclease-III-like SARS_lipid_bind PF09399.10 KNZ81143.1 - 0.17 12.1 0.0 0.46 10.7 0.0 1.7 1 1 0 1 1 1 0 SARS lipid binding protein Herpes_Helicase PF02689.14 KNZ81146.1 - 7.9e-07 27.4 0.0 8.3e-07 27.3 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ81146.1 - 0.00053 19.8 0.0 0.0013 18.5 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Nop53 PF07767.11 KNZ81147.1 - 0.035 13.5 7.4 0.066 12.6 7.4 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Retrotran_gag_2 PF14223.6 KNZ81148.1 - 2.8e-12 46.5 0.5 4e-12 46.0 0.5 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ81148.1 - 3.7e-05 23.3 0.6 9.1e-05 22.1 0.6 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger TolA_bind_tri PF16331.5 KNZ81148.1 - 0.045 13.8 0.3 0.045 13.8 0.3 1.7 2 0 0 2 2 2 0 TolA binding protein trimerisation ZapA PF05164.13 KNZ81148.1 - 0.087 13.3 3.7 0.27 11.7 3.6 2.0 1 1 0 1 1 1 0 Cell division protein ZapA NAPRTase_N PF17767.1 KNZ81148.1 - 0.12 12.8 0.6 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Peptidase_C98 PF15499.6 KNZ81148.1 - 0.13 11.7 3.6 0.23 10.9 3.4 1.6 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF1054 PF06335.12 KNZ81148.1 - 0.62 10.0 3.9 1.2 9.0 1.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1054) Arm PF00514.23 KNZ81149.1 - 2.2e-12 46.5 5.3 0.0049 16.9 0.0 5.8 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KNZ81149.1 - 3.6e-10 39.2 7.3 0.00014 21.8 0.2 5.7 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 KNZ81149.1 - 3e-07 30.8 6.9 0.04 14.5 0.0 5.4 5 0 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 KNZ81149.1 - 3.9e-05 24.0 7.9 0.87 10.0 0.0 4.9 4 1 0 4 4 4 2 HEAT repeats DUF3361 PF11841.8 KNZ81149.1 - 0.0054 16.7 0.0 0.77 9.7 0.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF3361) Maff2 PF12750.7 KNZ81149.1 - 0.44 10.4 3.6 2.1 8.2 0.1 3.0 4 0 0 4 4 4 0 Maff2 family PIF1 PF05970.14 KNZ81150.1 - 8.9e-10 38.3 0.0 8.9e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ81150.1 - 0.0003 20.6 0.0 0.00039 20.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain gag-asp_proteas PF13975.6 KNZ81153.1 - 0.0025 18.3 0.0 0.0059 17.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81153.1 - 0.061 14.0 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 KNZ81154.1 - 3.9e-37 128.0 0.4 6.8e-35 120.7 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81154.1 - 3.2e-17 62.7 0.0 4.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ81154.1 - 1.4e-05 24.6 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Spc7 PF08317.11 KNZ81155.1 - 0.005 15.8 15.4 0.005 15.8 15.4 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein CVNH PF08881.10 KNZ81155.1 - 0.013 16.1 1.8 0.86 10.3 0.5 2.8 1 1 1 2 2 2 0 CVNH domain APG6_N PF17675.1 KNZ81155.1 - 0.97 10.0 38.2 5.6 7.5 0.9 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region Sas6_CC PF18594.1 KNZ81155.1 - 2.7 7.8 6.7 2.7 7.9 1.6 3.4 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain FPP PF05911.11 KNZ81155.1 - 3.8 5.6 38.4 3.9 5.5 37.1 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil tRNA-synt_1c PF00749.21 KNZ81156.1 - 0.077 11.9 11.1 0.19 10.6 2.3 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain GREB1 PF15782.5 KNZ81156.1 - 3 4.9 10.9 3.3 4.7 10.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dicty_REP PF05086.12 KNZ81156.1 - 5.3 4.9 9.6 6.6 4.6 9.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RBM39linker PF15519.6 KNZ81156.1 - 7.1 7.8 13.1 4.6 8.4 3.4 2.3 1 1 1 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein HIP1_clath_bdg PF16515.5 KNZ81157.1 - 0.31 11.7 12.0 1.2 9.8 0.7 2.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PIF1 PF05970.14 KNZ81158.1 - 2.3e-39 135.6 0.0 2.6e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ81158.1 - 0.0014 18.4 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ81158.1 - 0.0031 17.6 0.0 0.008 16.2 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ81158.1 - 0.0084 16.5 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ81158.1 - 0.011 15.5 0.1 0.025 14.3 0.1 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KNZ81158.1 - 0.03 13.9 0.2 0.042 13.4 0.2 1.3 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ81158.1 - 0.065 13.6 0.1 0.36 11.2 0.1 2.1 1 1 0 1 1 1 0 RNA helicase DUF2791 PF10923.8 KNZ81158.1 - 0.13 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Torsin PF06309.11 KNZ81158.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA PF00004.29 KNZ81158.1 - 0.19 12.2 0.2 2.5 8.5 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-RVT PF13966.6 KNZ81159.1 - 0.0021 18.8 5.1 0.0027 18.4 2.2 2.1 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase Retrotran_gag_2 PF14223.6 KNZ81160.1 - 2.1e-06 27.5 0.1 7.2e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type Mg_trans_NIPA PF05653.14 KNZ81161.1 - 1.8e-23 83.1 6.6 2.5e-23 82.6 6.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA HEAT_EZ PF13513.6 KNZ81162.1 - 2e-07 31.4 5.8 0.00024 21.5 0.0 4.3 5 0 0 5 5 5 3 HEAT-like repeat Sulfatase PF00884.23 KNZ81163.1 - 0.049 13.0 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Sulfatase SNF2_N PF00176.23 KNZ81164.1 - 6e-37 127.2 0.6 9.2e-37 126.6 0.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 KNZ81164.1 - 0.0007 19.4 8.2 0.0007 19.4 8.2 3.0 2 1 1 3 3 3 1 PHD-finger Helicase_C PF00271.31 KNZ81164.1 - 0.0022 18.3 0.0 0.26 11.7 0.0 3.2 2 1 1 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KNZ81164.1 - 0.025 13.8 0.0 0.067 12.3 0.0 1.6 1 1 1 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 GP41 PF00517.17 KNZ81164.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral envelope protein Imm52 PF15579.6 KNZ81164.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 52 RINGv PF12906.7 KNZ81165.1 - 8.5e-09 35.4 2.4 1.1e-08 35.0 2.4 1.2 1 0 0 1 1 1 1 RING-variant domain Peptidase_M28 PF04389.17 KNZ81166.1 - 1.2e-29 103.4 0.3 2.4e-29 102.5 0.3 1.4 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 KNZ81166.1 - 5.4e-07 29.5 0.1 9.9e-07 28.7 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 KNZ81166.1 - 0.0089 15.1 0.0 0.04 12.9 0.0 1.8 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase F-box-like PF12937.7 KNZ81168.1 - 9.8e-06 25.4 0.1 3.3e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 KNZ81168.1 - 0.19 12.2 0.3 0.19 12.2 0.3 6.0 5 2 2 7 7 7 0 Leucine Rich repeats (2 copies) APH PF01636.23 KNZ81170.1 - 1e-06 28.8 0.0 2.6e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CCDC53 PF10152.9 KNZ81171.1 - 0.0055 17.1 2.6 0.0084 16.5 2.6 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex FliS PF02561.14 KNZ81171.1 - 0.024 14.9 0.4 0.047 14.0 0.4 1.5 1 0 0 1 1 1 0 Flagellar protein FliS Tropomyosin_1 PF12718.7 KNZ81171.1 - 0.027 14.6 0.3 0.046 13.9 0.3 1.4 1 0 0 1 1 1 0 Tropomyosin like SKA1 PF07160.12 KNZ81171.1 - 0.035 14.0 4.7 0.043 13.7 4.7 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF1366 PF07104.11 KNZ81171.1 - 0.042 13.6 0.6 0.079 12.7 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Allexi_40kDa PF05549.11 KNZ81171.1 - 0.05 13.1 1.6 0.07 12.6 1.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein His_Phos_1 PF00300.22 KNZ81171.1 - 0.078 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) SlyX PF04102.12 KNZ81171.1 - 0.19 12.3 2.7 5.2 7.8 0.3 2.3 1 1 1 2 2 2 0 SlyX Pol_alpha_B_N PF08418.10 KNZ81171.1 - 0.68 9.9 8.7 0.22 11.5 0.4 2.1 1 1 1 2 2 2 0 DNA polymerase alpha subunit B N-terminal Ank_2 PF12796.7 KNZ81172.1 - 1.5e-61 205.0 35.9 6.9e-16 58.6 4.2 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ81172.1 - 5.7e-52 173.5 30.2 8.2e-13 48.6 1.8 5.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ81172.1 - 2.7e-40 135.9 31.3 2e-11 43.9 3.7 5.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ81172.1 - 2.8e-31 104.0 15.7 1.2e-05 25.3 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 KNZ81172.1 - 1.9e-30 103.9 27.7 2.7e-06 27.5 0.4 6.7 6 0 0 6 6 6 5 Ankyrin repeat Amidohydro_1 PF01979.20 KNZ81172.1 - 0.052 12.8 2.6 0.088 12.1 2.6 1.3 1 0 0 1 1 1 0 Amidohydrolase family DUF3797 PF12677.7 KNZ81172.1 - 1.1 9.2 4.9 3.7 7.5 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) DUF1110 PF06533.12 KNZ81172.1 - 1.3 9.0 6.3 24 4.8 0.1 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1110) Cys_Met_Meta_PP PF01053.20 KNZ81173.1 - 1.8e-121 405.3 0.0 3.5e-91 305.6 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KNZ81173.1 - 0.041 13.0 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II HsbA PF12296.8 KNZ81174.1 - 0.00086 19.7 0.0 0.0018 18.7 0.0 1.6 1 1 0 1 1 1 1 Hydrophobic surface binding protein A MatE PF01554.18 KNZ81176.1 - 1.3e-18 67.2 8.3 1.6e-17 63.6 5.0 2.5 2 0 0 2 2 2 2 MatE PLDc_2 PF13091.6 KNZ81177.1 - 1.8e-16 60.2 0.1 1.1e-06 28.6 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 KNZ81177.1 - 3.3e-14 52.4 3.4 5.4e-08 32.7 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Aldo_ket_red PF00248.21 KNZ81179.1 - 8.3e-35 120.4 0.4 2e-33 115.9 0.4 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Gag_p19 PF02228.16 KNZ81179.1 - 0.03 14.7 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 Major core protein p19 HTH_10 PF04967.12 KNZ81179.1 - 0.13 12.1 0.0 13 5.7 0.0 3.3 4 0 0 4 4 4 0 HTH DNA binding domain Pro_isomerase PF00160.21 KNZ81180.1 - 2.8e-47 160.9 0.1 3.2e-47 160.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RVT_1 PF00078.27 KNZ81182.1 - 0.029 13.9 0.3 0.031 13.8 0.3 1.0 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GMC_oxred_N PF00732.19 KNZ81183.1 - 9.9e-63 212.3 0.0 1.4e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ81183.1 - 3.9e-27 95.5 0.0 7.8e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KNZ81183.1 - 2.4e-06 26.8 0.1 4.1e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KNZ81183.1 - 0.00061 19.1 0.1 0.0025 17.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 KNZ81183.1 - 0.0032 16.6 0.2 0.058 12.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KNZ81183.1 - 0.026 13.7 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KNZ81183.1 - 0.035 13.2 0.1 0.97 8.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 KNZ81183.1 - 0.096 11.4 0.6 0.16 10.7 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein PIP5K PF01504.18 KNZ81184.1 - 2.8e-39 135.0 7.1 1.3e-31 109.8 0.1 2.9 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Homeodomain PF00046.29 KNZ81186.1 - 4.1e-10 39.4 0.1 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Homeodomain adh_short PF00106.25 KNZ81187.1 - 5.2e-26 91.3 0.1 6.2e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ81187.1 - 6.9e-23 81.4 0.1 9.1e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.15 KNZ81187.1 - 0.011 15.6 0.1 0.026 14.4 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.18 KNZ81187.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3813 PF12758.7 KNZ81188.1 - 0.0067 16.7 0.0 0.0098 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3813) SET PF00856.28 KNZ81189.1 - 5.9e-13 49.6 0.0 5.9e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 SET domain VWA PF00092.28 KNZ81190.1 - 4.1e-08 33.7 0.0 5.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KNZ81190.1 - 2.6e-05 24.8 0.1 0.00028 21.5 0.0 2.5 2 1 1 3 3 3 1 von Willebrand factor type A domain Copine PF07002.16 KNZ81190.1 - 7.1e-05 22.4 0.0 0.0002 20.9 0.0 1.8 1 1 1 2 2 2 1 Copine vWA-TerF-like PF10138.9 KNZ81190.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 vWA found in TerF C terminus FlaE PF07559.14 KNZ81190.1 - 0.032 14.8 0.0 0.11 13.1 0.0 1.8 1 1 0 1 1 1 0 Flagellar basal body protein FlaE Helitron_like_N PF14214.6 KNZ81191.1 - 1.9e-64 217.4 0.1 3e-64 216.7 0.1 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.13 KNZ81191.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) MitMem_reg PF13012.6 KNZ81192.1 - 0.032 14.7 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ81193.1 - 2.9e-11 43.2 0.0 3.6e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.6 KNZ81193.1 - 0.00019 21.8 0.0 0.00024 21.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ81193.1 - 0.0008 19.5 0.0 0.00092 19.2 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KNZ81193.1 - 0.0061 16.9 0.0 0.013 15.9 0.0 1.5 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 KNZ81193.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 2 0 0 2 2 2 0 AAA domain DUF2791 PF10923.8 KNZ81193.1 - 0.014 14.2 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_30 PF13604.6 KNZ81193.1 - 0.017 14.8 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ81193.1 - 0.02 15.3 0.5 0.38 11.2 0.1 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KNZ81193.1 - 0.041 14.4 0.0 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 KNZ81193.1 - 0.08 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 KNZ81193.1 - 0.085 12.5 0.1 0.094 12.4 0.1 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.16 KNZ81193.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 KNZ81193.1 - 0.16 12.5 0.9 1.6 9.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 KNZ81194.1 - 0.00016 19.7 0.0 0.00017 19.7 0.0 1.0 1 0 0 1 1 1 1 Helicase Helitron_like_N PF14214.6 KNZ81195.1 - 4.5e-19 69.4 0.1 5.5e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ81195.1 - 0.14 12.1 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Inovirus Gp2 Helitron_like_N PF14214.6 KNZ81196.1 - 1.4e-15 58.1 0.1 3e-15 57.0 0.0 1.6 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus RT_RNaseH_2 PF17919.1 KNZ81197.1 - 1.3e-08 34.8 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ81197.1 - 3.7e-05 24.0 0.1 8.9e-05 22.7 0.0 1.7 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Patatin PF01734.22 KNZ81199.1 - 8.3e-15 55.5 0.0 4.2e-14 53.2 0.0 2.1 2 1 0 2 2 2 1 Patatin-like phospholipase Mqo PF06039.15 KNZ81199.1 - 0.0068 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) ocr PF08684.10 KNZ81199.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 DNA mimic ocr RicinB_lectin_2 PF14200.6 KNZ81201.1 - 1.5e-06 28.9 0.2 2.1e-05 25.2 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like p450 PF00067.22 KNZ81202.1 - 9.8e-52 176.2 3.1 2.1e-31 109.2 0.2 3.0 3 0 0 3 3 3 3 Cytochrome P450 DJ-1_PfpI PF01965.24 KNZ81203.1 - 2e-10 40.7 0.0 2.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family RVT_2 PF07727.14 KNZ81205.1 - 0.0011 18.6 0.1 0.015 15.0 0.0 2.5 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.6 KNZ81205.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like p450 PF00067.22 KNZ81206.1 - 8.4e-74 249.0 0.0 1e-73 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TBPIP PF07106.13 KNZ81209.1 - 7.9e-18 64.2 0.2 1.2e-17 63.5 0.2 1.3 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 KNZ81209.1 - 0.00039 20.8 0.0 0.00076 19.8 0.0 1.5 1 1 0 1 1 1 1 Penicillinase repressor Med4 PF10018.9 KNZ81209.1 - 0.042 13.5 0.2 0.066 12.9 0.2 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HTH_IclR PF09339.10 KNZ81209.1 - 0.079 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain z-alpha PF02295.17 KNZ81209.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain Mito_carr PF00153.27 KNZ81210.1 - 1.3e-57 191.7 1.9 7.1e-23 80.4 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KNZ81210.1 - 0.00098 18.4 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Fungal_trans PF04082.18 KNZ81211.1 - 5.1e-12 45.4 0.0 8.4e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_4 PF13637.6 KNZ81212.1 - 2.8e-19 69.2 1.1 1.5e-09 38.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ81212.1 - 2.1e-17 63.5 0.1 8.8e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ81212.1 - 7.8e-16 57.9 1.4 3.1e-06 27.4 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ81212.1 - 1.5e-14 52.7 0.5 6.5e-05 23.0 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 KNZ81212.1 - 1.9e-14 53.4 4.3 5.5e-07 29.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 KNZ81213.1 - 3.6e-08 33.1 0.0 5.4e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81213.1 - 0.081 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KNZ81216.1 - 2.8e-06 26.9 0.0 0.0056 16.1 0.0 2.5 1 1 0 2 2 2 2 Protein kinase domain Prominin PF05478.11 KNZ81217.1 - 0.0025 15.9 0.4 0.0032 15.5 0.4 1.1 1 0 0 1 1 1 1 Prominin Pkinase PF00069.25 KNZ81218.1 - 1.7e-09 37.4 0.0 8.7e-07 28.6 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81218.1 - 0.00085 18.7 0.0 0.13 11.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ81219.1 - 0.0019 17.6 0.5 0.09 12.1 0.4 2.8 2 2 1 3 3 3 1 Protein kinase domain LRR_adjacent PF08191.11 KNZ81219.1 - 0.13 12.4 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 LRR adjacent Evr1_Alr PF04777.13 KNZ81220.1 - 1.4e-19 70.4 0.1 1.9e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family OPT PF03169.15 KNZ81221.1 - 1e-180 602.5 39.8 1.7e-180 601.7 39.8 1.4 1 1 0 1 1 1 1 OPT oligopeptide transporter protein LSM PF01423.22 KNZ81222.1 - 1.3e-16 60.1 0.0 1.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain TP_methylase PF00590.20 KNZ81224.1 - 1.5e-18 67.6 0.0 2.5e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases tRNA-synt_2 PF00152.20 KNZ81225.1 - 6.5e-86 288.3 0.0 8.9e-86 287.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KNZ81225.1 - 7e-12 45.2 0.1 1.3e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain COesterase PF00135.28 KNZ81226.1 - 8.4e-66 222.9 0.0 2.6e-55 188.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ81226.1 - 4.6e-07 29.9 0.1 2.6e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ81226.1 - 0.0014 19.3 3.4 0.0042 17.7 3.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 KNZ81226.1 - 0.047 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KNZ81226.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KNZ81227.1 - 4e-145 484.6 0.0 2.3e-69 234.6 0.0 4.0 3 1 1 4 4 4 4 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ81227.1 - 8.1e-19 68.3 0.1 9.7e-09 35.4 0.0 3.6 2 2 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ81227.1 - 8.7e-05 22.1 0.2 0.38 10.2 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 KNZ81227.1 - 0.0023 18.5 10.7 0.2 12.2 1.0 3.5 3 2 0 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ81227.1 - 0.0048 16.2 0.0 0.82 8.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 KNZ81227.1 - 0.088 11.7 0.1 4.9 5.9 0.0 2.5 2 2 0 2 2 2 0 Steryl acetyl hydrolase Esterase_phd PF10503.9 KNZ81227.1 - 0.098 12.1 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Mito_carr PF00153.27 KNZ81228.1 - 6e-41 138.3 0.2 1e-13 51.0 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein 3HCDH_N PF02737.18 KNZ81229.1 - 2.5e-48 164.4 2.0 1e-47 162.3 2.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KNZ81229.1 - 6.8e-22 77.9 0.0 1.6e-21 76.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KNZ81229.1 - 0.0029 17.8 0.2 0.0075 16.4 0.2 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KNZ81229.1 - 0.055 12.8 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 KNZ81230.1 - 7.4e-09 35.3 0.0 1.5e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81230.1 - 6.1e-05 22.4 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sulfate_transp PF00916.20 KNZ81232.1 - 4.2e-82 275.9 19.8 4.2e-82 275.9 19.8 1.7 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 KNZ81232.1 - 1.8e-18 66.2 0.0 6.1e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 KNZ81232.1 - 5.7e-05 23.4 0.0 0.00019 21.7 0.0 2.0 1 0 0 1 1 1 1 STAS domain Cyclase PF04199.13 KNZ81233.1 - 4.7e-35 120.8 0.0 5.9e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Peptidase_S8 PF00082.22 KNZ81234.1 - 2.1e-34 119.1 5.0 4e-34 118.2 5.0 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KNZ81234.1 - 1.4e-13 51.3 0.1 2.7e-13 50.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acetyltransf_1 PF00583.25 KNZ81235.1 - 1.7e-08 34.7 0.1 2.9e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KNZ81235.1 - 1.9e-06 27.8 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ81235.1 - 2.6e-06 27.3 0.0 5.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KNZ81235.1 - 7.3e-05 23.5 0.1 0.00021 22.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KNZ81235.1 - 0.0002 21.7 0.1 0.00039 20.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SET PF00856.28 KNZ81236.1 - 8.5e-08 32.8 0.0 2.9e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 KNZ81237.1 - 8.9e-68 228.5 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81237.1 - 1.2e-34 119.8 0.0 1.5e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ81237.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3627 PF12299.8 KNZ81237.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) SNF2_N PF00176.23 KNZ81238.1 - 5.4e-63 212.8 0.1 1.1e-62 211.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KNZ81238.1 - 1.8e-17 63.7 0.0 1.6e-15 57.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNZ81238.1 - 0.00011 22.0 0.0 0.00035 20.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.13 KNZ81238.1 - 0.011 16.0 2.6 0.014 15.7 0.3 2.5 2 0 0 2 2 2 0 HSA MSA-2c PF12238.8 KNZ81238.1 - 0.015 15.4 1.0 0.097 12.7 0.1 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Mito_carr PF00153.27 KNZ81240.1 - 2.4e-66 219.7 2.0 1.3e-22 79.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TEBP_beta PF07404.11 KNZ81240.1 - 0.18 11.1 0.1 0.35 10.2 0.1 1.4 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) FSH1 PF03959.13 KNZ81241.1 - 1.3e-58 198.2 0.0 1.5e-58 198.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KNZ81241.1 - 0.0018 18.9 0.7 0.0086 16.7 0.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KNZ81241.1 - 0.005 16.5 0.0 5.8 6.5 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ81241.1 - 0.051 12.8 0.0 1.8 7.8 0.0 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 HEAT_EZ PF13513.6 KNZ81242.1 - 9.4e-30 102.6 14.9 2.6e-14 53.3 0.0 10.3 9 3 2 11 11 11 5 HEAT-like repeat HEAT PF02985.22 KNZ81242.1 - 4.9e-19 66.8 20.2 0.00082 19.4 0.0 10.1 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 KNZ81242.1 - 1.7e-15 57.1 1.3 2.1e-05 24.8 0.0 7.6 6 4 2 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 KNZ81242.1 - 5.7e-09 36.5 0.2 0.0054 17.3 0.0 4.7 4 2 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KNZ81242.1 - 3.9e-07 30.3 0.2 0.0051 16.9 0.0 4.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 KNZ81242.1 - 8.3e-06 26.0 0.4 0.052 13.9 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 KNZ81242.1 - 5.4e-05 23.1 1.2 4.7 7.4 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 KNZ81242.1 - 5.7e-05 22.9 0.0 0.00036 20.4 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3437 PF11919.8 KNZ81242.1 - 0.041 13.8 0.6 32 4.5 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) CLASP_N PF12348.8 KNZ81242.1 - 0.058 12.9 0.1 20 4.6 0.0 3.9 4 1 1 5 5 5 0 CLASP N terminal Tti2 PF10521.9 KNZ81242.1 - 0.066 12.7 0.3 28 4.1 0.1 3.6 3 1 1 4 4 4 0 Tti2 family Adaptin_N PF01602.20 KNZ81242.1 - 0.067 11.7 1.3 0.33 9.5 0.1 2.6 3 0 0 3 3 3 0 Adaptin N terminal region RTP1_C1 PF10363.9 KNZ81242.1 - 0.12 12.6 0.1 1.2 9.3 0.0 2.6 3 0 0 3 3 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Lectin_leg-like PF03388.13 KNZ81243.1 - 3.2e-53 180.4 0.6 1.3e-52 178.4 0.6 1.8 1 1 0 1 1 1 1 Legume-like lectin family T2SSM_b PF10741.9 KNZ81244.1 - 0.021 14.6 0.3 0.081 12.7 0.1 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Arm-DNA-bind_5 PF17293.2 KNZ81244.1 - 0.1 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Pkinase PF00069.25 KNZ81246.1 - 1.5e-11 44.2 0.0 1.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81246.1 - 8.3e-05 22.0 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 KNZ81247.1 - 3.7e-09 36.3 0.0 2.9e-06 26.9 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Seadorna_VP7 PF07387.11 KNZ81247.1 - 0.0022 17.1 0.3 0.0035 16.5 0.3 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_Tyr PF07714.17 KNZ81247.1 - 0.0029 16.9 0.0 0.18 11.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Flavokinase PF01687.17 KNZ81248.1 - 5e-24 84.7 0.0 6.6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase Cerato-platanin PF07249.12 KNZ81249.1 - 2e-40 137.6 0.2 2.3e-40 137.4 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin LRR_4 PF12799.7 KNZ81250.1 - 0.02 15.3 0.0 6.2 7.4 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Herpes_Helicase PF02689.14 KNZ81251.1 - 4.6e-05 21.6 0.0 4.8e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ81251.1 - 0.11 12.3 0.2 0.25 11.2 0.1 1.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain DNA_repr_REX1B PF14966.6 KNZ81252.1 - 0.083 13.6 0.3 0.12 13.1 0.3 1.3 1 0 0 1 1 1 0 DNA repair REX1-B Pkinase PF00069.25 KNZ81253.1 - 7.3e-11 41.9 0.0 2.7e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81253.1 - 0.00059 19.2 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KNZ81253.1 - 0.036 14.0 0.1 2.5 7.9 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ81253.1 - 0.076 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_binding_5 PF07994.12 KNZ81254.1 - 3.2e-140 467.1 0.0 3.8e-140 466.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KNZ81254.1 - 2.4e-45 153.2 0.0 4.3e-45 152.5 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF4203 PF13886.6 KNZ81255.1 - 2e-16 60.3 18.3 2.5e-16 60.0 18.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3742 PF12553.8 KNZ81255.1 - 2.8 8.1 4.8 3.3 7.8 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) ER_lumen_recept PF00810.18 KNZ81256.1 - 8.7e-56 188.8 6.2 1.6e-55 188.0 6.2 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 KNZ81256.1 - 0.00028 20.6 5.4 0.54 10.1 0.1 4.3 3 1 1 4 4 4 2 PQ loop repeat Copper-fist PF00649.18 KNZ81257.1 - 2.8 7.5 10.6 13 5.3 4.9 2.8 1 1 1 2 2 2 0 Copper fist DNA binding domain Exo_endo_phos_2 PF14529.6 KNZ81258.1 - 5.3e-09 36.0 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-RVT PF13966.6 KNZ81258.1 - 3.3e-07 30.9 0.1 8.6e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.24 KNZ81258.1 - 4.4e-07 30.2 0.0 2e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 KNZ81258.1 - 0.00035 20.2 0.1 0.00073 19.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family APH PF01636.23 KNZ81259.1 - 1.1e-07 32.0 0.1 3.3e-05 23.9 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ81259.1 - 0.026 14.1 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase PQQ_3 PF13570.6 KNZ81261.1 - 0.00042 20.7 0.0 27 5.4 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 KNZ81261.1 - 0.0033 17.1 0.0 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 KNZ81261.1 - 0.019 15.3 0.0 10 6.5 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KNZ81261.1 - 0.04 13.9 0.0 8.6 6.5 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat WD40_like PF17005.5 KNZ81261.1 - 0.041 13.2 0.7 0.95 8.7 0.2 2.4 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 KNZ81261.1 - 0.12 13.3 1.1 0.8 10.7 0.0 2.9 2 1 0 2 2 2 0 WD domain, G-beta repeat GGDEF_2 PF17853.1 KNZ81262.1 - 0.096 12.9 0.8 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 GGDEF-like domain Integrase_H2C2 PF17921.1 KNZ81263.1 - 1.6e-14 53.7 0.2 2.7e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain tRNA_bind PF01588.20 KNZ81265.1 - 2.2e-26 91.8 0.0 3.8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 KNZ81265.1 - 0.00038 20.6 0.6 0.0012 19.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KNZ81265.1 - 0.00065 19.8 0.7 0.0013 18.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNZ81265.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 KNZ81265.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1764 PF08576.10 KNZ81265.1 - 0.5 11.3 4.9 0.19 12.7 1.7 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ribosomal_L6 PF00347.23 KNZ81267.1 - 7e-23 81.1 0.0 2.6e-11 44.0 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 DIOX_N PF14226.6 KNZ81268.1 - 1e-24 87.5 0.0 1.6e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KNZ81268.1 - 1.5e-15 57.5 0.0 2.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.23 KNZ81269.1 - 0.0045 17.2 0.0 0.027 14.7 0.0 2.1 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TetR_C_7 PF14246.6 KNZ81269.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain FEZ PF07763.13 KNZ81269.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein Alanine_zipper PF11839.8 KNZ81270.1 - 2.7e-08 34.1 87.4 1.2 9.5 11.6 6.2 1 1 5 6 6 6 6 Alanine-zipper, major outer membrane lipoprotein DUF1325 PF07039.11 KNZ81272.1 - 5.8e-37 126.7 0.0 1e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain Translin PF01997.16 KNZ81273.1 - 3.4e-50 170.9 0.1 3.9e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Translin family Cu_amine_oxidN1 PF07833.11 KNZ81273.1 - 0.095 13.2 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain Rx_N PF18052.1 KNZ81273.1 - 0.14 12.4 3.6 0.28 11.5 1.4 2.3 2 1 0 2 2 2 0 Rx N-terminal domain SEN1_N PF12726.7 KNZ81274.1 - 3.9e-145 485.0 0.5 5.4e-145 484.5 0.5 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KNZ81274.1 - 4.3e-67 226.6 0.8 8.2e-67 225.7 0.8 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KNZ81274.1 - 9.5e-60 201.6 0.0 2.1e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ81274.1 - 2.9e-11 43.9 0.0 5.9e-09 36.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ81274.1 - 1.8e-09 37.6 0.1 2.4e-05 24.1 0.0 2.7 2 1 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 KNZ81274.1 - 0.0003 20.4 1.1 0.024 14.2 0.6 2.7 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KNZ81274.1 - 0.00036 20.4 2.2 4.2 7.0 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KNZ81274.1 - 0.0087 15.8 0.2 0.024 14.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.6 KNZ81274.1 - 0.014 15.8 0.2 0.071 13.5 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KNZ81274.1 - 0.014 14.4 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 KNZ81274.1 - 0.018 14.6 0.1 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KNZ81274.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 KNZ81274.1 - 0.051 14.0 1.2 0.22 11.9 1.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KNZ81274.1 - 0.11 12.8 0.4 0.88 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 KNZ81274.1 - 0.16 11.8 1.1 2.6 7.9 0.1 2.6 2 1 0 2 2 2 0 Helicase Atg14 PF10186.9 KNZ81274.1 - 0.35 9.9 6.8 0.64 9.0 5.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IMUP PF15761.5 KNZ81274.1 - 2.5 8.8 13.4 0.04 14.6 4.5 2.7 2 0 0 2 2 1 0 Immortalisation up-regulated protein ALG11_N PF15924.5 KNZ81275.1 - 3.2e-86 288.7 0.8 4.5e-86 288.2 0.8 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KNZ81275.1 - 6.5e-22 77.9 0.0 1e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KNZ81275.1 - 4.4e-10 40.1 0.0 1.1e-09 38.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 KNZ81275.1 - 0.00082 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KNZ81275.1 - 0.0061 16.6 0.0 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Vg_Tdu PF07545.14 KNZ81275.1 - 0.093 12.5 0.2 6.5 6.6 0.0 3.0 3 0 0 3 3 3 0 Vestigial/Tondu family Mid2 PF04478.12 KNZ81276.1 - 0.0011 18.8 0.6 0.0017 18.2 0.6 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor HA2 PF04408.23 KNZ81277.1 - 6.5e-26 90.7 0.0 6.5e-26 90.7 0.0 2.6 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KNZ81277.1 - 4.8e-20 71.7 0.0 1.5e-19 70.1 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KNZ81277.1 - 2.3e-10 40.8 0.1 1.8e-09 37.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNZ81277.1 - 3.8e-07 30.0 0.0 8.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KNZ81277.1 - 5e-05 23.6 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 KNZ81277.1 - 0.00077 20.0 7.1 0.13 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KNZ81277.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KNZ81277.1 - 0.025 13.8 0.3 0.049 12.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 KNZ81277.1 - 0.027 14.8 0.0 0.09 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 KNZ81277.1 - 0.045 13.7 2.0 0.19 11.7 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ATPase PF06745.13 KNZ81277.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC zf-CCHH PF10283.9 KNZ81278.1 - 0.039 14.0 3.1 0.069 13.1 3.1 1.5 1 0 0 1 1 1 0 PBZ domain zf-AD PF07776.15 KNZ81278.1 - 0.073 13.3 0.0 0.26 11.6 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DASH_Dad1 PF08649.10 KNZ81279.1 - 4.4e-21 74.8 0.7 5.9e-21 74.4 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 KNZ81279.1 - 0.038 14.0 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 NADPH_Ox PF08414.10 KNZ81279.1 - 0.1 12.9 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Pkinase PF00069.25 KNZ81280.1 - 1.2e-61 208.4 0.0 2.9e-61 207.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81280.1 - 4.9e-35 121.1 0.0 7.4e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 KNZ81280.1 - 4e-20 71.4 27.3 2.8e-11 43.1 9.7 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 KNZ81280.1 - 2e-17 63.1 16.6 5.1e-13 48.9 5.2 2.5 2 0 0 2 2 2 2 Hr1 repeat Pkinase_C PF00433.24 KNZ81280.1 - 8.2e-11 42.4 1.8 6.6e-10 39.5 0.4 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 KNZ81280.1 - 9.1e-06 25.9 0.0 1.8e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KNZ81280.1 - 0.14 11.5 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KNZ81280.1 - 0.14 11.0 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain C1_2 PF03107.16 KNZ81280.1 - 0.34 11.2 21.9 0.97 9.8 7.9 2.5 2 0 0 2 2 2 0 C1 domain Endosulfine PF04667.17 KNZ81282.1 - 5.6e-26 90.5 0.1 9.5e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DNA_pol_E_B PF04042.16 KNZ81283.1 - 3.5e-30 105.0 0.2 4.9e-30 104.5 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 KNZ81283.1 - 4.6e-23 82.5 0.5 3.2e-13 50.2 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase alpha subunit B N-terminal SQS_PSY PF00494.19 KNZ81284.1 - 0.0068 15.9 0.6 0.0087 15.6 0.6 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Laps PF10169.9 KNZ81284.1 - 0.01 16.4 2.2 0.01 16.4 2.2 1.9 1 1 1 2 2 2 0 Learning-associated protein HrpB7 PF09486.10 KNZ81284.1 - 0.013 15.9 5.2 0.013 15.9 5.2 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FbpA PF05833.11 KNZ81284.1 - 0.013 14.2 3.7 0.015 14.1 3.7 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF2564 PF10819.8 KNZ81284.1 - 0.02 15.3 2.3 0.042 14.2 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DUF2884 PF11101.8 KNZ81284.1 - 0.024 14.2 5.4 0.03 13.9 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) BLOC1S3 PF15753.5 KNZ81284.1 - 0.033 14.3 0.5 0.044 13.9 0.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4140 PF13600.6 KNZ81284.1 - 0.19 12.2 9.0 0.32 11.4 9.0 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc7 PF08317.11 KNZ81284.1 - 0.27 10.1 10.6 0.019 13.8 5.0 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 KNZ81284.1 - 0.31 9.5 1.8 0.33 9.4 1.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family PEARLI-4 PF05278.12 KNZ81284.1 - 0.36 10.4 11.2 0.018 14.7 4.8 1.8 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4407 PF14362.6 KNZ81284.1 - 0.4 10.0 5.7 0.47 9.7 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 KNZ81284.1 - 0.8 10.3 10.5 0.087 13.4 4.1 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 KNZ81284.1 - 1.4 9.5 17.1 4 8.0 17.1 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 KNZ81284.1 - 1.6 7.8 4.2 1.8 7.5 4.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YscO-like PF16789.5 KNZ81284.1 - 2.2 8.3 14.2 9.3 6.3 14.3 1.8 1 1 0 1 1 1 0 YscO-like protein M PF02370.16 KNZ81284.1 - 7 7.6 9.7 5.4 7.9 3.2 3.0 2 1 1 3 3 2 0 M protein repeat Zn_clus PF00172.18 KNZ81288.1 - 4.6e-07 29.8 11.3 1.2e-06 28.5 11.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CRD PF17979.1 KNZ81289.1 - 1.2e-09 38.4 0.6 1.2e-09 38.4 0.6 2.7 3 0 0 3 3 3 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 KNZ81289.1 - 1.8e-05 24.5 5.5 1.8e-05 24.5 5.5 3.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KNZ81289.1 - 0.00026 20.8 2.8 0.00026 20.8 2.8 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 KNZ81289.1 - 0.0037 17.1 3.2 0.0037 17.1 3.2 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ81289.1 - 0.004 17.4 5.4 0.004 17.4 5.4 4.2 4 1 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 KNZ81289.1 - 0.031 14.2 5.8 0.031 14.2 5.8 3.7 4 0 0 4 4 4 0 zinc-RING finger domain Kelch_4 PF13418.6 KNZ81290.1 - 3.9e-15 55.6 6.9 3.8e-05 23.6 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 KNZ81290.1 - 9.7e-15 54.3 2.1 0.0014 18.8 0.0 4.9 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 KNZ81290.1 - 6.3e-14 51.3 2.3 4.6e-05 22.9 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 KNZ81290.1 - 4.5e-13 49.1 7.5 3.5e-06 27.2 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KNZ81290.1 - 3.7e-11 42.8 0.2 0.0033 17.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 KNZ81290.1 - 4.4e-10 39.1 2.8 0.00086 19.2 0.0 4.6 5 0 0 5 5 5 2 Kelch motif BTB PF00651.31 KNZ81290.1 - 0.12 12.6 0.1 1.2 9.3 0.1 2.3 1 1 0 1 1 1 0 BTB/POZ domain AAA_23 PF13476.6 KNZ81290.1 - 0.16 12.5 13.1 0.26 11.7 13.1 1.2 1 0 0 1 1 1 0 AAA domain FAM199X PF15814.5 KNZ81290.1 - 0.48 9.4 2.8 1.2 8.1 2.8 1.6 1 0 0 1 1 1 0 Protein family FAM199X DDHD PF02862.17 KNZ81290.1 - 2 8.5 8.4 14 5.8 9.7 1.6 2 0 0 2 2 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 KNZ81290.1 - 2.3 8.7 12.0 4.9 7.6 12.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 KNZ81290.1 - 2.4 8.3 11.1 4.3 7.5 11.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1682 PF07946.14 KNZ81290.1 - 3.5 6.7 18.2 5.5 6.1 18.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 KNZ81290.1 - 5.5 6.7 19.7 8.8 6.1 19.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.9 KNZ81290.1 - 6.3 6.3 28.6 0.39 10.3 21.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2052 PF09747.9 KNZ81290.1 - 8 6.5 18.7 14 5.8 18.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Putative_PNPOx PF01243.20 KNZ81291.1 - 2.4e-23 82.1 0.0 6.4e-23 80.8 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 KNZ81291.1 - 2.1e-19 69.3 2.2 5e-19 68.1 2.2 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 KNZ81291.1 - 1.5e-05 25.5 0.0 2.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 KNZ81291.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Glycolytic PF00274.19 KNZ81292.1 - 1.7e-67 227.6 0.0 2.7e-41 141.4 0.0 2.1 1 1 1 2 2 2 2 Fructose-bisphosphate aldolase class-I DUF1996 PF09362.10 KNZ81293.1 - 2.3e-76 256.9 2.0 2.8e-76 256.6 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_cc PF11790.8 KNZ81294.1 - 7e-53 179.7 0.3 7.9e-53 179.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core zf-CCHC PF00098.23 KNZ81296.1 - 0.24 11.5 1.2 0.42 10.8 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ81296.1 - 0.32 10.8 2.2 0.52 10.1 2.2 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger RasGEF PF00617.19 KNZ81297.1 - 1.1e-53 182.1 1.2 1.1e-53 182.1 1.2 2.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 KNZ81297.1 - 5.3e-20 71.6 1.6 1.7e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 KNZ81297.1 - 1e-14 53.9 0.4 3e-14 52.4 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KNZ81297.1 - 2e-13 49.8 0.0 5.1e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KNZ81297.1 - 1.2e-11 44.3 0.6 4.7e-11 42.4 0.3 2.2 2 0 0 2 2 2 1 Variant SH3 domain RasGEF PF00617.19 KNZ81298.1 - 2.9e-57 193.7 0.7 6.1e-57 192.7 0.7 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KNZ81298.1 - 4.7e-18 65.4 2.2 6.4e-18 64.9 0.1 2.4 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 KNZ81298.1 - 5.7e-16 57.8 0.1 1.2e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KNZ81298.1 - 2.6e-13 49.6 0.2 6.5e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ81298.1 - 2.1e-12 46.5 0.0 3.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain THOC7 PF05615.13 KNZ81298.1 - 0.069 13.4 1.9 19 5.5 0.0 3.6 3 0 0 3 3 3 0 Tho complex subunit 7 GTP_EFTU PF00009.27 KNZ81299.1 - 3.3e-57 193.2 0.0 7e-57 192.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KNZ81299.1 - 6.3e-16 58.2 0.0 2e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 KNZ81299.1 - 3.8e-09 36.5 0.0 1.1e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KNZ81299.1 - 3.2e-07 30.6 0.0 8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ81299.1 - 0.00025 21.1 0.0 0.00059 19.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 KNZ81299.1 - 0.031 14.1 0.0 0.28 11.0 0.0 2.7 2 1 0 2 2 2 0 Elongation factor G, domain IV Afaf PF15339.6 KNZ81299.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Acrosome formation-associated factor Septin PF00735.18 KNZ81299.1 - 0.11 11.8 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 KNZ81299.1 - 0.12 11.8 0.2 0.61 9.5 0.2 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit CwfJ_C_2 PF04676.14 KNZ81300.1 - 9.8e-36 122.6 0.9 3.8e-34 117.5 0.0 2.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KNZ81300.1 - 1.3e-31 109.0 0.0 1.9e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 p450 PF00067.22 KNZ81301.1 - 3.1e-63 214.1 0.0 4e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HpcH_HpaI PF03328.14 KNZ81302.1 - 1.4e-39 135.5 0.0 2.2e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 KNZ81302.1 - 1.1e-11 44.5 0.0 2.9e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold HA2 PF04408.23 KNZ81303.1 - 8.8e-22 77.4 0.0 8.8e-22 77.4 0.0 3.4 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KNZ81303.1 - 5.9e-20 71.4 0.6 1.4e-19 70.3 0.6 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KNZ81303.1 - 4.3e-15 56.0 0.0 1.2e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KNZ81303.1 - 1.5e-07 31.3 0.1 1e-06 28.6 0.0 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KNZ81303.1 - 4.5e-05 23.3 0.1 0.00014 21.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KNZ81303.1 - 4.8e-05 23.7 0.0 0.00022 21.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ81303.1 - 0.0016 18.8 2.9 0.0018 18.7 0.1 2.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 KNZ81303.1 - 0.0076 15.3 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KNZ81303.1 - 0.12 12.3 4.5 0.59 10.1 0.1 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Herpes_ori_bp PF02399.15 KNZ81303.1 - 0.15 10.1 0.0 0.23 9.5 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein adh_short PF00106.25 KNZ81304.1 - 1.6e-27 96.3 0.0 2.3e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ81304.1 - 6.4e-23 81.5 0.0 3.6e-22 79.1 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ81304.1 - 8.4e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KNZ81304.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KNZ81304.1 - 0.0016 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 KNZ81304.1 - 0.094 12.5 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LIM_bind PF01803.16 KNZ81306.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 LIM-domain binding protein CoA_transf_3 PF02515.17 KNZ81307.1 - 1.5e-125 419.2 0.0 1.7e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III CoA_transf_3 PF02515.17 KNZ81310.1 - 3.7e-129 431.0 0.0 4.2e-129 430.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Helicase_C_2 PF13307.6 KNZ81311.1 - 9e-55 185.5 0.0 5e-54 183.0 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 KNZ81311.1 - 1e-42 145.7 0.1 2.3e-41 141.4 0.0 2.6 2 1 0 2 2 2 1 DEAD_2 PhoH PF02562.16 KNZ81311.1 - 5.3e-05 22.8 0.1 0.063 12.7 0.0 2.7 3 0 0 3 3 3 2 PhoH-like protein ResIII PF04851.15 KNZ81311.1 - 0.00015 21.8 0.0 0.023 14.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KNZ81311.1 - 0.002 17.9 0.6 0.015 15.1 0.1 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KNZ81311.1 - 0.0048 17.2 0.1 5.2 7.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KNZ81311.1 - 0.032 13.3 0.1 0.093 11.8 0.1 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 KNZ81311.1 - 0.049 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KNZ81311.1 - 0.11 12.2 0.0 0.6 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF563 PF04577.14 KNZ81312.1 - 6.3e-06 26.5 0.1 1.4e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF563) zf-CCHC_3 PF13917.6 KNZ81314.1 - 2.1e-15 56.4 0.4 2.1e-15 56.4 0.4 1.9 2 0 0 2 2 2 1 Zinc knuckle ATP-synt_C PF00137.21 KNZ81315.1 - 3.9e-29 100.8 36.9 5e-20 71.6 11.9 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Ferric_reduct PF01794.19 KNZ81315.1 - 1.5 8.9 5.8 0.56 10.3 0.5 2.3 1 1 0 2 2 2 0 Ferric reductase like transmembrane component Peptidase_M20 PF01546.28 KNZ81316.1 - 1.6e-27 96.6 0.0 2.7e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 KNZ81316.1 - 1.8e-14 53.9 15.8 0.00012 22.8 0.1 7.6 7 0 0 7 7 7 3 WD domain, G-beta repeat M20_dimer PF07687.14 KNZ81316.1 - 2.9e-11 43.2 0.0 5.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 KNZ81316.1 - 0.0094 16.2 0.1 6 7.2 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 KNZ81316.1 - 0.06 13.3 2.0 0.11 12.5 0.0 2.5 3 0 0 3 3 3 0 PQQ enzyme repeat Spt5-NGN PF03439.13 KNZ81318.1 - 9.1e-22 76.8 0.0 2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 KNZ81318.1 - 3.7e-18 64.8 22.9 0.00076 19.3 0.1 7.2 7 0 0 7 7 7 4 KOW motif Spt5_N PF11942.8 KNZ81318.1 - 3.1e-14 53.7 11.8 3.1e-14 53.7 11.8 2.6 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KNZ81318.1 - 1.9e-10 41.2 13.1 1.9e-10 41.2 13.1 4.0 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 S1_2 PF13509.6 KNZ81318.1 - 0.086 12.9 1.1 0.92 9.6 0.1 3.1 4 0 0 4 4 4 0 S1 domain YajC PF02699.15 KNZ81318.1 - 1.3 9.0 6.3 2 8.4 1.0 3.0 2 1 1 3 3 3 0 Preprotein translocase subunit ProQ_C PF17516.2 KNZ81318.1 - 1.9 8.0 6.7 16 5.0 0.4 3.8 3 0 0 3 3 3 0 ProQ C-terminal domain LAP1C PF05609.12 KNZ81318.1 - 5.4 6.0 14.4 9.2 5.2 14.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) F-box-like PF12937.7 KNZ81319.1 - 9.1e-06 25.5 2.2 1.1e-05 25.2 0.2 2.3 2 0 0 2 2 2 1 F-box-like DJ-1_PfpI PF01965.24 KNZ81320.1 - 3.1e-34 118.2 0.0 3.6e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Repressor_Mnt PF11423.8 KNZ81320.1 - 0.00039 20.1 0.7 0.095 12.5 0.0 3.1 3 0 0 3 3 3 1 Regulatory protein Mnt ThiJ_like PF17124.5 KNZ81320.1 - 0.00044 20.0 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase_3 PF07685.14 KNZ81320.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ATXN-1_C PF12547.8 KNZ81320.1 - 0.15 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator BTB PF00651.31 KNZ81321.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain RL PF17797.1 KNZ81322.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.6 1 1 0 1 1 1 0 RL domain zf-RVT PF13966.6 KNZ81323.1 - 0.00075 20.2 3.7 0.0026 18.4 2.0 2.1 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase DUF987 PF06174.11 KNZ81324.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF987) RVT_1 PF00078.27 KNZ81325.1 - 0.0092 15.5 0.0 0.0092 15.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YMF19 PF02326.15 KNZ81326.1 - 0.42 11.4 0.1 0.42 11.4 0.1 2.9 3 0 0 3 3 3 0 Plant ATP synthase F0 Pro_isomerase PF00160.21 KNZ81327.1 - 4.1e-43 147.4 0.0 6.4e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KNZ81327.1 - 3e-07 30.0 3.2 0.03 14.4 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ81327.1 - 5.2e-06 26.1 3.1 0.071 13.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 KNZ81327.1 - 0.046 13.8 2.8 0.31 11.1 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 KNZ81327.1 - 0.047 13.4 0.2 0.047 13.4 0.2 2.6 3 0 0 3 3 3 0 TPR repeat DUF4145 PF13643.6 KNZ81327.1 - 0.12 12.5 0.3 19 5.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) RhoGAP PF00620.27 KNZ81328.1 - 0.0026 17.6 0.0 0.24 11.2 0.0 2.4 1 1 1 2 2 2 2 RhoGAP domain Reo_sigmaC_M PF17750.1 KNZ81328.1 - 0.027 14.3 0.2 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein triple beta spiral DUF3868 PF12984.7 KNZ81328.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) Motile_Sperm PF00635.26 KNZ81328.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 MSP (Major sperm protein) domain Retrotran_gag_2 PF14223.6 KNZ81329.1 - 0.015 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type HABP4_PAI-RBP1 PF04774.15 KNZ81330.1 - 0.00068 20.5 2.8 0.001 19.9 2.8 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RVT_1 PF00078.27 KNZ81330.1 - 0.011 15.3 0.1 0.018 14.5 0.0 1.4 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TMCO5 PF14992.6 KNZ81330.1 - 0.066 12.8 1.6 0.082 12.5 1.6 1.1 1 0 0 1 1 1 0 TMCO5 family MFS_1 PF07690.16 KNZ81331.1 - 1.1e-40 139.7 42.5 1.1e-40 139.7 42.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KNZ81331.1 - 4.7e-08 31.9 1.4 4.7e-08 31.9 1.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KNZ81331.1 - 0.0017 17.3 41.8 0.052 12.4 41.8 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter AMP-binding PF00501.28 KNZ81332.1 - 1.7e-28 99.4 0.0 3.8e-27 94.9 0.0 2.4 3 0 0 3 3 3 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KNZ81332.1 - 1.9e-24 86.3 0.0 2.9e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KNZ81332.1 - 5.7e-09 35.8 0.0 8.9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KNZ81332.1 - 0.00064 19.7 0.0 0.0063 16.4 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KNZ81332.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 KNZ81333.1 - 1.3e-16 60.5 55.2 1.9e-11 43.5 32.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily BatA PF07584.11 KNZ81333.1 - 0.0097 16.3 1.0 0.7 10.3 0.0 2.6 2 0 0 2 2 2 2 Aerotolerance regulator N-terminal RNA_POL_M_15KD PF02150.16 KNZ81334.1 - 3.2e-08 33.3 3.6 3.2e-08 33.3 3.6 2.7 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 KNZ81334.1 - 1.4e-07 31.3 6.6 7.4e-06 25.7 2.0 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) zf-C2H2 PF00096.26 KNZ81334.1 - 0.25 11.9 5.0 0.25 11.9 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type C1_4 PF07975.12 KNZ81334.1 - 0.51 10.6 7.9 0.95 9.8 1.0 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain DUF2197 PF09963.9 KNZ81334.1 - 0.73 10.1 6.2 5.7 7.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) zf-C2H2_4 PF13894.6 KNZ81334.1 - 3.3 8.8 5.8 2.6 9.1 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Hydrophobin PF01185.18 KNZ81335.1 - 3.3e-17 62.9 12.0 4.3e-17 62.5 12.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MF_alpha_N PF05436.11 KNZ81335.1 - 0.022 14.6 0.4 0.098 12.6 0.0 2.0 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus Ribosomal_L27e PF01777.18 KNZ81336.1 - 1.1e-35 121.8 1.6 1.6e-35 121.3 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KNZ81336.1 - 0.0055 16.6 1.2 0.016 15.1 1.2 1.9 1 0 0 1 1 1 1 KOW motif Mito_carr PF00153.27 KNZ81337.1 - 1.5e-14 53.7 0.0 5.5e-08 32.6 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein F-box-like PF12937.7 KNZ81338.1 - 0.26 11.2 5.9 10 6.1 4.8 3.1 2 1 0 2 2 2 0 F-box-like Vps39_2 PF10367.9 KNZ81339.1 - 1.7e-07 31.6 0.0 7.7e-07 29.5 0.0 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 KNZ81339.1 - 2e-07 31.2 0.1 2e-07 31.2 0.1 2.6 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 KNZ81339.1 - 0.0001 22.2 0.1 0.00059 19.7 0.1 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Ank_4 PF13637.6 KNZ81340.1 - 3.1e-17 62.7 0.0 1.3e-06 28.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ81340.1 - 4.3e-16 58.8 0.1 3.6e-06 27.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ81340.1 - 5.5e-15 55.7 0.0 1.3e-09 38.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ81340.1 - 5.5e-10 38.6 0.0 0.41 11.3 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 KNZ81340.1 - 1.3e-07 31.7 0.0 2.5 8.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat NT-C2 PF10358.9 KNZ81341.1 - 2.8e-19 69.3 0.0 2.6e-18 66.1 0.0 2.1 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Myb_Cef PF11831.8 KNZ81343.1 - 1.2e-56 191.9 0.1 1.2e-56 191.9 0.1 3.1 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KNZ81343.1 - 8.5e-21 73.9 9.2 9.1e-11 41.8 1.3 3.8 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KNZ81343.1 - 2.8e-17 62.7 6.5 3.1e-12 46.6 2.8 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain DUF1690 PF07956.11 KNZ81344.1 - 1.4e-32 113.0 2.2 1.9e-32 112.6 2.2 1.1 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Allexi_40kDa PF05549.11 KNZ81345.1 - 0.055 13.0 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Sel1 PF08238.12 KNZ81346.1 - 3e-48 161.1 19.1 4.5e-10 39.9 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat PITH PF06201.13 KNZ81346.1 - 8.8e-37 126.6 0.4 1.4e-36 126.0 0.4 1.3 1 0 0 1 1 1 1 PITH domain JHD PF17811.1 KNZ81346.1 - 4.6e-10 40.0 0.0 1.4e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 KNZ81346.1 - 2.3e-08 34.5 1.0 2.2e-07 31.3 1.0 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 KNZ81346.1 - 0.00016 21.5 7.2 0.00028 20.7 7.2 1.4 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 KNZ81346.1 - 0.0079 15.9 0.4 0.032 14.0 0.4 1.9 1 1 0 1 1 1 1 Cupin-like domain TPR_14 PF13428.6 KNZ81346.1 - 0.015 16.0 4.6 7.1 7.7 0.7 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat PHD_2 PF13831.6 KNZ81346.1 - 0.32 10.6 10.5 0.066 12.8 6.7 1.8 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 KNZ81346.1 - 0.79 9.7 2.5 1.8 8.5 2.5 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-CW PF07496.15 KNZ81346.1 - 2.3 8.3 6.0 5.6 7.1 6.0 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger Retrotran_gag_2 PF14223.6 KNZ81347.1 - 1.1e-07 31.6 1.3 1.3e-07 31.4 1.3 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FBA_1 PF07734.13 KNZ81347.1 - 0.056 13.4 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 F-box associated NAPRTase_N PF17767.1 KNZ81347.1 - 0.083 13.3 0.1 0.13 12.7 0.1 1.3 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain GNAT_acetyltran PF12746.7 KNZ81347.1 - 0.14 11.7 0.2 0.16 11.5 0.2 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Integrase_H2C2 PF17921.1 KNZ81349.1 - 1e-07 31.9 1.1 1e-07 31.9 1.1 2.3 3 0 0 3 3 3 1 Integrase zinc binding domain zf-RING_2 PF13639.6 KNZ81349.1 - 1.7 9.0 0.0 1.7 9.0 0.0 2.7 4 0 0 4 4 4 0 Ring finger domain CPSase_L_D2 PF02786.17 KNZ81351.1 - 3.1e-05 23.6 0.2 5e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D2 PF02786.17 KNZ81354.1 - 7.3e-07 28.9 0.1 8.3e-07 28.7 0.1 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain MTES_1575 PF18741.1 KNZ81354.1 - 0.05 13.8 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 REase_MTES_1575 zf-CCHC PF00098.23 KNZ81355.1 - 0.0081 16.2 5.4 0.017 15.2 5.4 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 KNZ81355.1 - 0.11 12.5 1.5 0.24 11.4 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle PhoQ_Sensor PF08918.10 KNZ81356.1 - 0.16 11.9 1.0 0.34 10.7 1.0 1.5 1 0 0 1 1 1 0 PhoQ Sensor UbiA PF01040.18 KNZ81357.1 - 3e-34 118.5 7.8 4.1e-34 118.0 7.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Toxin_37 PF11415.8 KNZ81357.1 - 0.034 14.0 0.5 0.32 10.9 0.5 2.5 2 0 0 2 2 2 0 Antifungal peptide termicin Dala_Dala_lig_N PF01820.21 KNZ81357.1 - 0.22 12.0 0.0 0.4 11.2 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Cep57_CLD_2 PF14197.6 KNZ81358.1 - 0.052 13.7 0.2 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Not3 PF04065.15 KNZ81359.1 - 0.015 14.8 7.6 0.11 11.9 0.2 3.1 3 0 0 3 3 3 0 Not1 N-terminal domain, CCR4-Not complex component Spidroin_N PF16763.5 KNZ81359.1 - 0.062 13.3 1.5 0.33 11.0 0.2 2.8 1 1 2 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term SUIM_assoc PF16619.5 KNZ81359.1 - 0.072 13.2 1.2 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Baculo_PEP_C PF04513.12 KNZ81359.1 - 0.13 12.4 1.3 0.27 11.3 0.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AKAP95 PF04988.12 KNZ81359.1 - 0.21 11.8 3.0 0.83 9.9 0.2 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) CCDC53 PF10152.9 KNZ81359.1 - 6.5 7.2 7.7 0.8 10.1 0.2 2.4 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Abhydrolase_1 PF00561.20 KNZ81360.1 - 4.7e-08 33.0 0.0 8.6e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ81360.1 - 2.6e-06 26.9 0.0 1.1e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KNZ81360.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 KNZ81360.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family APH PF01636.23 KNZ81361.1 - 3.7e-10 40.1 0.3 1.4e-09 38.2 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KNZ81361.1 - 6.2e-05 22.7 0.0 9.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KNZ81361.1 - 0.019 14.3 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain RIO1 PF01163.22 KNZ81361.1 - 0.096 12.3 0.0 0.75 9.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KNZ81361.1 - 0.32 10.3 0.4 7.5 5.8 0.1 2.0 1 1 1 2 2 2 0 Ecdysteroid kinase Helitron_like_N PF14214.6 KNZ81362.1 - 3.8e-24 86.0 0.0 5.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus BAH PF01426.18 KNZ81362.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 BAH domain PIF1 PF05970.14 KNZ81363.1 - 9.9e-07 28.2 0.1 1.7e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 PIF1-like helicase ResIII PF04851.15 KNZ81363.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ81363.1 - 0.076 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Herpes_Helicase PF02689.14 KNZ81364.1 - 1.1e-06 26.9 0.0 1.2e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ81364.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain Neur PF00064.18 KNZ81368.1 - 0.076 11.8 0.3 0.11 11.2 0.3 1.2 1 0 0 1 1 1 0 Neuraminidase Sm_like PF16243.5 KNZ81368.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Sm_like domain Chromo PF00385.24 KNZ81369.1 - 1.9e-17 62.9 0.1 2.3e-17 62.6 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 KNZ81369.1 - 0.0066 16.3 1.2 0.0082 16.0 1.2 1.2 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 KNZ81369.1 - 0.036 14.2 0.1 0.049 13.8 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Chromo PF00385.24 KNZ81371.1 - 1.2e-08 34.7 0.1 1.4e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SWIRM-assoc_2 PF16496.5 KNZ81371.1 - 0.0073 15.2 0.1 0.0076 15.2 0.1 1.1 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal Tudor-knot PF11717.8 KNZ81371.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF2499 PF10693.9 KNZ81373.1 - 0.052 13.8 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) Mt_ATP-synt_B PF05405.14 KNZ81374.1 - 5.4e-42 143.2 11.4 6.3e-42 143.0 11.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF5623 PF18536.1 KNZ81374.1 - 0.01 16.1 1.1 0.031 14.5 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5623) MMM1 PF10296.9 KNZ81374.1 - 0.033 13.2 2.2 0.038 13.1 2.2 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 DUF2526 PF10735.9 KNZ81374.1 - 0.44 10.7 3.3 1.3 9.3 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) Glyco_hydro_61 PF03443.14 KNZ81375.1 - 8e-42 143.5 0.0 8.9e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F-box-like PF12937.7 KNZ81377.1 - 3.5e-06 26.8 0.1 1.6e-05 24.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like Peroxin-3 PF04882.12 KNZ81378.1 - 8.5e-115 384.4 4.4 1.5e-114 383.6 4.4 1.4 1 1 0 1 1 1 1 Peroxin-3 SPATA24 PF15175.6 KNZ81378.1 - 0.0023 17.9 0.7 0.0049 16.8 0.7 1.4 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 Atg14 PF10186.9 KNZ81378.1 - 0.084 11.9 3.0 0.16 11.0 3.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lzipper-MIP1 PF14389.6 KNZ81378.1 - 0.88 9.9 6.6 30 5.0 0.4 3.8 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Retrotran_gag_2 PF14223.6 KNZ81382.1 - 2.8e-16 59.4 0.1 4e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF2235 PF09994.9 KNZ81384.1 - 0.037 13.4 0.2 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4820 PF16091.5 KNZ81385.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Glyoxalase_4 PF13669.6 KNZ81386.1 - 0.14 12.5 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TERB2 PF15101.6 KNZ81388.1 - 6.1e-05 23.2 0.0 0.00012 22.2 0.0 1.5 1 1 0 1 1 1 1 Telomere-associated protein TERB2 Retrotran_gag_2 PF14223.6 KNZ81391.1 - 4.1e-16 58.9 0.7 6.5e-16 58.3 0.7 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ81391.1 - 0.015 15.0 0.2 0.031 14.0 0.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger DUF1054 PF06335.12 KNZ81391.1 - 0.062 13.2 5.3 0.3 11.0 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) ZapA PF05164.13 KNZ81391.1 - 0.11 13.0 2.9 0.4 11.2 2.9 2.1 1 1 0 1 1 1 0 Cell division protein ZapA Herpes_V23 PF01802.17 KNZ81391.1 - 0.11 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Coilin_N PF15862.5 KNZ81391.1 - 0.89 9.4 6.6 1.5 8.6 6.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus Aldedh PF00171.22 KNZ81393.1 - 4.8e-119 397.9 0.0 6.1e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KNZ81393.1 - 2.9e-06 26.6 0.0 1e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Cellulase PF00150.18 KNZ81394.1 - 5.8e-14 52.2 6.0 1.2e-13 51.1 5.8 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 KNZ81394.1 - 0.0016 17.9 1.0 0.3 10.4 1.0 2.4 1 1 0 1 1 1 1 Beta-galactosidase JSRP PF15312.6 KNZ81394.1 - 0.04 13.8 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Mito_carr PF00153.27 KNZ81395.1 - 3.7e-53 177.4 0.1 1.4e-17 63.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Proteasome PF00227.26 KNZ81396.1 - 2.8e-48 163.9 0.1 3.4e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KNZ81396.1 - 2.6e-09 36.3 0.1 2.6e-09 36.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal PRKG1_interact PF15898.5 KNZ81397.1 - 5.4e-06 27.3 83.7 0.26 12.2 8.8 6.4 6 1 0 6 6 6 5 cGMP-dependent protein kinase interacting domain PKcGMP_CC PF16808.5 KNZ81397.1 - 0.0095 15.8 20.1 16 5.5 0.2 6.2 5 0 0 5 5 5 3 Coiled-coil N-terminus of cGMP-dependent protein kinase AAA_13 PF13166.6 KNZ81397.1 - 0.028 13.1 80.1 0.008 14.9 27.1 3.5 1 1 2 3 3 3 0 AAA domain LysM PF01476.20 KNZ81397.1 - 0.081 13.0 19.3 14 5.8 0.1 5.5 5 0 0 5 5 5 0 LysM domain Syntaxin PF00804.25 KNZ81397.1 - 0.17 11.5 86.1 0.62 9.7 10.9 5.6 2 2 3 5 5 5 0 Syntaxin FAD-SLDH PF12318.8 KNZ81397.1 - 0.76 9.8 32.7 3.2 7.8 0.9 5.6 5 0 0 5 5 5 0 Membrane bound FAD containing D-sorbitol dehydrogenase RPW8 PF05659.11 KNZ81397.1 - 4.5 7.0 36.5 0.11 12.2 0.8 5.3 5 0 0 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RRF PF01765.19 KNZ81398.1 - 4.9e-28 98.1 0.6 6e-28 97.8 0.6 1.1 1 0 0 1 1 1 1 Ribosome recycling factor MatE PF01554.18 KNZ81399.1 - 6.4e-53 178.7 31.1 1.6e-27 96.2 12.7 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KNZ81399.1 - 3e-06 27.3 13.2 3e-06 27.3 13.2 3.8 2 2 3 5 5 5 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 KNZ81400.1 - 9.6e-57 191.1 27.8 1.3e-28 99.7 9.4 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KNZ81400.1 - 5.7e-09 36.2 10.1 5.7e-09 36.2 10.1 3.8 2 2 2 4 4 4 2 Polysaccharide biosynthesis C-terminal domain GST_N_3 PF13417.6 KNZ81401.1 - 5.1e-08 33.2 0.0 1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KNZ81401.1 - 4.6e-06 26.9 0.0 1.1e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KNZ81401.1 - 0.00016 21.9 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KNZ81401.1 - 0.0004 20.3 0.0 0.00076 19.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KNZ81401.1 - 0.023 15.3 0.1 0.046 14.3 0.1 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alpha-L-AF_C PF06964.12 KNZ81402.1 - 3.9e-37 127.9 0.1 2.2e-36 125.5 0.1 2.0 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 KNZ81402.1 - 0.13 12.6 3.9 0.19 12.0 0.2 2.9 3 0 0 3 3 3 0 Carbohydrate binding domain Metallophos PF00149.28 KNZ81403.1 - 8.7e-11 42.7 0.1 1.1e-10 42.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ81403.1 - 2.1e-06 28.0 0.0 6.1e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_16 PF00722.21 KNZ81404.1 - 8.2e-05 22.1 0.0 0.0002 20.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4232 PF14016.6 KNZ81404.1 - 0.031 14.4 0.2 0.064 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) RNase_H PF00075.24 KNZ81408.1 - 3.7e-18 66.1 0.1 7.9e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 RNase H Methyltransf_16 PF10294.9 KNZ81410.1 - 5.1e-05 23.1 0.0 0.062 13.0 0.0 2.5 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 KNZ81410.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain S1-P1_nuclease PF02265.16 KNZ81411.1 - 7e-45 153.8 0.0 1.8e-43 149.2 0.0 2.4 1 1 0 1 1 1 1 S1/P1 Nuclease MFS_1 PF07690.16 KNZ81414.1 - 7e-24 84.4 32.7 1.2e-23 83.7 32.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KNZ81414.1 - 0.0064 15.0 5.9 0.0097 14.4 5.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) YdjM PF04307.14 KNZ81414.1 - 2.1 7.6 8.8 1.1 8.5 2.9 3.4 2 1 1 3 3 3 0 LexA-binding, inner membrane-associated putative hydrolase MFS_1 PF07690.16 KNZ81415.1 - 5.5e-19 68.3 26.0 8.3e-19 67.7 26.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldedh PF00171.22 KNZ81416.1 - 1.1e-107 360.4 0.4 1.7e-107 359.9 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KNZ81416.1 - 0.0028 16.8 0.1 0.011 14.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Sin3a_C PF16879.5 KNZ81417.1 - 3.2e-80 269.9 1.2 5.2e-79 265.9 0.0 3.2 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 KNZ81417.1 - 5.3e-38 129.0 0.4 2.2e-37 127.0 0.2 2.2 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 KNZ81417.1 - 1.2e-33 114.9 8.1 1.9e-16 59.9 0.0 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat DDE_3 PF13358.6 KNZ81417.1 - 0.13 12.0 3.2 17 5.2 0.5 3.6 2 1 1 3 3 3 0 DDE superfamily endonuclease DUF3915 PF13054.6 KNZ81417.1 - 0.23 11.4 3.0 0.72 9.8 3.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 KNZ81417.1 - 9.6 4.3 18.7 0.023 13.0 8.8 1.5 2 0 0 2 2 2 0 Atrophin-1 family Pkinase PF00069.25 KNZ81418.1 - 9.4e-08 31.7 0.0 3.1e-07 30.0 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81418.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 KNZ81419.1 - 4.3e-08 32.8 0.0 1.6e-07 31.0 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81419.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase FmiP_Thoc5 PF09766.9 KNZ81420.1 - 0.2 10.9 5.8 0.057 12.7 2.9 1.5 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 PCNA_N PF00705.18 KNZ81421.1 - 9.6e-53 177.3 3.1 9.6e-53 177.3 3.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KNZ81421.1 - 5.2e-40 136.6 0.0 1.6e-18 67.1 0.0 2.8 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KNZ81421.1 - 5.6e-05 22.7 0.0 0.00032 20.2 0.0 2.1 2 1 0 2 2 2 1 Rad9 Hus1 PF04005.12 KNZ81421.1 - 0.14 11.2 4.9 8.6 5.4 4.9 3.3 1 1 0 1 1 1 0 Hus1-like protein CDC45 PF02724.14 KNZ81421.1 - 0.22 9.8 21.0 0.36 9.1 21.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 KNZ81421.1 - 1.1 7.4 31.9 1.7 6.8 31.9 1.2 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 KNZ81421.1 - 3.6 6.6 17.6 5 6.1 17.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DAO PF01266.24 KNZ81422.1 - 6.3e-41 141.1 0.3 7.3e-41 140.9 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ81422.1 - 3e-06 26.7 0.1 0.0032 16.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KNZ81422.1 - 4.8e-06 26.7 0.1 1.5e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KNZ81422.1 - 5.3e-05 22.7 0.0 0.067 12.5 0.0 2.4 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KNZ81422.1 - 0.0012 18.2 0.0 0.08 12.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ81422.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KNZ81422.1 - 0.0023 18.0 0.1 0.0096 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KNZ81422.1 - 0.012 16.2 0.9 0.64 10.6 0.1 3.3 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase AP_endonuc_2 PF01261.24 KNZ81422.1 - 0.053 13.0 0.1 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF371 PF04027.13 KNZ81422.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF371) MCRA PF06100.11 KNZ81422.1 - 0.089 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 MCRA family Pkinase PF00069.25 KNZ81423.1 - 5.2e-09 35.9 0.0 1.5e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81423.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase AAA PF00004.29 KNZ81427.1 - 1.2e-60 203.7 0.0 1.9e-45 154.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KNZ81427.1 - 8e-10 38.4 0.9 5.2e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 KNZ81427.1 - 4.6e-07 30.4 0.1 0.006 17.0 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 KNZ81427.1 - 7.1e-07 29.1 0.0 0.0038 17.0 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KNZ81427.1 - 8.6e-05 22.6 0.1 0.02 14.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KNZ81427.1 - 0.00044 20.8 0.0 0.027 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 KNZ81427.1 - 0.00048 19.5 0.0 0.029 13.6 0.0 2.8 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_22 PF13401.6 KNZ81427.1 - 0.00064 20.0 0.5 0.028 14.7 0.1 3.1 2 1 1 3 3 3 1 AAA domain Vps4_C PF09336.10 KNZ81427.1 - 0.00091 19.2 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 KNZ81427.1 - 0.0022 17.7 0.0 0.0092 15.7 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein ATPase PF06745.13 KNZ81427.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.26 KNZ81427.1 - 0.0029 17.3 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 KNZ81427.1 - 0.0034 17.0 1.1 0.015 14.9 0.1 2.4 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KNZ81427.1 - 0.004 17.3 0.0 0.33 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KNZ81427.1 - 0.004 17.5 0.0 0.08 13.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 KNZ81427.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 KNZ81427.1 - 0.0059 16.7 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 KNZ81427.1 - 0.0071 16.3 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 KNZ81427.1 - 0.0076 15.4 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 KNZ81427.1 - 0.011 15.2 0.1 0.043 13.2 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KNZ81427.1 - 0.02 14.4 0.0 0.087 12.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 KNZ81427.1 - 0.054 13.4 0.0 0.58 10.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 KNZ81427.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.13 KNZ81427.1 - 0.065 12.4 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KNZ81427.1 - 0.069 12.9 0.1 0.18 11.5 0.1 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 KNZ81427.1 - 0.082 12.8 0.2 3.1 7.7 0.1 2.8 3 0 0 3 3 2 0 NACHT domain Cytidylate_kin PF02224.18 KNZ81427.1 - 0.083 12.6 0.1 17 5.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 KNZ81427.1 - 0.093 13.0 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Gar1 PF04410.14 KNZ81428.1 - 1.1e-36 126.0 0.0 1.4e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Mis14 PF08641.12 KNZ81429.1 - 1.8e-07 31.5 0.2 3.7e-07 30.5 0.1 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like DUF572 PF04502.13 KNZ81430.1 - 1e-65 222.6 6.4 1.2e-65 222.3 6.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 KNZ81430.1 - 0.01 15.7 0.9 0.54 10.3 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FAM176 PF14851.6 KNZ81430.1 - 2.7 7.7 10.2 7.5 6.2 10.2 1.7 1 1 0 1 1 1 0 FAM176 family HA2 PF04408.23 KNZ81431.1 - 1.1e-16 61.1 0.0 2.3e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KNZ81431.1 - 4.6e-16 59.1 0.0 1e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KNZ81431.1 - 2.8e-09 37.2 0.0 5.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KNZ81431.1 - 2.8e-06 27.2 0.0 7.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KNZ81431.1 - 5.8e-06 26.6 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KNZ81431.1 - 0.00055 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KNZ81431.1 - 0.0065 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KNZ81431.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KNZ81431.1 - 0.024 14.3 0.0 0.22 11.1 0.1 2.4 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 KNZ81431.1 - 0.071 13.1 0.1 1.5 8.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 KNZ81431.1 - 0.21 10.8 0.4 0.93 8.7 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin gag-asp_proteas PF13975.6 KNZ81433.1 - 0.018 15.6 0.0 0.057 14.0 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease rve PF00665.26 KNZ81433.1 - 0.022 15.0 0.0 0.058 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Asp_protease_2 PF13650.6 KNZ81433.1 - 0.036 14.7 0.0 0.087 13.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC PF00098.23 KNZ81433.1 - 0.25 11.5 1.4 0.62 10.2 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 KNZ81433.1 - 0.27 11.0 2.7 0.65 9.8 2.7 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger gag-asp_proteas PF13975.6 KNZ81435.1 - 8.9e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81435.1 - 0.0013 19.3 0.0 0.003 18.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease DUF659 PF04937.15 KNZ81436.1 - 0.056 13.3 0.1 0.092 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) Myosin_head PF00063.21 KNZ81439.1 - 2e-260 865.7 3.1 1.1e-259 863.4 0.0 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 KNZ81439.1 - 7.1e-26 90.5 1.8 7.1e-26 90.5 1.8 3.7 4 0 0 4 4 4 1 DIL domain IQ PF00612.27 KNZ81439.1 - 7.4e-09 34.6 33.7 0.034 13.9 1.8 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 KNZ81439.1 - 0.017 14.9 0.2 0.045 13.6 0.2 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KNZ81439.1 - 0.055 13.7 3.8 0.063 13.5 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 KNZ81439.1 - 0.51 10.7 0.0 0.51 10.7 0.0 4.0 3 1 0 3 3 3 0 AAA ATPase domain T6PP_N PF18572.1 KNZ81439.1 - 7.6 6.4 9.4 1.4 8.8 3.3 2.9 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain zf-AN1 PF01428.16 KNZ81440.1 - 1.1e-07 31.9 3.8 1.6e-07 31.4 3.8 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger S1_2 PF13509.6 KNZ81440.1 - 0.13 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 S1 domain Snf7 PF03357.21 KNZ81441.1 - 1.7e-39 135.2 23.5 3.9e-39 134.0 22.8 1.7 2 0 0 2 2 2 1 Snf7 HCMV_UL139 PF12507.8 KNZ81441.1 - 0.045 14.1 1.6 0.099 13.0 1.6 1.6 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF1002 PF06207.11 KNZ81441.1 - 0.29 10.6 6.9 0.054 13.0 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) DUF3682 PF12446.8 KNZ81441.1 - 0.33 11.4 3.8 0.24 11.9 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) DUF4407 PF14362.6 KNZ81441.1 - 0.68 9.2 11.7 5.4 6.3 7.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) CHDCT2 PF08074.11 KNZ81441.1 - 1.6 8.9 7.4 1.1 9.4 2.3 2.3 1 1 2 3 3 3 0 CHDCT2 (NUC038) domain Prominin PF05478.11 KNZ81441.1 - 5 5.0 8.6 10 3.9 8.6 1.4 1 1 0 1 1 1 0 Prominin Spc24 PF08286.11 KNZ81441.1 - 5.7 7.2 12.6 2.4 8.4 0.8 2.7 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 COG4 PF08318.12 KNZ81442.1 - 1.8e-94 316.6 0.0 1.2e-93 313.8 0.0 1.9 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 KNZ81442.1 - 0.005 15.8 0.8 0.011 14.7 0.0 1.9 2 1 1 3 3 3 1 RINT-1 / TIP-1 family PIF1 PF05970.14 KNZ81443.1 - 1.8e-11 43.9 0.0 2.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase Glyco_hydro_3_C PF01915.22 KNZ81445.1 - 9.8e-61 205.3 0.0 1.6e-60 204.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KNZ81445.1 - 2.8e-46 158.4 0.0 4.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KNZ81445.1 - 2e-22 79.1 0.2 4.3e-22 78.0 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 KNZ81445.1 - 1.7e-09 37.7 0.0 3.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.9 KNZ81445.1 - 0.0055 15.6 0.0 0.0084 15.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF2340 PF10209.9 KNZ81446.1 - 1.2e-43 148.4 0.5 1.9e-43 147.7 0.5 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Blt1 PF12754.7 KNZ81446.1 - 0.0025 18.2 0.4 0.0031 17.8 0.4 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Ubiquitin_4 PF18036.1 KNZ81446.1 - 0.13 12.3 0.1 2.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain CN_hydrolase PF00795.22 KNZ81447.1 - 2.1e-58 197.7 0.0 4.6e-58 196.6 0.0 1.5 1 1 1 2 2 2 1 Carbon-nitrogen hydrolase DnaJ PF00226.31 KNZ81447.1 - 2.2e-20 72.5 1.3 3.5e-20 71.9 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 KNZ81447.1 - 9.8e-11 41.9 0.0 2.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 DnaJ C terminal domain DAGK_cat PF00781.24 KNZ81448.1 - 1.9e-13 50.1 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.22 KNZ81449.1 - 1.8e-44 151.5 0.1 3.6e-44 150.5 0.1 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KNZ81449.1 - 1.5e-31 109.6 0.0 2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KNZ81449.1 - 4.1e-06 27.0 0.1 5.3e-05 23.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KNZ81449.1 - 8.2e-06 26.4 0.0 1.1e-05 26.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 KNZ81449.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 KNZ81449.1 - 0.034 13.8 0.3 0.11 12.1 0.1 1.9 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 KNZ81449.1 - 0.11 12.1 0.3 4.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase WD40 PF00400.32 KNZ81450.1 - 0.00066 20.4 0.6 0.042 14.7 0.1 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Fungal_trans PF04082.18 KNZ81451.1 - 5.2e-07 29.0 0.1 1.1e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ81451.1 - 0.081 13.1 3.5 0.16 12.2 3.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KNZ81452.1 - 5.5e-18 64.4 1.3 6.9e-18 64.1 1.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KNZ81452.1 - 0.0063 16.6 0.1 0.0091 16.1 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain BPL_C PF02237.17 KNZ81452.1 - 0.046 13.6 0.1 0.36 10.8 0.1 2.1 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Hfq PF17209.3 KNZ81452.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Glyco_hydro_63 PF03200.16 KNZ81454.1 - 2e-158 528.2 0.1 2.1e-157 524.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KNZ81454.1 - 1.1e-76 258.0 0.0 3.4e-76 256.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KNZ81454.1 - 0.00023 20.1 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Trehalase FH2 PF02181.23 KNZ81455.1 - 3.4e-66 223.9 6.3 3.4e-66 223.9 6.3 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 KNZ81455.1 - 7.7e-35 120.3 2.3 7.7e-35 120.3 2.3 2.7 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 KNZ81455.1 - 2e-33 115.5 1.5 3.4e-33 114.8 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain SCF PF02404.15 KNZ81455.1 - 0.047 13.0 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Stem cell factor PBP PF01161.20 KNZ81457.1 - 7.2e-11 42.5 0.0 1.1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein G-patch PF01585.23 KNZ81458.1 - 1.1e-13 50.8 1.8 2e-13 50.0 1.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KNZ81458.1 - 6e-05 23.1 2.1 6e-05 23.1 2.1 2.5 3 0 0 3 3 3 1 G-patch domain RED_N PF07808.13 KNZ81458.1 - 0.0023 17.5 1.0 0.0023 17.5 1.0 2.8 3 0 0 3 3 3 1 RED-like protein N-terminal region RRM_1 PF00076.22 KNZ81458.1 - 0.0044 16.8 0.6 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.8 KNZ81458.1 - 0.0068 16.7 0.5 0.015 15.6 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNZ81458.1 - 0.014 15.7 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 KNZ81458.1 - 0.069 13.6 0.5 0.16 12.5 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ81458.1 - 0.091 13.6 0.5 0.19 12.6 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-LYAR PF08790.11 KNZ81458.1 - 0.19 11.7 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger COQ7 PF03232.13 KNZ81459.1 - 4.3e-69 231.7 0.3 5e-69 231.5 0.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PUB PF09409.10 KNZ81461.1 - 9.9e-09 35.0 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 PUB domain DUF5039 PF16442.5 KNZ81461.1 - 0.042 13.4 0.3 0.057 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5039) DUF2992 PF11208.8 KNZ81461.1 - 1.6 9.0 7.2 0.22 11.7 2.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Porin_5 PF16930.5 KNZ81461.1 - 2.1 6.8 5.0 2.9 6.3 5.0 1.2 1 0 0 1 1 1 0 Putative porin PCI PF01399.27 KNZ81463.1 - 2.3e-10 40.9 0.0 1.7e-09 38.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain Tropomyosin_1 PF12718.7 KNZ81463.1 - 0.021 15.0 1.4 0.038 14.1 1.4 1.4 1 0 0 1 1 1 0 Tropomyosin like MarR_2 PF12802.7 KNZ81463.1 - 0.021 14.7 0.4 12 5.9 0.1 3.2 3 0 0 3 3 3 0 MarR family Pkinase PF00069.25 KNZ81464.1 - 2.3e-65 220.6 0.0 2.7e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81464.1 - 4.9e-32 111.2 0.0 6.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ81464.1 - 2.8e-07 30.1 0.0 5.5e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KNZ81464.1 - 0.006 15.6 0.1 0.0085 15.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KNZ81464.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KNZ81464.1 - 0.02 14.2 0.2 0.047 13.0 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.32 KNZ81465.1 - 0.0011 19.8 0.1 0.2 12.6 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Asp PF00026.23 KNZ81466.1 - 2.9e-109 365.3 0.1 3.4e-109 365.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ81466.1 - 1.2e-13 51.7 2.0 6.6e-12 46.0 2.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KNZ81466.1 - 3.7e-05 23.5 0.0 0.00054 19.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KNZ81466.1 - 0.0046 17.6 0.1 5.2 7.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KNZ81466.1 - 0.051 14.1 0.0 14 6.4 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Bromodomain PF00439.25 KNZ81467.1 - 6.3e-22 77.5 0.1 2.5e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Bromodomain Myb_DNA-binding PF00249.31 KNZ81467.1 - 0.0031 17.7 0.0 0.0093 16.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAT PF02259.23 KNZ81468.1 - 1.5e-64 218.4 5.9 2.3e-64 217.8 4.3 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 KNZ81468.1 - 5.3e-21 75.6 0.5 1.4e-20 74.2 0.1 1.9 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KNZ81468.1 - 0.043 13.6 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 FATC domain Thioredoxin PF00085.20 KNZ81469.1 - 8.7e-60 199.1 1.5 1.1e-30 105.6 0.1 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 KNZ81469.1 - 6.9e-37 127.1 0.2 1.4e-29 103.4 0.2 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 KNZ81469.1 - 1.5e-07 31.5 0.4 0.032 14.4 0.1 3.0 3 0 0 3 3 3 2 Thioredoxin-like WH2 PF02205.20 KNZ81469.1 - 2.6e-07 30.2 1.1 1.7e-06 27.6 0.8 2.2 2 0 0 2 2 2 1 WH2 motif AhpC-TSA PF00578.21 KNZ81469.1 - 2e-06 27.7 0.5 0.044 13.7 0.1 2.8 2 1 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 KNZ81469.1 - 8.1e-06 26.1 0.2 0.19 12.1 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KNZ81469.1 - 2.1e-05 25.0 0.3 0.08 13.4 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Redoxin PF08534.10 KNZ81469.1 - 3.3e-05 23.6 0.1 0.3 10.8 0.0 2.8 2 0 0 2 2 2 2 Redoxin OST3_OST6 PF04756.13 KNZ81469.1 - 0.00024 20.6 0.8 1.4 8.2 0.0 3.5 3 1 0 4 4 4 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KNZ81469.1 - 0.0057 15.7 0.5 0.015 14.3 0.5 1.7 1 1 0 1 1 1 1 Calsequestrin GCP_N_terminal PF17681.1 KNZ81470.1 - 7.8e-97 324.6 0.0 1.5e-96 323.7 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KNZ81470.1 - 4e-88 295.9 2.9 4e-88 295.9 2.9 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal TCTP PF00838.17 KNZ81471.1 - 1e-58 198.3 1.9 1.3e-58 198.0 1.9 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein GST_C_5 PF16865.5 KNZ81471.1 - 0.033 14.8 0.2 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain UTP15_C PF09384.10 KNZ81472.1 - 8e-50 168.4 0.1 1.2e-49 167.8 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KNZ81472.1 - 2.1e-26 91.6 4.7 0.00016 22.4 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ81472.1 - 4.3e-10 39.7 0.0 0.0045 17.3 0.0 5.0 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KNZ81472.1 - 0.0092 15.1 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region Cytochrom_D1 PF02239.16 KNZ81472.1 - 0.019 13.5 0.1 0.16 10.5 0.0 2.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 KNZ81472.1 - 0.064 11.9 0.2 2.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Frtz PF11768.8 KNZ81472.1 - 0.088 11.1 0.0 21 3.2 0.0 3.3 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz CTNNBL PF08216.11 KNZ81473.1 - 1.5e-34 118.2 0.0 5.9e-34 116.4 0.0 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Xpo1 PF08389.12 KNZ81473.1 - 0.0068 16.5 0.3 0.11 12.5 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein RIH_assoc PF08454.11 KNZ81473.1 - 0.015 15.1 2.1 8.7 6.3 0.0 3.4 3 1 0 3 3 3 0 RyR and IP3R Homology associated Arm PF00514.23 KNZ81473.1 - 0.13 12.4 0.5 4.7 7.4 0.1 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RRM_1 PF00076.22 KNZ81474.1 - 6.9e-16 57.8 0.0 1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L5e PF17144.4 KNZ81475.1 - 5.4e-78 260.6 0.0 8.8e-78 259.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KNZ81475.1 - 4.2e-36 123.8 1.3 4.2e-36 123.8 1.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 KNZ81475.1 - 0.042 14.2 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K_oxygenase PF13434.6 KNZ81475.1 - 0.086 12.0 0.9 0.1 11.7 0.2 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Med17 PF10156.9 KNZ81476.1 - 2.4e-30 105.7 0.0 3.6e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.18 KNZ81477.1 - 2.8e-18 65.9 0.0 4.6e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ81477.1 - 4.6e-05 23.4 9.9 7.8e-05 22.7 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GIT1_C PF12205.8 KNZ81477.1 - 0.12 12.5 0.2 2.9 8.1 0.1 2.6 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF1216 PF06746.11 KNZ81477.1 - 0.22 11.5 2.0 0.37 10.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) DUF4111 PF13427.6 KNZ81478.1 - 0.07 13.3 0.1 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) Snf7 PF03357.21 KNZ81479.1 - 6.7e-27 94.2 19.2 6.7e-27 94.2 19.2 1.6 1 1 0 1 1 1 1 Snf7 cwf21 PF08312.12 KNZ81479.1 - 0.32 11.2 6.9 1.1 9.4 6.9 1.9 1 1 0 1 1 1 0 cwf21 domain Metal_resist PF13801.6 KNZ81479.1 - 3 8.1 7.9 1.3 9.2 0.5 2.9 3 0 0 3 3 3 0 Heavy-metal resistance CENP-H PF05837.12 KNZ81479.1 - 4 7.9 17.5 0.14 12.6 2.9 3.0 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Iso_dh PF00180.20 KNZ81480.1 - 2.5e-101 339.3 0.0 3.2e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.19 KNZ81481.1 - 4.5e-99 331.9 0.0 7.9e-99 331.1 0.0 1.4 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 KNZ81481.1 - 6e-26 90.6 0.3 1.5e-25 89.4 0.3 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 KNZ81481.1 - 3.5e-24 84.6 0.0 7.4e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 KNZ81481.1 - 0.00024 21.2 0.1 0.12 12.6 0.0 3.0 3 0 0 3 3 3 2 Cold shock domain Rrp44_S1 PF17215.3 KNZ81481.1 - 0.0016 18.3 0.9 0.0041 17.0 0.0 2.2 2 1 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 KNZ81481.1 - 0.015 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain RRS1 PF04939.12 KNZ81481.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.9 3 0 0 3 3 3 0 Ribosome biogenesis regulatory protein (RRS1) Piwi PF02171.17 KNZ81482.1 - 2.1e-65 220.9 0.0 3.1e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KNZ81482.1 - 1.9e-22 80.4 0.0 3.2e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KNZ81482.1 - 7.9e-17 60.7 0.1 3.5e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KNZ81482.1 - 6.1e-15 55.3 0.0 1.5e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 KNZ81482.1 - 5.3e-13 49.0 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 KNZ81482.1 - 8.1e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 PAZ domain Mito_carr PF00153.27 KNZ81483.1 - 1.1e-62 208.0 1.6 5.3e-22 77.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KNZ81483.1 - 0.00057 19.3 0.1 0.05 13.2 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KNZ81483.1 - 0.00093 19.6 0.0 0.0026 18.2 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 KNZ81483.1 - 0.0017 18.1 0.5 0.086 12.8 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KNZ81483.1 - 0.017 14.6 0.5 0.11 12.0 0.1 2.2 2 0 0 2 2 2 0 EF hand SNARE_assoc PF09335.11 KNZ81484.1 - 0.0033 17.9 0.4 0.014 15.8 0.1 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein Ribosomal_L36e PF01158.18 KNZ81485.1 - 1.9e-39 133.8 3.7 2.3e-39 133.5 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 KNZ81485.1 - 0.014 14.9 0.2 0.017 14.6 0.2 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction CK_II_beta PF01214.18 KNZ81486.1 - 1.4e-57 194.5 0.2 3.1e-38 131.4 0.0 2.1 1 1 1 2 2 2 2 Casein kinase II regulatory subunit CRCB PF02537.15 KNZ81487.1 - 2.3e-28 98.4 19.9 4e-16 59.1 7.7 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) adh_short PF00106.25 KNZ81488.1 - 6.4e-25 87.8 0.0 2.5e-24 85.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ81488.1 - 2.7e-10 40.2 0.0 7.8e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ81488.1 - 3.7e-06 27.0 0.0 0.00026 21.0 0.0 2.2 1 1 0 1 1 1 1 KR domain ApbA PF02558.16 KNZ81488.1 - 0.0092 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 KNZ81488.1 - 0.018 14.4 0.0 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase YjeF_N PF03853.15 KNZ81488.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus ADH_zinc_N PF00107.26 KNZ81488.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.21 KNZ81488.1 - 0.056 12.9 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KNZ81488.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 KNZ81488.1 - 0.2 11.5 0.0 0.37 10.7 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding IBP39 PF11422.8 KNZ81489.1 - 0.033 14.0 0.0 0.057 13.2 0.0 1.3 1 1 0 1 1 1 0 Initiator binding protein 39 kDa DUF1282 PF06930.12 KNZ81489.1 - 0.072 12.9 3.4 0.096 12.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) VID27 PF08553.10 KNZ81490.1 - 2.6e-171 569.5 0.3 3.4e-171 569.1 0.3 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KNZ81490.1 - 5.1e-57 192.5 0.4 5.1e-57 192.5 0.4 3.1 2 1 1 3 3 3 2 VID27 N-terminal region VID27_PH PF17747.1 KNZ81490.1 - 1.7e-22 79.7 2.3 4.2e-22 78.5 2.3 1.7 1 0 0 1 1 1 1 VID27 PH-like domain DUF4894 PF16235.5 KNZ81493.1 - 0.076 13.4 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4894) gag-asp_proteas PF13975.6 KNZ81495.1 - 0.00075 20.0 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81495.1 - 0.017 15.8 0.0 0.031 14.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease RT_RNaseH PF17917.1 KNZ81496.1 - 3e-07 30.7 0.0 6.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ81496.1 - 1.5e-06 28.2 0.0 3.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ81499.1 - 1.3e-09 37.9 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ81499.1 - 1.3e-08 35.0 0.0 4.9e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RTA1 PF04479.13 KNZ81501.1 - 4.5e-54 183.2 6.4 6.6e-54 182.7 6.4 1.2 1 0 0 1 1 1 1 RTA1 like protein HisKA_7TM PF16927.5 KNZ81501.1 - 4.1 7.4 19.0 24 4.9 19.0 2.4 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase BTB_2 PF02214.22 KNZ81503.1 - 0.056 13.8 0.1 0.3 11.5 0.1 2.3 1 1 0 1 1 1 0 BTB/POZ domain Histidinol_dh PF00815.20 KNZ81504.1 - 5e-166 552.7 2.4 6.6e-166 552.4 2.4 1.1 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KNZ81504.1 - 8.7e-25 86.4 0.5 2e-24 85.2 0.5 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 KNZ81504.1 - 2.8e-12 46.9 1.2 4.1e-12 46.4 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase adh_short PF00106.25 KNZ81505.1 - 1.4e-41 142.1 0.0 1.7e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ81505.1 - 3.8e-32 111.7 0.0 4.5e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ81505.1 - 9.1e-14 51.8 0.1 7.3e-13 48.8 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KNZ81505.1 - 3.4e-05 23.8 0.0 5.6e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KNZ81505.1 - 3.5e-05 23.4 0.0 0.0068 15.9 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KNZ81505.1 - 0.15 11.6 0.1 0.63 9.6 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family Amidohydro_2 PF04909.14 KNZ81506.1 - 1.5e-31 110.2 0.1 2e-31 109.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Iso_dh PF00180.20 KNZ81508.1 - 3.7e-43 148.0 0.1 1.1e-25 90.5 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase DUF262 PF03235.14 KNZ81510.1 - 1.9e-09 38.0 0.1 5.2e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF262 Dcc1 PF09724.9 KNZ81511.1 - 3.1e-87 293.0 0.0 3.6e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 bZIP_C PF12498.8 KNZ81511.1 - 0.042 14.8 0.1 0.076 14.0 0.1 1.4 1 0 0 1 1 1 0 Basic leucine-zipper C terminal TFR_dimer PF04253.15 KNZ81512.1 - 1.1e-22 80.3 1.3 3.8e-20 72.2 0.0 2.4 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KNZ81512.1 - 3.9e-16 59.3 0.0 2e-15 57.0 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KNZ81512.1 - 2.9e-11 43.2 0.2 6.9e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 PA domain Cyclase PF04199.13 KNZ81512.1 - 0.012 15.9 0.1 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Putative cyclase Choline_kinase PF01633.20 KNZ81512.1 - 0.028 14.0 0.8 0.058 13.0 0.8 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nicastrin PF05450.15 KNZ81512.1 - 0.062 12.8 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Nicastrin Peptidase_M20 PF01546.28 KNZ81512.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Tho2 PF11262.8 KNZ81512.1 - 0.11 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 OmpH PF03938.14 KNZ81513.1 - 0.84 10.0 6.1 1.6 9.1 6.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Clat_adaptor_s PF01217.20 KNZ81514.1 - 1.9e-51 173.7 0.3 2.2e-51 173.5 0.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Gln-synt_C PF00120.24 KNZ81515.1 - 5.7e-17 61.7 0.0 8.3e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KNZ81515.1 - 1.1e-10 41.1 0.0 2.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF2264 PF10022.9 KNZ81516.1 - 2.3e-139 464.4 0.9 2.9e-139 464.1 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DnaJ PF00226.31 KNZ81517.1 - 1.3e-18 66.9 0.0 2.4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DNA_pol_phi PF04931.13 KNZ81518.1 - 0.00017 19.8 6.5 0.00023 19.4 6.5 1.1 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 KNZ81518.1 - 0.022 13.0 1.0 0.032 12.5 1.0 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 KNZ81518.1 - 0.029 13.7 5.7 0.048 13.0 5.7 1.3 1 0 0 1 1 1 0 BUD22 zf-RRN7 PF11781.8 KNZ81518.1 - 0.037 13.7 0.1 0.088 12.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nop14 PF04147.12 KNZ81518.1 - 3.1 5.9 13.9 4.4 5.4 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family EF-hand_3 PF09069.11 KNZ81520.1 - 0.0076 16.6 0.3 0.2 12.1 0.1 2.5 2 0 0 2 2 2 1 EF-hand Picorna_P3A PF06363.11 KNZ81520.1 - 0.033 14.0 0.6 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Picornaviridae P3A protein Filament PF00038.21 KNZ81520.1 - 0.19 11.2 5.5 0.12 11.9 0.5 2.4 2 1 0 2 2 2 0 Intermediate filament protein Ran-binding PF05508.11 KNZ81521.1 - 0.012 14.6 0.1 0.015 14.3 0.1 1.0 1 0 0 1 1 1 0 RanGTP-binding protein DUF5631 PF18645.1 KNZ81521.1 - 0.16 12.3 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5631) DASH_Dam1 PF08653.10 KNZ81521.1 - 0.17 11.7 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 TraC PF07820.12 KNZ81521.1 - 0.22 11.9 0.6 15 6.0 0.1 2.3 2 0 0 2 2 2 0 TraC-like protein HAD_2 PF13419.6 KNZ81522.1 - 5e-07 30.0 0.0 5.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KNZ81522.1 - 6.5e-07 29.9 0.0 7.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KNZ81522.1 - 5.5e-05 23.1 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Globin PF00042.22 KNZ81522.1 - 0.019 15.5 0.0 0.047 14.2 0.0 1.6 2 0 0 2 2 2 0 Globin Ribosomal_L6e PF01159.19 KNZ81523.1 - 7.3e-38 129.5 0.0 1.2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e AftA_N PF12250.8 KNZ81523.1 - 0.069 11.9 0.0 0.097 11.4 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal 60KD_IMP PF02096.20 KNZ81524.1 - 4e-10 39.8 0.0 5.3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Histone PF00125.24 KNZ81525.1 - 6.2e-45 152.8 0.3 9.8e-45 152.1 0.1 1.4 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KNZ81525.1 - 0.0016 18.8 0.2 0.0024 18.2 0.2 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KNZ81525.1 - 0.0056 16.9 0.6 0.01 16.1 0.2 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 KNZ81525.1 - 0.0078 16.3 0.1 0.014 15.5 0.1 1.5 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 KNZ81525.1 - 0.038 14.0 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF2833 PF11090.8 KNZ81526.1 - 0.052 13.9 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) TRAM_LAG1_CLN8 PF03798.16 KNZ81527.1 - 4.4e-34 118.0 27.4 4.4e-34 118.0 27.4 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KNZ81527.1 - 3.3e-12 45.9 0.2 3.3e-12 45.9 0.2 2.2 3 0 0 3 3 3 1 TRAM1-like protein EloA-BP1 PF15870.5 KNZ81528.1 - 3.4e-09 37.2 0.1 3.3e-07 30.7 0.1 2.2 1 1 0 1 1 1 1 ElonginA binding-protein 1 RNase_T PF00929.24 KNZ81528.1 - 3.5e-08 34.2 0.0 1.4e-07 32.2 0.0 2.0 1 1 0 1 1 1 1 Exonuclease CHORD PF04968.12 KNZ81528.1 - 0.005 17.5 5.7 0.011 16.5 5.7 1.6 1 0 0 1 1 1 1 CHORD zf-CCCH_2 PF14608.6 KNZ81528.1 - 0.01 16.3 2.5 0.034 14.6 2.5 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger UPF0183 PF03676.14 KNZ81529.1 - 6.2e-60 203.5 0.0 9.1e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) DNA_pol_E_B PF04042.16 KNZ81530.1 - 1.3e-44 152.1 0.8 2.2e-44 151.3 0.8 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KNZ81530.1 - 0.16 12.1 0.4 0.39 10.8 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Apt1 PF10351.9 KNZ81531.1 - 7.7e-47 160.2 0.3 1.5e-46 159.3 0.3 1.4 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 KNZ81531.1 - 7.9e-41 139.8 0.0 1.7e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_WPPW PF10359.9 KNZ81531.1 - 4.9e-32 111.4 0.0 4.6e-19 68.6 0.0 3.3 1 1 2 3 3 3 3 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KNZ81531.1 - 5.7e-31 107.5 0.0 2.9e-30 105.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 KNZ81531.1 - 6.2e-19 68.6 0.0 2.1e-18 66.9 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2985 PF11204.8 KNZ81532.1 - 8.5e-28 96.3 3.8 2.1e-27 95.1 3.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) OMPdecase PF00215.24 KNZ81533.1 - 6.4e-63 212.3 0.0 7.7e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.18 KNZ81534.1 - 2.4e-78 263.8 0.1 2.1e-75 254.1 0.0 2.7 2 2 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) FoP_duplication PF13865.6 KNZ81534.1 - 6.9 7.3 26.0 15 6.2 5.4 2.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 MFS_1 PF07690.16 KNZ81535.1 - 7.7e-28 97.4 20.7 3.8e-27 95.2 14.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KNZ81535.1 - 4.1e-08 32.5 3.9 1e-07 31.2 3.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 KNZ81535.1 - 0.0003 19.8 0.3 0.00064 18.8 0.3 1.6 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KNZ81535.1 - 0.0078 14.7 1.8 0.011 14.1 1.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly_transf_sug PF04488.15 KNZ81536.1 - 3.5e-21 75.6 0.0 6.9e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 KNZ81536.1 - 0.056 12.8 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PIN_4 PF13638.6 KNZ81537.1 - 4e-15 56.3 0.0 1.1e-14 54.8 0.0 1.7 1 1 0 1 1 1 1 PIN domain PIN_12 PF16289.5 KNZ81537.1 - 0.026 15.0 0.0 0.04 14.4 0.0 1.3 1 0 0 1 1 1 0 PIN domain UBA2_C PF16195.5 KNZ81537.1 - 0.065 13.9 0.9 0.13 12.9 0.9 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus CTD_bind PF04818.13 KNZ81538.1 - 5.5e-05 23.9 0.0 0.00011 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Zn-C2H2_12 PF18112.1 KNZ81538.1 - 0.0014 19.0 3.1 0.1 13.1 0.7 2.6 2 0 0 2 2 2 2 Autophagy receptor zinc finger-C2H2 domain CFIA_Pcf11 PF11526.8 KNZ81538.1 - 0.0084 16.6 0.0 0.066 13.7 0.0 2.3 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_11 PF16622.5 KNZ81538.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 KNZ81538.1 - 0.15 13.0 2.9 14 6.8 0.5 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 KNZ81538.1 - 0.22 11.3 1.7 2.6 7.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 KNZ81538.1 - 7.1 6.8 6.1 14 5.8 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_L6 PF00347.23 KNZ81539.1 - 2.5e-28 98.6 5.3 8.2e-16 58.5 2.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CBM_4_9 PF02018.17 KNZ81539.1 - 0.061 13.6 0.1 0.22 11.8 0.0 1.8 1 1 1 2 2 2 0 Carbohydrate binding domain ICMT PF04140.14 KNZ81540.1 - 2.3e-24 85.6 0.7 3.9e-24 84.9 0.7 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KNZ81540.1 - 2.5e-10 40.7 3.0 2.6e-10 40.6 2.0 1.5 1 1 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 KNZ81540.1 - 4.4e-05 23.1 0.7 6.7e-05 22.5 0.7 1.4 1 0 0 1 1 1 1 NnrU protein GTP_EFTU PF00009.27 KNZ81541.1 - 1.2e-51 175.0 0.0 1.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KNZ81541.1 - 1.1e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KNZ81541.1 - 8.4e-13 48.2 0.0 4.7e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ81541.1 - 8.3e-06 26.1 0.0 1.9e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KNZ81541.1 - 6.5e-05 23.0 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Phage_int_SAM_3 PF14659.6 KNZ81541.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain SRPRB PF09439.10 KNZ81541.1 - 0.034 13.6 0.1 0.091 12.2 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Saw1 PF11561.8 KNZ81542.1 - 0.1 12.2 0.1 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 Single strand annealing-weakened 1 DUF4278 PF14105.6 KNZ81542.1 - 0.11 12.9 0.0 0.94 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4278) NAD_binding_1 PF00175.21 KNZ81543.1 - 8.8e-10 39.2 0.0 8.3e-09 36.1 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KNZ81543.1 - 9.4e-07 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KNZ81543.1 - 7.6e-05 22.9 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain ADH_zinc_N PF00107.26 KNZ81544.1 - 3.7e-22 78.7 0.0 5.5e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ81544.1 - 2.3e-21 75.7 0.2 5.2e-21 74.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 KNZ81544.1 - 3.8e-07 29.8 0.2 0.00034 20.2 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KNZ81544.1 - 6.5e-05 22.3 0.3 0.00011 21.6 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KNZ81544.1 - 0.0001 23.3 0.1 0.00037 21.6 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 KNZ81544.1 - 0.0019 18.9 0.0 0.0039 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KNZ81544.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PrmA PF06325.13 KNZ81544.1 - 0.029 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KNZ81544.1 - 0.052 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KNZ81544.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 KNZ81544.1 - 0.11 13.1 0.0 0.22 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 KNZ81545.1 - 3.5e-35 121.6 0.0 4.6e-33 114.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81545.1 - 2e-25 89.5 0.0 6.5e-23 81.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pentapeptide_2 PF01469.18 KNZ81545.1 - 0.049 13.5 0.5 0.084 12.8 0.5 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (8 copies) Meth_synt_2 PF01717.18 KNZ81546.1 - 2.1e-148 493.9 0.0 1.2e-144 481.5 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KNZ81546.1 - 4.3e-117 391.1 0.0 1.3e-110 369.8 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain FAD_binding_7 PF03441.14 KNZ81547.1 - 2.8e-73 245.7 1.1 6.5e-73 244.5 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KNZ81547.1 - 3.6e-34 118.2 0.0 6e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase YycC PF14174.6 KNZ81547.1 - 0.052 13.3 0.1 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 YycC-like protein eRF1_1 PF03463.15 KNZ81548.1 - 3.5e-35 120.8 0.0 5.5e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 KNZ81548.1 - 3.4e-23 82.3 0.0 6.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 KNZ81548.1 - 7e-18 65.2 0.0 1.2e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 Phosducin PF02114.16 KNZ81549.1 - 0.0011 18.0 0.6 0.0017 17.4 0.5 1.4 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 KNZ81549.1 - 0.0038 17.2 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF5127 PF17168.4 KNZ81550.1 - 1.4e-74 250.7 0.1 3.2e-74 249.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 KNZ81550.1 - 5.2e-63 212.4 0.9 1.2e-62 211.3 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KNZ81550.1 - 1.2e-53 181.4 0.2 5.8e-53 179.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF4964 PF16334.5 KNZ81550.1 - 3.6e-06 26.4 0.1 1.2e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DUF5127 PF17168.4 KNZ81551.1 - 1.8e-77 260.2 4.8 3.7e-77 259.2 4.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KNZ81551.1 - 5.2e-77 257.4 0.2 3.6e-76 254.7 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KNZ81551.1 - 2.9e-68 229.5 3.2 2.9e-68 229.5 3.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 KNZ81551.1 - 8.8e-11 41.2 0.4 7.3e-10 38.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4964) Glyco_hydro_18 PF00704.28 KNZ81552.1 - 1e-50 173.2 0.0 1.2e-50 173.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5127 PF17168.4 KNZ81553.1 - 5.7e-77 258.5 9.2 9.5e-77 257.8 9.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 KNZ81553.1 - 2.9e-65 219.2 0.1 2.9e-65 219.2 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 KNZ81553.1 - 6.4e-65 218.6 6.6 6.9e-65 218.5 2.3 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1793) Wtap PF17098.5 KNZ81554.1 - 1.1e-15 57.9 6.3 3.3e-14 53.1 6.3 2.1 1 1 0 1 1 1 1 WTAP/Mum2p family ALMT PF11744.8 KNZ81554.1 - 0.033 13.0 0.5 0.042 12.7 0.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Lebercilin PF15619.6 KNZ81554.1 - 0.041 13.5 5.9 0.076 12.7 1.0 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease SKA1 PF07160.12 KNZ81554.1 - 0.11 12.3 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FAM76 PF16046.5 KNZ81554.1 - 0.13 11.5 0.5 0.92 8.8 0.1 2.1 2 0 0 2 2 2 0 FAM76 protein TMF_DNA_bd PF12329.8 KNZ81554.1 - 0.62 10.1 5.0 14 5.7 0.1 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 KNZ81554.1 - 0.74 8.6 3.0 0.44 9.4 0.7 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 KNZ81554.1 - 0.79 10.7 5.0 0.93 10.4 0.9 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Ank_2 PF12796.7 KNZ81556.1 - 6.9e-23 81.0 0.1 1.8e-15 57.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KNZ81556.1 - 1.4e-19 70.2 1.1 1.6e-06 28.5 0.0 5.1 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ81556.1 - 2e-18 66.2 0.5 3.7e-09 36.7 0.0 4.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ81556.1 - 8.2e-14 50.4 0.4 0.00036 20.8 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KNZ81556.1 - 1.3e-12 47.5 0.4 5.9e-05 23.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat MFS_1 PF07690.16 KNZ81557.1 - 3.2e-13 49.3 14.1 1.4e-05 24.2 12.9 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KNZ81557.1 - 9.7e-05 21.4 1.8 9.7e-05 21.4 1.8 1.8 2 0 0 2 2 2 1 MFS_1 like family Diphthami_syn_2 PF01902.17 KNZ81558.1 - 6.1e-40 137.0 0.0 4.9e-32 111.2 0.0 2.2 1 1 1 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 KNZ81558.1 - 5.9e-22 77.9 0.0 3.7e-10 39.9 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP tRNA_synthFbeta PF17759.1 KNZ81559.1 - 3.1e-48 164.0 0.0 4.8e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KNZ81559.1 - 7.3e-30 103.0 0.0 7.6e-29 99.8 0.0 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KNZ81559.1 - 4.8e-26 91.5 0.1 1e-25 90.4 0.1 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KNZ81559.1 - 1.5e-19 70.0 0.0 1.4e-15 57.3 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.20 KNZ81559.1 - 0.021 14.3 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2370 PF10176.9 KNZ81562.1 - 2.7e-75 252.9 0.0 4.1e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF5531 PF17671.1 KNZ81562.1 - 1.1 9.2 3.0 0.44 10.4 0.2 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5531) Acetyltransf_1 PF00583.25 KNZ81563.1 - 1.3e-10 41.5 0.1 2.4e-10 40.7 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KNZ81563.1 - 4.4e-09 36.6 0.2 1.2e-08 35.2 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KNZ81563.1 - 4.2e-08 33.2 0.0 7.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KNZ81563.1 - 1.3e-05 25.0 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KNZ81563.1 - 0.00013 22.7 0.1 0.00027 21.6 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KNZ81563.1 - 0.0019 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KNZ81563.1 - 0.0021 18.1 0.0 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 KNZ81563.1 - 0.091 12.2 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase ThrE PF06738.12 KNZ81564.1 - 5.1e-43 147.2 6.4 5.1e-43 147.2 6.4 2.5 2 1 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KNZ81564.1 - 1.3e-05 25.3 7.4 1.3e-05 25.3 7.4 3.1 2 2 0 2 2 2 2 Threonine/Serine exporter, ThrE tRNA-synt_2d PF01409.20 KNZ81565.1 - 3.2e-85 285.5 0.0 6.3e-84 281.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KNZ81565.1 - 2.4e-16 59.7 0.1 5.5e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KNZ81565.1 - 1.6e-10 40.8 0.0 1.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KNZ81565.1 - 0.0013 17.9 0.4 0.021 13.9 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 KNZ81565.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) gag-asp_proteas PF13975.6 KNZ81566.1 - 1.6e-07 31.8 0.0 2.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81566.1 - 4.2e-06 27.3 0.0 7.3e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 KNZ81566.1 - 0.0037 17.0 0.1 0.0048 16.7 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease EB1_binding PF05937.11 KNZ81569.1 - 0.01 16.4 0.3 0.012 16.2 0.3 1.0 1 0 0 1 1 1 0 EB-1 Binding Domain DUF3801 PF12687.7 KNZ81569.1 - 0.027 14.5 0.1 0.029 14.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) NOA36 PF06524.12 KNZ81570.1 - 9 5.5 7.1 17 4.6 7.1 1.4 1 0 0 1 1 1 0 NOA36 protein S4_2 PF13275.6 KNZ81571.1 - 0.054 13.3 1.3 5.9 6.8 1.7 2.2 2 0 0 2 2 2 0 S4 domain OGFr_N PF04664.13 KNZ81573.1 - 2.1e-58 197.3 0.0 2.6e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Sec1 PF00995.23 KNZ81574.1 - 1.2e-116 391.3 0.0 3e-116 389.9 0.0 1.6 1 1 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.12 KNZ81574.1 - 8.9e-80 267.7 0.1 1.3e-79 267.1 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KNZ81574.1 - 9.3e-22 77.2 0.2 9.3e-22 77.2 0.2 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) EF-hand_14 PF17959.1 KNZ81574.1 - 0.043 14.2 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain RasGEF PF00617.19 KNZ81576.1 - 3e-49 167.6 0.0 6.8e-49 166.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KNZ81576.1 - 3.7e-20 72.1 0.0 1.2e-19 70.5 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 KNZ81576.1 - 2.8e-13 49.5 0.0 5.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KNZ81576.1 - 5.5e-12 45.2 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KNZ81576.1 - 8.3e-12 44.5 0.0 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain F-box PF00646.33 KNZ81577.1 - 7.2e-06 25.7 0.1 2e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KNZ81577.1 - 4.9e-05 23.2 0.2 0.00012 21.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like EF_assoc_2 PF08356.12 KNZ81578.1 - 1e-35 121.6 0.0 2.3e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KNZ81578.1 - 1.2e-29 101.7 1.0 2.7e-29 100.6 1.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KNZ81578.1 - 9e-29 100.2 0.0 2.5e-22 79.2 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KNZ81578.1 - 1.2e-16 61.1 0.0 2.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 KNZ81578.1 - 1.2e-09 37.4 0.2 0.0003 20.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain VWA PF00092.28 KNZ81578.1 - 1.2e-09 38.6 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Arf PF00025.21 KNZ81578.1 - 3.8e-09 36.2 0.0 0.00025 20.5 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_7 PF13499.6 KNZ81578.1 - 7.2e-09 36.0 0.6 0.0021 18.4 0.0 3.1 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 KNZ81578.1 - 7.3e-09 34.6 1.5 0.0014 18.1 0.0 2.7 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 KNZ81578.1 - 1.6e-07 31.4 0.1 0.0005 20.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_5 PF13202.6 KNZ81578.1 - 3e-06 26.5 3.5 0.0089 15.5 0.1 2.8 2 0 0 2 2 2 2 EF hand VWA_2 PF13519.6 KNZ81578.1 - 1.1e-05 26.0 0.0 3.2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain EF-hand_10 PF14788.6 KNZ81578.1 - 0.00038 20.2 1.3 0.011 15.6 0.1 2.5 2 0 0 2 2 2 1 EF hand AAA_16 PF13191.6 KNZ81578.1 - 0.0014 19.1 0.1 0.24 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KNZ81578.1 - 0.0024 18.4 0.1 0.055 14.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 KNZ81578.1 - 0.0048 17.4 0.0 0.77 10.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 KNZ81578.1 - 0.0052 17.2 0.0 0.5 10.8 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KNZ81578.1 - 0.0053 16.7 0.3 0.42 10.5 0.0 3.2 4 0 0 4 4 4 1 RsgA GTPase SPARC_Ca_bdg PF10591.9 KNZ81578.1 - 0.0079 16.5 0.0 2.3 8.6 0.0 2.8 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region AAA_22 PF13401.6 KNZ81578.1 - 0.011 16.1 0.0 0.87 9.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 KNZ81578.1 - 0.019 14.8 0.2 4.8 7.1 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair AAA_29 PF13555.6 KNZ81578.1 - 0.023 14.5 0.3 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AIG1 PF04548.16 KNZ81578.1 - 0.037 13.3 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Septin PF00735.18 KNZ81578.1 - 0.039 13.2 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 KNZ81578.1 - 0.052 13.3 0.0 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KNZ81578.1 - 0.054 13.4 0.1 5 7.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 KNZ81578.1 - 0.069 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 KNZ81578.1 - 0.074 13.3 0.0 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Tautomerase PF01361.21 KNZ81578.1 - 0.14 12.1 0.1 0.63 10.0 0.0 2.2 2 0 0 2 2 1 0 Tautomerase enzyme AAA_25 PF13481.6 KNZ81578.1 - 0.14 11.7 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain MCM PF00493.23 KNZ81578.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain VirE PF05272.11 KNZ81578.1 - 0.18 11.5 0.0 8 6.1 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E AAA_33 PF13671.6 KNZ81578.1 - 0.19 11.9 0.1 2.4 8.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 KNZ81578.1 - 0.67 10.0 2.0 17 5.4 0.0 3.1 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KNZ81578.1 - 1.3 8.8 3.1 1.2e+02 2.3 0.0 3.8 3 1 2 5 5 5 0 Conserved hypothetical ATP binding protein Baculo_LEF5_C PF11792.8 KNZ81579.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain HSP20 PF00011.21 KNZ81581.1 - 1.6e-05 25.0 0.0 0.00053 20.1 0.0 2.0 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ81581.1 - 0.0092 15.5 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Chromo PF00385.24 KNZ81584.1 - 2.9e-14 52.7 0.1 3.5e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KNZ81584.1 - 0.05 13.8 0.1 0.071 13.3 0.1 1.2 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 gag-asp_proteas PF13975.6 KNZ81587.1 - 0.052 14.1 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ81587.1 - 0.14 12.8 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease DUF924 PF06041.11 KNZ81588.1 - 0.0067 16.6 0.6 0.011 15.9 0.6 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) KH_1 PF00013.29 KNZ81591.1 - 7.8e-08 32.0 0.8 0.00029 20.6 0.2 2.7 2 1 0 2 2 2 2 KH domain Trp_repressor PF01371.19 KNZ81591.1 - 0.075 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein CBM_19 PF03427.13 KNZ81592.1 - 0.00021 21.2 0.8 0.00021 21.2 0.8 3.4 3 1 1 4 4 4 1 Carbohydrate binding domain (family 19) FTR1 PF03239.14 KNZ81593.1 - 5.6e-62 209.7 15.9 7e-62 209.3 15.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3481 PF11980.8 KNZ81593.1 - 4.3 7.1 5.2 4.4 7.1 1.4 2.5 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Cu-oxidase PF00394.22 KNZ81594.1 - 1.2e-36 126.3 0.0 8e-35 120.3 0.1 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ81594.1 - 1.4e-36 125.2 3.8 2.3e-33 114.8 0.2 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ81594.1 - 8.1e-33 113.0 2.1 4e-32 110.7 0.3 2.9 3 1 0 4 4 4 1 Multicopper oxidase HIG_1_N PF04588.13 KNZ81595.1 - 2.9e-20 72.2 0.6 4.1e-20 71.7 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region TMEM101 PF15111.6 KNZ81595.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 TMEM101 protein family DUF4336 PF14234.6 KNZ81596.1 - 3.8e-08 32.9 0.1 0.0054 16.0 0.1 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Hira PF07569.11 KNZ81597.1 - 1.3e-54 185.3 0.0 1.3e-54 185.3 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 KNZ81597.1 - 4.1e-22 78.1 17.7 4.7e-05 24.1 0.1 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ81597.1 - 8.3e-12 45.3 0.5 0.071 13.4 0.0 6.1 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 KNZ81597.1 - 8.3e-06 25.4 0.3 3.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region MFS_1 PF07690.16 KNZ81598.1 - 2.5e-12 46.4 19.1 3.4e-12 46.0 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YoqO PF14037.6 KNZ81598.1 - 0.17 12.5 1.3 0.49 10.9 0.1 2.4 3 0 0 3 3 3 0 YoqO-like protein zf-PARP PF00645.18 KNZ81599.1 - 7.3e-24 84.4 0.1 7.3e-24 84.4 0.1 2.7 3 1 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ThylakoidFormat PF11264.8 KNZ81600.1 - 0.09 12.5 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein p450 PF00067.22 KNZ81601.1 - 2e-51 175.2 0.0 3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ni_hydr_CYTB PF01292.20 KNZ81601.1 - 0.011 15.4 0.1 0.021 14.4 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Ribosomal_S26e PF01283.19 KNZ81602.1 - 7e-53 177.6 8.5 8.2e-53 177.4 8.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KNZ81602.1 - 0.026 14.5 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 Zinc binding domain Pkinase PF00069.25 KNZ81604.1 - 5.7e-64 216.0 0.0 7.5e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81604.1 - 7.5e-31 107.3 0.0 1e-30 106.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ81604.1 - 0.00047 19.2 0.0 0.00071 18.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain CCM2_C PF16545.5 KNZ81606.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology P53_C PF11619.8 KNZ81606.1 - 0.16 12.1 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain NUDIX PF00293.28 KNZ81607.1 - 1.2e-08 35.0 0.2 1.9e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain DAO PF01266.24 KNZ81608.1 - 1e-33 117.4 0.6 1.7e-33 116.7 0.6 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KNZ81608.1 - 0.00038 19.8 0.0 0.0049 16.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ81608.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KNZ81608.1 - 0.0059 15.9 0.3 0.0094 15.2 0.3 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KNZ81608.1 - 0.01 16.1 0.3 0.037 14.3 0.5 1.8 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KNZ81608.1 - 0.03 14.9 1.6 0.068 13.7 1.6 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 KNZ81608.1 - 0.031 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KNZ81608.1 - 0.038 14.4 0.0 0.059 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 KNZ81608.1 - 0.042 13.3 0.2 0.076 12.5 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KNZ81608.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KNZ81608.1 - 0.23 10.1 0.4 0.32 9.6 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 KNZ81608.1 - 0.32 10.5 1.0 0.56 9.8 1.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 KNZ81609.1 - 1.5e-28 100.4 4.0 4e-27 95.7 4.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ81609.1 - 0.00041 19.6 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KNZ81609.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 KNZ81609.1 - 0.015 15.8 0.2 0.024 15.0 0.2 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 KNZ81609.1 - 0.05 12.9 0.1 0.077 12.3 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KNZ81609.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glycos_transf_1 PF00534.20 KNZ81610.1 - 2.4e-23 82.5 0.0 3.7e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KNZ81610.1 - 3.8e-21 75.9 0.0 7.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KNZ81610.1 - 2.9e-05 24.1 0.0 8.7e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 PIGA PF08288.12 KNZ81610.1 - 3e-05 24.5 0.8 0.00018 22.0 0.2 2.7 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_2 PF13524.6 KNZ81610.1 - 0.0035 17.7 0.0 0.0073 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Abhydrolase_1 PF00561.20 KNZ81611.1 - 4.3e-18 65.9 0.0 5.7e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KNZ81611.1 - 2.2e-10 41.5 0.4 3.2e-10 41.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ81611.1 - 4.9e-07 29.2 0.2 1.6e-05 24.3 0.0 2.4 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KNZ81611.1 - 0.064 13.1 0.0 1.8 8.3 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FA_desaturase PF00487.24 KNZ81612.1 - 5.2e-11 42.9 3.9 5.9e-11 42.7 3.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase HLH PF00010.26 KNZ81613.1 - 3e-05 23.9 0.0 0.00031 20.6 0.0 2.4 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain AT_hook PF02178.19 KNZ81613.1 - 0.43 10.6 7.3 1.2 9.3 7.3 1.8 1 0 0 1 1 1 0 AT hook motif WW PF00397.26 KNZ81615.1 - 6.8e-09 35.7 1.8 1.4e-08 34.7 1.8 1.6 1 0 0 1 1 1 1 WW domain UNC-50 PF05216.13 KNZ81616.1 - 5.9e-86 287.6 15.4 6.7e-86 287.4 15.4 1.0 1 0 0 1 1 1 1 UNC-50 family ADSL_C PF10397.9 KNZ81617.1 - 3.4e-16 59.5 0.0 6.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Lyase_1 PF00206.20 KNZ81617.1 - 8.3e-10 38.5 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Lyase CorA PF01544.18 KNZ81618.1 - 7.5e-10 38.6 4.5 1.3e-09 37.8 4.5 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 KNZ81618.1 - 0.00059 18.9 0.1 0.00082 18.4 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KNZ81618.1 - 0.022 14.0 0.1 0.03 13.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB ThrE PF06738.12 KNZ81618.1 - 0.055 12.8 2.7 0.12 11.7 0.6 2.0 1 1 1 2 2 2 0 Putative threonine/serine exporter GRA6 PF05084.13 KNZ81620.1 - 0.0046 16.9 1.6 0.0083 16.1 0.7 1.7 1 1 0 1 1 1 1 Granule antigen protein (GRA6) Amnionless PF14828.6 KNZ81620.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.10 KNZ81620.1 - 0.17 11.3 4.5 0.46 9.9 4.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 KNZ81620.1 - 0.22 12.4 0.3 1.2 10.0 0.0 2.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 KNZ81620.1 - 0.33 10.9 0.7 0.61 10.0 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain BTB PF00651.31 KNZ81621.1 - 1.7e-11 44.3 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Oxysterol_BP PF01237.18 KNZ81623.1 - 6.2e-39 133.9 3.0 1.6e-24 86.4 0.3 3.0 2 1 0 2 2 2 2 Oxysterol-binding protein DUF5589 PF17672.1 KNZ81623.1 - 0.0076 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5589) Glyco_hydro_16 PF00722.21 KNZ81624.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 tRNA-synt_1 PF00133.22 KNZ81625.1 - 6.1e-147 490.5 0.0 7.8e-147 490.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KNZ81625.1 - 3.2e-19 68.9 0.1 9.1e-14 51.0 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KNZ81625.1 - 9e-19 67.9 0.1 1.7e-18 67.1 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KNZ81625.1 - 0.0015 18.0 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain RecR PF02132.15 KNZ81625.1 - 0.12 11.9 4.7 0.36 10.4 4.7 1.7 1 0 0 1 1 1 0 RecR protein zinc_ribbon_9 PF14369.6 KNZ81625.1 - 0.18 12.1 6.6 0.4 11.0 6.6 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-FPG_IleRS PF06827.14 KNZ81625.1 - 0.26 11.2 9.5 2.1 8.3 9.4 2.3 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS ProRS-C_1 PF09180.11 KNZ81627.1 - 3.7e-26 91.1 0.1 7.4e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 KNZ81627.1 - 6.1e-17 61.6 0.0 1.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KNZ81627.1 - 2.3e-16 60.3 0.0 4.2e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 KNZ81627.1 - 3.3e-13 49.8 0.0 6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain zf-ribbon_3 PF13248.6 KNZ81627.1 - 0.17 11.3 0.3 0.33 10.4 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 KNZ81627.1 - 0.21 11.7 0.1 0.45 10.7 0.1 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Cyclin_N PF00134.23 KNZ81628.1 - 1.7e-45 153.8 2.0 5.1e-45 152.3 0.9 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KNZ81628.1 - 3.1e-25 88.6 0.1 6.9e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Band_7 PF01145.25 KNZ81629.1 - 2e-24 86.6 0.0 2e-24 86.6 0.0 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family DUF5588 PF17826.1 KNZ81629.1 - 0.005 15.8 1.4 0.22 10.4 1.9 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5588) Band_7_1 PF13421.6 KNZ81629.1 - 0.0099 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family zf-C2H2_jaz PF12171.8 KNZ81630.1 - 1.7e-07 31.3 14.0 0.00051 20.3 0.0 4.5 3 1 1 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C3HC4_3 PF13920.6 KNZ81630.1 - 3.9e-07 29.8 9.5 3.9e-07 29.8 9.5 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KNZ81630.1 - 2.4e-06 27.3 14.3 2.4e-06 27.3 14.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ81630.1 - 9.5e-06 25.9 13.3 9.5e-06 25.9 13.3 3.3 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 KNZ81630.1 - 1e-05 25.3 14.3 1e-05 25.3 14.3 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 KNZ81630.1 - 1.8e-05 25.0 9.2 0.046 14.1 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-RING_5 PF14634.6 KNZ81630.1 - 6e-05 22.9 22.5 0.00011 22.1 12.0 3.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C2H2_4 PF13894.6 KNZ81630.1 - 0.0014 19.3 19.1 0.069 14.0 0.0 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger Prok-RING_4 PF14447.6 KNZ81630.1 - 0.0014 18.4 12.4 0.0014 18.4 12.4 3.6 2 2 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KNZ81630.1 - 0.0035 17.3 10.6 0.0035 17.3 10.6 2.9 3 2 0 3 3 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 KNZ81630.1 - 0.011 16.0 8.7 0.011 16.0 8.7 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-DBF PF07535.12 KNZ81630.1 - 0.027 14.6 7.9 0.38 10.9 0.6 2.7 1 1 1 2 2 2 0 DBF zinc finger zf-RING_6 PF14835.6 KNZ81630.1 - 0.3 11.0 8.8 0.94 9.4 8.8 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.6 KNZ81630.1 - 0.51 10.4 14.1 2.5 8.2 0.0 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 KNZ81630.1 - 1.1 9.2 6.0 3 7.8 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 KNZ81631.1 - 3.8e-09 36.6 2.3 0.00042 20.5 0.0 2.6 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KNZ81631.1 - 3.5e-06 27.2 0.2 0.038 14.4 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KNZ81631.1 - 0.0016 18.4 1.0 2.1 8.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KNZ81631.1 - 0.0031 18.2 10.2 0.057 14.3 0.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-DBF PF07535.12 KNZ81631.1 - 0.016 15.3 7.7 0.29 11.3 0.5 2.7 1 1 1 2 2 2 0 DBF zinc finger zf-C2H2 PF00096.26 KNZ81631.1 - 0.033 14.6 7.0 3.4 8.3 2.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nro1 PF12753.7 KNZ81631.1 - 0.075 12.0 1.1 1.1 8.1 1.0 2.0 1 1 1 2 2 2 0 Nuclear pore complex subunit Nro1 zf-C2H2_2 PF12756.7 KNZ81631.1 - 0.4 11.0 5.7 2.1 8.7 1.7 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) CBS PF00571.28 KNZ81632.1 - 4.6e-07 30.2 0.0 0.0033 17.8 0.0 2.2 2 0 0 2 2 2 2 CBS domain Mlh1_C PF16413.5 KNZ81633.1 - 6.1e-89 298.0 0.0 6.1e-89 298.0 0.0 2.2 3 0 0 3 3 3 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KNZ81633.1 - 4.1e-22 78.1 0.1 2.9e-21 75.4 0.1 2.3 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KNZ81633.1 - 2.4e-12 46.9 0.0 5.5e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KNZ81633.1 - 5.3e-09 36.6 0.0 1.6e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOR2-PAG1_N PF14222.6 KNZ81634.1 - 1.3e-152 509.6 0.0 3.2e-152 508.3 0.0 1.7 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KNZ81634.1 - 1.5e-88 296.9 1.8 3.5e-88 295.7 1.8 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KNZ81634.1 - 2.6e-17 61.9 0.1 1.3e-10 39.7 0.0 3.1 3 0 0 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 KNZ81634.1 - 0.21 11.6 0.5 0.97 9.5 0.1 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 RPN1_RPN2_N PF17781.1 KNZ81635.1 - 4.1e-110 368.0 0.0 7.2e-110 367.2 0.0 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KNZ81635.1 - 8.4e-28 96.2 0.1 1.6e-27 95.3 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KNZ81635.1 - 8e-21 73.4 18.7 0.00019 21.7 0.0 9.5 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KNZ81635.1 - 2.1e-05 24.8 0.0 0.26 11.7 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats THOC2_N PF16134.5 KNZ81635.1 - 0.00095 17.9 0.1 0.0018 17.0 0.1 1.4 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus HA2 PF04408.23 KNZ81635.1 - 0.093 13.0 0.2 0.5 10.7 0.2 2.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) IFRD PF05004.13 KNZ81635.1 - 0.36 9.9 3.3 0.17 10.9 0.1 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) PQ-loop PF04193.14 KNZ81636.1 - 1.8e-17 62.8 17.7 2.8e-10 39.8 1.5 3.5 3 0 0 3 3 3 2 PQ loop repeat Fig1 PF12351.8 KNZ81636.1 - 7.4 6.5 13.1 6.9 6.6 0.5 2.5 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 PP2C PF00481.21 KNZ81637.1 - 1.2e-15 57.8 0.0 2.9e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KNZ81637.1 - 0.00087 19.3 0.0 0.028 14.4 0.0 2.7 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Cyclin_N PF00134.23 KNZ81639.1 - 2e-40 137.5 0.6 8.8e-40 135.4 0.5 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KNZ81639.1 - 1e-22 80.5 0.0 1.8e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain FA_desaturase PF00487.24 KNZ81640.1 - 1.5e-15 57.7 23.3 2.8e-15 56.8 23.3 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KNZ81640.1 - 3.2e-12 46.4 0.0 6.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ion_trans_2 PF07885.16 KNZ81641.1 - 5.7e-34 115.9 33.0 3.1e-19 68.7 11.7 3.3 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 KNZ81641.1 - 7.2e-05 22.7 6.7 0.0025 17.7 1.4 2.8 2 2 0 2 2 2 2 Ligand-gated ion channel Ion_trans PF00520.31 KNZ81641.1 - 0.00068 18.9 30.1 0.0012 18.1 2.1 3.1 2 1 1 3 3 3 2 Ion transport protein EMC3_TMCO1 PF01956.16 KNZ81641.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DUF21 PF01595.20 KNZ81641.1 - 0.51 10.0 4.7 1.7 8.3 1.8 2.7 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain rve PF00665.26 KNZ81642.1 - 0.00029 21.0 0.0 0.0003 21.0 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain PIF1 PF05970.14 KNZ81643.1 - 2.5e-39 135.5 0.0 2.9e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ81643.1 - 0.0019 17.9 0.0 0.0051 16.5 0.0 1.7 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal UvrD_C_2 PF13538.6 KNZ81643.1 - 0.048 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.14 KNZ81644.1 - 8.3e-36 123.9 0.0 1.2e-35 123.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ81644.1 - 0.0031 17.3 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ81644.1 - 0.0041 17.1 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ81644.1 - 0.0057 17.1 0.0 0.0082 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF2791 PF10923.8 KNZ81644.1 - 0.017 14.0 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.18 KNZ81644.1 - 0.033 13.9 0.1 0.052 13.3 0.1 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ribosomal_S11 PF00411.19 KNZ81644.1 - 0.04 14.3 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S11 AAA_25 PF13481.6 KNZ81644.1 - 0.1 12.2 0.6 0.27 10.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain Helitron_like_N PF14214.6 KNZ81645.1 - 1.1e-22 81.2 0.0 1.4e-22 80.9 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DEC-1_N PF04625.13 KNZ81646.1 - 0.1 11.6 10.0 0.11 11.4 10.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Xan_ur_permease PF00860.20 KNZ81647.1 - 3.6e-53 180.7 30.0 1.5e-40 139.2 10.9 2.1 2 0 0 2 2 2 2 Permease family Hema_stalk PF08720.10 KNZ81647.1 - 2 8.1 4.8 9.5 5.9 0.2 3.1 3 0 0 3 3 3 0 Influenza C hemagglutinin stalk Hist_deacetyl PF00850.19 KNZ81648.1 - 3.7e-82 276.2 0.0 4.8e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NIL PF09383.10 KNZ81648.1 - 0.018 14.8 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 NIL domain Connexin40_C PF16791.5 KNZ81648.1 - 0.33 12.3 3.1 0.7 11.2 3.1 1.5 1 0 0 1 1 1 0 Connexin 40 C-terminal domain Amidase PF01425.21 KNZ81649.1 - 3e-89 300.0 0.0 3.6e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Amidase IBN_N PF03810.19 KNZ81652.1 - 5.7e-10 39.0 0.0 1.1e-08 34.9 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KNZ81652.1 - 4.5e-05 23.5 0.1 0.00024 21.2 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein RIX1 PF08167.12 KNZ81652.1 - 6.1e-05 22.8 2.8 0.0011 18.8 0.6 3.5 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 KNZ81652.1 - 0.0024 16.5 0.3 0.057 12.0 0.1 2.5 2 0 0 2 2 2 1 Adaptin N terminal region CAS_CSE1 PF03378.15 KNZ81652.1 - 0.007 14.9 0.0 0.23 9.9 0.0 2.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus ParcG PF10274.9 KNZ81652.1 - 0.033 14.3 0.0 4.5 7.3 0.0 2.9 2 0 0 2 2 2 0 Parkin co-regulated protein DUF3385 PF11865.8 KNZ81652.1 - 0.043 13.7 0.1 12 5.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Cnd1 PF12717.7 KNZ81652.1 - 0.045 13.8 0.1 0.59 10.2 0.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KNZ81652.1 - 0.3 11.5 7.7 0.56 10.6 0.0 5.1 6 0 0 6 6 6 0 HEAT repeat RT_RNaseH PF17917.1 KNZ81653.1 - 1.5e-08 34.8 0.0 4.4e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ81653.1 - 6.5e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Ribosomal_S15 PF00312.22 KNZ81654.1 - 2e-14 53.6 0.8 4.3e-14 52.5 0.8 1.6 1 1 0 1 1 1 1 Ribosomal protein S15 NGP1NT PF08153.12 KNZ81655.1 - 2.6e-50 170.0 0.5 5.2e-50 169.0 0.0 1.7 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KNZ81655.1 - 5.6e-18 65.1 0.0 8.2e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KNZ81655.1 - 9.5e-05 22.0 0.3 0.00033 20.2 0.1 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KNZ81655.1 - 0.00019 21.4 0.0 0.00057 19.8 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 KNZ81655.1 - 0.0002 21.0 0.0 0.022 14.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KNZ81655.1 - 0.015 15.4 0.7 2.9 7.9 0.1 3.5 2 1 1 3 3 3 0 Dynamin family Arf PF00025.21 KNZ81655.1 - 0.02 14.4 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 KNZ81655.1 - 0.026 14.7 0.0 7.4 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RRP7 PF12923.7 KNZ81655.1 - 0.032 14.4 1.2 0.032 14.4 1.2 2.0 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Enolase_C PF00113.22 KNZ81656.1 - 1.2e-146 487.6 0.1 1.6e-146 487.2 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KNZ81656.1 - 1.6e-54 183.6 0.0 2.7e-54 182.8 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KNZ81656.1 - 2.5e-08 33.8 0.0 3.8e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KNZ81656.1 - 0.00036 19.8 0.4 0.00076 18.7 0.2 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus RabGAP-TBC PF00566.18 KNZ81658.1 - 3.6e-46 157.5 0.0 4.7e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain rve PF00665.26 KNZ81660.1 - 1e-07 32.1 0.0 1.1e-07 32.0 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain MMS22L_N PF14910.6 KNZ81660.1 - 0.026 13.0 0.1 0.027 13.0 0.1 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Rotamase PF00639.21 KNZ81662.1 - 5.6e-23 81.7 0.0 7.8e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KNZ81662.1 - 1.3e-18 67.6 0.0 1.9e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 KNZ81662.1 - 5.4e-07 29.6 0.3 2.4e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 KNZ81662.1 - 0.00062 20.6 0.0 0.00085 20.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 KNZ81662.1 - 0.17 12.6 0.0 0.27 12.0 0.0 1.3 1 0 0 1 1 1 0 X8 domain KNOX2 PF03791.13 KNZ81662.1 - 0.24 10.9 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 KNOX2 domain MOSC PF03473.17 KNZ81663.1 - 1.1e-20 74.0 0.0 1.5e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KNZ81663.1 - 1.1e-15 57.6 0.0 3.2e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain UCH PF00443.29 KNZ81664.1 - 1.7e-50 171.9 0.0 2.7e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KNZ81664.1 - 2e-25 90.0 0.4 2.9e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UvrC_HhH_N PF08459.11 KNZ81664.1 - 0.056 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal DUF3915 PF13054.6 KNZ81664.1 - 0.59 10.1 13.7 0.36 10.8 6.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3915) DUF5427 PF10310.9 KNZ81664.1 - 1.2 8.0 3.8 3.2 6.6 3.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Urm1 PF09138.11 KNZ81665.1 - 1e-37 128.4 0.1 1.1e-37 128.2 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 KNZ81665.1 - 0.00014 22.4 0.1 0.00016 22.2 0.1 1.2 1 0 0 1 1 1 1 ThiS family ADH_zinc_N PF00107.26 KNZ81666.1 - 1.9e-24 86.1 0.0 3.2e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ81666.1 - 1.2e-16 61.9 0.0 2.5e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KNZ81666.1 - 1.9e-06 27.7 0.0 1e-05 25.3 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PA PF02225.22 KNZ81666.1 - 0.018 15.0 0.1 0.048 13.7 0.1 1.8 1 0 0 1 1 1 0 PA domain Y_phosphatase PF00102.27 KNZ81667.1 - 1.6e-41 142.4 0.0 6.8e-27 94.5 0.0 3.0 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 KNZ81667.1 - 0.0015 18.7 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KNZ81667.1 - 0.0026 17.8 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 KNZ81667.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Exo84_C PF16528.5 KNZ81668.1 - 2.2e-22 79.9 6.7 2.6e-21 76.4 2.0 3.1 2 1 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KNZ81668.1 - 3e-15 56.1 2.3 3e-15 56.1 2.3 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KNZ81668.1 - 2.9e-09 37.1 0.6 7.1e-09 35.9 0.6 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec3-PIP2_bind PF15277.6 KNZ81668.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.6 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_13 PF16652.5 KNZ81668.1 - 0.079 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain efThoc1 PF11957.8 KNZ81669.1 - 2.5e-90 303.5 1.0 5e-85 286.0 0.1 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor GDP_Man_Dehyd PF16363.5 KNZ81669.1 - 6.7e-31 107.9 0.0 3.8e-29 102.1 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KNZ81669.1 - 3e-27 95.7 0.0 5.9e-25 88.1 0.0 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KNZ81669.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 KNZ81669.1 - 0.015 14.5 0.0 0.037 13.1 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain DUF3375 PF11855.8 KNZ81669.1 - 0.031 13.2 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) 3Beta_HSD PF01073.19 KNZ81669.1 - 0.095 11.7 0.0 0.45 9.5 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F5_F8_type_C PF00754.25 KNZ81670.1 - 0.019 15.1 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 F5/8 type C domain ANAPC10 PF03256.16 KNZ81670.1 - 0.033 13.8 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Laminin_N PF00055.17 KNZ81670.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Laminin N-terminal (Domain VI) UCH PF00443.29 KNZ81671.1 - 3.9e-41 141.3 0.0 9e-41 140.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 KNZ81671.1 - 4.3e-24 84.2 0.0 5.2e-20 71.1 0.1 2.7 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 KNZ81671.1 - 1e-08 35.2 0.2 0.00049 19.8 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase APG6_N PF17675.1 KNZ81671.1 - 0.04 14.5 0.7 0.11 13.1 0.7 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3695 PF12494.8 KNZ81671.1 - 0.081 12.8 0.3 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) DNA_methylase PF00145.17 KNZ81672.1 - 1.7e-37 129.6 0.0 6.9e-37 127.5 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 KNZ81672.1 - 5e-15 55.8 0.2 9.5e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 KNZ81672.1 - 2.3e-13 50.0 0.4 2.2e-06 27.5 0.1 3.2 2 1 1 3 3 3 2 BAH domain NAD_binding_1 PF00175.21 KNZ81673.1 - 3.8e-25 88.6 0.0 5.7e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KNZ81673.1 - 1e-19 70.7 0.0 1.9e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KNZ81673.1 - 4.3e-06 26.9 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KNZ81673.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.9 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain Phage_TAC_6 PF09550.10 KNZ81673.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC Pkinase PF00069.25 KNZ81674.1 - 5.3e-58 196.5 0.0 6.5e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81674.1 - 1.6e-25 89.9 0.0 2e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ81674.1 - 1.6e-05 24.0 0.1 2.2e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KNZ81674.1 - 0.00052 20.0 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ81674.1 - 0.029 13.7 0.2 0.058 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KNZ81674.1 - 0.043 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 KNZ81674.1 - 0.053 12.5 0.4 0.075 12.0 0.4 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 KNZ81674.1 - 0.063 12.6 0.0 0.29 10.4 0.0 1.8 1 1 0 2 2 2 0 Kinase-like Hemerythrin PF01814.23 KNZ81675.1 - 3.9e-05 24.3 2.0 0.00032 21.3 1.0 2.0 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF3474 PF11960.8 KNZ81675.1 - 0.0064 16.7 0.6 0.011 16.0 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3474) DUF3095 PF11294.8 KNZ81675.1 - 0.024 13.7 0.0 0.027 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) zf-C2H2_4 PF13894.6 KNZ81677.1 - 3.9e-11 42.8 38.8 0.25 12.3 0.1 7.7 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 KNZ81677.1 - 3.7e-10 39.7 41.9 0.072 13.6 0.3 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-met PF12874.7 KNZ81677.1 - 2.1e-09 37.4 38.2 0.041 14.3 0.8 7.1 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KNZ81677.1 - 6.7e-05 23.1 40.1 0.11 12.8 2.2 6.6 7 0 0 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KNZ81677.1 - 0.00018 21.8 26.1 0.092 13.1 8.8 4.1 2 2 2 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 KNZ81677.1 - 0.2 11.5 17.9 2.1 8.3 0.3 5.0 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 KNZ81677.1 - 0.27 11.7 0.1 0.27 11.7 0.1 6.6 7 0 0 7 7 7 0 Zinc-finger double domain CK_II_beta PF01214.18 KNZ81677.1 - 6.2 6.6 9.4 1.2 9.0 0.4 2.8 2 1 1 3 3 3 0 Casein kinase II regulatory subunit SCHIP-1 PF10148.9 KNZ81678.1 - 0.027 14.1 0.7 0.045 13.4 0.7 1.3 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 F-box-like PF12937.7 KNZ81679.1 - 2.8e-05 23.9 0.1 0.00017 21.4 0.0 2.4 2 1 0 2 2 2 1 F-box-like Retrotran_gag_2 PF14223.6 KNZ81680.1 - 2.6e-08 33.6 0.2 3.9e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.23 KNZ81680.1 - 0.23 11.6 0.9 0.44 10.7 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Sel1 PF08238.12 KNZ81681.1 - 3.1e-36 123.0 16.6 3.5e-08 33.9 0.1 5.9 6 0 0 6 6 6 5 Sel1 repeat HNH_repeat PF18780.1 KNZ81681.1 - 0.17 11.7 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 Homing endonuclease repeat SDH_C PF18317.1 KNZ81682.1 - 0.12 12.2 0.2 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain DNA_pol_A_exo1 PF01612.20 KNZ81683.1 - 8.6e-06 25.6 0.1 0.00033 20.4 0.2 2.4 1 1 1 2 2 2 2 3'-5' exonuclease zf-4CXXC_R1 PF10497.9 KNZ81684.1 - 0.038 14.2 0.1 0.048 13.9 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Abi_C PF14355.6 KNZ81685.1 - 0.12 12.5 1.3 0.22 11.7 0.1 2.0 2 0 0 2 2 2 0 Abortive infection C-terminus YdaS_antitoxin PF15943.5 KNZ81685.1 - 0.15 12.0 0.1 0.39 10.6 0.1 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF416 PF04222.12 KNZ81685.1 - 0.29 10.5 2.5 0.55 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Sld5 PF05916.11 KNZ81686.1 - 0.00019 21.9 0.0 0.00032 21.1 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 KNZ81686.1 - 0.02 15.0 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus NurA PF09376.10 KNZ81686.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 NurA domain PPR PF01535.20 KNZ81687.1 - 0.0041 17.3 0.2 14 6.2 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 KNZ81687.1 - 0.26 11.0 0.7 31 4.4 0.0 3.4 4 0 0 4 4 4 0 PPR repeat TPR_14 PF13428.6 KNZ81687.1 - 1 10.4 3.2 9.7 7.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Laminin_II PF06009.12 KNZ81688.1 - 0.079 13.0 6.0 0.27 11.3 4.9 2.4 2 1 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 KNZ81688.1 - 0.2 12.1 5.1 0.38 11.2 2.4 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 KNZ81688.1 - 0.21 12.2 6.3 0.21 12.2 1.2 2.6 2 1 0 2 2 2 0 Initiation control protein YabA tRNA-synt_1e PF01406.19 KNZ81688.1 - 0.22 10.8 0.9 0.49 9.7 0.9 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GrpE PF01025.19 KNZ81688.1 - 0.39 10.4 7.3 0.055 13.1 0.7 2.6 3 0 0 3 3 3 0 GrpE COG2 PF06148.11 KNZ81688.1 - 1.3 9.1 9.7 3.1 7.9 4.4 2.4 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YscO PF07321.12 KNZ81688.1 - 1.5 8.8 12.8 5 7.1 10.1 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO Spc7 PF08317.11 KNZ81688.1 - 4.2 6.1 11.4 8.2 5.2 11.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein ZapB PF06005.12 KNZ81688.1 - 4.3 7.8 13.8 0.69 10.4 5.4 2.9 3 0 0 3 3 3 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 KNZ81688.1 - 5.3 7.3 12.6 3.2 8.0 4.0 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ribo_biogen_C PF04034.13 KNZ81689.1 - 3.8e-51 172.1 0.0 5.2e-51 171.7 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KNZ81689.1 - 2e-14 53.1 0.1 3.4e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI PfkB PF00294.24 KNZ81690.1 - 2.9e-21 76.0 0.0 8.5e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase SeqA_N PF17206.3 KNZ81690.1 - 0.002 17.4 0.1 0.0065 15.8 0.1 1.8 2 0 0 2 2 2 1 SeqA protein N-terminal domain Ribosomal_L16 PF00252.18 KNZ81691.1 - 4.7e-46 156.1 0.0 5.8e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Kinesin PF00225.23 KNZ81692.1 - 6.3e-93 311.3 0.2 1.1e-92 310.6 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KNZ81692.1 - 2.1e-20 73.2 0.0 3.4e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding TPR_2 PF07719.17 KNZ81692.1 - 0.0032 17.4 0.1 0.0062 16.6 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ81692.1 - 0.0073 16.3 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ81692.1 - 0.0076 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ81692.1 - 0.033 15.0 0.1 0.11 13.4 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ81692.1 - 0.035 14.3 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ81692.1 - 0.055 14.1 0.2 0.11 13.1 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pex14_N PF04695.13 KNZ81692.1 - 9.9 6.8 12.1 0.73 10.5 3.9 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cytochrom_B561 PF03188.16 KNZ81693.1 - 1.3e-12 48.0 11.7 1.8e-12 47.5 11.7 1.2 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 KNZ81693.1 - 0.32 11.1 11.3 19 5.4 9.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF2427 PF10348.9 KNZ81693.1 - 1.2 8.9 13.0 0.032 14.0 3.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DUF1471 PF07338.13 KNZ81694.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1471) Med25 PF11232.8 KNZ81694.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Mce4_CUP1 PF11887.8 KNZ81695.1 - 0.26 10.7 7.0 0.79 9.1 7.0 1.9 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative ERM PF00769.19 KNZ81695.1 - 0.89 9.3 90.9 0.37 10.6 23.6 5.6 2 1 2 5 5 5 0 Ezrin/radixin/moesin family Synaptobrevin PF00957.21 KNZ81695.1 - 0.94 9.3 7.1 0.18 11.7 0.6 3.2 3 0 0 3 3 3 0 Synaptobrevin Pkinase PF00069.25 KNZ81696.1 - 2.1e-74 250.2 0.0 3.1e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81696.1 - 3.6e-44 151.0 0.0 6.1e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 KNZ81696.1 - 3.5e-38 129.6 0.5 7e-20 71.0 0.2 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 KNZ81696.1 - 5.8e-08 32.4 0.4 3.5e-07 29.8 0.0 2.3 3 0 0 3 3 3 1 Kinase-like DUF4520 PF15016.6 KNZ81696.1 - 0.0085 16.2 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4520) Haspin_kinase PF12330.8 KNZ81696.1 - 0.0086 15.1 0.1 0.024 13.6 0.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KNZ81696.1 - 0.095 12.6 3.6 0.31 10.9 0.6 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Melibiase_2 PF16499.5 KNZ81697.1 - 3.4e-56 190.5 1.5 6.2e-56 189.6 1.5 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KNZ81697.1 - 8.6e-16 57.8 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain WD40 PF00400.32 KNZ81698.1 - 1.2e-55 184.2 20.4 3.8e-08 33.9 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KNZ81698.1 - 2.1e-26 92.0 2.5 3.4e-26 91.3 2.5 1.3 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KNZ81698.1 - 1.2e-20 73.6 1.0 0.00017 21.8 0.0 6.4 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ81698.1 - 3.7e-12 46.2 0.1 0.0022 17.4 0.0 5.1 5 1 1 6 6 6 3 WD40-like domain Ge1_WD40 PF16529.5 KNZ81698.1 - 2.1e-07 30.2 0.6 1.1 8.2 0.0 5.6 2 2 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KNZ81698.1 - 4.7e-05 23.4 0.0 3.1 7.6 0.0 3.5 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KNZ81698.1 - 0.0005 18.7 0.8 0.0038 15.8 0.3 2.6 2 1 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 KNZ81698.1 - 0.00065 19.6 1.6 13 5.8 0.0 6.0 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat HALZ PF02183.18 KNZ81698.1 - 0.0013 18.9 0.9 0.066 13.4 0.1 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper Nup160 PF11715.8 KNZ81698.1 - 0.0013 17.5 0.2 0.13 10.9 0.1 3.6 1 1 3 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 KNZ81698.1 - 0.0046 16.3 0.2 14 4.9 0.0 3.6 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Golgin_A5 PF09787.9 KNZ81698.1 - 0.02 14.4 0.2 0.02 14.4 0.2 1.9 2 0 0 2 2 1 0 Golgin subfamily A member 5 BicD PF09730.9 KNZ81698.1 - 0.036 12.5 0.1 0.069 11.6 0.1 1.4 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D APG6_N PF17675.1 KNZ81698.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Nucleoporin_N PF08801.11 KNZ81698.1 - 0.23 10.2 0.5 11 4.6 0.1 3.2 2 2 2 4 4 4 0 Nup133 N terminal like adh_short_C2 PF13561.6 KNZ81699.1 - 1.8e-54 184.8 0.0 2.6e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ81699.1 - 5.7e-44 149.9 0.1 8.4e-44 149.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ81699.1 - 3.5e-11 43.3 0.2 5.9e-11 42.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ81699.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FtsK_alpha PF17854.1 KNZ81699.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK alpha domain CotJB PF12652.7 KNZ81701.1 - 0.032 14.4 0.1 0.55 10.5 0.0 2.3 2 0 0 2 2 2 0 CotJB protein MSA-2c PF12238.8 KNZ81701.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 KNZ81702.1 - 2e-21 76.3 38.3 9.7e-16 57.6 11.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkr1 PF08636.10 KNZ81702.1 - 0.15 12.3 5.0 41 4.4 0.0 3.8 3 0 0 3 3 3 0 ER protein Pkr1 6PF2K PF01591.18 KNZ81703.1 - 1.1e-54 185.0 0.0 1.8e-54 184.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KNZ81703.1 - 6.2e-22 78.2 0.0 4.6e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KNZ81703.1 - 2.4e-06 27.8 0.0 1.1e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 KNZ81703.1 - 0.002 17.6 0.0 0.0043 16.5 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Toprim_3 PF13362.6 KNZ81703.1 - 0.041 14.3 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Toprim domain tRNA_lig_kinase PF08303.11 KNZ81703.1 - 0.12 12.5 0.4 0.39 10.8 0.0 2.0 3 0 0 3 3 3 0 tRNA ligase kinase domain IGR PF09597.10 KNZ81703.1 - 0.16 12.1 0.1 0.97 9.6 0.0 2.2 2 0 0 2 2 2 0 IGR protein motif AAA PF00004.29 KNZ81703.1 - 0.16 12.4 0.1 5.8 7.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KNZ81703.1 - 0.18 11.7 1.0 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase FoP_duplication PF13865.6 KNZ81704.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 KNZ81704.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IFT20 PF14931.6 KNZ81705.1 - 0.016 15.4 0.1 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 McrBC PF10117.9 KNZ81705.1 - 0.07 12.2 0.1 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component TPT PF03151.16 KNZ81706.1 - 1.6e-11 44.1 9.9 2e-11 43.8 9.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF1118 PF06549.12 KNZ81706.1 - 3.6 7.9 7.9 0.29 11.5 2.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1118) LSM PF01423.22 KNZ81707.1 - 6.7e-15 54.5 0.0 8.1e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain RVP_2 PF08284.11 KNZ81708.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Retroviral aspartyl protease GUN4_N PF16416.5 KNZ81708.1 - 0.14 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal adh_short PF00106.25 KNZ81710.1 - 4.7e-37 127.3 0.0 6.3e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ81710.1 - 1.8e-24 86.6 0.0 2.5e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ81710.1 - 7.2e-06 26.0 0.0 1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KNZ81710.1 - 1.5e-05 24.6 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KNZ81710.1 - 2.9e-05 23.6 0.0 3.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 KNZ81710.1 - 0.0038 16.4 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KNZ81710.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KNZ81710.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family BCDHK_Adom3 PF10436.9 KNZ81711.1 - 1.6e-67 226.4 0.0 4.1e-67 225.1 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KNZ81711.1 - 1.2e-12 48.4 0.0 2.4e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KNZ81711.1 - 0.0041 16.9 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.14 KNZ81712.1 - 1.9e-28 99.6 0.0 2.5e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KNZ81712.1 - 9.4e-12 45.3 0.1 1.5e-10 41.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ81712.1 - 6.7e-05 22.3 0.0 0.00012 21.5 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KNZ81712.1 - 0.00021 21.3 0.6 0.034 14.1 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 KNZ81712.1 - 0.00083 19.8 0.0 1 9.9 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 KNZ81712.1 - 0.012 14.8 0.0 1.2 8.2 0.0 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) PGAP1 PF07819.13 KNZ81712.1 - 0.013 15.2 0.3 0.023 14.4 0.3 1.3 1 0 0 1 1 1 0 PGAP1-like protein PRMT5 PF05185.16 KNZ81712.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DAO PF01266.24 KNZ81712.1 - 0.23 11.0 6.4 1.2 8.6 0.1 3.0 1 1 1 3 3 3 0 FAD dependent oxidoreductase PITH PF06201.13 KNZ81713.1 - 4.2e-37 127.7 0.0 5.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.15 KNZ81714.1 - 3.9e-20 71.1 0.0 9.4e-20 69.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KNZ81714.1 - 4.5e-17 61.8 0.6 8.6e-17 60.9 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Pkinase PF00069.25 KNZ81715.1 - 3e-46 157.9 0.0 4.1e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81715.1 - 4e-24 85.3 0.0 5.4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KNZ81715.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KNZ81715.1 - 0.01 15.8 0.1 0.018 15.0 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 KNZ81715.1 - 0.013 14.5 0.1 0.013 14.5 0.1 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase MR_MLE_C PF13378.6 KNZ81719.1 - 3.8e-46 157.4 0.8 4.7e-45 153.8 0.8 2.0 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KNZ81719.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 KNZ81719.1 - 0.008 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Peptidase_C25_C PF03785.14 KNZ81719.1 - 0.013 15.4 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain Herpes_Helicase PF02689.14 KNZ81721.1 - 3.3e-05 22.1 0.0 3.4e-05 22.0 0.0 1.0 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.6 KNZ81721.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Velvet PF11754.8 KNZ81723.1 - 8.3e-62 209.4 0.2 1.4e-39 136.6 0.0 2.4 2 1 1 3 3 3 2 Velvet factor HNH_2 PF13391.6 KNZ81723.1 - 2.8e-07 30.6 0.1 5.4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease NAD_binding_10 PF13460.6 KNZ81724.1 - 5.9e-24 85.0 0.0 7.5e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding EF1G PF00647.19 KNZ81725.1 - 2.3e-17 63.0 0.2 2.6e-13 50.0 0.0 2.4 1 1 1 2 2 2 2 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 KNZ81725.1 - 4.9e-10 39.6 0.0 1e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KNZ81725.1 - 1.4e-09 38.0 0.3 5.4e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KNZ81725.1 - 1.7e-07 31.2 0.0 4.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KNZ81725.1 - 7.4e-06 26.3 0.0 2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KNZ81725.1 - 1.8e-05 24.8 0.0 8.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KNZ81725.1 - 0.015 15.6 0.0 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KNZ81725.1 - 0.04 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF202 PF02656.15 KNZ81726.1 - 0.083 13.3 1.0 7.6 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Gram_pos_anchor PF00746.21 KNZ81726.1 - 8.8 6.4 8.4 0.13 12.2 0.6 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif GPI-anchored PF10342.9 KNZ81727.1 - 2.1e-05 25.2 0.2 5.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AA_permease_2 PF13520.6 KNZ81728.1 - 2.6e-35 122.1 47.4 3.2e-35 121.8 47.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ81728.1 - 3.1e-15 55.7 43.0 5e-15 55.1 43.0 1.2 1 0 0 1 1 1 1 Amino acid permease CHASE6_C PF17150.4 KNZ81728.1 - 0.22 12.2 0.1 0.4 11.4 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain DUF2383 PF09537.10 KNZ81729.1 - 0.096 13.0 0.3 0.23 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) RNase_H PF00075.24 KNZ81730.1 - 2.6e-09 37.4 0.3 1.4e-08 35.1 0.0 2.2 2 0 0 2 2 2 1 RNase H Exo_endo_phos_2 PF14529.6 KNZ81731.1 - 9.4e-20 70.6 0.3 2.5e-19 69.3 0.3 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 KNZ81731.1 - 2.5e-05 23.9 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Spore_III_AB PF09548.10 KNZ81731.1 - 0.14 12.2 2.6 0.3 11.2 1.1 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AA_permease_2 PF13520.6 KNZ81732.1 - 2e-36 125.7 55.4 2.7e-36 125.3 55.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KNZ81732.1 - 3.4e-16 58.9 47.4 4.8e-16 58.4 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease PIF1 PF05970.14 KNZ81733.1 - 1.1e-30 107.0 0.0 1.2e-30 106.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ81733.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal PIF1 PF05970.14 KNZ81734.1 - 3.7e-18 65.9 0.1 4.1e-18 65.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ81734.1 - 0.035 13.8 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KNZ81734.1 - 0.1 12.9 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Helitron_like_N PF14214.6 KNZ81735.1 - 6.5e-11 42.8 0.2 8.4e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Y1_Tnp PF01797.16 KNZ81738.1 - 0.32 11.1 7.2 1.7 8.8 0.7 2.7 1 1 0 2 2 2 0 Transposase IS200 like DUF4304 PF14137.6 KNZ81738.1 - 6.3 7.0 8.1 0.76 9.9 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) Alanine_zipper PF11839.8 KNZ81739.1 - 0.2 12.1 10.9 0.31 11.4 10.9 1.2 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein PIF1 PF05970.14 KNZ81741.1 - 6.5e-24 84.8 0.0 7.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase CBP4 PF07960.11 KNZ81743.1 - 0.0015 18.4 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 CBP4 FIBP PF05427.11 KNZ81743.1 - 0.041 13.2 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) TauD PF02668.16 KNZ81744.1 - 9.5e-60 202.7 0.3 1.2e-59 202.3 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATA PF00320.27 KNZ81745.1 - 3.6e-15 55.3 4.1 6.8e-15 54.4 4.1 1.5 1 0 0 1 1 1 1 GATA zinc finger MAJIN PF15077.6 KNZ81745.1 - 0.062 13.1 2.8 0.19 11.5 2.8 1.8 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1295 PF06966.12 KNZ81747.1 - 4e-12 46.2 0.0 4.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KNZ81747.1 - 1.8e-10 40.2 0.5 2.6e-10 39.7 0.5 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Steroid_dh PF02544.16 KNZ81747.1 - 3e-07 30.6 0.0 3.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Med22 PF06179.12 KNZ81748.1 - 3.5e-19 69.0 2.5 4.7e-19 68.5 2.5 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.12 KNZ81748.1 - 0.098 13.4 5.3 3.9 8.2 2.1 2.2 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF1664 PF07889.12 KNZ81749.1 - 0.025 14.6 1.0 2.4 8.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 KNZ81749.1 - 0.049 13.2 1.5 0.075 12.6 1.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Lebercilin PF15619.6 KNZ81749.1 - 2.1 8.0 9.0 7.6 6.1 0.0 2.8 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease CENP-F_leu_zip PF10473.9 KNZ81749.1 - 2.8 8.0 8.9 0.29 11.2 3.7 2.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 OPT PF03169.15 KNZ81750.1 - 9.5e-132 440.7 23.0 1.1e-131 440.5 23.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2721 PF11026.8 KNZ81750.1 - 3.7 7.5 9.7 9 6.2 4.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Actin PF00022.19 KNZ81752.1 - 5.9e-36 123.9 0.0 1.1e-30 106.6 0.0 2.8 2 1 0 2 2 2 2 Actin DUF3669 PF12417.8 KNZ81753.1 - 1.3e-06 28.5 0.1 2.8e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 Zinc finger protein Mito_carr PF00153.27 KNZ81754.1 - 2.8e-43 145.7 3.1 1.8e-24 85.5 0.6 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein Methyltransf_16 PF10294.9 KNZ81755.1 - 2.4e-16 60.0 0.0 4.1e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 KNZ81755.1 - 0.22 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mitofilin PF09731.9 KNZ81757.1 - 1.5e-114 384.1 14.7 4.2e-114 382.7 14.7 1.6 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Peptidase_M49 PF03571.15 KNZ81757.1 - 0.074 11.4 1.0 0.12 10.7 1.0 1.2 1 0 0 1 1 1 0 Peptidase family M49 MnmE_helical PF12631.7 KNZ81757.1 - 0.17 12.1 9.4 0.056 13.6 5.1 2.3 3 0 0 3 3 3 0 MnmE helical domain GBP_C PF02841.14 KNZ81757.1 - 0.96 8.8 11.2 1.8 7.9 11.2 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF2894 PF11445.8 KNZ81757.1 - 2.7 8.4 9.7 1.3 9.4 4.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2894) SbsC_C PF18058.1 KNZ81757.1 - 7 6.9 7.8 6.4 7.0 3.8 2.4 2 0 0 2 2 2 0 SbsC C-terminal domain USP8_interact PF08941.10 KNZ81758.1 - 0.011 15.6 0.1 0.031 14.1 0.0 1.7 2 0 0 2 2 2 0 USP8 interacting Nucleoporin_FG PF13634.6 KNZ81759.1 - 1.3e-38 131.7 177.9 3.1e-11 43.9 31.8 4.6 2 1 4 6 6 6 5 Nucleoporin FG repeat region NTP_transf_9 PF04248.12 KNZ81759.1 - 7.1e-35 118.8 0.1 6e-27 93.4 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF427) YlqD PF11068.8 KNZ81759.1 - 9.1 6.7 7.3 7.8 6.9 0.1 2.5 2 1 0 2 2 2 0 YlqD protein DUF202 PF02656.15 KNZ81767.1 - 8e-14 51.8 4.4 8e-14 51.8 4.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.6 KNZ81767.1 - 0.0089 15.7 0.7 0.013 15.2 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF4401 PF14351.6 KNZ81767.1 - 0.011 15.1 1.5 0.015 14.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DnaJ_C PF01556.18 KNZ81768.1 - 1.9e-26 92.9 0.1 2.4e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KNZ81768.1 - 1.5e-05 25.0 0.1 2.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain RCC1 PF00415.18 KNZ81769.1 - 1.5e-17 63.9 0.7 0.0014 19.2 0.0 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KNZ81769.1 - 2.2e-16 60.1 0.1 6.7e-07 29.5 0.0 3.0 2 1 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 KNZ81769.1 - 6.1e-08 32.3 0.0 6.1e-08 32.3 0.0 5.5 7 0 0 7 7 7 1 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 KNZ81769.1 - 5.7e-07 30.0 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ81769.1 - 6.4e-07 29.2 0.4 0.013 15.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 KNZ81769.1 - 7.3e-06 26.4 0.7 9e-05 23.0 0.4 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ81769.1 - 0.0028 17.9 1.7 0.23 11.8 0.4 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 KNZ81769.1 - 0.0066 16.8 1.9 0.79 10.3 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat E2F_TDP PF02319.20 KNZ81769.1 - 0.1 12.6 0.0 15 5.7 0.0 3.0 3 0 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain EKLF_TAD1 PF16832.5 KNZ81769.1 - 0.27 11.1 0.8 0.63 9.9 0.8 1.5 1 0 0 1 1 1 0 Erythroid krueppel-like transcription factor, transactivation 1 eIF3_subunit PF08597.10 KNZ81770.1 - 6.1e-61 206.4 21.3 6.8e-61 206.2 21.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.8 KNZ81770.1 - 0.098 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) COQ9 PF08511.11 KNZ81771.1 - 9e-10 38.2 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 COQ9 Aa_trans PF01490.18 KNZ81773.1 - 2e-24 86.1 22.6 3.6e-24 85.2 22.6 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-C2H2_4 PF13894.6 KNZ81774.1 - 0.036 14.9 0.2 0.11 13.4 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Glyco_hydro_cc PF11790.8 KNZ81775.1 - 2.9e-45 154.7 0.1 3.9e-45 154.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Herpes_pp85 PF04637.12 KNZ81775.1 - 4.1 5.7 5.3 6.1 5.1 5.3 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Complex1_LYR PF05347.15 KNZ81776.1 - 2.2e-08 34.0 0.3 2.2e-08 34.0 0.3 2.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KNZ81776.1 - 0.012 16.4 2.3 0.012 16.4 2.3 2.8 2 2 1 3 3 3 0 Complex1_LYR-like ERG4_ERG24 PF01222.17 KNZ81777.1 - 7e-125 417.2 20.8 1.9e-122 409.2 20.8 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KNZ81777.1 - 1.7e-06 27.7 0.4 1.7e-06 27.7 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 KNZ81777.1 - 1.8e-05 25.1 0.1 1.8e-05 25.1 0.1 3.2 4 1 0 4 4 4 1 Phospholipid methyltransferase ICMT PF04140.14 KNZ81777.1 - 3.7e-05 24.0 0.1 0.00058 20.2 0.0 2.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Methyltr_RsmB-F PF01189.17 KNZ81778.1 - 0.045 13.4 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF4515 PF14988.6 KNZ81778.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Citrate_synt PF00285.21 KNZ81779.1 - 3.1e-120 401.6 0.0 3.7e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Pap_E4 PF02711.14 KNZ81780.1 - 0.097 13.6 4.5 0.78 10.7 4.2 2.2 2 0 0 2 2 2 0 E4 protein MGC-24 PF05283.11 KNZ81780.1 - 1.1 9.7 10.4 1.8 9.0 10.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Hamartin PF04388.12 KNZ81780.1 - 4.7 5.7 8.2 6 5.4 8.2 1.0 1 0 0 1 1 1 0 Hamartin protein Pcc1 PF09341.10 KNZ81781.1 - 4.1e-23 81.3 3.4 4.9e-23 81.1 3.4 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 AAA-ATPase_like PF09820.9 KNZ81782.1 - 4.5e-43 147.7 0.0 7.7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AAA-ATPase PDDEXK_9 PF08011.11 KNZ81782.1 - 4.1e-08 33.1 0.0 7.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Lon_C PF05362.13 KNZ81783.1 - 6.7e-33 114.0 0.3 1.2e-32 113.1 0.1 1.5 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 KNZ81783.1 - 5.7e-20 72.1 0.0 9.5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KNZ81783.1 - 5.5e-09 36.1 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KNZ81783.1 - 0.00078 19.6 0.0 0.0034 17.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 KNZ81783.1 - 0.005 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KNZ81783.1 - 0.011 15.5 0.0 0.12 12.1 0.0 2.3 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KNZ81783.1 - 0.017 15.4 0.1 0.73 10.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 KNZ81783.1 - 0.018 14.3 0.1 0.034 13.3 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 KNZ81783.1 - 0.03 14.7 0.1 0.084 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain ClpB_D2-small PF10431.9 KNZ81783.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein PSD5 PF07637.11 KNZ81783.1 - 0.088 13.2 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) Parvo_NS1 PF01057.17 KNZ81783.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M24 PF00557.24 KNZ81784.1 - 1.5e-15 57.4 0.2 2e-15 57.0 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Methyltransf_25 PF13649.6 KNZ81786.1 - 9.8e-13 48.6 0.0 1.8e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ81786.1 - 2.4e-09 37.7 0.0 7.5e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KNZ81786.1 - 3.7e-07 29.7 0.0 6.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KNZ81786.1 - 6.5e-07 29.3 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ81786.1 - 5.7e-05 23.0 0.0 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ81786.1 - 0.0002 20.9 0.0 0.00061 19.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KNZ81786.1 - 0.00096 19.9 0.0 0.0033 18.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KNZ81786.1 - 0.0021 17.6 0.0 0.0066 15.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 KNZ81786.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KNZ81786.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase NDUF_B8 PF05821.11 KNZ81787.1 - 3.7e-05 23.7 0.0 5.8e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Mgr1 PF08602.10 KNZ81787.1 - 0.21 10.3 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit PH PF00169.29 KNZ81788.1 - 1.6e-05 25.4 0.0 0.00098 19.6 0.0 3.1 3 0 0 3 3 3 1 PH domain PH_9 PF15410.6 KNZ81788.1 - 0.0078 16.6 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RXT2_N PF08595.11 KNZ81788.1 - 0.041 13.9 9.2 0.14 12.2 9.2 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 KNZ81788.1 - 0.7 9.2 8.8 1.2 8.4 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 KNZ81788.1 - 2 9.0 7.4 8.6 7.0 7.4 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 KNZ81788.1 - 2.2 8.7 11.6 5.6 7.4 11.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain XPG_N PF00752.17 KNZ81789.1 - 7.4e-29 100.2 0.0 1.8e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KNZ81789.1 - 3.2e-27 94.7 0.0 1.4e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 KNZ81789.1 - 0.00082 18.9 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 KNZ81789.1 - 0.013 16.1 0.0 0.23 12.1 0.0 2.8 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold CtaG_Cox11 PF04442.14 KNZ81790.1 - 2.8e-61 206.0 0.0 3.6e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DnaJ PF00226.31 KNZ81791.1 - 2.1e-15 56.6 0.9 2.1e-15 56.6 0.9 1.9 2 0 0 2 2 2 1 DnaJ domain Jak1_Phl PF17887.1 KNZ81791.1 - 0.18 11.8 2.8 0.35 10.8 2.8 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain RMI1_N PF08585.12 KNZ81792.1 - 1.3e-37 129.7 0.0 2.2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 RecQ mediated genome instability protein Carn_acyltransf PF00755.20 KNZ81793.1 - 2.2e-157 525.2 0.0 2.5e-157 525.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_12 PF13087.6 KNZ81794.1 - 2.7e-34 118.6 0.0 6.3e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ81794.1 - 7.4e-22 78.4 3.1 3.7e-11 43.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KNZ81794.1 - 5.2e-14 52.4 0.0 1.4e-13 51.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ81794.1 - 6.7e-11 42.7 0.0 1.9e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ81794.1 - 0.00025 21.1 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KNZ81794.1 - 0.0007 19.5 0.0 0.0023 17.8 0.0 1.8 1 1 0 1 1 1 1 Helicase AAA_16 PF13191.6 KNZ81794.1 - 0.00082 19.8 0.0 0.0026 18.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 KNZ81794.1 - 0.00084 19.2 0.5 1.6 8.4 0.0 3.3 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KNZ81794.1 - 0.0021 17.4 0.5 0.24 10.6 0.1 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KNZ81794.1 - 0.015 14.7 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 KNZ81794.1 - 0.016 14.8 0.8 5.2 6.5 0.0 2.6 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KNZ81794.1 - 0.038 14.3 0.1 0.28 11.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KNZ81794.1 - 0.11 12.9 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 KNZ81795.1 - 1.9e-31 109.2 0.0 5.1e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ81795.1 - 2.5e-26 93.0 2.4 5.1e-14 52.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KNZ81795.1 - 9.3e-18 64.6 0.0 3.9e-17 62.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ81795.1 - 4.3e-12 46.6 0.8 1.6e-11 44.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KNZ81795.1 - 1.3e-05 25.6 0.0 3.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 KNZ81795.1 - 9.7e-05 22.4 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 KNZ81795.1 - 0.00024 21.0 0.2 0.0023 17.8 0.2 2.4 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 KNZ81795.1 - 0.0004 20.2 0.0 0.097 12.4 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 KNZ81795.1 - 0.0012 18.1 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KNZ81795.1 - 0.0016 18.7 0.2 0.011 16.0 0.2 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 KNZ81795.1 - 0.0025 17.3 0.2 0.019 14.4 0.0 2.3 3 0 0 3 3 3 1 PhoH-like protein AAA_25 PF13481.6 KNZ81795.1 - 0.003 17.2 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KNZ81795.1 - 0.003 18.0 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KNZ81795.1 - 0.01 15.1 0.5 0.022 14.0 0.0 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 KNZ81795.1 - 0.011 15.3 0.5 0.052 13.1 0.0 2.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 KNZ81795.1 - 0.02 15.4 0.5 0.054 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 KNZ81795.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 KNZ81795.1 - 0.021 14.6 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 KNZ81795.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DEAD PF00270.29 KNZ81795.1 - 0.023 14.5 0.1 0.073 12.8 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase Rad17 PF03215.15 KNZ81795.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain TIP49 PF06068.13 KNZ81795.1 - 0.064 12.4 1.0 0.24 10.5 0.0 2.3 3 0 0 3 3 3 0 TIP49 P-loop domain AAA_33 PF13671.6 KNZ81795.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KNZ81795.1 - 0.067 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 KNZ81795.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 KNZ81795.1 - 0.11 12.3 0.3 0.45 10.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 KNZ81795.1 - 0.12 12.2 0.2 0.85 9.5 0.1 2.4 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 KNZ81795.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SpoVT_C PF15714.5 KNZ81795.1 - 0.46 10.6 1.8 21 5.2 0.4 2.4 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Pam16 PF03656.13 KNZ81796.1 - 4.9e-06 26.6 0.0 6.2e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KNZ81796.1 - 0.003 17.6 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Methyltransf_31 PF13847.6 KNZ81797.1 - 8.5e-14 51.6 0.0 1.2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ81797.1 - 1.9e-08 35.0 0.0 3.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ81797.1 - 4.9e-08 33.6 0.0 3.1e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ81797.1 - 8.3e-06 26.4 0.0 2.1e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KNZ81797.1 - 3.8e-05 23.6 0.0 5.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ81797.1 - 0.009 15.6 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KNZ81797.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase MA3 PF02847.17 KNZ81798.1 - 8.2e-23 80.5 0.0 2.3e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 KNZ81798.1 - 1.5e-22 80.3 1.4 2.5e-22 79.5 1.4 1.4 1 0 0 1 1 1 1 MIF4G domain AAT PF03417.16 KNZ81798.1 - 0.016 14.9 0.1 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Pox_P35 PF03213.14 KNZ81798.1 - 0.033 13.4 0.0 0.089 12.0 0.0 1.8 1 0 0 1 1 1 0 Poxvirus P35 protein DUF4473 PF14747.6 KNZ81798.1 - 0.037 14.6 0.3 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Svf1_C PF17187.4 KNZ81799.1 - 5.6e-45 153.1 0.0 9.6e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KNZ81799.1 - 1.1e-42 145.9 0.1 1.6e-42 145.3 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain GMC_oxred_N PF00732.19 KNZ81800.1 - 2.4e-57 194.5 0.0 1.7e-46 159.0 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ81800.1 - 4.4e-35 121.3 0.0 7.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KNZ81800.1 - 3.7e-07 30.1 0.1 9.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KNZ81800.1 - 1.5e-06 27.6 0.1 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KNZ81800.1 - 5.6e-06 25.7 0.0 8.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KNZ81800.1 - 8e-05 22.8 0.2 0.00024 21.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KNZ81800.1 - 0.00044 19.6 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KNZ81800.1 - 0.0026 17.1 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KNZ81800.1 - 0.0059 15.9 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase LHC PF00556.20 KNZ81800.1 - 0.0074 16.5 0.7 0.016 15.4 0.7 1.5 1 0 0 1 1 1 1 Antenna complex alpha/beta subunit Pyr_redox PF00070.27 KNZ81800.1 - 0.019 15.5 0.1 0.24 12.0 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KNZ81800.1 - 0.13 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KNZ81800.1 - 0.13 12.2 0.1 0.4 10.7 0.1 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KNZ81800.1 - 0.15 10.7 0.2 0.3 9.7 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.6 KNZ81800.1 - 0.19 10.8 0.0 2.5 7.2 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KNZ81800.1 - 1.1 8.5 3.8 5.6 6.2 0.6 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase RhoGAP PF00620.27 KNZ81801.1 - 1e-35 122.8 0.0 1.7e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 KNZ81801.1 - 0.08 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Glyco_hydro_17 PF00332.18 KNZ81802.1 - 9.9e-12 45.1 4.9 4.3e-09 36.4 4.9 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF4330 PF14221.6 KNZ81802.1 - 0.0073 16.5 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4330) ODV-E18 PF10717.9 KNZ81802.1 - 0.96 9.4 4.2 0.91 9.4 0.7 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Drf_GBD PF06371.13 KNZ81803.1 - 2e-15 56.9 0.1 2e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain GMC_oxred_N PF00732.19 KNZ81804.1 - 1.9e-61 208.1 0.0 2.4e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KNZ81804.1 - 7.8e-27 94.6 0.0 2.1e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KNZ81804.1 - 2.8e-05 24.3 0.2 6.9e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KNZ81804.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KNZ81804.1 - 0.00016 20.9 0.1 0.0035 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KNZ81804.1 - 0.00059 19.5 0.2 0.0048 16.5 0.0 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ81804.1 - 0.0018 17.6 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KNZ81804.1 - 0.0027 17.0 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KNZ81804.1 - 0.014 14.7 0.0 0.26 10.5 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KNZ81804.1 - 0.033 12.9 0.0 0.055 12.2 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 KNZ81804.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Asp_protease_2 PF13650.6 KNZ81805.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.6 1 1 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.11 KNZ81805.1 - 0.11 12.3 0.1 0.28 10.9 0.1 1.7 1 1 1 2 2 2 0 Retroviral aspartyl protease Integrase_H2C2 PF17921.1 KNZ81806.1 - 4.4e-08 33.1 0.2 8.9e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Peptidase_S9_N PF02897.15 KNZ81806.1 - 0.046 12.5 0.0 0.063 12.1 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF4824 PF16106.5 KNZ81807.1 - 0.0028 17.0 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4824) DnaJ_C PF01556.18 KNZ81808.1 - 3.3e-20 72.7 0.0 5.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KNZ81808.1 - 4.9e-15 55.4 0.0 8.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Kelch_5 PF13854.6 KNZ81809.1 - 1.6e-11 43.9 0.0 5.8e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 KNZ81809.1 - 2.9e-10 39.7 0.0 0.00087 19.2 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 KNZ81809.1 - 1.3e-05 25.1 2.3 0.16 12.0 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 KNZ81809.1 - 0.00036 20.0 0.0 0.095 12.3 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 KNZ81809.1 - 0.0036 17.5 2.9 0.052 13.9 0.5 3.3 2 1 1 3 3 3 1 Kelch motif Rax2 PF12768.7 KNZ81809.1 - 0.004 16.6 0.0 0.0095 15.4 0.0 1.6 1 0 0 1 1 1 1 Cortical protein marker for cell polarity ACBP PF00887.19 KNZ81810.1 - 9.7e-28 96.2 0.9 1.5e-27 95.6 0.9 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein PH PF00169.29 KNZ81811.1 - 1.3e-34 118.9 1.8 2.6e-18 66.5 0.2 2.6 2 1 0 2 2 2 2 PH domain PH_11 PF15413.6 KNZ81811.1 - 6.4e-18 65.1 4.0 5.7e-07 29.9 3.8 3.3 2 1 1 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 KNZ81811.1 - 1.3e-07 31.8 1.1 1.4e-05 25.2 0.1 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 KNZ81811.1 - 0.00041 20.7 1.4 0.35 11.2 1.0 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 KNZ81811.1 - 0.00047 20.0 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 Pleckstrin homology domain PH_4 PF15404.6 KNZ81811.1 - 0.024 14.4 0.6 0.36 10.6 0.0 2.7 3 0 0 3 3 3 0 Pleckstrin homology domain PH_2 PF08458.10 KNZ81811.1 - 0.12 12.8 0.1 6.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Fungal_trans_2 PF11951.8 KNZ81812.1 - 1.1e-27 96.8 6.1 1.5e-27 96.4 6.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ81812.1 - 0.00034 20.7 6.9 0.00067 19.7 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KNZ81813.1 - 3.8e-37 128.0 0.1 5.7e-37 127.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ81813.1 - 0.00011 22.2 8.3 0.00021 21.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VTC PF09359.10 KNZ81814.1 - 7.1e-95 317.5 0.0 7.1e-95 317.5 0.0 2.7 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 KNZ81814.1 - 4.1e-11 43.4 19.8 9.5e-07 29.1 0.7 3.2 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 KNZ81814.1 - 3.3e-10 40.2 1.7 6.4e-10 39.3 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF1319 PF07028.11 KNZ81814.1 - 0.05 13.8 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Gtr1_RagA PF04670.12 KNZ81815.1 - 1.5e-51 175.0 0.1 2e-51 174.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 KNZ81815.1 - 0.00046 19.7 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KNZ81815.1 - 0.0005 20.1 0.0 0.00095 19.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 KNZ81815.1 - 0.0022 18.2 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 KNZ81815.1 - 0.026 14.6 0.1 0.075 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ81815.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 KNZ81815.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.22 KNZ81815.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Ras family DUF1729 PF08354.10 KNZ81816.1 - 3.2e-148 493.4 0.0 5.8e-148 492.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 KNZ81816.1 - 2.3e-73 246.2 0.0 4.9e-73 245.1 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KNZ81816.1 - 1.6e-72 243.1 0.0 1.4e-71 240.1 0.0 2.3 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain Acyl_transf_1 PF00698.21 KNZ81816.1 - 1.5e-70 238.2 0.0 5.2e-69 233.2 0.0 3.3 4 0 0 4 4 4 1 Acyl transferase domain SAT PF16073.5 KNZ81816.1 - 1.2e-34 120.2 0.2 4.9e-34 118.1 0.0 2.1 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 KNZ81816.1 - 2.3e-29 102.0 0.5 4.6e-29 101.0 0.5 1.5 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 KNZ81816.1 - 8.3e-26 90.0 0.1 3.2e-25 88.1 0.0 2.0 2 0 0 2 2 2 1 MaoC like domain ketoacyl-synt PF00109.26 KNZ81816.1 - 4.3e-25 88.8 0.4 9.9e-25 87.6 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAS_meander PF17951.1 KNZ81816.1 - 1.5e-23 83.2 0.0 3.9e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain Ketoacyl-synt_C PF02801.22 KNZ81816.1 - 1.4e-14 54.1 0.0 3.6e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 KNZ81816.1 - 2.3e-13 50.2 0.0 6.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 KNZ81816.1 - 4e-09 36.2 0.1 1.9e-07 30.8 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ81816.1 - 2.5e-05 24.0 0.0 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ81816.1 - 0.034 14.1 0.1 0.22 11.4 0.0 2.2 2 0 0 2 2 2 0 KR domain DEAD PF00270.29 KNZ81817.1 - 3.5e-36 124.6 0.5 5.6e-36 123.9 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KNZ81817.1 - 2.8e-23 82.4 0.3 7.4e-23 81.0 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KNZ81817.1 - 0.036 14.3 1.3 0.32 11.3 0.5 2.6 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ81817.1 - 0.12 12.1 0.1 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain CMS1 PF14617.6 KNZ81817.1 - 0.18 11.1 1.3 0.22 10.8 0.1 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CTP_transf_like PF01467.26 KNZ81818.1 - 0.079 13.1 0.1 0.81 9.9 0.1 2.5 1 1 0 1 1 1 0 Cytidylyltransferase-like WD40 PF00400.32 KNZ81819.1 - 1.5e-14 54.2 3.7 0.028 15.3 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 KNZ81819.1 - 0.038 12.6 0.3 1.8 7.1 0.3 3.0 2 2 1 3 3 3 0 Nucleoporin Nup120/160 p450 PF00067.22 KNZ81820.1 - 1.4e-67 228.5 0.0 1.6e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.19 KNZ81821.1 - 1e-50 172.9 0.0 5.2e-50 170.6 0.0 1.9 1 1 0 1 1 1 1 RNB domain Pkinase PF00069.25 KNZ81823.1 - 2.3e-42 145.2 0.0 1.8e-24 86.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81823.1 - 1.7e-18 66.8 0.0 3.1e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KNZ81823.1 - 0.0011 18.3 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KNZ81823.1 - 0.03 14.2 0.3 0.089 12.7 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Vps51 PF08700.11 KNZ81824.1 - 2.3e-24 85.3 3.2 3.3e-24 84.8 3.2 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 KNZ81824.1 - 0.0007 18.4 2.9 0.0009 18.0 2.9 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 KNZ81824.1 - 0.0015 18.7 5.0 0.0021 18.3 5.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 FlgN PF05130.12 KNZ81824.1 - 0.017 15.6 1.2 0.024 15.1 1.2 1.2 1 0 0 1 1 1 0 FlgN protein Yip1 PF04893.17 KNZ81826.1 - 1.8e-14 53.8 16.7 2.7e-14 53.2 16.7 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 KNZ81826.1 - 0.018 14.8 9.9 0.027 14.3 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) AAA PF00004.29 KNZ81827.1 - 9.4e-42 142.6 0.0 1.6e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KNZ81827.1 - 1.4e-11 44.2 0.0 3.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KNZ81827.1 - 1.3e-10 40.9 0.4 2.6e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KNZ81827.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KNZ81827.1 - 3.5e-05 24.1 0.2 0.028 14.7 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 KNZ81827.1 - 5e-05 22.6 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 KNZ81827.1 - 0.00026 21.4 0.4 0.011 16.1 0.1 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KNZ81827.1 - 0.0004 20.4 0.2 0.002 18.1 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KNZ81827.1 - 0.00066 19.5 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 KNZ81827.1 - 0.0014 18.2 0.6 0.0075 15.9 0.0 2.5 3 0 0 3 3 2 1 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 KNZ81827.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KNZ81827.1 - 0.0082 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KNZ81827.1 - 0.0092 15.4 0.2 0.35 10.2 0.1 2.2 1 1 0 2 2 2 1 KaiC AAA_18 PF13238.6 KNZ81827.1 - 0.015 15.8 1.0 0.019 15.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 KNZ81827.1 - 0.02 15.2 0.4 0.094 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 KNZ81827.1 - 0.024 14.6 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KNZ81827.1 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 KNZ81827.1 - 0.066 13.1 0.1 0.81 9.6 0.1 2.4 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 KNZ81827.1 - 0.083 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KNZ81827.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KNZ81827.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 KNZ81827.1 - 0.11 12.1 0.3 0.34 10.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KNZ81827.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KNZ81827.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KNZ81827.1 - 0.16 11.5 0.8 4.7 6.7 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 KNZ81827.1 - 0.18 11.5 0.4 0.41 10.3 0.4 1.6 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.19 KNZ81828.1 - 4.8e-12 45.8 0.1 6.8e-10 38.7 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 KNZ81828.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Squalene epoxidase SAA PF00277.18 KNZ81828.1 - 0.18 12.3 0.0 0.31 11.6 0.0 1.3 1 0 0 1 1 1 0 Serum amyloid A protein FAD_binding_3 PF01494.19 KNZ81829.1 - 1.6e-15 57.2 0.0 2.8e-14 53.2 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KNZ81829.1 - 0.0047 17.1 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 KNZ81829.1 - 0.02 14.0 0.1 0.094 11.8 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Amino_oxidase PF01593.24 KNZ81829.1 - 0.064 12.5 0.0 3.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KNZ81830.1 - 3.6e-11 42.9 0.3 1.5e-07 31.0 0.1 2.1 1 1 1 2 2 2 2 FAD binding domain SE PF08491.10 KNZ81830.1 - 0.034 13.2 0.1 0.17 10.9 0.0 2.0 2 1 0 2 2 2 0 Squalene epoxidase Med26 PF08711.11 KNZ81834.1 - 3.3e-10 39.8 1.9 1.1e-09 38.1 0.0 2.9 3 0 0 3 3 3 1 TFIIS helical bundle-like domain XRCC4 PF06632.12 KNZ81834.1 - 3.4 6.4 16.5 5.9 5.6 16.3 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TPR_19 PF14559.6 KNZ81837.1 - 4e-05 24.0 2.7 4.7e-05 23.8 0.4 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ81837.1 - 0.00063 19.7 2.8 2.9 8.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ81837.1 - 0.027 14.7 2.4 0.16 12.2 0.2 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 KNZ81837.1 - 0.03 15.2 0.1 0.72 10.8 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 KNZ81837.1 - 0.087 13.1 0.1 3.1 8.3 0.0 2.9 3 0 0 3 3 3 0 PPR repeat TPR_20 PF14561.6 KNZ81837.1 - 0.17 12.3 3.1 1.5 9.2 0.7 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat NMT1 PF09084.11 KNZ81838.1 - 0.00018 21.5 0.0 0.0012 18.9 0.0 2.0 1 1 1 2 2 2 2 NMT1/THI5 like NMT1_2 PF13379.6 KNZ81838.1 - 0.024 14.4 0.0 0.057 13.1 0.0 1.6 1 1 0 1 1 1 0 NMT1-like family NMT1_3 PF16868.5 KNZ81838.1 - 0.033 13.6 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 NMT1-like family GSHPx PF00255.19 KNZ81839.1 - 2.6e-41 139.5 0.1 3.4e-41 139.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KNZ81839.1 - 0.00065 19.6 0.0 0.0011 18.9 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KNZ81839.1 - 0.00081 19.1 0.1 0.005 16.6 0.0 2.0 2 0 0 2 2 2 1 Redoxin TMEM234 PF10639.9 KNZ81839.1 - 0.14 12.2 0.1 0.19 11.8 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 Phosphonate-bd PF12974.7 KNZ81839.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Mito_carr PF00153.27 KNZ81840.1 - 1.1e-07 31.7 0.0 3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial carrier protein ZYG-11_interact PF05884.12 KNZ81841.1 - 0.41 10.0 2.6 0.55 9.6 2.6 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 TPR_MLP1_2 PF07926.12 KNZ81841.1 - 6 6.9 23.1 0.21 11.7 16.2 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Metallophos PF00149.28 KNZ81842.1 - 1.3e-11 45.4 0.0 3e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 KNZ81842.1 - 0.0082 14.5 0.7 0.057 11.7 0.0 2.1 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase Retrotran_gag_2 PF14223.6 KNZ81843.1 - 2.2e-15 56.5 0.1 3.2e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FRD2 PF03197.13 KNZ81843.1 - 0.0017 18.6 0.2 0.011 16.0 0.0 2.1 2 0 0 2 2 2 1 Bacteriophage FRD2 protein Tyr-DNA_phospho PF06087.12 KNZ81843.1 - 0.032 13.1 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase ChaB PF06150.12 KNZ81843.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.9 3 0 0 3 3 3 0 ChaB LolB PF03550.14 KNZ81844.1 - 0.014 15.4 0.2 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB DUF4375 PF14300.6 KNZ81844.1 - 0.041 14.1 0.1 0.076 13.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) PAPA-1 PF04795.12 KNZ81844.1 - 0.072 13.9 0.7 0.072 13.9 0.7 2.0 1 1 1 2 2 2 0 PAPA-1-like conserved region Stork_head PF10264.9 KNZ81844.1 - 0.099 12.8 0.1 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Metallophos PF00149.28 KNZ81845.1 - 4.5e-36 125.3 0.6 6.3e-36 124.8 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KNZ81845.1 - 0.00049 20.5 0.1 0.001 19.5 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 KNZ81845.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-HYPF PF07503.12 KNZ81845.1 - 5.7 6.8 7.1 25 4.7 0.0 3.5 3 0 0 3 3 3 0 HypF finger Cpn60_TCP1 PF00118.24 KNZ81846.1 - 1.9e-153 511.7 0.8 2.2e-153 511.5 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COesterase PF00135.28 KNZ81847.1 - 2e-86 290.9 0.0 2.3e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ81847.1 - 1.1e-06 28.7 0.2 2.2e-05 24.4 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold UBA_4 PF14555.6 KNZ81847.1 - 0.0086 15.9 1.2 0.069 13.0 0.2 2.3 2 0 0 2 2 2 1 UBA-like domain Peptidase_S9 PF00326.21 KNZ81847.1 - 0.11 11.9 0.2 0.24 10.9 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family PfkB PF00294.24 KNZ81848.1 - 2.9e-12 46.5 0.0 0.00012 21.5 0.0 3.1 3 0 0 3 3 3 3 pfkB family carbohydrate kinase TPR_19 PF14559.6 KNZ81849.1 - 6.9e-17 61.7 4.0 1.2e-06 28.9 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ81849.1 - 1.8e-13 49.5 0.3 0.12 12.5 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ81849.1 - 2.1e-13 50.7 2.0 4.3e-07 30.5 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ81849.1 - 7.2e-11 41.4 0.1 0.19 11.6 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ81849.1 - 1.3e-09 38.0 10.5 0.014 16.2 0.1 6.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ81849.1 - 2.5e-08 33.7 0.0 0.007 16.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ81849.1 - 1.7e-06 28.1 0.0 0.035 14.3 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KNZ81849.1 - 1.5e-05 25.2 4.1 0.78 10.1 0.0 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 KNZ81849.1 - 1.7e-05 24.8 0.6 0.0065 16.5 0.0 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 KNZ81849.1 - 0.00011 22.5 1.4 0.34 11.3 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ81849.1 - 0.00026 21.4 4.2 35 5.3 0.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ81849.1 - 0.00058 19.9 0.1 1.8 8.9 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KNZ81849.1 - 0.00077 19.6 5.4 0.23 11.7 0.2 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 KNZ81849.1 - 0.0011 18.8 0.7 0.27 11.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ81849.1 - 0.0029 17.5 2.0 0.68 10.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ81849.1 - 0.0072 16.9 2.0 1.7 9.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KNZ81849.1 - 0.0076 15.9 0.2 0.44 10.3 0.0 3.2 3 1 1 4 4 4 1 TPR repeat Alkyl_sulf_dimr PF14863.6 KNZ81849.1 - 0.0097 16.4 0.1 0.056 13.9 0.0 2.2 2 1 1 3 3 2 1 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 KNZ81849.1 - 0.074 12.7 1.6 1.8 8.2 0.0 2.9 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 KNZ81849.1 - 0.1 11.8 0.1 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_assoc_2 PF16193.5 KNZ81849.1 - 0.11 12.9 0.0 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA C-terminal domain PDDEXK_9 PF08011.11 KNZ81851.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Peptidase_M48 PF01435.18 KNZ81852.1 - 1.9e-17 63.7 0.0 3.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF5643 PF18705.1 KNZ81853.1 - 0.00014 21.8 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5643) COX5B PF01215.19 KNZ81854.1 - 2.4e-47 159.8 0.0 3.2e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 KNZ81854.1 - 0.084 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain Na_Ca_ex PF01699.24 KNZ81855.1 - 3.7e-24 85.4 31.1 1.2e-19 70.8 17.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Lipase_GDSL_2 PF13472.6 KNZ81856.1 - 1.4e-16 61.4 1.5 1.7e-16 61.1 1.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KNZ81856.1 - 2.6e-07 30.8 0.0 3.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_M15_3 PF08291.11 KNZ81856.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase M15 PRK PF00485.18 KNZ81857.1 - 2.7e-48 164.4 0.0 3.7e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 KNZ81857.1 - 8.7e-45 152.7 0.0 8e-43 146.3 0.0 2.2 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 KNZ81857.1 - 7.3e-06 26.6 0.0 1.3e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KNZ81857.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 KNZ81857.1 - 0.00012 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KNZ81857.1 - 0.00057 20.3 0.5 0.0041 17.6 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KNZ81857.1 - 0.02 15.2 0.1 0.043 14.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KNZ81857.1 - 0.033 14.2 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 KNZ81857.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KNZ81857.1 - 0.085 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KNZ81857.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KNZ81857.1 - 0.16 12.4 0.0 0.69 10.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KNZ81857.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 KNZ81857.1 - 0.19 10.9 0.1 0.31 10.2 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain CoaE PF01121.20 KNZ81857.1 - 0.26 10.9 0.6 5.2 6.7 0.3 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase CTU2 PF10288.9 KNZ81858.1 - 2.2e-17 63.3 0.1 6.9e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 KNZ81858.1 - 0.0096 15.8 1.6 0.0096 15.8 1.6 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.14 KNZ81858.1 - 0.13 12.0 1.1 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 P-11 zinc finger ATP_bind_3 PF01171.20 KNZ81858.1 - 0.15 11.8 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 PP-loop family DUF2183 PF09949.9 KNZ81859.1 - 4.5e-25 87.9 0.0 7.8e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) GGACT PF06094.12 KNZ81860.1 - 6e-14 52.7 0.0 7.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like FRG PF08867.11 KNZ81861.1 - 0.0088 17.0 0.8 0.036 15.0 0.8 2.1 1 1 0 1 1 1 1 FRG domain ZapB PF06005.12 KNZ81861.1 - 0.1 13.1 12.4 15 6.1 9.4 3.5 1 1 0 2 2 2 0 Cell division protein ZapB DUF2203 PF09969.9 KNZ81861.1 - 0.12 13.1 6.4 0.12 13.1 0.8 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phage_GP20 PF06810.11 KNZ81861.1 - 0.2 11.5 6.7 0.1 12.4 1.9 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Prominin PF05478.11 KNZ81861.1 - 0.35 8.8 1.9 0.46 8.4 1.9 1.2 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.12 KNZ81861.1 - 1.1 9.8 6.3 38 4.9 1.4 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 KNZ81861.1 - 1.2 9.3 11.0 0.19 12.0 1.8 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5320 PF17253.2 KNZ81861.1 - 2.4 9.3 3.8 3 9.0 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5320) HisKA PF00512.25 KNZ81861.1 - 2.6 8.1 7.5 1.4 9.0 1.5 2.7 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain YabA PF06156.13 KNZ81861.1 - 2.9 8.6 7.0 24 5.7 0.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Metallophos PF00149.28 KNZ81862.1 - 2.4e-10 41.3 0.1 7.3e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KNZ81862.1 - 6.4e-05 23.2 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain EBV-NA3 PF05009.12 KNZ81862.1 - 0.054 13.0 0.7 10 5.5 0.0 2.5 2 1 1 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Peptidase_C14 PF00656.22 KNZ81863.1 - 3e-62 210.8 0.1 3.7e-62 210.5 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KNZ81863.1 - 0.054 13.5 0.0 0.32 11.0 0.0 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain TAF1D PF15333.6 KNZ81864.1 - 0.00028 20.7 0.0 0.00073 19.3 0.0 1.7 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D HSP20 PF00011.21 KNZ81865.1 - 3.7e-07 30.2 0.0 6.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family UvrD-helicase PF00580.21 KNZ81866.1 - 1.9e-62 211.6 0.0 3.3e-62 210.8 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KNZ81866.1 - 5.7e-61 206.8 0.0 1.8e-59 201.9 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KNZ81866.1 - 5.1e-32 111.2 0.0 1.1e-31 110.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KNZ81866.1 - 7.2e-13 48.2 0.0 1.8e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 KNZ81866.1 - 8.3e-10 38.8 0.2 0.0079 16.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KNZ81866.1 - 9.6e-06 25.4 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 KNZ81866.1 - 0.0011 18.8 0.1 0.0048 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KNZ81866.1 - 0.027 14.1 0.0 0.27 10.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain tRNA-synt_1g PF09334.11 KNZ81867.1 - 4.1e-134 447.2 0.0 5e-134 446.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 KNZ81867.1 - 4e-07 30.1 1.1 9.3e-07 28.9 1.1 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 KNZ81867.1 - 5e-05 21.8 0.0 0.00021 19.7 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KNZ81867.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zinc-ribbons_6 PF07191.12 KNZ81867.1 - 0.58 10.2 3.0 1.4 9.0 3.0 1.6 1 0 0 1 1 1 0 zinc-ribbons UPF0547 PF10571.9 KNZ81867.1 - 1.2 9.2 4.0 0.54 10.4 0.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DUF1272 PF06906.11 KNZ81867.1 - 2.5 8.3 4.8 0.83 9.8 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DZR PF12773.7 KNZ81867.1 - 3.7 7.6 6.4 11 6.1 6.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon OPT PF03169.15 KNZ81868.1 - 3e-135 452.3 23.0 3.6e-135 452.0 23.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3382 PF11862.8 KNZ81868.1 - 0.09 13.1 4.0 3.2 8.1 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) SARAF PF06682.12 KNZ81869.1 - 5.9e-59 200.4 0.0 7.4e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Cellulase PF00150.18 KNZ81870.1 - 4e-43 147.8 0.6 6.1e-43 147.3 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KNZ81870.1 - 9.5e-10 38.3 7.0 9.5e-10 38.3 7.0 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain MSP1_C PF07462.11 KNZ81870.1 - 0.21 10.3 1.3 0.35 9.5 1.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cellulase PF00150.18 KNZ81871.1 - 2e-42 145.5 0.4 3e-42 145.0 0.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KNZ81871.1 - 4.9e-09 36.0 5.4 4.9e-09 36.0 5.4 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Sporozoite_P67 PF05642.11 KNZ81871.1 - 3.1 5.8 6.6 4.5 5.2 6.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 KNZ81872.1 - 2.4e-23 82.7 13.4 3.7e-20 72.1 6.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KNZ81874.1 - 8.2e-13 48.0 15.1 8.2e-13 48.0 15.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Bud13 PF09736.9 KNZ81875.1 - 1.2e-53 181.4 8.5 1.2e-53 181.4 8.5 3.3 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Sad1_UNC PF07738.13 KNZ81875.1 - 1.5e-21 76.8 0.0 6.1e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal SQHop_cyclase_C PF13243.6 KNZ81875.1 - 0.17 11.0 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Abhydrolase_1 PF00561.20 KNZ81876.1 - 7.7e-36 124.1 0.0 9.7e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KNZ81876.1 - 1.2e-11 44.3 0.0 4e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KNZ81876.1 - 3e-10 41.1 0.1 3.9e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KNZ81876.1 - 0.00051 19.6 0.0 0.75 9.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ndr PF03096.14 KNZ81876.1 - 0.02 13.6 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Ndr family CRAL_TRIO PF00650.20 KNZ81877.1 - 1.3e-27 96.5 0.0 1.9e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ81877.1 - 6.6e-16 58.2 0.4 1.5e-15 57.1 0.4 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KNZ81877.1 - 0.016 15.4 0.0 0.036 14.2 0.0 1.6 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain RhoGEF PF00621.20 KNZ81878.1 - 1.4e-29 103.6 0.5 2.3e-29 102.9 0.5 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.22 KNZ81878.1 - 4.8e-23 82.1 0.0 6.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH PF00169.29 KNZ81878.1 - 0.14 12.6 0.0 0.59 10.7 0.0 2.2 1 1 0 1 1 1 0 PH domain Cu-oxidase PF00394.22 KNZ81880.1 - 1.1e-38 132.9 0.5 4.1e-37 127.8 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KNZ81880.1 - 3.3e-35 120.7 1.8 7.8e-29 100.1 0.1 3.4 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.14 KNZ81880.1 - 8.8e-35 119.4 1.1 1.7e-33 115.3 0.5 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KNZ81880.1 - 0.0083 16.2 0.0 11 6.2 0.0 3.4 3 1 0 3 3 3 2 Cupredoxin-like domain DUF155 PF02582.14 KNZ81881.1 - 7.5e-45 153.2 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 WD40 PF00400.32 KNZ81881.1 - 3.9e-33 113.0 7.8 8.9e-09 35.9 0.2 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ81881.1 - 6.9e-14 51.9 0.0 0.01 16.1 0.0 5.7 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ81881.1 - 1e-05 24.7 0.0 0.069 12.1 0.0 2.9 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 KNZ81881.1 - 0.058 11.8 0.0 0.09 11.1 0.0 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family WD40_like PF17005.5 KNZ81881.1 - 0.064 12.6 0.0 6.5 6.0 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Thioredoxin PF00085.20 KNZ81882.1 - 3.8e-55 184.2 0.3 1.7e-28 98.6 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KNZ81882.1 - 4.6e-24 85.1 0.2 1e-23 84.0 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KNZ81882.1 - 8.7e-18 64.8 0.5 1e-08 35.6 0.2 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KNZ81882.1 - 7.3e-14 51.8 0.0 1.2e-06 28.1 0.0 2.5 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KNZ81882.1 - 3.9e-11 43.1 0.2 0.0033 17.7 0.0 4.2 2 2 2 4 4 4 4 Thioredoxin-like Thioredoxin_7 PF13899.6 KNZ81882.1 - 5.7e-11 42.4 0.0 0.00013 22.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 KNZ81882.1 - 2.6e-10 40.3 0.1 0.00098 19.0 0.0 2.6 2 1 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.13 KNZ81882.1 - 8.1e-09 35.7 0.2 0.00017 21.8 0.1 2.4 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 KNZ81882.1 - 2e-06 27.9 1.4 0.046 13.6 0.6 3.0 1 1 2 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 KNZ81882.1 - 6.1e-06 26.2 0.0 0.047 13.5 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KNZ81882.1 - 2.6e-05 24.0 0.6 0.11 12.2 0.2 2.3 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 KNZ81882.1 - 0.00047 20.1 0.0 1.2 9.1 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KNZ81882.1 - 0.00066 19.5 0.0 0.66 9.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_5 PF13743.6 KNZ81882.1 - 0.001 18.8 1.2 1.6 8.4 0.0 3.4 2 2 2 4 4 4 2 Thioredoxin Glutaredoxin PF00462.24 KNZ81882.1 - 0.005 17.0 4.7 0.081 13.2 0.1 3.4 3 2 0 3 3 3 1 Glutaredoxin DUF836 PF05768.14 KNZ81882.1 - 0.014 15.8 0.0 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 KNZ81882.1 - 0.05 13.8 2.1 13 5.9 0.2 3.3 3 1 0 4 4 4 0 Thioredoxin HZS_alpha PF18582.1 KNZ81884.1 - 0.15 12.5 0.0 0.34 11.4 0.0 1.6 1 0 0 1 1 1 0 Hydrazine synthase alpha subunit middle domain Sugar_tr PF00083.24 KNZ81885.1 - 8.6e-73 245.7 21.2 9.8e-73 245.5 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ81885.1 - 1.8e-22 79.8 41.8 9.2e-21 74.1 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 KNZ81886.1 - 8.6e-14 51.8 5.1 2.9e-13 50.1 0.0 3.5 2 1 1 3 3 3 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 KNZ81886.1 - 0.0027 16.0 0.0 0.085 11.0 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 70 Fmp27 PF10344.9 KNZ81886.1 - 2.7 6.0 6.7 5.1 5.1 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Sugar_tr PF00083.24 KNZ81887.1 - 2.7e-113 379.2 25.5 3.6e-113 378.8 25.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ81887.1 - 7.8e-23 81.0 51.6 1.5e-16 60.3 17.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 KNZ81890.1 - 0.2 11.6 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial carrier protein Brix PF04427.18 KNZ81891.1 - 1.7e-40 139.2 0.1 2.4e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Brix domain ADH_N_2 PF16884.5 KNZ81892.1 - 1.3e-26 92.6 0.0 2.3e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KNZ81892.1 - 6e-17 61.8 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KNZ81892.1 - 0.00024 22.2 0.0 0.00049 21.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.16 KNZ81892.1 - 0.027 13.9 0.0 0.057 12.9 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein ADH_N PF08240.12 KNZ81892.1 - 0.18 11.7 0.4 3.4 7.6 0.0 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MIP PF00230.20 KNZ81894.1 - 5.5e-23 81.9 6.0 7.1e-23 81.5 6.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein SART-1 PF03343.13 KNZ81895.1 - 1.9e-165 552.0 57.8 1.5e-164 549.0 54.1 2.0 2 0 0 2 2 2 2 SART-1 family LsmAD PF06741.13 KNZ81896.1 - 2.8e-28 98.2 0.4 5.3e-28 97.4 0.4 1.5 1 0 0 1 1 1 1 LsmAD domain MID_MedPIWI PF18296.1 KNZ81896.1 - 0.11 12.2 2.0 0.19 11.5 2.0 1.4 1 0 0 1 1 1 0 MID domain of medPIWI DUF3716 PF12511.8 KNZ81899.1 - 0.0054 16.8 0.9 0.011 15.7 0.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) Pkinase PF00069.25 KNZ81900.1 - 2.9e-14 53.1 0.0 1.4e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81900.1 - 3.9e-06 26.3 0.0 0.00043 19.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KNZ81900.1 - 0.02 14.8 0.1 0.046 13.6 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 KNZ81900.1 - 0.043 13.2 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I PF08311.12 KNZ81901.1 - 4e-17 62.3 0.2 4e-17 62.3 0.2 1.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KNZ81901.1 - 2.2e-12 46.9 0.0 7.9e-10 38.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81901.1 - 2.1e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.11 KNZ81901.1 - 0.00034 20.7 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 KNZ81901.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Terpene_synth_C PF03936.16 KNZ81902.1 - 5e-08 32.6 0.4 9.5e-08 31.7 0.4 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Phosphorylase PF00343.20 KNZ81903.1 - 0.097 10.9 0.1 0.13 10.5 0.1 1.1 1 0 0 1 1 1 0 Carbohydrate phosphorylase p450 PF00067.22 KNZ81905.1 - 3.6e-43 148.0 0.0 6.3e-43 147.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF1229 PF06797.11 KNZ81906.1 - 0.0045 17.2 0.1 0.0061 16.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1229) TssN PF17555.2 KNZ81906.1 - 0.2 11.0 3.7 0.14 11.5 0.6 1.8 1 1 1 2 2 2 0 Type VI secretion system, TssN CRPA PF05745.11 KNZ81906.1 - 1.6 8.8 6.1 0.66 10.0 3.9 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) YrvL PF14184.6 KNZ81906.1 - 4 7.6 8.8 6.5 6.9 5.9 2.0 2 0 0 2 2 2 0 Regulatory protein YrvL DUF1772 PF08592.11 KNZ81906.1 - 7 7.0 7.7 1.4e+02 2.7 7.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) Xpo1 PF08389.12 KNZ81909.1 - 2.4e-17 63.4 4.4 1.1e-16 61.2 0.0 4.1 5 1 0 5 5 5 1 Exportin 1-like protein HEAT PF02985.22 KNZ81909.1 - 0.0074 16.4 1.3 6 7.4 0.2 4.2 2 1 1 3 3 3 2 HEAT repeat RPAP3_C PF13877.6 KNZ81909.1 - 0.046 14.3 1.7 0.55 10.8 0.1 3.3 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 Cullin PF00888.22 KNZ81910.1 - 6.4e-195 649.3 0.0 7.8e-195 649.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KNZ81910.1 - 2.1e-28 98.1 0.7 5.2e-28 96.9 0.7 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DnaJ_C PF01556.18 KNZ81911.1 - 6.2e-29 101.0 0.0 8.9e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KNZ81911.1 - 2e-24 85.5 4.2 3.2e-24 84.8 4.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KNZ81911.1 - 8.8e-15 54.8 15.8 1.6e-14 54.0 15.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KNZ81911.1 - 2.1e-05 24.4 8.2 0.011 15.7 1.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KNZ81911.1 - 3.2e-05 23.9 4.5 0.018 15.0 1.3 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KNZ81911.1 - 0.043 14.2 10.2 0.084 13.3 0.3 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar TackOD1 PF18551.1 KNZ81911.1 - 0.63 9.7 6.2 0.17 11.5 0.3 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_6 PF14599.6 KNZ81911.1 - 0.73 9.9 5.7 0.77 9.8 0.5 2.5 2 0 0 2 2 2 0 Zinc-ribbon DZR PF12773.7 KNZ81911.1 - 2 8.5 10.1 12 6.0 10.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KNZ81911.1 - 2.7 7.6 4.9 22 4.6 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zf-RING_5 PF14634.6 KNZ81911.1 - 5.9 6.9 8.6 6.4 6.8 1.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain WLM PF08325.10 KNZ81913.1 - 3.4e-24 86.0 0.8 2.6e-23 83.1 0.8 2.1 1 1 0 1 1 1 1 WLM domain TRF PF08558.10 KNZ81913.1 - 0.062 12.9 0.6 0.1 12.2 0.6 1.3 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) DUF3421 PF11901.8 KNZ81914.1 - 3.5e-17 62.4 0.2 4e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Dimer_Tnp_hAT PF05699.14 KNZ81915.1 - 2.9e-07 30.2 0.0 3.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TPR_1 PF00515.28 KNZ81915.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 KNZ81916.1 - 1.4e-31 109.9 24.3 4.8e-17 62.0 6.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ81916.1 - 1.1e-14 54.2 44.6 1.8e-08 33.7 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 KNZ81916.1 - 0.0077 16.0 6.0 0.0077 16.0 6.0 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 PRTase_1 PF11202.8 KNZ81916.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) DSS1_SEM1 PF05160.13 KNZ81917.1 - 4.4e-24 84.3 7.6 6.8e-24 83.7 7.6 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family SIR2 PF02146.17 KNZ81918.1 - 9e-33 113.7 0.0 2.1e-32 112.5 0.0 1.6 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 KNZ81918.1 - 0.043 13.6 0.1 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain 6PF2K PF01591.18 KNZ81920.1 - 1.8e-69 233.5 0.0 2.8e-69 232.8 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KNZ81920.1 - 7.2e-31 107.4 0.0 1.4e-30 106.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 KNZ81920.1 - 5.1e-20 71.9 0.0 5.8e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81920.1 - 9.8e-09 34.9 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ81920.1 - 2.4e-08 33.2 0.1 4e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase AAA_33 PF13671.6 KNZ81920.1 - 0.00024 21.3 0.0 0.00061 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KNZ81920.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Protoglobin PF11563.8 KNZ81921.1 - 1.2e-49 168.2 0.0 1.4e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Protoglobin NAD_binding_10 PF13460.6 KNZ81922.1 - 7.5e-05 22.7 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KNZ81922.1 - 0.0084 15.7 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KNZ81922.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Asp PF00026.23 KNZ81923.1 - 2.6e-60 204.5 0.0 5e-60 203.6 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KNZ81923.1 - 7.5e-14 52.4 0.0 2.7e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KNZ81923.1 - 0.00026 21.6 0.2 4.8 7.9 0.0 3.7 2 1 1 3 3 3 2 Aspartyl protease DUF285 PF03382.14 KNZ81925.1 - 0.037 13.8 2.3 0.06 13.1 2.3 1.4 1 1 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DASH_Spc19 PF08287.11 KNZ81926.1 - 1.3 8.9 3.5 0.69 9.8 0.8 1.7 2 0 0 2 2 2 0 Spc19 p450 PF00067.22 KNZ81927.1 - 2.8e-39 135.1 0.0 5.9e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.10 KNZ81927.1 - 0.011 16.1 0.2 0.037 14.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) DUF2370 PF10176.9 KNZ81931.1 - 5e-52 176.8 0.7 2.1e-51 174.7 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) Dehydrin PF00257.19 KNZ81931.1 - 0.039 14.5 0.2 0.29 11.7 0.0 2.0 2 0 0 2 2 2 0 Dehydrin p450 PF00067.22 KNZ81932.1 - 5.2e-56 190.3 0.0 9.8e-56 189.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1771 PF08590.10 KNZ81932.1 - 0.048 14.1 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Helitron_like_N PF14214.6 KNZ81936.1 - 8.3e-13 49.0 0.1 1.1e-12 48.5 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MitMem_reg PF13012.6 KNZ81937.1 - 0.058 13.8 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function Herpes_Helicase PF02689.14 KNZ81938.1 - 1.2e-05 23.5 0.0 1.3e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Helicase ADH_zinc_N PF00107.26 KNZ81939.1 - 4.7e-22 78.3 0.4 8.2e-22 77.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KNZ81939.1 - 5.8e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 KNZ81939.1 - 0.00015 22.8 0.0 0.00027 22.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KNZ81939.1 - 0.059 13.1 0.2 0.66 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) RNase_H PF00075.24 KNZ81942.1 - 0.00038 20.7 0.2 0.00099 19.3 0.1 1.7 2 0 0 2 2 2 1 RNase H Aldedh PF00171.22 KNZ81943.1 - 1.5e-151 505.0 0.0 1.9e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF5351 PF17302.2 KNZ81944.1 - 2.4e-05 24.4 2.0 2.4e-05 24.4 2.0 2.5 3 0 0 3 3 3 1 Family of unknown function (DUF5351) DnaJ_CXXCXGXG PF00684.19 KNZ81944.1 - 0.09 13.2 0.5 0.09 13.2 0.5 3.0 2 1 0 2 2 2 0 DnaJ central domain Anti-TRAP PF15777.5 KNZ81944.1 - 1.5 8.8 7.3 0.85 9.6 1.4 3.0 3 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Aminotran_5 PF00266.19 KNZ81945.1 - 1.5e-50 172.3 0.0 2.6e-50 171.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_S41_N PF11918.8 KNZ81946.1 - 0.0043 17.3 0.2 0.0054 17.0 0.2 1.2 1 0 0 1 1 1 1 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF3501 PF12007.8 KNZ81946.1 - 0.03 14.3 0.9 0.034 14.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) Transpos_assoc PF13963.6 KNZ81946.1 - 3.2 8.1 8.9 0.72 10.2 3.6 2.1 1 1 1 2 2 2 0 Transposase-associated domain TauD PF02668.16 KNZ81948.1 - 2.4e-47 162.0 0.4 3e-47 161.7 0.4 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KNZ81948.1 - 0.0057 15.8 0.0 0.038 13.1 0.0 1.9 1 1 0 1 1 1 1 CsiD VRR_NUC PF08774.11 KNZ81949.1 - 3.5e-22 78.5 0.0 8.4e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain HMG_box PF00505.19 KNZ81950.1 - 8.6e-06 26.1 0.9 1.9e-05 25.0 0.9 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box PhoLip_ATPase_C PF16212.5 KNZ81951.1 - 2.3e-57 194.6 24.7 3.6e-55 187.4 13.0 3.2 2 1 1 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 KNZ81951.1 - 2.6e-13 50.7 0.2 2e-06 28.3 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ81951.1 - 2.7e-10 40.2 0.0 1.2e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KNZ81951.1 - 0.00016 21.5 0.9 0.0084 15.9 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 KNZ81951.1 - 0.24 11.1 0.9 0.55 9.9 0.9 1.7 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal YtpI PF14007.6 KNZ81951.1 - 3.2 7.9 5.5 0.56 10.4 0.1 2.5 3 0 0 3 3 3 0 YtpI-like protein Septin PF00735.18 KNZ81952.1 - 4.6e-110 367.3 2.5 4.6e-110 367.3 2.5 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KNZ81952.1 - 6.7e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KNZ81952.1 - 7.8e-07 29.1 0.9 1.5e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KNZ81952.1 - 8.6e-05 22.2 1.0 0.012 15.2 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KNZ81952.1 - 0.0004 19.8 0.0 0.00096 18.5 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 KNZ81952.1 - 0.0057 16.7 2.3 2.2 8.3 0.0 2.8 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 KNZ81952.1 - 0.014 15.9 0.1 0.029 14.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KNZ81952.1 - 0.063 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KNZ81952.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 KNZ81952.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Cerato-platanin PF07249.12 KNZ81953.1 - 3.2e-43 146.6 0.5 3.9e-43 146.3 0.5 1.0 1 0 0 1 1 1 1 Cerato-platanin Regulator_TrmB PF11495.8 KNZ81953.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Cerato-platanin PF07249.12 KNZ81954.1 - 7.1e-25 87.4 1.7 1e-11 45.0 0.2 2.0 1 1 1 2 2 2 2 Cerato-platanin Adap_comp_sub PF00928.21 KNZ81955.1 - 1.3e-82 277.2 0.0 1.6e-82 276.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KNZ81955.1 - 9.5e-07 28.8 2.2 1.7e-06 28.1 2.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF11 PF01345.18 KNZ81955.1 - 0.016 15.5 4.5 0.047 14.0 4.5 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF11 DUF5618 PF18498.1 KNZ81955.1 - 0.03 14.5 0.3 0.086 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5618) Pentapeptide_3 PF13576.6 KNZ81955.1 - 0.29 11.3 2.4 23 5.3 0.3 3.0 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) Lipase_GDSL PF00657.22 KNZ81956.1 - 0.028 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Globin PF00042.22 KNZ81956.1 - 0.04 14.5 0.0 0.062 13.9 0.0 1.4 1 0 0 1 1 1 0 Globin TPP_enzyme_N PF02776.18 KNZ81957.1 - 9e-56 188.2 0.1 4.4e-55 185.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KNZ81957.1 - 3.2e-48 163.4 0.2 1e-46 158.5 0.2 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KNZ81957.1 - 4.2e-41 139.9 0.4 1.3e-40 138.3 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Jacalin PF01419.17 KNZ81958.1 - 1.1e-06 28.6 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.23 KNZ81958.1 - 0.00062 19.4 1.1 0.0014 18.2 1.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KNZ81958.1 - 0.16 11.8 0.1 4 7.3 0.0 2.8 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Jacalin PF01419.17 KNZ81960.1 - 8.3e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.23 KNZ81960.1 - 0.00018 21.1 2.4 0.00079 19.0 2.4 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PhoLip_ATPase_C PF16212.5 KNZ81961.1 - 2.8e-63 214.0 39.8 1.3e-62 211.8 33.2 3.2 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KNZ81961.1 - 1.4e-21 75.9 3.7 1.6e-21 75.7 2.0 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KNZ81961.1 - 1.8e-11 44.8 0.5 1.5e-08 35.2 0.5 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KNZ81961.1 - 4.9e-10 39.4 0.0 1.4e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KNZ81961.1 - 0.00016 21.3 0.0 0.00016 21.3 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KNZ81961.1 - 0.0013 18.5 1.5 0.019 14.7 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_17 PF00332.18 KNZ81962.1 - 2e-05 24.3 0.1 3.5e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RT_RNaseH PF17917.1 KNZ81963.1 - 4.9e-07 30.0 0.0 1.1e-06 28.9 0.0 1.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ81963.1 - 2.1e-05 24.5 0.0 3.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF1919 PF08942.10 KNZ81963.1 - 0.15 11.5 0.4 0.25 10.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) Integrase_H2C2 PF17921.1 KNZ81964.1 - 3.8e-08 33.3 1.0 5.4e-08 32.8 1.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain DUF570 PF04489.13 KNZ81971.1 - 0.041 12.5 0.3 0.19 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF570) RVP_2 PF08284.11 KNZ81972.1 - 0.0014 18.4 0.1 0.008 16.0 0.1 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease Pkinase PF00069.25 KNZ81973.1 - 1.4e-07 31.1 0.0 3.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ81973.1 - 0.055 12.7 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase DUF4164 PF13747.6 KNZ81974.1 - 0.025 14.8 0.2 0.084 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) AIM3 PF17096.5 KNZ81974.1 - 0.16 13.0 1.2 0.52 11.3 0.4 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 MFS_1 PF07690.16 KNZ81975.1 - 8.7e-19 67.6 28.9 9.5e-17 60.9 13.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DAD PF02109.16 KNZ81975.1 - 0.085 13.2 0.2 0.3 11.4 0.2 1.9 1 0 0 1 1 1 0 DAD family Cofilin_ADF PF00241.20 KNZ81976.1 - 3.2e-19 68.9 0.0 3.5e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Mannosyl_trans PF05007.13 KNZ81977.1 - 8.4e-75 252.0 10.6 1.2e-74 251.5 10.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KNZ81977.1 - 7.9e-15 54.8 1.4 7.9e-15 54.8 1.4 1.9 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Arf PF00025.21 KNZ81978.1 - 3.1e-57 192.8 0.0 3.8e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KNZ81978.1 - 4.3e-09 36.0 0.0 2.2e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KNZ81978.1 - 4.8e-09 35.9 0.0 6.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KNZ81978.1 - 2.9e-06 27.5 0.0 1.3e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KNZ81978.1 - 5.6e-06 26.4 0.0 7.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KNZ81978.1 - 2.7e-05 23.8 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KNZ81978.1 - 0.0068 15.8 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KNZ81978.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 KNZ81979.1 - 1.9e-66 222.8 0.0 2.3e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KNZ81979.1 - 1.5e-10 40.8 0.0 2.9e-07 30.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KNZ81979.1 - 6.1e-10 38.8 0.0 8e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KNZ81979.1 - 2.6e-07 30.9 0.0 6e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KNZ81979.1 - 5.3e-07 29.7 0.0 9.8e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 KNZ81979.1 - 8.9e-06 25.4 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KNZ81979.1 - 0.00021 20.7 0.0 0.00026 20.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 KNZ81979.1 - 0.069 12.9 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KNZ81979.1 - 0.14 11.8 0.0 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain COesterase PF00135.28 KNZ81980.1 - 1.3e-92 311.3 0.0 4.8e-91 306.1 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KNZ81980.1 - 9.1e-06 25.7 0.3 0.00013 21.8 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KNZ81980.1 - 0.00072 19.1 0.5 0.0016 17.9 0.4 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Pkinase_fungal PF17667.1 KNZ81981.1 - 4e-19 68.7 0.0 4.1e-13 48.9 0.0 3.1 3 0 0 3 3 3 3 Fungal protein kinase Utp21 PF04192.12 KNZ81982.1 - 1.4e-63 214.5 0.4 2.3e-63 213.8 0.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 KNZ81982.1 - 9.1e-16 57.9 0.0 0.00059 20.1 0.0 7.1 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KNZ81982.1 - 4.5e-15 55.8 14.5 0.029 15.2 0.0 10.2 11 0 0 11 11 11 3 WD domain, G-beta repeat Hira PF07569.11 KNZ81982.1 - 0.00011 22.0 2.9 0.41 10.3 0.0 4.7 4 1 1 5 5 5 1 TUP1-like enhancer of split Ge1_WD40 PF16529.5 KNZ81982.1 - 0.19 10.7 0.0 41 3.0 0.0 3.5 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KNZ81982.1 - 0.4 9.4 3.5 3.5 6.3 0.1 2.9 2 1 1 3 3 3 0 Nup133 N terminal like SAPS PF04499.15 KNZ81983.1 - 2.4e-115 386.1 0.0 3.7e-115 385.5 0.0 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein FAA_hydrolase PF01557.18 KNZ81984.1 - 5.8e-58 196.1 0.0 7.1e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 KNZ81984.1 - 0.0019 18.0 0.3 0.0059 16.4 0.0 1.8 2 0 0 2 2 2 1 KH domain Amidohydro_2 PF04909.14 KNZ81985.1 - 6.7e-24 85.2 0.0 8.3e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DUF4229 PF14012.6 KNZ81986.1 - 0.094 12.8 2.0 0.36 11.0 2.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) PAP_assoc PF03828.19 KNZ81987.1 - 9.3e-18 64.2 0.1 9.3e-18 64.2 0.1 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KNZ81987.1 - 8.9e-10 38.7 0.0 2.3e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KNZ81987.1 - 0.019 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Helitron_like_N PF14214.6 KNZ81989.1 - 3e-16 60.2 0.1 3.6e-16 59.9 0.1 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Helitron_like_N PF14214.6 KNZ81990.1 - 2.4e-25 89.9 0.1 3.1e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MitMem_reg PF13012.6 KNZ81991.1 - 0.055 13.9 0.0 0.056 13.9 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function PIF1 PF05970.14 KNZ81992.1 - 2.9e-39 135.3 0.0 3.2e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ81992.1 - 0.00054 19.7 0.0 0.00064 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KNZ81992.1 - 0.002 18.2 0.0 0.0051 16.8 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ81992.1 - 0.004 17.6 0.0 0.0046 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KNZ81992.1 - 0.061 12.9 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 KNZ81992.1 - 0.072 11.9 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Viral_helicase1 PF01443.18 KNZ81992.1 - 0.081 12.6 0.2 0.11 12.2 0.2 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KNZ81992.1 - 0.11 12.9 0.1 0.6 10.5 0.1 2.0 1 1 0 1 1 1 0 RNA helicase CENP-C_C PF11699.8 KNZ81993.1 - 2e-15 56.7 0.1 3.5e-15 56.0 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.12 KNZ81993.1 - 0.0077 15.9 0.1 0.018 14.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 KNZ81993.1 - 0.0093 15.7 0.1 0.022 14.5 0.1 1.7 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 KNZ81993.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain HNH_2 PF13391.6 KNZ81994.1 - 0.021 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 HNH endonuclease CTP_transf_1 PF01148.20 KNZ81994.1 - 0.069 12.9 1.3 0.12 12.2 1.3 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family DUF1964 PF09244.10 KNZ81994.1 - 0.18 12.2 0.4 0.64 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1964) DUF2613 PF11021.8 KNZ81994.1 - 5.7 7.1 7.7 0.69 10.1 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Exo_endo_phos_2 PF14529.6 KNZ81996.1 - 0.01 15.7 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase CHZ PF09649.10 KNZ81996.1 - 0.33 10.5 1.6 0.68 9.4 1.6 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ RNase_H PF00075.24 KNZ81997.1 - 0.0017 18.6 0.1 0.013 15.6 0.1 2.2 1 1 0 1 1 1 1 RNase H DEAD_assoc PF08494.11 KNZ81998.1 - 0.11 12.2 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 DEAD/H associated Integrase_H2C2 PF17921.1 KNZ81999.1 - 2.1e-08 34.2 0.9 5.5e-08 32.8 0.9 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain Myb_DNA-bind_2 PF08914.11 KNZ82000.1 - 0.17 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Rap1 Myb domain SecD_SecF PF02355.16 KNZ82000.1 - 8.2 5.8 10.1 1.2e+02 1.9 10.1 2.1 1 1 0 1 1 1 0 Protein export membrane protein Orn_Arg_deC_N PF02784.16 KNZ82001.1 - 6.2e-76 255.0 0.0 7.8e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KNZ82001.1 - 4.9e-14 52.4 0.0 6.3e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Mlf1IP PF10248.9 KNZ82001.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Ribosomal_S17e PF00833.18 KNZ82002.1 - 3.9e-45 152.7 0.1 1.3e-44 151.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal S17 zf-C2H2 PF00096.26 KNZ82002.1 - 1.4e-05 25.2 1.2 0.02 15.3 0.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ82002.1 - 0.00012 22.6 1.4 0.13 13.2 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KNZ82002.1 - 0.017 15.4 0.8 0.14 12.5 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KNZ82002.1 - 0.19 12.1 2.0 0.92 9.9 2.0 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_S8 PF00410.19 KNZ82003.1 - 4.2e-25 88.2 0.1 5.3e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Orn_Arg_deC_N PF02784.16 KNZ82004.1 - 2.2e-75 253.2 0.0 2.7e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KNZ82004.1 - 4.4e-15 55.7 0.0 5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain G-alpha PF00503.20 KNZ82005.1 - 7.4e-111 370.7 0.0 8.5e-111 370.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ82005.1 - 9.8e-15 54.4 0.4 5.1e-09 35.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KNZ82005.1 - 0.00062 19.2 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KNZ82005.1 - 0.023 14.9 1.3 1.6 8.9 0.3 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KNZ82005.1 - 0.07 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_10 PF13374.6 KNZ82006.1 - 4.3e-101 328.5 3.9 7.2e-10 38.4 0.0 14.4 14 1 0 14 14 14 13 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ82006.1 - 1.2e-91 301.0 51.1 8e-16 58.1 0.4 11.9 2 1 12 14 14 13 13 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ82006.1 - 2.7e-19 69.7 41.7 3.4e-12 46.4 10.0 4.9 1 1 4 5 5 5 5 MalT-like TPR region TPR_17 PF13431.6 KNZ82006.1 - 1.2e-13 50.3 4.4 7.7 7.1 0.0 10.9 12 0 0 12 12 10 0 Tetratricopeptide repeat Patatin PF01734.22 KNZ82006.1 - 5.1e-12 46.4 0.0 1.6e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_7 PF13176.6 KNZ82006.1 - 3.5e-10 39.2 15.5 0.16 12.1 0.1 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ82006.1 - 6.8e-10 38.3 26.1 1.5 9.1 0.3 11.0 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 KNZ82006.1 - 9.9e-10 38.8 34.2 0.13 12.8 1.4 10.5 6 3 6 12 12 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ82006.1 - 3.9e-09 36.0 31.2 1.5 9.2 0.1 12.4 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_3 PF07720.12 KNZ82006.1 - 1.7e-06 27.9 10.6 3.8 7.6 0.1 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ82006.1 - 3.4e-06 26.5 6.5 1.2 8.3 0.0 7.2 6 2 1 8 8 8 2 Tetratricopeptide repeat TPR_5 PF12688.7 KNZ82006.1 - 0.00015 22.0 21.8 3.9 7.7 1.2 7.7 4 1 2 7 7 7 2 Tetratrico peptide repeat DUF4404 PF14357.6 KNZ82006.1 - 0.00019 22.0 17.4 5.2 7.8 0.0 8.2 3 2 4 8 8 8 1 Domain of unknown function (DUF4404) TPR_20 PF14561.6 KNZ82006.1 - 0.00027 21.2 18.2 0.96 9.8 1.0 8.8 3 2 5 8 8 8 1 Tetratricopeptide repeat AAA_7 PF12775.7 KNZ82006.1 - 0.00037 20.1 0.2 0.012 15.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 KNZ82006.1 - 0.00073 19.8 0.0 0.0044 17.3 0.0 2.4 1 0 0 1 1 1 1 AAA domain OLF PF02191.16 KNZ82006.1 - 0.00081 19.0 0.0 0.032 13.8 0.0 2.6 2 0 0 2 2 2 1 Olfactomedin-like domain AAA_16 PF13191.6 KNZ82006.1 - 0.0013 19.2 0.2 0.0078 16.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 KNZ82006.1 - 0.0017 17.6 0.5 0.033 13.4 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain TPR_1 PF00515.28 KNZ82006.1 - 0.028 14.3 18.5 27 4.8 0.0 9.7 11 0 0 11 11 11 0 Tetratricopeptide repeat AAA_5 PF07728.14 KNZ82006.1 - 0.093 12.7 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPR_4 PF07721.14 KNZ82006.1 - 0.2 12.4 17.2 94 4.1 0.0 8.5 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ82006.1 - 0.37 11.5 4.6 71 4.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DPM3 PF08285.11 KNZ82006.1 - 0.52 10.5 7.0 16 5.8 0.0 5.2 5 0 0 5 5 5 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PH PF00169.29 KNZ82007.1 - 5.2e-05 23.7 0.0 9.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PH domain C12orf66_like PF09404.10 KNZ82007.1 - 0.044 12.6 0.6 0.064 12.1 0.6 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like Orthopox_A5L PF06193.11 KNZ82007.1 - 0.048 13.1 0.4 0.048 13.1 0.4 1.8 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Pho88 PF10032.9 KNZ82008.1 - 4e-72 241.3 0.2 4.5e-72 241.1 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TPR_10 PF13374.6 KNZ82009.1 - 3.8e-85 277.7 3.8 3e-09 36.4 0.2 12.8 12 1 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ82009.1 - 1e-82 272.4 42.7 5.8e-13 48.9 0.1 10.4 2 1 10 12 12 12 11 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ82009.1 - 3.3e-15 56.3 37.7 6.1e-08 32.4 13.5 4.2 1 1 3 4 4 4 4 MalT-like TPR region TPR_19 PF14559.6 KNZ82009.1 - 3.9e-15 56.1 23.7 0.13 12.8 0.4 9.9 4 4 7 11 11 11 6 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ82009.1 - 4e-14 51.9 0.9 3.4 8.3 0.0 10.4 11 0 0 11 11 11 1 Tetratricopeptide repeat Patatin PF01734.22 KNZ82009.1 - 2.1e-11 44.4 0.0 7.7e-11 42.5 0.0 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_2 PF07719.17 KNZ82009.1 - 2.9e-11 42.6 14.5 7 7.0 0.0 10.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_3 PF07720.12 KNZ82009.1 - 1.5e-10 40.8 8.7 0.073 13.1 0.1 8.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ82009.1 - 2.9e-10 39.5 21.2 6.5 7.2 0.1 11.7 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ82009.1 - 1.3e-06 28.0 14.0 0.19 11.9 0.0 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_20 PF14561.6 KNZ82009.1 - 1.6e-06 28.3 17.8 7.3 7.0 0.1 9.5 3 2 2 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ82009.1 - 2.6e-06 27.5 13.2 8.4 7.4 0.1 9.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_5 PF12688.7 KNZ82009.1 - 3.9e-05 23.9 20.0 0.034 14.4 0.3 6.1 2 2 3 6 6 6 3 Tetratrico peptide repeat TPR_1 PF00515.28 KNZ82009.1 - 7.7e-05 22.3 13.6 6.3 6.8 0.0 9.4 12 0 0 12 12 12 1 Tetratricopeptide repeat DUF4404 PF14357.6 KNZ82009.1 - 0.00056 20.5 28.5 2.4 8.9 1.3 8.5 3 1 7 10 10 10 1 Domain of unknown function (DUF4404) PPR PF01535.20 KNZ82009.1 - 0.026 14.8 7.0 14 6.2 0.0 6.8 8 0 0 8 8 7 0 PPR repeat HV_small_capsid PF17086.5 KNZ82009.1 - 0.034 14.4 6.5 47 4.4 0.0 6.5 4 2 3 7 7 7 0 Small capsid protein of Herpesviridae DHDPS PF00701.22 KNZ82009.1 - 0.1 11.3 9.7 4.2 6.0 0.1 5.9 1 1 4 7 7 7 0 Dihydrodipicolinate synthetase family TPR_16 PF13432.6 KNZ82009.1 - 0.23 12.1 4.6 3.6 8.3 0.1 5.0 7 1 0 7 7 4 0 Tetratricopeptide repeat CDT1 PF08839.11 KNZ82009.1 - 0.27 11.5 13.7 2.6 8.3 0.9 4.3 2 2 1 4 4 4 0 DNA replication factor CDT1 like TPR_14 PF13428.6 KNZ82009.1 - 0.94 10.5 18.4 99 4.2 0.2 8.6 7 2 3 10 10 9 0 Tetratricopeptide repeat Barttin PF15462.6 KNZ82009.1 - 2.7 7.7 7.6 62 3.3 0.1 4.3 1 1 3 5 5 5 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) TetR_C_15 PF17918.1 KNZ82009.1 - 5.3 7.9 6.8 1.5e+02 3.2 0.2 5.1 4 2 2 6 6 6 0 Tetracyclin repressor-like, C-terminal domain Pho88 PF10032.9 KNZ82010.1 - 1.6e-28 99.2 0.1 2e-28 98.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TPR_10 PF13374.6 KNZ82011.1 - 1.1e-116 378.0 11.1 6.7e-09 35.4 0.2 15.4 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_12 PF13424.6 KNZ82011.1 - 3e-111 363.9 61.1 1.1e-13 51.3 2.4 11.5 4 2 9 13 13 13 12 Tetratricopeptide repeat TPR_MalT PF17874.1 KNZ82011.1 - 2.8e-21 76.3 54.2 1.7e-07 31.0 9.0 5.6 2 1 3 6 6 6 5 MalT-like TPR region TPR_19 PF14559.6 KNZ82011.1 - 8.7e-21 74.2 34.0 0.0022 18.4 0.0 11.4 4 3 8 13 13 13 8 Tetratricopeptide repeat TPR_17 PF13431.6 KNZ82011.1 - 1.6e-19 68.8 4.2 7 7.3 0.0 12.8 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ82011.1 - 5.3e-19 66.8 28.7 1.1 9.6 0.0 14.2 14 0 0 14 14 14 5 Tetratricopeptide repeat Patatin PF01734.22 KNZ82011.1 - 1.9e-11 44.5 0.0 7.5e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_20 PF14561.6 KNZ82011.1 - 2e-10 40.9 24.5 0.06 13.7 0.1 10.8 2 2 6 9 9 9 3 Tetratricopeptide repeat TPR_3 PF07720.12 KNZ82011.1 - 1.8e-09 37.4 14.6 0.29 11.2 0.1 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 KNZ82011.1 - 3.1e-09 36.6 11.1 0.77 10.6 0.1 11.1 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 KNZ82011.1 - 4e-09 35.9 32.8 2.7 8.3 0.1 12.7 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_5 PF12688.7 KNZ82011.1 - 7e-08 32.7 31.7 0.17 12.1 0.5 8.8 1 1 10 11 11 11 3 Tetratrico peptide repeat TPR_15 PF13429.6 KNZ82011.1 - 2.3e-07 30.3 19.1 1.4 8.0 0.0 9.1 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KNZ82011.1 - 1.1e-06 28.3 16.3 3.4 7.9 0.0 9.2 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 KNZ82011.1 - 1.9e-05 24.2 16.0 3.2 7.7 0.0 10.3 13 0 0 13 13 10 1 Tetratricopeptide repeat Ribo_biogen_C PF04034.13 KNZ82011.1 - 0.077 12.7 1.0 5.7 6.7 0.1 4.2 4 0 0 4 4 4 0 Ribosome biogenesis protein, C-terminal TPR_14 PF13428.6 KNZ82011.1 - 1.6 9.7 26.0 18 6.4 0.5 9.5 10 2 2 12 12 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ82011.1 - 2.5 8.8 11.1 18 6.0 0.0 6.3 6 3 1 7 7 6 0 Tetratricopeptide repeat DUF4054 PF13262.6 KNZ82011.1 - 2.7 8.1 7.1 1.2e+02 2.8 0.0 5.6 5 1 1 6 6 6 0 Protein of unknown function (DUF4054) Barttin PF15462.6 KNZ82011.1 - 7.8 6.2 16.2 6.6 6.4 0.1 5.1 2 1 1 5 5 5 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Glyco_hydro_12 PF01670.16 KNZ82012.1 - 1.8e-36 126.2 10.7 2e-36 126.0 10.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PPV_E2_C PF00511.17 KNZ82012.1 - 9.4 6.5 8.8 7.8 6.7 2.4 2.3 1 1 1 2 2 2 0 E2 (early) protein, C terminal zf-CCHC_3 PF13917.6 KNZ82013.1 - 1 9.4 7.0 2.5 8.1 7.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF5631 PF18645.1 KNZ82014.1 - 0.061 13.7 0.0 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5631) Zn_peptidase PF04228.13 KNZ82015.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Helitron_like_N PF14214.6 KNZ82017.1 - 7.4e-06 26.3 0.1 7.5e-05 23.0 0.0 2.2 1 1 0 2 2 2 1 Helitron helicase-like domain at N-terminus F-box-like PF12937.7 KNZ82018.1 - 8.1e-08 32.0 2.5 3e-07 30.2 0.5 2.8 2 1 0 2 2 2 1 F-box-like DUF4699 PF15770.5 KNZ82019.1 - 0.0023 17.8 0.4 0.0028 17.5 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4699) PIF1 PF05970.14 KNZ82021.1 - 7.8e-30 104.3 0.0 9.1e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ82021.1 - 0.0033 17.1 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal PX PF00787.24 KNZ82023.1 - 3.1e-26 91.6 0.0 4.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 PX domain FLYWCH PF04500.16 KNZ82024.1 - 0.013 15.5 0.3 0.027 14.6 0.3 1.5 1 0 0 1 1 1 0 FLYWCH zinc finger domain Y_phosphatase3 PF13350.6 KNZ82025.1 - 6e-50 170.4 0.0 6.8e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KNZ82025.1 - 6.8e-05 22.5 0.0 9.5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KNZ82025.1 - 0.002 18.0 0.0 0.0053 16.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 KNZ82025.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KNZ82025.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate Annexin PF00191.20 KNZ82026.1 - 3.1e-48 161.7 1.2 8.5e-13 48.2 0.1 4.3 4 0 0 4 4 4 4 Annexin Pkinase PF00069.25 KNZ82027.1 - 2.7e-09 36.8 0.0 4.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ82027.1 - 6.4e-05 23.0 0.7 0.00015 21.7 0.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KNZ82027.1 - 7.3e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KNZ82027.1 - 0.00018 21.0 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ82027.1 - 0.0065 15.8 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KNZ82027.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 2OG-FeII_Oxy PF03171.20 KNZ82028.1 - 1e-17 64.4 0.0 1.6e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KNZ82028.1 - 6.1e-09 36.7 0.5 1.1e-08 35.8 0.2 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF2484 PF10658.9 KNZ82029.1 - 0.14 12.5 3.3 0.29 11.5 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) F-box-like PF12937.7 KNZ82031.1 - 0.0006 19.7 0.2 0.0014 18.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ82031.1 - 0.032 14.1 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 F-box domain GspL_C PF12693.7 KNZ82032.1 - 0.18 11.6 0.1 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 GspL periplasmic domain LRR_6 PF13516.6 KNZ82032.1 - 0.57 10.4 3.9 34 4.8 0.2 4.1 3 0 0 3 3 3 0 Leucine Rich repeat DcpS_C PF11969.8 KNZ82033.1 - 8.9e-28 97.1 0.0 1.5e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KNZ82033.1 - 6.4e-24 84.8 0.0 1.1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal THB PF18362.1 KNZ82033.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Tri-helix bundle domain Sec2p PF06428.11 KNZ82038.1 - 1.5e-10 40.8 9.2 1.5e-10 40.8 9.2 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 KNZ82038.1 - 1.1 7.2 2.8 2.7 5.8 0.1 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mucin PF01456.17 KNZ82038.1 - 4.3 7.3 14.6 0.75 9.8 0.4 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF5401 PF17380.2 KNZ82038.1 - 5.8 4.9 13.5 8.9 4.3 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) PEP-utilisers_N PF05524.13 KNZ82038.1 - 7.2 6.8 8.2 5 7.3 2.6 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal APH PF01636.23 KNZ82039.1 - 1.3e-05 25.3 0.1 3.2e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ82039.1 - 0.00069 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF1679 PF07914.11 KNZ82039.1 - 0.012 14.5 0.0 0.039 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) CxC2 PF18803.1 KNZ82040.1 - 0.013 15.7 0.8 0.018 15.2 0.8 1.3 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases WD40 PF00400.32 KNZ82041.1 - 1.8e-26 91.8 8.7 1.7e-08 34.9 0.0 5.7 4 1 1 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ82041.1 - 1.2e-07 31.9 0.9 0.036 14.4 0.0 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KNZ82041.1 - 0.0096 15.3 0.8 0.12 11.6 0.0 2.7 2 1 1 3 3 3 1 WD40-like domain nos_propeller PF18764.1 KNZ82041.1 - 0.045 13.7 1.5 23 5.0 0.0 3.8 4 0 0 4 4 4 0 Nitrous oxide reductase propeller repeat PD40 PF07676.12 KNZ82041.1 - 0.051 13.5 0.0 25 4.9 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Terpene_synth_C PF03936.16 KNZ82043.1 - 1.3e-07 31.2 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Sensor PF13796.6 KNZ82045.1 - 2.5e-05 24.4 10.0 0.012 15.7 11.4 2.2 1 1 1 2 2 2 2 Putative sensor Cyt-b5 PF00173.28 KNZ82046.1 - 9.1e-11 41.8 0.1 1e-10 41.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M20 PF01546.28 KNZ82047.1 - 1.5e-07 31.3 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KNZ82047.1 - 8.3e-07 28.9 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Ricin_B_lectin PF00652.22 KNZ82048.1 - 9.1e-19 68.0 0.2 1.4e-18 67.4 0.2 1.2 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 KNZ82048.1 - 2.5e-16 60.1 1.4 5.9e-07 30.1 0.3 2.8 3 0 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like adh_short PF00106.25 KNZ82049.1 - 4.6e-18 65.4 0.0 3.3e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ82049.1 - 1.1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ82049.1 - 1.3e-05 25.2 0.0 0.00011 22.2 0.0 2.0 2 0 0 2 2 2 1 KR domain R3H PF01424.22 KNZ82050.1 - 2.1e-10 40.4 0.0 7.5e-10 38.7 0.0 2.0 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KNZ82050.1 - 8.4e-06 25.6 0.4 2.4e-05 24.2 0.4 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KNZ82050.1 - 0.00061 19.8 0.4 0.0036 17.4 0.4 2.4 1 0 0 1 1 1 1 G-patch domain Glyco_hydro_71 PF03659.14 KNZ82051.1 - 3e-106 355.4 2.0 4e-106 355.0 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WSC PF01822.19 KNZ82051.1 - 3.1e-18 65.7 7.8 3.1e-18 65.7 7.8 1.7 2 0 0 2 2 2 1 WSC domain Toxin_3 PF00537.18 KNZ82051.1 - 0.0096 16.1 1.6 0.0096 16.1 1.6 1.9 2 0 0 2 2 2 1 Scorpion toxin-like domain Tachylectin PF14517.6 KNZ82052.1 - 0.069 12.7 0.0 0.099 12.2 0.0 1.4 1 1 0 1 1 1 0 Tachylectin Ferritin_2 PF13668.6 KNZ82053.1 - 2.4e-33 115.2 0.2 3.7e-33 114.6 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain Glyoxalase PF00903.25 KNZ82054.1 - 2.5e-25 89.1 0.1 2.9e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KNZ82054.1 - 1.9e-07 31.8 0.0 2.4e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KNZ82054.1 - 2.1e-07 31.2 0.0 4.3e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 KNZ82054.1 - 0.00056 19.8 0.1 0.029 14.3 0.1 2.2 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KNZ82054.1 - 0.0033 17.5 0.0 0.005 17.0 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 KNZ82054.1 - 0.013 15.5 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 CppA N-terminal Sfi1 PF08457.10 KNZ82054.1 - 0.23 10.0 0.0 0.29 9.6 0.0 1.0 1 0 0 1 1 1 0 Sfi1 spindle body protein VPS13 PF16908.5 KNZ82056.1 - 0.007 16.2 2.6 0.0097 15.7 1.4 1.8 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal PLAC9 PF15205.6 KNZ82056.1 - 0.0092 16.4 0.2 0.051 14.0 0.1 2.3 1 1 1 2 2 2 1 Placenta-specific protein 9 DUF1759 PF03564.15 KNZ82056.1 - 0.02 14.9 3.3 0.57 10.1 0.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1759) DZR PF12773.7 KNZ82056.1 - 0.47 10.5 1.7 1 9.4 1.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon Apolipoprotein PF01442.18 KNZ82056.1 - 1.5 8.6 15.0 0.077 12.9 5.4 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.12 KNZ82056.1 - 2 8.9 10.8 25 5.4 0.1 5.0 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein YkpC PF17447.2 KNZ82057.1 - 0.25 12.2 2.0 22 6.2 0.3 2.7 2 0 0 2 2 2 0 Uncharacterized YkpC-like YkpC PF17447.2 KNZ82058.1 - 0.17 12.7 4.1 7.7 7.6 1.0 2.9 2 0 0 2 2 2 0 Uncharacterized YkpC-like Cytochrom_B558a PF05038.13 KNZ82058.1 - 1.7 8.2 4.3 1.4 8.4 1.0 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit LRR_8 PF13855.6 KNZ82060.1 - 2.8e-47 158.3 59.2 2.5e-11 43.1 2.3 10.9 5 3 8 13 13 13 11 Leucine rich repeat LRR_4 PF12799.7 KNZ82060.1 - 3.7e-44 148.0 65.9 4.9e-07 30.0 0.4 13.1 9 2 4 13 13 13 12 Leucine Rich repeats (2 copies) PP2C PF00481.21 KNZ82060.1 - 3.7e-39 134.9 0.0 6e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.20 KNZ82060.1 - 3.2e-19 69.3 0.0 5.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 KNZ82060.1 - 2.6e-07 30.3 19.2 0.4 10.2 0.3 5.9 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 KNZ82060.1 - 0.00024 21.2 53.7 11 7.0 0.1 16.2 16 3 1 17 17 17 2 Leucine Rich Repeat LRR_6 PF13516.6 KNZ82060.1 - 0.66 10.2 56.9 0.66 10.2 0.1 13.7 16 0 0 16 16 16 0 Leucine Rich repeat DUF4571 PF15137.6 KNZ82060.1 - 0.74 9.4 3.2 4.1 7.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4571) Toxin_32 PF08120.11 KNZ82060.1 - 7.2 6.5 5.6 2.7 7.9 0.4 2.6 3 0 0 3 3 3 0 Tamulustoxin family Mg_trans_NIPA PF05653.14 KNZ82061.1 - 8e-81 271.4 31.5 1.2e-80 270.8 31.5 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KNZ82061.1 - 2.2e-08 34.3 8.1 2.2e-08 34.3 8.1 3.9 3 1 0 3 3 3 2 EamA-like transporter family DUF1835 PF08874.10 KNZ82061.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) Lsr2 PF11774.8 KNZ82061.1 - 0.97 9.6 2.8 8.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Lsr2 Tmemb_161AB PF10268.9 KNZ82061.1 - 1.1 7.8 12.1 0.043 12.5 6.1 1.5 2 0 0 2 2 2 0 Predicted transmembrane protein 161AB Mannosidase_ig PF17786.1 KNZ82062.1 - 9.3e-12 45.4 1.9 1.5e-11 44.8 0.1 2.2 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KNZ82062.1 - 3.4e-11 42.7 0.0 1e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KNZ82062.1 - 0.068 13.9 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Barwin PF00967.17 KNZ82064.1 - 0.0058 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.18 KNZ82064.1 - 0.014 15.7 0.0 0.023 14.9 0.0 1.6 1 1 0 1 1 1 0 Lytic transglycolase SH3_9 PF14604.6 KNZ82065.1 - 6.3e-25 86.8 1.1 2.1e-13 49.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 KNZ82065.1 - 5.1e-22 77.3 0.1 3.2e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KNZ82065.1 - 3.6e-21 74.5 0.1 5.6e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 KNZ82065.1 - 4.7e-13 49.2 0.5 4.7e-13 49.2 0.5 2.6 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 KNZ82065.1 - 1.2e-10 41.1 4.4 1.9e-10 40.4 4.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 KNZ82065.1 - 0.0075 16.5 1.2 0.014 15.6 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain FYVE PF01363.21 KNZ82065.1 - 0.097 12.8 1.0 0.22 11.7 1.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Phage_TAC_4 PF08748.11 KNZ82065.1 - 2.2 8.6 7.7 0.59 10.4 4.0 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone CAF1 PF04857.20 KNZ82066.1 - 8.5e-19 67.9 0.1 4.6e-11 42.4 0.0 2.4 1 1 1 2 2 2 2 CAF1 family ribonuclease RNase_H_2 PF13482.6 KNZ82066.1 - 0.035 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 RNase_H superfamily EBP PF05241.12 KNZ82067.1 - 4.3e-67 225.0 6.6 4.9e-67 224.8 6.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein 7tm_1 PF00001.21 KNZ82067.1 - 0.047 13.0 1.0 0.058 12.7 0.1 1.7 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) FixQ PF05545.11 KNZ82067.1 - 0.28 11.2 0.2 0.28 11.2 0.2 3.2 3 1 1 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Fungal_trans PF04082.18 KNZ82068.1 - 7e-16 58.1 0.1 1.2e-15 57.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.12 KNZ82068.1 - 0.078 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF2688 PF10892.8 KNZ82068.1 - 0.1 12.1 3.8 0.47 9.9 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Fungal_trans PF04082.18 KNZ82069.1 - 2.3e-12 46.5 0.1 4.2e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHC2_SAM_assoc PF16616.5 KNZ82069.1 - 0.02 15.7 0.1 0.04 14.7 0.1 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Zn_clus PF00172.18 KNZ82069.1 - 2.1 8.5 5.6 3.9 7.7 5.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CMAS PF02353.20 KNZ82070.1 - 3.6e-60 203.6 0.0 5.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 KNZ82070.1 - 4.1e-09 37.0 0.0 8.2e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ82070.1 - 7e-06 26.6 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KNZ82070.1 - 7.8e-05 22.5 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_12 PF08242.12 KNZ82070.1 - 0.00014 22.5 0.0 0.0003 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ82070.1 - 0.0003 20.6 0.0 0.00055 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ82070.1 - 0.00055 19.5 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KNZ82070.1 - 0.00076 19.3 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 KNZ82070.1 - 0.00088 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KNZ82070.1 - 0.001 20.1 0.0 0.0024 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KNZ82070.1 - 0.0029 17.4 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KNZ82070.1 - 0.0034 17.1 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 KNZ82070.1 - 0.049 13.4 0.1 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) HetR_C PF18460.1 KNZ82070.1 - 0.082 12.8 1.1 0.21 11.5 0.3 2.0 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain RrnaAD PF00398.20 KNZ82070.1 - 0.19 10.8 0.1 0.58 9.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Rif1_N PF12231.8 KNZ82071.1 - 0.11 11.4 1.9 1.3 8.0 1.9 2.4 1 1 0 1 1 1 0 Rap1-interacting factor 1 N terminal NTP_transf_9 PF04248.12 KNZ82072.1 - 3.7e-31 106.9 1.8 3.7e-31 106.9 1.8 1.9 2 1 1 3 3 3 1 Domain of unknown function (DUF427) PRiA4_ORF3 PF07929.11 KNZ82072.1 - 1.7e-09 37.6 0.6 2.7e-08 33.7 0.6 2.2 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein GPI-anchored PF10342.9 KNZ82073.1 - 2.5e-05 24.9 0.0 3.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AMP-binding PF00501.28 KNZ82076.1 - 7.1e-23 80.9 0.0 9.2e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KNZ82077.1 - 1.6e-28 99.5 0.0 1.9e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ82077.1 - 5.3e-12 46.5 0.0 1.2e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 KNZ82078.1 - 4.1e-41 140.9 0.1 1.4e-20 73.3 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ82078.1 - 8.3e-12 45.9 0.2 1.9e-11 44.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1118 PF06549.12 KNZ82078.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) GARP PF16731.5 KNZ82079.1 - 0.061 13.0 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma UQ_con PF00179.26 KNZ82081.1 - 1.1e-42 145.0 0.0 1.4e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 KNZ82081.1 - 1.1e-19 70.0 0.1 2e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 KNZ82081.1 - 6e-05 22.9 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain Prok-E2_B PF14461.6 KNZ82081.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Peptidase_S10 PF00450.22 KNZ82082.1 - 2.2e-90 304.1 0.5 2.7e-90 303.8 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Tannase PF07519.11 KNZ82082.1 - 0.042 12.7 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase DFP PF04127.15 KNZ82083.1 - 0.023 14.5 1.8 0.042 13.7 1.8 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.16 KNZ82084.1 - 2e-25 89.5 78.5 5.5e-23 81.4 41.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EB1 PF03271.17 KNZ82085.1 - 1.9e-16 60.0 3.6 3.6e-16 59.1 3.6 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 KNZ82085.1 - 7.9e-07 29.2 0.2 1.3e-06 28.6 0.2 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 KNZ82085.1 - 0.0012 17.4 0.0 0.0015 17.1 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like HXXSHH PF07586.11 KNZ82085.1 - 0.19 11.2 0.1 0.25 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) SUIM_assoc PF16619.5 KNZ82085.1 - 0.24 11.5 1.7 0.44 10.6 1.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_S10 PF00450.22 KNZ82087.1 - 6.5e-94 315.7 3.9 7.7e-94 315.5 3.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ank_2 PF12796.7 KNZ82092.1 - 4.3e-86 283.6 18.8 2.4e-20 72.9 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KNZ82092.1 - 2.2e-65 215.8 14.5 5e-12 45.8 0.3 7.1 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ82092.1 - 1.6e-64 213.5 2.2 1.1e-10 41.8 0.0 8.3 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KNZ82092.1 - 1.4e-63 208.7 1.1 2.1e-06 27.9 0.0 9.2 9 0 0 9 9 9 9 Ankyrin repeat Ank_3 PF13606.6 KNZ82092.1 - 2.3e-52 168.8 0.0 3.5e-05 23.8 0.0 9.0 9 0 0 9 9 9 8 Ankyrin repeat DUF3581 PF12119.8 KNZ82092.1 - 0.00023 20.6 5.9 0.11 11.9 0.0 5.0 1 1 3 5 5 5 1 Protein of unknown function (DUF3581) DUF4115 PF13464.6 KNZ82092.1 - 0.001 19.2 7.0 19 5.5 0.0 6.1 4 3 3 7 7 7 0 Domain of unknown function (DUF4115) VWA_3_C PF18571.1 KNZ82092.1 - 0.0021 17.9 9.4 2.5 8.1 0.2 5.5 5 0 0 5 5 5 2 von Willebrand factor type A C-terminal domain AMNp_N PF10423.9 KNZ82092.1 - 0.0093 15.6 0.1 7.7 6.1 0.0 3.9 4 1 1 5 5 5 1 Bacterial AMP nucleoside phosphorylase N-terminus MCC-bdg_PDZ PF10506.9 KNZ82092.1 - 0.015 15.3 0.0 8.9 6.4 0.0 4.6 6 0 0 6 6 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome cpYpsA PF12694.7 KNZ82092.1 - 0.045 13.6 1.9 8.3 6.2 0.1 3.9 2 2 1 3 3 3 0 Circularly permutated YpsA SLOG family EccE PF11203.8 KNZ82092.1 - 0.054 13.8 0.3 26 5.2 0.1 3.0 2 1 1 3 3 3 0 Putative type VII ESX secretion system translocon, EccE rve PF00665.26 KNZ82092.1 - 0.093 12.9 0.2 5.7 7.2 0.1 2.5 2 1 0 2 2 2 0 Integrase core domain DUF2989 PF11207.8 KNZ82092.1 - 0.1 12.4 0.6 7.7 6.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) MG4 PF17789.1 KNZ82092.1 - 0.69 10.1 2.6 14 5.9 0.2 4.0 4 1 0 4 4 4 0 Macroglobulin domain MG4 Pput2613-deam PF14427.6 KNZ82092.1 - 5.1 7.0 10.8 30 4.5 0.0 5.4 4 2 2 6 6 6 0 Pput_2613-like deaminase Ank_2 PF12796.7 KNZ82093.1 - 4.1e-67 222.8 21.8 4.7e-18 65.5 0.6 5.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 KNZ82093.1 - 3.9e-58 191.5 13.6 5.4e-06 26.6 0.0 10.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.6 KNZ82093.1 - 2.4e-54 180.7 5.2 7.2e-10 38.9 0.1 8.3 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 KNZ82093.1 - 7.3e-54 179.5 7.8 3.4e-11 43.4 0.0 8.4 2 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KNZ82093.1 - 3.2e-48 156.1 3.4 0.00016 21.9 0.0 10.8 10 1 0 10 10 10 8 Ankyrin repeat KH_4 PF13083.6 KNZ82093.1 - 0.036 13.9 1.6 8.3 6.4 0.1 5.1 4 1 1 5 5 5 0 KH domain Glyco_hydro_32C PF08244.12 KNZ82093.1 - 0.098 12.7 2.7 3.9 7.5 1.9 3.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal VWA_3_C PF18571.1 KNZ82093.1 - 0.27 11.1 9.8 1.2 9.1 0.1 5.4 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain DUF5300 PF17224.3 KNZ82093.1 - 5.3 7.4 10.4 0.78 10.0 0.3 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF5300) zf_C2H2_ZHX PF18387.1 KNZ82093.1 - 8.9 6.0 7.2 2.1 8.1 0.2 3.5 4 0 0 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain Methyltransf_23 PF13489.6 KNZ82095.1 - 4.1e-17 62.5 0.0 5.7e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KNZ82095.1 - 3.1e-14 53.5 0.0 7.8e-14 52.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KNZ82095.1 - 6.4e-14 52.4 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KNZ82095.1 - 8.3e-12 45.1 0.0 1.5e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ82095.1 - 2.5e-11 44.2 0.0 5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KNZ82095.1 - 3.5e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 KNZ82095.1 - 0.00014 21.2 0.0 0.00056 19.3 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KNZ82095.1 - 0.0002 21.5 0.0 0.00029 21.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 KNZ82095.1 - 0.00092 18.8 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KNZ82095.1 - 0.0024 17.3 0.0 0.0033 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 KNZ82095.1 - 0.021 14.3 0.0 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.12 KNZ82095.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 KNZ82095.1 - 0.024 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 KNZ82095.1 - 0.053 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 KNZ82095.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KNZ82095.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AXE1 PF05448.12 KNZ82096.1 - 0.0064 15.2 0.1 0.011 14.4 0.1 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF463 PF04317.12 KNZ82096.1 - 0.057 12.3 0.4 0.083 11.8 0.4 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Pkinase_fungal PF17667.1 KNZ82097.1 - 1.2e-53 182.4 0.4 1.7e-53 181.9 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KNZ82097.1 - 0.026 13.9 0.3 0.058 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein kinase domain TAtT PF16811.5 KNZ82097.1 - 0.072 12.4 0.4 0.12 11.7 0.4 1.3 1 0 0 1 1 1 0 TRAP transporter T-component Integrase_H2C2 PF17921.1 KNZ82099.1 - 0.13 12.4 2.3 0.49 10.5 0.4 2.7 2 0 0 2 2 2 0 Integrase zinc binding domain MFS_1 PF07690.16 KNZ82101.1 - 3.2e-32 111.8 37.0 3.2e-32 111.8 37.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SIT PF15330.6 KNZ82101.1 - 0.11 12.9 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Sid-5 PF17204.3 KNZ82101.1 - 0.12 12.6 0.4 0.3 11.3 0.4 1.6 1 0 0 1 1 1 0 Sid-5 family Sigma_reg_N PF13800.6 KNZ82101.1 - 0.24 11.7 1.5 0.92 9.8 1.5 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5392 PF17370.2 KNZ82101.1 - 1.2 9.2 4.0 1.8 8.7 1.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5392) DctQ PF04290.12 KNZ82102.1 - 0.23 11.4 4.5 0.067 13.1 1.5 1.6 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Asp_protease_2 PF13650.6 KNZ82104.1 - 0.00035 21.1 0.0 0.00058 20.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ82104.1 - 0.0021 18.6 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Pho88 PF10032.9 KNZ82104.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Phosphate transport (Pho88) RNase_H PF00075.24 KNZ82106.1 - 5.7e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 RNase H Zn_Tnp_IS1595 PF12760.7 KNZ82106.1 - 0.0048 16.8 1.7 0.012 15.6 0.2 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-RVT PF13966.6 KNZ82106.1 - 0.011 16.5 2.5 0.048 14.4 1.0 2.6 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase Tachylectin PF14517.6 KNZ82108.1 - 0.059 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Tachylectin Pkinase_fungal PF17667.1 KNZ82110.1 - 1.1e-32 113.4 0.8 1.6e-32 112.8 0.8 1.2 1 0 0 1 1 1 1 Fungal protein kinase TAtT PF16811.5 KNZ82110.1 - 0.034 13.4 0.4 0.054 12.8 0.4 1.2 1 0 0 1 1 1 0 TRAP transporter T-component Chromo PF00385.24 KNZ82112.1 - 0.027 14.4 0.1 0.043 13.7 0.1 1.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain tRNA_lig_CPD PF08302.11 KNZ82112.1 - 0.099 12.1 0.0 0.27 10.6 0.0 1.6 2 0 0 2 2 2 0 Fungal tRNA ligase phosphodiesterase domain GMC_oxred_C PF05199.13 KNZ82114.1 - 8.4e-09 36.1 0.0 2.9e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KNZ82114.1 - 2.3e-05 23.9 0.0 9.7e-05 21.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_3 PF01494.19 KNZ82114.1 - 0.0052 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Ribonuc_L-PSP PF01042.21 KNZ82114.1 - 0.093 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease L-PSP ApbA PF02558.16 KNZ82114.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KNZ82114.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AUDH_Cupin PF18637.1 KNZ82115.1 - 1.6e-60 203.7 0.7 3.9e-60 202.4 0.7 1.6 1 0 0 1 1 1 1 Aldos-2-ulose dehydratase/isomerase (AUDH) Cupin domain PBP3 PF18056.1 KNZ82115.1 - 1.7e-28 98.9 0.0 3.7e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Penicillin Binding Protein 3 Domain VCBS PF13517.6 KNZ82115.1 - 0.22 12.1 5.1 2.9 8.6 0.5 3.9 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BTB PF00651.31 KNZ82116.1 - 0.0035 17.6 0.0 0.0067 16.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.22 KNZ82117.1 - 1.4e-63 215.3 0.0 1.5e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helitron_like_N PF14214.6 KNZ82120.1 - 2.2e-20 73.7 0.3 3e-20 73.3 0.3 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 KNZ82122.1 - 2.9e-88 296.5 0.0 3.3e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ82122.1 - 0.011 15.4 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal AAA_30 PF13604.6 KNZ82122.1 - 0.016 14.9 0.1 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain ChaC PF04752.12 KNZ82124.1 - 3.5e-38 131.4 0.1 3.5e-33 115.2 0.0 2.0 1 1 1 2 2 2 2 ChaC-like protein Aminotran_4 PF01063.19 KNZ82125.1 - 4e-28 98.8 0.0 5e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV F-box-like PF12937.7 KNZ82126.1 - 1.3e-07 31.3 0.3 3.4e-07 30.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KNZ82126.1 - 0.00014 21.6 0.1 0.00033 20.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain YL1 PF05764.13 KNZ82129.1 - 5.8e-36 124.8 17.5 5.8e-36 124.8 17.5 2.1 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 KNZ82129.1 - 4.3e-14 52.0 0.4 7.3e-14 51.2 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain L51_S25_CI-B8 PF05047.16 KNZ82130.1 - 5.6e-07 29.4 0.1 1.1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_33 PF10017.9 KNZ82130.1 - 0.19 10.9 0.3 0.25 10.5 0.3 1.1 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Pkinase PF00069.25 KNZ82131.1 - 4.9e-11 42.5 0.0 5.1e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ82131.1 - 7.3e-11 41.8 0.0 2.1e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase GET2 PF08690.10 KNZ82132.1 - 0.00034 20.4 3.2 0.14 11.8 0.2 2.3 1 1 1 2 2 2 2 GET complex subunit GET2 PhzC-PhzF PF02567.16 KNZ82133.1 - 9.4e-49 166.4 0.0 1.1e-48 166.2 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Ppx-GppA PF02541.16 KNZ82133.1 - 0.11 11.9 0.3 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family OTT_1508_deam PF14441.6 KNZ82134.1 - 5.7e-07 29.4 0.1 1.2e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase DPBB_1 PF03330.18 KNZ82136.1 - 4.3e-11 42.9 0.2 2.1e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 Lytic transglycolase Orbi_VP1 PF05788.12 KNZ82136.1 - 0.0012 16.6 0.1 0.0015 16.2 0.1 1.0 1 0 0 1 1 1 1 Orbivirus RNA-dependent RNA polymerase (VP1) Barwin PF00967.17 KNZ82136.1 - 0.021 14.7 1.0 0.047 13.6 0.2 1.8 1 1 1 2 2 2 0 Barwin family DAO PF01266.24 KNZ82137.1 - 1.4e-18 67.6 0.3 1.7e-18 67.3 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FeoB_associated PF12669.7 KNZ82137.1 - 0.99 9.9 4.7 2 8.9 4.7 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein MutS_V PF00488.21 KNZ82138.1 - 2.1e-56 190.9 0.0 4.4e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KNZ82138.1 - 1.7e-31 109.9 1.4 1.7e-31 109.9 1.4 1.9 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KNZ82138.1 - 0.00033 20.9 0.1 0.005 17.1 0.0 2.8 2 1 0 2 2 2 1 MutS domain II AAA_27 PF13514.6 KNZ82138.1 - 0.022 14.4 0.0 0.096 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MutS_IV PF05190.18 KNZ82138.1 - 0.028 14.8 0.0 0.092 13.1 0.0 1.9 1 0 0 1 1 1 0 MutS family domain IV Epsilon_antitox PF08998.11 KNZ82138.1 - 0.064 13.5 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 Bacterial epsilon antitoxin DIOX_N PF14226.6 KNZ82140.1 - 6.5e-16 59.1 0.0 7.4e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Exo_endo_phos PF03372.23 KNZ82142.1 - 0.016 14.7 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF4886 PF16227.5 KNZ82142.1 - 0.082 12.1 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) Herpes_Helicase PF02689.14 KNZ82143.1 - 0.0015 16.5 0.0 0.0016 16.4 0.0 1.0 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 KNZ82144.1 - 2.5e-22 79.5 0.0 3.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase TFIIA PF03153.13 KNZ82145.1 - 5.8 6.8 15.9 7.8 6.4 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 KNZ82146.1 - 1 7.5 19.1 1.8 6.6 19.1 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 KNZ82146.1 - 5.1 5.3 13.4 7.3 4.7 13.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KNZ82146.1 - 7.5 5.9 20.2 16 4.8 20.2 1.5 1 0 0 1 1 1 0 SDA1 Solute_trans_a PF03619.16 KNZ82147.1 - 4e-70 236.4 15.1 4.8e-70 236.1 15.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha UPF0697 PF15117.6 KNZ82147.1 - 0.26 11.4 0.8 0.66 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 Glycos_transf_4 PF00953.21 KNZ82147.1 - 1.5 8.8 9.1 21 5.0 9.4 2.8 1 1 0 1 1 1 0 Glycosyl transferase family 4 DUF1275 PF06912.11 KNZ82148.1 - 8e-31 107.5 11.8 1e-30 107.1 11.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2231 PF09990.9 KNZ82148.1 - 0.02 15.3 0.4 0.1 13.0 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Med9 PF07544.13 KNZ82149.1 - 0.00016 21.7 0.1 0.00025 21.1 0.1 1.4 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CENP-T_C PF15511.6 KNZ82149.1 - 0.04 14.1 0.0 0.046 13.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF3500 PF12006.8 KNZ82149.1 - 0.073 12.5 0.1 0.083 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF5586 PF17824.1 KNZ82149.1 - 0.083 12.0 0.1 0.098 11.7 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5586) RNA_pol_Rpb1_1 PF04997.12 KNZ82150.1 - 1.2e-109 366.5 0.0 1.9e-109 365.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 KNZ82150.1 - 1.4e-105 352.5 0.0 2e-105 352.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KNZ82150.1 - 1.2e-73 246.8 0.0 2.3e-73 245.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KNZ82150.1 - 1.1e-67 227.6 0.0 2.3e-67 226.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 KNZ82150.1 - 6.8e-51 172.3 0.0 4e-50 169.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 KNZ82150.1 - 5.8e-48 162.3 1.5 1.3e-47 161.2 1.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 KNZ82150.1 - 2.1e-35 120.9 0.0 4.4e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KNZ82150.1 - 6.5e-09 35.7 197.2 0.026 14.9 2.6 14.0 6 3 3 13 13 13 10 RNA polymerase Rpb1 C-terminal repeat RT_RNaseH PF17917.1 KNZ82151.1 - 1.8e-08 34.6 0.1 3.7e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 KNZ82151.1 - 2.6e-08 33.8 0.1 4.6e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DDE_Tnp_IS1595 PF12762.7 KNZ82151.1 - 0.13 12.3 0.4 0.45 10.5 0.4 1.9 1 0 0 1 1 1 0 ISXO2-like transposase domain RecO_C PF02565.15 KNZ82153.1 - 0.12 12.1 3.0 9.8 6.0 0.0 3.1 2 1 1 3 3 3 0 Recombination protein O C terminal Ribosomal_S30 PF04758.14 KNZ82155.1 - 1.4e-28 98.8 6.3 1.5e-28 98.7 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Fib_alpha PF08702.10 KNZ82156.1 - 0.83 9.8 4.9 1.3 9.2 1.1 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 KNZ82156.1 - 1.3 9.3 12.0 7.5 6.9 0.8 4.4 4 0 0 4 4 4 0 Homeobox associated leucine zipper APH PF01636.23 KNZ82157.1 - 9.4e-12 45.4 0.0 1.3e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ82157.1 - 0.00033 20.3 0.1 0.00053 19.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 KNZ82157.1 - 0.011 15.3 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HsbA PF12296.8 KNZ82157.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Pyr_redox_2 PF07992.14 KNZ82158.1 - 3e-67 226.9 3.5 5.1e-67 226.2 3.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KNZ82158.1 - 6.1e-45 152.0 1.9 1.4e-43 147.6 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KNZ82158.1 - 6.4e-21 74.7 6.9 5e-18 65.5 1.1 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KNZ82158.1 - 2.7e-11 43.5 0.1 2.7e-11 43.5 0.1 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 KNZ82158.1 - 4.5e-11 42.5 4.9 4.4e-10 39.2 0.1 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KNZ82158.1 - 3.5e-08 33.5 4.3 0.0001 22.4 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KNZ82158.1 - 4.4e-08 32.8 4.4 8.5e-05 21.9 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KNZ82158.1 - 1.5e-07 30.8 2.3 1.5e-07 30.8 2.3 3.3 2 1 1 3 3 3 1 FAD binding domain HI0933_like PF03486.14 KNZ82158.1 - 8.2e-07 28.1 12.2 0.00018 20.4 0.9 3.9 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 KNZ82158.1 - 1.1e-05 24.8 0.3 0.11 11.6 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 KNZ82158.1 - 3.5e-05 23.2 5.6 0.022 14.0 0.3 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 KNZ82158.1 - 7.5e-05 22.1 11.7 0.01 15.1 1.0 3.8 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 KNZ82158.1 - 0.00027 20.7 13.3 0.16 11.5 0.2 3.9 4 1 0 5 5 5 2 FAD dependent oxidoreductase Thi4 PF01946.17 KNZ82158.1 - 0.00067 19.0 3.0 0.0012 18.1 0.1 2.3 2 0 0 2 2 2 1 Thi4 family THF_DHG_CYH_C PF02882.19 KNZ82158.1 - 0.0087 15.4 0.1 0.045 13.1 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KNZ82158.1 - 3.3 8.2 6.6 9.1 6.8 0.9 3.4 3 1 0 3 3 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 KNZ82158.1 - 3.8 6.5 8.7 1.5 7.8 0.6 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Pkinase PF00069.25 KNZ82159.1 - 4.5e-36 124.6 0.0 9.8e-36 123.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ82159.1 - 2.6e-15 56.4 0.0 3.7e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KNZ82159.1 - 0.00022 21.2 0.4 0.00042 20.3 0.4 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KNZ82159.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KNZ82159.1 - 0.061 12.6 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KNZ82159.1 - 0.21 10.3 0.0 0.35 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TolA_bind_tri PF16331.5 KNZ82160.1 - 0.0067 16.5 3.2 2.9 8.0 2.1 2.4 2 0 0 2 2 2 2 TolA binding protein trimerisation Lzipper-MIP1 PF14389.6 KNZ82160.1 - 0.011 16.0 1.2 0.042 14.1 0.7 2.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Mito_fiss_reg PF05308.11 KNZ82160.1 - 0.014 15.5 0.2 0.056 13.5 0.0 1.7 1 1 0 1 1 1 0 Mitochondrial fission regulator IFP_35_N PF07334.13 KNZ82160.1 - 0.027 14.6 1.8 0.027 14.6 1.8 2.0 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Macoilin PF09726.9 KNZ82160.1 - 0.035 12.7 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Macoilin family Cys_rich_KTR PF14205.6 KNZ82160.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR Profilin PF00235.19 KNZ82161.1 - 1.5e-36 125.4 0.1 3e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Profilin zf-TFIIIC PF12660.7 KNZ82161.1 - 1.8e-16 59.9 1.5 3.7e-16 58.9 0.3 2.1 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 KNZ82161.1 - 6.6e-13 49.0 0.5 1.4e-12 47.9 0.5 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term PhoLip_ATPase_C PF16212.5 KNZ82162.1 - 1.2e-71 241.4 30.6 1.2e-71 241.4 30.6 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KNZ82162.1 - 1.4e-21 75.9 0.2 3.7e-21 74.6 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KNZ82162.1 - 1.3e-13 50.8 0.0 3.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KNZ82162.1 - 2.4e-10 41.1 0.1 1.3e-06 28.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KNZ82162.1 - 1.4e-05 24.7 0.1 1.4e-05 24.7 0.1 3.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KNZ82162.1 - 0.00058 19.7 0.1 0.012 15.3 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 KNZ82163.1 - 5.9e-23 81.2 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KNZ82163.1 - 8.1e-10 38.7 10.8 1.9e-09 37.5 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 KNZ82164.1 - 2.9e-05 23.9 0.2 2.9e-05 23.9 0.2 2.2 2 1 0 2 2 2 1 F-box-like LRR_6 PF13516.6 KNZ82164.1 - 0.24 11.5 2.6 10 6.5 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Mito_carr PF00153.27 KNZ82165.1 - 2.5e-52 174.7 0.3 1.8e-17 63.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Abhydrolase_6 PF12697.7 KNZ82166.1 - 3.3e-12 47.5 2.9 4.5e-12 47.0 2.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KNZ82166.1 - 9.3e-10 38.2 0.1 1.2e-08 34.5 0.1 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KNZ82166.1 - 4.4e-08 33.1 0.0 1e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KNZ82166.1 - 1.8e-06 28.0 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 KNZ82166.1 - 0.0012 18.8 0.2 0.0021 17.9 0.2 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 KNZ82166.1 - 0.0019 18.3 0.0 0.0045 17.1 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 KNZ82166.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Peptidase_S15 PF02129.18 KNZ82166.1 - 0.013 15.1 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 KNZ82166.1 - 0.084 12.4 0.0 1.2 8.6 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family LIDHydrolase PF10230.9 KNZ82166.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase PF00151.19 KNZ82166.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase DUF818 PF05677.12 KNZ82166.1 - 0.26 10.2 0.0 0.37 9.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) RVT_1 PF00078.27 KNZ82167.1 - 1.6e-05 24.5 0.1 1.8e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HsbA PF12296.8 KNZ82168.1 - 2.6e-13 50.5 6.1 2.6e-13 50.5 6.1 1.6 2 0 0 2 2 2 1 Hydrophobic surface binding protein A tRNA-synt_2d PF01409.20 KNZ82170.1 - 2.8e-29 102.3 0.1 3.6e-26 92.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KNZ82170.1 - 3.6e-14 52.8 0.0 7.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 KNZ82170.1 - 0.00018 21.4 0.1 0.00034 20.5 0.1 1.5 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 KNZ82170.1 - 0.01 15.3 0.0 0.042 13.3 0.1 1.8 2 0 0 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain Pil1 PF13805.6 KNZ82172.1 - 1.2e-17 64.3 1.3 1.9e-17 63.6 1.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Fez1 PF06818.15 KNZ82172.1 - 0.37 11.2 2.1 0.81 10.1 2.1 1.5 1 0 0 1 1 1 0 Fez1 Synaptobrevin PF00957.21 KNZ82172.1 - 2.5 8.0 3.3 3.7 7.4 0.3 2.4 2 0 0 2 2 2 0 Synaptobrevin AA_permease PF00324.21 KNZ82173.1 - 2.5e-135 451.8 43.8 3e-135 451.5 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KNZ82173.1 - 3e-36 125.2 46.1 4.1e-36 124.7 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 KNZ82175.1 - 5.4e-58 196.3 0.2 6.1e-58 196.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KNZ82175.1 - 1.8e-52 177.7 0.2 2.1e-52 177.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KNZ82175.1 - 2.8e-08 33.9 0.3 4.5e-08 33.2 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KNZ82175.1 - 0.016 15.1 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.6 KNZ82175.1 - 0.16 12.6 0.3 0.5 11.0 0.2 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain 2OG-FeII_Oxy_3 PF13640.6 KNZ82176.1 - 2.2e-12 47.7 0.0 3.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily BPS PF08947.10 KNZ82176.1 - 0.0097 15.7 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 BPS (Between PH and SH2) PhyH PF05721.13 KNZ82176.1 - 0.056 13.7 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) THOC7 PF05615.13 KNZ82178.1 - 0.0039 17.5 0.2 0.0092 16.3 0.2 1.5 1 0 0 1 1 1 1 Tho complex subunit 7 Prefoldin PF02996.17 KNZ82178.1 - 0.044 13.7 0.2 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit Cep57_CLD_2 PF14197.6 KNZ82178.1 - 0.15 12.2 2.6 0.26 11.4 1.7 1.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 LysM PF01476.20 KNZ82179.1 - 3.1e-19 68.7 0.0 6.2e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 LysM domain DUF4772 PF15997.5 KNZ82179.1 - 0.082 13.5 0.0 0.098 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) Pkinase PF00069.25 KNZ82181.1 - 2.1e-21 76.5 0.0 1.3e-20 73.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ82181.1 - 4.3e-09 36.0 0.0 2.3e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KNZ82181.1 - 0.057 12.2 0.2 0.079 11.7 0.2 1.2 1 0 0 1 1 1 0 Fungal protein kinase KSHV_K1 PF11049.8 KNZ82181.1 - 0.085 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus p450 PF00067.22 KNZ82183.1 - 1.3e-71 241.8 0.0 1.6e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pox_D5 PF03288.16 KNZ82183.1 - 0.15 12.6 0.0 6.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Poxvirus D5 protein-like Ribosomal_L37 PF08561.10 KNZ82184.1 - 0.082 13.4 0.1 0.092 13.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 RT_RNaseH_2 PF17919.1 KNZ82185.1 - 0.0011 19.0 0.0 0.016 15.3 0.0 2.2 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase p450 PF00067.22 KNZ82186.1 - 1.1e-68 232.1 0.0 1.4e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Helitron_like_N PF14214.6 KNZ82187.1 - 1.8e-24 87.0 0.0 2.2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Inovirus_Gp2 PF11726.8 KNZ82187.1 - 0.019 14.9 0.1 0.022 14.7 0.1 1.1 1 0 0 1 1 1 0 Inovirus Gp2 PIF1 PF05970.14 KNZ82188.1 - 2.5e-40 138.8 0.1 8.5e-22 77.8 0.0 2.0 1 1 0 2 2 2 2 PIF1-like helicase ResIII PF04851.15 KNZ82188.1 - 0.0076 16.3 0.0 0.015 15.3 0.0 1.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 KNZ82188.1 - 0.027 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 KNZ82188.1 - 0.034 13.9 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KNZ82188.1 - 0.1 12.9 0.1 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 KNZ82188.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2791 PF10923.8 KNZ82188.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) TFIIA PF03153.13 KNZ82190.1 - 3.4e-54 185.4 0.0 2.5e-35 123.3 0.0 2.4 2 1 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 KNZ82190.1 - 6e-13 49.3 1.8 1.5e-12 48.0 1.8 1.8 1 1 0 1 1 1 1 Gti1/Pac2 family Gti1_Pac2 PF09729.9 KNZ82191.1 - 1.3e-29 103.6 0.9 1.8e-25 90.1 0.3 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_1e PF01406.19 KNZ82192.1 - 1.1e-126 422.3 0.1 1.1e-126 422.3 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KNZ82192.1 - 3.1e-07 29.5 0.3 0.00074 18.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KNZ82192.1 - 1e-06 27.4 1.5 0.0037 15.6 0.0 3.3 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 KNZ82192.1 - 2.1e-05 24.9 1.2 5.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 DALR domain GAF PF01590.26 KNZ82193.1 - 0.003 18.2 0.0 0.004 17.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 KNZ82193.1 - 0.033 14.5 0.0 0.065 13.5 0.0 1.5 2 0 0 2 2 2 0 GAF domain GLTP PF08718.11 KNZ82194.1 - 1.5e-47 161.6 0.1 1.9e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) SET PF00856.28 KNZ82195.1 - 3e-17 63.5 0.0 7.3e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 KNZ82195.1 - 4.1e-14 53.4 0.1 8.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding LysM PF01476.20 KNZ82195.1 - 6.8e-08 32.4 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 LysM domain BEN PF10523.9 KNZ82195.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 BEN domain CRAL_TRIO PF00650.20 KNZ82196.1 - 2.1e-14 53.6 0.0 3.4e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Metallophos PF00149.28 KNZ82197.1 - 6e-36 124.9 0.5 8.1e-36 124.4 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KNZ82197.1 - 0.03 14.8 0.6 0.072 13.5 0.6 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain zf-C2H2 PF00096.26 KNZ82198.1 - 1.5e-08 34.6 13.8 0.0003 21.1 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KNZ82198.1 - 2.6e-06 27.8 12.4 0.0038 18.0 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 KNZ82198.1 - 7.4e-06 25.9 4.5 0.0033 17.4 0.8 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.8 KNZ82198.1 - 0.0013 19.0 3.8 0.059 13.7 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 KNZ82198.1 - 0.0014 18.5 0.4 0.031 14.2 0.1 2.2 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 KNZ82198.1 - 0.0032 18.1 0.2 0.023 15.4 0.0 2.0 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 KNZ82198.1 - 0.019 15.0 11.4 0.026 14.5 0.2 2.9 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KNZ82198.1 - 0.034 13.9 6.0 0.057 13.2 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KNZ82198.1 - 0.045 13.7 10.1 0.9 9.5 0.9 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 KNZ82198.1 - 0.053 14.0 1.3 0.053 14.0 1.3 3.0 2 1 1 3 3 3 0 Zinc-finger double domain DUF629 PF04780.12 KNZ82198.1 - 0.094 11.2 3.3 3 6.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf_UBZ PF18439.1 KNZ82198.1 - 0.28 10.8 5.4 0.18 11.4 0.6 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 KNZ82198.1 - 0.32 11.0 1.3 0.57 10.2 0.9 1.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HE PF16278.5 KNZ82198.1 - 0.53 10.8 5.3 14 6.2 5.4 2.2 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 KNZ82198.1 - 0.62 10.1 3.7 3.4 7.8 0.3 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 KNZ82198.1 - 1.6 8.9 5.3 3.4 7.9 0.4 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-AN1 PF01428.16 KNZ82198.1 - 4.3 7.6 11.4 8.3 6.7 4.1 2.5 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 KNZ82198.1 - 6.5 7.2 8.2 0.84 10.0 0.5 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-CCCH PF00642.24 KNZ82199.1 - 1.4e-09 37.6 2.9 3.8e-09 36.2 2.9 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 KNZ82199.1 - 1.1e-07 31.6 6.7 2.1e-07 30.7 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KNZ82199.1 - 1.6e-06 27.9 9.9 2.8e-06 27.2 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KNZ82199.1 - 8.7e-06 25.5 9.8 1.6e-05 24.6 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KNZ82199.1 - 1.9e-05 24.7 6.9 4.5e-05 23.5 6.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf_CCCH_4 PF18345.1 KNZ82199.1 - 2.2e-05 24.3 4.4 5e-05 23.2 4.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-RING_UBOX PF13445.6 KNZ82199.1 - 3.9e-05 23.6 10.1 8.1e-05 22.6 10.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 KNZ82199.1 - 4.2e-05 23.6 2.9 8.7e-05 22.6 2.9 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 KNZ82199.1 - 9.2e-05 22.2 10.5 0.00017 21.4 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KNZ82199.1 - 0.00032 20.9 8.7 0.00063 20.0 8.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 KNZ82199.1 - 0.0019 18.0 3.4 0.004 16.9 3.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 KNZ82199.1 - 0.048 13.5 7.6 0.09 12.7 7.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 KNZ82199.1 - 0.092 12.6 3.1 0.19 11.6 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ATP-synt_G PF04718.15 KNZ82200.1 - 6.2e-08 33.4 0.0 1.5e-07 32.2 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit bZIP_2 PF07716.15 KNZ82201.1 - 6.1e-09 35.8 15.7 6.1e-09 35.8 15.7 1.9 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 KNZ82201.1 - 0.0036 17.4 12.7 0.0036 17.4 12.7 2.3 2 1 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KNZ82201.1 - 0.038 14.5 5.2 0.038 14.5 5.2 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor TSC22 PF01166.18 KNZ82201.1 - 0.073 13.4 1.0 0.14 12.4 1.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 KNZ82201.1 - 0.079 12.8 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region BRI3BP PF14965.6 KNZ82201.1 - 0.32 10.5 0.6 0.53 9.8 0.6 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 CUE PF02845.16 KNZ82202.1 - 9.6e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF2437 PF10370.9 KNZ82202.1 - 0.037 14.9 0.1 4.7 8.2 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) PAT1 PF09770.9 KNZ82202.1 - 3.1 5.9 13.3 4 5.6 13.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_C PF00137.21 KNZ82203.1 - 9.4e-25 86.7 26.3 5.6e-16 58.6 10.3 2.7 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.24 KNZ82203.1 - 0.014 15.0 0.3 0.014 15.0 0.3 2.8 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L G0-G1_switch_2 PF15103.6 KNZ82203.1 - 0.42 11.1 2.4 2.8 8.4 0.5 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 ODV-E18 PF10717.9 KNZ82203.1 - 1.6 8.6 4.6 0.69 9.8 0.2 2.4 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Arf PF00025.21 KNZ82204.1 - 5.2e-39 133.5 0.0 2.3e-38 131.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 KNZ82204.1 - 4.7e-11 42.5 0.0 6.4e-06 25.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 KNZ82204.1 - 4.8e-10 39.7 0.0 7.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KNZ82204.1 - 3.5e-08 33.2 0.0 5.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KNZ82204.1 - 2.8e-06 26.8 0.0 3.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KNZ82204.1 - 2.9e-06 27.3 0.0 4.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KNZ82204.1 - 5.1e-06 26.0 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KNZ82204.1 - 5.7e-05 22.7 0.0 0.019 14.5 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 KNZ82204.1 - 0.0015 18.3 0.2 0.0031 17.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KNZ82204.1 - 0.0041 17.6 0.3 0.008 16.7 0.1 1.5 2 0 0 2 2 1 1 ABC transporter AAA_23 PF13476.6 KNZ82204.1 - 0.0046 17.5 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KNZ82204.1 - 0.005 16.8 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KNZ82204.1 - 0.0074 16.6 0.0 0.018 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KNZ82204.1 - 0.0079 15.8 0.0 0.22 11.1 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 KNZ82204.1 - 0.011 16.1 0.1 0.031 14.7 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 KNZ82204.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 KNZ82204.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 KNZ82204.1 - 0.028 14.1 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 KNZ82204.1 - 0.03 14.0 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Thymidylate kinase TniB PF05621.11 KNZ82204.1 - 0.037 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DLIC PF05783.11 KNZ82204.1 - 0.045 12.6 0.0 0.27 10.0 0.1 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 KNZ82204.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 KNZ82204.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KNZ82204.1 - 0.11 13.0 0.3 0.19 12.2 0.3 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 KNZ82204.1 - 0.15 11.3 0.0 0.15 11.2 0.0 1.2 1 1 0 1 1 1 0 KAP family P-loop domain adh_short PF00106.25 KNZ82205.1 - 2.9e-38 131.3 0.3 3.9e-38 130.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KNZ82205.1 - 1.7e-30 106.3 0.1 2.5e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KNZ82205.1 - 6.3e-07 29.5 0.6 0.0013 18.6 0.2 2.2 2 0 0 2 2 2 2 KR domain Septin PF00735.18 KNZ82206.1 - 6.1e-107 357.1 0.0 6.1e-107 357.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KNZ82206.1 - 3.3e-06 27.2 0.0 8.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KNZ82206.1 - 5.6e-05 23.3 2.7 0.082 13.0 0.0 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 KNZ82206.1 - 0.0025 17.2 0.0 0.0047 16.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KNZ82206.1 - 0.015 15.2 2.2 0.018 14.9 0.2 2.1 2 1 0 2 2 2 0 RsgA GTPase Pox_A32 PF04665.12 KNZ82206.1 - 0.029 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 KNZ82206.1 - 0.055 12.8 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 KNZ82206.1 - 0.062 13.8 0.2 0.26 11.8 0.0 2.1 2 1 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 KNZ82206.1 - 0.14 11.9 0.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 KNZ82206.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KNZ82206.1 - 0.32 10.1 4.4 0.71 9.0 0.1 2.6 2 2 0 3 3 3 0 G-protein alpha subunit Voltage_CLC PF00654.20 KNZ82207.1 - 4.1e-84 282.9 38.6 6.3e-84 282.2 38.6 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 KNZ82207.1 - 2.2e-09 37.6 2.9 5.4e-06 26.8 0.4 2.8 2 0 0 2 2 2 2 CBS domain COMMD1_N PF17221.3 KNZ82207.1 - 0.19 12.0 0.0 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 COMMD1 N-terminal domain RIBIOP_C PF04950.12 KNZ82208.1 - 1.4e-99 333.2 0.0 2.4e-99 332.5 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KNZ82208.1 - 1.8e-16 60.0 0.0 1.9e-15 56.7 0.0 2.7 1 1 0 1 1 1 1 AARP2CN (NUC121) domain Myb_DNA-binding PF00249.31 KNZ82209.1 - 2.9e-11 43.4 0.2 5.7e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 KNZ82209.1 - 1.9e-10 40.9 0.0 5.1e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 KNZ82209.1 - 0.00049 20.3 0.0 0.00099 19.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 KNZ82209.1 - 2.7 7.9 10.7 6.3 6.7 10.7 1.6 1 1 0 1 1 1 0 Zinc finger, ZZ type Methyltransf_10 PF05971.12 KNZ82212.1 - 2.4e-50 171.6 0.0 1.8e-49 168.7 0.0 2.0 1 1 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 KNZ82212.1 - 0.035 13.5 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Helitron_like_N PF14214.6 KNZ82214.1 - 6.4e-58 196.1 0.5 8.1e-58 195.8 0.5 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus MH1 PF03165.16 KNZ82214.1 - 0.0023 18.1 0.4 0.012 15.9 0.1 2.2 2 2 0 2 2 2 1 MH1 domain zf-RVT PF13966.6 KNZ82218.1 - 0.084 13.6 0.8 0.34 11.6 0.8 2.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glyco_hydro_79C PF16862.5 KNZ82219.1 - 1.1e-18 68.0 0.1 4.8e-18 65.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_47 PF01532.20 KNZ82220.1 - 5.7e-132 440.9 0.0 6.7e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 S4 PF01479.25 KNZ82221.1 - 1.7e-11 43.7 0.7 1.7e-11 43.7 0.7 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KNZ82221.1 - 4.2e-07 30.8 0.1 8.9e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 KNZ82222.1 - 2.2e-43 146.2 3.6 3.3e-43 145.7 3.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e SDH_C PF18317.1 KNZ82223.1 - 0.16 11.8 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain TauD PF02668.16 KNZ82225.1 - 1.4e-44 152.9 0.2 1.6e-44 152.7 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PGI PF00342.19 KNZ82226.1 - 2e-231 768.8 1.6 3.3e-231 768.0 1.6 1.3 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-CCHC PF00098.23 KNZ82230.1 - 0.065 13.3 1.4 0.13 12.4 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Med26_C PF15693.5 KNZ82230.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal zf-C2H2_10 PF16588.5 KNZ82230.1 - 0.31 10.8 2.0 0.52 10.1 2.0 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger MFS_1 PF07690.16 KNZ82231.1 - 8.2e-27 94.0 55.0 1.1e-14 54.2 22.6 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KNZ82231.1 - 5.4 5.2 13.2 7.5 4.7 13.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cu_amine_oxid PF01179.20 KNZ82232.1 - 4e-157 523.3 0.0 4.9e-157 523.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KNZ82232.1 - 0.00012 22.4 0.1 0.00031 21.1 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KNZ82232.1 - 0.0018 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 KNZ82233.1 - 2.3e-158 527.4 0.0 2.9e-158 527.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KNZ82233.1 - 1.9e-16 60.3 0.0 4.4e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KNZ82233.1 - 1.2e-05 25.4 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RT_RNaseH PF17917.1 KNZ82236.1 - 0.0012 19.1 1.4 0.0015 18.8 0.9 1.4 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Chitin_synth_2 PF03142.15 KNZ82238.1 - 5.8e-280 929.4 0.0 8.2e-280 928.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 KNZ82238.1 - 2.8e-11 43.7 0.5 2.8e-11 43.7 0.5 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KNZ82238.1 - 6.7e-09 36.0 0.1 3.7e-08 33.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KNZ82238.1 - 0.00026 20.5 0.1 0.0097 15.4 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KNZ82238.1 - 0.026 14.3 0.0 0.24 11.2 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sugar_tr PF00083.24 KNZ82239.1 - 1.3e-26 93.4 32.8 8.4e-18 64.5 7.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KNZ82239.1 - 1.3e-20 73.6 67.1 1.5e-17 63.6 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CRAL_TRIO PF00650.20 KNZ82241.1 - 8.5e-34 116.6 0.0 1.6e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KNZ82241.1 - 0.0013 18.9 0.2 0.0023 18.1 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KNZ82241.1 - 0.0063 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Nop10p PF04135.12 KNZ82242.1 - 8e-22 77.0 0.2 9.4e-22 76.8 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Thioredoxin PF00085.20 KNZ82243.1 - 4.6e-24 84.4 0.0 5.4e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KNZ82243.1 - 2.6e-06 27.8 0.2 2e-05 25.0 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 KNZ82243.1 - 3.3e-05 23.6 0.1 0.0079 15.9 0.1 2.1 1 1 1 2 2 2 2 Redoxin Thioredoxin_8 PF13905.6 KNZ82243.1 - 3.9e-05 23.9 0.0 0.00018 21.7 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KNZ82243.1 - 0.00016 21.1 0.0 0.00019 20.9 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KNZ82243.1 - 0.00041 20.2 0.0 0.0006 19.7 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 KNZ82243.1 - 0.00069 19.8 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 KNZ82243.1 - 0.011 15.5 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 KNZ82243.1 - 0.017 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like KaiB PF07689.12 KNZ82243.1 - 0.065 13.0 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiB domain TPR_9 PF13371.6 KNZ82244.1 - 0.00067 19.7 0.0 0.0033 17.5 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat PRIMA1 PF16101.5 KNZ82244.1 - 1.3 9.1 3.9 7.8 6.6 2.7 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RdRP PF05183.12 KNZ82245.1 - 5.4e-109 365.5 0.0 7.5e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase PDZ_5 PF17817.1 KNZ82245.1 - 1.3 9.3 3.2 0.98 9.7 0.5 2.3 2 0 0 2 2 2 0 PDZ domain SMC_N PF02463.19 KNZ82246.1 - 3e-67 226.3 0.0 5.4e-67 225.5 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KNZ82246.1 - 5.8e-22 78.2 0.0 1.7e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KNZ82246.1 - 3.8e-11 43.4 0.6 1.5e-05 25.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ82246.1 - 3.7e-09 36.8 2.6 3.7e-09 36.8 2.6 4.1 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 KNZ82246.1 - 9.8e-05 22.0 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KNZ82246.1 - 1 9.9 0.0 1 9.9 0.0 5.7 4 2 0 4 4 4 0 ABC transporter WD40 PF00400.32 KNZ82248.1 - 6.1e-139 447.8 67.8 1.1e-10 41.9 0.7 16.1 15 0 0 15 15 15 15 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ82248.1 - 9.9e-52 173.2 5.4 0.00045 20.5 0.0 14.2 1 1 14 15 15 15 13 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KNZ82248.1 - 3.8e-23 80.9 24.1 0.2 11.6 0.5 14.0 14 0 0 14 14 14 6 WD40-like Beta Propeller Repeat eIF2A PF08662.11 KNZ82248.1 - 5.1e-19 68.9 2.3 0.00095 19.1 0.0 6.4 1 1 6 7 7 7 7 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 KNZ82248.1 - 7.1e-16 57.7 15.5 0.00037 19.1 0.3 6.1 2 2 6 8 8 8 6 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KNZ82248.1 - 1e-15 57.6 21.9 1.3 7.9 1.0 12.9 1 1 10 12 12 12 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KNZ82248.1 - 9.1e-11 41.9 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40_like PF17005.5 KNZ82248.1 - 2.4e-09 37.0 2.4 0.13 11.6 0.0 6.6 4 2 4 8 8 8 2 WD40-like domain AAA_16 PF13191.6 KNZ82248.1 - 2.9e-05 24.5 0.1 0.00011 22.6 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.22 KNZ82248.1 - 0.00012 21.3 1.0 0.0007 18.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain HARP PF07443.13 KNZ82248.1 - 0.00086 18.9 2.6 82 3.0 0.0 7.3 9 0 0 9 9 9 0 HepA-related protein (HARP) Glyoxal_oxid_N PF07250.11 KNZ82248.1 - 0.0011 18.2 6.4 5.7 6.1 0.0 6.2 2 2 5 8 8 8 1 Glyoxal oxidase N-terminus nos_propeller PF18764.1 KNZ82248.1 - 0.0018 18.1 7.5 62 3.6 0.0 8.0 9 0 0 9 9 9 0 Nitrous oxide reductase propeller repeat APS_kinase PF01583.20 KNZ82248.1 - 0.0032 17.4 0.0 0.0093 15.9 0.0 1.8 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 KNZ82248.1 - 0.0047 17.2 0.1 0.036 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KNZ82248.1 - 0.015 15.8 0.0 0.061 13.8 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 KNZ82248.1 - 0.033 13.9 0.0 0.23 11.2 0.0 2.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 KNZ82248.1 - 0.036 13.3 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 KNZ82248.1 - 0.042 14.2 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Glyco_hydro_67N PF03648.14 KNZ82248.1 - 0.13 12.5 0.0 1.9e+02 2.3 0.0 4.2 3 1 1 5 5 4 0 Glycosyl hydrolase family 67 N-terminus DUF4329 PF14220.6 KNZ82248.1 - 0.25 11.4 5.4 7.5 6.6 0.0 5.2 5 3 1 6 6 6 0 Domain of unknown function (DUF4329) DUF5122 PF17164.4 KNZ82248.1 - 0.25 11.6 30.7 17 5.8 0.1 11.1 12 0 0 12 12 12 0 Domain of unknown function (DUF5122) beta-propeller Proteasome_A_N PF10584.9 KNZ82248.1 - 0.96 9.2 29.7 1.7e+02 2.0 0.0 12.1 12 0 0 12 12 12 0 Proteasome subunit A N-terminal signature POT1PC PF16686.5 KNZ82250.1 - 0.017 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein gag-asp_proteas PF13975.6 KNZ82251.1 - 1.4e-06 28.8 0.0 5e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KNZ82251.1 - 3.4e-05 24.4 0.0 0.0001 22.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RT_RNaseH_2 PF17919.1 KNZ82251.1 - 0.0038 17.2 0.0 0.0085 16.1 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 KNZ82251.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase zf-CCHC PF00098.23 KNZ82252.1 - 0.28 11.3 1.2 0.52 10.5 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle LysM PF01476.20 KNZ82254.1 - 4e-08 33.2 0.0 6.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 LysM domain Ank_3 PF13606.6 KNZ82255.1 - 2.8e-07 30.3 0.1 0.0068 16.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KNZ82255.1 - 4e-07 30.4 0.0 0.024 15.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KNZ82255.1 - 3.6e-06 27.5 0.1 0.00018 22.1 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 KNZ82255.1 - 5.3e-06 26.6 0.1 0.00011 22.5 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 KNZ82255.1 - 0.00074 19.8 0.1 0.046 14.0 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) STPPase_N PF16891.5 KNZ82255.1 - 0.0047 17.3 0.2 0.0098 16.3 0.1 1.6 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain HhH-GPD PF00730.25 KNZ82256.1 - 3.6e-17 62.8 0.0 6.9e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 KNZ82256.1 - 2.6e-10 40.2 0.0 1.1e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 KNZ82256.1 - 0.00071 19.3 0.3 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF4636 PF15468.6 KNZ82256.1 - 0.75 9.4 3.1 1.2 8.8 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) EndIII_4Fe-2S PF10576.9 KNZ82256.1 - 2.9 8.4 8.2 5.4 7.5 8.2 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Gti1_Pac2 PF09729.9 KNZ82259.1 - 2.8e-20 73.2 3.5 1e-10 42.0 0.1 3.5 3 1 1 4 4 4 3 Gti1/Pac2 family Tudor-knot PF11717.8 KNZ82260.1 - 0.00036 20.3 0.0 0.0033 17.3 0.0 2.0 1 1 1 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KNZ82260.1 - 0.00039 20.3 0.0 0.00054 19.8 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 KNZ82263.1 - 0.00062 20.4 0.0 0.0086 16.7 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KNZ82263.1 - 0.004 17.7 0.0 0.039 14.5 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Sec5 PF15469.6 KNZ82265.1 - 3.9e-55 186.6 0.1 5.1e-54 183.0 0.0 2.8 2 1 1 3 3 3 1 Exocyst complex component Sec5 Sec15 PF04091.12 KNZ82265.1 - 0.047 13.1 0.0 0.16 11.3 0.0 1.9 2 1 0 2 2 2 0 Exocyst complex subunit Sec15-like DUF155 PF02582.14 KNZ82266.1 - 3.4e-54 183.6 0.1 6.5e-54 182.7 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF724 PF05266.14 KNZ82267.1 - 0.085 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AMP-binding PF00501.28 KNZ82268.1 - 9.6e-79 264.9 0.0 3.1e-78 263.3 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KNZ82268.1 - 1.6e-11 45.0 0.0 4.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 KNZ82268.1 - 0.048 14.0 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 KNZ82269.1 - 5.4e-52 173.7 0.4 4e-17 61.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_H PF00075.24 KNZ82270.1 - 1.6e-13 51.1 0.3 9.6e-13 48.5 0.3 2.0 1 1 0 1 1 1 1 RNase H His_Phos_2 PF00328.22 KNZ82271.1 - 1.5e-21 77.2 0.0 3.6e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ADH_N PF08240.12 KNZ82272.1 - 1.2e-32 112.0 3.6 2.1e-32 111.2 3.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KNZ82272.1 - 4.8e-15 55.7 0.0 8.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KNZ82272.1 - 1.6e-11 44.1 0.0 2.4e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KNZ82272.1 - 3.4e-06 28.1 0.0 5.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 KNZ82272.1 - 0.00042 19.7 1.1 0.00061 19.1 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 KNZ82272.1 - 0.0077 16.5 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Staph_opine_DH PF10100.9 KNZ82272.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase ADH_N_2 PF16884.5 KNZ82272.1 - 0.097 12.6 0.1 0.32 10.9 0.0 1.8 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase AAA_12 PF13087.6 KNZ82274.1 - 4.5e-44 150.5 0.0 6.8e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KNZ82274.1 - 8.4e-27 94.6 0.0 1.5e-12 47.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KNZ82274.1 - 5.8e-11 42.5 0.0 4.4e-10 39.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KNZ82274.1 - 2.4e-10 40.9 0.0 4.1e-09 36.9 0.0 2.8 3 1 0 3 3 3 1 AAA domain zf-C2H2_jaz PF12171.8 KNZ82274.1 - 6.6e-05 23.1 10.9 0.00049 20.3 0.7 3.9 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding UvrD-helicase PF00580.21 KNZ82274.1 - 0.0001 21.9 0.0 0.048 13.2 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain zf-met PF12874.7 KNZ82274.1 - 0.00047 20.4 2.4 0.00047 20.4 2.4 3.0 3 0 0 3 3 2 2 Zinc-finger of C2H2 type PhoH PF02562.16 KNZ82274.1 - 0.00062 19.3 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.18 KNZ82274.1 - 0.0037 17.0 0.0 3.3 7.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KNZ82274.1 - 0.0039 17.2 0.0 0.0085 16.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KNZ82274.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KNZ82274.1 - 0.022 15.2 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 KNZ82274.1 - 0.043 13.7 0.3 0.2 11.5 0.3 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 KNZ82274.1 - 0.11 12.4 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Helicase AAA_5 PF07728.14 KNZ82274.1 - 0.15 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3873 PF12989.7 KNZ82274.1 - 0.21 12.0 0.1 34 4.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) OrsD PF12013.8 KNZ82274.1 - 1.8 9.1 9.5 5.1 7.6 0.2 3.6 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 KNZ82274.1 - 1.9 9.1 7.1 0.16 12.5 1.3 2.5 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 KNZ82274.1 - 2.9 8.3 11.0 0.19 12.1 0.9 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RVP_2 PF08284.11 KNZ82275.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease G-alpha PF00503.20 KNZ82276.1 - 6.5e-137 456.4 0.0 7.7e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KNZ82276.1 - 4.7e-10 39.2 0.1 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family TniB PF05621.11 KNZ82276.1 - 0.00025 20.5 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Roc PF08477.13 KNZ82276.1 - 0.014 15.6 0.0 5.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KNZ82276.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KNZ82276.1 - 0.029 14.8 0.1 0.064 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KNZ82276.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DAP3 PF10236.9 KNZ82276.1 - 0.13 11.4 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AA_kinase PF00696.28 KNZ82277.1 - 1.2e-40 139.6 0.0 1.9e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 KNZ82277.1 - 7.8e-12 44.7 0.3 1e-05 25.2 0.1 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 KNZ82277.1 - 1.4e-11 44.0 2.1 3.3e-08 33.2 0.2 2.9 3 0 0 3 3 3 2 ACT domain ChAPs PF09295.10 KNZ82278.1 - 1.9e-146 488.2 0.0 9e-145 482.6 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 KNZ82278.1 - 1.7e-06 28.4 6.9 3.6e-05 24.2 0.4 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KNZ82278.1 - 8.4e-05 22.5 2.0 1 9.8 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 KNZ82278.1 - 0.0011 18.2 6.8 0.22 10.7 2.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 KNZ82278.1 - 0.0017 19.0 5.4 0.077 13.7 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KNZ82278.1 - 0.0017 18.6 5.3 0.41 10.9 5.1 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 KNZ82278.1 - 0.0026 17.7 11.1 4 7.8 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KNZ82278.1 - 0.025 15.2 9.1 23 5.9 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 KNZ82278.1 - 0.031 15.1 4.3 11 7.1 0.2 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.9 KNZ82278.1 - 0.058 13.1 0.0 4.3 7.0 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 KNZ82278.1 - 0.16 12.1 1.8 1.4 9.1 0.1 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF2046 PF09755.9 KNZ82279.1 - 2.1e-14 53.5 5.0 1.5e-12 47.4 4.2 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) GOLGA2L5 PF15070.6 KNZ82279.1 - 0.082 11.6 2.4 0.14 10.8 2.2 1.3 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Myc-LZ PF02344.15 KNZ82279.1 - 0.13 12.4 6.5 0.2 11.8 1.6 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain UPF0242 PF06785.11 KNZ82279.1 - 0.7 10.0 7.0 3.5 7.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HSP20 PF00011.21 KNZ82280.1 - 7.3e-11 42.1 0.0 4.3e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KNZ82280.1 - 0.0045 16.5 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Hydin_ADK PF17213.3 KNZ82280.1 - 3.4 7.9 11.9 2.1 8.6 2.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Mg_trans_NIPA PF05653.14 KNZ82281.1 - 1.4e-101 339.5 15.4 1.7e-101 339.3 15.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KNZ82281.1 - 0.0025 18.0 5.4 0.0025 18.0 5.4 3.4 3 0 0 3 3 3 2 EamA-like transporter family Creatinase_N_2 PF16189.5 KNZ82282.1 - 2.1e-51 174.2 0.1 2.4e-50 170.8 0.0 2.4 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 KNZ82282.1 - 1.4e-39 135.9 0.0 3.7e-39 134.6 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 KNZ82282.1 - 1.1e-27 95.8 0.3 1.4e-24 85.9 0.1 2.8 2 0 0 2 2 2 2 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 KNZ82282.1 - 3.6e-20 73.0 0.0 8.6e-17 62.0 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Exo_endo_phos PF03372.23 KNZ82283.1 - 1.2e-07 31.5 0.2 1.7e-07 31.0 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Retrotran_gag_2 PF14223.6 KNZ82284.1 - 2.9e-12 46.4 0.0 3.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PqqD PF05402.12 KNZ82284.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.6 1 1 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF16 PF01519.16 KNZ82285.1 - 0.22 12.0 0.6 9.3 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Vir_act_alpha_C PF10400.9 KNZ82285.1 - 0.39 11.4 3.1 0.66 10.7 1.0 2.2 2 0 0 2 2 2 0 Virulence activator alpha C-term F-box-like PF12937.7 KNZ82288.1 - 0.02 14.8 1.6 0.72 9.8 1.6 2.8 1 1 0 1 1 1 0 F-box-like PIF1 PF05970.14 KNZ82291.1 - 2.9e-32 112.3 0.1 3.3e-32 112.1 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase 4HPAD_g_N PF18671.1 KNZ82291.1 - 0.0039 16.9 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Chitin_synth_2 PF03142.15 KNZ82292.1 - 1.2e-178 595.1 0.4 1.8e-177 591.2 0.2 2.5 1 1 1 2 2 2 1 Chitin synthase Myosin_head PF00063.21 KNZ82292.1 - 3.9e-136 455.0 0.0 1.7e-135 452.9 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 KNZ82292.1 - 1.5e-18 66.4 0.3 6.2e-18 64.5 0.6 1.9 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 KNZ82292.1 - 4.6e-10 39.5 0.0 1.3e-05 25.3 0.0 3.3 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 KNZ82292.1 - 3.6e-09 36.8 0.4 3.6e-09 36.8 0.4 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KNZ82292.1 - 3.8e-08 33.5 0.0 5.3e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KNZ82292.1 - 0.0083 15.9 0.0 1.5 8.6 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 TBK1_ULD PF18396.1 KNZ82292.1 - 0.049 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain YwiC PF14256.6 KNZ82292.1 - 0.14 12.5 0.8 0.34 11.2 0.8 1.6 1 0 0 1 1 1 0 YwiC-like protein Retrotran_gag_2 PF14223.6 KNZ82293.1 - 1.8e-16 60.1 1.0 2.6e-16 59.6 1.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 KNZ82293.1 - 5.9e-05 22.7 0.6 0.00014 21.5 0.6 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger TolA_bind_tri PF16331.5 KNZ82293.1 - 0.093 12.8 0.3 0.093 12.8 0.3 1.7 2 0 0 2 2 2 0 TolA binding protein trimerisation Herpes_V23 PF01802.17 KNZ82293.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein ZapA PF05164.13 KNZ82293.1 - 0.36 11.3 3.4 1.3 9.6 3.4 2.1 1 1 0 1 1 1 0 Cell division protein ZapA WD40 PF00400.32 KNZ82295.1 - 0.073 14.0 0.7 1.3e+02 3.7 0.1 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Nop14 PF04147.12 KNZ82295.1 - 0.31 9.2 4.2 0.46 8.6 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family Mid1 PF12929.7 KNZ82296.1 - 9.9e-54 183.1 0.0 1.3e-53 182.8 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KNZ82296.1 - 0.0004 21.0 2.9 0.039 14.6 0.4 2.4 2 0 0 2 2 2 2 Fz domain DUF92 PF01940.16 KNZ82297.1 - 3.4e-55 187.0 12.1 3.5e-52 177.2 12.1 2.0 1 1 0 1 1 1 1 Integral membrane protein DUF92 C_GCAxxG_C_C PF09719.10 KNZ82297.1 - 0.45 10.8 3.2 0.85 9.9 3.2 1.5 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Glycogen_syn PF05693.13 KNZ82298.1 - 0 1093.4 0.0 0 1093.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 KNZ82298.1 - 1e-07 31.7 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KNZ82298.1 - 3.2e-07 30.8 0.0 0.0015 18.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KNZ82298.1 - 1.5e-06 28.1 1.8 3.2e-06 27.0 0.2 2.1 1 1 1 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KNZ82298.1 - 4.1e-05 24.1 0.8 0.00019 21.9 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 KNZ82298.1 - 0.0001 22.4 1.6 0.00018 21.5 0.6 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 DUF3876 PF12992.7 KNZ82298.1 - 0.073 13.2 0.0 0.86 9.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3876) Kdo PF06293.14 KNZ82300.1 - 1.4e-06 27.8 0.1 2.7e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNZ82300.1 - 3.8e-05 23.2 0.1 6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ82300.1 - 0.00076 19.5 0.3 0.0018 18.2 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KNZ82300.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase WaaY PF06176.11 KNZ82300.1 - 0.023 14.3 0.1 0.049 13.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 KNZ82300.1 - 0.038 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF737 PF05300.11 KNZ82301.1 - 0.0012 19.2 3.0 0.0016 18.8 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) ABC1 PF03109.16 KNZ82302.1 - 1.4e-25 89.7 0.0 3e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 KNZ82302.1 - 0.0088 16.0 0.0 0.052 13.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KNZ82303.1 - 1.6e-34 119.5 0.0 6.5e-34 117.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ82303.1 - 2.7e-10 40.0 0.0 2e-07 30.6 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase DUF21 PF01595.20 KNZ82305.1 - 7.3e-26 90.9 0.2 1.1e-25 90.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KNZ82305.1 - 0.017 15.6 0.3 14 6.3 0.0 3.5 3 0 0 3 3 3 0 CBS domain Amnionless PF14828.6 KNZ82306.1 - 0.059 12.2 0.8 0.53 9.0 0.0 2.1 2 0 0 2 2 2 0 Amnionless Sacchrp_dh_C PF16653.5 KNZ82307.1 - 1.7e-74 251.3 0.0 2.5e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KNZ82307.1 - 1.9e-19 70.2 0.0 3.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 KNZ82307.1 - 6.6e-15 55.6 0.0 4.1e-14 53.0 0.0 2.2 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Shikimate_DH PF01488.20 KNZ82307.1 - 0.00023 21.2 0.0 0.00049 20.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KNZ82307.1 - 0.0034 16.7 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Gp58 PF07902.11 KNZ82307.1 - 0.14 10.4 0.1 0.19 10.0 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein Gpi1 PF05024.15 KNZ82308.1 - 9.9e-59 198.6 6.3 2.3e-58 197.4 6.3 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MMPL PF03176.15 KNZ82308.1 - 0.11 11.4 0.3 0.21 10.5 0.3 1.3 1 0 0 1 1 1 0 MMPL family Ras PF00071.22 KNZ82309.1 - 9.7e-54 181.3 0.0 1.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KNZ82309.1 - 7.4e-23 81.0 0.0 1.2e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KNZ82309.1 - 1.6e-06 27.7 0.0 3.7e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KNZ82309.1 - 0.0018 18.2 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KNZ82309.1 - 0.079 13.3 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 KNZ82309.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KNZ82309.1 - 0.2 11.2 0.0 0.64 9.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Cellulase PF00150.18 KNZ82311.1 - 6.9e-29 101.1 0.8 1.2e-28 100.4 0.8 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TetR_C_19 PF17924.1 KNZ82311.1 - 0.23 12.1 1.6 0.52 10.9 0.4 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain F-box PF00646.33 KNZ82315.1 - 0.00022 21.0 0.1 0.0031 17.3 0.0 2.8 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 KNZ82315.1 - 0.0024 17.7 0.3 0.0092 15.9 0.3 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 KNZ82316.1 - 3.9e-06 26.7 1.9 7e-06 25.8 1.1 1.9 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.6 KNZ82316.1 - 0.0008 19.4 0.2 0.0028 17.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.33 KNZ82316.1 - 0.0031 17.4 3.1 0.054 13.4 3.1 2.4 1 1 0 1 1 1 1 F-box domain IBR PF01485.21 KNZ82318.1 - 0.1 12.9 8.6 4.3 7.6 6.0 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 KNZ82318.1 - 0.89 9.8 7.4 1.9 8.7 4.7 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Siva PF05458.12 KNZ82318.1 - 1.4 8.6 16.7 0.37 10.5 11.9 2.0 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Spherulin4 PF12138.8 KNZ82319.1 - 2.2e-39 135.5 0.0 2.5e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 p450 PF00067.22 KNZ82320.1 - 7.3e-55 186.5 0.0 1.4e-54 185.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 HMD PF03201.16 KNZ82321.1 - 0.067 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Kdo PF06293.14 KNZ82322.1 - 5.2e-06 25.9 0.0 7.3e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 KNZ82322.1 - 3.2e-05 23.4 0.1 5.6e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 KNZ82322.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ82322.1 - 0.0044 17.0 0.0 0.021 14.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KNZ82322.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 1 0 1 1 1 0 RIO1 family TP_methylase PF00590.20 KNZ82322.1 - 0.16 11.9 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases Pkinase PF00069.25 KNZ82323.1 - 1.6e-10 40.8 0.0 5.2e-09 35.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ82323.1 - 8.7e-06 25.2 0.0 0.00019 20.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 KNZ82323.1 - 0.015 14.3 0.1 0.025 13.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HMG_box PF00505.19 KNZ82324.1 - 0.0086 16.5 3.9 0.015 15.7 3.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box Ion_trans PF00520.31 KNZ82325.1 - 2.6e-112 374.0 97.5 3.5e-36 124.7 7.8 5.1 5 0 0 5 5 5 5 Ion transport protein PCI PF01399.27 KNZ82326.1 - 8.7e-08 32.6 2.5 0.00014 22.3 0.0 4.0 4 1 1 5 5 5 2 PCI domain Med3 PF11593.8 KNZ82326.1 - 6.8 5.8 11.2 12 4.9 11.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PIF1 PF05970.14 KNZ82329.1 - 2.6e-105 352.6 0.0 3.5e-105 352.1 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 KNZ82329.1 - 3.6e-64 216.5 0.2 1.1e-63 214.9 0.2 1.9 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 KNZ82329.1 - 3.5e-08 33.4 0.0 6.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KNZ82329.1 - 0.0082 16.5 0.0 0.035 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain 4HPAD_g_N PF18671.1 KNZ82329.1 - 0.037 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal ResIII PF04851.15 KNZ82329.1 - 0.072 13.1 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Phage_GPA PF05840.13 KNZ82329.1 - 0.13 11.3 1.4 0.28 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage replication gene A protein (GPA) MitMem_reg PF13012.6 KNZ82329.1 - 0.18 12.3 0.0 0.58 10.6 0.0 1.9 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function SEP PF08059.13 KNZ82330.1 - 1e-20 74.0 0.0 2.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 KNZ82330.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain ThylakoidFormat PF11264.8 KNZ82332.1 - 0.026 14.2 0.1 0.038 13.7 0.1 1.1 1 0 0 1 1 1 0 Thylakoid formation protein RACo_C_ter PF14574.6 KNZ82333.1 - 6.6e-07 28.6 0.0 20 4.1 0.0 6.5 1 1 7 8 8 8 6 C-terminal domain of RACo the ASKHA domain FlaG PF03646.15 KNZ82333.1 - 3.1e-06 27.3 0.0 1.6e+02 2.5 0.0 6.8 7 0 0 7 7 7 0 FlaG protein NTP_transf_8 PF12281.8 KNZ82333.1 - 5.8e-06 26.5 0.0 59 3.6 0.0 7.2 1 1 7 8 8 8 0 Nucleotidyltransferase YdfZ PF14001.6 KNZ82333.1 - 0.00025 21.4 0.0 3.7e+02 1.6 0.0 6.5 1 1 7 8 8 8 0 YdfZ protein Kdo PF06293.14 KNZ82334.1 - 3.8e-06 26.4 0.2 7.5e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KNZ82334.1 - 3.4e-05 23.4 0.2 5.8e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KNZ82334.1 - 0.0024 17.8 0.1 0.0066 16.4 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 KNZ82334.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_fungal PF17667.1 KNZ82334.1 - 0.025 13.3 0.1 0.047 12.5 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 KNZ82334.1 - 0.039 13.5 0.0 0.095 12.3 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 KNZ82334.1 - 0.12 12.0 0.2 0.21 11.1 0.2 1.4 1 0 0 1 1 1 0 RIO1 family MFMR_assoc PF16596.5 KNZ82335.1 - 0.19 12.2 6.0 0.25 11.8 6.0 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR FAM176 PF14851.6 KNZ82335.1 - 1.2 8.8 6.0 0.5 10.0 4.0 1.4 1 1 0 1 1 1 0 FAM176 family Ank_2 PF12796.7 KNZ82336.1 - 3e-80 264.9 32.8 4.7e-19 68.8 2.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KNZ82336.1 - 1.2e-71 228.1 18.7 6.4e-06 26.1 0.1 12.3 12 0 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.6 KNZ82336.1 - 3.7e-64 212.3 26.0 1.1e-09 38.6 0.1 8.2 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KNZ82336.1 - 1.5e-59 197.3 20.7 4.1e-07 30.2 0.1 11.6 2 2 10 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.30 KNZ82336.1 - 1.6e-56 186.4 35.9 1e-05 25.7 0.1 12.3 10 2 2 12 12 12 12 Ankyrin repeat VWA_3_C PF18571.1 KNZ82336.1 - 0.00013 21.8 13.4 16 5.5 0.1 7.5 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain D5_N PF08706.11 KNZ82336.1 - 0.00061 20.1 1.1 18 5.6 0.0 5.1 1 1 3 4 4 4 0 D5 N terminal like Archease PF01951.16 KNZ82336.1 - 0.0029 17.8 0.0 43 4.3 0.0 6.0 7 1 0 7 7 7 0 Archease protein family (MTH1598/TM1083) IL33 PF15095.6 KNZ82336.1 - 0.0046 16.5 0.7 1.6 8.2 0.1 3.2 3 0 0 3 3 3 1 Interleukin 33 DUF1296 PF06972.11 KNZ82336.1 - 0.049 13.8 2.5 26 5.0 0.0 5.9 8 1 1 9 9 8 0 Protein of unknown function (DUF1296) DUF2807 PF10988.8 KNZ82336.1 - 0.2 11.5 0.0 2.5 7.8 0.0 2.7 2 1 0 3 3 3 0 Putative auto-transporter adhesin, head GIN domain DUF3368 PF11848.8 KNZ82336.1 - 0.26 11.1 5.5 3.1e+02 1.3 0.0 6.2 8 0 0 8 8 8 0 Domain of unknown function (DUF3368) Pkinase PF00069.25 KNZ82338.1 - 1e-69 234.8 0.0 1.3e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KNZ82338.1 - 3.6e-31 108.4 0.0 4.7e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KNZ82338.1 - 0.00038 19.5 0.5 0.0056 15.7 0.5 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KNZ82338.1 - 0.0041 17.1 0.1 0.015 15.2 0.1 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KNZ82338.1 - 0.027 13.5 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Kinase-like PF14531.6 KNZ82338.1 - 0.048 13.0 0.1 0.15 11.4 0.0 1.7 1 1 1 2 2 2 0 Kinase-like ATP_bind_1 PF03029.17 KNZ82339.1 - 2.3e-71 240.4 0.0 3e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 KNZ82339.1 - 0.0011 18.5 0.0 0.011 15.2 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KNZ82339.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 KNZ82339.1 - 0.018 15.2 0.0 0.12 12.4 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase PAPA-1 PF04795.12 KNZ82339.1 - 0.4 11.5 2.7 0.7 10.7 2.7 1.4 1 0 0 1 1 1 0 PAPA-1-like conserved region SAD_SRA PF02182.17 KNZ82340.1 - 6.8e-42 142.8 0.2 6.9e-41 139.6 0.1 1.9 1 1 1 2 2 2 2 SAD/SRA domain OPT PF03169.15 KNZ82341.1 - 5.8e-190 633.0 62.5 6.7e-190 632.8 62.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1242 PF06842.12 KNZ82342.1 - 1.3e-18 66.5 2.2 1.7e-18 66.1 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) LST1 PF05083.13 KNZ82342.1 - 0.2 12.0 2.9 0.3 11.4 2.9 1.5 1 1 0 1 1 1 0 LST-1 protein SMC_N PF02463.19 KNZ82343.1 - 5.9e-61 205.7 17.3 3.2e-60 203.3 17.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KNZ82343.1 - 7.2e-19 68.2 2.0 1.7e-18 67.0 0.5 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KNZ82343.1 - 1.6e-11 44.6 4.6 4.7e-05 23.3 0.3 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KNZ82343.1 - 2.4e-08 34.1 1.4 2.4e-08 34.1 1.4 3.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 KNZ82343.1 - 1.3e-05 25.8 34.5 1.3e-05 25.8 34.5 6.5 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KNZ82343.1 - 0.00011 21.9 2.9 0.00011 21.9 0.0 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain LPP PF04728.13 KNZ82343.1 - 0.0079 16.6 1.6 0.0079 16.6 1.6 7.4 4 2 2 6 6 6 1 Lipoprotein leucine-zipper DUF2999 PF11212.8 KNZ82343.1 - 0.017 15.4 4.0 0.09 13.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) Spidroin_MaSp PF11260.8 KNZ82343.1 - 1.4 9.2 5.5 21 5.5 0.2 3.6 3 0 0 3 3 3 0 Major ampullate spidroin 1 and 2 DUF262 PF03235.14 KNZ82344.1 - 8.9e-14 52.2 0.1 2.4e-13 50.8 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function DUF262 Herpes_IR6 PF06307.12 KNZ82344.1 - 0.045 13.3 0.5 0.084 12.4 0.5 1.4 1 0 0 1 1 1 0 Herpesvirus IR6 protein T3SS_needle_reg PF09025.10 KNZ82344.1 - 0.16 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator RNase_PH PF01138.21 KNZ82345.1 - 1.2e-18 67.9 0.0 1.7e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KNZ82345.1 - 1.8e-09 37.5 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Trm112p PF03966.16 KNZ82346.1 - 5.6e-17 62.1 0.1 7.7e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Trm112p-like protein Dyp_perox PF04261.12 KNZ82347.1 - 1.4e-05 24.3 0.2 0.00021 20.4 0.0 2.6 3 1 0 3 3 3 1 Dyp-type peroxidase family Hydantoinase_A PF01968.18 KNZ82348.1 - 5.2e-97 324.6 0.0 9.4e-97 323.8 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KNZ82348.1 - 4.7e-57 192.6 0.1 5.4e-54 182.6 0.0 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region EF-hand_7 PF13499.6 KNZ82348.1 - 0.11 12.9 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Zf_RING PF16744.5 KNZ82349.1 - 0.15 12.2 3.7 0.47 10.6 0.2 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger LRR19-TM PF15176.6 KNZ82349.1 - 0.83 9.7 3.5 2.6 8.1 3.5 1.8 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain WD40 PF00400.32 KNZ82350.1 - 2.8e-16 59.6 18.0 0.0025 18.6 0.1 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KNZ82350.1 - 1.2e-06 28.7 3.5 0.06 13.6 0.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KNZ82350.1 - 0.0015 17.6 0.3 0.52 9.2 0.0 3.0 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Inositol_P PF00459.25 KNZ82351.1 - 1.8e-48 165.4 0.1 1.5e-47 162.4 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Methyltransf_2 PF00891.18 KNZ82352.1 - 8.8e-26 90.5 0.0 8e-24 84.1 0.0 2.2 2 0 0 2 2 2 2 O-methyltransferase domain Methyltransf_25 PF13649.6 KNZ82352.1 - 0.00023 21.8 0.0 0.00067 20.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KNZ82352.1 - 0.008 16.9 0.0 0.017 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KNZ82352.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 KNZ82352.1 - 0.08 12.8 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CEP209_CC5 PF16574.5 KNZ82353.1 - 0.05 13.8 1.0 0.08 13.1 1.0 1.3 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 PIF1 PF05970.14 KNZ82356.1 - 2.1e-53 181.8 0.1 2.3e-53 181.7 0.1 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 KNZ82356.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KNZ82356.1 - 0.0079 16.0 0.1 0.019 14.7 0.1 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 KNZ82356.1 - 0.042 13.4 0.1 0.042 13.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KNZ82356.1 - 0.057 13.4 0.0 0.39 10.7 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 KNZ82356.1 - 0.062 13.7 0.1 0.29 11.5 0.1 1.9 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KNZ82356.1 - 0.12 12.7 0.0 0.13 12.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Prefoldin PF02996.17 KNZ82357.1 - 9.3e-30 103.0 1.0 1.2e-29 102.7 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KNZ82357.1 - 6.1e-06 26.1 3.3 0.00043 20.2 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin_3 PF13758.6 KNZ82357.1 - 0.00015 21.8 0.4 0.00032 20.7 0.2 1.6 1 1 0 1 1 1 1 Prefoldin subunit COG2 PF06148.11 KNZ82357.1 - 0.0016 18.5 3.5 0.48 10.5 0.2 2.1 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Med30 PF11315.8 KNZ82357.1 - 0.0039 17.4 2.1 0.019 15.2 0.1 2.0 2 0 0 2 2 2 1 Mediator complex subunit 30 Cep57_MT_bd PF06657.13 KNZ82357.1 - 0.0086 16.5 2.4 0.011 16.2 0.2 2.0 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 AIP3 PF03915.13 KNZ82357.1 - 0.025 13.7 3.7 0.028 13.5 3.7 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DASH_Dam1 PF08653.10 KNZ82357.1 - 0.032 14.0 0.5 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Fib_alpha PF08702.10 KNZ82357.1 - 0.038 14.2 3.9 0.82 9.8 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family XkdW PF09636.10 KNZ82357.1 - 0.046 13.8 0.8 0.56 10.3 0.2 2.1 2 0 0 2 2 2 0 XkdW protein ApoLp-III PF07464.11 KNZ82357.1 - 0.049 13.7 5.6 2.1 8.4 0.4 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YscO PF07321.12 KNZ82357.1 - 0.054 13.4 1.0 0.054 13.4 1.0 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO GIT_CC PF16559.5 KNZ82357.1 - 0.082 12.8 0.8 0.082 12.8 0.8 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor HIP1_clath_bdg PF16515.5 KNZ82357.1 - 0.089 13.4 6.4 0.99 10.0 0.6 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0449 PF15136.6 KNZ82357.1 - 0.12 12.9 3.2 5.7 7.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 RasGAP_C PF03836.15 KNZ82357.1 - 0.14 12.3 6.0 3.5 7.8 0.1 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Spc7 PF08317.11 KNZ82357.1 - 0.22 10.4 8.6 0.35 9.7 1.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 KNZ82357.1 - 1.2 9.2 7.0 5.5 7.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CC2-LZ PF16516.5 KNZ82357.1 - 1.3 9.5 7.5 1.3 9.5 0.8 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator KELK PF15796.5 KNZ82357.1 - 1.3 9.5 7.4 3.6 8.1 1.0 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2347 PF09804.9 KNZ82358.1 - 1.1e-46 159.7 0.0 1.5e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 KNZ82358.1 - 0.0003 20.7 0.0 0.00053 19.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KNZ82358.1 - 0.00053 18.8 0.0 0.33 9.6 0.0 3.0 2 1 0 2 2 2 1 Transport protein Avl9 F-box-like PF12937.7 KNZ82359.1 - 1.1e-06 28.5 0.7 5.5e-06 26.2 0.1 2.4 2 0 0 2 2 2 1 F-box-like MSV199 PF10553.9 KNZ82359.1 - 0.036 14.3 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 MSV199 domain GTP_EFTU PF00009.27 KNZ82360.1 - 3.4e-60 202.9 0.0 8.2e-60 201.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KNZ82360.1 - 3.6e-37 126.8 0.1 8.4e-37 125.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KNZ82360.1 - 3.4e-30 104.0 0.0 6.9e-30 103.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KNZ82360.1 - 1.6e-22 79.3 0.2 6.2e-22 77.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KNZ82360.1 - 2e-12 47.3 0.0 6.2e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KNZ82360.1 - 3.5e-07 30.1 0.0 6.5e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 KNZ82360.1 - 0.01 15.9 0.1 0.029 14.4 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase NlpE_C PF17185.4 KNZ82360.1 - 0.12 12.7 0.1 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 NlpE C-terminal OB domain AhpC-TSA PF00578.21 KNZ82361.1 - 1.4e-35 121.9 0.0 1.4e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.9 KNZ82361.1 - 9.9e-14 50.9 0.0 1.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 KNZ82361.1 - 2.2e-12 46.9 0.0 3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin Caldesmon PF02029.15 KNZ82362.1 - 4.4 5.9 10.1 5.5 5.6 10.1 1.1 1 0 0 1 1 1 0 Caldesmon mit_SMPDase PF14724.6 KNZ82363.1 - 0.16 9.9 0.0 0.21 9.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase RNase_H PF00075.24 KNZ82366.1 - 0.00015 22.0 0.1 0.0002 21.5 0.1 1.2 1 0 0 1 1 1 1 RNase H Gti1_Pac2 PF09729.9 KNZ82367.1 - 6.9e-42 143.6 0.1 1.2e-41 142.8 0.1 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family HnRNP_M PF11532.8 KNZ82367.1 - 0.048 13.9 0.1 0.16 12.2 0.1 1.9 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M WSC PF01822.19 KNZ82368.1 - 4.3e-50 167.8 45.0 7.6e-15 54.9 3.1 4.6 4 1 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KNZ82368.1 - 1.2e-20 73.7 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KNZ82368.1 - 4.5e-15 55.7 0.0 9.4e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyco_trans_2_3 PF13632.6 KNZ82369.1 - 1.2e-42 146.1 2.5 1.2e-42 146.1 2.5 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KNZ82369.1 - 0.0093 15.8 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KNZ82369.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KNZ82369.1 - 0.078 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 KNZ82370.1 - 1.9e-17 63.3 0.2 3.3e-17 62.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SAC3_GANP PF03399.16 KNZ82371.1 - 3e-67 227.1 2.2 4.3e-67 226.6 2.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family Fer4_17 PF13534.6 KNZ82371.1 - 0.11 13.0 0.2 0.49 11.0 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain DnaJ PF00226.31 KNZ82371.1 - 0.14 12.3 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain FHA PF00498.26 KNZ82372.1 - 2.6e-12 46.9 0.1 5.9e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 FHA domain OCRL_clath_bd PF16726.5 KNZ82372.1 - 0.028 14.6 0.1 0.083 13.1 0.1 1.7 2 0 0 2 2 2 0 Inositol polyphosphate 5-phosphatase clathrin binding domain Apolipoprotein PF01442.18 KNZ82372.1 - 0.15 11.9 5.0 0.29 11.0 5.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 KNZ82372.1 - 0.36 10.9 2.8 0.3 11.2 0.1 2.2 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein EMP24_GP25L PF01105.24 KNZ82372.1 - 0.44 10.5 2.1 0.7 9.8 1.2 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Tropomyosin_1 PF12718.7 KNZ82372.1 - 0.66 10.1 2.4 2.8 8.1 0.2 2.3 2 0 0 2 2 2 0 Tropomyosin like Tup_N PF08581.10 KNZ82372.1 - 2.3 8.6 6.1 12 6.3 0.2 2.4 2 0 0 2 2 2 0 Tup N-terminal Sugar_tr PF00083.24 KNZ82374.1 - 8.1e-121 404.0 26.4 9.3e-121 403.8 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KNZ82374.1 - 2.3e-18 66.2 44.9 1.2e-13 50.8 19.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KNZ82374.1 - 0.012 15.9 2.9 0.012 15.9 2.9 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Phage_holin_3_5 PF16085.5 KNZ82374.1 - 0.13 12.4 2.7 0.33 11.1 2.7 1.7 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III MAGE PF01454.19 KNZ82375.1 - 5e-51 173.4 0.0 7.9e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 MAGE family CSRNP_N PF16019.5 KNZ82375.1 - 2 8.2 3.7 0.93 9.4 1.1 1.7 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DDDD PF10161.9 KNZ82375.1 - 5.8 6.8 6.1 19 5.1 3.5 2.7 2 0 0 2 2 2 0 Putative mitochondrial precursor protein FAA_hydrolase PF01557.18 KNZ82376.1 - 1.7e-51 175.0 0.0 2.3e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family gag-asp_proteas PF13975.6 KNZ82380.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF169 PF02596.15 KNZ82380.1 - 0.044 13.7 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ArCR, COG2043 Integrase_H2C2 PF17921.1 KNZ82381.1 - 1.4e-05 25.1 0.0 3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Pox_A6 PF04924.12 KNZ82382.1 - 0.14 11.0 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A6 protein Helitron_like_N PF14214.6 KNZ82385.1 - 0.00017 21.9 0.3 0.00033 20.9 0.3 1.5 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus BCAS2 PF05700.11 KNZ82386.1 - 0.13 11.9 2.9 0.23 11.1 2.9 1.4 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) SRCR_2 PF15494.6 KNZ82389.1 - 0.1 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Peptidase_S9 PF00326.21 KNZ82390.1 - 4.7e-38 130.8 0.0 1.3e-37 129.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KNZ82390.1 - 3.8e-06 26.4 0.0 0.0051 16.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 KNZ82390.1 - 9.1e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 KNZ82390.1 - 0.00018 21.4 1.4 0.11 12.5 0.2 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 KNZ82390.1 - 0.00024 21.0 0.0 0.00052 19.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DPPIV_N PF00930.21 KNZ82390.1 - 0.0015 17.3 0.0 0.02 13.6 0.0 2.1 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Termitomyces_sp._J132-TerJ1321.0/GCA_001263195.1_TerJ1321.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Termitomyces_sp._J132-TerJ1321.0/GCA_001263195.1_TerJ1321.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Termitomyces_sp._J132-TerJ1321.0/GCA_001263195.1_TerJ1321.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Termitomyces_sp._J132-TerJ1321.0/GCA_001263195.1_TerJ1321.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:09:36 2019 # [ok]